Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44299654-44313326 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease mutation, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria Mitochondria "HPA035636: AB_10670837, HPA061396: " "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 8.6 10.7 15.9 16.2 11.8 11.4 9.9 23.5 19.8 11.4 14.5 11.4 13.0 15.3 14.1 10.4 17.2 13.4 15.9 10.4 13.2 8.9 10.3 12.6 10.9 13.4 12.4 14.3 17.1 13.8 16.2 14.2 10.1 11.1 13.2 9.8 11.2 14.4 14.6 10.2 16.8 18.3 12.1 8.8 14.1 12.3 12.9 14.1 14.7 12.3 10.4 13.4 10.2 13.9 7.1 3.2 3.7 3.4 3.7 5.5 2.8 10.4 7.9 10.3 19.0 6.1 5.7 13.7 8.7 4.5 9.2 8.9 8.5 5.7 11.5 13.9 3.7 7.9 11.4 12.4 3.6 8.1 18.3 13.4 7.7 10.0 4.0 12.4 11.9 4.8 7.9 7.4 7.9 7.8 15.8 11.3 4.9 11.7 10.4 10.7 7.7 7.7 12.4 6.3 7.9 4.8 9.5 24.6 8.9 7.5 8.4 11.6 7.8 16.2 6.6 10.0 10.0 6.1 10.8 6.7 6.2 11.9 5.6 11.0 17.1 3.7 2.4 0.0 3.4 3.3 5.5 3.6 4.8 4.4 2.6 7.1 4.7 4.3 0.7 3.7 3.4 3.2 3.0 2.8 15.9 11.8 23.5 19.8 13.2 8.9 12.4 14.3 11.1 14.1 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503633-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.8;intestine: 49.6" "Cell line enhanced" "Detected in some" "CACO-2: 29.4;HEK 293: 9.0;HEL: 16.3;Hep G2: 8.1;RPTEC TERT1: 11.3;SH-SY5Y: 36.0" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 19.2" "Group enriched" "Detected in many" 8 "NK-cells: 11.4;T-cells: 19.2" "CAB001716, HPA002199" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Nucleoplasm, Focal adhesion sites, Cytosol" "CAB001716: , HPA002199: AB_1844428" "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favourable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favourable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 57.8 9.4 3.2 11.5 1.2 3.4 5.1 10.5 5.5 22.7 3.8 2.0 14.4 9.4 3.5 2.0 3.2 9.0 1.8 9.2 6.6 19.1 15.6 3.8 2.2 9.4 5.7 2.2 1.5 1.7 1.3 3.1 11.1 2.7 10.7 7.6 1.5 2.1 1.1 1.3 49.6 5.7 9.0 2.4 1.7 1.3 8.6 0.1 2.4 1.4 2.2 2.6 5.9 1.9 0.0 0.1 0.0 11.4 19.2 1.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 9.0 16.3 1.9 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 11.3 0.0 0.4 36.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.4 3.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.8 0.0 19.2 0.4 2.0 4.7 0.0 1.9 1.2 4.8 0.1 11.4 0.0 0.0 0.0 1.5 9.4 11.5 5.1 10.5 9.2 6.6 9.4 5.7 11.1 8.6 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713946-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 20.1 11.6 12.4 15.0 18.1 10.7 22.0 6.7 16.0 28.9 34.3 29.1 12.1 11.9 26.6 16.9 21.4 20.8 30.9 14.2 10.3 8.4 9.9 6.7 13.8 8.7 24.1 9.4 24.2 12.2 27.7 14.5 13.6 17.1 27.3 15.8 19.4 14.6 18.0 10.8 14.2 17.0 66.6 14.3 10.8 21.9 9.8 21.2 5.8 19.5 11.4 9.1 35.8 31.9 3.1 3.1 1.1 5.0 2.4 2.6 1.6 7.0 15.7 16.9 20.4 24.8 30.3 6.2 12.4 19.5 14.6 12.4 12.3 9.2 11.6 7.2 16.5 13.7 8.5 11.5 10.8 7.3 5.3 7.6 26.9 10.5 16.9 11.7 10.7 22.1 12.7 26.1 16.2 20.2 42.6 9.3 17.8 13.4 14.8 9.6 18.7 11.6 17.2 21.9 12.6 14.7 8.3 15.8 19.7 20.8 8.1 10.0 15.9 10.8 23.1 56.0 14.5 21.4 19.5 2.8 6.6 15.6 23.1 9.7 17.7 0.2 2.1 1.1 2.0 1.2 2.6 3.1 2.0 1.9 2.0 1.4 1.9 1.7 0.2 2.4 5.0 3.1 0.9 1.6 12.4 18.1 6.7 16.0 10.3 8.4 24.1 9.4 17.1 21.2 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol Cytosol "CAB026126: , HPA063761: " "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.2 13.8 10.7 5.9 12.3 9.7 6.1 7.1 8.1 7.6 5.8 27.8 9.7 2.7 10.0 7.7 11.1 10.2 8.6 7.9 4.0 12.0 6.8 3.5 8.6 14.1 10.9 25.5 18.9 11.2 8.6 10.9 10.7 7.2 8.6 6.7 12.8 10.4 9.5 10.4 4.8 5.6 8.3 3.5 21.5 9.6 13.7 11.4 7.7 11.0 5.0 12.1 7.1 6.7 5.2 8.0 5.9 3.4 5.2 3.7 3.8 5.6 5.3 6.7 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 ADAM10 "CD156c, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588807-58749978 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" 8200000 "Plasma membrane" "Nucleoplasm, Vesicles" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavourable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 25.9 11.1 15.5 17.1 17.7 15.6 20.0 25.2 17.6 18.6 20.1 15.7 12.7 13.9 19.9 11.8 17.1 13.8 18.0 18.8 17.6 13.7 20.8 14.8 25.0 26.1 23.1 12.4 13.9 13.1 10.9 11.6 36.1 14.5 23.6 16.7 14.6 12.4 19.1 8.9 15.4 15.6 12.8 30.4 40.4 18.4 8.5 18.9 38.5 27.3 9.2 14.9 30.0 19.1 6.2 12.7 26.9 23.7 9.8 12.2 12.8 11.8 26.9 7.3 8.0 9.4 13.6 18.5 10.2 30.4 7.5 10.5 12.4 15.7 5.5 31.6 9.1 24.3 4.4 10.8 10.0 8.2 5.6 9.4 9.8 11.5 10.5 6.6 27.2 11.9 8.0 5.2 7.7 14.6 5.9 15.0 13.2 4.4 21.9 7.6 10.0 3.8 9.1 24.0 14.1 17.5 32.1 8.0 5.2 11.1 12.9 17.6 7.7 13.3 10.3 9.9 11.0 76.0 9.8 8.4 18.1 6.0 13.8 12.9 17.3 12.9 18.8 10.4 8.1 21.5 12.2 5.3 8.0 7.1 12.7 6.2 8.4 7.0 26.9 9.8 23.7 5.8 10.3 12.8 15.5 17.7 25.2 16.9 17.6 13.7 23.1 12.4 14.5 18.9 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 15.0;SCLC-21H: 9.1;SH-SY5Y: 17.3;SK-MEL-30: 19.9;WM-115: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 2.8 2.8 11.5 0.7 11.7 0.4 6.8 22.7 29.0 7.8 0.9 2.0 0.0 0.7 2.7 1.1 1.2 2.4 1.2 4.0 11.6 4.0 1.8 9.6 1.0 0.8 5.8 13.4 1.2 3.6 1.0 1.5 0.9 6.2 4.1 1.0 5.0 0.8 2.1 9.2 0.6 0.7 1.6 2.2 1.0 1.8 3.9 1.2 0.0 3.0 0.2 0.8 1.0 1.5 0.5 0.4 0.6 0.1 0.0 0.2 0.0 0.5 3.8 1.4 2.2 2.8 0.0 2.7 0.1 0.0 0.5 0.2 0.4 0.0 0.0 0.2 0.1 1.2 2.5 0.1 0.0 6.9 1.8 0.0 0.0 0.3 0.0 0.1 0.0 3.4 1.9 0.3 15.0 0.1 0.2 4.6 0.2 4.6 0.0 0.0 5.6 0.0 0.0 0.0 7.5 0.0 3.7 9.1 17.3 1.4 0.0 19.9 1.3 2.3 0.0 0.4 2.9 0.3 2.3 0.0 0.0 0.0 0.0 0.0 11.3 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 11.5 11.7 22.7 29.0 11.6 4.0 5.8 13.4 6.2 1.2 ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442360 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "blood: 22.8;bone marrow: 28.1;brain: 43.9;lymphoid tissue: 59.0" "Cell line enhanced" "Detected in many" "Daudi: 15.0;Karpas-707: 20.7;RPMI-8226: 14.6;SK-BR-3: 29.7;U-266/70: 20.8;U-266/84: 27.1;U-698: 21.2" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "basal ganglia: 43.9" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in some" 10 "basal ganglia: 357.5" "Region enriched" "Detected in single" 95 "basal ganglia: 166.0" "CAB001943, HPA065566, HPA075997" Enhanced Supported "CAB001943: , HPA065566: , HPA075997: " "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" 1.0 2.4 1.9 10.4 43.9 28.1 1.5 3.4 3.8 0.8 2.0 1.7 0.3 5.4 1.4 1.4 1.0 0.9 2.4 3.5 2.4 1.8 3.5 4.3 5.1 14.8 2.6 1.6 1.2 0.8 0.0 2.1 1.4 2.3 1.6 0.8 3.3 2.7 1.5 1.2 0.9 2.6 0.7 1.3 7.5 2.8 2.0 5.7 59.0 1.3 0.9 8.6 3.8 1.3 17.7 1.1 13.7 9.0 2.2 22.8 11.2 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.2 9.3 0.5 0.9 1.7 0.1 15.0 1.0 0.2 0.3 0.9 0.0 0.0 1.8 2.6 0.2 0.0 2.1 0.1 0.3 7.5 0.1 0.0 2.8 0.0 3.3 0.1 20.7 0.0 0.2 5.2 1.6 0.6 0.0 0.1 0.7 14.6 0.0 0.1 1.5 8.7 0.4 29.7 0.1 0.3 1.4 0.2 0.9 1.4 0.2 0.1 20.8 27.1 21.2 4.7 5.1 0.1 3.0 0.8 4.8 8.6 2.6 20.1 9.6 16.1 16.9 1.1 17.7 22.8 18.3 13.7 2.2 9.0 1.1 21.4 11.2 1.9 43.9 3.4 3.8 2.4 1.8 2.6 1.6 2.3 5.7 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978357 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 131.1" "Cell line enhanced" "Detected in many" "ASC diff: 28.1;ASC TERT1: 32.0;HBEC3-KT: 28.1;hTCEpi: 70.8;hTERT-HME1: 30.2;TIME: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 17 "dendritic cells: 1.6" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA000878: , HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: " "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavourable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavourable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.23e-5)" 6.9 1.8 2.9 2.0 5.6 1.0 8.5 3.0 13.7 17.2 23.0 2.9 5.7 1.7 16.3 2.9 25.8 7.1 3.2 1.5 2.4 3.1 1.1 10.8 2.3 1.0 2.7 11.6 1.8 1.2 1.2 0.7 1.8 23.3 5.7 5.1 10.1 6.0 14.6 1.6 131.1 4.8 19.9 4.8 1.1 7.1 3.2 0.8 0.0 1.2 14.4 3.0 10.0 19.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.6 19.7 0.0 1.3 28.1 32.0 0.0 2.4 5.0 0.8 0.4 0.0 8.8 0.0 3.3 18.5 14.2 0.0 28.1 0.4 0.0 0.1 0.0 13.0 0.1 2.6 0.0 0.9 4.1 70.8 2.8 30.2 12.3 0.0 0.0 14.2 1.6 0.0 0.0 0.0 9.7 0.0 1.3 0.0 19.2 0.0 0.1 0.1 10.4 0.0 0.4 1.3 0.0 31.7 6.8 4.2 7.7 2.1 0.0 0.0 0.0 20.7 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.9 5.6 3.0 13.7 2.4 3.1 2.7 11.6 23.3 0.8 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971174-22982642 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 55.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 49.0;hTCEpi: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavourable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 2.9 2.0 1.1 2.4 1.8 0.0 4.1 1.1 1.6 11.1 2.0 1.6 4.9 0.5 8.8 4.4 12.3 4.7 7.9 3.2 2.3 0.6 15.6 55.0 8.5 2.2 1.5 1.3 8.2 5.6 5.5 1.4 12.5 2.6 9.2 1.1 7.1 5.5 11.0 1.5 31.3 1.7 4.3 0.5 2.9 2.6 4.1 1.3 7.1 15.4 5.3 6.6 3.7 10.0 1.3 1.0 2.6 1.2 2.9 2.5 0.6 10.2 12.2 16.3 6.2 1.6 2.9 13.1 10.1 13.4 23.7 21.3 26.0 10.7 0.2 10.6 20.8 33.4 12.4 49.0 29.0 0.9 1.1 0.7 19.8 29.2 18.6 1.0 0.7 9.1 51.3 9.9 38.3 9.1 0.4 0.6 21.9 8.2 1.0 1.2 1.0 16.8 2.8 13.6 0.2 23.8 16.0 0.0 1.4 30.5 9.0 1.9 12.6 1.0 8.1 10.3 20.8 1.6 9.6 0.1 0.3 0.1 1.6 0.9 4.6 2.2 1.2 0.5 1.4 0.5 0.5 0.4 1.2 2.5 0.4 1.3 1.5 0.9 2.6 2.9 0.8 1.0 0.2 0.6 1.1 1.8 1.1 1.6 2.3 0.6 1.5 1.3 2.6 1.3 AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492856-109691217 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA030804: , HPA030805: , HPA031779: AB_10603674, HPA031781: , HPA036324: , HPA036711: " "unprognostic (9.68e-3)" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (2.36e-2)" "unprognostic (3.42e-1)" "unprognostic (7.28e-2)" "unprognostic (1.41e-3)" "unprognostic (6.76e-3)" "unprognostic (1.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-4)" "unprognostic (2.58e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (8.39e-2)" "unprognostic (5.56e-2)" 4.6 4.7 7.7 5.6 8.4 4.7 8.3 13.5 8.7 5.0 6.5 8.5 4.1 5.0 6.3 11.1 6.2 11.3 5.2 6.9 9.1 10.3 7.6 4.5 6.7 5.5 9.4 4.9 6.7 4.6 15.4 33.3 4.4 11.5 5.9 6.7 3.7 7.0 6.3 6.1 5.5 6.2 5.7 11.7 6.5 6.1 22.0 7.7 20.5 11.4 4.1 5.0 5.9 4.4 11.2 2.9 15.1 4.1 4.9 6.4 1.6 2.6 1.8 7.7 13.7 7.2 4.5 5.7 4.0 5.0 4.2 5.8 2.9 5.3 5.6 2.1 3.8 4.6 2.2 4.4 9.0 11.9 4.8 4.2 4.5 2.9 5.9 5.3 2.6 3.6 8.5 7.8 10.2 5.5 4.0 4.7 3.1 5.3 4.6 3.6 1.7 2.9 6.1 4.3 5.2 6.2 5.1 9.4 8.0 4.9 4.7 6.7 6.0 6.5 5.9 4.1 2.7 5.9 2.6 2.5 2.1 3.3 8.2 6.7 2.2 15.1 2.8 6.5 5.1 1.5 4.4 10.5 5.1 6.1 2.0 11.2 6.4 5.5 5.4 4.9 4.1 2.9 3.6 1.6 7.7 8.4 13.5 8.7 9.1 10.3 9.4 4.9 11.5 7.7 AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940867-92110673 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: AB_2533235, HPA008548: AB_1078121, HPA026109: AB_1844688" "unprognostic (9.57e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (5.97e-3)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (7.59e-2)" "unprognostic (6.32e-2)" "prognostic favourable (2.10e-6)" "unprognostic (8.89e-2)" "unprognostic (1.73e-1)" "unprognostic (7.77e-2)" "unprognostic (3.96e-2)" 13.7 15.9 18.0 22.6 17.1 14.9 15.6 35.8 17.5 14.4 24.5 4.7 17.2 25.5 13.0 17.1 15.3 12.4 15.0 14.8 13.3 7.0 19.5 25.1 19.9 13.2 12.4 12.3 22.3 21.3 22.1 40.5 12.9 14.0 11.9 25.3 11.1 20.1 25.9 29.6 16.1 29.1 12.0 11.1 10.4 15.0 6.9 14.4 10.3 14.9 15.7 8.6 14.0 14.2 34.4 39.5 31.9 16.6 10.6 20.3 3.4 11.2 7.0 10.4 6.6 14.9 11.0 7.4 8.4 5.7 4.3 5.5 11.9 9.8 10.2 12.2 7.4 10.4 10.0 5.5 8.1 9.2 8.5 11.2 12.2 7.8 6.1 18.5 11.9 6.9 8.8 8.9 10.2 9.3 16.6 16.7 7.3 16.3 12.6 7.3 8.0 8.7 7.7 17.4 8.2 5.9 12.4 17.0 11.9 17.8 20.0 8.6 5.2 9.0 17.1 8.7 11.2 15.2 11.4 12.0 13.2 13.7 7.7 9.4 9.8 31.9 16.6 21.4 18.4 9.3 15.4 31.4 18.7 16.7 7.2 34.4 20.3 19.3 23.2 10.6 16.3 39.5 14.9 3.4 18.0 17.1 35.8 17.5 13.3 7.0 12.4 12.3 14.0 14.4 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favourable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favourable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.1 30.3 25.0 37.2 19.4 20.1 28.0 27.9 34.0 41.3 33.1 19.8 18.3 18.3 21.5 38.2 19.7 17.7 26.0 18.0 41.8 7.2 13.9 18.1 21.3 21.5 22.6 36.3 28.8 21.9 20.7 13.8 30.8 12.1 20.4 26.4 113.2 28.4 28.9 6.5 21.7 26.8 23.2 12.5 19.1 37.7 28.7 23.9 23.3 30.5 17.5 39.9 33.7 24.6 27.7 13.3 39.4 28.0 22.2 10.7 15.8 23.3 19.1 33.3 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631567 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 57.2" "Cell line enhanced" "Detected in some" "ASC diff: 31.8;ASC TERT1: 18.8;BJ hTERT+ SV40 Large T+: 12.3;BJ hTERT+ SV40 Large T+ RasG12V: 14.6;HBF TERT88: 11.3;HSkMC: 11.0;U-138 MG: 12.1;WM-115: 10.8" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favourable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 3.8 2.4 17.4 2.5 17.7 1.0 2.8 29.7 57.2 7.7 2.2 1.8 0.0 1.4 5.1 4.7 4.5 5.7 4.2 6.5 13.5 16.0 3.7 1.4 1.6 1.3 10.4 20.4 1.7 2.9 1.2 12.6 1.0 26.5 2.4 2.5 4.8 1.5 4.2 2.9 1.3 1.9 5.0 4.9 1.9 2.0 3.5 1.5 0.0 1.2 0.2 1.1 2.9 1.7 0.2 1.6 0.0 0.8 0.7 2.9 0.2 0.0 0.0 8.0 0.0 31.8 18.8 0.0 1.1 0.0 12.3 14.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 11.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.1 0.0 0.1 4.0 0.0 0.0 0.0 0.9 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.1 8.5 4.2 4.5 0.0 0.1 0.0 8.2 0.1 10.8 0.0 0.8 0.0 2.9 0.2 1.7 0.0 1.0 1.5 0.2 0.2 0.4 2.0 0.0 0.7 0.2 1.6 0.2 0.2 17.4 17.7 29.7 32.9 13.5 16.0 10.4 20.4 26.5 1.5 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles Vesicles "HPA036329: AB_10670714, HPA036330: , HPA042998: " "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavourable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 4.9 4.4 3.2 6.1 4.4 4.3 5.8 6.0 4.6 4.9 6.0 5.6 5.6 2.5 6.5 5.2 3.4 4.5 3.5 3.2 3.8 4.0 4.1 7.5 3.0 6.7 5.3 8.7 4.1 4.8 4.1 7.3 4.7 3.7 7.5 5.2 5.5 4.8 2.9 6.0 4.5 6.5 3.9 8.4 5.4 4.9 6.3 5.6 0.7 3.0 6.4 8.7 4.5 18.1 12.9 14.5 10.1 6.1 8.1 14.3 11.0 7.9 13.6 11.9 25.8 11.7 30.9 9.0 9.8 15.6 21.9 12.0 17.3 13.8 12.4 33.1 12.4 13.9 6.3 35.9 11.9 5.6 5.7 20.0 18.8 12.3 31.0 13.6 9.2 7.6 20.8 9.1 22.0 11.1 21.8 16.9 17.6 7.4 17.4 11.9 6.9 11.2 9.9 9.5 6.4 12.3 8.6 11.3 12.8 9.6 11.4 10.5 21.0 28.3 9.5 15.2 9.6 0.0 2.7 0.7 5.9 3.0 8.7 6.3 5.3 5.0 5.6 4.2 8.6 7.3 0.5 6.4 2.4 2.2 2.3 4.5 ANKRD12 "FLJ20053, GAC-1, KIAA0874" ENSG00000101745 "Ankyrin repeat domain 12" Q6UB98 18 9136228-9285985 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040705 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040705: AB_10673301" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.41e-3)" "unprognostic (7.25e-2)" "unprognostic (6.17e-2)" "prognostic unfavourable (6.71e-4)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (3.38e-1)" "unprognostic (2.39e-2)" "unprognostic (4.62e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.03e-2)" 17.0 10.9 22.2 23.1 26.1 19.6 15.4 48.1 25.4 17.8 18.8 10.1 18.2 13.7 14.6 15.4 16.1 12.1 16.1 12.3 19.9 13.5 14.7 16.5 14.6 22.1 20.2 18.3 16.3 16.7 15.5 16.4 19.2 17.4 15.9 13.6 9.5 15.7 20.6 25.8 21.8 18.1 17.2 21.3 20.3 15.3 29.3 23.8 11.4 18.2 13.0 19.5 24.2 22.6 18.7 19.2 51.2 10.7 8.8 19.0 5.2 4.1 2.8 3.9 2.6 6.3 6.5 3.2 6.5 6.1 2.3 3.2 2.5 3.2 5.8 3.8 4.5 3.9 2.9 2.5 6.3 6.1 3.5 2.6 2.0 3.7 4.6 6.1 8.5 3.4 5.7 3.3 5.4 3.9 6.0 45.8 5.7 2.3 4.1 4.2 1.4 2.9 3.7 5.5 21.1 3.0 6.6 9.1 3.3 6.4 3.2 4.6 3.9 5.2 8.4 17.3 8.0 13.8 6.0 13.4 20.6 10.8 8.5 3.3 6.5 27.4 8.7 25.5 14.5 7.7 16.1 18.7 18.7 13.9 5.9 17.3 19.0 14.8 51.2 8.8 10.7 19.2 13.0 5.2 22.2 26.1 48.1 25.4 19.9 13.5 20.2 18.3 17.4 23.8 APAF1 "APAF-1, CED4" ENSG00000120868 "Apoptotic peptidase activating factor 1" O14727 12 98645141-98735433 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 33.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031373, CAB069399" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB069399: AB_1611908, HPA031373: AB_10602230" "unprognostic (1.32e-1)" "unprognostic (5.12e-2)" "prognostic favourable (5.90e-4)" "unprognostic (2.21e-1)" "unprognostic (3.94e-1)" "unprognostic (8.21e-3)" "unprognostic (2.03e-3)" "unprognostic (1.35e-1)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (5.63e-2)" "unprognostic (6.04e-2)" "unprognostic (9.93e-3)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.07e-2)" 10.5 4.7 10.3 11.0 11.0 36.1 8.8 13.4 11.5 10.8 11.6 8.2 5.5 7.0 10.6 7.5 6.2 6.3 11.6 5.8 10.2 8.6 5.8 6.8 11.8 11.2 8.8 6.7 10.8 7.4 5.7 6.2 10.1 8.2 9.1 12.9 8.5 8.2 6.4 6.0 7.5 14.9 7.2 10.9 15.9 8.6 6.1 9.3 15.7 7.0 3.9 14.2 9.5 9.0 2.8 6.3 33.0 8.7 1.1 1.9 1.5 4.3 6.6 20.2 7.7 6.9 12.2 5.6 11.0 8.3 8.4 8.5 4.2 3.2 6.6 3.1 9.2 7.3 14.1 8.0 10.6 4.6 5.7 12.0 6.3 5.2 2.4 11.7 15.5 5.0 2.5 8.5 4.4 14.4 5.6 3.4 12.3 1.2 6.2 12.3 5.5 3.8 7.8 16.1 2.1 4.9 7.8 2.9 5.0 8.6 3.6 3.2 6.3 17.6 11.1 5.7 4.5 6.5 3.5 2.3 4.3 7.3 2.2 16.5 7.5 6.2 8.7 7.2 1.9 3.6 1.5 2.4 1.4 1.1 6.3 2.8 1.4 0.9 33.0 1.1 3.6 4.6 0.9 1.5 10.3 11.0 13.4 11.5 10.2 8.6 8.8 6.7 8.2 9.3 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC, WNT signaling pathway regulator" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013349 Supported "HPA013349: AB_1844913" "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 7.2 5.4 40.9 6.4 21.7 8.5 6.3 19.1 39.7 6.8 7.1 10.3 2.0 6.6 6.3 3.9 8.4 5.0 5.5 7.4 37.9 12.9 6.9 6.2 6.7 5.6 23.6 20.7 7.6 4.6 13.8 7.2 5.5 39.1 5.9 6.9 4.0 4.0 4.9 7.0 6.1 8.8 8.1 19.1 6.2 5.4 5.3 20.6 3.6 6.5 2.7 6.2 6.2 3.9 3.8 3.0 12.9 2.9 3.0 3.4 1.1 8.3 7.7 12.8 9.3 10.6 8.8 5.2 13.5 6.4 7.5 8.9 6.1 6.8 16.1 13.1 17.2 6.8 13.1 11.0 12.4 9.6 8.9 12.2 11.1 4.6 5.2 6.1 6.7 7.4 7.6 12.7 8.4 10.4 15.0 5.6 10.9 5.8 7.0 3.1 4.6 2.7 6.0 15.9 7.8 6.9 10.6 13.0 7.8 12.8 5.0 5.5 6.9 5.0 16.6 15.3 7.4 15.0 10.2 4.4 6.6 6.3 8.5 11.4 8.5 10.4 2.9 5.0 3.4 1.4 2.9 3.1 1.8 2.1 2.3 3.8 2.9 2.8 12.9 3.0 2.5 3.0 1.6 1.1 40.9 21.7 19.1 31.4 37.9 12.9 23.6 20.7 39.1 20.6 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544032-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.0" "Cell line enhanced" "Detected in some" "AF22: 11.0;BJ hTERT+: 9.6;HAP1: 14.1;LHCN-M2: 12.4;RH-30: 20.5;T-47d: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 16 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 16 "dendritic cells: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000001, HPA065701, CAB065764" Enhanced Approved Mitochondria Mitochondria "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA065701: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favourable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favourable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 10.1 1.2 0.9 1.6 0.9 0.1 10.7 0.4 1.6 34.4 1.9 2.4 25.4 0.2 20.5 20.5 2.2 17.5 4.3 5.7 0.9 1.5 6.3 49.0 1.5 0.2 1.2 0.7 14.4 1.0 0.1 2.3 0.3 1.9 28.0 0.5 3.8 1.6 36.1 8.1 3.9 1.1 7.6 1.9 0.9 1.6 9.3 1.2 5.4 3.1 2.0 1.2 6.3 13.1 0.0 5.4 0.3 0.0 0.1 0.0 0.1 0.0 4.6 11.0 0.0 0.0 0.1 0.0 5.8 9.6 0.4 0.1 0.2 0.0 0.0 0.0 0.7 0.0 14.1 0.0 0.1 0.0 1.8 0.0 1.1 0.0 0.6 0.0 0.0 4.5 0.0 1.6 0.0 3.4 4.0 1.8 12.4 1.2 0.0 0.0 4.4 0.0 0.0 20.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 8.6 5.2 0.2 0.2 2.0 0.1 2.9 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 5.4 0.0 0.1 0.9 0.9 0.4 1.6 0.9 1.5 1.2 0.7 1.9 1.2 ARHGAP32 "GC-GAP, GRIT, KIAA0712, MGC1892, RICS" ENSG00000134909 "Rho GTPase activating protein 32" A7KAX9 11 128965060-129279324 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9" "Cell line enhanced" "Detected in many" "RT4: 21.4;SK-BR-3: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038382, HPA038389, HPA061505" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA038382: , HPA038389: AB_10670972, HPA061505: " "unprognostic (1.17e-1)" "unprognostic (3.58e-2)" "unprognostic (2.54e-2)" "unprognostic (1.82e-1)" "unprognostic (3.89e-2)" "unprognostic (5.64e-2)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" "unprognostic (7.32e-2)" "unprognostic (1.34e-1)" "prognostic unfavourable (6.64e-4)" "unprognostic (1.47e-1)" "unprognostic (6.17e-3)" "unprognostic (1.17e-1)" "unprognostic (4.01e-1)" "unprognostic (5.80e-2)" "unprognostic (1.64e-2)" 4.0 5.9 22.1 3.4 32.8 1.7 9.4 4.7 46.9 8.2 12.3 5.1 1.5 18.4 7.3 8.4 21.9 12.2 6.8 3.8 9.9 6.8 6.5 4.5 5.2 1.5 6.4 21.7 10.2 13.3 14.9 5.3 7.5 5.4 6.0 14.3 4.5 13.4 4.1 6.2 16.0 19.0 5.5 4.3 2.6 10.8 9.2 8.4 5.8 3.6 12.8 12.9 8.0 13.1 1.3 1.6 0.7 2.1 3.0 1.2 0.6 6.5 3.5 10.9 0.0 3.6 3.6 7.9 2.4 3.4 1.6 1.9 8.0 13.5 0.0 3.8 4.7 14.9 5.0 6.2 3.0 0.0 1.7 0.1 1.7 3.0 1.7 0.0 0.0 3.5 8.1 1.5 9.2 1.9 0.3 0.1 2.7 5.0 5.3 0.1 2.9 3.7 13.2 3.3 1.3 1.7 21.4 10.8 4.4 3.7 23.4 4.5 12.1 2.1 3.6 5.6 2.9 3.3 4.7 0.1 0.0 0.0 2.4 14.9 3.5 0.0 0.4 0.0 0.3 2.1 1.2 0.0 0.4 0.6 1.0 1.3 0.8 0.2 0.7 3.0 0.7 1.6 0.4 0.6 22.1 32.8 4.7 46.9 9.9 6.8 6.4 21.7 5.4 8.4 ARHGAP35 "GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP" ENSG00000160007 "Rho GTPase activating protein 35" Q9NRY4 19 46918676-47005077 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, GTPase activation, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037311, HPA055184, HPA056470" Approved Supported "Nuclear bodies,Aggresome" "Nuclear bodies" Aggresome "CAB037311: AB_477435, HPA055184: , HPA056470: " "unprognostic (5.47e-3)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "unprognostic (2.40e-2)" "unprognostic (2.01e-2)" "unprognostic (7.78e-3)" "unprognostic (9.82e-3)" "unprognostic (4.41e-2)" "unprognostic (2.71e-1)" "unprognostic (2.73e-2)" "unprognostic (3.25e-2)" "unprognostic (1.92e-1)" "prognostic favourable (5.55e-8)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" 4.0 3.1 11.9 1.9 9.0 0.8 5.4 6.1 11.7 4.5 4.4 3.9 3.9 3.3 5.3 4.3 2.6 8.7 10.7 9.9 6.7 7.7 4.8 2.1 8.4 6.2 4.2 17.3 4.4 2.0 4.4 3.9 4.8 5.6 9.0 3.4 5.1 4.2 4.6 2.2 3.1 13.8 7.0 2.4 4.5 2.2 1.1 1.4 0.9 1.2 1.0 3.1 1.1 20.0 22.8 15.4 13.6 14.1 11.8 2.6 10.9 15.7 11.1 12.8 12.2 7.2 10.8 7.8 44.7 12.3 14.2 14.2 15.4 7.4 5.9 14.6 16.0 9.4 13.2 8.6 12.4 11.9 14.3 12.6 13.5 10.0 9.7 3.9 12.7 11.8 8.3 13.5 8.0 8.4 9.3 10.5 3.3 9.3 40.2 15.5 14.7 20.2 19.0 8.1 17.9 10.5 12.5 9.8 7.8 10.6 12.9 4.1 7.4 8.8 22.0 9.0 23.9 0.9 1.0 0.9 2.8 0.8 2.9 0.8 2.6 3.1 1.3 1.1 1.0 1.2 0.4 1.0 1.2 1.4 0.8 1.1 ARHGEF6 "alpha-PIX, alphaPIX, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136782088 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 21.7;HL-60: 27.0;HMC-1: 103.2;U-937: 29.0" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003578 Approved Approved Cytosol Cytosol "HPA003578: AB_1078203" "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" 22.0 10.4 16.9 15.3 15.4 14.8 13.9 6.4 14.6 6.4 8.3 12.8 3.7 4.0 8.4 6.1 4.4 4.5 9.5 27.0 21.7 13.6 5.0 4.5 13.8 20.6 20.7 10.2 9.5 2.7 8.8 4.8 24.4 15.1 6.4 6.3 8.4 6.2 5.1 37.5 4.3 9.6 9.3 14.6 20.2 6.4 3.2 14.6 2.6 4.1 8.6 20.5 8.8 7.9 3.1 8.8 31.5 8.8 5.5 9.9 6.2 0.2 0.0 1.0 0.0 2.2 5.8 0.0 0.3 1.8 0.3 1.6 0.0 0.0 1.0 0.4 1.5 0.1 1.2 0.0 0.3 5.0 0.3 21.7 0.0 0.0 0.8 27.0 103.2 6.2 0.0 1.0 0.0 0.5 0.1 4.3 3.9 0.0 12.7 16.6 0.9 0.4 4.8 7.3 0.0 0.3 5.4 0.0 1.3 0.0 0.2 0.7 0.6 11.3 0.1 1.5 0.2 1.8 1.3 0.7 0.0 10.4 6.9 29.0 2.0 20.2 7.2 31.5 6.8 8.8 8.0 3.1 7.6 5.5 8.8 2.6 7.0 6.1 4.2 5.5 6.8 2.8 9.9 6.2 16.9 15.4 6.4 14.0 21.7 13.6 20.7 10.2 15.1 14.6 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782110 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavourable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 18.6 18.4 17.4 24.9 17.0 33.8 27.8 23.6 19.1 20.3 23.7 21.7 23.9 15.8 24.1 17.3 23.2 20.6 21.9 15.5 14.8 12.8 13.7 15.9 18.8 35.6 20.3 19.2 24.1 23.9 27.5 15.8 19.3 17.2 16.5 16.4 18.9 21.4 23.1 22.6 20.6 20.7 18.4 15.4 25.9 19.5 16.5 19.8 57.3 24.8 14.2 24.5 24.4 20.4 4.3 5.3 7.4 3.3 4.7 5.1 3.5 18.9 18.0 25.6 26.6 7.4 7.1 12.0 8.9 7.7 12.2 8.7 13.2 12.8 26.8 7.8 11.5 11.5 22.2 9.8 14.3 33.2 8.7 22.8 11.7 8.8 6.1 33.7 7.3 8.2 7.0 14.4 10.3 10.5 27.2 30.0 7.9 9.0 28.4 13.1 27.0 8.4 29.7 16.9 15.2 7.6 12.8 23.9 19.7 15.6 13.2 10.7 3.9 19.2 18.4 13.1 12.7 12.2 14.4 14.3 18.8 12.3 8.0 21.6 11.6 0.4 3.3 2.9 4.0 2.9 5.1 4.3 3.2 4.9 3.1 4.3 4.0 4.4 7.4 4.7 2.8 5.3 1.5 3.5 17.4 17.0 23.6 19.1 14.8 12.8 20.3 19.2 17.2 19.8 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729665-45908040 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA063044: " "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favourable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 9.0 7.9 7.1 14.6 7.2 14.0 11.8 15.7 8.8 10.2 11.4 8.2 17.9 6.4 12.2 10.7 11.5 8.8 10.6 8.2 7.4 5.8 8.7 6.9 10.2 13.0 9.6 3.8 12.2 10.7 18.4 15.1 10.3 7.5 9.9 8.1 10.1 9.7 20.6 8.6 13.5 12.6 12.5 7.3 10.2 9.0 30.9 11.0 33.3 11.5 8.2 11.2 10.0 10.0 2.1 5.3 10.5 4.9 3.1 4.4 1.3 5.4 7.8 14.0 6.1 6.0 4.2 7.6 3.8 5.4 5.3 5.0 11.1 5.6 10.5 7.0 5.2 6.6 11.3 6.4 7.7 4.6 5.4 13.9 8.6 5.4 4.1 10.9 6.4 3.4 4.9 6.7 10.7 5.4 11.7 10.9 4.7 7.1 15.6 7.8 8.3 4.2 12.1 10.0 10.1 5.1 9.0 7.6 9.7 6.2 7.2 6.0 10.9 21.9 6.4 5.7 6.9 3.8 4.9 7.3 6.0 29.3 4.4 28.7 4.0 10.5 1.7 4.2 4.1 2.2 4.3 1.7 3.7 4.4 2.4 2.1 3.6 3.3 2.4 3.1 4.9 5.3 3.1 1.3 7.1 7.2 15.7 8.8 7.4 5.8 9.6 3.8 7.5 11.0 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901300-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 43.3 5.6 7.8 13.8 9.9 4.2 22.6 3.3 11.5 27.5 14.0 9.5 4.4 6.8 29.4 10.4 14.0 15.6 27.2 16.0 5.9 5.1 14.6 5.7 14.6 14.4 11.8 6.5 18.6 4.3 14.7 11.4 22.4 9.4 16.6 8.2 6.9 14.5 7.3 88.6 15.0 12.1 29.4 10.4 12.7 9.4 7.7 10.5 8.6 7.5 11.7 18.0 22.5 17.1 21.2 1.0 4.3 3.6 5.7 14.7 2.6 0.8 0.3 2.3 5.7 5.1 13.7 0.4 16.6 44.8 11.8 9.3 20.1 0.9 1.4 4.0 15.9 5.5 8.0 2.5 14.3 5.2 2.4 0.7 4.1 5.0 9.5 0.2 9.9 17.3 1.3 7.0 8.0 1.4 0.7 2.2 3.8 2.8 5.4 0.4 0.4 5.2 6.6 3.8 0.4 7.8 9.0 1.3 1.7 7.4 4.1 4.8 3.4 0.2 1.2 6.6 8.9 9.9 4.2 0.1 0.0 4.3 5.7 0.3 2.1 4.3 0.6 0.4 7.3 1.4 0.9 19.0 10.5 6.3 1.0 21.2 6.9 4.5 1.2 5.7 3.6 0.5 14.7 2.6 7.8 9.9 3.3 11.5 5.9 5.1 11.8 6.5 9.4 10.5 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Abnormal spindle microtubule assembly" Q8IZT6 1 197084128-197146694 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease mutation, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 62.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "plasmacytoid DC: 1.5;T-reg: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;T-cells: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB017816 Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavourable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavourable (1.25e-4)" "prognostic unfavourable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavourable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.7 0.7 0.2 12.4 0.4 13.8 1.5 0.2 0.4 1.2 2.8 0.2 0.2 2.8 0.3 1.5 8.7 0.2 0.4 0.6 0.2 0.2 0.5 1.3 1.9 7.0 0.3 0.2 0.5 0.3 0.0 0.2 1.8 0.5 0.4 2.8 0.3 1.5 0.2 0.5 4.6 3.1 0.8 0.5 4.3 1.7 6.3 0.2 62.8 0.3 5.0 6.9 1.2 2.3 0.0 1.5 0.0 0.0 0.3 2.4 0.0 19.8 11.1 18.1 11.0 1.0 2.5 6.8 15.9 11.2 15.8 12.5 7.7 15.5 20.3 5.7 12.4 20.1 15.5 6.3 19.7 18.2 11.8 14.2 26.2 7.4 0.2 21.2 10.1 0.2 0.6 12.7 8.9 16.6 17.8 24.1 16.2 7.8 17.0 9.9 8.2 3.0 13.0 24.8 14.9 5.7 5.5 9.5 13.5 22.6 11.7 5.1 13.0 8.8 12.6 9.8 9.5 16.8 28.9 6.9 9.4 11.7 7.7 5.8 19.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 2.4 0.0 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.2 0.5 0.2 ASXL1 KIAA0978 ENSG00000171456 "Additional sex combs like 1, transcriptional regulator" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA064156: " "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (8.36e-2)" "prognostic unfavourable (2.86e-4)" "unprognostic (6.69e-2)" "prognostic favourable (9.16e-4)" "unprognostic (2.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (3.21e-2)" "unprognostic (1.84e-3)" "unprognostic (5.47e-2)" "unprognostic (1.90e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-1)" 24.3 19.6 19.0 35.0 18.2 39.0 24.7 28.3 23.8 32.4 22.7 17.7 16.9 15.6 32.4 22.2 14.3 20.5 21.6 17.9 19.7 10.7 21.2 25.2 27.3 26.7 20.3 14.7 28.1 27.1 21.2 16.3 19.8 18.2 20.6 16.4 16.6 17.4 23.3 25.5 18.2 21.8 21.8 12.2 28.2 19.7 32.1 23.0 47.4 26.8 15.8 29.0 23.2 35.3 9.8 3.1 1.3 0.8 1.7 14.6 1.9 22.6 13.2 20.7 11.4 9.5 11.8 18.0 15.2 13.0 26.6 19.7 39.1 14.6 21.4 9.8 18.7 15.8 17.4 14.6 21.7 32.0 9.4 34.2 20.9 21.4 8.5 14.2 14.2 13.1 9.8 18.5 13.9 14.6 16.5 11.6 12.3 6.9 19.4 11.5 5.0 15.2 11.3 24.7 9.2 10.9 10.9 9.5 14.9 27.6 9.2 12.1 13.1 10.1 15.1 28.3 24.7 13.0 16.9 13.6 14.5 15.8 14.3 37.9 10.8 0.0 0.8 1.3 4.4 0.7 3.5 9.8 5.2 5.6 0.7 5.8 5.8 5.9 0.9 1.7 0.7 3.1 14.6 1.9 19.0 18.2 28.3 23.8 19.7 10.7 20.3 14.7 18.2 23.0 ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: AB_10673142" "unprognostic (3.66e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (2.31e-1)" "prognostic unfavourable (8.59e-5)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (7.57e-2)" "unprognostic (2.44e-2)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" 13.8 15.8 20.2 11.9 27.3 25.8 12.5 32.8 37.0 13.2 12.6 39.5 9.2 14.3 12.9 16.8 14.9 16.6 14.5 17.8 19.5 16.3 14.3 21.1 11.5 13.6 31.8 18.2 15.6 19.7 24.4 23.1 13.5 27.2 12.8 12.0 21.3 17.0 13.5 20.9 16.3 12.4 12.3 15.7 16.2 16.5 60.6 34.9 14.8 18.6 8.8 15.8 12.5 13.0 15.8 20.0 38.9 24.0 17.0 24.7 20.3 13.7 25.2 19.4 11.4 27.1 31.8 19.6 16.0 28.4 19.8 25.4 17.2 13.7 12.9 11.4 24.1 16.8 18.6 21.7 20.1 24.4 35.5 13.8 17.6 30.0 30.4 18.4 24.1 38.2 25.9 13.6 30.2 19.5 24.1 29.5 17.7 20.6 18.3 27.3 24.2 21.9 17.5 25.1 22.5 13.3 15.1 18.5 18.6 22.1 17.8 23.6 25.4 38.1 19.1 24.4 15.0 22.5 17.5 26.9 29.8 16.3 30.3 16.7 17.9 21.2 20.7 26.9 21.3 24.0 17.2 15.8 19.2 16.8 20.0 12.7 16.6 18.3 38.9 17.0 18.7 14.9 24.7 20.3 20.2 27.3 32.8 37.0 19.5 16.3 31.8 18.2 27.2 34.9 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB000102: , HPA067142: " "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.6 3.8 7.5 4.0 9.8 14.3 1.9 6.0 6.7 3.5 5.8 4.7 6.3 9.4 8.9 4.8 4.0 5.7 5.0 5.4 7.5 3.3 8.5 4.7 4.7 5.1 10.2 9.2 9.2 3.1 5.2 10.2 7.2 8.2 6.4 6.8 1.9 7.0 9.4 6.1 3.8 5.5 5.2 14.8 3.9 5.4 5.1 6.3 6.9 3.2 10.3 4.9 5.8 11.3 8.6 4.8 4.9 5.6 4.3 4.5 47.4 5.7 11.3 9.6 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavourable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.5 11.1 7.4 8.4 10.6 11.6 8.8 12.4 7.0 9.3 9.6 5.2 7.2 18.4 12.9 8.8 14.6 10.9 11.5 14.1 5.9 7.2 10.1 8.4 5.0 4.7 16.9 5.7 9.1 6.4 8.8 10.5 9.6 7.0 8.3 9.5 9.9 12.7 7.0 7.1 7.9 10.6 10.8 13.3 9.4 10.5 5.3 5.3 22.9 8.3 8.1 12.1 6.9 12.4 9.5 4.8 12.3 13.3 10.8 6.4 17.1 12.3 6.6 7.5 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX, chromatin remodeler" P46100 X 77504878-77786269 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: , HPA001906: AB_1078249, HPA064684: " "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 16.4 16.6 24.5 18.9 29.3 24.3 16.3 48.2 26.4 20.6 15.4 7.1 18.9 10.2 20.2 17.1 13.5 13.8 13.4 15.1 22.9 15.8 16.6 12.2 15.9 18.6 21.1 21.3 25.4 18.3 35.7 28.1 15.9 20.2 18.4 12.6 7.1 15.8 16.5 20.1 14.1 13.5 22.3 15.3 20.1 15.6 6.5 22.4 23.7 19.8 12.7 16.5 19.9 21.1 21.9 12.8 21.5 11.5 14.6 17.7 5.7 15.1 24.4 25.1 16.8 12.5 16.8 8.9 13.1 12.1 9.7 11.5 8.3 13.3 21.0 13.5 13.9 13.5 20.0 7.8 16.6 11.8 13.1 12.7 29.0 6.1 6.8 16.5 4.4 11.1 7.7 14.3 13.7 17.1 14.9 24.2 12.1 11.9 12.7 8.6 18.1 18.9 20.6 34.6 10.8 9.5 20.3 14.3 24.7 26.4 10.4 8.7 8.3 8.4 23.6 13.7 21.3 15.4 9.2 7.2 22.3 18.9 10.1 13.1 12.1 21.3 6.9 13.8 17.7 8.7 17.1 19.2 16.3 13.7 5.1 21.9 16.8 13.5 21.5 14.6 11.5 12.8 12.8 5.7 24.5 29.3 48.2 26.4 22.9 15.8 21.1 21.3 20.2 22.4 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561647 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 13.3;CACO-2: 24.7;Hep G2: 36.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 5.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favourable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 7.4 10.1 9.0 7.0 8.9 0.9 5.2 8.2 13.1 16.5 12.2 8.7 10.5 7.2 29.0 7.7 6.5 18.6 6.9 7.3 7.9 5.7 3.5 2.5 15.2 3.4 5.3 10.3 14.7 3.9 3.2 5.8 18.2 10.6 14.8 15.2 7.8 4.6 9.8 12.4 14.9 7.5 18.0 4.8 6.9 14.6 6.8 9.0 27.6 11.3 3.6 3.8 11.8 8.7 4.1 0.0 4.4 0.0 1.9 5.1 0.8 0.0 6.6 13.3 0.2 4.8 2.0 5.9 0.2 0.6 0.4 0.8 24.7 2.4 0.4 0.8 3.8 0.2 2.7 0.0 0.9 1.1 1.5 0.0 1.1 36.9 0.5 0.0 0.0 1.2 1.0 1.0 0.3 1.1 0.1 0.6 0.6 0.1 6.4 0.0 2.6 0.3 4.6 0.7 0.0 1.2 0.1 4.1 2.7 0.2 0.1 2.3 0.4 0.1 3.0 2.6 4.8 3.7 0.8 0.0 1.3 1.7 1.2 0.3 1.2 4.4 0.0 0.0 0.3 0.0 0.8 1.0 2.3 0.4 0.0 4.1 5.1 0.8 0.0 1.9 0.0 0.0 0.0 0.8 9.0 8.9 8.2 13.1 7.9 5.7 5.3 10.3 10.6 9.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711477-44718877 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Immunity "Amyloidosis, Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" 3200000000 "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 127.2 50.9 24.2 109.2 29.8 131.1 85.2 11.8 23.1 70.5 111.4 29.1 43.3 79.1 72.7 74.7 80.5 36.8 112.8 73.6 26.0 23.1 109.7 140.3 191.2 172.1 42.2 18.8 54.8 42.7 7.8 40.5 91.9 33.1 78.7 128.9 53.5 121.5 40.9 45.7 94.1 178.5 55.1 56.7 272.8 52.5 30.0 29.5 108.0 97.7 71.5 131.6 135.9 73.5 138.9 74.9 341.3 132.8 128.8 215.8 323.7 33.1 14.7 1.4 8.3 54.6 73.6 52.1 22.0 44.9 35.8 60.9 19.1 77.4 15.8 31.1 21.4 29.3 5.5 9.8 17.2 110.7 13.0 60.2 89.2 22.1 41.6 33.7 36.1 37.2 9.1 11.0 11.8 24.4 15.3 2.2 39.6 17.7 13.8 89.0 2.4 31.4 16.8 36.0 100.3 31.2 137.5 5.8 2.1 23.0 18.7 25.9 6.2 175.3 48.5 70.3 7.8 92.6 42.9 41.0 93.8 29.5 68.5 111.3 33.6 221.2 90.4 210.9 126.8 132.8 125.9 138.9 171.7 141.1 58.9 109.4 137.0 167.5 341.3 128.8 106.5 74.9 215.8 323.7 24.2 29.8 11.8 23.1 26.0 23.1 42.2 18.8 33.1 29.5 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401013-52410350 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: , HPA055560: " "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favourable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 13.8 17.6 35.6 14.7 33.3 37.3 13.5 21.8 50.4 12.5 17.0 16.3 11.5 12.4 14.7 14.6 21.2 12.1 15.7 16.4 41.5 15.5 16.6 19.0 14.9 15.2 19.4 27.6 16.9 16.3 30.0 11.1 14.8 19.6 14.4 14.9 15.6 17.9 14.6 24.8 40.5 13.9 14.5 10.0 16.1 13.3 37.3 14.7 18.6 15.3 12.9 16.0 14.1 11.7 5.5 8.4 11.3 5.0 3.0 8.5 3.9 15.3 17.5 21.2 18.0 20.5 13.2 23.9 15.2 19.7 24.7 19.2 21.1 14.4 22.0 7.6 21.2 12.5 22.3 24.5 15.8 21.8 21.1 27.3 37.0 21.8 19.1 25.6 24.3 19.7 32.9 27.3 14.7 19.7 23.3 19.5 18.6 13.3 30.3 35.1 23.9 21.3 13.1 17.2 21.7 15.2 24.9 8.1 26.1 18.7 5.4 22.2 15.3 35.4 21.1 22.4 20.6 26.8 28.2 29.6 38.9 31.5 24.4 27.0 26.4 3.4 5.0 7.4 8.5 3.9 4.0 5.0 6.8 6.9 3.3 5.5 4.9 6.4 11.3 3.0 3.1 8.4 6.0 3.9 35.6 33.3 21.8 50.4 41.5 15.5 19.4 27.6 19.6 14.7 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: , HPA044864: " "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 4.4 1.9 3.2 11.8 4.8 16.1 4.9 1.2 5.8 7.3 5.4 5.4 3.6 3.7 6.8 5.0 10.0 4.1 3.9 3.6 3.4 2.8 2.2 2.1 5.3 8.2 5.1 1.9 5.8 3.7 3.6 6.3 3.8 4.5 5.7 6.1 1.9 4.7 6.5 12.4 16.3 4.5 7.5 5.3 4.7 3.8 9.5 3.9 25.8 4.0 8.0 9.9 8.3 7.8 9.7 6.6 6.0 3.4 6.1 16.0 2.0 7.7 4.3 11.7 6.0 1.6 2.0 8.0 9.4 5.5 9.3 10.7 5.4 7.7 8.3 4.5 3.9 8.5 8.4 5.5 13.3 6.6 4.4 8.3 7.9 5.7 0.6 9.2 8.4 2.7 0.8 8.2 4.5 3.1 4.6 23.5 8.9 6.4 16.5 9.6 9.2 2.2 14.3 11.8 7.5 2.7 6.5 3.7 5.9 8.6 9.9 3.4 10.2 9.2 2.7 12.0 8.4 7.0 8.5 7.1 7.9 16.9 4.8 7.0 8.0 2.9 1.7 6.0 4.8 3.4 3.1 8.9 5.3 5.2 3.0 9.7 2.5 3.6 0.5 6.1 2.9 6.6 16.0 2.0 3.2 4.8 1.2 5.8 3.4 2.8 5.1 1.9 4.5 3.9 BCLAF1 "BTF, KIAA0164" ENSG00000029363 "BCL2 associated transcription factor 1" Q9NYF8 6 136256627-136289851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006484, HPA006669, HPA027770" Enhanced Enhanced "Nuclear speckles" 190000 "Nuclear speckles" "HPA006484: , HPA006669: AB_1078302, HPA027770: AB_1845484" "prognostic unfavourable (1.64e-4)" "unprognostic (1.60e-1)" "prognostic favourable (3.44e-4)" "unprognostic (1.45e-1)" "unprognostic (9.46e-3)" "unprognostic (2.29e-1)" "unprognostic (2.13e-3)" "unprognostic (1.63e-1)" "unprognostic (5.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (4.19e-3)" 22.6 20.9 19.3 20.6 33.6 93.9 26.8 56.9 31.0 27.6 23.2 13.3 18.1 15.2 25.8 21.3 22.7 22.9 12.4 17.0 20.4 19.0 19.3 22.0 19.9 22.7 24.4 19.5 33.5 20.5 34.8 50.2 25.5 27.8 21.4 23.7 14.2 23.5 18.2 26.8 22.2 20.8 23.1 22.4 22.7 22.2 16.7 27.2 38.6 24.7 21.5 25.4 24.0 23.2 22.2 25.2 35.7 20.4 29.1 24.9 13.4 18.2 15.9 37.7 31.4 12.0 10.2 19.2 34.9 21.7 23.5 25.1 22.6 12.4 38.5 21.8 26.7 17.8 42.2 23.0 29.6 21.2 26.2 47.9 22.9 24.5 13.9 80.1 30.5 13.9 11.5 33.2 20.8 20.8 42.5 19.1 24.6 21.8 31.9 9.1 27.7 16.6 29.0 47.4 17.1 17.6 35.1 32.1 22.2 34.2 16.5 13.3 15.4 16.2 28.6 18.7 27.4 22.3 34.0 16.2 29.2 53.1 11.1 25.8 21.6 15.4 16.4 24.2 21.1 20.4 21.0 22.2 19.4 17.6 25.2 19.8 24.9 22.3 35.7 29.1 19.7 14.9 14.7 13.4 19.3 33.6 56.9 31.0 20.4 19.0 24.4 19.5 27.8 27.2 BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm Nucleoplasm "HPA056308: , HPA073591: " "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavourable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" 9.1 12.8 8.7 8.7 10.5 20.6 13.3 11.5 12.0 10.0 12.6 22.7 11.9 7.8 11.1 13.9 13.6 10.4 8.6 13.0 7.1 5.4 11.2 13.3 11.4 15.2 12.9 8.4 19.8 13.6 19.7 11.9 12.5 10.7 13.2 8.2 13.7 11.1 16.5 28.8 13.6 10.3 12.9 8.6 11.4 11.5 9.8 15.8 18.4 16.0 11.4 13.5 13.8 25.5 6.5 7.3 7.6 7.1 8.2 6.8 11.8 12.9 8.6 17.5 21.4 2.0 1.5 3.0 4.4 7.0 5.6 4.6 3.6 5.2 11.8 5.2 8.2 12.1 28.5 3.7 5.0 20.6 25.9 13.1 13.2 14.1 3.4 10.6 7.6 2.6 5.5 6.2 3.6 7.6 33.7 28.5 6.9 8.3 24.0 22.2 17.2 13.4 11.7 18.1 13.3 10.3 8.2 12.5 22.7 9.2 8.2 6.9 8.8 23.4 6.2 6.1 7.7 8.9 4.9 16.9 13.1 12.3 5.3 9.7 9.3 7.6 5.0 4.5 6.8 6.1 4.3 6.5 4.7 3.9 7.3 5.5 4.7 4.8 1.1 8.2 7.1 3.1 5.5 11.8 8.7 10.5 11.5 12.0 7.1 5.4 12.9 8.4 10.7 15.8 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "Bloom syndrome RecQ like helicase" P54132 15 90717327-90816165 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 1.8 0.4 3.1 11.4 1.5 5.5 0.6 4.7 2.6 0.7 1.9 0.9 0.5 1.4 1.2 1.1 2.9 0.4 1.3 1.0 2.3 2.4 0.9 0.5 2.0 7.7 2.8 0.2 0.9 0.4 0.0 1.2 3.6 0.5 0.7 2.5 0.7 7.8 0.0 1.7 0.6 2.8 0.5 1.9 6.7 1.4 4.9 0.5 36.7 0.6 3.1 9.3 1.4 0.7 7.4 1.2 4.3 1.6 4.6 5.0 1.6 5.4 7.8 8.7 5.1 0.0 0.4 5.5 4.1 1.2 4.7 5.1 6.8 3.8 14.1 2.6 1.1 9.1 13.4 3.7 6.1 8.5 9.9 14.7 8.4 2.2 0.0 14.1 7.3 0.0 0.0 4.7 2.4 3.3 12.7 4.4 4.9 3.4 10.6 7.8 9.3 1.7 10.8 16.4 5.4 1.1 9.8 6.5 6.1 3.3 4.4 2.6 3.1 11.6 1.8 3.4 6.3 3.5 8.7 3.2 13.1 14.7 1.9 10.0 5.8 2.5 1.0 4.3 3.1 1.2 4.8 7.4 2.8 3.8 1.2 4.3 2.0 2.2 0.8 4.6 1.6 1.2 5.0 1.6 3.1 1.5 4.7 1.7 2.3 2.4 2.8 0.2 0.5 0.5 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: " "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.4 4.6 6.8 8.1 8.3 10.7 10.9 6.1 6.5 4.9 7.1 5.0 5.9 9.3 4.7 6.2 3.0 6.0 4.8 9.0 8.6 4.9 6.0 4.5 4.6 7.0 9.8 6.1 7.1 5.4 5.2 10.8 5.7 9.5 16.7 8.7 2.9 13.0 10.3 6.3 2.9 8.5 5.8 7.6 4.8 10.4 7.9 6.6 7.0 4.3 6.3 4.0 6.7 8.4 5.3 4.1 11.5 4.9 19.4 11.0 14.8 8.7 9.9 5.7 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1, DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: " "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 4.8 4.3 6.0 9.6 11.3 15.3 5.1 12.9 10.6 5.4 9.2 3.4 6.8 4.3 5.4 5.5 9.1 5.5 3.3 6.5 6.6 5.3 4.2 7.7 4.9 13.0 7.5 5.9 5.1 4.7 4.2 11.0 5.3 10.5 4.1 10.4 3.7 5.4 7.4 7.3 8.3 6.7 5.5 9.2 5.9 5.1 17.6 7.0 10.9 15.6 7.3 14.6 5.5 5.6 2.0 9.1 9.7 12.7 1.4 1.3 10.7 15.5 25.2 13.9 11.1 2.3 5.2 13.6 18.3 7.9 15.4 14.7 15.3 12.1 35.9 3.4 7.0 18.0 18.9 10.2 25.9 16.4 13.8 16.9 19.8 13.2 0.5 30.1 14.7 1.4 1.7 23.2 7.4 7.9 25.4 15.4 14.5 10.3 25.2 9.9 7.6 6.7 17.4 29.3 14.7 5.7 15.1 9.6 10.3 14.1 4.7 6.9 12.4 13.9 5.2 13.8 11.2 17.8 19.1 7.2 17.6 27.6 11.1 17.9 14.4 4.6 12.7 1.8 1.3 4.0 1.3 1.1 1.3 1.0 9.1 2.0 1.2 1.3 9.7 1.4 1.5 1.4 0.4 10.7 6.0 11.3 12.9 10.6 6.6 5.3 7.5 5.9 10.5 7.0 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2, DNA repair associated" P51587 13 32315474-32400266 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 16.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026815 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 2.4 1.0 0.6 13.8 0.6 11.6 3.2 0.6 0.6 1.8 4.0 0.2 0.2 1.4 1.5 2.7 3.0 1.0 0.7 2.1 0.6 0.7 1.0 1.4 3.5 5.3 0.7 0.5 1.4 3.3 0.4 0.7 7.0 0.8 0.9 2.0 0.1 1.8 0.3 3.3 1.8 3.2 0.8 2.1 6.6 1.5 16.9 0.1 23.2 0.9 4.8 4.2 1.3 1.7 1.3 1.9 0.4 0.2 1.5 0.8 0.0 3.9 3.5 6.0 4.5 0.6 1.6 6.2 4.3 2.7 5.0 4.6 8.2 5.3 14.0 2.8 2.1 5.4 4.9 2.5 9.6 9.1 2.6 8.9 2.2 3.2 0.2 12.7 4.4 0.3 0.3 9.1 6.3 4.0 5.8 4.9 5.7 4.5 10.1 7.5 7.2 1.9 10.0 15.5 2.7 1.3 4.3 2.3 4.3 5.2 2.2 2.1 2.6 6.3 3.1 5.7 6.1 6.3 5.9 1.9 2.9 7.2 2.9 5.1 5.4 0.1 0.2 0.2 0.3 0.2 0.1 0.9 0.4 0.2 0.2 1.3 0.6 0.8 0.4 1.5 0.2 1.9 0.4 0.0 0.6 0.6 0.6 0.6 0.6 0.7 0.7 0.5 0.8 0.1 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008419 Supported Cytosol Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (7.43e-6)" "prognostic unfavourable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.6 11.0 35.1 13.9 0.8 2.5 11.3 20.5 11.5 22.0 19.1 16.0 8.3 19.6 11.5 7.4 24.4 33.1 11.1 24.0 16.8 17.8 28.6 28.4 14.9 0.0 25.7 15.7 0.5 0.6 13.4 12.7 15.9 24.6 20.9 21.9 7.3 20.2 15.7 23.7 12.5 21.7 28.8 14.8 6.7 11.0 22.9 14.1 12.7 12.1 4.5 14.1 13.4 9.2 16.9 17.9 16.8 18.2 10.9 18.5 32.0 9.0 29.0 21.9 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavourable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.2 22.9 10.2 20.4 16.6 13.7 8.1 10.7 7.5 13.6 9.7 25.9 10.1 22.6 9.7 9.8 14.3 30.0 14.2 10.2 14.8 24.2 32.3 17.4 13.5 8.3 25.4 16.3 10.4 11.7 19.7 22.5 14.5 22.7 12.6 11.9 25.4 16.2 37.8 24.5 17.4 28.4 30.6 23.5 10.0 12.9 20.5 10.3 15.0 10.7 12.5 8.3 10.7 13.0 20.6 17.0 16.0 21.5 26.2 16.9 46.2 8.3 24.5 17.7 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871513-10923070 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 64.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073" Supported Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "CAB032961: AB_2068446, HPA043561: , HPA048073: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (8.37e-4)" 12.2 8.8 12.3 12.6 16.1 13.2 9.6 12.5 17.7 15.8 14.0 9.3 9.0 11.5 19.6 9.1 20.5 14.8 12.4 14.7 11.2 7.2 9.3 14.5 8.9 12.4 7.8 10.2 13.0 16.9 8.2 6.9 15.3 9.5 12.6 10.2 12.0 11.4 13.2 64.3 12.5 12.0 15.6 6.6 9.8 11.1 17.5 8.6 9.4 10.0 12.7 15.6 15.8 15.9 1.3 1.6 0.3 1.4 0.1 2.6 0.4 22.4 16.7 24.1 32.6 20.1 27.5 23.1 16.2 28.1 24.1 23.2 25.8 8.3 31.0 19.4 28.2 21.5 24.5 24.3 15.2 34.7 20.0 9.5 10.9 31.3 17.2 14.3 12.4 18.8 15.9 16.4 19.8 30.4 22.8 27.9 14.1 40.7 24.9 12.3 29.7 27.9 34.9 12.3 36.0 14.5 11.7 17.5 16.8 11.6 14.0 15.6 14.0 12.3 18.2 29.0 16.4 27.5 18.9 27.2 21.4 27.1 19.1 23.0 12.6 0.0 1.4 0.2 1.2 1.4 0.5 1.3 0.9 2.6 1.3 1.3 1.0 0.9 0.3 0.1 0.7 1.6 0.8 0.4 12.3 16.1 12.5 17.7 11.2 7.2 7.8 10.2 9.5 8.6 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: " "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favourable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavourable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 14.1 10.6 2.0 31.6 2.6 27.1 10.2 1.4 1.8 7.9 18.5 3.9 7.0 9.6 9.6 12.0 11.7 9.1 12.1 4.4 2.1 2.3 16.4 14.8 17.1 28.3 3.9 1.1 8.2 7.6 1.8 5.9 12.3 3.2 9.8 8.7 4.4 9.6 8.4 2.7 7.4 34.7 5.1 5.0 37.7 7.4 3.8 2.7 43.7 6.7 10.7 43.4 9.6 7.3 13.8 13.7 52.5 17.0 22.2 26.4 12.0 14.3 12.2 3.6 9.9 10.0 14.6 5.5 6.3 6.2 7.5 12.4 16.4 25.0 1.6 13.9 4.9 7.3 7.8 7.5 14.8 9.3 7.1 14.0 9.9 15.6 8.1 10.8 15.2 12.7 18.5 14.2 11.1 7.1 12.5 31.2 6.8 5.9 14.1 11.5 5.8 10.9 10.6 7.4 25.5 14.1 16.0 1.0 0.5 8.2 13.6 8.1 3.6 8.5 8.8 8.1 8.4 4.2 4.9 28.3 12.6 9.7 12.2 14.6 7.6 20.7 13.0 24.9 25.0 17.0 23.1 13.8 20.5 26.4 13.7 7.8 13.3 16.9 52.5 22.2 15.6 6.1 24.0 12.0 2.0 2.6 1.4 1.8 2.1 2.3 3.9 1.1 3.2 2.7 CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 201.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882" Approved Enhanced "Endoplasmic reticulum,Cytosol" 18000000 "Endoplasmic reticulum, Cytosol" "CAB009491: AB_2259755, HPA036881: , HPA036882: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavourable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavourable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavourable (4.98e-4)" 38.3 20.7 10.4 25.0 16.3 22.1 32.0 8.7 21.7 38.0 44.6 10.5 18.6 25.6 24.8 25.9 87.4 19.5 25.5 98.5 11.9 10.6 27.2 38.2 29.5 21.1 14.3 12.5 26.9 14.8 22.3 25.3 52.6 24.8 30.0 34.5 12.7 38.7 23.2 201.9 40.7 56.3 36.2 18.7 21.7 22.2 21.2 15.6 10.1 25.6 51.2 34.1 42.2 57.0 24.5 32.7 12.4 48.0 18.3 26.6 27.2 47.9 39.6 6.7 17.5 40.6 75.7 23.7 34.2 48.4 27.4 35.7 9.7 29.3 6.9 32.4 46.3 81.7 12.7 46.5 33.2 44.6 12.0 8.9 41.9 11.6 31.2 5.8 15.5 34.2 43.1 39.3 64.1 30.6 7.5 22.4 33.3 15.1 2.8 0.2 5.2 14.7 2.7 22.7 11.8 54.4 20.3 28.4 6.8 34.9 19.2 22.3 11.7 6.3 40.6 37.4 15.9 24.9 34.5 7.5 20.0 3.2 42.4 3.1 10.3 2.5 48.0 7.0 26.6 29.0 25.2 24.5 23.9 26.5 32.7 22.7 12.2 16.3 12.4 18.3 32.2 9.0 24.2 27.2 10.4 16.3 8.7 21.7 11.9 10.6 14.3 12.5 24.8 15.6 CBFB PEBP2B ENSG00000067955 "Core-binding factor beta subunit" Q13951 16 67029116-67101058 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038852 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA038852: AB_10795358" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (4.66e-2)" "unprognostic (3.80e-3)" "prognostic unfavourable (2.83e-4)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-3)" "unprognostic (1.88e-2)" "prognostic unfavourable (2.89e-8)" "unprognostic (1.03e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" 15.9 10.9 15.9 26.4 25.1 20.5 15.0 9.5 14.3 15.4 10.6 23.3 11.8 8.8 15.3 10.2 20.5 14.3 16.3 21.5 16.2 13.2 12.1 14.4 16.1 32.6 23.6 12.4 17.3 13.6 40.4 18.8 13.2 17.5 14.6 11.1 13.7 19.6 10.3 33.3 14.8 12.2 11.7 22.4 18.2 17.1 7.3 24.2 42.2 17.0 14.8 31.0 15.9 18.8 6.5 9.1 20.5 9.2 14.8 7.0 5.1 15.4 10.3 9.0 14.7 6.6 8.5 14.5 17.9 10.7 16.9 15.0 20.7 17.7 34.2 17.1 15.2 15.4 16.1 10.1 22.8 11.7 9.2 23.7 8.8 16.4 9.4 30.9 51.1 8.5 6.9 18.9 14.6 13.7 25.2 12.2 17.5 11.7 31.8 16.6 8.8 14.6 64.5 39.1 29.0 11.9 13.8 13.3 11.9 45.9 7.0 18.3 6.3 22.2 18.9 26.3 18.0 14.9 24.0 16.7 29.7 99.9 20.0 21.2 23.6 20.5 7.4 7.4 6.7 9.2 7.0 6.5 6.6 7.0 9.1 6.4 6.3 5.3 4.6 14.8 6.1 3.3 7.0 5.1 15.9 25.1 9.5 14.3 16.2 13.2 23.6 12.4 17.5 24.2 CCAR1 "CARP-1, CARP1, FLJ10590" ENSG00000060339 "Cell division cycle and apoptosis regulator 1" Q8IX12 10 68721012-68792377 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007856, HPA048513" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA007856: AB_1078415, HPA048513: " "unprognostic (1.71e-1)" "unprognostic (1.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (5.15e-3)" "unprognostic (1.71e-2)" "prognostic unfavourable (1.41e-5)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "prognostic favourable (4.05e-5)" "unprognostic (2.89e-2)" "unprognostic (3.21e-3)" "prognostic unfavourable (1.37e-4)" "unprognostic (1.67e-1)" "unprognostic (2.36e-1)" "unprognostic (2.24e-1)" "unprognostic (1.41e-2)" 24.2 28.0 22.6 38.7 27.9 27.8 24.6 36.9 31.7 26.0 28.7 21.5 24.7 22.7 23.9 23.7 26.5 19.7 23.2 21.6 21.3 20.5 27.4 22.3 23.4 37.5 31.7 17.9 32.1 22.9 28.6 44.3 29.2 23.6 25.0 31.1 26.0 26.7 37.9 47.0 32.3 25.4 24.5 30.4 28.6 23.5 18.9 29.9 42.1 28.5 20.6 37.4 28.8 25.0 12.4 18.6 12.3 12.8 8.8 16.0 9.1 26.4 27.7 32.0 21.4 13.9 13.4 24.9 23.7 20.4 25.9 17.8 36.5 21.6 31.2 13.1 16.3 20.9 33.4 18.8 28.4 21.3 21.0 25.0 19.1 22.6 15.8 39.4 29.4 13.4 23.4 21.8 26.9 20.7 34.0 20.2 24.9 19.1 26.2 25.0 31.9 25.9 30.7 19.1 18.6 22.6 20.2 18.5 16.1 23.3 38.4 23.3 26.0 24.2 20.2 16.1 20.3 17.3 25.5 14.0 18.4 33.5 13.5 26.6 15.2 4.9 12.8 12.3 15.5 11.5 13.8 12.3 11.0 14.9 18.6 12.4 13.3 14.0 3.1 8.8 12.8 11.8 16.0 9.1 22.6 27.9 36.9 31.7 21.3 20.5 31.7 17.9 23.6 29.9 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641087-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 94.3;WM-115: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 3.0;myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Nucleoplasm "CAB000024: AB_563678, HPA027802: " "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavourable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavourable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 52.0 11.6 9.7 6.0 9.7 0.7 22.8 3.4 7.7 15.4 8.9 15.4 19.9 8.4 18.8 23.1 37.7 11.8 31.0 23.9 10.8 8.8 14.5 68.1 22.2 3.7 12.4 5.6 6.5 31.5 83.2 16.6 38.1 10.0 30.7 6.8 24.8 25.6 21.7 2.0 43.6 10.4 16.5 12.6 12.9 19.2 4.0 7.5 9.0 17.1 23.1 23.6 21.4 22.1 3.0 3.4 0.8 0.0 0.0 0.9 0.3 47.6 19.1 6.3 0.1 19.6 20.7 13.7 75.6 28.1 8.8 5.2 21.4 37.0 0.0 34.3 39.3 34.9 0.6 20.5 15.9 0.1 3.8 0.0 4.7 21.7 4.7 0.3 0.7 11.7 4.0 12.4 4.8 15.1 0.0 0.1 69.5 20.2 0.0 2.7 11.6 21.1 0.1 20.2 1.1 41.0 29.5 1.0 25.0 0.9 17.9 47.0 10.9 0.9 63.0 43.4 12.1 18.8 51.3 94.3 56.3 0.1 37.1 0.6 131.3 0.8 0.0 0.0 0.9 0.0 0.1 3.0 0.4 0.2 3.4 2.5 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.3 9.7 9.7 3.4 7.7 10.8 8.8 12.4 5.6 10.0 7.5 CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121997-193253901 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016359, HPA030772" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016359: AB_628102, HPA030772: " "unprognostic (4.41e-2)" "unprognostic (6.22e-2)" "unprognostic (1.90e-2)" "unprognostic (5.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.53e-2)" "unprognostic (2.48e-3)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.40e-1)" "unprognostic (7.23e-3)" "unprognostic (2.17e-1)" "unprognostic (5.44e-3)" "unprognostic (3.47e-1)" "unprognostic (2.49e-1)" "unprognostic (6.73e-3)" "unprognostic (2.98e-3)" 23.4 20.0 18.1 16.8 22.9 21.0 20.1 25.6 22.6 20.4 20.1 14.5 16.3 12.0 26.8 15.2 20.6 14.9 16.4 21.4 18.4 15.0 18.8 17.1 17.2 16.6 19.7 15.9 23.3 14.5 27.1 24.8 17.3 19.4 26.9 16.2 13.6 17.3 19.0 44.5 15.0 14.5 25.6 23.9 16.0 15.7 16.3 22.1 20.6 27.1 14.1 15.8 26.8 35.0 6.6 6.7 10.2 7.0 9.0 12.5 5.2 13.3 12.0 15.9 10.2 14.9 14.5 12.2 14.4 14.0 17.4 15.3 8.2 15.9 17.4 10.2 17.7 13.1 14.4 13.6 21.3 11.0 6.8 12.6 10.9 8.0 14.0 17.1 12.6 11.8 13.2 16.3 15.6 14.8 19.1 14.1 23.3 12.3 13.9 8.5 15.3 4.5 12.5 9.6 16.6 20.4 9.3 4.8 13.1 18.0 22.2 20.5 19.1 12.4 16.5 17.0 3.9 14.4 14.7 13.2 9.8 14.3 10.2 10.5 29.6 6.6 7.0 10.2 9.3 6.8 12.5 6.6 9.2 9.2 6.7 5.4 8.4 8.7 7.4 9.0 5.7 4.9 9.3 5.2 18.1 22.9 25.6 22.6 18.4 15.0 19.7 15.9 19.4 22.1 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737225-68835548 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 125.5" "Cell line enhanced" "Detected in some" "BEWO: 105.6;CACO-2: 35.5;CAPAN-2: 49.6;HaCaT: 47.9;hTCEpi: 33.8;MCF7: 29.3;RT4: 36.5;T-47d: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "myeloid DC: 2.8;plasmacytoid DC: 8.5" "Lineage enriched" "Detected in single" 18 "dendritic cells: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" 22000000 "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: , CAB072856: , CAB072857: , HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favourable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.1 0.7 1.3 14.8 1.5 0.5 15.3 0.8 1.1 14.4 63.8 1.8 42.4 25.5 4.7 18.6 48.5 9.7 48.9 0.8 1.5 1.0 24.2 64.9 24.4 0.5 1.8 0.9 5.6 71.5 62.2 13.2 55.2 2.8 28.9 25.9 11.8 66.6 43.7 0.8 30.5 125.5 1.5 1.1 3.5 21.6 2.1 1.8 11.7 83.0 26.2 32.6 16.8 21.7 0.0 8.5 0.0 0.0 0.3 0.4 0.1 21.3 2.2 0.0 0.0 0.0 0.0 105.6 0.0 0.0 0.0 0.0 35.5 49.6 0.0 0.4 0.0 47.9 0.0 23.8 0.0 4.1 0.6 0.0 0.1 7.6 0.0 0.0 0.2 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.1 0.8 0.1 0.0 0.0 0.3 8.7 36.5 1.3 0.1 0.2 0.0 9.0 31.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.8 0.0 0.0 0.0 0.0 0.3 0.0 8.5 0.1 0.1 1.3 1.5 0.8 1.1 1.5 1.0 1.8 0.9 2.8 1.8 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.7 10.8 6.5 6.1 4.8 5.4 6.1 7.9 6.7 10.9 8.1 13.3 5.4 12.4 7.0 8.3 14.2 13.0 10.0 10.5 8.1 11.2 13.4 7.4 10.3 4.7 18.3 9.4 5.8 6.9 13.2 10.5 6.6 22.7 8.2 6.2 4.1 14.9 4.7 6.8 4.9 9.9 14.1 7.0 4.1 10.5 7.0 4.5 10.1 85.6 6.9 11.0 7.9 7.1 9.9 7.9 6.9 10.2 6.7 4.8 17.5 7.0 7.8 6.4 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687339 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 97.4;HSkMC: 71.6;hTCEpi: 92.6;LHCN-M2: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 21.0;non-classical monocyte: 27.7" "Group enriched" "Detected in many" 8 "B-cells: 8.8;dendritic cells: 8.5;monocytes: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: AB_1620493, HPA005946: " "unprognostic (7.99e-3)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "prognostic favourable (3.14e-5)" "unprognostic (1.57e-2)" "unprognostic (2.19e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (1.30e-1)" "unprognostic (7.27e-2)" "unprognostic (2.79e-2)" "unprognostic (7.55e-3)" "prognostic favourable (4.95e-5)" "unprognostic (8.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (3.21e-2)" 81.2 27.0 8.2 21.9 29.8 22.0 38.0 4.8 13.7 25.2 60.8 13.9 10.2 39.8 17.5 17.7 63.5 49.4 47.3 35.9 22.2 8.4 29.1 102.2 55.8 6.3 16.6 4.9 59.1 45.5 12.8 22.8 38.6 44.1 42.0 40.7 8.8 18.0 11.4 98.6 43.5 144.9 40.2 29.6 13.6 25.2 25.3 10.3 6.6 22.7 42.2 27.4 50.5 44.4 8.8 8.5 1.8 27.7 0.2 1.1 13.3 3.0 12.4 9.6 0.2 33.8 60.5 17.6 50.3 40.8 6.2 24.5 1.1 2.9 2.0 1.8 31.5 6.9 0.4 55.5 10.1 4.0 2.5 0.3 10.3 15.4 97.4 0.0 15.1 71.6 92.6 57.1 18.0 32.4 0.5 14.2 72.2 6.4 0.4 1.2 1.2 1.8 6.1 7.9 3.5 11.0 23.1 4.3 4.2 11.6 1.0 2.3 3.8 12.6 17.9 10.9 10.3 0.7 4.1 23.9 4.6 6.1 14.1 1.1 30.3 0.0 9.3 0.2 0.2 21.0 0.3 8.8 0.4 0.3 8.0 5.7 0.1 0.1 1.8 0.2 27.7 8.5 1.1 13.3 8.2 29.8 4.8 13.7 22.2 8.4 16.6 4.9 44.1 10.3 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722371 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: " "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favourable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavourable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavourable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 29.8 30.9 30.2 25.0 30.0 40.2 45.3 64.5 50.6 31.6 34.4 35.6 19.9 29.2 33.1 19.8 26.0 24.3 24.3 21.2 33.0 29.5 20.8 23.3 29.2 38.5 42.9 25.1 46.2 15.1 22.2 15.9 26.8 26.3 25.1 22.2 31.4 23.5 24.2 48.8 26.1 26.4 19.4 46.0 34.3 19.4 19.2 39.0 43.0 29.4 21.4 25.5 34.1 29.1 6.2 3.3 19.2 4.5 6.2 10.6 2.9 12.8 6.4 34.3 5.9 11.8 6.7 16.8 12.1 19.2 16.7 20.6 18.3 14.6 0.1 4.6 6.9 12.3 16.0 5.9 15.0 21.8 11.3 10.0 17.6 18.4 15.8 8.5 7.1 7.4 12.8 5.5 16.1 9.9 10.7 36.7 5.9 16.5 11.9 12.2 13.7 6.0 8.8 11.2 21.5 8.0 13.9 13.0 21.4 17.3 12.5 22.6 6.6 19.1 6.7 8.3 13.2 7.5 11.7 31.8 21.0 11.6 10.3 12.8 8.0 4.5 3.1 6.8 5.4 3.1 5.6 6.2 6.9 6.5 3.2 4.8 7.4 5.2 19.2 6.2 4.5 3.3 10.6 2.9 30.2 30.0 64.5 50.6 33.0 29.5 42.9 25.1 26.3 39.0 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967753-21995301 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 22.6;pituitary gland: 39.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 50.0;HEK 293: 56.7;HeLa: 53.1;SK-MEL-30: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 22.6" "Group enriched" "Detected in many" 8 "B-cells: 7.2;T-cells: 22.6" "Low region specificity" "Detected in many" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: " "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavourable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favourable (5.19e-4)" "prognostic unfavourable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavourable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 5.4 8.6 2.9 4.5 3.9 1.8 5.3 1.7 3.1 1.2 2.5 4.4 0.1 1.2 1.2 1.9 6.3 3.0 2.6 0.7 1.7 1.0 0.9 1.2 3.0 3.0 3.6 1.6 1.5 1.5 8.5 39.3 6.7 5.0 1.9 1.1 1.2 2.4 2.9 0.9 1.3 3.7 1.0 3.0 8.9 6.0 13.0 1.9 3.9 1.4 3.0 14.0 2.7 1.5 7.2 0.2 0.8 1.8 0.4 22.6 2.2 2.1 0.0 0.3 14.1 0.1 0.1 6.1 2.3 0.0 19.6 34.9 3.5 50.0 7.2 32.2 1.6 6.0 5.9 36.4 15.8 30.9 56.7 0.0 53.1 2.3 1.5 3.5 3.0 3.8 0.0 19.8 11.0 2.0 0.0 32.9 17.9 0.1 0.3 0.0 0.4 29.2 0.0 13.3 26.4 4.0 0.0 33.0 2.3 38.0 6.3 53.0 7.5 0.1 6.5 0.1 0.4 0.0 0.1 14.7 8.3 29.4 0.0 9.4 0.1 0.8 1.3 0.2 6.2 0.6 9.7 7.2 8.0 11.0 0.2 7.0 0.5 4.7 0.4 0.4 1.8 0.0 22.6 2.2 2.9 3.9 1.7 3.1 1.7 1.0 3.6 1.6 5.0 1.9 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974633 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavourable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavourable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 42.1 12.6 5.9 10.7 7.9 14.9 31.7 4.3 5.7 13.1 13.0 8.7 7.7 6.6 17.1 13.9 11.5 8.4 13.7 20.1 5.7 3.1 7.4 3.3 7.9 11.0 13.7 5.3 22.5 9.4 23.1 5.7 3.1 3.9 10.3 5.7 6.0 5.4 12.2 9.2 8.5 7.9 15.1 7.5 8.5 5.3 5.3 8.9 54.2 8.0 4.9 9.8 17.4 21.7 3.4 7.4 12.2 2.5 6.0 14.1 3.8 13.8 5.7 1.0 19.1 19.7 2.8 0.2 13.2 13.4 22.2 19.5 0.3 4.7 27.2 11.9 11.2 1.7 12.9 1.7 10.9 16.4 17.3 20.6 43.6 3.5 1.0 14.3 9.4 1.0 0.3 6.0 2.6 5.8 9.2 0.0 12.9 3.4 18.4 6.9 0.0 14.0 22.0 18.0 0.0 7.0 5.8 9.7 22.7 18.0 12.7 4.2 6.3 48.6 4.6 25.5 9.8 15.4 0.2 27.9 26.5 22.4 0.0 52.3 22.4 12.2 2.5 11.0 5.2 1.4 6.0 3.4 7.7 6.8 6.1 1.9 4.3 4.1 0.2 6.0 0.6 7.4 14.1 3.8 5.9 7.9 4.3 5.7 5.7 3.1 13.7 5.3 3.9 8.9 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT/enhancer binding protein alpha" P49715 19 33299934-33302564 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 52.3;liver: 44.3" "Cell line enhanced" "Detected in some" "BEWO: 42.6;Hep G2: 22.8;NB-4: 23.5;THP-1: 85.0;U-937: 27.2" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 11.0;non-classical monocyte: 11.8" "Group enriched" "Detected in many" 13 "dendritic cells: 4.1;granulocytes: 11.0;monocytes: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA052734: , HPA065037: , HPA067937: " "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 40.7 1.5 2.3 7.6 4.6 8.4 52.3 2.1 4.0 3.5 9.0 5.2 1.1 9.0 2.2 2.1 6.1 2.4 6.4 6.6 3.9 2.4 2.0 44.3 39.9 10.3 4.1 3.1 1.3 9.0 4.5 1.7 17.4 2.7 3.8 5.1 1.9 5.6 1.6 15.4 23.7 12.7 2.9 6.6 3.0 3.5 1.2 2.6 2.2 2.5 10.7 3.5 5.4 7.9 0.1 4.1 11.0 11.8 0.0 0.6 1.5 0.5 1.0 0.0 1.5 12.3 0.0 42.6 0.0 0.3 0.0 0.0 5.1 0.0 0.0 0.6 0.0 1.9 1.2 0.1 0.0 7.3 1.5 0.0 0.0 22.8 0.2 7.5 9.1 0.4 5.5 0.0 0.0 0.0 0.4 0.0 0.0 2.6 0.0 23.5 1.0 0.5 0.0 0.0 0.2 0.0 3.7 0.0 0.3 0.1 0.1 0.1 2.9 85.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 27.2 0.0 11.0 6.0 0.0 0.6 9.4 0.6 0.0 0.1 0.4 4.1 0.1 0.2 0.4 2.1 0.0 11.8 0.2 0.0 1.5 2.3 4.6 2.1 4.0 3.9 2.4 4.1 3.1 2.7 2.6 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196651878-196747504 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 295.2" "Cell line enhanced" "Detected in many" "ASC diff: 25.2;HHSteC: 31.8;HSkMC: 31.0;RH-30: 23.2;RT4: 56.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 16.5" "Lineage enriched" "Detected in single" 27 "T-cells: 16.5" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" 395836666667 110000000000 Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: , HPA049176: , HPA053326: " "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 28.6 5.5 1.6 3.7 3.8 0.1 8.8 2.6 2.7 10.4 9.1 1.0 3.9 3.7 2.5 8.7 15.2 3.4 17.0 47.3 2.0 1.2 7.0 295.2 11.0 10.3 5.3 1.7 40.9 1.9 1.7 4.3 5.1 5.3 10.3 10.4 6.3 19.0 3.3 10.0 11.5 8.1 12.6 4.2 3.3 5.8 6.4 2.9 0.7 22.0 22.8 5.8 17.2 16.8 0.0 0.1 0.6 0.1 0.0 16.5 1.0 0.0 16.1 0.0 0.0 25.2 14.3 0.0 6.5 15.9 0.9 3.5 0.0 3.0 0.0 2.4 0.0 0.5 0.0 5.9 0.6 0.3 0.0 4.8 19.1 0.0 31.8 0.2 0.0 31.0 0.1 4.7 2.0 19.8 18.1 0.6 22.5 0.0 0.1 0.0 0.1 0.0 0.0 23.2 5.1 0.0 56.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 19.2 0.2 0.2 0.2 0.2 0.0 0.0 3.4 0.0 1.4 0.0 0.1 0.0 1.8 0.0 16.5 0.0 6.0 3.5 0.1 0.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 1.0 1.6 3.8 2.6 2.7 2.0 1.2 5.3 1.7 5.3 2.9 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavourable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 23.5 34.9 21.9 50.0 33.5 27.2 25.9 29.4 25.1 28.1 29.5 29.3 38.5 18.6 37.2 35.4 29.1 28.0 40.3 52.8 23.5 19.2 29.5 25.0 25.5 30.9 33.6 19.4 34.6 27.4 58.4 25.3 29.5 27.2 21.5 26.0 26.5 24.8 46.2 33.7 31.1 24.4 36.6 30.3 29.4 27.2 29.7 28.9 75.7 38.4 33.7 38.4 34.7 24.3 12.6 16.8 12.8 9.1 13.5 16.7 5.8 20.5 18.7 46.5 17.4 19.1 21.5 27.3 22.8 22.2 25.2 23.2 31.2 16.0 44.2 9.1 25.7 18.4 43.6 25.1 34.0 33.0 22.4 61.7 29.1 19.5 16.6 48.4 29.6 20.7 12.5 24.3 17.1 29.3 48.5 22.1 23.9 25.7 45.9 15.8 44.5 17.7 39.4 28.6 24.1 15.9 24.3 22.0 28.3 29.3 32.6 22.6 14.9 27.6 27.2 25.7 54.8 18.8 26.6 35.8 21.3 56.4 17.0 29.6 18.8 9.0 7.7 9.2 12.2 9.1 12.0 10.5 10.3 11.1 7.9 12.6 13.0 12.3 12.8 13.5 8.1 16.8 16.7 5.8 21.9 33.5 29.4 25.1 23.5 19.2 33.6 19.4 27.2 28.9 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA052186: , HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favourable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 13.9 14.5 13.0 14.8 21.5 34.8 17.0 28.9 25.7 15.8 14.4 26.6 14.1 11.1 18.3 13.4 17.4 15.9 11.7 12.3 13.5 13.3 14.0 11.2 15.5 18.5 15.4 15.2 20.7 19.0 34.7 25.3 15.2 20.3 16.3 14.6 19.3 15.7 14.9 16.9 24.5 16.4 17.2 13.1 19.2 16.1 15.2 18.1 29.9 17.4 10.4 24.8 16.6 14.5 12.3 7.8 12.8 7.4 8.7 8.6 3.0 16.2 21.3 23.6 11.0 15.1 13.1 13.4 12.9 14.9 19.7 19.7 18.5 14.1 26.9 8.2 17.3 20.0 28.9 18.2 25.0 20.6 13.2 23.6 14.3 22.4 14.0 32.6 22.5 17.6 14.8 22.1 15.9 17.5 16.4 14.4 14.9 17.5 23.4 13.3 18.0 18.1 22.0 17.9 9.1 14.6 30.1 17.3 16.6 20.3 15.8 11.2 11.1 15.8 20.5 16.4 12.6 9.6 15.3 16.4 19.5 26.9 6.6 12.1 16.3 12.8 4.8 12.1 7.7 5.0 8.6 5.8 6.8 7.5 3.3 12.3 7.4 6.4 11.0 8.7 7.4 7.8 5.7 3.0 13.0 21.5 28.9 25.7 13.5 13.3 15.4 15.2 20.3 18.1 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.7 4.7 13.5 16.7 3.8 19.2 8.7 7.3 8.6 9.7 14.2 12.0 10.1 17.4 6.2 5.1 14.2 20.5 13.4 11.3 12.4 15.7 22.9 9.0 19.8 3.8 14.5 16.8 8.1 6.2 12.4 11.0 10.7 13.8 15.2 9.0 20.7 11.6 23.3 19.0 12.0 25.3 9.2 20.3 6.0 6.1 7.9 4.5 8.1 14.5 8.0 9.9 13.4 3.7 7.8 9.3 6.8 3.8 9.2 16.2 34.0 7.4 15.2 9.9 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB026388: , HPA044341: , HPA064725: " "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 18.6 15.7 30.5 22.8 29.9 28.1 20.3 46.8 31.6 17.5 14.7 24.7 13.0 16.5 28.6 12.3 12.3 22.1 17.4 12.1 25.5 15.2 14.9 15.1 15.8 21.5 25.2 20.1 31.5 22.6 16.6 22.6 13.2 20.4 14.4 6.2 19.0 23.8 20.8 21.0 34.1 16.1 16.3 16.5 24.7 14.5 31.5 25.6 13.6 16.8 10.6 13.4 13.6 17.4 2.3 2.0 5.0 2.6 0.6 2.5 1.6 17.6 32.0 12.3 16.9 8.0 15.1 6.0 13.5 11.3 11.4 10.6 9.0 10.9 12.3 12.9 10.6 8.6 6.8 20.4 3.7 29.8 9.2 10.3 20.2 10.7 10.1 5.8 29.4 18.0 12.0 12.9 7.6 10.4 10.1 25.9 6.4 16.8 11.4 11.1 7.7 18.2 9.8 10.5 7.3 9.5 16.6 15.9 13.1 12.8 8.0 10.1 9.5 12.5 19.9 27.3 22.2 9.3 16.4 21.5 14.8 8.4 21.2 9.2 16.1 3.4 1.8 1.0 2.5 2.6 1.9 1.7 1.3 1.6 1.7 2.3 0.9 1.5 5.0 0.6 1.9 2.0 0.5 1.6 30.5 29.9 46.8 31.6 25.5 15.2 25.2 20.1 20.4 25.6 CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422632 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Supported "Microtubule ends,Cytosol" 7700 "Microtubule ends, Cytosol" "CAB004399: AB_671001, HPA026678: AB_1846954" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (6.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (2.51e-1)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (8.97e-2)" "unprognostic (3.26e-2)" "unprognostic (5.50e-2)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (2.52e-3)" 14.4 12.6 9.8 9.1 10.9 6.4 11.7 44.5 11.5 11.6 19.5 4.3 13.9 5.7 14.3 10.1 24.8 7.5 7.7 11.8 9.3 7.5 10.0 15.2 10.0 5.8 6.5 9.5 6.3 9.1 37.8 10.9 36.5 8.7 13.2 7.1 6.7 11.8 15.1 96.5 16.8 9.1 31.1 7.2 5.9 9.6 6.1 6.9 3.7 24.1 25.9 10.1 22.2 16.6 5.3 5.4 18.2 10.6 3.9 7.2 3.7 15.3 19.4 12.0 12.1 10.3 15.9 20.9 21.9 20.9 14.9 9.3 9.0 7.6 6.9 14.8 28.4 19.7 7.6 9.0 16.9 28.9 5.5 2.3 12.9 9.5 20.5 7.9 12.7 10.5 31.0 17.1 25.9 14.9 8.6 4.7 14.9 8.9 4.9 2.8 4.5 17.2 4.6 9.3 3.4 13.4 17.6 4.6 2.9 47.0 11.5 19.2 9.9 4.7 28.8 11.3 12.2 26.5 14.3 5.3 4.1 4.1 19.4 4.0 7.8 3.6 6.5 5.2 7.2 10.6 5.4 5.3 6.7 6.5 5.4 3.6 5.0 3.7 18.2 3.9 8.6 3.5 5.8 3.7 9.8 10.9 44.5 11.5 9.3 7.5 6.5 9.5 8.7 6.9 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" 51000000 "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: " "unprognostic (1.56e-1)" "prognostic unfavourable (7.35e-4)" "prognostic favourable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavourable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.02e-4)" 39.5 45.7 47.4 35.1 57.6 30.7 57.9 59.1 83.6 38.1 45.0 25.1 47.7 27.9 38.7 52.3 32.1 30.9 34.1 39.9 47.1 53.7 48.6 46.0 46.5 60.7 53.9 59.3 29.8 23.3 96.1 30.0 51.5 57.0 38.9 48.9 22.7 28.6 54.4 44.2 30.5 27.7 45.8 47.8 28.0 34.2 29.4 28.8 28.0 43.7 26.6 31.2 37.1 40.6 10.0 24.6 13.9 24.6 12.3 15.6 13.1 46.9 71.1 35.1 34.7 59.3 48.3 40.1 50.5 53.3 45.3 47.3 43.5 28.9 32.7 58.0 71.7 31.0 52.2 42.0 60.5 35.1 28.1 53.6 45.0 67.5 45.2 36.6 31.0 45.7 25.7 68.8 44.4 50.0 53.3 46.3 70.5 83.7 21.7 10.9 30.2 41.5 19.3 58.8 39.6 50.7 66.7 31.5 37.5 31.3 20.5 29.9 48.7 23.1 63.9 83.1 49.6 39.6 51.7 36.5 51.2 30.2 60.9 24.8 50.7 10.5 20.9 13.9 12.7 24.6 15.6 10.0 11.7 13.7 24.6 9.1 10.0 11.0 13.4 12.3 20.7 16.1 14.5 13.1 47.4 57.6 59.1 83.6 47.1 53.7 53.9 59.3 57.0 28.8 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291716 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.0" "Cell line enhanced" "Detected in many" "HMC-1: 34.3;K-562: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.3;neutrophil: 8.4" "Group enriched" "Detected in many" 15 "granulocytes: 8.4;monocytes: 3.3" "HPA075327, HPA075795" Enhanced Approved Vesicles Vesicles "HPA075327: , HPA075795: " "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 2.9 3.3 1.1 0.9 2.0 9.7 1.6 3.4 1.8 1.3 1.0 3.7 1.2 0.4 2.3 3.1 2.2 1.4 0.9 5.6 1.3 1.7 1.0 1.7 1.2 0.6 2.7 1.4 1.4 0.9 2.1 14.9 1.1 4.1 1.8 0.8 4.2 1.5 1.1 53.0 2.1 0.9 2.4 3.6 0.9 1.0 17.2 1.2 1.3 2.7 10.4 0.7 1.2 1.3 0.2 0.3 8.4 3.3 0.0 0.3 0.6 2.2 2.3 1.5 2.5 5.8 3.2 0.7 1.6 1.7 2.3 3.4 0.8 0.7 0.9 0.2 3.6 0.8 2.4 4.5 1.8 0.1 2.4 0.1 2.2 2.7 2.9 3.2 34.3 13.7 3.7 4.1 5.8 1.4 16.0 0.9 5.2 1.8 0.4 11.4 2.0 1.9 1.2 13.1 0.0 1.7 0.9 3.7 0.6 3.4 2.1 0.2 4.6 13.8 0.4 4.0 8.6 2.2 2.6 1.8 4.2 0.4 2.4 8.8 0.8 0.0 3.3 0.3 0.1 0.7 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.0 8.4 0.0 0.0 0.1 0.0 0.6 1.1 2.0 3.4 1.8 1.3 1.7 2.7 1.4 4.1 1.2 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405137-45513720 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 273.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 31.2;EFO-21: 70.3;NTERA-2: 39.1;TIME: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "neutrophil: 7.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.3" "Region enriched" "Detected in many" 6 "cerebellum: 24.8" "Low region specificity" "Detected in all" "CAB001961, HPA011025, HPA036104" Approved Approved "Golgi apparatus" "Secreted to extracellular matrix" 250000000 "Golgi apparatus" "CAB001961: , HPA011025: AB_1078551, HPA036104: " "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favourable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 25.5 14.4 2.2 12.7 13.0 5.6 17.7 3.4 8.5 40.4 12.7 26.0 19.6 12.6 22.2 72.5 12.0 18.8 25.3 18.5 3.5 5.3 36.2 273.2 11.9 7.6 35.5 3.5 43.3 21.8 2.6 17.8 16.5 20.8 13.9 2.3 17.3 8.8 20.2 8.1 23.1 10.6 33.4 31.9 14.5 7.1 11.0 23.6 2.3 16.0 12.0 6.7 28.7 18.2 0.4 0.4 7.3 0.4 0.0 1.2 0.2 2.5 19.1 4.8 4.3 8.9 7.4 1.0 18.4 31.2 8.8 2.4 11.9 6.8 0.5 70.3 18.2 8.6 1.0 1.1 1.7 0.2 5.3 11.0 0.3 16.2 8.6 0.4 1.1 8.7 0.7 0.8 1.0 27.1 11.1 0.1 3.2 4.4 0.4 1.1 39.1 7.1 0.5 3.0 1.1 29.7 0.4 5.4 4.1 1.8 2.0 5.8 1.8 3.0 41.3 0.2 2.8 0.1 4.3 0.1 0.2 0.3 0.0 0.9 7.6 1.0 0.4 1.5 0.1 0.4 0.2 0.4 0.4 0.0 0.1 0.1 1.2 0.6 7.3 0.0 0.3 0.4 0.0 0.2 2.2 13.0 3.4 8.5 3.5 5.3 35.5 3.5 20.8 23.6 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207603431 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavourable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 21.2 12.9 19.4 24.8 17.0 22.9 16.7 25.5 18.7 17.6 15.7 14.3 14.7 12.6 19.3 14.9 17.9 15.4 15.5 14.4 15.4 14.5 14.6 13.1 17.7 21.7 15.8 17.7 20.5 12.9 19.8 20.0 19.8 16.1 16.3 16.2 11.2 16.2 14.9 11.6 14.3 15.2 19.5 19.8 19.0 13.3 39.2 18.5 38.4 19.7 13.3 27.7 16.1 23.6 22.1 20.7 34.8 19.1 28.4 22.5 14.5 15.4 13.8 25.7 9.8 15.1 15.5 14.6 9.9 14.9 17.3 18.2 14.0 15.7 10.0 13.4 14.6 13.5 23.2 13.6 25.5 16.0 8.4 18.4 12.4 14.3 12.6 17.3 13.5 11.1 10.1 14.3 21.3 24.3 12.9 14.7 21.3 10.6 26.4 10.3 18.3 8.4 20.6 14.0 13.2 15.4 16.0 17.7 15.4 13.8 10.1 11.9 11.3 19.0 11.6 14.1 15.1 14.8 12.7 13.3 16.8 23.1 17.4 16.0 14.8 16.9 17.0 16.8 17.3 18.0 15.4 22.1 16.6 16.7 20.7 20.2 19.9 13.5 34.8 28.4 19.1 11.3 22.5 14.5 19.4 17.0 25.5 18.7 15.4 14.5 15.8 17.7 16.1 18.5 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683677-18782333 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022035 Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255" "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favourable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favourable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.6 7.7 26.0 7.4 38.8 3.2 3.8 40.7 30.1 5.0 4.4 6.5 4.3 6.5 6.8 5.6 3.1 10.5 5.5 5.6 17.7 7.8 6.6 4.5 5.7 6.3 6.4 18.1 6.7 10.0 8.4 11.3 6.4 6.0 7.0 2.6 5.1 8.8 9.4 12.4 5.5 6.2 4.3 4.8 8.1 8.0 7.5 10.2 1.9 7.4 1.1 3.7 4.6 3.5 4.1 3.8 1.8 3.4 1.1 3.0 1.3 4.3 8.0 5.8 9.3 5.4 4.6 16.5 4.8 3.2 4.6 4.5 5.4 5.7 6.1 10.2 4.6 4.7 1.7 3.0 1.1 2.7 13.9 5.1 7.1 8.8 5.2 7.0 14.5 7.4 2.9 4.0 1.2 2.6 4.0 5.6 2.6 16.0 4.5 8.1 7.5 11.8 7.2 2.5 6.7 2.9 7.8 10.7 9.6 5.4 5.2 5.8 5.8 4.3 4.6 5.3 8.1 9.6 5.5 3.8 3.0 4.0 6.1 7.6 4.0 1.5 3.4 1.8 1.7 1.3 1.8 2.3 2.7 3.0 3.0 4.1 2.3 1.8 1.7 1.1 1.9 3.8 1.8 1.3 26.0 38.8 40.7 30.1 17.7 7.8 6.4 18.1 6.0 10.2 CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529925-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 16.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: " "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" 22.3 14.0 13.7 17.0 20.9 11.4 26.6 15.0 16.2 21.2 22.2 27.5 15.3 8.9 23.9 14.5 15.1 19.4 21.5 17.2 14.0 9.7 10.7 11.7 19.2 21.7 24.1 10.9 45.9 13.9 17.1 9.6 20.2 15.7 18.2 11.7 17.4 19.9 22.0 16.1 15.8 13.7 31.8 20.3 13.1 14.2 15.3 23.6 12.8 22.7 9.2 18.1 24.0 29.6 5.3 2.1 16.0 2.5 3.3 6.6 3.0 4.7 7.9 5.4 8.8 11.7 8.7 24.7 6.1 8.9 9.6 9.1 6.5 4.8 0.1 4.4 12.6 8.0 8.6 5.3 7.6 8.2 10.0 12.1 39.3 3.0 13.3 3.1 20.7 9.7 8.5 7.9 10.7 6.9 6.4 2.8 7.1 5.5 1.3 4.5 1.9 3.7 4.1 8.6 0.2 3.4 10.1 9.9 8.8 17.8 5.9 9.9 5.9 5.9 8.5 10.7 7.9 9.9 7.0 3.7 5.0 3.6 4.4 6.3 5.1 16.0 2.5 1.4 3.7 0.8 4.2 3.1 4.5 4.0 1.6 5.3 6.6 4.1 0.5 3.3 0.3 2.1 4.2 3.0 13.7 20.9 15.0 16.2 14.0 9.7 24.1 10.9 15.7 23.6 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 266.5" "Cell line enhanced" "Detected in all" "MCF7: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" 13000 "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: " "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 71.2 31.4 33.5 25.8 33.2 37.9 42.1 29.6 35.4 39.0 64.7 29.6 35.9 29.5 46.4 38.9 58.8 30.3 29.4 64.2 33.2 31.7 37.4 39.5 34.2 31.4 41.6 31.4 43.9 37.2 50.3 38.4 38.8 44.4 52.6 32.9 32.0 43.2 42.0 266.5 33.8 46.5 88.3 42.4 32.2 39.9 41.5 35.1 39.6 55.7 73.9 31.9 75.4 45.5 43.9 59.0 57.9 65.2 48.1 62.3 80.5 60.6 21.4 38.1 38.0 43.5 56.6 53.3 53.6 40.1 36.1 29.4 31.3 18.4 47.8 45.3 51.1 25.8 42.2 41.6 52.7 58.4 28.8 46.9 39.0 27.7 38.5 34.8 28.0 41.0 45.3 43.2 57.1 41.3 47.5 31.4 44.1 222.4 46.7 22.2 72.6 28.9 35.0 118.0 22.5 28.7 47.8 47.1 31.3 52.5 43.8 40.6 22.5 55.7 49.7 42.7 58.9 56.0 58.8 48.0 52.2 53.6 55.2 39.6 130.2 46.4 57.7 57.9 40.9 60.8 55.5 43.9 52.2 49.7 59.0 34.7 62.3 52.3 40.9 48.1 65.2 23.0 56.7 80.5 33.5 33.2 29.6 35.4 33.2 31.7 41.6 31.4 44.4 35.1 CTCF ENSG00000102974 "CCCTC-binding factor" P49711 16 67562407-67639185 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm Nucleoplasm "CAB062550: , CAB068181: , CAB068182: , HPA004122: " "unprognostic (2.70e-1)" "unprognostic (4.21e-2)" "unprognostic (3.41e-2)" "unprognostic (4.70e-2)" "unprognostic (4.41e-2)" "unprognostic (2.70e-1)" "prognostic unfavourable (4.21e-4)" "unprognostic (1.71e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (1.99e-2)" "prognostic favourable (4.06e-4)" "unprognostic (3.47e-1)" "unprognostic (5.99e-2)" "unprognostic (4.58e-2)" "unprognostic (1.11e-2)" 19.1 17.5 22.3 35.0 24.3 32.2 20.2 31.6 26.6 23.0 19.4 20.5 21.0 16.5 24.2 15.4 23.1 21.7 20.3 17.6 21.8 16.7 19.5 19.5 17.2 27.9 22.3 21.0 24.6 21.2 42.4 21.8 23.5 17.9 19.4 23.2 14.3 19.9 24.9 29.4 25.2 21.4 22.0 20.2 26.1 18.5 14.8 22.9 68.8 20.7 16.2 35.5 22.6 26.7 10.1 7.9 9.6 6.2 4.9 7.2 1.9 10.9 16.9 22.5 8.9 10.3 8.8 18.3 10.5 11.1 15.5 14.9 13.8 11.4 34.4 8.5 9.1 14.2 21.7 11.8 17.6 12.2 14.3 20.8 9.6 15.8 7.0 23.6 20.0 7.1 14.3 11.6 13.0 11.8 18.2 14.4 12.8 21.5 49.5 9.0 19.5 11.3 36.2 18.5 18.9 9.5 15.9 19.3 13.4 19.0 11.1 9.3 13.7 14.7 11.2 13.4 13.9 10.2 11.5 12.6 15.8 50.1 7.7 14.2 14.3 9.4 3.4 4.9 6.7 3.4 6.3 7.9 7.2 5.4 3.1 10.1 5.9 6.7 9.6 4.9 6.2 7.9 5.4 1.9 22.3 24.3 31.6 26.6 21.8 16.7 22.3 21.0 17.9 22.9 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" 1000000 "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favourable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 52.9 54.5 38.8 33.5 45.9 46.3 70.5 78.8 59.3 71.7 49.6 57.3 34.2 48.7 79.2 42.5 46.3 49.8 45.0 42.1 38.6 41.5 46.9 53.2 53.6 31.6 37.0 47.0 84.2 38.6 59.2 44.0 82.6 41.5 50.8 50.1 75.9 53.9 49.7 31.2 44.7 70.4 66.5 39.4 41.0 37.3 29.0 39.3 40.1 62.3 44.5 36.6 46.9 54.2 10.1 13.5 7.5 14.5 11.1 13.5 4.8 22.6 30.2 63.7 35.6 34.4 28.2 48.9 25.6 36.4 42.8 42.5 20.8 32.4 18.6 23.4 45.2 17.0 46.1 73.9 45.9 17.2 31.4 30.0 40.1 74.3 25.7 17.0 14.4 41.0 33.5 51.1 31.1 37.6 21.2 11.6 47.4 23.0 11.9 9.2 58.0 23.5 9.0 41.5 12.4 26.5 70.9 15.2 25.8 42.4 21.6 113.7 35.4 35.4 48.4 32.2 24.7 20.6 37.5 7.2 11.2 19.8 33.0 21.5 53.7 4.3 8.1 6.9 11.2 14.5 13.5 9.6 10.5 12.1 13.5 10.1 10.7 10.8 7.5 11.1 13.7 11.7 12.6 4.8 38.8 45.9 78.8 59.3 38.6 41.5 37.0 47.0 41.5 39.3 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 12.5;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 8 "dendritic cells: 10.2;monocytes: 12.5" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" 15000 "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favourable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 39.7 19.9 15.1 20.4 17.0 3.2 31.4 15.0 20.5 28.8 41.9 25.7 49.2 37.5 32.7 32.7 76.3 22.9 28.8 18.2 15.6 10.3 30.6 31.2 34.0 11.6 14.4 12.8 23.3 50.4 41.9 34.5 49.8 16.4 29.7 39.8 34.4 46.4 39.1 11.8 48.7 82.0 22.8 17.2 25.9 39.4 27.8 14.7 7.1 38.4 34.9 45.6 32.3 38.9 1.4 10.2 0.4 12.5 0.4 0.5 2.3 37.4 28.1 25.1 16.8 13.6 18.6 35.6 17.2 19.4 15.6 14.9 21.8 41.6 0.7 30.4 21.3 49.2 20.2 26.1 20.0 0.4 6.6 9.3 11.0 24.6 14.1 2.0 14.7 20.5 31.6 19.7 20.2 47.4 14.0 0.4 17.2 12.1 0.7 3.5 17.9 15.1 0.7 21.2 0.8 23.3 40.0 2.3 11.2 24.3 33.3 25.4 35.0 2.5 40.1 15.0 12.9 14.7 9.7 1.3 0.8 1.1 14.0 1.2 26.4 0.0 6.9 0.2 0.2 12.5 0.5 1.0 0.1 0.4 10.2 1.4 0.2 0.3 0.4 0.4 11.9 3.1 0.2 2.3 15.1 17.0 15.0 20.5 15.6 10.3 14.4 12.8 16.4 14.7 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 128.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" 34000000 "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: " "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavourable (2.19e-6)" "prognostic unfavourable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 37.5 53.6 33.0 19.7 36.7 5.7 32.0 33.3 41.1 41.3 35.3 42.3 33.7 37.1 48.8 40.2 49.4 35.5 56.2 37.3 28.5 23.5 47.2 24.9 30.5 13.7 45.0 32.0 46.3 40.0 28.9 38.3 32.3 37.2 38.9 32.4 24.4 38.0 38.5 31.5 52.9 39.2 43.1 36.0 21.4 51.3 30.2 38.6 7.7 36.0 44.5 26.7 33.2 38.2 0.1 0.8 4.6 0.2 0.0 0.4 13.9 128.4 28.3 9.6 11.0 16.2 25.3 15.8 27.5 27.5 24.3 19.2 37.4 32.4 5.0 27.3 35.2 28.6 11.4 28.9 17.8 10.1 11.5 0.5 21.1 17.5 35.0 0.1 6.8 35.7 20.4 26.8 15.2 20.3 14.4 0.9 23.9 35.1 0.2 1.8 10.4 17.3 0.0 11.8 4.0 27.1 41.9 7.9 13.5 20.1 27.6 45.7 22.5 0.5 25.3 21.4 13.7 33.2 18.3 2.2 1.4 0.3 42.7 0.1 29.2 1.4 0.2 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 4.6 0.0 0.2 0.8 0.0 13.9 33.0 36.7 33.3 41.1 28.5 23.5 45.0 32.0 37.2 38.6 CUL1 ENSG00000055130 "Cullin 1" Q13616 7 148697914-148801036 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002676, HPA064584" Supported Supported Nucleoplasm,Nucleoli 190000 Nucleoplasm Nucleoli "CAB002676: , HPA064584: " "unprognostic (3.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-1)" "unprognostic (1.19e-1)" "unprognostic (5.06e-3)" "unprognostic (9.45e-2)" "unprognostic (1.41e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-2)" "unprognostic (3.65e-2)" "unprognostic (3.40e-2)" "unprognostic (2.84e-2)" "unprognostic (2.18e-2)" "unprognostic (3.88e-2)" "unprognostic (1.48e-1)" "unprognostic (2.40e-1)" "unprognostic (7.24e-3)" 26.0 20.9 21.2 20.4 22.4 22.3 27.5 27.5 26.2 23.9 25.8 19.5 22.5 16.7 30.2 23.7 22.7 21.2 18.7 25.7 21.1 21.8 16.9 35.2 20.5 26.5 21.7 16.7 25.0 17.9 24.9 30.7 32.0 21.0 23.9 18.8 22.7 19.6 25.0 58.9 20.5 21.2 37.7 26.3 21.9 22.4 65.6 23.7 16.9 24.5 24.6 24.5 26.1 28.8 16.8 24.1 13.4 17.1 22.1 20.8 16.1 30.7 23.9 23.5 36.3 18.5 20.8 29.8 25.4 30.0 25.7 24.5 25.4 21.5 42.2 20.4 25.1 20.8 33.5 23.7 30.3 27.5 28.5 24.9 16.9 24.6 21.7 28.2 23.7 17.0 23.3 18.8 19.1 28.0 38.4 32.6 28.0 29.4 24.5 32.3 44.0 22.9 29.8 20.7 40.6 21.1 22.5 33.8 24.8 29.6 35.3 20.0 11.6 22.4 21.5 18.4 6.4 37.2 29.2 30.6 21.2 41.8 37.4 31.5 27.1 13.4 15.2 12.0 16.1 17.1 18.6 16.8 16.7 18.6 24.1 14.4 20.8 16.7 2.1 22.1 14.5 5.5 15.9 16.1 21.2 22.4 27.5 26.2 21.1 21.8 21.7 16.7 21.0 23.7 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: " "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.1 2.9 3.3 3.7 5.3 7.7 3.0 13.6 19.9 14.2 8.4 2.4 4.3 10.6 4.9 13.2 3.6 3.9 8.2 21.1 46.4 6.0 5.3 5.1 1.9 10.6 5.2 24.9 8.4 6.7 17.1 17.9 5.7 2.2 9.2 19.8 1.3 5.1 7.6 3.5 4.8 4.6 6.8 10.1 4.6 3.2 4.3 3.3 11.5 3.9 3.3 3.9 6.6 6.4 24.3 5.5 8.5 5.5 24.3 23.1 11.8 17.8 5.9 5.1 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64499616-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043" Supported Enhanced Nucleoplasm 150000 Nucleoplasm "CAB005868: AB_446484, HPA020043: AB_1847572" "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favourable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 91.6 61.4 46.9 80.0 68.0 108.3 94.7 61.6 58.9 81.6 81.1 53.3 104.2 27.4 106.7 94.5 64.5 96.9 101.4 53.9 48.5 30.6 53.1 68.0 84.8 70.9 62.8 44.1 74.0 49.3 88.9 110.5 56.6 73.1 59.5 55.4 50.9 62.2 103.6 77.6 59.7 54.7 113.1 71.0 67.6 69.0 39.7 57.8 82.1 81.1 77.7 69.3 91.0 63.9 46.9 59.6 66.4 66.2 40.3 60.8 109.8 54.0 20.4 61.8 39.1 57.2 53.9 39.3 53.6 69.2 65.7 65.9 22.1 33.1 79.3 30.7 70.4 32.2 66.5 61.7 74.4 28.1 47.7 51.6 15.5 16.9 41.9 65.6 55.0 60.7 53.3 60.1 46.9 70.2 40.8 67.8 50.6 32.2 137.1 19.1 36.0 63.0 85.9 65.2 55.8 40.3 25.9 43.4 72.9 52.0 50.5 65.3 47.3 36.9 49.3 40.0 44.7 43.1 55.5 37.9 74.6 140.0 42.4 32.3 47.1 66.4 62.5 66.4 53.7 56.9 60.8 46.9 42.9 51.7 59.6 46.8 44.5 43.1 37.8 40.3 66.2 37.0 50.2 109.8 46.9 68.0 61.6 58.9 48.5 30.6 62.8 44.1 73.1 57.8 DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839369-182887751 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050" Supported Supported Nucleoplasm 97000 Nucleoplasm "CAB011819: AB_777725, HPA028050: AB_10603564" "unprognostic (8.14e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (7.40e-2)" "prognostic unfavourable (3.17e-4)" "unprognostic (9.98e-2)" "prognostic unfavourable (6.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.88e-2)" "unprognostic (5.53e-2)" "unprognostic (7.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-1)" 30.2 25.9 25.7 28.5 28.6 68.9 32.9 42.5 33.1 31.9 24.5 23.3 25.2 19.8 38.2 24.2 27.7 30.6 19.7 22.9 24.4 22.6 36.2 31.4 27.8 32.0 34.2 23.1 37.5 24.9 51.8 35.8 28.5 28.0 25.7 30.1 21.1 28.2 29.4 27.6 26.6 27.0 31.6 25.3 32.8 26.5 29.4 37.4 68.3 30.1 31.6 41.2 32.4 31.9 16.8 22.9 12.0 17.4 14.7 21.9 15.0 35.1 34.5 49.5 27.2 25.9 20.1 48.9 31.2 28.6 45.4 30.8 38.5 27.2 56.5 30.5 28.0 30.5 75.1 33.8 50.8 22.9 37.3 37.6 28.2 26.0 14.6 54.4 25.8 17.9 17.0 44.5 12.1 35.4 59.0 20.3 36.3 30.9 55.0 13.4 62.7 21.3 50.2 46.2 32.3 29.3 40.9 35.7 41.0 44.2 28.0 18.2 32.7 30.8 27.6 28.2 31.5 28.6 42.2 21.3 34.8 67.1 17.7 29.9 38.2 5.6 16.0 12.0 19.2 17.4 21.9 16.8 16.8 17.6 22.9 14.6 18.4 19.9 6.5 14.7 14.3 11.1 15.4 15.0 25.7 28.6 42.5 33.1 24.4 22.6 34.2 23.1 28.0 37.4 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol Cytosol "CAB068185: , HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 23.2 12.5 18.4 22.4 33.3 20.5 23.2 28.5 29.9 19.0 18.1 31.4 22.4 13.0 20.8 20.6 23.4 18.5 16.2 15.3 22.0 14.1 19.5 23.6 22.4 20.3 29.7 19.6 23.8 19.8 26.9 30.9 29.9 23.2 20.3 19.7 14.5 19.5 18.9 28.0 20.7 17.3 19.0 26.8 20.7 17.1 20.6 32.0 17.0 23.8 14.7 20.3 20.7 24.1 2.5 1.8 10.7 7.2 1.2 3.3 1.0 12.8 13.4 25.1 9.3 6.5 9.8 19.9 10.6 6.4 6.8 8.2 17.0 9.9 14.5 11.5 9.8 15.2 19.9 10.0 14.2 22.5 8.9 21.9 7.4 12.2 6.6 13.4 13.5 9.1 8.3 9.1 13.9 10.1 9.2 12.9 11.4 18.0 15.0 8.9 7.1 6.6 12.0 20.5 8.0 9.0 20.5 20.8 11.8 10.7 11.0 12.0 12.4 9.9 10.0 5.2 10.3 10.1 11.9 14.8 21.1 20.6 5.4 10.9 9.3 3.1 3.0 1.2 1.6 3.1 3.3 1.9 1.5 1.2 1.8 2.5 1.5 1.3 10.7 1.2 7.2 1.6 1.6 1.0 18.4 33.3 28.5 29.9 22.0 14.1 29.7 19.6 23.2 32.0 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339441 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 16.1;Hep G2: 14.7;RH-30: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.6;naive B-cell: 4.9;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 18 "B-cells: 4.9;dendritic cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 19.8 11.8 12.5 11.6 11.1 0.7 11.8 15.6 11.6 18.9 25.6 6.8 30.3 4.5 22.2 10.0 13.1 12.5 22.3 27.5 10.0 7.6 4.4 36.2 5.9 3.7 8.5 9.8 11.7 34.5 4.9 4.1 10.3 7.8 14.5 6.8 10.7 19.7 31.6 57.7 8.5 7.4 48.2 6.1 1.9 11.9 4.6 7.4 0.0 6.2 34.5 4.7 32.6 7.9 4.9 1.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 16.1 0.0 0.1 0.1 4.8 3.2 0.3 1.7 1.9 8.0 0.0 0.2 0.0 8.8 5.4 6.4 8.2 2.7 4.7 5.1 0.2 7.3 14.7 9.3 0.0 1.5 2.1 6.0 3.0 11.3 4.3 0.6 0.1 4.6 0.3 2.5 0.0 8.1 7.4 0.1 20.3 0.0 0.1 1.3 0.3 4.5 0.0 1.2 2.3 1.1 0.0 0.5 0.1 0.0 0.2 3.3 0.1 6.6 0.3 0.4 0.0 8.8 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.1 0.0 0.7 4.9 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 12.5 11.1 15.6 11.6 10.0 7.6 8.5 9.8 7.8 7.4 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 25.5;REH: 25.1;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavourable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavourable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 7.8 12.4 13.7 12.7 15.5 10.8 8.6 21.6 20.1 9.0 12.7 14.5 7.6 9.1 13.0 12.2 8.0 9.6 8.9 8.2 12.3 6.7 9.4 6.9 9.5 13.6 15.3 10.1 18.3 12.1 6.3 12.6 20.8 10.7 9.3 9.2 12.0 8.5 9.2 29.1 6.6 11.4 11.3 7.9 17.5 11.6 6.6 15.2 20.8 9.1 10.5 11.8 9.8 8.4 3.0 4.1 4.9 4.1 8.7 8.3 2.3 1.0 3.5 14.7 3.6 1.6 1.2 19.4 1.0 0.9 2.0 1.6 8.7 5.7 0.0 2.2 1.9 0.9 1.6 2.2 1.2 3.6 2.5 6.3 5.3 10.4 3.8 1.3 4.1 3.6 1.1 2.6 0.9 8.2 7.3 1.3 1.5 8.4 13.8 14.9 25.5 1.9 25.1 16.2 2.1 1.2 1.5 8.8 31.0 1.2 8.4 2.6 0.9 6.7 2.8 2.5 3.2 0.6 1.3 3.1 2.2 8.5 0.9 3.8 2.6 4.7 1.8 3.1 5.2 3.0 7.0 2.3 3.4 4.9 2.0 3.0 8.3 6.6 4.9 8.7 4.1 4.1 2.8 2.3 13.7 15.5 21.6 20.1 12.3 6.7 15.3 10.1 10.7 15.2 DOCK2 KIAA0209 ENSG00000134516 "Dedicator of cytokinesis 2" Q92608 5 169637247-170083382 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.0;bone marrow: 29.8;lymphoid tissue: 50.3" "Cell line enhanced" "Detected in some" "Daudi: 31.9;HDLM-2: 40.1;HL-60: 31.8;HMC-1: 37.0;MOLT-4: 24.2;U-698: 28.2;U-937: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036469 Enhanced "HPA036469: " "unprognostic (3.45e-2)" "unprognostic (1.84e-2)" "unprognostic (3.90e-3)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (5.92e-3)" "unprognostic (3.47e-1)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (2.03e-3)" "unprognostic (1.47e-1)" "unprognostic (2.22e-2)" "unprognostic (6.95e-2)" "unprognostic (7.24e-2)" 7.3 3.1 2.9 30.7 4.8 29.8 4.1 1.0 2.7 2.2 3.5 5.8 1.2 2.6 2.9 2.7 2.4 2.9 4.9 2.7 3.4 2.5 3.1 2.9 12.6 22.6 4.8 1.3 1.9 1.9 0.7 2.2 3.8 4.1 3.3 4.5 2.6 6.6 1.2 1.3 2.0 13.7 3.6 8.5 28.0 3.6 1.8 3.7 50.3 2.8 1.7 31.5 6.2 2.5 6.4 14.0 12.7 31.0 6.6 6.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 3.2 0.0 0.0 31.9 0.6 2.5 0.0 0.0 0.0 4.0 40.1 0.0 17.7 0.3 0.0 0.0 31.8 37.0 0.0 0.0 0.7 0.0 0.0 0.3 16.0 0.8 0.0 24.2 8.2 0.0 0.0 15.1 0.5 12.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.1 0.3 1.0 0.4 0.7 5.0 7.8 28.2 0.6 22.1 0.0 6.2 12.7 10.0 6.4 23.0 6.6 6.4 5.9 6.3 14.0 5.3 4.3 5.0 12.7 6.6 31.0 4.8 5.3 9.4 2.9 4.8 1.0 2.7 3.4 2.5 4.8 1.3 4.1 3.7 EEF1A1 "EE1A1, EEF1A, EF1A, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73515750-73523797 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol Cytosol "HPA051759: , HPA053862: , HPA056990: " "unprognostic (6.47e-2)" "unprognostic (7.86e-3)" "unprognostic (2.53e-2)" "unprognostic (9.64e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.41e-1)" "unprognostic (3.47e-1)" "unprognostic (8.61e-2)" "unprognostic (1.65e-1)" "unprognostic (8.00e-2)" "unprognostic (2.04e-1)" "unprognostic (7.73e-2)" 134.1 124.1 80.2 136.0 75.6 140.9 182.0 103.3 106.2 149.6 133.3 94.9 93.7 81.7 152.0 127.3 136.4 143.1 102.4 88.2 71.5 58.0 130.9 123.1 169.6 135.6 74.3 93.2 240.8 227.6 106.3 111.2 89.1 79.7 115.0 114.7 105.0 133.3 123.6 51.3 139.8 101.6 121.6 108.6 111.3 121.5 129.9 71.6 125.1 132.4 143.1 169.7 151.1 134.8 258.9 209.7 54.6 187.6 184.6 366.8 517.5 111.1 141.0 200.2 273.4 410.7 679.5 159.4 166.6 430.1 213.7 205.1 218.7 153.9 454.1 222.8 281.5 118.0 244.5 318.4 206.0 79.2 153.0 169.5 115.0 243.6 356.6 315.0 185.1 587.0 541.5 157.3 530.9 289.4 313.2 143.7 258.2 148.2 134.8 330.2 214.2 98.0 268.8 337.3 509.0 274.5 235.6 164.3 182.4 83.5 196.4 329.6 133.5 509.2 240.4 91.3 130.0 67.6 189.1 161.4 143.4 106.6 94.8 261.3 143.4 54.6 187.6 20.8 198.7 165.4 366.8 258.9 288.8 250.9 209.7 199.5 323.8 277.8 17.0 184.6 169.0 161.7 202.9 517.5 80.2 75.6 103.3 106.2 71.5 58.0 74.3 93.2 79.7 71.6 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell line enriched" "Detected in many" 12 "A-431: 337.7" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: , CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavourable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 337.7 4.3 1.1 1.5 6.9 4.3 1.1 3.3 4.5 2.0 1.6 0.8 3.7 0.2 0.8 2.8 13.5 0.0 14.9 2.5 0.1 0.2 0.0 1.8 0.2 1.8 0.0 0.0 2.1 13.7 5.2 27.9 0.2 0.0 0.0 4.4 0.2 0.0 0.0 0.3 2.2 0.0 0.6 0.0 2.5 3.6 0.0 1.3 2.8 3.4 0.6 0.3 0.7 1.0 1.9 0.5 14.6 3.1 0.0 0.3 0.1 2.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789900 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol 1000000 Cytosol "CAB011690: AB_732123, HPA068286: " "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 34.6 66.1 61.2 27.7 79.9 1.9 53.5 121.1 111.5 65.1 52.1 26.5 30.1 30.3 73.1 45.5 44.5 73.9 45.1 83.7 58.4 71.9 63.9 43.5 33.7 36.1 48.9 61.7 142.0 59.0 30.9 84.1 47.3 69.6 57.9 40.1 31.8 43.7 62.8 126.7 19.8 35.6 57.1 41.9 32.5 39.0 32.9 39.5 23.9 67.8 36.4 35.4 61.1 51.7 55.1 19.3 39.4 24.8 33.0 63.4 51.3 10.5 5.3 22.3 3.6 85.9 81.0 6.8 19.0 17.2 20.2 26.6 19.6 3.8 23.6 106.5 27.3 17.8 32.7 8.0 35.6 22.0 17.2 38.0 7.1 26.3 33.7 8.0 26.7 54.2 38.5 5.8 48.6 35.8 12.8 39.8 65.6 1.8 12.7 3.9 22.1 25.5 16.3 15.8 14.3 40.0 12.9 43.9 8.8 30.9 21.3 40.4 33.2 29.3 26.1 16.0 8.0 15.4 11.6 31.7 44.8 10.8 11.0 8.4 7.5 39.4 16.0 18.5 28.5 18.2 45.3 55.1 41.9 34.8 19.3 46.1 63.4 50.2 11.0 33.0 24.8 17.4 38.6 51.3 61.2 79.9 121.1 111.5 58.4 71.9 48.9 61.7 69.6 39.5 ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017188 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 100.8" "Cell line enhanced" "Detected in some" "A549: 40.4;CAPAN-2: 57.6;RT4: 41.4;SK-BR-3: 79.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA003316: AB_1078757, HPA003479: AB_1078756" "unprognostic (9.90e-3)" "unprognostic (1.72e-1)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (5.05e-3)" "unprognostic (7.67e-3)" "unprognostic (7.07e-2)" "unprognostic (9.92e-3)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-3)" 0.3 0.1 0.1 16.0 0.2 0.0 34.0 0.2 0.2 13.2 80.7 0.2 12.5 34.4 3.8 8.9 59.3 8.6 67.7 1.1 0.1 0.1 38.1 33.3 24.6 0.1 0.1 0.1 5.8 38.4 1.1 1.7 16.7 0.3 39.9 31.3 0.7 37.9 11.3 0.7 3.5 100.8 9.5 0.3 0.2 29.9 1.9 0.1 0.6 5.7 25.5 43.5 44.7 22.7 0.3 0.8 2.0 0.3 0.2 0.3 0.0 10.5 40.4 0.0 0.0 0.0 0.0 12.6 0.0 1.5 0.0 0.0 9.0 57.6 0.0 4.7 0.0 10.5 0.0 0.0 0.0 1.2 0.0 0.0 7.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.1 0.6 3.4 0.0 0.0 0.5 15.3 41.4 0.0 0.0 0.4 79.9 0.0 5.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.8 0.3 0.2 0.1 2.0 0.2 0.3 0.2 0.0 0.0 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.3 0.1 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41091786-41180079 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favourable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 16.8 14.8 19.1 13.9 15.5 45.3 14.5 33.0 20.6 14.8 16.8 15.6 18.9 11.1 18.1 11.6 16.8 15.7 16.5 10.7 16.6 8.3 11.5 12.2 14.1 12.9 16.9 12.7 20.2 15.7 26.4 14.5 27.7 13.8 13.2 12.2 12.3 15.3 17.9 19.5 18.2 17.4 13.8 12.7 15.9 14.7 20.6 18.6 29.3 16.9 10.9 14.1 18.7 22.5 4.3 4.4 9.8 3.9 5.7 3.9 2.3 15.5 11.2 19.0 11.8 12.1 13.0 17.0 7.5 10.9 11.3 10.8 14.2 5.7 16.2 6.6 14.8 12.5 27.4 10.3 12.5 15.8 18.2 12.2 12.8 11.1 13.7 28.8 13.8 12.7 10.8 16.3 13.6 12.5 12.8 22.3 8.9 5.7 8.3 9.0 13.7 7.8 17.1 8.9 10.1 10.7 20.7 6.1 6.4 26.6 13.6 13.0 9.6 16.8 16.1 11.3 13.7 8.0 10.6 15.3 7.2 25.3 8.3 8.9 10.7 5.0 3.2 3.0 3.7 3.9 3.2 4.3 3.6 3.9 4.4 2.9 3.1 2.6 9.8 5.7 2.1 3.0 2.6 2.3 19.1 15.5 33.0 20.6 16.6 8.3 16.9 12.7 13.8 18.6 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in many" 27 "SK-BR-3: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.8" "Lineage enriched" "Detected in many" 4 "T-cells: 8.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Plasma membrane,Cytosol" 430000 "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: , HPA001060: , HPA001338: , HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavourable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favourable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 5.8 2.4 5.2 10.4 7.0 0.1 20.1 4.2 7.0 19.1 46.5 9.1 55.2 21.6 14.9 18.7 40.9 22.7 26.6 24.8 6.3 3.1 37.5 21.5 17.6 3.7 5.1 5.6 19.3 16.2 27.7 8.1 60.8 7.5 23.6 16.6 15.9 28.7 58.1 8.9 35.3 47.2 10.9 4.5 4.0 17.1 6.5 3.7 2.8 35.7 20.8 22.9 19.7 20.3 1.3 0.3 2.1 0.4 0.9 8.8 2.2 3.1 3.8 4.2 2.7 5.1 3.6 5.7 2.2 3.7 4.9 4.2 2.8 8.6 0.2 4.6 5.1 9.8 0.2 5.1 2.3 0.4 3.2 0.1 3.0 4.5 3.0 0.0 0.0 3.5 4.8 3.0 1.8 2.0 0.4 0.1 3.6 4.8 0.5 0.2 7.6 0.9 0.3 1.7 0.4 5.0 9.8 0.8 0.2 4.2 263.9 1.3 7.4 0.1 0.2 2.5 3.3 3.2 1.4 0.4 0.2 0.2 0.2 0.0 8.2 1.6 0.4 0.8 8.8 0.3 0.7 0.9 0.5 2.5 0.3 1.3 1.0 2.5 2.1 0.9 0.2 0.2 0.4 2.2 5.2 7.0 4.2 7.0 6.3 3.1 5.1 5.6 7.5 3.7 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: , HPA069266: " "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favourable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 7.4 15.6 11.4 10.6 17.7 6.7 7.1 9.5 23.8 9.4 8.1 11.7 7.8 7.9 11.7 6.0 6.7 10.0 10.1 7.9 9.4 9.1 8.7 13.2 6.5 9.9 8.2 10.5 9.5 13.1 12.9 10.9 7.2 14.0 8.2 6.4 12.5 9.5 11.8 15.9 10.7 7.1 11.2 5.3 9.7 8.3 17.2 7.8 10.8 10.2 5.1 8.3 9.3 6.6 7.8 17.2 5.0 13.9 11.3 9.8 8.7 12.3 6.0 12.6 17.7 7.5 8.9 6.7 17.6 12.1 22.8 17.5 14.0 8.5 4.4 10.1 17.1 6.4 8.8 14.8 8.7 10.6 14.5 7.5 11.5 14.7 15.9 11.9 13.3 10.2 2.3 26.0 14.8 13.2 18.2 5.0 15.7 6.0 7.0 7.9 5.8 10.6 13.5 8.9 3.7 6.5 10.9 7.4 8.0 15.6 11.1 6.2 10.5 15.8 17.1 21.8 11.9 9.2 39.1 11.6 6.7 6.4 6.4 7.3 9.6 0.0 13.3 5.0 7.7 13.9 9.8 7.8 7.4 7.4 17.2 5.8 7.1 7.4 0.4 11.3 10.9 8.3 7.4 8.7 11.4 17.7 9.5 23.8 9.4 9.1 8.2 10.5 14.0 7.8 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 64.5;endometrium 1: 68.9" "Group enriched" "Detected in some" 9 "MCF7: 24.3;T-47d: 31.5" "Group enriched" "Detected in many" 9 "breast cancer: 40.2;endometrial cancer: 24.3;ovarian cancer: 8.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: , HPA000449: AB_1078753, HPA000450: AB_1078754" "unprognostic (8.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.43e-2)" "prognostic favourable (5.47e-7)" "unprognostic (4.79e-1)" "unprognostic (2.43e-3)" "unprognostic (4.10e-5)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (7.35e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-2)" "unprognostic (7.91e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" 3.0 0.9 0.5 1.6 0.5 0.2 16.2 0.8 0.4 64.5 1.5 0.2 2.2 0.1 68.9 27.7 1.1 26.7 1.9 1.1 0.5 0.8 1.5 6.6 3.6 1.6 0.4 0.1 14.2 0.4 0.0 9.3 0.9 0.6 3.6 0.1 2.6 1.6 4.1 2.0 0.6 0.5 20.8 0.4 1.6 0.3 1.9 0.4 1.9 1.3 2.2 2.5 3.8 23.7 0.6 1.0 0.0 0.8 0.3 2.5 1.0 0.3 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.6 0.0 24.3 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 1.8 0.0 0.0 0.0 0.3 0.0 31.5 0.0 0.0 0.1 0.1 0.3 0.0 2.9 0.5 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.3 0.2 1.0 0.6 1.3 0.4 1.0 0.4 2.5 0.9 0.0 0.3 0.0 0.0 0.3 1.0 0.5 0.5 0.8 0.4 0.5 0.8 0.4 0.1 0.6 0.4 EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Enhanced Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavourable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavourable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" 35.3 43.2 45.3 41.3 51.3 67.5 32.1 58.2 48.6 32.4 39.8 43.2 31.3 41.0 45.1 38.5 40.8 37.6 25.9 40.7 40.1 32.8 33.0 48.5 33.4 50.5 32.7 49.9 38.4 32.0 47.2 44.3 34.0 41.7 35.0 39.9 41.5 32.3 38.2 52.8 34.8 36.6 40.5 33.8 44.1 34.5 85.6 32.5 39.9 32.5 30.9 55.4 36.4 34.5 52.0 65.8 50.6 81.1 58.4 67.8 76.1 56.4 44.0 60.5 47.0 30.9 25.6 41.6 34.4 55.0 57.1 49.0 50.1 29.3 77.2 21.8 52.7 44.4 86.2 70.4 58.8 52.5 61.5 58.3 39.0 47.9 46.2 89.6 41.7 39.1 29.7 47.6 77.3 44.1 43.6 34.9 42.2 56.7 90.0 34.4 42.5 33.5 63.2 58.3 46.6 52.5 60.0 49.6 47.4 42.8 50.2 37.1 32.2 48.8 45.0 34.9 38.8 21.9 49.9 45.4 36.4 71.6 33.2 39.9 42.4 48.4 57.9 50.6 60.2 81.1 60.7 50.4 56.6 59.6 65.8 52.0 55.8 53.6 43.3 58.4 78.6 35.3 67.8 76.1 45.3 51.3 58.2 48.6 40.1 32.8 32.7 49.9 41.7 32.5 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.5;lymphoid tissue: 44.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009589 Enhanced Supported Nucleoplasm Nucleoplasm "CAB009589: " "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavourable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavourable (8.18e-12)" "prognostic favourable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 2.0 1.7 1.8 10.6 1.6 25.5 1.4 4.9 2.7 2.6 4.8 1.1 0.1 3.8 1.7 2.8 11.0 0.9 3.0 0.9 0.8 0.6 1.7 3.3 2.3 12.6 1.3 0.3 2.2 3.8 0.6 1.7 3.4 1.4 1.4 5.1 1.8 3.2 1.6 3.7 6.4 4.8 1.5 1.2 5.8 2.7 19.6 1.3 44.1 0.9 5.5 12.4 2.6 3.5 1.5 4.7 1.3 3.9 8.5 10.3 1.7 16.9 7.9 27.1 18.0 0.8 1.4 14.8 13.2 5.3 10.9 11.0 11.9 19.6 29.9 6.4 4.9 10.4 13.9 4.5 13.9 42.8 13.9 12.7 9.8 9.2 2.2 28.4 10.5 1.2 2.6 8.1 4.3 6.4 27.1 19.9 9.7 19.2 55.1 23.7 21.5 10.7 34.1 15.2 18.5 5.0 8.1 25.9 16.5 16.6 12.6 4.3 9.2 12.2 3.9 11.6 5.4 23.1 23.6 17.9 19.4 30.1 10.6 19.4 22.7 0.5 2.2 1.3 1.7 1.5 1.3 1.5 3.4 2.9 4.7 0.8 1.9 1.2 0.2 8.5 3.9 1.0 10.3 1.7 1.8 1.6 4.9 2.7 0.8 0.6 1.3 0.3 1.4 1.3 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "Fanconi anemia complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;testis: 28.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm Nucleoplasm "HPA063236: " "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 2.1 2.0 2.2 16.5 3.7 17.1 1.7 5.7 6.6 1.7 5.1 1.1 0.6 5.0 1.7 3.1 6.6 1.9 1.6 1.7 1.8 1.4 2.1 5.8 3.3 11.1 1.3 2.7 1.6 1.8 2.3 1.9 11.2 2.4 1.7 6.3 1.5 2.2 0.5 0.7 5.0 5.4 2.0 1.6 6.9 3.5 28.8 0.8 20.6 1.7 4.6 17.6 2.9 2.5 7.4 6.5 9.9 9.2 7.5 9.5 4.2 9.2 14.2 17.0 14.9 1.1 2.2 13.0 11.5 6.3 19.5 8.2 12.4 15.4 22.7 5.4 3.9 14.2 11.4 8.6 20.6 5.3 19.2 6.7 18.2 25.4 0.7 6.8 7.4 0.7 0.9 15.8 5.0 6.1 16.1 7.0 10.1 21.4 13.6 29.5 11.0 8.9 24.8 13.7 4.1 4.8 8.7 15.3 8.3 17.2 5.1 2.2 9.3 12.3 4.5 15.7 16.5 8.7 12.0 6.3 7.3 22.6 7.4 15.3 14.8 2.6 7.9 9.9 4.7 8.8 3.3 7.4 2.8 4.1 6.5 5.5 0.7 3.0 9.8 7.5 9.2 0.4 9.5 4.2 2.2 3.7 5.7 6.6 1.8 1.4 1.3 2.7 2.4 0.8 FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "placenta: 175.9" "Cell line enhanced" "Detected in many" "HHSteC: 37.3;HSkMC: 26.6;hTERT-HME1: 58.9;HUVEC TERT2: 33.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "classical monocyte: 2.5;non-classical monocyte: 5.0" "Lineage enriched" "Detected in many" 5 "monocytes: 5.0" "Region enhanced" "Detected in single" "olfactory region: 2.6" "Low region specificity" "Detected in some" "HPA012853, CAB026401" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" 4600000 Cytosol Nucleoplasm "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (7.41e-5)" 0.3 7.9 0.3 1.0 0.3 1.6 0.1 0.2 0.3 1.5 0.7 0.4 1.0 0.2 2.9 0.6 1.1 0.6 0.2 6.7 0.2 0.5 0.2 0.2 0.2 1.3 0.2 0.4 0.9 0.1 0.0 1.3 175.9 0.4 1.0 0.8 6.2 0.4 0.9 0.2 0.3 0.5 0.8 0.4 0.6 0.5 4.6 0.2 0.3 0.9 0.4 0.7 0.4 1.2 0.0 1.1 0.6 5.0 0.0 0.0 0.4 0.0 4.4 16.1 0.0 2.6 4.6 3.3 17.6 0.0 15.6 11.7 0.0 0.0 0.0 0.0 23.5 2.6 10.4 2.6 14.7 0.0 4.2 0.0 7.4 0.0 37.3 2.3 0.0 26.6 1.4 6.6 58.9 33.1 0.0 0.0 9.6 0.0 0.0 0.8 6.9 5.3 5.1 5.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 4.9 0.0 6.3 12.0 17.9 0.0 0.0 0.0 0.0 1.8 0.0 6.6 0.0 2.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 5.0 0.0 0.0 0.4 0.3 0.3 0.2 0.3 0.2 0.5 0.2 0.4 0.4 0.2 FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47905793 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm Nucleoplasm "HPA002690: AB_1848448" "unprognostic (1.18e-1)" "unprognostic (8.65e-3)" "unprognostic (3.93e-2)" "unprognostic (2.05e-2)" "unprognostic (7.92e-2)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (9.82e-2)" "unprognostic (5.77e-2)" "unprognostic (2.33e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" 18.0 13.8 18.6 15.7 18.8 17.5 26.1 42.2 31.7 21.3 15.3 12.7 15.1 10.4 28.9 16.8 14.5 16.3 15.0 14.1 16.9 13.6 14.3 17.0 22.3 15.0 17.4 21.7 28.9 12.4 25.2 14.4 14.5 19.7 15.3 13.3 12.0 15.6 16.5 22.9 14.5 13.5 19.9 16.4 14.5 13.3 25.1 16.0 14.6 17.3 9.8 17.2 19.3 21.9 4.7 4.3 8.2 2.7 4.8 6.6 2.0 25.5 13.3 32.0 27.2 22.5 21.2 19.1 17.9 24.7 16.8 16.6 11.2 13.1 16.6 23.5 25.2 12.8 21.8 18.9 24.8 11.0 10.9 15.4 11.0 17.8 21.5 16.0 16.4 20.6 21.4 14.9 25.3 21.5 15.0 17.2 20.5 12.3 15.4 15.7 19.5 13.2 20.1 29.7 12.3 24.0 20.9 22.6 26.7 17.0 15.9 26.2 7.4 13.7 23.1 20.8 19.2 14.0 19.6 14.9 7.7 30.2 14.1 15.1 21.2 8.2 2.3 4.3 3.8 2.7 3.8 4.7 3.4 4.1 3.1 3.6 6.6 4.1 4.1 4.8 2.4 4.3 3.6 2.0 18.6 18.8 42.2 31.7 16.9 13.6 17.4 21.7 19.7 16.0 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536063 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 60.1;skin 1: 45.0" "Cell line enhanced" "Detected in all" "U-266/70: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavourable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 9.2 6.8 27.0 8.9 27.9 11.1 9.8 27.2 60.1 5.5 6.1 3.6 3.8 4.9 6.0 18.3 9.8 10.6 6.3 10.9 21.4 10.1 4.1 7.3 6.9 9.8 9.1 40.5 6.4 8.0 6.4 7.3 6.2 37.2 5.1 6.9 2.8 7.6 5.3 15.8 45.0 6.5 6.1 6.4 10.1 8.0 13.7 5.7 6.5 6.8 10.6 12.3 7.9 6.5 2.9 2.2 16.6 3.4 7.8 5.0 1.3 4.9 3.9 10.2 7.4 7.1 5.1 8.4 7.1 6.5 4.4 4.2 7.9 6.3 12.7 2.0 6.8 2.9 8.7 16.0 6.2 7.2 4.1 5.9 4.8 5.6 7.2 14.4 5.4 8.1 25.3 7.6 12.9 7.7 9.3 13.6 5.5 6.9 16.5 5.7 5.0 3.1 16.6 4.3 2.5 5.4 8.5 6.5 5.6 4.5 6.2 3.9 3.4 6.8 8.1 6.0 6.8 3.1 4.0 37.4 21.3 12.4 4.8 4.7 4.3 16.6 3.1 1.7 5.0 3.4 3.3 2.9 3.7 3.2 1.8 2.4 3.9 3.2 5.5 7.8 2.5 2.2 3.3 1.3 27.0 27.9 27.2 60.1 21.4 10.1 9.1 40.5 37.2 5.7 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 60.8;lymphoid tissue: 49.7" "Cell line enhanced" "Detected in many" "HEL: 20.9;HL-60: 18.6;HMC-1: 39.8;NB-4: 24.4;THP-1: 36.6;U-937: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Group enriched" "Detected in many" 4 "dendritic cells: 32.6;granulocytes: 60.8;monocytes: 30.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavourable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 14.9 3.4 4.8 9.7 4.1 38.3 12.7 2.4 5.7 6.8 5.4 3.2 4.7 3.0 7.4 5.6 4.9 7.6 7.3 7.9 4.2 2.2 5.2 11.8 12.7 23.3 3.7 0.9 6.4 3.7 1.8 2.7 8.1 7.2 7.7 2.4 5.3 33.8 6.3 3.4 3.5 5.2 5.4 6.9 49.7 4.3 3.2 4.7 3.1 7.2 4.1 4.5 7.2 9.4 1.1 32.6 60.8 30.5 9.3 0.1 13.8 0.1 0.2 0.3 3.5 1.0 3.1 6.0 0.9 0.0 1.7 1.0 0.8 0.0 2.2 0.1 2.0 0.5 0.6 0.1 0.5 1.1 0.3 20.9 0.0 3.7 2.0 18.6 39.8 3.0 0.0 2.6 0.0 10.5 0.6 0.0 0.0 6.8 0.5 24.4 1.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 36.6 8.3 0.0 3.6 0.1 0.0 0.0 2.6 0.8 0.1 15.8 0.8 10.4 30.5 60.8 0.1 17.6 0.0 1.1 0.0 0.0 32.6 0.9 0.0 0.0 20.0 9.3 7.3 12.9 0.0 13.8 4.8 4.1 2.4 5.7 4.2 2.2 3.7 0.9 7.2 4.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478334-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.8" "Cell line enhanced" "Detected in some" "AN3-CA: 57.8;BEWO: 19.4;CACO-2: 15.1;HaCaT: 17.4;HAP1: 18.7;NTERA-2: 18.5;T-47d: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 10.8;eosinophil: 4.6" "Lineage enriched" "Detected in single" 35 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" 500000 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favourable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favourable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 2.1 8.8 16.4 3.0 30.3 0.0 9.9 15.8 21.3 6.8 14.1 55.7 5.6 4.2 22.0 6.6 10.2 12.5 12.5 1.4 20.6 11.1 11.4 16.1 13.1 1.0 41.2 13.3 7.4 12.8 25.5 2.5 6.2 30.2 11.7 8.7 16.4 23.8 24.3 0.4 45.4 4.7 18.3 74.8 0.5 9.3 2.9 32.1 0.8 23.4 1.6 3.4 6.9 8.5 0.1 0.1 10.8 0.1 0.1 0.3 0.0 2.2 0.1 9.0 57.8 0.0 0.0 19.4 0.1 0.0 0.0 0.0 15.1 0.3 0.0 4.1 0.9 17.4 18.7 4.0 0.0 0.0 4.0 0.0 0.0 0.3 0.4 0.0 3.8 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 18.5 0.0 0.0 0.0 2.2 5.6 4.9 0.1 0.1 0.1 10.6 0.0 15.5 0.0 0.0 0.1 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 10.8 0.1 4.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 16.4 30.3 15.8 21.3 20.6 11.1 41.2 13.3 30.2 32.1 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease mutation, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 131.7" "Cell line enhanced" "Detected in many" "CACO-2: 19.1;HaCaT: 14.9;Hep G2: 32.1;NTERA-2: 15.6;RT4: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 670000 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: " "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.5 1.5 24.7 1.7 30.3 1.6 4.2 10.2 22.0 4.1 4.9 15.8 3.4 9.9 1.8 2.7 26.9 2.0 5.0 2.0 21.6 11.7 9.6 7.4 4.5 1.3 17.6 21.5 1.1 23.0 1.2 3.0 5.6 15.1 3.7 3.8 1.7 3.8 9.0 1.7 131.7 7.4 1.3 9.0 2.1 4.9 8.1 10.6 0.1 1.3 8.5 7.3 8.5 10.1 0.1 0.6 0.1 0.1 0.2 0.3 0.0 0.0 1.5 9.0 2.6 0.0 0.1 9.2 1.0 0.1 0.4 0.2 19.1 0.4 0.0 7.6 0.3 14.9 2.6 0.1 0.1 0.1 9.6 5.9 1.5 32.1 0.0 0.0 0.1 0.0 5.0 0.1 0.0 0.0 6.4 0.0 0.0 9.5 0.3 0.2 15.6 0.0 0.5 0.5 0.1 1.3 19.1 2.6 0.7 0.8 1.6 0.0 8.9 1.1 0.4 0.0 0.9 0.2 0.6 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.6 0.1 0.0 24.7 30.3 10.2 22.0 21.6 11.7 17.6 21.5 15.1 10.6 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.9;brain: 19.3;lymphoid tissue: 15.0" "Group enriched" "Detected in some" 11 "REH: 27.8;THP-1: 17.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 19.3" "Group enriched" "Detected in some" 11 "myeloid DC: 29.9;plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 16 "dendritic cells: 29.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" 180000 "Endoplasmic reticulum" "HPA047539: " "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.9 0.6 0.6 7.2 1.1 7.5 2.6 19.3 3.5 0.9 1.2 0.1 0.1 0.4 0.8 0.8 1.0 1.2 4.6 0.5 0.9 1.7 2.8 0.7 2.7 15.0 1.8 1.1 0.5 5.7 0.0 0.4 0.0 7.4 0.6 1.4 0.1 2.3 0.6 0.4 1.2 3.0 1.3 4.4 8.8 0.9 1.2 0.0 8.2 0.6 0.0 5.8 2.4 0.7 0.1 29.9 1.4 1.8 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.5 0.0 27.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 1.4 0.0 0.3 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 0.0 0.8 0.0 12.1 0.0 1.2 0.6 1.1 19.3 3.5 0.9 1.7 1.8 1.1 7.4 0.0 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436172 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 235.4;placenta: 433.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 837.5;HSkMC: 391.7;hTERT-HME1: 230.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000126, HPA027066" Enhanced "Secreted to blood" 47000000000 "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavourable (3.44e-8)" "prognostic unfavourable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavourable (3.33e-4)" 20.2 4.5 3.1 13.0 5.2 0.2 13.1 2.2 4.3 21.9 57.1 4.4 235.4 3.5 25.1 27.5 37.4 26.5 20.9 57.3 3.9 2.9 5.8 166.3 81.5 7.9 4.6 5.0 16.9 3.3 1.7 3.5 433.0 6.1 17.1 25.1 5.1 10.4 141.2 9.8 7.0 13.5 114.9 4.6 1.9 21.8 9.0 2.7 9.4 5.4 17.4 2.6 64.7 16.9 0.2 0.8 0.0 0.6 0.0 0.3 0.0 0.2 1.9 2.6 0.5 106.3 837.5 0.1 43.2 28.8 43.7 31.2 26.1 1.0 0.0 0.2 143.6 4.4 0.4 98.4 23.6 0.0 0.1 0.0 0.6 81.5 76.9 0.0 0.1 391.7 0.6 103.4 230.4 50.7 0.1 0.1 87.2 0.3 0.0 0.0 1.2 0.3 0.0 0.0 0.1 1.1 0.3 0.1 0.6 5.1 2.7 28.0 0.4 0.0 97.2 63.4 6.7 69.3 8.0 0.1 0.0 0.0 75.3 0.0 16.4 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 0.0 3.1 5.2 2.2 4.3 3.9 2.9 4.6 5.0 6.1 2.7 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589984-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 47.0;prostate: 44.4" "Cell line enhanced" "Detected in some" "Hep G2: 16.3;MCF7: 35.4;PC-3: 24.7;RT4: 33.1;SK-BR-3: 33.5;T-47d: 47.5" "Cancer enhanced" "Detected in many" "prostate cancer: 127.0" "Region enriched" "Detected in single" 6 "midbrain: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "hypothalamus: 1.0;midbrain: 1.3;thalamus: 1.1" "Region enriched" "Detected in some" 6 "midbrain: 6.1" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: " "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favourable (1.00e-4)" 0.1 0.0 0.1 6.1 0.1 0.0 23.5 0.1 0.3 1.5 9.4 0.1 0.1 4.6 0.1 0.5 7.2 1.3 6.5 0.1 0.1 0.3 0.4 47.0 13.2 0.1 2.0 0.1 0.6 0.2 0.0 1.1 0.1 0.2 44.4 6.0 0.2 9.4 0.7 0.1 0.7 5.1 2.4 0.1 0.1 13.0 0.6 0.1 0.2 0.1 4.4 9.9 12.5 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 7.3 0.9 0.0 0.5 0.0 8.2 4.6 1.1 0.0 0.0 8.1 0.0 1.4 16.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 35.4 0.0 0.1 0.0 24.7 0.0 0.3 0.1 3.4 33.1 4.2 0.0 1.6 33.5 0.0 47.5 0.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.3 2.0 0.1 0.2 0.1 FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22581005-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.4;pancreas: 47.9;stomach 1: 20.7" "Cell line enhanced" "Detected in some" "A549: 10.2;HBEC3-KT: 11.7;Hep G2: 16.2;hTERT-HME1: 7.9;PC-3: 15.1;SCLC-21H: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Region enriched" "Detected in single" 7 "midbrain: 4.9" "CAB001388, HPA066846" Enhanced Supported "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "CAB001388: AB_2262810, HPA066846: " "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "prognostic favourable (7.57e-6)" "unprognostic (6.82e-2)" "unprognostic (1.50e-6)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "prognostic favourable (6.28e-4)" "prognostic favourable (2.34e-4)" "unprognostic (3.18e-1)" "unprognostic (2.55e-15)" "unprognostic (2.50e-2)" "unprognostic (1.68e-1)" "unprognostic (7.12e-2)" "unprognostic (3.93e-3)" 0.2 0.0 0.2 1.3 0.2 0.0 0.2 0.2 0.3 9.7 4.5 0.2 0.2 2.2 1.8 0.2 0.2 3.8 13.1 0.2 0.2 0.1 0.2 44.4 15.9 0.2 1.4 0.2 3.4 47.9 0.0 0.4 0.3 0.4 0.5 6.0 0.2 0.2 0.2 0.2 0.0 1.8 0.2 0.2 0.2 20.7 0.3 0.2 0.2 2.2 0.2 0.9 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.1 0.0 0.0 0.0 11.7 0.0 0.0 0.7 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.3 0.0 7.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.5 0.0 26.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.1 1.4 0.2 0.4 0.2 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075203 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 97.8;skin 1: 61.7" "Cell line enhanced" "Detected in some" "BEWO: 32.6;MCF7: 77.8;RT4: 31.8;SH-SY5Y: 27.3;T-47d: 101.3" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 42 "gdT-cell: 9.7;MAIT T-cell: 13.3;memory CD4 T-cell: 18.2;memory CD8 T-cell: 14.1;naive CD4 T-cell: 10.0;naive CD8 T-cell: 9.0;NK-cell: 16.6;T-reg: 18.9" "Group enriched" "Detected in many" 54 "NK-cells: 16.6;T-cells: 18.9" "Region enriched" "Detected in single" 6 "midbrain: 7.3" "Group enriched" "Detected in some" 46 "midbrain: 25.5;pons and medulla: 17.5;thalamus: 20.0" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavourable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 2.0 2.0 0.3 3.4 0.3 0.9 17.8 0.3 0.3 1.8 0.5 0.1 44.4 0.1 0.4 13.5 0.8 0.4 0.4 0.9 0.3 0.4 12.9 0.7 1.6 2.7 0.8 0.0 0.3 0.4 55.0 3.8 53.4 1.4 8.1 0.0 1.8 8.9 97.8 0.8 61.7 1.2 3.4 0.4 2.7 0.5 0.8 0.1 42.4 3.3 0.6 3.4 26.9 16.4 0.2 0.0 0.3 0.0 16.6 18.9 3.0 5.4 1.3 0.0 0.0 0.0 0.0 32.6 0.1 0.0 0.0 0.0 2.0 4.9 0.0 0.0 0.0 4.7 0.5 0.1 0.0 15.6 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.3 2.5 0.0 0.0 0.0 77.8 8.5 0.0 0.5 0.7 0.4 0.4 0.1 0.0 31.8 1.6 27.3 0.0 4.4 0.0 101.3 0.0 0.0 0.4 1.0 0.2 0.6 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 9.7 0.0 13.3 0.2 18.2 14.1 0.0 0.0 10.0 9.0 0.3 16.6 0.0 0.0 18.9 3.0 0.3 0.3 0.3 0.3 0.3 0.4 0.8 0.0 1.4 0.1 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 80133955-80219402 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "NK-cell: 20.0" "Lineage enriched" "Detected in many" 5 "NK-cells: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome 9000000 Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: " "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavourable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavourable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 33.2 23.4 17.2 5.4 26.2 1.5 14.4 14.4 33.7 9.4 10.5 36.9 3.0 6.9 10.0 3.0 16.6 9.0 8.6 5.7 23.8 18.3 25.9 13.1 10.3 3.4 40.3 21.9 14.3 5.4 2.5 7.3 30.4 26.2 10.1 9.0 2.8 4.9 9.5 4.2 32.4 5.3 12.2 49.7 5.7 8.3 11.1 32.0 0.9 11.1 3.2 4.6 15.5 9.0 0.1 3.7 2.1 1.5 20.0 2.3 0.7 2.9 20.5 18.8 0.1 23.4 15.0 8.6 12.5 15.1 11.1 13.7 0.0 3.2 0.1 4.0 13.4 3.0 10.4 12.8 14.7 0.1 9.6 17.6 18.1 1.2 23.7 2.2 3.8 16.1 32.4 5.9 17.1 7.4 1.4 0.0 20.7 0.5 0.1 0.1 5.4 7.4 8.2 7.2 8.8 33.1 9.9 13.8 9.5 13.4 0.2 10.6 2.5 0.4 13.1 24.8 17.5 5.7 4.7 0.1 0.0 0.1 6.5 1.3 11.0 2.1 0.7 0.7 0.1 0.7 0.0 0.0 0.3 0.2 3.7 0.1 2.3 0.9 0.3 20.0 1.5 0.3 0.2 0.7 17.2 26.2 14.4 25.5 23.8 18.3 40.3 21.9 26.2 32.0 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease mutation, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 303.3;thyroid gland: 304.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favourable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 56.2 79.0 84.2 34.4 44.5 42.1 87.4 86.0 107.4 43.2 42.3 25.4 27.0 33.2 37.2 44.7 41.0 43.6 34.4 106.0 71.0 144.0 39.6 35.3 46.6 44.6 75.8 64.7 43.6 118.1 120.9 303.3 49.8 85.6 36.3 31.5 42.7 171.6 31.1 172.9 26.3 34.9 40.5 61.4 36.9 42.4 18.2 27.4 56.0 304.5 80.6 41.0 37.3 44.6 27.3 41.5 29.9 36.2 25.3 24.2 24.6 9.6 32.5 54.8 25.5 93.1 42.6 49.2 55.8 51.0 63.9 45.8 94.7 50.1 31.7 86.9 72.5 41.8 50.2 74.3 43.3 20.9 30.2 35.2 49.4 62.0 43.1 20.4 22.2 50.7 37.8 31.0 41.7 48.3 30.9 43.3 42.0 132.2 104.3 50.1 17.4 34.4 64.2 48.0 55.9 51.2 38.2 68.0 155.7 77.6 77.0 62.2 58.9 56.1 53.1 84.8 76.2 30.5 52.5 75.9 49.0 66.9 37.2 10.0 43.2 29.9 24.8 29.5 20.7 35.7 22.1 26.7 22.0 22.2 37.8 27.3 21.3 24.2 29.1 25.3 36.2 41.5 23.3 24.6 84.2 44.5 86.0 107.4 71.0 144.0 75.8 64.7 85.6 27.4 GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794231-92839963 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" 20.8 20.3 16.8 15.7 17.3 6.5 24.4 11.6 17.5 24.9 20.4 17.2 25.5 16.5 18.2 41.7 21.2 15.3 17.5 18.3 17.5 15.6 21.5 51.0 16.6 18.2 18.6 14.6 18.9 26.8 23.6 27.2 44.4 16.4 23.4 23.7 12.7 24.3 30.2 20.6 18.9 25.6 18.9 19.4 16.9 23.0 23.5 17.6 13.5 24.8 17.8 16.4 20.7 15.8 9.7 9.7 22.2 12.7 8.1 12.4 6.3 12.6 11.6 10.5 9.6 22.1 30.0 18.1 17.5 32.3 17.1 20.2 8.5 17.4 8.2 14.4 27.8 13.3 9.3 14.3 23.3 10.0 4.4 7.7 5.8 11.4 25.7 9.0 13.0 23.0 26.0 12.0 24.9 16.8 6.8 11.1 18.7 23.4 6.9 7.8 6.5 12.5 5.4 15.5 8.2 17.4 15.4 7.5 10.6 15.9 12.0 17.8 20.6 10.0 13.9 9.8 6.5 12.7 8.7 13.6 10.5 7.2 22.6 7.2 16.4 9.1 9.8 22.2 10.9 12.7 12.3 9.7 11.1 11.1 9.7 9.2 9.9 8.6 8.7 8.1 10.8 9.1 12.4 6.3 16.8 17.3 11.6 17.5 17.5 15.6 18.6 14.6 16.4 17.6 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734357 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 167.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018139 Enhanced "Intracellular and membrane" 7000000 "HPA018139: AB_1849903" "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavourable (1.61e-4)" "prognostic favourable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favourable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 6.1 21.0 12.7 8.0 19.1 5.5 10.7 19.4 35.7 10.6 15.9 16.0 33.3 10.6 10.4 19.5 17.7 13.5 8.9 78.1 15.8 16.7 24.6 85.5 7.1 11.1 16.2 17.8 8.7 8.8 27.0 13.0 7.3 27.7 17.2 18.8 23.4 13.0 20.5 167.8 10.4 9.4 13.5 12.3 8.0 13.6 10.8 9.9 10.7 12.3 53.9 15.0 15.5 11.2 14.3 17.6 3.5 9.9 14.5 24.5 14.3 27.1 36.9 19.5 23.6 14.1 12.8 25.5 20.9 22.3 41.2 22.6 31.9 24.6 60.8 24.9 23.1 40.2 41.6 40.6 52.6 16.7 38.2 16.4 20.1 35.6 17.9 26.2 15.1 12.3 23.1 25.9 22.7 41.3 32.8 6.3 20.9 24.3 32.6 25.4 26.4 71.7 35.8 29.7 58.3 38.9 40.0 31.1 22.6 40.0 43.1 15.0 21.8 8.6 16.6 15.0 27.5 11.7 26.5 14.6 13.5 49.8 16.1 26.3 15.1 2.3 9.9 3.5 15.2 8.6 23.5 14.3 18.0 18.4 17.6 10.6 16.7 15.3 0.9 14.5 8.5 15.5 24.5 14.3 12.7 19.1 19.4 35.7 15.8 16.7 16.2 17.8 27.7 9.9 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Uncertain "Cytoplasmic bodies" "Cytoplasmic bodies" "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favourable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavourable (4.61e-5)" 13.0 12.4 26.1 10.9 31.1 5.2 17.1 40.9 31.2 11.0 18.2 9.3 15.6 11.1 12.3 20.8 8.6 7.5 8.2 11.9 26.4 22.9 34.5 49.0 14.1 7.3 18.3 11.5 7.2 22.9 17.4 24.5 5.8 13.9 11.1 13.2 7.4 10.8 21.3 23.4 10.7 10.8 11.6 16.4 5.6 13.5 7.8 16.2 3.1 12.2 10.0 6.8 7.4 15.1 3.1 3.0 0.5 2.5 2.3 6.2 1.5 22.3 4.4 7.8 8.6 9.3 7.9 5.0 6.4 3.1 6.5 6.6 1.3 10.1 0.0 1.1 3.1 7.9 7.8 12.4 8.6 6.8 8.5 6.6 6.3 13.6 4.8 3.7 9.9 6.7 7.3 1.8 7.2 7.6 4.5 8.5 3.6 11.9 6.6 14.0 3.3 10.2 0.0 15.1 6.5 10.5 4.4 13.9 5.4 4.3 19.0 7.0 10.2 6.4 2.8 6.6 14.6 6.4 6.5 11.3 4.8 0.1 5.2 0.5 6.3 0.0 1.3 0.5 3.9 2.5 6.2 2.4 4.9 2.9 1.9 3.1 3.5 3.3 0.0 2.3 1.9 3.0 5.3 1.5 26.1 31.1 40.9 27.0 26.4 22.9 18.3 11.5 13.9 16.2 GPS2 ENSG00000132522 "G protein pathway suppressor 2" Q13227 17 7311324-7315564 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067540 Approved Supported Nucleoplasm Nucleoplasm "HPA067540: " "unprognostic (1.53e-2)" "unprognostic (3.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.71e-3)" "unprognostic (1.55e-1)" "unprognostic (1.53e-4)" "unprognostic (1.37e-2)" "unprognostic (1.33e-1)" "unprognostic (3.18e-2)" "unprognostic (2.84e-1)" "prognostic favourable (7.50e-5)" "unprognostic (1.37e-2)" "prognostic unfavourable (3.42e-5)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (6.87e-2)" "unprognostic (1.28e-3)" 21.8 22.8 21.1 17.6 20.9 27.8 25.0 18.2 25.4 18.5 23.4 19.1 14.4 14.4 20.0 15.5 24.6 19.9 15.5 35.3 19.9 17.1 28.7 30.1 18.5 15.2 19.5 16.9 20.9 23.0 26.6 21.1 21.9 16.5 17.5 20.2 14.3 19.7 21.5 72.4 23.0 25.7 18.2 21.2 20.6 18.0 45.8 22.1 21.2 22.4 21.0 21.1 19.2 25.0 55.2 48.3 58.1 46.4 28.2 57.0 38.8 19.4 37.8 12.1 16.5 24.1 13.6 13.9 14.1 16.7 28.6 24.7 26.2 10.0 22.0 10.7 19.4 26.7 15.3 27.5 22.2 26.8 24.1 20.4 35.9 32.4 17.1 12.2 23.7 12.8 19.1 39.3 10.5 16.7 12.3 5.2 29.6 16.4 23.7 12.9 16.5 15.8 18.2 22.4 22.5 21.2 22.0 16.1 27.0 23.0 14.8 19.3 14.5 11.9 10.0 13.4 13.8 18.5 32.8 17.2 24.4 14.7 20.1 14.4 23.4 44.1 35.3 58.1 40.8 43.0 38.4 55.2 45.5 45.8 29.5 43.3 42.5 38.5 56.4 28.2 46.4 48.3 57.0 38.8 21.1 20.9 18.2 25.4 19.9 17.1 19.5 16.9 16.5 22.1 GTF2H1 "BTF2, P62, TFIIH" ENSG00000110768 "General transcription factor IIH subunit 1" P32780 11 18322295-18367044 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004637, HPA046660" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB004637: AB_425470, HPA046660: " "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "unprognostic (9.78e-2)" "unprognostic (2.38e-1)" "unprognostic (2.63e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (5.98e-9)" "unprognostic (7.71e-2)" "unprognostic (4.24e-2)" "unprognostic (2.81e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (7.42e-3)" "unprognostic (8.31e-2)" "unprognostic (1.24e-1)" "unprognostic (7.90e-2)" "unprognostic (2.94e-1)" 27.1 26.4 24.1 18.2 28.8 10.5 33.0 32.6 35.7 21.5 21.6 19.3 24.1 18.0 23.5 23.1 26.2 18.6 22.9 21.4 24.1 20.4 25.9 25.0 19.1 23.7 19.6 22.2 27.2 24.3 27.1 32.4 24.3 27.4 22.5 20.9 21.2 25.8 26.0 20.8 32.4 21.7 20.6 21.1 23.4 20.5 38.5 23.3 22.7 29.3 21.7 25.7 22.9 22.2 12.0 11.8 20.3 12.1 15.9 13.9 8.8 12.2 11.4 9.5 13.6 21.9 17.5 12.0 18.4 19.8 16.3 18.9 11.8 4.8 20.5 7.4 18.9 17.1 15.6 16.8 21.2 9.0 15.5 13.3 11.6 11.9 31.3 25.5 14.5 19.7 20.2 10.1 32.1 14.4 20.4 10.9 23.5 11.4 12.8 20.3 8.4 16.4 13.2 20.3 9.5 13.4 16.9 11.0 11.8 15.2 14.7 22.7 7.7 15.0 10.6 22.1 10.7 39.5 14.9 5.6 13.2 15.1 19.1 20.0 21.0 20.3 10.9 11.3 9.1 11.0 9.8 11.7 11.5 10.1 11.8 12.0 13.9 11.1 7.9 15.9 12.1 6.5 11.0 8.8 24.1 28.8 32.6 35.7 24.1 20.4 19.6 22.2 27.4 23.3 H3F3C H3.5 ENSG00000188375 "H3 histone family member 3C" Q6NXT2 12 31791185-31792241 "Cancer-related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "blood: 34.7;testis: 23.5" "Cell line enhanced" "Detected in many" "SH-SY5Y: 5.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in all" "neutrophil: 34.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 34.7" HPA042570 Approved "HPA042570: " "unprognostic (2.82e-1)" "unprognostic (2.80e-4)" "unprognostic (2.60e-2)" "unprognostic (9.21e-2)" "unprognostic (3.77e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "unprognostic (1.45e-1)" "unprognostic (7.56e-2)" "unprognostic (2.39e-1)" "unprognostic (4.06e-2)" "unprognostic (3.53e-2)" "unprognostic (2.73e-3)" "unprognostic (4.02e-2)" "unprognostic (2.99e-2)" "unprognostic (2.80e-2)" "unprognostic (3.86e-2)" 1.8 0.5 0.5 2.1 0.9 4.2 1.6 0.6 0.6 2.0 0.8 0.6 1.3 0.9 1.8 1.7 1.9 0.8 0.8 0.5 1.1 0.5 0.5 1.1 1.0 0.7 0.6 0.9 3.1 1.0 0.5 0.6 0.7 0.6 1.5 0.3 1.5 1.7 1.4 0.6 1.3 1.2 1.7 0.6 1.9 1.0 23.5 0.9 0.9 1.0 3.3 1.1 1.7 0.8 6.7 6.1 34.7 7.0 6.7 6.1 14.9 3.6 0.7 1.6 0.7 0.4 0.0 1.4 0.5 0.2 0.9 0.4 1.1 1.5 0.5 1.4 0.0 1.2 0.1 0.1 0.2 1.1 0.0 0.1 0.9 0.5 0.0 1.0 1.3 0.2 0.1 0.0 1.2 0.1 0.4 1.6 0.0 0.1 2.7 3.6 0.7 0.2 1.7 0.8 2.4 0.2 0.6 2.9 5.5 0.1 2.1 4.0 1.2 3.5 0.3 2.0 3.5 1.4 4.5 2.7 1.0 1.4 1.7 1.7 1.7 13.8 6.7 18.9 5.1 7.0 4.5 6.7 5.3 5.0 6.1 5.2 5.6 5.3 34.7 6.7 6.1 5.9 6.1 14.9 0.5 0.9 0.6 0.5 1.1 0.5 0.6 0.9 0.6 0.9 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699008-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 116.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 44.8;HHSteC: 35.1;HL-60: 19.6;hTEC/SVTERT24-B: 22.0;Karpas-707: 60.7;U-87 MG: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "basophil: 33.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 33.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved Approved Centrosome,Cytosol "Secreted to blood" Cytosol Centrosome "CAB010333: AB_647965, HPA040360: , HPA044088: " "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavourable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 6.2 10.6 1.4 2.9 1.2 4.6 4.8 0.5 4.5 5.1 4.0 0.4 2.9 1.5 5.2 3.1 2.9 4.0 7.1 9.3 3.6 1.3 7.3 27.5 15.8 2.0 1.3 1.4 3.2 1.4 1.6 4.3 116.9 1.9 10.8 1.9 2.0 2.2 3.2 1.4 0.9 1.8 15.1 6.0 6.6 2.3 2.0 0.9 0.5 5.3 1.4 1.4 10.5 21.5 0.0 2.0 33.5 7.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 5.5 44.8 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 35.1 19.6 0.1 10.6 0.0 22.0 0.0 0.5 0.0 60.7 0.1 0.0 0.0 13.6 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 16.1 4.1 0.0 33.5 6.6 1.6 0.0 7.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.3 0.0 6.7 0.4 0.0 1.5 1.4 1.2 0.5 4.5 3.6 1.3 1.3 1.4 1.9 0.9 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" "P16188, P04439, P13746" 6 29941260-29945884 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 154.8;fHDF/TERT166: 41.4;HBEC3-KT: 42.5;RPMI-8226: 40.3;U-266/70: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" CAB078470 Supported "Golgi apparatus,Plasma membrane" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favourable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favourable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 69.4 57.5 16.0 69.1 18.2 41.2 40.8 9.1 20.7 54.4 92.6 20.4 28.6 105.7 38.4 76.2 48.4 27.8 92.3 59.1 14.6 16.6 80.5 47.6 112.0 90.5 19.5 8.9 57.2 30.0 22.5 33.3 38.7 22.7 64.1 38.5 52.4 28.3 19.2 44.0 110.4 129.4 30.3 22.8 150.0 115.9 26.6 12.3 71.1 62.3 38.5 97.7 86.4 41.0 23.0 10.9 65.8 25.2 25.9 46.7 45.4 154.8 3.9 0.0 0.0 25.0 23.6 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.4 0.0 41.4 3.8 0.0 42.5 0.0 0.3 1.5 27.0 1.2 0.8 1.4 0.0 1.8 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 2.4 0.3 0.4 3.3 0.3 40.3 29.0 31.8 0.0 1.4 3.5 0.0 1.4 0.1 3.6 0.5 2.3 0.1 0.7 0.4 41.3 10.5 8.7 0.0 22.8 0.0 65.8 25.2 35.4 38.3 17.9 28.8 23.0 29.6 34.4 4.1 14.9 21.7 29.7 47.9 25.9 19.8 10.9 46.7 45.4 16.0 18.2 9.1 20.7 14.6 16.6 19.5 8.9 22.7 12.3 HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" "P30486, Q29836, Q31610, Q31612, P01889, P30480" 6 31269491-31357188 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 69.9;EFO-21: 63.8;U-266/70: 161.8;U-698: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" CAB015418 Enhanced "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favourable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" 83.5 40.1 11.7 91.4 14.2 11.0 52.6 6.7 13.1 41.4 96.5 18.2 15.6 2.0 52.8 51.5 46.1 30.8 100.3 76.8 11.9 13.4 63.3 57.1 194.5 214.9 17.3 10.5 40.2 21.8 16.2 20.2 39.5 19.1 70.4 56.1 45.4 108.9 23.4 37.4 56.4 164.1 20.6 23.8 200.6 43.2 32.1 11.9 54.1 44.5 19.1 136.3 117.6 48.6 45.6 41.4 118.7 56.5 46.5 64.3 81.8 69.9 0.0 0.0 0.0 1.7 12.0 0.4 0.0 0.3 0.1 0.2 0.0 0.5 2.5 63.8 12.4 29.4 14.5 12.8 0.0 0.2 3.4 0.9 0.0 0.0 9.4 0.0 0.6 23.6 0.0 0.0 1.6 0.0 0.1 3.4 0.0 0.0 0.3 18.2 0.2 0.0 2.1 0.4 0.4 19.3 0.0 0.1 0.5 0.6 0.1 0.1 11.1 0.7 15.0 3.8 0.6 0.6 0.2 161.8 36.0 44.3 0.2 0.7 0.1 20.6 56.5 59.1 64.3 42.7 62.2 45.6 54.9 58.5 41.4 35.1 42.1 55.2 118.7 46.5 37.4 33.9 56.2 81.8 11.7 14.2 6.7 13.1 11.9 13.4 17.3 10.5 19.1 11.9 HMGXB4 "HMG2L1, THC211630" ENSG00000100281 "HMG-box containing 4" Q9UGU5 22 35257452-35295807 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000725 Approved "HPA000725: AB_1079073" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "prognostic favourable (3.24e-5)" "unprognostic (4.81e-2)" "unprognostic (1.93e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (4.79e-4)" "unprognostic (2.85e-2)" "unprognostic (8.25e-3)" "unprognostic (6.67e-3)" "prognostic unfavourable (1.16e-4)" "unprognostic (1.62e-1)" "unprognostic (8.71e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" 13.6 11.6 11.4 11.4 17.6 28.6 13.6 17.4 15.1 14.4 10.9 17.2 9.5 10.6 17.4 8.4 14.4 14.5 10.8 9.8 10.0 8.6 8.6 8.0 10.2 10.5 14.4 13.8 21.7 10.9 9.4 7.6 20.2 12.4 12.4 12.2 8.7 11.9 12.7 17.2 14.4 13.1 15.0 12.6 10.0 10.3 12.1 16.9 20.0 10.6 10.2 11.6 14.8 13.5 11.8 9.4 22.6 12.5 7.4 13.1 4.7 12.9 2.9 20.2 10.1 4.9 9.7 5.8 13.4 17.7 13.1 12.2 2.2 4.8 15.5 6.0 13.3 8.0 8.7 9.4 15.3 13.6 9.8 14.2 3.8 2.8 6.7 29.8 14.5 8.8 8.2 11.0 8.4 9.0 11.1 12.9 9.7 5.9 18.0 7.2 9.4 8.7 14.5 19.1 5.4 7.4 9.5 12.8 12.6 12.0 8.7 9.6 6.0 9.3 8.3 12.0 26.5 13.9 11.0 13.8 13.5 19.3 10.1 9.1 17.0 22.6 11.1 13.8 12.6 12.5 10.8 8.9 12.1 13.1 8.8 11.8 8.1 9.2 16.8 7.4 11.5 9.4 10.1 4.7 11.4 17.6 17.4 15.1 10.0 8.6 14.4 13.8 12.4 16.9 HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537287 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB002015: , HPA049830: , HPA070222: " "unprognostic (3.06e-2)" "unprognostic (2.98e-2)" "unprognostic (7.01e-2)" "unprognostic (3.08e-3)" "unprognostic (3.49e-3)" "unprognostic (3.87e-1)" "prognostic unfavourable (2.32e-4)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (9.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" 12.3 11.4 25.2 9.1 34.5 5.0 16.2 16.1 25.3 7.9 9.5 8.1 10.8 8.9 6.2 9.2 22.3 8.3 10.9 28.7 22.2 22.4 8.2 6.5 8.9 8.0 23.2 12.9 7.7 9.7 11.7 10.3 10.1 15.0 10.0 6.2 8.2 10.1 12.7 51.8 32.0 8.2 8.4 17.0 6.5 7.2 6.1 11.0 5.9 8.1 24.5 9.3 9.9 19.8 2.1 1.1 0.7 4.6 0.1 2.0 0.3 21.8 19.4 9.3 8.3 5.8 4.1 12.0 10.9 5.8 17.1 14.6 9.8 8.7 8.4 3.4 14.8 17.4 9.9 26.5 4.8 6.9 22.1 4.3 7.8 8.5 8.8 3.4 3.3 6.2 29.6 9.2 10.0 8.5 8.8 12.3 9.6 17.9 12.7 12.1 9.4 19.3 10.2 11.8 7.5 9.6 5.4 36.3 14.4 10.1 18.1 7.8 14.8 6.7 13.5 15.3 12.1 5.6 14.0 4.6 6.1 6.5 14.4 6.3 14.3 0.0 0.6 0.7 1.4 1.2 1.6 0.8 1.4 1.3 0.7 2.1 2.0 0.6 0.0 0.1 4.6 1.1 2.0 0.3 25.2 34.5 16.1 21.1 22.2 22.4 23.2 12.9 15.0 11.0 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" 62000000 Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favourable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavourable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 79.9 116.1 88.0 65.9 105.0 74.6 107.8 92.1 118.2 92.3 60.4 61.7 80.9 40.6 113.3 107.6 71.6 138.4 63.8 115.0 89.0 110.5 72.0 70.7 76.2 73.8 109.7 94.4 238.4 113.9 151.6 95.3 83.6 133.7 93.5 76.4 52.7 64.8 100.3 197.1 67.9 49.0 102.1 93.9 57.5 77.3 45.9 100.2 58.3 133.8 89.8 102.5 86.2 223.4 75.9 50.5 7.2 45.7 55.7 82.5 74.9 138.6 89.0 79.1 97.1 54.3 56.9 82.8 62.7 61.5 116.1 81.8 133.0 42.5 177.7 68.0 65.2 80.9 192.3 93.3 143.7 58.8 77.8 138.3 50.4 173.8 39.3 138.0 95.8 52.5 63.2 91.2 78.8 111.1 184.5 66.3 78.9 140.0 114.9 83.3 92.2 68.2 110.9 80.8 97.5 78.5 84.4 115.8 70.8 48.7 70.6 87.9 91.8 69.1 69.6 69.3 116.0 56.6 143.1 76.8 120.4 321.0 75.3 101.5 78.9 7.2 30.2 6.8 49.3 45.7 82.5 75.9 55.2 56.4 50.5 63.2 75.2 71.3 3.7 55.7 43.3 31.4 42.6 74.9 88.0 105.0 92.1 118.2 89.0 110.5 109.7 94.4 133.7 100.2 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles 210000000 Nucleoplasm Vesicles "CAB002056: , HPA052504: " "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favourable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavourable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favourable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 70.0 96.8 93.7 78.1 102.8 58.1 73.8 119.5 125.1 52.8 64.1 72.0 77.3 77.7 59.9 98.3 83.4 76.2 76.7 106.4 83.1 102.4 128.6 114.2 68.9 93.3 105.7 72.4 66.7 191.1 97.2 98.3 71.6 169.2 65.3 81.0 53.1 62.4 69.9 224.6 31.2 74.4 75.4 91.8 79.7 92.7 58.3 98.1 92.9 90.9 98.3 124.4 76.1 123.2 77.4 47.5 41.1 84.2 76.1 124.3 200.0 82.8 125.6 83.4 72.0 77.2 82.8 110.5 164.7 91.3 201.5 121.3 188.4 109.0 134.9 104.0 91.6 112.9 238.2 59.7 201.2 116.6 36.2 146.4 59.0 91.8 21.1 142.2 112.5 44.1 96.6 61.9 19.3 107.8 158.4 70.2 161.4 73.8 147.8 105.6 131.9 111.9 133.4 59.5 76.3 104.4 60.6 85.6 64.9 120.0 130.3 45.4 113.6 55.7 105.9 101.2 81.3 87.0 145.9 47.4 116.9 115.8 112.8 203.3 122.1 30.3 41.5 41.1 96.5 82.9 115.9 77.4 113.4 105.2 47.5 53.7 109.6 105.1 14.9 76.1 84.2 34.4 124.3 200.0 93.7 102.8 119.5 125.1 83.1 102.4 105.7 72.4 169.2 98.1 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase" Q7Z6Z7 X 53532096-53686729 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol 3400 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 24.6 28.2 27.7 23.8 43.3 22.4 28.0 37.0 41.1 31.8 25.9 34.3 26.6 17.1 31.9 52.4 27.4 26.5 23.1 27.1 28.0 31.8 30.3 26.2 20.3 23.1 30.0 30.2 43.3 27.8 59.8 34.2 27.2 34.6 27.3 22.7 25.6 26.4 29.6 59.1 50.1 22.1 33.9 23.9 26.6 25.7 28.4 27.7 32.4 27.6 20.7 28.6 27.0 22.9 5.1 7.2 8.2 7.0 6.9 8.9 3.5 50.1 30.9 20.1 14.2 35.3 21.1 24.8 15.1 19.5 15.9 16.7 23.5 16.2 26.3 10.3 27.4 24.1 45.4 25.3 21.8 37.9 20.1 20.9 27.7 18.3 32.5 31.3 12.9 20.1 19.0 38.2 43.9 27.5 20.8 17.1 20.6 30.9 16.9 17.5 27.5 22.3 15.7 27.8 15.9 26.4 34.8 16.8 12.1 42.6 19.0 13.6 27.2 15.2 35.0 14.7 21.1 20.9 19.2 15.0 14.7 23.0 15.7 30.7 21.1 4.0 4.7 8.2 7.2 3.8 8.9 5.1 6.9 7.6 6.7 5.1 4.9 4.9 4.2 6.9 7.0 7.2 5.7 3.5 27.7 43.3 37.0 41.1 28.0 31.8 30.0 30.2 34.6 27.7 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1, cytosolic" O75874 2 208236227-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 108.5;RT4: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" 16000000 "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: , HPA035248: AB_10600714, HPA057936: " "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavourable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavourable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 41.3 82.3 6.2 8.8 7.0 1.3 20.9 6.5 8.3 12.6 35.2 8.7 38.0 30.6 8.0 29.9 30.3 8.8 18.7 10.8 6.3 6.2 20.5 91.0 19.8 14.3 8.1 4.7 19.4 21.5 4.8 6.2 24.1 8.7 38.5 23.1 15.4 18.7 39.0 4.7 7.4 54.1 10.1 9.3 21.3 20.4 15.6 8.4 3.5 7.9 11.0 11.9 43.4 12.1 4.9 22.8 6.4 31.6 7.4 6.6 12.0 9.6 16.2 23.2 9.4 42.2 30.1 13.2 4.0 18.4 6.8 16.6 25.6 23.6 1.9 25.6 12.5 14.9 16.7 19.4 6.6 1.3 6.3 8.3 13.4 108.5 56.2 5.4 8.3 25.9 41.3 15.5 11.3 18.7 8.3 6.7 10.4 6.1 3.8 9.3 42.4 6.7 3.7 8.4 5.4 30.6 75.8 4.0 6.9 15.3 14.8 50.1 5.7 15.8 12.3 6.9 7.0 9.8 4.3 3.2 5.0 2.5 22.4 32.8 5.5 5.7 31.6 4.8 4.5 14.5 5.1 4.9 4.0 5.3 22.8 4.9 3.3 3.9 6.4 7.4 6.5 8.4 6.6 12.0 6.2 7.0 6.5 8.3 6.3 6.2 8.1 4.7 8.7 8.4 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2, mitochondrial" P48735 15 90083045-90102504 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 126.2;skeletal muscle: 190.7" "Cell line enhanced" "Detected in all" "MOLT-4: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria 53000000 Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favourable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 5.4 2.0 14.9 10.1 16.6 22.6 8.8 4.9 19.1 6.4 16.2 13.8 12.4 16.1 5.9 15.3 23.7 6.0 9.4 126.2 10.2 9.3 25.0 93.2 6.9 15.8 14.4 12.0 3.0 25.1 8.4 3.3 15.1 11.9 13.3 14.5 6.0 28.0 21.9 190.7 11.0 13.9 15.8 11.0 7.5 27.9 1.2 7.6 28.2 3.4 69.0 13.6 11.0 8.6 16.8 32.8 17.2 56.3 22.2 29.5 31.2 10.2 5.8 30.2 30.0 4.2 5.2 25.7 12.8 19.5 12.1 13.0 2.7 8.9 12.2 3.6 10.6 3.5 4.4 3.9 5.8 23.9 2.9 20.8 2.2 20.3 5.1 14.2 21.1 10.8 2.2 2.9 2.3 24.8 3.1 10.5 9.3 29.8 68.3 22.1 9.0 2.4 57.9 21.7 36.3 18.7 12.3 43.6 22.1 15.9 63.6 5.1 51.3 43.9 5.9 21.7 3.1 2.8 5.9 17.3 3.2 1.4 6.9 30.0 12.5 9.0 26.4 17.2 26.1 48.0 12.4 16.8 18.7 29.5 32.8 9.8 10.2 18.2 5.1 22.2 56.3 17.8 15.9 31.2 14.9 16.6 4.9 19.1 10.2 9.3 14.4 12.0 11.9 7.6 IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752698-109786568 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 70.1" "Cell line enhanced" "Detected in many" "hTERT-HME1: 18.0;SH-SY5Y: 18.9;THP-1: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol Cytosol Aggresome "CAB016944: , HPA054664: " "unprognostic (2.87e-3)" "unprognostic (5.73e-3)" "unprognostic (4.39e-2)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (5.49e-3)" "unprognostic (2.10e-1)" "unprognostic (9.28e-2)" "unprognostic (9.70e-2)" "unprognostic (2.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.09e-2)" "unprognostic (6.21e-3)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (3.17e-2)" "unprognostic (1.24e-1)" 38.9 24.3 27.6 10.9 25.2 70.1 33.5 19.6 30.6 13.5 10.9 13.0 6.7 8.7 14.4 12.2 7.1 7.7 8.4 13.5 23.6 14.6 7.7 24.6 11.6 5.3 24.2 22.1 27.1 7.9 6.1 23.0 13.6 19.5 20.0 7.5 9.3 11.5 12.2 20.9 15.3 9.7 9.7 25.1 9.0 8.3 6.3 21.3 2.0 10.7 4.7 5.3 8.4 17.8 0.5 0.1 6.9 1.4 0.2 0.5 0.2 2.6 3.0 1.9 0.0 16.5 3.3 1.0 2.9 3.4 1.7 1.5 0.2 3.2 0.0 1.8 2.0 1.2 1.0 2.6 2.2 1.0 13.6 1.2 4.3 0.0 16.7 4.7 1.5 6.9 13.9 0.5 18.0 0.6 0.8 0.0 17.0 1.3 0.0 13.9 2.1 0.6 5.9 1.8 1.2 4.9 0.7 2.9 18.9 1.5 0.0 11.6 0.3 28.3 0.0 3.7 0.0 0.2 3.8 0.0 1.3 0.9 2.7 4.6 6.3 2.7 1.4 1.9 0.2 0.3 0.3 0.1 0.4 0.1 0.1 0.5 0.5 0.4 6.9 0.2 0.4 0.1 0.5 0.2 27.6 25.2 19.6 30.6 23.6 14.6 24.2 22.1 19.5 21.3 ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506282 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 50.1;HaCaT: 55.2;HBEC3-KT: 108.5;hTCEpi: 47.3;hTERT-HME1: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 16.2" "Group enriched" "Detected in many" 34 "granulocytes: 16.2;NK-cells: 5.5;T-cells: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced 45000000 "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favourable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" 28.0 3.1 9.8 19.1 10.5 1.6 30.1 3.0 8.4 27.0 34.9 9.4 42.3 28.5 28.2 11.3 17.0 11.1 23.8 21.7 9.7 8.2 22.0 4.9 29.0 14.9 9.8 5.1 7.6 31.3 7.4 4.9 38.7 12.6 14.3 25.2 17.6 37.1 32.4 13.5 17.5 44.2 15.2 9.6 14.9 25.0 12.4 6.9 15.1 11.5 35.2 13.2 24.1 17.3 0.3 0.1 16.2 0.2 5.5 10.0 3.3 11.4 9.8 4.3 7.7 0.2 0.1 23.6 50.1 5.4 5.1 3.2 5.5 22.0 0.1 14.1 13.3 55.2 2.8 108.5 9.3 0.1 2.6 0.2 10.5 9.1 0.7 3.1 0.3 1.0 47.3 0.3 48.1 32.8 0.0 0.8 6.4 0.5 0.8 2.7 7.8 8.4 0.1 12.8 0.2 7.8 16.1 0.1 0.5 9.2 0.0 10.7 2.0 0.2 14.7 7.2 6.5 13.2 8.6 0.7 0.5 0.3 0.2 1.1 28.9 2.6 0.2 16.2 4.2 0.0 8.5 0.2 5.4 5.0 0.1 0.3 10.0 4.6 0.5 5.5 0.0 0.0 5.7 3.3 9.8 10.5 3.0 8.4 9.7 8.2 9.8 5.1 12.6 6.9 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "ASC diff: 18.9;HDLM-2: 26.7;HEL: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: , HPA043870: " "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.4 1.4 2.5 18.9 4.9 0.4 3.4 2.9 2.6 1.7 0.1 0.8 0.1 0.8 2.0 0.8 1.5 2.1 1.9 26.7 0.5 54.8 2.9 0.7 3.9 3.7 2.8 4.0 0.9 1.1 1.8 2.4 3.9 6.4 4.7 0.9 0.9 5.2 1.3 1.7 1.9 2.7 0.7 2.0 1.3 1.6 0.9 1.0 1.5 1.0 0.7 6.5 5.0 4.0 1.3 4.1 2.4 1.2 2.2 0.5 5.2 1.8 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell line enhanced" "Detected in many" "CACO-2: 32.1;HEL: 19.6;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.6 1.4 0.8 1.4 0.6 32.1 2.5 0.1 0.4 3.6 0.2 0.8 0.0 1.1 0.0 0.3 19.6 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.6 4.5 0.1 0.4 2.3 0.0 0.0 2.0 3.1 1.0 1.6 0.0 0.1 0.3 1.2 9.2 0.4 0.3 0.3 0.7 0.1 8.1 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 KDM5C "DXS1272E, JARID1C, MRX13, SMCX, XE169" ENSG00000126012 "Lysine demethylase 5C" P41229 X 53191321-53225422 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038244, HPA046147" Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA038244: , HPA046147: " "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.56e-2)" "unprognostic (7.10e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (2.08e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.45e-2)" "unprognostic (1.58e-2)" "unprognostic (5.05e-3)" "unprognostic (1.96e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" 19.5 22.9 22.4 22.6 24.7 26.3 17.9 43.0 31.7 25.9 19.5 23.4 16.7 22.2 29.2 13.3 26.9 24.8 15.2 17.6 21.6 15.3 17.0 18.8 20.6 25.8 24.6 21.8 33.1 22.5 37.7 31.8 34.0 22.8 18.7 13.5 17.0 25.6 17.1 36.6 28.4 22.2 23.6 16.0 25.0 19.4 10.6 26.2 29.0 22.2 11.3 24.5 21.5 26.4 4.5 4.3 4.8 4.0 2.8 6.1 3.8 17.3 23.8 25.5 19.5 17.7 16.2 18.1 10.9 12.8 14.8 13.8 16.0 11.4 16.2 14.2 14.3 15.6 28.8 23.3 11.3 12.1 42.6 15.7 25.3 11.3 21.8 18.6 31.4 12.7 17.2 28.9 35.6 21.8 30.6 10.8 10.8 22.3 13.6 20.9 21.6 22.3 15.4 15.2 17.6 9.4 16.7 19.2 24.8 33.1 30.7 12.4 21.5 16.4 14.9 16.5 14.3 14.8 10.5 15.7 12.8 12.4 21.4 22.1 12.2 3.0 3.8 2.7 6.1 3.6 5.1 4.5 3.7 5.7 3.1 3.2 4.5 2.9 4.8 2.8 4.0 4.3 4.3 3.8 22.4 24.7 43.0 31.7 21.6 15.3 24.6 21.8 22.8 26.2 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873177-45112602 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved Nucleoplasm,Nucleoli "Intracellular and membrane" Nucleoplasm Nucleoli "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 12.3 12.1 16.5 17.6 24.5 47.9 21.4 26.1 22.0 16.9 11.8 16.7 12.0 13.1 22.6 11.3 15.4 16.9 15.2 9.1 18.2 6.5 11.6 13.5 19.7 15.1 28.8 11.3 23.8 14.9 21.3 20.2 13.3 18.3 10.3 11.3 10.3 16.1 12.6 15.1 21.3 17.6 13.5 14.9 18.1 15.0 17.7 26.1 19.1 14.5 6.9 13.6 14.9 22.8 5.5 7.1 15.7 7.5 6.2 7.9 3.5 8.9 7.8 11.6 11.7 8.3 8.6 24.9 7.0 5.0 8.4 8.8 18.4 7.7 5.9 3.8 6.5 19.3 14.8 12.3 7.8 8.5 15.9 7.3 9.9 6.8 5.9 3.9 20.7 4.6 10.2 13.8 14.5 6.5 10.1 14.6 5.2 5.8 8.1 11.5 9.7 9.0 9.0 11.1 1.0 4.8 16.8 10.0 5.4 22.3 11.2 9.5 10.8 0.1 5.5 8.0 6.2 8.0 3.6 9.2 11.1 8.9 5.6 4.1 4.6 15.7 3.8 3.5 5.3 7.5 6.0 5.5 7.2 7.9 7.1 3.8 7.0 6.3 7.3 6.2 7.2 3.8 5.6 3.5 16.5 24.5 26.1 22.0 18.2 6.5 28.8 11.3 18.3 26.1 KEAP1 "INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454" ENSG00000079999 "Kelch like ECH associated protein 1" Q14145 19 10486120-10503741 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005558, CAB025337" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" "Nucleoplasm, Centriolar satellite" Cytosol "CAB025337: , HPA005558: AB_1079175" "unprognostic (1.98e-1)" "prognostic favourable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-3)" "unprognostic (2.04e-1)" "unprognostic (9.99e-2)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.06e-1)" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" 16.0 13.7 13.5 10.4 14.3 9.1 12.4 13.2 15.1 13.1 15.7 15.4 13.8 13.6 11.0 12.7 26.3 15.1 12.7 19.7 13.9 13.7 13.2 22.0 10.8 15.5 16.7 7.4 11.8 14.3 11.1 10.2 11.5 14.3 13.9 8.8 11.8 11.3 13.9 63.9 16.8 13.8 11.6 16.5 11.3 10.6 12.2 13.8 13.1 14.5 29.1 16.1 14.5 11.2 14.6 23.7 21.3 19.8 21.0 30.8 19.6 17.2 31.7 8.8 11.7 18.1 15.5 9.4 14.7 11.0 15.1 13.6 22.5 17.4 24.6 38.8 16.3 15.5 17.4 11.5 7.5 23.8 19.1 37.2 9.4 26.6 17.5 19.4 20.2 16.0 15.6 17.0 7.9 14.3 22.7 45.6 13.1 23.9 14.1 53.4 25.6 26.7 25.6 11.0 28.7 9.8 20.7 24.2 12.6 20.5 13.8 12.7 11.9 26.0 17.6 24.4 13.1 27.3 17.8 26.6 33.3 24.1 18.8 23.2 17.9 16.1 19.8 21.3 30.8 17.0 29.3 14.6 21.5 28.3 23.7 5.7 13.5 19.1 10.9 21.0 16.6 16.3 25.4 19.6 13.5 14.3 13.2 12.8 13.9 13.7 16.7 7.4 14.3 13.8 KIAA1109 "FLJ21404, FSA, KIAA1371, Tweek" ENSG00000138688 KIAA1109 Q2LD37 4 122152333-122362758 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038076 Approved Approved Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "HPA038076: AB_10670652" "unprognostic (2.53e-1)" "unprognostic (2.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (6.62e-2)" "unprognostic (7.61e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.97e-2)" "prognostic favourable (4.33e-8)" "unprognostic (2.04e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (2.29e-2)" 18.4 17.1 25.6 18.0 34.1 42.9 26.1 33.4 34.2 22.9 18.7 24.1 17.9 15.6 20.9 25.4 12.3 16.8 16.4 15.3 25.5 22.0 24.0 17.4 19.5 14.8 26.4 26.2 34.3 16.6 68.2 33.1 14.3 33.6 19.1 18.8 22.6 16.6 21.5 40.1 23.1 20.8 18.6 29.3 20.0 15.2 20.4 24.2 15.3 25.4 12.6 13.6 18.0 18.5 3.1 2.3 7.7 3.6 1.7 3.5 0.7 16.7 5.5 12.8 8.4 21.4 27.9 6.7 7.6 14.3 7.9 8.7 4.0 8.9 8.8 4.4 18.0 6.3 7.9 9.4 12.8 6.6 5.0 9.7 10.0 7.6 11.1 9.1 5.4 16.0 11.3 9.4 13.0 16.7 6.3 10.7 16.1 5.6 7.8 7.1 4.2 6.1 4.5 17.8 2.2 13.8 12.7 7.5 6.7 4.8 5.5 10.7 6.0 7.5 22.3 9.8 9.7 8.0 7.7 10.4 6.7 6.4 10.4 8.0 7.1 3.3 1.4 7.7 3.3 3.6 3.5 2.5 2.3 2.3 1.4 3.1 2.0 2.3 6.6 1.7 1.7 2.3 2.9 0.7 25.6 34.1 33.4 34.2 25.5 22.0 26.4 26.2 33.6 24.2 KIFC3 ENSG00000140859 "Kinesin family member C3" Q9BVG8 16 57758217-57863053 "Cancer-related genes, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 55.9;HMC-1: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021240 Uncertain "HPA021240: AB_1852509" "unprognostic (1.53e-1)" "unprognostic (3.10e-3)" "unprognostic (8.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "unprognostic (2.29e-1)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (7.66e-3)" "unprognostic (1.59e-2)" "unprognostic (2.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" "unprognostic (4.33e-2)" 11.0 10.3 10.0 12.9 14.5 7.7 13.0 5.3 16.2 7.3 16.6 18.4 4.6 15.2 8.6 18.8 11.5 5.8 10.9 21.6 10.0 11.5 36.3 36.3 16.8 6.5 19.3 10.3 9.7 29.0 20.2 12.6 20.5 18.7 10.1 6.8 30.3 8.1 11.9 6.3 40.2 31.0 9.9 13.7 8.4 8.4 24.7 18.7 0.9 26.6 7.4 6.1 10.5 13.4 2.3 0.5 2.3 1.6 0.3 4.6 1.5 10.5 55.9 4.3 8.9 1.9 2.8 7.4 13.3 17.2 20.3 9.7 15.1 16.6 1.6 17.2 8.5 11.4 0.4 12.2 7.1 0.6 2.7 8.8 17.5 19.3 7.9 1.4 54.9 4.0 4.4 10.7 10.9 5.3 15.5 2.3 7.5 7.8 1.9 15.5 2.7 12.0 1.2 6.1 8.4 13.0 5.7 1.4 3.1 22.6 16.2 14.1 4.9 6.7 10.5 26.4 18.7 12.2 18.3 1.9 1.0 1.3 13.4 1.0 24.8 0.6 0.7 0.6 4.6 0.0 0.7 2.3 2.0 4.2 0.5 2.0 1.0 1.3 2.3 0.3 1.6 0.5 0.2 1.5 10.0 14.5 5.3 16.2 10.0 11.5 19.3 10.3 18.7 18.7 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 65.5" "Group enriched" "Detected in some" 13 "HEL: 47.7;HMC-1: 100.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7" "Group enriched" "Detected in many" 6 "granulocytes: 12.7;NK-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" 48000000 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: , CAB072867: , HPA004471: AB_1078431, HPA073252: " "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favourable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 8.1 1.6 9.5 6.6 11.8 3.7 65.5 18.3 12.0 12.1 10.3 6.5 10.2 5.8 8.9 4.2 9.9 2.5 15.5 2.4 36.0 4.4 9.4 1.1 13.8 3.8 3.6 6.0 28.5 2.1 1.3 2.3 6.2 5.7 9.6 10.4 20.7 12.9 6.9 1.3 14.6 8.9 10.2 3.9 3.2 12.8 4.0 4.5 0.4 28.9 4.3 4.9 9.8 12.5 0.0 1.8 12.7 0.9 9.7 1.9 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.6 0.9 2.5 3.2 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 2.1 0.0 1.1 47.7 0.0 0.0 0.0 0.0 100.2 0.0 0.0 0.0 0.0 5.6 0.6 0.1 0.0 0.0 0.2 0.4 1.3 0.0 0.1 0.0 0.0 0.0 4.7 1.2 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 12.7 0.0 10.0 0.1 0.0 1.9 0.0 0.3 0.7 1.8 0.0 0.0 0.0 0.8 9.7 0.9 0.0 0.0 0.1 9.5 11.8 18.3 12.0 36.0 4.4 3.6 6.0 5.7 4.5 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: " "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 14.4 11.3 17.7 17.0 19.2 28.6 16.8 43.8 21.2 17.3 14.6 19.8 18.1 8.5 21.8 17.1 10.6 15.7 14.1 10.2 17.3 13.4 13.1 9.3 15.3 19.6 16.6 18.7 35.6 16.8 28.9 21.8 10.2 15.4 15.6 12.4 14.4 14.2 19.2 11.1 16.8 14.2 15.2 12.1 15.7 12.3 7.9 23.4 16.6 16.6 7.8 19.4 18.8 24.6 6.7 3.5 8.3 2.0 6.5 5.3 0.8 11.9 5.5 14.9 11.2 9.1 10.9 4.4 5.4 7.8 5.7 6.6 11.1 8.7 14.7 11.1 7.9 10.4 15.8 5.9 11.3 16.2 6.1 28.8 5.1 6.0 5.1 17.2 5.6 5.2 6.1 12.4 16.7 8.8 18.7 12.6 7.1 9.3 11.4 10.1 9.0 8.2 8.7 14.3 4.9 8.4 9.0 12.3 8.0 13.5 4.4 2.8 7.6 5.8 13.0 9.8 8.8 7.1 9.6 3.7 2.8 9.9 3.7 12.7 5.8 8.3 2.0 4.6 5.3 1.3 4.3 6.2 4.8 4.6 0.8 6.7 4.9 4.8 1.3 6.5 1.4 3.5 3.9 0.8 17.7 19.2 43.8 21.2 17.3 13.4 16.6 18.7 15.4 23.4 KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35718019-35738878 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006487: AB_1080587" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.41e-2)" "unprognostic (7.95e-2)" "unprognostic (9.92e-2)" "unprognostic (3.53e-3)" "unprognostic (2.33e-2)" "unprognostic (4.57e-2)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (3.13e-3)" "unprognostic (2.63e-3)" "unprognostic (9.47e-3)" "unprognostic (2.10e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" 10.2 9.3 11.4 14.2 13.1 18.4 10.4 23.9 11.4 10.0 12.0 14.2 12.9 13.8 13.0 7.1 11.4 11.6 12.6 7.5 11.0 5.3 9.9 8.9 10.6 14.7 14.7 6.8 15.3 19.6 10.8 13.3 9.3 11.2 12.1 5.6 13.8 14.7 10.0 13.3 19.9 12.3 12.2 12.4 15.8 12.1 21.5 14.9 14.1 14.9 7.0 14.2 12.4 14.2 0.4 0.7 3.2 0.7 2.1 0.7 0.2 11.3 19.2 8.9 9.7 4.6 4.5 9.3 5.5 4.0 5.6 4.3 12.8 5.8 10.1 8.7 4.6 7.5 8.0 4.7 2.5 15.0 8.9 18.2 9.0 6.4 4.5 11.1 20.9 6.1 6.4 5.7 6.3 5.5 15.2 12.7 3.6 11.6 9.4 9.6 8.2 6.8 14.8 5.8 5.5 3.1 10.1 10.1 8.1 8.4 13.6 5.8 8.3 11.8 7.6 11.3 12.2 7.5 11.7 17.5 10.7 8.1 6.1 10.3 7.8 1.0 0.7 0.6 0.7 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.4 3.2 2.1 0.3 0.7 0.2 0.2 11.4 13.1 23.9 11.4 11.0 5.3 14.7 6.8 11.2 14.9 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436005 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm Nucleoplasm "HPA074736: " "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favourable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 13.9 12.6 11.7 16.7 18.6 29.7 14.5 24.8 14.1 18.4 12.6 15.5 21.4 9.7 20.2 20.6 14.4 12.8 12.7 10.8 13.4 9.5 10.3 11.4 13.0 12.1 17.7 9.4 18.8 18.4 18.8 18.9 38.0 12.6 14.0 11.8 12.6 15.8 22.9 30.3 25.2 13.1 13.6 16.0 14.6 14.9 13.6 19.6 22.6 16.9 9.3 16.8 17.8 31.6 5.6 3.5 16.1 3.9 5.5 2.9 0.6 9.5 4.8 9.0 9.5 16.2 9.8 10.5 5.0 3.8 4.0 4.9 9.1 5.8 15.2 7.3 9.1 5.5 9.6 7.3 6.7 9.6 4.9 9.0 7.2 6.3 7.9 15.3 11.1 8.2 10.1 5.7 7.6 5.7 14.5 13.2 8.7 13.3 11.0 13.9 5.4 4.8 7.4 8.1 7.9 6.9 9.9 13.1 10.3 8.2 14.7 5.4 4.8 12.5 7.2 6.7 3.5 7.1 7.1 13.8 6.7 16.4 8.7 12.5 6.8 8.8 3.5 4.3 2.1 2.2 2.9 5.6 1.7 1.7 1.7 3.8 2.7 1.8 16.1 5.5 3.9 3.5 1.3 0.6 11.7 18.6 24.8 14.1 13.4 9.5 17.7 9.4 12.6 19.6 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49059774 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 12.1 7.6 4.9 6.7 10.8 26.1 6.8 11.7 10.5 9.5 6.5 5.8 13.0 5.5 15.7 7.4 8.8 8.9 5.8 9.1 6.1 3.5 6.2 6.5 22.9 9.6 6.7 3.3 9.7 11.6 13.3 9.2 12.9 13.7 6.7 6.6 9.8 7.6 8.0 16.1 13.6 9.4 7.1 9.1 13.6 8.3 7.3 5.7 6.2 11.0 6.1 7.6 7.0 6.3 2.0 2.2 5.9 0.5 1.5 0.8 0.6 17.0 16.2 16.4 13.2 17.0 11.4 17.6 9.0 9.4 11.7 6.3 28.4 7.2 17.7 11.7 12.6 11.6 21.6 10.0 9.8 10.3 17.3 22.5 16.9 15.2 11.7 26.7 22.6 9.7 14.3 16.4 17.0 17.4 28.2 9.8 13.2 18.7 13.2 24.9 15.5 14.0 19.9 10.1 6.4 9.8 18.9 13.7 11.6 13.9 13.7 9.5 13.6 23.4 23.1 9.2 16.5 8.1 15.1 14.0 9.0 17.2 10.6 13.8 6.9 0.6 0.5 3.0 0.8 0.2 0.4 0.3 0.3 0.5 0.3 2.0 0.3 0.8 5.9 1.5 0.1 2.2 0.0 0.6 4.9 10.8 11.7 10.5 6.1 3.5 6.7 3.3 13.7 5.7 KRAS "KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25204789-25250936 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049830 Approved 5800000 "HPA049830: " "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (3.74e-2)" "unprognostic (1.79e-1)" "unprognostic (2.39e-1)" "prognostic unfavourable (3.59e-4)" "unprognostic (6.42e-2)" "prognostic favourable (2.75e-5)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.81e-2)" "unprognostic (9.97e-2)" 11.7 9.9 14.4 15.5 19.5 24.1 10.6 21.1 25.6 10.3 26.2 7.3 7.9 16.1 11.3 7.7 25.1 10.1 13.9 9.3 13.6 16.6 14.0 17.9 14.9 15.1 11.6 15.8 13.1 13.6 12.7 9.8 15.7 21.1 12.1 28.1 9.8 16.2 9.8 10.0 14.0 23.7 17.2 11.3 15.7 23.6 7.8 9.5 18.5 11.1 10.6 16.3 16.8 14.3 10.0 7.1 20.8 18.9 9.4 13.8 5.0 7.2 7.4 16.6 9.4 6.2 8.4 33.3 7.4 9.4 7.8 9.3 25.7 16.8 16.8 4.5 12.9 8.0 19.4 8.1 14.8 11.4 6.7 15.8 7.9 6.3 6.5 14.8 12.1 7.8 11.1 9.4 8.4 11.3 11.2 8.0 11.5 6.2 20.4 22.5 36.4 3.0 17.6 17.6 24.1 11.5 12.9 5.1 14.2 8.9 11.7 8.9 13.0 10.7 13.0 8.8 11.6 16.4 9.2 7.0 11.8 18.2 6.7 8.7 6.3 20.8 7.8 12.4 11.9 14.4 7.5 10.0 10.4 13.0 7.1 8.6 13.8 12.1 19.0 9.4 18.9 7.1 6.7 5.0 14.4 19.5 21.1 25.6 13.6 16.6 11.6 15.8 21.1 9.5 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 188.6;lymphoid tissue: 118.2" "Cell line enhanced" "Detected in many" "Daudi: 82.6;HDLM-2: 75.5;HL-60: 80.2;HMC-1: 85.1;THP-1: 74.8;U-698: 106.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" 2200000000 "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 57.1 10.0 5.6 44.3 9.4 71.2 8.7 3.9 4.6 3.6 6.2 4.5 5.0 4.5 5.3 43.1 6.2 8.3 8.9 5.5 4.3 3.8 7.2 12.2 33.7 59.1 12.0 1.0 5.7 3.9 0.1 2.8 24.7 7.7 21.5 8.1 5.5 9.5 2.5 3.5 6.8 21.7 6.5 11.9 112.9 6.1 8.2 9.2 118.2 4.5 4.1 68.7 14.0 7.1 25.4 79.3 133.5 127.6 43.2 67.2 188.6 3.3 0.0 0.1 0.0 0.0 0.0 40.1 0.0 0.1 0.3 0.2 22.1 0.1 82.6 17.6 0.0 0.1 0.0 0.0 0.3 75.5 19.6 17.8 0.0 0.0 0.0 80.2 85.1 0.2 0.0 0.1 0.1 0.0 9.3 55.0 0.0 0.1 56.8 55.5 0.0 0.8 42.3 0.1 59.0 0.0 22.8 0.1 0.7 0.1 8.8 0.6 0.4 74.8 0.2 2.1 1.3 0.1 2.4 13.1 27.3 106.3 1.6 48.9 0.3 57.1 96.6 54.3 67.2 127.6 60.8 25.4 40.4 55.5 79.3 18.3 25.2 42.3 133.5 43.2 118.1 20.8 40.5 188.6 5.6 9.4 3.9 4.6 4.3 3.8 12.0 1.0 7.7 9.2 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.8" "Cell line enhanced" "Detected in many" "K-562: 46.1;RPTEC TERT1: 22.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA030899 Approved Supported "Secreted to blood" 8235000 8300000 "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 15.9 5.5 3.8 3.7 4.3 3.3 23.5 2.5 3.9 15.0 9.2 5.6 5.4 3.2 20.6 7.3 10.9 11.7 10.1 9.2 4.3 4.9 14.6 82.8 20.3 9.0 4.9 3.3 18.4 16.7 3.9 13.1 12.8 8.2 10.8 4.1 18.1 12.0 5.7 5.6 10.2 7.3 12.9 7.0 6.4 11.9 6.6 3.1 1.9 13.1 11.2 6.9 13.6 8.6 0.6 1.8 6.9 1.9 1.1 2.3 1.8 1.3 0.8 1.1 1.2 5.0 4.6 3.8 5.9 3.4 2.0 1.9 0.6 3.2 0.5 4.4 7.4 1.1 0.9 5.1 5.5 6.9 1.5 7.7 3.5 0.1 3.0 0.5 0.6 13.0 3.0 1.2 4.6 5.8 46.1 0.9 9.5 0.3 0.6 0.1 1.8 0.1 0.1 0.9 0.3 22.3 0.6 0.7 11.3 1.4 0.6 1.6 2.1 2.0 2.2 2.1 4.3 0.4 3.2 1.3 0.8 0.2 4.4 2.2 2.0 6.9 1.9 2.8 1.3 1.5 1.3 0.6 1.1 1.1 1.8 0.3 0.9 1.5 1.1 1.1 1.7 1.2 2.3 1.8 3.8 4.3 2.5 3.9 4.3 4.9 4.9 3.3 8.2 3.1 LIFR CD118 ENSG00000113594 "LIF receptor alpha" P42702 5 38474963-38608354 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 39.8;HHSteC: 17.0;SCLC-21H: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004478, CAB010252" Approved "Nuclear speckles,Golgi apparatus" "Intracellular and membrane" 74000 "Nuclear speckles" "Golgi apparatus" "CAB010252: AB_2128043, HPA004478: " "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favourable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favourable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 35.3 14.7 15.8 8.2 19.2 0.5 33.9 10.1 21.3 27.7 10.4 25.3 22.8 4.9 34.8 14.8 10.4 26.0 10.2 16.3 19.1 11.0 20.3 23.9 21.7 20.2 24.3 11.8 17.9 17.8 13.5 12.5 41.5 23.4 23.6 7.5 17.1 24.9 24.7 24.0 10.5 11.7 26.9 21.4 22.5 18.8 9.3 25.3 4.7 31.4 7.3 8.1 13.6 15.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 2.2 39.8 3.0 11.2 12.4 0.3 3.3 1.9 2.7 1.6 0.4 2.1 0.0 0.5 4.7 0.3 2.6 0.9 4.6 0.0 3.6 0.0 4.2 1.5 17.0 0.0 0.2 10.4 0.7 6.5 0.7 3.7 1.0 6.4 3.3 0.5 0.0 0.1 1.0 7.1 0.0 8.4 0.0 2.6 1.0 26.1 3.2 13.7 0.6 0.0 0.9 0.0 0.7 4.3 8.5 10.1 2.0 0.0 0.0 0.0 7.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 19.2 10.1 21.3 19.1 11.0 24.3 11.8 23.4 25.3 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 127.8;urinary bladder: 105.1" "Cell line enhanced" "Detected in many" "Daudi: 28.8;EFO-21: 35.8;U-698: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 18.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Enhanced "Focal adhesion sites,Cytosol" 520000 "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 19.6 4.2 2.7 29.5 2.8 3.1 12.5 3.0 2.7 42.2 29.9 2.1 19.6 5.0 68.6 14.9 59.7 10.0 37.9 9.3 2.6 2.8 10.9 5.3 11.4 6.0 2.8 1.6 26.1 4.4 4.7 3.2 5.2 3.0 37.7 12.8 8.5 7.0 28.4 11.6 5.9 17.2 127.8 3.2 9.5 12.1 30.7 1.5 5.1 5.4 4.2 7.8 105.1 38.3 5.9 4.9 18.0 4.5 4.3 5.0 1.4 7.5 7.0 5.1 3.4 11.1 11.4 5.5 4.9 6.3 3.6 2.4 12.6 3.6 28.8 35.8 11.2 3.2 1.5 3.3 9.1 3.1 1.7 1.4 5.4 3.3 4.7 0.6 1.7 8.1 4.7 8.1 7.0 6.1 0.0 0.6 6.3 2.4 1.4 0.6 2.0 2.3 1.8 3.8 0.1 4.0 8.0 0.3 0.0 10.6 3.5 6.0 2.7 2.4 13.1 8.4 6.5 6.0 12.2 0.0 1.1 59.7 4.2 1.3 7.6 0.8 4.5 1.9 5.0 4.2 3.2 2.9 4.3 3.6 2.4 5.9 2.3 2.9 18.0 4.3 4.0 4.9 1.6 1.4 2.7 2.8 3.0 2.7 2.6 2.8 2.8 1.6 3.0 1.5 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell line enhanced" "Detected in some" "A549: 9.7;ASC TERT1: 10.0;BJ hTERT+: 5.6;RPTEC TERT1: 10.7" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favourable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.7 0.1 0.0 3.9 10.0 0.1 2.1 5.6 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.4 0.0 0.7 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 0.6 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.6 0.0 0.2 2.7 2.8 2.2 1.4 1.1 1.1 1.2 0.7 0.0 0.0 0.0 2.3 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111831 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 344.8" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" 59000000000 "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavourable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 44.8 25.3 0.8 15.1 0.7 0.0 19.7 0.7 0.7 56.7 26.9 0.7 28.1 5.1 64.8 77.8 28.1 12.2 76.6 48.8 0.8 0.7 26.9 6.4 77.1 32.0 0.9 0.6 73.0 9.1 0.7 2.7 344.8 2.8 77.4 13.3 1.4 5.6 9.9 9.1 8.3 24.0 48.7 4.0 1.3 8.2 30.9 0.3 1.7 18.1 32.3 11.5 65.3 20.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 22.5 11.1 0.0 36.9 182.3 1.5 2.3 0.0 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.3 0.0 17.6 0.0 0.0 15.2 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.4 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.7 0.7 0.8 0.7 0.9 0.6 2.8 0.3 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879813-56014168 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.9" "Cell line enhanced" "Detected in many" "HEL: 56.8;HMC-1: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" 11000000 "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavourable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 8.8 6.8 4.5 34.0 6.3 33.6 11.1 9.5 4.1 5.3 10.5 5.8 7.2 15.6 3.4 7.8 7.2 6.7 13.7 8.9 4.8 3.6 6.1 13.8 34.6 70.9 7.7 2.1 5.3 9.8 3.1 4.9 19.1 5.6 5.7 6.6 6.3 14.9 8.5 2.7 3.4 16.2 6.6 8.5 69.4 7.4 3.6 5.1 3.8 9.4 5.3 25.8 10.7 7.5 8.4 9.2 36.8 26.5 1.9 0.9 2.7 12.6 7.5 1.7 0.3 0.1 0.0 13.7 9.7 14.2 6.1 4.3 5.2 4.4 12.2 4.3 3.8 5.9 7.1 7.2 5.2 19.8 7.1 56.8 2.3 1.8 1.9 5.7 57.7 0.3 2.5 0.1 4.4 8.2 30.0 26.5 0.9 0.7 0.0 6.0 10.9 0.8 0.9 2.8 1.5 3.9 6.0 1.1 22.0 4.8 0.0 2.0 1.1 13.4 9.6 0.0 2.8 0.0 4.4 8.9 3.2 27.6 0.6 11.3 0.4 2.1 7.2 12.3 0.9 16.8 0.7 8.2 0.2 0.3 6.4 8.4 0.1 0.4 36.8 1.9 26.5 9.2 0.0 2.7 4.5 6.3 9.5 4.1 4.8 3.6 7.7 2.1 5.6 5.1 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982013-20999038 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: , HPA071248: " "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavourable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 21.2 16.9 17.3 15.6 17.4 10.3 17.9 20.7 24.7 18.5 18.3 25.3 20.6 18.9 24.9 14.0 16.5 18.3 21.2 15.8 15.4 10.9 17.2 13.1 16.2 12.8 19.6 16.5 21.7 16.2 24.9 26.0 18.8 19.0 16.9 12.9 18.9 17.5 18.0 17.2 15.0 15.7 21.9 14.0 19.3 14.5 10.8 19.2 10.8 19.6 12.6 12.5 18.5 16.4 1.6 2.2 0.2 3.4 1.8 3.0 1.5 6.2 5.1 7.6 9.2 17.6 12.2 6.2 12.8 9.0 7.3 10.0 3.0 2.6 6.6 4.8 14.2 8.4 5.7 10.5 2.9 12.3 13.3 7.1 6.7 4.4 9.4 3.8 9.4 11.2 5.3 9.2 6.7 14.1 29.4 11.5 8.2 3.8 6.8 3.6 2.4 5.6 8.0 11.1 2.6 5.7 8.4 7.5 11.2 6.9 12.1 7.5 5.6 7.1 12.6 17.0 8.7 7.7 6.9 5.0 4.4 2.0 7.7 3.7 8.2 0.0 2.5 0.2 3.0 3.1 1.6 1.6 1.5 2.8 2.2 1.0 2.1 1.5 0.1 1.8 3.4 1.2 0.5 1.5 17.3 17.4 20.7 24.7 15.4 10.9 19.6 16.5 19.0 19.2 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 17.9 15.5 20.4 10.5 11.3 14.7 13.0 12.3 16.2 14.0 13.4 9.2 6.2 7.5 10.0 19.1 12.1 17.7 17.1 21.1 13.2 20.8 8.3 9.1 17.3 13.3 7.9 12.6 12.1 17.0 16.4 17.2 12.7 8.8 4.4 17.6 6.7 9.6 7.4 11.9 7.6 11.8 22.9 5.1 19.2 11.6 4.1 12.1 14.2 7.6 11.8 9.6 5.8 11.6 6.9 10.7 9.5 14.5 8.7 9.7 5.9 13.0 6.3 10.0 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.0;THP-1: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol Cytosol "CAB004500: AB_627926, HPA046509: " "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.4 3.9 6.2 4.1 1.0 0.8 10.4 1.2 1.7 3.9 5.5 18.4 4.9 5.8 0.4 1.5 3.4 5.1 2.3 5.4 2.0 2.2 3.2 1.7 8.6 2.5 5.1 9.0 1.0 2.5 1.2 1.9 1.7 2.8 10.5 1.0 2.8 3.5 6.9 2.8 0.5 5.6 4.4 19.9 6.8 6.8 2.6 27.0 3.8 4.8 11.0 13.2 25.2 4.9 0.3 3.3 1.4 2.3 7.7 3.9 11.1 0.6 3.0 6.6 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm Nucleoplasm "CAB007764: AB_562314, HPA035410: , HPA035411: " "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.1 7.6 9.7 9.4 18.6 15.0 4.4 10.0 11.0 12.5 10.1 3.5 2.1 10.9 7.1 19.6 3.8 6.3 7.1 7.9 9.5 13.9 8.9 10.3 4.9 9.7 6.8 9.5 10.7 4.9 15.5 8.2 30.3 5.4 14.5 9.9 7.1 12.2 7.1 6.0 8.1 6.5 24.8 7.1 4.5 4.6 5.0 11.9 6.8 8.2 8.3 8.2 6.8 27.2 32.0 8.5 17.3 12.1 14.4 14.6 4.0 6.9 5.5 8.3 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.6 5.3 10.1 8.6 6.3 7.4 6.5 5.3 4.7 6.1 6.5 7.5 3.4 9.6 3.8 13.5 11.7 10.3 10.6 7.5 7.0 8.4 12.5 4.9 7.4 4.8 13.0 6.1 4.6 12.3 6.4 5.8 7.9 31.6 11.1 6.5 4.8 8.7 6.6 6.1 8.2 9.6 9.3 7.6 5.6 3.4 5.8 5.2 9.9 10.6 0.9 4.3 15.9 7.4 7.5 9.6 6.9 25.0 6.5 5.2 8.8 8.8 13.4 7.8 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell line enhanced" "Detected in many" "SCLC-21H: 38.6" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332" Enhanced "Plasma membrane" "Plasma membrane" "HPA058921: , HPA070332: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favourable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 3.0 12.8 33.3 2.1 29.6 1.4 2.7 24.9 73.5 3.1 1.9 4.6 0.1 1.6 4.9 3.1 2.1 6.6 3.0 2.9 38.1 22.3 5.1 2.7 2.6 1.0 28.0 18.9 4.4 26.4 14.7 24.8 1.6 23.5 4.9 1.5 4.5 4.8 5.0 1.7 1.7 2.0 4.4 44.4 1.7 3.8 10.8 4.8 0.0 3.9 0.5 0.9 2.0 0.4 0.4 0.4 2.1 0.9 2.6 0.2 0.0 0.0 3.5 4.7 13.1 1.8 0.9 0.1 2.5 2.2 5.0 3.6 3.0 0.5 0.2 1.2 2.9 2.8 5.0 2.3 2.2 1.9 6.5 0.0 4.4 2.0 1.6 0.2 2.2 1.2 0.5 3.2 0.6 1.1 5.4 0.8 1.4 1.8 0.1 0.3 12.5 5.2 0.3 7.7 0.1 2.3 0.0 38.6 14.4 4.1 3.4 4.7 5.5 0.2 1.0 6.4 9.8 9.5 4.5 0.5 0.6 0.2 4.0 0.1 1.9 2.1 0.9 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.4 0.1 0.2 1.8 2.6 0.0 0.4 0.1 0.0 33.3 29.6 24.9 41.7 38.1 22.3 28.0 18.9 23.5 4.8 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavourable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 15.2 12.4 12.5 9.6 16.4 23.6 13.9 16.3 11.8 15.1 16.9 14.2 5.0 23.9 7.7 19.9 7.6 15.1 9.3 16.0 11.5 8.1 10.8 14.0 13.0 14.3 5.8 13.9 18.1 12.1 25.3 20.3 14.1 8.3 7.3 18.0 10.4 8.4 6.0 10.3 14.2 12.4 21.0 4.5 7.8 8.3 17.5 10.4 19.2 25.1 8.2 11.4 5.7 13.7 29.3 18.9 15.3 16.1 10.0 8.9 8.7 19.6 7.9 12.1 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.3;bone marrow: 19.1;brain: 27.4" "Cell line enhanced" "Detected in some" "HL-60: 40.7;HMC-1: 12.5;K-562: 18.1;MCF7: 13.2;NB-4: 28.4;SCLC-21H: 12.4;THP-1: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 19.4;NK-cell: 29.3" "Group enriched" "Detected in many" 54 "NK-cells: 29.3;T-cells: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favourable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 11.2 1.6 22.1 6.8 18.1 19.1 2.2 1.5 27.4 1.5 2.3 1.7 0.0 7.0 1.2 0.4 1.1 4.7 5.1 1.7 25.1 10.0 1.1 2.8 7.3 9.6 7.0 11.0 1.0 1.6 0.1 1.4 1.4 6.1 1.2 1.4 0.6 3.8 1.0 0.8 1.6 6.7 1.1 2.8 14.8 4.1 2.1 1.3 3.5 0.9 0.0 4.5 2.4 0.7 0.4 0.3 0.4 0.0 29.3 19.4 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 4.1 5.4 0.1 0.0 0.0 7.0 4.5 0.5 1.1 0.0 40.7 12.5 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 13.2 0.1 28.4 3.3 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 10.7 1.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 13.2 0.0 2.5 12.2 0.3 0.4 1.2 7.1 0.4 29.3 0.0 0.1 0.1 2.7 22.1 18.1 1.5 27.4 25.1 10.0 7.0 11.0 6.1 1.3 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavourable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favourable (2.12e-4)" "unprognostic (6.03e-2)" 33.4 25.5 31.3 31.5 38.6 68.7 25.8 59.0 38.2 34.6 29.4 37.2 26.3 31.5 34.3 24.0 47.6 38.2 27.9 30.1 29.9 28.4 26.3 21.8 31.4 43.4 37.1 21.6 39.7 20.0 17.4 23.7 30.2 32.7 31.9 25.0 26.8 33.6 37.7 27.8 32.1 40.2 30.7 34.8 42.9 24.8 15.7 40.9 41.3 30.2 22.5 40.7 35.1 40.7 18.7 19.1 87.5 23.6 19.2 30.0 44.8 28.3 11.1 6.8 11.0 18.0 14.1 8.9 10.0 15.3 12.5 15.4 7.1 19.9 23.6 8.4 12.0 14.1 17.1 13.9 9.4 23.8 10.4 36.7 7.3 7.8 21.1 13.8 92.4 16.8 9.9 11.5 12.7 13.8 17.2 9.6 12.6 15.7 31.9 47.6 9.1 18.2 18.1 10.8 10.6 11.5 9.5 14.7 9.6 13.1 14.0 12.8 13.7 17.7 17.2 11.5 13.9 10.6 8.0 11.8 10.0 14.9 14.3 13.3 11.4 87.5 23.6 80.6 21.7 20.1 23.7 18.7 25.4 22.1 19.1 17.6 26.6 22.3 49.5 19.2 17.4 18.3 30.0 44.8 31.3 38.6 59.0 38.2 29.9 28.4 37.1 21.6 32.7 40.9 MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717889 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 15.4;AN3-CA: 12.1;HEK 293: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006915 Enhanced Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA006915: AB_1853669" "unprognostic (8.52e-2)" "unprognostic (4.32e-1)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (4.39e-3)" "unprognostic (3.23e-1)" 10.8 3.6 5.7 9.5 5.9 4.9 5.5 10.2 8.0 6.9 6.3 8.5 3.8 3.8 9.9 5.1 3.7 8.3 5.0 5.0 5.2 2.4 5.1 6.2 5.1 5.4 4.9 3.7 11.3 5.7 3.1 12.5 3.1 6.0 6.4 2.9 9.4 5.5 3.5 11.1 11.7 6.4 6.1 5.5 7.1 7.7 26.7 5.3 11.4 11.9 2.4 13.0 5.2 5.4 2.0 1.8 0.4 0.2 3.8 1.2 0.3 15.4 1.0 1.2 12.1 3.9 3.8 1.0 1.3 0.7 2.7 1.0 1.0 1.7 2.6 6.6 7.7 1.6 2.4 4.4 2.5 2.1 29.3 1.9 2.9 0.6 0.4 1.1 1.4 0.9 0.9 4.1 1.9 0.4 3.8 2.9 0.4 1.4 0.7 0.2 0.8 0.8 2.2 1.3 2.9 4.5 3.3 2.6 1.3 0.6 3.1 0.5 2.8 2.2 0.9 1.0 1.5 2.0 1.4 1.9 7.2 6.7 0.3 4.3 2.1 0.4 0.1 0.3 1.1 0.2 0.9 0.8 0.9 1.2 0.2 2.0 1.0 0.8 0.1 3.8 0.1 1.8 0.0 0.3 5.7 5.9 10.2 8.0 5.2 2.4 4.9 3.7 6.0 5.3 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663618 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 21.5;RPTEC TERT1: 27.6;RT4: 43.5;TIME: 20.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046537 Supported Supported "Nuclear speckles" "Nuclear speckles" "HPA046537: " "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavourable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 25.9 0.7 3.3 5.7 5.6 0.3 9.1 3.4 5.3 13.5 13.9 1.6 22.1 11.2 15.4 5.7 10.4 14.3 8.1 8.2 3.3 2.9 32.2 2.6 30.0 1.5 4.6 1.4 6.2 27.8 1.1 5.3 10.0 4.7 9.3 17.5 4.2 5.9 25.3 16.0 2.3 5.9 5.6 5.8 6.4 39.4 2.7 3.5 0.2 4.7 3.3 3.5 18.1 18.5 0.3 0.0 0.6 1.5 1.8 1.0 0.0 9.6 0.1 0.2 0.0 1.3 1.0 0.1 1.3 1.5 0.5 0.8 3.8 9.9 0.0 15.2 0.2 5.1 4.0 5.9 1.1 0.5 6.3 6.1 1.6 0.1 0.1 0.0 1.9 2.1 0.8 0.3 4.5 21.5 4.6 0.7 3.8 1.0 0.0 0.0 0.2 2.5 3.6 4.9 0.2 27.6 43.5 0.3 1.1 0.4 2.5 0.1 2.9 0.0 20.4 3.8 2.5 1.0 6.4 0.5 0.1 0.3 1.9 0.0 0.5 0.3 0.0 0.6 0.4 0.2 1.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 1.8 1.5 0.0 0.1 0.0 3.3 5.6 3.4 5.3 3.3 2.9 4.6 1.4 4.7 3.5 MED12 "CAGH45, FGS1, HOPA, KIAA0192, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.2 31.3 12.3 15.3 14.7 16.6 18.1 18.0 15.1 16.8 12.8 19.8 21.3 10.2 21.7 16.5 13.1 17.7 14.2 12.9 12.9 8.5 13.3 9.8 14.0 15.3 15.7 10.7 28.8 14.2 20.1 17.9 23.0 11.6 16.5 11.8 18.6 14.6 20.3 14.9 17.6 14.8 16.4 11.2 27.3 14.2 15.3 12.9 33.1 17.8 12.6 15.9 15.4 16.4 4.0 5.1 9.7 3.7 5.0 7.4 3.6 8.6 10.2 16.1 9.6 11.8 10.6 23.8 6.1 8.8 9.8 7.0 12.2 8.2 11.4 8.2 10.6 8.6 18.8 7.7 7.8 11.9 14.6 18.8 23.0 16.5 9.3 17.3 16.7 12.3 8.4 12.8 14.9 15.0 17.5 19.9 9.6 14.5 18.1 9.9 9.2 13.4 17.1 18.0 8.6 7.4 17.2 9.0 10.8 14.1 7.2 8.0 8.7 8.6 13.1 10.7 12.7 9.8 4.3 9.8 5.5 8.3 6.3 9.7 7.1 9.7 3.7 7.2 5.9 3.6 5.0 4.0 4.1 5.4 3.9 4.0 4.6 3.9 7.7 5.0 2.4 5.1 7.4 3.6 12.3 14.7 18.0 15.1 12.9 8.5 15.7 10.7 11.6 12.9 MED13 "KIAA0593, THRAP1, TRAP240" ENSG00000108510 "Mediator complex subunit 13" Q9UHV7 17 61942605-62065282 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067939 Supported Nucleoplasm Nucleoplasm "HPA067939: " "unprognostic (7.26e-2)" "unprognostic (4.50e-2)" "prognostic favourable (1.43e-4)" "unprognostic (8.79e-2)" "unprognostic (1.69e-2)" "unprognostic (3.56e-1)" "unprognostic (1.33e-1)" "unprognostic (5.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (3.92e-2)" "unprognostic (2.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.21e-1)" "unprognostic (4.51e-3)" "unprognostic (2.30e-1)" 10.4 7.6 6.3 6.6 9.1 19.3 8.8 8.8 7.5 8.7 9.0 13.8 6.8 7.1 13.6 9.0 9.7 6.8 8.2 8.4 12.6 5.3 9.0 14.3 12.7 7.3 8.2 3.5 9.9 8.6 15.3 5.9 9.6 15.6 7.1 8.3 6.4 21.6 5.9 31.8 10.0 8.1 12.0 13.8 6.7 7.4 11.9 8.3 15.1 10.4 12.4 8.9 10.7 8.4 3.2 5.6 7.9 5.0 2.7 3.5 0.7 12.9 15.4 11.9 9.7 11.0 12.0 9.1 7.1 10.4 14.5 14.0 11.7 7.1 13.8 6.8 11.2 8.0 15.2 9.3 20.3 8.9 8.9 22.5 11.2 7.4 11.5 19.7 10.5 9.2 10.8 15.8 18.0 10.9 18.4 23.8 9.9 21.9 17.7 5.9 6.3 8.0 14.6 30.6 8.4 10.2 15.3 9.4 17.9 14.9 4.3 9.3 15.6 14.0 13.6 16.7 24.5 8.6 13.4 11.6 13.1 19.0 8.8 8.8 9.4 1.6 2.1 2.5 2.8 1.0 3.5 2.0 2.7 2.9 2.1 3.2 1.9 3.5 7.9 2.7 5.0 5.6 3.0 0.7 6.3 9.1 8.8 7.5 12.6 5.3 8.2 3.5 15.6 8.3 MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA046619: " "prognostic unfavourable (4.94e-4)" "unprognostic (2.92e-1)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.48e-3)" "unprognostic (7.73e-2)" "unprognostic (1.41e-1)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.22e-1)" "unprognostic (5.56e-3)" "unprognostic (1.48e-1)" 9.0 7.4 5.8 9.9 8.0 9.5 9.2 13.9 10.7 10.7 10.2 9.0 9.4 4.3 12.1 7.5 7.9 10.4 7.3 11.5 6.3 5.4 6.4 4.6 8.2 8.1 9.5 7.3 13.8 9.9 5.4 13.1 9.5 6.1 8.2 4.9 8.0 9.4 6.6 9.3 10.2 14.0 7.7 7.7 13.9 12.1 7.9 8.8 20.7 7.8 5.5 9.8 11.2 11.6 10.5 6.8 10.8 5.7 10.2 8.5 5.1 3.0 1.0 2.6 5.6 3.2 0.4 5.1 6.7 2.3 4.5 2.8 5.3 6.3 5.0 11.3 0.6 9.4 2.4 1.4 1.2 6.0 2.7 5.6 3.4 1.5 1.7 9.4 9.5 1.3 3.3 3.3 2.2 1.8 5.0 3.0 2.7 0.9 11.2 2.7 4.9 0.8 8.6 7.6 4.1 2.7 2.1 9.2 11.7 5.6 4.7 2.8 7.0 2.3 6.1 7.0 5.6 9.3 5.8 4.7 9.1 3.6 1.8 6.7 8.0 4.9 4.6 10.8 6.4 5.7 7.6 10.5 8.2 8.0 6.0 9.0 8.5 4.8 4.7 10.2 3.3 6.8 8.1 5.1 5.8 8.0 13.9 7.9 6.3 5.4 9.5 7.3 6.1 8.8 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm Nucleoplasm "CAB004499: AB_627921, HPA046597: " "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favourable (6.93e-4)" "prognostic unfavourable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 28.9 17.4 17.4 19.1 24.3 12.0 20.1 22.9 31.6 21.9 19.7 20.1 18.2 9.5 30.5 24.7 16.6 20.5 16.6 62.0 14.9 12.7 18.8 17.5 26.0 16.7 14.0 21.9 23.0 11.7 32.0 10.2 18.8 16.1 19.9 11.4 14.5 15.5 18.4 46.1 38.4 16.3 31.2 23.6 22.2 16.3 10.7 15.8 17.6 15.2 19.6 17.3 25.2 15.9 12.8 10.7 11.3 14.2 5.6 4.5 4.3 8.7 5.0 8.4 4.2 10.7 13.8 4.2 8.9 20.5 7.3 10.0 5.1 12.2 11.0 12.6 19.0 9.6 8.5 7.0 9.6 7.4 12.5 22.1 11.1 4.6 18.4 8.7 10.9 9.2 11.8 9.8 20.4 13.3 7.8 21.1 13.6 3.6 14.3 13.0 4.6 7.3 21.0 18.4 8.9 15.1 12.4 5.4 7.6 13.5 5.9 25.0 5.5 8.0 21.7 20.5 11.2 10.1 10.7 11.5 13.1 24.0 14.3 9.7 19.4 6.2 10.3 11.3 3.4 12.8 2.9 12.8 3.2 3.0 10.7 10.4 4.5 3.4 10.2 5.6 14.2 6.6 2.1 4.3 17.4 24.3 22.9 31.6 14.9 12.7 14.0 21.9 16.1 15.8 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685368-118715433 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favourable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 17.3 16.4 15.5 12.4 19.2 25.8 18.0 25.9 19.4 21.8 16.1 12.8 11.7 13.4 19.1 17.2 16.4 15.9 12.0 12.3 13.3 11.3 17.4 22.0 13.9 15.9 16.4 16.0 22.6 14.6 17.1 34.5 13.6 16.0 20.0 13.0 12.3 13.7 14.9 13.5 16.4 15.4 14.5 17.3 17.3 14.2 26.6 18.4 24.1 18.7 10.6 16.2 23.0 16.1 18.9 12.3 24.1 17.5 17.1 18.4 10.7 14.4 6.7 14.6 13.7 9.2 11.7 10.7 12.9 9.9 9.8 11.3 9.6 17.3 16.4 7.7 9.0 7.1 12.4 10.6 12.6 12.9 7.5 13.7 8.4 10.6 10.5 22.1 16.4 10.3 12.3 11.3 7.5 8.8 14.6 14.0 13.3 9.7 21.6 18.6 12.5 5.8 12.4 18.3 8.3 10.6 9.6 12.0 13.5 9.1 16.9 12.3 7.7 21.1 11.9 14.2 13.0 12.6 10.2 11.8 12.2 18.7 10.1 12.4 11.5 24.1 10.6 22.3 14.7 15.6 16.6 18.9 15.4 15.1 12.3 18.1 18.4 16.6 8.5 17.1 17.5 9.8 16.2 10.7 15.5 19.2 25.9 19.4 13.3 11.3 16.4 16.0 16.0 18.4 MLLT10 AF10 ENSG00000078403 "MLLT10, histone lysine methyltransferase DOT1L cofactor" P55197 10 21524675-21743630 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 71.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005747 Enhanced Supported Nucleoplasm Nucleoplasm "HPA005747: AB_1079393" "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (1.31e-2)" "prognostic favourable (8.75e-4)" "unprognostic (1.03e-3)" "unprognostic (9.56e-3)" "unprognostic (9.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.69e-2)" "unprognostic (7.85e-2)" "unprognostic (6.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" 16.3 12.1 11.7 18.4 14.3 21.9 12.8 25.4 13.6 19.0 17.0 12.0 13.6 8.5 26.3 12.8 14.7 14.5 13.7 15.8 10.2 8.5 12.3 13.5 12.3 11.6 10.5 9.9 21.4 12.3 16.6 23.2 20.3 11.8 12.6 11.3 14.6 13.2 16.3 13.4 18.7 12.1 18.7 11.2 10.6 11.4 71.2 14.3 14.6 18.1 9.7 15.2 18.5 19.6 5.5 6.9 12.0 6.8 5.3 7.2 2.8 14.3 12.2 18.9 13.1 12.0 15.1 20.7 9.1 5.8 11.4 11.2 13.0 15.4 17.2 5.1 10.1 13.5 20.8 12.2 11.5 11.9 12.0 26.6 10.6 18.7 14.8 0.6 17.2 11.2 14.6 9.5 11.0 15.1 28.4 13.4 9.0 11.1 20.7 12.5 7.7 3.9 18.0 10.1 14.4 11.0 6.8 6.6 18.4 12.1 14.5 20.4 6.8 18.5 13.6 7.2 12.6 14.3 9.0 11.7 13.4 19.2 8.3 10.3 5.5 10.6 6.8 12.0 5.3 4.6 5.2 5.0 6.2 5.7 5.6 5.5 7.2 6.7 5.8 5.3 5.2 6.9 4.6 2.8 11.7 14.3 25.4 13.6 10.2 8.5 10.5 9.9 11.8 14.3 MLLT3 "AF-9, AF9, YEATS3" ENSG00000171843 "MLLT3, super elongation complex subunit" P42568 9 20341665-20622543 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 14.4" "Group enriched" "Detected in many" 5 "NK-cells: 3.8;T-cells: 14.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001824 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA001824: AB_1079394" "unprognostic (3.31e-1)" "unprognostic (2.22e-1)" "unprognostic (1.23e-3)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (3.83e-2)" "unprognostic (1.01e-3)" "unprognostic (2.12e-1)" "unprognostic (3.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-2)" "prognostic favourable (1.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.81e-2)" "unprognostic (1.40e-2)" "unprognostic (1.68e-1)" 8.6 17.3 18.0 10.4 25.8 19.7 11.4 34.6 20.3 12.3 20.9 7.2 10.6 7.2 13.6 7.9 10.2 11.5 12.7 8.6 18.0 12.8 10.1 2.1 10.7 9.1 14.8 13.8 10.5 4.6 18.3 24.7 10.3 13.2 11.7 22.8 7.4 21.3 12.1 9.1 7.9 12.3 13.5 12.0 5.9 15.3 3.6 21.4 22.1 22.5 6.1 6.5 12.9 10.4 1.4 0.7 1.6 0.3 3.8 14.4 2.8 2.5 7.1 2.5 2.9 5.9 3.7 1.6 6.7 11.3 3.0 3.4 6.9 2.4 9.8 3.6 3.1 1.3 2.4 11.6 2.7 20.2 6.2 72.2 21.9 3.2 4.3 1.3 6.1 2.7 4.5 1.0 7.3 3.0 0.0 12.7 6.3 1.9 7.0 4.2 1.6 2.1 0.0 4.6 2.6 13.9 3.8 8.2 2.9 5.4 2.7 2.9 2.8 1.9 1.9 0.0 1.7 1.7 2.3 5.7 5.2 4.0 0.0 3.1 1.4 1.6 0.3 0.5 3.9 0.2 3.6 0.5 7.0 5.3 0.7 1.4 14.4 8.3 0.1 3.8 0.3 0.4 7.3 2.8 18.0 25.8 34.6 20.3 18.0 12.8 14.8 13.8 13.2 21.4 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 335.4;ASC TERT1: 97.7;HSkMC: 83.3;U-138 MG: 91.2;U-87 MG: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" 160000000 Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 197.5 9.0 1.2 13.2 1.6 0.0 136.4 0.8 1.4 74.3 74.4 2.4 36.9 5.6 85.0 123.0 52.3 25.7 115.4 54.0 0.9 0.5 9.4 3.5 38.9 3.9 1.5 1.1 71.0 6.5 0.7 2.2 58.9 2.2 66.8 18.7 36.4 18.6 20.4 68.6 68.2 22.6 57.1 1.8 12.4 20.5 57.0 1.1 1.3 20.6 31.8 9.1 84.1 105.3 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.3 0.2 11.1 0.1 335.4 97.7 18.2 28.7 65.9 5.8 4.6 0.0 0.1 0.0 23.1 50.5 3.1 0.0 0.2 3.3 0.0 0.0 0.0 0.7 0.1 31.7 0.0 0.8 83.3 0.0 29.8 0.2 37.4 0.0 0.1 19.3 0.0 0.0 0.4 8.8 0.0 0.0 2.6 0.0 0.9 0.4 0.1 20.2 5.3 0.0 0.1 0.0 2.0 52.7 91.2 8.7 17.5 3.7 0.0 0.0 0.1 106.8 1.5 16.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 1.2 1.6 0.8 1.4 0.9 0.5 1.5 1.1 2.2 1.1 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801498 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 62.7" "Cell line enhanced" "Detected in some" "AF22: 22.0;HeLa: 8.9;RH-30: 8.9;TIME: 14.0;U-2 OS: 12.0;U-2197: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "non-classical monocyte: 1.7" "Lineage enriched" "Detected in single" 8 "monocytes: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 3.7 2.0 3.4 4.2 17.3 2.4 1.9 1.3 5.6 5.9 4.2 2.6 2.5 2.1 3.0 9.0 7.0 3.4 11.1 5.1 2.5 2.7 1.6 1.4 4.3 1.3 3.3 3.5 12.4 1.5 1.3 2.3 2.6 4.5 3.1 2.2 10.8 2.1 2.7 62.7 2.9 2.1 5.8 1.0 1.5 3.5 2.0 5.4 0.0 1.8 14.8 2.1 5.0 4.7 0.0 0.2 0.0 1.7 0.0 0.1 0.0 0.0 1.0 22.0 0.6 0.4 0.9 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 2.2 3.9 1.8 1.1 1.3 0.0 0.0 0.6 0.0 8.9 0.0 0.5 0.0 0.2 0.0 2.5 0.5 2.2 0.2 0.0 0.1 0.7 0.0 0.0 0.2 2.9 2.0 3.6 8.9 0.0 0.3 0.0 0.0 0.3 1.9 0.0 0.0 0.2 0.0 14.0 0.7 12.0 12.7 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 3.4 17.3 1.3 4.2 2.5 2.7 3.3 3.5 4.5 5.4 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" 340000000 "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavourable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 36.3 17.6 10.2 40.7 14.4 38.5 98.2 8.6 18.6 25.1 21.3 19.2 7.6 6.5 33.4 14.2 15.7 21.8 20.2 53.8 11.5 10.4 25.6 29.5 102.8 85.0 17.5 5.4 28.8 19.4 5.7 10.2 24.2 30.0 23.1 13.0 16.6 16.3 21.9 13.6 19.5 18.3 41.4 21.8 31.6 17.3 9.0 12.9 18.7 26.2 17.6 38.1 22.7 28.9 16.0 36.4 54.1 69.0 28.0 37.1 81.8 27.8 21.4 21.0 17.3 25.2 33.3 0.1 70.7 45.8 39.2 30.4 0.0 4.9 23.4 63.2 62.5 19.2 22.1 50.4 51.2 43.3 6.1 64.9 37.1 0.0 23.8 78.8 105.1 24.9 10.9 72.1 63.8 86.5 31.4 73.0 62.0 0.0 46.5 59.1 26.0 40.7 24.4 37.7 17.8 41.9 0.0 0.1 0.0 56.8 0.4 22.5 0.2 42.9 137.0 44.7 28.4 60.1 46.8 26.5 40.1 25.4 32.7 100.1 49.7 30.8 44.4 30.0 37.1 58.9 27.9 16.0 20.4 29.1 36.4 13.9 14.0 21.3 54.1 28.0 69.0 5.2 15.5 81.8 10.2 14.4 8.6 18.6 11.5 10.4 17.5 5.4 30.0 12.9 MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "liver: 117.0" "Cell line enhanced" "Detected in many" "Hep G2: 41.5;NB-4: 8.4;U-266/70: 11.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 1.1;memory B-cell: 1.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favourable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 3.7 3.5 4.0 0.3 4.8 1.4 1.0 4.9 5.4 0.9 1.4 2.5 1.9 14.4 1.2 3.3 0.8 1.7 1.9 0.5 6.5 1.1 8.8 117.0 1.6 0.7 2.0 2.9 1.7 1.9 3.8 4.8 1.5 4.8 1.5 0.5 1.6 3.4 3.7 2.8 4.0 8.2 1.3 4.2 1.7 0.8 9.9 2.3 0.9 5.0 0.3 1.1 0.8 0.7 1.2 0.9 0.0 0.2 0.0 1.1 0.2 0.1 0.2 0.6 1.0 1.9 4.0 1.9 0.5 0.7 0.3 0.4 1.9 0.6 0.1 1.3 0.6 0.4 0.3 0.8 0.3 0.6 0.3 0.3 0.9 41.5 3.0 0.0 0.8 5.4 1.3 0.3 1.1 0.7 0.3 5.0 0.9 0.3 0.2 8.4 0.1 0.5 0.2 0.2 1.1 2.2 0.3 0.1 1.4 0.0 0.9 0.2 0.7 2.8 0.4 1.0 0.3 0.0 0.1 11.3 1.4 0.2 1.1 1.5 0.7 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.2 4.0 4.8 4.9 5.4 6.5 1.1 2.0 2.9 4.8 2.3 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262507 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "CAB069425: , HPA071227: " "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favourable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 11.3 13.9 18.7 13.0 22.5 12.3 14.9 25.2 25.2 11.3 14.5 18.2 10.4 11.2 13.8 23.6 13.1 10.5 15.7 14.2 14.5 13.6 15.8 19.4 10.8 14.3 14.0 14.4 10.7 16.6 26.5 16.0 12.5 15.5 15.2 17.1 14.4 14.2 15.2 24.6 16.5 13.6 15.2 10.4 15.4 13.1 38.6 13.1 16.6 13.2 9.9 15.7 11.7 10.2 3.9 4.0 3.0 6.4 2.6 5.6 2.3 15.2 13.8 18.7 14.1 22.6 10.8 9.3 12.9 12.4 17.2 17.0 14.2 14.1 16.9 11.1 15.2 18.2 25.2 19.7 22.3 13.5 18.4 22.5 28.6 17.9 14.2 21.9 16.8 13.8 15.0 24.6 25.0 21.8 25.1 14.6 12.0 17.4 15.1 16.7 14.1 13.1 15.2 22.0 11.3 15.2 13.8 18.9 13.8 27.6 14.9 16.9 12.1 13.0 23.2 15.1 13.7 11.5 17.2 14.4 13.4 33.3 10.9 23.7 15.8 0.7 2.9 3.0 5.2 6.4 4.3 3.9 3.0 2.7 4.0 3.4 3.6 3.1 2.0 2.6 3.3 3.1 5.6 2.3 18.7 22.5 25.2 25.2 14.5 13.6 14.0 14.4 15.5 13.1 MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181315-135219173 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 104.9" "Cell line enhanced" "Detected in many" "HL-60: 38.9;MOLT-4: 70.8;NB-4: 36.9;REH: 43.7;THP-1: 61.8;U-937: 33.7" "Cancer enhanced" "Detected in many" "breast cancer: 17.7" "Region enhanced" "Detected in some" "basal ganglia: 4.7" "Group enriched" "Detected in some" 4 "basophil: 5.6;eosinophil: 10.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favourable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favourable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" 0.5 0.7 1.3 9.1 4.7 18.9 13.2 0.3 0.6 1.4 15.4 0.5 0.3 6.5 0.9 1.0 3.7 5.0 1.7 0.6 0.7 0.7 0.4 0.5 1.8 3.3 0.3 0.5 1.0 0.3 0.4 0.3 0.6 0.5 1.6 16.7 0.5 0.8 1.5 1.0 3.5 5.9 0.7 0.4 1.4 0.9 2.0 0.6 104.9 0.4 2.0 4.7 0.7 1.5 0.1 1.7 10.0 0.8 0.0 0.5 0.1 0.3 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 1.8 0.0 0.0 0.1 1.0 0.0 0.1 3.1 0.4 24.8 0.1 0.0 0.0 38.9 19.6 0.0 0.0 0.1 0.0 0.0 20.1 3.7 0.2 2.0 70.8 36.9 0.2 0.3 43.7 1.0 6.0 0.0 0.2 1.9 1.2 0.0 1.9 0.0 1.4 61.8 0.0 0.0 0.3 1.4 0.4 4.7 1.2 12.0 0.0 33.7 0.4 5.6 0.8 10.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 1.7 0.5 0.1 1.3 4.7 0.3 0.6 0.7 0.7 0.3 0.5 0.5 0.6 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281277-36388067 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" 3100000000 "Plasma membrane, Actin filaments" Cytosol "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 115.5 26.1 11.9 43.7 12.9 55.6 59.0 9.3 16.8 67.1 44.6 18.0 26.4 26.9 120.8 39.7 48.3 45.6 66.9 39.2 11.0 8.1 45.0 42.8 74.4 57.7 15.1 9.2 56.4 43.9 19.0 15.4 65.7 17.9 47.6 23.6 32.4 66.2 27.2 36.9 40.3 49.8 46.7 13.5 91.5 37.1 25.8 11.9 76.0 42.5 38.4 65.0 56.0 53.7 6.9 8.2 28.5 11.5 4.2 16.6 19.3 60.6 28.2 9.0 7.6 16.8 21.1 45.7 40.7 52.7 58.2 43.7 30.4 17.5 15.7 24.2 68.1 42.1 13.1 79.7 60.0 35.4 12.4 30.3 30.3 25.9 51.5 34.4 48.6 24.9 24.6 78.6 66.8 47.9 6.6 21.3 46.5 16.1 12.2 20.3 5.3 17.4 23.3 27.9 14.6 32.9 59.1 13.5 5.5 57.2 22.5 26.2 16.8 17.8 137.0 129.1 39.2 24.7 73.5 14.1 11.1 13.3 48.9 17.4 37.4 26.8 10.4 28.5 16.6 9.6 14.7 6.9 12.0 13.2 8.2 6.4 9.6 10.1 19.7 4.2 11.5 3.8 12.6 19.3 11.9 12.9 9.3 16.8 11.0 8.1 15.1 9.2 17.9 11.9 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213008 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;ovary: 29.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 23.4;THP-1: 20.5;U-138 MG: 15.7;WM-115: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 1.9;neutrophil: 3.8" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 6.2 8.5 17.8 2.4 14.2 1.5 7.1 14.7 25.2 2.8 2.1 9.7 2.6 1.2 4.1 5.8 3.8 3.6 8.6 3.7 14.2 7.5 1.4 2.3 3.8 1.6 7.8 13.0 29.6 1.4 2.2 9.3 4.3 7.1 4.5 2.0 12.3 2.2 5.1 2.6 4.1 1.3 4.6 10.6 12.7 1.6 5.0 8.3 0.0 1.7 0.0 1.4 3.9 2.3 0.3 0.1 3.8 0.2 0.1 0.0 0.0 1.8 4.3 0.3 0.1 4.5 9.3 0.1 13.1 10.3 5.4 2.8 1.2 0.3 0.1 1.0 10.5 1.4 3.8 2.0 9.6 0.0 0.0 0.0 1.8 0.1 3.5 0.0 0.1 3.4 0.0 23.4 5.9 8.0 0.0 0.0 13.2 0.1 0.0 5.9 1.5 1.2 0.6 1.1 0.0 0.9 0.0 0.3 0.0 0.9 0.1 1.8 0.0 20.5 6.9 15.7 4.4 6.7 9.0 0.7 0.0 0.4 4.7 0.2 19.4 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.8 0.1 0.2 0.1 0.0 0.0 17.8 14.2 14.7 20.5 14.2 7.5 7.8 13.0 7.1 8.3 NBPF10 AG1 ENSG00000271425 "NBPF member 10" 1 146064699-146144804 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA038748: , HPA042595: , HPA043105: , HPA043692: , HPA044023: , HPA046971: , HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" 1.5 0.0 0.9 3.3 2.3 0.0 3.0 0.9 0.0 1.6 1.9 1.0 1.3 0.5 0.0 0.4 1.2 1.3 0.6 3.2 1.1 1.5 0.7 1.1 1.1 0.3 1.3 0.0 4.2 0.0 1.5 2.0 0.1 1.2 0.7 0.6 0.2 1.3 2.4 3.7 1.5 0.4 0.4 0.2 5.4 1.4 3.2 2.3 11.3 13.5 2.8 3.1 4.2 3.1 3.2 1.4 2.5 2.5 0.6 6.1 2.7 3.8 4.2 6.4 2.8 2.4 5.4 3.8 0.7 4.5 2.5 1.7 12.3 4.0 8.3 8.5 3.8 1.7 7.7 6.7 6.7 1.0 2.2 1.5 4.4 1.3 2.0 3.3 2.4 3.7 0.3 0.4 4.7 4.7 1.6 3.8 3.1 11.4 3.1 2.7 2.9 3.8 4.7 1.9 3.0 2.8 2.7 2.4 0.8 1.5 1.8 0.4 1.1 0.2 1.1 0.2 0.3 0.7 1.3 0.4 0.3 3.7 0.4 1.2 2.4 0.3 0.2 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501902-47656877 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavourable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 20.1 8.9 6.6 34.0 7.4 11.1 15.7 11.9 9.9 12.3 10.1 8.1 9.0 6.7 15.5 8.8 16.7 12.0 8.6 11.5 6.7 4.8 9.1 9.3 17.4 25.8 7.9 4.7 13.3 10.7 13.5 13.5 54.7 7.9 9.7 9.0 10.8 13.5 10.0 32.5 15.0 17.1 11.3 9.5 30.8 11.4 9.2 7.2 17.6 13.5 10.5 33.3 15.1 17.7 13.0 6.7 6.0 7.3 2.7 4.0 3.5 5.7 18.8 5.3 7.2 12.5 14.7 37.3 5.6 8.4 9.6 5.1 9.0 6.4 20.1 3.7 9.6 14.2 4.1 6.9 7.3 10.6 2.2 2.7 5.3 12.5 7.4 2.1 15.0 6.7 19.8 9.1 10.6 6.8 6.2 4.7 5.3 62.6 3.2 3.7 1.8 7.2 6.0 3.7 8.6 5.3 13.6 1.0 1.9 14.1 17.6 6.0 8.1 5.5 11.8 5.7 5.0 6.9 2.4 12.9 11.8 20.7 6.6 2.2 3.8 3.4 5.2 4.0 3.5 7.3 3.2 13.0 3.2 3.1 6.7 10.0 3.7 4.0 6.0 2.7 7.0 5.5 4.0 3.5 6.6 7.4 11.9 9.9 6.7 4.8 7.9 4.7 7.9 7.2 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030714 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 100.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 30.2;granulocytes: 100.1;monocytes: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: , HPA065208: " "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favourable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favourable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 18.5 6.9 5.5 9.5 10.0 17.4 10.0 5.5 11.3 10.8 22.5 13.6 5.9 27.0 9.9 9.4 17.0 6.3 9.0 16.6 5.7 20.8 40.9 11.6 11.6 8.7 7.1 11.0 9.1 9.3 9.6 28.4 13.5 14.7 12.4 9.9 12.6 8.5 15.5 6.8 36.4 11.2 9.7 23.8 8.9 6.4 8.1 26.8 13.2 13.9 16.3 13.0 6.4 7.3 30.2 100.1 40.4 13.4 10.9 53.9 31.3 13.3 15.6 16.0 41.4 37.6 39.1 28.8 46.7 28.5 27.9 20.4 23.2 35.4 34.7 47.1 32.0 16.3 31.7 31.7 25.0 16.8 23.9 18.3 58.5 29.1 60.8 53.4 36.5 31.8 24.2 40.7 41.8 26.0 21.4 38.7 14.0 29.5 22.8 9.4 7.8 17.5 22.7 21.2 34.1 26.7 15.7 10.6 29.1 33.3 28.8 24.0 29.9 38.5 17.6 21.2 18.6 19.4 15.9 17.0 35.2 22.0 51.2 9.3 69.1 40.4 70.7 10.0 26.8 10.9 7.3 9.4 9.5 30.2 6.6 10.2 8.6 100.1 13.4 30.4 9.3 10.8 53.9 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB072830: , HPA043246: , HPA050288: , HPA051168: " "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favourable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 19.6 21.2 25.4 24.0 30.8 27.0 25.0 41.8 31.5 24.0 30.6 19.6 18.6 33.2 29.0 19.5 25.0 20.5 21.9 17.8 22.4 17.8 25.6 33.8 20.1 19.5 25.1 19.1 25.9 24.3 39.9 39.8 19.8 21.6 20.8 29.7 17.1 20.9 29.1 43.0 23.8 36.9 29.7 26.4 23.7 29.8 22.1 26.4 38.8 25.3 15.7 23.8 29.6 27.0 43.4 29.9 78.2 24.8 30.4 35.5 19.7 23.8 39.9 28.5 23.7 23.5 17.9 14.2 17.6 19.9 19.4 17.6 21.3 10.9 25.1 12.4 30.7 18.3 35.0 21.3 28.8 33.4 25.9 25.0 34.5 25.0 23.0 15.6 29.8 18.3 22.4 30.0 35.2 26.9 21.8 10.4 19.0 15.5 27.5 10.1 14.1 10.9 27.5 28.9 11.7 20.1 27.1 9.7 16.2 29.1 12.7 13.8 12.2 17.9 23.4 20.0 11.8 14.6 24.2 7.2 8.3 14.7 19.0 18.6 17.1 78.2 24.8 52.2 31.3 19.5 25.9 40.7 35.5 34.1 17.5 43.4 34.7 34.8 48.5 30.4 24.0 29.9 31.7 19.7 25.4 30.8 41.8 31.5 22.4 17.8 25.1 19.1 21.6 26.4 NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567589 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm Nucleoplasm "HPA001928: AB_1079454" "unprognostic (9.51e-3)" "unprognostic (7.37e-3)" "unprognostic (4.66e-2)" "unprognostic (2.55e-3)" "unprognostic (2.14e-1)" "unprognostic (7.37e-2)" "unprognostic (3.19e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-3)" "unprognostic (6.42e-3)" "unprognostic (1.96e-1)" "unprognostic (9.86e-2)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.56e-2)" "unprognostic (8.90e-2)" 24.0 22.0 21.3 21.3 19.0 16.8 18.3 33.8 33.5 24.5 17.2 24.3 17.7 16.4 21.3 19.0 15.7 16.3 21.5 18.2 22.0 14.8 16.0 11.2 23.4 11.9 19.0 15.6 28.6 30.0 13.8 39.5 13.2 28.3 21.3 7.6 32.7 29.2 24.5 62.4 22.8 22.2 17.4 12.2 17.4 24.0 10.8 22.0 9.3 16.7 25.0 7.6 16.3 14.7 0.6 1.7 8.1 4.0 0.2 1.9 0.4 19.4 36.7 10.5 10.0 6.1 8.3 31.4 20.2 10.1 11.8 5.3 19.5 14.4 19.8 15.0 16.4 18.5 4.1 21.5 4.8 20.8 8.1 15.9 34.6 11.8 12.3 11.9 20.2 13.3 8.1 14.7 8.8 11.2 20.4 5.9 10.5 16.8 42.9 13.8 14.6 35.8 13.9 17.5 10.0 5.6 22.8 27.7 20.2 24.8 21.0 12.7 17.1 15.1 53.9 27.5 47.6 27.1 42.9 11.3 11.4 12.1 15.6 8.9 25.7 8.1 0.7 1.6 1.9 0.4 0.5 0.6 0.5 1.5 0.3 0.4 0.6 0.5 1.6 0.2 4.0 1.7 0.0 0.4 21.3 19.0 33.8 28.4 22.0 14.8 19.0 15.6 28.3 22.0 NEB "NEB177D, NEM2" ENSG00000183091 Nebulin P20929 2 151485336-151734487 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 505.8" "Cell line enhanced" "Detected in some" "Karpas-707: 6.7;RH-30: 26.6;U-266/70: 10.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 7.4;olfactory region: 4.9" "Region enriched" "Detected in some" 7 "cerebellum: 25.3" HPA016601 Enhanced "HPA016601: AB_1854361" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (2.13e-2)" "unprognostic (2.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-3)" "unprognostic (2.54e-2)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-13)" "unprognostic (6.80e-2)" "unprognostic (2.22e-2)" "unprognostic (4.07e-3)" "unprognostic (4.06e-2)" 9.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 5.2 4.0 0.0 0.8 1.5 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.0 3.8 0.0 505.8 0.3 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 3.0 65.9 2.6 0.1 0.0 1.3 0.5 1.7 0.6 0.8 0.9 0.3 0.3 0.3 0.6 0.5 0.1 0.1 1.7 0.3 0.0 0.0 0.0 4.6 0.5 1.2 0.9 0.1 0.9 0.1 0.0 0.0 0.6 0.7 0.4 0.6 1.5 0.0 0.8 1.1 4.0 0.2 0.0 0.0 0.6 0.9 6.7 0.4 0.5 0.4 0.7 1.1 0.8 1.1 26.6 0.1 0.0 0.9 1.5 0.2 0.2 0.3 0.1 0.7 0.8 0.6 0.7 0.9 0.1 0.9 10.0 1.4 0.3 0.1 0.6 1.1 1.2 0.6 1.7 0.9 0.0 0.9 1.2 0.8 0.5 0.0 1.3 0.3 0.4 1.1 0.8 0.0 0.5 0.4 0.3 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" Q96PU5 18 58044367-58401540 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 50.1;SK-MEL-30: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favourable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 5.9 6.8 9.1 5.4 38.8 13.2 15.8 21.4 24.7 5.0 22.6 3.2 18.2 11.1 3.6 6.1 7.0 6.0 7.6 12.7 9.8 7.1 29.9 10.1 26.9 2.5 7.2 14.9 3.0 33.2 9.2 16.5 13.0 4.1 30.6 25.2 12.2 16.5 23.2 38.3 5.9 26.8 8.2 3.2 3.1 26.0 4.6 8.8 0.8 9.1 5.5 5.1 14.9 9.3 1.4 0.4 4.7 0.7 0.9 8.1 0.5 18.4 6.6 3.9 5.8 1.4 0.5 13.6 5.2 23.7 13.4 20.5 7.7 10.0 3.9 16.1 2.0 13.4 5.2 23.1 27.7 9.2 4.6 2.8 4.1 50.1 0.7 0.1 1.7 3.5 15.1 18.1 22.0 1.0 4.8 1.7 5.5 4.5 0.2 0.2 3.4 10.2 3.8 5.3 4.5 13.3 24.1 4.9 1.3 4.3 1.3 39.1 7.9 1.6 7.9 36.2 10.9 2.0 22.3 2.3 3.9 2.4 7.4 2.8 2.9 4.7 0.6 1.7 0.4 0.7 1.0 1.4 1.3 0.3 0.3 0.6 0.8 0.6 0.3 0.9 0.1 0.4 8.1 0.5 9.1 38.8 21.4 24.7 9.8 7.1 7.2 14.9 4.1 8.8 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 2.3;granulocytes: 6.5;T-cells: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria Mitochondria "HPA045502: " "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 12.9 15.9 22.6 13.3 25.9 5.5 18.5 30.2 26.0 17.6 13.6 19.8 12.2 11.0 16.9 17.0 10.5 15.2 13.1 17.3 21.6 19.6 20.0 15.1 12.7 11.5 19.4 25.6 22.9 16.5 34.1 19.0 19.4 20.9 16.1 14.7 12.1 14.4 20.5 14.8 12.0 12.1 14.5 21.4 11.9 13.0 15.4 21.5 11.6 31.1 7.6 12.4 15.3 19.5 2.3 0.7 6.5 0.4 0.9 8.4 1.0 9.7 12.7 15.5 8.3 13.2 17.2 7.8 8.4 15.3 12.5 14.2 11.4 6.6 9.4 2.4 15.8 17.1 14.0 11.9 21.3 4.5 8.8 8.3 12.0 5.8 9.4 14.8 6.9 13.6 7.6 13.3 16.3 6.0 11.9 9.4 11.9 7.7 12.3 5.4 4.5 4.2 9.7 23.7 7.5 9.5 14.0 6.4 9.6 15.7 5.3 8.7 16.0 9.5 8.8 10.0 14.0 11.8 3.2 8.5 4.1 10.4 8.2 6.3 10.4 6.5 0.4 0.9 2.3 0.2 1.6 2.3 4.4 3.9 0.5 2.1 3.3 3.2 1.0 0.9 0.4 0.7 8.4 1.0 22.6 25.9 30.2 23.5 21.6 19.6 19.4 25.6 20.9 21.5 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: " "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favourable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 30.9 24.4 25.4 19.3 34.7 15.0 24.6 36.4 29.7 31.7 28.3 25.8 22.2 28.1 27.7 30.9 82.5 27.0 28.9 32.3 28.0 16.9 44.8 49.3 29.0 19.7 49.0 18.7 53.1 16.3 21.7 52.5 29.4 33.5 39.0 25.4 21.7 34.7 28.1 25.9 48.1 29.2 42.1 42.7 26.8 45.9 21.9 41.6 21.1 49.5 35.8 25.5 43.7 47.1 23.5 41.1 42.4 35.6 25.8 43.2 22.6 10.9 12.7 11.5 12.4 39.0 42.1 13.2 18.7 26.1 17.1 19.4 16.8 21.0 10.8 20.4 21.2 20.4 13.5 28.6 24.0 8.4 8.2 13.9 22.3 32.6 49.9 8.2 13.2 28.9 67.3 24.3 36.2 16.9 14.5 21.3 23.5 10.9 8.4 21.8 12.6 11.9 6.9 10.1 10.9 26.1 41.4 15.1 9.8 42.5 13.7 44.4 10.6 22.3 25.5 17.8 11.8 19.7 11.5 15.0 9.0 9.1 17.8 9.2 34.0 42.4 35.6 21.4 23.0 34.1 26.6 23.5 26.9 23.6 41.1 19.9 43.2 28.2 39.9 25.8 31.9 15.5 25.0 22.6 25.4 34.7 36.4 29.7 28.0 16.9 49.0 18.7 33.5 41.6 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831121 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Centrosome "Nucleoplasm, Nucleoli" "HPA005939: , HPA070691: " "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 13.0 6.1 15.1 24.9 10.3 34.8 9.7 12.6 14.0 8.0 9.2 7.6 4.5 5.0 11.8 6.1 11.8 8.2 7.6 16.4 11.7 4.9 6.7 5.2 10.7 30.2 7.6 10.0 11.0 5.4 9.1 12.3 20.2 7.1 6.5 7.7 6.2 8.2 5.1 16.9 10.9 8.3 12.0 7.1 18.2 9.3 4.6 9.0 16.4 7.8 5.1 25.8 11.7 10.3 6.8 6.3 18.4 2.3 1.5 6.0 1.3 12.2 8.7 18.1 15.4 7.0 11.2 7.6 10.5 9.1 8.9 7.5 5.6 6.5 28.8 7.2 14.1 12.9 14.5 6.6 18.7 13.9 4.5 10.6 5.3 5.3 4.1 18.4 30.6 7.7 5.3 15.5 6.4 14.1 2.6 11.8 13.4 13.4 13.9 7.4 2.5 9.6 15.8 33.5 2.0 8.0 13.9 8.4 9.5 13.2 4.0 11.3 7.5 16.4 20.5 22.6 31.4 8.6 11.6 9.5 4.8 19.9 5.9 15.0 12.2 12.6 2.3 18.4 3.3 1.7 3.5 6.8 2.2 6.0 1.5 5.5 4.4 3.8 8.3 1.5 1.5 6.3 1.9 1.3 15.1 10.3 12.6 14.0 11.7 4.9 7.6 10.0 7.1 9.0 NLRP3 "AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, MWS, NALP3, PYPAF1" ENSG00000162711 "NLR family pyrin domain containing 3" Q96P20 1 247416156-247449108 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" Activator "Amyloidosis, Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 40.3;bone marrow: 38.2" "Cell line enhanced" "Detected in some" "NB-4: 7.1;THP-1: 40.7;U-937: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 40.3" "Group enriched" "Detected in many" 20 "dendritic cells: 13.4;granulocytes: 40.3;monocytes: 12.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012878 Uncertain "Intracellular and membrane" "HPA012878: AB_1846752" "unprognostic (3.56e-2)" "unprognostic (1.33e-1)" "unprognostic (6.23e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (7.86e-2)" "unprognostic (4.46e-2)" "unprognostic (3.84e-1)" "unprognostic (7.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-2)" "unprognostic (4.88e-3)" "unprognostic (2.17e-4)" "unprognostic (1.10e-1)" "unprognostic (6.10e-2)" 7.4 1.4 2.8 8.3 3.3 38.2 3.2 0.7 3.7 1.8 1.5 6.9 1.5 0.8 4.5 0.9 2.4 3.0 8.9 2.0 3.0 3.1 1.3 1.8 8.2 8.9 3.3 0.8 1.3 1.4 1.1 1.2 3.0 5.2 1.0 1.7 2.4 1.5 0.7 0.9 0.8 2.5 4.1 4.9 8.5 1.6 0.6 3.3 1.0 1.0 3.2 2.8 3.3 0.9 0.0 13.4 40.3 12.5 0.0 1.1 3.9 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 1.5 0.2 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.1 0.0 0.2 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 40.7 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.0 3.9 10.1 1.2 40.3 12.5 0.1 0.2 7.7 0.6 0.0 1.1 0.4 13.4 0.0 0.4 0.2 3.0 0.0 3.6 0.6 0.0 3.9 2.8 3.3 0.7 3.7 3.0 3.1 3.3 0.8 5.2 3.3 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71283192-71301168 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" 150000 Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavourable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 37.2 55.9 30.2 37.7 30.8 51.2 37.2 54.8 38.6 45.4 33.4 36.0 38.4 29.9 52.4 40.5 41.0 40.5 37.2 30.5 27.5 29.0 40.1 43.3 37.3 45.7 28.8 31.7 69.2 61.0 39.4 48.2 42.4 27.5 40.8 37.5 42.5 39.8 41.4 37.2 38.4 35.2 40.5 38.3 45.9 40.3 34.4 29.0 98.4 51.0 39.1 57.4 43.6 36.8 44.1 47.3 35.3 51.8 45.4 51.8 58.9 58.5 64.8 89.7 49.2 36.6 37.8 49.1 48.0 44.7 65.0 57.4 51.4 43.5 66.6 53.5 44.2 43.8 133.8 41.7 71.6 50.7 89.4 54.6 68.0 51.1 31.0 76.6 48.0 40.0 29.8 65.7 44.1 53.3 69.6 69.9 59.9 52.0 99.0 69.8 111.6 52.6 89.1 94.0 57.1 49.8 51.8 62.3 77.3 62.2 40.6 55.1 38.2 49.6 48.9 42.1 63.2 58.8 55.5 40.3 76.3 75.8 31.4 89.1 60.1 35.3 44.8 34.9 45.8 47.6 51.8 43.7 46.6 44.9 47.3 44.1 50.8 50.2 20.8 45.4 51.8 41.2 50.1 58.9 30.2 30.8 54.8 38.6 27.5 29.0 28.8 31.7 27.5 29.0 NOTCH1 TAN1 ENSG00000148400 "Notch 1" P46531 9 136494433-136545786 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 24.5;HMC-1: 21.3;hTCEpi: 23.6;MOLT-4: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.8" "Group enriched" "Detected in many" 4 "granulocytes: 8.8;NK-cells: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm 8100000 Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: " "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavourable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 20.0 4.0 10.0 14.5 10.4 14.6 12.8 3.8 18.8 12.8 14.2 19.9 8.2 9.8 11.2 5.1 13.3 9.6 13.1 9.6 10.7 5.8 9.4 7.2 17.4 13.7 11.6 7.5 9.2 17.8 3.7 5.6 8.5 9.3 12.1 5.7 10.4 14.2 11.8 8.2 32.3 10.8 7.7 6.6 20.7 8.6 4.1 9.9 34.8 9.4 10.2 10.9 12.3 22.2 0.6 1.1 8.8 1.0 2.7 1.3 0.9 4.4 7.3 6.1 3.0 0.2 0.5 7.6 2.2 0.6 1.3 0.4 1.0 0.5 5.9 4.6 1.7 24.5 2.0 10.0 0.2 13.5 1.1 3.3 3.0 0.4 3.4 3.5 21.3 0.3 23.6 1.7 3.7 7.8 1.4 1.1 0.8 7.9 37.4 5.7 5.1 3.4 7.7 4.9 11.0 0.9 3.7 0.0 0.4 3.2 3.4 1.4 2.1 5.6 11.5 3.2 4.7 3.1 2.4 1.2 1.0 2.4 2.2 2.5 16.5 0.7 1.0 2.8 1.3 0.4 0.8 0.4 0.6 1.0 0.6 0.6 0.4 1.1 8.8 2.7 0.4 1.1 0.4 0.9 10.0 10.4 3.8 11.7 10.7 5.8 11.6 7.5 9.3 9.9 NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411137 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced Nucleoplasm,Nucleoli 810000 Nucleoli Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavourable (7.48e-4)" "prognostic unfavourable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" 56.8 44.7 29.9 61.1 33.6 76.0 67.0 37.7 34.6 113.5 57.8 24.8 39.3 36.7 78.2 50.5 81.6 65.0 44.0 48.5 28.8 31.6 64.9 78.8 59.5 128.1 36.1 27.9 177.4 102.0 27.1 57.9 65.2 36.1 87.2 49.3 29.5 47.3 48.2 67.9 42.7 52.8 92.4 43.2 85.9 54.0 56.7 31.3 111.3 112.6 66.5 82.1 116.8 65.7 85.3 54.1 12.3 29.1 59.0 126.6 91.4 118.4 80.2 97.5 138.1 59.6 108.9 145.4 107.8 98.5 146.1 131.6 191.5 83.7 317.2 85.7 62.3 69.5 135.3 245.1 190.4 98.7 107.3 111.9 78.7 141.0 88.4 225.3 92.8 96.0 86.4 99.1 195.6 109.0 136.0 73.0 106.0 147.1 147.0 160.3 122.0 98.6 132.0 107.6 162.6 124.6 83.6 76.9 61.8 64.4 105.4 195.1 129.3 100.0 68.0 48.9 107.8 56.2 181.5 58.5 106.3 190.8 73.9 183.5 97.4 12.3 26.9 8.4 45.7 29.1 84.6 85.3 85.1 66.2 54.1 62.8 126.6 99.0 4.0 59.0 23.1 48.7 73.2 91.4 29.9 33.6 37.7 34.6 28.8 31.6 36.1 27.9 36.1 31.3 NR1H2 "LXR-b, NER, NER-I, RIP15, UNR" ENSG00000131408 "Nuclear receptor subfamily 1 group H member 2" P55055 19 50329653-50382982 "Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005446, HPA056838, HPA070212" Uncertain Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA005446: , HPA056838: , HPA070212: " "unprognostic (1.31e-1)" "unprognostic (5.35e-2)" "prognostic unfavourable (9.86e-4)" "unprognostic (1.34e-3)" "unprognostic (1.68e-1)" "unprognostic (5.24e-3)" "unprognostic (2.26e-2)" "unprognostic (9.69e-2)" "unprognostic (6.45e-2)" "unprognostic (5.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.88e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (5.12e-2)" "unprognostic (1.69e-3)" 30.1 27.5 24.5 24.7 27.5 98.0 24.4 20.6 33.5 25.1 30.9 23.1 25.2 30.9 31.2 23.1 27.9 26.9 28.7 36.8 23.8 19.4 27.1 31.4 28.3 23.3 31.7 25.9 26.5 37.6 22.0 18.6 30.5 28.1 27.9 10.5 23.2 33.8 33.8 76.2 25.3 30.3 29.9 22.9 29.9 26.7 21.2 29.1 20.4 27.1 24.4 21.7 33.2 27.6 34.1 34.2 63.0 37.7 22.3 28.6 32.5 16.0 42.2 4.1 10.3 12.1 12.8 13.2 22.2 18.9 13.2 15.1 8.7 15.6 10.3 19.9 13.3 15.0 2.6 12.1 3.2 25.7 22.7 9.9 14.2 9.0 23.3 16.3 27.1 13.4 16.6 13.5 9.2 12.0 16.1 21.5 7.4 17.8 11.6 13.4 8.3 36.3 7.0 10.7 17.9 11.3 18.0 4.6 16.1 14.4 17.9 13.9 12.3 13.6 15.1 17.7 14.4 18.0 19.7 26.9 22.2 7.5 35.3 10.8 17.7 39.1 35.9 63.0 27.7 35.0 27.0 34.1 27.4 25.9 34.2 34.1 28.6 24.9 55.4 22.3 37.7 29.5 24.4 32.5 24.5 27.5 20.6 33.5 23.8 19.4 31.7 25.9 28.1 29.1 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324432-156342348 "Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 102.1" "Cell line enhanced" "Detected in many" "HeLa: 14.2;HMC-1: 10.5;U-266/70: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 15.0 58.5 3.1 10.2 5.7 49.1 7.5 15.2 14.4 9.1 4.2 7.3 11.0 1.4 6.4 7.5 5.7 13.6 21.3 15.8 5.2 2.6 5.9 7.6 12.5 2.8 4.8 4.2 60.0 4.2 8.7 23.7 2.3 5.1 11.7 8.5 5.3 18.0 102.1 6.1 5.3 6.0 8.4 5.9 2.1 8.3 3.8 3.7 2.1 6.8 8.0 5.3 17.8 7.5 0.7 2.8 10.1 2.3 0.0 1.6 0.6 0.8 1.2 0.5 1.7 3.1 0.6 0.8 1.0 5.2 0.4 1.3 0.0 3.6 0.0 1.2 0.4 1.5 2.5 0.7 0.4 1.2 1.3 0.9 14.2 0.0 0.6 0.8 10.5 0.6 1.1 0.4 0.4 0.3 1.4 1.0 1.0 1.7 0.0 0.8 2.2 0.9 0.2 0.7 3.0 0.6 0.8 2.6 0.1 2.5 3.9 6.9 0.2 0.9 0.7 2.8 0.8 0.7 0.4 14.2 1.5 0.0 5.2 0.9 6.6 3.0 2.3 3.4 1.6 0.5 0.9 0.7 0.5 0.8 2.8 0.5 0.9 0.4 10.1 0.0 0.9 0.0 0.5 0.6 3.1 5.7 15.2 14.4 5.2 2.6 4.8 4.2 5.1 3.7 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716894 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830" Uncertain 4800000 "CAB010157: AB_632073, HPA049830: " "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavourable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavourable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavourable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 18.0 9.7 13.1 16.5 14.4 33.5 12.4 9.7 16.6 10.0 18.4 15.8 3.8 14.4 9.8 6.2 19.7 8.7 11.8 7.1 11.7 13.8 24.0 23.9 13.4 18.7 15.3 9.6 10.3 14.2 8.3 7.6 27.4 19.0 9.2 18.5 8.4 12.4 5.2 7.9 16.1 23.4 9.6 20.9 19.5 14.4 9.8 9.7 45.0 11.1 14.0 19.6 13.2 10.5 11.0 9.9 23.7 15.0 12.1 11.1 10.1 24.4 6.6 17.9 6.7 7.4 15.9 12.8 11.7 13.1 21.9 24.7 13.3 9.1 18.6 15.6 15.7 7.0 23.9 18.9 31.5 25.3 9.3 12.6 10.1 15.8 14.7 31.2 19.6 14.3 15.4 25.1 18.4 27.8 20.0 21.4 19.3 65.4 21.5 12.1 30.3 4.8 16.5 31.8 11.5 19.4 13.2 10.8 16.3 12.0 9.9 28.1 8.7 25.4 21.2 12.0 22.9 22.3 23.9 37.9 26.1 21.8 24.0 17.1 43.0 23.7 10.0 9.6 9.8 15.0 8.9 11.0 8.0 9.7 9.9 8.8 8.7 11.1 2.7 12.1 12.7 7.7 10.4 10.1 13.1 14.4 9.7 16.6 11.7 13.8 15.3 9.6 19.0 9.7 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300215 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA048431: , HPA070333: , HPA073705: " "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 11.8 13.2 11.9 25.4 15.7 23.9 14.0 28.9 16.7 15.6 14.2 18.5 17.0 10.6 19.0 13.9 17.8 13.6 15.8 11.7 12.8 11.5 14.4 10.5 12.3 19.4 12.9 11.7 16.6 27.1 24.6 19.3 16.0 13.4 14.2 14.3 13.8 13.5 18.7 20.6 16.1 14.5 15.6 13.2 16.1 13.1 28.1 16.1 27.3 20.1 10.6 22.7 13.4 20.2 10.2 8.9 18.7 10.8 10.9 7.8 2.9 9.7 12.6 13.1 11.3 6.4 8.3 0.4 8.8 8.9 12.4 11.6 2.8 8.2 20.1 10.0 12.1 8.4 20.8 19.6 15.1 34.0 12.6 8.9 14.2 0.1 10.7 19.2 10.6 7.8 11.9 14.7 13.8 18.0 12.1 7.1 12.5 20.4 13.3 6.2 14.2 11.1 14.8 1.7 6.2 8.0 11.8 15.9 11.0 22.9 10.0 6.9 10.0 16.0 13.3 8.7 12.6 5.5 10.9 8.3 7.2 14.4 5.0 9.4 9.3 10.7 9.1 9.4 7.5 6.1 6.3 8.5 6.3 5.0 6.7 10.2 7.8 6.3 18.7 10.9 10.8 8.9 5.7 2.9 11.9 15.7 28.9 16.7 12.8 11.5 12.9 11.7 13.4 16.1 NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favourable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" 29.7 33.5 23.6 20.6 28.1 26.8 33.1 38.4 31.8 51.9 37.7 55.6 40.1 25.5 58.3 30.9 34.1 37.8 31.2 21.2 21.6 19.4 23.0 13.1 28.3 23.3 37.6 24.8 51.4 30.0 70.7 29.5 26.0 28.3 50.3 24.2 41.2 35.3 40.1 43.7 41.9 30.2 45.3 29.5 23.0 31.2 25.9 39.5 39.4 32.6 22.5 31.8 50.5 37.2 10.3 12.9 4.9 5.7 7.0 9.7 6.6 18.5 23.6 29.6 19.9 26.3 27.5 15.1 25.1 29.1 26.2 22.9 24.5 34.4 25.3 22.0 30.7 39.9 27.0 25.4 24.0 26.0 12.7 31.0 37.1 18.6 21.2 23.4 22.6 29.0 16.8 25.6 25.9 22.1 18.2 30.6 17.8 35.8 30.2 13.1 18.4 17.0 37.1 51.6 19.5 19.6 29.1 35.8 50.8 40.0 37.1 37.3 49.9 13.7 30.4 27.8 21.7 39.2 16.6 19.8 19.6 35.6 18.6 11.1 15.8 4.9 5.6 2.5 9.7 3.5 7.4 5.2 6.0 7.5 4.9 10.3 7.5 5.2 4.6 7.0 5.7 12.9 7.2 6.6 23.6 28.1 38.4 31.8 21.6 19.4 37.6 24.8 28.3 39.5 NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125561-131234670 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 131.5" "Cell line enhanced" "Detected in all" "K-562: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 43.7;neutrophil: 131.5" "Group enriched" "Detected in many" 5 "granulocytes: 131.5;monocytes: 43.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048789 Approved "Nucleoplasm,Vesicles,Focal adhesion sites" 100000 Nucleoplasm "Vesicles, Focal adhesion sites" "HPA048789: " "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favourable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" 16.9 10.3 11.5 13.8 13.9 29.4 12.9 13.0 14.4 10.2 11.4 19.8 10.4 9.0 15.0 13.7 16.1 12.1 10.2 9.7 9.5 8.1 19.0 15.1 11.7 13.3 13.2 8.8 14.2 17.0 16.7 16.9 13.0 11.3 11.1 10.8 15.3 13.0 11.1 15.5 17.5 11.7 11.1 14.3 35.8 12.3 63.7 13.3 27.4 11.8 7.6 16.8 10.7 11.2 1.2 16.8 131.5 43.7 1.2 0.8 17.9 6.7 9.6 8.2 4.9 6.6 6.4 8.6 6.0 6.2 7.8 6.3 7.8 4.9 10.9 4.8 8.2 15.4 11.0 7.8 7.6 7.9 5.4 6.8 13.7 15.2 5.8 10.6 7.3 7.0 7.2 10.0 8.1 8.0 71.4 6.3 8.0 12.5 13.9 16.0 8.9 8.5 4.8 10.3 10.9 9.0 6.2 7.0 7.2 10.0 9.2 5.2 12.1 26.4 6.8 13.8 7.8 9.0 9.6 5.5 10.7 10.5 6.7 6.4 8.3 3.5 43.7 17.3 0.7 18.4 0.8 1.2 0.7 0.6 16.8 1.1 0.7 0.7 131.5 1.2 15.0 1.5 0.4 17.9 11.5 13.9 13.0 14.4 9.5 8.1 13.2 8.8 11.3 13.3 NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730105-56850286 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavourable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" 14.2 12.2 14.8 15.6 29.7 33.7 12.6 16.8 29.1 12.7 12.4 14.4 4.4 7.2 15.0 9.8 16.8 12.0 8.6 11.5 26.1 11.2 9.9 6.9 12.6 19.1 13.1 16.7 13.4 9.8 16.5 9.6 14.1 23.8 13.9 14.5 23.0 10.4 10.2 15.5 16.3 11.2 14.5 20.7 17.8 11.1 29.3 13.9 28.0 27.4 10.4 22.5 11.5 13.2 12.0 16.9 54.1 21.3 15.1 14.6 11.9 19.1 23.8 21.6 23.5 8.3 9.1 23.9 16.8 13.7 41.8 28.7 32.7 19.2 30.1 16.9 15.8 34.4 40.9 23.9 41.3 9.2 22.3 20.1 17.2 26.7 10.2 26.6 24.1 9.1 10.5 28.3 17.9 24.0 24.3 6.0 20.6 13.7 35.7 22.9 27.4 26.7 43.4 36.4 30.4 16.2 12.8 19.1 12.6 43.8 15.4 13.8 11.7 16.6 16.0 19.9 22.3 16.6 19.0 10.4 14.2 50.2 14.0 25.2 19.4 5.1 14.3 54.1 11.9 21.3 14.6 12.0 9.1 12.9 16.9 11.6 9.5 13.2 3.6 15.1 20.9 8.8 11.0 11.9 14.8 29.7 16.8 29.1 26.1 11.2 13.1 16.7 23.8 13.9 NUP98 NUP96 ENSG00000110713 "Nucleoporin 98" P52948 11 3671083-3797792 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074810 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA074810: " "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.41e-2)" "unprognostic (2.13e-1)" "unprognostic (7.71e-3)" "unprognostic (3.40e-1)" "unprognostic (4.08e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (7.76e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (5.09e-1)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" 20.2 13.5 8.7 23.5 11.7 40.8 23.5 14.2 13.2 18.0 15.3 14.6 17.8 11.2 19.2 17.5 18.6 17.3 17.1 18.2 7.8 8.0 12.8 20.1 20.7 17.4 11.4 8.7 25.5 19.0 25.7 23.6 20.7 12.7 18.6 15.2 17.8 17.4 25.0 35.2 18.5 15.7 20.8 10.4 18.3 16.0 57.0 10.6 27.5 20.9 15.0 26.6 22.6 19.3 8.9 9.9 24.9 10.0 6.1 13.2 8.7 29.8 23.4 19.3 21.3 21.4 17.6 17.0 21.3 24.9 29.3 26.4 25.7 37.1 29.2 10.1 25.5 32.2 33.9 21.0 40.0 20.7 24.5 31.3 19.2 17.6 18.0 39.9 26.4 20.0 14.5 16.1 29.4 22.7 38.9 23.5 31.1 12.2 40.1 13.0 24.4 18.0 24.5 23.5 14.0 16.7 23.6 17.8 11.9 30.9 25.1 14.2 15.4 15.7 16.6 23.5 20.4 25.6 19.4 14.2 24.2 31.0 15.9 17.2 24.7 19.1 7.9 15.5 11.0 10.0 11.0 8.9 10.7 9.7 9.9 7.8 12.2 10.5 24.9 6.1 6.3 2.7 13.2 8.7 8.7 11.7 14.2 13.2 7.8 8.0 11.4 8.7 12.7 10.6 PABPC1 "PAB1, PABP1, PABPC2, PABPL1" ENSG00000070756 "Poly(A) binding protein cytoplasmic 1" P11940 8 100685816-100722809 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011536, HPA045423, HPA067156" Supported Supported Cytosol 2700000 Cytosol "CAB011536: AB_777008, HPA045423: , HPA067156: " "unprognostic (5.00e-2)" "unprognostic (2.64e-2)" "unprognostic (3.18e-1)" "unprognostic (4.50e-1)" "prognostic favourable (2.51e-4)" "unprognostic (1.93e-2)" "prognostic unfavourable (5.80e-4)" "unprognostic (2.51e-3)" "unprognostic (5.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.21e-3)" "unprognostic (7.24e-2)" "prognostic unfavourable (5.70e-12)" "unprognostic (6.22e-2)" "unprognostic (2.55e-1)" "unprognostic (6.98e-3)" "unprognostic (1.40e-2)" 85.6 49.6 33.6 66.1 38.8 94.2 80.5 35.8 32.5 84.2 80.7 41.9 57.2 64.1 85.3 48.8 195.5 54.6 56.4 35.1 32.3 19.3 43.6 83.2 72.8 156.2 40.6 24.3 111.1 106.9 31.8 34.1 50.6 36.8 88.2 71.5 43.4 192.9 79.0 35.1 95.4 104.0 89.9 65.2 135.3 73.4 98.7 37.6 137.2 65.4 63.0 157.9 120.9 116.4 70.8 98.4 32.3 106.7 65.9 106.0 90.6 180.2 45.1 35.3 64.1 66.2 131.6 61.0 44.1 63.9 47.5 51.8 53.9 84.9 228.8 172.1 77.6 70.0 55.3 86.3 81.3 69.9 36.5 118.0 34.0 69.3 82.1 50.5 83.5 122.2 136.7 44.2 217.6 74.2 99.1 88.1 70.4 52.5 251.4 105.3 79.1 64.1 83.0 42.9 82.6 57.4 117.4 49.3 54.9 29.4 46.0 103.0 82.8 83.8 69.1 42.8 79.9 62.8 74.2 86.4 59.8 128.2 50.4 113.5 43.0 27.6 83.3 28.8 39.7 99.9 84.2 70.8 78.3 64.4 98.4 62.6 106.0 85.1 32.3 65.9 106.7 65.5 67.4 90.6 33.6 38.8 35.8 32.5 32.3 19.3 40.6 24.3 36.8 37.6 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA015629: AB_1855012, HPA059373: " "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 24.3 14.8 13.8 20.6 15.9 17.2 24.4 19.1 13.8 18.9 18.5 14.0 22.9 12.2 25.9 13.9 19.9 18.9 13.7 15.9 11.1 10.0 11.7 14.5 14.9 16.5 16.5 8.2 25.1 15.4 14.4 30.6 28.0 14.7 16.1 15.3 12.7 17.5 16.2 21.8 17.2 14.3 21.1 15.6 19.1 14.8 13.1 13.7 51.0 22.0 10.5 17.1 22.4 23.0 6.6 10.7 11.1 8.7 4.6 7.4 1.9 12.3 8.0 28.6 14.0 14.1 14.4 20.0 17.0 11.8 19.7 17.3 8.9 8.4 30.0 2.4 20.0 8.5 24.8 12.9 24.0 32.0 13.3 28.4 15.0 6.9 20.2 23.6 21.6 13.4 14.9 22.0 14.2 19.0 16.2 16.5 19.8 4.1 39.0 7.1 17.3 13.1 20.4 17.9 15.2 8.2 24.2 19.4 21.5 20.5 4.9 16.2 9.2 13.7 21.9 18.5 14.0 15.9 20.8 11.9 18.8 28.5 11.4 19.2 18.4 10.1 5.0 11.1 4.8 3.2 4.9 3.6 4.8 5.3 4.8 6.6 7.4 4.7 2.7 4.6 8.7 10.7 4.5 1.9 13.8 15.9 19.1 13.8 11.1 10.0 16.5 8.2 14.7 13.7 PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087454-70089203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Supported Enhanced "Nuclear speckles,Cytoplasmic bodies" 12000000 "Nuclear speckles" "Cytoplasmic bodies" "CAB037113: AB_1840915, HPA043803: , HPA068497: " "unprognostic (1.63e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (7.08e-2)" "unprognostic (5.37e-1)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (9.94e-3)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.77e-1)" "prognostic favourable (1.71e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" 52.7 57.6 34.4 49.7 36.7 79.5 149.6 33.3 39.9 38.8 47.2 32.4 45.7 41.1 54.1 39.3 55.6 39.3 45.4 55.1 34.0 31.2 41.6 69.5 46.3 77.8 43.5 29.8 42.3 88.3 42.8 30.5 52.7 37.5 36.3 31.2 29.6 47.9 42.0 149.0 41.5 39.6 59.7 39.1 52.0 43.2 31.6 42.1 91.0 43.8 59.9 48.4 49.6 148.0 15.1 29.2 49.6 32.1 31.6 30.3 28.9 61.4 63.5 54.9 42.8 59.3 45.4 88.5 46.1 42.7 45.8 38.6 73.5 41.4 84.6 23.8 52.3 55.1 64.4 67.2 47.0 60.3 49.7 67.6 38.9 112.2 66.9 55.9 65.1 39.5 43.9 37.7 52.7 58.1 69.1 62.7 57.4 76.4 72.0 84.1 55.4 42.0 58.3 60.1 84.8 62.2 63.7 52.2 42.0 37.9 77.8 54.5 46.2 50.9 53.3 43.1 54.1 36.4 58.1 83.6 85.8 85.9 45.6 77.7 52.9 12.6 30.8 45.5 30.3 32.1 27.8 15.1 23.7 26.0 29.2 14.4 24.2 26.9 49.6 31.6 26.7 21.0 27.7 28.9 34.4 36.7 33.3 39.9 34.0 31.2 43.5 29.8 37.5 42.1 PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922840-18029944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Enhanced "Nuclear membrane,Centrosome,Cytosol" Centrosome "Nuclear membrane, Cytosol" "CAB058695: , HPA023370: AB_1855072, HPA023374: AB_1855073" "unprognostic (1.52e-2)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (3.35e-2)" "unprognostic (9.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.74e-3)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.83e-1)" "unprognostic (1.76e-2)" "unprognostic (2.16e-1)" "unprognostic (4.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" 19.6 19.0 26.2 26.7 40.4 25.1 25.1 29.2 29.0 25.0 21.1 21.6 22.8 12.4 23.3 27.3 16.4 26.4 17.8 23.0 22.9 18.4 18.8 22.0 19.1 21.1 24.5 24.9 29.1 27.0 42.0 35.8 19.8 26.4 20.2 16.3 16.2 19.4 25.3 63.1 17.6 18.3 26.7 27.2 20.8 17.9 80.0 28.0 40.2 28.2 19.1 20.4 27.0 22.6 11.5 14.9 19.9 7.5 11.2 13.0 4.3 20.3 21.7 33.4 44.2 18.9 19.7 17.3 17.2 21.2 18.4 20.8 14.7 12.2 26.7 11.9 17.1 14.8 21.3 15.8 31.4 8.8 8.2 45.8 15.4 29.8 21.1 20.0 11.8 17.1 16.9 21.3 23.7 21.1 30.9 20.8 22.4 10.2 42.9 33.2 27.5 6.3 25.9 29.9 9.5 15.2 28.3 25.6 19.3 18.4 10.1 26.4 15.9 29.3 18.8 16.8 13.7 20.5 14.5 8.9 19.6 23.9 14.2 22.1 17.1 19.9 6.0 14.4 11.5 3.8 12.0 11.1 10.4 13.0 5.9 11.5 11.6 11.6 6.4 11.2 7.5 14.9 10.3 4.3 26.2 40.4 29.2 29.0 22.9 18.4 24.5 24.9 26.4 28.0 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229097-54298247 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 81.5" "Cell line enhanced" "Detected in some" "ASC diff: 81.0;ASC TERT1: 37.9;BJ hTERT+: 47.0;fHDF/TERT166: 32.7;HHSteC: 27.4;HSkMC: 68.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" 150000 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: " "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favourable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavourable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 35.0 12.4 12.6 16.1 7.6 0.9 17.2 2.4 20.1 33.2 19.1 9.2 6.4 9.6 27.6 14.6 21.9 22.5 16.2 15.3 8.9 7.4 22.8 8.4 24.1 26.9 9.2 4.0 81.5 6.8 1.6 2.1 25.1 7.2 18.6 15.2 19.2 8.5 8.3 11.9 7.0 17.4 19.7 8.8 51.6 13.6 19.0 9.3 0.5 11.3 12.8 4.3 35.9 24.6 0.9 0.4 2.5 0.4 0.3 0.8 0.3 0.0 0.0 0.2 0.1 81.0 37.9 0.1 4.2 47.0 0.0 0.1 11.2 0.0 0.1 0.1 32.7 0.1 3.2 0.0 0.0 0.4 0.1 0.1 0.1 0.2 27.4 0.0 0.0 68.9 0.0 5.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.3 0.1 6.6 0.0 0.1 0.0 0.1 0.0 0.1 14.8 0.5 16.2 0.0 0.0 0.0 0.1 0.4 0.0 0.3 2.5 0.4 0.2 0.5 0.2 0.2 0.6 0.8 0.4 0.0 0.9 0.7 0.4 2.3 0.3 0.3 0.4 0.2 0.3 12.6 7.6 2.4 7.3 8.9 7.4 9.2 4.0 7.2 9.3 PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373253-134428791 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease mutation, Epilepsy, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA001023: AB_1079606" "unprognostic (2.38e-3)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.04e-3)" "unprognostic (6.03e-3)" "unprognostic (5.20e-3)" "prognostic unfavourable (3.38e-4)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (9.96e-4)" "unprognostic (1.09e-1)" "unprognostic (5.96e-2)" "unprognostic (4.84e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" 7.4 19.3 10.2 14.1 12.2 6.5 9.7 18.2 13.5 8.7 8.0 11.6 20.3 7.8 9.0 30.1 11.5 7.3 6.1 7.2 11.0 11.1 9.9 7.5 8.4 20.4 12.5 9.3 30.7 10.4 24.1 18.1 8.2 13.3 8.6 9.5 5.4 11.3 16.8 6.2 7.4 10.2 8.1 17.1 17.8 8.1 8.3 14.4 30.2 11.8 6.0 25.0 8.9 9.8 18.4 11.0 5.3 7.4 9.6 9.9 5.0 11.3 9.4 41.3 16.9 7.7 9.9 7.8 11.4 9.1 12.2 15.2 5.6 11.8 18.2 26.2 6.9 10.2 28.8 12.9 20.6 14.8 13.4 17.6 16.1 6.4 8.3 17.5 9.8 6.5 9.8 13.3 16.6 17.0 12.9 9.0 14.9 7.4 28.2 8.7 12.6 12.7 27.9 15.1 13.8 13.0 13.7 14.3 16.9 8.7 8.1 11.9 7.5 9.7 12.9 11.4 8.2 14.3 17.4 4.6 10.7 24.6 7.5 20.9 14.2 5.3 6.1 3.7 7.9 6.0 8.5 18.4 8.2 7.1 8.8 12.8 9.9 8.2 2.5 9.6 7.4 11.0 8.3 5.0 10.2 12.2 18.2 13.5 11.0 11.1 12.5 9.3 13.3 14.4 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76033932 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "salivary gland: 142.4" "Cell line enhanced" "Detected in many" "hTERT-HME1: 43.3;RPTEC TERT1: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.4;MAIT T-cell: 3.9;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.5;non-classical monocyte: 2.5;T-reg: 4.1" "Group enriched" "Detected in many" 7 "monocytes: 2.5;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: " "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 13.2 15.9 9.4 8.4 12.1 9.0 13.5 6.4 15.7 11.5 4.5 11.1 4.8 3.4 7.1 3.1 33.3 5.1 20.0 9.6 8.2 7.9 13.8 33.2 14.2 3.0 8.4 5.6 10.8 8.8 2.6 6.0 7.1 10.0 4.8 5.5 24.9 142.4 6.5 3.3 6.3 7.0 7.6 9.7 14.6 10.8 2.3 10.1 2.5 18.0 13.2 19.9 17.0 17.8 0.3 0.1 0.4 2.5 0.3 4.1 0.6 13.5 16.3 12.8 7.0 6.0 12.4 0.9 11.5 31.1 5.2 7.3 9.0 16.6 0.0 3.5 4.8 7.0 0.3 19.3 11.3 2.0 0.2 0.3 0.8 15.2 8.7 0.3 3.5 3.8 14.2 21.8 43.3 12.5 1.1 0.4 26.8 1.7 0.0 1.7 4.6 25.2 0.0 3.3 0.4 54.9 30.8 0.9 2.4 2.0 0.1 37.4 8.2 0.1 11.6 17.9 1.7 20.8 11.3 0.2 0.0 0.0 30.2 0.2 22.3 0.3 0.1 0.2 2.4 0.2 3.9 0.3 2.5 2.5 0.0 0.2 0.5 0.6 0.4 0.3 2.5 0.1 4.1 0.6 9.4 12.1 6.4 7.7 8.2 7.9 8.4 5.6 10.0 10.1 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Approved Cytosol Cytosol "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 20.1 12.3 13.7 11.5 13.4 25.7 22.4 17.1 24.5 12.9 14.0 5.2 5.7 6.5 15.3 7.9 11.6 11.1 13.2 14.2 18.4 9.7 11.7 10.8 13.2 13.8 9.8 15.7 15.4 9.2 24.7 11.6 16.5 16.3 10.7 8.9 7.2 10.9 10.9 15.2 12.0 10.5 12.8 14.4 16.2 10.6 9.3 9.8 29.6 11.0 7.3 13.9 15.1 15.7 6.2 2.6 7.8 3.8 2.4 5.0 1.1 14.4 4.9 7.9 7.3 18.7 21.8 5.7 9.2 12.5 9.1 14.4 4.2 10.7 13.2 15.8 11.0 5.9 6.4 8.0 13.2 22.0 5.7 18.1 5.3 3.7 8.9 10.1 10.3 13.7 8.5 10.0 11.5 13.0 9.0 14.7 13.0 5.7 7.7 9.1 6.2 6.7 11.8 8.0 15.8 7.2 8.8 4.4 7.6 10.0 8.9 12.0 14.9 8.7 13.8 8.6 5.6 13.5 9.2 7.1 10.1 23.7 7.7 7.6 5.0 2.1 3.8 1.6 5.0 2.9 3.9 5.8 4.2 2.8 2.2 6.2 4.6 3.8 7.8 2.4 3.0 2.6 4.1 1.1 13.7 13.4 17.1 24.5 18.4 9.7 9.8 15.7 16.3 9.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652699-138834938 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 41.2;HMC-1: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: " "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavourable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 12.5 9.9 10.6 9.7 20.6 17.4 11.5 29.9 25.0 12.4 14.6 11.9 11.7 13.7 9.6 6.9 15.2 10.9 8.7 12.7 12.2 14.2 22.6 9.3 9.5 9.1 11.9 15.2 8.8 20.3 20.2 10.9 18.1 24.1 13.4 15.7 12.2 14.9 15.9 33.4 19.6 16.4 8.3 12.5 9.9 11.0 6.4 10.7 14.4 37.4 7.1 11.9 13.4 11.0 4.6 9.1 11.3 7.8 1.3 6.5 2.6 22.6 9.8 4.2 3.5 3.9 5.2 28.7 5.3 5.1 5.4 5.8 10.5 8.6 9.1 14.5 5.2 9.7 5.5 8.4 9.7 11.6 6.2 41.2 6.7 6.3 4.0 10.0 65.3 4.4 6.5 3.8 7.7 8.1 15.7 6.8 6.7 10.3 5.8 7.0 6.0 9.2 4.2 4.4 6.5 8.3 12.5 3.7 2.7 14.7 6.4 18.9 16.0 23.9 8.5 3.5 4.4 7.5 7.4 11.5 7.5 8.3 8.5 9.7 4.8 7.0 7.8 11.3 4.0 4.5 2.7 4.6 5.2 3.0 9.1 4.1 6.5 4.4 10.0 1.3 4.3 1.4 2.2 2.6 10.6 20.6 29.9 25.0 12.2 14.2 11.9 15.2 24.1 10.7 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106907145 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 24.5;bone marrow: 27.8;lymphoid tissue: 40.8" "Cell line enhanced" "Detected in some" "Daudi: 12.2;HMC-1: 15.2;Karpas-707: 12.6;MOLT-4: 23.0;U-266/70: 30.9;U-937: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA069976: " "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 5.0 1.8 2.2 16.0 3.1 27.8 2.3 0.8 1.7 1.7 4.1 2.7 0.0 2.8 1.7 2.0 2.0 1.8 3.5 1.7 1.7 1.5 1.9 1.5 4.3 13.1 3.0 1.0 1.7 1.5 0.6 1.4 2.0 2.5 2.2 2.6 1.9 3.1 0.5 1.1 1.3 6.1 1.9 6.4 17.4 2.5 7.6 3.0 40.8 2.3 0.9 21.2 4.1 1.5 6.2 5.6 14.2 24.5 5.3 5.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 11.9 15.2 0.0 0.0 0.0 0.0 4.7 8.5 12.6 0.0 0.0 23.0 4.6 0.0 0.0 6.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 1.2 0.0 0.1 0.0 0.0 30.9 0.0 11.5 0.0 21.8 2.9 4.6 3.4 14.2 5.6 10.6 5.1 4.7 2.6 4.2 5.6 6.2 2.8 3.8 13.9 5.3 24.5 4.9 2.6 3.6 2.2 3.1 0.8 1.7 1.7 1.5 3.0 1.0 2.5 3.0 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215720-68301821 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favourable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 26.2 13.4 26.0 13.0 24.3 51.6 42.3 15.3 50.3 27.1 20.3 12.8 12.8 8.1 41.3 22.1 20.8 33.0 18.1 33.9 24.0 13.4 17.9 46.5 16.3 12.0 22.0 40.8 25.8 6.8 22.3 9.4 15.0 18.2 15.2 10.8 8.7 54.6 16.2 48.9 19.1 16.1 36.3 17.6 18.8 13.1 7.6 23.6 16.2 12.8 8.5 10.8 25.2 24.4 2.2 2.1 10.6 4.1 8.2 14.8 4.0 1.0 2.1 6.3 18.7 71.7 21.0 2.7 6.0 2.8 2.3 2.5 5.2 1.9 5.5 10.3 8.2 2.6 1.7 12.1 2.9 23.0 2.3 6.6 1.7 4.2 24.1 6.7 5.3 22.1 27.6 4.2 22.5 3.0 1.0 4.2 2.1 2.8 16.4 2.6 1.8 1.1 15.4 3.0 4.3 3.0 12.3 1.2 5.7 0.9 1.6 3.9 9.0 4.8 3.6 2.7 2.8 4.5 3.7 4.7 7.0 6.4 2.9 8.5 2.0 10.6 1.2 5.9 9.2 1.7 12.7 1.2 11.5 8.4 2.1 2.2 14.8 10.8 1.5 8.2 4.1 0.9 8.5 4.0 26.0 24.3 15.3 50.3 24.0 13.4 22.0 40.8 18.2 23.6 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavourable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 18.1 19.5 15.7 15.4 21.0 9.6 20.2 22.6 27.6 19.8 18.0 20.3 14.7 16.4 24.8 22.6 20.7 19.4 20.7 18.9 17.3 13.4 17.8 18.3 21.7 17.1 12.7 17.5 20.4 16.6 21.8 25.3 44.6 14.6 17.3 15.6 29.5 17.8 15.2 26.1 20.4 20.4 27.2 16.1 20.1 16.8 42.1 14.0 19.3 20.1 13.9 22.3 16.2 17.7 9.1 8.7 11.7 6.2 4.7 5.9 6.3 17.7 13.8 21.4 24.6 14.1 14.9 21.0 23.4 33.0 43.8 39.3 25.1 17.2 16.1 25.0 24.9 15.1 27.7 16.1 38.4 24.3 19.8 12.8 18.2 11.9 26.7 22.9 16.2 19.9 14.9 27.2 34.5 17.8 12.5 13.8 22.0 24.8 22.8 11.4 31.7 21.4 22.1 18.7 12.0 22.5 10.3 14.3 19.0 31.6 24.4 20.6 25.5 21.7 17.0 17.4 24.4 16.0 28.1 19.3 32.1 36.4 16.9 6.7 20.8 0.1 5.5 7.3 5.3 6.2 4.1 9.1 5.0 5.9 8.4 4.6 5.4 4.2 11.7 4.7 4.8 8.7 3.9 6.3 15.7 21.0 22.6 27.6 17.3 13.4 12.7 17.5 14.6 14.0 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 5.9;MAIT T-cell: 8.0;memory CD4 T-cell: 5.2;memory CD8 T-cell: 4.9;naive CD4 T-cell: 5.7;naive CD8 T-cell: 5.4;NK-cell: 4.0;T-reg: 4.4" "Group enriched" "Detected in many" 8 "NK-cells: 4.0;T-cells: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol Cytosol "CAB004277: AB_628119, HPA036681: , HPA036682: " "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favourable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 20.2 15.1 25.1 20.9 22.1 8.3 34.9 52.6 26.8 19.9 13.9 23.4 12.5 16.5 27.6 13.9 13.5 17.0 18.7 20.9 25.4 13.6 15.3 6.8 19.3 30.7 18.5 20.5 28.7 9.1 16.9 14.2 22.2 18.7 18.4 13.2 20.0 13.2 20.6 13.4 22.3 17.1 22.2 15.4 20.1 12.4 19.9 23.9 48.1 28.5 11.9 21.9 17.1 21.1 0.7 0.0 0.0 0.0 4.0 8.0 3.3 5.3 6.8 32.9 24.1 13.2 9.3 10.5 8.8 11.4 17.8 15.2 16.4 1.8 12.0 10.9 9.6 10.0 14.3 15.8 10.4 3.4 7.6 0.8 11.4 19.3 10.0 4.7 3.3 11.8 8.9 13.1 10.3 19.9 8.9 7.9 16.1 40.1 28.9 3.7 12.2 12.6 23.1 24.0 5.9 9.8 9.9 11.7 22.4 15.8 7.4 15.9 8.6 5.5 21.4 42.7 13.9 13.6 10.7 8.9 3.9 10.0 10.2 5.1 17.7 0.0 0.0 0.0 5.9 0.0 8.0 0.3 5.2 4.9 0.0 0.7 5.7 5.4 0.0 4.0 0.0 0.0 4.4 3.3 25.1 22.1 52.6 26.8 25.4 13.6 18.5 20.5 18.7 23.9 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915147-143976734 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease mutation, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 144.9" "Cell line enhanced" "Detected in many" "PC-3: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Enhanced "Intermediate filaments,Focal adhesion sites,Cytosol" 7100000 "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavourable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavourable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 20.9 11.0 15.9 16.5 13.3 27.9 13.1 15.0 20.7 20.7 17.7 14.6 16.7 13.1 20.2 16.8 25.1 18.2 29.0 23.4 18.9 10.7 11.2 10.9 16.6 15.0 9.9 13.0 18.0 14.0 8.8 12.0 24.2 13.2 17.5 9.8 13.0 17.8 14.8 144.9 36.4 24.1 24.7 11.0 16.9 21.4 6.7 12.7 16.3 9.2 44.2 24.5 20.2 19.2 1.5 3.4 0.8 4.1 0.7 2.9 3.2 16.3 51.2 3.3 4.1 6.0 13.4 11.7 24.0 10.7 6.4 3.6 7.1 17.1 1.6 18.7 35.1 19.4 2.2 33.6 2.5 12.2 1.8 6.2 52.0 5.8 9.5 2.0 5.2 15.4 6.6 17.2 33.6 7.4 3.0 5.3 7.4 28.7 1.2 3.4 2.2 72.1 0.3 9.4 4.4 10.7 30.3 3.4 3.4 40.9 8.7 3.9 10.7 2.4 23.8 24.8 44.9 21.8 28.4 0.8 0.6 1.2 23.6 2.6 35.2 0.0 4.1 0.2 1.4 3.8 2.8 1.4 2.7 2.0 3.4 1.5 2.0 1.1 0.8 0.7 2.7 2.8 2.9 3.2 15.9 13.3 15.0 17.3 18.9 10.7 9.9 13.0 13.2 12.7 POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130074030-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 5.7" "Cell line enhanced" "Detected in some" "AN3-CA: 4.3;BEWO: 3.5;CACO-2: 4.0;MCF7: 2.9;U-2 OS: 9.6;U-266/70: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271, HPA043260" Uncertain "HPA041264: , HPA041271: , HPA043260: " "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (8.13e-3)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" "unprognostic (4.48e-1)" "unprognostic (1.05e-2)" "unprognostic (9.35e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.1 0.7 0.7 0.7 0.2 0.5 1.1 0.2 0.2 0.0 4.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.3 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 9.6 0.1 0.2 4.6 1.3 0.0 0.0 0.0 0.0 0.5 0.6 0.7 0.4 0.7 0.1 0.1 0.2 0.3 0.7 0.1 0.1 0.3 0.6 0.2 0.7 0.1 0.5 1.1 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190039-52229533 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol 3400000 Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavourable (1.76e-4)" "prognostic unfavourable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favourable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 25.3 57.3 60.7 20.5 71.0 18.0 21.4 47.5 82.1 29.6 31.2 26.6 21.5 33.4 26.4 37.9 37.7 47.0 39.9 74.7 70.2 44.8 31.0 29.3 20.0 27.5 44.0 50.9 45.8 24.3 37.8 29.5 24.6 51.0 31.0 29.8 31.0 24.3 35.6 50.6 33.5 25.3 34.5 25.2 20.5 19.8 21.7 18.1 29.0 28.9 35.9 30.6 27.3 23.1 52.8 62.8 51.9 67.2 69.8 56.3 67.8 30.4 51.7 41.3 36.7 33.6 35.2 21.7 25.7 33.7 34.4 30.0 26.0 24.1 26.7 18.5 40.8 22.0 44.2 38.7 20.0 19.7 119.9 19.6 28.5 29.2 30.7 21.1 18.7 47.2 32.1 32.1 29.6 32.6 22.7 18.8 38.0 35.2 29.5 40.3 40.9 45.7 29.0 24.0 29.8 55.2 50.2 31.2 33.4 31.4 31.4 19.1 28.4 37.3 30.9 27.3 24.6 13.3 29.3 19.5 28.5 31.3 29.3 21.4 34.3 45.0 55.3 51.9 50.4 67.2 45.8 48.4 45.1 47.1 62.8 52.8 37.7 43.0 33.7 69.8 59.8 39.0 56.3 67.8 60.7 71.0 47.5 82.1 70.2 44.8 44.0 50.9 51.0 18.1 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol 11000000 Cytosol "CAB019378: , HPA049979: " "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 47.1 48.0 41.7 34.5 54.8 14.6 38.7 40.4 57.4 48.2 23.8 44.9 31.4 15.1 43.6 37.7 29.6 43.2 37.4 122.7 42.5 52.3 49.2 43.4 47.3 29.5 50.1 43.6 62.5 19.1 107.8 41.9 47.3 57.7 35.6 24.2 32.2 47.5 43.6 99.8 22.8 19.3 39.4 52.8 35.3 25.1 36.9 40.1 28.2 51.8 23.6 29.2 33.8 33.4 11.3 26.9 52.6 28.7 18.5 13.0 22.9 16.4 31.6 40.6 24.3 54.2 61.6 6.1 22.2 45.8 34.7 30.7 12.3 22.2 16.7 15.3 48.4 13.6 30.0 36.0 49.9 11.3 10.7 25.8 27.5 40.2 39.3 19.7 29.0 44.0 37.4 40.0 33.8 57.6 11.6 26.3 42.0 31.1 21.7 10.6 15.0 21.6 15.2 67.3 18.4 52.6 35.8 14.8 20.0 20.3 37.2 85.5 29.0 27.9 40.8 49.0 23.4 22.1 20.6 21.9 15.5 24.9 29.6 18.8 30.5 31.1 26.1 46.3 13.0 25.5 13.0 11.3 9.8 11.6 26.9 8.5 8.9 9.8 52.6 18.5 28.7 8.8 12.3 22.9 41.7 54.8 40.4 57.4 42.5 52.3 50.1 43.6 57.7 40.1 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 63.3;THP-1: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavourable (2.24e-4)" "prognostic favourable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.7 3.0 1.2 2.0 9.0 5.2 11.2 4.7 5.9 5.8 5.7 7.3 7.6 20.0 2.1 10.2 3.5 7.9 11.5 4.7 17.4 6.0 11.1 4.1 7.8 5.7 14.6 25.1 4.1 8.4 5.9 5.5 5.0 2.2 2.9 8.3 19.1 1.6 24.9 3.1 5.5 1.7 3.0 4.7 6.3 16.7 2.0 1.4 3.6 63.3 9.7 5.3 45.2 7.2 2.8 3.6 3.7 4.4 4.4 6.8 10.2 6.7 25.2 5.4 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684882 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457" Supported Enhanced Nucleoplasm 240000 Nucleoplasm "CAB009941: AB_2171185, CAB015457: AB_831685" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (1.56e-1)" "unprognostic (4.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" 30.0 37.4 23.1 25.7 40.3 39.0 26.2 43.1 57.2 31.2 28.0 36.5 29.5 19.4 35.6 28.4 29.4 35.4 28.1 34.0 22.2 24.3 23.3 35.5 27.9 30.7 21.3 23.9 47.7 25.9 66.5 45.4 31.1 32.5 30.7 27.2 45.1 30.5 33.1 46.3 30.7 27.5 36.3 17.9 34.1 26.4 45.9 19.6 63.4 30.9 22.2 41.2 32.2 27.9 14.5 20.1 10.0 12.3 10.1 17.1 5.4 18.4 40.2 24.2 19.6 21.0 16.4 19.5 13.8 17.7 27.1 21.9 37.3 9.1 27.1 14.7 24.8 25.7 59.1 23.7 31.3 17.1 37.9 21.5 34.9 31.8 12.3 25.4 23.9 15.6 15.2 34.9 24.4 23.8 21.2 21.6 19.4 20.1 18.3 31.8 16.7 14.9 36.0 13.8 13.0 10.4 20.5 12.4 18.7 27.8 10.1 13.6 14.9 17.0 21.9 16.5 14.2 25.2 31.5 7.9 8.1 19.1 13.7 18.4 20.4 10.0 6.5 6.7 15.7 8.9 17.1 13.3 14.7 15.7 9.7 14.5 13.0 16.4 7.1 10.1 12.3 20.1 14.8 5.4 23.1 40.3 43.1 57.2 22.2 24.3 21.3 23.9 32.5 19.6 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: " "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favourable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 16.3 15.3 21.0 13.4 34.9 19.2 15.7 15.5 24.7 16.5 26.2 66.1 9.5 26.6 14.2 15.4 19.0 12.6 17.1 9.9 28.6 18.2 19.7 16.9 16.9 10.8 42.1 20.7 13.5 15.0 21.8 9.2 22.7 31.8 13.6 25.6 15.0 16.8 13.4 13.0 24.7 27.9 14.6 61.9 14.6 16.3 16.8 39.7 15.4 19.7 8.7 15.9 17.2 13.5 9.0 24.4 38.1 34.0 11.7 10.5 17.1 14.2 21.9 20.5 8.1 28.7 20.5 18.7 21.0 24.1 21.5 27.2 27.2 35.7 9.3 13.9 19.9 38.0 17.2 15.9 23.6 21.2 10.7 10.6 14.9 13.2 26.5 10.7 20.8 21.0 28.9 17.8 22.0 17.2 11.8 19.0 20.1 28.3 8.1 13.9 8.9 16.3 10.3 17.4 11.8 30.0 30.3 11.4 15.2 22.9 21.5 18.7 26.6 23.9 18.2 21.9 18.1 17.9 9.9 12.4 18.2 9.4 18.4 13.0 13.3 29.2 27.1 27.1 7.2 30.8 7.0 7.2 7.0 5.9 24.4 9.0 6.6 6.4 38.1 11.7 34.0 12.8 10.5 17.1 21.0 34.9 15.5 24.7 28.6 18.2 42.1 20.7 31.8 39.7 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: " "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavourable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.4 4.9 5.7 5.1 13.1 9.0 5.1 5.6 12.5 6.6 9.3 5.0 12.9 12.3 3.8 9.2 6.3 7.5 6.4 10.5 6.2 2.1 4.1 12.8 6.1 14.0 13.8 7.1 6.1 17.9 8.3 10.8 9.3 3.1 33.6 6.0 8.0 7.7 25.1 2.1 0.0 12.0 3.0 9.1 10.3 6.0 2.0 9.2 7.5 3.5 9.4 9.9 20.0 8.1 21.9 5.1 8.5 4.5 11.1 14.3 14.1 6.8 13.1 1.3 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" 160000 Nucleoli "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 34.8 33.3 24.3 23.0 35.4 34.6 28.8 42.4 46.3 33.4 25.2 33.1 13.5 36.9 22.1 39.2 20.9 31.2 37.6 55.7 28.0 25.7 53.7 31.0 18.1 35.4 43.0 34.3 28.0 37.9 35.9 51.1 27.6 40.7 13.0 32.2 25.2 30.2 20.9 29.4 21.8 31.1 35.9 21.2 30.8 39.2 16.9 20.8 40.8 31.3 26.0 36.0 29.9 33.6 39.4 35.3 23.4 37.1 25.2 41.5 36.9 32.7 30.2 36.8 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374523-6403977 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol 44000000 "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: " "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavourable (1.74e-5)" "prognostic unfavourable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavourable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 45.2 35.0 71.0 28.4 64.0 24.4 46.5 42.1 93.0 48.7 58.9 75.5 22.5 51.6 48.7 49.5 93.4 47.2 40.0 48.4 73.8 59.8 47.8 42.9 45.6 38.3 76.7 60.9 45.1 29.2 51.0 25.2 55.8 54.9 40.5 64.0 37.2 43.3 48.9 57.4 58.6 49.8 57.3 88.2 35.0 49.7 28.1 47.1 41.3 40.9 42.8 50.7 52.2 54.0 11.0 32.0 49.1 31.9 7.3 11.8 10.7 73.9 33.6 34.7 37.7 41.2 52.7 20.7 41.7 51.3 55.7 56.8 32.9 70.0 20.9 27.1 58.2 52.8 37.0 50.6 71.4 9.7 30.7 21.0 27.2 23.8 49.6 18.9 17.2 35.1 45.3 40.1 45.0 49.0 37.4 16.5 60.0 53.9 10.4 44.4 62.2 40.3 18.4 35.3 30.6 71.6 46.9 26.3 44.3 29.4 107.9 33.5 60.8 56.9 51.4 36.6 55.1 44.8 48.1 12.6 13.8 19.6 33.7 36.1 69.3 7.6 31.9 16.4 7.2 22.2 4.5 11.0 8.1 9.2 32.0 11.0 9.8 6.5 49.1 7.3 22.1 18.2 11.8 10.7 71.0 64.0 42.1 93.0 73.8 59.8 76.7 60.9 54.9 47.1 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845935-116874866 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065" Supported Enhanced Nucleoplasm Nucleoplasm "CAB022065: , HPA020044: AB_1856035" "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavourable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 31.6 40.9 48.2 30.5 52.2 78.5 37.7 58.8 55.3 24.2 36.3 37.5 21.5 24.8 30.5 25.3 32.1 23.1 22.0 37.8 45.6 44.1 30.5 27.9 29.6 49.2 54.3 35.4 33.5 18.2 29.1 30.0 38.9 45.5 26.5 37.3 19.0 25.3 31.0 37.8 24.0 26.0 33.4 49.7 31.2 31.5 37.6 56.2 58.3 41.9 20.9 50.4 37.1 36.0 8.7 5.4 17.9 7.1 8.0 25.4 6.2 42.6 21.0 41.1 23.1 20.7 17.9 18.4 29.7 28.2 33.0 30.5 17.2 40.3 63.1 16.4 21.1 23.8 35.0 19.1 38.7 83.7 22.5 64.3 25.8 21.9 13.0 20.6 37.9 15.2 15.7 19.3 23.4 25.8 25.8 88.4 28.4 25.7 94.3 12.1 24.1 26.5 34.6 29.9 31.7 19.6 25.1 52.0 26.8 31.1 84.0 20.0 35.2 25.5 18.8 23.3 34.2 24.4 31.1 46.8 53.8 56.8 19.9 29.7 27.9 17.2 4.5 15.5 11.0 5.3 11.2 8.7 12.9 13.0 5.4 8.3 13.5 13.0 17.9 8.0 7.1 4.5 25.4 6.2 48.2 52.2 58.8 55.3 45.6 44.1 54.3 35.4 45.5 56.2 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719481-108785811 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Enhanced "Nuclear membrane,Vesicles" "Nuclear membrane, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.5 24.3 14.4 17.0 18.6 35.5 24.4 23.1 22.2 19.8 17.1 12.8 25.5 13.3 19.9 21.5 17.0 19.1 14.8 20.2 12.9 12.5 18.9 19.5 17.7 19.2 15.1 17.0 32.4 24.1 48.5 37.5 18.8 16.5 21.8 15.8 14.3 20.0 31.6 37.5 17.3 17.4 23.2 17.8 16.3 20.9 20.6 15.9 26.6 28.7 18.0 17.5 20.5 19.7 5.6 5.1 8.3 6.3 4.2 8.7 2.3 18.2 11.2 16.1 14.6 18.8 16.9 15.6 16.5 13.1 13.6 12.0 27.8 8.8 28.8 12.8 17.1 15.4 27.5 17.1 19.9 17.5 13.3 30.0 13.9 19.6 11.0 35.0 10.1 14.1 13.1 21.3 16.6 20.8 32.1 16.0 18.0 10.1 15.5 14.3 20.3 13.4 14.6 24.8 13.9 12.1 22.9 23.5 10.8 14.6 12.6 16.0 8.0 16.1 24.8 14.3 18.9 10.0 18.4 13.3 19.6 26.2 11.1 15.8 11.0 8.3 5.3 5.1 7.6 3.4 8.7 5.5 6.3 6.9 4.2 5.6 6.2 6.7 8.3 4.2 6.3 5.1 5.1 2.3 14.4 18.6 23.1 22.2 12.9 12.5 15.1 17.0 16.5 15.9 RANBP3 ENSG00000031823 "RAN binding protein 3" Q9H6Z4 19 5916139-5978142 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043375, HPA043389" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA043375: AB_10959889, HPA043389: AB_10963696" "unprognostic (1.81e-1)" "unprognostic (1.18e-3)" "unprognostic (3.61e-1)" "prognostic favourable (1.22e-5)" "unprognostic (4.24e-2)" "unprognostic (1.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-1)" "prognostic favourable (4.14e-4)" "unprognostic (2.27e-1)" "unprognostic (3.80e-2)" "unprognostic (2.91e-1)" "unprognostic (5.15e-2)" "prognostic favourable (8.14e-4)" "unprognostic (1.06e-2)" 19.5 30.2 24.8 25.2 31.5 20.9 18.6 38.2 40.9 21.2 29.8 31.6 18.3 24.7 28.2 16.5 23.4 23.9 20.3 30.8 25.0 26.5 19.3 24.6 21.9 26.7 24.3 21.2 29.2 33.1 22.4 26.1 22.3 28.8 25.6 14.2 30.1 27.9 28.0 33.9 21.2 25.1 27.9 25.0 24.9 24.9 36.7 28.0 33.5 21.9 14.7 27.7 28.0 20.9 20.7 21.3 25.0 21.4 14.9 28.7 20.1 30.3 21.4 18.2 20.3 13.7 14.0 13.0 19.4 18.4 22.8 24.7 26.9 10.8 28.7 21.9 15.0 18.9 16.2 18.9 14.0 29.3 26.4 15.4 16.7 32.0 14.9 22.4 22.6 13.6 13.1 14.2 16.3 16.6 27.8 27.2 12.8 12.7 37.3 10.9 33.3 27.1 27.7 17.5 26.1 14.8 23.5 20.1 22.6 17.3 18.3 17.1 14.0 17.1 17.1 19.3 14.1 33.6 28.5 28.2 28.4 24.7 24.4 28.3 23.6 13.2 20.8 25.0 22.7 21.4 23.3 17.0 22.0 22.7 21.3 20.7 19.6 25.1 24.0 14.9 20.6 20.2 28.7 20.1 24.8 31.5 38.2 40.9 25.0 26.5 24.3 21.2 28.8 28.0 RASA1 "CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA" ENSG00000145715 "RAS p21 protein activator 1" P20936 5 87267888-87391931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 13 "placenta: 260.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007789, HPA036393, HPA064556" Enhanced 7900 "CAB007789: AB_598183, HPA036393: , HPA064556: " "unprognostic (1.57e-1)" "unprognostic (7.63e-2)" "unprognostic (1.88e-3)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.38e-2)" "unprognostic (6.88e-2)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (1.07e-2)" "unprognostic (4.12e-3)" "unprognostic (1.03e-1)" "unprognostic (3.98e-2)" "unprognostic (1.59e-2)" "unprognostic (5.39e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-3)" 12.4 8.8 12.3 8.9 12.8 6.4 11.4 17.3 16.3 11.3 8.1 8.6 9.3 6.9 12.4 11.4 10.2 9.5 9.3 7.2 12.0 10.9 8.7 6.5 8.4 9.2 10.1 13.8 15.9 8.2 20.3 12.2 260.6 9.3 8.0 9.8 9.6 10.6 9.6 6.9 9.7 10.0 9.0 9.4 13.7 7.4 14.4 10.0 10.7 14.4 5.7 9.6 11.3 9.8 2.0 1.3 3.1 2.6 8.1 3.5 1.1 11.5 6.5 11.3 7.3 9.6 14.2 8.8 18.5 12.0 11.4 18.9 4.3 30.6 7.5 4.5 20.2 5.4 5.2 15.0 34.7 7.3 4.2 5.6 5.6 4.7 9.7 4.1 6.7 8.0 9.6 32.1 18.2 15.9 3.1 16.2 39.3 7.0 5.0 6.1 5.9 12.1 6.2 25.7 11.1 9.9 10.0 6.9 7.5 6.8 8.8 9.7 7.9 6.4 23.5 14.6 6.4 7.5 23.0 5.7 5.9 7.6 21.3 8.5 10.4 3.1 1.3 1.4 2.0 2.6 3.5 1.4 2.4 1.9 1.1 2.0 2.1 1.9 1.7 8.1 2.4 1.3 3.0 1.1 12.3 12.8 17.3 16.3 12.0 10.9 10.1 13.8 9.3 10.0 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303726-48599436 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: " "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 19.6 21.5 14.9 23.2 18.4 14.7 28.1 25.6 19.4 18.0 13.2 11.5 19.0 12.3 16.8 19.5 27.9 12.7 15.3 19.5 15.4 15.3 18.1 12.1 25.4 30.1 17.0 11.8 15.2 11.6 12.8 17.2 21.5 16.0 15.5 15.3 11.6 20.0 17.4 27.9 20.3 14.3 16.8 23.6 29.4 13.7 14.4 15.3 39.1 19.9 15.8 25.3 17.4 23.6 20.5 10.3 13.2 12.2 3.6 4.6 4.0 9.0 4.9 13.4 14.4 6.6 7.7 6.1 17.9 14.9 18.9 16.1 4.2 16.1 11.7 4.1 11.9 12.6 17.4 14.4 28.9 16.4 6.6 21.6 10.1 7.1 7.1 18.5 20.5 4.3 8.9 12.2 15.7 13.0 7.1 9.7 21.6 4.3 57.9 9.3 6.5 5.4 24.9 13.4 13.5 19.6 8.8 0.6 13.7 17.7 8.9 14.6 9.7 24.2 10.1 11.7 7.7 14.3 16.1 4.3 1.2 0.1 6.2 11.6 15.8 11.0 9.7 5.0 4.6 12.2 3.7 17.4 3.8 4.6 9.3 20.5 3.2 3.8 13.2 3.6 12.1 10.3 4.5 4.0 14.9 18.4 25.6 19.4 15.4 15.3 17.0 11.8 16.0 15.3 RBMX "hnRNP-G, HNRNPG, RNMX" ENSG00000147274 "RNA binding motif protein, X-linked" P38159 X 136848004-136880764 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Cancer-related genes, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057707 Supported Approved Nucleoplasm Nucleoplasm "HPA057707: " "unprognostic (1.53e-1)" "unprognostic (1.52e-3)" "unprognostic (2.12e-3)" "unprognostic (1.14e-2)" "unprognostic (2.62e-2)" "unprognostic (8.13e-2)" "prognostic unfavourable (5.16e-6)" "unprognostic (5.59e-2)" "unprognostic (1.05e-2)" "unprognostic (1.68e-2)" "unprognostic (4.87e-2)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (1.57e-1)" "unprognostic (7.65e-2)" "unprognostic (6.27e-2)" "unprognostic (4.64e-3)" 31.0 25.0 30.6 57.1 41.1 48.0 40.6 28.7 33.0 44.2 28.3 32.5 32.7 24.6 45.9 31.7 26.7 38.9 22.1 31.4 26.5 18.0 25.6 20.9 34.4 64.6 34.0 29.3 81.9 39.1 30.1 30.1 25.3 30.5 28.4 33.4 27.5 29.9 29.4 50.0 27.6 27.3 43.0 44.2 27.4 30.1 23.6 29.2 70.1 31.5 34.4 44.8 36.1 33.4 47.1 41.9 25.0 44.9 39.4 60.7 62.9 39.9 43.7 80.1 35.6 20.0 34.0 46.8 39.9 43.5 55.3 58.7 46.6 40.2 72.8 41.3 28.5 26.8 85.0 41.7 64.1 31.4 40.0 55.7 43.0 49.6 17.6 60.7 51.3 27.8 20.2 43.0 60.3 44.5 49.9 37.4 44.9 50.9 88.6 41.0 50.8 36.6 73.7 53.6 44.9 41.0 47.9 46.8 50.6 31.8 28.8 36.9 33.1 41.0 28.2 31.4 34.1 21.7 50.7 26.8 35.7 77.1 22.4 44.4 42.7 25.0 37.5 20.8 36.4 44.9 50.3 47.1 47.4 43.1 41.9 45.0 60.7 49.6 6.0 39.4 39.2 25.4 46.8 62.9 30.6 41.1 28.7 33.0 26.5 18.0 34.0 29.3 30.5 29.2 RHEB RHEB2 ENSG00000106615 "Ras homolog, mTORC1 binding" Q15382 7 151466012-151520120 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019436 Uncertain 24000 "CAB019436: AB_2178777" "unprognostic (2.22e-2)" "unprognostic (2.29e-2)" "unprognostic (2.25e-2)" "unprognostic (9.47e-2)" "unprognostic (2.65e-2)" "unprognostic (3.08e-3)" "prognostic unfavourable (9.08e-5)" "unprognostic (9.37e-2)" "unprognostic (4.76e-3)" "unprognostic (9.76e-3)" "unprognostic (1.85e-3)" "unprognostic (3.67e-2)" "unprognostic (2.36e-3)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.15e-1)" 21.8 37.2 30.9 15.1 32.4 23.8 28.0 21.1 34.6 16.5 22.3 14.6 26.7 13.3 24.2 44.4 18.3 15.4 14.9 26.2 31.4 29.3 25.0 27.4 19.8 9.8 28.9 18.2 18.7 20.4 19.0 48.6 37.0 27.3 21.0 16.1 24.8 20.4 27.1 34.2 11.5 13.4 30.0 29.7 15.2 17.1 15.8 25.4 10.8 40.6 12.8 11.6 19.6 14.1 16.5 32.2 30.9 24.3 23.5 30.1 26.0 57.1 17.5 31.0 29.4 38.7 31.8 23.4 42.3 37.4 35.6 43.5 25.1 62.4 14.8 66.7 37.4 19.5 22.2 20.4 46.3 15.6 17.1 12.6 21.4 18.7 60.5 23.3 20.7 24.3 32.8 28.3 38.2 27.4 39.0 68.9 49.0 37.0 32.9 33.4 50.8 25.5 16.0 27.3 29.8 41.3 20.6 29.8 37.5 43.0 41.8 47.8 15.6 29.3 29.9 28.2 11.7 48.6 68.0 25.9 35.3 21.3 68.2 43.8 76.2 22.7 24.3 30.9 18.5 20.6 30.1 16.5 25.7 23.1 18.4 15.1 18.8 23.2 23.9 23.5 22.3 32.2 24.9 26.0 30.9 32.4 21.1 34.2 31.4 29.3 28.9 18.2 27.3 25.4 RHOA "ARH12, ARHA, Rho12, RhoA, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359145-49412998 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" 65000000 "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favourable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favourable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 141.1 89.5 63.0 79.8 60.6 91.4 93.1 34.3 77.3 80.3 79.1 100.4 48.9 63.6 84.4 66.4 116.7 67.8 74.2 72.5 57.6 54.8 104.0 80.7 104.6 102.4 74.0 43.8 102.7 64.9 45.8 48.2 105.3 68.8 76.0 80.3 81.6 66.5 72.0 86.0 73.9 90.8 88.9 97.3 116.0 73.4 57.3 60.3 127.1 108.1 80.1 99.8 103.4 75.7 42.6 78.4 124.2 125.7 38.3 50.5 151.5 54.9 42.4 53.2 57.0 61.1 92.6 41.6 119.6 76.7 83.6 77.2 35.9 57.6 80.6 34.4 143.6 31.3 58.4 65.2 85.9 62.1 34.8 77.0 57.0 42.1 65.5 75.8 57.7 72.3 46.4 68.4 55.1 107.0 41.0 50.7 99.1 26.2 82.6 74.0 50.8 54.0 38.2 53.5 63.4 72.3 62.8 19.5 44.4 71.8 52.0 53.8 33.7 85.5 115.5 67.1 60.8 88.6 86.0 50.4 102.2 92.6 65.5 74.7 76.7 52.5 99.7 106.8 49.1 125.7 41.6 42.6 41.4 47.6 78.4 37.5 32.2 40.1 124.2 38.3 120.4 58.7 50.5 151.5 63.0 60.6 34.3 77.3 57.6 54.8 74.0 43.8 68.8 60.3 RNF213 "C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavourable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 17.0 15.1 7.4 16.9 10.3 22.4 10.2 4.7 7.5 11.0 12.2 15.6 14.9 8.5 16.6 13.0 13.2 9.7 12.1 8.5 7.8 7.8 17.1 11.6 15.4 17.9 10.9 5.6 11.5 9.0 41.1 11.4 15.1 10.0 11.2 8.0 12.3 11.7 12.5 9.0 8.7 14.8 13.6 14.3 17.0 10.6 5.9 8.7 24.5 15.9 7.5 18.2 13.6 15.4 7.2 13.9 37.9 9.6 11.4 12.1 1.8 16.1 28.7 2.9 2.0 10.5 16.1 2.2 4.1 8.9 18.5 15.8 3.0 7.5 1.0 3.5 8.5 9.4 3.9 5.3 6.3 36.5 1.7 2.5 11.6 5.3 4.5 2.6 2.6 8.8 3.6 10.4 4.5 14.2 4.6 6.0 6.9 3.9 10.5 1.1 2.1 6.6 7.2 6.7 1.2 5.1 14.0 2.8 3.9 9.9 21.1 7.5 4.8 3.3 18.3 10.3 8.2 6.0 4.2 2.6 2.4 2.9 7.7 3.1 3.7 6.9 9.6 4.2 12.1 8.0 8.1 6.2 8.6 9.7 2.3 7.2 6.9 8.5 37.9 11.4 6.9 13.9 6.4 1.8 7.4 10.3 4.7 7.5 7.8 7.8 10.9 5.6 10.0 8.7 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58352500-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 14.9;Hep G2: 29.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.7" "Region enriched" "Detected in many" 7 "cerebellum: 30.6" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008079 Uncertain "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favourable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.4 9.4 2.2 6.2 3.5 1.9 4.5 30.6 4.3 3.4 26.4 0.9 21.3 18.5 1.7 9.1 10.0 3.9 8.1 3.3 1.9 1.3 8.0 7.0 6.1 2.7 0.8 1.1 1.6 13.2 3.0 13.3 8.7 4.1 8.0 16.3 3.8 13.7 19.0 0.5 8.9 29.0 0.9 0.8 0.9 4.9 3.1 0.7 3.0 1.8 5.7 6.6 4.0 4.4 0.9 1.1 1.7 1.8 5.6 3.6 1.2 0.7 10.4 1.9 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 14.9 5.0 4.2 5.3 0.0 2.9 0.4 4.0 0.0 8.8 7.3 3.4 0.5 29.2 0.0 4.2 3.0 0.0 8.2 0.0 1.3 0.0 0.3 3.6 0.0 0.1 2.2 3.9 0.3 0.7 6.9 0.0 2.2 3.7 5.6 1.2 0.3 0.9 0.4 0.3 1.3 1.2 0.0 0.1 1.2 0.0 0.0 3.8 1.7 3.3 0.4 0.4 2.4 1.7 0.2 1.6 3.1 0.8 3.2 0.9 2.5 3.6 0.4 0.9 2.3 3.0 0.8 5.6 1.8 1.1 1.2 1.2 2.2 3.5 30.6 4.3 1.9 1.3 0.8 1.1 4.1 0.7 RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327564 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 55.4" "Cell line enhanced" "Detected in many" "HL-60: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 15.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.3" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: " "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" 16.4 5.9 6.1 7.1 9.0 17.4 13.8 7.2 7.0 8.3 8.4 7.1 2.5 5.1 8.8 9.4 5.4 20.8 9.4 6.3 7.2 9.4 4.9 4.9 10.7 7.8 8.9 4.2 7.9 7.2 3.8 55.4 6.3 14.6 5.9 6.4 6.3 3.7 4.8 13.3 4.3 6.2 8.3 9.9 5.1 4.9 11.6 5.7 5.8 8.3 3.6 5.4 7.7 10.9 1.9 2.6 15.3 2.6 1.6 3.1 1.7 3.3 4.4 2.5 2.3 2.9 4.1 1.9 4.2 4.9 3.1 3.6 1.9 1.7 4.9 1.4 2.7 3.2 3.0 1.3 4.3 5.2 5.5 1.8 2.1 3.9 2.6 22.5 4.3 5.9 1.8 6.2 7.0 14.1 2.3 0.0 4.2 1.3 6.6 12.6 6.5 5.6 4.9 8.6 4.6 2.7 2.2 1.9 3.7 4.6 1.9 5.0 1.2 3.9 16.4 3.4 6.0 8.0 5.0 1.4 2.7 4.3 8.0 4.4 4.6 1.4 2.6 5.7 1.4 2.3 3.1 1.9 1.7 1.8 2.6 1.8 2.5 2.0 15.3 1.6 1.8 1.8 1.9 1.7 6.1 9.0 7.2 7.0 7.2 9.4 8.9 4.2 14.6 5.7 RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6181269-6209389 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068294 Approved Nucleoplasm,Nucleoli 320000 Nucleoli Nucleoplasm "HPA068294: " "unprognostic (3.16e-3)" "unprognostic (1.28e-1)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-3)" "unprognostic (4.40e-2)" "unprognostic (7.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.48e-1)" "unprognostic (4.24e-2)" "unprognostic (1.46e-3)" "unprognostic (3.83e-1)" "unprognostic (3.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.98e-1)" 75.5 71.5 54.3 79.7 42.8 124.7 75.0 46.7 39.5 95.8 73.9 39.2 53.9 66.5 133.6 63.9 103.9 59.1 61.8 50.8 47.4 38.6 58.8 90.2 55.3 142.6 50.6 39.7 163.1 154.8 30.4 57.0 49.8 37.4 90.8 46.4 57.0 140.3 66.8 114.0 79.7 62.6 106.6 58.3 79.1 62.0 38.2 35.0 95.3 91.0 112.8 81.1 101.5 91.9 75.6 62.3 11.0 38.9 42.2 98.8 73.9 88.0 25.1 53.5 54.6 37.7 59.3 42.3 76.9 30.9 28.3 24.2 49.8 76.6 136.7 63.3 28.5 50.9 40.2 40.0 37.3 66.9 65.4 132.8 57.2 61.7 37.4 175.7 53.3 52.3 33.1 25.2 52.2 35.3 109.4 82.8 32.5 38.8 76.8 143.4 33.3 55.7 74.1 111.0 105.8 41.4 30.6 74.0 67.9 62.6 181.4 140.8 58.4 139.3 86.3 40.4 44.5 53.3 72.2 66.7 91.4 206.8 26.7 181.7 25.0 11.0 38.9 8.8 38.0 34.3 66.9 75.6 71.1 52.3 59.8 72.4 98.8 78.1 2.9 42.2 27.8 62.3 54.0 73.9 54.3 42.8 46.7 39.5 47.4 38.6 50.6 39.7 37.4 35.0 RPL5 "L5, PPP1R135" ENSG00000122406 "Ribosomal protein L5" P46777 1 92831983-92841924 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA043717, HPA054444" Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" 130000 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA043717: AB_10964719, HPA054444: " "unprognostic (5.81e-3)" "unprognostic (3.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (9.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.03e-3)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.98e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (6.81e-5)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-1)" 119.4 80.3 50.0 70.0 50.1 113.8 140.5 46.9 46.8 158.6 111.4 45.0 75.1 61.7 135.2 114.6 159.4 100.5 73.1 73.0 43.5 43.1 99.7 114.9 89.9 148.2 54.5 36.2 296.8 306.5 40.8 90.3 90.2 44.3 175.4 78.8 64.3 121.5 73.2 109.1 97.8 95.3 153.4 61.9 130.1 90.0 68.8 45.7 156.6 210.0 97.7 118.9 191.2 146.6 104.5 85.2 12.8 45.9 72.4 143.0 142.1 116.8 50.2 89.5 75.5 116.4 235.3 143.6 69.9 93.6 87.1 62.4 133.0 51.1 220.5 112.3 78.5 74.7 102.6 131.0 111.3 69.8 140.4 114.4 83.6 122.4 139.7 175.1 48.2 192.4 206.7 77.3 170.2 120.2 141.6 116.3 99.7 66.3 139.4 198.6 138.2 94.9 128.1 173.4 142.4 105.6 97.3 76.3 91.3 45.5 127.1 203.3 70.0 240.9 73.0 44.0 80.4 83.1 126.0 72.0 68.3 149.2 29.8 151.0 29.8 12.8 45.9 7.2 60.9 44.8 122.1 104.5 111.5 91.6 85.2 88.4 143.0 123.9 4.4 72.4 38.3 71.1 83.2 142.1 50.0 50.1 46.9 46.8 43.5 43.1 54.5 36.2 44.3 45.7 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "Runt related transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 54.3;lymphoid tissue: 58.6" "Cell line enhanced" "Detected in many" "HEL: 65.0;HMC-1: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 17.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: " "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavourable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 11.5 3.2 5.2 14.8 7.3 29.8 54.3 1.0 4.3 12.5 4.7 3.8 4.0 3.8 2.9 7.4 6.5 4.6 12.4 7.6 6.1 2.0 4.2 6.7 17.9 13.9 8.5 1.1 6.5 5.8 1.6 5.5 6.4 6.0 9.9 5.1 3.5 29.8 8.8 14.4 8.3 5.1 6.8 12.3 10.6 12.7 2.9 6.6 58.6 4.6 5.7 14.2 11.0 9.1 3.2 3.4 17.0 3.9 1.3 4.8 2.0 13.0 1.0 0.0 0.1 3.4 4.4 8.6 7.4 7.5 4.1 3.1 0.6 10.0 6.4 0.5 6.5 11.8 0.8 8.8 6.0 9.9 1.0 65.0 2.6 3.0 6.3 7.5 39.2 8.5 5.3 12.5 12.4 2.3 4.4 3.8 8.7 2.8 30.3 11.9 0.6 3.8 30.7 22.8 3.9 5.5 5.2 0.3 0.0 7.6 1.9 2.7 3.9 17.6 9.7 6.8 8.8 10.1 11.1 12.5 5.1 6.1 8.5 16.5 9.9 17.0 3.2 6.3 3.4 1.4 3.3 3.2 3.1 3.2 0.9 3.1 4.8 3.8 3.5 1.3 3.9 3.4 4.0 2.0 5.2 7.3 1.0 4.3 6.1 2.0 8.5 1.1 6.0 6.6 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.9;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 14.9;monocytes: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favourable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavourable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 18.5 10.1 9.9 10.4 6.7 19.6 36.8 4.6 9.8 11.0 9.3 4.9 8.1 14.0 10.1 6.1 24.2 9.3 12.9 14.2 9.0 3.7 11.7 49.3 12.8 10.4 6.0 7.0 11.7 20.6 8.0 10.7 9.6 9.4 9.7 2.0 9.5 9.3 9.7 45.8 19.0 15.2 10.6 9.5 11.5 8.8 5.9 8.1 1.5 13.6 18.3 5.9 16.0 23.7 0.1 1.7 14.9 12.3 1.3 1.1 1.8 5.5 15.6 2.0 5.0 3.5 3.3 24.0 3.0 3.5 4.3 2.5 8.6 8.7 0.0 8.2 4.3 27.0 0.7 10.6 0.2 7.9 2.0 0.0 19.0 13.1 4.5 6.5 2.4 5.3 4.5 5.4 2.5 3.7 10.7 0.5 1.0 14.9 0.5 1.4 3.8 5.4 2.8 7.4 10.8 0.2 24.1 4.4 2.0 9.5 9.1 2.4 12.6 8.9 4.8 5.3 6.4 5.7 2.6 0.7 0.0 0.1 4.0 6.6 3.4 1.1 5.2 2.8 1.1 9.3 0.0 0.1 0.7 0.7 1.7 0.0 0.2 0.9 14.9 1.3 12.3 0.1 0.9 1.8 9.9 6.7 4.6 9.8 9.0 3.7 6.0 7.0 9.4 8.1 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2" Q9BYW2 3 47016429-47163967 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavourable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favourable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 13.2 10.5 12.2 15.2 15.4 20.0 11.7 22.4 16.4 13.4 14.0 9.1 12.9 9.5 15.8 7.5 10.8 11.4 8.7 8.8 10.6 6.8 11.4 10.3 10.4 11.8 11.7 9.5 16.0 13.4 21.4 16.3 10.7 11.3 12.4 10.9 7.7 12.7 14.8 27.6 12.5 11.5 11.9 9.8 13.8 10.4 12.8 12.8 23.2 15.8 5.5 12.8 16.1 15.5 4.8 2.6 6.0 2.3 7.1 3.9 1.0 11.4 9.0 15.2 7.8 9.1 10.6 6.4 10.6 10.3 12.4 11.3 9.5 7.5 25.3 6.6 14.5 7.0 16.4 10.1 16.8 14.5 6.5 25.9 15.1 7.3 6.8 19.4 15.0 9.1 9.7 12.2 15.2 11.4 16.6 9.6 10.1 6.0 14.2 2.6 11.5 7.5 9.4 14.7 13.1 6.2 15.1 6.6 10.5 17.8 7.0 6.6 7.4 14.4 14.6 13.6 10.2 11.6 16.8 12.2 13.6 25.5 7.9 11.1 7.9 2.4 2.2 5.2 3.9 2.3 2.4 3.7 2.4 3.0 2.5 4.8 3.5 3.0 6.0 7.1 1.9 2.6 1.0 1.0 12.2 15.4 22.4 16.4 10.6 6.8 11.7 9.5 11.3 12.8 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197389784-197435091 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" 840000 "Nuclear speckles" "HPA050275: " "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 53.9 49.9 36.5 54.5 44.9 88.0 57.9 60.8 47.3 72.3 54.2 44.3 45.6 36.8 64.6 72.0 50.5 53.3 43.1 39.6 34.7 26.0 49.7 50.7 53.1 65.3 56.5 27.7 73.6 60.5 66.2 81.4 64.6 46.7 50.0 51.0 37.0 54.4 45.4 49.3 48.5 67.8 41.2 50.2 88.1 48.8 33.3 53.5 113.0 53.3 38.0 65.7 62.4 56.0 32.7 41.9 41.1 37.8 39.6 45.9 29.4 30.7 28.2 63.6 34.7 49.3 50.4 53.4 43.0 44.0 37.6 46.1 53.8 33.2 58.7 29.0 43.7 29.8 63.5 34.9 58.8 44.9 39.5 62.1 69.0 63.2 37.2 65.9 45.3 52.6 34.1 39.1 48.2 43.7 44.4 40.5 41.6 27.0 60.6 63.5 50.0 44.6 53.4 54.4 39.0 52.2 78.2 35.7 44.3 41.1 25.2 29.4 24.9 50.5 44.0 29.5 25.4 29.8 30.5 37.0 60.1 84.3 28.3 39.9 32.6 27.7 33.1 39.1 37.5 37.8 40.6 32.7 32.5 35.3 41.9 30.8 33.9 33.9 41.1 39.6 36.1 23.8 45.9 29.4 36.5 44.9 60.8 47.3 34.7 26.0 56.5 27.7 46.7 53.5 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell line enhanced" "Detected in many" "HHSteC: 50.1;RPTEC TERT1: 76.9;SK-MEL-30: 49.8;TIME: 59.8;U-266/84: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: " "unprognostic (2.05e-2)" "prognostic favourable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.6 2.1 0.9 12.3 25.7 16.1 13.2 1.9 1.7 2.0 1.8 12.7 0.4 1.1 1.9 11.9 0.0 0.5 0.1 30.7 1.4 50.1 0.1 1.1 12.9 12.4 15.8 20.6 27.0 3.9 31.4 5.7 0.1 0.1 0.4 0.7 1.3 0.3 1.4 0.2 76.9 0.2 0.3 3.0 38.7 0.1 49.8 0.0 0.3 59.8 4.7 2.0 28.9 2.7 5.9 54.8 6.3 4.4 1.9 6.3 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB004506: AB_2187766, HPA047213: AB_2679984, HPA062123: AB_2684689" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (3.52e-1)" 21.0 15.4 14.0 19.4 18.5 31.6 20.4 26.3 15.5 26.3 20.2 19.9 15.3 11.8 26.6 16.8 17.7 22.1 15.9 13.4 14.2 11.8 13.6 13.9 17.4 20.7 13.0 14.2 27.6 19.8 23.4 16.8 17.2 13.0 22.9 14.3 23.0 17.6 20.5 18.2 23.5 17.9 24.5 12.8 20.3 16.8 28.5 15.1 48.7 24.0 12.8 26.9 26.0 19.0 9.8 6.5 9.3 8.3 9.7 12.7 6.3 12.7 26.4 23.6 15.5 11.8 12.5 13.7 9.6 14.9 14.1 15.2 14.6 17.3 27.8 10.0 14.1 22.8 34.2 14.4 15.5 22.4 17.7 26.2 20.1 11.4 8.9 24.8 22.4 15.1 11.1 16.4 17.2 12.6 20.6 31.0 11.4 14.8 24.3 15.9 23.0 11.1 24.6 31.3 17.1 10.1 23.4 18.7 18.7 23.6 10.6 13.2 16.1 19.7 11.0 17.5 23.7 11.5 14.1 21.3 33.4 29.5 10.4 25.4 9.7 3.3 4.8 6.9 8.5 4.8 12.7 9.3 10.8 10.7 6.5 9.8 11.1 9.5 9.3 9.7 8.3 4.4 9.5 6.3 14.0 18.5 26.3 15.5 14.2 11.8 13.0 14.2 13.0 15.1 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: " "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 38.5 39.2 29.0 26.2 25.9 19.6 31.4 19.5 28.9 28.8 34.2 29.4 28.9 21.5 26.6 26.3 33.5 28.8 25.7 31.1 26.1 27.1 26.4 20.9 28.3 23.8 30.9 24.3 36.6 28.1 25.7 24.4 34.8 28.6 27.8 29.8 31.7 29.7 28.7 33.9 28.0 26.4 34.6 35.4 34.1 26.3 29.2 26.2 60.7 46.1 23.6 31.5 35.1 35.7 12.0 21.8 28.9 24.7 24.5 25.9 19.7 22.4 32.2 19.7 19.0 31.5 38.5 22.5 24.5 29.4 25.6 29.9 12.3 21.5 34.9 17.6 31.0 24.8 22.1 27.3 34.3 37.9 11.3 29.6 48.7 19.9 36.7 41.1 30.3 28.4 35.3 21.9 50.7 28.2 13.7 29.3 31.4 14.6 28.2 19.8 9.6 7.7 20.6 28.7 23.8 57.4 38.7 18.2 21.4 29.5 20.2 24.0 15.3 27.4 31.5 38.0 21.9 10.3 17.8 28.7 27.5 30.4 26.3 28.1 27.7 28.9 22.6 25.0 16.9 24.7 21.2 12.0 23.1 20.9 21.8 9.4 25.8 19.8 22.7 24.5 20.8 15.5 25.9 19.7 29.0 25.9 19.5 28.9 26.1 27.1 30.9 24.3 28.6 26.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favourable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 25.6 17.5 16.0 14.0 16.7 11.4 24.9 29.7 16.0 27.9 22.6 17.9 21.3 15.1 28.2 18.8 21.7 20.5 17.5 19.6 15.3 11.5 21.0 22.0 20.1 16.0 17.2 13.3 30.5 25.0 30.0 28.9 30.6 14.2 27.8 17.4 18.4 23.1 22.8 39.7 18.2 23.4 27.6 13.9 21.7 19.3 17.6 18.4 38.8 35.0 13.9 18.1 29.0 24.1 3.6 3.6 3.4 1.8 2.9 4.7 1.3 8.5 11.3 30.7 8.8 12.7 19.6 17.3 15.0 16.5 20.2 25.4 6.9 2.0 14.2 4.5 13.0 14.1 17.2 6.7 21.5 12.3 9.7 9.8 11.3 7.9 12.6 17.1 7.7 8.9 11.4 9.9 14.6 14.6 11.0 13.1 11.9 4.5 10.1 4.9 16.0 7.1 13.2 15.6 13.9 9.7 3.7 19.0 11.3 14.0 2.6 9.3 7.0 10.0 11.0 17.1 7.9 4.3 9.9 19.7 13.7 12.3 11.1 6.7 11.3 0.8 1.8 1.8 3.2 1.1 3.7 2.2 3.3 2.6 3.6 3.6 4.0 4.7 3.4 2.9 1.3 2.9 4.3 1.3 16.0 16.7 29.7 16.0 15.3 11.5 17.2 13.3 14.2 18.4 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960825-11079426 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004208 Supported Supported Nucleoplasm 260000 Nucleoplasm "CAB004208: AB_626762" "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavourable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 10.3 12.4 15.5 18.0 21.3 20.5 10.9 29.1 28.0 13.2 12.8 16.6 9.7 14.3 16.6 9.4 24.7 15.7 12.8 11.6 14.4 17.7 13.0 9.9 13.0 18.1 17.1 16.8 13.6 13.4 18.1 11.5 14.6 16.1 13.3 9.4 17.3 18.2 12.5 21.9 20.4 12.0 10.6 16.1 13.2 14.5 22.2 12.4 58.2 15.5 10.1 21.5 15.2 12.6 9.8 11.2 8.6 13.5 11.4 13.7 5.9 20.5 1.1 36.7 34.7 7.2 6.1 16.1 14.3 8.6 17.5 13.0 28.7 0.9 48.3 22.2 12.5 15.1 28.6 17.7 9.7 19.8 21.5 38.5 18.2 33.3 10.9 27.9 19.2 10.3 8.6 14.7 15.2 15.6 34.4 18.2 13.7 42.0 46.2 23.9 37.3 31.1 49.3 23.2 25.0 11.2 26.1 41.8 37.9 15.2 19.6 16.3 16.6 20.9 20.7 26.1 13.6 23.8 23.6 37.7 41.8 48.0 14.8 26.8 22.2 8.1 8.3 8.6 13.7 9.5 12.2 7.4 10.4 11.6 8.5 9.8 11.4 11.2 5.2 11.4 13.5 11.2 8.8 5.9 15.5 21.3 29.1 28.0 14.4 17.7 17.1 16.8 16.1 12.4 SMC1A "DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb" ENSG00000072501 "Structural maintenance of chromosomes 1A" Q14683 X 53374149-53422728 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005499, CAB025404" Supported Enhanced Nucleoplasm Nucleoplasm "CAB025404: , HPA005499: AB_1080028" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.04e-1)" "unprognostic (9.89e-2)" "unprognostic (1.29e-3)" "unprognostic (1.89e-1)" "unprognostic (9.80e-3)" "unprognostic (9.49e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-2)" "unprognostic (2.58e-1)" "unprognostic (4.18e-3)" "unprognostic (6.28e-2)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" 20.6 14.1 14.6 24.2 28.2 24.6 16.2 33.6 21.7 19.9 18.2 22.0 10.5 16.2 27.5 10.0 22.4 21.7 12.5 16.2 16.8 10.8 19.2 23.5 15.4 30.2 25.2 13.0 21.8 17.2 31.0 18.4 19.5 18.0 13.4 17.3 12.5 16.8 12.9 24.3 16.2 19.7 21.7 21.3 20.1 17.5 10.4 25.8 38.3 16.8 11.1 25.7 22.0 21.3 14.3 15.5 13.7 18.7 15.6 17.8 10.6 28.2 31.7 25.2 21.5 9.3 10.3 14.1 17.1 11.3 21.7 17.6 18.8 16.5 27.6 14.7 11.4 21.6 44.9 24.7 24.3 23.6 52.3 24.1 36.8 13.1 3.8 34.0 34.6 5.8 6.4 24.3 14.8 18.7 35.4 17.8 16.9 17.1 30.6 10.3 37.4 16.9 32.9 43.5 25.5 9.2 18.6 26.8 22.6 44.7 22.1 9.4 23.7 13.9 10.5 18.5 19.6 18.3 16.6 11.7 19.7 25.6 10.6 38.7 18.1 6.1 13.8 13.7 17.8 18.7 17.0 12.2 12.0 15.6 15.5 14.3 14.2 10.9 9.4 15.6 17.4 12.9 8.8 10.6 14.6 28.2 33.6 21.7 16.8 10.8 25.2 13.0 18.0 25.8 SMC3 "BAM, bamacan, CSPG6, HCAP, SMC3L1" ENSG00000108055 "Structural maintenance of chromosomes 3" Q9UQE7 10 110567691-110604636 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037411, HPA043206" Uncertain Supported Nucleoplasm 10000000 Nucleoplasm "HPA037411: AB_10671753, HPA043206: " "unprognostic (3.40e-1)" "unprognostic (1.73e-2)" "unprognostic (9.05e-2)" "unprognostic (3.00e-2)" "unprognostic (3.73e-2)" "unprognostic (8.89e-3)" "unprognostic (9.74e-3)" "unprognostic (8.06e-2)" "unprognostic (5.31e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (1.17e-2)" "unprognostic (8.73e-3)" "unprognostic (7.22e-2)" "unprognostic (5.18e-2)" "unprognostic (7.95e-2)" "unprognostic (1.32e-1)" 17.1 13.4 16.8 15.4 22.9 32.7 21.3 37.8 18.0 19.2 15.1 9.9 10.7 13.3 20.1 14.3 19.7 15.6 9.9 11.9 16.7 11.2 16.6 17.2 12.6 23.7 18.6 15.4 26.5 18.4 22.2 36.6 22.9 17.7 14.6 15.1 8.8 15.3 14.3 18.4 18.4 18.8 19.6 22.2 18.1 13.5 32.0 23.2 47.4 19.4 11.4 20.8 20.7 19.7 13.2 11.0 19.1 10.5 15.1 17.7 7.4 26.8 16.8 36.6 26.0 12.2 10.5 15.8 21.8 21.8 20.2 19.9 21.2 22.7 35.1 9.6 14.6 21.5 26.2 13.2 30.9 28.6 22.5 28.3 21.2 19.0 12.2 40.2 21.9 8.3 10.8 22.3 35.2 14.8 22.5 27.2 17.4 14.1 30.9 21.4 25.2 13.5 26.3 66.3 19.0 12.5 12.0 20.9 23.9 23.5 6.8 17.9 10.9 19.7 15.2 16.3 25.8 18.3 31.4 15.8 14.1 38.0 14.5 38.8 13.3 19.1 7.7 18.6 13.0 10.5 16.1 13.2 15.1 14.0 8.4 13.1 15.5 15.1 8.4 15.1 8.9 11.0 17.7 7.4 16.8 22.9 37.8 18.0 16.7 11.2 18.6 15.4 17.7 23.2 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981396-39124345 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 25.9 13.2 19.2 18.8 18.1 12.0 26.1 33.3 18.6 18.6 21.9 12.1 15.3 18.3 19.1 14.6 17.4 17.0 18.1 16.4 17.9 14.1 14.6 15.2 19.9 19.9 18.2 14.0 28.1 13.0 33.5 21.7 21.5 17.8 18.4 16.8 14.6 15.9 18.1 26.2 15.0 23.1 22.3 14.6 16.2 20.1 12.7 20.1 23.1 19.4 12.9 21.8 25.1 22.0 3.2 1.4 3.2 2.0 6.2 4.6 0.9 9.7 6.0 9.4 6.7 12.7 15.2 9.8 6.2 7.6 4.9 4.7 6.5 5.9 14.2 4.2 8.0 5.8 11.0 5.6 9.2 14.2 4.9 22.0 5.2 8.9 5.2 7.0 55.8 9.3 9.0 6.7 6.5 7.7 9.3 6.7 6.3 5.3 7.5 6.5 5.8 4.3 8.4 8.5 4.1 5.2 7.9 9.1 9.1 7.3 13.2 7.6 4.2 3.7 8.6 8.2 6.7 6.4 6.1 7.9 8.0 7.5 6.6 6.9 4.9 0.0 1.2 3.2 3.2 1.8 4.6 3.2 3.3 3.3 1.0 2.4 3.7 3.4 1.4 6.2 2.0 1.4 1.9 0.9 19.2 18.1 33.3 18.6 17.9 14.1 18.2 14.0 17.8 20.1 SOX17 ENSG00000164736 "SRY-box 17" Q9H6I2 8 54457935-54460888 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "EFO-21: 49.1" "Group enriched" "Detected in many" 12 "endometrial cancer: 122.8;ovarian cancer: 96.2;testis cancer: 25.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm Nucleoplasm "CAB025594: , HPA068399: " "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favourable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 26.7 2.0 1.2 9.1 1.8 0.6 31.3 0.6 2.9 25.7 7.9 1.5 1.0 1.4 23.9 7.1 11.6 23.1 20.2 20.6 1.5 1.3 3.0 2.2 8.7 1.5 2.0 1.0 13.0 1.5 1.7 1.5 9.9 2.3 7.6 1.6 3.6 2.4 3.0 13.3 3.1 3.3 5.9 1.8 15.7 3.7 5.8 0.4 0.8 3.6 6.2 1.3 12.3 5.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.1 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.6 2.9 1.5 1.3 2.0 1.0 2.3 0.4 SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295372-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 61.8" "Cell line enhanced" "Detected in many" "AN3-CA: 10.4;ASC TERT1: 17.6;HSkMC: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 8.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: " "unprognostic (1.36e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (2.87e-2)" "unprognostic (3.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.77e-2)" "unprognostic (4.69e-3)" "unprognostic (2.40e-2)" "unprognostic (2.61e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (3.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (7.89e-2)" "unprognostic (5.71e-3)" 5.8 8.9 6.2 3.0 12.9 1.5 8.4 2.4 8.9 7.5 5.0 12.9 10.1 3.3 6.9 7.9 4.1 16.2 5.9 4.7 7.8 5.6 6.9 2.4 7.5 7.0 14.9 3.9 9.0 5.2 12.8 21.5 5.3 8.5 6.4 4.6 6.6 6.9 12.2 3.8 5.0 3.7 8.3 10.0 4.1 7.3 61.8 13.4 1.1 10.3 2.4 2.2 6.5 12.2 0.2 1.7 5.2 8.2 0.3 0.6 0.7 0.1 0.9 9.4 10.4 8.8 17.6 1.3 1.0 3.9 0.8 0.7 0.1 0.7 0.0 0.6 1.7 0.2 0.8 2.3 0.7 0.7 1.3 0.1 0.4 0.4 1.8 0.0 0.7 12.5 1.8 1.5 0.5 3.7 0.1 0.0 3.9 0.3 0.1 0.1 4.0 1.0 2.9 0.0 0.9 5.8 1.6 2.3 5.2 3.8 0.4 9.0 2.3 0.5 1.1 1.4 1.4 2.2 1.5 0.0 0.0 0.0 5.8 0.1 6.2 0.0 1.8 5.2 0.1 4.3 0.0 0.2 0.4 0.0 1.7 0.1 0.6 0.5 0.3 0.3 8.2 0.8 0.0 0.7 6.2 12.9 2.4 8.9 7.8 5.6 14.9 3.9 8.5 13.4 SPEN "KIAA0929, MINT, RBM15C, SHARP" ENSG00000065526 "Spen family transcriptional repressor" Q96T58 1 15847864-15940460 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015825, HPA050257" Supported Enhanced Nucleoplasm Nucleoplasm "HPA015825: AB_1856823, HPA050257: " "unprognostic (3.91e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.06e-2)" "unprognostic (6.93e-3)" "unprognostic (2.26e-1)" "unprognostic (4.26e-2)" "unprognostic (4.88e-3)" "unprognostic (1.71e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (1.83e-1)" 18.2 11.2 18.2 18.2 22.2 27.2 17.3 38.2 25.9 18.5 13.4 20.7 17.7 11.9 19.0 12.7 16.7 19.4 11.8 13.5 17.6 11.5 14.4 13.2 17.8 16.6 23.4 17.5 31.2 23.9 35.1 17.5 16.2 19.0 14.9 13.3 11.6 16.2 16.2 24.0 22.8 16.0 15.1 22.0 16.5 13.7 13.6 23.3 18.3 20.1 8.7 18.0 17.1 41.9 5.0 2.7 7.7 2.4 1.3 1.7 0.6 12.5 10.7 13.4 10.0 13.4 8.2 7.2 6.5 8.6 7.1 6.0 9.6 9.8 17.8 7.8 12.8 18.2 12.5 11.6 11.5 15.9 34.7 22.3 9.4 6.1 6.1 18.3 10.7 6.0 8.4 10.6 15.4 8.0 23.1 18.3 5.7 7.0 15.1 7.2 6.0 8.2 14.6 13.0 11.0 4.0 11.3 10.3 10.4 18.3 9.0 7.8 3.2 9.0 14.5 6.5 8.1 12.6 9.3 11.1 7.2 20.3 6.4 14.7 9.1 7.7 1.5 0.9 1.6 2.4 1.3 1.8 1.7 1.4 0.7 5.0 0.9 1.3 4.2 1.3 1.2 2.7 1.1 0.6 18.2 22.2 38.2 25.9 17.6 11.5 23.4 17.5 19.0 23.3 SPOP "BTBD32, TEF2" ENSG00000121067 "Speckle type BTB/POZ protein" O43791 17 49598884-49678234 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (8.83e-2)" "unprognostic (3.23e-1)" "unprognostic (2.15e-2)" "unprognostic (4.51e-2)" "prognostic unfavourable (6.88e-4)" "unprognostic (1.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.24e-3)" "unprognostic (7.67e-2)" "unprognostic (2.81e-1)" "unprognostic (3.45e-2)" "unprognostic (1.10e-2)" "unprognostic (3.29e-1)" 22.0 16.5 22.5 16.9 24.9 7.9 18.6 39.8 26.9 27.5 59.5 25.0 25.1 15.2 36.2 21.2 35.4 25.2 17.2 22.7 22.7 18.8 17.0 20.2 19.1 19.6 20.9 21.4 26.0 18.5 15.1 28.5 18.2 23.2 38.8 23.5 21.8 22.8 49.5 29.2 15.2 24.1 45.1 18.4 18.8 28.4 10.5 26.8 28.6 26.4 14.3 23.3 35.6 22.3 43.2 55.6 59.6 43.1 40.7 58.4 50.8 14.2 16.1 18.6 7.0 20.9 22.3 12.6 18.7 19.4 24.8 25.8 32.7 15.7 23.6 35.9 17.0 11.5 21.0 13.6 29.7 43.6 23.3 27.3 16.4 18.6 24.0 17.9 22.3 16.7 17.5 19.4 21.1 25.3 28.2 24.3 16.7 13.9 32.9 16.5 4.9 19.6 18.7 27.0 30.4 13.4 8.5 27.9 13.0 11.8 6.0 15.4 23.1 18.7 22.1 26.9 18.7 21.1 15.4 24.3 20.3 20.6 15.8 16.1 13.5 57.0 41.8 50.6 36.2 37.1 36.1 42.4 40.6 39.2 55.6 43.2 58.4 45.3 59.6 40.7 43.1 37.2 36.0 50.8 22.5 24.9 39.8 26.9 22.7 18.8 20.9 21.4 23.2 26.8 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 24.0 18.8 21.5 23.9 23.7 39.7 30.1 35.4 23.5 28.1 25.1 16.4 25.2 14.9 24.3 21.0 24.3 20.0 16.3 15.7 21.4 17.9 22.2 18.1 23.4 26.2 24.9 17.5 31.1 19.7 46.1 27.6 25.5 20.6 25.9 18.3 14.2 20.7 27.8 27.6 18.9 21.9 25.9 30.6 26.7 17.6 9.3 26.4 69.3 32.0 19.7 27.1 37.7 37.8 12.8 12.5 30.3 14.4 12.1 15.5 6.7 17.2 16.3 24.5 15.4 10.5 15.9 15.8 16.4 17.7 17.0 21.5 15.1 18.5 31.9 23.2 14.7 15.8 50.1 13.9 24.2 22.6 21.4 29.5 32.6 9.9 10.9 38.5 23.2 12.5 13.8 20.1 32.6 14.2 28.7 34.0 12.5 18.8 49.2 17.4 12.8 24.2 34.9 32.4 26.6 13.2 33.0 22.1 17.7 37.0 13.8 19.4 8.2 17.7 17.3 0.1 9.1 20.0 18.6 14.7 22.1 40.1 10.7 23.7 17.1 16.8 10.2 18.1 10.8 13.1 12.6 10.0 11.2 10.1 12.5 12.8 15.5 12.4 30.3 12.1 14.4 11.2 8.7 6.7 21.5 23.7 35.4 23.5 21.4 17.9 24.9 17.5 20.6 26.4 STAT3 APRF ENSG00000168610 "Signal transducer and activator of transcription 3" P40763 17 42313324-42388568 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Diabetes mellitus, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001671, CAB003859, HPA058603, CAB068241, CAB068242" Supported Supported Nucleoplasm,Cytosol 220000 "Nucleoplasm, Cytosol" "CAB003859: AB_347629, CAB068241: , CAB068242: , HPA001671: AB_1080102, HPA058603: " "unprognostic (1.83e-2)" "unprognostic (2.42e-1)" "unprognostic (9.23e-3)" "unprognostic (2.91e-1)" "unprognostic (5.59e-3)" "unprognostic (1.78e-2)" "unprognostic (8.26e-2)" "unprognostic (1.51e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (6.47e-3)" "unprognostic (7.75e-3)" "unprognostic (2.21e-2)" "unprognostic (7.63e-2)" "unprognostic (1.61e-1)" 44.6 30.7 23.2 34.4 27.5 35.3 49.3 15.7 23.5 25.1 31.5 18.4 21.7 20.5 33.2 27.4 36.4 32.7 34.0 82.9 20.1 14.7 34.5 90.0 45.7 45.5 26.0 11.1 40.6 32.1 18.6 27.9 24.6 27.6 28.9 21.8 24.3 29.3 22.9 53.4 28.4 28.6 49.7 25.1 41.4 29.4 15.4 25.7 16.8 38.0 31.2 28.8 40.4 53.1 10.8 13.7 69.7 20.2 13.9 21.7 26.7 16.6 31.7 14.0 13.8 30.0 28.6 10.2 19.6 24.9 17.0 16.6 8.3 16.2 5.2 19.4 19.4 25.5 12.7 20.0 13.9 43.0 8.7 36.2 19.3 17.1 22.2 8.8 23.6 44.6 19.7 13.5 19.6 23.0 22.2 16.6 11.2 11.8 32.6 8.8 8.1 0.0 7.2 37.4 7.7 26.9 21.7 12.9 8.4 22.6 53.6 8.1 28.1 13.3 19.4 26.3 13.5 15.6 16.0 25.7 20.0 4.4 16.3 9.4 11.6 26.2 19.4 24.9 21.7 20.2 17.3 10.8 16.0 16.8 13.7 10.4 16.6 15.8 69.7 13.9 18.7 7.5 12.0 26.7 23.2 27.5 15.7 23.5 20.1 14.7 26.0 11.1 27.6 25.7 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: " "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favourable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favourable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.1 10.2 7.8 14.7 7.4 6.7 16.5 10.3 10.8 9.7 10.4 8.3 14.8 13.9 11.5 10.8 13.7 7.6 15.9 3.0 25.9 18.7 14.2 0.6 10.5 15.9 14.2 23.8 12.2 11.6 7.5 11.1 9.7 26.5 19.1 5.5 15.8 13.7 14.4 14.9 12.6 21.7 8.3 15.5 8.8 15.5 18.1 13.0 0.0 7.7 11.1 12.1 23.4 13.1 10.1 11.4 19.7 16.4 37.6 15.8 10.4 10.0 19.0 10.3 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937018-32001045 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli, Nuclear bodies" "HPA057436: " "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 10.1 10.8 13.4 15.4 10.4 25.5 33.5 16.0 13.8 11.2 11.4 7.5 13.6 10.1 12.5 8.1 12.3 9.8 7.7 9.7 9.1 7.6 10.9 11.5 10.6 19.9 9.3 9.9 10.0 10.1 15.5 10.4 15.3 9.5 10.7 10.9 6.9 10.1 9.6 8.7 9.9 12.2 9.6 7.7 15.2 10.7 17.1 12.5 31.8 12.0 6.5 18.9 10.8 19.5 5.5 4.6 4.1 2.6 4.4 5.5 1.2 14.0 12.5 11.8 13.5 6.8 8.8 12.1 13.7 12.1 16.9 20.5 9.4 7.9 30.8 10.6 8.5 12.5 17.5 7.9 27.5 10.8 17.0 21.3 10.6 6.8 8.0 33.5 21.9 6.1 8.9 16.8 12.9 10.3 20.5 42.8 14.5 4.9 39.8 19.5 6.7 7.6 23.8 30.2 24.9 9.9 13.8 15.1 11.8 22.1 7.2 13.2 20.8 28.0 7.6 13.4 12.2 16.1 21.1 23.4 29.1 38.1 9.8 20.7 12.1 1.4 1.9 3.8 3.8 2.6 3.0 5.5 4.1 4.0 1.4 4.4 3.9 5.5 4.1 4.4 1.8 4.6 4.2 1.2 13.4 10.4 16.0 13.8 9.1 7.6 9.3 9.9 9.5 12.5 SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease mutation, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 33.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 33.8" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" 12.7 11.5 18.2 9.1 30.2 41.7 9.0 62.0 25.0 16.8 7.3 9.8 12.4 2.7 15.2 18.4 6.2 12.9 7.9 22.7 21.0 17.5 18.4 11.2 16.1 13.7 13.2 15.1 27.7 10.6 37.3 37.0 4.7 19.7 10.1 6.3 10.5 3.6 12.5 22.0 16.9 5.3 19.1 9.7 15.5 9.0 8.3 11.6 9.0 20.6 9.5 12.1 10.0 12.3 3.2 0.8 33.8 1.5 4.7 6.4 1.4 0.1 3.9 2.8 3.2 3.9 8.6 1.0 8.8 4.6 2.3 4.2 0.8 0.1 8.3 0.5 4.8 0.2 1.0 2.3 2.4 10.0 2.7 3.5 2.6 2.7 9.0 0.6 1.6 5.5 0.5 5.0 10.3 4.4 0.0 9.5 6.2 0.4 1.4 0.1 0.6 1.5 1.9 5.5 2.3 8.9 0.1 1.7 2.6 1.4 0.5 6.1 0.5 0.3 5.9 10.7 14.5 3.7 4.8 18.9 8.0 13.3 5.9 1.9 3.1 3.0 1.1 33.8 6.4 0.7 4.1 2.9 4.2 6.1 0.8 3.2 4.0 5.1 1.1 4.7 1.5 0.7 5.1 1.4 18.2 30.2 62.0 25.0 21.0 17.5 13.2 15.1 19.7 11.6 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366239-71532374 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001075, CAB016283" Supported Enhanced Nucleoplasm Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favourable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 20.1 16.2 15.0 17.1 19.8 16.3 17.7 20.7 18.0 20.7 15.5 23.8 17.1 10.0 25.4 17.1 14.4 19.1 16.1 12.9 15.4 12.0 11.9 12.9 13.8 17.8 18.5 16.5 23.9 17.5 25.5 19.3 15.4 17.3 16.9 15.4 20.8 14.5 16.1 19.6 16.8 17.1 18.3 17.2 21.3 15.8 12.2 21.3 19.4 20.1 12.0 18.7 18.4 15.8 5.0 4.7 5.2 4.8 4.2 4.9 1.8 11.2 9.8 11.2 7.5 9.0 15.6 7.0 8.4 7.8 8.9 7.4 7.3 6.8 10.5 7.2 9.4 10.7 15.6 6.7 11.4 6.9 13.7 12.5 12.9 7.2 6.5 23.7 12.1 9.1 6.8 9.5 18.0 9.2 17.0 25.5 9.0 7.9 13.1 10.5 12.9 12.9 12.1 22.8 12.8 6.0 14.6 5.9 9.2 23.4 8.2 10.4 6.0 12.6 11.6 10.5 8.8 8.4 5.8 10.9 10.1 13.6 5.8 19.1 7.8 4.4 4.1 1.1 4.4 2.8 3.8 3.0 4.6 4.5 4.7 5.0 4.4 4.9 5.2 4.2 4.8 3.5 3.1 1.8 15.0 19.8 20.7 18.0 15.4 12.0 18.5 16.5 17.3 21.3 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "Transducin beta like 1 X-linked receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favourable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 20.7 26.0 27.4 24.3 26.8 27.3 20.3 27.5 28.1 28.9 29.9 22.6 15.4 24.0 23.9 20.5 23.8 21.9 22.7 30.3 26.2 20.7 19.9 21.8 30.8 27.8 21.4 25.9 26.5 19.9 30.6 11.3 24.0 19.7 24.4 23.2 24.7 21.3 17.7 21.1 17.8 24.3 21.9 19.6 24.7 21.3 17.4 22.3 28.4 45.6 14.9 32.1 29.1 25.5 7.4 13.3 12.9 4.6 6.8 8.3 4.1 23.4 12.0 15.6 8.8 13.3 14.5 9.3 7.4 11.5 6.4 8.9 13.8 19.4 24.0 35.1 10.6 14.5 11.7 15.5 13.0 25.2 3.7 13.5 20.6 8.2 11.4 21.4 8.0 21.3 8.0 9.5 23.6 10.0 10.1 42.6 8.3 8.4 20.0 2.9 9.9 8.2 11.5 19.9 25.6 5.8 33.2 5.6 9.0 10.0 7.9 9.3 28.6 16.4 15.3 10.6 8.9 5.9 16.0 23.3 29.8 69.5 7.1 16.0 12.0 11.4 3.0 3.8 5.8 4.6 5.1 7.3 5.7 6.6 4.0 7.4 5.0 6.4 12.9 6.8 3.9 13.3 8.3 4.1 27.4 26.8 27.5 28.1 26.2 20.7 21.4 25.9 19.7 22.3 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box 3" O15119 12 114670254-114684164 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 117.7" "Cell line enhanced" "Detected in many" "BJ: 33.8;BJ hTERT+: 32.2;RT4: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favourable (3.28e-4)" 4.3 60.5 0.9 3.3 1.9 0.0 19.9 0.7 2.3 18.2 12.2 1.7 69.6 14.2 13.1 18.7 1.9 7.5 5.0 6.2 1.2 1.5 4.1 15.1 12.6 0.8 1.2 0.5 15.6 1.1 0.3 5.3 67.8 1.6 32.3 1.5 2.6 7.3 117.7 4.2 4.8 19.4 9.7 1.4 2.6 2.2 3.5 1.2 0.5 36.3 7.3 3.5 24.6 25.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 5.9 0.0 0.0 8.9 12.3 13.4 33.8 32.2 13.1 13.0 5.3 1.4 0.0 0.5 5.8 1.5 2.8 1.2 16.2 0.0 4.0 0.0 1.5 15.4 2.9 0.0 0.0 5.4 0.8 4.4 9.1 0.1 1.2 0.0 1.1 0.5 0.0 0.1 0.0 1.8 0.0 0.0 0.8 0.0 42.2 2.2 6.5 4.8 2.2 1.1 1.6 0.0 0.0 4.0 2.6 2.2 10.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.9 0.7 2.3 1.2 1.5 1.2 0.5 1.6 1.2 TCF12 "bHLHb20, HEB, HsT17266, HTF4" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 89.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: " "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavourable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavourable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 20.9 14.3 24.9 12.6 37.5 10.9 18.4 32.7 41.8 48.2 16.5 33.6 14.0 16.0 28.1 15.0 14.8 28.2 21.4 15.7 28.4 16.4 17.0 14.4 17.3 13.7 33.9 15.3 26.2 12.5 29.2 15.7 19.1 27.9 26.3 17.9 14.7 20.1 17.5 18.1 16.0 15.8 25.8 25.3 13.6 17.3 14.7 41.3 89.4 17.0 9.6 15.8 23.3 21.2 11.8 15.9 16.0 19.3 12.2 17.6 10.2 6.5 12.3 54.2 17.5 24.7 21.7 9.5 13.5 23.8 12.0 16.0 8.0 5.3 9.0 11.1 20.4 7.9 21.2 9.7 15.4 11.8 7.9 18.1 13.4 9.5 17.1 11.3 9.5 19.1 17.6 11.0 29.2 21.4 20.2 11.4 16.3 2.2 26.7 6.3 14.6 5.3 36.6 63.0 8.4 16.5 12.2 11.1 32.1 14.6 5.3 13.1 8.2 22.3 16.5 19.4 14.8 8.2 19.7 6.5 11.6 15.0 10.8 22.1 23.1 16.0 11.2 8.7 15.0 14.3 12.4 10.8 12.2 13.6 15.9 11.8 14.1 12.7 1.3 12.2 19.3 6.6 17.6 10.2 24.9 37.5 32.7 26.9 28.4 16.4 33.9 15.3 27.9 41.3 TCF7 TCF-1 ENSG00000081059 "Transcription factor 7" P36402 5 134114711-134151865 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 326.1" "Cell line enriched" "Detected in many" 15 "MOLT-4: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "MAIT T-cell: 10.3;memory CD4 T-cell: 17.8;memory CD8 T-cell: 10.4;naive CD4 T-cell: 35.8;naive CD8 T-cell: 21.8;NK-cell: 14.2" "Group enriched" "Detected in many" 19 "NK-cells: 14.2;T-cells: 35.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019403, HPA058863, HPA070505" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB019403: AB_2199302, HPA058863: , HPA070505: " "unprognostic (3.63e-3)" "unprognostic (1.98e-3)" "unprognostic (1.03e-1)" "unprognostic (5.08e-3)" "unprognostic (1.70e-1)" "unprognostic (6.74e-2)" "unprognostic (1.12e-1)" "unprognostic (6.38e-2)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (2.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.90e-1)" "unprognostic (4.10e-2)" 1.8 3.6 1.3 21.8 1.5 5.2 3.1 0.9 1.2 2.1 3.3 2.5 2.2 5.6 1.4 16.3 2.7 16.1 2.6 1.6 1.5 1.2 2.7 3.7 4.0 41.8 1.3 1.0 2.5 7.2 0.2 6.1 1.4 4.7 2.9 2.3 3.6 7.9 1.8 0.9 2.9 15.1 0.9 3.3 14.4 3.7 2.4 1.1 326.1 4.4 2.2 32.5 3.3 1.5 1.2 0.1 1.0 0.1 14.2 35.8 6.9 0.0 1.0 1.1 3.8 0.5 2.1 1.5 0.3 0.5 0.1 0.1 7.9 2.5 0.0 1.9 1.7 0.1 1.7 0.4 0.0 0.3 1.6 0.0 1.0 5.9 0.0 0.0 0.2 0.1 0.0 1.6 0.0 0.2 1.0 0.0 0.1 0.0 166.9 0.1 1.2 1.4 0.2 0.0 0.1 0.4 0.1 0.4 3.3 0.8 0.2 0.2 0.2 0.9 0.2 10.8 0.0 4.9 0.3 0.1 0.0 0.0 5.7 0.0 0.5 0.7 0.1 1.0 4.4 0.0 10.3 1.2 17.8 10.4 0.0 0.4 35.8 21.8 0.7 14.2 0.0 0.1 2.1 6.9 1.3 1.5 0.9 1.2 1.5 1.2 1.3 1.0 4.7 1.1 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950250-113167678 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 12.1;non-classical monocyte: 33.1" "Lineage enriched" "Detected in many" 13 "monocytes: 33.1" "Group enriched" "Detected in many" 8 "midbrain: 84.5;thalamus: 98.3" "Group enriched" "Detected in all" 5 "midbrain: 190.1;pons and medulla: 104.8;thalamus: 169.1" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 27.4 10.3 8.7 18.7 10.0 7.3 46.4 5.4 10.3 27.4 34.2 15.4 28.1 21.0 26.6 14.9 12.6 18.2 15.3 13.5 8.1 17.9 10.2 22.9 26.9 13.9 8.5 9.0 25.6 13.9 16.5 17.9 24.0 10.2 14.4 23.7 13.9 14.9 52.8 13.7 17.6 40.4 18.0 13.9 27.3 24.0 10.6 10.1 6.6 14.3 9.3 7.0 21.5 16.3 0.0 1.7 2.5 33.1 0.0 0.6 1.1 7.0 18.5 20.3 19.6 10.6 7.1 24.2 5.0 9.8 3.5 4.3 12.2 21.5 0.0 5.7 9.4 5.0 6.9 8.7 4.5 0.8 6.4 5.0 12.3 11.3 11.3 1.9 1.8 12.5 3.2 5.5 9.3 5.9 5.1 0.3 4.1 13.8 3.1 1.2 14.6 10.7 8.9 14.9 3.2 7.6 9.9 0.4 6.2 7.6 7.6 8.1 4.9 1.0 13.6 3.3 9.6 8.4 10.3 1.3 0.1 0.1 3.3 4.2 7.4 0.1 1.8 0.1 0.6 12.1 0.4 0.0 0.1 0.5 1.7 0.0 0.1 0.3 2.5 0.0 33.1 0.0 0.0 1.1 8.7 10.0 5.4 10.3 8.1 17.9 8.5 9.0 10.2 10.1 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 29.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 9.9 6.1 8.7 11.9 11.4 26.3 8.0 4.1 10.0 9.6 7.4 10.1 5.8 8.2 10.1 7.4 16.2 9.2 6.6 6.8 9.0 4.2 6.7 5.5 9.9 9.8 13.7 5.7 8.5 7.0 7.4 29.0 12.4 9.1 6.5 8.0 4.7 13.5 8.2 9.8 16.0 10.2 7.8 15.5 12.9 6.8 3.2 14.6 9.3 7.2 6.9 8.7 9.8 12.3 2.8 5.1 29.0 7.0 2.6 2.1 1.4 4.7 3.1 10.4 10.6 1.9 4.3 4.3 3.4 4.6 4.9 4.8 3.1 6.4 0.5 3.9 4.3 4.6 10.1 6.0 5.6 6.2 2.7 6.6 5.9 1.1 5.3 15.1 11.1 3.6 8.1 4.7 6.1 6.5 7.1 12.5 4.2 3.6 2.5 4.1 2.3 1.9 7.8 5.2 0.9 4.5 10.0 7.4 6.1 3.8 9.8 0.6 4.4 10.9 8.4 7.5 6.8 2.1 5.8 8.4 6.0 6.3 4.6 3.7 7.3 10.8 7.0 7.2 2.1 5.5 0.8 2.6 1.2 1.2 5.1 2.8 1.0 1.6 29.0 2.6 6.4 4.5 1.5 1.4 8.7 11.4 4.1 10.0 9.0 4.2 13.7 5.7 9.1 14.6 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641470 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 20.4" "Low lineage specificity" "Detected in all" "CAB033605, HPA044754, HPA068909" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB033605: AB_783105, HPA044754: , HPA068909: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favourable (7.57e-4)" "prognostic favourable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 16.0 13.3 20.1 28.0 21.1 71.6 16.4 24.4 22.4 19.3 19.6 16.3 28.6 16.0 16.8 20.5 36.2 18.0 27.0 26.3 19.0 16.8 17.9 20.9 16.5 32.5 18.0 12.7 14.4 26.7 9.9 16.3 21.8 15.2 16.0 23.0 20.2 18.9 24.2 26.9 22.3 21.3 18.4 23.5 25.6 16.4 37.5 10.3 38.8 21.7 32.7 34.4 18.5 20.8 3.6 4.7 20.4 4.0 1.6 5.4 2.0 62.0 15.3 19.8 16.8 26.9 24.0 22.5 35.0 31.8 45.5 42.1 31.8 29.2 57.9 11.7 33.5 29.9 34.3 31.1 44.7 39.4 39.9 33.6 25.0 19.9 16.9 84.3 29.7 19.8 28.0 28.8 16.8 30.5 27.6 15.6 40.4 21.3 37.0 32.8 18.2 19.7 25.3 17.6 33.1 17.3 23.8 51.2 15.1 15.7 43.2 10.5 29.7 68.0 21.2 14.8 23.6 31.3 38.5 13.3 16.3 59.7 33.0 52.3 25.0 20.4 2.3 3.6 2.6 3.0 2.9 3.6 3.5 3.1 4.7 2.6 5.4 2.7 3.1 1.6 4.0 2.4 4.2 2.0 20.1 21.1 24.4 22.4 19.0 16.8 18.0 12.7 15.2 10.3 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.4 14.4 0.9 0.0 53.4 80.5 2.4 12.5 17.6 4.3 4.3 3.2 13.3 0.3 45.3 16.8 5.0 0.6 18.3 7.2 1.0 1.3 1.4 1.6 16.2 22.8 2.2 11.8 69.5 16.3 18.6 18.0 46.7 0.2 0.0 65.8 0.2 2.3 1.6 0.4 5.8 2.0 5.8 0.3 23.2 5.8 0.0 0.9 3.7 1.0 3.5 0.0 2.4 60.3 21.2 5.2 9.6 4.7 0.4 0.0 2.0 12.7 2.5 8.5 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm Nucleoplasm "HPA062160: " "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavourable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 31.9 16.6 6.9 17.2 9.3 11.2 22.0 2.7 6.2 26.8 23.8 15.5 48.4 9.6 32.7 47.3 27.1 24.8 31.4 12.9 6.5 7.2 24.7 33.6 27.9 10.6 8.1 5.9 23.0 20.2 5.3 10.2 49.6 9.9 33.2 22.4 15.3 25.1 29.8 21.2 22.9 16.6 18.5 8.6 23.1 19.8 23.1 9.2 18.1 60.2 11.2 21.0 40.5 29.0 18.2 14.0 20.4 17.3 7.4 27.5 12.7 6.1 28.3 18.6 5.9 19.0 25.7 45.5 11.9 45.7 9.8 12.5 11.2 28.4 0.3 4.0 9.7 6.4 7.1 13.4 12.9 2.5 2.9 0.8 13.5 21.1 35.7 8.9 7.4 17.8 57.5 17.7 47.2 20.8 6.4 0.1 19.1 12.1 5.8 11.0 47.4 6.2 6.1 8.3 2.0 40.1 30.5 5.2 5.2 31.5 24.7 17.4 5.7 8.0 8.9 15.3 13.3 18.0 7.4 1.0 0.1 2.8 15.7 3.4 19.2 20.4 17.3 2.9 25.9 6.5 27.5 18.2 21.6 25.2 14.0 12.8 15.5 18.0 7.8 7.4 6.1 1.4 11.4 12.7 6.9 9.3 2.7 6.2 6.5 7.2 8.1 5.9 9.9 9.2 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69255208 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 4.0" "Lineage enriched" "Detected in single" 8 "monocytes: 4.0" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" 790000 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: " "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favourable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 25.2 9.5 23.7 8.0 29.7 5.7 20.7 35.6 24.9 9.0 20.0 50.3 20.6 27.2 11.9 7.3 28.9 12.6 13.2 19.8 35.1 12.7 23.3 34.5 23.9 5.8 39.7 20.5 20.9 13.2 43.2 3.6 18.0 32.0 13.5 16.7 19.1 18.0 23.1 8.3 18.6 25.7 15.3 39.7 3.5 30.4 17.8 41.1 11.1 22.5 9.0 10.8 26.5 26.6 0.0 0.2 0.4 4.0 0.0 0.5 0.5 53.2 1.7 4.2 4.7 20.1 19.7 23.2 8.1 5.9 12.9 7.0 6.4 19.4 7.6 8.1 4.5 32.7 6.9 17.0 14.7 27.2 5.0 7.4 4.6 32.8 5.6 3.0 14.0 15.3 12.3 10.1 6.0 27.1 4.4 5.2 6.7 7.4 1.1 0.4 10.4 11.6 3.9 6.1 0.8 33.3 35.5 1.9 3.3 2.9 20.7 0.6 6.7 1.6 38.8 9.7 10.5 7.5 8.2 5.3 1.1 0.1 11.1 4.3 3.5 0.0 0.7 0.0 0.0 1.5 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.4 0.0 4.0 0.1 0.5 0.5 23.7 29.7 35.6 17.5 35.1 12.7 39.7 20.5 32.0 41.1 TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102590-23117437 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "blood: 173.4" "Group enriched" "Detected in some" 5 "BEWO: 37.1;HUVEC TERT2: 30.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "neutrophil: 173.4" "Lineage enriched" "Detected in many" 113 "granulocytes: 173.4" CAB025635 Enhanced "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" 5.5 1.5 1.9 14.0 3.6 12.6 2.0 1.4 3.9 2.9 1.5 0.7 0.1 1.2 1.5 1.2 1.4 3.7 13.5 5.6 1.9 1.1 2.8 3.2 13.7 28.4 9.2 0.0 2.4 2.1 2.5 4.5 12.8 3.1 2.7 1.8 1.7 1.7 0.8 2.3 0.8 2.2 1.9 4.4 26.4 1.8 1.4 2.3 0.8 4.4 0.5 0.9 5.2 1.9 0.0 0.3 173.4 1.5 0.0 0.0 0.4 0.4 1.4 0.5 2.4 0.0 0.3 37.1 1.5 0.0 0.1 0.1 0.0 1.4 0.1 0.7 1.4 0.2 0.1 0.1 0.1 2.5 0.5 0.1 0.3 1.1 3.6 0.2 1.0 4.1 0.3 0.7 0.3 30.9 0.0 0.0 0.2 1.0 0.0 0.9 1.6 0.0 0.1 0.1 0.0 5.9 0.1 0.0 0.0 0.1 0.2 0.7 5.1 0.2 6.5 0.6 1.2 1.4 0.1 1.5 0.8 0.0 2.2 0.3 0.9 2.7 1.5 25.4 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 173.4 0.0 1.1 0.0 0.0 0.4 1.9 3.6 1.4 3.9 1.9 1.1 9.2 0.0 3.1 2.3 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347994 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" 14000 Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: , HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favourable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favourable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 17.0 21.2 9.5 10.2 13.8 31.1 13.7 10.2 24.6 16.0 14.6 12.0 7.5 17.4 14.1 15.5 31.6 11.7 15.4 19.1 8.8 15.2 16.1 27.4 17.5 8.2 11.6 11.3 12.1 11.8 21.8 16.8 39.0 23.2 10.2 6.4 17.5 37.0 10.1 83.8 29.1 18.6 7.1 8.4 10.6 8.4 13.6 8.7 10.0 14.8 25.9 19.9 12.1 17.6 4.6 15.2 40.9 31.2 4.6 14.7 17.0 6.6 6.7 3.9 6.3 27.9 16.6 18.4 6.5 19.7 12.7 14.3 9.3 6.2 2.6 12.1 20.3 3.1 4.0 6.8 4.6 7.5 9.1 2.2 7.6 19.3 26.3 4.2 10.1 22.4 8.6 17.9 6.1 8.8 4.3 6.6 6.2 6.4 3.4 9.9 3.0 3.9 6.2 5.6 5.6 5.0 5.0 6.7 5.2 14.8 15.4 14.5 7.8 7.0 9.2 15.1 13.1 11.5 3.2 7.7 4.8 6.8 20.3 4.4 4.9 5.9 31.2 13.1 6.4 18.9 5.3 4.6 9.8 6.1 15.2 4.0 7.9 5.3 40.9 4.6 19.4 8.1 14.7 17.0 9.5 13.8 10.2 24.6 8.8 15.2 11.6 11.3 23.2 8.7 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease mutation, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favourable (1.39e-4)" "prognostic unfavourable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 12.5 11.6 10.9 12.5 14.0 23.8 12.0 21.4 17.9 11.0 11.2 13.8 9.1 10.3 13.3 10.4 12.1 11.8 9.5 8.4 9.3 10.5 9.3 15.6 10.8 15.5 9.4 9.0 11.4 16.1 15.0 15.1 10.7 11.1 11.0 13.1 12.8 11.6 9.0 13.0 19.1 10.8 14.1 9.0 16.6 10.5 17.9 11.8 25.9 10.3 7.4 16.2 11.6 10.7 2.1 2.7 10.4 5.9 4.1 4.0 3.3 8.1 13.7 11.2 13.6 5.7 5.8 10.2 8.6 6.2 15.2 15.0 24.9 3.6 14.1 5.6 7.8 11.5 16.8 7.3 16.1 10.4 13.5 12.9 14.2 8.5 5.7 6.4 11.5 3.7 4.7 16.1 9.4 7.0 11.1 5.8 8.8 8.4 14.3 8.1 8.7 7.6 16.3 26.7 13.3 4.5 8.4 8.0 15.0 13.2 8.3 8.5 16.6 6.8 6.7 10.9 8.7 20.7 14.8 6.4 11.5 9.9 6.8 8.9 10.4 1.4 5.9 6.5 4.0 5.8 2.6 1.7 3.0 3.1 2.6 2.1 2.6 2.7 10.4 4.1 2.9 2.7 2.2 3.3 10.9 14.0 21.4 17.9 9.3 10.5 9.4 9.0 11.1 11.8 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687550 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 102.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: , HPA051244: , HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favourable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavourable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 18.5 11.1 6.0 28.6 6.8 9.0 17.5 2.5 7.3 18.5 14.6 6.8 8.3 9.7 20.3 15.0 25.3 16.7 22.6 8.1 5.0 3.8 10.6 20.8 11.2 26.0 6.6 3.1 33.8 13.8 4.9 6.0 22.8 6.9 16.5 14.5 9.9 15.3 16.1 12.5 24.6 14.0 12.8 6.2 24.2 12.0 14.1 6.9 102.6 13.2 23.5 31.2 16.9 15.0 15.2 19.6 2.2 14.1 11.0 11.3 8.2 19.2 35.6 19.4 14.0 9.1 10.8 20.6 6.9 15.6 19.2 24.3 1.0 9.9 45.3 31.5 13.6 42.5 28.2 19.1 18.0 10.1 18.9 18.3 20.0 16.9 27.4 0.4 9.5 13.7 22.2 9.3 25.7 18.8 0.9 1.7 9.8 34.2 30.7 22.4 19.6 0.7 59.7 13.7 15.7 14.3 21.3 11.6 20.0 22.8 15.4 5.9 26.7 1.7 24.3 23.0 7.6 0.3 11.6 11.9 8.7 19.5 6.0 2.3 19.4 0.8 13.3 2.2 9.1 14.1 11.1 15.2 9.4 10.2 19.6 14.5 9.9 10.8 1.7 11.0 11.9 17.9 11.3 8.2 6.0 6.8 2.5 6.4 5.0 3.8 6.6 3.1 6.9 6.9 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133" Supported Enhanced "Nuclear bodies" "Nuclear bodies" "CAB004083: AB_10694558, HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 7.2 12.9 13.4 9.0 20.7 8.9 9.6 21.9 22.9 17.2 10.0 12.5 10.1 5.7 14.6 15.1 7.0 13.8 9.8 10.7 13.9 12.9 8.6 4.1 8.0 7.2 7.1 14.8 15.9 7.4 30.0 34.8 10.7 17.9 11.4 9.5 7.9 9.8 12.3 7.9 8.2 7.2 15.0 7.9 7.2 7.7 18.3 9.3 15.2 16.2 4.9 10.8 11.5 11.1 5.4 3.5 3.7 1.9 2.1 4.8 1.8 6.2 10.7 31.3 19.5 13.0 16.2 7.6 10.8 16.4 15.4 19.6 9.2 7.6 6.7 9.6 18.4 15.6 22.5 13.2 18.4 18.3 7.7 12.8 18.7 5.5 8.5 14.1 18.5 12.5 9.4 20.7 15.5 18.2 12.5 6.0 17.8 4.4 11.0 6.6 20.1 6.6 11.8 11.7 4.4 11.4 14.8 28.4 13.2 15.6 7.0 4.2 14.4 8.0 12.9 16.5 11.2 13.0 9.6 4.8 10.4 15.8 13.7 7.0 8.4 3.7 1.2 2.5 4.1 1.9 3.5 5.4 4.4 4.1 2.9 4.9 4.8 4.4 1.4 2.1 1.2 3.5 3.4 1.8 13.4 20.7 21.9 22.9 13.9 12.9 7.1 14.8 17.9 9.3 TPR ENSG00000047410 "Translocated promoter region, nuclear basket protein" P12270 1 186311652-186375693 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019661, HPA019663, HPA024336" Enhanced Enhanced "Nuclear membrane" "Nuclear membrane" "HPA019661: AB_1858215, HPA019663: AB_1858216, HPA024336: AB_1858217" "unprognostic (4.51e-2)" "unprognostic (9.87e-3)" "unprognostic (2.48e-1)" "unprognostic (7.56e-2)" "unprognostic (9.88e-3)" "prognostic favourable (4.71e-4)" "prognostic unfavourable (1.06e-4)" "unprognostic (1.71e-1)" "unprognostic (3.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-2)" "unprognostic (3.63e-2)" "unprognostic (1.31e-3)" "unprognostic (3.75e-1)" "unprognostic (4.19e-2)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" 21.5 17.3 14.3 26.7 21.3 21.6 19.0 24.4 17.1 21.7 24.2 7.3 27.1 12.9 20.8 23.5 18.5 16.9 16.8 28.3 13.8 10.5 18.7 20.6 17.9 20.4 14.1 16.6 24.7 17.8 44.2 29.1 29.7 15.1 22.2 17.7 9.1 20.2 30.1 33.1 20.5 21.1 21.2 16.4 26.1 18.8 35.0 17.8 39.5 21.7 19.7 21.4 25.1 19.1 19.1 19.8 50.3 15.2 10.7 16.9 5.2 22.0 19.1 28.7 16.6 23.0 20.6 30.2 25.4 17.0 18.0 16.8 28.7 18.9 25.9 19.7 17.2 29.0 21.6 17.4 22.2 19.4 23.6 34.5 30.9 20.1 12.4 36.8 22.6 15.7 10.6 27.1 21.1 21.2 41.5 23.4 19.1 19.1 18.2 9.8 31.6 6.7 21.7 22.5 22.4 14.7 26.6 15.6 24.8 29.6 19.7 15.9 21.9 23.5 29.7 18.0 17.1 19.8 30.7 25.7 30.0 23.7 11.5 18.8 16.1 29.5 12.0 21.9 15.8 10.0 13.3 15.2 13.8 12.7 6.8 19.1 16.9 11.7 50.3 10.7 15.2 19.8 15.3 5.2 14.3 21.3 24.4 17.1 13.8 10.5 14.1 16.6 15.1 17.8 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 81.8;tongue: 34.0" "Cell line enhanced" "Detected in many" "HaCaT: 11.2;HDLM-2: 23.8;PC-3: 13.2;TIME: 10.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 16 "cerebellum: 21.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 4.9;T-cells: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 1.3 0.9 0.1 0.9 0.5 0.5 3.4 21.7 1.3 2.5 0.8 0.3 1.1 0.5 1.0 6.4 13.0 0.6 1.7 2.2 0.1 0.8 2.2 0.5 0.9 0.6 0.2 0.2 0.6 4.2 1.6 1.9 0.5 0.5 2.0 0.6 0.6 5.9 1.1 81.8 9.5 0.6 0.9 0.3 0.8 1.4 0.9 0.2 0.1 3.3 34.0 13.5 1.6 2.9 0.7 0.8 0.1 4.9 0.5 2.2 1.1 6.1 2.9 0.0 0.3 0.5 0.5 0.1 1.4 0.0 0.5 1.2 0.2 8.0 0.4 4.3 1.7 11.2 3.2 9.2 0.1 23.8 1.3 0.5 7.8 0.1 1.6 0.0 1.3 0.1 7.1 0.2 4.6 2.6 0.3 1.3 0.2 0.8 0.3 0.2 0.0 13.2 0.3 4.2 0.9 3.3 0.0 0.3 0.7 2.9 0.1 4.0 0.7 0.2 10.8 0.1 2.4 0.4 4.2 1.9 0.2 0.7 0.3 0.4 1.0 0.0 4.9 0.1 1.4 1.9 2.2 0.4 1.2 1.4 0.8 0.7 2.2 1.8 0.1 0.5 1.4 0.6 2.2 1.1 0.1 0.5 21.7 1.3 0.1 0.8 0.2 0.2 0.5 0.2 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: " "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavourable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.2 4.4 10.6 5.0 22.7 29.8 12.1 11.3 13.5 9.1 10.5 2.8 4.8 2.8 8.5 15.4 3.7 1.7 5.3 18.9 7.8 2.5 1.5 11.8 3.5 11.8 3.7 4.2 13.9 5.6 32.2 10.3 8.0 0.3 1.9 22.0 2.3 0.0 2.6 2.6 4.0 2.8 6.4 9.4 8.9 5.5 4.8 19.5 9.6 2.5 5.0 1.5 0.5 18.6 17.6 11.2 12.7 13.3 0.0 0.6 3.6 62.5 2.4 4.1 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002570, HPA070684" Supported Enhanced "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA002570: AB_1078995, HPA070684: " "unprognostic (1.65e-1)" "unprognostic (2.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "prognostic favourable (1.78e-6)" "unprognostic (1.78e-1)" "unprognostic (5.08e-1)" "unprognostic (7.74e-2)" "unprognostic (5.55e-2)" 13.0 15.0 10.5 10.8 12.5 7.7 12.1 18.5 14.1 17.4 13.0 8.8 15.2 11.1 13.3 12.7 14.7 11.4 11.2 12.9 9.2 6.7 15.5 16.1 10.6 9.4 12.2 11.1 16.0 27.1 27.1 34.9 24.4 15.2 14.5 11.0 9.4 15.1 15.3 24.0 12.4 15.9 11.2 10.7 15.2 16.2 14.0 13.5 16.4 18.4 11.1 11.9 15.8 12.5 20.0 12.7 17.0 13.0 12.1 14.1 3.9 12.4 12.6 8.2 8.6 14.5 22.5 12.5 19.8 15.2 9.8 11.3 7.6 20.3 8.7 14.6 17.4 16.4 10.8 9.6 21.5 13.2 3.3 9.8 11.4 7.2 11.1 11.5 9.8 8.6 11.8 17.3 14.9 15.6 6.4 10.1 15.3 17.4 6.5 2.8 3.7 9.0 8.1 15.7 4.3 8.8 20.4 6.0 5.4 16.0 9.4 6.1 20.5 5.8 20.6 11.4 8.1 11.9 8.9 9.0 13.8 7.8 13.4 6.5 14.3 8.2 8.8 17.0 13.3 8.0 12.8 11.8 14.1 12.1 6.9 20.0 13.5 14.1 8.7 12.1 13.0 12.7 12.2 3.9 10.5 12.5 18.5 14.1 9.2 6.7 12.2 11.1 15.2 13.5 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047465-2089487 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: " "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favourable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 13.9 11.9 16.9 12.4 20.0 10.9 13.2 35.1 26.9 20.5 17.0 19.4 17.9 14.0 20.1 12.2 13.0 18.6 15.0 14.0 13.3 8.8 11.8 9.8 12.7 10.1 13.8 14.7 21.1 16.1 20.0 18.1 10.6 14.6 13.8 10.8 16.7 22.9 19.6 31.7 14.5 13.2 13.5 11.4 12.9 16.6 21.4 12.9 14.1 20.1 11.3 10.9 18.0 14.0 4.7 5.6 7.7 4.9 3.6 7.0 3.7 7.2 11.6 16.1 18.2 19.2 16.2 13.6 17.4 11.9 13.1 11.2 13.9 13.8 10.9 15.5 14.3 12.0 9.6 12.6 9.8 8.3 15.8 10.3 22.5 5.7 13.2 12.8 12.5 19.1 8.0 10.6 7.9 12.3 10.0 9.8 11.6 14.4 15.2 3.8 16.7 11.4 24.2 17.6 13.9 5.3 6.5 12.2 23.1 24.8 16.4 8.8 15.0 9.5 19.4 13.8 9.4 12.3 8.8 21.9 21.8 21.8 5.7 5.2 16.3 6.2 4.9 5.4 7.0 4.7 6.7 4.4 4.4 4.1 5.6 4.7 3.1 4.8 7.7 3.6 3.7 1.5 3.2 3.7 16.9 20.0 35.1 26.9 13.3 8.8 13.8 14.7 14.6 12.9 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184796-49189324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, Disease mutation, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 270.7;smooth muscle: 166.4" "Cell line enhanced" "Detected in many" "AF22: 222.1;SCLC-21H: 149.7" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 151.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules Microtubules "CAB008686: AB_1624202, HPA039247: , HPA043684: , HPA063394: " "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavourable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 27.8 25.5 82.1 29.4 81.3 24.7 35.4 63.2 163.0 40.6 48.8 210.9 6.9 9.9 71.7 34.8 27.7 65.3 37.9 26.3 99.3 118.3 10.3 4.2 39.8 13.4 131.0 50.2 35.7 9.9 16.0 20.6 23.1 165.2 35.1 26.7 16.7 13.6 53.4 5.9 20.0 14.5 166.4 270.7 11.6 18.3 15.7 50.4 19.4 7.4 7.3 10.6 35.1 14.5 14.8 28.9 151.2 69.2 7.5 15.7 38.4 0.2 10.0 222.1 31.6 20.2 48.9 0.8 18.7 24.0 12.3 28.7 0.6 4.0 7.9 23.3 60.5 0.4 26.3 6.8 9.6 6.6 9.0 2.6 2.0 2.2 3.9 4.7 0.2 27.5 2.6 24.2 2.5 72.9 3.1 9.0 65.9 4.4 20.1 3.8 23.4 7.4 16.2 15.9 1.0 55.0 0.9 149.7 81.9 5.2 0.3 7.1 15.7 6.4 62.0 13.2 8.3 1.5 5.4 3.1 8.7 15.9 7.2 7.7 13.1 38.8 23.0 73.1 15.7 48.9 11.5 14.8 13.9 14.3 28.9 14.6 13.6 12.5 151.2 7.5 69.2 9.3 15.2 38.4 82.1 81.3 63.2 126.2 99.3 118.3 131.0 50.2 165.2 50.4 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996600 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 110.2;HSkMC: 146.6;hTCEpi: 74.7" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 127.7 10.6 4.1 17.0 4.6 10.5 73.6 2.5 6.0 45.9 49.8 16.1 25.0 6.3 39.3 22.8 41.0 20.3 20.4 55.3 4.8 34.8 11.7 52.3 82.6 6.5 4.2 34.1 25.8 9.3 20.2 19.1 8.3 47.4 16.1 18.8 18.5 19.5 97.0 15.3 27.7 34.6 9.2 39.0 13.6 23.1 6.0 29.0 85.3 16.0 41.5 52.5 32.3 64.9 35.5 134.9 58.3 65.3 90.0 132.5 6.0 0.0 1.4 0.1 33.5 110.2 3.3 7.2 14.5 6.5 9.0 3.8 8.2 1.7 42.9 1.9 1.6 1.4 13.7 17.6 7.9 0.7 4.9 2.2 3.5 1.5 20.1 10.3 146.6 74.7 13.3 23.5 2.5 19.5 13.5 3.3 8.2 3.3 19.3 4.0 5.4 3.0 12.1 52.3 17.1 13.4 6.9 11.2 31.1 9.0 24.6 3.2 28.8 6.1 18.2 1.1 34.0 11.8 19.0 18.1 1.5 4.4 9.3 9.5 94.7 53.3 123.0 90.0 58.3 83.1 58.8 76.5 79.9 35.5 64.9 76.0 80.3 134.9 65.3 49.9 16.7 70.6 132.5 U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107587 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm Nucleoplasm "HPA044833: AB_10960990, HPA052083: " "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" 20.0 15.1 20.8 19.2 21.1 48.5 61.0 25.6 20.8 16.1 21.5 9.7 12.3 17.6 28.8 26.5 19.3 27.6 17.1 19.5 19.7 15.8 14.6 17.1 35.2 33.5 25.7 2.9 22.1 48.3 15.3 27.8 21.2 20.8 23.9 13.7 9.6 44.5 19.8 33.0 16.6 20.4 38.7 23.9 21.0 17.5 33.9 22.7 20.6 27.3 26.5 20.0 22.9 31.7 58.4 82.8 81.2 54.1 33.1 55.5 53.8 25.0 27.5 15.0 11.3 8.8 6.3 35.1 21.8 15.1 17.8 15.9 63.9 9.2 42.9 11.9 14.1 12.3 31.3 23.1 9.2 33.6 70.7 69.4 14.1 24.0 21.5 29.8 17.1 8.7 14.3 28.8 18.4 14.7 38.0 19.4 12.4 47.1 24.7 33.1 31.8 31.7 40.8 14.4 21.6 11.8 10.6 22.8 17.4 23.4 14.1 11.5 17.2 17.4 18.3 14.8 20.2 13.4 22.7 26.0 30.6 35.5 14.2 55.0 22.8 48.4 52.6 50.9 42.2 52.5 41.4 55.9 46.4 42.1 54.1 58.4 46.4 44.8 81.2 33.1 54.1 82.8 55.5 53.8 20.8 21.1 25.6 20.8 19.7 15.8 25.7 2.9 20.8 22.7 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142848 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Approved Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 14.9 13.9 15.9 11.4 19.9 31.9 10.8 16.9 26.0 9.5 10.0 8.7 5.3 9.9 9.3 8.8 10.2 8.0 10.6 10.4 18.0 13.7 14.7 28.0 10.6 9.7 14.8 12.0 11.1 4.7 21.5 15.3 13.7 22.6 11.1 9.6 6.9 8.7 11.2 26.2 8.4 11.1 11.2 13.7 11.8 9.0 15.2 9.8 10.0 13.0 8.1 8.1 16.7 8.4 3.8 8.4 22.9 8.4 3.7 3.7 3.4 11.3 12.4 6.9 7.1 10.7 15.2 13.8 17.7 17.9 14.4 10.5 9.1 3.9 9.8 4.6 18.1 4.4 12.9 6.0 14.0 26.1 6.3 6.6 9.9 10.6 9.9 12.3 10.8 8.6 5.1 17.2 12.0 10.0 5.2 10.3 14.0 6.3 7.9 10.7 11.9 11.3 9.0 12.3 9.7 7.3 20.1 11.8 7.3 13.5 15.5 5.2 13.9 14.2 7.9 15.9 8.5 13.7 12.4 12.2 20.8 13.8 8.0 9.4 9.6 12.5 7.6 4.9 2.6 8.4 3.7 3.8 2.9 2.9 8.4 3.4 2.5 3.0 22.9 3.7 6.8 5.1 3.2 3.4 15.9 19.9 16.9 26.0 18.0 13.7 14.8 12.0 22.6 9.8 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141008-10152220 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 53.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB005430, HPA031631, HPA031632" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB005430: AB_2241850, HPA031631: , HPA031632: " "prognostic unfavourable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favourable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 13.8 17.4 18.1 29.2 18.4 24.3 15.4 25.8 21.4 13.3 19.8 19.3 14.5 15.9 15.1 13.6 16.4 14.3 18.9 10.5 17.1 18.5 13.7 16.3 14.6 27.9 13.5 12.3 15.2 22.5 13.8 14.6 18.8 12.8 15.1 16.6 12.5 21.8 13.7 14.8 14.0 22.3 13.4 17.0 22.6 16.2 17.9 11.2 39.2 16.9 11.5 29.3 15.4 19.1 5.4 3.9 8.0 4.1 4.4 4.3 1.7 6.7 6.5 14.3 8.8 13.3 10.3 53.6 5.9 8.5 7.6 9.0 7.6 8.4 23.8 8.1 8.0 5.8 13.2 8.3 9.4 11.4 12.0 18.5 10.5 10.5 12.6 16.3 14.8 10.3 9.5 10.1 12.8 8.7 16.4 18.1 7.5 12.2 15.5 12.0 9.6 8.3 19.7 12.6 11.9 9.3 17.4 5.4 17.9 12.5 6.7 7.2 13.2 20.7 7.5 7.6 10.1 7.0 9.3 12.9 26.4 38.0 8.4 19.5 6.9 2.6 4.1 3.3 3.8 2.5 3.6 4.1 2.9 4.3 3.9 5.4 2.5 2.7 8.0 4.4 3.2 2.4 3.1 1.7 18.1 18.4 25.8 21.4 17.1 18.5 13.5 12.3 12.8 11.2 WRN "RECQ3, RECQL2" ENSG00000165392 "Werner syndrome RecQ like helicase" Q14191 8 31033801-31173769 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 10.1 9.2 5.6 8.5 6.6 15.6 11.1 10.7 7.3 14.2 8.0 7.7 7.7 5.5 24.4 8.8 7.6 9.7 6.9 7.0 5.9 4.0 5.1 7.7 7.2 6.7 8.2 5.3 12.0 9.9 7.8 28.1 8.5 7.0 8.6 7.8 8.3 10.8 7.8 7.7 10.2 7.0 12.1 14.9 8.9 8.3 10.4 7.3 11.8 7.9 6.3 9.3 10.8 8.7 3.9 2.7 1.3 1.9 2.9 6.2 1.6 6.4 6.3 13.1 8.3 7.8 12.5 8.3 7.3 7.1 8.9 9.3 4.0 3.9 15.1 6.7 7.3 3.3 8.1 5.2 13.4 4.2 6.9 15.4 6.0 3.3 9.8 9.1 5.7 9.1 5.8 8.5 10.2 8.6 24.3 9.6 8.2 4.1 18.9 4.4 11.2 4.6 10.9 9.9 6.0 3.7 7.0 2.8 7.5 8.8 5.0 6.9 3.5 4.5 13.7 9.7 6.0 5.0 6.1 2.5 2.7 19.0 7.2 7.2 6.6 1.2 1.9 1.3 3.3 1.9 6.2 3.9 3.8 3.3 2.7 3.5 2.5 3.2 0.5 2.9 0.8 2.0 2.8 1.6 5.6 6.6 10.7 7.3 5.9 4.0 8.2 5.3 7.0 7.3 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "Wilms tumor 1" P19544 11 32387775-32435630 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 69.0;fallopian tube: 34.5;ovary: 53.4" "Cell line enhanced" "Detected in some" "HEL: 13.2;HMC-1: 17.0;K-562: 11.9;NB-4: 31.9;THP-1: 15.3" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons and medulla: 0.5" "Low region specificity" "Detected in single" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB000327: AB_2304486, HPA035717: , HPA053848: " "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 10.3 0.0 0.2 1.8 0.6 0.0 0.2 0.2 0.5 20.3 1.5 0.2 3.7 0.0 69.0 9.3 0.4 34.5 0.8 2.1 0.9 0.0 5.3 0.2 0.8 0.5 0.2 0.2 53.4 0.2 0.0 0.2 6.9 0.3 0.9 0.0 0.2 0.2 4.2 0.2 0.0 0.4 23.7 0.2 14.6 0.0 24.5 0.2 0.2 0.3 0.2 0.2 1.3 4.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.1 0.0 0.0 6.1 0.0 0.0 0.0 4.6 13.2 0.0 1.1 3.7 8.8 17.0 0.0 0.0 2.7 0.0 0.0 11.9 0.1 2.7 0.0 7.7 31.9 0.7 3.7 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 15.3 0.1 0.0 2.3 0.0 0.3 0.0 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 0.2 0.5 0.9 0.0 0.2 0.2 0.3 0.2 ZFHX3 "ATBF1, ZNF927" ENSG00000140836 "Zinc finger homeobox 3" Q15911 16 72782885-73891871 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059353 Uncertain "HPA059353: " "prognostic unfavourable (1.55e-4)" "unprognostic (3.57e-2)" "unprognostic (1.68e-1)" "unprognostic (2.03e-2)" "unprognostic (2.81e-2)" "unprognostic (3.12e-1)" "unprognostic (4.24e-2)" "unprognostic (6.36e-2)" "unprognostic (9.94e-3)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "unprognostic (4.16e-2)" "prognostic favourable (1.37e-5)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-2)" 7.9 6.0 2.5 2.3 4.6 1.1 11.3 1.5 4.1 7.5 7.7 5.4 14.5 2.0 7.4 7.3 4.5 4.9 18.2 4.9 4.3 4.8 4.4 6.5 6.1 1.4 4.0 2.6 4.4 5.7 23.8 6.3 8.1 5.5 12.0 3.5 10.5 5.0 19.5 16.9 3.6 3.6 15.5 9.7 3.9 5.0 2.3 5.2 0.5 10.8 4.0 1.0 16.7 14.7 0.8 1.0 0.2 1.6 2.5 0.1 0.2 4.4 7.8 12.7 10.5 4.7 6.0 13.1 3.4 3.7 2.1 2.4 8.8 2.5 1.9 5.9 6.3 3.1 8.0 4.0 3.0 7.7 1.9 0.3 10.6 12.6 4.4 1.3 3.2 2.2 2.4 6.3 5.7 4.0 0.9 0.5 5.4 9.1 0.4 2.6 2.2 1.3 5.8 3.4 0.6 3.5 7.4 9.5 3.4 5.9 1.8 4.2 2.6 0.6 8.7 5.3 6.3 5.6 4.4 4.9 1.6 1.3 2.5 1.2 4.0 0.2 1.6 0.2 0.1 0.9 0.1 0.5 0.0 0.0 0.7 0.8 0.0 0.1 0.2 2.5 1.1 1.0 0.1 0.2 2.5 4.6 1.5 4.1 4.3 4.8 4.0 2.6 5.5 5.2 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 212.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 212.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 59.0 22.4 40.2 42.4 35.0 14.2 89.9 16.3 31.0 91.5 60.2 49.6 24.8 26.0 90.6 37.5 66.8 59.9 36.5 36.2 45.1 15.3 34.6 46.0 45.6 39.0 32.7 16.7 121.7 47.1 63.4 14.8 62.7 44.9 65.3 21.9 29.9 60.3 43.7 31.6 90.2 28.5 91.2 47.3 33.9 42.2 26.9 39.4 22.1 43.3 22.7 57.1 81.2 93.2 37.0 8.7 212.7 17.7 10.4 16.1 14.4 38.8 37.3 15.5 22.4 39.3 31.6 34.3 16.5 27.4 9.6 12.1 16.3 25.8 9.4 10.0 28.4 18.0 1.4 51.0 11.8 4.4 2.2 3.4 18.7 11.5 22.4 0.5 4.3 26.6 65.5 11.7 76.7 19.3 9.6 18.5 51.1 9.2 1.4 1.7 12.9 5.4 24.9 20.8 2.8 35.3 28.0 0.1 0.4 18.6 26.8 13.8 24.6 0.4 44.1 28.6 21.0 22.6 15.7 10.4 5.2 6.5 35.5 0.2 10.8 14.2 17.7 0.2 16.1 17.2 15.0 19.7 12.9 11.2 8.7 37.0 14.1 12.4 212.7 10.4 11.4 1.1 12.0 14.4 40.2 35.0 16.3 31.0 45.1 15.3 32.7 16.7 44.9 39.4 ZFP36L2 "BRF2, ERF2, RNF162C, TIS11D" ENSG00000152518 "ZFP36 ring finger protein like 2" P47974 2 43222402-43226609 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047428 Approved "HPA047428: AB_10963428" "unprognostic (2.07e-2)" "unprognostic (1.81e-2)" "unprognostic (9.77e-2)" "unprognostic (6.10e-2)" "unprognostic (9.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-1)" "unprognostic (7.62e-3)" "unprognostic (2.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.67e-3)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (2.50e-1)" "unprognostic (4.52e-2)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" 57.9 32.6 10.1 65.3 30.1 47.3 104.4 3.6 16.8 43.9 41.2 20.8 24.8 31.4 35.4 32.5 35.4 40.6 78.8 36.3 18.1 9.1 23.1 26.1 74.0 112.5 15.4 11.0 63.7 29.5 6.6 13.7 8.6 70.6 39.2 38.4 27.9 31.7 49.0 33.3 64.9 52.2 40.7 74.2 44.2 34.4 14.8 12.8 76.5 73.3 32.6 39.8 50.1 43.9 11.2 22.0 32.5 17.7 22.4 28.6 10.1 7.6 3.7 3.7 2.0 47.3 48.5 1.5 11.2 20.4 4.8 3.7 13.1 3.6 5.5 8.5 12.9 14.5 3.9 19.5 4.1 9.9 8.3 8.9 1.4 13.8 14.1 19.4 7.8 34.0 32.0 4.9 32.1 8.5 8.9 22.1 4.7 40.7 22.9 40.5 5.7 6.6 17.2 2.8 31.9 8.2 11.1 3.3 8.4 2.1 13.0 6.7 2.2 32.2 4.0 13.1 5.7 11.0 6.8 18.7 5.1 8.3 4.4 48.8 6.0 7.2 17.7 32.5 21.6 14.7 21.2 8.1 21.3 28.6 22.0 11.2 16.2 15.5 27.5 22.4 11.5 9.5 7.8 10.1 10.1 30.1 3.6 16.8 18.1 9.1 15.4 11.0 70.6 12.8 ZMYM2 "FIM, MYM, RAMP, ZNF198" ENSG00000121741 "Zinc finger MYM-type containing 2" Q9UBW7 13 19958670-20091829 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031765 Approved Approved "Nucleoplasm,Endoplasmic reticulum" "Nucleoplasm, Endoplasmic reticulum" "HPA031765: AB_10601927" "unprognostic (2.96e-1)" "unprognostic (3.42e-3)" "unprognostic (1.85e-1)" "unprognostic (1.69e-1)" "unprognostic (7.71e-2)" "unprognostic (2.33e-1)" "unprognostic (2.66e-3)" "unprognostic (1.16e-1)" "unprognostic (6.78e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (2.80e-2)" "unprognostic (6.65e-3)" "unprognostic (2.05e-1)" "unprognostic (8.74e-2)" "unprognostic (1.06e-1)" "prognostic favourable (6.07e-4)" 15.0 17.3 15.9 18.1 23.3 22.2 16.1 23.9 26.8 18.3 16.8 14.0 13.7 13.3 20.0 14.0 18.5 16.1 15.7 17.1 14.4 12.0 17.3 13.7 15.4 14.2 12.9 20.2 21.7 16.2 17.1 32.1 14.0 23.2 19.4 13.8 13.8 18.2 17.6 19.7 18.3 14.5 15.3 16.2 16.3 16.0 44.5 16.5 38.0 24.3 10.4 19.7 19.5 17.2 5.5 6.3 7.4 5.9 5.4 7.9 3.5 6.3 5.7 22.0 9.5 9.7 10.5 10.5 6.6 10.6 8.6 10.3 8.8 13.1 15.2 6.1 9.3 10.2 16.2 7.1 11.7 6.1 4.6 26.9 8.6 4.4 9.8 22.7 8.2 10.3 13.3 6.8 7.1 14.6 10.2 10.8 11.8 9.0 21.9 6.4 20.4 3.6 24.5 24.0 7.1 6.7 9.3 25.8 25.7 12.8 9.2 12.0 12.2 16.2 8.5 4.3 6.8 5.2 3.5 8.6 6.7 15.7 3.6 5.3 10.2 0.2 5.2 4.0 5.5 5.9 6.7 5.5 7.5 5.6 6.1 4.5 7.9 6.9 7.4 5.4 4.9 6.3 5.4 3.5 15.9 23.3 23.9 26.8 14.4 12.0 12.9 20.2 23.2 16.5 ZNF132 pHZ-12 ENSG00000131849 "Zinc finger protein 132" P52740 19 58432814-58440222 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008726 Uncertain Approved "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA008726: AB_1080664" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (6.79e-3)" "unprognostic (3.06e-2)" "unprognostic (8.16e-2)" "unprognostic (4.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.32e-3)" "unprognostic (5.00e-2)" "unprognostic (1.29e-1)" "prognostic favourable (1.92e-4)" "unprognostic (4.51e-1)" "prognostic favourable (7.26e-13)" "unprognostic (2.70e-1)" "unprognostic (7.65e-2)" "unprognostic (6.09e-2)" "unprognostic (3.72e-1)" 2.9 4.7 4.0 2.5 5.9 0.8 5.1 11.8 8.5 5.9 4.1 6.6 4.5 2.5 4.2 7.2 3.5 7.9 4.7 5.9 6.0 4.5 6.2 2.1 3.6 3.3 4.4 5.5 7.6 4.3 15.3 12.1 3.7 5.9 6.1 2.4 5.4 5.8 6.7 3.7 4.7 2.6 5.9 4.2 4.5 3.6 7.2 6.0 3.1 10.8 2.8 4.3 5.7 6.3 3.9 2.9 2.0 2.6 2.6 5.7 2.1 1.7 2.1 4.8 1.7 5.6 4.6 0.2 3.6 4.5 3.0 2.7 0.1 1.4 4.5 0.3 4.4 1.8 0.0 5.4 2.1 0.7 8.2 0.8 1.4 1.0 5.0 1.7 3.0 5.1 1.9 5.1 3.2 2.6 0.7 0.5 5.6 0.6 1.0 0.1 4.9 1.7 0.6 1.1 1.3 1.8 2.0 4.3 4.4 1.4 1.3 1.5 0.3 4.4 3.3 3.1 0.4 0.8 0.7 5.9 1.1 0.0 1.5 0.1 1.9 0.0 1.9 2.0 2.2 2.2 5.7 2.9 2.9 1.2 2.9 3.9 4.6 3.7 0.2 2.6 2.6 2.4 2.5 2.1 4.0 5.9 11.8 8.5 6.0 4.5 4.4 5.5 5.9 6.0 ZNF300 ENSG00000145908 "Zinc finger protein 300" Q96RE9 5 150894392-150904983 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 17.2;HeLa: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 3.8" "Low lineage specificity" "Detected in all" "HPA028975, HPA051777" Uncertain Supported "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA028975: , HPA051777: " "unprognostic (5.06e-2)" "unprognostic (1.05e-2)" "unprognostic (8.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.15e-1)" "unprognostic (6.23e-3)" "unprognostic (4.21e-2)" "unprognostic (3.23e-1)" "unprognostic (8.62e-2)" "unprognostic (6.85e-3)" "prognostic unfavourable (3.21e-6)" "unprognostic (3.62e-3)" "unprognostic (2.99e-1)" "unprognostic (3.46e-1)" "unprognostic (1.50e-2)" 4.5 1.3 4.8 4.0 12.0 3.6 7.2 12.5 6.4 7.4 4.3 5.4 4.1 4.1 11.7 5.3 7.5 5.4 5.4 4.0 7.5 3.2 7.3 1.5 3.0 4.4 8.2 2.4 16.6 7.3 1.0 7.3 2.4 7.4 7.0 4.4 3.6 3.8 3.9 1.5 6.9 5.8 6.4 9.2 5.1 7.1 14.9 9.1 1.5 9.3 2.7 4.4 5.5 6.2 3.8 1.2 1.1 1.5 1.7 1.0 0.8 1.2 2.8 17.2 0.0 1.5 3.6 0.0 4.2 3.3 3.7 5.4 1.4 2.1 0.0 3.7 3.5 2.5 0.0 9.6 5.8 0.0 5.6 0.0 18.9 2.2 3.1 0.1 0.0 5.5 3.0 7.7 9.1 6.3 0.0 9.1 3.6 0.0 0.0 0.8 16.5 0.0 0.0 2.5 4.9 2.7 3.1 9.7 16.1 9.9 8.6 5.7 5.7 0.0 2.7 5.0 2.1 3.6 7.6 0.3 0.1 0.0 0.5 0.1 10.3 0.0 0.6 1.1 0.7 1.5 0.1 0.9 1.0 0.0 1.2 3.8 0.7 0.4 0.2 1.7 0.1 0.1 0.0 0.8 4.8 12.0 12.5 6.4 7.5 3.2 8.2 2.4 7.4 9.1 ZNF814 ENSG00000204514 "Zinc finger protein 814" B7Z6K7 19 57848731-57889074 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 21.8;U-266/84: 20.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (3.74e-2)" "unprognostic (1.24e-1)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (6.01e-2)" "unprognostic (2.12e-2)" "unprognostic (1.03e-1)" "unprognostic (4.69e-2)" "unprognostic (6.78e-4)" "unprognostic (5.05e-3)" "unprognostic (2.41e-4)" "unprognostic (1.56e-2)" "unprognostic (4.99e-4)" "unprognostic (3.94e-1)" "unprognostic (2.33e-1)" "unprognostic (1.08e-1)" "unprognostic (1.54e-5)" 5.6 13.3 11.6 9.0 11.0 12.6 12.2 19.2 10.8 6.4 10.0 4.4 15.7 9.7 5.6 10.5 5.2 12.5 9.8 9.5 11.5 10.3 15.0 11.7 5.9 11.1 9.1 8.4 7.8 6.7 10.9 16.2 9.7 7.7 11.4 7.3 16.1 9.0 18.4 18.6 13.3 12.7 9.0 7.3 13.8 5.5 14.0 5.6 18.7 23.0 4.0 11.5 6.6 5.0 21.2 15.3 5.0 5.0 12.8 13.6 4.5 0.9 2.4 7.4 11.0 0.8 0.7 1.9 2.7 1.9 3.1 0.4 1.3 1.0 5.5 1.8 2.5 0.8 0.5 6.0 3.8 0.8 5.0 4.2 3.3 1.3 3.3 4.7 5.2 5.0 5.3 1.2 1.1 0.9 1.0 2.1 4.7 0.9 15.6 2.1 21.8 3.1 1.8 0.8 9.8 2.4 3.9 2.8 7.9 0.9 1.8 3.7 5.4 1.4 1.4 6.9 2.3 1.5 1.2 6.5 20.0 14.0 1.5 2.5 8.2 2.2 4.5 5.0 3.2 5.0 8.2 19.4 8.4 6.9 6.6 21.2 13.6 11.0 2.7 12.8 2.9 15.3 2.1 4.5 11.6 11.0 19.2 10.8 11.5 10.3 9.1 8.4 7.7 5.6 ZNF844 FLJ14959 ENSG00000223547 "Zinc finger protein 844" Q08AG5 19 12064699-12081565 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 11.3;U-266/84: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA046982 Uncertain "HPA046982: AB_10964399" "unprognostic (2.07e-1)" "unprognostic (1.50e-2)" "unprognostic (1.75e-1)" "unprognostic (8.95e-2)" "unprognostic (2.92e-3)" "unprognostic (9.68e-3)" "unprognostic (1.93e-1)" "unprognostic (1.87e-2)" "unprognostic (1.86e-2)" "unprognostic (5.86e-2)" "unprognostic (2.47e-2)" "unprognostic (6.74e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.99e-1)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (3.63e-2)" 9.5 5.2 7.2 6.0 10.8 9.7 12.0 26.9 7.8 10.3 8.6 7.8 11.4 4.3 13.2 7.2 9.4 11.9 4.0 10.3 8.5 5.1 17.2 6.5 6.3 8.1 10.1 7.2 21.2 8.1 14.3 21.3 6.6 9.5 13.4 8.6 10.5 9.3 10.9 12.7 7.9 6.2 14.9 12.5 6.3 6.7 8.8 12.2 3.6 18.7 3.9 5.1 12.8 12.5 2.8 1.9 6.3 3.6 3.1 3.6 1.4 0.1 0.1 3.2 5.4 4.4 4.3 2.4 3.9 1.3 4.0 3.5 4.9 0.9 4.1 4.2 3.1 1.3 0.0 0.7 3.8 0.1 0.2 7.3 0.3 1.2 3.4 0.4 5.5 3.8 0.5 2.3 0.1 0.1 0.1 0.4 2.5 0.1 3.4 1.2 4.2 0.4 0.3 11.3 1.0 1.4 0.2 2.5 2.0 0.0 1.9 1.2 5.8 0.4 0.2 1.2 3.0 5.0 4.1 7.4 16.0 0.6 0.1 0.5 0.8 6.3 2.0 5.3 1.7 3.6 0.9 2.8 1.2 1.6 1.9 2.1 3.6 1.9 5.8 3.1 2.0 0.6 0.4 1.4 7.2 10.8 26.9 7.6 8.5 5.1 10.1 7.2 9.5 12.2 ZNF91 "HPF7, HTF10" ENSG00000167232 "Zinc finger protein 91" Q05481 19 23304991-23395560 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "unprognostic (2.53e-1)" "unprognostic (3.60e-2)" "unprognostic (4.94e-2)" "unprognostic (1.18e-2)" "unprognostic (3.32e-3)" "unprognostic (5.62e-2)" "unprognostic (1.99e-3)" "unprognostic (5.85e-2)" "unprognostic (9.85e-4)" "unprognostic (6.74e-3)" "unprognostic (3.02e-2)" "unprognostic (4.47e-2)" "prognostic favourable (7.58e-4)" "unprognostic (7.38e-3)" "unprognostic (1.09e-1)" "unprognostic (2.21e-2)" "prognostic favourable (3.48e-4)" 9.5 11.0 16.2 13.4 20.1 5.5 15.6 47.0 21.1 14.2 17.0 8.6 11.9 19.9 12.8 13.6 11.9 11.4 7.4 10.0 15.7 8.5 13.0 11.4 9.8 12.3 16.6 11.8 16.4 9.5 17.6 32.7 23.2 16.9 13.3 17.9 8.4 13.7 13.9 15.6 12.1 21.6 9.4 18.3 11.1 11.8 6.5 18.7 10.2 17.8 6.0 11.2 13.8 11.9 9.1 6.3 5.1 3.4 5.3 12.6 3.4 4.1 0.7 13.3 6.3 3.9 6.2 7.4 3.0 5.0 7.8 9.7 3.3 4.2 0.2 6.3 3.8 5.2 10.4 3.2 9.7 0.4 10.1 1.8 3.2 2.5 3.1 0.1 3.3 5.2 6.3 6.1 7.4 2.7 6.3 0.9 5.8 2.4 12.0 4.6 9.2 3.7 9.1 8.6 6.9 4.7 10.3 8.1 6.4 0.2 0.3 3.4 3.9 7.7 3.7 2.4 1.4 3.6 5.6 0.4 3.4 12.3 0.1 0.3 1.3 4.5 2.2 2.7 7.4 1.8 6.6 6.8 8.8 7.7 2.6 9.1 12.6 9.6 5.1 5.3 3.4 6.3 4.9 3.4 16.2 20.1 47.0 21.1 15.7 8.5 16.6 11.8 16.9 18.7