Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4" Q8TB40 14 22598237-22613215 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm Nucleoplasm "HPA000600: AB_1078081" "unprognostic (5.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.68e-3)" "unprognostic (8.17e-2)" "unprognostic (1.17e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-3)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.73e-1)" "unprognostic (1.56e-2)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" 17.2 24.9 12.8 6.4 14.5 10.0 20.5 12.3 13.9 19.4 14.7 21.4 37.5 13.4 26.0 26.2 28.6 14.4 22.4 16.4 14.1 10.4 23.9 17.0 13.6 8.7 18.9 12.9 15.4 11.4 14.8 12.2 15.9 15.5 19.3 12.8 22.2 13.9 35.5 17.9 14.2 26.3 22.8 18.5 11.9 18.5 45.0 16.4 5.1 25.1 11.1 14.7 23.2 20.7 3.8 2.8 18.6 4.2 4.4 6.0 3.4 8.0 13.5 5.5 5.0 44.8 16.3 5.3 3.6 18.5 9.1 17.0 8.1 12.9 0.7 9.6 15.8 15.7 3.5 9.4 7.5 5.9 1.2 3.0 9.4 26.8 20.5 0.4 10.9 20.6 7.4 11.9 10.2 9.3 2.2 14.7 8.3 4.4 0.2 0.4 6.7 9.8 2.2 4.9 3.3 10.6 8.6 0.3 1.1 24.3 8.7 9.3 3.4 0.9 6.6 4.0 5.5 6.4 1.4 15.9 8.2 0.2 3.0 0.6 3.1 18.6 4.2 6.6 6.0 3.2 5.0 3.8 3.9 3.9 2.8 2.4 1.3 2.6 17.4 4.4 2.9 0.4 2.3 3.4 12.8 14.5 12.3 13.0 14.1 10.4 18.9 12.9 15.5 16.4 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 70.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 26.1;classical monocyte: 7.6;neutrophil: 21.0" "Group enriched" "Detected in many" 5 "granulocytes: 26.1;monocytes: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Approved Vesicles Vesicles "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favourable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favourable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 26.5 10.5 5.2 7.4 12.2 32.2 70.3 8.5 10.3 7.6 10.2 10.5 5.9 7.4 4.6 4.0 22.7 3.7 10.4 9.8 7.4 4.5 10.1 18.4 14.1 8.7 18.5 4.6 4.2 12.8 9.1 8.6 20.2 14.9 5.8 6.7 4.4 21.1 7.4 10.4 24.8 15.1 8.1 19.0 7.0 8.9 8.1 12.5 3.3 13.2 9.9 6.7 11.2 16.0 1.7 3.6 26.1 7.6 0.9 2.4 2.5 8.3 2.9 3.5 3.7 14.9 5.7 7.3 34.2 13.6 9.4 7.1 4.6 2.9 7.0 4.7 10.7 2.8 5.5 8.3 9.6 25.3 5.4 17.8 11.4 3.1 7.4 4.0 5.8 6.3 28.9 15.8 13.5 15.7 10.6 5.3 20.9 4.5 2.9 2.8 9.5 9.6 1.2 10.2 4.0 12.2 16.7 4.4 5.9 15.0 8.1 3.5 8.7 3.5 8.7 8.3 6.6 15.4 14.8 4.8 13.3 3.3 8.9 7.4 6.4 26.1 7.6 4.4 1.2 3.7 1.0 1.7 0.9 1.4 3.6 1.2 0.8 1.3 21.0 0.9 2.7 0.9 2.4 2.5 5.2 12.2 8.5 10.3 7.4 4.5 18.5 4.6 14.9 12.5 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745334 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "testis: 106.3" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;HUVEC TERT2: 1.1;NTERA-2: 1.7;TIME: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA048687 Enhanced "Secreted in male reproductive system" "HPA048687: " "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 0.9 0.0 0.2 0.2 0.3 0.0 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.1 0.3 0.7 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.3 0.6 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.4 0.2 0.2 0.2 0.2 0.2 0.2 1.2 0.0 106.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674002-49683963 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol 1600000 Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favourable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 12.3 31.4 14.3 16.9 18.4 17.3 13.5 14.2 28.2 13.4 23.5 14.4 25.3 24.2 14.1 19.0 23.8 17.2 19.1 23.1 14.2 14.2 33.6 36.9 15.0 23.9 13.9 20.0 13.9 22.7 33.5 26.6 18.6 16.3 16.1 26.6 19.5 19.8 19.8 55.1 16.9 21.7 14.1 9.8 19.2 21.9 22.3 11.7 22.6 26.6 26.6 20.7 19.9 13.7 20.5 26.2 30.4 27.9 21.8 29.5 28.1 25.4 20.8 22.8 29.6 19.9 13.4 30.2 16.6 21.4 23.4 25.1 33.4 27.6 32.6 18.7 18.9 23.6 25.4 38.5 17.8 15.5 10.5 35.1 34.7 27.3 19.8 37.6 54.7 15.2 29.2 13.4 27.8 21.1 21.7 16.2 23.2 23.5 26.5 19.1 13.5 19.0 10.1 19.6 42.3 46.3 60.4 10.9 18.9 18.8 45.7 20.7 30.1 20.1 9.6 14.5 25.4 22.6 22.4 18.6 13.2 19.4 25.0 26.6 20.8 30.2 25.5 30.4 28.5 27.9 22.5 20.5 23.5 26.7 26.2 17.4 24.9 24.2 8.0 21.8 26.7 21.0 29.5 28.1 14.3 18.4 14.2 28.2 14.2 14.2 13.9 20.0 16.3 11.7 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 238.2" "Cell line enriched" "Detected in some" 7 "THP-1: 150.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.3;neutrophil: 7.6" "Group enriched" "Detected in many" 6 "granulocytes: 7.6;monocytes: 3.3" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" 290000 Vesicles "HPA055851: , HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.3 0.2 0.4 0.2 0.5 238.2 0.6 0.0 0.6 0.2 0.2 1.0 0.0 0.2 0.2 0.2 0.2 0.8 0.2 34.6 0.4 0.5 0.2 1.5 15.3 0.2 0.2 0.0 0.5 0.1 0.1 0.9 3.8 0.2 0.2 0.2 0.2 0.6 0.2 1.0 0.4 0.2 0.2 0.1 18.6 0.2 1.2 0.0 20.6 1.3 0.0 0.2 0.1 0.4 0.0 0.8 7.6 3.3 0.0 0.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 150.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 3.3 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 7.6 0.0 0.5 0.0 0.0 4.1 0.4 0.5 0.0 0.6 0.4 0.5 0.2 0.0 0.2 0.0 C1R ENSG00000159403 "Complement C1r" P00736 12 7080209-7092607 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.2" "Cell line enhanced" "Detected in many" "ASC diff: 177.7;ASC TERT1: 90.7;BJ hTERT+: 78.2;BJ hTERT+ SV40 Large T+ RasG12V: 48.2;HSkMC: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 2.0;gdT-cell: 1.6;MAIT T-cell: 2.0;memory CD4 T-cell: 1.4;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.8;naive CD8 T-cell: 2.9;neutrophil: 2.5;NK-cell: 3.2;T-reg: 1.4" "Group enriched" "Detected in many" 6 "granulocytes: 2.5;NK-cells: 3.2;T-cells: 3.4" "Low region specificity" "Detected in all" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol "Secreted to blood" 14000000000 "Nucleoplasm, Cytosol" "HPA001251: , HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavourable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 45.8 17.4 2.6 18.1 3.8 0.0 82.0 1.4 2.8 36.7 24.5 2.4 11.2 5.0 27.2 66.8 38.1 33.3 46.7 49.5 1.9 1.8 27.5 370.2 25.3 46.8 3.5 2.0 103.5 11.4 1.4 6.3 10.3 4.6 47.8 15.3 17.7 12.8 13.2 16.0 10.7 14.4 53.2 6.2 35.1 19.8 39.3 1.9 2.3 30.6 20.7 15.1 46.8 83.8 0.4 0.0 2.5 0.4 3.2 3.4 0.8 0.1 1.5 0.1 1.3 177.7 90.7 0.1 19.9 78.2 23.7 48.2 0.2 0.3 0.0 0.6 15.6 0.2 1.7 0.8 3.3 1.8 0.1 0.0 0.6 0.6 34.2 0.1 0.2 105.0 0.5 10.8 0.8 0.4 0.0 2.5 3.1 0.0 0.8 0.1 0.8 0.1 1.1 0.5 0.1 0.1 0.9 0.0 0.3 14.4 0.4 0.4 0.0 0.0 0.0 5.6 0.9 26.1 0.1 0.1 0.4 0.0 8.1 0.1 0.8 0.0 0.4 2.0 1.6 0.1 2.0 0.0 1.4 3.4 0.0 0.4 2.8 2.9 2.5 3.2 0.0 0.0 1.4 0.8 2.6 3.8 1.4 2.8 1.9 1.8 3.5 2.0 4.6 1.9 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109273 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.6;HSkMC: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA011338, CAB026172" Supported Approved Microtubules,Cytosol "Secreted to blood" 5500000000 20000000000 Microtubules Cytosol "CAB026172: , HPA011338: AB_1847111" "prognostic favourable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavourable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 16.5 31.2 3.8 10.0 5.5 6.1 14.2 1.2 4.9 12.1 13.5 3.2 10.5 6.0 12.4 14.9 13.3 14.5 14.7 10.0 2.5 1.6 21.4 96.1 14.2 13.1 4.5 2.7 21.3 23.8 5.2 15.7 4.2 6.4 16.5 7.2 11.3 16.9 11.5 11.1 7.8 9.5 15.4 9.3 12.7 11.1 7.2 4.7 2.8 14.4 8.1 7.0 15.5 16.4 2.2 1.7 11.7 2.5 0.6 1.4 0.9 2.2 5.9 0.6 5.9 18.4 31.6 4.2 3.7 17.2 3.6 11.3 3.8 10.3 0.9 3.2 2.9 5.0 1.6 6.4 1.5 9.3 0.3 3.5 5.9 8.8 14.9 0.7 17.2 35.0 12.0 2.3 7.4 3.9 2.8 2.2 2.3 0.1 0.5 0.7 1.1 0.1 2.0 0.0 0.7 10.5 10.0 0.4 1.3 12.6 1.5 2.2 1.5 3.1 3.3 3.4 6.3 3.9 0.6 1.7 0.7 0.1 6.4 2.5 1.5 7.2 1.5 8.0 1.4 2.3 0.6 2.2 1.4 1.0 1.7 1.1 0.9 0.8 11.7 0.6 2.5 0.9 0.8 0.9 3.8 5.5 1.2 4.9 2.5 1.6 4.5 2.7 6.4 4.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 351.6" "Cell line enhanced" "Detected in some" "ASC diff: 97.0;ASC TERT1: 129.2;BJ hTERT+: 41.1;HSkMC: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "neutrophil: 6.2" "Lineage enriched" "Detected in single" 17 "granulocytes: 6.2" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" 93000000000 13000000000 Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favourable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 48.7 16.6 3.3 18.7 4.1 0.0 55.7 1.9 3.1 35.3 31.1 2.9 12.7 6.8 32.2 50.0 38.3 46.4 47.2 34.4 2.5 1.1 18.0 351.6 31.4 21.1 6.3 3.2 98.8 15.5 1.9 6.0 8.5 6.5 52.1 18.6 26.1 14.6 12.4 18.2 14.7 19.2 47.6 8.8 32.5 24.6 37.2 2.3 3.2 30.5 22.7 18.8 48.6 73.0 0.2 0.1 6.2 0.3 0.2 0.1 0.0 0.0 2.2 0.1 1.2 97.0 129.2 0.4 17.5 41.1 9.3 17.0 0.0 0.2 0.0 2.4 21.7 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.6 4.6 29.2 0.2 0.1 68.6 0.3 7.5 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 10.6 0.2 0.2 0.0 0.0 0.0 4.3 0.3 16.5 0.0 0.0 0.0 0.1 9.3 0.1 0.2 0.6 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 6.2 0.2 0.1 0.1 0.0 0.0 3.3 4.1 1.9 3.1 2.5 1.1 6.3 3.2 6.5 2.3 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 132.7" "Group enriched" "Detected in some" 5 "Hep G2: 16.9;Karpas-707: 52.8" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "classical monocyte: 2.9;intermediate monocyte: 6.4;non-classical monocyte: 6.5" "Lineage enriched" "Detected in single" 8 "monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016775 Supported "Secreted to blood" 52000000000 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavourable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 9.2 3.2 0.9 4.8 1.5 0.8 5.0 1.2 1.3 2.0 5.3 1.8 1.6 2.5 2.0 4.8 1.9 3.3 3.2 5.4 0.8 0.8 13.1 132.7 19.4 13.1 1.2 0.3 2.7 2.1 0.8 2.8 7.6 1.7 1.8 4.3 2.9 2.4 1.5 0.7 1.6 6.6 3.5 1.8 12.1 1.9 2.0 1.0 1.8 1.2 0.8 3.4 2.7 1.5 0.2 0.5 0.8 6.5 0.1 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 16.9 0.3 0.0 0.2 0.9 0.1 0.2 0.0 0.0 0.1 52.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.3 0.6 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 2.3 0.1 0.1 0.2 0.2 0.0 0.2 6.6 1.0 0.2 0.3 0.0 0.1 2.9 0.0 0.1 6.4 0.1 0.1 0.1 0.1 0.5 0.2 0.3 0.2 0.8 0.1 6.5 0.0 0.1 1.2 0.9 1.5 1.2 1.2 0.8 0.8 1.2 0.3 1.7 1.0 CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase family member 1" Q9UNI1 12 51328443-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 6.3;blood: 12.6;pancreas: 11.8" "Cell line enriched" "Detected in some" 4 "BEWO: 10.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Cell type enhanced" "Detected in many" "basophil: 9.0;naive CD4 T-cell: 12.6" "Group enriched" "Detected in many" 7 "granulocytes: 9.0;T-cells: 12.6" "Low region specificity" "Detected in all" "Secreted - unknown location" "unprognostic (3.54e-2)" "unprognostic (1.64e-1)" "unprognostic (4.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.59e-2)" "unprognostic (3.83e-3)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" 0.0 6.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 11.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.9 9.0 1.6 0.2 12.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 9.0 1.6 0.1 1.1 0.8 0.4 0.3 2.7 0.8 0.9 0.0 12.6 5.9 0.2 0.2 0.9 0.0 0.3 1.3 CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase family member 2A" P08217 1 15456728-15472091 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1559 "pancreas: 2376.3" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;HEL: 1.2;HL-60: 1.0;HMC-1: 4.9;K-562: 1.1;U-2 OS: 1.6" "Cancer enriched" "Detected in single" 3819 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "neutrophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Secreted to digestive system" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 2376.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.7 1.2 0.0 0.0 0.0 1.0 4.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase family member 2B" P08218 1 15465909-15491400 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 188 "pancreas: 697.9" "Cell line enriched" "Detected in some" 5 "U-138 MG: 9.1" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 3.7;neutrophil: 1.2" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.7" "Secreted to digestive system" "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 697.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.7 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.7 0.9 1.8 0.7 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 9.1 0.0 0.0 0.0 0.9 0.1 0.3 0.4 0.0 0.0 3.7 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase family member 3A" P09093 1 22001656-22012539 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2051 "pancreas: 2541.2" "Cell line enriched" "Detected in single" 24 "MOLT-4: 21.1" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 2541.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase family member 3B" P08861 1 21977021-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "pancreas: 1614.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1614.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.9 5.3 8.2 3.0 2.3 3.2 0.9 0.6 4.9 1.7 1.3 2.5 1.5 2.2 1.1 1.8 1.7 1.7 5.3 2.7 5.4 2.6 1.4 1.6 1.0 0.5 0.0 2.4 4.1 2.4 4.9 3.9 1.3 1.9 3.2 2.3 2.4 1.4 0.0 2.4 2.5 5.5 0.4 2.5 2.1 1.5 1.3 3.5 3.6 0.9 4.2 0.0 3.6 3.1 1.7 3.4 0.8 0.3 2.5 2.8 3.6 2.9 1.6 2.3 1.0 4.8 4.7 2.4 1.8 4.7 0.6 5.1 2.5 1.8 3.1 3.0 2.0 3.7 2.2 2.8 1.4 5.9 3.2 3.0 8.2 2.3 1.7 5.3 2.9 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 461.5" "Cell line enhanced" "Detected in some" "ASC diff: 6.0;ASC TERT1: 5.8;CAPAN-2: 6.9;fHDF/TERT166: 11.3;HSkMC: 18.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" 878700000 180000000000 "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: , HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favourable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 9.3 1.0 0.3 4.1 0.4 0.3 2.4 0.2 0.4 1.3 9.0 0.4 0.9 3.2 0.5 3.7 2.2 4.0 8.9 3.3 0.2 0.0 16.1 461.5 2.5 2.1 0.7 0.1 2.8 5.8 0.4 1.0 4.0 1.0 4.0 1.6 2.6 3.1 0.3 0.5 0.5 4.7 2.6 0.6 0.8 4.1 1.4 0.3 0.3 1.8 0.5 1.7 1.6 0.4 0.1 1.6 0.0 0.8 0.0 0.2 0.0 0.0 1.8 0.1 0.1 6.0 5.8 0.0 0.0 0.3 1.5 0.6 0.0 6.9 0.1 5.1 11.3 0.0 0.0 1.9 1.4 0.4 0.3 0.4 0.3 0.5 0.0 0.7 0.1 18.7 0.1 0.9 0.6 0.2 0.2 0.7 0.1 0.1 0.1 0.4 0.3 0.1 0.2 0.4 0.2 1.6 0.0 0.0 0.0 0.5 1.2 0.2 0.0 0.2 0.0 0.2 0.5 0.3 0.3 0.5 1.9 0.5 3.1 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 0.4 0.2 0.3 0.2 0.0 0.7 0.1 1.0 0.3 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859643-863630 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "ASC diff: 39.8;THP-1: 56.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 125.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 731723333 8000000000 "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favourable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 161.3 4.6 0.0 16.4 0.0 5.6 96.7 0.0 1.7 44.2 35.2 0.2 42.2 10.9 8.9 89.8 54.1 15.6 59.0 102.0 0.0 0.0 1.9 2.3 34.0 6.2 0.0 0.0 13.7 6.0 1.7 0.1 20.2 0.1 102.0 4.3 3.4 22.7 15.1 40.5 35.8 16.5 97.3 0.1 3.7 19.7 33.6 0.0 0.8 52.6 55.6 9.0 83.7 130.3 0.6 5.6 125.0 25.8 0.1 1.0 10.4 0.7 1.9 0.0 0.3 39.8 6.2 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.5 0.2 0.0 0.0 1.1 2.8 0.0 1.7 0.6 0.6 0.3 1.0 6.3 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.9 0.0 8.9 0.1 2.8 0.2 0.0 0.9 0.0 0.1 0.3 0.3 0.8 0.2 0.0 1.1 56.5 0.0 0.0 0.9 0.4 0.1 1.7 0.7 0.0 0.0 3.3 0.0 125.0 18.2 58.8 0.7 20.1 1.0 0.6 0.5 0.9 5.6 0.2 0.7 0.8 43.2 0.1 25.8 0.5 0.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109802179 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 90.7;liver: 198.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.9;Hep G2: 45.8;HSkMC: 19.0;RPTEC TERT1: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" 11000000000 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.06e-4)" 9.5 13.2 1.5 2.3 1.4 0.0 3.9 0.9 2.5 5.0 4.1 1.1 2.9 4.9 5.0 12.0 4.4 9.7 9.3 6.2 1.6 0.8 90.7 198.4 7.2 3.1 1.8 0.7 10.6 7.6 0.5 3.8 3.2 2.6 3.9 0.7 6.8 3.6 3.6 1.4 0.5 4.6 3.0 3.0 7.8 1.7 3.6 1.6 0.5 5.3 2.3 1.4 3.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 28.9 0.0 9.2 0.0 0.0 0.0 0.0 0.0 9.7 0.3 0.0 0.1 45.8 2.0 0.0 0.0 19.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.4 0.9 2.5 1.6 0.8 1.8 0.7 2.6 1.6 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361452-6368910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favourable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 22.1 27.3 18.4 22.5 18.8 20.1 19.9 16.6 20.9 16.1 23.2 17.9 22.2 25.4 16.9 15.1 26.6 15.3 19.2 28.9 17.4 16.7 28.5 64.7 15.5 35.5 19.0 15.2 23.7 32.7 11.6 18.5 18.4 13.6 19.1 14.1 18.6 26.3 23.4 73.1 17.8 26.0 14.8 16.7 21.2 21.3 21.1 11.4 54.8 27.0 25.1 25.3 20.7 23.2 29.7 37.5 14.9 20.0 27.6 46.3 32.9 31.6 21.1 15.4 28.1 9.7 13.5 16.0 18.8 13.8 26.8 24.0 16.9 11.6 31.9 29.3 15.0 19.8 15.2 23.7 10.1 33.1 47.9 23.5 18.6 25.0 26.3 21.2 31.1 17.1 17.4 18.6 20.8 26.0 23.2 43.2 17.5 37.0 36.3 22.2 22.2 49.4 25.6 18.6 48.3 19.9 17.7 25.5 24.4 11.9 29.1 27.6 15.0 30.4 18.1 17.7 16.4 41.6 35.4 55.6 46.4 30.7 24.3 29.9 28.1 5.5 20.0 10.5 28.0 17.7 33.2 28.3 39.9 34.5 24.1 29.7 35.2 34.1 14.9 27.6 12.1 37.5 46.3 32.9 18.4 18.8 16.6 20.9 17.4 16.7 19.0 15.2 13.6 11.4 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 1.6;BEWO: 1.5;HL-60: 1.7;TIME: 1.5;U-937: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced "Secreted to blood" 3000000 "CAB000363: AB_2083616, HPA052634: " "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.9 1.1 1.1 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.8 0.0 0.8 1.5 0.0 0.3 0.3 0.3 0.9 1.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593998-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 11.6;heart muscle: 39.5" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 31.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "pons and medulla: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.7" "Low region specificity" "Detected in single" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: " "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.3 0.1 0.3 0.0 0.1 0.0 0.8 0.1 0.1 3.1 0.1 0.1 2.6 0.0 3.4 11.6 0.7 1.2 4.5 39.5 0.0 0.2 2.0 0.0 1.3 0.0 0.2 0.0 0.6 0.1 0.0 1.5 0.6 1.6 1.7 0.0 0.4 0.3 4.6 0.2 5.3 0.4 0.5 0.0 3.5 0.3 3.7 0.0 0.2 0.1 1.7 0.4 0.8 3.2 0.2 0.0 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 7.3 31.8 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.2 0.0 1.6 0.0 CPVL ENSG00000106066 "Carboxypeptidase, vitellogenic like" Q9H3G5 7 28995231-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.9;lymphoid tissue: 84.0" "Cell line enriched" "Detected in many" 4 "RPTEC TERT1: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 95.8;intermediate monocyte: 81.6;myeloid DC: 111.9" "Group enriched" "Detected in many" 52 "dendritic cells: 111.9;monocytes: 95.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 510000 "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: , HPA056466: " "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavourable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavourable (4.99e-4)" 19.0 6.2 4.0 15.0 9.1 11.9 7.7 11.6 3.4 9.1 10.0 7.7 4.2 7.6 6.9 20.4 6.4 7.2 10.2 30.2 6.1 4.4 39.1 12.3 13.5 30.5 6.6 2.3 10.1 8.5 0.2 6.1 31.3 20.1 8.4 6.0 15.8 3.5 5.2 7.9 5.1 13.3 8.1 9.7 84.0 4.7 10.6 4.2 29.7 51.9 5.0 8.1 11.0 15.7 0.1 111.9 1.9 95.8 0.5 0.3 74.4 0.2 0.0 3.2 0.0 0.0 0.0 30.9 0.0 0.0 0.3 0.0 9.3 0.0 0.0 14.7 0.1 0.5 8.2 0.6 0.1 0.0 7.6 10.4 0.1 22.3 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 6.9 0.0 0.2 0.0 9.6 0.0 5.0 2.5 0.0 0.0 0.0 129.2 3.5 1.9 1.5 8.5 20.2 15.6 2.4 7.7 0.0 0.0 0.1 0.0 1.8 2.8 31.1 0.1 0.0 3.9 3.3 1.0 95.8 0.4 0.2 81.6 0.3 0.1 0.1 0.1 111.9 0.1 0.1 0.1 1.9 0.5 26.0 2.9 0.1 74.4 4.0 9.1 11.6 3.4 6.1 4.4 6.6 2.3 20.1 4.2 CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75219000-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2272 "pancreas: 1908.8" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 4.9;U-2 OS: 2.4;U-251 MG: 1.6" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 1908.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.2 1.6 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204096-75207185 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5240 "pancreas: 3761.5" "Cell line enhanced" "Detected in some" "EFO-21: 5.0;HDLM-2: 1.9;U-2 OS: 9.0;U-251 MG: 1.9;U-266/84: 2.6;U-698: 2.4" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 3761.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 0.0 1.9 0.1 2.6 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438439-15449242 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 417 "pancreas: 1443.7" "Cell line enhanced" "Detected in some" "A-431: 3.6" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" "HPA046920: " "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1443.7 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.4 3.4 0.7 1.5 0.6 0.1 3.6 0.6 0.5 0.7 0.2 0.0 0.2 0.3 0.4 0.0 0.0 0.0 1.7 0.5 1.1 0.0 0.5 0.0 0.1 0.2 1.1 0.5 0.4 0.3 0.1 0.9 0.2 1.7 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.2 0.5 1.0 1.6 0.4 0.0 0.5 0.1 0.3 0.0 0.1 0.4 1.0 0.4 0.2 0.2 0.3 0.1 0.9 0.4 1.4 0.9 0.2 0.8 1.6 0.3 0.8 0.8 0.3 3.4 0.4 0.4 0.4 0.2 0.2 0.3 0.3 0.6 0.1 1.1 0.3 0.4 1.7 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932414 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 281 "pancreas: 639.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 639.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1.1 1.1 0.7 0.0 2.2 0.5 0.5 3.7 1.1 0.3 0.2 0.1 1.8 0.3 0.7 1.1 1.3 2.3 1.4 0.7 0.4 0.7 1.0 5.6 0.7 3.1 1.4 6.3 0.7 1.1 1.4 0.3 0.9 2.5 1.2 0.2 3.9 1.0 0.0 1.5 1.0 0.6 1.0 0.7 2.7 6.2 2.2 2.8 0.5 4.5 0.0 0.9 2.6 1.4 1.3 0.7 0.6 1.2 4.3 1.6 0.1 2.0 0.5 1.6 6.5 2.7 3.6 0.2 0.8 0.8 0.6 0.7 0.3 1.5 0.7 0.2 0.3 1.1 0.5 0.9 0.6 0.5 2.2 1.1 0.0 0.7 1.1 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898820 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 125.7" "Cell line enhanced" "Detected in all" "ASC diff: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068" Enhanced Enhanced Vesicles "Intracellular and membrane" 18000000 Vesicles "CAB024930: , HPA031068: AB_10601205" "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 29.0 125.7 12.0 22.8 19.5 22.1 35.3 11.4 30.0 14.1 50.6 17.4 16.2 29.4 18.2 19.3 20.7 12.7 28.0 32.6 11.5 11.6 88.2 43.8 28.4 38.9 12.3 16.1 23.9 19.2 28.3 16.5 47.7 15.7 18.2 50.5 30.1 20.5 15.1 19.3 28.2 40.6 19.6 11.9 38.8 19.7 14.3 11.2 8.0 18.1 24.9 22.4 23.3 18.7 7.0 16.6 81.1 46.1 12.0 31.2 50.0 14.4 14.9 2.8 12.7 116.2 60.2 6.4 20.8 55.4 22.8 29.7 27.9 38.9 3.1 24.1 38.9 23.1 7.5 14.0 14.3 6.0 7.0 8.2 10.4 48.6 25.9 13.0 33.9 47.8 16.9 14.7 3.3 24.8 8.1 47.8 24.7 29.7 3.3 12.0 2.8 35.4 5.2 14.5 17.2 18.2 12.7 5.6 5.3 34.6 60.6 58.0 14.8 18.7 22.8 45.8 10.7 25.9 16.3 23.6 29.7 2.2 82.5 17.3 18.8 60.6 46.1 81.1 7.5 26.6 31.2 7.0 12.9 13.2 16.6 3.6 4.7 6.9 24.7 12.0 17.7 6.6 23.9 50.0 12.0 19.5 11.4 30.0 11.5 11.6 12.3 16.1 15.7 11.2 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573522-24576260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "bone marrow: 450.3" "Cell line enriched" "Detected in some" 7 "THP-1: 437.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.5;memory CD8 T-cell: 3.5;myeloid DC: 5.1;naive CD8 T-cell: 1.8;neutrophil: 7.1;NK-cell: 5.2;plasmacytoid DC: 5.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" 67000 "CAB000110: , HPA047737: " "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favourable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (8.91e-4)" 15.1 0.5 0.0 6.0 0.0 450.3 6.0 0.0 0.6 10.0 5.1 0.0 2.8 1.1 6.2 19.7 6.4 0.8 16.7 23.4 0.0 0.0 2.1 2.0 9.2 3.7 0.0 0.0 1.5 3.4 0.8 0.5 3.0 0.0 8.2 3.2 2.6 6.3 6.9 1.1 19.5 8.9 14.9 0.0 10.7 3.2 2.8 0.0 15.6 0.5 12.0 5.1 2.9 3.3 0.0 5.7 7.1 6.5 5.2 3.5 12.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 64.9 0.0 0.0 6.5 0.0 1.1 1.0 0.0 0.0 1.0 3.5 5.1 0.0 0.0 1.8 7.1 5.2 0.0 5.7 0.0 12.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845752 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 15.6;brain: 30.3;pancreas: 23.4" "Cell line enhanced" "Detected in some" "AF22: 5.0;HAP1: 7.5;HMC-1: 5.3;NTERA-2: 4.5;RT4: 8.0;SCLC-21H: 11.9;SH-SY5Y: 4.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain "HPA048767: " "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" 0.7 15.6 13.4 1.1 15.9 0.9 0.9 1.9 30.3 1.3 3.6 7.9 0.0 2.4 1.4 0.8 0.8 0.9 1.9 0.8 17.5 9.9 1.1 0.9 1.0 0.7 7.1 21.3 0.9 23.4 0.7 1.5 1.8 10.8 0.8 4.6 0.0 1.0 0.8 0.7 0.9 2.4 1.9 12.7 0.7 1.5 2.1 10.3 0.0 1.6 0.0 0.8 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 8.0 11.9 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 15.9 1.9 30.3 17.5 9.9 7.1 21.3 10.8 10.3 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992241-162074542 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 133.1;parathyroid gland: 75.5" "Cell line enhanced" "Detected in some" "ASC diff: 41.8;ASC TERT1: 42.4;BJ hTERT+: 38.9;RPTEC TERT1: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 26.7" "Lineage enriched" "Detected in many" 10 "T-cells: 26.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB045970 Enhanced "Secreted in other tissues" 170000000 "CAB045970: AB_11140529" "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.98e-4)" "prognostic favourable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favourable (4.99e-4)" "unprognostic (1.21e-2)" 9.5 2.9 0.3 3.2 0.5 0.0 5.0 0.3 1.4 2.2 50.0 0.2 36.9 19.1 2.2 3.5 1.2 1.2 5.2 2.1 0.4 0.3 29.1 12.2 5.4 2.1 0.4 0.2 2.7 1.8 75.5 0.3 24.0 0.2 21.1 2.8 0.6 46.9 38.8 2.4 4.4 133.1 0.9 0.8 5.0 1.2 0.6 0.1 6.2 1.0 1.4 1.1 1.0 2.6 0.1 2.1 0.3 0.0 2.6 26.7 2.5 0.0 0.0 0.1 0.0 41.8 42.4 0.1 7.7 38.9 2.1 7.6 7.8 0.2 0.0 2.9 13.4 0.2 0.1 0.0 1.3 2.4 0.1 0.0 0.0 11.7 17.1 0.0 0.0 4.8 0.0 13.1 0.1 1.2 0.0 0.0 0.7 0.0 0.7 0.1 0.4 16.0 0.0 0.0 0.1 56.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.9 4.5 0.2 0.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 26.7 0.1 8.3 5.2 0.6 0.0 8.3 3.3 0.3 2.6 0.0 2.1 0.9 2.5 0.3 0.5 0.3 1.4 0.4 0.3 0.4 0.2 0.2 0.1 DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153887097-154894285 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;endometrium 1: 24.5;thyroid gland: 24.1" "Cell line enriched" "Detected in some" 9 "NTERA-2: 11.0" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported "HPA050509: " "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" 1.6 7.2 15.4 1.4 32.5 1.3 1.5 26.6 45.7 2.3 6.8 8.7 0.0 1.6 24.5 3.1 1.5 4.6 1.3 1.4 26.6 15.2 3.6 1.2 2.2 1.3 14.0 22.7 1.3 4.0 1.2 4.9 1.3 18.8 1.5 2.4 0.4 1.3 8.1 4.6 3.7 2.0 15.8 7.2 4.2 3.5 7.9 10.0 0.0 24.1 0.0 1.2 1.3 0.4 0.6 0.6 1.9 0.9 0.9 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 11.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.9 0.4 0.7 0.4 0.6 0.7 0.6 0.6 0.4 0.4 0.6 0.7 0.7 1.6 0.9 0.9 0.6 0.5 0.3 15.4 32.5 26.6 32.4 26.6 15.2 14.0 22.7 18.8 10.0 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 56.7;THP-1: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1300000 "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: " "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favourable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 28.1 45.2 23.7 23.4 35.3 31.8 20.8 23.5 27.5 21.5 22.0 24.9 40.7 23.2 17.5 35.8 19.1 27.0 30.2 44.7 24.6 29.2 21.0 29.9 25.6 34.8 29.7 25.9 14.3 55.4 23.3 42.5 21.9 24.2 28.8 6.9 32.8 73.1 41.6 25.3 26.9 17.8 22.8 21.7 29.1 24.4 30.9 26.8 18.9 41.2 17.5 24.7 21.3 16.6 20.0 60.8 12.2 43.1 19.2 36.8 38.2 6.8 10.9 0.9 0.9 13.5 10.8 1.4 10.4 17.0 6.9 4.5 10.3 5.7 13.6 11.4 6.8 14.9 8.0 2.0 0.3 13.3 0.5 6.2 15.0 0.3 30.2 16.8 34.9 13.3 8.3 3.0 6.2 9.0 13.6 10.6 4.6 19.0 8.4 16.0 3.7 10.7 12.4 0.1 56.7 11.0 7.7 17.4 12.1 12.0 31.6 29.4 11.3 54.5 10.9 17.7 6.0 11.2 7.2 13.0 7.4 3.6 21.2 10.2 7.9 6.8 43.1 12.2 34.4 37.6 35.5 19.7 31.1 29.6 41.7 20.0 28.1 25.1 2.6 19.2 22.6 60.8 36.8 38.2 23.7 35.3 23.5 27.5 24.6 29.2 29.7 25.9 24.2 26.8 DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol Cytosol "HPA008706: AB_1078665" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (4.09e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (7.58e-2)" "unprognostic (8.56e-2)" "unprognostic (2.59e-1)" 15.6 16.1 16.4 14.9 18.8 16.2 13.9 22.9 24.9 15.5 14.5 15.0 12.7 18.0 15.9 13.9 13.1 11.1 12.4 18.8 15.1 14.6 16.0 9.9 13.3 16.0 15.4 11.8 16.2 11.7 22.2 14.5 15.9 21.7 13.5 15.8 13.9 15.6 20.8 30.5 14.2 16.5 16.2 17.5 17.2 13.2 29.9 15.8 22.5 17.4 12.5 16.0 16.2 13.2 10.7 8.1 20.0 10.8 6.1 10.3 5.3 9.4 15.3 10.1 10.1 11.4 16.4 8.6 15.3 18.1 13.7 13.2 6.6 8.2 16.7 12.1 19.1 17.7 19.5 11.0 16.8 14.1 12.1 16.1 11.8 6.3 11.9 20.7 15.9 12.2 10.5 11.1 10.5 15.0 10.9 15.6 16.8 7.6 11.0 7.6 6.9 7.9 14.7 18.7 16.2 11.3 20.6 7.2 12.7 9.9 10.1 15.4 9.3 12.4 18.9 18.4 12.9 8.7 16.3 20.2 26.4 17.0 13.9 20.9 13.2 20.0 9.1 11.1 9.9 9.2 10.3 9.2 8.6 9.5 8.1 10.7 8.6 9.2 18.3 6.1 10.8 7.5 8.9 5.3 16.4 18.8 22.9 24.4 15.1 14.6 15.4 11.8 21.7 15.8 DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4675224-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol Cytosol "HPA036059: AB_10671240" "prognostic favourable (4.96e-4)" "unprognostic (4.16e-2)" "unprognostic (2.03e-1)" "prognostic favourable (6.21e-5)" "unprognostic (5.67e-2)" "unprognostic (8.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-1)" "unprognostic (3.39e-2)" "prognostic unfavourable (3.38e-8)" "prognostic favourable (7.72e-5)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (1.80e-1)" 18.1 11.9 11.7 24.3 14.0 25.8 13.7 13.0 12.5 12.6 16.3 14.2 15.8 18.3 15.3 10.5 17.4 11.6 13.5 19.7 11.0 7.2 13.5 38.6 19.3 20.7 14.7 7.1 13.5 15.5 9.5 9.8 15.2 11.7 14.0 13.1 14.2 13.1 12.9 46.4 21.5 18.9 14.2 9.3 21.0 14.7 7.1 13.9 24.3 14.6 16.3 17.0 16.0 21.7 10.3 9.0 10.0 10.5 13.4 13.8 8.0 23.5 18.8 5.5 8.7 8.5 11.9 10.1 13.8 18.4 23.3 15.2 16.9 18.3 11.2 10.5 17.8 16.1 11.3 63.6 14.3 14.3 10.9 8.1 10.3 14.4 13.0 14.2 17.8 9.1 14.8 36.4 21.6 21.0 11.2 24.9 20.1 6.4 16.5 9.2 11.4 28.0 10.3 11.9 13.0 12.1 16.2 7.9 7.1 11.9 21.6 9.1 5.9 11.9 16.9 20.9 9.1 32.3 27.5 17.4 18.1 11.2 20.4 16.5 17.5 10.0 8.8 9.4 13.8 10.5 10.5 10.3 6.4 11.2 9.0 6.8 6.3 9.9 4.7 13.4 7.8 4.3 11.3 8.0 11.7 14.0 13.0 12.5 11.0 7.2 14.7 7.1 11.7 13.9 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 244.3" "Cell line enriched" "Detected in some" 65 "THP-1: 193.2" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 3.2;neutrophil: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;monocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015409, HPA066836" Enhanced "Secreted to blood" 59000 "CAB015409: AB_831596, HPA066836: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 1.5 0.3 0.1 0.3 0.1 244.3 1.6 0.2 0.6 0.3 0.6 0.7 0.0 0.3 0.3 0.7 0.5 0.6 0.8 31.2 0.0 0.0 0.3 1.5 17.8 1.6 0.0 0.0 0.3 1.8 0.3 0.4 4.7 0.5 1.4 0.3 1.0 0.7 0.3 1.1 2.1 0.5 0.5 0.0 22.5 0.5 0.3 0.0 23.0 2.3 0.9 0.3 1.0 0.2 0.0 0.0 6.9 3.2 0.0 0.5 11.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 11.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.5 0.0 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810092-225845563 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4;liver: 265.0" "Cell line enhanced" "Detected in many" "ASC diff: 153.8;SiHa: 73.1" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 6.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced 83000 "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favourable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favourable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 39.5 156.4 16.8 5.7 20.1 3.4 31.3 8.3 25.1 31.3 12.6 28.7 15.3 16.6 21.8 15.7 24.9 26.2 17.8 11.5 16.3 11.2 36.8 265.0 24.1 6.9 17.1 14.5 45.6 85.0 39.5 14.0 5.4 23.6 25.9 8.4 27.3 26.3 21.3 16.4 8.8 9.6 18.6 10.7 8.3 12.1 22.7 12.6 3.6 24.9 15.6 14.9 20.9 32.3 0.5 2.2 0.5 6.6 1.4 1.3 2.3 4.4 42.3 1.6 15.6 153.8 16.0 3.4 5.1 6.4 3.7 5.2 8.7 45.0 0.1 19.3 19.2 4.9 4.6 2.4 1.5 0.9 8.0 3.1 17.9 48.8 16.7 1.9 1.8 15.0 5.6 10.5 1.0 2.7 2.2 3.9 6.6 5.1 1.9 3.6 9.1 11.9 4.1 2.0 12.8 11.1 27.9 14.6 1.9 73.1 26.2 6.7 19.4 5.7 8.1 6.3 5.1 8.5 8.1 1.3 6.7 0.5 9.5 2.1 8.3 0.0 6.6 0.2 0.5 1.9 0.9 0.3 0.9 0.5 1.5 0.5 1.3 1.0 0.5 1.4 0.8 2.2 0.7 2.3 16.8 20.1 8.3 25.1 16.3 11.2 17.1 14.5 23.6 12.6 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122814-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 116.7" "Cell line enhanced" "Detected in some" "BJ: 8.3;CACO-2: 7.1;fHDF/TERT166: 7.4;Hep G2: 32.8;HHSteC: 6.8;SH-SY5Y: 16.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 16000000000 "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favourable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavourable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 8.1 3.7 0.3 2.9 0.7 0.0 5.4 0.4 0.8 20.3 5.9 0.6 7.6 4.5 12.6 21.4 4.5 9.9 10.0 18.4 0.5 0.5 2.3 116.7 4.9 1.6 0.5 0.7 18.2 3.0 0.0 1.7 3.6 1.0 18.1 0.7 6.9 2.0 6.1 2.6 7.8 7.6 11.7 0.6 1.3 3.2 9.5 0.6 0.6 3.1 5.6 1.8 7.8 10.3 0.0 0.0 0.0 0.0 0.9 1.0 0.3 0.0 0.0 1.4 0.2 4.8 4.9 0.0 8.3 6.6 0.5 0.2 7.1 0.0 0.0 0.3 7.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 32.8 6.8 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.6 16.2 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.3 0.3 0.7 0.4 0.8 0.5 0.5 0.5 0.7 1.0 0.6 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186265945-186288806 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 88.9" "Cell line enriched" "Detected in some" 11 "Hep G2: 13.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039808 Approved Vesicles "Secreted to blood" 4400000000 Vesicles "HPA039808: " "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favourable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 2.7 0.1 0.1 5.5 0.2 0.3 0.1 0.1 4.8 0.1 0.1 0.1 10.2 88.9 2.8 0.1 0.1 0.1 0.1 19.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.1 6.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402140-177409576 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "liver: 180.1" "Cell line enhanced" "Detected in some" "HDLM-2: 8.6;MCF7: 10.9;PC-3: 8.1;SH-SY5Y: 5.5;U-937: 5.6" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 2.5;eosinophil: 6.9" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003825 Approved "Secreted to blood" 1040000 6600000000 "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favourable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.2 180.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 1.0 6.9 2.5 0.7 0.3 1.0 0.8 2.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 1.3 0.0 0.4 0.0 1.4 0.7 0.4 0.0 8.6 1.8 1.3 0.3 0.9 0.2 0.7 3.0 0.2 1.3 0.1 0.4 0.2 0.4 3.2 0.0 10.9 0.1 2.6 0.0 8.1 0.6 0.2 1.8 1.1 0.0 2.5 5.5 0.3 1.0 0.7 0.4 0.0 0.0 0.2 1.1 0.0 0.3 0.5 0.0 0.1 0.1 5.6 0.6 0.0 2.5 6.9 0.3 0.1 0.2 0.5 0.3 0.2 0.1 0.2 0.0 0.1 0.9 0.7 0.9 1.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719180-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 593 "liver: 324.8" "Cell line enriched" "Detected in some" 21 "Hep G2: 76.5" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016780, CAB018650, HPA051476, HPA054698" Enhanced "Secreted to blood" 107500000000 43000000000 "CAB016780: , CAB018650: AB_2246689, HPA051476: , HPA054698: " "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavourable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 324.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 76.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "liver: 68.0" "Group enriched" "Detected in some" 9 "CACO-2: 16.2;Hep G2: 10.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "gdT-cell: 1.7;MAIT T-cell: 1.2;memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" 3600000 1500000000 Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 68.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530758-139563458 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2334 "liver: 233.6" "Cell line enhanced" "Detected in some" "HL-60: 1.7;RH-30: 1.9;SiHa: 1.5;U-698: 1.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" 11000000000 "prognostic favourable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.0" "Cell line enhanced" "Detected in some" "ASC diff: 47.0;ASC TERT1: 49.9;BJ hTERT+: 39.4;TIME: 19.7;U-138 MG: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059739 Uncertain "Secreted to blood" 34000000 "HPA059739: " "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 19.8 0.7 2.6 3.2 1.2 0.0 7.5 0.6 3.7 17.6 4.5 0.4 4.0 0.1 30.0 13.7 4.1 5.1 14.9 5.2 3.1 0.9 2.0 0.9 4.7 0.8 2.6 1.2 4.1 2.3 0.5 1.0 17.0 1.9 4.1 1.5 2.4 5.3 3.9 8.1 2.9 1.4 17.9 2.2 0.9 1.7 9.8 3.4 0.0 3.5 9.0 0.8 12.4 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 49.9 0.0 19.2 39.4 4.0 6.1 0.0 0.0 0.0 0.1 7.3 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 16.1 0.3 6.7 1.2 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 2.0 0.0 0.0 19.7 40.1 0.8 9.7 0.0 0.0 0.0 0.0 9.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.2 0.6 3.7 3.1 0.9 2.6 1.2 1.9 3.4 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868592-90883458 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "liver: 118.4;placenta: 158.9;salivary gland: 337.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009499 Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 41000 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095" "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 8.3 3.3 3.0 7.5 3.6 16.6 5.9 5.0 4.4 4.1 6.6 2.8 3.5 5.7 4.9 10.8 4.7 4.4 3.9 6.9 3.1 1.8 6.4 118.4 9.5 3.1 2.8 2.7 4.2 22.5 3.8 7.2 158.9 3.5 9.3 2.2 3.0 337.9 4.7 8.7 9.0 5.9 3.1 3.0 8.2 6.0 5.3 2.9 4.8 8.9 5.5 4.1 4.4 4.3 1.5 3.3 10.3 3.3 3.1 1.9 2.0 14.1 8.6 1.9 8.7 14.3 9.2 22.2 17.8 13.6 7.4 5.2 12.6 15.5 0.5 45.9 12.9 25.5 3.9 9.2 1.6 40.7 10.1 24.8 15.5 16.5 7.6 3.4 40.9 10.4 10.4 8.4 3.8 23.6 18.9 2.5 4.9 9.7 1.3 11.2 6.2 2.5 2.2 7.5 3.2 11.5 10.8 3.9 2.6 15.1 8.2 12.6 2.9 9.1 34.7 8.3 17.8 12.7 26.1 4.4 25.1 1.1 15.9 11.2 16.8 7.5 3.3 10.3 1.9 1.1 1.4 1.5 1.2 1.2 2.1 1.0 0.6 0.8 7.4 3.1 0.7 3.3 0.9 2.0 3.0 3.6 5.0 4.4 3.1 1.8 2.8 2.7 3.5 2.9 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102648-55110252 "Enzymes, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 92.3;intestine: 31.0;lymphoid tissue: 40.9" "Cell line enriched" "Detected in some" 4 "HL-60: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "gdT-cell: 92.3;MAIT T-cell: 90.8;memory CD4 T-cell: 25.4;memory CD8 T-cell: 89.3;naive CD8 T-cell: 50.5;NK-cell: 61.9" "Group enriched" "Detected in many" 38 "NK-cells: 61.9;T-cells: 92.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054134 Approved "Secreted to blood" "HPA054134: " "prognostic favourable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favourable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavourable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 4.3 1.8 1.1 16.3 1.2 10.0 2.5 0.7 0.8 3.9 12.5 0.9 1.3 10.3 5.2 2.9 2.9 2.9 9.6 4.5 1.1 1.1 4.6 5.2 11.8 20.3 1.7 0.9 3.0 5.8 0.0 1.9 5.8 1.5 3.4 6.3 4.5 5.1 1.3 2.6 1.2 31.0 2.5 2.6 40.9 3.9 1.1 0.6 1.9 3.1 4.2 11.1 6.6 2.9 0.2 0.2 2.0 0.3 61.9 92.3 52.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 92.3 0.2 90.8 0.2 25.4 89.3 0.2 0.1 5.2 50.5 2.0 61.9 0.3 0.2 2.9 52.0 1.1 1.2 0.7 0.8 1.1 1.1 1.7 0.9 1.5 0.6 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "blood: 298.5" "Cell line enriched" "Detected in some" 5 "HMC-1: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 298.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 298.5" "CAB000376, HPA003418" Enhanced "Secreted to blood" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favourable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favourable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 6.4 0.7 0.8 8.0 1.1 26.4 3.2 0.7 0.7 1.6 3.0 0.5 1.3 0.8 3.9 1.5 4.0 1.0 3.1 4.8 0.7 2.4 2.1 5.7 21.7 16.7 1.1 0.0 1.4 0.7 0.0 1.0 7.5 0.8 2.6 0.9 4.0 2.7 2.3 3.5 0.6 2.9 1.8 1.5 33.0 3.5 0.9 0.4 6.1 4.4 5.3 16.8 6.0 1.5 0.2 298.5 2.0 0.2 19.9 60.5 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.7 2.9 0.3 0.1 0.2 60.5 0.1 0.7 0.2 4.6 28.4 0.2 0.1 1.4 28.7 2.0 19.9 0.2 298.5 0.1 53.6 0.8 1.1 0.7 0.7 0.7 2.4 1.1 0.0 0.8 0.4 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "blood: 134.9" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPMI-8226: 2.0;THP-1: 1.4;U-266/70: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 134.9;memory CD4 T-cell: 41.8;memory CD8 T-cell: 109.7;naive CD8 T-cell: 102.7" "Lineage enriched" "Detected in many" 8 "T-cells: 134.9" "Low region specificity" "Detected in all" HPA029200 Enhanced "Secreted to blood" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favourable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavourable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.6 3.1 1.1 5.0 1.2 16.5 3.6 0.5 1.0 1.9 3.1 0.4 0.2 0.9 1.0 2.7 2.6 1.8 8.1 4.8 1.0 1.1 1.7 3.6 16.4 11.5 2.6 1.3 3.0 1.1 0.0 3.7 1.6 1.2 4.5 1.1 5.1 5.4 4.2 4.5 0.8 2.2 2.0 3.1 22.6 2.5 2.5 0.7 0.2 2.5 3.4 6.4 5.1 1.9 0.4 3.2 1.8 0.3 17.6 134.9 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.4 0.9 1.8 0.2 0.1 134.9 0.2 2.4 0.4 41.8 109.7 0.2 0.2 13.9 102.7 1.5 17.6 0.3 3.2 0.3 82.9 1.1 1.2 0.5 1.0 1.0 1.1 2.6 1.3 1.2 0.7 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024253-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 95.8;lymphoid tissue: 37.3" "Cell line enhanced" "Detected in single" "U-2197: 1.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "MAIT T-cell: 95.8;memory CD8 T-cell: 59.0" "Group enriched" "Detected in many" 191 "NK-cells: 56.9;T-cells: 95.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063181 Enhanced "Secreted to blood" "HPA063181: " "prognostic favourable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.5 1.6 0.6 10.5 0.6 3.6 3.1 0.5 0.5 4.1 3.7 0.2 1.7 0.4 3.2 2.6 2.8 1.8 7.4 1.6 0.6 0.7 4.3 4.1 10.2 37.3 0.7 0.2 2.1 1.5 0.0 1.0 0.9 0.5 6.6 1.9 2.9 5.7 2.1 0.8 0.8 7.4 0.8 1.6 36.4 2.4 2.1 0.3 3.3 3.1 2.7 28.2 4.9 2.6 0.0 0.1 0.4 0.1 56.9 95.8 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 21.1 0.1 95.8 0.0 13.2 59.0 0.0 0.0 0.6 10.5 0.4 56.9 0.1 0.1 0.8 9.9 0.6 0.6 0.5 0.5 0.6 0.7 0.7 0.2 0.5 0.3 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 79.2;lymphoid tissue: 28.6" "Cell line enhanced" "Detected in some" "EFO-21: 5.2;HDLM-2: 4.2;HMC-1: 5.3;MOLT-4: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "gdT-cell: 79.2" "Group enriched" "Detected in many" 31 "NK-cells: 22.7;T-cells: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015624 Enhanced "Secreted to blood" "HPA015624: " "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favourable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favourable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 1.8 1.0 0.7 13.6 0.9 15.6 1.0 4.3 1.4 1.0 3.5 0.2 0.1 1.8 1.0 2.9 2.0 1.1 4.7 1.6 0.7 0.6 1.1 2.6 4.8 15.1 0.7 0.4 0.8 0.4 0.0 0.9 1.6 0.5 1.7 0.1 1.5 12.0 0.3 0.8 0.7 5.1 0.5 1.1 21.1 3.0 1.5 0.4 28.6 1.4 1.1 10.9 1.1 1.2 0.4 0.4 1.6 0.2 22.7 79.2 27.0 0.1 0.7 0.1 0.3 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.6 0.2 0.1 5.2 0.0 0.1 0.0 0.0 0.0 4.2 0.4 0.0 0.6 0.2 0.6 0.4 5.3 0.2 0.0 0.1 0.0 0.1 1.6 0.3 0.0 1.2 3.4 1.4 0.9 0.8 0.3 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.8 0.9 0.0 1.1 0.4 1.1 0.3 0.8 0.3 0.8 0.1 0.1 79.2 0.2 49.8 0.1 26.4 63.6 0.1 0.4 25.8 53.1 1.6 22.7 0.2 0.4 12.2 27.0 0.7 0.9 4.3 1.4 0.7 0.6 0.7 0.4 0.5 0.4 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 135.4" "Cell line enriched" "Detected in some" 6 "RPTEC TERT1: 33.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" 20206666667 3200000000 "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.6 0.6 0.3 0.0 0.4 26.4 0.4 0.0 0.0 20.9 135.4 0.2 0.0 0.0 0.0 0.8 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 33.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699008-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 116.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 44.8;HHSteC: 35.1;HL-60: 19.6;hTEC/SVTERT24-B: 22.0;Karpas-707: 60.7;U-87 MG: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "basophil: 33.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 33.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved Approved Centrosome,Cytosol "Secreted to blood" Cytosol Centrosome "CAB010333: AB_647965, HPA040360: , HPA044088: " "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavourable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 6.2 10.6 1.4 2.9 1.2 4.6 4.8 0.5 4.5 5.1 4.0 0.4 2.9 1.5 5.2 3.1 2.9 4.0 7.1 9.3 3.6 1.3 7.3 27.5 15.8 2.0 1.3 1.4 3.2 1.4 1.6 4.3 116.9 1.9 10.8 1.9 2.0 2.2 3.2 1.4 0.9 1.8 15.1 6.0 6.6 2.3 2.0 0.9 0.5 5.3 1.4 1.4 10.5 21.5 0.0 2.0 33.5 7.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 5.5 44.8 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 35.1 19.6 0.1 10.6 0.0 22.0 0.0 0.5 0.0 60.7 0.1 0.0 0.0 13.6 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 16.1 4.1 0.0 33.5 6.6 1.6 0.0 7.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.3 0.0 6.7 0.4 0.0 1.5 1.4 1.2 0.5 4.5 3.6 1.3 1.3 1.4 1.9 0.9 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441887-3449495 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 141 "liver: 128.0" "Cell line enriched" "Detected in some" 8 "Hep G2: 10.7" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058279, HPA059076" Enhanced "Secreted to blood" 7586667 11000000000 "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavourable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 128.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.2 1.2 0.7 0.4 0.1 0.0 0.0 0.6 1.1 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.7 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 HP ENSG00000257017 Haptoglobin P00738 16 72054592-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "liver: 1156.9" "Group enriched" "Detected in some" 5 "Hep G2: 64.7;HSkMC: 37.1" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "classical monocyte: 20.0;eosinophil: 30.9" "Group enriched" "Detected in many" 7 "granulocytes: 30.9;monocytes: 20.0" "CAB003787, HPA047750" Enhanced Approved Vesicles "Secreted to blood" 181000000 140000000000 Vesicles "CAB003787: , HPA047750: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavourable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 9.8 0.0 0.3 0.4 0.3 4.4 0.3 0.3 0.3 1.5 0.4 0.3 0.3 0.0 0.3 0.5 0.3 1.1 0.3 3.0 0.3 0.0 0.4 1156.9 1.4 0.4 0.3 0.3 0.3 0.5 0.0 0.5 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 1.4 0.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.5 0.0 3.5 30.9 20.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.3 0.0 64.7 0.1 9.2 1.7 37.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.5 0.1 0.7 0.0 0.3 6.9 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.1 1.4 0.0 0.2 0.0 0.0 1.2 0.0 4.4 0.0 3.6 0.0 2.6 20.0 30.9 0.0 0.8 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 5.8 0.0 0.9 0.0 0.0 5.0 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066571 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 55.4;liver: 146.5;pancreas: 80.1" "Group enriched" "Detected in some" 9 "EFO-21: 19.4;Hep G2: 27.5;T-47d: 13.4" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.2;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 5 "T-cells: 1.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved 1000000 "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favourable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 0.2 0.0 0.3 0.1 0.5 0.0 3.2 0.4 1.1 0.3 0.3 0.2 8.4 0.2 1.1 10.7 0.1 1.9 3.2 0.7 0.6 0.3 55.4 146.5 4.9 0.1 0.9 0.2 0.4 80.1 2.6 3.2 0.2 0.4 5.3 0.0 0.4 4.1 8.5 8.5 0.0 0.2 0.1 0.9 0.3 6.9 0.8 0.3 0.1 4.3 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.1 0.0 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.1 0.1 0.0 0.1 13.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.6 0.2 0.5 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.5 0.4 1.1 0.6 0.3 0.9 0.2 0.4 0.3 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063224-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 151.4" "Cell line enriched" "Detected in some" 14 "Hep G2: 32.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA047750 Supported Approved Vesicles "Secreted to blood" 49000000000 77000000000 Vesicles "HPA047750: " "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 0.2 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 15.2 0.7 0.8 0.1 151.4 0.0 0.1 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 2.9 1.1 1.0 0.4 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 1.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.3 1.0 0.1 0.5 0.4 0.4 0.3 1.1 2.0 1.1 0.3 0.4 0.3 2.9 2.3 0.3 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122461525-122514908 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 198.9;ASC TERT1: 73.9;fHDF/TERT166: 67.4;HSkMC: 129.7;LHCN-M2: 98.6;U-87 MG: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.4;memory CD4 T-cell: 1.6" "Group enriched" "Detected in many" 20 "monocytes: 2.4;T-cells: 1.6" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" 24800000 2600000 "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (5.62e-6)" 40.8 21.8 64.5 9.1 79.0 0.5 48.2 16.2 62.8 50.4 19.3 60.8 7.2 5.6 47.6 67.0 15.6 19.5 78.7 28.7 50.8 35.4 34.7 60.4 14.6 9.1 62.7 32.5 111.3 14.5 37.6 26.9 114.1 41.9 19.5 14.0 20.7 19.3 31.5 7.5 29.6 9.3 40.5 46.5 10.5 12.9 9.8 49.5 1.7 13.3 8.5 7.1 41.5 27.3 0.0 0.0 0.0 2.4 0.0 1.6 0.7 0.0 3.4 1.5 0.4 198.9 73.9 0.0 8.5 15.6 3.5 1.9 0.0 0.0 0.0 2.3 67.4 1.0 0.6 9.7 0.5 0.0 0.3 0.0 5.7 0.0 10.1 0.0 0.0 129.7 35.7 2.0 16.6 16.3 0.0 0.1 98.6 1.7 0.0 0.0 1.6 5.4 0.0 0.1 0.0 22.5 0.1 0.1 0.3 21.4 0.0 9.2 0.6 0.0 10.7 25.1 0.3 11.3 7.2 0.0 0.0 0.0 81.4 0.0 11.7 0.0 2.4 0.0 0.6 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 64.5 79.0 16.2 54.6 50.8 35.4 62.7 32.5 41.9 49.5 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529377-74533348 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria Mitochondria "CAB004004: AB_326421, HPA006602: , HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 16.4 12.7 10.6 14.9 11.3 18.9 12.9 10.7 17.7 12.3 12.8 12.6 9.7 12.6 12.9 6.9 10.7 10.6 9.0 12.9 11.6 8.7 13.1 11.4 11.3 13.2 10.8 11.9 18.7 12.9 10.5 9.0 10.4 13.5 11.6 5.5 10.2 13.1 9.2 17.6 9.0 12.6 11.8 9.1 17.3 11.8 13.9 12.6 12.2 16.8 12.6 9.3 10.4 15.2 12.9 9.4 5.9 8.1 5.5 7.8 7.0 7.9 4.9 5.7 4.9 7.9 3.2 15.2 6.9 3.6 4.2 2.4 9.1 3.5 7.2 5.4 3.9 9.0 6.7 7.9 1.1 16.2 13.4 14.4 4.7 8.0 7.4 6.7 10.6 3.8 5.3 7.9 6.7 5.2 18.9 10.7 3.1 5.2 12.4 14.2 4.7 14.2 8.5 16.1 7.9 3.4 3.2 6.6 7.9 3.7 8.5 13.2 3.9 6.6 3.7 7.3 9.0 14.7 15.4 13.1 4.3 4.7 6.3 10.7 5.8 5.9 8.1 4.8 7.3 6.2 7.8 12.9 7.3 6.2 9.4 11.6 6.3 6.4 3.2 5.5 4.7 6.6 7.4 7.0 10.6 11.3 10.7 17.7 11.6 8.7 10.8 11.9 13.5 12.6 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269765-8307111 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.9" "Cell line enriched" "Detected in some" 5 "U-2197: 62.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 9 "basal ganglia: 8.2" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in female reproductive system" Vesicles "HPA021187: AB_1851311, HPA063810: " "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavourable (1.29e-4)" "unprognostic (1.34e-2)" 23.7 1.8 0.6 7.3 8.2 5.3 35.6 0.7 0.9 12.3 9.4 0.8 5.4 3.7 19.6 26.6 14.4 7.9 19.8 57.9 0.7 0.3 1.7 1.6 15.4 4.3 0.8 0.9 30.7 2.8 0.0 5.1 9.6 0.9 15.4 2.0 8.6 6.6 3.0 12.9 9.0 6.7 50.1 0.8 1.8 6.8 7.2 0.6 1.3 9.3 11.6 3.0 28.7 12.7 0.0 0.4 1.3 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 2.0 3.8 0.1 0.8 0.0 0.9 0.2 0.0 0.0 0.0 4.7 2.1 0.0 0.4 0.0 0.3 0.0 0.7 0.4 4.9 0.0 2.1 0.0 0.2 0.4 0.0 1.4 0.0 3.3 0.1 0.0 3.5 0.0 0.0 12.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 5.5 0.1 8.9 0.1 0.0 0.0 0.3 2.7 0.5 1.6 62.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.1 0.6 8.2 0.7 0.9 0.7 0.3 0.8 0.9 0.9 0.6 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974164-38988662 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "placenta: 55.2" "Cell line enriched" "Detected in single" 134 "BEWO: 71.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in some" "hippocampal formation: 2.3" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" "HPA045402: " "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 2.6 1.1 0.2 0.3 0.2 3.4 0.9 0.2 0.4 1.2 0.5 0.2 1.9 0.0 2.3 0.5 0.5 0.1 0.2 0.2 0.2 0.0 0.2 0.2 4.3 1.0 0.2 0.2 0.4 0.3 0.4 0.5 55.2 0.4 0.5 0.3 1.8 0.8 0.5 0.6 0.4 0.6 0.3 1.8 2.5 0.1 0.4 0.2 0.2 0.6 0.2 0.8 0.5 0.9 3.1 2.2 2.5 1.0 1.0 1.7 0.0 0.1 0.1 0.1 0.1 0.3 0.2 71.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.1 0.5 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.1 1.5 0.8 2.3 1.4 0.7 1.7 1.5 1.3 1.2 0.6 3.1 1.3 1.4 2.5 1.0 1.0 2.2 1.4 0.0 0.2 0.2 0.2 0.4 0.2 0.0 0.2 0.2 0.4 0.2 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058308 Approved "HPA058308: " "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavourable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favourable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 9.1 16.6 25.4 11.6 27.8 8.8 15.4 28.4 18.5 10.0 11.3 11.7 12.8 12.1 9.6 25.6 8.4 7.7 5.1 20.4 21.7 17.4 16.2 11.9 10.7 11.2 16.1 12.1 14.0 23.8 7.2 18.2 8.7 11.4 11.2 8.3 17.4 13.6 12.0 39.8 10.1 10.3 9.3 13.2 7.6 10.8 13.8 12.6 17.6 10.0 13.3 10.8 6.8 7.5 16.4 20.0 14.8 1.7 16.9 21.7 7.8 10.7 15.7 41.7 12.4 5.6 3.8 7.8 14.3 3.2 6.0 4.6 12.0 8.3 11.2 10.0 6.1 12.5 14.3 10.8 9.1 15.1 30.3 13.3 23.5 15.3 6.0 17.3 12.8 3.2 9.7 3.5 7.7 6.4 21.2 13.6 5.7 13.4 21.8 24.9 8.5 13.8 17.2 36.0 10.9 20.4 13.3 11.5 13.2 16.6 8.3 14.2 18.9 17.8 3.0 14.1 14.0 10.9 22.8 12.4 25.7 19.6 18.5 11.8 13.8 9.0 1.7 14.8 15.6 1.6 14.5 16.4 14.0 15.5 4.0 15.0 17.7 21.7 0.3 16.9 1.6 20.0 16.6 7.8 25.4 27.8 28.4 18.5 21.7 17.4 16.1 12.1 11.4 12.6 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110663051-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavourable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 12.4 12.4 7.9 7.3 10.8 2.9 11.8 5.4 9.1 12.4 11.1 5.7 10.6 5.2 23.8 10.4 8.0 11.5 5.8 8.6 7.1 6.0 23.8 17.7 7.4 4.4 5.7 6.1 14.4 10.0 13.4 15.7 8.0 6.3 13.8 5.8 31.6 11.6 15.8 18.6 7.5 10.9 14.4 5.6 5.3 9.8 9.0 5.6 8.2 16.7 8.3 9.5 11.0 9.2 18.1 11.7 5.8 8.4 24.3 15.1 5.1 7.8 4.7 2.8 11.7 7.6 7.7 5.0 5.4 5.5 3.6 3.8 2.3 9.2 12.9 14.9 4.7 4.4 3.0 10.9 6.0 8.0 3.1 4.4 18.7 6.4 11.6 8.1 0.5 13.4 14.5 1.5 10.1 4.7 14.1 10.0 2.7 5.4 10.8 9.1 2.8 7.4 2.3 23.5 6.7 13.2 3.3 3.3 10.4 2.3 11.1 30.0 4.5 4.7 3.0 5.6 5.8 5.6 6.5 5.7 1.5 7.9 6.1 3.8 29.3 5.8 5.1 1.6 6.4 6.4 11.4 16.3 10.8 7.2 9.4 18.1 15.1 10.5 0.2 24.3 8.4 11.7 6.4 5.1 7.9 10.8 5.4 9.1 7.1 6.0 5.7 6.1 6.3 5.6 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819148-50823787 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "pancreas: 742.6;salivary gland: 473.0" "Cell line enriched" "Detected in some" 23 "RPMI-8226: 28.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 20.0;pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 10.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 14 "B-cells: 10.9" "Secreted to digestive system" 4300000 "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.2 2.5 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.8 0.1 0.1 0.1 0.1 0.1 0.1 742.6 0.0 0.1 0.1 0.1 0.2 1.9 0.1 473.0 0.1 0.1 1.8 0.6 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.2 0.2 0.2 0.1 0.1 10.9 0.7 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 10.9 0.0 0.0 0.2 3.8 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 78.6;lymphoid tissue: 58.6;tongue: 136.3" "Group enriched" "Detected in some" 6 "CAPAN-2: 52.5;HaCaT: 79.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.7" "Not detected" "Not detected" "Secreted in other tissues" 670000 "prognostic favourable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavourable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 1.5 0.5 0.2 1.7 0.3 0.3 2.4 0.7 0.4 20.8 0.9 0.3 0.5 0.2 2.9 0.8 78.6 7.8 36.0 0.7 0.2 0.5 0.2 0.3 4.3 0.2 0.2 0.3 7.2 0.2 0.0 0.2 0.8 0.6 1.6 0.4 0.3 11.0 0.6 0.4 17.7 0.4 0.4 0.4 0.2 0.5 1.6 0.2 1.0 0.3 136.3 58.6 0.5 33.4 0.4 0.5 2.1 0.4 0.4 0.3 0.1 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 52.5 0.0 2.9 0.0 79.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.3 0.2 0.3 0.2 0.3 0.2 0.1 0.4 0.3 0.3 2.1 0.4 0.4 0.5 0.3 0.1 0.2 0.3 0.7 0.4 0.2 0.5 0.2 0.3 0.6 0.2 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.4;lymphoid tissue: 88.5;salivary gland: 96.5" "Group enriched" "Detected in some" 4 "EFO-21: 9.4;HaCaT: 29.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "pons and medulla: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" 320000 "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favourable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 5.5 0.0 0.2 1.1 0.2 0.0 4.9 0.2 0.6 24.5 1.7 2.0 0.4 0.0 5.1 2.7 103.4 9.7 61.8 0.4 0.9 0.0 0.2 0.6 12.3 0.2 0.2 0.2 2.3 25.0 0.0 2.1 0.4 10.7 18.8 0.0 5.1 96.5 1.6 0.3 49.8 0.6 0.3 0.2 0.2 18.7 7.7 0.2 0.9 0.2 65.2 88.5 0.7 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 9.4 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.9 0.0 0.2 0.2 10.7 0.2 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix, uterine: 27.6;esophagus: 53.9;lymphoid tissue: 24.7;tongue: 33.3;vagina: 24.8" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;HaCaT: 2.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favourable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 27.6 2.0 0.0 0.0 3.6 1.2 0.2 53.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.7 0.0 16.6 0.0 0.0 0.4 4.3 0.1 0.2 0.0 0.4 0.5 0.0 0.2 0.0 33.3 24.7 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51056206-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 100.5" "Cell line enriched" "Detected in some" 11 "HaCaT: 20.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 42.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" "HPA062136: " "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.2 15.7 0.4 0.2 0.1 0.2 0.3 0.1 100.5 0.2 0.9 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.4 1.7 0.0 0.5 0.1 0.2 0.1 0.0 0.3 12.4 0.1 1.2 2.1 0.4 0.1 0.1 0.1 0.2 6.1 0.1 0.1 0.1 17.9 12.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 20.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.1 KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 14.2" "Cell line enhanced" "Detected in some" "HaCaT: 13.7;HEK 293: 3.9;U-266/84: 7.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026228 Uncertain "Secreted in other tissues" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" 0.2 0.0 0.4 0.2 1.2 0.1 2.7 2.1 0.9 3.8 0.6 1.8 0.4 0.9 1.2 0.8 0.3 1.1 0.6 0.5 0.1 0.1 0.5 0.4 0.3 0.9 0.4 0.0 0.3 0.0 0.7 0.4 1.1 0.7 0.3 14.2 1.0 0.0 0.3 0.4 0.8 0.7 0.1 0.6 0.2 3.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.7 0.7 0.1 0.9 0.6 0.6 0.7 0.2 0.0 0.0 0.2 1.7 2.1 0.8 0.6 0.3 13.7 0.2 0.3 0.0 0.5 3.9 0.3 1.0 0.0 0.2 0.3 0.3 0.4 0.4 0.5 0.6 0.2 0.3 0.5 0.0 1.2 0.2 0.8 0.8 1.5 0.2 0.1 0.8 0.0 0.7 0.1 0.0 0.3 1.2 0.4 0.6 0.0 0.0 0.2 0.6 0.9 0.2 3.6 7.1 0.5 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.7;salivary gland: 9.7" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 7.2" "Cancer enhanced" "Detected in some" "prostate cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 2.1 9.7 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell line enhanced" "Detected in many" "NB-4: 9.9" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA000764 Supported "Secreted in male reproductive system" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.8 4.9 0.5 0.3 0.2 0.2 0.6 0.7 1.8 0.2 0.0 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.4 0.3 0.3 0.4 0.0 1.4 1.9 0.3 1.8 1.2 9.9 1.1 0.0 0.9 0.0 2.8 0.0 1.6 0.9 1.5 0.3 1.3 1.3 1.2 0.4 0.8 1.3 1.9 4.8 1.6 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 115 "prostate: 447.4" "Group enriched" "Detected in some" 135 "BEWO: 21.9;NB-4: 18.5;RPMI-8226: 12.2;SH-SY5Y: 7.3;U-2197: 7.5" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 0.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 447.4 0.0 0.1 3.8 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "prostate: 79.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.2;HaCaT: 10.1;SK-BR-3: 6.5" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051839 Enhanced "Secreted in male reproductive system" "HPA051839: " "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.2 0.8 0.1 0.3 0.1 0.1 0.7 0.2 0.5 2.0 1.2 0.0 3.8 1.8 1.5 7.7 0.4 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.5 79.3 0.8 0.2 3.2 2.1 0.7 2.4 1.2 0.6 0.1 0.1 0.3 0.6 0.1 0.0 8.7 0.0 0.0 0.2 0.2 0.1 0.4 0.6 0.1 0.0 0.3 0.0 5.0 2.1 0.2 0.3 0.0 0.0 4.5 0.1 0.0 0.0 0.0 4.6 8.2 0.5 0.4 0.1 10.1 0.0 5.4 0.0 1.3 1.4 1.6 3.7 1.7 0.0 1.7 2.3 0.0 2.6 0.0 0.0 0.0 0.9 4.2 0.0 1.2 0.1 2.5 0.1 0.4 0.3 0.5 1.1 0.0 3.3 0.0 0.6 0.3 6.5 0.0 5.2 0.4 1.1 0.3 0.3 1.3 0.3 2.6 1.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.5 0.3 0.2 0.2 0.0 0.5 0.1 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skin 1: 69.2;tongue: 67.3" "Group enriched" "Detected in some" 40 "A-431: 85.3;HaCaT: 83.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014343, CAB025503, CAB026341" Enhanced "Secreted in other tissues" "CAB025503: , CAB026341: , HPA014343: AB_1852603" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavourable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavourable (3.85e-6)" 1.1 0.0 0.7 0.4 0.2 0.0 12.1 0.2 0.5 3.8 0.3 0.2 0.2 0.1 1.4 0.9 6.5 0.2 0.3 0.2 0.2 0.1 0.6 0.2 2.5 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.4 0.2 0.0 0.3 7.0 0.2 0.4 69.2 0.2 0.2 0.2 0.2 0.0 3.3 0.2 0.4 0.3 67.3 4.4 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 83.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 0.5 0.2 0.1 0.2 0.2 0.4 0.2 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.6;esophagus: 48.9" "Group enriched" "Detected in some" 14 "A-431: 68.4;CAPAN-2: 163.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 175.6" "Group enriched" "Detected in many" 8 "midbrain: 106.3;pons and medulla: 164.1;thalamus: 62.4" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" 6800000 Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavourable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavourable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavourable (1.27e-4)" 0.9 0.9 9.7 0.9 23.5 0.9 6.5 3.3 42.2 10.0 1.0 82.0 0.0 1.1 2.0 1.2 48.9 24.6 3.8 0.9 20.1 11.8 9.0 0.9 0.9 0.9 46.1 14.9 0.9 0.9 0.9 0.2 0.9 44.3 1.0 0.9 0.0 5.9 2.8 0.9 2.9 0.9 1.0 97.6 5.1 1.0 1.5 32.6 0.0 0.9 15.7 28.1 0.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.1 163.7 0.0 1.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.1 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 23.5 3.3 23.1 20.1 11.8 46.1 14.9 44.3 32.6 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976482-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 29.1;skin 1: 77.5;tongue: 90.2" "Group enriched" "Detected in some" 6 "CAPAN-2: 6.6;HaCaT: 25.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" 960000 "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 2.1 0.3 5.4 0.3 4.3 0.4 5.6 0.5 11.3 5.4 0.3 0.0 0.0 0.5 0.7 0.3 29.1 7.8 3.3 0.2 4.8 0.5 2.6 0.2 1.6 0.3 0.3 3.5 1.0 0.2 0.2 0.1 0.5 4.2 0.3 0.2 0.0 7.4 0.3 0.6 77.5 0.3 0.4 0.3 0.5 0.4 0.3 0.0 0.0 0.4 90.2 15.3 0.2 9.0 1.1 0.4 1.3 0.8 2.1 1.0 0.6 2.6 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 6.6 0.0 1.0 0.0 25.9 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 1.3 0.8 0.4 0.4 0.4 0.7 0.6 0.6 0.4 0.4 1.1 1.0 0.9 0.9 2.1 0.4 0.4 0.7 0.6 5.4 4.3 0.5 11.3 4.8 0.5 0.3 3.5 4.2 0.0 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.6;skin 1: 40.4;tongue: 46.9" "Group enriched" "Detected in some" 7 "A-431: 31.5;CAPAN-2: 41.3;HaCaT: 30.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "hippocampal formation: 39.6" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" 950000 Vesicles "CAB019393: , HPA035761: " "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavourable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavourable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavourable (6.17e-4)" 1.6 0.0 0.1 0.4 0.1 0.0 4.5 1.0 0.3 8.1 0.7 0.1 0.1 0.0 1.1 0.7 43.6 6.7 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.4 0.6 0.3 0.0 0.3 6.0 0.1 0.3 40.4 0.1 0.1 0.6 0.3 0.0 0.7 0.1 0.5 0.3 46.9 11.1 0.3 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.6 41.3 0.0 0.8 0.0 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.3 0.1 0.0 0.1 0.1 0.6 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51003111-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 37.6" "Group enriched" "Detected in some" 27 "HaCaT: 1.2;HBEC3-KT: 4.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025049 Enhanced "Secreted to digestive system" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 37.6 3.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 102.9" "Cell line enhanced" "Detected in some" "NTERA-2: 7.1;SCLC-21H: 4.9;SK-MEL-30: 2.1;U-937: 2.4" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 7 "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 28860000000 4900000000 "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.3 0.3 0.8 0.3 1.2 0.0 0.3 0.7 0.5 0.3 0.4 0.3 0.3 0.7 0.4 0.4 0.3 0.2 0.7 0.5 0.6 0.5 1.3 102.9 0.3 0.3 0.5 0.5 0.3 1.3 0.5 1.0 0.4 0.4 0.3 0.3 0.5 0.3 0.3 0.5 0.1 0.6 0.3 0.3 0.5 0.0 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 7.1 0.0 0.1 0.0 0.2 1.3 0.0 4.9 0.4 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.2 0.7 0.5 0.6 0.5 0.5 0.5 0.4 0.3 LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121800-63142061 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA036361: AB_10672244, HPA036362: AB_10670798" "unprognostic (6.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.10e-2)" "unprognostic (8.08e-2)" "unprognostic (6.25e-2)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (6.22e-3)" "unprognostic (5.16e-3)" "unprognostic (6.28e-2)" "unprognostic (3.24e-1)" "unprognostic (8.64e-2)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" 26.5 22.7 9.2 13.1 12.2 31.5 9.3 7.3 9.1 6.8 11.4 6.3 4.0 12.5 7.0 6.9 9.8 5.7 9.2 24.9 7.9 6.1 20.5 38.3 18.8 12.9 8.5 6.1 7.2 9.3 6.7 10.4 7.4 9.5 7.6 10.4 5.8 9.3 4.7 37.3 10.1 19.6 8.1 8.0 21.6 8.3 13.2 9.8 8.3 8.4 11.1 9.0 11.5 12.8 3.3 10.4 5.8 8.9 2.3 3.1 2.0 21.4 13.5 3.8 2.6 19.5 10.5 3.2 9.4 14.5 16.2 30.2 3.4 13.8 2.8 11.6 13.6 6.0 13.1 6.1 20.3 19.7 3.2 5.5 4.6 8.4 18.2 5.0 9.6 14.2 13.0 16.6 13.7 16.6 5.2 8.2 27.3 8.1 3.8 6.0 5.8 4.2 2.8 9.9 6.5 8.7 33.6 3.5 1.6 6.8 7.7 20.2 5.8 8.2 29.7 21.8 17.1 9.8 11.8 8.6 7.5 0.7 16.7 14.1 10.0 3.6 8.8 4.6 1.3 8.9 2.0 3.3 1.1 1.0 10.4 2.9 1.0 1.6 5.8 2.3 7.6 0.9 3.1 2.0 9.2 12.2 7.3 9.1 7.9 6.1 8.5 6.1 9.5 9.8 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 78.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 15.8 78.3 16.4 12.8 19.8 12.5 13.9 16.1 22.8 11.3 13.6 15.8 13.3 13.7 10.5 13.8 12.7 12.7 15.7 27.3 15.4 15.3 19.9 49.6 10.3 14.5 17.7 14.9 15.5 17.7 17.6 16.8 16.6 16.2 11.7 8.5 12.7 18.5 14.7 38.0 14.7 13.9 11.5 12.7 15.5 13.5 9.8 13.3 13.8 21.2 15.3 11.8 14.7 12.5 6.7 6.5 6.0 6.2 4.0 7.2 3.0 23.0 23.9 7.9 25.3 9.4 6.7 24.7 14.7 11.7 15.9 19.5 20.4 8.3 29.0 20.6 15.4 9.8 20.4 17.8 7.7 17.1 16.8 16.0 20.9 26.7 43.7 36.4 16.8 12.6 25.6 15.1 29.9 12.7 42.3 57.8 7.3 15.3 18.0 21.7 28.3 31.6 19.0 11.4 31.2 8.8 13.7 21.1 21.1 12.9 18.9 51.6 11.1 45.7 9.0 8.1 8.9 22.5 21.4 60.9 37.5 25.7 36.5 39.9 14.6 6.0 4.1 0.8 6.4 6.2 4.1 6.0 5.6 6.1 4.3 6.7 7.2 4.8 0.5 4.0 2.4 6.5 4.0 3.0 16.4 19.8 16.1 22.8 15.4 15.3 17.7 14.9 16.2 13.3 LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244296-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain "HPA008862: AB_2137156" "unprognostic (8.08e-3)" "prognostic unfavourable (4.55e-4)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.60e-2)" "unprognostic (7.59e-3)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (3.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "prognostic favourable (6.71e-7)" "unprognostic (6.53e-2)" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" 15.8 17.0 16.0 13.9 22.2 9.4 36.1 18.9 20.7 16.1 17.4 16.3 15.3 15.2 15.8 20.6 14.5 17.6 19.0 16.7 15.0 15.0 15.9 69.2 11.3 12.8 15.2 15.8 22.1 20.7 40.0 23.3 11.1 17.2 23.1 14.8 30.9 15.0 18.1 18.0 13.5 14.8 16.3 14.1 12.5 14.9 7.0 13.7 14.9 24.9 11.6 13.2 16.7 13.7 13.3 13.1 8.7 13.7 9.0 15.9 11.0 13.7 19.3 9.7 14.9 25.7 21.2 18.4 17.8 13.6 16.7 7.7 10.0 7.1 6.3 17.6 17.8 17.3 19.7 19.6 23.4 10.2 12.4 9.2 12.3 21.8 15.8 15.4 12.4 19.7 21.9 15.6 14.7 12.4 15.5 6.8 17.2 12.4 14.9 7.7 8.1 19.2 19.4 19.8 19.9 18.9 9.3 17.0 10.1 20.1 22.6 17.9 9.5 11.8 16.5 17.3 10.3 15.0 13.6 13.8 12.5 10.4 20.2 10.4 12.5 6.8 13.7 8.7 13.3 13.6 14.0 12.8 15.9 13.5 13.1 13.3 15.0 13.8 5.3 9.0 13.6 9.6 11.8 11.0 16.0 22.2 18.9 20.7 15.0 15.0 15.2 15.8 17.2 13.7 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531483-160664259 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "liver: 43.4" "Cell line enriched" "Detected in single" 6 "RT4: 4.6" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016072, HPA060604" Supported "Secreted to blood" 78800000000 2900000000 "CAB016072: AB_2135240, HPA060604: " "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.2 0.2 43.4 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217285-187292022 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 43.4;liver: 80.1" "Group enriched" "Detected in some" 8 "BJ: 26.5;BJ hTERT+: 101.0" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" 8673000000 1800000000 "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favourable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 2.1 1.4 3.6 1.2 3.8 0.1 1.2 1.9 10.2 43.4 19.1 14.8 2.4 0.8 34.9 7.1 4.1 6.7 3.3 39.6 6.1 2.5 1.6 80.1 2.2 0.4 6.4 3.0 1.7 0.2 0.2 0.5 3.2 13.0 17.4 2.1 0.1 0.9 19.4 12.2 2.5 2.6 17.1 21.8 0.4 0.6 1.5 6.7 0.0 1.3 6.3 3.5 4.4 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.7 0.0 26.5 101.0 0.3 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.8 1.9 3.5 6.1 2.5 6.4 3.0 13.0 6.7 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047233 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 98 "liver: 185.1" "Cell line enriched" "Detected in many" 7 "Hep G2: 20.1" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 4 "cerebellum: 1.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" 339700000 880000000 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favourable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 0.3 0.2 0.3 0.4 0.3 1.8 0.3 1.7 0.5 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.1 0.3 185.1 0.3 0.6 0.3 0.3 0.5 0.4 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.7 0.3 1.4 1.4 0.5 0.3 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.4 1.2 1.2 0.2 0.8 1.3 0.0 0.5 0.3 2.9 1.6 0.0 0.1 0.4 0.8 0.0 0.0 0.0 1.3 1.1 2.3 0.6 0.0 0.7 0.0 0.0 0.0 0.6 2.3 1.4 2.5 20.1 0.0 2.1 1.6 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 0.6 0.6 1.1 0.4 0.6 1.8 1.0 0.5 0.0 1.4 1.8 0.7 0.9 0.5 0.5 0.6 1.3 1.1 0.9 0.6 1.0 0.6 0.7 1.1 1.7 0.6 1.9 0.4 1.2 0.2 1.1 0.7 0.1 1.0 0.7 0.9 0.8 0.5 1.4 1.3 1.3 0.2 0.8 0.2 1.2 0.1 0.0 0.3 0.3 1.7 0.3 0.3 0.1 0.3 0.3 0.3 0.3 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported "HPA056109: " "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favourable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 26.6 25.3 15.2 17.9 32.0 13.2 27.2 29.9 30.2 27.5 23.6 20.5 21.5 15.8 33.5 22.2 18.8 29.2 20.4 31.5 15.7 18.2 23.4 28.9 22.1 17.1 14.8 15.9 34.3 32.6 47.5 38.7 28.5 15.9 24.0 21.2 33.1 29.7 26.8 16.2 18.7 19.0 25.9 11.4 21.8 23.5 17.7 16.1 24.0 36.7 16.7 23.2 26.1 19.6 10.9 11.5 12.8 14.3 14.4 16.7 15.4 15.2 19.4 17.5 24.2 41.2 33.5 13.7 25.7 39.9 22.8 17.3 13.7 22.7 14.7 26.8 36.9 16.9 15.9 17.9 25.4 13.2 17.9 10.7 18.8 19.2 19.9 25.9 23.7 34.4 25.9 21.0 18.1 29.6 13.9 13.0 13.8 26.5 14.2 14.5 16.2 13.9 18.5 9.3 10.6 18.5 12.7 13.3 16.7 49.7 13.8 19.2 43.2 23.9 31.4 23.7 17.4 14.1 12.1 16.5 30.5 28.2 17.3 15.8 14.4 6.6 14.3 12.8 15.8 12.1 16.2 10.9 13.6 14.7 11.5 9.9 16.7 14.8 4.1 14.4 9.8 6.4 8.7 15.4 15.2 32.0 29.9 30.2 15.7 18.2 14.8 15.9 15.9 16.1 OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 9.5;testis: 4.6" "Cell line enriched" "Detected in some" 5 "Daudi: 10.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Secreted in female reproductive system" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" 0.6 0.4 0.0 0.4 0.3 0.1 0.5 0.0 0.1 0.4 0.2 0.0 0.2 0.0 0.1 0.2 0.4 0.2 0.1 0.2 0.2 0.3 9.5 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.1 0.3 0.0 0.0 0.3 0.5 0.1 0.0 0.2 1.9 0.2 4.6 2.1 0.0 0.1 0.2 0.5 0.2 1.3 0.5 0.0 0.6 0.3 0.0 0.0 0.6 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.3 0.0 0.0 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.5 0.8 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.5 0.0 0.6 1.3 0.0 0.0 0.2 0.0 0.3 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 17.5;ASC TERT1: 72.4;BJ hTERT+: 70.4;fHDF/TERT166: 16.7;HSkMC: 24.9;U-87 MG: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted - unknown location" 3300000 "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavourable (5.08e-5)" "prognostic unfavourable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 14.1 9.9 11.9 0.7 10.5 0.4 10.2 0.7 12.8 40.1 6.6 9.7 5.1 3.1 37.0 12.7 6.8 12.1 12.7 11.1 9.5 7.3 2.6 8.0 3.5 1.1 9.9 5.4 4.4 3.4 0.8 3.4 34.0 18.1 12.7 4.6 0.8 2.7 12.1 3.1 12.5 4.7 14.6 13.8 3.7 3.1 5.8 5.7 0.6 3.4 6.0 2.9 18.8 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 72.4 0.0 8.9 70.4 0.9 1.6 6.3 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 10.5 0.0 0.0 24.9 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 10.5 0.7 12.8 9.5 7.3 9.9 5.4 18.1 5.7 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA019545 Approved Approved Mitochondria Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favourable (9.11e-5)" 24.2 20.6 26.2 19.2 30.1 21.2 30.4 22.1 29.6 22.7 29.0 24.4 19.4 21.5 20.2 43.8 21.4 19.6 21.2 30.9 23.1 23.4 27.0 26.7 20.3 26.5 28.4 20.3 20.3 47.5 22.0 20.6 18.5 19.5 22.1 31.3 25.9 35.1 33.4 41.2 22.3 27.0 38.1 19.4 22.3 24.5 22.2 18.9 22.1 20.7 25.4 24.3 23.2 18.2 21.5 45.4 44.3 50.0 21.5 25.9 35.4 32.1 15.3 11.3 9.6 11.0 12.7 23.5 12.1 16.4 23.3 18.3 46.9 16.8 14.3 26.9 15.3 14.3 18.0 18.6 26.3 20.4 22.1 21.6 10.2 25.6 16.6 21.4 18.3 17.2 23.9 16.3 20.0 16.5 12.2 13.4 19.1 34.8 40.9 52.5 30.3 15.7 18.1 22.1 26.0 21.7 26.9 11.4 16.3 14.4 46.4 29.5 47.7 40.7 9.7 8.7 18.9 17.9 30.7 26.9 18.2 33.0 16.6 21.9 10.4 27.6 50.0 44.3 19.0 35.4 21.7 21.5 21.6 22.1 45.4 19.9 25.9 21.1 14.5 21.5 26.2 27.0 24.4 35.4 26.2 30.1 22.1 29.6 23.1 23.4 28.4 20.3 19.5 18.9 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390415-96434143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6" "Group enriched" "Detected in some" 6 "SCLC-21H: 18.5;U-138 MG: 15.8;U-87 MG: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048564 Approved "Secreted in other tissues" "HPA048564: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavourable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 2.3 8.5 1.3 6.0 10.1 0.5 1.3 0.5 36.6 1.2 3.3 0.5 0.0 6.7 0.5 8.8 0.4 0.4 0.6 1.0 2.8 27.1 0.5 0.4 0.8 0.4 3.1 14.0 0.6 9.8 0.3 10.9 0.4 7.5 0.5 3.3 0.1 2.8 0.5 0.5 1.7 4.6 1.0 1.3 0.5 8.4 0.5 0.4 0.0 1.9 0.0 0.3 0.9 0.6 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.0 0.0 0.0 1.7 0.8 0.3 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 2.7 0.0 0.0 0.0 0.0 0.9 15.8 0.5 0.2 0.1 0.0 0.0 0.1 13.1 0.0 0.3 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 10.1 0.5 36.6 2.8 27.1 3.1 14.0 7.5 0.4 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.0;thyroid gland: 79.5" "Group enriched" "Detected in some" 5 "AF22: 35.8;SCLC-21H: 9.4" "Group enriched" "Detected in many" 6 "pancreatic cancer: 14.6;thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Vesicles "HPA049627: " "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 1.6 35.0 16.3 1.7 20.5 1.3 1.3 7.7 27.8 2.9 4.2 1.6 0.0 6.2 0.9 1.2 2.1 2.0 1.4 3.1 18.0 11.1 1.1 1.0 2.2 0.8 4.1 16.2 11.6 23.7 0.9 1.7 1.5 9.0 1.3 2.8 16.6 2.7 2.3 1.0 16.6 3.3 1.3 5.4 0.9 11.9 4.7 3.8 0.0 79.5 0.0 0.9 1.9 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 20.5 7.7 27.8 18.0 11.1 4.1 16.2 9.0 3.8 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 50.7" "Cell line enhanced" "Detected in some" "AN3-CA: 9.9;HMC-1: 5.3;U-266/70: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.2;plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.7;T-cells: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA005572 Uncertain "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favourable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.5 1.2 2.5 0.6 3.4 0.9 0.7 0.6 1.8 1.2 0.9 1.8 2.5 2.5 0.8 2.2 0.7 4.2 1.0 0.4 2.5 2.1 1.7 2.0 0.8 0.6 1.0 2.0 0.8 3.8 1.4 4.2 0.5 2.3 1.2 0.4 2.4 1.3 2.4 0.5 0.8 1.1 0.6 1.2 0.7 1.2 50.7 1.8 1.2 2.0 0.0 0.4 0.7 0.6 0.0 1.7 0.0 0.3 0.0 1.2 0.1 0.8 0.5 1.7 9.9 0.2 0.3 2.6 0.7 0.2 0.1 0.3 0.9 1.4 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.6 0.2 0.4 1.4 1.3 0.7 0.0 5.3 0.8 0.0 0.0 0.1 0.2 1.6 2.5 0.0 0.0 0.2 0.4 0.1 0.5 1.7 0.1 0.2 0.6 0.0 0.0 2.0 0.2 0.4 0.1 3.6 0.5 0.0 0.8 0.1 0.2 0.0 10.9 1.9 0.3 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.7 0.0 0.1 2.5 3.4 0.6 1.8 2.5 2.1 1.0 2.0 2.3 1.8 PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362339 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "blood: 157.6;intestine: 71.5" "Cell line enhanced" "Detected in many" "BEWO: 15.5;HaCaT: 21.8;RH-30: 14.4;RPTEC TERT1: 20.2;U-2 OS: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 157.6;neutrophil: 57.4" "Lineage enriched" "Detected in all" 12 "granulocytes: 157.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavourable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" 15.8 3.8 2.9 13.7 2.8 1.5 9.5 2.4 3.2 8.5 51.8 2.9 4.5 19.7 6.5 13.9 9.6 7.8 22.9 6.7 3.8 2.4 3.7 1.9 7.7 5.6 2.3 3.1 17.2 3.4 9.5 3.2 7.7 3.5 4.5 6.7 3.3 5.0 5.8 4.0 4.8 71.5 6.9 3.5 2.5 3.3 5.1 2.4 18.0 6.4 14.2 4.5 7.1 11.4 11.7 12.2 157.6 4.4 12.6 12.7 0.8 1.1 0.8 2.4 1.6 1.5 0.5 15.5 2.1 0.2 0.1 0.0 8.2 0.9 0.3 0.6 0.2 21.8 1.1 0.6 0.1 0.2 1.9 2.8 1.6 0.7 0.4 0.8 1.3 2.9 0.2 0.5 0.2 4.5 3.2 1.0 1.5 5.1 3.2 4.9 10.6 0.9 0.6 14.4 0.8 20.2 1.2 0.2 0.2 3.3 0.7 0.2 1.2 3.5 3.5 0.7 31.5 1.8 0.9 0.2 0.1 0.4 2.4 1.2 12.0 157.6 4.2 16.2 9.7 2.3 8.3 8.8 9.8 8.9 1.9 11.7 9.9 12.7 57.4 12.6 4.4 12.2 8.4 0.8 2.9 2.8 2.4 3.2 3.8 2.4 2.3 3.1 3.5 2.4 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101297142-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.3;liver: 76.0;lymphoid tissue: 37.4" "Cell line enhanced" "Detected in many" "BEWO: 26.1;CACO-2: 18.3;HEK 293: 27.5;Hep G2: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" 38000 "HPA004774: AB_1079583" "prognostic favourable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavourable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 3.0 1.5 5.1 1.5 25.1 0.9 6.1 4.5 11.5 1.5 8.4 41.9 0.0 3.6 1.4 2.5 4.8 1.9 1.9 10.1 8.9 5.7 1.7 76.0 2.3 4.6 38.8 8.4 4.0 1.7 0.5 3.1 16.5 29.0 1.9 8.2 0.7 1.5 0.7 3.5 4.0 4.8 1.9 69.3 37.4 5.3 6.6 24.5 3.7 1.4 3.5 1.3 1.6 1.6 2.6 0.7 1.9 2.4 7.5 1.4 2.5 8.6 7.0 1.3 0.9 0.1 0.1 26.1 0.5 1.3 0.0 0.1 18.3 4.0 0.2 1.2 0.2 5.9 7.0 0.7 0.1 1.2 27.5 15.0 3.6 24.6 0.8 2.1 0.3 0.4 4.8 0.1 0.2 0.0 11.5 0.2 0.0 4.2 0.1 1.9 3.7 3.0 0.2 0.2 1.9 2.3 12.2 3.5 3.8 12.1 0.9 3.9 1.0 9.5 0.1 0.1 0.7 0.2 0.0 0.3 0.3 0.3 0.1 0.3 3.4 1.3 0.6 1.9 0.6 0.8 0.7 1.1 1.0 0.5 0.2 2.6 1.4 1.3 1.1 7.5 2.4 0.7 0.2 2.5 5.1 25.1 4.5 10.4 8.9 5.7 38.8 8.4 29.0 24.5 PCSK7 "LPC, PC7, PC8, SPC7" ENSG00000160613 "Proprotein convertase subtilisin/kexin type 7" Q16549 11 117204337-117232525 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (7.11e-2)" "unprognostic (2.90e-2)" "unprognostic (8.33e-3)" "unprognostic (4.24e-2)" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.41e-1)" "unprognostic (8.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" 19.4 11.6 11.9 28.7 13.9 11.3 14.4 12.9 16.5 15.0 44.8 15.4 13.4 20.4 47.9 9.4 27.3 23.9 20.7 12.2 10.4 5.2 9.9 11.5 14.5 19.7 18.7 14.1 11.5 14.9 6.2 12.8 18.3 13.3 24.0 17.7 9.6 14.1 11.4 12.8 11.4 20.3 9.2 9.7 16.8 28.4 6.3 13.9 17.8 10.4 13.7 25.3 34.6 13.0 12.7 4.2 4.2 5.3 19.6 19.7 8.7 5.6 10.6 8.7 8.1 9.6 7.3 7.2 22.2 9.1 10.2 9.8 23.8 34.8 9.0 22.2 15.9 19.9 9.8 13.2 6.4 14.0 9.1 13.4 15.4 7.0 11.5 8.5 21.5 13.9 8.2 13.7 9.2 17.5 8.3 8.2 14.3 8.2 11.3 9.8 7.3 10.4 8.3 7.1 11.4 12.3 13.7 11.4 13.7 16.2 21.0 3.0 13.0 7.7 16.2 24.4 8.1 13.7 14.6 5.6 3.4 5.7 7.9 12.3 14.6 3.9 3.3 4.2 19.5 4.7 16.4 12.7 15.2 17.8 3.7 9.6 11.0 12.7 2.8 19.6 5.3 4.2 19.7 8.7 11.9 13.9 12.9 16.5 10.4 5.2 18.7 14.1 13.3 13.9 PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039548-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 47.1;lung: 14.6" "Cell line enhanced" "Detected in some" "A-431: 28.4;HaCaT: 38.1;HeLa: 33.2;RPTEC TERT1: 18.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 9 "cerebellum: 6.9;pons and medulla: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" 143000000 300000000 "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavourable (2.40e-4)" 0.2 0.1 0.0 6.1 0.5 0.4 0.0 6.9 0.2 0.6 4.4 0.0 0.0 3.9 0.2 0.7 5.2 0.4 2.6 0.0 0.0 0.0 0.1 47.1 14.6 0.0 0.1 0.0 0.1 11.0 0.0 0.0 0.0 2.6 0.0 1.9 0.1 0.3 0.3 0.0 0.8 5.1 0.8 0.1 0.2 1.0 0.4 0.0 0.0 0.0 6.1 0.9 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 6.3 0.9 0.0 2.1 1.4 0.0 0.0 0.0 0.0 0.0 13.2 4.5 0.0 5.2 2.5 38.1 1.1 11.6 0.0 0.0 0.0 0.0 33.2 9.2 0.7 0.0 0.0 2.2 8.6 8.4 6.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.4 0.6 0.0 0.0 0.3 18.8 0.0 0.5 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.2 0.0 0.0 0.1 0.0 2.6 0.0 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42175233-42207724 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 132.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.8;HMC-1: 55.1;LHCN-M2: 55.6;U-2197: 58.0;WM-115: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 2.1;T-reg: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" 9900000 12000 "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favourable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 19.3 14.9 5.2 12.9 6.8 0.4 13.3 2.2 6.2 24.5 17.1 9.1 19.0 11.2 35.5 28.1 18.1 19.1 18.5 7.3 6.0 5.9 67.6 2.8 15.9 1.9 8.2 3.6 18.4 5.8 132.2 5.1 15.5 9.4 27.4 12.2 39.4 6.1 12.7 5.8 2.0 31.7 23.0 7.0 1.0 14.6 12.2 3.8 0.6 11.2 14.7 7.4 47.9 13.7 0.3 0.1 1.6 0.0 0.0 2.3 0.3 0.5 0.2 4.2 1.0 7.7 10.5 0.1 18.0 32.0 7.7 6.6 0.2 85.8 0.0 0.6 2.3 1.4 0.0 4.0 15.9 7.8 1.4 0.1 0.1 0.1 37.9 0.0 55.1 10.5 0.0 18.8 0.7 14.4 0.5 0.1 55.6 0.0 0.0 0.0 5.6 7.6 0.0 15.6 0.0 2.5 0.0 0.0 0.9 0.0 0.1 24.5 0.1 0.0 27.5 1.5 5.7 58.0 1.8 0.0 0.1 0.0 1.2 0.0 115.3 1.6 0.0 0.0 0.3 0.0 1.0 0.3 2.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 5.2 6.8 2.2 6.2 6.0 5.9 8.2 3.6 9.4 3.8 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917497 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 48.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 68.9;LHCN-M2: 66.5;RPTEC TERT1: 252.9;U-251 MG: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 2.4;neutrophil: 4.5;plasmacytoid DC: 4.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.5;granulocytes: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008719 Approved "Secreted to blood" 647333 58000 "HPA008719: AB_1858635" "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favourable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavourable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavourable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 26.7 2.4 1.0 15.5 2.1 11.3 9.7 1.6 1.5 6.9 5.8 2.9 4.9 3.8 10.7 21.2 9.1 6.5 10.7 14.3 1.3 1.0 23.3 2.3 23.4 5.5 1.6 1.5 6.8 3.7 3.6 1.8 48.4 3.1 7.5 6.7 4.5 10.6 5.0 12.2 9.0 8.1 8.4 2.5 23.8 7.8 5.8 1.3 4.8 10.9 11.6 8.2 16.3 9.3 0.1 4.5 4.5 0.4 0.0 0.0 0.3 13.0 7.0 3.0 0.1 0.2 5.0 0.1 7.9 37.2 3.2 5.1 0.1 68.9 0.0 14.7 1.1 9.0 0.0 13.3 3.7 0.7 0.0 0.0 0.3 0.1 6.1 1.1 2.6 13.3 1.6 22.2 8.6 9.2 0.0 0.0 66.5 0.0 0.0 1.7 0.8 18.3 0.0 9.0 0.0 252.9 10.3 0.0 0.0 0.0 0.3 0.2 0.0 1.8 23.3 0.2 1.6 1.7 67.9 0.0 0.1 0.1 17.9 1.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 4.5 0.0 0.0 4.5 0.0 0.3 1.0 2.1 1.6 1.5 1.3 1.0 1.6 1.5 3.1 1.3 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160753315 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 269.9" "Cell line enhanced" "Detected in some" "HL-60: 3.5;RH-30: 3.9;U-698: 2.0;U-937: 1.6" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" 140000000000 41000000000 "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: " "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favourable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 269.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.2 0.8 0.0 0.4 3.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 1.0 0.0 2.0 0.0 1.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82823502-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" 34000000 Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favourable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 32.6 45.9 25.0 21.5 22.2 13.1 69.5 19.4 23.8 38.8 17.9 17.9 27.6 11.0 30.7 35.5 32.2 24.6 25.6 66.3 25.8 18.9 52.4 52.5 38.1 95.1 27.0 14.8 27.8 23.4 30.6 19.3 59.8 34.9 25.1 18.4 25.1 38.1 34.5 10.3 26.2 15.7 32.8 45.0 25.1 16.8 17.4 17.7 9.8 27.9 24.2 31.7 39.4 30.1 13.1 50.0 31.2 27.9 12.1 6.2 14.7 7.5 8.2 12.6 25.4 97.9 35.9 14.8 16.0 28.6 15.4 22.5 20.3 15.5 10.8 23.4 23.2 11.9 11.5 10.5 18.0 9.6 8.3 7.7 11.4 12.6 18.3 6.9 28.2 26.2 8.3 16.0 15.2 50.8 8.3 15.2 15.7 3.4 1.0 24.7 7.3 7.7 5.6 21.9 12.9 21.5 13.8 5.3 11.5 21.9 12.7 9.0 15.2 9.5 13.2 18.1 18.1 15.6 7.8 14.3 24.4 9.6 7.4 8.4 9.3 15.5 26.4 17.4 5.3 27.9 6.1 9.9 5.3 5.8 50.0 13.1 4.4 6.2 31.2 12.1 21.2 8.9 5.0 14.7 25.0 22.2 19.4 23.8 25.8 18.9 27.0 14.8 34.9 17.7 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol 1400000 Cytosol "CAB025414: , HPA031388: , HPA031389: , HPA031390: " "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavourable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 10.8 13.3 14.2 15.9 33.6 19.9 14.0 14.6 13.7 19.3 20.5 16.9 6.9 13.9 14.4 17.1 16.9 20.9 42.8 22.0 21.0 20.4 18.7 11.2 19.2 13.0 18.8 13.7 18.5 26.1 13.9 35.8 18.0 31.8 24.9 23.3 17.6 12.5 19.1 13.7 13.3 19.4 24.5 9.1 14.4 25.9 18.6 26.5 12.8 21.5 10.2 9.2 30.2 18.1 8.9 12.3 11.1 17.9 7.3 4.8 18.2 15.7 20.5 27.6 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 PREPL KIAA0436 ENSG00000138078 "Prolyl endopeptidase like" Q4J6C6 2 44316281-44361862 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063238 Approved "HPA063238: " "unprognostic (5.60e-3)" "unprognostic (9.81e-2)" "unprognostic (4.51e-2)" "unprognostic (4.65e-3)" "unprognostic (2.22e-1)" "unprognostic (8.53e-2)" "unprognostic (5.98e-3)" "unprognostic (4.38e-3)" "unprognostic (2.27e-1)" "unprognostic (2.72e-2)" "unprognostic (1.52e-2)" "unprognostic (4.67e-2)" "unprognostic (2.33e-2)" "unprognostic (3.79e-1)" "unprognostic (1.87e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" 11.5 24.5 32.6 8.2 78.4 2.5 15.0 57.3 75.8 18.1 11.3 18.7 6.0 12.0 22.1 34.2 10.9 16.4 13.4 28.2 51.8 50.2 30.4 9.9 11.4 7.6 28.5 44.0 24.3 11.6 34.9 33.2 9.9 69.4 18.1 14.1 13.0 11.7 16.5 13.7 10.2 12.6 16.3 31.3 10.5 12.1 12.6 21.5 5.2 28.9 7.1 8.2 10.7 10.3 8.8 6.3 4.7 4.8 11.1 12.5 5.8 18.3 14.1 16.3 20.7 26.5 27.8 12.5 20.7 15.7 14.9 12.9 15.3 13.0 23.6 28.7 21.5 15.9 23.5 15.0 28.7 21.6 16.6 16.5 11.3 11.6 19.2 15.6 15.2 17.9 30.0 28.7 23.3 14.3 20.2 34.3 19.9 9.8 17.1 7.6 15.7 16.1 13.5 19.9 16.8 28.5 10.7 28.1 21.8 13.5 14.2 29.9 19.0 12.4 15.0 26.5 15.0 20.7 14.0 18.9 12.4 15.5 31.0 18.6 19.5 4.7 4.5 3.4 8.5 4.8 12.2 8.8 8.1 9.2 6.3 7.4 12.5 9.7 1.3 11.1 4.1 3.1 8.7 5.8 32.6 78.4 57.3 75.8 51.8 50.2 28.5 44.0 69.4 21.5 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429246 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 137.5" "Cell line enriched" "Detected in some" 16 "Hep G2: 57.5" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 29.2" "Lineage enriched" "Detected in many" 9 "dendritic cells: 29.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Supported "Secreted to blood" 6400000000 "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.2 4.2 137.5 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 29.2 3.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.5 0.0 0.3 0.0 3.6 0.0 0.1 0.0 0.0 0.0 0.0 2.7 57.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 29.2 0.0 0.1 0.4 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.4 0.0 PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158654-113172383 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 45.0" "Cell line enhanced" "Detected in some" "HaCaT: 4.8;Hep G2: 7.6" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.7;T-reg: 1.5" "Group enriched" "Detected in many" 12 "monocytes: 2.7;T-cells: 1.5" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" 1716566667 510000000 "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favourable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.0 9.3 45.0 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 2.7 0.0 1.5 0.2 0.9 1.4 0.7 1.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 3.0 1.8 0.8 0.0 0.0 4.8 0.0 0.0 0.0 0.8 2.4 1.0 2.8 7.6 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 1.0 0.6 0.8 1.8 0.4 1.3 0.2 0.3 0.0 1.1 2.9 0.2 0.0 0.3 1.3 0.0 1.0 0.7 0.8 0.1 0.8 0.3 1.6 0.9 0.8 1.6 0.9 0.7 0.0 0.0 0.0 0.3 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.1 1.5 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1708 "pancreas: 3057.4" "Cell line enhanced" "Detected in some" "EFO-21: 3.5;HDLM-2: 1.7;RPMI-8226: 6.9;U-2 OS: 4.1;U-251 MG: 1.5;U-266/84: 2.5" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in many" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 26000000000 Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: , HPA063471: " "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavourable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favourable (4.91e-4)" "unprognostic (3.12e-1)" 0.4 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3057.4 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 0.0 1.7 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 1.5 0.0 2.5 0.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.5;testis: 31.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.4;SH-SY5Y: 64.8;THP-1: 29.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 11.6;basal ganglia: 8.7;cerebral cortex: 26.5;hippocampal formation: 15.3;olfactory region: 11.0" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favourable (2.66e-4)" "prognostic favourable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.9 0.5 2.1 4.1 1.4 0.0 1.9 0.5 2.8 16.5 6.0 2.0 1.3 2.2 3.0 2.7 3.6 9.8 27.5 0.3 2.2 0.9 1.1 0.8 8.0 0.0 0.7 2.4 1.9 9.8 0.0 0.9 20.4 4.1 2.0 5.8 20.0 3.1 3.2 0.3 5.9 8.6 1.0 0.5 0.3 8.1 31.3 0.2 0.3 0.6 7.7 7.7 3.1 16.2 0.3 0.4 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.5 0.0 0.0 4.1 0.0 13.5 12.2 2.9 4.8 0.0 5.5 0.0 0.0 20.4 0.2 9.1 2.7 3.8 0.0 2.1 0.0 1.1 0.0 0.4 0.0 0.0 1.2 5.2 1.0 3.0 0.0 0.0 0.0 2.3 0.0 0.1 2.7 0.6 0.8 0.0 11.5 0.0 0.0 2.0 1.5 64.8 0.0 0.0 0.8 0.0 29.0 0.0 5.8 0.8 3.6 2.6 0.3 0.0 0.0 0.3 0.9 3.3 0.0 0.1 0.0 0.0 0.1 0.7 0.3 0.0 0.0 0.4 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.1 1.4 0.5 2.8 2.2 0.9 0.7 2.4 4.1 0.2 PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 242.8" "Cell line enhanced" "Detected in some" "hTCEpi: 19.5;RPMI-8226: 10.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory B-cell: 5.4" "Group enriched" "Detected in many" 39 "B-cells: 5.4;T-cells: 2.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted in other tissues" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favourable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" 0.9 0.5 0.9 0.9 0.9 0.0 3.6 0.9 0.9 2.0 3.3 0.9 0.9 2.3 0.9 9.3 3.6 3.3 2.1 0.9 0.9 0.0 1.4 0.9 2.4 0.9 0.9 0.9 1.2 17.1 6.4 1.8 2.1 0.9 1.8 4.1 0.9 4.3 2.5 0.9 2.9 2.8 0.9 0.9 0.9 3.9 0.9 0.9 242.8 8.7 0.9 0.9 2.0 1.1 5.4 0.0 0.0 0.0 0.0 2.3 0.4 2.9 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 3.4 4.5 0.0 0.7 0.0 1.5 2.5 3.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 1.9 0.5 0.0 19.5 0.0 4.0 0.0 2.2 1.8 0.0 1.1 0.4 0.0 0.6 0.5 0.0 0.0 10.5 2.3 3.4 0.0 0.0 1.3 3.0 0.0 1.9 0.8 0.0 0.0 0.7 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 2.0 5.4 2.3 1.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.9 0.9 0.9 0.9 0.9 0.0 0.9 0.9 0.9 0.9 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 708 "pancreas: 6267.9" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 37.2" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Group enriched" "Detected in some" 6 "basophil: 5.6;T-reg: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.6;T-cells: 5.1" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 27000000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "prognostic favourable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6267.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 5.6 0.0 0.7 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.4 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.5 2.1 0.0 1.6 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.3 PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 21.0;salivary gland: 20.9;testis: 37.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.2;HEL: 11.3;HeLa: 29.2;K-562: 13.4;U-698: 41.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 10.5;eosinophil: 21.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 21.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 27 "basal ganglia: 6.7" HPA008477 Enhanced Approved Cytosol "Intracellular and membrane" Cytosol "HPA008477: AB_1079697" "unprognostic (4.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.06e-2)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "unprognostic (8.83e-3)" "unprognostic (1.52e-3)" "unprognostic (2.97e-2)" "unprognostic (1.14e-2)" "unprognostic (5.07e-2)" "unprognostic (7.79e-2)" "unprognostic (2.99e-1)" 0.8 0.0 0.2 0.2 0.2 5.5 1.0 0.4 0.4 1.4 0.4 0.2 1.4 0.2 0.3 0.2 0.8 2.2 2.1 0.2 0.2 0.0 0.2 0.2 2.1 3.3 0.2 0.2 0.3 0.9 1.7 0.2 0.3 0.4 1.8 0.2 0.2 20.9 0.2 0.5 0.4 0.4 0.2 0.2 0.9 0.4 37.5 0.2 0.9 0.2 1.2 1.1 0.3 0.6 0.8 1.4 21.0 2.3 1.0 3.3 1.3 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 11.3 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 10.5 2.3 21.0 2.2 1.6 3.3 0.8 1.1 1.8 0.6 0.6 1.5 2.2 0.2 1.0 0.3 1.4 0.5 1.3 0.2 0.2 0.4 0.4 0.2 0.0 0.2 0.2 0.4 0.2 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852727-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.4;lymphoid tissue: 40.1;tongue: 36.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.6;MCF7: 12.4;RT4: 5.8;SK-BR-3: 13.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 16 "cerebellum: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" Nucleoplasm "HPA049161: " "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.4 0.7 0.0 0.4 0.0 0.6 1.3 1.5 0.4 9.9 1.0 0.0 8.6 1.5 3.0 0.6 40.4 3.0 6.8 0.4 0.0 0.0 2.4 0.7 3.0 0.4 0.0 0.0 0.4 7.5 0.4 1.1 4.3 0.0 5.1 0.6 0.0 13.4 10.6 2.3 1.3 0.4 0.7 0.0 0.4 3.5 0.4 0.0 0.0 1.5 36.5 40.1 5.2 9.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 13.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 59.0;HUVEC TERT2: 73.6;TIME: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 36.4" "Group enriched" "Detected in many" 30 "NK-cells: 10.2;T-cells: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030591 Uncertain "Secreted to blood" 290000 "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavourable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavourable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavourable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 19.5 8.7 2.3 10.8 4.1 0.4 40.7 1.2 2.6 89.0 33.8 2.1 37.2 5.1 44.9 27.4 14.5 9.6 45.6 17.2 5.0 3.0 17.5 10.4 36.2 15.9 3.7 4.4 16.2 14.3 9.6 6.3 30.2 12.5 36.7 14.4 15.2 17.6 37.3 19.1 7.2 12.4 100.2 4.9 7.3 22.0 19.5 1.4 3.8 15.3 10.5 5.8 68.6 31.1 0.0 0.0 0.5 0.7 10.2 36.4 10.9 7.3 18.5 19.9 0.1 8.9 21.9 0.0 32.5 29.9 36.3 29.1 42.9 59.0 0.0 25.9 49.8 15.3 0.3 24.8 8.8 0.0 1.5 2.5 9.5 0.1 4.5 0.0 0.1 17.4 3.3 17.7 20.2 73.6 0.1 0.0 27.3 10.1 0.0 0.0 1.2 2.0 0.0 0.0 0.0 13.6 9.9 0.1 0.1 7.2 0.5 2.2 0.7 0.0 137.4 21.7 0.2 43.3 18.4 0.1 0.1 0.0 15.5 0.0 21.4 0.0 0.0 0.0 36.4 0.0 0.0 0.0 6.6 20.5 0.0 0.0 1.8 18.5 0.5 10.2 0.7 0.0 0.0 10.9 2.3 4.1 1.2 2.6 5.0 3.0 3.7 4.4 12.5 1.4 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712418-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 94.1;lymphoid tissue: 97.2;tongue: 64.5" "Cell line enhanced" "Detected in some" "BEWO: 5.4;SK-BR-3: 21.8;T-47d: 12.8;U-266/70: 4.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 1.4;myeloid DC: 1.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;T-cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 0.2 0.3 0.1 0.2 0.5 0.2 0.4 0.7 0.4 15.3 0.2 0.1 0.1 0.1 1.2 0.1 94.1 0.3 0.2 0.2 0.1 0.4 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.1 0.2 0.1 0.1 10.0 0.3 0.2 1.2 0.1 0.2 0.1 0.2 0.1 0.5 0.1 0.3 0.2 64.5 97.2 0.5 24.0 0.1 1.7 0.2 0.0 0.2 1.4 1.2 0.0 0.2 0.5 1.8 0.3 0.6 5.4 0.0 0.2 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.1 0.1 0.0 0.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.6 0.0 0.9 1.3 0.0 0.8 0.2 0.1 0.1 0.3 0.6 2.6 0.0 21.8 0.5 12.8 1.5 0.0 0.3 0.0 0.0 0.0 4.5 3.1 0.4 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.0 1.7 0.0 0.3 0.7 0.2 0.2 0.0 0.0 0.0 1.2 0.1 0.5 0.7 0.1 0.1 0.4 0.1 0.1 0.1 0.1 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750466-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "pancreas: 984.9" "Cell line enriched" "Detected in some" 8 "PC-3: 121.9" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 82 "basophil: 39.0" "Lineage enriched" "Detected in single" 82 "granulocytes: 39.0" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 490000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 0.3 0.3 1.6 1.7 1.5 0.2 0.2 2.8 4.2 0.9 8.2 0.0 0.0 2.8 0.2 0.2 2.9 0.2 4.8 0.4 1.2 0.7 0.3 0.4 0.2 0.2 0.3 1.6 0.7 984.9 0.2 0.1 0.2 2.3 0.2 2.3 0.0 0.6 0.2 0.2 2.0 23.9 0.3 0.2 0.2 0.8 0.3 0.0 0.0 0.2 6.6 3.5 0.2 1.3 0.0 0.1 39.0 0.4 0.1 0.3 0.1 1.7 2.0 0.1 0.0 0.0 0.9 0.0 4.8 1.1 0.5 0.2 4.7 0.4 0.0 0.0 2.1 2.1 0.0 4.4 1.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 15.9 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 121.9 0.0 0.0 0.0 0.0 0.2 0.0 12.3 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 39.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 1.6 1.5 2.8 4.2 1.2 0.7 0.3 1.6 2.3 0.0 PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "blood: 132.7" "Group enriched" "Detected in some" 9 "HMC-1: 5.1;SK-MEL-30: 10.4;U-2 OS: 3.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.0" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 78 "eosinophil: 132.7" "Lineage enriched" "Detected in single" 422 "granulocytes: 132.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "unprognostic (4.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.99e-2)" "unprognostic (3.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.16e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" 0.0 0.0 0.3 1.1 0.3 0.1 0.1 0.2 0.4 0.2 0.2 0.2 0.0 0.8 0.1 0.0 0.1 10.2 3.6 0.0 0.1 0.1 0.3 0.0 0.2 1.1 0.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.2 22.5 1.9 0.0 0.0 0.0 1.8 0.8 0.0 0.7 1.1 0.9 0.2 0.2 0.2 1.0 0.2 1.0 0.0 0.0 0.0 132.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 132.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.1 0.1 0.1 0.0 0.0 0.2 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512538-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 17.1;ovary: 16.3" "Group enriched" "Detected in some" 4 "CACO-2: 42.1;RPTEC TERT1: 12.4" "Cancer enhanced" "Detected in some" "testis cancer: 4.7" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "MAIT T-cell: 17.1" "Lineage enriched" "Detected in single" 172 "T-cells: 17.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;cerebellum: 7.0;cerebral cortex: 7.5;hippocampal formation: 6.8;olfactory region: 5.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 2.0 3.8 7.7 1.3 11.3 0.0 0.6 0.2 9.3 4.8 0.4 2.5 0.3 0.5 2.2 2.1 0.6 2.2 6.2 5.6 4.8 1.1 4.9 0.7 2.0 3.0 1.1 5.4 16.3 0.6 0.9 1.5 5.2 2.7 2.7 0.6 11.1 0.4 0.7 0.4 0.5 0.4 2.2 1.4 1.1 0.6 4.6 1.3 0.0 0.7 0.4 0.2 2.0 0.9 0.0 0.0 0.0 0.0 0.0 17.1 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 5.1 0.5 1.0 42.1 0.0 0.0 0.0 0.2 0.0 6.3 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 4.1 0.0 0.0 0.0 12.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 17.1 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.7 11.3 0.2 7.1 4.8 1.1 1.1 5.4 2.7 1.3 PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138925-31150094 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.2;HeLa: 6.3;HMC-1: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "eosinophil: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036079 Uncertain "Secreted - unknown location" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favourable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" 3.0 2.0 0.4 1.0 1.2 1.1 6.2 0.4 1.8 1.6 1.8 0.4 0.4 3.2 0.4 1.8 1.2 0.5 0.4 2.1 0.4 0.5 0.5 0.7 2.3 0.4 0.4 0.4 1.7 0.4 0.4 6.5 2.5 0.4 1.0 0.9 0.4 3.5 0.4 1.3 3.4 2.1 1.2 0.4 0.4 1.0 0.7 0.4 0.4 0.6 0.4 1.0 2.0 0.4 0.0 2.1 4.3 0.8 0.2 0.4 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.3 0.3 0.2 0.1 0.4 1.4 0.0 0.8 0.3 1.3 0.1 0.2 0.0 0.2 0.6 2.2 6.3 1.1 0.1 0.3 2.8 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.5 0.0 0.3 0.4 0.1 0.5 0.1 0.0 0.0 0.2 0.3 0.0 0.6 0.7 0.0 0.1 1.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 4.3 0.2 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.1 0.4 2.6 0.2 0.0 0.6 0.1 0.1 0.4 1.2 0.4 1.8 0.4 0.5 0.4 0.4 0.4 0.4 PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836286-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "testis: 39.1" "Cell line enhanced" "Detected in some" "HL-60: 2.3;U-937: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020541 Enhanced "Secreted in male reproductive system" "HPA020541: AB_1853004" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-2)" "unprognostic (8.30e-7)" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815693-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "blood: 2.2;testis: 8.4" "Cell line enriched" "Detected in single" 20 "U-266/84: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "gdT-cell: 1.4;NK-cell: 2.2" "Group enriched" "Detected in many" 18 "NK-cells: 2.2;T-cells: 1.4" "Not detected" "Not detected" "HPA028003, HPA055809" Enhanced "Secreted in male reproductive system" "HPA028003: AB_1853572, HPA055809: AB_2682931" "unprognostic (9.54e-3)" "unprognostic (3.61e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 PRSS41 TESSP1 ENSG00000215148 "Serine protease 41" Q7RTY9 16 2798485-2805302 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 11.6;testis: 4.0" "Cell line enriched" "Detected in single" 11 "BEWO: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Cell type enriched" "Detected in single" 116 "eosinophil: 11.6" "Lineage enriched" "Detected in single" 116 "granulocytes: 11.6" "unprognostic (1.58e-1)" "unprognostic (3.65e-1)" "unprognostic (3.04e-3)" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (1.24e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 1.2 4.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS42 TESSP2 ENSG00000178055 "Serine protease 42" Q7Z5A4 3 46829542-46834095 "Enzymes, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "heart muscle: 12.9;skeletal muscle: 19.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.3;Daudi: 3.9;Karpas-707: 2.4;NTERA-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046925 Uncertain "Secreted - unknown location" "HPA046925: AB_10961401" "unprognostic (6.53e-2)" "unprognostic (2.72e-2)" "unprognostic (3.57e-3)" "unprognostic (9.14e-2)" "unprognostic (3.26e-1)" "unprognostic (2.37e-2)" "unprognostic (1.85e-1)" "unprognostic (6.54e-2)" "unprognostic (4.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.62e-1)" "unprognostic (7.98e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.2 0.0 0.2 3.4 0.0 0.2 0.0 12.9 0.0 0.0 1.3 0.5 0.2 0.0 0.0 0.2 0.2 1.6 0.0 0.1 0.4 0.0 0.3 0.2 19.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.8 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.8 0.2 1.6 0.0 0.0 0.0 0.7 0.2 2.3 3.9 0.4 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.4 3.6 0.0 1.2 0.0 0.0 0.1 0.0 0.6 0.5 0.5 0.0 0.3 0.0 0.5 0.0 1.0 0.7 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS45 TESSP5 ENSG00000188086 "Serine protease 45" Q7RTY3 3 46742092-46744755 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 7.6;skeletal muscle: 6.7" "Cell line enhanced" "Detected in some" "Daudi: 1.2;HBF TERT88: 1.0;HHSteC: 2.6" "Low cancer specificity" "Detected in single" "Cell type enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" HPA060284 Uncertain "HPA060284: " "unprognostic (4.55e-3)" "unprognostic (3.49e-2)" "unprognostic (1.07e-2)" "unprognostic (2.50e-1)" "unprognostic (6.07e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (6.20e-2)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-4)" "unprognostic (2.33e-2)" "unprognostic (6.60e-3)" "unprognostic (1.27e-2)" "unprognostic (1.57e-2)" "unprognostic (2.15e-1)" "unprognostic (5.97e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.5 0.2 0.1 0.2 7.6 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.7 0.2 0.1 0.0 0.3 1.3 2.0 0.5 0.1 0.5 0.0 0.5 0.3 6.7 0.3 0.0 0.0 0.0 0.0 0.2 1.6 3.2 0.0 0.4 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277171-151291453 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 1.0;skin 1: 1.9;testis: 4.1" "Cell line enhanced" "Detected in some" "HHSteC: 1.4;LHCN-M2: 1.3;PC-3: 1.5;RT4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted in male reproductive system" "HPA053801: " "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 PRSS50 "CT20, TSP50" ENSG00000206549 "Serine protease 50" Q9UI38 3 46712115-46812574 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.3" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NTERA-2: 2.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported "HPA040768: " "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.32e-1)" "unprognostic (7.45e-2)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (8.91e-4)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (2.68e-2)" "unprognostic (1.79e-2)" "unprognostic (9.36e-2)" "unprognostic (3.66e-3)" 0.1 0.7 0.0 0.0 0.0 0.0 0.6 0.4 0.3 1.3 0.2 0.1 0.7 6.2 0.1 0.5 0.0 0.9 0.0 0.6 1.8 0.7 0.2 0.0 0.0 0.7 1.7 4.7 8.2 0.0 1.6 0.0 1.7 1.7 7.7 0.0 0.0 0.2 0.0 0.0 0.2 22.3 7.9 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS50 "CT20, TSP50" ENSG00000283706 "Serine protease 50" Q9UI38 3 46712115-46717907 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 33.4" "Cell line enhanced" "Detected in some" "EFO-21: 2.0;HMC-1: 5.3;NTERA-2: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported "Intracellular and membrane" "HPA040768: " 0.1 0.8 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 2.9 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.3 0.9 1.7 1.1 0.1 0.1 0.2 0.0 0.1 1.6 1.8 0.1 0.0 0.1 0.1 0.1 0.1 0.0 33.4 0.1 0.4 1.6 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Group enriched" "Detected in some" 5 "brain: 1.4;breast: 3.4;liver: 1.5;testis: 2.3" "Cell line enhanced" "Detected in some" "AN3-CA: 1.7;CAPAN-2: 1.6;T-47d: 1.9;U-2 OS: 5.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.4 3.4 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.6 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083425-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 10.9" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034955, HPA034956" Uncertain "Secreted - unknown location" "HPA034955: , HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" 0.3 0.0 0.0 0.5 0.3 0.0 0.1 2.9 0.4 0.2 0.3 1.4 1.0 0.0 0.1 0.3 0.6 0.2 0.1 0.3 0.6 10.9 0.5 0.9 0.1 0.3 2.2 0.0 0.8 0.2 1.2 0.0 0.0 0.8 0.0 3.9 0.5 0.4 0.2 1.0 1.3 0.0 0.3 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.8 0.3 0.0 0.3 0.0 0.0 0.0 1.0 0.5 1.1 1.0 0.0 0.2 0.0 0.3 0.7 0.0 1.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.1 0.3 0.1 1.3 0.3 1.6 0.8 1.9 1.6 0.0 0.0 0.0 0.0 9.8 0.8 0.9 0.0 1.0 0.7 0.1 0.7 1.0 0.7 2.5 0.2 1.4 0.1 0.3 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 95 "testis: 35.1" "Cell line enhanced" "Detected in single" "BEWO: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041549 Enhanced "Secreted in male reproductive system" "HPA041549: AB_10795640" "unprognostic (1.13e-1)" "unprognostic (3.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525546-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 67 "testis: 25.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" "unprognostic (3.64e-1)" "unprognostic (8.44e-3)" "unprognostic (6.10e-2)" "unprognostic (7.40e-2)" "unprognostic (6.23e-5)" "unprognostic (6.62e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520463-232525716 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;retina: 8.6;skeletal muscle: 16.2" "Cell line enriched" "Detected in single" 5 "Daudi: 4.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.7" "Region enhanced" "Detected in many" "hypothalamus: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basal ganglia: 1.6;olfactory region: 5.2" "Region enhanced" "Detected in many" "olfactory region: 32.6" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" 0.1 0.1 0.3 0.1 1.8 0.1 0.1 0.1 1.0 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.1 0.1 0.2 4.4 0.1 0.1 0.1 0.1 2.2 0.1 0.6 0.1 0.1 0.1 0.1 0.1 0.2 0.1 8.6 0.1 0.1 16.2 0.1 0.1 0.1 0.8 0.2 0.1 2.6 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.1 1.0 0.2 4.4 2.2 0.1 0.1 0.1 PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 61.8" "Group enriched" "Detected in some" 13 "NB-4: 85.1;THP-1: 42.6" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 8.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted to blood" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" 0.3 0.2 0.0 0.0 0.0 61.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.6 0.0 3.9 0.0 0.1 0.2 0.8 4.0 0.1 0.1 0.0 0.9 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.1 0.0 0.2 0.0 9.3 0.3 0.0 0.9 0.0 0.2 0.0 2.2 8.7 1.6 3.1 4.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 85.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 8.7 1.6 0.0 0.6 0.3 0.0 0.0 0.0 4.5 2.2 0.0 0.0 0.8 1.0 3.1 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 27.2" "Cell line enriched" "Detected in single" 22 "RH-30: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in male reproductive system" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 123.2;salivary gland: 143.7" "Cell line enhanced" "Detected in some" "BEWO: 57.3;CACO-2: 37.6;CAPAN-2: 25.8;hTCEpi: 37.0;SK-BR-3: 43.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "pons and medulla: 3.4" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA030436 Uncertain "Secreted - unknown location" 3500000 "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favourable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.3 0.2 0.3 11.5 0.3 0.0 7.6 0.7 0.4 8.0 72.6 0.6 12.8 31.6 3.4 46.7 37.2 2.8 45.3 0.3 0.4 0.3 48.0 20.3 30.0 0.3 0.3 0.3 1.3 46.3 2.7 2.6 93.1 3.4 11.4 14.7 1.1 143.7 7.4 0.3 29.7 123.2 0.5 0.3 0.3 37.0 1.8 0.3 11.3 33.4 18.4 26.7 2.6 13.4 0.2 0.0 1.0 0.3 0.0 0.2 0.0 14.2 0.0 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 37.6 25.8 0.0 0.3 0.0 17.0 0.0 16.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 37.0 0.0 0.5 0.0 0.4 0.0 0.0 15.3 0.1 0.3 4.7 0.0 0.1 0.0 0.2 1.7 3.0 0.2 0.1 0.0 43.5 0.0 9.9 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.4 0.4 0.3 0.3 0.3 3.4 0.3 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840960-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 167.3" "Cell line enriched" "Detected in some" 5 "THP-1: 148.0" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced "Secreted to blood" 120000 "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.3 0.2 0.9 0.2 1.0 167.3 0.2 0.0 2.3 0.2 0.2 0.7 0.0 0.2 0.2 0.2 0.2 0.2 0.2 31.0 0.3 0.6 0.2 1.7 8.1 3.5 0.1 0.1 0.4 0.2 0.2 0.8 4.2 0.8 0.2 0.2 0.3 0.3 0.2 0.5 0.3 0.2 0.2 0.0 25.5 0.2 0.2 0.1 35.0 0.9 0.0 0.2 0.2 0.0 0.0 0.0 1.9 0.1 0.0 0.2 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 6.8 0.9 1.0 0.0 2.3 0.3 0.6 0.1 0.1 0.8 0.1 RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348371-47357875 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Transport "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "retina: 135.2" "Group enriched" "Detected in some" 8 "HaCaT: 2.6;HDLM-2: 2.4;SH-SY5Y: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" "HPA041301: , HPA044239: " "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 135.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: " "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 12.7 14.8 10.8 16.7 16.0 11.0 13.6 8.3 13.0 13.8 14.3 21.2 9.4 11.0 20.6 16.3 13.6 15.4 12.4 14.5 11.4 9.0 13.6 16.9 12.6 17.7 17.6 11.0 18.8 20.4 18.6 17.1 10.5 13.0 15.7 12.4 13.1 14.3 15.5 13.9 13.0 17.5 15.6 16.5 17.3 13.2 25.6 14.7 56.6 17.3 8.8 18.9 18.7 15.4 19.9 16.6 9.8 15.5 8.8 12.5 8.5 5.1 4.4 4.7 7.2 14.3 14.2 0.0 12.2 9.8 6.0 6.9 3.8 8.9 4.8 10.2 12.3 6.0 0.0 12.7 11.6 12.3 4.9 7.0 2.9 3.4 15.4 7.5 4.1 13.3 18.6 11.5 25.1 4.6 18.9 12.6 6.3 9.8 12.7 3.8 0.0 4.7 5.5 0.0 7.0 4.9 6.2 4.6 3.5 6.7 2.4 9.0 6.8 8.6 6.1 2.8 6.2 10.5 3.5 14.1 6.6 34.7 8.9 9.1 8.0 8.1 11.1 9.8 6.1 15.5 9.7 17.3 9.6 7.5 13.7 19.9 10.8 8.9 2.5 8.8 10.3 16.6 12.5 8.5 10.8 16.0 8.3 13.0 11.4 9.0 17.6 11.0 13.0 14.7 RHBDD2 "NPD007, RHBDL7" ENSG00000005486 "Rhomboid domain containing 2" Q6NTF9 7 75842602-75888926 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045074, HPA051960" Uncertain Enhanced "Golgi apparatus" "Golgi apparatus" "HPA045074: AB_10965705, HPA051960: AB_2681673" "unprognostic (2.75e-1)" "unprognostic (3.89e-2)" "prognostic unfavourable (3.31e-5)" "unprognostic (9.79e-2)" "prognostic unfavourable (1.81e-4)" "unprognostic (2.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.87e-2)" "prognostic favourable (8.68e-6)" "unprognostic (3.73e-1)" "unprognostic (6.53e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-1)" 12.3 50.9 44.3 9.2 64.6 12.1 12.1 14.4 68.3 17.9 11.9 18.5 43.8 18.2 8.5 31.8 14.2 22.6 12.5 14.1 48.5 69.1 18.5 21.7 22.1 8.9 33.6 29.9 12.3 23.6 81.3 56.5 10.6 37.1 15.8 9.1 23.0 22.8 57.3 6.0 14.4 12.5 7.0 16.2 9.5 15.3 15.5 10.7 9.5 34.3 4.2 7.6 10.0 9.6 11.1 13.5 76.4 14.0 13.2 27.4 12.2 7.4 24.6 11.1 22.4 6.5 4.2 4.6 4.5 17.8 10.3 8.7 13.3 20.6 2.8 4.0 8.5 12.2 7.3 5.3 3.2 8.5 14.4 2.5 15.5 12.7 17.9 4.2 23.2 9.2 13.1 11.6 5.2 6.6 5.7 18.3 8.7 49.6 8.0 23.7 10.8 14.1 5.9 7.7 21.4 16.9 13.4 14.7 29.3 16.8 35.7 17.1 23.3 8.0 6.2 16.2 13.5 10.6 9.3 15.2 5.3 4.4 16.1 6.7 19.7 76.4 14.0 17.6 18.9 13.9 16.6 11.1 21.3 16.7 13.5 10.8 18.0 15.3 24.0 13.2 7.9 11.1 27.4 12.2 44.3 64.6 14.4 68.3 48.5 69.1 33.6 29.9 37.1 10.7 RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavourable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" 12.7 3.7 6.2 11.5 9.3 0.3 17.7 3.5 6.2 21.8 10.8 6.1 6.7 5.6 13.0 10.4 17.5 10.6 17.2 15.9 7.0 2.8 8.2 3.8 17.8 4.1 6.9 4.9 18.8 9.6 9.8 4.3 26.5 7.3 19.6 5.5 15.9 20.1 13.5 13.4 22.4 7.5 14.6 5.8 6.1 9.2 7.1 3.1 1.2 11.2 15.7 10.1 16.0 19.4 0.0 0.5 0.0 1.7 0.0 0.4 0.0 4.2 6.9 4.0 9.2 15.7 19.5 13.2 11.8 22.2 8.3 8.0 9.4 15.0 0.2 4.9 12.5 13.6 1.9 7.9 1.4 0.1 2.1 0.1 6.9 2.6 17.6 0.1 7.6 16.2 8.3 21.5 3.6 12.6 1.6 0.2 13.1 23.9 0.0 1.3 3.6 5.9 0.1 4.7 0.3 9.3 4.4 0.1 0.9 3.4 13.1 7.3 20.1 1.5 13.2 13.2 9.3 10.2 3.2 0.1 0.2 0.1 9.2 0.2 20.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.2 9.3 3.5 6.2 7.0 2.8 6.9 4.9 7.3 3.1 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease mutation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavourable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.7 7.6 11.6 29.1 17.5 25.9 11.2 3.2 11.5 6.7 6.8 16.4 1.8 6.3 5.4 5.0 16.7 7.5 11.0 6.0 12.8 7.1 9.5 5.2 17.1 24.5 18.2 3.8 6.3 18.9 4.7 4.4 9.9 15.3 6.6 4.6 7.0 9.4 4.7 8.9 19.4 18.2 6.0 23.4 31.6 8.5 4.0 15.3 3.5 8.9 8.1 26.8 10.7 10.0 12.5 9.3 10.7 12.2 4.5 8.2 6.5 16.4 18.8 0.6 5.3 0.1 0.4 13.8 4.3 12.9 3.8 4.6 5.5 22.1 17.7 14.3 4.9 13.9 3.1 19.3 3.0 3.1 5.8 1.2 1.3 9.0 12.9 0.7 2.7 2.5 10.1 8.5 9.8 9.5 2.2 8.6 2.2 13.4 1.9 2.0 3.2 11.0 4.6 0.1 34.8 8.4 6.0 4.2 6.1 4.2 14.3 18.6 11.8 5.0 14.3 0.3 7.1 0.3 4.8 21.3 10.0 14.9 11.7 5.4 12.8 3.9 11.6 3.7 8.2 12.2 5.7 12.5 2.3 5.8 5.9 7.7 1.4 3.4 10.7 4.5 10.4 9.3 1.2 6.5 11.6 17.5 3.2 11.5 12.8 7.1 18.2 3.8 15.3 15.3 RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675666-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3" "Cell line enhanced" "Detected in many" "HeLa: 9.1;MCF7: 9.6;U-266/70: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 3.4" "Group enriched" "Detected in many" 20 "B-cells: 2.2;NK-cells: 1.3;T-cells: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm Nucleoplasm "HPA030359: , HPA030360: , HPA046593: " "prognostic favourable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" 1.7 6.3 10.0 1.1 8.3 2.3 0.7 21.3 14.5 1.3 2.2 1.3 2.2 5.8 1.3 1.7 1.1 1.0 1.2 2.4 8.4 9.9 3.9 1.2 0.8 1.1 5.5 7.2 0.9 6.2 2.2 4.4 1.1 4.6 1.5 1.1 1.5 6.1 2.6 0.8 3.1 5.9 0.7 2.2 0.6 4.5 2.2 1.9 0.7 0.6 0.6 0.5 0.8 0.5 2.2 0.1 0.0 0.0 1.3 3.4 0.7 1.7 2.3 1.3 2.0 1.0 2.6 6.7 0.8 1.2 0.4 0.1 4.7 1.3 0.7 1.6 0.5 1.2 0.1 0.4 0.0 1.7 8.5 1.0 9.1 1.9 0.9 1.7 1.3 1.8 3.2 0.3 0.0 0.1 1.3 1.3 0.1 9.6 0.4 4.6 1.2 0.7 8.1 1.2 1.7 0.1 1.6 1.6 2.2 1.0 0.5 2.2 3.5 4.8 0.5 2.8 2.6 0.9 0.6 11.7 1.6 2.3 1.0 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 0.3 0.0 0.5 0.5 0.2 0.0 1.3 0.0 0.1 1.2 0.7 10.0 8.3 21.3 14.5 8.4 9.9 5.5 7.2 4.6 1.9 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941799 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 26.0;HaCaT: 13.5;RT4: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043807 Approved "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 1.4 0.0 2.9 6.7 2.7 0.0 1.5 0.4 4.0 5.5 14.9 1.7 0.4 0.7 1.9 0.7 18.9 0.7 6.9 4.9 4.2 2.1 0.5 0.4 2.1 1.5 4.9 0.7 1.2 2.4 0.0 0.4 1.0 1.6 3.1 14.7 0.8 8.2 0.4 0.4 13.4 0.9 0.9 7.9 0.6 12.3 8.4 0.4 1.3 0.4 12.2 16.4 6.9 8.2 1.7 2.1 5.3 1.7 0.9 0.9 0.7 8.0 3.2 0.2 0.1 0.1 1.0 0.9 0.4 0.1 0.6 0.0 0.5 26.0 0.2 1.9 3.7 13.5 0.0 4.8 0.3 0.1 0.1 0.1 2.0 1.7 0.5 0.0 0.3 0.6 0.6 3.9 0.0 0.8 0.0 0.2 0.5 0.0 0.0 0.1 0.2 0.7 0.1 0.1 0.0 0.0 26.1 0.2 0.1 2.8 6.6 0.2 3.4 0.2 0.5 2.9 0.3 0.2 0.2 0.2 0.3 0.3 2.5 0.4 0.1 3.6 1.7 1.1 0.8 1.1 0.4 1.7 0.6 0.5 1.9 1.1 0.7 0.7 5.3 0.9 0.7 2.1 0.9 0.7 2.9 2.7 0.4 1.5 4.2 2.1 4.9 0.7 1.6 0.4 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32266176-32324661 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 5.9;AN3-CA: 4.7;HDLM-2: 8.1;NTERA-2: 8.8;U-2 OS: 6.2" "Cancer enhanced" "Detected in some" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain "HPA059607: " "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 1.0 8.2 6.8 1.2 7.4 0.7 1.1 11.3 23.7 1.4 1.2 2.9 3.3 0.9 2.0 1.9 1.3 4.4 0.9 9.7 10.1 6.6 0.8 0.6 0.7 0.7 9.1 4.6 3.4 1.1 0.6 1.9 1.0 6.7 2.1 1.4 3.9 1.0 5.6 0.6 0.9 0.9 1.8 3.6 0.6 0.9 2.5 4.0 0.0 0.6 0.0 0.8 1.9 1.1 0.8 0.0 0.0 0.0 0.0 0.3 0.3 0.0 5.9 5.9 4.7 0.9 0.0 0.1 0.3 0.6 1.9 2.0 0.1 0.0 0.0 0.4 0.7 0.1 1.6 0.0 0.5 8.1 2.3 1.0 4.0 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.5 0.1 0.2 0.0 8.8 0.0 1.0 0.0 0.0 0.0 3.2 0.1 1.6 0.8 0.1 0.1 0.4 0.1 0.0 0.0 6.2 0.3 3.0 0.0 0.0 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 6.8 7.4 11.3 15.6 10.1 6.6 9.1 4.6 6.7 4.0 SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978105-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 113.9" "Cell line enhanced" "Detected in all" "ASC diff: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: " "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavourable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" 29.5 54.1 14.7 12.6 10.2 17.8 25.8 8.8 14.8 21.5 17.6 12.8 50.1 8.8 17.5 24.1 25.9 14.6 20.7 25.0 10.2 11.8 24.8 8.7 25.6 24.5 12.2 14.3 19.9 9.4 113.9 13.6 7.6 14.2 24.6 9.5 13.4 31.5 37.6 6.4 17.8 15.9 23.2 13.9 22.3 20.8 7.7 10.8 2.4 62.7 14.1 25.3 24.7 20.8 14.1 23.4 60.8 44.8 4.6 3.0 20.3 9.5 5.8 9.1 8.5 79.3 17.8 5.1 4.6 23.2 8.1 16.2 2.7 6.1 12.9 27.1 10.9 9.3 4.3 20.8 8.6 17.4 7.5 3.8 5.9 1.6 18.1 7.9 39.5 21.5 8.9 10.5 8.1 13.5 1.1 46.4 11.6 4.1 3.6 19.8 4.1 8.5 5.0 11.2 8.3 1.8 29.6 2.8 7.1 11.7 8.8 6.9 4.0 20.3 7.2 24.7 6.6 14.5 5.2 52.4 38.3 7.1 17.3 5.6 6.7 0.3 44.8 60.8 3.0 27.1 1.9 12.9 2.1 1.9 23.4 14.1 2.9 2.9 7.3 4.6 25.3 4.5 2.5 20.3 14.7 10.2 8.8 14.8 10.2 11.8 12.2 14.3 14.2 10.8 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" 7400000 "Nuclear membrane" "Golgi apparatus" "HPA047533: " "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favourable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavourable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favourable (2.95e-4)" "unprognostic (7.89e-2)" 65.5 43.6 18.7 23.3 17.3 36.4 42.6 11.2 15.5 44.4 38.5 23.0 38.8 20.7 41.8 57.9 40.3 27.3 33.2 30.8 18.7 18.4 56.5 68.2 44.7 41.1 24.7 12.6 55.7 70.9 21.2 41.7 46.0 18.4 44.4 28.0 28.5 43.5 36.2 51.9 23.3 33.3 39.7 31.5 38.4 29.5 28.2 19.7 33.2 74.6 39.3 32.1 49.8 37.8 29.1 44.3 32.6 48.4 34.3 45.9 46.3 23.6 51.1 37.7 58.3 47.8 59.7 29.0 37.8 44.1 31.1 37.2 54.7 58.7 11.8 24.9 46.5 51.6 52.3 31.7 33.8 28.9 38.6 34.3 58.2 51.3 41.5 25.8 38.9 41.1 39.9 21.4 34.8 43.9 34.1 31.6 41.9 55.5 10.5 56.1 40.1 22.0 13.2 48.8 38.3 69.8 66.3 18.5 41.6 31.4 35.2 85.1 34.4 60.0 29.9 31.5 23.7 26.9 46.0 31.1 58.9 16.6 34.2 45.5 24.6 20.7 43.8 24.1 28.4 47.3 28.5 29.1 35.4 30.4 43.8 26.6 30.2 30.9 32.6 34.3 48.4 44.3 45.9 46.3 18.7 17.3 11.2 15.5 18.7 18.4 24.7 12.6 18.4 19.7 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139477-59158836 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 132.6" "Cell line enhanced" "Detected in many" "HDLM-2: 58.2;Karpas-707: 62.8;RPMI-8226: 127.1;U-266/70: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: " "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 5.9 18.4 30.1 18.6 29.7 11.3 16.0 14.9 25.2 12.2 18.7 24.4 27.8 27.5 9.1 58.0 10.7 9.2 11.1 7.2 27.7 33.9 19.0 66.8 13.0 22.0 41.8 21.3 7.0 96.8 14.6 46.6 8.1 27.1 48.8 16.4 10.0 132.6 34.1 4.3 7.9 21.1 6.6 51.3 23.6 28.4 6.4 25.3 7.3 35.9 8.6 23.4 18.9 5.9 33.6 50.0 10.6 17.6 17.3 34.4 32.6 8.6 10.4 5.7 8.8 3.5 0.6 7.3 7.9 6.7 9.7 5.9 7.3 4.7 19.9 12.4 4.7 9.3 8.9 5.9 5.6 58.2 12.2 6.4 7.3 22.4 10.6 21.0 9.7 2.0 14.1 6.0 16.2 3.2 7.3 62.8 3.4 10.2 8.6 8.4 5.7 6.4 7.9 5.6 127.1 6.3 7.3 26.6 10.5 4.7 19.1 26.6 8.6 15.5 2.5 11.8 4.9 4.1 9.4 64.0 47.1 19.5 11.7 14.3 14.4 10.6 13.1 9.4 25.9 15.5 33.1 33.6 27.3 25.2 13.5 17.4 14.3 19.5 2.0 17.3 17.6 50.0 34.4 32.6 30.1 29.7 14.9 25.2 27.7 33.9 41.8 21.3 27.1 25.3 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "Suppression of tumorigenicity 14" Q9Y5Y6 11 130159562-130210376 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 94.1" "Cell line enhanced" "Detected in some" "CACO-2: 35.7;CAPAN-2: 72.1;HaCaT: 50.5;RPMI-8226: 47.3;SK-BR-3: 33.4;T-47d: 50.5;U-698: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in many" 5 "dendritic cells: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047014 Approved Nucleoplasm,Vesicles 220000 "Nucleoplasm, Vesicles" "HPA047014: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favourable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 10.1 1.8 0.7 21.9 1.8 0.5 5.5 0.8 1.4 8.9 48.6 0.5 23.8 33.8 2.8 16.9 38.9 9.7 32.4 1.1 0.5 0.5 30.5 3.2 9.5 7.5 1.8 0.6 3.6 34.3 8.4 9.5 12.7 1.5 12.1 15.4 0.7 25.1 15.8 0.7 17.8 94.1 1.2 1.8 4.0 16.7 2.1 1.5 5.2 24.0 20.1 28.4 8.3 14.9 3.8 18.2 2.3 2.7 0.0 0.1 0.8 26.2 0.0 0.0 0.1 0.0 0.0 14.3 0.0 0.0 0.0 0.0 35.7 72.1 26.0 2.7 0.0 50.5 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.1 0.2 0.1 0.0 0.0 47.3 4.7 21.5 2.9 0.0 0.2 33.4 0.0 50.5 5.1 0.0 0.0 0.4 0.1 0.1 0.0 0.0 34.4 0.0 8.0 0.0 0.0 2.7 2.3 0.0 1.5 0.1 3.8 0.0 0.0 4.5 2.3 0.0 0.0 0.3 0.0 0.2 18.2 0.0 0.8 0.7 1.8 0.8 1.4 0.5 0.5 1.8 0.6 1.5 1.5 TMPRSS11A ECRG1 ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909385-67964140 "Enzymes, Predicted membrane proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix, uterine: 19.5;esophagus: 48.4;lymphoid tissue: 18.7;tongue: 47.6" "Cell line enhanced" "Detected in single" "Daudi: 1.5" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 47.6 18.7 0.3 8.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11B ENSG00000185873 "Transmembrane serine protease 11B" Q86T26 4 68226653-68245720 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 138.8;lymphoid tissue: 57.0;tongue: 44.0" "Low cell line specificity" "Detected in some" "Group enriched" "Detected in some" 12 "cervical cancer: 2.6;head and neck cancer: 2.6;stomach cancer: 1.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (4.24e-2)" "prognostic favourable (6.91e-4)" "unprognostic (2.92e-1)" "unprognostic (3.96e-1)" 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 11.2 0.1 0.0 0.0 0.1 0.5 0.1 138.8 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 13.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.1 44.0 57.0 0.1 23.2 0.7 0.6 2.4 0.5 0.4 0.7 0.0 0.3 1.4 0.8 0.1 0.1 0.0 0.3 0.3 0.1 0.0 0.3 0.8 0.4 1.3 0.1 0.4 1.0 0.2 0.1 0.0 0.1 1.5 0.8 1.8 2.0 0.1 1.1 1.3 0.5 0.2 0.0 0.1 0.0 0.7 2.0 0.1 0.7 0.5 1.3 0.1 1.0 0.6 0.6 0.5 0.2 1.4 0.8 0.3 0.1 0.2 0.1 0.4 0.2 1.3 1.0 0.3 0.5 0.1 0.2 0.9 0.7 0.3 1.0 0.1 0.3 0.4 0.2 0.4 0.1 0.3 0.3 0.3 0.4 0.0 0.7 0.3 0.7 2.4 0.4 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11D ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884032 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix, uterine: 18.1;esophagus: 41.2;lymphoid tissue: 20.3;tongue: 67.6;vagina: 23.1" "Cell line enhanced" "Detected in single" "RH-30: 1.2" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052834 Uncertain "Intracellular and membrane" "HPA052834: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.6 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 67.6 20.3 0.4 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447449-68497604 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.8;lymphoid tissue: 39.1;tongue: 40.5;vagina: 36.6" "Group enriched" "Detected in some" 6 "HaCaT: 5.8;HBEC3-KT: 2.2" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.8" "Lineage enhanced" "Detected in single" "B-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA051062 Enhanced "Intracellular and membrane" "HPA051062: " "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavourable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 28.9 0.0 0.0 1.2 0.0 1.1 10.5 103.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 1.4 0.0 0.0 13.6 0.5 0.0 1.6 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 40.5 39.1 2.6 36.6 1.8 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 5.8 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11F FLJ16046 ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129880 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 18.3;lymphoid tissue: 11.4;skin 1: 10.9;tongue: 13.1" "Group enriched" "Detected in some" 8 "HEL: 2.4;K-562: 5.4;Karpas-707: 1.6;U-266/70: 1.6" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026911 Uncertain "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.2 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.1 0.0 0.0 1.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 13.1 11.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS12 "CT151, MGC57341" ENSG00000186452 "Transmembrane serine protease 12" Q86WS5 12 50842920-50887884 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 52.7" "Cell line enhanced" "Detected in some" "BEWO: 2.9;Karpas-707: 1.1;NTERA-2: 1.3;SK-BR-3: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (3.03e-2)" "unprognostic (7.25e-3)" "unprognostic (1.70e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-1)" "unprognostic (2.98e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (5.65e-3)" "unprognostic (1.03e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 52.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.6 0.1 0.4 0.3 0.0 0.0 0.7 0.0 0.5 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.0 0.0 0.3 0.4 1.3 0.5 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.6 1.1 0.0 0.1 0.2 0.2 0.3 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.2 0.2 1.3 0.1 0.5 0.2 0.0 0.1 0.1 0.2 0.1 0.0 0.4 0.3 0.3 1.6 0.4 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS13 "MSPL, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900643-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.1;salivary gland: 16.6;skin 1: 26.0" "Cell line enhanced" "Detected in some" "A-431: 7.3;BEWO: 17.5;MCF7: 14.7;SK-BR-3: 25.3;T-47d: 25.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" 0.2 0.3 0.2 0.6 0.2 0.3 6.2 0.2 0.2 5.8 0.2 0.2 0.2 0.2 0.9 0.7 14.8 0.1 0.2 0.2 0.4 0.0 0.7 0.2 4.0 0.7 0.2 0.2 0.3 5.7 0.0 0.5 22.1 0.2 0.9 0.2 0.6 16.6 0.2 0.2 26.0 0.5 0.2 0.2 1.0 0.1 0.3 0.2 0.4 9.5 13.7 10.6 0.3 5.6 1.0 2.6 1.0 0.7 1.9 1.2 0.8 7.3 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 5.6 0.1 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.4 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.0 0.2 0.0 0.0 25.3 0.3 25.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.0 0.6 0.0 0.9 0.7 0.0 1.0 0.1 1.2 1.8 0.5 0.4 0.1 0.0 1.9 0.5 2.6 0.7 0.8 0.2 0.2 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "intestine: 154.6" "Group enriched" "Detected in some" 20 "U-138 MG: 19.8;U-87 MG: 55.3" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "olfactory region: 9.3" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Nucleoli,Plasma membrane" "Plasma membrane" Nucleoli "HPA015611: AB_1855791, HPA034857: , HPA072934: " "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 80.5 0.0 0.0 154.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 42.4 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.5 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.1 0.0 0.3 0.0 0.0 55.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464551-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.6;pancreas: 64.5;prostate: 68.2" "Cell line enhanced" "Detected in some" "CACO-2: 14.6;MCF7: 6.3;RT4: 35.2;SK-BR-3: 7.2;T-47d: 5.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034493, HPA035787" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" "Cell Junctions" Nucleoplasm "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favourable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favourable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.2 0.1 0.2 15.5 0.4 0.0 6.1 0.2 0.5 1.3 38.7 0.4 24.4 17.5 0.5 0.9 10.7 2.2 17.3 0.2 0.3 0.1 19.4 18.4 20.7 0.2 0.2 0.2 0.7 64.5 0.0 1.3 1.0 0.4 68.2 18.5 0.3 52.3 35.7 0.2 2.1 75.6 0.9 0.2 0.3 36.7 0.8 0.3 0.5 19.9 3.9 10.2 5.9 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 14.6 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.1 0.5 1.3 0.0 0.0 0.0 1.4 0.6 35.2 0.0 0.4 0.0 7.2 0.1 5.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 0.2 0.5 0.3 0.1 0.2 0.2 0.4 0.3 TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371837-42396846 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.7" "Group enriched" "Detected in some" 5 "HEL: 18.3;U-266/84: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "MAIT T-cell: 6.3" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Region enriched" "Detected in single" 7 "cerebellum: 0.9" "Not detected" "Not detected" "unprognostic (8.47e-3)" "unprognostic (2.83e-1)" "prognostic unfavourable (3.64e-4)" "unprognostic (2.85e-1)" "unprognostic (2.45e-3)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (8.17e-2)" "unprognostic (9.62e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "prognostic unfavourable (8.24e-4)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" 1.8 0.7 8.6 0.3 7.7 0.3 9.4 0.3 7.1 6.8 0.4 0.0 0.0 1.7 0.9 0.4 0.4 24.7 8.6 0.2 1.8 1.6 3.5 3.5 3.7 0.6 3.7 2.0 2.8 7.4 0.2 5.8 5.7 3.3 0.8 0.4 2.4 12.3 0.6 0.3 0.6 1.3 0.2 0.2 0.6 15.9 0.2 0.8 0.0 9.8 0.2 0.6 1.9 0.0 0.0 0.1 0.7 0.8 0.0 6.3 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.0 0.0 18.3 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.4 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.4 0.0 0.0 9.5 0.4 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.0 0.2 73.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 6.3 0.0 3.5 3.6 0.1 0.0 0.7 1.8 0.7 0.0 0.8 0.0 1.6 1.0 8.6 7.7 0.3 7.1 1.8 1.6 3.7 2.0 3.3 0.8 TMPRSS4 "MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.9;gallbladder: 45.4;lymphoid tissue: 41.0;urinary bladder: 43.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 44.9;HaCaT: 19.2;RPTEC TERT1: 31.5;RT4: 39.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "basophil: 4.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavourable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" 0.3 0.3 0.2 14.2 0.3 0.0 0.3 0.3 0.2 11.4 23.5 0.1 0.0 16.1 3.1 2.8 60.9 0.6 45.4 0.3 0.3 0.3 17.7 0.3 3.2 0.0 0.2 0.0 0.3 0.4 0.0 0.3 0.8 0.1 9.9 26.2 0.2 4.0 0.0 0.3 2.4 27.4 4.2 0.2 0.3 13.7 0.7 0.0 0.6 0.3 13.7 41.0 43.9 22.3 0.5 0.1 4.5 0.7 0.2 0.1 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 44.9 0.0 1.7 0.0 19.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 31.5 39.3 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.5 0.1 0.1 0.9 0.2 0.7 0.1 0.1 0.0 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.0 0.1 0.0 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687546-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.0;salivary gland: 15.0;skeletal muscle: 6.0" "Cell line enhanced" "Detected in some" "AF22: 4.4;CAPAN-2: 7.1;WM-115: 5.8" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 2.1 1.7 10.8 1.0 24.0 3.2 2.2 2.1 14.8 1.2 1.0 21.6 0.0 1.0 1.2 0.9 1.8 1.1 2.2 1.2 11.5 5.7 0.9 0.9 0.9 1.1 11.6 12.7 1.4 1.2 0.6 1.5 1.2 16.5 1.2 1.3 0.9 15.0 1.4 6.0 2.7 0.7 1.2 16.9 1.1 2.4 2.3 8.8 0.0 1.1 0.4 1.3 0.9 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.8 4.4 2.5 0.5 0.4 0.6 1.2 0.5 0.6 0.9 2.5 7.1 0.3 3.2 0.5 0.8 0.4 0.4 0.3 0.5 1.3 1.0 0.6 0.0 0.3 1.0 0.8 0.6 0.6 0.6 1.2 0.8 0.8 0.5 0.9 0.0 0.8 1.2 0.5 0.2 0.9 0.5 0.0 0.7 0.4 0.6 1.0 0.5 0.1 3.5 0.5 0.6 0.5 0.9 1.7 0.6 0.7 0.5 0.2 0.1 0.4 0.9 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.0 2.1 12.3 11.5 5.7 11.6 12.7 16.5 8.8 TMPRSS6 FLJ30744 ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109563 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 59.3" "Group enriched" "Detected in some" 4 "Hep G2: 7.5;SCLC-21H: 12.9" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Region enriched" "Detected in single" 10 "basal ganglia: 1.8" "Cell type enhanced" "Detected in single" "memory CD8 T-cell: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in single" "Region enriched" "Detected in single" 5 "basal ganglia: 2.2" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favourable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" 0.1 0.0 0.1 0.1 1.8 0.0 0.8 0.1 0.1 0.1 0.3 0.1 0.1 1.1 0.1 0.4 0.1 0.2 0.4 0.1 0.1 0.0 0.1 59.3 1.9 0.1 0.1 0.1 0.5 0.9 0.0 5.3 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.1 1.1 0.6 0.1 0.1 0.1 2.3 2.6 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.7 0.1 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.2 0.4 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.8 2.3 0.3 0.1 7.5 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.3 0.0 0.0 0.3 0.1 0.4 0.2 0.3 0.0 0.0 12.9 0.4 0.2 1.0 0.0 0.1 0.0 0.6 0.5 1.6 0.1 0.0 1.5 0.4 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.5 0.2 1.3 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TMPRSS7 ENSG00000176040 "Transmembrane serine protease 7" Q7RTY8 3 112034843-112081269 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 2.2;testis: 5.2" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;hTCEpi: 2.7;RT4: 1.3;U-266/70: 1.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA040630 Uncertain "HPA040630: AB_10796124" "unprognostic (4.02e-2)" "unprognostic (9.87e-2)" "unprognostic (9.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.24e-1)" "unprognostic (4.64e-3)" "unprognostic (6.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.94e-1)" "unprognostic (7.23e-2)" "unprognostic (2.96e-1)" "unprognostic (2.06e-2)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.2 0.0 0.1 0.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.5 0.8 0.0 0.0 0.0 1.0 5.2 0.3 0.0 0.2 0.0 0.8 0.5 2.2 0.3 0.5 0.7 0.1 0.3 0.0 0.7 0.2 0.4 0.1 0.9 0.6 0.7 0.2 0.5 0.6 0.2 0.0 0.0 0.0 1.4 0.0 0.9 0.6 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.1 0.4 0.0 0.8 0.0 0.5 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 2.2 0.3 0.7 0.2 0.2 0.1 0.6 0.3 0.2 0.0 0.8 0.7 0.2 1.7 0.5 0.2 0.5 0.2 0.1 TMPRSS9 ENSG00000178297 "Transmembrane serine protease 9" Q7Z410 19 2389771-2426239 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 6.3;lymphoid tissue: 4.6;testis: 5.9" "Cell line enhanced" "Detected in some" "Karpas-707: 6.1;SK-BR-3: 3.1;U-266/70: 5.4" "Low cancer specificity" "Detected in some" "Cell type enhanced" "Detected in single" "eosinophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Region enhanced" "Detected in single" "basal ganglia: 0.5" "Low region specificity" "Detected in all" HPA051483 Uncertain "HPA051483: " "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (5.62e-3)" "unprognostic (1.86e-1)" "unprognostic (1.54e-2)" "unprognostic (1.87e-3)" "unprognostic (3.30e-1)" "unprognostic (6.44e-2)" "unprognostic (7.29e-2)" "unprognostic (2.07e-1)" "unprognostic (6.30e-2)" "unprognostic (9.20e-3)" "unprognostic (2.28e-3)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (3.07e-3)" "unprognostic (6.73e-2)" 0.1 1.1 0.9 0.4 0.2 2.0 1.3 0.0 0.2 0.0 0.4 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 6.3 0.0 0.1 0.0 0.2 1.2 0.0 0.2 0.1 0.1 0.0 0.5 0.0 1.5 1.8 0.4 0.0 0.0 4.6 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 0.1 1.7 0.3 0.2 0.6 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.6 0.5 0.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.8 0.2 2.1 2.3 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 1.0 6.1 0.0 1.2 0.1 0.4 0.5 0.8 1.1 0.0 0.8 0.0 0.3 0.1 0.2 0.2 3.1 0.1 0.4 1.6 0.4 1.1 0.8 1.1 0.7 5.4 1.3 1.5 0.2 0.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102597003-102679958 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" 410000 "Nuclear bodies, Cytosol" "HPA021069: AB_1858344, HPA049630: " "unprognostic (4.75e-2)" "unprognostic (4.78e-2)" "unprognostic (9.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (4.43e-2)" "unprognostic (2.45e-2)" "unprognostic (8.33e-3)" "unprognostic (5.02e-2)" "unprognostic (1.51e-1)" "unprognostic (3.12e-1)" "unprognostic (2.75e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.95e-2)" "unprognostic (3.43e-3)" 19.9 12.4 10.8 21.4 14.5 24.7 18.1 23.1 18.4 16.8 14.7 12.2 50.3 13.1 20.0 21.8 14.4 16.7 13.5 17.0 11.7 9.7 12.9 22.8 18.4 32.8 11.7 13.8 21.6 16.3 15.7 15.7 19.2 15.3 13.9 21.0 12.9 15.6 34.5 35.7 14.1 17.4 19.2 13.4 20.7 15.4 34.5 14.0 23.8 21.9 16.0 19.7 17.0 16.0 6.0 5.8 9.2 6.9 10.9 12.1 4.7 15.9 6.4 18.5 15.7 12.5 17.3 13.2 16.3 11.9 10.5 13.2 13.5 21.5 17.5 5.6 13.1 15.7 14.3 11.5 19.0 12.2 12.7 33.3 16.8 10.8 10.6 37.6 20.3 13.4 5.2 11.8 15.8 15.0 19.8 19.6 14.8 5.0 17.3 28.2 15.0 8.9 19.2 14.0 15.8 13.6 13.2 17.2 14.1 10.2 17.1 7.3 9.8 42.2 12.0 10.0 7.3 6.4 13.5 19.3 23.3 15.3 16.7 27.2 12.9 9.2 6.0 4.0 9.1 6.9 10.7 6.0 10.3 10.1 5.8 5.5 12.1 11.5 1.3 10.9 5.7 4.6 10.9 4.7 10.8 14.5 23.1 18.4 11.7 9.7 11.7 13.8 15.3 14.0 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 173 "HMC-1: 294.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" "CAB016369: AB_628406, CAB022175: , HPA049153: , HPA049554: " "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favourable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 294.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell line enriched" "Detected in some" 8 "HMC-1: 81.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "HPA049153, HPA049554" Supported "Secreted to blood" 7500000 "HPA049153: , HPA049554: " "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.1 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 48 "HEL: 18.3;HMC-1: 27.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "CAB002215, CAB032871, HPA040182, HPA049554" Supported Uncertain "Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: , HPA049554: " "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.1 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225257 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 16.0" "Group enriched" "Detected in some" 9 "HMC-1: 22.3;MCF7: 7.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060458 Enhanced "HPA060458: " "unprognostic (1.86e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-3)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (6.39e-2)" "prognostic unfavourable (1.76e-8)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.65e-4)" "unprognostic (5.70e-2)" 1.3 0.6 0.4 4.5 0.4 0.0 3.1 0.4 0.4 0.6 14.4 0.4 0.4 14.0 1.2 0.4 0.7 0.5 1.0 0.4 0.4 0.0 0.4 0.4 0.6 0.4 0.4 0.4 2.0 0.4 0.0 3.2 0.4 0.4 1.1 8.8 0.4 0.4 0.4 0.4 1.1 16.0 1.2 0.4 0.4 1.0 1.3 0.4 0.4 0.4 1.1 0.4 1.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin domain containing 1" Q2T9J0 10 70137981-70146676 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;PC-3: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 15.2 8.2 4.7 7.0 6.8 3.0 8.0 6.7 7.3 6.0 6.7 5.9 6.9 10.1 5.3 8.4 13.9 5.4 5.2 3.5 3.7 2.8 7.4 7.4 3.5 7.2 3.7 3.6 5.6 9.0 3.3 4.5 4.7 3.5 6.9 2.7 6.9 8.0 5.7 5.3 12.5 8.5 4.8 4.7 9.0 8.2 40.7 3.4 6.2 8.5 6.6 10.1 6.5 7.6 6.1 1.4 1.2 1.6 2.9 6.3 2.3 9.4 6.7 0.5 4.0 0.7 0.6 2.4 1.2 0.8 1.4 1.3 4.3 6.0 8.4 4.0 0.3 17.7 0.7 2.6 0.3 5.3 6.0 0.5 1.9 2.1 1.6 0.7 0.0 1.2 5.1 1.2 2.1 1.0 0.0 2.6 0.6 4.2 3.2 3.5 2.2 27.2 5.6 1.6 3.7 0.6 1.6 4.9 2.5 4.1 9.3 3.6 6.0 0.7 1.7 1.6 1.1 3.0 5.3 9.6 5.8 4.1 1.9 3.6 1.2 0.0 1.3 1.2 6.3 1.6 4.1 5.1 3.7 4.9 1.4 6.1 5.3 4.4 0.4 2.9 1.1 1.0 4.0 2.3 4.7 6.8 6.7 7.3 3.7 2.8 3.7 3.6 3.5 3.4