Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294034 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5" "Cell line enhanced" "Detected in many" "Karpas-707: 30.6;U-266/70: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 8.8;granulocytes: 5.1;monocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" 72000 Vesicles "Plasma membrane" "HPA036302: , HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.9 14.7 7.1 3.5 8.2 4.5 12.0 12.0 8.2 10.3 15.2 11.7 10.6 8.4 15.5 6.1 4.7 13.1 7.7 17.7 6.4 5.8 18.7 32.5 5.3 2.2 10.1 4.9 28.3 64.5 11.6 11.6 26.2 8.0 10.5 8.9 11.0 12.0 10.6 15.1 7.3 16.0 10.6 6.8 47.3 8.7 6.9 9.7 2.2 17.1 5.0 3.2 11.3 16.0 1.1 8.8 5.1 10.5 0.8 0.7 1.3 3.7 2.1 1.9 2.9 10.6 3.7 6.4 2.1 1.9 1.2 1.2 5.3 4.3 4.7 5.3 3.8 1.0 4.6 0.9 0.7 0.0 3.7 0.0 1.5 11.5 4.6 2.2 3.8 5.7 2.4 0.1 2.8 2.1 5.7 30.6 0.9 1.7 1.6 3.8 1.8 3.3 16.3 1.1 4.1 0.1 15.5 3.7 2.8 3.8 2.0 2.1 0.9 10.8 2.0 2.2 1.4 4.7 2.8 22.6 12.3 10.9 2.6 3.8 0.0 2.0 8.2 5.1 0.2 7.8 0.3 0.8 0.3 0.1 8.8 1.1 0.7 0.1 1.7 0.8 10.5 7.4 0.0 1.3 7.1 8.2 12.0 8.2 6.4 5.8 10.1 4.9 8.0 9.7 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731317-226799759 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.0;naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: " "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.0 9.9 3.1 5.0 2.7 0.6 11.7 9.6 5.4 13.3 14.2 1.4 3.9 4.0 17.2 5.0 3.8 13.9 11.5 6.3 3.9 2.2 5.2 12.0 5.0 2.5 2.3 2.6 21.9 7.1 3.4 2.5 9.1 4.2 9.8 2.9 5.5 3.3 7.5 23.3 5.1 6.5 11.7 2.6 3.3 5.8 2.4 1.7 17.1 23.4 5.6 2.5 14.6 15.8 1.2 0.4 0.0 0.2 0.0 0.3 0.2 3.2 14.7 10.8 0.4 14.9 8.9 0.0 8.8 7.0 11.9 7.7 8.4 8.2 1.3 1.5 6.0 5.6 0.7 8.5 6.8 3.2 0.6 0.0 0.9 3.9 7.4 0.3 0.0 12.3 4.7 9.3 8.5 0.0 1.6 13.1 8.0 12.6 2.7 3.7 4.3 8.2 0.6 14.0 0.1 5.4 10.7 1.9 0.3 2.8 2.0 4.7 7.9 0.1 0.7 15.7 14.4 12.1 8.5 6.1 2.5 1.9 15.5 0.3 4.6 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.1 1.2 0.2 0.1 0.0 0.0 0.0 0.4 0.3 0.2 3.1 2.7 9.6 5.4 3.9 2.2 2.3 2.6 4.2 1.7 INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161341 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 193 "pancreas: 514.0" "Group enriched" "Detected in some" 9 "EFO-21: 52.5;U-2 OS: 68.8;U-698: 21.7" "Cancer enriched" "Detected in single" 7166 "pancreatic cancer: 1751.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "midbrain: 1.7" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" 437220 "CAB000048: , CAB012098: AB_300968, CAB053843: AB_620123, HPA004932: AB_1851816" "unprognostic (7.61e-2)" 0.4 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.7 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 1.4 0.1 0.1 0.1 0.1 0.1 0.1 514.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 2.6 0.1 0.1 0.1 0.1 1.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.8 0.0 5.2 0.0 2.4 21.7 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648971-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.7" "Group enriched" "Detected in many" 5 "granulocytes: 7.7;T-cells: 2.9" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved Approved Vesicles 36000 Vesicles "CAB010268: AB_671792, HPA045563: " "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 8.4 12.7 11.5 5.9 13.5 16.3 18.5 23.0 15.7 15.3 13.4 10.4 22.7 4.2 15.3 16.3 9.2 18.9 7.7 11.6 11.7 7.3 17.0 2.0 11.0 4.9 8.0 11.8 23.2 22.5 4.7 13.8 17.5 9.5 21.7 7.2 16.7 12.5 23.2 9.1 13.0 7.5 18.1 8.0 7.3 10.7 12.0 11.5 10.7 16.1 7.0 5.6 12.8 21.6 1.0 0.4 7.7 0.6 1.0 2.9 0.7 3.3 16.5 11.6 0.2 5.8 4.2 7.7 3.7 7.4 1.2 1.1 7.1 8.8 0.8 10.7 7.2 15.8 5.1 15.0 1.0 0.0 5.2 12.5 18.5 14.2 5.1 6.6 1.3 6.6 7.1 2.1 10.2 4.1 0.6 2.9 5.7 23.4 2.5 4.4 10.8 0.9 4.0 9.0 3.0 3.5 20.3 3.9 17.3 26.7 1.5 14.4 8.1 3.1 11.3 1.1 15.0 3.0 5.8 1.0 4.4 2.7 2.2 4.9 2.8 4.0 0.6 1.8 0.9 0.6 0.6 0.4 0.8 0.3 0.4 1.0 2.9 1.0 7.7 1.0 0.5 0.3 0.0 0.7 11.5 13.5 23.0 15.7 11.7 7.3 8.0 11.8 9.5 11.5 IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752698-109786568 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 70.1" "Cell line enhanced" "Detected in many" "hTERT-HME1: 18.0;SH-SY5Y: 18.9;THP-1: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol Cytosol Aggresome "CAB016944: , HPA054664: " "unprognostic (2.87e-3)" "unprognostic (5.73e-3)" "unprognostic (4.39e-2)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (5.49e-3)" "unprognostic (2.10e-1)" "unprognostic (9.28e-2)" "unprognostic (9.70e-2)" "unprognostic (2.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.09e-2)" "unprognostic (6.21e-3)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (3.17e-2)" "unprognostic (1.24e-1)" 38.9 24.3 27.6 10.9 25.2 70.1 33.5 19.6 30.6 13.5 10.9 13.0 6.7 8.7 14.4 12.2 7.1 7.7 8.4 13.5 23.6 14.6 7.7 24.6 11.6 5.3 24.2 22.1 27.1 7.9 6.1 23.0 13.6 19.5 20.0 7.5 9.3 11.5 12.2 20.9 15.3 9.7 9.7 25.1 9.0 8.3 6.3 21.3 2.0 10.7 4.7 5.3 8.4 17.8 0.5 0.1 6.9 1.4 0.2 0.5 0.2 2.6 3.0 1.9 0.0 16.5 3.3 1.0 2.9 3.4 1.7 1.5 0.2 3.2 0.0 1.8 2.0 1.2 1.0 2.6 2.2 1.0 13.6 1.2 4.3 0.0 16.7 4.7 1.5 6.9 13.9 0.5 18.0 0.6 0.8 0.0 17.0 1.3 0.0 13.9 2.1 0.6 5.9 1.8 1.2 4.9 0.7 2.9 18.9 1.5 0.0 11.6 0.3 28.3 0.0 3.7 0.0 0.2 3.8 0.0 1.3 0.9 2.7 4.6 6.3 2.7 1.4 1.9 0.2 0.3 0.3 0.1 0.4 0.1 0.1 0.5 0.5 0.4 6.9 0.2 0.4 0.1 0.5 0.2 27.6 25.2 19.6 30.6 23.6 14.6 24.2 22.1 19.5 21.3 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 320.7" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 412.2;U-2197: 171.0;U-87 MG: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" 3247666667 5600000000 Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavourable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavourable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavourable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 47.4 1.6 4.4 10.6 2.7 0.0 52.1 2.7 4.1 44.3 21.3 1.7 3.2 6.9 58.4 8.1 11.7 14.9 5.4 41.6 4.4 2.6 11.1 80.4 11.7 12.7 3.7 1.9 49.2 2.2 0.6 19.2 320.7 4.1 22.5 6.1 9.1 6.4 9.3 13.9 23.9 10.2 22.9 3.8 18.7 8.3 12.1 3.1 2.2 5.6 8.6 8.3 32.0 26.3 0.0 28.9 0.0 0.0 0.0 6.0 1.7 9.3 2.8 5.5 0.0 4.2 1.7 0.0 41.2 7.5 3.5 1.9 0.0 7.6 0.0 13.1 412.2 22.6 0.0 0.1 1.4 0.0 0.0 0.0 1.0 0.0 1.1 0.0 0.0 14.4 0.6 0.7 2.6 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.3 0.5 0.0 0.0 3.8 2.6 20.4 0.6 1.6 14.2 0.5 0.7 0.0 0.0 0.0 40.7 0.0 171.0 2.3 0.5 0.0 0.0 88.5 0.0 13.7 0.0 0.0 0.0 5.2 0.0 4.3 0.0 6.0 5.6 0.0 0.0 2.8 4.7 0.0 0.0 0.0 28.9 0.3 1.7 4.4 2.7 2.7 4.1 4.4 2.6 3.7 1.9 4.1 3.1 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215720-68301821 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favourable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 26.2 13.4 26.0 13.0 24.3 51.6 42.3 15.3 50.3 27.1 20.3 12.8 12.8 8.1 41.3 22.1 20.8 33.0 18.1 33.9 24.0 13.4 17.9 46.5 16.3 12.0 22.0 40.8 25.8 6.8 22.3 9.4 15.0 18.2 15.2 10.8 8.7 54.6 16.2 48.9 19.1 16.1 36.3 17.6 18.8 13.1 7.6 23.6 16.2 12.8 8.5 10.8 25.2 24.4 2.2 2.1 10.6 4.1 8.2 14.8 4.0 1.0 2.1 6.3 18.7 71.7 21.0 2.7 6.0 2.8 2.3 2.5 5.2 1.9 5.5 10.3 8.2 2.6 1.7 12.1 2.9 23.0 2.3 6.6 1.7 4.2 24.1 6.7 5.3 22.1 27.6 4.2 22.5 3.0 1.0 4.2 2.1 2.8 16.4 2.6 1.8 1.1 15.4 3.0 4.3 3.0 12.3 1.2 5.7 0.9 1.6 3.9 9.0 4.8 3.6 2.7 2.8 4.5 3.7 4.7 7.0 6.4 2.9 8.5 2.0 10.6 1.2 5.9 9.2 1.7 12.7 1.2 11.5 8.4 2.1 2.2 14.8 10.8 1.5 8.2 4.1 0.9 8.5 4.0 26.0 24.3 15.3 50.3 24.0 13.4 22.0 40.8 18.2 23.6 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574076 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Intracellular and membrane" 140000 "HPA063478: " "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favourable (3.69e-4)" "prognostic favourable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 9.8 13.1 6.9 11.7 8.8 6.0 19.8 8.6 9.4 10.5 9.9 6.5 17.5 7.4 10.2 15.9 13.0 8.4 9.6 13.6 5.8 5.3 13.3 21.3 7.9 9.2 8.9 5.1 7.7 15.7 19.4 11.1 9.4 7.6 11.6 10.0 10.5 11.0 17.2 31.1 45.2 10.7 14.3 8.8 9.9 10.3 18.1 7.5 13.5 12.0 13.9 10.7 11.5 9.8 7.4 11.3 3.8 13.7 7.7 10.6 5.5 12.2 18.1 14.1 29.0 13.8 11.6 7.8 10.8 25.7 11.4 9.7 18.4 14.5 17.3 16.0 15.8 15.8 18.6 11.9 7.5 20.7 11.4 8.6 15.1 16.1 12.1 26.2 13.6 8.2 11.6 13.4 19.4 19.2 16.0 12.3 12.9 8.2 8.7 10.3 11.2 7.2 12.1 13.2 11.0 16.8 22.9 6.6 9.2 14.6 10.5 9.5 15.0 7.4 17.8 7.4 8.4 7.7 13.9 11.3 14.1 18.5 10.8 21.0 5.1 2.3 8.2 3.8 6.7 11.4 5.9 7.4 7.9 6.5 11.3 5.3 6.0 6.4 0.5 7.7 13.7 4.4 10.6 5.5 6.9 8.8 8.6 9.4 5.8 5.3 8.9 5.1 7.6 7.5 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2149603 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 330.5" "Cell line enhanced" "Detected in some" "CACO-2: 112.8;Hep G2: 77.4;LHCN-M2: 44.5;RH-30: 55.3;SH-SY5Y: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" 609000000 1700000000 Vesicles "Nucleoplasm, Cytosol" "HPA007556: , HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favourable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 16.6 8.0 1.3 4.5 2.0 0.5 23.3 2.3 1.9 23.4 5.0 3.4 4.7 1.0 9.9 32.0 5.2 17.2 4.5 20.5 1.5 1.6 8.1 39.7 1.9 1.1 3.5 1.6 20.4 5.5 0.7 5.0 330.5 7.6 10.4 1.0 33.2 2.6 6.7 21.9 1.7 2.3 7.5 17.0 2.0 3.2 12.4 0.2 1.8 2.6 14.5 1.8 15.2 14.1 0.0 0.1 0.5 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 14.9 0.1 0.4 0.0 112.8 0.0 0.0 1.1 0.0 0.0 0.1 0.9 1.0 0.0 0.0 0.0 0.0 77.4 19.8 0.0 0.0 24.1 0.0 0.1 0.0 0.1 0.0 0.0 44.5 0.2 0.0 0.1 0.1 0.2 0.0 55.3 0.1 0.0 0.1 4.4 67.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 1.3 2.0 2.3 1.4 1.5 1.6 3.5 1.6 7.6 0.2 IGF1 "IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 21.3;HDLM-2: 27.7;K-562: 12.4;Karpas-707: 6.6;U-266/70: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 2.4;naive B-cell: 4.5" "Lineage enriched" "Detected in single" 9 "B-cells: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048946 Approved "Secreted to blood" 175950000 410000000 "HPA048946: " "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favourable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 33.4 3.6 0.8 10.7 1.4 0.3 23.0 0.6 2.1 46.6 6.7 0.6 20.6 2.2 35.0 58.3 16.1 8.1 8.8 17.4 1.5 1.0 3.9 32.8 7.6 13.3 0.9 0.4 17.6 3.2 1.2 1.2 13.5 1.9 57.2 2.8 3.7 5.4 32.0 11.9 3.2 3.5 29.4 1.0 4.9 5.9 19.0 0.2 1.5 29.3 11.6 2.2 21.2 15.3 4.5 0.2 0.5 0.1 0.2 0.1 0.8 0.2 0.0 0.0 0.0 21.3 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.4 6.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.1 2.4 0.1 0.1 0.0 4.5 0.1 0.1 0.5 0.2 0.1 0.2 0.0 0.8 0.8 1.4 0.6 2.1 1.5 1.0 0.9 0.4 1.9 0.2 IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108732482-108736409 "Cancer-related genes, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 56.0" "Cell line enhanced" "Detected in some" "HEK 293: 13.6;NTERA-2: 1.7;RT4: 4.0;WM-115: 3.0" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 7 "hypothalamus: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 12.8;hypothalamus: 52.4" "Group enriched" "Detected in some" 6 "basal ganglia: 21.5;hypothalamus: 55.3" HPA017372 Uncertain "HPA017372: " "unprognostic (3.74e-3)" "unprognostic (3.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (9.28e-4)" "unprognostic (8.71e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.6 1.9 0.0 0.1 0.3 0.1 2.6 0.3 0.3 0.5 0.0 0.0 0.3 4.6 0.0 0.0 0.1 0.0 0.5 0.1 9.5 0.0 0.0 56.0 0.1 0.6 0.2 0.0 2.7 0.0 0.5 0.0 0.6 0.0 1.0 0.2 0.1 0.5 0.1 0.5 5.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.3 4.6 0.5 0.1 0.6 0.5 IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888357-45893668 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "liver: 157.6;placenta: 292.3" "Group enriched" "Detected in some" 8 "Hep G2: 17.6;U-2197: 28.8;U-87 MG: 49.8" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" 28130000 22000000 "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavourable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavourable (6.90e-11)" "prognostic unfavourable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" 0.4 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 10.7 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.2 157.6 0.1 0.0 0.1 0.0 9.3 0.0 0.0 0.2 292.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 17.6 0.1 0.3 0.0 0.0 0.2 3.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443461-40457731 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 370.8" "Cell line enhanced" "Detected in many" "A549: 109.4;ASC diff: 82.6;ASC TERT1: 81.0;BJ: 87.8;BJ hTERT+: 90.4;HSkMC: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 12.6;NK-cell: 20.5" "Group enriched" "Detected in many" 5 "NK-cells: 20.5;T-cells: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" 227300000 500000000 "HPA066240: " "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favourable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favourable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavourable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" 79.7 23.3 2.5 36.8 5.2 0.0 198.7 1.8 3.1 115.0 57.1 3.2 41.1 9.9 88.8 126.5 67.7 67.4 117.5 119.1 2.2 1.8 72.3 255.6 88.2 101.4 3.7 2.3 370.8 21.5 6.5 19.4 99.8 5.1 66.7 17.0 46.2 24.4 38.6 36.3 22.3 36.8 80.4 6.4 68.1 38.7 53.2 2.3 4.2 81.0 50.4 22.5 89.9 123.9 3.6 0.1 0.0 0.0 20.5 12.6 0.9 0.0 109.4 5.6 0.0 82.6 81.0 0.1 87.8 90.4 16.8 13.1 4.8 1.4 0.0 47.6 41.7 0.9 1.8 0.5 7.6 0.3 0.1 0.3 8.0 7.2 51.8 0.2 0.0 172.1 0.3 22.5 3.2 29.1 1.7 0.0 24.1 3.3 0.0 20.2 3.1 14.8 5.4 0.1 0.1 0.7 3.4 1.5 4.4 39.7 0.1 1.3 40.5 2.0 43.8 23.4 1.2 73.9 0.0 0.0 0.0 0.1 13.9 0.8 6.0 0.0 0.0 0.0 1.8 0.0 12.6 0.4 3.3 4.4 0.0 3.6 0.2 0.4 0.0 20.5 0.0 0.1 0.0 0.9 2.5 5.2 1.8 3.1 2.2 1.8 3.7 2.3 5.1 2.3 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695525 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 245.3" "Cell line enhanced" "Detected in many" "BJ: 77.9;BJ hTERT+: 207.2;T-47d: 50.4;U-138 MG: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" 109650000 330000000 "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: , HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavourable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 47.3 23.4 6.2 19.2 6.3 0.1 41.3 3.6 6.5 191.7 23.1 19.7 15.8 3.9 94.6 91.0 30.0 96.9 21.4 16.9 8.2 2.4 34.8 7.8 9.3 14.5 12.1 7.4 245.3 3.5 6.5 37.7 32.7 7.0 31.4 7.9 188.5 12.0 15.1 47.0 13.5 14.2 71.8 7.4 7.6 36.9 51.7 12.0 1.5 130.1 34.5 17.6 28.8 45.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 20.1 0.0 23.2 0.7 0.0 77.9 207.2 10.4 1.0 0.0 0.0 0.0 0.3 0.2 0.0 2.4 0.0 0.5 0.0 0.7 20.0 0.4 0.0 10.1 0.0 0.1 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.1 0.2 0.3 0.0 0.0 0.1 6.7 23.1 1.3 0.8 1.3 9.6 0.0 50.4 0.0 7.5 68.7 4.2 10.4 3.7 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 6.2 6.3 3.6 6.5 8.2 2.4 12.1 7.4 7.0 12.0 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 126.5" "Cell line enhanced" "Detected in many" "CACO-2: 14.9;HMC-1: 26.0;SK-MEL-30: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 7.6;eosinophil: 2.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, HPA043084" Enhanced Supported "Focal adhesion sites,Centrosome" "Focal adhesion sites" Centrosome "HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favourable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 95.0 6.4 23.0 16.4 21.6 1.8 23.5 16.8 22.5 14.9 70.2 18.7 22.1 8.1 41.8 12.5 45.0 25.1 28.9 83.7 20.9 8.3 5.9 14.7 8.7 1.4 13.4 14.1 9.8 7.3 17.5 3.5 9.9 19.2 42.0 20.0 6.4 7.2 65.7 46.4 6.3 15.5 126.5 20.6 2.9 40.0 5.5 19.3 0.0 4.0 12.7 1.2 63.9 31.4 0.1 0.0 7.6 1.2 0.6 1.0 0.2 0.7 0.6 6.3 1.6 2.3 0.1 0.9 0.2 0.0 0.2 0.0 14.9 5.6 0.0 1.2 0.1 0.3 1.1 0.2 0.1 1.7 2.3 3.6 0.2 8.9 0.8 0.0 26.0 0.4 0.2 0.3 0.1 2.6 5.9 1.2 0.6 0.4 0.0 0.3 2.9 1.4 0.5 2.1 0.2 7.0 9.8 2.7 2.0 0.9 0.3 22.3 1.2 0.2 0.2 0.0 2.2 0.1 1.2 0.8 0.2 0.1 2.7 0.2 6.3 7.6 0.2 2.2 0.7 1.2 1.0 0.1 0.3 0.4 0.0 0.1 0.3 0.1 0.2 0.6 0.2 0.0 0.5 0.2 23.0 21.6 16.8 20.7 20.9 8.3 13.4 14.1 19.2 19.3 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 165.3;pancreas: 228.7" "Cell line enhanced" "Detected in many" "ASC diff: 138.4;HMC-1: 322.9;NB-4: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" 539805000 1000000000 "Endoplasmic reticulum" "HPA077723: " "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavourable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavourable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 21.7 6.4 0.9 13.7 2.8 2.6 17.5 1.0 10.4 11.9 12.6 4.5 20.6 11.4 28.7 37.7 26.4 19.4 11.8 29.6 1.5 0.9 21.3 165.3 8.7 3.8 1.4 3.4 35.7 228.7 0.8 8.2 32.0 7.6 25.7 5.2 8.0 9.1 32.6 5.3 3.1 7.8 7.5 1.8 46.7 50.2 13.7 1.0 12.1 8.4 29.3 12.9 23.4 11.4 0.0 0.3 0.0 0.4 2.0 0.8 1.3 0.0 3.2 25.3 24.6 138.4 42.3 0.5 7.7 3.8 0.3 0.0 0.0 0.0 0.0 10.8 0.0 0.7 9.0 9.6 0.0 0.0 5.2 5.5 0.0 1.5 3.4 2.3 322.9 14.1 1.0 0.1 0.4 0.0 0.2 0.7 0.1 6.2 9.6 66.6 27.3 0.3 8.3 0.5 0.1 0.1 7.1 5.3 27.9 0.0 0.2 0.1 20.7 4.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.5 0.3 10.6 29.5 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 1.3 0.9 2.8 1.0 10.4 1.5 0.9 1.4 3.4 7.6 1.0 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859018 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.5;brain: 5.9;kidney: 8.3" "Group enriched" "Detected in some" 7 "SCLC-21H: 5.4;SH-SY5Y: 18.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA025285 Uncertain "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.9 5.5 0.0 0.3 5.9 0.1 0.8 1.9 1.4 1.9 0.1 0.0 0.0 0.1 2.7 0.1 0.1 0.6 0.3 1.9 0.5 1.3 8.3 0.1 0.1 0.4 0.8 0.6 0.3 0.9 0.1 1.7 0.4 5.6 2.7 0.1 2.1 0.6 0.5 0.4 0.1 0.2 0.3 0.0 0.2 3.0 4.2 0.4 0.3 0.3 0.0 0.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 1.4 0.5 1.3 0.8 0.6 5.6 0.4 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase, non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" 11000 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 22.1 22.2 12.1 31.9 16.0 35.3 17.9 12.9 16.6 18.2 17.8 18.8 14.2 10.5 20.0 16.6 23.2 17.1 18.0 20.5 15.8 9.0 43.8 16.7 42.7 36.1 14.1 14.1 21.8 12.2 31.2 18.8 28.3 18.7 20.0 14.8 21.0 16.3 15.0 41.0 18.6 21.9 16.9 15.8 45.3 17.5 23.5 13.3 26.9 15.7 13.9 42.8 20.0 18.4 15.9 9.4 18.8 16.4 3.9 10.7 6.4 20.7 10.5 12.7 8.7 8.3 11.5 18.0 14.0 13.3 41.1 15.0 30.8 43.8 10.3 24.9 12.9 18.5 10.1 40.1 26.2 15.3 9.0 14.6 10.2 16.2 16.6 15.1 20.0 13.4 28.2 18.5 22.8 23.6 25.3 9.5 22.3 11.5 16.2 12.0 6.7 14.4 14.4 14.8 9.8 23.7 15.6 10.2 11.7 20.1 25.5 22.6 16.5 16.2 35.0 35.9 14.4 16.1 17.3 10.4 8.4 12.6 22.5 10.3 13.2 12.0 5.6 18.8 10.7 9.5 7.9 15.9 9.0 8.2 5.5 13.7 7.7 8.3 12.2 3.9 16.4 9.4 7.1 6.4 12.1 16.0 12.9 16.6 15.8 9.0 14.1 14.1 18.7 13.3 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Predicted secreted proteins" Hormone "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 234.1" "Cell line enhanced" "Detected in some" "Karpas-707: 8.8;PC-3: 4.0;SCLC-21H: 8.0;SH-SY5Y: 7.2" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA028615 Enhanced "Secreted to blood" 566000 "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.1 0.4 0.1 1.1 0.2 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.1 0.3 0.1 1.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.1 0.1 9.6 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 1.1 0.1 234.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 2.4 0.3 5.7 1.2 1.3 2.9 1.1 0.3 1.0 0.2 0.7 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 1.7 0.2 2.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.3 0.0 0.1 1.9 1.3 0.9 0.0 0.0 0.0 0.1 8.8 0.0 1.5 0.3 1.5 0.0 4.0 1.3 0.0 0.2 0.2 0.5 8.0 7.2 0.1 2.4 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.7 3.1 0.2 0.1 2.0 0.0 0.8 0.5 0.0 1.8 1.2 1.8 0.3 2.4 2.3 0.3 2.4 2.1 2.9 5.7 1.3 0.3 0.3 2.0 1.1 0.1 0.2 0.2 0.6 0.1 0.0 0.1 0.1 0.1 0.1 INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "placenta: 88.0" "Cell line enriched" "Detected in some" 11 "A549: 23.1" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 1.8 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 88.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 23.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281667-7288257 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 37.2;skeletal muscle: 76.8;tongue: 33.5" "Cell line enriched" "Detected in some" 4 "Hep G2: 10.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Lineage enhanced" "Detected in single" "dendritic cells: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB016544 Enhanced "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" 9.9 1.4 0.6 1.8 0.7 1.1 6.4 0.0 0.6 4.7 13.9 0.2 4.0 1.0 4.2 7.0 11.8 3.2 2.9 37.2 0.3 0.1 0.7 1.2 0.5 0.7 0.8 0.1 1.9 0.4 2.9 1.2 0.8 0.5 6.3 1.4 6.4 4.6 3.8 76.8 0.9 3.3 23.5 0.2 0.2 3.8 1.5 0.0 0.0 1.2 33.5 1.6 18.6 1.6 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 1.8 1.5 0.7 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.1 1.2 0.2 0.0 0.8 0.3 0.2 0.1 0.0 1.8 0.0 0.3 10.6 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.4 0.0 0.2 0.7 0.1 2.4 0.6 0.8 0.0 0.1 0.0 1.0 0.0 1.3 0.0 0.8 0.1 0.0 0.0 1.5 0.0 0.2 0.6 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.7 0.0 0.6 0.3 0.1 0.8 0.1 0.5 0.0 ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476879 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0;pancreas: 25.5;pituitary gland: 26.6" "Group enriched" "Detected in some" 5 "A549: 4.6;AN3-CA: 3.7;SCLC-21H: 6.5" "Cancer enriched" "Detected in some" 9 "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" Nucleoli "Golgi apparatus, Cytosol" "CAB011451: , HPA042318: " "unprognostic (4.30e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-2)" "unprognostic (9.48e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.53e-3)" "unprognostic (6.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (2.22e-2)" "unprognostic (1.96e-2)" "unprognostic (6.88e-5)" "unprognostic (2.72e-2)" "unprognostic (1.85e-1)" 1.3 6.7 4.4 0.8 6.1 0.9 4.0 28.0 12.3 3.0 1.3 2.6 7.7 1.9 3.1 3.7 0.8 1.2 0.9 2.9 5.1 4.8 1.0 0.8 2.9 0.8 3.6 7.2 0.9 25.5 1.0 26.6 1.6 8.5 2.8 1.3 0.7 0.9 8.5 2.3 1.1 1.5 1.3 4.0 0.9 3.5 1.1 2.3 0.0 6.2 0.0 0.8 0.7 0.8 0.1 0.0 0.5 0.0 0.1 0.2 0.0 0.0 4.6 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 6.5 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.0 4.4 6.1 28.0 12.3 5.1 4.8 3.6 7.2 8.5 2.3 IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969099-160113507 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 59.6;hTERT-HME1: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Enhanced "Golgi apparatus,Vesicles" 150000000 "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavourable (3.01e-4)" "prognostic unfavourable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (6.08e-4)" 28.0 22.2 6.8 13.5 8.1 16.7 39.4 6.4 8.2 14.9 17.3 9.5 13.0 9.4 19.6 16.0 16.7 13.1 17.9 27.9 6.7 6.2 20.6 26.6 32.6 44.7 12.3 3.6 18.0 19.6 23.5 13.6 15.5 10.0 14.1 13.3 13.9 18.2 13.5 62.0 15.9 15.4 16.5 7.6 30.2 14.4 13.8 9.0 37.9 18.5 17.3 14.1 16.3 26.9 0.4 2.9 13.3 2.0 1.0 3.6 0.9 7.7 7.0 12.4 17.4 45.3 25.0 16.8 12.2 26.4 10.1 17.4 10.6 12.2 3.2 13.7 13.4 10.4 9.3 59.6 17.0 16.8 6.6 1.4 12.2 19.1 26.8 7.4 12.1 19.9 19.1 21.0 60.7 6.5 13.9 17.4 15.9 5.7 3.4 7.4 5.5 7.5 8.0 8.5 16.3 14.3 7.8 4.1 9.1 16.5 14.8 16.5 6.2 21.0 9.8 9.8 10.3 21.1 22.3 10.3 14.4 3.3 18.9 10.2 15.1 0.1 2.0 1.1 3.6 0.8 1.4 0.3 1.2 1.7 0.3 0.4 1.0 2.4 13.3 1.0 1.4 2.9 0.7 0.9 6.8 8.1 6.4 8.2 6.7 6.2 12.3 3.6 10.0 9.0 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 27.8;BJ: 74.4;fHDF/TERT166: 26.5;HaCaT: 44.2;U-87 MG: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 12.5;non-classical monocyte: 7.1" "Group enriched" "Detected in many" 6 "granulocytes: 12.5;monocytes: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008005 Uncertain "Secreted to blood" 199425000 320000000 "HPA008005: AB_1851499" "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavourable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 60.2 15.9 0.9 6.7 1.4 1.2 61.0 0.3 4.7 70.2 15.2 0.8 34.9 5.2 20.7 78.5 47.0 37.6 14.7 27.5 0.7 0.8 6.4 2.6 12.5 3.3 5.9 2.9 37.5 3.9 1.7 19.6 12.5 6.1 29.4 3.6 41.5 6.1 23.5 18.3 6.5 8.9 52.6 26.1 8.0 12.6 36.0 0.0 0.2 15.1 55.8 7.6 58.0 90.5 0.0 0.7 12.5 7.1 0.0 1.7 0.4 15.5 9.8 0.0 6.2 8.4 27.8 0.0 74.4 17.3 2.9 2.0 0.9 12.9 0.0 7.7 26.5 44.2 0.0 1.7 0.4 0.0 0.2 0.1 1.7 1.5 4.2 0.0 0.0 11.2 0.0 1.9 0.2 0.8 0.0 0.1 0.8 0.0 0.5 0.1 0.4 21.2 0.1 0.5 0.2 0.1 0.0 0.0 0.7 22.9 0.0 0.6 0.3 0.0 17.6 3.6 4.6 6.5 1.3 0.4 0.3 0.0 31.0 0.2 1.9 0.0 0.0 12.5 0.1 2.1 0.8 0.0 0.3 1.0 0.7 0.0 0.1 1.7 0.0 0.0 7.1 0.0 0.0 0.4 0.9 1.4 0.3 1.7 0.7 0.8 5.9 2.9 6.1 0.0 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Cell line enhanced" "Detected in many" "BEWO: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favourable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.5 4.8 1.7 8.9 0.0 0.0 23.5 0.5 0.2 5.6 0.3 12.1 16.4 0.0 14.9 1.9 13.2 10.1 12.5 4.0 0.5 11.2 0.0 7.7 16.1 1.6 0.0 5.8 0.3 7.5 0.0 4.3 0.0 3.3 0.1 0.1 9.2 0.4 0.0 3.4 11.7 0.0 0.0 2.6 9.6 7.9 12.3 9.9 6.1 13.7 2.6 9.6 2.0 0.0 0.0 7.1 0.1 0.0 3.5 0.6 0.1 0.6 0.1 8.5 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44144271-44198170 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 46.8" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 12.0" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 4.4;naive CD4 T-cell: 4.8" "Group enriched" "Detected in many" 17 "B-cells: 4.4;T-cells: 4.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 1.1 0.5 3.2 0.7 2.8 0.0 0.7 9.5 3.7 1.4 1.4 1.3 0.7 0.3 1.5 1.5 0.7 2.3 0.9 7.1 2.1 7.5 0.7 8.7 0.7 0.7 2.9 1.2 2.2 2.9 0.0 46.8 3.3 1.6 0.8 0.5 0.8 0.7 1.6 0.7 1.2 0.7 0.7 1.7 0.7 0.9 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.9 4.4 0.2 0.0 0.0 0.0 4.8 0.7 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.6 0.3 0.0 0.0 0.0 0.1 0.8 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.6 0.9 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.6 4.4 1.6 0.4 0.2 0.7 4.8 0.9 0.0 0.0 0.0 0.0 0.0 0.7 3.2 2.8 9.5 2.4 2.1 7.5 2.9 1.2 1.6 0.7 INSL5 ENSG00000172410 "Insulin like 5" Q9Y5Q6 1 66797741-66801256 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "intestine: 52.9" "Cell line enhanced" "Detected in some" "HEK 293: 1.4;hTCEpi: 1.1" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;prostate cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030100, CAB033849" Enhanced "Secreted to blood" 38500000 "CAB033849: AB_2264904, HPA030100: AB_10601915" "unprognostic (2.48e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (2.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.62e-2)" "unprognostic (7.53e-2)" 0.0 0.0 0.8 0.0 1.3 0.0 0.0 0.1 1.0 0.0 30.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.1 1.8 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.2 52.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INSL6 RIF1 ENSG00000120210 "Insulin like 6" Q9Y581 9 5131979-5185668 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 22.3" "Cell line enhanced" "Detected in some" "HEL: 1.1;HL-60: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021364 Enhanced "Secreted to blood" "HPA021364: AB_1851807" "unprognostic (3.85e-4)" "unprognostic (7.41e-4)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (2.22e-1)" "unprognostic (6.92e-2)" "unprognostic (2.31e-2)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.52e-3)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 22.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 PDX1 "IDX-1, IPF1, MODY4, PDX-1, STF-1" ENSG00000139515 "Pancreatic and duodenal homeobox 1" P52945 13 27920020-27926231 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "gallbladder: 10.4;intestine: 33.0;pancreas: 24.2" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;CACO-2: 2.0;CAPAN-2: 2.4;HDLM-2: 6.8;HEK 293: 4.1;HeLa: 10.3" "Group enriched" "Detected in many" 11 "colorectal cancer: 8.4;liver cancer: 1.9;pancreatic cancer: 8.6;stomach cancer: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025873, HPA059146" Enhanced Supported Nucleoplasm Nucleoplasm "CAB025873: , HPA059146: " "unprognostic (2.79e-2)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (6.84e-2)" "unprognostic (3.89e-2)" "unprognostic (6.75e-3)" "unprognostic (7.10e-3)" "unprognostic (3.83e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 33.0 0.0 0.0 31.1 0.1 0.0 0.1 0.1 10.4 0.1 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.0 0.1 24.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 17.6 0.0 0.2 0.1 4.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 6.8 4.1 0.0 10.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 22.6;LHCN-M2: 13.5;U-138 MG: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "NK-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" 2500000 "CAB032904: AB_2099635, HPA062066: " "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 17.2 2.1 0.5 1.9 0.5 0.0 30.5 0.6 0.4 8.5 2.8 1.6 8.3 1.1 25.7 7.1 1.5 6.4 2.6 1.9 0.5 0.7 10.9 19.4 2.0 0.7 1.1 0.0 7.3 17.5 22.2 27.0 28.9 0.8 3.3 1.2 13.4 5.4 6.5 2.1 1.7 2.6 6.8 2.0 1.2 1.7 4.6 0.3 2.0 13.2 6.9 1.4 3.2 7.7 0.6 2.2 1.4 0.3 4.6 1.7 0.1 0.0 0.8 0.8 0.0 22.6 3.5 0.0 5.8 6.0 2.3 6.3 2.5 0.7 0.0 0.5 3.7 0.0 0.8 0.1 9.7 0.2 1.1 0.0 0.7 7.5 0.7 0.0 2.7 5.8 0.2 6.2 0.2 2.7 0.0 1.2 13.5 1.6 0.0 0.0 5.1 0.8 0.0 6.6 0.1 0.1 0.3 2.2 0.0 0.1 0.8 2.6 2.5 0.0 1.8 18.1 0.6 1.2 5.7 2.2 0.0 0.0 8.3 0.0 2.2 1.4 0.2 0.3 0.3 0.2 1.7 0.3 0.3 0.3 2.2 0.6 0.3 0.3 1.0 4.6 0.3 0.3 0.2 0.1 0.5 0.5 0.6 0.4 0.5 0.7 1.1 0.0 0.8 0.3 GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285675-10292947 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 21.8;stomach 1: 64.9" "Cell line enhanced" "Detected in many" "Karpas-707: 16.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 6.2;classical monocyte: 6.0;eosinophil: 6.0;myeloid DC: 21.8;neutrophil: 13.5;plasmacytoid DC: 15.0" "Group enriched" "Detected in many" 7 "dendritic cells: 21.8;granulocytes: 13.5;monocytes: 6.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" 2584407 69000 "CAB022731: , HPA014246: AB_1849659" "unprognostic (1.74e-2)" "unprognostic (3.01e-4)" "unprognostic (3.75e-1)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-3)" "unprognostic (2.12e-1)" "unprognostic (1.06e-3)" "unprognostic (3.85e-1)" "unprognostic (5.45e-3)" "unprognostic (1.54e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-3)" "unprognostic (4.52e-2)" "unprognostic (8.56e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-4)" 1.2 0.6 1.8 4.2 1.7 1.5 0.6 0.7 1.5 0.6 1.2 1.8 2.2 7.4 0.9 2.3 1.1 1.0 1.7 1.3 1.6 0.7 0.8 0.8 1.8 14.5 0.9 0.4 1.0 1.7 0.2 0.8 0.2 1.1 1.2 0.2 0.7 3.2 0.1 0.7 0.8 1.4 0.3 0.9 4.9 64.9 0.7 1.3 1.7 1.2 0.0 4.3 0.7 0.5 0.8 21.8 13.5 6.0 2.1 0.1 2.0 0.7 0.3 3.0 2.2 2.1 0.0 5.4 2.7 0.0 0.8 0.2 3.1 0.5 1.6 1.0 0.1 0.4 0.0 0.7 0.0 0.5 3.2 3.3 1.7 6.7 0.0 3.4 6.0 0.4 0.0 0.1 0.1 0.6 1.4 16.2 0.0 0.7 1.3 4.7 1.4 5.9 0.9 0.3 0.9 0.0 3.5 2.1 0.3 1.8 1.2 0.1 1.7 4.2 2.8 1.4 0.8 1.2 1.8 1.9 2.7 3.4 0.4 3.9 0.6 6.2 6.0 6.0 0.1 2.8 0.0 0.8 0.1 0.0 21.8 0.5 0.1 0.0 13.5 2.1 0.2 15.0 0.1 2.0 1.8 1.7 0.7 1.5 1.6 0.7 0.9 0.4 1.1 1.3 GIP ENSG00000159224 "Gastric inhibitory polypeptide" P09681 17 48958554-48968596 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 64 "intestine: 87.5" "Group enriched" "Detected in some" 4 "A549: 8.6;BEWO: 7.8;Hep G2: 12.3" "Cancer enriched" "Detected in some" 63 "testis cancer: 74.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016729, HPA021612" Enhanced "Secreted to blood" 33915 "CAB016729: , HPA021612: AB_1849506" "unprognostic (2.95e-1)" "unprognostic (2.70e-3)" "unprognostic (4.42e-2)" "unprognostic (1.82e-1)" 0.2 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 87.5 0.0 0.0 75.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 61.7 0.0 0.1 0.1 0.2 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.4 0.7 7.8 0.3 0.0 0.1 0.0 2.2 0.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 1.5 12.3 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668244-45683724 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3;stomach 1: 26.1" "Cell line enhanced" "Detected in some" "HDLM-2: 7.9;HMC-1: 17.9;SCLC-21H: 11.9;U-266/70: 14.7" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB022710 Uncertain "CAB022710: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" 8.0 0.4 2.3 4.5 8.4 2.4 6.6 1.8 10.5 2.9 4.5 9.4 0.1 4.3 0.7 1.5 1.8 10.0 1.8 12.3 3.7 2.6 1.7 0.5 4.8 3.6 21.3 1.4 1.0 8.5 9.0 2.0 0.4 6.3 5.3 5.8 2.6 5.8 0.6 0.4 3.3 3.6 0.5 4.6 4.1 26.1 0.4 16.2 0.2 1.8 0.8 4.4 3.0 3.3 2.3 1.2 2.5 0.8 4.1 2.3 0.7 0.7 0.4 1.2 0.7 0.5 0.0 0.2 0.9 0.7 0.1 0.7 0.4 3.4 1.5 0.5 0.6 1.8 0.3 0.1 0.1 7.9 0.3 1.4 0.8 0.3 0.1 0.4 17.9 0.0 0.3 0.2 0.2 0.1 3.6 1.9 0.0 0.2 0.1 1.1 0.1 0.9 0.5 0.3 3.5 0.4 0.9 11.9 1.1 0.1 0.8 0.1 1.7 2.5 0.3 0.0 0.5 0.3 0.3 14.7 0.2 0.3 0.5 1.4 0.3 2.5 0.7 2.0 2.3 0.8 0.8 0.9 0.9 1.6 0.9 2.3 1.1 1.8 2.2 4.1 0.5 1.2 1.8 0.7 2.3 8.4 1.8 10.5 3.7 2.6 21.3 1.4 6.3 16.2 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 61.6" "Cell line enhanced" "Detected in many" "Daudi: 10.2;U-698: 10.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Region enriched" "Detected in many" 4 "cerebellum: 8.5" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" 102626666667 3700000000 "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favourable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 2.2 0.4 0.8 0.6 1.2 0.3 0.6 8.5 1.8 0.6 0.6 0.6 0.6 0.1 0.8 0.6 0.6 0.4 0.6 0.6 0.6 1.9 0.6 61.6 0.6 0.6 0.7 0.6 0.7 0.6 1.5 1.3 0.6 0.6 1.0 0.1 0.6 0.6 3.3 0.7 4.8 0.6 0.8 0.6 0.6 0.3 0.8 0.6 6.6 1.6 0.6 0.7 1.0 1.0 1.1 1.6 0.4 0.2 0.1 1.8 0.0 0.7 1.3 1.2 1.8 0.0 0.1 3.0 0.1 0.3 0.4 0.3 5.2 0.1 10.2 1.2 0.2 0.0 1.7 0.3 0.2 1.3 3.4 1.4 1.3 4.3 0.0 1.8 0.2 0.1 0.2 0.1 0.0 0.0 0.6 0.5 0.3 0.7 1.0 0.6 3.9 0.5 2.0 0.3 0.1 0.4 5.1 3.3 3.4 1.1 0.1 0.5 0.5 0.5 0.1 1.2 1.3 0.1 1.4 3.0 4.7 10.4 0.1 0.5 0.5 0.4 0.2 0.1 0.4 0.1 1.4 0.6 0.3 0.2 0.0 1.1 0.3 1.8 0.4 0.1 0.1 1.6 0.2 0.0 0.8 1.2 8.5 1.8 0.6 1.9 0.7 0.6 0.6 0.6 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 65.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 11.4;eosinophil: 3.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019423, HPA027502, HPA031818" Approved Supported Vesicles Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: " "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 14.3 14.6 14.7 4.9 26.7 6.5 18.8 22.0 20.9 9.7 10.5 14.6 2.0 12.3 8.9 8.0 7.3 9.0 15.6 19.1 13.8 14.8 19.8 15.6 8.3 4.3 19.8 10.7 6.5 65.8 6.0 21.5 10.6 20.9 10.6 5.1 16.5 7.0 11.7 35.7 3.7 8.4 13.0 9.9 15.9 7.2 11.4 16.9 0.4 18.3 4.2 3.2 12.7 17.3 0.0 0.1 11.4 0.2 0.0 0.4 0.1 0.1 10.6 17.4 7.0 8.2 6.3 9.2 4.3 3.7 8.3 10.1 6.4 0.1 0.2 7.6 5.4 1.0 17.9 4.5 4.1 0.1 7.2 18.3 10.8 4.6 17.4 11.4 28.3 16.3 7.1 12.8 12.7 21.2 34.5 0.2 6.3 1.2 2.0 15.4 19.0 18.4 5.3 0.0 0.1 5.5 4.2 7.6 0.0 0.5 2.7 22.7 9.2 23.2 25.9 7.4 10.1 15.0 16.2 0.7 0.2 0.1 23.4 10.4 24.9 11.4 0.1 3.5 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.1 14.7 26.7 22.0 20.9 13.8 14.8 19.8 10.7 20.9 16.9 IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 107.6" "Cell line enhanced" "Detected in some" "Hep G2: 5.2;T-47d: 2.1;U-266/70: 5.1" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040692, HPA040948" Supported "Secreted to blood" 14650000000 44000000000 "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavourable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favourable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" 0.1 0.0 0.1 0.1 0.2 0.2 0.1 0.8 0.2 0.1 0.4 0.1 0.1 0.2 0.2 0.1 0.1 0.2 7.4 0.1 0.1 0.2 0.2 107.6 0.4 0.1 0.1 0.1 0.1 0.8 0.0 0.2 0.1 0.4 0.1 0.0 1.4 0.6 0.1 0.2 0.2 0.1 0.1 0.3 0.1 5.0 0.5 0.1 1.7 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 5.2 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.9 1.0 0.0 1.2 0.2 0.5 0.2 0.0 1.3 0.5 1.5 0.0 0.0 0.4 0.3 0.3 0.0 0.7 2.1 0.2 0.2 0.4 1.4 0.2 0.2 5.1 1.8 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.2 0.1 0.2 0.1 0.1 0.4 0.1 INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavourable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavourable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavourable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" 12.3 8.2 14.3 7.1 16.5 3.2 13.5 24.4 22.5 10.0 9.6 8.9 7.8 11.6 12.1 16.8 8.1 8.3 9.4 11.0 12.2 10.6 16.0 38.6 12.9 10.2 12.0 13.1 11.8 14.5 16.9 15.8 11.0 17.5 11.8 8.3 8.9 9.4 10.1 8.8 12.1 14.7 10.1 13.9 14.1 13.5 7.3 11.6 18.5 13.2 1.8 9.6 10.0 9.8 11.8 11.4 17.5 17.6 15.4 15.4 9.2 23.4 4.2 6.3 2.7 16.2 8.0 6.9 6.7 7.2 5.3 9.4 3.9 22.5 4.6 22.4 8.4 8.7 4.7 11.1 10.0 8.6 5.8 4.4 5.4 26.6 6.3 5.4 7.1 12.7 10.1 4.8 11.4 12.4 2.3 8.6 8.7 2.5 6.9 7.3 3.1 5.8 4.5 5.5 5.0 12.1 7.3 5.1 6.7 3.9 6.9 3.8 3.5 5.4 13.2 6.7 4.9 6.1 3.4 15.9 8.5 4.1 13.7 4.4 4.4 10.2 10.3 17.5 11.9 15.2 13.9 11.8 13.0 11.4 11.4 10.8 14.2 15.4 10.8 15.4 17.6 10.6 11.6 9.2 14.3 16.5 24.4 22.5 12.2 10.6 12.0 13.1 17.5 11.6 ISL1 "Isl-1, ISLET1" ENSG00000016082 "ISL LIM homeobox 1" P61371 5 51383391-51394738 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 30.3" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 80.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 4.1" "Group enriched" "Detected in some" 5 "basal ganglia: 4.0;hypothalamus: 5.5;pons and medulla: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basal ganglia: 13.8;hypothalamus: 17.5;thalamus: 6.5" "Group enriched" "Detected in some" 12 "basal ganglia: 8.5;hypothalamus: 8.6" HPA057416 Approved Approved Nucleoplasm Nucleoplasm "HPA057416: " "unprognostic (4.97e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-1)" "unprognostic (2.41e-3)" "unprognostic (5.52e-2)" "unprognostic (6.79e-2)" "unprognostic (9.21e-2)" "unprognostic (9.42e-2)" "unprognostic (5.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (9.11e-3)" "unprognostic (4.39e-3)" 2.2 1.5 0.0 0.0 4.0 0.0 0.1 0.0 0.2 14.4 1.6 0.0 4.2 2.3 1.3 0.5 0.2 0.0 0.2 0.0 0.0 5.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.8 10.0 2.0 13.2 2.5 6.4 1.0 30.3 0.1 1.1 0.7 0.6 0.1 0.0 10.7 1.6 0.7 3.1 0.3 0.2 0.4 2.4 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.6 1.2 0.9 0.0 0.0 1.9 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.8 0.0 0.0 0.0 5.1 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 4.0 0.0 0.2 0.0 5.5 0.0 0.0 2.0 0.7 KCNJ11 "BIR, Kir6.2" ENSG00000187486 "Potassium voltage-gated channel subfamily J member 11" Q14654 11 17385859-17389331 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 63.1" "Cell line enhanced" "Detected in many" "Daudi: 7.1;HEK 293: 13.4;MCF7: 10.7;SCLC-21H: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048891 Approved "HPA048891: " "unprognostic (1.95e-2)" "unprognostic (6.18e-3)" "unprognostic (7.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (4.81e-5)" "unprognostic (1.83e-3)" "unprognostic (5.45e-2)" "unprognostic (8.09e-3)" "unprognostic (3.72e-3)" "unprognostic (9.23e-3)" "prognostic favourable (1.56e-4)" "unprognostic (4.05e-2)" "unprognostic (2.10e-2)" "unprognostic (1.67e-1)" "unprognostic (4.75e-2)" 2.5 1.1 2.9 1.0 7.8 0.8 2.7 13.6 7.8 1.0 1.1 0.7 4.9 1.4 1.1 2.1 1.7 1.1 1.1 6.2 3.5 2.4 1.3 0.9 1.3 1.2 2.7 5.2 0.8 8.7 2.7 3.3 0.7 3.5 2.5 1.0 0.1 1.2 7.6 63.1 1.0 1.1 0.8 1.7 1.0 4.6 0.8 1.9 0.0 4.1 4.5 1.0 0.9 1.1 0.8 0.4 1.4 0.3 0.8 0.4 0.4 1.5 2.3 0.3 4.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 2.5 0.2 7.1 0.2 0.0 0.3 4.8 0.1 0.3 1.6 13.4 3.6 0.9 0.8 0.1 0.4 0.3 0.1 0.3 0.0 0.1 0.0 3.7 3.8 0.0 10.7 0.7 0.1 1.0 0.3 1.4 1.7 2.0 0.4 0.9 9.1 0.8 0.0 3.5 0.0 4.6 0.2 0.0 0.0 1.2 0.0 0.1 0.2 6.0 0.9 0.0 1.0 0.0 1.4 0.3 0.2 0.4 0.3 0.3 0.7 0.4 0.4 0.1 0.8 0.4 0.4 1.3 0.8 0.1 0.4 0.3 0.4 2.9 7.8 13.6 7.8 3.5 2.4 2.7 5.2 3.5 1.9 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241284-128257628 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "adipose tissue: 85.2;breast: 63.7;placenta: 24.3" "Group enriched" "Detected in some" 9 "BEWO: 6.8;HSkMC: 2.8" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "neutrophil: 3.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB010490 Approved "Secreted to blood" 26000000 "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 85.2 0.3 0.0 1.5 0.0 0.0 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.7 0.0 0.0 0.1 0.0 0.4 2.0 0.0 0.0 0.1 0.7 0.0 0.0 24.3 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.1 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.5 2.1 0.4 0.4 3.8 0.5 0.5 0.3 0.2 0.0 0.2 0.2 0.4 0.3 0.0 6.8 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.1 0.0 0.2 0.3 0.5 0.2 0.2 0.1 0.3 0.4 0.2 0.4 0.9 0.5 0.3 0.3 0.3 0.2 0.2 0.2 0.2 0.1 0.4 0.2 0.3 3.8 0.5 0.4 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564413 "Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease mutation, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 109.4" "Group enriched" "Detected in some" 32 "Hep G2: 17.9;HHSteC: 10.8;RPTEC TERT1: 29.0" "Group enriched" "Detected in some" 11 "liver cancer: 18.7;renal cancer: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047699 Approved Nucleoplasm Nucleoplasm "HPA047699: AB_10965320" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.77e-3)" 0.1 11.3 0.1 1.4 0.4 0.0 0.2 0.1 0.2 0.2 5.8 0.4 0.1 11.3 0.1 0.4 0.1 0.1 7.0 0.1 0.1 0.0 25.0 109.4 0.6 2.4 0.1 0.1 7.7 2.7 0.0 2.9 0.2 0.3 0.5 0.4 0.6 0.1 0.1 0.1 0.0 19.5 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.3 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.2 0.1 0.0 0.1 0.1 0.3 0.1 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" 160000 Nucleoli "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 34.8 33.3 24.3 23.0 35.4 34.6 28.8 42.4 46.3 33.4 25.2 33.1 13.5 36.9 22.1 39.2 20.9 31.2 37.6 55.7 28.0 25.7 53.7 31.0 18.1 35.4 43.0 34.3 28.0 37.9 35.9 51.1 27.6 40.7 13.0 32.2 25.2 30.2 20.9 29.4 21.8 31.1 35.9 21.2 30.8 39.2 16.9 20.8 40.8 31.3 26.0 36.0 29.9 33.6 39.4 35.3 23.4 37.1 25.2 41.5 36.9 32.7 30.2 36.8 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 37.1" "Group enriched" "Detected in some" 34 "U-266/70: 29.8;U-266/84: 20.8" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA076165 Enhanced "HPA076165: " "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" 0.1 0.0 0.1 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.4 0.1 0.1 0.1 0.1 0.1 0.1 37.1 0.0 0.3 0.1 0.1 0.1 0.0 5.0 6.4 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.6 2.1 0.1 0.1 0.1 0.1 0.1 0.5 0.1 0.1 0.5 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 29.8 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837002 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 49.7;SK-BR-3: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.7" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Golgi apparatus,Cytosol" Cytosol "Golgi apparatus" "CAB005406: AB_2194226, HPA043343: , HPA043878: " "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favourable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favourable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" 34.0 78.2 16.4 9.3 17.9 14.8 15.5 5.8 22.3 15.7 13.8 31.9 30.4 28.9 8.6 23.4 20.5 15.7 17.6 10.2 13.5 10.3 9.0 49.9 11.9 14.4 20.3 16.7 20.5 7.7 9.6 12.5 16.0 11.8 18.0 6.4 15.1 72.7 33.0 16.8 14.5 27.4 7.1 13.1 7.3 13.6 16.8 16.2 15.2 9.5 13.6 13.8 11.9 15.0 0.6 0.4 4.7 0.8 0.4 2.2 0.5 13.7 32.5 4.0 25.0 8.2 15.2 7.0 5.1 16.2 4.4 10.8 6.6 26.9 8.6 4.8 4.0 39.3 4.6 13.6 1.1 5.3 2.0 4.7 27.0 6.9 10.3 0.6 9.1 11.8 5.8 6.2 3.8 5.0 9.1 31.1 1.0 34.0 11.4 7.9 5.4 6.5 8.1 2.9 49.7 3.6 7.2 4.8 19.9 6.0 48.2 14.3 16.3 9.1 5.7 2.4 12.0 5.7 3.2 9.1 0.8 3.9 14.0 6.8 12.4 0.0 0.8 0.4 1.8 0.5 0.4 0.6 0.8 0.3 0.4 0.4 1.6 2.2 4.7 0.4 0.6 0.3 0.2 0.5 16.4 17.9 5.8 22.3 13.5 10.3 20.3 16.7 11.8 16.2 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492812-164621848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 17.7" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 10.5;RPTEC TERT1: 8.7;TIME: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: " "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 1.6 2.9 1.0 1.2 1.5 0.0 6.0 0.7 3.6 0.8 1.2 0.0 1.1 1.2 0.6 7.5 1.7 0.5 0.3 10.8 5.7 1.1 8.3 17.7 0.7 0.1 0.9 2.0 2.4 6.0 0.0 1.8 2.2 1.4 0.8 0.4 1.2 1.0 0.5 3.2 0.5 0.8 0.6 0.6 0.6 1.1 3.1 0.4 0.0 5.5 3.0 0.1 0.6 1.1 0.0 0.0 0.4 0.1 0.0 0.0 3.0 0.9 5.5 0.4 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 2.4 0.6 0.0 3.4 0.0 0.4 0.9 1.6 0.3 0.0 4.8 0.0 0.3 1.3 0.1 0.0 0.0 0.4 1.0 2.0 0.0 10.5 0.0 0.1 1.7 2.2 0.0 0.0 2.1 1.4 0.0 0.0 0.1 8.7 0.4 3.3 0.4 0.0 0.3 0.0 0.6 0.0 13.2 0.2 1.4 0.0 0.1 0.5 0.1 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.0 1.0 1.5 0.7 3.6 5.7 1.1 0.9 2.0 1.4 0.4 IGF2BP1 IMP-1 ENSG00000159217 "Insulin like growth factor 2 mRNA binding protein 1" Q9NZI8 17 48997412-49055650 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "placenta: 17.6;testis: 17.8" "Cell line enhanced" "Detected in many" "AF22: 35.9;CACO-2: 56.5;Hep G2: 26.5;K-562: 28.6;NTERA-2: 28.7;REH: 32.7" "Cancer enriched" "Detected in many" 16 "testis cancer: 28.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021367, HPA062273" Enhanced Supported Cytosol Cytosol "HPA021367: AB_1851480, HPA062273: AB_2684733" "unprognostic (6.79e-4)" "unprognostic (2.76e-1)" "unprognostic (4.86e-3)" "unprognostic (2.30e-6)" "unprognostic (1.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.80e-2)" "unprognostic (1.01e-2)" "unprognostic (9.55e-3)" "unprognostic (2.58e-1)" "unprognostic (2.86e-2)" "unprognostic (5.91e-2)" "unprognostic (2.80e-6)" "unprognostic (2.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-3)" "unprognostic (1.47e-1)" 0.1 0.1 0.0 0.9 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.1 0.3 0.5 0.1 0.3 0.1 0.1 0.0 0.1 17.6 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 17.8 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 35.9 0.0 1.3 1.9 25.7 2.0 0.0 2.9 4.9 56.5 0.9 2.9 0.2 0.2 0.0 22.1 0.0 5.2 0.0 13.0 21.4 7.7 26.5 1.7 11.3 5.7 2.6 0.0 0.7 0.0 6.0 28.6 0.0 4.0 0.2 0.0 9.5 28.7 0.0 32.7 11.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.8 0.0 3.1 0.1 0.0 0.3 3.0 0.0 0.0 0.0 19.3 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.3 0.2 0.0 IGF2BP3 "CT98, IMP-3, IMP3" ENSG00000136231 "Insulin like growth factor 2 mRNA binding protein 3" O00425 7 23310209-23470467 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 74.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 52.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002037, HPA076951" Enhanced Supported Cytosol Cytosol "HPA002037: AB_1851483, HPA076951: " "unprognostic (5.72e-2)" "unprognostic (3.12e-1)" "unprognostic (7.25e-2)" "unprognostic (3.56e-3)" "unprognostic (1.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-3)" "unprognostic (3.18e-2)" "unprognostic (2.60e-3)" "unprognostic (3.67e-1)" "unprognostic (1.02e-5)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (1.43e-1)" "unprognostic (7.95e-2)" "unprognostic (2.87e-4)" "unprognostic (7.51e-3)" 0.4 0.2 0.3 0.9 0.2 0.3 0.2 0.2 0.3 0.4 0.3 0.4 0.1 0.0 0.2 1.3 4.8 0.7 0.1 0.5 0.3 0.2 0.2 0.3 1.2 3.4 0.2 0.0 0.2 1.5 0.0 0.2 74.0 0.7 0.2 0.0 0.3 0.7 0.1 0.2 0.2 0.3 0.0 1.2 1.0 0.2 6.5 0.0 11.4 0.6 0.2 6.0 0.2 0.6 1.2 0.4 1.5 1.5 0.0 0.2 3.0 14.5 4.3 32.7 9.7 5.2 13.8 20.0 2.4 11.0 6.1 7.6 13.8 11.6 11.0 13.2 6.5 9.6 14.1 10.8 10.8 1.7 5.6 5.8 11.7 11.5 16.1 10.5 4.1 14.1 7.6 4.7 2.0 52.3 26.4 0.0 14.8 0.0 6.4 7.1 26.1 13.4 9.9 10.9 14.1 12.1 1.3 8.6 18.8 1.4 0.1 12.2 0.0 2.0 21.0 5.9 0.3 12.8 6.3 0.0 4.6 17.3 23.5 11.8 22.6 0.0 1.5 0.0 0.1 0.8 0.0 1.2 0.0 0.0 0.4 0.9 0.2 0.0 1.5 0.0 0.0 0.0 0.0 3.0 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.0 0.7 0.0 IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 82.3;BJ hTERT+: 77.0;EFO-21: 52.8;RPTEC TERT1: 82.7;TIME: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 15.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" 30300000 240000000 "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" 95.8 46.5 15.1 38.7 23.7 8.5 65.3 5.6 19.2 73.0 47.8 33.1 79.6 22.7 95.2 164.5 50.5 66.3 241.7 121.0 20.4 14.2 187.5 35.5 55.4 109.0 23.9 24.1 53.0 45.6 12.3 29.5 30.4 91.2 78.1 19.0 126.9 22.2 151.6 30.5 21.1 27.0 119.9 21.9 91.7 32.6 68.0 15.7 3.9 128.9 41.2 18.1 96.8 85.3 0.0 8.4 15.5 3.2 8.7 0.1 1.1 0.1 0.5 0.1 0.0 16.7 6.3 0.5 82.3 77.0 7.2 2.3 0.3 0.0 0.0 52.8 3.9 8.2 0.0 13.2 1.9 0.1 0.6 0.2 9.7 0.0 25.8 1.9 2.1 29.0 6.7 11.7 3.2 16.5 0.0 0.1 17.0 0.0 0.0 8.6 0.7 0.1 1.5 0.0 0.3 82.7 0.0 0.1 0.2 15.4 1.1 0.0 0.2 7.5 119.3 7.4 5.6 0.9 13.3 5.0 0.0 0.1 19.4 6.8 0.2 1.6 3.0 15.5 0.1 3.1 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.1 0.2 8.7 3.2 0.3 0.1 1.1 15.1 23.7 5.6 19.0 20.4 14.2 23.9 24.1 91.2 15.7 PHIP "BRWD2, DCAF14, FLJ20705, ndrp, WDR11" ENSG00000146247 "Pleckstrin homology domain interacting protein" Q8WWQ0 6 78935867-79078236 "Predicted intracellular proteins" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019140, HPA019838" Approved Supported Nucleoplasm Nucleoplasm "HPA019140: , HPA019838: " "unprognostic (1.58e-1)" "unprognostic (1.60e-1)" "unprognostic (9.43e-2)" "unprognostic (8.47e-3)" "unprognostic (1.05e-1)" "unprognostic (2.01e-3)" "unprognostic (3.50e-3)" "unprognostic (5.03e-2)" "unprognostic (4.03e-2)" "unprognostic (6.40e-3)" "unprognostic (1.72e-1)" "unprognostic (1.05e-1)" "prognostic unfavourable (1.71e-5)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.55e-2)" 14.7 9.6 13.3 14.9 16.9 40.2 19.4 30.1 14.6 19.1 13.9 11.8 15.0 9.4 18.1 14.1 11.6 16.1 12.3 12.2 11.0 9.7 10.4 7.9 15.4 16.8 15.8 11.0 19.8 15.5 20.6 28.4 14.2 12.8 14.7 12.8 11.0 15.6 18.3 16.6 14.1 13.8 17.1 13.7 14.9 12.9 10.2 17.9 27.8 13.4 8.8 14.4 17.1 22.6 8.3 6.2 17.3 6.1 5.1 7.3 2.2 8.9 7.3 17.5 17.0 6.7 9.7 10.2 9.7 7.7 8.3 10.6 9.0 5.6 14.9 7.7 6.0 8.3 13.1 6.1 14.2 21.4 9.5 16.7 13.8 6.6 3.1 18.5 10.7 5.9 5.5 10.0 10.1 8.7 16.7 14.5 8.0 6.0 7.1 13.3 11.0 8.0 12.6 22.4 6.4 8.9 12.2 17.2 10.9 13.0 9.9 6.1 7.7 24.8 10.2 9.7 6.9 4.6 15.9 9.9 9.7 8.5 4.1 12.0 14.4 10.2 5.0 8.4 5.6 3.3 6.0 6.8 6.6 6.1 3.3 8.3 7.3 5.8 17.3 5.1 6.1 6.2 5.4 2.2 13.3 16.9 30.1 14.6 11.0 9.7 15.8 11.0 12.8 17.9 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase, receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.6;pancreas: 28.9;pituitary gland: 43.4" "Group enriched" "Detected in some" 8 "U-2 OS: 19.8;U-87 MG: 73.7" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA007152: , HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavourable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 1.7 22.3 19.3 4.7 35.7 1.7 1.3 17.3 89.6 1.2 2.4 2.5 0.0 2.5 1.5 1.2 1.5 1.3 1.5 1.4 21.6 40.1 1.5 1.2 1.4 1.3 14.4 19.8 1.3 28.9 1.2 43.4 1.4 22.0 1.4 1.9 3.1 1.2 1.3 1.2 2.0 2.5 2.4 3.5 1.3 6.0 1.4 2.1 0.0 1.5 0.0 1.2 2.7 0.0 0.1 0.3 0.2 0.0 0.0 0.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 2.5 0.0 6.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 4.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.2 73.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.6 3.7 19.3 35.7 17.3 54.0 21.6 40.1 14.4 19.8 22.0 2.1 TBC1D4 "AS160, DKFZp779C0666, KIAA0603" ENSG00000136111 "TBC1 domain family member 4" O60343 13 75284665-75482114 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "GTPase activation" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 36.9;HUVEC TERT2: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 17.4" "Group enriched" "Detected in many" 5 "dendritic cells: 7.2;T-cells: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040145, HPA059885" Approved Supported Cytosol Cytosol "HPA040145: , HPA059885: " "unprognostic (5.44e-3)" "unprognostic (5.23e-1)" "unprognostic (9.85e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-2)" "unprognostic (9.54e-3)" "unprognostic (1.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.87e-1)" "unprognostic (5.02e-2)" "unprognostic (7.53e-2)" "unprognostic (2.64e-1)" "prognostic favourable (1.07e-11)" "unprognostic (6.40e-2)" "unprognostic (3.16e-1)" "unprognostic (8.88e-2)" "unprognostic (3.45e-1)" 12.0 43.9 6.7 6.7 7.0 1.2 17.5 9.3 10.7 6.9 5.7 4.6 4.2 1.9 5.4 10.1 6.1 5.9 8.5 25.5 8.0 4.1 15.6 5.3 8.5 14.9 5.4 7.0 22.5 8.5 9.5 4.2 9.5 11.1 7.4 4.9 2.0 20.8 2.4 40.1 10.8 6.3 4.7 4.8 9.6 6.1 3.3 4.4 1.1 17.7 17.3 14.8 4.7 8.7 0.5 7.2 2.6 0.3 0.3 17.4 1.8 5.5 6.5 4.1 0.2 9.7 10.5 5.3 4.8 2.5 3.9 4.3 36.9 6.8 1.1 1.1 6.8 5.2 10.4 4.8 4.1 18.3 10.5 18.0 8.8 11.1 2.4 8.5 0.2 11.4 8.9 4.3 10.2 27.3 5.0 0.6 4.4 2.6 12.4 1.5 5.8 3.9 11.2 3.9 6.5 3.8 4.0 7.6 2.3 2.1 6.5 3.5 2.2 0.2 11.4 4.4 5.5 2.3 5.6 0.3 0.0 0.1 7.9 8.0 6.5 2.6 0.3 0.0 0.5 0.1 0.0 0.5 8.6 1.8 0.4 0.4 8.0 3.7 0.3 0.3 0.1 7.2 17.4 1.8 6.7 7.0 9.3 10.7 8.0 4.1 5.4 7.0 11.1 4.4 ADRA2A "ADRA2, ADRA2R, ADRAR" ENSG00000150594 "Adrenoceptor alpha 2A" P08913 10 111077163-111080907 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 84.9" "Cell line enhanced" "Detected in some" "ASC diff: 8.0;ASC TERT1: 9.9;HEL: 14.5;HeLa: 7.8;HSkMC: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (3.87e-2)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "prognostic favourable (8.06e-4)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-1)" "unprognostic (4.64e-3)" "unprognostic (5.86e-2)" "unprognostic (5.63e-2)" "unprognostic (3.08e-6)" "unprognostic (1.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-3)" 29.9 1.3 1.4 8.0 1.8 0.2 25.4 4.3 8.1 28.2 7.5 0.7 3.0 8.5 12.4 3.9 2.1 2.6 84.9 5.6 1.7 4.0 3.8 1.1 2.8 18.8 1.5 2.3 15.5 26.2 1.5 1.7 3.4 3.8 10.4 3.5 2.2 4.8 7.4 1.5 6.8 4.9 5.7 1.1 32.2 3.5 3.5 0.0 0.0 5.9 7.1 16.6 9.8 15.9 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 8.0 9.9 0.0 0.0 0.0 0.8 1.9 0.0 0.0 0.0 0.1 4.4 0.0 0.0 0.0 0.8 0.0 0.0 14.5 7.8 0.0 0.0 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 1.4 1.8 4.3 8.1 1.7 4.0 1.5 2.3 3.8 0.0 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: " "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.4 55.4 21.1 21.7 26.3 32.2 11.7 15.0 22.2 31.1 27.8 24.3 20.9 22.9 13.4 33.1 9.8 23.4 31.3 20.1 21.9 26.7 15.0 35.1 15.3 16.5 17.2 18.1 29.7 18.8 21.1 20.1 6.7 19.3 24.0 17.3 18.7 27.3 8.4 11.4 14.9 18.2 11.5 16.5 24.2 36.8 29.1 17.8 15.4 26.4 12.5 20.8 22.2 6.7 19.0 18.8 17.0 23.5 22.4 19.2 18.8 18.6 20.4 15.5 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 BAIAP2 "BAP2, IRSp53" ENSG00000175866 "BAI1 associated protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavourable (7.58e-6)" 10.1 10.9 29.0 4.1 37.4 1.7 11.5 19.6 45.3 14.6 11.8 11.4 18.0 4.3 10.1 26.0 45.9 20.6 17.6 8.7 22.1 10.6 20.6 26.3 20.0 3.6 7.3 24.3 5.1 7.6 8.4 19.2 17.0 9.8 25.7 7.1 11.8 17.0 17.1 3.9 52.6 4.9 10.8 5.4 6.2 20.1 9.2 12.3 2.1 10.2 20.1 20.2 11.1 20.5 0.1 15.4 4.8 7.8 1.3 2.7 2.3 29.9 13.8 8.9 11.5 7.1 9.5 10.3 12.4 8.1 11.2 5.0 18.7 15.2 0.1 9.0 10.9 29.2 8.1 14.2 4.3 0.1 10.2 6.1 12.2 13.9 6.6 0.0 8.9 4.0 16.8 9.2 4.9 6.0 7.8 0.2 6.4 15.9 1.2 6.7 3.7 12.2 1.8 2.2 24.6 34.3 10.5 11.7 12.8 19.8 28.7 33.3 25.2 6.9 7.3 26.2 24.9 4.3 13.1 0.4 0.1 0.4 22.8 1.0 5.6 0.0 5.9 0.4 2.7 7.8 0.9 0.1 1.0 0.9 8.3 0.1 1.2 1.5 4.8 1.3 7.2 15.4 0.4 2.3 29.0 37.4 19.6 45.3 22.1 10.6 7.3 24.3 9.8 12.3 BAIAP2L1 IRTKS ENSG00000006453 "BAI1 associated protein 2 like 1" Q9UHR4 7 98291651-98401068 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA019484: AB_1845265, HPA021257: AB_1845266, HPA023874: AB_1845267, HPA029503: AB_10602330" "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.00e-1)" "unprognostic (2.95e-1)" "unprognostic (2.80e-2)" "unprognostic (8.31e-3)" "unprognostic (4.56e-2)" "unprognostic (1.34e-2)" "unprognostic (9.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" 4.7 11.2 1.3 16.9 1.1 0.0 10.3 0.3 0.9 6.1 27.3 1.1 10.8 16.2 3.6 4.7 17.9 6.8 29.6 2.1 0.7 0.6 8.9 31.0 15.4 0.9 0.8 0.2 2.6 47.4 4.7 16.9 17.0 1.2 15.2 12.5 6.5 14.7 12.3 3.3 11.3 34.0 3.4 0.7 1.4 33.0 11.6 0.4 2.1 18.0 11.2 14.1 18.9 12.9 1.3 2.7 0.1 0.2 0.0 0.9 0.1 16.0 12.8 0.3 0.3 0.0 0.6 21.5 4.1 2.7 2.2 1.6 17.7 24.2 0.7 6.2 1.5 14.3 6.0 17.6 2.0 0.0 7.7 0.0 5.5 10.1 2.7 0.0 5.8 0.6 23.9 1.2 17.6 0.0 9.5 0.0 1.8 13.5 0.0 0.0 10.1 6.9 0.0 0.2 2.6 13.7 14.2 9.2 1.8 9.6 28.0 4.9 7.8 0.4 0.5 3.2 15.6 0.6 1.9 0.3 4.8 8.1 0.3 2.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.0 1.3 0.9 0.2 0.1 0.0 0.2 2.7 0.1 0.1 1.3 1.1 0.3 0.9 0.7 0.6 0.8 0.2 1.2 0.4 C2CD5 "CDP138, KIAA0528" ENSG00000111731 "C2 calcium dependent domain containing 5" Q86YS7 12 22448583-22544546 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046194 Approved Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA046194: AB_10965327" "unprognostic (2.59e-1)" "unprognostic (1.84e-1)" "unprognostic (1.23e-2)" "unprognostic (1.17e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-3)" "unprognostic (1.17e-2)" "unprognostic (8.47e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-2)" "unprognostic (2.50e-2)" "unprognostic (1.51e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-3)" 10.2 11.2 18.9 16.3 26.6 11.8 13.6 48.5 30.7 13.1 18.5 10.0 10.0 17.8 15.6 12.3 10.4 15.8 15.4 8.8 14.6 16.5 15.7 7.8 11.2 13.8 13.5 22.8 17.4 12.3 23.3 26.2 9.3 26.9 10.3 20.0 13.3 12.7 10.0 8.0 11.7 14.8 12.7 10.8 15.0 19.2 12.9 12.9 18.7 15.5 4.9 14.3 11.7 11.8 7.3 6.1 15.3 14.1 12.8 8.0 4.3 8.6 8.6 19.2 10.4 12.7 16.9 12.2 9.6 10.4 18.0 21.5 9.4 11.6 9.9 4.3 9.0 7.8 12.2 7.9 25.2 15.9 12.7 12.2 9.4 8.4 11.7 16.4 14.7 9.6 5.7 11.5 20.3 13.0 7.9 6.4 11.6 9.3 15.4 25.2 38.1 6.5 13.5 21.2 13.3 10.6 7.1 8.9 7.7 8.7 8.5 9.1 11.3 11.0 11.2 10.8 8.8 9.7 10.1 5.2 4.0 15.9 6.7 12.5 7.9 15.3 6.1 2.9 5.5 13.5 7.2 7.3 8.0 5.4 6.1 5.0 7.2 5.7 6.2 12.8 14.1 3.5 8.0 4.3 18.9 26.6 48.5 30.7 14.6 16.5 13.5 22.8 26.9 12.9 CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "Carcinoembryonic antigen related cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 58.7;liver: 46.1;lymphoid tissue: 46.5" "Group enriched" "Detected in some" 4 "CAPAN-2: 12.5;Hep G2: 35.4;RT4: 23.3;SK-MEL-30: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "eosinophil: 20.6;neutrophil: 12.7" "Lineage enriched" "Detected in many" 11 "granulocytes: 20.6" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" 180000000 "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favourable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" 5.3 5.0 0.4 30.2 0.7 15.8 5.3 0.5 0.5 7.7 58.7 0.9 2.5 11.8 3.5 1.5 35.6 1.7 4.3 3.8 0.5 0.5 24.0 46.1 5.4 8.6 1.8 0.0 2.5 1.0 0.0 3.7 16.8 1.0 8.8 35.6 1.7 20.7 5.4 0.9 1.7 54.9 3.0 1.5 5.5 3.6 1.3 0.7 1.2 2.3 18.5 46.5 7.8 12.7 1.9 0.1 20.6 1.8 0.0 1.5 0.3 0.1 2.3 0.1 0.1 0.0 0.0 6.0 0.0 0.1 0.4 0.2 0.9 12.5 0.7 5.0 0.0 0.3 0.0 3.4 0.1 0.0 0.2 0.1 0.1 35.4 0.7 0.0 5.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 0.0 0.4 0.1 0.0 0.1 0.7 0.7 0.0 0.5 0.2 23.3 0.1 0.0 0.0 0.0 26.2 0.1 0.0 0.8 0.1 0.2 0.1 0.1 0.7 0.0 1.3 0.0 0.1 0.1 0.4 0.0 20.6 0.0 0.9 0.2 1.9 0.5 0.2 0.1 0.3 0.4 0.1 12.7 0.0 1.8 0.0 1.5 0.3 0.4 0.7 0.5 0.5 0.5 0.5 1.8 0.0 1.0 0.7 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880254 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "adipose tissue: 129.9;breast: 63.7;intestine: 60.5" "Cell line enriched" "Detected in some" 4 "ASC diff: 192.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory B-cell: 2.2;plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA018837, HPA020553" Approved "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 129.9 1.1 0.1 5.3 0.1 0.0 63.7 0.1 0.1 0.4 44.3 0.1 0.9 13.5 0.5 0.6 0.1 0.2 5.3 2.3 0.1 0.0 0.6 2.6 0.1 2.7 0.1 0.1 0.1 1.4 0.0 0.1 0.1 0.1 0.4 0.8 0.1 2.9 0.8 1.7 2.4 60.5 0.8 0.1 0.1 0.8 0.4 0.1 0.1 0.4 1.9 0.2 2.4 1.1 2.2 1.8 0.1 0.5 0.2 0.2 0.2 0.0 0.0 0.0 0.0 192.5 43.4 0.1 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.5 0.0 2.2 0.1 0.0 0.5 0.6 0.0 0.2 0.0 0.2 0.4 1.8 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 13 "U-698: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol 22000 "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: " "unprognostic (6.27e-2)" "prognostic favourable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 30.3 26.4 48.9 26.9 48.9 46.8 33.0 33.8 69.3 31.7 31.8 28.0 26.8 34.4 29.7 45.4 66.3 26.3 28.5 30.0 42.4 37.9 31.7 32.3 28.6 30.0 42.0 39.0 27.7 30.5 33.0 25.2 37.5 34.6 23.9 30.4 28.5 29.4 22.8 67.7 49.8 34.0 27.3 38.3 23.8 28.7 12.8 27.3 25.8 35.2 42.9 35.5 31.7 36.3 34.4 39.5 49.5 33.6 33.0 33.2 38.4 14.3 7.6 10.5 10.1 6.7 5.6 11.4 6.5 6.6 9.7 8.2 8.5 10.9 12.9 10.8 5.2 11.6 8.5 14.4 7.2 22.3 11.9 18.5 10.7 6.4 4.5 14.9 23.9 4.4 8.9 10.0 12.8 9.1 14.1 27.2 6.5 31.1 14.6 12.1 21.1 9.3 14.3 8.7 16.1 12.7 12.6 15.8 10.0 9.2 19.4 10.0 26.5 21.9 9.6 7.2 13.4 8.6 16.7 15.3 22.2 419.6 10.0 17.3 9.5 28.7 30.7 49.5 32.2 33.6 28.9 34.4 27.0 33.2 39.5 31.8 22.3 32.9 29.0 33.0 31.9 30.2 29.8 38.4 48.9 48.9 33.8 69.3 42.4 37.9 42.0 39.0 34.6 27.3 FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35351552-35353862 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;brain: 4.1;ovary: 4.8;pancreas: 9.6" "Cell line enhanced" "Detected in some" "Daudi: 2.8;U-698: 5.4;WM-115: 2.0" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" 0.0 0.0 1.2 0.2 1.6 5.7 0.0 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.0 0.0 1.9 0.9 0.0 0.0 0.1 0.7 1.7 4.8 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 4.1 0.3 1.6 0.1 0.0 0.2 0.0 0.0 1.2 0.5 1.9 0.3 0.7 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.8 0.4 0.1 0.4 0.0 0.0 0.1 0.3 0.3 0.8 0.2 0.0 0.1 0.4 1.4 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.6 0.1 0.0 1.1 0.2 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 5.4 0.1 0.2 2.0 1.6 0.3 0.7 0.4 0.2 0.4 0.3 0.3 0.2 0.0 1.2 0.3 0.4 1.9 0.7 0.2 0.5 0.2 0.0 FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40469953-40666597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.9" "Cell line enhanced" "Detected in many" "ASC diff: 18.9;Daudi: 20.0;HSkMC: 25.2;U-698: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favourable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favourable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" 41.6 6.9 7.0 18.4 11.2 8.0 35.5 2.3 5.0 21.4 13.4 8.4 7.7 3.5 27.4 9.8 9.5 17.2 13.3 9.9 7.8 3.9 8.3 25.6 15.3 22.4 8.3 3.9 46.0 12.2 3.8 6.2 9.5 6.5 7.9 6.8 5.7 7.5 9.3 85.9 12.3 7.6 18.6 9.7 10.8 7.4 12.3 9.0 9.4 13.1 9.0 15.6 14.4 16.2 6.1 0.5 2.8 1.6 1.1 7.1 1.0 0.3 0.6 5.6 0.1 18.9 3.7 5.4 0.8 1.1 0.2 0.1 1.4 1.3 20.0 3.7 0.5 4.8 4.4 2.4 0.3 9.1 4.6 0.0 0.6 4.4 9.0 0.1 0.5 25.2 16.4 0.1 3.1 14.2 0.3 6.4 1.4 0.7 0.0 0.2 8.2 1.4 14.2 6.5 1.5 10.5 2.5 1.2 0.3 0.7 3.8 0.8 0.6 0.5 8.3 0.1 1.1 0.0 0.5 3.6 1.3 25.9 0.5 0.9 2.6 0.9 0.8 0.5 1.5 1.0 2.3 3.2 3.9 2.2 0.5 6.1 7.1 5.3 2.8 1.1 1.6 0.0 5.5 1.0 7.0 11.2 2.3 5.0 7.8 3.9 8.3 3.9 6.5 9.0 GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142873-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "pancreas: 202.8" "Group enriched" "Detected in some" 5 "EFO-21: 37.1;U-2 OS: 52.8" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "pons and medulla: 3.7" "Region enhanced" "Detected in single" "midbrain: 2.0" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" 77950 "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" 1.0 0.1 0.2 0.6 0.2 1.1 0.2 0.2 1.8 0.2 6.6 0.2 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.1 3.4 0.2 0.2 0.2 0.2 0.2 0.2 202.8 0.0 0.2 0.2 0.5 0.2 12.6 0.2 0.2 0.2 0.2 2.5 11.0 0.2 0.2 0.2 2.4 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.0 2.9 0.0 1.4 8.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.5 0.2 GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "pituitary gland: 108.9" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 108.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GHSR ENSG00000121853 "Growth hormone secretagogue receptor" Q92847 3 172445133-172448456 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.4;blood: 2.4;pituitary gland: 7.4" "Cell line enriched" "Detected in single" 4 "HMC-1: 1.7" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 25 "NK-cell: 2.4" "Lineage enriched" "Detected in single" 25 "NK-cells: 2.4" "Region enhanced" "Detected in some" "hypothalamus: 3.8" "Low region specificity" "Detected in all" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" 0.0 2.4 0.0 0.8 0.5 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 7.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048798-39087743 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 19.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;HAP1: 1.3;HMC-1: 1.5;NTERA-2: 3.2;SCLC-21H: 8.0;SH-SY5Y: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 16.1;hypothalamus: 4.8" "Low region specificity" "Detected in many" "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" 0.2 0.1 0.1 0.0 1.8 0.0 0.9 0.1 2.2 0.1 0.1 0.8 0.0 2.4 0.1 0.6 0.1 0.0 3.5 4.8 1.4 1.4 0.1 0.0 0.5 1.0 0.1 2.3 0.0 19.0 0.0 0.1 0.0 2.0 0.1 0.0 0.0 4.1 0.0 0.4 0.3 0.1 0.0 1.4 0.1 1.8 0.4 0.0 0.4 0.8 0.4 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.2 0.0 0.0 0.1 0.0 0.0 0.0 8.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.8 0.1 0.7 1.4 1.4 0.1 2.3 2.0 0.0 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42230186-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 15.3 19.8 31.0 16.8 38.0 14.4 12.0 31.4 62.2 15.9 16.8 24.3 11.4 28.6 16.9 18.0 17.3 16.7 11.8 21.3 31.3 23.6 17.5 13.1 14.2 15.0 21.8 26.3 20.0 19.3 16.1 14.2 14.7 31.7 15.8 16.1 15.5 18.1 20.3 41.0 25.1 27.0 18.5 18.0 14.5 14.7 19.1 17.7 16.6 15.8 11.9 15.8 15.8 15.5 1.6 2.2 4.0 1.9 1.7 2.0 1.0 23.6 42.0 24.1 22.3 14.4 12.9 10.2 16.7 15.9 22.1 20.0 15.7 15.1 17.1 17.2 13.1 10.9 19.8 19.4 15.5 13.8 31.8 17.8 13.5 15.5 19.0 20.2 21.8 12.6 20.6 18.1 20.7 20.0 29.9 25.6 18.9 28.7 26.2 17.9 17.8 17.4 23.9 14.0 13.2 20.4 24.8 28.1 28.4 22.9 30.0 15.2 17.3 26.8 17.7 22.8 17.1 13.2 29.5 26.2 30.0 13.4 26.5 20.4 25.0 2.5 1.5 1.6 2.0 1.9 1.4 1.2 1.2 1.3 1.4 1.6 0.7 1.5 4.0 1.7 1.1 2.2 1.0 1.0 31.0 38.0 31.4 62.2 31.3 23.6 21.8 26.3 31.7 17.7 IGF2 ENSG00000284779 "Insulin like growth factor 2" 11 2129112-2158658 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "liver: 24.1" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;RH-30: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGF2BP2 IMP-2 ENSG00000073792 "Insulin like growth factor 2 mRNA binding protein 2" Q9Y6M1 3 185643739-185825056 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 43.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "myeloid DC: 5.5" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB017126, HPA035145" Enhanced Enhanced Cytosol Cytosol "CAB017126: , HPA035145: " "unprognostic (7.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.32e-1)" "prognostic unfavourable (5.12e-5)" "unprognostic (2.46e-3)" "unprognostic (8.25e-3)" "unprognostic (4.17e-1)" "unprognostic (3.45e-2)" "prognostic unfavourable (7.37e-5)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (9.45e-2)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.94e-3)" 7.9 8.9 1.0 6.4 1.9 7.6 4.9 8.6 1.6 6.5 16.4 1.6 1.5 11.3 7.6 4.8 3.7 8.3 8.1 9.9 1.7 1.4 8.0 2.6 14.0 4.0 2.8 0.7 6.7 11.3 7.6 2.9 43.0 4.5 4.9 11.6 16.9 9.0 1.6 3.2 4.3 21.4 3.3 3.7 5.8 9.9 5.1 1.5 2.4 8.6 3.2 3.3 6.2 12.5 0.0 5.5 0.9 3.3 1.3 0.0 1.2 28.2 2.4 27.6 5.2 15.1 23.9 16.9 14.9 21.1 23.2 27.9 20.3 8.0 0.0 22.2 12.6 12.9 12.9 21.7 37.7 0.0 13.4 8.0 0.1 14.0 32.3 0.2 0.0 17.5 11.5 15.4 60.0 21.3 7.8 0.0 17.0 0.2 0.0 6.8 20.2 10.2 2.9 11.0 8.4 15.0 0.1 1.7 0.2 1.1 0.0 26.6 2.2 18.9 32.3 8.1 17.6 10.1 17.1 0.1 0.0 0.0 8.0 0.0 11.3 0.9 3.0 0.5 0.0 2.8 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.2 1.3 3.3 1.0 0.0 1.2 1.0 1.9 8.6 1.6 1.7 1.4 2.8 0.7 4.5 1.5 IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38408994-38424447 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 11.0;pituitary gland: 7.4;thyroid gland: 27.2" "Group enriched" "Detected in some" 6 "AF22: 68.0;NTERA-2: 18.7;RH-30: 19.5;SCLC-21H: 70.0;SH-SY5Y: 67.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 12.5;olfactory region: 16.2" "Low region specificity" "Detected in many" HPA051354 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.59e-2)" "unprognostic (6.67e-2)" 1.6 2.6 3.8 1.1 11.0 0.3 0.4 4.7 4.7 0.7 1.0 1.0 0.0 1.9 2.1 0.5 0.7 1.0 1.9 3.7 3.3 2.3 0.7 0.6 1.2 0.4 1.4 1.5 0.5 1.6 0.4 7.4 1.1 1.8 1.6 0.7 0.2 0.5 2.9 0.3 0.3 1.2 2.1 0.6 0.4 2.5 3.3 1.5 2.6 27.2 0.0 0.4 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 68.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.1 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 18.7 0.1 0.0 19.5 0.1 0.0 0.0 70.0 67.9 1.1 0.0 0.0 0.3 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 11.0 4.7 4.7 3.3 2.3 1.4 1.5 1.8 1.5 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494571-1516888 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 114.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (7.47e-2)" "prognostic favourable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favourable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favourable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 27.9 10.5 12.7 13.8 13.5 25.9 37.0 14.9 17.7 13.4 13.4 14.9 9.8 9.1 12.8 12.2 12.0 10.4 12.9 17.5 12.8 12.6 11.6 10.5 20.8 14.3 12.8 12.0 14.3 18.9 12.0 10.8 15.9 21.2 13.5 11.4 114.9 12.9 12.2 26.4 22.3 13.9 10.9 10.7 16.2 12.8 20.8 11.3 22.1 27.3 13.8 16.4 12.5 14.1 12.1 16.5 36.4 27.0 17.0 30.8 24.6 9.4 13.1 5.4 10.3 14.0 7.8 8.0 7.9 13.4 9.0 11.5 8.1 5.6 8.4 15.2 12.1 12.4 12.8 5.1 9.3 21.8 21.6 5.2 10.0 3.2 17.7 4.9 10.2 9.2 13.7 9.0 8.9 14.3 5.7 15.2 5.9 6.7 14.9 4.0 2.3 8.9 11.5 4.2 8.0 7.3 5.8 4.2 10.8 6.2 12.2 14.1 10.3 4.0 10.1 7.9 8.1 11.4 10.2 8.0 13.4 4.5 8.9 5.1 9.9 36.4 19.9 31.9 22.2 18.7 18.2 12.1 20.7 22.4 16.5 11.3 17.7 18.9 33.3 17.0 27.0 11.9 30.8 24.6 12.7 13.5 14.9 17.7 12.8 12.6 12.8 12.0 21.2 11.3 INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 81.4;liver: 143.2" "Cell line enhanced" "Detected in many" "Karpas-707: 152.5;RPMI-8226: 71.5" "Cancer enhanced" "Detected in all" "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 45.7;non-classical monocyte: 81.4" "Lineage enriched" "Detected in all" 6 "monocytes: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Approved Vesicles Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavourable (9.62e-4)" "unprognostic (4.97e-2)" 18.4 9.2 8.5 8.3 8.8 9.7 14.1 10.1 14.3 6.0 7.4 21.8 7.5 12.5 5.2 8.3 15.6 4.6 8.0 5.6 10.8 11.6 6.4 143.2 18.5 6.9 8.6 8.3 16.4 27.2 4.6 5.2 17.5 23.9 15.9 6.7 11.9 31.4 3.1 2.4 10.5 14.2 5.1 19.2 4.5 13.4 8.2 8.3 10.7 3.3 6.1 6.9 11.2 5.6 10.0 13.6 10.7 81.4 4.0 12.7 12.5 18.9 3.5 9.4 5.9 25.0 33.4 5.2 1.5 21.6 4.5 30.1 2.1 27.5 12.4 4.4 11.7 10.3 6.4 11.2 5.4 3.8 18.9 3.3 6.5 0.0 12.3 5.7 56.0 20.8 6.2 34.9 3.2 6.0 6.2 152.5 5.8 9.8 28.0 15.1 9.8 2.2 5.2 0.0 71.5 35.7 9.4 7.0 5.6 5.0 3.6 7.9 3.5 19.3 6.8 5.0 1.5 9.5 3.9 37.2 6.5 11.0 22.2 22.5 4.6 3.1 4.9 2.1 8.7 45.7 4.4 7.7 6.0 7.4 13.6 10.0 5.9 6.7 10.7 4.0 81.4 7.7 12.7 12.5 8.5 8.8 10.1 14.3 10.8 11.6 8.6 8.3 23.9 8.3 KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043989-5046788 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 33.0" "Cell line enriched" "Detected in single" 21 "NTERA-2: 9.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 134 "plasmacytoid DC: 13.3" "Lineage enriched" "Detected in single" 134 "dendritic cells: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021516, CAB022562" Approved "CAB022562: , HPA021516: " "unprognostic (3.87e-1)" "unprognostic (9.91e-3)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (7.06e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (5.08e-3)" "unprognostic (6.73e-4)" "unprognostic (1.92e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (3.08e-2)" 3.4 1.4 1.9 0.9 8.6 0.7 1.2 0.4 2.3 1.6 3.3 7.2 0.0 1.1 1.7 2.6 7.6 2.1 2.3 33.0 3.5 5.8 1.9 0.8 2.3 0.9 2.3 2.2 3.2 2.4 0.6 7.5 3.4 8.8 3.7 1.3 7.2 0.9 2.0 5.3 0.6 1.1 3.0 3.9 1.2 3.3 0.8 4.9 0.0 1.1 3.4 1.2 4.5 3.4 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 1.9 8.6 0.4 2.3 3.5 5.8 2.3 2.2 8.8 4.9 KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;retina: 22.4" "Cell line enhanced" "Detected in some" "ASC diff: 3.5;CACO-2: 5.0;hTCEpi: 3.1;U-2 OS: 4.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001979, HPA042434" Enhanced "CAB001979: , HPA042434: " "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" 16.9 3.6 11.4 1.3 14.6 0.8 2.4 8.1 25.9 2.3 5.1 1.8 0.7 1.2 6.8 2.3 3.9 9.0 1.9 1.9 6.6 5.3 1.3 3.5 1.2 0.8 3.3 12.5 1.2 1.2 0.9 2.5 1.0 2.5 4.8 1.9 22.4 1.7 6.5 6.2 1.1 1.8 9.6 1.2 1.2 3.9 1.5 2.4 0.0 1.0 0.1 0.8 4.0 0.9 0.4 0.3 1.2 0.2 0.3 0.7 0.0 0.0 0.1 0.8 0.0 3.5 0.3 0.1 0.0 0.4 0.4 0.0 5.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 2.5 0.0 0.6 3.1 0.0 0.1 0.0 0.0 1.9 1.1 0.3 0.0 2.3 0.1 0.9 0.0 0.9 0.0 0.0 0.0 2.3 1.8 1.6 2.3 0.0 1.6 0.0 0.0 2.2 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.7 0.2 1.2 0.3 0.1 0.3 0.1 0.0 11.4 14.6 8.1 25.9 6.6 5.3 3.3 12.5 2.5 2.4 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69675802-69797111 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019547 Uncertain "HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favourable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 21.3 44.1 34.1 14.2 32.5 5.4 29.1 32.9 34.1 23.7 20.9 38.1 20.0 23.1 18.4 32.1 20.6 25.5 23.9 19.8 35.8 32.7 53.1 38.9 24.7 21.9 37.9 22.8 29.0 36.8 58.9 23.6 25.0 32.5 19.0 21.8 26.5 22.4 24.6 17.9 18.6 30.2 17.2 57.8 19.9 19.9 11.9 30.6 17.8 41.8 13.2 18.7 22.7 19.4 24.4 9.9 37.8 18.5 7.8 14.4 11.5 6.7 3.2 7.5 10.2 22.8 24.4 11.3 5.4 19.7 4.4 9.4 5.3 13.9 8.9 15.3 14.1 10.7 8.3 8.0 8.1 17.5 10.7 8.7 6.3 7.6 13.9 5.2 11.7 17.2 16.9 5.2 7.3 8.0 15.8 13.5 14.3 4.6 3.6 5.6 3.8 3.4 4.1 18.6 25.2 30.8 11.1 4.9 8.1 6.8 9.2 9.9 9.8 18.9 12.1 6.3 3.9 5.9 5.3 8.1 7.0 3.4 7.8 8.5 11.9 25.2 10.6 19.0 8.4 13.2 8.6 24.4 11.2 9.5 9.9 21.7 12.8 9.0 37.8 7.8 18.5 9.6 14.4 11.5 34.1 32.5 32.9 34.1 35.8 32.7 37.9 22.8 32.5 30.6 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568112 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 419.5" "Cell line enriched" "Detected in some" 10 "ASC diff: 21.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA006277, HPA006507, CAB017027" Approved 380000 "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favourable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 10.0 0.1 0.4 2.2 0.4 0.0 11.1 0.2 0.6 0.1 52.0 0.2 0.1 19.2 0.1 0.7 0.2 0.1 5.6 0.4 0.3 0.2 72.0 419.5 0.2 0.3 0.2 0.2 0.4 0.2 0.0 5.0 0.1 0.5 0.2 14.0 0.2 0.2 0.1 0.3 0.1 58.5 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.4 0.4 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.5 0.2 PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153118-18170540 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA069291 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA069291: " "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" 6.4 20.9 27.5 7.2 30.1 10.1 7.2 14.4 36.6 14.5 13.5 11.4 6.7 21.7 13.9 12.0 19.0 17.8 17.2 12.5 33.2 11.5 10.3 10.3 8.4 6.3 10.1 18.1 20.2 13.0 24.3 16.7 10.2 7.9 11.6 10.1 11.4 14.5 11.9 10.9 26.2 16.5 11.1 7.4 7.1 15.9 9.8 11.0 11.3 9.0 9.4 10.4 13.9 11.6 2.5 1.9 3.1 1.8 1.9 3.2 0.8 18.8 9.7 13.3 17.7 17.7 17.9 20.1 15.1 19.0 11.4 8.4 9.9 9.2 14.9 23.9 21.0 14.2 8.0 16.5 6.3 12.2 29.1 5.7 13.1 23.6 14.2 12.9 7.0 22.3 16.3 7.6 11.7 2.8 16.2 5.4 14.0 29.4 8.8 11.0 15.5 21.7 9.3 18.5 11.4 16.3 14.0 29.9 33.9 14.3 13.8 13.1 8.8 7.1 5.7 20.3 10.5 25.1 13.4 10.2 13.0 6.7 16.2 18.9 12.8 0.7 1.7 3.1 3.2 1.8 2.0 2.5 1.7 1.5 1.9 2.3 1.6 1.8 1.0 1.9 1.0 1.4 0.3 0.8 27.5 30.1 14.4 36.6 33.2 11.5 10.1 18.1 7.9 11.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Cell line enhanced" "Detected in many" "REH: 19.1;TIME: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA044496, HPA054252" Enhanced Supported Approved Vesicles Vesicles "CAB001948: , HPA044496: , HPA054252: " "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favourable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favourable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.3 2.0 2.8 2.8 4.3 5.1 2.3 3.8 6.8 3.2 3.4 0.5 5.3 8.1 3.6 3.9 1.3 1.8 2.0 4.5 4.8 3.4 0.0 1.4 1.1 4.9 0.6 2.9 4.5 2.2 4.7 3.4 11.6 1.1 1.9 3.6 2.7 2.6 0.3 1.0 1.0 19.1 13.5 8.6 2.9 3.7 2.0 4.3 1.7 5.7 12.3 4.6 1.9 19.2 6.2 6.5 4.5 3.7 0.0 0.0 6.8 5.1 4.5 6.2 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 RFX6 "dJ955L16.1, MGC33442, RFXDC1" ENSG00000185002 "Regulatory factor X6" Q8HWS3 6 116877212-116932163 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 7.4;intestine: 9.2;pancreas: 8.3;stomach 1: 11.8" "Group enriched" "Detected in some" 7 "HEK 293: 5.2;U-266/70: 2.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA037696 Approved "HPA037696: " "unprognostic (2.92e-1)" "unprognostic (4.66e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "prognostic favourable (3.59e-4)" "unprognostic (2.59e-2)" "unprognostic (1.63e-1)" "unprognostic (1.25e-1)" 0.1 7.4 0.1 0.8 0.1 0.0 4.5 0.1 0.4 0.2 6.9 0.2 0.0 3.4 0.1 0.0 0.3 0.1 1.3 0.1 0.1 0.1 0.1 0.1 1.0 0.0 0.1 0.0 0.1 8.3 0.0 2.1 1.5 0.0 0.5 2.0 0.0 1.2 4.0 0.1 0.1 9.2 0.0 0.1 0.1 11.8 0.9 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.0 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: " "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.6 10.4 8.9 8.4 6.1 9.0 6.7 9.9 9.2 8.7 9.7 8.5 5.3 12.9 12.3 8.2 5.5 11.7 8.9 14.0 7.1 13.1 8.8 6.8 9.7 9.1 13.6 8.9 9.1 6.8 10.1 7.5 11.3 11.7 8.3 6.4 74.4 16.1 5.8 6.0 8.0 9.5 15.0 12.1 7.2 7.9 6.5 7.8 8.3 4.8 5.2 9.5 7.5 9.7 8.5 14.1 6.9 13.1 15.0 12.7 14.5 6.4 8.4 6.7 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 SESN3 "MGC29667, SEST3" ENSG00000149212 "Sestrin 3" P58005 11 95165513-95232541 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 14.6;ASC diff: 24.8;ASC TERT1: 27.1;HSkMC: 14.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037935 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA037935: AB_10670534" "unprognostic (2.72e-2)" "unprognostic (3.06e-1)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (5.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.18e-1)" "unprognostic (8.19e-3)" "unprognostic (1.38e-1)" "unprognostic (3.78e-1)" "unprognostic (2.34e-3)" "unprognostic (4.43e-2)" "unprognostic (1.67e-3)" "unprognostic (1.69e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-2)" "unprognostic (9.42e-2)" 7.3 14.2 22.3 10.4 38.6 11.9 11.6 10.2 20.8 10.3 6.8 11.1 3.3 5.2 9.3 11.7 7.6 7.0 9.9 5.1 15.9 12.9 8.7 6.0 7.2 17.3 12.6 12.0 18.4 3.3 27.7 10.7 6.6 13.9 8.5 5.4 19.7 9.1 4.8 5.4 8.4 10.6 7.6 11.6 12.7 3.9 41.6 14.1 11.3 17.3 4.0 18.3 10.0 7.7 4.2 1.1 1.0 3.5 0.8 4.5 0.8 0.0 0.5 14.6 0.0 24.8 27.1 0.0 0.1 0.0 0.0 0.0 0.6 0.4 3.8 1.7 0.0 2.9 8.8 6.3 0.0 3.1 4.6 1.9 7.7 0.5 0.5 1.6 0.3 14.9 11.1 0.0 3.3 0.5 0.2 0.7 1.2 0.1 1.2 4.5 5.9 0.6 2.8 0.9 0.3 3.3 9.6 1.9 4.1 0.1 0.1 0.8 0.0 5.5 0.1 1.7 3.8 0.3 0.5 0.1 0.0 0.5 0.7 2.0 3.5 1.0 0.8 0.6 0.7 1.7 0.8 4.2 2.3 1.3 0.7 2.7 4.5 1.7 0.8 0.8 3.5 1.1 4.0 0.8 22.3 38.6 10.2 20.8 15.9 12.9 12.6 12.0 13.9 14.1 SNX19 "CHET8, KIAA0254" ENSG00000120451 "Sorting nexin 19" Q92543 11 130875436-130916509 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013447 Uncertain Supported Mitochondria Mitochondria "HPA013447: AB_1857347" "unprognostic (8.79e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (9.19e-2)" "unprognostic (3.43e-2)" "unprognostic (4.05e-2)" "unprognostic (2.89e-1)" "unprognostic (4.97e-2)" "prognostic favourable (3.56e-5)" "unprognostic (1.05e-1)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" 22.3 23.1 24.0 16.9 30.6 10.0 17.2 18.0 38.0 17.1 23.8 35.6 25.3 17.1 22.9 32.5 17.9 19.8 20.4 22.6 22.8 22.2 24.1 25.6 17.5 15.3 31.0 15.3 20.6 26.6 32.9 28.5 18.5 28.0 21.7 22.2 23.7 23.1 27.2 26.4 19.0 17.8 26.0 30.8 18.5 22.3 36.2 28.2 24.6 31.1 12.1 18.1 23.0 16.4 5.9 5.4 11.3 6.6 3.6 6.2 5.2 6.7 7.4 9.6 13.4 28.9 20.4 6.3 18.0 21.4 9.1 9.5 8.4 13.0 6.4 12.6 19.8 12.3 1.4 12.9 11.7 10.3 5.8 11.6 7.4 0.0 21.0 0.0 9.1 23.2 16.0 9.3 10.2 11.1 10.2 0.0 19.4 4.9 9.4 7.7 2.9 9.5 7.2 9.1 3.7 9.9 12.2 9.4 8.7 7.7 12.4 6.1 22.0 7.3 14.7 12.8 9.5 10.4 10.5 2.2 0.0 0.0 5.3 7.7 14.6 11.3 6.0 4.4 4.8 6.4 6.2 5.9 4.7 5.7 5.3 4.4 5.6 4.4 3.6 3.6 6.6 5.4 4.1 5.2 24.0 30.6 18.0 38.0 22.8 22.2 31.0 15.3 28.0 28.2 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 35.5;HBEC3-KT: 33.0;PC-3: 32.1;RT4: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 5.3;non-classical monocyte: 4.4" "Group enriched" "Detected in many" 6 "dendritic cells: 3.0;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Plasma membrane,Cell Junctions,Cytosol" 20000000 "Plasma membrane, Cell Junctions" Cytosol "CAB004023: AB_2106059, HPA030875: " "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavourable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavourable (1.63e-4)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favourable (5.22e-5)" 6.9 17.5 12.8 11.1 12.0 5.4 9.9 6.4 16.0 16.0 16.4 3.5 15.1 29.5 20.3 9.7 16.2 14.2 42.1 5.8 11.3 6.6 13.4 2.9 10.4 7.0 3.3 9.9 15.8 19.1 6.6 11.3 6.3 5.1 19.9 13.1 13.1 7.5 22.5 3.4 7.7 28.1 27.2 3.6 12.2 29.8 27.3 4.8 4.0 6.6 10.5 10.4 26.4 20.0 0.3 3.0 0.1 5.3 0.6 0.1 1.6 7.6 35.5 8.1 7.3 3.1 4.9 17.0 7.1 6.1 8.6 5.5 13.3 6.9 0.2 4.4 12.8 14.0 4.9 33.0 3.4 0.0 4.4 1.9 1.2 20.7 7.4 0.1 3.0 5.3 11.2 5.6 7.5 7.8 0.2 0.0 1.4 5.2 1.8 0.2 3.8 32.1 8.3 2.1 0.2 3.6 34.0 7.6 27.5 8.0 11.3 8.8 10.1 2.8 11.5 10.4 7.0 3.8 6.3 0.1 0.2 0.1 7.3 0.0 7.7 0.0 2.6 0.0 0.0 5.3 0.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.1 0.6 4.4 3.0 0.1 1.6 12.8 12.0 6.4 16.0 11.3 6.6 3.3 9.9 5.1 4.8 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favourable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favourable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.1 30.3 25.0 37.2 19.4 20.1 28.0 27.9 34.0 41.3 33.1 19.8 18.3 18.3 21.5 38.2 19.7 17.7 26.0 18.0 41.8 7.2 13.9 18.1 21.3 21.5 22.6 36.3 28.8 21.9 20.7 13.8 30.8 12.1 20.4 26.4 113.2 28.4 28.9 6.5 21.7 26.8 23.2 12.5 19.1 37.7 28.7 23.9 23.3 30.5 17.5 39.9 33.7 24.6 27.7 13.3 39.4 28.0 22.2 10.7 15.8 23.3 19.1 33.3 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavourable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.5 2.4 14.9 0.0 11.0 12.6 7.9 13.3 12.2 8.6 7.6 0.1 9.7 0.0 0.0 16.8 0.3 8.2 5.3 11.4 5.9 6.4 0.3 0.0 0.0 5.7 0.1 2.6 6.5 0.0 10.7 9.7 17.6 0.0 0.1 3.9 0.0 5.0 1.1 6.3 3.7 2.7 9.1 0.1 2.9 0.8 19.1 25.3 0.1 0.0 23.8 0.0 8.0 13.8 15.3 11.8 0.1 11.0 1.3 0.4 2.8 11.2 1.2 12.8 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 CAPN10 ENSG00000142330 "Calpain 10" Q9HC96 2 240586716-240617705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004170, HPA056098" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA004170: AB_1078381, HPA056098: " "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (9.29e-3)" "unprognostic (6.09e-2)" "unprognostic (5.44e-3)" "prognostic favourable (8.47e-5)" "prognostic unfavourable (4.78e-6)" "unprognostic (7.48e-3)" "unprognostic (7.94e-2)" "unprognostic (1.31e-2)" "prognostic favourable (7.94e-5)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (1.19e-1)" "unprognostic (6.88e-2)" "unprognostic (5.76e-2)" "unprognostic (5.58e-3)" 9.2 11.8 16.8 12.9 15.1 10.9 6.6 20.5 15.7 8.3 13.6 12.8 10.0 20.8 11.3 8.0 9.7 9.8 10.2 11.5 15.9 10.7 14.2 9.3 8.4 15.3 11.2 18.1 10.0 13.0 8.6 13.2 7.3 11.1 10.6 12.2 12.4 14.6 10.7 6.5 19.5 16.2 8.3 8.1 21.0 15.0 10.7 13.7 15.1 9.3 5.6 13.2 8.3 7.0 1.5 2.0 7.7 1.8 5.8 2.2 0.8 5.1 7.8 7.7 6.0 3.0 2.5 13.4 6.6 2.8 4.4 4.3 5.7 12.4 3.9 2.3 2.3 8.8 1.9 4.4 2.3 14.9 13.6 7.2 12.9 10.0 4.9 4.6 10.2 2.2 3.1 4.6 1.9 3.3 8.0 4.9 1.8 4.5 10.3 17.7 11.5 5.5 9.8 5.4 8.3 6.9 6.2 19.4 15.2 4.2 6.0 8.3 3.0 5.7 5.7 7.6 6.5 6.1 7.9 12.2 2.7 7.0 7.2 8.5 7.1 1.7 1.8 3.3 2.0 1.0 0.5 1.5 1.3 2.0 0.8 1.5 1.2 1.8 7.7 5.8 1.1 2.0 2.2 0.8 16.8 15.1 20.5 15.7 15.9 10.7 11.2 18.1 11.1 13.7 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050486-87094866 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.4" "Cell line enhanced" "Detected in all" "Hep G2: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" 26000000 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favourable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavourable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favourable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 15.5 21.5 57.8 9.9 54.5 5.9 23.2 13.4 37.9 12.1 14.5 19.9 5.5 18.4 10.9 7.5 17.0 11.5 12.6 16.7 44.1 35.3 56.2 182.4 13.1 11.5 40.6 30.8 17.5 15.2 8.7 6.6 13.5 31.1 26.5 14.6 8.1 10.0 13.3 9.2 15.3 19.8 14.0 22.7 10.2 12.2 6.4 33.2 12.6 16.1 8.7 13.1 14.0 9.5 9.2 15.8 9.2 14.6 13.7 11.9 5.9 24.0 19.5 15.3 25.9 29.1 35.9 16.7 19.0 33.0 18.5 20.3 44.9 23.6 27.1 15.6 27.7 38.0 19.9 19.2 19.8 19.5 15.7 13.1 11.7 106.0 65.0 30.7 19.1 24.7 36.2 20.5 61.4 22.0 13.2 24.5 19.9 17.5 27.6 27.6 17.4 15.7 21.0 19.5 17.6 53.1 19.7 7.9 14.8 17.1 13.6 24.3 18.6 21.6 21.8 9.6 8.5 19.4 19.3 14.7 15.1 32.4 23.2 35.2 5.7 5.5 13.8 9.2 8.7 11.1 10.9 9.2 11.8 10.6 15.8 8.8 10.6 8.5 1.3 13.7 14.6 5.9 11.9 5.9 57.8 54.5 13.4 37.9 44.1 35.3 40.6 30.8 31.1 33.2 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035175 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Supported Supported Mitochondria 8700000 Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 36.6 19.5 8.5 15.6 9.2 6.1 41.7 5.4 9.7 15.2 29.7 10.6 9.4 23.3 18.3 13.3 20.5 15.7 12.4 98.3 7.8 8.1 37.2 60.3 10.6 8.8 10.0 7.0 17.1 17.8 9.8 6.8 5.1 9.2 15.6 25.0 11.6 20.4 12.5 64.6 9.0 37.1 19.6 10.2 8.0 19.1 12.6 7.2 40.9 16.1 38.0 13.1 14.2 10.6 18.6 22.6 5.6 10.7 20.2 13.0 8.9 8.8 8.3 18.0 13.1 43.3 13.9 8.7 13.0 19.4 14.2 14.0 5.9 16.7 50.4 7.0 10.7 11.9 23.9 18.1 15.7 15.4 12.5 11.7 15.9 13.2 6.9 24.7 5.5 14.5 9.7 10.0 9.2 9.5 14.5 26.8 16.0 16.1 41.9 9.9 8.5 11.1 32.0 25.2 25.2 15.3 36.1 21.7 12.5 12.6 45.1 12.8 21.5 19.6 5.3 10.0 5.7 14.1 7.1 15.2 17.6 21.9 13.6 16.8 7.7 0.0 6.1 5.6 10.1 7.8 12.5 18.6 11.4 12.1 19.7 15.5 13.0 13.0 0.7 20.2 10.7 22.6 10.0 8.9 8.5 9.2 5.4 9.7 7.8 8.1 10.0 7.0 9.2 7.2 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061841-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;prostate: 24.0;retina: 22.5" "Cell line enhanced" "Detected in many" "AN3-CA: 22.3;T-47d: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 13 "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 13 "B-cells: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011800 Uncertain "Secreted to extracellular matrix" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavourable (5.10e-4)" "unprognostic (2.11e-1)" 2.6 0.6 0.8 3.2 0.5 0.1 2.6 0.3 1.0 10.3 2.3 0.4 2.9 3.3 5.2 10.6 1.6 2.0 3.0 7.7 1.0 0.4 1.9 0.4 2.4 2.8 0.6 0.3 1.9 1.1 1.6 3.6 1.1 1.5 24.0 2.0 22.5 8.3 3.0 4.8 1.7 3.7 5.6 0.5 20.6 8.7 1.8 0.3 0.6 2.5 5.7 2.3 3.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.2 1.7 22.3 1.9 6.7 1.7 4.1 4.7 1.1 1.0 4.9 1.8 0.2 2.4 4.1 0.4 1.5 0.0 0.2 2.6 0.8 0.3 4.9 4.7 0.4 0.3 2.0 0.9 0.3 0.1 0.8 0.1 0.6 2.4 0.7 3.7 0.1 1.4 0.5 9.1 9.5 8.3 0.3 0.4 1.1 0.3 1.0 0.5 0.7 1.3 28.5 0.6 0.1 0.6 1.9 0.3 1.1 0.7 2.1 2.0 1.0 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.3 1.0 1.0 0.4 0.6 0.3 1.5 0.3 MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5;parathyroid gland: 47.6" "Cell line enhanced" "Detected in many" "Karpas-707: 58.9;RPMI-8226: 39.9" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavourable (4.22e-4)" 8.4 7.1 16.6 9.5 27.5 15.7 5.5 27.4 34.5 6.2 4.4 7.8 0.4 3.3 4.2 3.2 5.0 3.6 7.3 4.6 15.9 15.4 4.6 2.7 7.3 11.2 15.6 17.6 5.4 4.3 47.6 10.5 5.2 29.3 4.5 5.2 9.9 4.0 3.4 4.1 10.4 3.9 7.7 10.1 7.3 4.1 4.6 7.1 3.1 6.8 2.7 10.3 7.3 4.2 2.3 5.2 6.3 4.4 0.7 4.5 1.9 5.4 9.6 5.1 6.1 5.2 6.4 5.5 9.9 9.0 5.3 4.2 0.9 2.2 5.2 2.6 11.8 4.5 11.7 10.2 6.6 29.4 2.7 4.8 2.5 1.1 2.7 2.5 4.7 4.2 6.4 7.8 15.5 30.8 0.1 58.9 10.2 9.6 2.2 0.3 2.3 7.7 4.1 8.2 39.9 4.4 3.9 3.8 2.2 9.2 7.6 18.0 4.0 2.8 14.7 10.7 4.6 5.0 9.6 6.1 13.5 6.3 11.7 7.3 15.4 0.9 4.4 5.4 2.9 3.6 4.5 2.3 2.9 1.9 5.2 1.6 0.5 1.0 6.3 0.7 2.6 3.1 4.1 1.9 16.6 27.5 27.4 34.5 15.9 15.4 15.6 17.6 29.3 7.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;HDLM-2: 21.5;NB-4: 22.1;SCLC-21H: 12.2;SH-SY5Y: 12.4;THP-1: 10.8;U-87 MG: 15.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavourable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.3 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 0.0 0.4 0.0 0.0 21.5 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.3 22.1 3.0 0.7 0.0 0.7 0.1 0.0 0.0 12.2 12.4 0.0 0.0 0.0 0.0 10.8 3.2 5.0 1.9 0.0 0.3 0.1 0.0 0.0 15.1 9.0 3.6 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 SHC1 "p66, SHC, ShcA" ENSG00000160691 "SHC adaptor protein 1" P29353 1 154962298-154974395 "Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001844, CAB005374, CAB016305" Supported Enhanced Cytosol Cytosol "CAB005374: AB_632395, CAB016305: AB_628249, HPA001844: AB_1856826" "unprognostic (4.12e-2)" "prognostic unfavourable (6.74e-4)" "unprognostic (1.10e-2)" "unprognostic (3.77e-2)" "unprognostic (6.40e-2)" "unprognostic (4.08e-3)" "unprognostic (2.94e-3)" "prognostic unfavourable (1.92e-4)" "unprognostic (9.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (2.22e-16)" "unprognostic (7.19e-2)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (1.31e-1)" 45.1 36.4 14.6 27.8 15.9 20.4 43.6 11.8 12.6 33.9 30.5 11.1 32.9 23.1 34.8 28.1 31.4 32.5 30.5 23.4 11.7 8.5 30.1 54.7 37.5 36.5 13.9 8.7 36.1 21.5 23.0 44.7 47.3 18.9 31.9 23.7 31.5 22.4 24.9 22.1 20.3 39.5 35.4 16.0 38.6 25.8 16.2 11.1 19.9 37.7 21.1 29.8 40.4 31.2 13.9 21.8 31.9 27.0 12.7 23.7 19.8 13.9 29.0 22.3 35.9 24.5 49.2 11.7 51.1 46.6 29.7 22.6 10.3 33.8 7.5 41.9 61.4 12.0 5.9 50.6 26.8 9.2 3.2 19.3 23.9 18.2 64.1 6.2 22.0 73.0 60.1 37.0 46.2 65.1 8.5 60.9 62.1 11.5 7.1 3.8 19.5 12.3 6.4 7.4 15.5 14.3 10.6 2.8 77.8 30.6 17.1 16.7 25.0 13.1 77.1 47.0 29.4 9.9 26.7 27.5 17.6 12.8 45.8 8.4 60.7 17.0 20.8 31.9 23.7 27.0 23.5 13.9 19.0 20.9 21.8 13.3 15.6 14.1 17.0 12.7 25.7 10.0 14.1 19.8 14.6 15.9 11.8 12.6 11.7 8.5 13.9 8.7 18.9 11.1 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047465-2089487 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: " "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favourable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 13.9 11.9 16.9 12.4 20.0 10.9 13.2 35.1 26.9 20.5 17.0 19.4 17.9 14.0 20.1 12.2 13.0 18.6 15.0 14.0 13.3 8.8 11.8 9.8 12.7 10.1 13.8 14.7 21.1 16.1 20.0 18.1 10.6 14.6 13.8 10.8 16.7 22.9 19.6 31.7 14.5 13.2 13.5 11.4 12.9 16.6 21.4 12.9 14.1 20.1 11.3 10.9 18.0 14.0 4.7 5.6 7.7 4.9 3.6 7.0 3.7 7.2 11.6 16.1 18.2 19.2 16.2 13.6 17.4 11.9 13.1 11.2 13.9 13.8 10.9 15.5 14.3 12.0 9.6 12.6 9.8 8.3 15.8 10.3 22.5 5.7 13.2 12.8 12.5 19.1 8.0 10.6 7.9 12.3 10.0 9.8 11.6 14.4 15.2 3.8 16.7 11.4 24.2 17.6 13.9 5.3 6.5 12.2 23.1 24.8 16.4 8.8 15.0 9.5 19.4 13.8 9.4 12.3 8.8 21.9 21.8 21.8 5.7 5.2 16.3 6.2 4.9 5.4 7.0 4.7 6.7 4.4 4.4 4.1 5.6 4.7 3.1 4.8 7.7 3.6 3.7 1.5 3.2 3.7 16.9 20.0 35.1 26.9 13.3 8.8 13.8 14.7 14.6 12.9 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Group enriched" "Detected in some" 4 "ASC diff: 15.1;HDLM-2: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.1 15.1 0.4 0.3 0.4 0.4 0.1 0.5 2.2 0.2 0.0 0.2 1.2 0.0 0.1 0.0 0.3 6.6 1.0 0.0 0.0 0.5 0.0 0.0 1.1 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 1.3 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940823-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "prognostic favourable (5.27e-4)" "prognostic unfavourable (5.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (5.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.84e-1)" "unprognostic (8.63e-2)" 26.8 24.8 20.4 16.4 25.9 65.7 29.6 18.1 29.0 22.2 19.3 33.2 17.1 16.2 18.0 33.7 49.1 24.8 18.5 39.6 19.8 19.5 30.5 56.8 41.5 33.6 20.7 14.3 22.6 66.2 30.4 21.6 63.1 20.2 23.1 21.6 38.3 39.7 17.9 43.5 46.1 24.4 18.2 30.2 36.9 24.8 24.9 18.3 21.9 26.6 28.6 32.1 25.0 29.3 21.6 28.8 112.6 49.9 16.0 23.4 63.8 24.5 23.4 14.3 15.7 30.0 23.1 73.2 27.6 32.2 28.6 26.5 23.4 29.8 16.4 20.5 31.2 30.5 21.3 37.8 26.0 31.0 24.3 12.6 29.7 18.5 29.6 26.1 19.2 27.3 61.6 31.1 31.8 28.1 32.5 34.9 28.8 26.8 21.5 19.2 31.4 26.8 17.2 34.9 31.8 27.7 29.6 23.6 24.4 29.1 43.5 33.9 31.6 25.3 25.1 21.1 16.7 10.3 30.3 36.9 50.0 18.6 30.3 15.1 24.7 39.6 49.9 59.9 19.7 33.5 20.4 21.6 21.0 19.3 28.8 21.4 21.0 18.4 112.6 16.0 32.3 19.9 23.4 63.8 20.4 25.9 18.1 29.0 19.8 19.5 20.7 14.3 20.2 18.3 AL035425.2 ENSG00000260548 X 108722070-108732687 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "ovary: 13.0;pituitary gland: 7.4;thyroid gland: 8.9" "Cell line enhanced" "Detected in some" "HEK 293: 18.6;NTERA-2: 2.6;RT4: 4.8;WM-115: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 2.9 0.0 0.0 3.9 0.9 0.0 0.5 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.5 13.0 0.9 0.0 7.4 0.0 0.1 0.0 0.0 0.7 0.0 1.1 0.0 1.5 0.1 0.0 0.4 0.0 8.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL358075.4 ENSG00000278139 1 46043661-46176488 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 27 "testis: 43.2" "Group enriched" "Detected in some" 5 "HeLa: 4.5;RT4: 14.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA005751 Uncertain "HPA005751: AB_1855350" 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 43.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 1.4 0.0 1.8 0.5 0.0 0.0 0.5 0.0 0.2 0.0 0.0 2.0 0.4 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227737-57273468 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "naive B-cell: 20.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011138, HPA073477" Approved Uncertain "Mitotic spindle,Centrosome" 28000 "Mitotic spindle, Centrosome" "HPA011138: AB_1844959, HPA073477: " "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favourable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 18.3 14.0 20.9 15.3 17.9 13.7 22.5 25.2 23.7 18.5 15.7 12.8 16.8 12.6 19.2 14.5 21.0 16.0 13.2 23.7 15.8 15.4 17.0 14.3 15.3 24.3 15.4 18.8 24.0 38.2 28.4 20.4 14.1 18.8 15.7 14.4 11.0 18.0 22.2 40.5 19.9 14.5 20.5 16.7 15.0 16.3 10.5 15.7 20.9 20.0 15.2 18.9 17.7 20.8 20.7 12.0 2.5 3.9 4.7 3.5 1.7 14.6 6.4 6.3 22.8 10.8 15.2 13.2 7.8 4.8 7.9 9.0 7.4 8.8 23.8 3.2 12.0 2.9 16.7 13.4 13.5 17.9 7.5 13.4 10.2 7.8 11.7 29.8 9.9 11.2 12.3 10.0 10.9 12.5 4.5 15.0 8.8 5.0 23.5 7.3 9.8 11.0 0.8 25.5 12.7 13.8 8.3 6.3 13.5 10.7 16.0 10.2 7.8 19.4 11.8 13.0 9.2 18.9 15.0 13.8 20.2 16.7 14.1 14.4 8.4 1.6 3.9 2.5 2.6 3.0 3.5 11.3 2.8 2.4 7.2 20.7 2.6 1.9 1.0 4.7 2.5 12.0 1.1 1.7 20.9 17.9 25.2 23.7 15.8 15.4 15.4 18.8 18.8 15.7 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1, UBX domain containing tether for SLC2A4" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favourable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favourable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavourable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 10.3 12.6 14.3 12.6 14.5 16.8 10.6 16.5 20.8 9.9 12.9 16.7 11.8 17.5 10.1 15.8 11.9 9.3 15.1 11.5 13.1 12.6 15.8 31.9 14.1 14.8 18.9 12.9 8.8 17.8 17.0 19.7 21.8 14.8 13.2 7.1 14.4 22.6 9.9 25.1 15.5 14.4 9.1 12.6 13.2 13.0 16.9 14.6 9.8 16.4 12.9 13.0 9.7 8.3 8.1 14.6 15.7 11.3 7.2 10.5 5.2 4.9 8.8 3.4 5.0 2.2 2.7 14.9 4.7 3.6 5.7 5.6 5.1 5.8 5.1 4.9 3.4 2.4 3.7 3.6 1.8 3.5 11.2 5.7 7.2 80.8 7.1 5.0 8.3 3.1 3.9 2.9 2.0 5.5 5.7 7.3 3.2 17.0 4.6 10.9 4.3 6.4 5.1 5.0 10.4 5.6 4.6 9.2 9.4 3.9 12.3 8.8 7.4 12.0 4.5 9.9 6.8 7.2 5.9 5.3 3.2 5.7 5.3 5.1 5.9 15.7 11.3 8.0 6.7 7.6 4.0 7.9 10.5 9.0 14.6 8.1 8.0 6.0 2.9 7.2 9.3 9.1 4.9 5.2 14.3 14.5 16.5 20.8 13.1 12.6 18.9 12.9 14.8 14.6 BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: " "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" 23.1 23.2 35.3 12.6 30.7 17.7 20.6 15.9 43.9 21.2 25.7 22.7 20.1 24.0 18.3 19.7 18.8 23.2 22.5 30.3 32.7 23.8 21.4 22.3 17.7 14.3 29.6 20.2 18.8 26.9 19.4 15.2 24.9 18.4 22.9 13.6 23.1 39.9 27.0 23.9 20.4 21.1 17.2 22.9 14.9 37.8 18.6 14.8 19.3 29.2 15.8 14.1 18.2 14.4 26.5 42.0 43.5 32.3 24.0 30.7 23.1 31.9 30.1 8.8 13.2 10.7 13.1 12.9 13.6 15.9 21.0 16.7 18.3 18.4 6.9 24.5 12.7 17.0 5.7 21.4 4.2 26.7 21.0 8.5 27.2 8.7 16.5 7.4 16.0 12.6 18.5 16.1 9.9 13.2 3.2 14.9 9.1 31.8 16.5 16.7 3.4 38.5 15.7 5.2 19.3 12.7 15.1 18.2 24.4 13.7 16.3 16.6 24.5 11.1 10.9 25.7 17.4 39.8 14.9 28.3 21.0 7.0 21.0 5.3 14.0 32.5 32.3 43.5 25.3 24.0 25.8 26.0 26.9 24.6 22.5 26.5 19.4 20.0 41.7 24.0 22.6 42.0 30.7 23.1 35.3 30.7 15.9 43.9 32.7 23.8 29.6 20.2 18.4 14.8 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564604 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "blood: 47.8;intestine: 23.5;lymphoid tissue: 39.8" "Cell line enhanced" "Detected in some" "Daudi: 43.0;REH: 11.6;RPMI-8226: 14.2;U-698: 21.0;U-87 MG: 8.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 47.8;naive B-cell: 33.9" "Lineage enriched" "Detected in many" 5 "B-cells: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005093, HPA069571" Approved Approved Nucleoplasm Nucleoplasm "CAB005093: AB_2274756, HPA069571: " "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.2 0.1 32.3 0.1 1.7 0.2 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.0 1.9 0.2 0.4 0.3 0.1 0.1 1.3 0.5 0.6 27.6 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.3 2.4 0.0 0.1 0.1 23.5 0.0 0.1 31.9 1.4 0.2 0.0 3.9 0.7 0.4 39.8 2.5 0.4 47.8 4.3 0.1 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.6 0.0 14.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 3.7 21.0 8.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 9.8 47.8 0.3 1.1 0.0 33.9 0.2 0.1 0.1 0.0 0.0 4.3 0.4 1.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.0;skin 1: 7.8" "Group enriched" "Detected in some" 5 "EFO-21: 8.1;U-2 OS: 8.1" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "neutrophil: 2.6;NK-cell: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" 38190000 Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.0 0.0 0.5 0.2 0.0 0.0 0.5 0.2 0.2 0.1 3.4 11.0 0.1 0.0 1.2 0.2 0.1 0.2 0.0 1.0 3.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 1.2 0.4 0.0 0.1 7.8 10.4 0.1 0.2 0.0 0.3 2.4 0.2 0.1 0.0 0.4 0.3 0.6 2.6 0.3 2.2 0.4 0.2 0.3 0.0 0.0 0.6 0.4 0.1 1.5 1.1 0.0 0.1 0.0 0.6 0.4 0.1 8.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 0.3 0.1 0.1 0.1 0.3 0.0 0.3 0.0 0.0 0.5 0.3 0.1 0.8 0.1 0.3 0.0 1.3 0.0 0.0 1.2 0.3 0.0 0.0 0.7 0.6 0.1 0.0 0.0 8.1 0.1 0.0 1.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.2 0.0 0.6 0.3 0.4 0.0 2.6 2.2 0.3 0.0 0.0 0.2 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.1" "Cell line enhanced" "Detected in all" "HMC-1: 29.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011044 Approved Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" "Nucleoplasm, Nucleoli" "Nuclear membrane, Cytosol" "HPA011044: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favourable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavourable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 5.2 7.0 15.9 7.3 33.1 14.7 4.8 18.2 31.2 5.8 10.3 7.5 8.3 18.7 4.1 6.1 9.4 10.9 6.3 7.9 15.8 13.6 6.3 7.3 8.3 8.5 9.1 12.6 3.9 7.5 7.8 14.2 4.8 11.7 4.8 8.8 5.6 8.7 7.0 8.3 12.5 19.4 6.1 7.3 9.2 5.5 2.6 9.1 7.0 5.5 6.7 6.6 6.6 5.3 0.4 1.1 5.7 4.2 1.7 1.6 1.1 3.3 2.5 3.5 7.1 4.5 1.9 2.2 5.1 4.5 5.1 4.3 4.0 3.5 5.1 13.4 3.5 7.6 4.3 2.2 2.0 8.0 3.6 20.0 3.2 2.9 6.0 5.7 29.2 2.2 4.5 9.5 3.5 3.2 8.3 9.1 4.7 8.9 6.4 13.8 1.3 6.8 4.1 3.1 5.8 5.0 2.1 10.7 6.1 2.1 11.5 3.2 20.2 7.7 3.8 4.7 1.6 5.6 8.9 4.0 2.4 2.0 2.9 9.9 5.2 1.1 3.0 5.7 0.6 3.2 1.0 0.4 1.4 1.4 1.1 0.1 1.6 0.8 1.0 1.7 4.2 0.7 1.6 1.1 15.9 33.1 18.2 31.2 15.8 13.6 9.1 12.6 11.7 9.1 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 125.1;LHCN-M2: 138.1;RH-30: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: " "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.3 10.8 14.3 12.7 13.1 11.5 9.5 5.4 17.6 23.8 19.8 15.4 8.9 13.6 9.7 8.4 7.2 19.7 125.1 18.1 6.7 9.1 12.7 7.3 10.8 15.4 14.4 8.8 11.3 9.2 14.6 16.8 15.3 13.5 11.7 138.1 13.5 13.7 11.7 16.8 11.0 12.4 434.6 12.6 7.4 14.7 12.9 12.1 9.5 7.2 14.4 9.6 17.5 6.9 11.2 10.5 12.6 10.9 5.8 9.5 20.9 10.3 13.3 13.4 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15665031 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "kidney: 204.4" "Cell line enhanced" "Detected in many" "HaCaT: 10.7;hTERT-HME1: 6.1;RPTEC TERT1: 9.8" "Cancer enriched" "Detected in many" 35 "renal cancer: 106.2" "Region enriched" "Detected in single" 9 "pons and medulla: 5.0" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" "Endoplasmic reticulum, Vesicles" "HPA048543: " "unprognostic (1.27e-1)" "unprognostic (4.77e-2)" "unprognostic (2.45e-2)" "unprognostic (2.66e-2)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-2)" "prognostic favourable (5.65e-4)" "unprognostic (1.05e-2)" "unprognostic (3.03e-1)" "prognostic favourable (6.78e-9)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-2)" 0.1 0.2 0.3 0.1 0.4 0.0 0.3 0.1 0.2 0.2 0.2 0.5 0.1 0.1 0.2 1.6 0.2 0.4 0.6 0.2 0.5 0.4 204.4 11.5 0.6 0.1 0.3 0.1 0.8 1.2 4.0 0.2 0.7 5.0 0.3 0.0 11.3 0.3 0.1 0.1 0.2 0.2 0.1 0.2 0.1 2.4 0.3 0.1 0.2 0.7 0.1 0.1 0.4 0.2 0.9 0.6 0.0 0.5 0.0 3.0 0.4 3.0 2.2 1.5 0.6 0.8 1.2 1.0 0.1 0.0 0.1 0.1 0.2 0.5 0.3 2.1 0.1 10.7 0.9 2.5 0.0 0.4 1.4 0.3 0.0 1.0 1.6 0.0 0.0 0.2 2.4 0.4 6.1 0.0 0.7 0.6 0.3 3.5 0.2 0.4 3.6 3.1 0.3 0.5 1.3 9.8 0.2 1.4 1.3 0.8 0.2 2.0 1.0 0.3 0.1 0.2 0.5 0.4 0.0 0.6 0.3 0.4 0.9 0.1 0.1 0.0 0.5 0.0 0.6 0.2 1.3 0.4 0.8 0.5 0.6 0.9 3.0 0.9 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.4 0.1 0.2 0.5 0.4 0.3 0.1 5.0 0.1 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355926-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.2" "Cell line enhanced" "Detected in many" "BJ: 67.0;fHDF/TERT166: 66.1;TIME: 93.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" 120000 "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favourable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 42.4 6.0 9.1 8.7 11.0 1.1 44.6 6.1 9.0 13.8 13.1 6.4 10.2 5.7 14.9 9.8 12.4 14.2 17.3 32.2 8.6 8.7 28.6 6.2 24.7 13.2 7.6 10.2 15.5 9.2 18.0 4.3 116.2 12.0 14.9 9.4 24.7 13.1 13.8 25.9 13.7 9.0 23.1 10.8 17.5 10.2 8.1 6.2 3.0 18.1 7.9 4.5 16.9 22.3 0.8 5.5 3.4 1.4 1.1 1.6 0.2 14.0 10.7 2.2 2.5 10.4 11.8 18.3 67.0 35.5 37.6 19.8 13.5 4.9 0.0 43.7 66.1 6.1 1.6 10.8 30.8 0.1 1.2 0.4 14.4 7.8 33.5 0.3 0.1 16.5 8.1 15.0 27.1 52.6 0.6 0.1 39.5 1.2 0.0 0.1 1.7 3.2 0.7 2.8 2.1 23.7 5.8 0.2 0.0 11.7 3.8 0.4 10.5 0.2 93.2 47.6 17.1 5.9 32.4 3.7 0.0 0.1 14.0 0.0 14.5 3.4 0.4 1.2 1.6 0.2 1.2 0.6 0.7 0.9 0.3 0.8 0.2 1.0 0.5 1.1 1.4 5.5 0.5 0.2 9.1 11.0 6.1 9.0 8.6 8.7 7.6 10.2 12.0 6.2 EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030341-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 94.7;salivary gland: 109.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 53.5;eosinophil: 31.3;intermediate monocyte: 41.2;memory B-cell: 16.3;myeloid DC: 41.3;naive B-cell: 13.5;non-classical monocyte: 31.4;plasmacytoid DC: 31.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB005032: AB_562030, CAB005039: AB_562029, HPA023501: AB_1848095" "unprognostic (1.55e-2)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "prognostic unfavourable (8.86e-4)" "unprognostic (6.94e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-2)" "unprognostic (3.18e-3)" "unprognostic (7.21e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (4.57e-2)" "unprognostic (5.72e-3)" 17.7 3.4 2.5 4.9 3.6 9.2 21.7 1.8 3.2 5.5 15.4 2.0 7.7 6.2 5.3 2.1 22.2 5.0 7.0 9.4 2.2 1.8 6.0 39.6 6.9 7.4 4.3 1.4 9.3 94.7 1.7 2.2 8.7 2.8 7.4 4.6 2.8 109.8 8.0 38.4 4.9 9.0 7.1 4.2 9.3 10.6 3.0 2.7 2.7 3.7 12.6 9.2 11.3 11.1 16.3 41.3 31.3 53.5 4.0 7.6 28.0 20.4 10.6 3.1 18.4 4.0 3.5 13.6 22.7 10.6 12.3 19.7 7.0 5.3 8.0 15.9 11.3 10.9 10.3 18.5 7.3 6.1 33.5 46.8 4.7 9.6 41.8 15.1 7.5 9.8 30.2 13.6 25.5 19.7 25.5 21.4 5.1 12.8 13.2 36.8 22.9 42.7 11.6 13.0 28.2 4.6 2.0 43.2 32.8 4.6 7.5 53.4 10.0 17.8 18.5 7.4 24.3 21.9 17.2 30.8 16.7 9.2 17.3 26.8 16.0 5.1 53.5 31.3 3.9 41.2 3.5 16.3 4.5 4.0 41.3 13.5 3.6 3.6 4.7 4.0 31.4 31.3 7.6 28.0 2.5 3.6 1.8 3.2 2.2 1.8 4.3 1.4 2.8 2.7 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404379-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: , HPA061665: " "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favourable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 57.3 27.2 22.1 28.2 21.8 20.2 77.1 22.7 23.0 28.7 47.9 16.7 25.9 30.8 24.8 18.3 28.3 22.7 37.9 52.4 18.0 15.8 44.4 40.1 31.8 21.6 19.0 14.7 33.4 28.4 23.2 13.3 36.2 18.6 33.2 31.6 34.8 25.5 50.2 54.5 27.6 51.2 32.4 17.8 30.5 28.7 17.9 16.2 34.8 23.5 29.2 22.1 39.8 64.3 7.0 14.0 20.6 17.5 9.3 14.2 14.2 16.8 5.6 30.1 29.4 58.4 22.2 16.3 10.3 12.9 7.7 8.4 24.1 15.2 17.6 6.3 15.2 11.0 14.7 9.6 8.8 18.7 7.6 12.7 6.7 9.5 13.7 22.5 9.0 24.7 9.9 9.4 8.6 11.7 20.6 16.2 11.9 9.7 19.1 23.2 25.3 10.1 19.8 12.1 11.4 9.9 17.6 16.4 24.7 14.3 32.9 13.6 15.0 20.1 12.7 5.0 6.3 8.2 9.2 10.8 21.2 20.8 5.8 33.7 5.1 13.8 15.5 20.6 14.2 13.8 11.6 7.0 11.5 11.7 14.0 6.1 9.8 10.1 17.0 9.3 17.5 4.7 12.5 14.2 22.1 21.8 22.7 23.0 18.0 15.8 19.0 14.7 18.6 16.2 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747822-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favourable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 13.4 5.7 5.5 6.1 13.4 1.8 5.2 6.0 5.0 9.7 6.7 1.4 16.8 2.5 6.5 19.3 8.2 4.6 5.3 4.6 4.8 4.8 7.2 3.6 12.2 1.9 4.9 2.2 7.2 3.0 18.5 15.9 5.7 3.1 6.8 3.6 5.0 4.5 21.9 5.0 6.6 3.5 7.2 6.2 8.1 4.1 15.9 2.6 3.9 10.2 12.8 2.8 7.7 9.0 10.5 5.4 8.0 5.1 1.2 2.8 1.1 4.6 1.6 5.7 9.0 3.4 5.2 3.6 5.6 5.5 3.3 3.9 9.5 2.9 7.5 3.5 6.7 3.3 3.1 7.0 7.5 3.1 4.2 4.9 7.2 3.4 2.3 2.7 4.2 3.1 3.9 7.9 9.0 4.9 6.1 5.6 4.2 1.3 2.1 0.8 0.8 3.3 1.7 5.5 44.2 3.2 1.6 1.9 2.8 9.2 0.5 6.0 2.2 1.2 7.2 6.4 4.9 3.2 4.4 4.8 7.1 2.9 4.0 0.8 3.0 8.0 5.1 5.4 1.7 3.1 2.8 10.5 1.0 1.8 2.8 3.8 1.6 2.0 0.4 1.2 2.4 5.4 2.1 1.1 5.5 13.4 6.0 4.2 4.8 4.8 4.9 2.2 3.1 2.6 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FK506 binding protein 1B" P68106 2 24049701-24063681 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1;intestine: 24.9" "Cell line enhanced" "Detected in many" "Hep G2: 22.8;NTERA-2: 22.2;SH-SY5Y: 16.1;TIME: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles Vesicles "HPA045572: , HPA051798: " "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 2.9 5.9 25.0 2.8 30.7 1.9 5.9 15.7 23.1 5.1 7.2 1.6 7.4 24.9 3.6 4.2 4.5 4.5 7.1 3.4 31.1 14.0 4.4 4.6 9.0 2.2 13.0 19.7 4.6 4.9 6.4 2.8 5.6 7.9 5.1 4.6 2.4 3.3 9.2 1.1 3.6 6.7 4.0 5.2 1.8 13.3 1.6 4.4 0.6 5.0 1.1 3.2 7.1 3.5 1.5 2.2 4.4 0.8 0.3 5.4 1.1 0.1 1.0 8.9 0.0 5.6 2.2 3.1 3.0 3.1 1.3 1.9 0.6 1.0 0.0 2.2 5.2 3.4 13.1 10.2 0.8 1.5 8.4 3.0 0.1 22.8 2.1 0.0 7.3 2.1 2.4 3.0 0.6 8.3 0.7 0.0 2.9 0.1 0.9 0.0 22.2 1.5 1.5 0.7 0.0 1.0 0.6 2.2 16.1 0.1 0.0 2.8 0.6 1.1 19.4 0.0 2.8 0.1 0.7 0.5 0.2 0.0 3.2 0.0 0.7 1.3 0.8 4.4 0.3 0.7 0.0 0.3 0.6 0.5 2.2 1.5 0.0 0.2 0.1 0.3 0.0 0.4 5.4 1.1 25.0 30.7 15.7 23.1 31.1 14.0 13.0 19.7 7.9 4.4 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "pituitary gland: 149.9" "Cell line enhanced" "Detected in some" "CACO-2: 46.9;HEK 293: 21.9;K-562: 24.3;NB-4: 86.7;SH-SY5Y: 35.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "hypothalamus: 18.8" "Cell type enriched" "Detected in single" 15 "intermediate monocyte: 1.5" "Lineage enriched" "Detected in single" 15 "monocytes: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 111.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" 60030 "Golgi apparatus" Vesicles "CAB079779: , HPA049864: " "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavourable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 2.8 0.2 0.1 14.8 0.5 0.4 4.5 0.6 2.0 0.2 6.0 0.1 0.4 1.7 0.2 0.7 0.7 0.2 0.3 0.6 1.3 18.8 0.3 0.2 0.2 0.1 0.2 0.6 0.2 2.9 0.0 149.9 0.9 2.2 0.7 4.1 0.6 0.5 1.8 0.3 4.5 2.2 9.7 0.3 0.2 1.5 0.5 0.4 0.7 0.2 0.4 0.3 1.5 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 4.4 6.6 0.0 0.1 0.0 46.9 1.7 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 21.9 1.1 14.1 0.0 0.2 0.6 0.0 0.3 0.7 0.0 0.0 1.1 24.3 0.0 0.0 13.3 0.0 86.7 11.2 4.2 0.0 0.0 8.9 0.1 0.0 9.1 35.0 4.6 0.2 0.0 0.2 10.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.7 1.3 18.8 0.2 0.6 2.2 0.4 GIGYF1 "GYF1, PERQ1" ENSG00000146830 "GRB10 interacting GYF protein 1" O75420 7 100679507-100694037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020999, HPA023995" Enhanced Approved Vesicles,Microtubules Vesicles Microtubules "HPA020999: AB_2111744, HPA023995: AB_1855221" "unprognostic (3.82e-3)" "unprognostic (1.58e-1)" "unprognostic (2.56e-2)" "unprognostic (2.67e-2)" "unprognostic (7.46e-2)" "prognostic favourable (7.42e-4)" "prognostic unfavourable (2.30e-4)" "unprognostic (1.43e-2)" "unprognostic (8.06e-2)" "unprognostic (1.65e-2)" "prognostic favourable (1.35e-5)" "unprognostic (3.66e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (1.89e-1)" "unprognostic (2.79e-1)" "unprognostic (2.67e-3)" 15.5 17.3 22.1 15.9 23.0 28.2 16.3 66.8 32.4 20.6 14.0 18.9 27.3 17.1 25.1 20.2 11.5 18.3 16.4 13.2 20.3 9.4 14.4 13.3 13.5 18.5 14.1 16.3 29.8 23.8 17.8 26.3 16.2 15.7 17.1 9.3 19.6 26.5 25.7 25.5 31.7 17.6 12.9 9.3 24.0 17.0 18.9 20.4 11.8 20.5 10.4 14.2 14.3 14.0 4.1 3.9 8.8 2.6 2.5 5.1 0.9 6.9 7.2 11.6 17.0 5.6 4.4 20.7 6.6 5.4 4.1 4.8 4.2 12.1 9.8 8.6 4.8 8.4 5.7 6.7 2.6 10.4 11.6 6.8 17.8 6.0 5.5 7.7 11.7 6.9 5.4 5.3 7.6 4.1 18.7 9.7 3.7 15.8 13.6 42.7 14.2 8.8 21.9 6.1 9.8 3.0 6.4 10.5 16.5 8.6 13.9 7.6 6.3 13.0 6.4 12.1 15.0 19.7 6.0 7.9 3.5 5.3 7.0 15.5 7.1 3.3 2.6 2.2 5.1 2.3 3.8 2.7 3.4 3.2 1.0 4.1 3.1 3.2 8.8 2.5 2.5 3.9 1.8 0.9 22.1 23.0 66.8 32.4 20.3 9.4 14.1 16.3 15.7 20.4 GPR68 OGR1 ENSG00000119714 "G protein-coupled receptor 68" Q15743 14 91232532-91253925 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Amelogenesis imperfecta, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.0" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 7.1;U-87 MG: 26.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 16.4" "Group enriched" "Detected in many" 10 "NK-cells: 12.8;T-cells: 16.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (3.44e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "prognostic favourable (3.06e-5)" "unprognostic (3.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.10e-2)" "unprognostic (1.58e-1)" "unprognostic (6.84e-2)" "unprognostic (9.63e-2)" "unprognostic (9.42e-2)" "unprognostic (3.73e-1)" "unprognostic (8.31e-9)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (9.44e-2)" "unprognostic (2.78e-3)" 5.1 1.6 2.1 7.9 2.0 1.6 4.4 6.1 6.1 3.9 2.6 0.4 0.0 2.6 1.0 0.7 8.6 0.9 6.3 3.0 1.1 5.2 1.1 0.8 5.4 7.8 0.9 3.9 0.8 1.8 1.5 17.0 4.8 2.3 3.1 2.2 0.9 4.0 0.8 0.5 9.2 3.2 5.3 1.4 4.3 6.5 1.5 0.0 0.8 2.2 3.7 9.6 7.3 3.2 0.4 0.1 1.5 0.1 12.8 16.4 2.5 0.1 0.1 0.4 0.0 0.1 1.0 0.4 0.8 0.4 0.0 0.0 0.1 0.8 0.7 0.3 7.1 0.7 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.4 3.3 0.3 0.0 4.3 0.0 0.3 4.3 0.7 3.1 0.9 0.6 4.9 0.1 0.1 0.3 0.2 0.2 0.1 0.3 2.6 3.7 0.1 0.1 0.0 1.2 0.3 2.1 5.3 0.1 0.9 0.3 0.8 0.9 0.1 26.0 0.9 0.1 0.0 0.1 0.0 16.4 0.0 10.1 0.4 3.6 9.4 0.1 0.2 0.5 3.4 1.5 12.8 0.0 0.0 5.8 2.5 2.1 2.0 6.1 6.1 1.1 5.2 0.9 3.9 2.3 0.0 GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA030749, HPA030750" Approved Enhanced Nucleoplasm 1900000 Nucleoplasm "CAB002589: AB_10693935, HPA030749: AB_2673590, HPA030750: AB_2673591" "unprognostic (4.83e-3)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (6.04e-7)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-2)" "unprognostic (1.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" 29.0 29.2 36.1 48.2 40.3 56.3 23.6 42.2 41.6 18.5 27.8 28.2 19.1 29.2 28.3 19.4 27.0 22.1 22.5 32.2 34.7 33.9 24.9 32.2 33.7 54.8 30.9 29.2 21.8 16.7 21.8 21.8 33.1 26.9 21.4 27.9 21.8 21.2 25.6 27.8 18.6 30.5 30.6 42.6 56.7 22.8 10.8 27.1 45.8 20.4 15.6 53.1 29.8 19.2 24.7 25.0 64.9 42.8 12.0 13.4 20.7 24.8 21.7 14.9 18.0 16.5 15.5 34.0 26.3 21.4 27.7 26.6 18.6 16.7 32.5 15.6 24.0 14.9 21.5 18.9 28.8 16.0 19.7 34.8 14.3 27.1 14.9 40.0 68.0 14.3 19.8 28.9 14.5 33.2 23.5 22.6 20.1 31.0 46.8 38.7 10.3 22.1 28.1 32.0 23.5 21.1 18.6 18.0 26.0 22.2 21.7 27.7 24.0 64.7 21.1 26.6 20.2 21.0 26.7 41.5 31.9 52.2 20.5 31.3 19.0 25.1 32.1 38.5 13.4 38.4 11.7 23.7 12.1 13.2 25.0 24.7 12.7 12.0 64.9 12.0 42.8 16.7 13.2 20.7 36.1 40.3 42.2 41.6 34.7 33.9 30.9 29.2 26.9 27.1 HNF1A "HNF1, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 24.2;kidney: 17.2;liver: 15.6" "Group enriched" "Detected in some" 7 "A549: 6.2;CACO-2: 20.6;Hep G2: 22.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm Nucleoplasm "CAB010430: AB_2116746, HPA035231: " "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" 0.1 0.0 0.1 0.8 0.1 0.0 0.1 0.1 0.1 0.1 17.3 0.1 0.1 13.7 0.1 1.5 0.1 0.8 5.1 0.1 0.1 0.0 17.2 15.6 0.1 0.1 0.1 0.1 0.2 6.3 0.0 0.1 0.1 0.1 0.1 2.1 0.1 0.1 0.1 0.1 0.0 24.2 0.5 0.1 0.1 3.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.5 1.8 0.3 0.3 0.4 0.2 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.2 0.2 0.3 0.2 0.3 0.4 0.4 0.1 0.5 0.4 0.4 1.6 0.3 0.3 0.5 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836903 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.3;lymphoid tissue: 35.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 92.5;HBEC3-KT: 42.0;HMC-1: 34.3;hTEC/SVTERT24-B: 46.3;U-87 MG: 84.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "neutrophil: 34.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 34.4" "Low region specificity" "Detected in some" "Secreted to blood" 3370 "unprognostic (1.55e-3)" "prognostic unfavourable (1.31e-4)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.12e-2)" "unprognostic (2.63e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.72e-2)" "unprognostic (5.57e-2)" "prognostic unfavourable (7.49e-5)" "unprognostic (1.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.09e-2)" "unprognostic (4.01e-2)" 19.6 3.3 4.2 20.4 15.3 62.3 0.8 1.1 10.8 1.6 3.2 12.7 0.2 1.2 3.0 1.5 3.5 3.4 7.5 3.7 19.0 3.6 1.7 4.0 17.3 5.0 5.9 0.3 3.4 2.4 2.4 3.0 10.3 24.9 2.6 2.6 1.0 2.2 0.8 0.4 0.9 3.7 3.5 29.7 35.4 20.9 1.6 5.8 0.8 1.1 13.5 14.0 10.4 1.2 0.0 6.9 34.4 7.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 92.5 0.4 1.0 0.0 0.0 0.0 2.6 0.0 2.1 0.0 42.0 5.7 0.0 0.0 4.1 0.0 0.0 0.3 0.0 34.3 0.1 1.3 46.3 15.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 3.5 0.1 0.0 0.0 0.0 5.5 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 84.5 1.9 3.2 0.5 4.2 1.5 0.0 7.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 34.4 0.0 2.7 0.0 0.0 1.0 4.2 15.3 1.1 10.8 19.0 3.6 5.9 0.3 24.9 5.8 INHBB ENSG00000163083 "Inhibin beta B subunit" P09529 2 120346143-120351808 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.3" "Cell line enhanced" "Detected in some" "A549: 15.1;ASC diff: 21.0;MCF7: 18.2;PC-3: 29.6;SK-BR-3: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 14 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavourable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favourable (1.02e-4)" "unprognostic (1.76e-2)" 23.3 3.6 6.0 1.2 3.5 0.2 19.2 0.9 3.8 7.0 0.8 3.1 2.6 1.3 3.9 2.6 1.5 3.3 2.4 3.5 4.7 1.4 1.2 19.2 2.7 1.0 2.2 3.1 1.6 3.5 4.5 3.8 1.2 4.7 7.7 0.3 0.5 7.8 0.9 4.9 7.6 0.9 2.1 1.9 0.4 1.8 14.4 2.2 0.4 19.1 1.6 1.3 4.4 7.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 7.6 15.1 0.0 0.0 21.0 1.6 0.0 1.0 1.2 6.8 12.7 0.3 0.0 0.0 2.7 0.3 0.0 1.2 0.0 9.5 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.8 1.1 0.2 0.0 0.1 0.0 0.0 0.0 18.2 0.0 0.0 0.0 29.6 0.0 0.0 0.3 1.8 0.0 1.7 0.0 0.0 52.9 0.0 12.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 6.0 3.5 0.9 3.7 4.7 1.4 2.2 3.1 4.7 2.2 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239105 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavourable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 20.9 23.7 22.2 20.4 19.5 25.1 18.6 11.1 18.9 25.2 32.0 22.7 28.8 19.8 24.7 18.4 17.4 24.3 29.6 29.5 24.1 10.3 23.9 17.1 24.9 19.0 27.6 10.4 30.1 22.7 21.6 26.9 31.9 20.4 28.7 13.5 30.7 27.5 24.2 60.0 17.7 23.0 34.7 27.5 28.3 24.5 11.8 24.3 16.0 29.1 19.3 18.3 25.0 18.1 2.6 5.2 7.0 7.6 4.2 4.5 3.3 6.4 13.8 16.6 11.3 8.2 9.8 29.6 29.8 13.9 18.7 11.9 18.9 16.3 18.4 30.5 22.8 24.6 13.6 8.4 6.4 23.8 14.2 19.1 70.0 6.9 16.1 12.6 42.8 13.9 8.9 18.1 7.2 10.0 13.4 7.9 10.2 17.4 9.3 51.0 16.9 21.6 43.9 37.7 4.1 21.7 10.8 8.1 11.8 32.0 19.3 41.6 20.4 23.9 16.9 20.1 23.5 30.7 9.7 22.9 3.8 17.9 5.7 12.0 10.8 5.2 7.6 7.0 4.5 4.4 3.7 2.2 3.7 3.0 5.2 2.6 2.7 3.7 5.2 4.2 7.0 3.9 3.3 3.3 22.2 19.5 11.1 18.9 24.1 10.3 27.6 10.4 20.4 24.3 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "ASC diff: 18.9;HDLM-2: 26.7;HEL: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: , HPA043870: " "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.4 1.4 2.5 18.9 4.9 0.4 3.4 2.9 2.6 1.7 0.1 0.8 0.1 0.8 2.0 0.8 1.5 2.1 1.9 26.7 0.5 54.8 2.9 0.7 3.9 3.7 2.8 4.0 0.9 1.1 1.8 2.4 3.9 6.4 4.7 0.9 0.9 5.2 1.3 1.7 1.9 2.7 0.7 2.0 1.3 1.6 0.9 1.0 1.5 1.0 0.7 6.5 5.0 4.0 1.3 4.1 2.4 1.2 2.2 0.5 5.2 1.8 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79863668-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 5.3" "Cell line enhanced" "Detected in some" "NB-4: 3.5;U-2 OS: 1.1;U-937: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "hippocampal formation: 31.7" HPA048628 Enhanced "HPA048628: " "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-1)" "unprognostic (1.99e-1)" "unprognostic (9.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (3.78e-1)" "unprognostic (3.61e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-5)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" 0.2 0.1 1.5 0.8 2.2 0.6 0.0 0.1 2.4 0.0 0.3 1.1 0.3 0.0 0.1 0.0 0.0 0.0 5.3 1.0 0.9 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.0 0.2 0.3 0.3 1.2 0.0 0.0 0.5 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.5 0.0 0.7 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.7 0.1 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 MAFA "hMafA, RIPE3b1" ENSG00000182759 "MAF bZIP transcription factor A" Q8NHW3 8 143419182-143430406 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 25.6" "Cell line enhanced" "Detected in some" "HaCaT: 2.7;MCF7: 4.4;RH-30: 2.7;SCLC-21H: 6.4;T-47d: 6.1;U-2 OS: 4.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "amygdala: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (5.92e-3)" "unprognostic (9.89e-3)" "unprognostic (2.81e-3)" "unprognostic (1.42e-8)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (6.08e-2)" "unprognostic (5.67e-2)" "unprognostic (4.41e-1)" "unprognostic (3.71e-1)" "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.00e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-2)" 0.2 0.1 2.5 0.1 0.2 0.2 0.1 0.0 0.6 0.2 0.2 0.0 0.0 0.1 0.1 0.3 0.6 0.1 0.1 2.1 0.4 0.2 0.3 0.1 0.7 0.1 0.1 0.2 0.1 2.2 0.2 0.5 1.8 0.9 0.3 0.1 0.7 0.4 0.1 25.6 0.1 0.1 0.1 0.7 0.1 0.1 3.4 0.0 0.4 2.5 5.5 0.4 0.1 0.1 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 2.7 0.9 0.0 0.0 0.1 1.8 0.9 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.0 4.4 0.1 0.6 0.6 0.4 0.6 2.7 0.4 0.0 0.0 6.4 0.2 1.5 0.0 0.0 6.1 0.1 0.0 0.1 4.2 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 2.5 0.2 0.0 0.6 0.4 0.2 0.1 0.2 0.9 0.0 MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371110-60372775 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;fallopian tube: 10.3" "Cell line enriched" "Detected in single" 69 "fHDF/TERT166: 45.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016719 Uncertain "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" 0.4 1.1 4.0 0.3 9.8 0.2 0.9 0.7 6.4 0.5 0.5 0.3 0.0 0.6 0.4 1.3 0.4 10.3 0.4 0.4 3.0 7.8 0.4 0.2 0.3 0.4 1.1 7.6 0.6 0.2 0.2 0.3 0.2 3.3 0.4 0.5 0.1 2.5 0.5 0.2 0.3 0.4 0.2 0.8 0.8 0.6 0.6 5.1 0.0 0.2 0.0 1.4 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 9.8 0.7 6.4 3.0 7.8 1.1 7.6 3.3 5.1 NEUROD1 "BETA2, BHF-1, bHLHa3, MODY6, NeuroD" ENSG00000162992 "Neuronal differentiation 1" Q13562 2 181673088-181680876 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 101.9" "Cell line enriched" "Detected in some" 72 "SCLC-21H: 79.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 4.3" "Region enriched" "Detected in many" 16 "cerebellum: 101.9" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 14 "cerebellum: 242.4" "Region enriched" "Detected in some" 20 "cerebellum: 447.6" "HPA003278, CAB022450" Approved "CAB022450: , HPA003278: AB_1845331" "unprognostic (1.29e-1)" "prognostic favourable (1.34e-4)" "unprognostic (6.92e-3)" "unprognostic (1.27e-1)" 0.2 0.2 6.3 0.2 0.8 0.1 0.2 101.9 5.6 0.2 3.1 0.0 0.0 8.9 0.2 0.1 0.2 0.2 0.0 0.2 4.7 0.4 0.2 0.2 0.2 0.0 0.4 1.2 0.2 13.3 0.0 0.8 0.0 3.9 0.2 1.9 14.4 0.2 0.0 0.2 0.2 5.8 0.0 1.4 0.2 7.6 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 1.1 1.0 3.5 1.8 1.4 1.5 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.6 1.0 0.8 1.1 1.5 1.1 1.1 0.8 0.8 1.0 1.3 1.4 1.8 1.4 1.8 1.0 1.0 0.7 6.3 0.8 101.9 2.5 4.7 0.4 0.4 1.2 3.9 0.0 NKX6-1 "Nkx6.1, NKX6A" ENSG00000163623 "NK6 homeobox 1" P78426 4 84491987-84498450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 6.0;esophagus: 11.0;pancreas: 10.8" "Cell line enhanced" "Detected in some" "AF22: 5.5;HAP1: 8.0;HEK 293: 7.0;HMC-1: 5.4;PC-3: 4.7;U-2197: 8.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons and medulla: 1.7" "Low region specificity" "Detected in some" "HPA036774, CAB070169" Enhanced Supported Nucleoplasm Nucleoplasm "CAB070169: AB_10011794, HPA036774: AB_10673664" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (9.13e-2)" "unprognostic (3.19e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.71e-2)" "unprognostic (2.46e-1)" "unprognostic (2.75e-2)" "unprognostic (3.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.85e-1)" "unprognostic (5.41e-2)" "unprognostic (7.13e-3)" "unprognostic (3.68e-1)" 0.2 0.0 0.3 0.2 2.2 0.0 6.0 1.0 1.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 11.0 0.0 0.2 0.2 0.4 1.3 0.2 0.2 0.2 0.2 2.5 0.2 0.2 10.8 0.0 0.2 0.2 0.9 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.2 0.2 1.3 0.2 1.5 2.1 0.2 0.2 3.7 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 5.5 0.9 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.2 0.0 8.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 4.7 0.0 2.3 0.0 0.0 0.3 1.5 0.0 0.7 0.0 0.0 0.0 0.7 0.1 0.0 2.4 8.8 2.2 0.0 0.0 0.0 1.5 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 1.0 1.1 0.4 1.3 2.5 0.2 0.9 0.2 NUCKS1 NUCKS ENSG00000069275 "Nuclear casein kinase and cyclin dependent kinase substrate 1" Q9H1E3 1 205712819-205750276 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062351, HPA063843" Supported Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA062351: , HPA063843: " "unprognostic (1.68e-1)" "unprognostic (3.92e-1)" "unprognostic (3.38e-1)" "prognostic unfavourable (1.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (5.16e-3)" "unprognostic (1.18e-3)" "unprognostic (1.37e-1)" "unprognostic (5.82e-3)" "unprognostic (7.45e-3)" "unprognostic (1.44e-1)" "unprognostic (2.25e-2)" "unprognostic (7.57e-2)" 25.6 25.3 46.9 17.3 55.5 12.1 31.3 45.0 49.2 33.0 24.2 38.3 18.8 12.5 36.5 27.8 25.3 32.1 22.5 40.6 43.8 35.6 30.9 43.9 20.6 29.4 43.6 47.6 49.1 17.4 50.3 21.0 20.8 32.8 31.9 21.1 21.9 19.0 32.7 43.1 21.7 14.6 42.9 49.1 22.6 17.9 14.2 38.9 35.3 42.5 20.6 24.8 32.0 22.6 7.8 7.4 4.5 4.9 10.7 11.8 4.0 40.6 25.0 67.4 26.6 18.7 25.9 31.8 29.3 30.3 41.2 33.3 13.7 46.9 45.1 17.0 28.5 30.1 51.2 24.6 47.4 21.5 25.6 29.3 22.1 14.9 13.8 46.0 10.5 20.5 22.3 24.5 42.7 32.2 47.0 14.5 32.1 47.0 41.7 23.2 68.8 18.7 43.6 83.1 25.9 23.1 25.1 28.1 51.9 43.3 34.7 23.5 53.0 34.8 32.1 31.7 28.2 36.1 51.8 13.3 15.7 36.4 21.7 26.0 42.6 4.5 3.4 3.7 9.9 4.9 9.6 5.8 9.2 8.6 4.7 7.8 11.5 11.8 0.6 10.7 4.0 7.4 5.5 4.0 46.9 55.5 45.0 36.6 43.8 35.6 43.6 47.6 32.8 38.9 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533083-71575897 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: " "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavourable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favourable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavourable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favourable (6.85e-7)" 26.1 24.0 33.3 39.7 36.6 38.7 33.7 75.7 43.8 25.0 23.0 22.0 31.1 22.5 36.7 48.3 24.3 33.4 21.2 25.1 29.3 15.4 27.4 20.3 31.0 47.9 30.2 25.6 42.8 46.1 26.5 34.5 19.5 26.6 34.2 30.3 29.9 35.9 30.9 35.0 45.4 38.4 31.1 32.3 56.7 28.2 11.8 36.6 35.7 34.1 27.6 41.4 24.9 31.0 9.7 7.6 3.2 7.2 12.5 9.9 6.0 14.3 13.5 17.5 15.3 18.9 17.4 11.8 11.0 19.9 12.0 18.5 14.2 16.5 17.1 7.8 13.5 17.9 19.1 10.8 14.8 14.6 19.6 10.8 32.1 10.1 14.3 22.2 17.9 16.6 22.0 13.1 24.8 11.1 10.9 59.5 11.4 12.2 17.1 26.7 11.6 18.4 17.0 19.6 21.9 18.5 16.7 9.0 7.9 17.1 11.4 10.6 8.4 15.1 12.9 13.0 10.6 13.5 6.4 16.3 11.7 20.6 9.1 23.4 7.9 3.2 5.3 2.3 9.9 7.2 9.0 9.7 8.3 8.0 7.5 8.5 9.7 9.5 2.4 12.5 6.5 7.6 7.6 6.0 33.3 36.6 75.7 43.8 29.3 15.4 30.2 25.6 26.6 36.6 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1, mitochondrial dynamin like GTPase" O60313 3 193593144-193697823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria 13000 "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: " "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavourable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favourable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 17.0 19.7 18.2 13.5 31.7 25.9 15.9 20.2 30.9 13.9 21.8 11.1 12.6 20.0 15.2 11.8 18.8 11.8 12.8 43.9 23.0 19.4 21.8 24.1 10.7 15.3 19.0 22.4 13.2 13.4 20.9 15.6 13.8 28.0 15.5 20.5 9.1 15.7 20.8 38.4 14.6 17.3 16.5 17.0 13.1 16.7 7.6 10.8 18.0 16.8 18.4 14.2 16.5 13.6 8.3 8.8 8.2 17.6 5.0 7.5 5.9 25.9 8.3 8.5 9.3 7.5 11.9 9.0 12.6 11.6 13.9 13.6 20.3 8.8 17.3 27.3 11.8 16.9 14.8 14.3 24.6 20.8 12.0 29.9 7.4 10.1 11.7 24.5 13.8 13.2 12.8 13.4 19.0 11.7 12.6 17.0 13.8 20.5 9.5 13.6 11.9 27.9 12.5 18.6 18.5 10.4 16.2 18.5 11.2 18.9 21.1 13.4 27.7 19.4 11.7 12.9 9.8 13.8 26.5 15.3 17.8 33.8 14.2 19.7 12.9 8.2 8.1 7.7 7.2 9.3 6.6 8.3 6.8 6.8 8.8 6.3 6.9 7.3 3.2 5.0 17.6 4.6 7.5 5.9 18.2 31.7 20.2 30.9 23.0 19.4 19.0 22.4 28.0 10.8 OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavourable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" 29.3 11.4 13.9 18.4 41.9 23.1 17.2 13.7 20.2 20.0 11.5 6.8 8.4 7.5 18.5 10.7 20.1 10.4 15.0 19.3 13.4 12.9 30.2 15.2 20.5 22.7 12.1 13.2 14.9 11.2 12.4 16.5 14.4 13.9 16.2 9.7 9.2 15.8 11.1 21.5 22.9 12.6 15.5 14.8 24.9 12.4 12.8 14.7 41.0 11.7 10.6 24.8 18.0 24.5 11.7 15.8 57.2 15.0 9.9 10.9 8.1 12.3 7.9 17.6 12.5 24.6 34.8 11.2 19.1 26.7 12.2 11.2 11.4 5.1 17.3 10.9 22.6 5.2 13.1 11.0 18.5 14.8 11.6 46.5 7.8 6.8 15.2 29.4 19.0 18.3 21.0 18.2 22.8 10.5 31.8 8.0 20.1 8.5 19.6 14.0 8.6 7.9 10.3 24.1 9.9 9.4 10.5 9.7 10.1 16.3 6.0 11.8 4.5 18.0 24.6 19.9 9.9 20.4 10.2 8.0 12.6 19.1 7.5 16.6 11.5 27.5 15.0 20.1 9.0 10.8 8.5 11.7 9.6 7.3 13.2 11.6 8.7 7.1 57.2 9.9 11.7 15.8 10.9 8.1 13.9 41.9 13.7 19.9 13.4 12.9 12.1 13.2 13.9 14.7 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell line enhanced" "Detected in many" "U-266/70: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.8 8.0 17.4 7.8 7.1 11.9 13.9 13.6 9.7 12.9 15.2 11.4 15.9 10.6 5.0 11.7 6.1 12.1 14.4 20.4 12.2 9.8 11.2 5.4 0.7 4.7 18.9 16.6 8.8 8.7 15.1 22.5 3.0 7.4 18.7 23.4 0.8 12.0 8.7 25.7 6.9 18.5 22.5 0.4 3.3 9.9 7.5 7.4 7.3 3.1 5.7 13.9 8.6 0.2 8.6 14.9 45.9 11.3 51.4 26.4 7.0 7.2 12.6 9.3 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199, HPA068961" Supported Approved Vesicles Vesicles "CAB004272: AB_626657, HPA035199: , HPA068961: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favourable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.4 10.8 13.5 9.0 14.0 11.7 14.3 14.0 9.1 12.6 10.6 10.8 10.1 13.9 9.6 13.6 13.4 16.1 10.1 12.0 24.7 10.9 7.3 14.3 17.9 12.2 12.1 19.4 10.6 18.6 13.5 9.1 11.5 13.6 11.3 14.7 17.8 12.2 8.5 8.5 9.7 25.0 13.5 12.5 12.2 7.5 21.3 11.0 18.2 21.0 7.5 19.4 15.3 14.1 13.8 13.7 13.4 12.1 15.1 14.3 21.7 6.6 8.4 11.9 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 20.9;hTEC/SVTERT24-B: 32.2;LHCN-M2: 21.3;REH: 22.4;RH-30: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 23.5;intermediate monocyte: 26.5;myeloid DC: 28.1" "Group enriched" "Detected in many" 58 "dendritic cells: 28.1;monocytes: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 18.9 24.8 21.4 11.3 12.7 2.5 29.6 2.7 34.4 17.8 19.4 3.9 12.1 4.9 13.8 16.0 11.6 15.5 14.1 11.5 13.6 11.7 5.3 52.4 22.8 18.8 15.7 16.7 27.1 11.4 1.8 5.3 20.9 11.9 16.6 18.2 17.9 5.8 13.1 14.6 11.4 13.8 27.8 6.2 15.6 15.6 6.2 6.2 0.1 9.8 8.9 3.4 16.8 50.6 0.0 28.1 0.4 26.5 0.0 0.1 8.1 0.0 0.7 0.0 0.0 20.9 4.0 0.0 3.3 12.8 2.2 2.7 0.2 0.0 0.0 0.1 4.7 0.6 0.0 0.6 3.0 0.0 0.0 0.0 1.5 0.0 8.6 0.0 0.0 7.6 5.8 32.2 5.3 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.3 1.9 22.4 34.2 0.0 0.4 0.0 0.7 0.8 7.1 0.6 0.0 0.0 0.0 0.0 8.5 3.2 7.9 3.1 0.0 0.0 0.0 11.1 0.0 1.3 0.0 23.5 0.0 0.0 26.5 0.1 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.4 0.0 5.1 0.1 0.1 8.1 21.4 12.7 2.7 15.1 13.6 11.7 15.7 16.7 11.9 6.2 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Enzymes, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm Nucleoplasm "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favourable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.3 16.8 17.6 17.2 26.3 9.2 20.0 22.6 17.2 22.1 17.2 13.9 22.2 15.6 20.3 19.2 16.8 18.2 20.2 16.3 14.5 11.6 25.7 16.3 22.2 11.3 17.6 16.1 17.6 14.2 62.9 23.0 23.5 28.5 18.7 14.3 15.2 15.6 27.5 15.4 13.1 17.9 19.5 31.8 17.5 18.3 19.4 18.0 11.4 32.2 9.3 11.5 23.1 20.5 4.4 5.2 6.0 7.2 4.2 4.8 1.6 22.8 10.5 17.6 10.9 12.7 13.0 15.7 14.5 15.7 10.6 14.9 25.4 2.6 6.7 7.2 12.4 15.2 14.0 11.0 19.0 5.7 12.1 4.1 12.7 9.9 13.9 5.2 6.7 10.1 7.8 10.5 20.6 25.3 9.8 6.5 8.2 7.1 2.8 3.2 10.0 8.1 2.9 18.3 4.6 13.2 20.3 10.4 9.2 22.0 9.5 10.2 5.6 5.3 31.5 8.6 12.4 22.2 8.8 2.6 5.8 5.5 10.2 4.9 9.9 4.1 4.1 2.9 4.6 2.5 3.0 3.6 3.7 3.6 5.2 4.4 4.8 2.8 6.0 4.2 7.2 3.7 2.3 1.6 17.6 26.3 22.6 17.2 14.5 11.6 17.6 16.1 28.5 18.0 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Approved Cytosol Cytosol "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 20.1 12.3 13.7 11.5 13.4 25.7 22.4 17.1 24.5 12.9 14.0 5.2 5.7 6.5 15.3 7.9 11.6 11.1 13.2 14.2 18.4 9.7 11.7 10.8 13.2 13.8 9.8 15.7 15.4 9.2 24.7 11.6 16.5 16.3 10.7 8.9 7.2 10.9 10.9 15.2 12.0 10.5 12.8 14.4 16.2 10.6 9.3 9.8 29.6 11.0 7.3 13.9 15.1 15.7 6.2 2.6 7.8 3.8 2.4 5.0 1.1 14.4 4.9 7.9 7.3 18.7 21.8 5.7 9.2 12.5 9.1 14.4 4.2 10.7 13.2 15.8 11.0 5.9 6.4 8.0 13.2 22.0 5.7 18.1 5.3 3.7 8.9 10.1 10.3 13.7 8.5 10.0 11.5 13.0 9.0 14.7 13.0 5.7 7.7 9.1 6.2 6.7 11.8 8.0 15.8 7.2 8.8 4.4 7.6 10.0 8.9 12.0 14.9 8.7 13.8 8.6 5.6 13.5 9.2 7.1 10.1 23.7 7.7 7.6 5.0 2.1 3.8 1.6 5.0 2.9 3.9 5.8 4.2 2.8 2.2 6.2 4.6 3.8 7.8 2.4 3.0 2.6 4.1 1.1 13.7 13.4 17.1 24.5 18.4 9.7 9.8 15.7 16.3 9.8 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.6" "Group enriched" "Detected in many" 8 "granulocytes: 8.6;monocytes: 3.1;T-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: " "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favourable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favourable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 33.7 10.9 7.4 7.0 8.2 0.8 24.7 36.4 11.0 16.9 6.3 3.5 9.1 3.3 15.8 11.0 8.4 7.6 10.9 28.7 6.8 8.5 10.4 4.1 20.0 6.0 8.7 3.1 4.6 4.0 18.7 10.2 13.4 10.4 9.0 5.3 13.6 9.4 8.0 14.8 4.6 6.0 12.3 7.1 10.9 7.4 24.0 4.5 5.9 12.7 6.2 5.3 12.3 8.7 0.5 0.6 8.6 3.1 0.1 3.5 0.9 4.6 1.6 21.4 10.8 2.1 0.9 6.8 2.8 2.0 3.7 4.6 0.9 1.4 6.1 8.5 1.0 2.8 7.4 2.5 2.4 4.8 6.7 3.8 19.2 0.7 0.7 3.5 5.3 2.6 1.5 3.9 1.4 7.6 1.4 4.4 5.2 7.1 14.0 2.1 7.5 4.3 18.0 5.7 7.3 9.2 33.3 15.5 11.2 9.0 23.9 2.5 6.6 3.1 14.2 3.9 3.7 0.6 2.7 6.3 6.5 3.7 3.1 4.7 2.0 0.0 0.3 8.6 3.3 0.5 3.0 0.5 0.8 2.9 0.0 0.0 0.3 1.9 0.1 0.1 3.1 0.6 3.5 0.9 7.4 8.2 36.4 8.9 6.8 8.5 8.7 3.1 10.4 4.5 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 541.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol 540000000 Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (1.30e-4)" "prognostic unfavourable (2.74e-6)" "prognostic unfavourable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavourable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 23.2 76.8 53.8 49.8 70.4 57.5 41.6 56.6 85.9 65.7 31.2 32.1 31.5 26.4 24.7 41.8 76.4 37.9 32.9 94.8 50.1 57.1 60.9 6.1 33.3 39.4 62.5 63.6 26.2 15.6 33.3 28.3 27.1 80.5 34.8 31.9 54.4 47.1 47.5 541.2 51.8 25.1 44.7 34.9 30.7 26.7 29.0 29.4 23.5 23.8 114.4 60.6 53.1 40.9 25.1 79.6 14.9 90.6 11.6 37.4 114.9 81.5 209.8 42.3 50.0 50.9 57.2 35.0 88.5 206.7 142.1 143.9 59.0 100.5 62.1 89.6 165.6 118.9 133.7 180.0 111.4 109.0 63.2 38.0 105.5 48.8 35.5 49.3 82.0 51.9 83.9 109.5 45.0 83.6 9.5 49.8 224.1 50.7 18.4 21.2 52.3 80.1 54.7 135.4 118.3 188.7 105.0 44.0 48.0 115.4 71.2 90.5 49.9 35.9 65.1 161.9 88.6 158.2 160.5 64.0 90.4 54.7 199.3 81.6 158.6 12.6 90.6 14.9 23.5 52.6 22.8 25.1 31.3 23.2 79.6 16.1 27.3 20.2 11.8 11.6 40.2 16.2 37.4 114.9 53.8 70.4 56.6 85.9 50.1 57.1 62.5 63.6 80.5 29.4 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria Mitochondria "HPA008233: AB_1855661, HPA008823: " "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavourable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favourable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.9 17.0 5.7 25.4 10.3 15.3 13.5 24.4 23.8 12.6 7.3 9.6 12.7 16.4 16.0 15.1 26.8 16.3 16.3 22.0 11.9 9.0 20.1 34.8 6.0 14.3 14.9 7.7 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.9 12.9 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.6 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 63.3;THP-1: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavourable (2.24e-4)" "prognostic favourable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.7 3.0 1.2 2.0 9.0 5.2 11.2 4.7 5.9 5.8 5.7 7.3 7.6 20.0 2.1 10.2 3.5 7.9 11.5 4.7 17.4 6.0 11.1 4.1 7.8 5.7 14.6 25.1 4.1 8.4 5.9 5.5 5.0 2.2 2.9 8.3 19.1 1.6 24.9 3.1 5.5 1.7 3.0 4.7 6.3 16.7 2.0 1.4 3.6 63.3 9.7 5.3 45.2 7.2 2.8 3.6 3.7 4.4 4.4 6.8 10.2 6.7 25.2 5.4 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888731-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" 330000 Cytosol "Plasma membrane" "HPA040512: AB_2677014, HPA044220: AB_2678860" "unprognostic (2.24e-1)" "unprognostic (2.48e-3)" "unprognostic (2.12e-1)" "unprognostic (3.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.51e-1)" "prognostic unfavourable (1.32e-5)" "unprognostic (1.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (9.64e-3)" "unprognostic (3.17e-2)" "unprognostic (5.73e-2)" "unprognostic (6.19e-2)" "unprognostic (8.63e-2)" 25.6 10.7 11.5 12.9 12.1 27.8 18.7 15.3 12.0 9.6 22.1 9.2 14.8 19.5 14.4 13.6 12.3 10.7 12.5 13.9 10.6 11.2 19.2 19.8 12.3 14.8 10.6 9.0 13.0 28.6 4.9 8.3 8.7 12.7 9.5 4.8 9.4 15.3 14.2 28.6 12.4 16.3 15.7 11.6 14.8 24.7 13.6 8.7 13.8 10.9 17.1 9.2 8.2 11.8 24.5 36.7 29.6 26.3 14.9 25.9 27.3 20.5 31.6 2.6 4.8 4.4 4.5 5.5 21.0 6.8 10.5 6.0 23.0 2.5 15.3 17.8 10.8 8.4 7.5 11.0 6.3 29.6 16.6 12.5 14.7 11.4 11.0 8.8 8.9 8.0 5.2 11.8 4.5 6.3 11.2 2.2 6.6 24.1 17.5 6.6 5.5 24.7 13.4 7.2 9.4 5.1 20.7 5.5 7.7 21.1 3.1 11.3 9.1 4.4 16.6 10.1 11.6 19.7 14.6 12.0 25.9 22.3 18.1 11.5 9.2 20.3 26.3 29.6 20.9 25.4 16.7 24.5 20.1 18.9 22.2 19.5 15.8 13.6 24.1 14.9 22.0 36.7 25.9 27.3 11.5 12.1 15.3 12.0 10.6 11.2 10.6 9.0 12.7 8.7 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase, non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favourable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 16.7 12.5 12.6 27.0 14.3 33.7 19.9 32.6 19.2 14.7 15.0 7.8 17.8 12.9 12.2 14.9 17.0 13.7 15.7 12.8 13.1 6.8 13.6 20.5 21.6 30.3 15.3 10.3 22.1 28.2 10.4 27.2 13.3 13.8 14.4 17.1 7.9 26.3 16.0 13.1 16.0 15.3 11.8 24.7 24.2 13.1 9.4 15.9 61.3 14.7 11.7 28.9 16.5 15.8 29.1 32.8 19.9 28.0 31.7 29.2 19.6 13.0 7.9 9.3 3.1 10.6 19.2 9.0 8.7 19.4 18.7 16.8 17.2 18.9 20.5 14.7 9.0 7.8 15.1 23.9 24.7 7.9 9.1 14.5 6.9 17.9 14.7 33.9 13.8 16.1 22.7 17.0 33.8 9.5 14.0 27.9 15.0 14.9 33.8 28.0 11.1 9.3 11.4 14.6 23.2 15.7 20.9 16.7 8.7 17.7 10.4 15.1 8.7 19.5 7.2 23.8 23.0 17.7 18.8 8.9 8.9 29.6 11.2 18.7 9.9 11.5 28.0 19.9 21.0 24.6 28.2 29.1 24.8 23.1 32.8 20.3 18.3 20.0 10.2 31.7 22.8 28.0 29.2 19.6 12.6 14.3 32.6 19.2 13.1 6.8 15.3 10.3 13.8 15.9 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase, receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.7;SK-BR-3: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" 95000000 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favourable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 37.1 5.5 22.4 10.4 18.1 0.9 30.7 6.8 19.5 14.2 34.3 16.8 34.4 30.7 12.3 33.4 41.4 32.2 20.0 6.3 17.2 15.0 12.0 45.6 15.7 5.8 17.2 18.5 10.4 25.3 17.5 10.3 38.1 16.1 30.9 23.1 5.9 41.9 23.6 2.9 46.8 35.5 16.8 11.2 2.0 21.8 4.3 15.8 4.6 12.5 11.7 14.9 21.4 21.3 0.9 0.0 0.2 0.0 0.0 0.0 0.7 30.4 14.6 9.6 11.3 2.2 0.1 53.7 17.5 7.0 14.5 12.4 15.5 41.5 0.0 4.9 7.6 23.9 11.1 38.5 17.6 0.3 13.9 0.1 10.0 14.1 6.8 0.2 0.2 2.2 22.2 20.8 34.6 21.5 4.7 1.4 5.3 17.6 0.2 0.2 14.5 4.0 10.6 17.0 0.7 5.6 46.1 14.3 5.3 17.4 61.4 2.3 17.7 3.2 16.9 0.3 23.2 1.4 23.3 0.6 0.5 0.0 1.4 0.7 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 22.4 18.1 6.8 19.5 17.2 15.0 17.2 18.5 16.1 15.8 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.6;brain: 70.9" "Cell line enhanced" "Detected in some" "Karpas-707: 17.6;SCLC-21H: 6.8;U-266/70: 9.0;U-266/84: 17.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 68.3;basal ganglia: 31.5;cerebral cortex: 55.3;hippocampal formation: 70.9;olfactory region: 23.8" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: " "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favourable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 3.3 29.6 68.3 1.6 31.5 0.6 5.2 10.9 55.3 4.9 1.5 5.4 1.0 2.1 6.6 2.7 2.3 2.9 3.7 5.7 70.9 10.2 3.8 24.6 5.4 1.7 10.0 23.8 9.7 2.0 3.2 2.4 2.3 8.6 3.5 1.7 11.3 1.7 2.9 1.4 10.6 1.8 4.3 2.9 0.9 5.4 3.7 11.5 0.0 4.3 0.9 1.8 4.2 1.2 0.4 0.6 1.4 0.6 0.6 0.7 0.1 0.1 0.1 2.6 0.4 0.0 0.2 0.1 0.9 0.5 0.1 0.2 0.0 3.0 0.0 0.2 0.0 0.5 2.2 0.6 0.3 0.1 4.7 0.4 2.2 0.0 0.0 2.9 0.7 0.0 0.7 0.0 0.0 2.8 0.0 17.6 0.1 0.0 0.2 0.2 0.3 0.3 0.0 0.6 0.0 0.0 5.2 6.8 2.5 0.1 0.0 0.9 0.1 0.1 0.8 0.1 0.3 0.0 0.2 9.0 17.6 0.0 0.3 0.1 0.1 1.4 0.4 0.4 0.3 0.4 0.6 0.4 0.4 0.3 0.3 0.4 0.6 0.7 1.0 0.6 0.6 0.6 0.3 0.1 68.3 31.5 10.9 55.3 70.9 10.2 10.0 23.8 8.6 11.5 RELA "NFKB3, p65" ENSG00000173039 "RELA proto-oncogene, NF-kB subunit" Q04206 11 65653596-65663094 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004264, CAB005030, HPA063461" Supported Enhanced Cytosol Cytosol "CAB004264: AB_628017, CAB005030: AB_562171, HPA063461: " "unprognostic (9.17e-2)" "unprognostic (1.79e-1)" "unprognostic (2.04e-1)" "unprognostic (3.22e-1)" "unprognostic (7.67e-2)" "unprognostic (5.39e-2)" "prognostic unfavourable (9.18e-4)" "unprognostic (1.30e-3)" "unprognostic (1.69e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" "unprognostic (2.37e-1)" "prognostic unfavourable (5.66e-4)" "unprognostic (2.78e-1)" "unprognostic (1.46e-1)" "unprognostic (9.81e-2)" "unprognostic (2.53e-1)" 36.2 23.1 21.4 27.6 32.0 50.2 37.8 21.5 28.2 35.6 32.3 22.9 23.6 23.6 36.9 26.8 36.4 32.8 33.6 28.9 21.1 12.9 28.4 38.5 37.7 30.8 35.6 13.3 51.9 29.0 27.3 19.3 27.1 22.6 31.1 19.7 23.9 32.8 39.2 46.5 35.2 26.7 33.5 29.5 38.1 31.8 20.6 30.1 34.3 26.3 30.6 36.4 54.7 38.8 15.2 13.2 18.3 14.4 21.3 23.3 12.4 26.1 26.9 12.0 16.7 19.2 18.7 12.2 20.1 24.4 23.2 18.8 12.2 26.6 19.8 33.8 28.2 23.4 13.8 24.4 16.4 23.3 19.9 21.8 20.1 17.7 21.2 16.1 30.9 21.5 24.1 25.8 30.6 28.1 21.8 23.1 18.6 34.9 29.2 13.6 7.8 23.7 24.4 11.8 29.6 19.4 23.7 9.9 22.8 17.2 27.0 26.8 31.4 10.6 38.3 25.1 21.5 38.3 19.1 35.0 32.2 21.1 28.4 11.1 23.9 10.5 11.3 15.1 20.5 14.4 23.3 15.2 18.2 20.4 13.2 13.7 17.3 18.2 18.3 21.3 12.5 13.1 17.8 12.4 21.4 32.0 21.5 28.2 21.1 12.9 35.6 13.3 22.6 30.1 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46583121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 62.0;ASC TERT1: 48.5;SK-MEL-30: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA044938: " "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavourable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 43.3 13.1 20.9 14.1 19.4 4.9 16.7 6.5 15.1 16.4 16.6 12.7 11.7 4.9 15.5 32.9 9.8 13.8 15.0 65.2 16.8 13.0 13.9 6.0 14.2 10.0 19.5 14.9 16.0 12.9 20.4 8.2 13.8 20.4 14.6 6.9 16.0 9.6 19.2 63.8 7.2 8.9 19.3 15.4 13.2 9.3 6.3 13.4 8.0 18.0 17.2 9.1 17.7 12.1 3.9 2.9 8.9 4.8 0.7 0.8 1.3 4.1 4.3 7.2 10.1 62.0 48.5 0.9 11.9 30.1 5.8 9.1 2.0 1.3 10.1 13.0 21.0 1.7 7.5 3.5 10.6 3.4 5.1 2.3 3.2 7.0 30.3 3.0 3.6 42.9 6.1 7.7 8.3 6.8 4.0 16.8 12.5 2.8 2.3 5.4 7.5 5.4 1.6 13.1 3.4 7.9 8.0 5.7 18.5 4.4 5.9 52.7 3.2 6.9 4.7 19.0 17.7 18.5 4.8 17.3 6.2 10.6 27.7 7.4 6.7 2.7 4.6 7.8 0.7 4.8 0.6 3.4 0.4 0.8 2.9 3.9 0.1 0.6 8.9 0.7 3.4 1.3 0.6 1.3 20.9 19.4 6.5 15.1 16.8 13.0 19.5 14.9 20.4 13.4 RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin/insulin like family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;placenta: 12.2" "Group enriched" "Detected in some" 4 "EFO-21: 23.6;HEL: 7.8;RPTEC TERT1: 10.9" "Cancer enriched" "Detected in single" 9 "endometrial cancer: 3.9" "Group enriched" "Detected in many" 6 "basal ganglia: 10.4;cerebral cortex: 18.5;olfactory region: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA027067 Approved "HPA027067: AB_10602127" "unprognostic (3.07e-3)" "unprognostic (3.02e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-3)" "unprognostic (6.13e-2)" "unprognostic (6.18e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-6)" "unprognostic (8.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.33e-4)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (6.22e-3)" 0.5 6.5 2.1 0.5 10.4 0.2 0.4 0.4 19.7 4.0 0.5 0.0 1.1 0.3 9.0 1.6 0.5 1.3 1.2 0.4 2.0 1.7 2.9 2.1 5.1 0.7 0.8 12.4 0.8 0.6 0.2 0.6 12.2 0.0 1.0 0.3 0.6 0.4 4.2 0.4 0.4 0.9 1.3 0.4 0.6 0.6 0.6 0.0 0.0 2.4 0.0 0.6 0.5 2.2 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 10.4 0.4 18.5 2.0 1.7 0.8 12.4 0.0 0.0 RXFP2 "GPR106, GREAT, INSL3R, LGR8, RXFPR2" ENSG00000133105 "Relaxin/insulin like family peptide receptor 2" Q8WXD0 13 31739542-31803388 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.3;epididymis: 28.4" "Group enriched" "Detected in some" 6 "U-2197: 2.1;U-87 MG: 4.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "basal ganglia: 8.3" "Cell type enriched" "Detected in single" 11 "classical monocyte: 5.0" "Lineage enriched" "Detected in single" 23 "monocytes: 5.0" "Low region specificity" "Detected in single" "Region enriched" "Detected in single" 7 "basal ganglia: 2.0" "unprognostic (1.77e-2)" 0.5 3.3 1.5 0.1 8.3 2.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 28.4 0.0 1.5 0.1 0.5 0.6 0.5 0.3 0.0 0.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.6 0.0 0.2 0.0 3.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 5.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 5.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 1.5 8.3 0.0 0.5 0.6 0.5 0.0 0.0 0.5 0.0 RXFP3 "GPCR135, RLN3R1, RXFPR3, SALPR" ENSG00000182631 "Relaxin/insulin like family peptide receptor 3" Q9NSD7 5 33936386-33938237 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 3.1;brain: 1.1;pancreas: 1.7;pituitary gland: 1.1" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA027833 Uncertain "HPA027833: AB_1849247" "unprognostic (1.93e-2)" "unprognostic (3.66e-1)" "unprognostic (2.89e-1)" "unprognostic (2.86e-1)" "unprognostic (9.68e-2)" "unprognostic (1.72e-1)" "unprognostic (8.67e-3)" 0.0 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RXFP4 "GPCR142, GPR100, RLN3R2, RXFPR4" ENSG00000173080 "Relaxin/insulin like family peptide receptor 4" Q8TDU9 1 155941710-155942949 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 1.8;bone marrow: 1.3;intestine: 5.4" "Cell line enhanced" "Detected in some" "Hep G2: 1.6;NB-4: 2.1;SK-MEL-30: 2.0;T-47d: 2.2" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.4" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (3.64e-2)" "unprognostic (1.84e-3)" "unprognostic (2.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.17e-2)" "unprognostic (4.73e-2)" "unprognostic (2.87e-1)" "unprognostic (8.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (3.86e-2)" 0.2 0.0 0.0 0.5 0.1 1.3 0.1 0.7 0.0 0.0 5.2 3.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 0.1 0.1 0.0 0.0 2.8 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.6 0.4 1.8 1.4 0.7 0.8 0.2 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.4 1.2 0.0 0.9 0.0 0.3 0.0 0.0 0.3 0.6 0.2 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 0.1 2.1 0.3 0.0 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 1.0 2.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.1 1.2 0.7 1.2 0.2 0.1 0.0 0.9 1.8 0.0 1.1 0.0 0.0 0.5 0.8 0.4 0.6 0.0 0.1 1.1 0.7 1.4 0.0 0.0 0.2 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925375-42959176 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease mutation, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 194.0" "Cell line enhanced" "Detected in many" "BEWO: 44.2;CACO-2: 71.8;Hep G2: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" 36000000 "Plasma membrane" "CAB002759: , HPA031345: , HPA058494: " "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavourable (3.65e-8)" "prognostic unfavourable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavourable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavourable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (4.05e-4)" 4.2 3.7 12.4 3.9 16.9 45.2 4.1 6.7 15.5 15.2 4.8 15.1 4.3 2.4 7.6 3.4 28.8 8.5 8.6 5.0 15.4 13.7 7.6 2.1 2.4 5.3 18.2 5.0 3.4 3.7 7.3 2.9 194.0 15.5 5.2 3.3 44.2 8.4 7.9 1.8 42.1 2.9 2.5 17.8 3.4 5.5 2.5 12.5 1.8 4.0 11.5 12.0 22.2 24.5 8.4 14.7 1.3 0.2 3.0 7.5 2.7 10.6 15.3 12.7 3.2 1.5 0.5 44.2 7.0 15.2 8.6 12.8 71.8 29.7 4.0 21.0 2.1 9.9 2.8 16.3 3.8 2.4 2.6 6.6 8.9 49.0 4.4 3.6 1.9 1.8 12.6 5.4 5.9 1.4 14.8 0.9 3.9 18.9 1.6 2.5 8.1 3.9 1.6 4.1 5.6 7.9 5.2 6.7 4.7 8.2 26.0 3.0 1.1 4.6 3.2 7.9 5.7 1.4 15.8 0.7 1.5 2.4 15.6 2.5 6.4 0.3 0.2 1.3 7.5 0.2 6.9 8.4 4.1 5.1 2.9 7.3 3.2 4.7 1.0 3.0 0.1 14.7 4.7 2.7 12.4 16.9 6.7 15.5 15.4 13.7 18.2 5.0 15.5 12.5 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027408-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.9 13.6 17.1 12.7 18.3 11.6 23.5 25.7 21.9 13.2 22.7 16.7 9.5 19.7 14.2 8.9 15.9 11.4 13.9 15.1 16.2 14.3 15.7 9.8 14.1 14.7 16.3 14.5 18.3 17.7 13.7 8.4 9.5 13.4 15.1 11.6 11.2 15.6 15.4 25.2 17.2 20.4 15.0 17.6 11.3 13.5 7.6 15.8 12.4 14.4 10.1 11.5 14.9 12.5 7.7 8.0 10.9 18.3 3.2 7.1 5.7 17.4 12.9 8.4 8.2 10.1 7.5 4.7 1.7 7.9 13.8 12.7 10.1 13.7 17.8 9.9 9.9 9.8 9.8 8.7 3.8 26.7 8.1 8.9 10.6 16.9 11.0 4.6 14.4 6.3 13.0 14.6 8.4 8.2 15.0 11.4 7.2 10.5 16.3 20.7 9.0 12.8 13.5 5.0 19.1 10.2 3.8 15.2 11.4 14.9 13.5 12.9 13.6 10.7 16.1 14.0 13.4 14.1 7.4 12.3 21.0 17.0 13.7 7.3 4.8 7.8 11.3 10.9 6.9 13.6 5.6 7.7 7.1 6.1 8.0 6.1 5.2 4.7 1.6 3.2 18.3 5.5 6.7 5.7 17.1 18.3 25.7 21.9 16.2 14.3 16.3 14.5 13.4 15.8 SNX4 ATG24B ENSG00000114520 "Sorting nexin 4" O95219 3 125446644-125520197 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005709 Uncertain "HPA005709: AB_1080049" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (1.91e-2)" "prognostic unfavourable (6.10e-4)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (1.19e-2)" "unprognostic (6.33e-2)" "unprognostic (4.93e-2)" "unprognostic (4.06e-1)" "unprognostic (3.42e-1)" "unprognostic (6.99e-2)" "prognostic favourable (5.01e-5)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" 18.8 22.1 19.9 18.3 17.3 11.5 21.1 20.3 20.2 17.8 24.6 16.7 10.8 28.8 17.6 13.6 15.1 12.5 16.5 17.1 20.8 20.4 43.1 45.2 15.7 14.2 20.1 17.6 15.6 18.5 13.3 19.3 26.1 18.7 19.5 23.2 11.7 17.8 14.7 32.4 10.2 38.7 17.3 27.7 15.0 17.4 14.4 13.3 20.5 37.3 10.8 13.6 14.0 13.5 12.3 15.6 21.0 15.7 14.4 15.1 10.7 16.8 5.4 17.5 10.9 10.9 9.1 19.9 9.2 8.7 18.3 16.5 11.6 7.7 10.7 10.9 11.1 9.0 16.2 7.8 22.0 10.0 11.9 17.3 7.5 17.5 12.8 18.2 11.3 11.8 8.6 9.2 7.5 17.1 18.5 5.5 13.9 12.6 19.9 12.3 10.2 6.5 18.5 21.3 19.6 16.9 15.1 18.4 26.0 14.8 19.3 22.6 19.0 30.0 11.0 9.2 11.7 11.9 10.7 11.2 9.5 29.6 11.3 11.7 13.9 9.3 12.4 21.0 9.0 15.7 11.8 12.3 11.6 10.2 15.6 9.5 15.1 12.9 2.2 14.4 15.1 13.8 12.7 10.7 19.9 17.3 20.3 20.2 20.8 20.4 20.1 17.6 18.7 13.3 SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 38.5;K-562: 31.3;REH: 74.1;THP-1: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 45.5" "Lineage enhanced" "Detected in many" "granulocytes: 45.5" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favourable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favourable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" 25.2 14.3 2.6 5.1 4.1 3.6 39.6 2.3 4.3 37.9 14.2 2.4 23.1 4.3 38.8 21.4 7.7 15.0 15.5 12.4 4.9 3.1 14.6 28.2 22.7 12.3 3.3 1.4 14.1 7.1 18.7 26.7 21.9 11.0 33.5 6.9 7.0 4.9 32.5 12.0 3.7 10.7 36.9 3.3 4.3 12.3 10.3 2.9 12.7 12.7 7.1 4.3 15.6 21.3 0.8 0.6 45.5 0.1 8.2 11.5 5.1 0.7 1.0 3.9 3.4 2.2 4.0 4.4 4.8 17.5 3.4 1.6 38.5 1.7 0.2 0.1 4.4 8.9 20.2 1.4 4.1 15.5 0.5 3.1 0.1 0.5 3.3 0.9 6.7 6.5 1.1 4.0 5.4 0.5 31.3 0.6 0.5 0.4 0.1 1.4 11.0 1.6 74.1 0.0 0.8 0.9 1.6 6.6 8.0 1.6 2.7 12.4 0.0 31.9 0.5 10.4 0.2 0.0 2.6 0.4 0.2 0.2 0.2 2.4 6.6 45.5 0.0 2.2 8.4 0.1 11.5 0.1 10.5 7.7 0.0 0.8 10.7 6.3 0.3 8.2 0.1 0.6 6.0 5.1 2.6 4.1 2.3 4.3 4.9 3.1 3.3 1.4 11.0 2.9 SRSF5 "HRS, SFRS5, SRP40" ENSG00000100650 "Serine and arginine rich splicing factor 5" Q13243 14 69726900-69772005 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043484, HPA056523" Approved Supported Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA043484: AB_10797143, HPA056523: " "unprognostic (2.08e-3)" "prognostic favourable (7.91e-4)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.30e-3)" "unprognostic (1.07e-3)" "unprognostic (2.37e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (1.00e-2)" 66.6 60.1 67.1 60.9 74.4 131.5 70.3 111.7 88.8 54.3 63.3 67.8 77.1 42.6 71.3 74.6 66.3 79.3 50.1 48.5 66.2 43.0 40.5 60.8 69.4 63.3 86.4 62.1 76.6 41.0 56.4 124.8 59.2 74.0 59.0 54.7 69.2 68.5 75.6 76.0 78.1 74.1 59.7 68.6 66.5 62.0 35.3 75.6 47.8 70.8 52.3 69.1 69.6 55.8 41.2 37.4 60.8 45.1 30.8 38.2 24.4 69.2 20.2 49.6 22.3 30.7 26.5 27.5 33.4 36.0 27.3 29.0 25.4 44.5 71.8 17.7 45.3 33.1 37.5 47.7 32.3 61.3 20.6 54.1 54.3 27.8 35.7 50.4 41.0 55.1 30.4 31.5 33.8 37.8 37.5 42.8 16.9 56.2 57.9 34.2 29.1 18.7 49.7 23.6 27.6 34.7 85.3 25.9 37.0 56.7 34.4 43.1 37.4 42.5 46.6 16.0 42.9 17.4 31.2 41.7 27.2 116.1 37.7 43.0 22.0 39.0 24.1 37.2 37.3 43.4 38.2 41.2 33.2 33.4 26.2 40.6 33.2 31.5 60.8 30.8 45.1 37.4 27.4 24.4 67.1 74.4 111.7 88.8 66.2 43.0 86.4 62.1 74.0 75.6 STXBP3 UNC-18C ENSG00000116266 "Syntaxin binding protein 3" O00186 1 108746674-108809526 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027225 Approved Approved Nucleoplasm,Cytosol 160000 Nucleoplasm Cytosol "HPA027225: AB_1857627" "unprognostic (3.14e-3)" "unprognostic (4.33e-2)" "unprognostic (7.18e-3)" "unprognostic (4.88e-2)" "unprognostic (6.54e-2)" "unprognostic (9.78e-3)" "unprognostic (2.00e-3)" "unprognostic (1.94e-1)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "unprognostic (6.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.25e-2)" "unprognostic (1.65e-1)" "unprognostic (8.08e-2)" "unprognostic (1.08e-1)" "unprognostic (4.55e-2)" 18.3 18.4 29.8 18.7 42.1 15.2 20.9 21.9 27.1 19.4 20.5 26.3 15.6 18.7 20.3 19.9 18.8 16.0 20.8 14.3 30.4 22.1 30.2 17.8 16.8 18.2 48.0 28.0 16.2 20.5 31.9 18.0 20.3 31.4 18.1 21.9 9.8 17.5 21.3 15.4 19.7 23.8 18.4 56.6 19.8 18.0 11.3 42.5 20.0 27.8 14.6 17.8 20.2 18.3 5.9 8.3 26.2 11.6 8.7 10.2 5.9 21.9 8.7 15.0 7.9 18.3 17.8 21.2 20.4 18.9 13.8 14.1 8.0 8.9 19.5 13.9 16.5 13.2 10.1 12.0 19.4 21.7 14.0 16.1 11.9 10.4 14.5 25.1 27.7 13.8 17.1 15.4 16.9 17.0 11.9 19.3 19.1 14.9 15.8 20.2 16.0 13.8 13.3 21.9 10.7 22.4 18.4 9.0 8.3 25.1 24.3 29.7 9.7 23.9 19.1 18.1 10.6 25.0 17.5 12.9 11.2 16.2 32.5 19.3 27.4 26.2 8.8 20.8 7.8 10.6 9.9 5.9 9.2 7.8 8.3 5.4 7.9 7.5 24.3 8.7 11.6 3.9 10.2 5.9 29.8 42.1 21.9 27.1 30.4 22.1 48.0 28.0 31.4 42.5 STXBP4 "MGC50337, Synip" ENSG00000166263 "Syntaxin binding protein 4" Q6ZWJ1 17 54968727-55173632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 36.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007760, HPA022138, HPA022888, HPA024227" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "CAB007760: AB_562350, HPA022138: AB_1857628, HPA022888: AB_1857629, HPA024227: AB_1857630" "unprognostic (5.89e-2)" "unprognostic (2.50e-2)" "unprognostic (1.30e-3)" "unprognostic (9.27e-2)" "unprognostic (1.03e-3)" "unprognostic (1.48e-1)" "unprognostic (5.00e-5)" "unprognostic (4.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-2)" "unprognostic (3.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" 7.7 6.4 5.5 4.3 6.0 3.4 5.2 10.6 4.7 9.9 6.4 4.2 7.5 6.3 12.0 7.2 5.1 7.3 6.6 5.9 6.7 4.7 14.5 3.8 8.0 3.2 4.2 4.5 9.9 5.4 19.3 36.3 4.7 6.8 9.5 4.6 7.6 4.5 9.4 4.0 3.7 5.1 13.2 8.6 5.0 5.5 5.6 5.1 7.2 7.9 2.7 3.5 9.6 8.2 3.2 2.9 4.0 1.2 5.1 2.9 0.7 5.4 8.2 7.5 6.7 6.4 6.3 3.1 4.3 4.1 5.6 5.5 4.8 3.0 3.7 9.1 4.2 3.3 9.7 4.3 10.3 5.6 5.5 4.9 5.6 9.8 2.7 3.0 1.5 7.2 1.3 8.0 1.9 5.5 7.8 3.0 6.6 2.4 10.0 1.9 5.4 5.9 4.3 8.8 2.2 9.9 3.3 7.3 5.5 6.6 1.1 3.6 9.6 2.1 4.3 7.8 6.2 4.8 4.5 2.6 2.5 6.4 5.1 4.0 4.7 4.0 1.1 0.1 2.6 0.8 2.9 2.1 2.3 1.7 1.4 3.2 2.1 2.7 0.3 5.1 1.2 2.9 2.1 0.7 5.5 6.0 10.6 4.7 6.7 4.7 4.2 4.5 6.8 5.1 SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 82.7" "Cell line enhanced" "Detected in many" "HaCaT: 13.2;PC-3: 14.9;SK-BR-3: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 9.4;naive B-cell: 4.4" "Lineage enriched" "Detected in single" 29 "B-cells: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles Vesicles "HPA053057: " "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favourable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" 17.6 19.7 18.2 2.5 25.5 0.8 13.3 36.8 31.3 7.7 8.7 4.0 11.5 7.1 3.4 7.9 4.1 12.8 6.9 2.6 15.2 23.0 3.3 26.6 5.2 3.1 13.5 17.9 5.5 82.7 1.6 12.4 2.1 14.7 5.1 12.5 3.5 12.6 10.0 2.5 5.3 7.4 5.1 7.2 1.2 8.7 1.7 5.1 0.3 7.6 1.1 5.1 2.9 3.8 9.4 0.1 0.0 0.0 0.0 0.3 0.1 5.1 2.6 2.1 0.0 0.3 0.3 1.4 1.8 0.0 0.0 0.0 4.6 3.1 0.4 0.3 1.4 13.2 0.4 3.5 0.0 0.0 7.1 0.0 7.8 4.6 3.4 0.0 0.0 1.2 4.5 0.0 4.3 1.9 0.2 0.9 2.0 0.1 0.1 0.0 0.4 14.9 0.0 0.0 0.0 5.7 1.2 10.0 1.1 4.7 30.4 1.0 3.8 0.2 2.7 0.1 1.1 0.0 0.8 0.8 0.0 0.3 6.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 9.4 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 18.2 25.5 36.8 31.3 15.2 23.0 13.5 17.9 14.7 5.1 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 61.8;skin 1: 41.6;urinary bladder: 31.4" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.1;hTCEpi: 43.2;T-47d: 11.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052700 Uncertain "HPA052700: " "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.1 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.7 0.9 0.0 6.8 0.7 0.1 7.3 19.9 0.6 61.8 0.1 0.1 0.0 0.5 0.3 2.3 0.0 0.0 0.0 0.1 7.8 0.0 0.1 5.7 0.0 5.6 0.1 0.3 11.8 4.2 0.1 41.6 3.6 6.3 0.1 0.1 3.1 0.1 0.0 0.0 0.1 19.4 13.3 31.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 27.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.2 0.0 5.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.8 0.0 0.2 0.0 2.3 0.0 11.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: " "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavourable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favourable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favourable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 10.4 13.6 15.8 8.8 26.8 13.6 11.4 32.1 28.3 12.7 10.8 22.6 7.9 9.1 14.6 12.3 10.9 12.4 9.7 17.6 13.0 12.1 13.1 9.4 11.6 10.2 12.5 15.1 21.2 12.1 15.9 19.5 15.8 21.1 11.8 12.6 13.1 11.6 10.4 20.0 13.8 11.2 14.2 12.4 13.7 10.6 36.2 14.9 10.5 16.2 8.6 14.2 10.9 11.1 2.8 3.1 4.8 7.0 4.9 7.1 2.6 6.1 7.3 10.0 8.2 10.3 9.8 18.8 8.3 13.4 8.7 8.6 12.4 7.2 14.4 3.6 15.8 16.0 11.7 8.4 8.9 6.9 6.2 4.6 14.5 10.1 12.3 6.7 6.2 10.5 6.4 11.1 13.6 10.0 8.0 7.9 9.9 11.4 6.0 5.8 13.7 6.1 7.3 18.9 8.1 3.9 8.1 5.0 7.7 9.7 6.1 4.8 11.0 4.0 10.3 14.3 8.6 8.5 5.6 4.4 9.8 14.0 8.1 4.0 6.3 4.1 4.4 4.8 6.5 7.0 7.1 1.9 3.6 5.7 3.1 2.8 5.9 5.3 1.7 4.9 3.2 1.8 5.7 2.6 15.8 26.8 32.1 28.3 13.0 12.1 12.5 15.1 21.1 14.9 TUSC5 "BEC-1, IFITMD3, LOST1" ENSG00000184811 "Tumor suppressor candidate 5" Q8IXB3 17 1279663-1300987 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "adipose tissue: 79.1;breast: 63.0" "Cell line enriched" "Detected in single" 262 "ASC diff: 26.1" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA050825 Approved "HPA050825: " "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 79.1 0.9 0.0 2.1 0.0 0.1 63.0 0.0 0.1 0.2 4.1 0.0 0.0 0.1 0.1 0.9 0.2 0.2 3.4 5.2 0.0 0.0 0.4 0.1 0.1 2.2 0.0 0.0 0.2 0.5 0.1 0.0 0.1 0.0 0.1 0.2 0.0 2.5 1.4 4.4 0.8 1.1 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.6 2.7 0.1 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5365009-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 14.9;pancreas: 10.6;pituitary gland: 5.6;stomach 1: 4.6" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 5.4" "Group enriched" "Detected in many" 5 "lung cancer: 5.1;pancreatic cancer: 15.4;stomach cancer: 3.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 5.9" "Region enriched" "Detected in single" 7 "hypothalamus: 4.7" HPA038281 Uncertain "Secreted to blood" "HPA038281: AB_10672408" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-3)" "unprognostic (8.42e-2)" "unprognostic (3.55e-2)" "unprognostic (2.91e-2)" 0.1 0.9 0.1 0.1 0.4 0.0 0.1 0.4 0.4 0.1 14.4 0.1 0.1 11.6 0.1 0.1 0.1 1.2 1.2 0.1 0.1 1.7 0.8 0.1 1.3 0.1 0.1 0.5 0.1 10.6 0.0 5.6 0.1 1.6 0.2 3.1 0.3 0.1 0.1 0.1 0.0 14.9 0.1 0.5 0.1 4.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 5.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.4 0.1 1.7 0.1 0.5 1.6 0.1 UCP2 "BMIQ4, SLC25A8" ENSG00000175567 "Uncoupling protein 2" P55851 11 73974667-73983307 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 219.1;lymphoid tissue: 144.8" "Cell line enhanced" "Detected in many" "Daudi: 66.9;SK-BR-3: 86.1;U-698: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025583, HPA075202" Approved Supported Mitochondria Mitochondria "CAB025583: , HPA075202: " "unprognostic (1.13e-1)" "prognostic favourable (4.65e-5)" "unprognostic (8.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-3)" "unprognostic (2.07e-1)" "unprognostic (4.59e-2)" "unprognostic (1.13e-3)" "unprognostic (1.37e-1)" "prognostic unfavourable (7.80e-6)" "unprognostic (3.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.77e-3)" "unprognostic (3.88e-3)" 19.8 9.8 5.3 40.4 9.5 24.5 15.9 1.1 4.9 8.1 7.7 10.2 20.3 11.4 4.2 12.0 4.5 37.9 13.1 11.5 4.4 5.5 12.8 10.6 20.2 85.6 7.8 2.4 7.2 4.7 1.2 6.2 8.7 6.5 6.5 8.9 14.2 17.4 17.2 45.3 4.3 24.7 6.4 9.0 91.1 12.3 5.5 5.9 144.8 17.9 19.3 55.7 19.4 2.9 141.6 219.1 101.8 135.3 119.8 180.2 172.1 0.1 14.1 3.2 9.6 1.8 0.0 2.4 2.3 1.6 9.7 2.8 24.7 12.0 66.9 33.5 3.6 0.6 2.3 0.0 4.5 16.9 0.8 39.0 5.9 5.1 5.8 20.5 16.4 2.1 0.0 9.1 0.0 1.2 17.9 27.3 1.9 24.1 21.2 11.1 2.6 2.8 19.6 22.3 37.9 27.0 39.9 4.9 6.0 12.6 86.1 4.8 25.4 18.3 1.8 0.0 12.4 2.8 4.6 9.4 4.4 55.7 1.7 8.1 0.1 45.7 81.5 101.8 112.6 135.3 69.9 141.6 92.3 95.0 88.4 134.2 86.9 91.1 11.4 119.8 111.3 219.1 180.2 172.1 5.3 9.5 1.1 4.9 4.4 5.5 7.8 2.4 6.5 5.9 UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" Mitochondria "Nuclear bodies" "HPA039111: " "unprognostic (3.58e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-3)" "unprognostic (2.43e-2)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (7.43e-2)" "unprognostic (5.77e-2)" "unprognostic (3.88e-1)" "unprognostic (1.07e-1)" 13.4 22.9 26.1 13.3 31.4 14.6 17.7 15.0 22.9 12.4 15.8 12.0 12.3 12.8 17.4 23.4 15.2 10.9 9.2 71.0 19.2 23.0 18.3 23.4 8.9 12.3 22.8 22.6 11.5 25.3 7.9 24.5 14.4 20.6 15.7 17.2 18.9 19.6 14.3 76.4 12.2 10.4 20.0 20.0 12.9 15.9 30.9 18.3 12.3 19.0 22.0 14.9 10.9 11.0 39.7 38.9 7.2 39.6 21.9 31.5 34.8 42.4 30.6 34.3 29.7 28.5 28.8 27.0 24.3 24.4 33.8 33.5 49.1 18.0 17.1 39.2 29.2 22.9 23.3 33.9 30.1 21.8 38.3 33.5 20.3 67.8 46.8 31.2 27.5 29.3 54.6 27.1 43.9 25.1 35.6 35.5 39.7 45.7 30.2 64.9 20.8 34.9 21.9 28.1 58.0 23.9 40.4 59.0 20.9 26.8 41.0 33.5 36.0 79.5 23.2 38.9 33.0 25.0 49.9 27.4 38.0 28.9 11.7 47.3 44.8 7.2 27.0 5.2 24.0 39.6 29.1 39.7 30.3 27.4 31.9 32.8 31.5 28.4 2.6 21.9 32.7 38.9 31.1 34.8 26.1 31.4 15.0 22.9 19.2 23.0 22.8 22.6 20.6 18.3 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165593 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 59.4;pituitary gland: 30.4" "Cell line enhanced" "Detected in some" "SH-SY5Y: 35.9;SK-MEL-30: 96.8;U-2 OS: 17.6;WM-115: 29.0" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" 1273770 2800000 "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavourable (4.25e-4)" "prognostic unfavourable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 3.8 3.1 10.9 2.3 25.2 1.3 1.1 1.3 59.4 1.1 1.5 1.3 0.0 1.3 2.2 1.1 1.1 1.1 1.2 1.2 12.2 51.0 1.4 1.1 1.1 1.1 3.9 22.8 1.1 6.2 1.1 30.4 1.2 41.2 1.2 1.2 0.5 1.1 1.1 1.1 1.4 1.3 1.5 6.6 1.2 3.6 1.4 0.5 0.0 1.2 0.0 1.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.2 1.9 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.7 0.4 0.0 4.6 0.0 0.4 3.6 0.4 0.1 0.0 0.0 0.0 0.0 2.9 35.9 0.0 0.1 96.8 0.0 0.0 0.0 0.0 17.6 0.0 0.4 0.0 0.1 0.9 2.8 0.0 29.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 25.2 1.3 59.4 12.2 51.0 3.9 22.8 41.2 0.5 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 165.7" "Group enriched" "Detected in some" 5 "HaCaT: 43.2;Hep G2: 43.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol Cytosol "HPA053808: " "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 1.4 13.6 36.5 1.7 48.8 1.2 3.9 91.6 165.7 1.8 3.0 3.3 0.0 1.3 1.7 1.2 18.0 1.9 1.3 17.5 34.8 27.9 2.0 10.5 2.4 1.2 19.9 66.1 2.8 1.7 1.2 0.2 3.4 64.0 3.0 3.6 0.1 3.2 1.5 1.7 5.2 1.3 1.6 7.1 1.3 1.7 1.5 1.4 0.0 1.5 3.1 4.1 2.3 3.4 0.1 0.7 0.2 0.1 0.1 0.5 0.1 0.2 0.0 0.5 7.8 0.9 1.3 0.0 0.0 0.0 0.0 0.2 0.1 4.7 0.0 0.0 0.0 43.2 0.3 1.5 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.1 0.3 2.3 0.0 1.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.1 3.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.5 0.1 0.2 0.1 0.1 0.7 0.0 0.1 36.5 48.8 91.6 138.6 34.8 27.9 19.9 66.1 64.0 1.4 ARRB1 ARR1 ENSG00000137486 "Arrestin beta 1" P49407 11 75264182-75351705 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 49.5;RH-30: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 37.5" "Group enriched" "Detected in many" 5 "dendritic cells: 12.7;granulocytes: 14.7;monocytes: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003763, HPA049318, HPA070249" Approved Supported Nucleoplasm 2100000 Nucleoplasm "CAB003763: AB_562248, HPA049318: , HPA070249: " "unprognostic (3.40e-1)" "unprognostic (8.37e-2)" "unprognostic (1.63e-1)" "unprognostic (1.88e-1)" "unprognostic (2.35e-1)" "unprognostic (3.27e-3)" "unprognostic (1.33e-2)" "unprognostic (1.15e-2)" "unprognostic (1.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (9.35e-2)" "unprognostic (2.34e-2)" "unprognostic (2.29e-1)" "unprognostic (7.10e-2)" "unprognostic (3.90e-1)" "unprognostic (1.26e-1)" 20.9 5.4 27.7 14.7 31.7 9.6 15.9 24.4 36.7 6.9 17.8 11.2 2.0 15.4 7.6 4.5 13.8 12.1 9.2 12.2 25.0 16.0 9.1 7.4 37.3 9.7 19.1 25.7 12.5 28.8 1.8 3.3 17.7 21.8 12.0 16.9 10.1 8.5 7.5 7.2 11.6 18.5 15.9 6.4 26.5 23.1 3.1 19.0 3.8 6.4 3.9 7.2 13.2 7.9 0.1 12.7 14.7 37.5 3.9 3.6 10.9 1.5 7.0 7.3 3.5 6.4 5.5 15.0 1.5 5.1 1.9 1.3 10.2 7.1 0.6 17.9 1.4 0.3 2.9 0.0 0.7 0.0 1.6 49.5 0.9 6.1 1.6 1.4 19.1 2.7 0.3 3.2 0.0 21.4 24.0 0.0 3.6 4.0 0.9 16.7 5.3 2.1 5.4 34.5 1.9 7.6 6.1 3.8 4.0 2.6 18.4 4.4 13.5 8.0 17.8 1.4 1.9 5.7 0.1 0.0 0.0 0.0 1.0 23.1 1.7 8.3 19.8 13.0 3.6 31.3 1.3 0.1 1.7 2.0 12.7 0.0 1.5 2.1 14.7 3.9 37.5 0.2 1.5 10.9 27.7 31.7 24.4 36.7 25.0 16.0 19.1 25.7 21.8 19.0 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402452-42423517 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 110.3;TIME: 91.5;U-138 MG: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" 29000 "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: " "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavourable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavourable (5.87e-4)" 105.6 12.7 4.7 26.4 5.4 0.7 111.2 4.5 7.6 68.6 52.0 15.3 31.9 7.1 65.6 45.6 60.3 37.1 74.0 37.3 6.4 4.6 12.1 6.6 47.0 15.6 7.7 6.1 57.8 6.8 7.5 6.9 47.7 13.6 51.8 12.4 34.0 17.4 53.8 45.4 28.6 18.6 115.4 14.7 23.9 27.0 24.3 5.2 3.3 30.4 47.9 12.6 80.6 57.9 0.9 0.6 2.7 0.5 0.7 1.2 0.2 30.6 26.3 0.5 7.0 35.6 42.9 0.7 110.3 48.1 44.1 35.0 13.2 2.0 0.0 22.1 78.8 50.7 4.7 33.0 36.1 0.1 0.9 13.4 16.1 6.4 22.5 0.0 0.1 29.4 12.2 34.6 11.9 59.4 9.1 0.1 18.8 0.4 0.7 0.1 2.6 0.1 0.0 17.6 0.0 18.8 0.1 0.0 0.2 37.0 0.6 8.8 3.0 0.2 91.5 93.8 44.1 33.5 40.0 0.0 0.0 0.1 27.8 0.0 10.5 2.7 0.5 0.3 0.5 0.4 0.3 0.3 1.2 0.3 0.2 0.9 0.6 0.3 2.3 0.7 0.4 0.6 0.3 0.2 4.7 5.4 4.5 7.6 6.4 4.6 7.7 6.1 13.6 5.2 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498320 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 203.7" "Cell line enhanced" "Detected in many" "Hep G2: 49.9;SCLC-21H: 70.2;SiHa: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" 470000 Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: " "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavourable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavourable (2.12e-4)" 27.7 33.8 123.1 4.4 135.5 0.9 21.5 82.9 203.7 10.7 9.6 31.6 5.3 5.0 13.3 94.3 16.4 15.7 14.0 19.6 116.9 56.3 12.0 6.3 11.0 7.6 56.9 70.7 23.4 35.5 33.9 40.0 2.2 53.0 66.5 8.8 13.2 12.0 20.1 11.0 5.5 6.2 18.5 40.5 2.8 19.2 30.4 53.3 0.9 40.7 4.3 7.7 6.3 9.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.3 9.0 1.7 7.2 0.8 0.4 0.0 3.6 1.3 2.9 0.0 0.0 0.0 2.6 0.0 0.2 3.4 0.7 0.8 0.0 13.2 0.0 3.7 49.9 0.5 0.0 0.0 17.6 3.7 0.0 0.0 0.0 0.0 0.3 1.8 2.5 0.0 0.4 5.7 2.0 0.0 0.0 0.1 0.1 0.5 70.2 23.2 103.0 12.9 0.0 7.7 0.3 0.0 2.8 7.2 0.2 0.2 3.9 0.0 0.3 2.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 123.1 135.5 82.9 82.2 116.9 56.3 56.9 70.7 53.0 53.3 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19373545 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favourable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 31.5 14.0 7.4 11.2 9.4 5.8 17.8 17.7 10.4 18.8 17.9 7.3 17.5 17.4 15.0 12.7 15.8 12.5 9.9 13.7 8.0 5.7 10.2 10.1 16.3 7.2 9.1 6.7 16.3 16.0 16.9 18.2 14.6 8.4 14.9 14.5 10.4 16.9 12.2 11.5 20.5 18.4 19.1 8.9 9.8 13.8 9.0 9.6 14.3 12.9 8.3 11.0 22.3 17.7 3.0 4.0 8.5 2.1 8.1 10.2 3.4 11.6 10.9 7.9 10.2 17.3 21.0 14.4 6.7 10.1 7.1 9.5 5.4 7.7 4.9 5.6 8.8 6.3 9.2 5.6 8.7 32.5 5.2 22.6 12.6 6.3 8.6 5.2 12.9 8.2 12.8 6.2 10.6 13.2 6.1 5.7 9.0 4.4 9.2 11.6 5.9 5.5 8.3 4.6 7.1 18.7 22.4 8.0 5.9 6.0 13.5 4.7 8.3 7.1 12.3 6.3 3.5 6.9 6.9 3.9 9.4 2.6 5.2 5.1 3.5 8.5 2.1 2.5 7.8 1.1 10.2 2.5 6.7 7.8 4.0 3.0 6.1 7.3 1.1 8.1 1.1 4.0 4.8 3.4 7.4 9.4 17.7 10.4 8.0 5.7 9.1 6.7 8.4 9.6 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423777-42721878 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adipose tissue: 44.4;breast: 31.5;liver: 82.4;skeletal muscle: 23.4" "Group enriched" "Detected in some" 5 "HSkMC: 13.3;T-47d: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" 2200000 21000000 "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: , HPA057705: " "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favourable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 44.4 2.8 0.7 5.4 1.3 0.3 31.5 0.4 1.4 4.0 6.9 0.5 1.7 0.6 5.7 3.9 2.4 2.5 3.9 6.0 1.3 1.6 5.3 82.4 2.3 2.2 1.2 1.4 5.0 1.3 3.6 2.0 4.0 2.0 8.7 2.5 2.4 2.3 7.4 23.4 3.0 2.4 5.2 1.0 2.6 3.5 1.6 0.2 0.1 2.9 4.3 0.5 3.8 8.4 0.6 0.3 1.8 0.5 0.4 0.3 0.1 0.0 0.0 0.3 3.0 2.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.5 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 13.3 4.3 0.0 0.6 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.1 33.9 0.0 1.8 3.0 1.3 1.6 0.3 0.3 0.0 0.0 0.3 0.0 1.5 1.8 0.3 0.4 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.6 0.2 0.3 1.7 0.4 0.5 0.3 0.2 0.1 0.7 1.3 0.4 1.4 1.3 1.6 1.2 1.4 2.0 0.2 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease mutation, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 303.3;thyroid gland: 304.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favourable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 56.2 79.0 84.2 34.4 44.5 42.1 87.4 86.0 107.4 43.2 42.3 25.4 27.0 33.2 37.2 44.7 41.0 43.6 34.4 106.0 71.0 144.0 39.6 35.3 46.6 44.6 75.8 64.7 43.6 118.1 120.9 303.3 49.8 85.6 36.3 31.5 42.7 171.6 31.1 172.9 26.3 34.9 40.5 61.4 36.9 42.4 18.2 27.4 56.0 304.5 80.6 41.0 37.3 44.6 27.3 41.5 29.9 36.2 25.3 24.2 24.6 9.6 32.5 54.8 25.5 93.1 42.6 49.2 55.8 51.0 63.9 45.8 94.7 50.1 31.7 86.9 72.5 41.8 50.2 74.3 43.3 20.9 30.2 35.2 49.4 62.0 43.1 20.4 22.2 50.7 37.8 31.0 41.7 48.3 30.9 43.3 42.0 132.2 104.3 50.1 17.4 34.4 64.2 48.0 55.9 51.2 38.2 68.0 155.7 77.6 77.0 62.2 58.9 56.1 53.1 84.8 76.2 30.5 52.5 75.9 49.0 66.9 37.2 10.0 43.2 29.9 24.8 29.5 20.7 35.7 22.1 26.7 22.0 22.2 37.8 27.3 21.3 24.2 29.1 25.3 36.2 41.5 23.3 24.6 84.2 44.5 86.0 107.4 71.0 144.0 75.8 64.7 85.6 27.4 GPR119 "GPCR2, hGPCR2" ENSG00000147262 "G protein-coupled receptor 119" Q8TDV5 X 130384440-130385447 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.5;pancreas: 8.0" "Group enriched" "Detected in some" 20 "CACO-2: 2.7;Hep G2: 5.8" "Cancer enriched" "Detected in single" 11 "pancreatic cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "prognostic favourable (6.93e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686432-37745247 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 34.7;kidney: 66.2;pancreas: 18.6" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 52.0" "Cancer enhanced" "Detected in many" "renal cancer: 32.5" "Cell type enriched" "Detected in single" 5 "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 5 "B-cells: 1.0" "Group enriched" "Detected in some" 5 "basal ganglia: 0.7;hypothalamus: 2.3" "Low region specificity" "Detected in some" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB068192: , HPA002083: AB_1080232" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (5.29e-3)" "unprognostic (5.29e-2)" "unprognostic (3.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "prognostic favourable (6.00e-4)" "unprognostic (7.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.49e-2)" "prognostic favourable (2.51e-6)" 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.1 4.5 0.0 4.8 3.8 0.9 7.8 0.0 2.8 34.7 0.0 0.0 66.2 7.7 3.7 0.0 0.0 0.0 0.8 18.6 1.6 0.0 0.6 0.0 1.6 3.4 0.0 0.0 3.8 0.0 0.0 5.5 0.3 0.0 0.0 3.7 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.8 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 52.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355700-44434596 "Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 65.5;kidney: 30.5;liver: 57.3" "Group enriched" "Detected in some" 9 "CACO-2: 51.6;Hep G2: 37.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm Nucleoplasm "CAB019417: AB_2295208, HPA004712: AB_1079075" "unprognostic (2.47e-1)" "unprognostic (3.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-2)" "unprognostic (4.79e-3)" "unprognostic (2.59e-2)" "unprognostic (3.77e-2)" "unprognostic (2.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (8.40e-3)" "unprognostic (2.12e-1)" "unprognostic (2.70e-2)" 0.2 0.2 0.2 13.4 0.2 0.0 0.2 0.2 0.3 0.2 54.0 0.2 0.1 33.0 0.2 6.2 0.2 0.4 15.7 0.2 0.2 0.2 30.5 57.3 0.3 0.1 0.2 0.1 0.3 22.7 0.0 0.2 0.1 0.2 0.2 14.4 0.2 0.2 0.1 0.2 0.2 65.5 0.3 0.2 0.2 7.1 0.4 0.1 0.1 0.2 0.1 0.1 0.2 0.4 0.4 0.6 1.2 0.8 0.8 0.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.6 2.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.4 0.4 0.4 0.7 0.8 0.8 0.6 0.3 0.0 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.1 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974164-38988662 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "placenta: 55.2" "Cell line enriched" "Detected in single" 134 "BEWO: 71.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in some" "hippocampal formation: 2.3" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" "HPA045402: " "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 2.6 1.1 0.2 0.3 0.2 3.4 0.9 0.2 0.4 1.2 0.5 0.2 1.9 0.0 2.3 0.5 0.5 0.1 0.2 0.2 0.2 0.0 0.2 0.2 4.3 1.0 0.2 0.2 0.4 0.3 0.4 0.5 55.2 0.4 0.5 0.3 1.8 0.8 0.5 0.6 0.4 0.6 0.3 1.8 2.5 0.1 0.4 0.2 0.2 0.6 0.2 0.8 0.5 0.9 3.1 2.2 2.5 1.0 1.0 1.7 0.0 0.1 0.1 0.1 0.1 0.3 0.2 71.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.1 0.5 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.1 1.5 0.8 2.3 1.4 0.7 1.7 1.5 1.3 1.2 0.6 3.1 1.3 1.4 2.5 1.0 1.0 2.2 1.4 0.0 0.2 0.2 0.2 0.4 0.2 0.0 0.2 0.2 0.4 0.2 ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 58.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 16.2;MCF7: 15.2;RT4: 17.8;SCLC-21H: 24.9;SH-SY5Y: 41.0;SK-BR-3: 19.5;T-47d: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "T-reg: 20.8" "Lineage enriched" "Detected in many" 8 "T-cells: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: " "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favourable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" 8.9 6.1 12.6 4.2 15.3 11.7 13.0 19.4 24.2 10.7 13.2 2.5 8.7 7.7 5.5 8.5 5.8 8.1 10.4 25.7 7.7 7.8 9.1 5.3 9.2 6.9 4.8 12.4 1.6 58.6 13.2 13.5 4.6 10.5 13.7 14.3 2.5 21.2 8.3 2.8 7.0 10.4 3.7 2.8 7.6 17.9 16.0 3.2 0.8 8.1 4.1 5.5 9.6 4.1 0.3 1.7 2.4 1.6 0.7 20.8 1.1 0.0 0.3 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.3 16.2 0.1 1.6 0.0 0.0 0.3 0.7 0.0 0.0 2.4 3.4 0.3 0.0 0.1 2.8 0.5 0.0 1.1 0.0 0.0 11.8 9.5 0.0 0.0 15.2 0.1 0.0 3.7 0.1 0.0 0.0 7.0 6.9 17.8 24.9 41.0 0.0 19.5 0.2 15.8 5.1 6.9 0.0 0.3 0.0 0.3 5.1 2.4 0.0 0.0 2.2 3.4 0.5 1.6 0.1 0.2 0.5 0.4 0.2 3.9 0.3 1.7 0.3 0.2 0.1 2.4 0.7 0.2 0.4 20.8 1.1 12.6 15.3 19.4 24.2 7.7 7.8 4.8 12.4 10.5 3.2 IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229752-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 51.5;tongue: 29.7" "Group enriched" "Detected in some" 7 "HaCaT: 6.2;RT4: 22.8;SK-BR-3: 7.8" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014001 Uncertain "Secreted in other tissues" "HPA014001: " "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.1 14.7 0.1 0.0 0.0 0.1 0.3 0.1 51.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 11.0 0.1 0.1 1.8 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.9 0.1 29.7 14.4 0.4 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.2 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.1 7.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "skin 1: 26.8;tongue: 24.8" "Cell line enriched" "Detected in single" 42 "CACO-2: 42.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 24 "memory CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 24 "T-cells: 2.4" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" Nucleoplasm "Plasma membrane" "HPA059137: " "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" 1.5 0.0 0.4 0.1 0.1 0.0 1.8 0.1 0.4 0.3 0.3 0.1 0.1 0.0 0.1 0.5 1.0 0.0 0.1 1.1 0.1 0.1 0.1 0.1 0.8 1.2 0.4 0.1 0.1 0.1 3.4 0.1 1.6 0.9 0.1 0.7 0.1 0.5 0.1 0.1 26.8 0.1 0.1 0.3 0.1 0.0 2.4 0.1 0.4 0.1 24.8 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 42.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.1 0.1 0.4 0.1 0.9 0.1 IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120071-46124674 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 22.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.1;CACO-2: 2.1;hTEC/SVTERT24-B: 2.8;U-2 OS: 3.0;U-87 MG: 5.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" HPA062776 Uncertain "Secreted in other tissues" "HPA062776: " "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 2.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.9 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 22.4 0.1 0.1 0.1 0.1 0.0 2.9 0.1 1.9 0.1 2.7 0.1 0.1 0.1 1.5 0.2 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.6 0.5 2.1 0.3 0.0 0.4 0.0 0.1 0.0 0.0 1.4 0.3 0.0 0.0 0.6 0.3 0.0 0.0 0.1 1.1 0.5 2.8 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.1 0.6 0.0 0.2 5.4 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.6 0.6 0.1 0.2 0.2 1.5 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 NOV "CCN3, IGFBP9" ENSG00000136999 "Nephroblastoma overexpressed" P48745 8 119416306-119424353 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 236.7" "Group enriched" "Detected in many" 5 "BJ hTERT+: 43.0;U-2197: 44.5" "Cancer enhanced" "Detected in all" "melanoma: 62.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 113 "eosinophil: 28.1;neutrophil: 14.0" "Lineage enriched" "Detected in single" 151 "granulocytes: 28.1" "Group enriched" "Detected in many" 7 "amygdala: 134.6;basal ganglia: 51.6;cerebral cortex: 101.0;hippocampal formation: 166.1" "Low region specificity" "Detected in many" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" 269030000 2900000 Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 6.3 236.7 2.2 1.4 7.9 1.0 5.6 3.1 12.3 5.0 2.0 3.6 3.6 1.5 5.8 2.9 1.9 3.0 2.0 5.7 3.5 1.9 4.9 0.9 2.9 1.1 2.1 15.1 1.8 2.7 2.1 13.4 0.8 7.4 5.6 2.2 1.2 1.2 5.0 1.6 3.6 1.5 2.5 2.5 1.0 1.6 2.6 0.0 0.0 6.9 4.8 1.1 3.3 2.5 0.0 0.1 28.1 0.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 3.9 1.0 0.0 5.7 43.0 5.2 3.0 0.0 0.1 0.0 4.5 7.2 3.6 0.2 0.0 1.7 0.0 0.1 0.0 3.3 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 8.6 0.0 0.0 0.0 5.5 0.0 1.3 0.0 2.1 0.0 8.0 0.0 0.0 0.0 3.7 5.7 44.5 1.1 0.0 0.0 0.0 5.9 1.8 4.3 0.0 0.1 28.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 2.2 7.9 3.1 12.3 3.5 1.9 2.1 15.1 7.4 0.0 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153804-116402322 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 86 "placenta: 484.6" "Cell line enhanced" "Detected in some" "ASC diff: 19.0;ASC TERT1: 14.5;HSkMC: 52.2;U-138 MG: 13.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "midbrain: 10.4;olfactory region: 4.1;pons and medulla: 8.3;thalamus: 4.8" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" 41000 "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.8 2.3 0.5 1.0 0.5 0.0 0.8 0.4 0.6 3.6 2.4 0.6 1.0 0.1 3.5 1.0 3.6 2.0 1.1 3.7 0.4 0.0 4.3 0.5 2.4 0.7 0.4 0.4 1.4 0.7 5.6 0.7 484.6 0.7 1.4 0.9 0.9 0.5 1.2 0.5 1.1 0.9 2.4 0.6 0.6 1.0 0.8 0.5 0.4 1.3 1.0 1.0 2.3 3.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 8.3 0.0 19.0 14.5 0.0 4.4 7.8 1.2 2.1 0.0 0.0 0.0 0.0 3.1 0.6 0.0 0.0 5.9 0.0 0.0 0.9 4.5 0.0 9.2 0.0 0.0 52.2 0.0 6.1 0.7 0.0 0.2 0.0 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 10.5 13.6 0.7 0.3 0.5 0.0 0.0 0.0 9.7 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.6 0.4 0.0 0.4 0.4 0.7 0.5 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell line enriched" "Detected in some" 7 "ASC diff: 104.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056731 Approved "HPA056731: " "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 7.8 0.3 2.0 104.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.3 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.0 0.5 0.1 0.5 0.0 0.6 1.6 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: " "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavourable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.4 4.9 5.7 5.1 13.1 9.0 5.1 5.6 12.5 6.6 9.3 5.0 12.9 12.3 3.8 9.2 6.3 7.5 6.4 10.5 6.2 2.1 4.1 12.8 6.1 14.0 13.8 7.1 6.1 17.9 8.3 10.8 9.3 3.1 33.6 6.0 8.0 7.7 25.1 2.1 0.0 12.0 3.0 9.1 10.3 6.0 2.0 9.2 7.5 3.5 9.4 9.9 20.0 8.1 21.9 5.1 8.5 4.5 11.1 14.3 14.1 6.8 13.1 1.3 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034107-26137454 "Predicted intracellular proteins" "Protein transport, Transport" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved 14000000 "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavourable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavourable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 17.8 21.8 24.1 15.9 21.0 6.0 20.4 16.0 23.2 23.0 22.2 22.6 11.9 15.6 16.9 16.4 82.0 15.8 17.4 18.6 22.8 22.3 22.2 18.4 15.9 22.7 28.7 15.6 16.4 20.9 20.2 13.5 15.6 22.0 17.1 22.9 10.6 24.6 17.4 72.8 26.9 20.2 18.7 34.7 28.0 21.9 13.2 23.9 19.7 21.3 62.6 41.8 21.4 32.7 11.1 22.0 16.8 44.5 15.2 13.7 21.8 36.2 43.3 21.0 17.5 44.5 37.0 20.2 28.5 25.1 23.1 20.6 25.3 27.3 24.7 27.4 31.1 20.0 25.2 27.3 24.8 25.4 17.3 42.6 18.9 42.2 41.5 35.0 24.3 30.2 45.2 28.1 33.5 29.1 35.0 25.2 31.2 16.1 21.2 27.4 21.3 25.4 20.6 44.1 41.6 46.7 35.4 29.6 27.5 24.0 44.5 29.3 19.5 25.5 35.2 35.9 18.6 24.8 30.5 16.5 25.6 39.8 36.1 42.3 27.3 13.9 23.7 10.5 10.7 42.4 12.9 11.1 12.7 11.4 22.0 9.8 11.0 12.1 16.8 15.2 44.5 7.6 13.7 21.8 24.1 21.0 16.0 23.2 22.8 22.3 28.7 15.6 22.0 23.9 RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 7.7;myeloid DC: 10.7;plasmacytoid DC: 12.0" "Group enriched" "Detected in many" 9 "dendritic cells: 12.0;monocytes: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003996 Approved Supported "Plasma membrane,Cytosol" 4600000 "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" 49.0 40.4 18.1 28.7 30.2 29.7 52.1 13.6 23.5 33.1 33.6 13.7 46.6 17.8 28.5 47.1 43.2 25.0 46.7 36.9 21.9 17.0 61.3 51.5 40.8 36.7 22.9 11.1 39.2 65.6 28.4 11.1 29.0 29.1 41.5 24.5 21.6 47.4 44.4 26.8 25.0 28.7 35.3 31.3 44.8 34.5 24.0 24.7 5.9 54.8 35.0 24.9 41.0 78.4 1.0 12.0 0.9 7.7 0.0 0.7 2.4 17.1 21.1 19.2 20.1 64.4 115.1 6.2 20.9 49.5 18.9 19.3 21.3 14.6 0.0 31.5 24.9 11.8 11.3 19.0 26.3 11.0 8.8 14.3 13.3 11.9 27.0 0.0 10.1 83.7 16.5 32.6 14.5 32.9 3.0 0.0 32.1 35.6 0.0 7.3 30.8 20.2 4.1 24.9 0.0 42.6 18.1 1.2 15.8 27.3 23.7 42.1 38.9 11.4 60.9 34.4 20.4 21.3 22.6 0.1 0.0 0.2 53.6 2.4 52.2 0.0 7.7 0.1 0.0 1.4 0.1 0.8 0.1 0.1 10.7 1.0 0.1 0.7 0.9 0.0 0.2 12.0 0.0 2.4 18.1 30.2 13.6 23.5 21.9 17.0 22.9 11.1 29.1 24.7 SLC25A33 "BMSC-MCP, MGC4399, PNC1" ENSG00000171612 "Solute carrier family 25 member 33" Q9BSK2 1 9539482-9585179 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 6.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049982 Uncertain "HPA049982: " "unprognostic (1.61e-1)" "prognostic favourable (4.86e-4)" "unprognostic (2.94e-2)" "unprognostic (4.80e-2)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.18e-2)" "prognostic favourable (7.02e-4)" "unprognostic (1.88e-3)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (4.55e-3)" "unprognostic (7.27e-2)" "unprognostic (1.19e-1)" "unprognostic (4.25e-2)" "unprognostic (3.77e-2)" 14.6 5.3 11.3 3.8 15.3 11.0 13.0 8.4 20.6 4.1 6.6 6.5 3.5 3.4 4.6 18.9 4.5 3.5 5.6 6.1 9.4 12.2 13.9 15.1 6.1 4.6 15.1 8.7 3.3 8.5 4.5 6.4 2.3 12.6 6.3 5.6 10.5 7.0 3.8 16.8 2.6 3.4 4.1 10.4 3.3 4.7 16.0 7.0 4.2 7.6 2.8 5.1 4.1 2.5 2.0 1.6 6.1 1.1 1.3 1.9 0.4 4.3 2.0 5.8 8.9 4.8 2.7 3.7 4.2 4.0 7.2 6.4 4.5 3.4 12.8 5.2 3.5 1.9 14.6 2.8 9.0 9.8 9.2 12.5 2.9 17.6 10.4 12.4 10.0 3.3 5.0 7.2 3.5 4.2 12.1 6.7 4.0 4.6 7.8 8.5 7.2 4.9 10.6 6.1 8.2 4.6 2.5 10.2 6.6 4.8 14.8 12.5 5.4 9.2 1.8 4.6 6.0 6.1 5.4 7.9 14.7 21.5 3.3 13.9 5.5 6.1 0.9 0.3 1.5 1.1 1.0 2.0 1.1 0.9 1.6 1.0 1.9 1.9 1.3 1.3 1.0 1.5 0.2 0.4 11.3 15.3 8.4 20.6 9.4 12.2 15.1 8.7 12.6 7.0 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996348-171026750 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 77.4;liver: 172.8" "Group enriched" "Detected in some" 68 "CACO-2: 7.1;Hep G2: 23.7" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB010444: AB_641068, HPA028997: " "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favourable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 27.9 0.0 0.0 10.8 0.1 0.2 0.1 0.1 3.8 0.1 0.1 0.1 15.3 172.8 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 77.4 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 23.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 SOCS1 "Cish1, JAB, SOCS-1, SSI-1, TIP3" ENSG00000185338 "Suppressor of cytokine signaling 1" O15524 16 11254405-11256200 "Cancer-related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.3;lymphoid tissue: 58.3" "Cell line enriched" "Detected in some" 5 "HDLM-2: 47.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 15.2" "Cell type enhanced" "Detected in many" "basophil: 12.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010355, HPA074108" Approved Supported "Nucleoplasm,Cytoplasmic bodies" Nucleoplasm "Cytoplasmic bodies" "CAB010355: AB_2193144, HPA074108: " "unprognostic (4.50e-3)" "unprognostic (3.30e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-2)" "unprognostic (1.25e-2)" "prognostic favourable (1.10e-4)" "unprognostic (1.71e-2)" "unprognostic (4.09e-3)" "unprognostic (5.31e-3)" "unprognostic (4.82e-2)" "unprognostic (1.17e-1)" "unprognostic (5.39e-2)" "prognostic unfavourable (1.08e-6)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (6.08e-2)" "unprognostic (1.67e-1)" 10.9 2.8 0.7 19.2 1.5 13.9 37.9 15.2 1.1 15.8 6.3 0.3 2.2 3.3 4.9 7.6 5.6 4.2 11.0 3.6 0.6 1.0 11.1 42.3 9.6 25.8 0.8 0.0 9.3 3.8 0.7 16.8 9.3 2.4 5.3 1.8 3.2 3.7 3.9 2.3 6.0 11.0 6.5 1.1 14.7 6.6 7.1 0.4 58.3 5.1 4.8 14.7 5.4 8.3 4.4 1.3 12.9 0.1 5.5 2.7 0.4 1.2 0.2 0.5 0.1 1.6 0.2 1.8 1.0 7.3 0.4 0.6 0.3 0.2 2.8 2.2 0.4 0.5 0.2 0.1 0.1 47.2 0.3 0.7 0.0 3.8 0.6 0.0 8.7 0.6 0.1 1.0 0.0 0.1 6.3 0.8 0.0 1.1 3.1 1.8 5.3 0.8 0.3 0.3 0.3 0.5 0.2 0.7 0.1 0.2 1.7 0.5 0.0 0.4 0.0 0.6 3.1 0.4 0.6 0.2 0.2 4.4 1.2 0.3 0.6 12.9 0.1 8.8 2.2 0.0 2.0 1.4 2.5 2.7 0.0 4.4 2.7 2.5 0.3 5.5 0.0 1.3 2.6 0.4 0.7 1.5 15.2 0.6 0.6 1.0 0.8 0.0 2.4 0.4 STXBP5L "KIAA1006, LLGL4" ENSG00000145087 "Syntaxin binding protein 5 like" Q9Y2K9 3 120908072-121424761 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.2;ovary: 19.7" "Cell line enhanced" "Detected in some" "AF22: 8.1;HeLa: 5.9;MOLT-4: 7.7;RH-30: 4.0;SCLC-21H: 11.1;SH-SY5Y: 4.9;U-937: 4.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.42e-1)" "unprognostic (9.47e-2)" "unprognostic (6.30e-2)" "unprognostic (2.85e-3)" "unprognostic (1.75e-1)" "unprognostic (2.89e-2)" "unprognostic (7.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" "unprognostic (6.73e-3)" "unprognostic (2.52e-1)" "unprognostic (6.52e-3)" "unprognostic (5.13e-2)" "unprognostic (3.58e-1)" "unprognostic (1.86e-3)" "unprognostic (8.61e-3)" 0.9 4.3 9.1 0.9 15.4 0.8 0.8 55.2 22.6 1.8 1.6 1.3 1.3 1.3 2.6 0.8 1.4 1.1 0.9 0.8 13.9 3.4 0.8 0.8 0.9 0.8 3.1 17.1 19.7 1.2 0.8 12.6 0.9 22.4 5.2 1.2 0.0 0.9 7.4 0.8 0.8 1.4 2.5 2.1 0.8 1.7 4.3 2.5 0.0 16.1 0.0 0.8 1.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 5.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.7 0.0 4.0 0.8 0.0 4.0 0.0 0.0 0.8 11.1 4.9 0.0 0.0 0.1 1.1 2.9 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.0 2.2 4.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 15.4 55.2 22.6 13.9 3.4 3.1 17.1 22.4 2.5 SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719632-16765336 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: AB_1080142, HPA000882: , HPA048047: " "unprognostic (4.66e-2)" "unprognostic (2.99e-2)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (9.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "prognostic favourable (3.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-3)" 17.6 31.3 13.1 12.9 12.3 26.2 16.5 10.2 14.0 17.1 23.8 12.2 16.1 20.6 17.0 13.7 18.5 14.4 20.7 25.7 13.5 13.7 28.7 51.4 17.6 11.4 15.8 11.0 19.9 14.3 22.8 15.9 18.9 18.4 16.2 16.1 10.7 15.9 21.3 22.5 12.6 33.0 12.3 17.3 13.7 16.9 10.1 11.2 15.3 16.2 13.3 15.1 17.9 13.5 12.6 11.1 17.8 15.0 13.8 15.2 9.1 16.0 13.6 9.8 18.3 13.4 15.2 4.5 12.8 9.2 10.8 10.8 12.7 13.4 12.6 18.9 12.5 9.6 11.9 16.8 14.4 8.2 23.9 5.0 14.6 12.1 9.6 8.5 7.8 10.4 8.0 18.6 15.8 14.8 10.8 7.1 14.5 18.9 4.6 9.2 11.4 15.0 5.0 12.4 12.6 15.9 10.6 10.1 12.4 23.9 17.1 12.7 22.6 7.7 11.6 13.9 7.3 28.1 10.4 7.8 6.6 14.6 13.6 4.3 11.3 9.2 10.5 12.7 15.2 11.3 12.3 12.6 13.0 13.9 11.1 10.8 13.1 13.6 17.8 13.8 15.0 9.2 14.4 9.1 13.1 12.3 10.2 14.0 13.5 13.7 15.8 11.0 18.4 11.2 TRIM72 MG53 ENSG00000177238 "Tripartite motif containing 72" Q6ZMU5 16 31214021-31231537 "Predicted intracellular proteins, Transporters" "Exocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 71.6;tongue: 37.7" "Cell line enhanced" "Detected in some" "HL-60: 4.7;LHCN-M2: 8.7;RH-30: 22.6;U-266/70: 14.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 12 "cerebellum: 3.0" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA054909 Enhanced Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA054909: " "unprognostic (2.61e-1)" "unprognostic (3.21e-3)" "unprognostic (5.07e-2)" "unprognostic (9.77e-2)" "unprognostic (3.71e-1)" "unprognostic (3.13e-1)" "unprognostic (2.01e-3)" "unprognostic (2.80e-1)" "unprognostic (6.57e-2)" "unprognostic (4.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.49e-2)" "unprognostic (2.24e-10)" "unprognostic (7.70e-2)" "unprognostic (6.72e-2)" "unprognostic (4.15e-1)" "unprognostic (4.30e-4)" 2.3 0.1 0.1 0.1 0.2 0.3 0.1 3.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 5.5 1.8 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.0 1.0 0.0 71.6 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 1.2 37.7 1.9 0.0 0.0 2.0 1.9 4.9 1.3 2.1 1.3 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.3 0.2 4.7 0.2 1.0 0.1 0.0 0.1 0.0 0.3 0.5 8.7 0.2 0.1 0.4 0.2 0.3 0.3 22.6 3.0 0.0 0.3 1.9 0.2 0.2 0.3 0.1 0.2 1.9 0.1 0.2 0.3 0.2 0.1 14.1 1.2 0.2 0.2 0.3 0.2 4.5 1.3 1.5 1.1 1.2 1.0 1.3 1.0 0.9 0.8 2.0 1.3 1.3 4.9 2.1 1.2 1.9 0.8 0.4 0.1 0.2 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 321.9;salivary gland: 176.0" "Cell line enhanced" "Detected in all" "MCF7: 108.1;SK-BR-3: 101.6;T-47d: 118.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" 15.6 14.3 5.4 20.5 7.2 20.6 75.2 4.2 5.9 39.3 21.9 4.2 73.1 15.6 14.7 26.4 16.9 17.6 22.1 22.9 4.8 5.3 23.1 104.0 23.7 37.3 7.4 3.6 19.0 321.9 10.9 27.4 31.3 8.7 29.3 19.6 8.7 176.0 72.2 15.5 12.6 27.8 10.1 7.3 37.2 39.7 7.4 6.7 30.5 42.7 12.1 47.5 29.2 24.9 10.0 22.1 44.2 7.6 25.0 29.9 9.6 8.6 5.8 8.4 12.9 15.9 17.5 21.3 15.1 25.9 15.1 20.1 9.4 12.1 32.9 7.4 13.9 12.0 15.5 7.4 13.1 14.6 9.8 9.9 5.2 40.1 34.5 18.5 9.5 10.9 44.5 10.0 43.3 12.0 8.8 41.5 9.1 108.1 2.5 17.6 5.8 9.2 18.9 9.2 44.6 13.8 12.0 11.1 10.7 9.1 101.6 39.3 118.2 21.4 6.8 8.7 8.4 9.2 5.3 70.7 49.9 19.7 11.6 23.8 13.0 44.2 7.6 6.1 22.9 4.0 29.9 10.0 16.5 23.6 6.9 8.2 16.4 13.7 0.6 25.0 2.8 22.1 5.5 9.6 5.4 7.2 4.2 5.9 4.8 5.3 7.4 3.6 8.7 6.7 YWHAG PPP1R170 ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326794-76359031 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 117.8;skeletal muscle: 91.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918, HPA061603" Approved Approved Supported Nucleoplasm,Nucleoli,Cytosol 160000000 Cytosol "Nucleoplasm, Nucleoli" "CAB013274: , CAB018389: AB_2217962, HPA026918: AB_10610566, HPA061603: " "unprognostic (3.71e-2)" "prognostic unfavourable (4.53e-4)" "unprognostic (3.88e-2)" "unprognostic (1.25e-2)" "unprognostic (6.28e-3)" "unprognostic (2.40e-3)" "unprognostic (8.98e-3)" "prognostic unfavourable (5.34e-4)" "unprognostic (1.63e-1)" "unprognostic (1.64e-1)" "prognostic unfavourable (7.44e-4)" "unprognostic (3.03e-2)" "prognostic unfavourable (4.01e-4)" "unprognostic (9.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (1.70e-1)" 52.4 31.2 46.3 17.7 54.6 7.3 17.2 36.2 117.8 13.4 14.2 13.3 4.6 14.4 15.0 7.0 18.6 9.0 17.0 33.1 50.2 56.2 15.9 22.0 12.9 12.1 45.9 49.8 13.3 18.0 14.8 7.8 16.6 74.6 14.7 14.0 8.6 10.0 13.3 91.8 11.7 12.5 20.2 22.8 12.7 11.2 8.9 13.5 6.8 8.8 13.8 14.3 14.7 13.2 3.1 5.9 3.2 5.0 1.1 3.3 1.7 37.1 46.7 41.4 52.5 42.4 24.5 18.7 43.2 21.4 26.8 29.2 29.3 40.0 52.4 14.9 38.3 34.8 51.8 47.7 37.8 35.5 22.6 49.6 32.0 32.5 38.7 60.5 48.6 26.8 45.8 31.3 64.9 42.6 68.1 59.3 40.0 35.0 43.2 44.7 45.9 32.8 50.7 41.9 57.9 42.1 25.4 22.2 61.7 47.9 61.4 30.6 42.7 36.7 44.9 52.4 30.5 46.4 57.7 19.7 36.9 80.7 47.1 57.3 55.8 3.2 5.0 1.1 2.1 4.6 3.3 3.1 2.4 2.6 5.2 1.8 1.8 2.0 1.1 1.1 3.8 5.9 2.0 1.7 46.3 54.6 36.2 88.9 50.2 56.2 45.9 49.8 74.6 13.5 AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065379-125143333 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles Vesicles "HPA058815: " "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 21.1 6.5 9.0 10.5 13.0 2.5 33.7 6.6 22.0 11.7 9.3 5.3 7.4 12.9 5.2 7.7 22.3 6.6 12.9 5.8 8.1 5.6 6.8 3.3 4.9 4.9 5.1 13.1 4.9 9.7 5.8 6.7 4.8 10.0 6.7 8.6 5.1 33.7 12.9 3.7 26.9 8.7 4.5 4.2 4.3 12.7 9.7 3.6 6.8 7.6 12.2 8.7 5.0 9.9 3.0 11.8 6.9 2.3 5.8 5.7 3.8 14.5 14.5 6.3 8.6 23.4 15.3 10.6 11.8 11.3 14.0 12.6 18.7 9.7 9.0 12.2 14.2 15.9 11.8 12.7 7.6 9.7 10.8 7.2 9.7 14.2 19.5 5.1 7.3 16.9 10.4 11.9 12.1 10.2 5.0 5.6 8.9 26.6 5.9 6.8 8.0 17.2 1.1 16.1 12.4 14.3 22.2 17.0 4.9 12.5 19.8 9.1 14.8 11.3 9.7 6.8 10.8 7.6 9.0 12.7 7.2 9.8 8.5 8.4 7.4 6.9 2.3 6.7 4.2 0.7 5.4 3.0 3.9 3.2 2.8 1.7 5.7 3.8 0.3 5.8 0.8 11.8 2.4 3.8 9.0 13.0 6.6 22.0 8.1 5.6 5.1 13.1 10.0 3.6 AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 27.7;testis: 8.2" "Cell line enhanced" "Detected in some" "A549: 4.5;SCLC-21H: 5.6;U-266/70: 4.5;U-266/84: 4.7;U-698: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA054321 Supported Cytosol "Intracellular and membrane" Cytosol "HPA054321: " "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" 0.3 0.2 1.2 3.8 0.8 2.7 0.3 1.3 1.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.8 0.4 1.8 0.3 1.2 1.5 0.3 0.3 0.3 3.3 1.7 0.7 0.4 0.3 0.0 0.9 0.3 1.9 0.3 0.0 27.7 0.3 0.3 1.8 3.3 0.7 0.3 1.2 2.2 0.2 8.2 0.3 0.3 0.8 0.3 0.3 0.9 0.3 1.3 1.3 2.2 0.1 1.8 0.2 0.0 0.9 4.5 0.7 0.5 0.0 0.1 0.5 0.0 0.4 0.3 0.1 0.1 3.2 3.7 0.5 0.0 1.1 0.0 0.0 0.3 0.0 1.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.9 0.4 0.5 0.1 0.1 1.2 0.4 0.2 0.2 1.9 0.0 0.1 5.6 0.4 0.1 0.2 1.5 2.8 0.7 0.0 0.0 1.8 0.2 0.1 4.5 4.7 6.6 1.2 0.4 0.8 2.0 0.1 2.2 0.2 0.0 0.0 0.6 0.1 0.0 0.0 1.3 0.0 0.2 0.6 1.8 0.0 1.3 0.1 0.0 1.2 0.8 1.3 0.9 1.2 1.5 1.7 0.7 1.9 0.3 ABAT GABAT ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674565-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 53.3;liver: 136.5;pancreas: 54.2" "Cell line enhanced" "Detected in many" "Hep G2: 44.3;MCF7: 28.5;RH-30: 25.1;T-47d: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria 1500000 Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favourable (5.36e-5)" "prognostic favourable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favourable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 2.1 12.6 26.1 2.7 39.3 1.7 3.2 19.9 43.3 2.2 5.2 10.9 0.1 17.5 2.1 5.0 3.0 2.8 2.7 6.2 20.4 30.9 53.3 136.5 2.8 2.8 24.5 26.1 5.3 54.2 4.0 22.1 2.3 14.3 9.9 4.2 2.6 2.6 2.5 1.4 2.1 8.4 2.1 14.1 2.5 3.9 6.3 11.8 1.0 12.7 0.4 3.3 6.4 1.1 2.2 1.9 8.8 5.8 1.6 2.5 1.8 0.2 0.0 11.8 6.7 1.9 0.6 0.5 1.4 0.8 0.7 0.2 4.4 0.3 1.4 0.5 0.8 3.0 0.7 2.8 0.9 0.8 0.6 1.9 0.0 44.3 3.1 0.4 3.0 2.5 1.2 1.2 0.5 0.2 0.3 1.0 0.2 28.5 0.7 0.2 1.0 0.1 3.4 25.1 0.6 0.4 7.0 1.9 5.7 0.6 0.4 0.0 15.6 1.2 0.2 0.2 2.0 0.9 0.0 1.1 0.1 0.3 0.3 2.0 1.4 1.1 3.1 4.1 2.5 3.6 1.1 0.8 1.7 1.7 1.9 2.2 1.1 1.8 8.8 1.6 5.8 0.3 1.6 1.8 26.1 39.3 19.9 35.1 20.4 30.9 24.5 26.1 14.3 11.8 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 16.6;NTERA-2: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "CAB025115: , HPA007398: , HPA040384: " "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.6 1.4 0.6 0.4 8.9 0.3 0.5 0.3 0.7 2.4 1.1 0.1 1.3 0.4 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.6 3.5 0.8 3.0 1.6 0.7 0.9 0.5 1.8 1.1 7.0 1.4 0.3 1.3 5.1 1.9 20.5 0.7 1.7 5.5 1.0 1.1 2.0 3.9 6.8 0.5 2.5 2.2 1.4 4.0 0.9 0.6 2.7 0.4 1.4 4.0 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449758 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 69.9" "Cell line enhanced" "Detected in some" "MCF7: 17.6;RPMI-8226: 3.1;RPTEC TERT1: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "basal ganglia: 347.3" "Region enriched" "Detected in all" 6 "basal ganglia: 205.1" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: " "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favourable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 13.3 3.0 12.5 3.7 32.0 0.6 9.3 2.6 14.4 4.5 11.7 10.4 3.1 4.2 6.2 4.4 13.8 5.3 7.3 69.9 10.4 8.3 5.3 2.4 2.6 2.0 15.0 8.6 10.1 5.7 1.1 7.7 4.8 9.7 13.8 4.6 4.6 3.1 16.3 2.2 1.1 4.8 13.5 8.8 4.7 9.6 5.9 16.0 0.0 1.0 0.2 2.6 9.5 8.5 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 1.5 0.1 0.1 0.1 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.3 0.2 0.5 0.8 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 1.0 0.1 0.0 0.4 3.1 6.3 0.6 2.2 2.0 0.0 0.6 0.1 0.0 0.1 0.0 0.1 1.5 0.1 0.3 0.2 0.7 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 12.5 32.0 2.6 14.4 10.4 8.3 15.0 8.6 9.7 16.0 ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904943-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;lymphoid tissue: 16.5" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 19.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065887 Supported Supported "Secreted in other tissues" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favourable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 2.1 0.5 2.5 16.5 7.7 0.1 1.6 2.1 12.5 3.4 2.6 0.8 0.0 0.1 4.0 0.1 2.2 0.5 12.3 1.0 1.2 18.4 0.6 0.3 1.7 1.6 2.8 6.2 0.2 7.7 0.1 4.5 0.3 33.8 1.4 1.4 2.5 2.2 1.0 0.3 0.9 1.3 1.5 5.9 0.2 1.8 3.6 0.2 0.1 0.3 0.0 1.4 3.1 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 7.7 2.1 12.1 1.2 18.4 2.8 6.2 33.8 0.2 ADIPOQ "ACDC, ACRP30, adiponectin, AdipoQ, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842690-186858463 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 176.7;breast: 79.4" "Cell line enriched" "Detected in single" 670 "ASC diff: 84.1" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" 11285000000 1000000000 "CAB046467: AB_1078104, HPA051767: " "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 176.7 1.9 0.0 16.7 0.0 0.1 79.4 0.0 0.1 0.1 23.2 0.0 0.4 0.1 0.1 1.3 0.3 0.1 13.2 5.8 0.0 0.0 0.5 0.1 0.1 6.1 0.0 0.0 0.2 1.3 0.1 0.0 0.1 0.0 0.4 1.4 0.0 14.7 0.6 2.0 1.5 2.1 0.4 0.0 0.1 0.6 0.1 0.0 0.0 0.7 9.5 0.3 1.0 0.9 0.8 0.6 2.4 0.4 0.7 0.5 0.1 0.0 0.0 0.0 0.0 84.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.4 0.6 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.8 0.3 0.5 1.9 0.7 0.4 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10304680-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 133.1" "Cell line enhanced" "Detected in many" "ASC diff: 107.9;fHDF/TERT166: 53.9;HSkMC: 65.9;U-138 MG: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 19 "neutrophil: 62.3" "Lineage enriched" "Detected in many" 19 "granulocytes: 62.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016075 Approved "Secreted to blood" 31000 46000 "CAB016075: AB_628693" "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavourable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavourable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 65.2 18.3 6.8 18.3 12.4 21.1 52.1 2.5 15.0 28.3 23.3 5.9 1.6 4.8 11.6 8.0 26.5 7.9 18.7 28.3 4.7 3.5 17.3 26.1 34.3 15.2 8.0 2.0 19.0 16.0 10.8 8.4 133.1 14.2 13.8 7.0 23.5 9.6 2.1 92.3 28.7 8.0 11.8 12.7 14.6 10.7 11.6 9.9 0.3 15.9 13.3 10.1 76.1 32.4 0.1 0.6 62.3 3.2 0.0 0.0 0.4 5.3 4.2 5.1 1.4 107.9 46.3 8.0 40.8 38.2 38.6 26.6 21.4 6.5 0.0 1.8 53.9 7.6 1.4 6.3 32.5 0.1 1.6 0.1 2.0 2.5 13.7 0.2 0.1 65.9 5.1 4.4 7.1 8.7 0.0 0.0 9.6 0.1 0.0 1.2 9.6 1.6 0.1 0.1 7.6 2.3 7.3 0.1 0.4 15.5 3.4 0.0 4.7 0.0 2.5 56.8 0.8 35.5 5.9 0.4 4.3 1.4 17.0 0.0 16.9 0.0 1.7 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 62.3 0.0 3.2 0.0 0.0 0.4 6.8 12.4 2.5 15.0 4.7 3.5 8.0 2.0 14.2 9.9 ADRA2C "ADRA2L2, ADRA2RL2, ADRARL2" ENSG00000184160 "Adrenoceptor alpha 2C" P18825 4 3766348-3768526 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix, uterine: 35.1" "Cell line enhanced" "Detected in some" "Hep G2: 11.0;MCF7: 18.2;NTERA-2: 6.4;SCLC-21H: 7.0;SH-SY5Y: 8.5;T-47d: 6.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "basal ganglia: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 41.4" HPA057688 Uncertain "HPA057688: " "unprognostic (1.44e-2)" "unprognostic (2.21e-3)" "unprognostic (1.23e-1)" "unprognostic (2.02e-2)" "unprognostic (4.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.12e-2)" "unprognostic (6.69e-2)" "unprognostic (1.88e-1)" "unprognostic (3.71e-1)" "unprognostic (3.24e-2)" "unprognostic (9.08e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (6.48e-2)" 6.5 2.4 2.1 1.0 9.8 0.4 9.2 0.5 2.6 35.1 1.5 0.6 12.8 1.0 20.3 18.0 2.1 6.4 5.5 3.0 1.2 1.0 9.2 1.3 2.0 1.2 0.7 1.6 7.6 4.1 0.5 4.2 27.6 1.1 7.3 0.6 3.6 0.8 24.6 2.6 2.1 0.9 3.0 0.7 7.5 0.7 6.2 2.0 0.2 0.8 1.9 0.5 2.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.1 0.5 0.0 0.2 0.4 0.0 0.0 0.0 2.0 1.2 0.0 2.1 0.3 0.0 0.2 0.0 0.0 0.0 5.6 0.0 0.0 11.0 0.6 0.0 0.8 0.9 0.4 0.0 0.0 0.0 0.4 0.0 2.7 18.2 0.0 0.0 6.4 0.0 0.0 5.9 0.0 0.0 0.3 7.0 8.5 2.5 0.0 0.1 6.0 0.1 0.0 0.0 4.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 9.8 0.5 1.4 1.2 1.0 0.7 1.6 1.1 2.0 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200318-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 41.9;liver: 57.9" "Cell line enhanced" "Detected in some" "HSkMC: 4.0;Karpas-707: 8.5;NTERA-2: 3.8;SCLC-21H: 3.6;TIME: 4.3;WM-115: 16.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 3.6;neutrophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA057900 Uncertain Vesicles Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 6.8 0.2 0.8 1.0 1.2 0.1 3.7 0.3 0.5 0.3 16.5 1.1 0.1 4.6 0.3 7.3 0.3 0.3 4.7 0.9 0.7 0.6 5.3 57.9 0.4 0.5 1.1 0.8 0.3 0.3 0.0 0.7 0.4 0.7 0.4 0.3 0.0 0.4 0.1 0.5 0.5 41.9 0.1 1.1 0.3 0.3 1.8 2.0 0.0 0.7 0.1 0.1 1.0 0.4 0.2 0.1 3.6 0.1 0.6 0.1 0.0 0.0 2.4 0.0 2.1 0.2 3.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 1.2 0.0 0.7 3.6 0.0 0.0 0.0 0.0 0.0 0.0 4.3 1.5 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 16.8 3.6 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 3.1 0.6 0.0 0.1 0.0 0.0 0.8 1.2 0.3 0.4 0.7 0.6 1.1 0.8 0.7 2.0 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687423 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 71.5;liver: 63.1" "Cell line enhanced" "Detected in many" "HDLM-2: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA019544 Uncertain Approved Centrosome Centrosome "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 71.5 5.3 2.3 8.1 2.2 8.4 35.2 2.0 3.0 7.4 20.2 2.2 5.9 31.3 4.7 7.1 11.7 4.1 15.8 12.4 2.8 2.4 10.9 63.1 12.1 11.1 2.5 2.8 5.3 47.7 2.5 6.2 4.9 2.6 5.5 3.3 8.9 12.9 6.2 9.5 7.0 33.6 4.0 1.9 6.8 11.0 5.2 1.9 5.1 13.4 7.0 8.8 6.6 4.9 7.0 20.3 33.2 28.4 2.1 2.5 9.8 14.6 20.6 2.4 11.4 17.7 5.5 10.4 9.7 7.7 6.7 5.1 23.3 29.0 4.8 21.9 5.5 39.7 3.4 6.0 0.7 50.0 15.8 7.1 8.5 5.1 12.2 7.5 17.5 5.3 8.4 5.7 3.0 3.4 8.6 0.8 2.8 26.4 0.5 23.3 6.2 37.5 10.9 8.8 26.6 7.8 9.3 5.5 8.8 12.6 13.3 15.9 8.4 29.5 6.8 8.9 9.1 2.8 6.2 1.2 0.1 3.1 0.1 16.1 8.8 6.0 28.4 33.2 2.2 25.3 2.1 4.1 1.9 2.5 14.9 7.0 1.6 1.8 19.1 2.1 22.2 20.3 2.3 9.8 2.3 2.2 2.0 3.0 2.8 2.4 2.5 2.8 2.6 1.9 AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483813 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.4;epididymis: 49.8" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;CAPAN-2: 2.7;HeLa: 1.5;Hep G2: 2.1;HMC-1: 1.8" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 13 "hypothalamus: 19.4" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in single" 16 "hypothalamus: 18.9" "Region enhanced" "Detected in some" "hypothalamus: 3.9" HPA041017 Enhanced Supported "Secreted in other tissues" "HPA041017: AB_10795498" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (3.61e-1)" "unprognostic (3.34e-1)" "unprognostic (4.68e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (3.17e-1)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-2)" 0.1 9.6 0.1 0.1 1.4 0.0 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 49.8 0.1 0.0 0.1 0.1 0.1 19.4 0.5 0.1 2.1 0.3 0.1 0.3 0.1 0.1 0.0 0.4 0.1 0.2 0.1 0.0 0.3 0.5 0.1 0.1 0.4 0.1 0.1 0.3 0.3 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.2 2.1 1.4 3.8 0.3 3.2 1.0 0.1 0.0 0.4 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 2.7 0.8 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 1.5 2.1 0.0 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.2 0.0 0.1 1.0 0.5 0.9 0.0 0.4 0.3 0.0 3.8 1.4 3.2 2.3 1.6 2.2 0.8 1.1 1.5 1.9 2.1 2.2 0.6 0.3 1.2 2.1 1.3 1.0 0.1 1.4 0.1 0.2 0.1 19.4 0.1 0.3 0.2 0.1 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230702523-230714297 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 309.0" "Group enriched" "Detected in some" 6 "Hep G2: 108.5;THP-1: 41.4" "Group enriched" "Detected in all" 10 "glioma: 275.3;liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" 2420000 110000000000 "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 2.8 3.2 23.6 1.9 25.0 1.4 1.6 17.1 37.0 3.8 2.1 24.2 0.0 1.9 1.7 1.8 2.0 2.3 22.5 30.9 18.0 11.9 9.3 309.0 1.6 1.5 19.5 15.0 1.8 2.3 1.8 2.6 1.5 23.8 2.5 2.2 0.0 1.5 1.9 7.8 1.4 2.2 2.6 29.8 1.4 2.4 2.0 15.9 0.0 1.9 0.5 1.4 3.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 108.5 0.3 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.9 0.0 41.4 0.0 0.0 0.2 0.0 0.1 0.5 7.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 25.0 17.1 20.0 18.0 11.9 19.5 15.0 23.8 15.9 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186612923-186621318 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease mutation, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 269 "liver: 402.0" "Cell line enriched" "Detected in some" 77 "Hep G2: 210.3" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "NK-cell: 1.4" "Lineage enhanced" "Detected in single" "NK-cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" 225100000000 140000000000 "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 402.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 210.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921566 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1;pituitary gland: 17.9" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 26.4" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 1.8 3.1 3.6 1.2 4.4 0.3 1.1 0.5 8.1 0.7 2.1 2.0 0.0 0.7 0.5 0.5 0.6 0.5 1.2 0.4 3.4 4.9 0.4 0.5 1.1 0.5 2.7 4.2 0.6 0.4 0.4 17.9 0.5 5.5 0.5 1.2 2.4 0.9 0.8 0.3 0.9 1.5 0.9 2.1 0.5 0.8 4.9 0.9 0.0 1.6 0.0 0.3 0.6 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.5 0.0 0.0 0.1 0.3 26.4 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 4.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 4.4 0.5 5.9 3.4 4.9 2.7 4.2 5.5 0.9 ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374373 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 55.5;liver: 68.4;pancreas: 51.7" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;HBEC3-KT: 64.0;LHCN-M2: 17.3;TIME: 32.2;U-138 MG: 19.0" "Cancer enhanced" "Detected in all" "renal cancer: 212.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 5.8;neutrophil: 2.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" 7750000 1500000 "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavourable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavourable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavourable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" 55.5 9.6 23.3 13.5 24.7 2.3 33.0 5.1 37.6 3.3 11.8 9.2 0.3 10.6 5.9 1.5 11.8 3.2 8.8 11.4 17.1 5.5 9.4 68.4 9.0 2.7 21.4 3.1 2.9 51.7 2.3 3.3 21.4 36.8 6.7 2.1 2.5 3.9 3.7 5.9 6.5 23.5 6.0 20.6 2.5 4.4 3.7 27.7 0.0 7.1 2.5 3.5 10.7 6.0 0.5 0.3 5.8 0.4 0.8 0.6 0.2 0.0 0.6 0.3 0.9 16.1 3.5 0.1 1.2 0.1 0.2 0.0 0.0 5.9 0.0 8.8 2.4 0.8 0.0 64.0 0.1 0.5 0.1 0.1 0.2 0.1 0.3 0.0 0.0 1.6 0.2 9.8 0.2 4.9 0.3 0.2 17.3 0.5 0.0 0.5 0.1 0.5 0.3 0.0 0.2 3.2 1.1 0.0 0.1 7.4 0.7 1.1 1.9 0.1 32.2 19.0 0.1 9.5 0.0 0.0 0.0 0.0 13.0 0.0 3.5 5.8 0.4 0.9 0.4 0.2 0.3 0.5 0.5 0.4 0.2 0.4 0.3 0.3 2.3 0.8 0.2 0.3 0.6 0.2 23.3 24.7 5.1 37.6 17.1 5.5 21.4 3.1 36.8 27.7 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "ductus deferens: 142.4;epididymis: 38.5;salivary gland: 122.9;seminal vesicle: 93.6" "Group enriched" "Detected in some" 5 "A-431: 33.8;CAPAN-2: 52.0;HaCaT: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA032148: , HPA057356: " "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favourable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavourable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavourable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavourable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 6.9 0.4 1.1 2.1 1.1 0.0 17.2 1.6 1.4 9.7 5.3 1.1 142.4 0.2 14.2 38.5 3.6 11.7 10.6 6.9 1.1 0.2 2.6 24.4 4.4 1.5 1.0 1.0 3.9 4.5 0.5 2.0 6.2 1.5 7.2 1.7 1.7 122.9 93.6 3.4 19.1 1.8 5.7 1.0 1.1 9.5 7.6 0.9 1.1 8.9 8.1 3.8 4.5 5.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 33.8 1.3 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.6 0.0 63.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 4.9 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 10.8 0.2 4.1 0.1 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 1.6 1.4 1.1 0.2 1.0 1.0 1.5 0.9 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151757-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 432.6;tongue: 235.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" 77000000 "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: , HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favourable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favourable (4.57e-5)" "prognostic unfavourable (6.19e-6)" 52.7 3.5 2.7 11.5 3.3 81.4 45.9 0.9 2.5 61.5 8.5 3.6 5.5 2.4 6.9 11.2 432.6 11.9 14.9 8.9 3.2 2.5 9.1 2.1 37.3 7.6 4.3 1.9 11.7 2.4 0.5 6.3 149.5 13.5 12.9 4.4 6.4 93.0 7.2 7.9 11.6 6.4 12.3 6.5 5.9 5.9 5.6 3.1 3.9 21.7 235.4 153.3 18.0 83.1 0.7 98.9 146.2 79.1 27.3 52.5 102.8 65.9 104.2 4.7 4.9 66.5 63.3 0.3 114.3 71.4 47.3 32.1 3.0 59.7 0.1 37.8 99.7 81.2 10.1 69.2 37.5 37.3 0.7 5.0 31.0 0.1 53.1 11.0 2.5 36.4 57.4 47.8 94.0 67.0 20.9 2.8 58.3 0.2 19.4 6.0 5.9 42.4 0.0 26.6 0.2 106.4 14.0 0.0 0.0 39.3 1.0 26.4 0.2 1.7 82.7 55.5 34.9 76.2 58.6 0.4 0.1 0.2 128.1 10.2 83.4 146.2 79.1 141.1 52.2 21.5 52.5 0.7 47.0 45.9 98.9 0.2 13.7 25.4 8.6 27.3 19.3 3.5 8.3 102.8 2.7 3.3 0.9 2.5 3.2 2.5 4.3 1.9 13.5 3.1 AP3S1 CLAPS3 ENSG00000177879 "Adaptor related protein complex 3 sigma 1 subunit" Q92572 5 115841481-115914081 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles Vesicles "HPA049270: " "prognostic unfavourable (1.22e-4)" "unprognostic (2.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.68e-2)" "prognostic unfavourable (3.33e-4)" "unprognostic (2.60e-2)" "unprognostic (3.83e-3)" "unprognostic (4.42e-3)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (1.13e-5)" "unprognostic (1.73e-1)" "prognostic unfavourable (9.57e-8)" "unprognostic (2.73e-2)" "unprognostic (3.62e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-1)" 22.0 13.8 28.6 15.0 28.6 33.0 26.1 21.7 30.8 30.8 22.5 10.4 60.4 17.6 20.6 27.6 23.4 16.7 17.0 17.0 30.7 21.1 11.7 23.8 12.7 18.3 23.7 19.4 23.3 34.8 9.1 20.9 20.9 19.8 15.3 20.8 9.7 26.8 64.1 8.5 15.7 28.9 28.7 20.6 11.5 12.8 26.9 13.2 12.1 19.0 12.7 20.1 21.6 19.7 20.1 23.8 39.8 21.9 11.8 17.1 15.4 19.5 5.0 16.5 8.2 42.5 69.8 10.8 22.9 31.9 20.3 36.0 9.6 18.3 14.9 12.9 28.5 5.7 9.0 38.1 30.3 44.2 15.6 6.5 6.6 14.4 24.3 9.3 12.9 30.9 30.5 16.1 15.3 20.5 6.9 11.5 26.4 4.0 11.2 11.8 10.1 9.5 13.9 23.5 26.0 19.4 5.7 5.8 8.0 32.7 6.2 18.8 11.0 10.6 14.1 27.4 16.7 20.5 15.2 8.5 9.1 17.6 22.5 21.5 10.1 17.6 18.5 39.8 10.9 21.9 17.0 20.1 13.8 14.8 15.4 13.0 12.3 12.4 26.7 11.8 19.0 23.8 17.1 15.4 28.6 28.6 21.7 30.8 30.7 21.1 23.7 19.4 19.8 13.2 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC, WNT signaling pathway regulator" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013349 Supported "HPA013349: AB_1844913" "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 7.2 5.4 40.9 6.4 21.7 8.5 6.3 19.1 39.7 6.8 7.1 10.3 2.0 6.6 6.3 3.9 8.4 5.0 5.5 7.4 37.9 12.9 6.9 6.2 6.7 5.6 23.6 20.7 7.6 4.6 13.8 7.2 5.5 39.1 5.9 6.9 4.0 4.0 4.9 7.0 6.1 8.8 8.1 19.1 6.2 5.4 5.3 20.6 3.6 6.5 2.7 6.2 6.2 3.9 3.8 3.0 12.9 2.9 3.0 3.4 1.1 8.3 7.7 12.8 9.3 10.6 8.8 5.2 13.5 6.4 7.5 8.9 6.1 6.8 16.1 13.1 17.2 6.8 13.1 11.0 12.4 9.6 8.9 12.2 11.1 4.6 5.2 6.1 6.7 7.4 7.6 12.7 8.4 10.4 15.0 5.6 10.9 5.8 7.0 3.1 4.6 2.7 6.0 15.9 7.8 6.9 10.6 13.0 7.8 12.8 5.0 5.5 6.9 5.0 16.6 15.3 7.4 15.0 10.2 4.4 6.6 6.3 8.5 11.4 8.5 10.4 2.9 5.0 3.4 1.4 2.9 3.1 1.8 2.1 2.3 3.8 2.9 2.8 12.9 3.0 2.5 3.0 1.6 1.1 40.9 21.7 19.1 31.4 37.9 12.9 23.6 20.7 39.1 20.6 APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654937 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 52.0" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 104.4" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" "unprognostic (1.50e-1)" "prognostic unfavourable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavourable (9.32e-4)" "prognostic unfavourable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavourable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" 3.8 9.7 10.0 2.8 8.0 0.7 2.3 2.0 10.9 0.9 1.2 21.8 0.0 1.5 1.4 1.0 1.3 0.9 1.1 8.3 9.7 10.3 5.2 1.0 13.6 0.8 13.9 7.6 12.5 0.9 0.9 4.3 52.0 14.5 1.5 1.0 0.0 1.3 1.2 2.9 1.2 1.0 2.5 19.3 1.1 1.1 1.6 10.7 0.0 1.6 0.2 0.9 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.3 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.2 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 1.6 0.0 1.5 0.0 104.4 0.0 0.4 0.5 0.0 0.0 0.1 0.3 5.6 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 0.0 0.0 0.0 0.1 17.7 0.4 0.0 7.6 0.4 0.1 0.0 0.0 7.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.0 2.0 8.1 9.7 10.3 13.9 7.6 14.5 10.7 APOBEC1 "APOBEC-1, BEDP, CDAR1, HEPR" ENSG00000111701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 1" P41238 12 7649400-7665903 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "intestine: 56.1" "Cell line enriched" "Detected in single" 20 "CAPAN-2: 7.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;pancreatic cancer: 6.1;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "unprognostic (2.35e-1)" "unprognostic (3.80e-4)" "unprognostic (7.96e-3)" "unprognostic (1.79e-1)" "unprognostic (4.38e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 23.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 56.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APRT ENSG00000198931 "Adenine phosphoribosyltransferase" P07741 16 88809339-88811944 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026681 Approved Supported Nucleoplasm,Cytosol 1200000 "Nucleoplasm, Cytosol" "HPA026681: AB_1844964" "unprognostic (5.87e-2)" "unprognostic (5.10e-2)" "unprognostic (1.98e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.71e-1)" "unprognostic (1.82e-1)" "unprognostic (6.78e-2)" "unprognostic (8.74e-2)" "unprognostic (9.58e-3)" "unprognostic (1.14e-1)" "unprognostic (2.51e-1)" "unprognostic (4.75e-2)" "unprognostic (1.48e-2)" 22.9 37.1 10.9 33.6 13.2 32.9 31.6 10.1 15.3 22.7 31.1 10.7 33.6 27.1 19.9 28.3 50.7 21.0 30.4 22.5 9.1 8.2 27.7 60.4 30.6 94.2 14.8 10.7 17.9 58.2 19.4 15.6 19.3 11.0 25.1 15.1 13.9 48.2 37.4 26.2 49.8 24.3 18.4 12.1 30.4 27.5 16.0 12.2 37.9 29.5 49.7 35.8 18.5 32.8 65.4 92.1 24.2 70.2 58.2 83.7 104.7 25.4 37.4 7.3 33.0 9.0 17.9 39.1 19.3 17.2 22.8 8.9 38.5 30.9 23.7 37.8 10.9 27.3 12.0 31.7 4.6 16.7 71.6 20.2 17.7 40.2 28.6 13.8 16.5 19.1 34.3 18.1 23.0 28.4 42.4 17.8 11.5 93.8 39.0 40.8 28.2 49.0 42.0 11.4 56.1 25.1 17.3 36.5 22.4 36.8 21.5 20.8 71.0 27.5 18.3 20.6 18.0 16.6 18.9 35.0 29.3 65.2 30.3 36.8 18.1 8.5 70.2 24.2 63.0 57.7 83.7 63.2 81.9 67.5 71.6 65.4 75.9 64.3 4.3 58.2 37.1 92.1 66.1 104.7 10.9 13.2 10.1 15.3 9.1 8.2 14.8 10.7 11.0 12.2 ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014113-65022184 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Focal adhesion sites,Cytosol" Nucleoplasm "Nucleoli, Golgi apparatus, Focal adhesion sites, Cytosol" "HPA044610: AB_10964207" "unprognostic (9.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (4.58e-4)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.07e-3)" "unprognostic (2.34e-1)" "unprognostic (9.85e-3)" "unprognostic (6.43e-2)" "unprognostic (6.87e-3)" "prognostic favourable (7.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (1.24e-2)" 39.6 32.0 37.3 17.7 78.7 19.8 26.8 16.1 46.5 21.2 23.5 34.7 13.4 23.9 26.8 20.2 23.7 35.2 22.4 52.6 34.8 32.7 33.8 6.6 23.1 14.8 36.1 38.2 27.2 29.9 22.5 15.4 25.5 32.7 25.3 15.5 30.3 26.9 33.1 78.3 19.6 23.4 28.2 44.9 16.7 18.9 31.4 28.7 7.9 26.3 23.6 12.9 24.7 22.8 43.7 37.8 18.7 21.8 21.0 40.7 34.7 35.8 57.1 17.7 26.2 48.1 36.6 16.1 17.7 40.9 25.4 25.1 16.1 24.8 13.8 33.8 24.9 23.0 18.6 31.1 12.1 14.5 29.2 13.9 25.8 24.3 36.9 16.9 12.7 28.8 26.1 21.1 47.4 33.7 32.9 25.9 17.0 42.4 14.0 38.1 27.7 46.7 7.4 19.4 33.3 27.3 15.6 33.0 18.6 15.1 15.7 49.7 16.5 20.8 25.3 47.8 16.1 38.0 18.2 8.9 12.5 8.5 22.6 24.5 38.8 10.2 21.8 18.7 34.8 21.2 37.6 43.7 32.2 33.6 27.6 37.3 36.8 40.7 2.8 21.0 12.4 37.8 20.6 34.7 37.3 78.7 16.1 46.5 34.8 32.7 36.1 38.2 32.7 28.7 ARL2BP "BART, BART1, RP66" ENSG00000102931 "ADP ribosylation factor like GTPase 2 binding protein" Q9Y2Y0 16 57245098-57253635 "Disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043066, HPA048440" Approved "HPA043066: , HPA048440: " "unprognostic (1.17e-1)" "unprognostic (4.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (3.33e-3)" "unprognostic (1.26e-2)" "unprognostic (1.47e-1)" "prognostic unfavourable (9.06e-5)" "unprognostic (2.38e-1)" "unprognostic (3.06e-1)" "unprognostic (2.07e-1)" "unprognostic (4.10e-2)" "unprognostic (2.71e-3)" "unprognostic (1.44e-1)" "unprognostic (1.58e-1)" "unprognostic (1.47e-2)" "unprognostic (6.78e-2)" 31.7 29.0 32.0 18.7 35.6 19.5 27.1 30.1 47.9 26.8 23.9 25.5 23.6 13.8 30.4 23.8 33.2 29.9 23.8 38.7 30.2 31.3 36.8 26.9 28.8 24.3 30.8 18.6 36.0 20.8 25.8 26.3 25.5 37.6 27.4 24.2 33.6 20.3 32.2 20.1 21.7 20.1 39.2 20.5 34.9 18.2 53.8 15.7 30.2 24.0 22.6 29.0 29.3 21.6 19.2 27.5 12.8 23.0 29.8 26.6 22.9 20.8 14.6 27.7 14.0 24.6 32.0 6.8 26.2 30.3 30.5 19.5 11.0 8.3 17.5 31.1 36.0 14.1 17.4 21.3 29.0 8.0 16.8 15.4 12.2 17.8 33.8 14.3 33.8 27.3 27.6 22.1 30.5 36.8 11.7 6.7 21.1 7.9 15.0 17.8 9.6 28.5 20.9 27.0 33.9 33.0 7.9 8.6 18.0 40.2 19.4 23.2 14.2 18.8 32.6 18.4 11.3 15.8 20.1 17.4 14.1 17.0 23.8 9.4 17.4 12.8 22.2 12.7 21.1 21.5 22.5 19.2 19.3 23.0 27.5 16.1 26.6 21.6 3.8 29.8 23.0 8.1 15.9 22.9 32.0 35.6 30.1 47.9 30.2 31.3 30.8 18.6 37.6 15.7 ARNTL "bHLHe5, BMAL1, JAP3, MOP3, PASD3" ENSG00000133794 "Aryl hydrocarbon receptor nuclear translocator like" O00327 11 13276652-13387266 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045962, HPA050938" Supported Supported Nucleoplasm,Vesicles "Intracellular and membrane" Nucleoplasm Vesicles "CAB045962: AB_11124144, HPA050938: " "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (9.00e-2)" "unprognostic (1.77e-1)" "unprognostic (3.72e-1)" "unprognostic (3.76e-2)" "unprognostic (8.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (2.10e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (7.08e-2)" 12.3 28.5 13.4 10.3 13.3 13.4 18.2 24.4 25.2 16.4 10.3 5.7 10.6 11.8 10.4 6.5 9.3 9.7 9.4 8.1 11.5 7.5 11.1 17.3 12.1 15.0 6.7 13.1 21.1 9.8 6.1 17.8 9.2 9.3 7.5 8.9 8.6 11.2 8.2 19.2 27.2 10.9 11.7 9.6 10.4 9.6 16.2 9.3 29.2 17.6 0.7 12.2 8.1 17.0 2.8 6.1 20.0 7.8 9.8 19.7 7.3 6.8 6.6 6.1 4.1 11.8 7.6 4.8 6.9 7.4 6.8 8.0 3.3 10.0 0.1 2.2 5.2 2.6 4.8 8.2 5.9 11.7 5.0 3.1 5.4 1.7 21.1 1.4 13.0 9.4 21.7 2.5 18.2 4.8 1.8 12.2 6.8 3.7 3.2 0.7 1.7 3.6 4.2 7.7 3.3 6.6 1.6 1.3 11.9 5.7 2.0 6.6 4.4 5.8 9.3 7.1 5.5 16.7 3.9 3.5 9.4 0.0 7.0 3.6 6.1 4.4 6.7 13.7 14.3 6.9 19.7 2.4 13.4 12.9 6.1 2.8 7.8 9.1 20.0 9.8 7.8 1.1 8.5 7.3 13.4 13.3 24.4 25.2 11.5 7.5 6.7 13.1 9.3 9.3 ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428632-154436516 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Uncertain Approved "Plasma membrane,Microtubules,Cytosol" 160000 "Plasma membrane, Microtubules, Cytosol" "CAB015218: " "prognostic unfavourable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavourable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favourable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favourable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" 29.8 37.8 36.6 20.0 50.3 27.5 22.1 59.2 82.7 28.4 26.5 39.4 27.4 24.0 20.6 43.2 29.1 29.6 23.0 35.1 40.8 47.5 42.4 26.9 37.9 21.8 36.5 40.5 24.4 42.6 67.1 41.5 66.1 60.1 41.6 24.7 29.8 35.9 29.4 18.4 30.2 24.2 22.9 39.4 36.4 27.6 21.2 24.2 22.1 39.7 20.9 21.4 27.3 21.1 20.1 68.4 64.0 56.6 23.7 28.9 33.8 22.4 21.4 18.3 31.1 29.7 16.4 34.4 16.6 23.6 25.9 37.8 20.2 28.1 13.3 70.4 35.6 24.1 26.9 15.4 14.3 12.1 27.8 7.6 27.5 20.0 37.4 12.3 56.5 21.8 26.4 24.3 14.0 35.9 9.1 37.6 16.9 32.9 8.9 18.6 6.8 21.9 13.8 12.2 34.5 27.4 18.8 18.3 19.0 14.5 59.3 31.1 26.1 30.4 27.7 18.9 17.1 32.2 27.0 54.3 58.3 15.7 22.6 26.7 19.0 37.4 53.9 64.0 28.6 56.6 28.9 17.5 23.7 24.7 68.4 20.1 21.4 23.5 60.0 23.7 43.4 39.0 26.9 33.8 36.6 50.3 59.2 82.7 40.8 47.5 36.5 40.5 60.1 24.2 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522611 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.2;parathyroid gland: 65.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" 21000 "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favourable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favourable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavourable (6.90e-4)" 9.4 15.6 19.3 9.3 46.1 9.9 9.1 55.8 66.2 8.0 11.6 25.8 5.1 17.9 11.4 11.1 9.6 9.7 12.2 9.9 23.8 32.8 20.3 11.3 12.7 6.6 23.6 24.8 11.4 9.3 65.6 23.6 11.2 43.3 9.9 11.3 19.7 8.2 10.7 28.9 14.7 12.4 11.7 23.7 11.1 8.8 9.8 13.1 5.2 16.3 6.7 7.8 6.7 6.9 6.3 9.1 14.2 10.5 0.1 2.8 4.2 6.5 13.5 8.3 14.8 14.0 12.1 4.8 4.6 8.6 9.9 13.0 8.6 14.7 1.2 8.5 9.5 14.2 12.7 7.8 11.5 10.1 13.4 10.5 10.2 6.8 8.6 4.5 19.2 9.0 11.3 15.8 6.8 7.0 38.1 41.4 14.7 5.6 1.8 4.0 5.3 0.1 0.1 8.6 18.2 11.4 5.2 22.9 12.2 7.2 6.6 13.7 15.9 6.8 4.1 8.4 0.3 12.3 5.5 16.9 22.9 2.5 11.3 0.1 9.8 12.1 10.5 8.0 0.8 3.4 1.2 3.5 0.6 0.1 9.1 6.3 1.0 0.8 14.2 0.1 2.4 4.7 2.8 4.2 19.3 46.1 55.8 65.9 23.8 32.8 23.6 24.8 43.3 13.1 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712318-123761755 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 13.5 9.4 7.2 13.0 9.9 15.5 11.5 16.2 9.8 8.9 13.1 13.0 9.0 16.0 13.4 8.8 9.1 10.4 10.4 13.6 8.0 7.9 8.9 13.7 13.1 16.6 12.8 6.9 9.7 18.1 8.1 10.4 10.2 9.1 9.8 12.0 9.8 24.5 10.0 13.0 20.5 15.8 12.3 9.4 13.1 15.9 15.9 10.8 24.0 10.3 8.6 17.5 11.0 10.3 2.3 3.4 13.1 1.5 2.1 2.7 0.9 3.2 8.3 8.6 11.6 5.1 4.9 5.3 3.9 4.6 5.1 5.6 6.1 2.6 12.5 2.8 5.3 7.0 11.2 4.1 3.8 8.5 6.3 18.0 6.6 3.5 8.1 11.4 37.1 4.4 3.6 6.0 6.5 4.4 10.9 2.3 5.6 9.0 10.8 14.1 9.0 5.5 10.4 7.5 4.0 4.9 8.1 5.2 8.8 6.6 4.6 5.8 4.8 8.4 6.4 6.5 2.5 7.9 6.5 7.5 8.2 11.7 5.4 6.9 5.5 6.4 0.9 13.1 2.1 0.9 1.5 1.3 2.1 1.8 1.1 2.3 1.9 2.7 2.4 2.1 1.5 3.4 1.4 0.9 7.2 9.9 16.2 9.8 8.0 7.9 12.8 6.9 9.1 10.8 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "kidney: 40.6;salivary gland: 55.4" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 35.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018029, HPA064555" Enhanced Approved Cytosol Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favourable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.1 0.0 0.5 0.0 0.3 0.0 2.2 0.1 0.4 1.7 0.0 0.3 3.1 0.0 0.3 0.5 2.7 0.0 0.0 0.0 0.4 0.3 40.6 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.2 1.0 0.2 0.5 0.0 0.3 55.4 1.2 0.0 6.5 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.0 1.8 7.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.4 1.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 3.0 1.1 0.0 0.1 0.0 0.0 0.4 0.0 2.9 0.1 0.0 0.0 0.0 35.0 1.2 0.1 0.0 0.1 0.4 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.1 0.4 0.4 0.3 0.3 0.0 0.2 0.1 ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 173.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 58.0;granulocytes: 173.6;monocytes: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol Cytosol "HPA044281: " "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (5.69e-2)" "unprognostic (5.31e-2)" "unprognostic (3.92e-2)" "prognostic unfavourable (4.79e-4)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (7.23e-2)" "prognostic favourable (3.24e-4)" "unprognostic (6.13e-2)" "prognostic favourable (3.62e-6)" "unprognostic (5.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "prognostic unfavourable (8.87e-4)" 20.4 35.7 35.4 21.8 35.3 84.2 28.5 29.1 56.4 23.3 28.3 32.2 26.7 19.2 13.9 35.6 21.9 20.0 22.0 24.8 41.2 44.7 47.6 56.3 25.8 28.5 43.6 31.5 12.9 87.0 32.5 36.3 35.0 33.9 27.0 32.0 32.4 34.8 22.2 27.9 20.1 20.2 19.1 34.8 33.2 25.2 15.3 24.8 16.3 38.7 19.5 24.7 23.2 16.5 23.7 58.0 173.6 78.0 8.8 14.2 87.6 23.3 22.8 18.9 23.8 29.2 15.4 23.2 21.0 31.3 40.9 35.4 24.5 25.6 21.7 19.5 22.2 19.4 44.3 31.7 19.3 20.3 46.1 27.2 39.4 35.2 46.3 42.2 52.8 19.0 41.8 45.0 40.0 19.7 27.0 47.7 33.5 24.7 17.4 70.3 31.3 48.8 24.7 18.2 59.2 42.5 28.9 44.7 22.1 14.2 56.1 52.7 23.0 76.0 9.9 21.1 18.0 38.0 50.6 38.6 56.8 24.0 28.7 60.2 33.0 31.9 78.0 64.2 13.2 48.1 13.0 23.7 14.2 12.7 48.1 19.1 10.8 10.9 173.6 8.8 44.0 58.0 13.7 87.6 35.4 35.3 29.1 56.4 41.2 44.7 43.6 31.5 33.9 24.8 ATP6V0C "ATP6C, ATP6L, ATPL, VATL, Vma3" ENSG00000185883 "ATPase H+ transporting V0 subunit c" P27449 16 2513870-2520218 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065100 Approved Cytosol Cytosol "HPA065100: " "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.96e-2)" "unprognostic (7.67e-2)" "unprognostic (2.31e-1)" "unprognostic (4.20e-3)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "prognostic favourable (1.07e-6)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.85e-1)" "unprognostic (5.04e-2)" 56.5 68.2 61.2 53.6 83.5 87.2 24.1 76.0 156.7 27.7 42.9 39.2 25.2 55.2 28.0 21.9 48.7 25.6 23.0 32.5 64.3 70.1 78.0 37.3 40.5 37.1 55.4 74.2 27.2 42.7 41.9 52.3 35.1 70.4 35.7 19.5 40.1 54.3 30.3 108.8 38.7 52.8 18.3 41.9 48.3 59.0 30.4 29.4 25.1 25.7 34.7 29.2 20.8 29.6 15.9 28.2 50.6 42.5 13.0 16.1 18.2 29.4 31.7 17.1 24.4 21.7 10.8 40.9 43.7 13.8 18.3 17.6 29.4 38.2 14.9 40.2 20.9 35.9 18.2 25.9 9.3 37.9 54.3 17.0 25.5 36.0 30.8 26.9 52.5 19.5 19.4 23.1 12.2 13.1 40.3 28.6 15.9 57.5 27.1 70.5 33.2 38.8 43.6 14.9 46.6 32.2 17.6 55.8 45.4 36.8 42.7 35.0 41.1 34.5 31.2 29.5 35.2 44.4 31.2 53.2 64.9 27.2 25.9 19.9 29.9 22.1 32.6 50.6 14.8 36.3 15.1 15.9 13.4 16.1 20.4 15.4 15.6 13.5 43.7 13.0 42.5 28.2 13.2 18.2 61.2 83.5 76.0 123.3 64.3 70.1 55.4 74.2 70.4 29.4 ATP6V0D1 "ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD" ENSG00000159720 "ATPase H+ transporting V0 subunit d1" P61421 16 67438014-67481237 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016938 Uncertain "HPA016938: AB_1845191" "unprognostic (1.12e-2)" "unprognostic (1.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.79e-3)" "unprognostic (8.57e-2)" "unprognostic (2.93e-1)" "unprognostic (1.20e-2)" "unprognostic (8.30e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "prognostic favourable (1.20e-5)" "unprognostic (5.72e-3)" "prognostic favourable (1.76e-8)" "unprognostic (2.72e-1)" "unprognostic (6.42e-2)" "unprognostic (2.63e-2)" "unprognostic (4.33e-3)" 24.2 41.4 32.0 28.2 58.8 31.0 19.8 41.1 89.9 27.9 36.7 35.3 17.1 30.5 26.8 27.4 33.0 26.3 24.7 27.0 40.4 48.5 34.3 30.6 34.5 29.7 39.6 39.1 17.9 25.7 42.5 40.7 30.1 66.6 23.8 33.0 26.6 23.7 26.3 42.5 30.1 29.6 36.0 24.8 37.0 26.9 40.6 18.9 27.6 35.2 21.3 27.4 26.9 22.0 21.1 53.8 106.5 79.7 16.8 16.0 66.3 17.9 25.6 15.9 20.5 40.5 22.0 15.3 21.5 35.3 44.5 53.6 26.6 19.4 7.5 18.1 31.0 21.6 23.4 27.0 26.7 9.1 21.5 13.9 15.0 22.1 38.3 13.8 58.5 34.1 26.8 44.8 10.7 27.6 15.6 10.0 35.9 43.1 10.2 31.4 15.4 18.4 18.3 18.6 20.9 27.0 30.1 31.1 14.5 56.1 15.3 23.2 24.8 21.2 26.5 22.4 9.2 27.4 11.3 16.9 23.8 22.0 31.5 14.8 13.2 29.6 79.7 58.7 16.0 56.9 11.0 21.1 12.0 14.7 53.8 18.9 9.3 11.5 106.5 16.8 51.1 19.3 14.4 66.3 32.0 58.8 41.1 89.9 40.4 48.5 39.6 39.1 66.6 18.9 ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154228 "Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 56.8" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.2;U-87 MG: 9.5" "Cancer enriched" "Detected in many" 9 "renal cancer: 36.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles Vesicles "HPA055327: , HPA058496: " "unprognostic (3.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (8.43e-3)" "unprognostic (5.36e-5)" "unprognostic (4.02e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "prognostic favourable (2.20e-6)" "unprognostic (8.58e-2)" "unprognostic (1.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" 6.6 0.3 0.2 1.3 0.3 0.8 0.3 0.2 0.2 0.2 1.5 0.0 11.9 0.7 0.2 1.0 0.2 0.2 0.1 0.2 0.3 0.3 56.8 0.3 12.2 1.2 0.5 0.0 0.8 0.2 0.3 0.2 0.2 0.0 0.8 2.0 5.7 1.1 1.2 0.2 0.9 1.0 0.0 0.3 0.4 0.3 0.2 0.0 1.0 0.4 0.3 0.6 0.3 0.2 2.2 1.7 4.6 1.0 2.0 1.5 0.3 0.6 1.3 0.7 0.8 0.0 0.6 2.5 0.0 0.0 1.1 0.3 0.3 0.4 0.4 0.3 0.1 2.8 0.8 1.8 0.5 0.4 0.1 0.9 1.8 0.2 0.0 0.8 1.5 0.6 0.1 1.0 0.8 0.5 0.5 0.8 0.5 1.0 0.0 0.8 0.3 0.2 0.2 0.3 0.3 0.0 1.2 3.8 0.3 0.1 0.9 6.2 2.0 0.1 0.3 0.7 0.9 0.8 0.5 0.5 0.2 0.7 9.5 0.7 0.8 2.6 1.0 0.8 1.1 0.5 0.8 1.2 1.0 0.9 0.5 2.2 1.5 1.3 4.6 2.0 1.0 1.7 0.9 0.3 0.2 0.3 0.2 0.2 0.3 0.3 0.5 0.0 0.0 0.0 ATP6V0E1 "ATP6H, ATP6V0E, M9.2" ENSG00000113732 "ATPase H+ transporting V0 subunit e1" O15342 5 172983757-173035445 "Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.24e-1)" "unprognostic (3.08e-1)" "unprognostic (3.61e-1)" "unprognostic (1.51e-1)" "unprognostic (5.34e-2)" "unprognostic (1.54e-3)" "unprognostic (2.25e-3)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (6.63e-2)" "unprognostic (1.47e-1)" "unprognostic (8.33e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" 53.2 54.8 22.3 34.4 26.6 18.1 77.1 9.1 21.5 45.3 50.7 30.6 53.2 28.8 41.8 152.2 53.0 35.6 43.5 70.0 20.0 24.9 90.5 78.6 54.4 68.2 33.3 15.5 49.0 53.1 18.3 65.2 83.1 40.5 48.6 36.3 52.6 59.4 54.6 47.6 34.2 54.1 46.3 34.1 61.3 43.8 34.6 21.9 34.8 91.8 42.2 45.6 56.6 43.5 86.8 90.7 183.9 94.9 50.1 69.0 145.1 31.5 34.5 11.3 34.2 104.9 42.2 26.7 62.0 57.9 31.1 48.3 38.7 49.3 13.7 88.8 72.7 22.8 22.5 44.1 34.8 94.5 22.3 12.9 35.0 36.4 51.3 24.3 45.4 55.6 54.5 35.6 19.8 37.3 8.4 40.5 67.7 62.4 15.1 35.2 13.1 29.8 16.3 16.2 24.6 61.5 40.4 16.5 11.1 27.3 33.7 48.5 37.3 34.1 55.9 74.5 16.6 52.8 51.7 35.0 71.7 15.0 40.2 40.8 24.2 157.8 94.9 141.6 59.4 69.5 54.4 86.8 68.3 61.8 61.0 72.9 66.5 69.0 183.9 50.1 65.6 90.7 67.8 145.1 22.3 26.6 9.1 21.5 20.0 24.9 33.3 15.5 40.5 21.9 ATP6V0E2 "ATP6V0E2L, C7orf32" ENSG00000171130 "ATPase H+ transporting V0 subunit e2" Q8NHE4 7 149872968-149880698 "Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 92.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "unprognostic (8.72e-2)" "unprognostic (4.73e-2)" "unprognostic (3.10e-3)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (2.42e-2)" "unprognostic (5.84e-3)" "unprognostic (3.57e-2)" "prognostic favourable (5.80e-4)" "unprognostic (1.21e-1)" "prognostic favourable (8.26e-7)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.48e-3)" 11.8 17.3 60.1 6.5 56.5 3.6 8.6 70.5 92.7 6.4 6.7 26.4 14.2 5.0 4.3 6.2 6.0 13.4 5.9 27.9 73.7 55.3 26.9 27.9 6.8 12.1 61.1 39.7 4.9 11.7 14.0 25.3 3.1 57.1 26.2 5.3 18.7 37.0 24.8 8.7 4.7 4.6 6.3 29.4 8.3 7.3 3.2 12.2 8.4 26.6 2.0 8.1 4.9 1.7 7.0 6.4 1.5 6.9 12.0 30.6 11.2 7.3 20.8 8.7 28.1 3.6 0.5 5.4 3.8 5.3 10.6 10.9 7.3 9.3 15.1 16.3 5.1 6.6 18.4 6.5 4.6 19.5 20.4 4.7 6.4 41.8 5.2 3.4 10.4 1.2 6.8 11.7 0.7 8.8 5.0 7.4 0.7 12.6 2.4 7.9 7.5 14.7 16.5 0.3 7.0 8.2 8.0 50.1 28.4 5.0 17.5 11.7 9.9 2.3 1.6 3.1 3.3 32.2 14.2 10.4 13.2 7.3 19.6 6.0 10.0 1.5 3.1 0.7 16.7 5.8 15.4 7.0 21.0 19.5 6.4 6.3 27.5 24.7 0.4 12.0 6.9 3.0 30.6 11.2 60.1 56.5 70.5 66.4 73.7 55.3 61.1 39.7 57.1 12.2 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747019-113812056 "Disease related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.6" "Group enriched" "Detected in all" 6 "dendritic cells: 16.4;granulocytes: 33.6;monocytes: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035083, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol 2700000 "Nucleoplasm, Vesicles" Cytosol "CAB006910: , HPA035083: AB_2674453, HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favourable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 12.8 19.8 24.1 10.4 33.2 7.4 12.7 34.8 52.8 14.0 11.1 10.3 5.6 9.3 7.5 8.2 13.2 10.0 10.8 4.7 26.2 38.2 47.9 18.2 12.3 11.4 25.4 25.0 6.2 10.5 39.3 13.5 12.3 52.0 11.2 11.8 14.7 18.0 8.4 4.5 12.6 7.9 8.2 13.6 13.7 10.9 8.9 8.3 9.6 21.0 5.7 13.6 10.2 8.2 3.8 16.4 33.6 15.4 3.8 3.4 6.0 25.0 11.4 14.4 12.5 30.3 13.6 15.3 13.6 20.8 14.3 19.8 21.5 20.2 20.5 32.3 19.8 16.3 32.4 17.9 18.8 9.3 8.9 18.2 17.7 16.5 25.1 13.3 21.3 18.3 12.4 18.5 12.9 23.2 20.8 15.6 21.2 16.4 9.7 6.0 18.0 14.3 8.4 10.4 23.3 39.1 23.9 27.9 10.3 23.8 16.2 17.8 24.6 10.8 21.3 13.3 10.0 9.1 8.1 16.3 17.5 19.0 26.2 16.9 14.8 9.2 15.4 5.2 2.8 11.7 2.6 3.8 2.6 2.7 16.4 2.9 2.5 2.9 33.6 3.8 9.5 4.6 3.4 6.0 24.1 33.2 34.8 52.8 26.2 38.2 25.4 25.0 52.0 8.3 ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935868-70965431 "Disease related genes, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 37.9;placenta: 29.0;salivary gland: 106.9" "Group enriched" "Detected in some" 9 "BEWO: 13.5;HaCaT: 12.4;SK-BR-3: 30.6" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 1.0;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 12 "monocytes: 1.4;T-cells: 1.0" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: " "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" 0.6 0.0 0.1 0.1 0.1 0.0 4.4 0.8 0.2 12.2 0.1 0.1 6.9 0.1 0.5 0.4 0.5 5.0 0.1 0.3 0.1 0.0 37.9 0.1 2.1 0.1 0.1 0.1 2.0 1.1 0.0 1.7 29.0 0.1 0.6 0.0 7.4 106.9 1.1 0.1 11.8 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.3 0.1 1.6 1.1 0.1 0.2 0.0 0.0 0.0 1.4 0.0 1.0 0.0 0.2 0.2 0.3 0.8 1.6 1.9 13.5 0.2 0.1 0.0 0.0 0.0 1.2 0.0 0.1 0.7 12.4 0.4 0.0 0.0 0.3 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.2 0.1 0.3 0.9 0.4 30.6 0.0 0.3 0.0 0.2 0.4 0.1 0.6 0.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.1 0.8 0.2 0.1 0.0 0.1 0.1 0.1 0.1 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197367-20226819 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 116.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 69.7;eosinophil: 47.6;intermediate monocyte: 62.5;myeloid DC: 34.5;neutrophil: 116.0;non-classical monocyte: 54.1" "Group enriched" "Detected in all" 10 "dendritic cells: 34.5;granulocytes: 116.0;monocytes: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles 240000 Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favourable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 17.1 29.9 31.7 25.8 45.0 14.4 13.2 39.2 72.9 12.2 13.9 15.9 5.5 16.2 10.6 12.2 15.3 10.3 14.8 13.9 33.8 47.8 53.9 18.0 22.8 17.5 46.9 47.1 10.9 12.2 18.8 23.6 18.5 64.2 11.0 16.5 17.3 12.8 10.9 18.2 18.2 21.1 15.0 19.2 20.9 10.7 24.0 12.7 10.3 12.7 9.3 17.5 14.3 12.4 4.9 34.5 116.0 69.7 4.8 7.1 51.1 10.7 18.0 22.4 7.3 30.7 19.0 20.2 24.2 15.6 31.3 32.4 20.3 6.3 19.1 9.8 23.1 9.2 17.7 16.1 33.3 8.0 11.9 13.2 8.2 15.5 36.0 9.4 27.7 16.9 14.8 19.4 17.9 19.5 19.7 18.5 33.4 6.1 27.5 11.2 16.6 7.9 11.4 28.9 9.9 28.9 17.0 17.4 25.1 11.7 15.9 77.1 20.6 17.4 20.6 15.7 12.0 25.9 19.3 7.5 10.1 22.5 21.8 22.5 39.8 15.9 69.7 47.6 5.7 62.5 6.2 4.9 5.9 6.1 34.5 4.3 6.1 6.0 116.0 4.8 54.1 8.4 7.1 51.1 31.7 45.0 39.2 69.0 33.8 47.8 46.9 47.1 64.2 12.7 ATP6V1C1 "ATP6C, ATP6D, VATC, Vma5" ENSG00000155097 "ATPase H+ transporting V1 subunit C1" P21283 8 103021063-103073051 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023943, HPA057297" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA023943: AB_1845197, HPA057297: " "unprognostic (5.73e-3)" "unprognostic (3.30e-1)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-2)" "prognostic unfavourable (8.82e-4)" "unprognostic (3.29e-2)" "unprognostic (3.87e-1)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (3.98e-2)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (3.88e-1)" "unprognostic (2.83e-1)" 17.1 23.1 25.1 16.8 36.7 6.5 15.7 26.2 58.8 13.6 11.1 11.4 7.6 12.1 14.1 10.9 10.6 12.2 13.7 19.0 28.5 28.0 35.0 18.1 12.9 15.9 23.2 33.3 14.4 12.9 21.3 29.2 20.2 45.1 13.2 13.7 11.5 10.4 12.2 11.7 8.5 12.8 14.5 15.0 14.3 12.1 13.0 12.5 10.7 26.9 8.4 15.6 15.5 10.7 10.6 16.3 27.9 24.3 10.0 12.5 10.8 29.5 17.8 9.4 7.0 24.7 16.0 11.6 22.2 22.2 24.9 29.5 13.1 30.0 19.0 25.5 17.6 11.9 18.6 17.3 35.7 12.5 14.3 18.6 13.5 15.6 26.4 9.9 22.4 15.3 22.5 33.5 16.1 18.7 23.6 15.7 27.7 13.4 18.6 7.3 8.3 17.2 10.8 16.7 14.4 27.9 21.3 12.1 10.4 12.5 11.9 38.9 24.8 11.8 22.3 14.5 14.7 32.2 15.5 20.5 7.4 18.1 28.1 20.6 14.0 8.4 17.4 20.6 9.1 24.3 10.2 10.6 7.7 8.9 16.3 10.2 9.0 9.7 27.9 10.0 22.1 8.8 12.5 10.8 25.1 36.7 26.2 58.8 28.5 28.0 23.2 33.3 45.1 12.5 ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721649-10785110 "Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 49.3;placenta: 39.0;retina: 54.4;salivary gland: 41.8" "Group enriched" "Detected in some" 8 "BEWO: 39.7;SK-BR-3: 14.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA034734, HPA067305" Approved Uncertain Mitochondria Mitochondria "HPA034734: , HPA067305: " "unprognostic (2.29e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (6.55e-3)" "unprognostic (2.69e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" "unprognostic (6.77e-2)" "unprognostic (2.73e-2)" "prognostic unfavourable (1.12e-11)" "unprognostic (6.17e-2)" "unprognostic (3.30e-1)" "unprognostic (2.37e-1)" "unprognostic (8.27e-2)" 1.4 0.9 0.4 0.4 0.5 1.1 2.4 0.5 0.8 21.2 0.8 0.6 49.3 0.1 2.1 30.5 6.9 0.8 0.8 0.7 0.8 0.3 13.2 2.0 0.8 0.5 0.4 0.4 0.9 1.1 0.1 8.9 39.0 0.5 1.8 0.7 54.4 41.8 15.1 0.4 36.7 0.7 0.4 0.6 1.3 0.6 0.8 0.4 0.9 1.4 6.0 3.5 0.5 7.2 1.1 0.8 0.6 1.7 0.9 2.2 1.1 0.3 0.4 1.2 1.4 0.0 0.0 39.7 0.5 0.0 0.0 0.0 0.7 1.0 1.0 0.8 0.0 0.6 0.6 0.0 0.0 0.5 1.5 0.5 0.6 1.4 0.0 0.9 0.5 0.0 0.1 0.0 0.0 0.0 0.4 1.9 0.0 1.2 0.3 1.5 1.0 0.4 0.8 0.7 3.2 0.0 0.9 1.0 1.3 0.3 14.2 0.4 1.4 2.1 0.2 0.5 1.0 0.5 0.5 3.4 1.0 0.6 0.6 0.8 0.4 0.3 0.8 0.6 2.2 1.7 1.3 1.1 1.0 1.7 0.5 0.9 1.0 0.5 0.0 0.9 0.8 0.8 0.9 1.1 0.4 0.5 0.5 0.8 0.8 0.3 0.4 0.4 0.5 0.4 ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved Nucleoplasm Nucleoplasm "HPA031515: AB_10600785, HPA057316: AB_2683409" "unprognostic (1.10e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (7.10e-3)" "unprognostic (1.52e-1)" "unprognostic (7.64e-2)" "unprognostic (7.78e-3)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.05e-2)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "prognostic favourable (7.60e-13)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" 18.2 51.9 43.9 13.8 47.7 9.9 15.9 23.6 54.1 13.1 19.9 13.5 20.9 16.2 13.8 30.2 33.6 17.9 14.8 52.6 39.8 45.2 52.0 19.9 14.5 11.8 39.7 44.9 10.4 12.4 21.8 28.8 17.2 39.6 21.4 20.3 10.8 15.7 18.1 31.8 14.7 16.8 16.1 29.4 9.7 17.8 14.0 23.0 14.7 34.1 25.2 15.3 16.6 17.0 14.7 35.0 39.2 34.5 17.9 28.5 23.9 60.9 12.7 26.0 16.4 17.4 18.5 18.4 47.1 21.7 28.9 24.2 14.5 21.6 5.0 19.8 28.2 23.0 14.1 22.0 39.1 21.7 9.8 5.3 17.6 11.8 31.9 5.2 19.5 13.2 16.1 20.2 15.3 18.1 11.7 15.5 41.5 14.8 15.2 11.8 18.8 15.3 11.7 21.6 7.9 38.5 24.2 32.6 14.3 30.4 19.7 40.6 28.0 15.4 29.1 43.4 31.7 20.8 30.2 16.5 11.8 7.1 43.5 10.6 24.1 32.2 34.5 37.3 18.6 33.6 15.7 14.7 20.1 20.0 35.0 14.5 15.1 16.8 39.2 17.9 33.3 26.7 28.5 23.9 43.9 47.7 23.6 54.1 39.8 45.2 39.7 44.9 39.6 23.0 ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628818 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009528, CAB018699, HPA029196" Enhanced Approved Nucleoplasm 61000 Nucleoplasm "CAB009528: AB_2062678, CAB018699: AB_781534, HPA029196: " "unprognostic (1.53e-3)" "unprognostic (5.78e-3)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "prognostic unfavourable (1.56e-5)" "unprognostic (2.17e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (7.72e-3)" "prognostic favourable (4.18e-4)" "prognostic favourable (7.66e-8)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (2.75e-1)" 32.8 45.9 59.5 20.4 69.0 24.9 31.5 48.9 90.3 30.2 26.7 34.5 25.2 17.6 27.7 44.4 37.5 26.7 26.7 67.4 58.9 55.4 71.7 26.1 31.7 24.5 54.5 52.3 27.0 15.8 48.3 29.6 46.2 69.8 31.1 32.0 24.1 21.5 42.1 48.5 26.9 19.1 38.1 53.7 23.9 23.8 20.2 32.4 17.5 31.9 26.1 32.5 32.1 22.0 24.2 26.3 55.3 34.8 22.6 29.4 30.1 21.5 19.7 17.8 17.3 59.5 32.2 19.6 28.9 38.6 36.8 42.7 24.4 17.9 13.5 24.9 38.6 34.3 27.8 25.3 32.9 25.9 31.5 24.4 19.7 32.7 87.1 28.0 42.3 40.3 49.7 35.4 25.9 31.0 30.4 27.8 62.6 22.5 24.2 20.3 13.1 27.8 14.2 26.1 8.0 61.0 34.2 13.1 22.8 26.5 18.8 62.2 18.2 32.5 26.4 25.9 13.7 32.3 21.4 27.3 47.8 17.1 41.7 13.7 34.7 45.2 32.9 55.3 21.4 30.8 20.8 24.2 21.9 20.5 26.3 19.0 20.8 21.5 44.3 22.6 34.8 25.4 29.4 30.1 59.5 69.0 48.9 90.3 58.9 55.4 54.5 52.3 69.8 32.4 ATP6V1E2 "ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4" ENSG00000250565 "ATPase H+ transporting V1 subunit E2" Q96A05 2 46490750-46542557 "Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 28.4" "Cell line enhanced" "Detected in many" "hTCEpi: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075092 Enhanced "HPA075092: " "unprognostic (1.62e-1)" "unprognostic (9.65e-3)" "unprognostic (4.31e-2)" "unprognostic (4.39e-3)" "unprognostic (1.02e-1)" "unprognostic (1.52e-2)" "unprognostic (4.52e-3)" "unprognostic (8.56e-2)" "unprognostic (2.98e-1)" "unprognostic (5.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.58e-1)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.98e-1)" "unprognostic (8.07e-2)" "unprognostic (9.32e-2)" 3.4 3.1 6.2 2.7 5.7 1.9 4.0 1.9 7.7 2.7 2.2 5.0 7.0 1.3 2.4 11.4 1.9 2.5 2.3 2.5 4.3 3.5 3.0 2.7 2.4 3.1 4.4 2.9 3.2 9.0 3.0 4.1 2.3 5.1 3.6 1.7 0.8 6.8 6.0 5.6 4.0 2.0 2.4 4.6 3.1 2.5 28.4 4.4 1.6 2.9 0.6 3.1 2.8 4.6 2.8 4.3 1.1 2.1 0.5 4.3 1.1 8.1 5.1 1.7 4.1 1.7 3.2 0.9 2.9 1.1 1.3 0.6 1.6 1.4 4.9 5.3 2.6 2.0 4.1 2.0 2.8 7.5 3.5 1.2 0.9 1.2 1.9 2.0 2.5 2.6 18.8 1.8 4.0 1.3 3.5 8.6 0.8 5.2 1.4 6.2 3.6 4.5 3.4 4.3 6.0 2.5 1.8 4.8 10.3 1.9 2.0 3.9 1.3 0.9 1.2 1.4 5.2 2.4 2.0 4.4 3.4 5.0 2.0 6.3 2.3 0.0 2.1 0.4 2.2 1.0 3.0 2.1 4.0 4.2 1.7 2.8 2.9 4.3 1.1 0.5 1.1 4.3 2.4 1.1 6.2 5.7 1.9 7.7 4.3 3.5 4.4 2.9 5.1 4.4 ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862826-128865844 "Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported "CAB009529: AB_2290237, HPA048700: , HPA062011: " "unprognostic (1.70e-1)" "unprognostic (1.61e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-2)" "unprognostic (2.99e-2)" "unprognostic (8.46e-3)" "prognostic unfavourable (3.62e-4)" "unprognostic (6.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "prognostic favourable (2.49e-5)" "unprognostic (2.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (7.33e-2)" 42.2 44.3 72.8 35.3 66.6 62.7 30.4 49.2 82.8 31.5 26.8 29.2 30.3 26.0 22.6 22.8 62.7 35.7 36.0 38.3 63.0 63.9 65.6 26.0 38.9 42.3 60.7 56.9 27.0 37.2 21.1 33.3 49.6 43.5 27.8 20.3 30.1 44.8 31.3 53.1 44.0 25.3 25.0 43.3 36.8 29.5 41.9 29.8 32.5 31.5 39.2 35.0 39.1 31.3 47.7 73.5 67.4 101.2 32.3 43.9 105.3 43.4 50.3 22.6 47.7 45.3 36.0 12.9 22.2 29.6 36.8 40.0 37.0 26.4 41.2 23.6 25.3 24.1 33.0 36.7 13.8 44.6 53.7 31.5 32.8 36.0 52.5 32.2 60.2 42.2 50.3 42.4 24.6 34.9 74.8 44.1 40.6 57.4 53.7 70.4 30.0 41.3 24.1 16.3 66.8 45.9 34.6 42.8 29.5 31.3 118.2 52.1 27.2 41.1 36.9 45.7 9.9 61.0 33.9 50.1 44.8 52.1 90.4 45.4 38.7 44.8 101.2 67.4 37.8 66.4 36.2 47.7 38.4 36.3 73.5 47.0 37.2 37.4 29.7 32.3 44.0 41.6 43.9 105.3 72.8 66.6 49.2 82.8 63.0 63.9 60.7 56.9 43.5 29.8 ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587746-114598373 "Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli 150000 Nucleoli Nucleoplasm "CAB004615: AB_2258908, HPA042898: " "unprognostic (3.85e-1)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.84e-3)" "unprognostic (2.49e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (3.47e-3)" "unprognostic (9.40e-3)" "unprognostic (4.13e-2)" "prognostic favourable (1.73e-7)" "unprognostic (2.44e-2)" "unprognostic (1.50e-1)" "unprognostic (9.11e-2)" "unprognostic (3.92e-2)" 34.8 66.4 41.5 36.7 38.0 56.6 56.6 37.5 49.4 45.2 34.2 23.4 42.3 26.7 43.7 91.0 57.5 32.3 39.2 45.4 40.8 52.5 84.9 65.9 45.3 50.0 52.2 39.5 49.2 55.9 39.5 79.4 77.8 44.7 65.3 33.2 49.2 63.2 45.1 54.9 40.8 33.2 31.7 35.6 66.5 52.7 58.3 25.6 51.7 65.2 53.5 53.4 45.8 40.1 99.9 81.6 96.6 67.9 50.0 85.1 121.6 17.9 17.3 35.7 8.7 29.6 21.5 33.1 28.1 22.3 23.3 16.7 23.2 21.7 17.4 24.6 20.0 40.8 26.6 21.2 19.6 13.8 18.3 16.7 21.9 33.7 41.5 37.2 31.0 27.4 57.1 18.6 23.2 22.0 32.0 37.0 31.8 39.0 35.9 23.5 42.2 32.7 34.9 22.9 27.9 47.6 30.9 26.9 34.4 37.8 66.1 99.7 53.6 44.2 29.3 19.0 15.1 29.5 31.4 49.9 97.9 30.4 24.5 22.4 26.0 78.3 67.9 96.6 46.7 63.9 57.9 99.9 65.6 56.0 50.9 94.2 85.1 67.1 87.3 50.0 65.8 81.6 76.5 121.6 41.5 38.0 37.5 49.4 40.8 52.5 52.2 39.5 44.7 25.6 ATP6V1G2 "ATP6G, ATP6G2, Em:AC004181.3, NG38, Vma10" ENSG00000213760 "ATPase H+ transporting V1 subunit G2" O95670 6 31544462-31548427 "Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "brain: 91.9" "Cell line enhanced" "Detected in some" "HDLM-2: 6.4;Karpas-707: 7.1" "Cancer enriched" "Detected in many" 11 "glioma: 15.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "CAB004616, HPA068667" Enhanced "CAB004616: AB_667829, HPA068667: " "unprognostic (9.95e-2)" "unprognostic (8.75e-2)" "unprognostic (9.21e-3)" "unprognostic (2.11e-4)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.41e-5)" "unprognostic (1.36e-1)" "unprognostic (7.22e-3)" "unprognostic (3.94e-2)" "unprognostic (1.77e-1)" "unprognostic (3.86e-2)" "unprognostic (1.02e-1)" 2.8 3.3 41.8 3.5 25.7 1.8 1.6 91.9 53.3 1.8 2.3 8.1 0.0 1.5 2.5 2.4 2.2 1.8 1.9 2.9 39.4 27.1 2.6 1.6 2.0 4.7 26.6 29.5 3.1 2.1 2.9 1.2 1.7 43.7 2.6 2.0 2.0 2.0 3.3 4.3 2.0 2.7 2.1 16.3 3.4 1.9 2.7 6.4 0.0 2.3 0.0 4.8 1.7 0.2 0.7 0.7 0.0 0.1 0.8 1.5 0.1 0.2 1.7 3.1 1.5 1.3 1.7 0.0 0.6 0.0 0.0 0.2 0.0 0.9 1.7 0.7 0.6 1.4 0.1 0.6 0.1 6.4 0.0 0.5 0.0 0.9 0.2 0.7 0.6 1.3 0.8 0.5 0.3 0.5 0.7 7.1 0.8 0.2 3.3 1.2 0.0 0.5 0.8 0.0 0.7 0.0 0.0 2.8 3.9 0.0 0.0 0.0 2.1 0.3 1.6 2.0 0.3 0.1 0.0 0.7 1.5 2.4 0.7 0.7 1.4 0.0 0.1 0.0 0.1 0.0 1.5 0.1 0.0 0.8 0.7 0.7 1.2 1.5 0.0 0.8 0.0 0.0 1.1 0.1 41.8 25.7 91.9 53.3 39.4 27.1 26.6 29.5 43.7 6.4 ATP6V1G3 "ATP6G3, Vma10" ENSG00000151418 "ATPase H+ transporting V1 subunit G3" Q96LB4 1 198523222-198540945 "Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "ductus deferens: 16.9;kidney: 33.4" "Cell line enhanced" "Detected in some" "BJ: 2.8;BJ hTERT+: 1.7;fHDF/TERT166: 6.8;TIME: 1.5;U-2197: 2.1" "Cancer enriched" "Detected in single" 140 "renal cancer: 11.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028701 Enhanced "HPA028701: AB_10611681" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 1.7 1.2 0.4 0.0 0.0 0.0 0.6 6.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 0.0 0.0 0.1 0.0 1.5 0.1 1.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715557-53843558 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Approved "Actin filaments,Cytosol" 48000 "Actin filaments" Cytosol "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavourable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favourable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 14.1 25.1 42.2 9.7 41.5 14.0 15.8 22.5 46.2 14.6 12.1 12.0 10.5 8.3 13.7 19.3 18.1 13.1 11.6 17.2 39.0 25.5 36.6 11.3 13.8 11.1 21.4 30.0 15.0 11.7 27.0 20.0 14.0 30.0 19.6 12.0 12.7 16.4 18.2 17.3 14.4 8.3 14.6 14.7 10.2 13.3 10.8 11.3 15.3 30.0 11.5 12.3 15.3 11.0 12.0 16.3 30.6 17.0 18.8 17.7 9.3 19.1 13.4 12.3 13.3 21.9 14.0 10.5 21.3 19.2 24.5 24.8 12.4 22.2 12.2 20.0 17.2 30.1 20.3 26.4 21.7 19.0 16.4 13.4 14.1 15.2 31.8 8.5 15.0 20.9 32.8 16.8 26.2 16.3 16.9 6.0 31.1 13.4 13.5 13.5 12.1 8.0 11.7 4.9 7.7 34.7 25.7 9.9 16.4 12.3 22.1 33.2 28.1 7.3 19.0 10.9 10.0 26.0 11.5 12.8 12.8 14.2 26.2 11.6 11.8 19.0 11.5 30.6 11.5 13.0 13.1 12.0 14.2 13.7 16.3 10.8 13.8 14.3 13.8 18.8 17.0 13.4 17.7 9.3 42.2 41.5 22.5 46.2 39.0 25.5 21.4 30.0 30.0 11.3 BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAI1 associated protein 2 like 2" Q6UXY1 22 38084889-38110670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 59.1;intestine: 80.9" "Cell line enhanced" "Detected in many" "Hep G2: 9.5;RPTEC TERT1: 18.4;SK-MEL-30: 23.0;WM-115: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Region enhanced" "Detected in many" "olfactory region: 4.5" "Low region specificity" "Detected in many" HPA003043 Approved "HPA003043: AB_2227864" "unprognostic (2.15e-1)" "unprognostic (4.23e-2)" "unprognostic (9.82e-2)" "unprognostic (5.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (1.37e-3)" "unprognostic (2.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" 0.8 0.3 2.0 8.1 1.7 0.3 0.7 1.6 3.9 1.3 39.7 0.3 0.1 48.6 0.8 3.4 10.6 0.6 59.1 0.3 2.0 0.8 15.1 1.4 0.3 0.6 0.7 2.6 0.5 0.9 0.2 1.4 1.1 0.2 0.8 7.1 0.3 1.4 0.3 0.6 1.0 80.9 0.6 0.7 0.5 4.7 2.2 0.1 0.1 1.2 1.4 3.5 0.4 1.3 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.3 7.9 0.1 0.1 0.2 1.1 2.3 2.1 0.0 0.0 0.1 7.8 1.1 0.2 3.7 2.0 1.4 0.0 0.2 0.0 0.4 1.2 0.7 0.2 9.5 0.4 0.0 1.3 0.2 0.4 4.1 0.6 0.0 0.4 0.5 0.1 1.3 0.4 0.3 0.8 0.1 0.6 0.0 0.5 18.4 1.4 0.5 0.3 0.4 3.2 23.0 2.4 0.2 0.1 0.1 1.3 0.1 0.0 3.9 0.5 0.2 0.0 0.1 18.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 2.0 1.7 1.6 3.9 2.0 0.8 0.7 2.6 0.2 0.1 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1, Cas family scaffolding protein" P56945 16 75228187-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: " "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavourable (9.11e-5)" "prognostic unfavourable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favourable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 16.6 12.3 14.3 8.4 19.5 1.8 11.5 29.1 26.7 16.7 22.7 31.5 9.1 28.6 17.5 11.0 9.6 10.8 20.4 17.8 14.2 9.4 21.3 17.3 15.9 4.9 18.9 13.5 11.3 31.0 9.2 13.2 28.1 13.9 10.9 7.9 14.6 25.7 12.5 37.4 7.2 25.7 8.6 10.4 28.9 28.7 17.3 20.1 0.2 11.8 9.7 6.3 13.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.2 7.9 2.6 3.0 2.8 15.2 12.8 7.4 9.4 7.4 20.7 13.9 0.8 17.0 14.2 7.9 2.6 14.6 2.7 0.0 9.1 0.0 9.8 17.2 7.7 0.0 6.6 8.6 7.3 11.1 5.5 25.4 8.2 0.4 5.5 22.0 0.0 0.5 10.4 10.8 0.3 3.5 3.3 8.6 12.0 9.7 13.9 12.2 2.8 4.9 6.6 2.2 22.8 15.8 13.7 3.9 18.8 3.5 1.9 0.2 9.9 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 19.5 29.1 26.7 14.2 9.4 18.9 13.5 13.9 20.1 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;testis: 51.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 14.0" "Lineage enriched" "Detected in many" 6 "T-cells: 14.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavourable (5.28e-6)" "prognostic unfavourable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 2.3 1.5 0.4 14.1 0.7 20.8 5.3 0.7 0.6 1.9 4.8 0.3 0.2 4.6 0.9 1.4 13.4 0.4 2.2 2.4 0.5 0.4 1.3 2.2 2.4 9.7 0.6 0.2 0.9 0.8 0.0 0.4 6.1 0.5 0.9 5.2 0.2 2.1 0.2 0.6 3.5 4.7 2.4 0.7 6.3 3.2 51.4 0.3 61.6 0.5 14.4 11.7 2.0 3.2 2.5 0.8 0.5 0.0 2.2 14.0 3.0 31.6 29.6 26.7 28.9 1.7 2.8 9.8 24.4 13.7 34.8 22.9 24.2 12.5 32.6 9.9 14.1 16.9 27.0 15.6 30.5 11.0 37.5 21.5 17.5 28.4 0.2 20.7 16.2 0.9 1.1 19.3 14.3 24.6 26.9 27.6 26.7 18.3 44.0 19.8 19.9 52.1 23.0 43.4 25.2 8.2 11.7 33.0 22.8 18.7 21.2 16.6 28.0 19.6 9.2 42.2 37.4 18.2 34.6 20.0 16.1 37.7 15.4 8.7 36.6 0.0 0.0 0.0 0.7 0.0 0.2 2.5 4.3 2.8 0.8 0.3 0.0 0.4 0.5 2.2 0.0 0.3 14.0 3.0 0.4 0.7 0.7 0.6 0.5 0.4 0.6 0.2 0.5 0.3 BMP8A ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491646-39525935 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "thyroid gland: 45.6" "Cell line enhanced" "Detected in some" "U-2197: 15.9;U-266/70: 7.7;U-266/84: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.7 1.0 1.7 1.2 2.0 0.9 0.5 0.8 3.6 3.3 1.0 8.5 0.0 1.4 3.7 1.2 0.7 2.0 2.6 1.2 1.9 1.3 0.6 0.5 0.7 5.6 4.6 1.1 8.9 3.8 0.5 0.9 1.0 4.8 1.0 0.6 0.4 1.3 1.8 1.4 1.6 2.2 1.9 8.3 1.4 1.0 4.0 2.3 1.7 45.6 0.0 0.6 0.9 0.9 0.7 0.0 0.0 0.6 0.0 0.1 0.4 0.4 0.8 0.4 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.3 0.2 0.6 0.0 0.0 0.0 0.4 1.8 0.0 1.6 0.3 3.8 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.9 0.0 1.6 0.0 2.1 1.1 0.1 0.5 0.3 2.4 0.1 0.1 1.4 0.4 0.1 0.2 1.1 0.7 2.9 0.1 0.0 0.7 15.9 0.0 7.7 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 2.0 0.8 3.6 1.9 1.3 4.6 1.1 4.8 2.3 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Cell line enhanced" "Detected in some" "AF22: 8.9;AN3-CA: 9.7;CACO-2: 7.7;HAP1: 7.2;NTERA-2: 15.0;SCLC-21H: 35.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.9 8.9 9.7 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.7 0.5 0.0 1.3 0.1 0.0 7.2 0.0 0.6 0.9 3.8 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.9 0.0 0.0 15.0 1.2 0.0 0.0 0.0 0.1 0.1 35.0 5.2 1.7 0.1 2.4 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 BSCL2 "GNG3LG, SPG17" ENSG00000168000 "BSCL2, seipin lipid droplet biogenesis associated" Q96G97 11 62690275-62709845 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.3;Karpas-707: 60.5;RPMI-8226: 41.7;SCLC-21H: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favourable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" 6.6 41.6 38.5 3.8 66.3 5.4 13.6 41.0 65.7 20.3 10.6 11.8 13.9 5.4 10.2 77.4 7.6 31.8 11.3 4.7 39.0 81.3 19.0 10.4 11.5 6.6 34.8 27.2 14.1 36.8 35.9 61.0 6.2 32.8 14.2 7.3 12.0 31.1 17.0 6.8 8.8 4.4 7.5 13.2 5.0 10.5 59.5 10.1 9.4 17.2 4.8 5.8 8.9 7.3 19.5 30.8 19.8 33.7 22.1 18.9 25.0 4.0 14.8 10.5 20.2 35.3 12.2 1.8 1.7 9.1 3.4 3.6 2.3 6.3 2.8 3.6 6.5 14.6 1.2 5.2 1.8 7.0 1.1 2.5 8.5 1.8 7.1 2.2 3.3 8.0 4.2 6.8 2.7 2.6 1.8 60.5 5.3 10.5 2.6 4.9 31.5 2.9 5.0 1.0 41.7 16.1 0.6 43.7 6.8 6.5 3.5 5.8 9.9 3.2 1.6 4.2 0.9 5.8 0.9 7.6 16.4 3.7 20.9 0.7 3.5 15.4 33.7 19.8 15.8 24.2 17.3 18.2 16.3 16.3 24.8 19.5 17.1 18.1 8.3 22.1 21.7 30.8 18.9 25.0 38.5 66.3 41.0 63.2 39.0 81.3 34.8 27.2 32.8 10.1 BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794686 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.1;MCF7: 5.7;RPTEC TERT1: 9.7;SK-BR-3: 6.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 17 "plasmacytoid DC: 1.7" "Lineage enriched" "Detected in single" 17 "dendritic cells: 1.7" "Not detected" "Not detected" "Secreted to blood" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favourable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" 3.0 1.2 1.0 5.2 2.2 0.0 3.7 0.3 2.8 2.2 23.5 1.2 3.1 3.0 2.4 5.6 9.9 6.1 10.3 2.5 1.3 1.3 3.7 0.8 3.4 0.2 0.8 1.0 3.6 2.9 5.2 4.5 0.9 2.1 3.7 5.9 7.0 6.8 3.6 0.6 12.4 11.3 8.3 0.6 0.4 6.9 0.8 0.9 0.4 5.2 1.9 2.3 5.6 3.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 3.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 16.1 0.0 3.4 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.1 0.6 0.0 0.2 0.0 0.0 0.0 1.2 0.3 0.1 0.1 0.0 0.1 0.4 5.7 0.1 0.0 0.0 2.4 0.0 0.0 0.0 9.7 4.6 0.2 0.0 2.3 6.4 0.0 0.4 0.0 0.0 0.3 0.1 0.3 2.8 0.3 0.0 0.0 2.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.0 2.2 0.3 2.8 1.3 1.3 0.8 1.0 2.1 0.9 CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease mutation, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 77.9" "Group enriched" "Detected in some" 5 "SCLC-21H: 30.5;U-87 MG: 17.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 4 "cerebellum: 77.9" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064258, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA064258: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favourable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" 2.2 5.3 7.6 1.0 12.2 0.7 0.9 77.9 19.7 0.8 1.5 1.8 0.0 3.9 1.2 2.8 0.7 2.2 0.8 1.1 5.7 5.1 0.7 0.5 0.7 1.3 3.9 7.3 1.1 3.0 0.7 1.5 0.6 7.2 0.8 1.7 1.2 0.9 0.8 1.3 0.7 2.8 0.9 3.3 1.3 7.7 1.9 2.8 0.0 0.7 0.0 1.0 0.8 0.3 2.8 0.8 1.9 1.1 0.8 0.8 0.4 0.0 0.1 0.0 3.8 0.1 0.3 0.0 1.6 1.5 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 2.0 0.0 1.2 0.0 0.0 0.0 4.5 0.1 0.0 0.0 0.1 0.9 0.2 0.4 0.0 0.1 0.0 0.1 30.5 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 17.2 0.0 0.4 1.9 0.4 0.7 0.5 0.5 0.8 2.8 0.5 0.3 0.4 1.7 0.6 0.7 1.6 0.8 1.1 0.8 0.6 0.4 7.6 12.2 77.9 17.4 5.7 5.1 3.9 7.3 7.2 2.8 CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970786-2697950 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease mutation, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 32.5" "Cell line enriched" "Detected in some" 17 "HDLM-2: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 4.2" "Group enriched" "Detected in many" 19 "NK-cells: 4.2;T-cells: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" 3.8 2.5 8.6 6.0 7.7 1.4 2.4 7.1 11.7 11.2 26.5 1.3 7.4 2.4 29.7 4.5 5.2 4.3 7.1 32.5 5.5 4.0 2.7 1.4 4.7 2.0 2.4 6.6 2.7 3.2 1.5 8.1 5.1 3.9 7.9 3.8 6.5 2.4 8.1 2.3 1.7 5.2 28.8 1.9 3.5 7.2 11.3 1.7 0.0 2.0 1.1 1.7 12.6 5.4 0.0 0.1 0.0 0.1 4.2 1.2 0.2 0.0 0.0 0.0 0.0 1.6 1.0 0.1 1.7 2.0 1.1 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.4 46.5 0.4 0.6 0.0 0.0 1.1 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 2.5 0.0 0.0 0.0 0.0 2.1 0.1 0.6 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.5 0.7 0.0 0.0 0.9 0.7 0.0 4.2 0.1 0.1 0.4 0.2 8.6 7.7 7.1 11.7 5.5 4.0 2.4 6.6 3.9 1.7 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 14.1;RPMI-8226: 32.8;SK-BR-3: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9 "basophil: 7.2" "Lineage enriched" "Detected in single" 20 "granulocytes: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favourable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.6 13.4 10.0 0.8 12.6 1.4 3.6 12.2 16.5 11.2 2.8 3.7 0.1 3.3 6.8 13.2 1.2 14.9 6.2 1.8 5.3 3.5 4.2 3.0 9.0 0.5 2.5 9.6 1.2 5.3 3.0 13.6 1.4 8.7 5.7 3.1 10.1 1.1 3.5 0.6 1.5 4.2 1.7 2.2 4.4 1.8 3.0 1.6 0.0 5.2 0.0 0.6 2.3 0.6 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.1 32.8 0.3 2.2 3.0 1.3 0.2 6.2 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 7.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.0 12.6 12.2 16.5 5.3 3.5 2.5 9.6 8.7 1.6 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 30.8" "Cell line enhanced" "Detected in some" "CACO-2: 4.0;NB-4: 2.5;NTERA-2: 2.9;SCLC-21H: 2.3;U-266/70: 7.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.6 3.0 17.9 2.1 19.7 3.1 0.5 3.9 22.5 0.6 0.8 1.3 0.0 0.6 0.6 4.4 1.1 2.3 0.6 0.6 30.8 5.8 3.8 0.6 0.6 1.4 2.4 10.6 0.5 0.6 0.5 0.2 0.8 4.2 0.5 0.8 0.5 0.5 0.5 0.6 0.5 1.1 1.0 5.2 0.9 0.8 2.8 2.4 0.0 0.6 0.0 1.0 0.6 0.1 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 1.0 1.3 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.0 7.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 17.9 19.7 3.9 22.5 30.8 5.8 2.4 10.6 4.2 2.4 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362799-50504244 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lung: 86.1" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 64.9" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles 1000000 Vesicles "HPA034771: AB_10603555, HPA071829: " "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavourable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favourable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.9 1.6 1.3 11.1 1.1 1.4 14.9 6.5 1.1 1.7 0.9 0.6 1.4 1.7 1.2 0.9 1.1 0.9 7.6 1.7 9.1 1.6 0.5 86.1 1.3 3.9 3.2 2.2 4.0 3.8 6.0 1.9 6.1 3.0 2.0 6.1 1.5 1.4 1.7 2.6 1.7 1.4 1.4 1.5 4.1 5.8 2.5 0.2 2.3 0.1 0.7 0.7 0.7 1.8 0.3 0.7 0.1 2.3 3.6 1.1 0.0 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2.6 0.1 0.0 0.0 0.2 0.0 0.0 6.2 64.9 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 2.2 0.0 2.7 1.8 2.6 2.0 0.0 1.3 3.6 2.2 0.0 2.3 0.1 0.3 3.2 1.1 1.6 11.1 14.9 6.5 1.7 9.1 3.9 3.2 6.1 2.5 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavourable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.2 22.9 10.2 20.4 16.6 13.7 8.1 10.7 7.5 13.6 9.7 25.9 10.1 22.6 9.7 9.8 14.3 30.0 14.2 10.2 14.8 24.2 32.3 17.4 13.5 8.3 25.4 16.3 10.4 11.7 19.7 22.5 14.5 22.7 12.6 11.9 25.4 16.2 37.8 24.5 17.4 28.4 30.6 23.5 10.0 12.9 20.5 10.3 15.0 10.7 12.5 8.3 10.7 13.0 20.6 17.0 16.0 21.5 26.2 16.9 46.2 8.3 24.5 17.7 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell line enhanced" "Detected in all" "PC-3: 45.4;SK-BR-3: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 10.9 7.9 7.1 13.6 5.2 8.6 8.4 7.5 12.9 10.4 8.5 12.2 11.8 8.1 7.9 9.7 17.0 5.6 6.4 8.3 7.3 6.7 5.5 6.1 5.5 2.6 7.5 9.3 4.5 5.8 10.3 7.2 8.8 6.0 12.1 5.7 7.6 12.5 11.2 5.2 45.4 11.4 7.5 4.3 5.4 15.9 3.7 8.6 4.3 57.2 3.7 10.7 4.7 10.8 7.7 12.4 4.2 10.1 3.7 4.4 7.5 8.3 21.5 2.7 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719163-71721048 "FDA approved drug targets, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "adrenal gland: 67.5;brain: 101.4" "Group enriched" "Detected in some" 7 "NB-4: 1.0;SH-SY5Y: 3.4" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 179.9" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavourable (4.36e-4)" "unprognostic (1.14e-1)" 1.6 67.5 8.0 2.8 22.3 0.5 5.8 0.1 29.0 0.5 3.4 2.1 0.0 3.5 0.6 0.9 3.5 0.7 0.6 0.5 31.1 101.4 0.5 0.5 0.5 0.5 1.0 4.5 0.5 5.3 0.5 1.7 0.5 54.1 3.3 3.1 1.6 0.5 0.5 0.5 0.5 1.4 8.1 8.6 0.5 3.4 1.9 9.7 0.0 3.4 0.0 0.5 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 22.3 0.1 29.0 31.1 101.4 1.0 4.5 54.1 9.7 CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183683-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "parathyroid gland: 155.3" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 4.0" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA039686, HPA050335" Enhanced "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 21.0 0.0 0.1 0.2 18.1 0.5 0.0 0.0 0.1 0.0 0.6 12.1 155.3 0.6 0.0 0.2 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.5 0.3 0.0 0.1 1.6 0.0 0.1 0.7 0.0 1.4 0.5 1.1 0.3 0.8 1.1 0.2 0.6 1.3 0.7 1.1 0.3 0.3 0.7 0.7 0.0 0.0 0.1 0.6 0.8 1.1 0.9 0.4 0.5 0.2 0.2 0.3 0.8 0.1 1.4 1.1 1.1 0.0 0.7 0.8 0.4 0.4 0.4 0.2 0.2 0.6 2.0 0.3 0.7 0.5 0.9 1.4 0.6 0.6 0.5 0.6 4.0 1.5 0.6 0.8 0.9 0.5 0.3 0.9 0.3 1.3 1.0 1.8 1.0 0.3 1.6 1.1 0.5 0.7 0.6 1.0 1.0 0.3 0.1 0.9 0.2 0.9 0.7 0.9 0.9 0.1 1.4 0.7 0.6 1.1 0.8 0.2 0.5 1.1 0.2 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 CAT ENSG00000121691 Catalase P04040 11 34438925-34472062 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 258.3;liver: 184.8" "Cell line enhanced" "Detected in many" "HL-60: 75.2;THP-1: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 13 "eosinophil: 258.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 258.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles 960000000 Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favourable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favourable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 70.0 33.0 9.4 10.1 9.6 54.2 36.1 3.1 7.7 15.3 26.6 18.6 15.7 22.2 13.5 9.5 14.8 14.2 19.0 22.4 10.7 5.2 50.4 184.8 26.1 21.3 14.5 6.0 11.0 24.7 7.1 5.0 16.4 10.2 23.2 11.3 11.4 14.5 13.2 27.8 19.7 29.2 11.6 11.3 17.9 15.9 6.2 11.6 23.4 41.7 14.9 11.5 20.4 24.9 7.6 19.9 258.3 17.5 5.5 5.0 17.8 6.1 6.8 5.0 7.8 48.4 21.1 10.6 7.8 9.9 8.8 9.7 3.8 6.2 15.2 7.6 15.5 14.7 8.4 8.5 9.8 13.2 7.7 12.8 7.3 21.9 5.7 75.2 6.4 11.3 5.9 2.6 1.0 10.6 26.5 6.3 11.1 5.8 15.4 13.4 0.0 16.6 10.9 23.8 12.4 24.1 23.3 2.6 4.0 8.8 14.2 11.6 20.3 62.8 7.5 5.3 5.2 13.2 4.6 5.1 2.9 3.2 10.4 51.8 3.8 12.5 17.5 258.3 3.2 14.7 3.8 7.6 3.8 3.6 19.9 6.8 3.8 4.0 17.1 5.5 15.5 13.4 5.0 17.8 9.4 9.6 3.1 7.7 10.7 5.2 14.5 6.0 10.2 11.6 CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 48.1;HBEC3-KT: 55.0;LHCN-M2: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 82 "basophil: 31.8" "Lineage enriched" "Detected in single" 318 "granulocytes: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles Vesicles "CAB013488: AB_2533493, HPA044810: " "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavourable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavourable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" 61.9 4.5 3.0 9.5 6.6 0.2 39.9 1.0 3.7 26.3 15.7 3.1 10.3 3.3 23.4 19.6 25.2 10.8 31.3 54.6 4.4 3.1 9.5 17.4 59.4 6.0 7.5 3.8 17.7 16.0 1.4 2.8 35.2 4.6 20.6 5.0 12.1 10.7 10.5 15.3 13.3 8.3 34.0 8.6 25.3 8.9 12.1 5.3 1.7 61.2 23.2 4.9 29.5 15.4 0.0 0.0 31.8 0.0 0.0 0.0 0.2 38.7 10.5 0.4 0.0 18.0 19.3 0.8 27.1 32.3 9.0 8.1 2.0 48.1 0.0 32.5 27.8 37.7 0.5 55.0 13.0 0.0 2.6 0.3 8.1 0.0 11.0 0.0 0.1 11.3 31.8 12.1 25.1 28.9 1.9 1.5 59.3 2.0 0.0 0.0 0.5 6.8 0.4 13.2 0.5 33.1 1.1 0.0 0.0 20.7 0.7 5.0 0.0 0.2 41.3 0.0 5.7 18.0 8.8 1.7 0.0 0.1 3.6 0.0 19.4 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 3.0 6.6 1.0 3.7 4.4 3.1 7.5 3.8 4.6 5.3 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 169.0" "Cell line enriched" "Detected in some" 4 "NB-4: 71.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 157.7;memory CD8 T-cell: 169.0" "Lineage enriched" "Detected in many" 4 "T-cells: 169.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Secreted to blood" 21766000 8200000 "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favourable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favourable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavourable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 3.6 2.4 0.0 28.8 0.1 17.1 2.6 0.0 0.2 6.0 14.7 1.0 0.6 7.1 5.0 7.2 5.2 1.7 20.5 7.5 0.0 2.7 4.7 29.8 33.5 2.8 0.0 5.9 2.3 0.0 0.1 4.8 1.7 7.8 4.0 8.0 5.5 6.4 2.8 0.0 38.7 2.3 2.2 38.8 6.9 1.9 0.0 12.2 1.6 5.5 27.9 11.5 0.0 1.2 1.1 9.9 0.6 40.8 169.0 106.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 2.4 2.8 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.2 0.0 0.1 11.3 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.0 71.3 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 16.7 0.0 0.0 0.0 0.1 0.0 2.1 0.7 0.1 0.0 15.3 0.1 9.9 0.6 0.7 157.7 0.4 103.8 1.2 36.7 169.0 1.1 0.7 8.8 99.3 4.6 40.8 0.5 0.9 0.5 106.5 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934933-42050357 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 129.2;lymphoid tissue: 142.5" "Cell line enhanced" "Detected in all" "MOLT-4: 92.5;REH: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA071369" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Nuclear bodies" Cytosol "CAB000116: , HPA071369: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favourable (8.08e-6)" "unprognostic (2.11e-1)" 20.2 39.8 16.1 28.9 17.5 74.7 36.0 13.3 19.8 13.3 17.3 11.3 14.1 16.0 10.8 10.4 13.5 13.4 19.0 16.3 15.4 14.5 13.7 8.0 32.1 83.8 14.1 15.5 11.1 10.9 5.0 10.1 21.9 9.3 14.2 11.4 10.2 18.1 14.4 6.5 14.6 22.0 11.7 11.5 51.2 18.0 7.4 10.0 142.5 26.8 9.3 32.8 13.0 16.6 24.1 42.4 129.2 45.8 39.0 52.8 66.2 9.0 33.1 3.5 7.7 6.3 12.9 40.2 10.6 6.1 11.0 8.1 6.2 4.1 39.0 18.0 7.1 5.6 9.2 13.0 5.7 6.6 6.0 61.8 14.8 5.0 13.9 10.1 54.6 12.3 8.5 10.6 4.0 13.5 31.1 3.8 15.7 12.2 92.5 48.5 1.5 7.1 87.9 13.5 4.3 25.4 6.1 11.8 3.1 9.0 11.6 5.2 7.1 39.5 22.5 12.2 6.7 10.6 11.9 2.5 1.9 60.9 7.1 21.3 7.4 129.2 30.5 87.7 52.8 35.1 37.0 16.4 36.4 42.5 42.4 24.1 42.8 45.0 42.8 39.0 45.8 27.8 23.2 66.2 16.1 17.5 13.3 19.8 15.4 14.5 14.1 15.5 9.3 10.0 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853230 "Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 94.9;seminal vesicle: 104.1" "Cell line enhanced" "Detected in some" "Daudi: 49.8;Karpas-707: 13.9;MOLT-4: 12.6;REH: 10.0;U-266/70: 10.8;U-698: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 15.3" "Group enriched" "Detected in all" 4 "B-cells: 9.0;dendritic cells: 5.1;NK-cells: 15.3" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favourable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 4.1 3.3 3.8 17.6 8.5 9.3 2.6 0.7 12.0 1.0 3.2 10.4 14.6 4.3 0.7 0.9 2.3 2.4 1.5 5.0 4.0 4.2 1.2 5.4 4.7 16.1 4.9 3.1 0.6 0.7 0.0 2.5 0.6 3.1 10.8 2.7 4.4 2.8 104.1 14.2 0.5 6.2 0.9 1.8 20.6 2.0 0.7 2.5 94.9 2.8 2.0 13.2 7.6 0.9 9.0 5.1 1.3 2.2 15.3 2.3 3.7 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 13.9 0.0 0.0 12.6 3.0 0.0 0.0 10.0 0.0 7.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 2.2 0.2 0.0 0.0 0.0 0.0 10.8 0.1 9.4 0.1 2.4 0.1 0.0 1.7 0.0 1.1 2.2 0.3 9.0 1.4 1.2 4.1 6.6 2.3 1.8 1.3 15.3 1.4 5.1 2.1 3.7 3.8 8.5 0.7 6.2 4.0 4.2 4.9 3.1 3.1 2.5 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Uncertain "Plasma membrane,Microtubules,Cytosol" "Plasma membrane, Microtubules, Cytosol" "CAB016535: AB_785112, HPA000974: , HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 41.2 31.7 30.4 44.9 22.3 19.2 30.4 19.6 24.2 29.9 22.3 35.6 20.0 9.9 12.5 35.2 23.4 32.3 41.8 20.2 11.9 51.3 10.8 44.5 27.7 29.0 11.3 25.2 23.9 26.8 42.4 51.2 26.7 16.0 16.9 26.1 35.9 9.8 26.0 23.8 34.2 10.5 24.1 17.4 22.5 32.7 25.7 19.4 53.3 41.3 20.2 36.8 13.9 26.8 20.0 32.8 30.5 23.4 13.3 13.0 9.7 17.6 52.7 22.4 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 CEP19 "C3orf34, MGC14126" ENSG00000174007 "Centrosomal protein 19" Q96LK0 3 196706277-196712293 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 45.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 12.9;eosinophil: 17.5;neutrophil: 45.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047614, HPA071138" Enhanced Supported Centrosome Centrosome "HPA047614: , HPA071138: " "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (5.11e-2)" "unprognostic (9.31e-2)" "unprognostic (5.51e-3)" "unprognostic (4.66e-2)" "unprognostic (3.56e-4)" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (2.36e-2)" "unprognostic (1.91e-1)" "unprognostic (3.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.33e-2)" 3.2 5.2 10.2 5.7 11.7 2.4 2.4 7.3 10.8 3.6 2.3 3.0 2.6 2.0 3.3 6.2 3.2 8.0 3.8 2.4 8.4 9.0 5.2 2.3 3.2 5.0 6.5 6.0 3.8 1.4 6.1 9.2 3.9 8.3 3.5 2.2 2.5 2.3 4.4 1.3 3.3 2.0 3.0 4.4 6.1 1.7 17.5 4.4 8.3 5.1 0.4 6.3 4.0 2.6 1.4 3.4 45.3 1.3 2.3 3.5 1.2 5.1 3.6 5.0 3.1 11.6 9.0 1.5 4.2 8.0 4.6 6.0 1.8 3.5 3.9 12.2 2.1 2.3 3.3 1.1 5.5 5.3 3.4 5.9 1.8 0.5 4.7 2.7 7.6 4.1 5.0 6.0 1.6 1.9 3.2 4.8 4.7 2.7 6.6 4.8 2.6 6.1 7.9 3.1 2.7 4.9 0.5 5.0 3.6 5.8 0.8 6.5 4.5 5.2 1.5 5.4 1.2 8.2 2.8 14.8 14.1 8.0 7.6 6.9 5.2 12.9 1.3 17.5 1.8 0.9 2.0 1.1 2.6 2.3 0.8 1.4 3.5 2.2 45.3 2.3 1.0 3.4 1.4 1.2 10.2 11.7 7.3 10.8 8.4 9.0 6.5 6.0 8.3 4.4 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859643-863630 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "ASC diff: 39.8;THP-1: 56.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 125.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 731723333 8000000000 "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favourable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 161.3 4.6 0.0 16.4 0.0 5.6 96.7 0.0 1.7 44.2 35.2 0.2 42.2 10.9 8.9 89.8 54.1 15.6 59.0 102.0 0.0 0.0 1.9 2.3 34.0 6.2 0.0 0.0 13.7 6.0 1.7 0.1 20.2 0.1 102.0 4.3 3.4 22.7 15.1 40.5 35.8 16.5 97.3 0.1 3.7 19.7 33.6 0.0 0.8 52.6 55.6 9.0 83.7 130.3 0.6 5.6 125.0 25.8 0.1 1.0 10.4 0.7 1.9 0.0 0.3 39.8 6.2 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.5 0.2 0.0 0.0 1.1 2.8 0.0 1.7 0.6 0.6 0.3 1.0 6.3 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.9 0.0 8.9 0.1 2.8 0.2 0.0 0.9 0.0 0.1 0.3 0.3 0.8 0.2 0.0 1.1 56.5 0.0 0.0 0.9 0.4 0.1 1.7 0.7 0.0 0.0 3.3 0.0 125.0 18.2 58.8 0.7 20.1 1.0 0.6 0.5 0.9 5.6 0.2 0.7 0.8 43.2 0.1 25.8 0.5 0.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116104-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 79.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favourable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 35.4 17.6 13.7 29.8 17.4 66.8 31.6 26.9 12.6 20.5 25.7 13.5 31.3 17.5 24.7 27.6 21.0 19.2 22.1 58.1 14.7 7.7 24.9 18.9 58.5 34.3 16.8 8.9 14.6 14.3 9.1 18.7 28.3 12.6 23.2 17.7 20.9 21.8 27.4 113.7 16.7 26.8 30.5 13.8 35.7 19.4 10.9 14.8 17.2 31.2 26.2 31.4 24.1 33.7 5.3 6.6 79.2 12.6 8.7 11.8 7.8 5.1 10.6 7.6 4.5 23.6 18.1 9.4 13.1 22.9 8.7 10.6 12.2 19.4 1.4 12.5 15.2 3.8 2.4 9.9 13.9 38.8 7.4 7.8 9.1 19.8 16.5 5.8 25.9 19.7 9.8 14.6 12.9 44.0 26.3 32.7 15.7 4.3 2.7 23.2 2.6 8.0 2.8 1.8 11.1 10.8 10.7 1.7 3.0 8.8 7.8 10.3 5.5 10.9 47.7 18.2 7.6 6.7 6.4 54.5 17.9 8.7 12.9 4.7 9.0 16.3 12.1 13.5 11.7 12.3 10.3 5.3 10.1 11.0 6.6 4.0 6.4 8.3 79.2 8.7 12.6 4.6 11.8 7.8 13.7 17.4 26.9 12.6 14.7 7.7 16.8 8.9 12.6 14.8 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "Cystic fibrosis transmembrane conductance regulator" P13569 7 117465784-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 103.0" "Group enriched" "Detected in some" 22 "CACO-2: 12.5;MOLT-4: 47.0;U-266/70: 25.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 5 "olfactory region: 6.3" "CAB001951, HPA021939" Enhanced "CAB001951: , HPA021939: AB_1846578" "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.2 0.4 10.5 0.4 0.0 0.3 0.3 0.3 2.5 19.8 0.1 0.8 10.5 0.6 2.1 0.4 0.4 15.8 0.3 0.4 0.3 1.1 1.4 5.7 0.1 0.5 0.1 0.3 103.0 0.0 0.3 0.1 0.1 1.5 12.5 0.1 22.4 0.1 0.3 1.1 24.2 0.3 0.7 0.3 0.6 0.9 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.4 0.3 0.5 0.1 0.1 0.1 CISH "CIS, CIS-1, G18, SOCS" ENSG00000114737 "Cytokine inducible SH2 containing protein" Q9NSE2 3 50606490-50611831 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "HDLM-2: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB034039, HPA040812" Approved Approved "Microtubules,Cytokinetic bridge" Microtubules "Cytokinetic bridge" "CAB034039: AB_2080282, HPA040812: " "unprognostic (2.36e-3)" "unprognostic (7.60e-3)" "unprognostic (2.89e-2)" "prognostic favourable (1.13e-5)" "unprognostic (8.54e-2)" "unprognostic (9.38e-2)" "prognostic favourable (6.98e-4)" "unprognostic (6.97e-3)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "prognostic favourable (9.65e-4)" "unprognostic (1.30e-2)" "prognostic favourable (3.53e-12)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" 11.8 2.8 0.8 9.7 1.9 3.7 38.0 0.6 1.1 5.2 7.5 0.7 15.6 5.9 6.8 5.9 7.4 4.5 6.4 20.8 1.3 1.0 26.1 36.2 20.5 6.4 1.2 0.2 10.6 11.3 1.9 8.6 47.6 3.8 5.6 5.3 2.8 18.4 19.6 54.0 7.0 6.3 2.8 3.5 7.6 5.5 2.5 1.4 13.8 31.3 7.1 7.0 5.9 5.4 0.4 2.8 7.3 4.0 0.8 23.3 8.1 0.6 0.2 0.7 1.5 0.1 0.9 0.6 0.1 0.1 0.1 0.1 0.6 0.1 0.0 0.5 0.2 0.7 1.2 0.9 0.0 80.1 0.2 4.8 0.4 0.6 0.5 0.6 5.8 3.8 0.4 0.1 0.3 0.1 18.8 0.1 0.1 3.6 1.0 4.3 0.7 0.7 0.4 0.3 4.9 1.6 0.7 0.3 1.2 0.2 9.8 0.1 5.5 3.9 0.1 0.2 0.6 0.7 0.3 0.0 0.1 0.0 0.1 5.7 0.1 7.3 4.0 5.3 14.3 2.4 22.2 0.4 23.3 17.8 2.8 0.1 18.3 17.5 3.5 0.8 1.5 1.8 13.9 8.1 0.8 1.9 0.6 1.1 1.3 1.0 1.2 0.2 3.8 1.4 CITED1 MSG1 ENSG00000125931 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1" Q99966 X 72301638-72307187 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 247.1;pituitary gland: 62.8;testis: 89.9" "Group enriched" "Detected in some" 5 "AN3-CA: 17.5;SK-MEL-30: 69.6" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 134.9" "Region enriched" "Detected in many" 5 "hypothalamus: 18.9" "Cell type enhanced" "Detected in some" "eosinophil: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049051 Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA049051: " "unprognostic (7.04e-2)" "unprognostic (3.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-3)" "unprognostic (8.81e-2)" "unprognostic (5.67e-4)" "unprognostic (3.40e-1)" "unprognostic (9.55e-2)" "unprognostic (4.60e-3)" "unprognostic (4.38e-2)" "unprognostic (6.33e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "prognostic favourable (6.10e-4)" "prognostic favourable (3.95e-4)" "unprognostic (2.99e-2)" 0.5 0.6 3.5 0.5 2.2 0.4 6.0 0.9 2.8 1.3 0.5 0.3 5.3 0.5 1.0 247.1 0.4 0.5 0.4 0.4 2.4 18.9 0.6 0.4 0.5 0.4 1.1 0.9 0.5 0.6 0.4 62.8 0.4 2.7 2.1 0.4 27.8 0.4 1.2 0.4 0.4 0.5 1.7 0.5 0.4 0.4 89.9 0.0 0.0 1.7 0.0 0.4 0.4 0.0 0.0 0.8 2.2 0.5 0.0 1.1 1.1 0.1 0.1 0.7 17.5 0.8 0.0 0.6 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 6.3 0.4 0.0 1.8 2.5 0.3 0.1 0.0 0.0 0.1 3.4 0.3 0.2 0.2 0.3 0.0 0.7 0.1 0.1 0.2 0.0 1.3 1.0 1.2 0.0 1.2 0.9 0.0 0.2 7.9 4.1 0.1 1.5 69.6 0.5 0.4 0.0 0.1 0.7 0.1 0.2 0.1 0.1 0.1 0.1 0.2 1.6 0.0 0.5 2.2 0.4 0.0 1.1 0.0 0.2 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 3.5 2.2 0.9 2.8 2.4 18.9 1.1 0.9 2.7 0.0 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55547138 "Enzymes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 9.3 9.2 7.8 5.8 11.7 1.7 8.4 16.2 14.3 12.5 9.5 5.2 9.2 7.1 10.5 8.4 13.9 8.1 6.7 10.5 7.9 7.9 12.4 9.1 8.2 9.4 7.0 9.8 11.7 8.6 18.7 21.9 8.5 8.4 9.7 8.4 5.6 8.2 9.2 16.1 9.4 12.6 13.8 8.3 9.1 9.6 18.5 5.0 4.0 14.7 5.9 5.2 8.4 17.1 2.5 3.6 0.6 3.0 2.9 4.7 1.4 13.4 5.9 5.3 8.3 8.0 8.1 2.6 13.9 11.4 9.7 9.0 3.7 10.7 3.6 7.2 16.1 11.3 6.8 10.8 16.5 4.4 2.4 2.9 6.2 4.6 7.1 4.7 3.4 4.7 10.7 13.4 13.2 9.1 6.6 7.4 14.6 7.4 2.6 2.6 3.8 6.8 1.7 6.1 2.4 7.5 7.3 5.2 4.7 10.0 12.4 6.3 4.2 2.6 12.5 13.2 14.1 4.3 18.7 6.7 4.8 2.3 11.7 4.2 10.4 0.0 3.0 0.6 2.8 3.0 4.7 1.4 3.2 2.5 3.6 2.5 1.9 2.4 0.6 2.9 2.7 2.1 3.1 1.4 7.8 11.7 16.2 14.3 7.9 7.9 7.0 9.8 8.4 5.0 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5" "Group enriched" "Detected in some" 7 "ASC diff: 39.4;HSkMC: 26.0" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 6 "B-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported "Plasma membrane,Actin filaments" "Plasma membrane" "Actin filaments" "HPA042256: , HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 19.4 6.4 18.0 5.2 15.8 1.5 14.9 13.8 30.5 3.9 5.5 0.8 0.8 2.3 3.1 4.7 3.7 5.5 3.6 1.4 17.6 7.7 0.9 0.7 6.4 6.5 2.3 14.7 4.1 1.8 1.3 18.3 5.2 4.2 1.5 5.1 0.0 4.3 4.0 1.7 2.4 4.2 5.8 3.2 2.3 2.3 2.7 2.8 0.0 2.6 0.0 9.9 2.7 3.1 2.9 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 39.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.8 1.3 0.0 2.6 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 3.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 18.0 15.8 13.8 21.4 17.6 7.7 2.3 14.7 4.2 2.8 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.0" "Cell line enhanced" "Detected in many" "SK-MEL-30: 15.8;U-2197: 45.7;U-87 MG: 16.6" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 3.5" "Group enriched" "Detected in many" 27 "B-cells: 1.8;T-cells: 3.5" HPA040396 Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA040396: " "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.1 5.6 7.5 1.6 10.8 0.5 2.1 11.9 15.7 5.2 5.3 9.4 0.2 1.6 4.2 8.7 4.0 9.2 4.3 2.9 6.2 6.2 1.6 0.8 1.9 0.8 12.4 9.0 15.4 1.6 1.4 8.3 0.6 13.0 2.7 2.9 3.9 1.4 4.4 2.2 1.5 2.2 3.9 7.7 0.9 2.6 32.0 8.1 0.0 2.7 0.0 0.8 5.5 3.8 1.8 0.0 0.0 0.0 0.0 3.5 0.6 0.0 1.5 0.1 0.1 1.1 0.0 0.0 1.2 0.1 0.7 0.6 0.0 0.0 0.0 2.7 0.4 0.0 2.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.8 0.0 1.0 0.6 0.0 1.5 0.0 0.0 3.6 0.0 0.5 0.0 0.2 0.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 4.5 1.0 3.9 0.2 15.8 0.0 0.5 0.0 8.3 3.3 45.7 2.5 2.3 5.8 0.6 16.6 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.7 1.8 0.3 1.8 0.0 0.5 1.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 7.5 10.8 11.9 15.7 6.2 6.2 12.4 9.0 13.0 8.1 CPEB2 ENSG00000137449 "Cytoplasmic polyadenylation element binding protein 2" Q7Z5Q1 4 15002674-15070153 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072513 Approved Cytosol Cytosol "HPA072513: " "unprognostic (6.59e-2)" "unprognostic (4.21e-3)" "unprognostic (4.75e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-2)" "unprognostic (2.36e-2)" "unprognostic (5.67e-3)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (8.62e-2)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.34e-2)" 10.0 7.5 18.5 6.0 21.5 23.0 13.6 11.5 21.0 8.8 11.5 28.7 13.2 9.6 8.2 9.4 13.6 7.1 10.7 7.8 17.4 16.2 13.5 18.9 9.5 6.4 27.2 17.4 7.9 5.4 23.8 6.4 7.4 16.4 10.2 10.7 20.7 8.9 21.9 7.1 23.0 9.5 10.8 21.7 6.6 10.8 37.4 27.6 3.6 6.1 7.8 7.2 8.3 12.6 0.4 0.7 2.4 0.4 1.3 1.6 0.3 1.3 8.1 0.8 0.3 6.0 11.1 1.4 4.6 3.1 2.8 2.1 0.2 1.6 0.8 0.9 4.2 1.4 1.7 1.0 1.8 2.2 0.6 0.2 6.2 1.4 2.8 0.3 1.0 5.5 5.4 6.9 6.6 2.6 0.1 5.9 11.6 0.6 0.1 1.8 0.8 1.2 0.1 0.6 0.3 24.7 1.0 0.7 4.5 1.5 1.0 4.6 0.5 5.2 5.0 10.2 0.8 6.4 2.4 3.9 0.5 0.4 8.4 4.6 3.8 0.0 0.4 1.7 0.5 0.4 1.6 0.1 0.8 0.5 0.7 0.4 0.9 0.3 2.4 1.3 0.2 0.3 0.2 0.3 18.5 21.5 11.5 21.0 17.4 16.2 27.2 17.4 16.4 27.6 CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826198 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 98.8" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavourable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favourable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" 7.8 6.5 13.1 2.9 40.7 1.5 2.4 26.3 98.8 2.2 2.5 3.9 0.0 2.8 4.2 1.5 1.6 2.3 1.9 3.0 16.9 7.6 2.4 2.4 2.8 2.4 16.3 18.3 2.4 3.0 3.4 1.7 1.8 52.8 4.4 1.7 3.8 4.4 2.5 4.5 3.0 2.8 2.0 5.4 5.6 3.2 4.9 4.2 0.0 1.8 0.0 1.6 1.7 1.7 0.2 2.3 0.1 0.0 0.0 0.8 0.0 2.7 0.2 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 8.0 0.8 2.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.1 1.1 0.0 1.3 1.3 0.0 0.0 0.7 0.0 0.2 42.0 5.8 0.2 2.7 0.0 4.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 2.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 13.1 40.7 26.3 98.8 16.9 7.6 16.3 18.3 52.8 4.2 CPLX3 CPX-III ENSG00000213578 "Complexin 3" Q8WVH0 15 74826547-74831802 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.8;lymphoid tissue: 31.8;prostate: 56.4;retina: 32.8" "Cell line enhanced" "Detected in some" "Daudi: 5.5;Karpas-707: 4.8;SK-BR-3: 2.7;U-266/84: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" CAB079003 Supported "CAB079003: " 0.4 2.5 6.4 0.5 7.4 0.4 0.4 20.8 19.6 0.5 0.5 3.3 0.0 0.4 0.4 0.5 0.5 0.4 0.4 13.4 6.4 0.8 0.4 0.4 0.4 0.5 0.6 7.9 0.4 0.4 0.4 1.7 0.4 8.2 56.4 0.4 32.8 9.8 0.4 0.4 0.5 0.6 0.4 1.0 31.8 4.6 2.2 1.2 0.0 0.4 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.5 0.0 0.0 0.1 0.2 0.1 0.0 5.5 0.1 0.0 0.2 0.1 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.2 0.2 0.0 0.0 0.0 4.8 0.0 0.1 0.0 0.9 0.1 0.3 0.2 0.0 0.4 0.0 0.1 2.1 0.1 0.0 2.7 1.1 1.6 0.0 0.0 0.1 0.1 0.5 0.0 1.3 3.1 2.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.4 20.8 19.6 6.4 0.8 0.6 7.9 8.2 1.2 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081877 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "liver: 76.8" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 55.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" 22000000000 "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria 790000 Mitochondria "HPA008835: AB_1078563" "prognostic unfavourable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favourable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 18.0 18.3 9.9 9.9 12.1 15.8 24.4 7.0 10.3 12.8 31.9 8.2 14.1 33.7 17.0 7.2 11.2 12.8 14.7 14.6 12.0 6.6 30.6 62.0 13.1 10.1 10.5 8.6 17.0 24.4 16.9 13.8 8.7 10.8 15.6 22.0 19.7 12.9 11.4 6.9 10.3 33.4 16.9 8.7 18.9 16.8 10.4 9.0 17.9 13.2 7.5 7.6 11.3 30.2 2.5 11.9 10.6 8.6 5.7 8.8 2.5 8.3 14.8 2.1 14.5 9.5 8.6 0.6 6.7 5.5 5.3 1.1 0.5 28.3 0.0 24.8 17.6 27.5 18.8 4.0 1.6 13.4 1.8 20.5 16.2 6.8 14.2 11.9 24.9 8.9 1.9 10.6 6.4 18.8 2.1 16.9 4.8 24.0 9.7 21.1 0.2 15.8 27.1 0.3 36.5 12.5 20.9 0.3 9.5 18.5 35.7 5.9 31.9 11.6 18.8 11.6 0.2 23.2 9.6 13.2 16.8 8.5 12.2 8.8 12.6 9.2 7.8 10.6 8.8 8.6 5.1 2.3 5.5 5.3 5.0 2.5 3.4 7.0 3.8 5.7 7.2 11.9 2.9 2.5 9.9 12.1 7.0 10.3 12.0 6.6 10.5 8.6 10.8 9.0 CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176382-66178725 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 209.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.2;SCLC-21H: 2.5" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enhanced" "Detected in many" "hypothalamus: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062111 Uncertain "Secreted to blood" 10000 "HPA062111: " "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" 2.7 0.2 4.1 0.2 2.1 0.3 0.2 0.0 6.7 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 2.7 28.4 0.2 0.2 0.3 0.2 0.4 1.1 0.2 1.3 0.2 0.1 209.9 13.8 0.2 0.2 0.0 0.2 0.2 0.3 0.2 0.2 0.5 0.1 0.2 0.4 0.9 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 2.1 0.0 6.7 2.7 28.4 0.4 1.1 13.8 0.0 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" 390000 "Plasma membrane" "CAB010485: AB_2085043, HPA068087: " "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 37.1 22.1 23.3 15.9 23.7 4.2 40.0 25.1 23.4 23.3 27.2 21.2 31.5 21.4 26.0 27.5 25.9 19.0 27.5 22.0 23.0 21.6 26.0 40.5 25.6 14.6 25.3 18.4 21.4 22.1 22.6 11.8 33.6 24.2 22.4 28.6 18.0 21.2 27.3 27.8 18.1 26.9 29.3 24.0 17.6 21.6 17.9 26.4 13.6 32.5 20.2 15.8 28.8 40.7 5.5 4.7 16.3 4.6 3.0 4.2 1.7 14.8 23.2 17.3 18.4 29.4 24.8 16.2 25.8 21.8 20.4 19.1 29.9 8.8 7.2 12.9 29.6 23.1 23.0 18.6 30.1 3.6 15.7 8.0 15.2 16.4 27.3 3.4 7.1 23.9 22.1 21.1 26.7 25.0 13.5 6.9 28.4 15.1 3.7 4.0 15.7 11.6 7.9 8.7 6.5 26.8 16.1 6.4 16.9 24.6 15.3 17.6 15.0 5.8 26.6 20.6 11.8 21.7 25.3 3.3 5.0 4.5 17.4 6.8 22.4 5.4 4.4 5.4 3.6 4.6 3.6 4.1 3.8 3.1 4.7 5.5 2.9 4.2 16.3 3.0 4.6 4.4 2.6 1.7 23.3 23.7 25.1 22.3 23.0 21.6 25.3 18.4 24.2 26.4 CRY1 PHLL1 ENSG00000008405 "Cryptochrome circadian regulator 1" Q16526 12 106991364-107093829 "Disease related genes, Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018762 Approved Supported "Nucleoplasm,Nuclear membrane,Microtubules" "Nucleoplasm, Nuclear membrane, Microtubules" "CAB018762: AB_2083970" "unprognostic (1.21e-3)" "unprognostic (4.74e-2)" "unprognostic (6.50e-2)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.84e-1)" "unprognostic (3.48e-2)" "unprognostic (3.61e-1)" "unprognostic (4.29e-3)" "unprognostic (1.34e-2)" "unprognostic (6.85e-3)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.82e-2)" "unprognostic (5.08e-1)" "unprognostic (1.85e-1)" "unprognostic (2.25e-1)" 12.2 12.2 8.7 8.5 12.6 9.5 18.3 29.2 10.3 12.4 14.3 12.4 5.0 10.7 14.3 12.9 10.7 15.8 16.3 12.2 10.5 8.7 16.0 13.7 18.0 5.0 17.4 7.3 10.7 12.9 8.6 10.0 13.4 13.1 11.2 8.3 8.7 9.4 11.8 10.8 8.7 17.6 15.9 15.4 10.1 14.6 37.6 15.1 26.5 20.1 6.2 7.5 9.5 18.4 1.7 3.5 6.8 6.4 4.7 13.9 4.7 8.5 8.7 10.7 11.8 7.7 4.9 19.2 9.2 9.8 18.7 12.7 10.0 5.2 0.0 5.8 8.5 5.9 13.7 4.7 20.5 8.6 8.5 8.4 7.8 6.9 9.9 8.6 7.4 4.6 4.9 13.7 13.0 15.5 9.4 7.5 11.5 6.0 19.2 9.7 13.1 12.7 17.2 27.1 3.0 13.1 10.1 19.4 10.0 17.3 11.3 5.5 8.0 4.8 6.8 11.0 11.8 7.5 8.1 13.9 13.0 4.0 5.3 8.2 8.9 6.8 2.5 4.4 11.2 3.8 13.9 1.6 8.5 7.0 3.5 1.7 8.0 7.8 1.1 4.7 6.4 2.3 11.0 4.7 8.7 12.6 29.2 10.3 10.5 8.7 17.4 7.3 13.1 15.1 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavourable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favourable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favourable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favourable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 17.4 13.3 18.2 8.8 27.4 17.2 16.7 29.8 36.5 17.7 12.1 15.4 10.5 7.6 16.2 12.4 11.2 20.8 18.7 39.5 15.6 13.1 15.7 27.8 15.7 6.7 12.7 15.0 26.3 23.4 20.6 16.4 9.3 11.5 15.0 7.3 35.5 14.4 17.1 58.2 24.3 8.5 18.7 10.4 9.2 12.2 17.4 9.6 5.9 23.6 22.4 10.3 17.4 10.6 7.8 5.2 7.6 10.6 10.4 10.4 7.1 1.2 3.6 5.6 6.6 15.3 7.7 12.3 4.3 7.8 5.5 4.1 5.9 2.9 8.4 3.4 9.1 7.4 5.3 4.5 3.8 8.9 4.8 5.5 6.3 8.0 5.8 6.7 7.6 9.0 6.7 4.3 6.8 3.8 10.7 14.4 5.0 4.5 5.7 8.0 15.2 4.4 9.8 8.1 3.9 4.0 6.8 9.0 3.4 7.3 6.6 3.7 8.8 4.8 4.8 7.9 4.8 12.0 3.0 13.4 9.2 6.9 4.8 3.0 4.7 5.7 5.0 7.6 8.7 7.1 7.2 7.8 8.4 9.3 5.2 7.7 10.3 10.4 2.6 10.4 10.6 3.8 6.9 7.1 18.2 27.4 29.8 36.5 15.6 13.1 12.7 15.0 11.5 9.6 CYB5R4 "b5+b5R, dJ676J13.1, NCB5OR" ENSG00000065615 "Cytochrome b5 reductase 4" Q7L1T6 6 83859643-83967424 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 49.6" "Cell line enhanced" "Detected in all" "HDLM-2: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 49.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018992 Approved "HPA018992: AB_1847371" "unprognostic (4.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-2)" "unprognostic (1.72e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (4.77e-1)" "unprognostic (6.77e-2)" "unprognostic (1.39e-2)" "unprognostic (5.44e-1)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.15e-1)" "unprognostic (8.15e-2)" 9.3 8.2 4.5 17.9 9.1 23.1 9.6 11.5 8.4 6.3 10.5 8.0 6.2 10.0 7.2 7.6 11.1 6.1 5.3 10.8 4.9 5.0 8.7 8.6 12.3 23.4 10.2 3.4 6.0 8.5 3.6 10.5 12.6 7.3 6.5 8.2 4.3 9.3 4.3 11.9 6.6 11.0 8.8 12.2 18.8 10.8 21.6 9.7 14.2 5.6 6.6 11.9 10.9 7.6 6.9 11.4 49.6 14.6 3.3 5.6 6.3 5.0 4.4 3.2 4.1 1.8 2.3 5.9 3.4 5.1 5.2 7.5 5.7 3.4 9.3 5.4 2.1 4.3 2.9 4.8 3.9 35.8 6.5 22.5 2.6 3.2 3.3 13.4 20.2 2.9 1.3 3.5 3.6 2.6 8.0 7.2 3.6 1.9 3.5 3.7 1.8 4.2 5.9 11.7 3.3 2.3 5.3 8.4 4.6 4.2 4.1 4.7 2.4 8.0 3.4 5.2 4.3 10.7 10.9 8.2 12.6 5.2 6.0 9.3 5.8 20.8 14.6 42.2 4.4 12.1 3.5 6.9 3.8 3.9 11.4 6.6 2.5 3.9 49.6 3.3 13.1 4.8 5.6 6.3 4.5 9.1 11.5 8.4 4.9 5.0 10.2 3.4 7.3 9.7 CYFIP1 "KIAA0068, P140SRA-1, SHYC" ENSG00000273749 "Cytoplasmic FMR1 interacting protein 1" Q7L576 15 22867052-22981063 "Predicted intracellular proteins" "Cell shape, Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 18.7;intermediate monocyte: 18.5;myeloid DC: 18.2;non-classical monocyte: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 18.2;monocytes: 18.7" "Low region specificity" "Detected in all" HPA068106 Approved 2600000 "HPA068106: " "unprognostic (1.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.85e-1)" "unprognostic (8.20e-3)" "unprognostic (3.94e-1)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavourable (7.39e-4)" "unprognostic (2.93e-1)" "unprognostic (8.56e-2)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "prognostic favourable (4.47e-5)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-3)" 14.0 7.1 11.4 7.6 12.5 0.7 17.0 2.7 13.3 11.2 12.4 15.7 9.4 10.1 10.9 10.5 16.2 8.4 12.1 7.6 10.3 8.2 10.5 11.3 14.2 12.4 7.0 8.6 16.6 23.1 2.8 15.9 9.0 9.8 10.7 6.1 9.6 12.0 5.7 11.9 9.8 10.9 11.1 10.7 11.2 4.7 10.7 1.6 9.7 9.7 6.7 10.2 10.5 1.6 18.2 0.5 18.7 2.9 1.8 6.4 26.4 33.2 17.9 32.3 20.9 23.1 20.5 17.1 17.6 16.3 16.0 29.4 15.3 0.1 16.3 29.8 29.7 19.1 25.9 12.5 15.3 18.6 15.6 15.0 16.0 13.4 5.8 12.4 17.3 18.8 12.9 14.6 23.4 9.1 12.3 15.4 20.4 0.4 7.8 9.6 22.9 9.5 19.4 6.9 28.2 45.9 19.9 17.7 19.3 27.4 15.2 23.2 11.3 19.9 26.5 20.2 9.0 32.7 1.4 3.0 0.2 20.1 10.8 16.2 0.0 18.7 0.2 0.3 18.5 1.8 1.6 1.4 0.6 18.2 0.2 0.2 0.0 0.5 2.9 8.8 2.1 0.9 6.4 DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520989 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease mutation, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;fallopian tube: 32.2;pituitary gland: 36.4;testis: 47.0" "Cell line enhanced" "Detected in some" "AF22: 1.8;BEWO: 5.6;HDLM-2: 4.0;RPTEC TERT1: 2.1;SK-BR-3: 2.9;T-47d: 1.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced "HPA021649: AB_1847913, HPA021843: AB_1847914" "unprognostic (9.61e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" "unprognostic (1.44e-3)" "unprognostic (3.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (4.38e-1)" "unprognostic (1.51e-1)" "unprognostic (8.16e-3)" "unprognostic (8.14e-2)" "unprognostic (2.74e-2)" "unprognostic (3.77e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" 0.4 0.4 2.3 0.4 8.0 0.4 0.9 0.3 3.1 2.2 0.4 3.6 0.0 0.4 1.3 6.8 0.4 32.2 0.5 0.4 2.7 3.3 0.9 0.5 4.3 0.4 1.0 0.2 3.5 1.2 1.9 36.4 0.4 14.6 0.5 0.4 1.3 0.4 0.5 0.4 0.4 0.4 0.4 0.6 0.4 0.6 47.0 1.5 0.0 0.5 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 1.8 0.7 0.2 0.0 5.6 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.3 0.0 2.9 0.8 1.9 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 8.0 0.3 3.1 2.7 3.3 1.0 0.2 14.6 1.5 DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" 17 142789-181636 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Group enriched" "Detected in some" 8 "HAP1: 7.2;SH-SY5Y: 28.4" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043168 Uncertain "HPA043168: " "prognostic favourable (3.45e-4)" "unprognostic (2.28e-3)" "unprognostic (3.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "prognostic favourable (8.68e-4)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.78e-3)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (2.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (4.87e-3)" 11.1 7.7 9.1 4.6 10.6 11.0 4.5 23.1 12.6 2.6 1.9 0.2 0.2 1.0 2.8 1.1 8.1 4.8 2.2 2.8 15.5 2.8 0.3 2.6 2.8 0.4 9.9 0.5 6.7 0.9 1.1 3.2 6.6 2.2 2.3 7.6 0.4 2.4 2.1 2.2 2.3 4.1 4.2 2.8 1.7 0.2 2.1 0.0 0.7 5.7 8.4 2.2 10.5 0.8 1.1 1.8 1.1 0.7 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.4 0.3 0.5 0.7 0.4 0.5 0.3 0.3 0.2 0.8 0.3 0.3 1.6 0.7 1.1 1.1 0.3 0.1 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992241-162074542 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 133.1;parathyroid gland: 75.5" "Cell line enhanced" "Detected in some" "ASC diff: 41.8;ASC TERT1: 42.4;BJ hTERT+: 38.9;RPTEC TERT1: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 26.7" "Lineage enriched" "Detected in many" 10 "T-cells: 26.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB045970 Enhanced "Secreted in other tissues" 170000000 "CAB045970: AB_11140529" "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.98e-4)" "prognostic favourable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favourable (4.99e-4)" "unprognostic (1.21e-2)" 9.5 2.9 0.3 3.2 0.5 0.0 5.0 0.3 1.4 2.2 50.0 0.2 36.9 19.1 2.2 3.5 1.2 1.2 5.2 2.1 0.4 0.3 29.1 12.2 5.4 2.1 0.4 0.2 2.7 1.8 75.5 0.3 24.0 0.2 21.1 2.8 0.6 46.9 38.8 2.4 4.4 133.1 0.9 0.8 5.0 1.2 0.6 0.1 6.2 1.0 1.4 1.1 1.0 2.6 0.1 2.1 0.3 0.0 2.6 26.7 2.5 0.0 0.0 0.1 0.0 41.8 42.4 0.1 7.7 38.9 2.1 7.6 7.8 0.2 0.0 2.9 13.4 0.2 0.1 0.0 1.3 2.4 0.1 0.0 0.0 11.7 17.1 0.0 0.0 4.8 0.0 13.1 0.1 1.2 0.0 0.0 0.7 0.0 0.7 0.1 0.4 16.0 0.0 0.0 0.1 56.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.9 4.5 0.2 0.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 26.7 0.1 8.3 5.2 0.6 0.0 8.3 3.3 0.3 2.6 0.0 2.1 0.9 2.5 0.3 0.5 0.3 1.4 0.4 0.3 0.4 0.2 0.2 0.1 DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409615-113475691 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 17.3;brain: 52.0;pituitary gland: 51.6" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 44.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "basal ganglia: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "basal ganglia: 183.8" "Group enriched" "Detected in many" 9 "basal ganglia: 126.7;midbrain: 41.7" "HPA015139, HPA015691" Supported Supported "HPA015139: , HPA015691: AB_1847834" "unprognostic (8.49e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-4)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.40e-2)" "unprognostic (8.33e-4)" "unprognostic (1.10e-1)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (4.82e-2)" "unprognostic (8.49e-3)" 0.6 17.3 0.9 0.5 52.0 0.2 2.1 0.2 3.3 1.3 0.6 1.5 0.0 0.3 2.3 0.4 0.9 2.1 0.6 0.5 0.3 4.1 0.3 0.2 0.6 0.2 9.9 0.2 0.3 0.4 0.3 51.6 0.2 2.4 1.5 0.9 3.9 5.1 1.7 1.7 0.3 0.5 3.2 0.2 0.2 0.5 1.6 9.5 0.0 0.2 0.0 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.5 0.0 0.0 4.7 0.0 0.0 0.0 44.2 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.9 52.0 0.2 3.3 0.3 4.1 9.9 0.2 2.4 9.5 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" 650000 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: " "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavourable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 45.5 48.5 128.5 34.4 97.8 21.9 54.3 48.4 120.5 50.6 61.8 61.9 31.1 31.6 47.2 64.9 113.7 107.1 46.7 44.2 124.1 105.2 49.7 40.7 40.3 41.2 92.9 90.7 49.0 45.7 30.4 46.4 49.8 67.4 39.9 64.5 24.8 34.0 54.9 15.0 117.3 38.9 75.2 93.6 30.4 45.1 59.4 56.8 35.4 37.1 84.3 65.6 59.0 63.0 55.0 80.6 73.6 55.0 46.7 63.4 50.8 78.4 89.7 89.0 68.2 78.2 83.0 28.6 108.6 50.2 88.7 53.2 84.5 52.9 44.0 58.7 103.7 70.8 105.7 90.8 88.7 58.3 69.2 43.0 64.3 114.3 79.0 44.8 71.5 50.4 97.2 66.5 54.6 92.1 53.9 50.7 117.0 103.9 58.5 97.6 73.0 104.7 59.8 46.1 54.6 126.7 72.7 61.2 45.2 88.5 76.9 98.6 76.2 65.6 70.8 68.3 58.3 60.2 93.5 30.6 58.7 43.7 75.7 70.1 87.4 73.6 49.5 63.6 37.7 51.4 28.7 55.0 39.0 39.0 49.1 36.5 25.2 31.5 9.1 46.7 55.0 80.6 63.4 50.8 128.5 97.8 48.4 120.5 124.1 105.2 92.9 90.7 67.4 56.8 EEF2K eEF-2K ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206282-22288732 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 3.9;HMC-1: 4.7;NB-4: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm Nucleoplasm "CAB007818: AB_598150, HPA056061: " "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 16.8 5.5 5.3 8.6 3.7 7.6 12.4 17.5 4.8 14.3 10.7 1.3 9.4 5.6 13.2 8.3 6.1 8.2 12.5 9.0 3.2 3.3 3.7 5.5 9.2 6.7 2.4 4.9 6.4 8.1 3.3 3.0 6.4 4.9 12.5 4.6 4.4 12.4 20.5 16.2 37.5 5.1 15.5 1.6 6.1 6.4 4.6 3.1 4.0 4.4 11.5 6.7 13.3 14.2 0.7 2.3 2.2 0.9 1.3 1.6 0.1 0.1 0.0 0.0 0.0 1.0 1.3 1.0 0.0 0.0 0.2 0.0 0.7 0.0 0.9 0.4 0.0 3.9 0.6 0.0 0.0 0.3 0.0 1.6 0.7 2.7 0.0 3.7 4.7 0.0 1.0 0.2 0.3 0.2 0.5 3.3 0.0 0.0 0.2 4.0 0.4 0.0 1.0 2.6 0.7 1.1 0.0 1.0 1.5 0.0 0.0 0.4 0.5 1.2 1.3 2.4 0.9 3.6 0.1 0.7 0.3 1.1 2.7 2.7 0.4 1.5 0.8 0.6 0.5 0.9 0.7 0.4 0.3 0.2 0.2 0.7 0.7 0.3 2.2 1.3 0.5 2.3 1.6 0.1 5.3 3.7 17.5 4.8 3.2 3.3 2.4 4.9 4.9 3.1 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376889-107670895 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 19.3;RPTEC TERT1: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 3.5;memory CD8 T-cell: 3.0" "Group enriched" "Detected in many" 7 "NK-cells: 2.5;T-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: " "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavourable (1.92e-7)" "prognostic unfavourable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 5.3 1.9 1.9 2.3 6.0 0.0 7.3 10.1 22.2 15.0 4.2 0.9 2.5 1.2 1.6 2.8 9.1 3.9 3.6 8.3 2.5 5.3 5.3 0.6 7.0 3.2 2.1 8.9 5.5 0.7 6.9 18.5 3.1 4.8 6.2 3.6 3.3 11.2 6.8 1.1 13.3 2.3 2.8 3.5 6.3 3.1 1.8 1.1 0.1 2.5 6.0 3.3 4.0 8.1 0.0 0.0 0.4 0.1 2.5 3.5 0.4 6.2 11.1 19.3 0.0 9.3 8.1 1.8 0.2 3.3 2.4 6.0 0.1 7.0 0.0 10.6 1.2 6.5 10.7 9.2 2.3 0.0 6.5 0.0 6.1 0.0 1.8 0.3 0.0 8.6 8.8 0.0 7.8 7.6 0.0 0.0 4.6 6.0 0.0 0.0 2.3 0.9 0.0 8.7 0.2 29.4 8.1 2.9 7.7 3.0 4.5 1.9 1.9 1.2 0.1 14.6 2.6 8.9 3.5 0.5 0.0 4.0 6.4 0.4 15.7 0.2 0.0 0.1 3.5 0.0 0.0 0.0 0.8 3.0 0.0 0.0 0.3 1.4 0.4 2.5 0.1 0.0 0.1 0.4 1.9 6.0 10.1 22.2 2.5 5.3 2.1 8.9 4.8 1.1 EGR1 "AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225" ENSG00000120738 "Early growth response 1" P18146 5 138465490-138469315 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 57.1;U-266/84: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 3.5;intermediate monocyte: 5.1;neutrophil: 9.9" "Group enriched" "Detected in many" 8 "granulocytes: 9.9;monocytes: 5.1" "Group enriched" "Detected in all" 6 "amygdala: 88.4;basal ganglia: 148.1;cerebral cortex: 237.4;hippocampal formation: 138.8;olfactory region: 126.1" "Low region specificity" "Detected in all" "CAB019427, HPA029937, HPA029938" Supported Enhanced Nucleoplasm Nucleoplasm "CAB019427: AB_2097038, HPA029937: , HPA029938: " "unprognostic (5.47e-2)" "unprognostic (4.09e-1)" "unprognostic (1.57e-1)" "unprognostic (7.74e-2)" "unprognostic (6.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.80e-1)" "unprognostic (2.96e-1)" "unprognostic (7.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (3.51e-3)" "unprognostic (3.57e-2)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" 78.7 47.9 5.5 114.3 23.3 18.3 28.7 23.7 25.0 61.8 40.5 31.6 8.0 6.8 51.7 15.6 47.2 187.3 158.4 42.9 7.0 8.1 22.0 68.8 39.7 18.6 4.9 7.0 130.9 23.0 15.8 43.3 24.3 17.8 45.2 21.7 56.1 18.7 100.5 19.4 54.2 29.8 60.8 4.4 8.8 46.1 14.7 2.8 19.4 76.6 67.5 26.6 43.2 20.3 0.9 0.9 9.9 5.1 0.1 0.2 0.4 4.1 0.1 8.9 13.2 24.2 39.2 1.0 7.1 4.4 9.6 7.8 5.0 3.6 0.2 1.1 15.4 1.9 0.5 14.4 4.4 0.2 0.6 0.5 1.7 1.4 3.1 1.5 11.4 3.0 57.1 8.5 1.9 0.8 20.9 5.1 2.8 20.5 0.6 6.4 0.8 0.0 0.1 1.3 0.7 7.3 2.5 11.2 1.2 8.6 23.9 18.5 0.3 1.2 0.3 3.5 4.5 1.7 2.7 11.9 86.2 1.7 4.0 19.6 1.0 0.0 3.5 0.4 0.2 5.1 0.0 0.9 0.1 0.1 0.9 0.3 0.2 0.2 9.9 0.1 1.4 0.0 0.2 0.4 5.5 23.3 23.7 25.0 7.0 8.1 4.9 7.0 17.8 2.8 EGR2 KROX20 ENSG00000122877 "Early growth response 2" P11161 10 62811996-62919900 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 57.1" "Cell line enriched" "Detected in some" 6 "U-87 MG: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "intermediate monocyte: 5.5;non-classical monocyte: 5.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 10 "amygdala: 2.5;basal ganglia: 3.8;cerebral cortex: 4.9;hippocampal formation: 4.1;olfactory region: 3.0" "Group enriched" "Detected in many" 4 "basal ganglia: 3.7;cerebral cortex: 6.6;hippocampal formation: 5.1;midbrain: 3.0;olfactory region: 9.8" HPA031165 Supported Nucleoplasm Nucleoplasm "HPA031165: " "prognostic favourable (7.30e-5)" "unprognostic (1.86e-3)" "unprognostic (1.45e-2)" "unprognostic (8.72e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (9.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-3)" "unprognostic (6.54e-2)" "unprognostic (1.74e-2)" "unprognostic (3.46e-1)" "unprognostic (1.11e-3)" 9.4 4.7 1.8 8.3 9.2 2.7 7.8 1.2 9.9 8.5 2.9 18.7 0.5 0.7 5.8 25.5 3.5 6.1 13.1 16.1 3.3 1.6 3.0 5.2 15.7 5.3 6.0 1.2 7.6 2.2 3.9 10.6 4.9 7.5 7.6 1.5 7.8 3.1 1.3 1.2 15.9 3.1 6.7 3.1 3.6 3.0 4.3 0.7 22.7 57.1 5.0 11.5 8.2 2.4 1.2 1.1 1.5 5.5 0.5 0.4 0.6 0.0 0.2 2.4 1.0 1.8 2.4 0.4 0.5 0.2 0.5 0.8 0.0 0.3 0.6 0.0 0.6 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 3.8 0.3 0.6 1.3 0.2 0.1 0.2 0.8 0.1 1.2 0.0 1.7 0.2 1.3 0.1 0.2 0.4 0.0 0.2 0.1 0.3 0.2 0.8 3.9 0.0 0.5 0.1 0.6 0.4 0.2 0.3 1.4 0.6 0.3 22.4 0.4 0.4 0.0 1.1 0.4 0.4 5.5 0.0 1.0 0.0 0.2 1.1 1.2 0.0 0.4 1.5 0.5 5.3 0.0 0.0 0.6 1.8 9.2 1.2 9.9 3.3 1.6 6.0 1.2 7.5 0.7 EIF6 "b(2)gcn, EIF3A, ITGB4BP, p27BBP" ENSG00000242372 "Eukaryotic translation initiation factor 6" P56537 20 35278911-35284985 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA040873 Enhanced Supported Nucleoplasm 150000 Nucleoplasm "HPA040873: " "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.06e-1)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.24e-1)" "prognostic unfavourable (7.25e-5)" "unprognostic (9.94e-3)" "unprognostic (4.97e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.51e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (9.18e-2)" "unprognostic (8.15e-2)" 21.5 24.9 13.7 21.7 13.1 14.3 21.4 12.4 20.3 26.9 29.5 13.4 15.7 33.7 22.5 19.4 59.9 25.2 29.7 14.4 13.1 14.3 39.9 63.7 18.3 27.9 13.1 15.8 22.1 35.6 17.7 15.6 30.8 13.7 21.2 29.0 14.7 27.0 22.7 14.9 40.6 43.2 22.8 11.1 21.4 20.6 24.1 10.9 31.0 30.7 49.7 43.8 24.1 29.8 51.3 64.0 70.4 60.4 47.4 39.3 60.5 36.7 54.0 13.5 15.4 16.9 20.3 17.4 24.5 29.5 51.9 39.4 100.1 34.6 26.5 28.9 30.2 29.1 27.8 78.3 32.9 6.3 18.5 42.9 21.3 72.0 32.0 22.6 20.9 20.4 50.7 40.4 79.4 35.5 27.8 13.1 54.6 36.1 13.1 30.0 16.2 45.3 18.3 22.3 23.1 67.0 26.1 22.7 19.2 18.8 74.8 26.7 36.3 17.7 27.9 56.6 24.1 28.7 32.8 14.3 15.3 21.9 27.9 24.2 31.3 70.4 55.8 46.1 36.7 55.8 39.2 51.3 35.6 39.3 64.0 49.7 29.1 34.2 18.8 47.4 60.4 59.6 38.1 60.5 13.7 13.1 12.4 20.3 13.1 14.3 13.1 15.8 13.7 10.9 ENY2 "DC6, FLJ20480, Sus1" ENSG00000120533 "ENY2, transcription and export complex 2 subunit" Q9NPA8 8 109334324-109345953 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024648 Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA024648: AB_2100208" "unprognostic (2.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.18e-1)" "unprognostic (7.85e-2)" "unprognostic (7.70e-2)" "unprognostic (7.45e-3)" "unprognostic (1.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "prognostic unfavourable (7.17e-6)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (2.66e-1)" 31.9 35.0 28.7 28.1 34.3 44.4 34.8 20.6 31.4 28.2 34.5 18.7 28.3 31.8 24.6 33.8 30.1 22.9 19.1 34.0 31.8 26.2 44.1 58.8 24.7 26.6 27.6 28.3 19.6 27.8 16.5 35.8 30.6 29.1 24.0 33.7 19.9 27.2 25.9 66.7 20.3 31.6 28.4 31.9 30.6 29.0 21.3 24.3 26.1 24.3 29.5 30.3 29.6 23.3 14.0 32.1 30.3 38.9 13.0 14.6 22.6 42.1 35.3 52.5 23.6 20.0 25.7 15.1 33.7 21.8 34.6 43.8 26.1 26.3 27.5 31.7 26.2 21.6 23.5 23.9 42.3 43.5 27.8 52.7 26.5 53.6 21.4 18.1 32.9 19.4 16.4 22.8 21.6 52.0 50.1 15.5 39.3 68.7 54.7 41.2 38.1 34.5 34.9 22.8 34.0 46.7 32.4 31.7 34.2 21.1 26.6 28.8 33.8 31.4 35.3 23.3 39.3 24.0 34.1 26.6 28.3 52.0 23.5 30.6 27.1 16.3 35.6 30.3 10.7 37.1 13.2 14.0 14.6 13.0 32.1 9.6 12.1 13.3 19.4 13.0 38.9 26.5 14.2 22.6 28.7 34.3 20.6 31.4 31.8 26.2 27.6 28.3 29.1 24.3 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.5" "Cell line enhanced" "Detected in some" "PC-3: 7.0;TIME: 9.4;U-138 MG: 19.7;U-2197: 12.0;U-251 MG: 15.2" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.9 2.7 17.6 1.0 9.0 0.8 0.8 1.9 25.5 5.9 1.2 1.5 1.8 0.9 1.9 0.9 1.1 1.0 0.9 2.7 17.3 6.8 0.9 0.8 1.1 0.9 5.4 13.2 6.2 0.8 0.8 6.5 2.7 10.2 4.2 1.1 2.6 1.2 4.1 0.8 1.2 0.9 1.4 17.7 1.5 1.1 2.2 0.7 0.0 3.0 0.0 0.8 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.3 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.1 1.9 0.0 0.0 0.0 0.0 7.0 0.0 2.2 0.4 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.0 0.0 9.4 19.7 2.5 12.0 15.2 0.0 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.0 1.9 24.7 17.3 6.8 5.4 13.2 10.2 0.7 EPM2AIP1 "FLJ11207, KIAA0766" ENSG00000178567 "EPM2A interacting protein 1" Q7L775 3 36985043-36993168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (7.24e-2)" "prognostic favourable (2.70e-4)" "unprognostic (6.24e-2)" "unprognostic (5.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (2.28e-1)" "unprognostic (5.32e-3)" "unprognostic (1.71e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-2)" "unprognostic (7.73e-2)" "unprognostic (4.30e-3)" "unprognostic (1.03e-2)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (2.25e-3)" 9.7 14.4 13.0 12.9 20.1 14.4 15.2 31.9 25.9 15.4 10.2 14.2 11.1 9.6 17.6 21.2 9.4 14.3 10.7 16.0 13.5 22.4 12.3 12.4 12.3 14.3 18.5 19.3 23.2 9.9 22.2 30.1 10.0 25.2 19.4 11.4 11.7 12.3 14.0 14.0 10.7 12.0 13.3 13.3 16.7 10.6 9.9 18.4 22.3 26.7 10.8 14.3 11.4 12.8 7.9 7.0 8.7 11.8 7.4 7.5 2.1 3.7 3.6 17.8 0.0 8.0 11.5 4.2 8.3 5.5 6.1 7.2 3.1 6.6 11.1 3.6 6.2 8.1 5.1 5.1 7.2 5.6 4.9 8.7 17.4 6.6 5.1 10.1 5.3 12.9 4.8 7.1 4.3 5.9 8.5 22.9 8.4 3.6 6.2 7.3 2.6 4.3 4.9 12.6 5.8 5.7 9.3 7.4 9.5 9.7 12.3 2.6 21.0 6.3 7.1 9.1 7.6 6.9 6.1 12.6 7.5 7.0 6.2 7.9 5.2 8.7 4.4 8.1 5.0 5.9 5.8 7.0 7.5 4.4 4.7 7.9 7.5 6.2 4.3 7.4 11.8 7.0 4.4 2.1 13.0 20.1 31.9 25.9 13.5 22.4 18.5 19.3 25.2 18.4 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 40.4;RPMI-8226: 18.1;U-266/70: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.7 0.9 2.3 2.2 1.8 4.4 1.9 4.2 1.3 1.1 1.2 1.2 2.8 1.3 1.4 1.4 1.2 1.8 3.2 0.8 1.0 2.6 0.9 1.8 13.5 1.2 0.9 2.0 5.1 3.6 11.5 2.4 1.8 40.4 1.1 1.5 1.8 0.5 0.3 1.6 1.9 1.9 18.1 1.1 2.9 3.2 1.9 1.8 3.0 4.4 1.6 2.6 2.3 1.1 2.6 2.5 1.1 38.1 10.0 2.2 2.1 1.3 1.8 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 ERO1B "ERO1-L(beta), Ero1beta, ERO1LB" ENSG00000086619 "Endoplasmic reticulum oxidoreductase 1 beta" Q86YB8 1 236215555-236281985 "Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pancreas: 160.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028085 Enhanced "Intracellular and membrane" "HPA028085: AB_10601214" "unprognostic (1.16e-1)" "unprognostic (1.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-2)" "prognostic favourable (7.53e-5)" "unprognostic (1.73e-2)" "unprognostic (2.85e-2)" "unprognostic (4.65e-2)" "unprognostic (5.90e-2)" "unprognostic (8.26e-3)" "unprognostic (7.87e-2)" "unprognostic (3.37e-1)" "unprognostic (2.22e-3)" "unprognostic (8.09e-3)" 2.7 2.5 3.2 4.3 4.8 2.6 6.9 7.4 4.0 2.4 3.3 2.0 5.7 4.4 2.5 10.1 1.4 2.1 4.1 2.9 3.3 2.7 3.7 11.6 2.5 3.5 4.0 1.7 3.4 160.4 5.4 8.5 2.2 3.9 2.7 1.4 1.4 9.0 3.2 1.9 1.7 2.7 2.2 3.0 4.1 17.7 10.9 4.1 4.1 12.5 0.8 2.7 2.4 2.3 2.9 7.2 12.9 1.9 1.3 2.8 0.9 1.9 2.2 3.8 3.2 3.0 2.0 4.6 2.9 2.8 2.1 1.8 0.6 2.0 5.2 8.1 4.6 0.9 1.8 2.6 3.0 5.2 11.3 1.5 0.3 2.0 8.2 2.1 0.9 3.5 5.6 3.7 7.0 2.5 0.8 13.2 2.8 1.0 0.9 0.9 1.5 0.7 10.8 2.7 1.3 4.2 4.5 7.9 4.6 9.4 3.2 7.7 7.7 9.4 2.3 3.1 2.7 3.2 3.8 9.2 0.5 3.0 4.4 3.1 4.8 12.9 1.9 3.2 2.8 1.9 2.5 1.9 1.5 1.9 1.9 2.9 2.3 2.2 3.9 1.3 0.8 7.2 1.4 0.9 3.2 4.8 7.4 4.0 3.3 2.7 4.0 1.7 3.9 4.1 ERRFI1 "GENE-33, MIG-6, RALT" ENSG00000116285 "ERBB receptor feedback inhibitor 1" Q9UJM3 1 8004404-8026308 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 141.1;pancreas: 133.6" "Cell line enhanced" "Detected in many" "HHSteC: 93.0;LHCN-M2: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 4.9" "Group enriched" "Detected in many" 7 "monocytes: 4.9;T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027206, HPA076543" Enhanced Cytosol Cytosol "HPA027206: AB_10600908, HPA076543: " "unprognostic (2.13e-3)" "unprognostic (1.01e-2)" "unprognostic (2.34e-1)" "unprognostic (1.71e-2)" "unprognostic (2.50e-3)" "unprognostic (1.66e-3)" "unprognostic (2.27e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.47e-1)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (1.19e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (8.03e-3)" 38.6 8.8 4.4 6.3 6.3 0.6 27.8 9.6 7.0 17.5 13.6 5.4 8.4 6.8 15.9 9.6 13.6 12.2 27.3 8.8 4.7 2.5 32.6 141.1 15.5 7.7 7.5 3.7 29.7 133.6 7.7 41.9 33.7 8.1 9.3 5.1 12.0 14.5 5.9 68.3 20.2 26.5 22.9 12.5 2.1 22.3 7.4 5.2 0.6 19.4 4.7 3.8 20.0 19.5 0.4 0.3 0.2 4.9 0.0 1.3 0.2 13.2 7.8 3.3 4.5 32.0 23.9 35.1 13.0 3.8 2.4 2.8 3.4 35.0 0.2 7.8 4.3 2.8 0.9 23.0 11.2 0.4 2.5 0.2 2.3 40.4 93.0 0.1 0.5 32.5 23.2 8.0 19.5 6.1 0.9 0.1 71.0 5.7 0.0 0.8 8.0 19.5 1.1 37.9 0.2 11.2 4.2 2.3 1.3 2.5 5.9 4.0 4.0 0.3 8.6 9.4 5.5 7.9 18.3 0.2 0.1 0.2 36.4 0.6 8.7 0.0 0.4 0.0 1.3 0.1 0.2 0.3 1.2 1.3 0.2 0.4 0.9 1.2 0.2 0.0 4.9 0.3 0.6 0.2 4.4 6.3 9.6 7.0 4.7 2.5 7.5 3.7 8.1 5.2 ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305572-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 78.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053785 Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favourable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" 8.2 9.6 6.0 8.9 7.7 7.9 17.8 9.8 9.4 4.3 32.4 4.9 18.3 43.1 4.6 6.2 17.1 4.1 15.7 45.2 6.8 5.0 21.4 26.9 8.7 9.2 10.4 5.2 2.5 20.5 10.1 4.6 11.0 8.0 7.5 12.6 6.0 28.7 14.9 78.3 10.5 46.4 7.1 7.4 9.3 14.1 2.2 6.0 6.0 8.2 27.1 10.0 8.5 12.0 4.1 4.2 8.5 8.4 2.6 5.4 2.4 9.7 15.6 3.9 9.4 5.3 5.1 21.2 9.6 4.7 3.6 3.6 14.4 11.9 13.4 18.0 5.1 25.1 6.5 12.9 1.4 9.0 8.4 8.6 18.5 11.3 7.3 14.6 21.8 7.2 19.7 8.1 10.7 5.0 14.5 7.4 5.9 21.9 7.1 20.8 10.8 29.7 7.7 7.6 29.9 12.0 20.6 8.2 10.1 4.9 32.7 30.9 10.1 14.5 10.8 6.6 7.9 18.5 9.7 11.4 9.4 8.8 10.7 14.4 5.2 0.3 4.7 7.1 4.4 8.4 4.4 2.9 3.8 3.1 4.2 4.1 4.1 5.4 8.5 2.6 7.5 3.2 5.1 2.4 6.0 7.7 9.8 9.4 6.8 5.0 10.4 5.2 8.0 6.0 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365625-31376850 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 420.9;skeletal muscle: 129.4" "Cell line enriched" "Detected in some" 5 "ASC TERT1: 117.9" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" 4400000 "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: " "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favourable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 2.3 5.2 8.1 0.7 6.0 0.5 22.7 1.4 14.6 3.9 1.3 0.8 3.4 0.7 6.8 5.3 3.1 2.8 1.1 420.9 11.0 5.3 21.3 1.9 4.3 1.3 9.8 6.0 2.2 0.4 0.3 0.7 1.1 13.7 5.0 1.5 3.0 4.4 14.0 129.4 0.9 0.6 13.0 3.4 3.9 3.6 2.0 1.3 0.1 1.7 31.6 2.2 2.5 2.5 1.4 0.5 0.0 0.9 0.2 0.9 0.6 0.1 0.0 3.2 0.2 22.6 117.9 1.1 0.9 8.7 0.1 3.1 0.2 0.8 0.2 12.5 2.4 0.3 0.9 0.0 0.1 0.1 0.5 0.3 1.1 2.3 1.5 0.2 0.0 10.4 0.0 2.3 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.2 6.0 0.4 0.1 1.2 0.0 2.8 0.0 0.3 0.0 0.5 0.0 13.5 0.1 1.4 0.3 0.2 0.1 2.1 0.1 0.1 0.4 0.1 0.5 0.1 0.2 0.0 0.4 0.0 0.9 0.9 0.6 0.2 0.5 0.5 0.5 1.4 0.0 0.9 0.0 0.2 0.1 0.4 0.6 0.6 8.1 6.0 1.4 13.3 11.0 5.3 9.8 6.0 13.7 1.3 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799625-61829318 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 97.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavourable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavourable (2.79e-4)" "prognostic unfavourable (1.33e-4)" 15.1 51.6 26.7 14.4 21.8 6.6 7.6 12.5 41.4 9.6 4.8 46.1 12.9 4.6 14.8 5.6 4.6 8.5 11.1 16.6 23.2 21.8 6.5 38.3 14.9 11.5 16.2 25.4 23.2 7.8 34.4 11.3 15.3 27.1 15.2 4.3 23.0 4.9 13.5 8.9 7.7 3.8 15.4 18.6 6.1 5.7 9.0 21.8 3.3 4.5 1.9 6.9 8.7 7.8 4.2 14.9 3.8 21.1 3.6 6.6 7.3 11.6 30.6 29.2 7.3 57.6 97.6 8.5 7.4 36.0 12.8 21.4 9.3 26.0 0.4 8.1 10.9 15.3 23.4 20.6 9.5 2.1 3.3 18.4 35.2 16.8 31.0 4.0 1.9 43.8 6.8 28.5 13.9 11.4 10.1 21.7 12.6 3.2 13.7 4.0 16.9 11.3 15.1 28.9 40.6 14.7 5.2 14.9 16.4 18.6 0.3 16.2 6.9 17.7 10.7 13.3 13.5 13.3 8.9 20.8 18.8 9.4 7.8 18.9 10.8 3.8 18.0 3.2 6.6 21.1 1.4 1.3 2.3 2.7 14.9 4.2 1.3 3.2 1.4 3.6 8.9 12.5 1.4 7.3 26.7 21.8 12.5 25.5 23.2 21.8 16.2 25.4 27.1 21.8 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "Family with sequence similarity 3 member B" P58499 21 41304212-41357431 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.8;pancreas: 120.3;salivary gland: 67.9" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;CAPAN-2: 5.9;Hep G2: 15.2;RPMI-8226: 42.1" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "eosinophil: 3.0;neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777" Approved Approved Vesicles "Secreted to blood" 2075500 57000 Vesicles "HPA015885: AB_1848396, HPA029777: " "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 0.6 0.2 0.2 4.5 0.4 0.0 4.3 0.2 0.3 1.8 38.5 0.4 29.9 38.2 0.2 8.8 17.4 4.5 6.9 0.4 0.2 0.2 5.2 0.6 2.0 0.7 0.3 0.2 0.7 120.3 0.0 1.9 7.9 0.4 10.0 0.0 0.2 67.9 36.0 0.2 0.9 83.8 2.0 0.3 0.5 30.8 2.0 0.2 2.3 3.9 7.4 17.6 17.5 4.7 0.2 1.3 6.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 42.1 0.0 2.8 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 6.9 0.0 0.6 1.3 0.0 0.0 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.2 0.4 0.2 FAM3D "EF7, OIT1" ENSG00000198643 "Family with sequence similarity 3 member D" Q96BQ1 3 58633946-58666848 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 61.2;intestine: 69.2;salivary gland: 146.0;seminal vesicle: 88.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.4;RT4: 2.8;T-47d: 2.3;U-266/70: 1.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 151.0" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "neutrophil: 6.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA013844 Approved "Secreted to digestive system" 8200 "HPA013844: " "prognostic favourable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favourable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" 0.3 0.2 0.3 8.5 0.3 0.0 2.2 0.2 0.2 4.4 48.2 0.3 26.1 11.2 0.5 0.3 61.2 0.3 20.0 0.2 0.2 0.2 0.5 0.2 1.5 0.2 0.3 0.2 0.2 0.8 0.0 0.3 0.5 0.3 3.3 69.2 0.3 146.0 88.6 0.4 0.8 26.1 0.8 0.2 0.3 9.5 0.3 0.2 0.3 0.6 15.2 47.1 2.2 13.1 0.0 0.7 6.7 1.6 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 0.0 0.0 3.4 0.3 0.0 0.0 1.3 0.3 1.4 0.7 0.0 0.3 0.5 1.0 0.1 2.8 0.2 1.3 0.0 0.0 0.0 2.3 0.0 0.5 0.1 0.7 0.9 0.6 1.8 1.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.5 0.0 0.0 0.9 0.3 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.3 0.2 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 76.1" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.5;Hep G2: 4.4;NTERA-2: 1.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035132 Supported "Secreted to blood" 47505000000 4500000000 "HPA035132: AB_10601650" "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 2.6 11.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.5 0.0 0.9 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.2 0.6 0.4 0.2 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360485 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;blood: 5.6;lymphoid tissue: 6.1" "Group enriched" "Detected in some" 5 "ASC diff: 1.1;HHSteC: 3.8;HSkMC: 3.3;U-937: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "eosinophil: 4.7;neutrophil: 5.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.6" HPA044681 Uncertain "HPA044681: " "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" 6.5 0.0 0.1 6.1 0.3 1.7 3.8 0.0 0.2 0.0 2.1 0.7 0.0 0.0 0.0 0.5 1.1 0.2 0.4 0.2 0.0 0.5 0.6 0.4 0.5 0.3 1.0 0.4 0.5 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.9 3.7 1.5 2.4 1.3 0.0 0.9 0.0 0.7 0.0 0.0 0.1 5.6 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.4 0.0 0.1 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.3 0.0 0.0 0.2 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 15.8;lung: 11.7;pituitary gland: 39.2" "Cell line enhanced" "Detected in some" "A549: 3.3;CACO-2: 2.7;HaCaT: 5.5;NB-4: 6.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042563 Uncertain "Plasma membrane" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 5.2 0.6 1.8 2.8 1.7 0.2 1.9 0.1 2.6 0.2 11.3 1.1 0.0 0.7 0.1 0.1 0.4 1.4 2.6 1.2 0.9 1.6 0.3 0.6 11.7 1.3 0.6 1.0 0.3 1.1 0.1 39.2 0.4 0.8 0.2 15.8 0.3 0.9 0.1 0.5 1.3 1.0 0.3 2.6 0.2 0.7 2.0 0.9 0.7 0.2 0.0 0.6 0.3 0.2 0.5 3.4 1.3 3.0 0.7 0.3 0.8 0.1 3.3 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 2.7 0.8 0.2 0.5 0.0 5.5 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.1 0.3 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.1 0.1 0.1 0.0 1.1 0.2 0.3 0.1 0.2 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.9 3.0 0.2 0.3 0.6 0.2 0.4 0.2 0.2 3.4 0.5 0.2 0.3 1.3 0.7 0.4 0.4 0.1 0.8 1.8 1.7 0.1 2.6 0.9 1.6 0.6 1.0 0.8 0.9 FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22581005-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.4;pancreas: 47.9;stomach 1: 20.7" "Cell line enhanced" "Detected in some" "A549: 10.2;HBEC3-KT: 11.7;Hep G2: 16.2;hTERT-HME1: 7.9;PC-3: 15.1;SCLC-21H: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Region enriched" "Detected in single" 7 "midbrain: 4.9" "CAB001388, HPA066846" Enhanced Supported "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "CAB001388: AB_2262810, HPA066846: " "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "prognostic favourable (7.57e-6)" "unprognostic (6.82e-2)" "unprognostic (1.50e-6)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "prognostic favourable (6.28e-4)" "prognostic favourable (2.34e-4)" "unprognostic (3.18e-1)" "unprognostic (2.55e-15)" "unprognostic (2.50e-2)" "unprognostic (1.68e-1)" "unprognostic (7.12e-2)" "unprognostic (3.93e-3)" 0.2 0.0 0.2 1.3 0.2 0.0 0.2 0.2 0.3 9.7 4.5 0.2 0.2 2.2 1.8 0.2 0.2 3.8 13.1 0.2 0.2 0.1 0.2 44.4 15.9 0.2 1.4 0.2 3.4 47.9 0.0 0.4 0.3 0.4 0.5 6.0 0.2 0.2 0.2 0.2 0.0 1.8 0.2 0.2 0.2 20.7 0.3 0.2 0.2 2.2 0.2 0.9 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.1 0.0 0.0 0.0 11.7 0.0 0.0 0.7 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.3 0.0 7.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.5 0.0 26.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.1 1.4 0.2 0.4 0.2 FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86567251-86569728 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.6" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 15.7;HUVEC TERT2: 12.0;LHCN-M2: 19.3;TIME: 21.4;U-138 MG: 11.5;U-2197: 19.3;U-87 MG: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA056302 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA056302: " "unprognostic (3.17e-2)" "unprognostic (1.76e-3)" "unprognostic (4.87e-2)" "unprognostic (4.32e-1)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (4.49e-2)" "unprognostic (1.15e-2)" "unprognostic (4.71e-2)" "unprognostic (8.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "prognostic unfavourable (3.57e-7)" "unprognostic (1.12e-2)" "unprognostic (3.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.84e-4)" 4.8 5.7 1.1 1.6 1.4 0.5 6.4 1.1 3.4 6.2 2.0 2.2 0.1 1.1 1.6 5.3 3.0 3.9 5.6 8.8 1.1 1.1 9.1 0.9 4.9 5.4 4.3 2.6 4.0 1.3 0.6 3.7 0.9 9.9 2.1 1.0 17.6 4.2 2.9 3.2 1.5 0.9 2.1 8.5 0.5 1.1 7.7 0.7 0.0 3.3 1.0 0.9 4.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.0 0.0 6.4 8.8 5.0 0.9 0.0 0.0 0.0 0.9 0.8 0.0 0.1 2.0 4.4 0.0 0.3 0.0 4.8 0.0 1.7 0.0 0.0 0.8 2.1 15.7 5.0 12.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.4 11.5 0.0 19.3 0.0 0.0 0.0 0.0 15.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 1.1 3.4 1.1 1.1 4.3 2.6 9.9 0.7 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71096197-71103535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 98.6" "Cell line enriched" "Detected in many" 5 "BEWO: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA039560: , HPA040232: " "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favourable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favourable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 8.5 13.2 21.7 3.8 21.5 9.9 5.1 9.1 15.6 4.8 8.4 9.1 11.9 6.3 6.8 10.2 7.3 7.7 5.8 9.7 21.4 14.5 5.2 3.6 5.5 3.6 22.8 8.4 13.4 6.8 8.7 3.0 98.6 9.2 7.0 4.7 4.9 8.5 11.3 33.8 5.5 6.6 9.4 17.3 6.0 5.2 13.9 13.1 4.4 5.9 7.5 4.2 7.5 11.0 0.9 0.2 3.4 0.6 1.0 1.8 0.9 1.7 0.5 1.4 1.8 3.3 2.3 60.0 1.4 1.6 0.7 1.7 1.2 2.4 2.3 1.8 1.8 0.8 3.6 1.6 0.8 2.3 5.5 3.4 11.2 1.9 1.9 1.9 2.7 1.9 3.8 0.6 0.4 1.8 6.9 4.6 0.3 0.3 3.0 3.1 6.5 2.1 2.1 3.5 3.6 1.2 1.0 1.0 2.9 2.9 0.4 3.1 0.7 1.2 1.7 0.4 0.9 3.1 0.3 3.0 1.6 0.4 1.6 5.2 0.5 0.2 0.6 3.2 0.9 0.6 0.3 0.8 0.5 0.9 0.2 0.9 0.4 1.8 3.4 1.0 0.3 0.0 1.3 0.9 21.7 21.5 9.1 15.6 21.4 14.5 22.8 8.4 9.2 13.1 G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901240-168910000 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "pancreas: 28.8;retina: 12.1" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.1" "Cancer enriched" "Detected in single" 92 "pancreatic cancer: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "unprognostic (6.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.04e-2)" "unprognostic (9.05e-2)" "unprognostic (2.97e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-2)" "unprognostic (1.87e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 GAB1 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.0" "Cell line enhanced" "Detected in many" "REH: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Nucleoli fibrillar center" "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favourable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 9.2 8.4 15.0 7.3 33.3 8.8 9.7 5.8 22.0 10.1 17.0 64.0 10.2 10.4 17.7 13.1 18.2 8.6 11.1 26.2 19.5 11.4 12.9 7.9 15.6 5.0 35.7 19.0 18.1 7.0 17.2 6.3 18.0 30.5 7.8 20.3 15.4 11.7 13.9 11.2 11.1 10.4 15.9 32.3 6.2 11.0 7.9 41.7 1.0 7.8 6.0 7.3 9.9 11.9 3.1 3.4 5.9 2.3 7.4 0.4 0.4 3.3 0.7 8.7 6.3 4.4 4.3 11.4 2.3 7.8 2.8 5.0 6.5 5.7 0.1 0.7 3.3 1.9 8.3 2.7 3.2 0.4 2.0 6.1 1.9 3.0 3.0 0.8 1.2 5.2 4.9 3.4 2.3 3.7 2.0 11.2 1.9 4.9 0.5 0.0 2.5 2.7 37.3 4.3 4.3 4.4 4.1 2.0 6.2 1.6 6.8 2.9 4.4 0.8 2.8 3.6 2.9 1.7 1.7 18.1 8.8 13.4 2.4 2.4 2.9 5.9 0.6 0.7 0.0 0.8 0.4 1.3 0.1 0.0 0.8 3.1 0.0 0.0 4.0 7.4 2.3 3.4 0.0 0.4 15.0 33.3 5.8 22.0 19.5 11.4 35.7 19.0 30.5 41.7 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 53.9" "Cell line enhanced" "Detected in many" "HaCaT: 10.5;HEL: 34.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "olfactory region: 888.9" "CAB004415, HPA031949, HPA058412, CAB078176" Enhanced Supported Approved Vesicles Vesicles "CAB004415: AB_627650, CAB078176: , HPA031949: , HPA058412: " "unprognostic (1.28e-1)" "prognostic favourable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favourable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 1.2 2.0 14.5 0.9 28.1 3.7 1.0 10.6 53.9 1.8 1.0 3.1 0.0 1.0 2.6 5.5 1.2 1.1 1.0 1.0 10.8 24.4 6.0 1.0 1.1 1.1 8.6 17.5 1.1 1.1 9.5 2.8 1.4 6.0 1.8 1.0 1.3 1.0 1.3 0.9 1.0 1.1 1.0 2.6 1.0 1.0 4.0 3.4 0.0 1.1 0.0 1.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.3 0.0 3.7 0.0 0.0 0.0 0.2 0.0 1.4 0.9 2.5 3.5 0.0 0.5 0.2 10.5 1.2 0.3 0.8 1.4 7.2 34.2 3.0 0.1 0.0 0.1 0.6 0.0 3.1 0.0 1.2 0.0 8.8 0.1 0.4 0.8 0.0 0.0 4.2 3.7 0.5 2.5 0.2 4.6 4.9 3.6 1.1 6.5 0.0 1.8 0.1 0.0 0.0 6.4 0.9 1.3 3.7 0.0 0.0 0.0 6.2 1.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 28.1 10.6 36.7 10.8 24.4 8.6 17.5 6.0 3.4 GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216307-26304558 "Enzymes, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 66.2" "Group enriched" "Detected in some" 12 "MOLT-4: 5.0;SCLC-21H: 11.4" "Group enriched" "Detected in some" 21 "glioma: 0.7;pancreatic cancer: 3.0;testis cancer: 1.2" "Region enhanced" "Detected in all" "basal ganglia: 66.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced "CAB078177: , HPA044637: AB_10794053" "unprognostic (8.67e-2)" "unprognostic (1.11e-1)" "unprognostic (4.93e-2)" "unprognostic (2.52e-5)" "unprognostic (5.44e-2)" "unprognostic (8.08e-2)" 1.0 0.9 6.3 0.9 66.2 1.0 0.9 5.6 28.7 0.9 0.9 1.4 0.0 1.2 0.9 1.1 0.9 0.9 0.9 0.9 5.2 13.2 1.0 0.9 0.9 0.9 5.4 10.0 0.9 12.9 0.9 0.4 0.9 6.8 1.2 1.0 0.0 0.9 0.9 0.9 1.3 1.1 0.9 1.3 0.9 1.2 1.7 8.1 0.0 0.9 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 66.2 5.6 18.2 5.2 13.2 5.4 10.0 6.8 8.1 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574587 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 28.7;gallbladder: 13.4;intestine: 25.1;kidney: 13.3;stomach 1: 7.2" "Cell line enhanced" "Detected in some" "A549: 22.6;CACO-2: 6.2;EFO-21: 12.3;K-562: 5.2" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001220 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA001220: AB_1078933" "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 0.8 0.6 8.4 0.7 9.6 1.2 0.8 1.4 12.3 1.4 11.3 25.8 0.0 24.2 1.3 2.3 0.8 2.2 13.4 0.5 12.1 8.3 13.3 1.6 1.5 0.9 14.0 2.6 1.2 2.9 0.6 0.5 1.3 12.4 1.2 2.8 0.3 1.0 1.9 1.9 2.1 25.1 0.7 28.7 0.7 7.2 2.5 7.8 0.0 0.6 0.0 0.4 1.0 0.7 2.3 2.8 2.3 0.7 0.3 0.8 0.0 0.1 22.6 0.4 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.2 3.1 0.3 12.3 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.3 0.2 4.1 0.5 0.1 0.3 0.2 0.0 0.1 0.1 0.0 5.2 0.6 0.0 0.1 0.3 0.8 3.2 0.3 0.2 0.1 0.6 0.9 0.1 0.3 1.5 0.0 0.4 0.2 0.1 0.1 0.6 0.2 0.1 0.2 0.0 2.0 1.2 0.3 0.1 0.1 0.2 0.9 0.7 0.1 0.4 0.5 0.7 1.8 0.7 0.8 0.2 2.3 0.5 0.8 2.3 0.3 0.3 2.8 0.1 0.0 8.4 9.6 1.4 10.3 12.1 8.3 14.0 2.6 12.4 7.8 GALP ENSG00000197487 "Galanin like peptide" Q9UBC7 19 56176020-56185775 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Hormone, Neuropeptide" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "brain: 4.4;liver: 4.1" "Cell line enhanced" "Detected in some" "Daudi: 1.1;EFO-21: 1.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Region enhanced" "Detected in many" "pons and medulla: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hippocampal formation: 29.0" HPA053938 Uncertain "Secreted in brain" "HPA053938: " "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (7.02e-2)" 0.0 0.2 1.2 0.0 1.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 0.0 0.1 1.1 0.7 0.4 0.0 4.4 0.0 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell line enhanced" "Detected in all" "A549: 54.7;Hep G2: 46.7;RT4: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 8.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol 3600000 Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favourable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavourable (8.24e-4)" "unprognostic (2.30e-2)" 15.8 11.1 12.9 9.0 16.0 14.4 13.0 5.4 15.1 6.8 16.2 21.6 8.2 18.9 9.2 5.3 20.0 29.1 14.9 7.4 13.1 10.6 15.4 69.2 12.9 10.1 21.6 12.2 6.2 12.4 6.6 5.4 6.2 13.0 13.0 12.2 5.2 11.2 10.1 7.0 8.6 14.8 11.9 13.6 16.8 14.8 5.2 17.5 3.1 14.1 32.4 10.6 34.4 12.3 1.6 4.2 2.2 1.9 8.0 2.3 0.6 8.1 54.7 4.5 10.6 5.4 2.4 6.0 4.1 6.7 3.1 3.7 8.0 19.0 15.5 7.9 3.7 11.6 13.7 30.1 4.2 12.2 8.4 10.4 10.6 46.7 6.2 13.6 6.4 3.8 12.8 3.5 15.7 4.7 5.7 4.9 1.5 8.6 11.7 5.4 8.3 5.1 3.9 2.7 13.7 10.1 50.4 13.0 6.4 6.9 11.1 7.2 7.6 6.5 6.5 2.8 9.8 7.1 6.1 6.6 10.1 9.0 7.0 9.8 4.7 2.2 1.1 0.6 1.2 1.9 0.8 1.6 1.0 2.3 4.2 1.0 0.6 1.3 0.5 8.0 1.8 3.0 1.6 0.6 12.9 16.0 5.4 11.9 13.1 10.6 21.6 12.2 13.0 17.5 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1, core 2" Q02742 9 76419850-76507416 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.0;parathyroid gland: 57.8" "Cell line enhanced" "Detected in many" "HHSteC: 25.8;HSkMC: 21.9;U-2197: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 16.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "cerebellum: 8.2;olfactory region: 30.1" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" 72000 "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favourable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavourable (4.96e-4)" 5.6 1.1 1.6 7.9 3.9 2.2 8.2 10.9 2.7 5.3 24.5 0.7 3.0 23.2 5.2 1.2 2.1 1.8 4.1 3.1 2.1 1.4 1.4 1.0 4.5 9.2 1.6 2.1 0.9 2.0 57.8 1.9 3.9 1.0 4.9 4.6 0.5 9.1 1.8 0.8 1.5 32.0 2.5 1.2 7.6 18.6 1.4 0.6 2.8 16.9 1.2 6.4 2.4 3.3 9.4 4.7 16.8 6.4 4.7 1.9 1.6 2.4 0.2 0.1 0.0 3.1 14.9 3.6 10.0 4.5 8.1 5.8 2.5 0.6 1.7 1.0 7.4 2.1 5.0 4.1 9.1 1.2 0.8 4.2 0.2 0.4 25.8 3.1 1.4 21.9 1.1 7.9 8.5 7.4 0.0 1.7 8.1 3.7 1.6 5.0 4.7 0.6 2.8 5.0 0.8 9.5 4.4 1.0 0.0 1.2 1.3 0.0 0.0 2.1 3.0 5.1 3.3 18.3 4.4 2.6 0.4 0.0 10.3 5.3 1.2 4.3 2.7 16.8 1.3 6.4 0.4 1.3 1.5 1.3 4.7 9.4 0.2 1.0 0.9 4.7 5.7 2.3 1.9 1.6 1.6 3.9 10.9 2.7 2.1 1.4 1.6 2.1 1.0 0.6 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63015079-63039171 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.5;liver: 59.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in all" 4 "dendritic cells: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" 1400000000 "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavourable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 3.5 3.6 7.4 4.7 8.6 12.3 11.8 15.5 9.9 3.5 17.6 1.5 1.0 3.7 2.6 3.7 11.0 1.6 2.8 5.9 7.9 7.6 42.5 59.5 3.5 5.0 4.7 7.0 1.9 4.2 1.0 1.6 17.7 14.8 1.9 26.4 2.2 6.5 1.8 1.7 11.1 3.6 4.2 7.6 3.7 3.2 14.0 3.8 5.2 1.4 14.5 7.6 3.9 6.6 4.1 18.2 2.1 1.9 2.9 1.4 1.4 20.4 19.7 20.2 3.1 19.9 8.4 14.9 12.6 21.6 20.0 29.1 27.5 36.3 14.0 3.6 15.6 17.1 20.0 21.1 29.8 28.4 15.1 23.0 10.6 18.6 3.8 10.7 13.8 6.1 6.0 20.2 9.7 24.2 12.2 51.3 37.5 11.6 5.2 10.7 9.5 18.6 15.6 19.7 18.8 15.5 7.2 8.1 13.8 18.4 20.1 19.1 22.2 11.9 12.8 21.6 24.2 20.7 22.7 24.0 24.4 16.4 33.4 0.0 38.1 0.0 1.9 2.1 1.1 1.1 0.5 4.1 1.3 1.3 0.6 1.9 1.0 1.3 1.8 2.9 1.2 18.2 1.4 1.4 7.4 8.6 15.5 9.9 7.9 7.6 4.7 7.0 14.8 3.8 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435692-121449727 "Cancer-related genes, Disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease mutation, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 48.8;HUVEC TERT2: 61.6;NTERA-2: 62.7;TIME: 45.3;U-87 MG: 61.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: , HPA047551: , HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavourable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 19.7 65.2 78.6 5.5 69.7 0.4 14.2 32.4 44.4 64.5 4.0 23.8 6.1 4.2 23.5 5.5 17.3 7.8 23.0 36.0 87.3 25.5 3.6 2.5 15.2 4.4 42.9 39.9 10.5 4.5 94.7 5.7 63.8 53.7 20.0 4.8 26.3 7.1 35.7 3.4 86.3 4.4 25.6 38.7 1.1 6.4 8.3 64.3 0.5 38.9 9.9 7.6 14.8 32.2 0.5 0.5 0.4 0.5 0.0 0.4 0.0 0.0 7.2 32.1 0.0 17.5 10.9 0.0 24.0 48.8 8.1 19.8 0.1 0.0 0.0 2.7 9.3 3.1 0.8 14.7 26.4 0.0 8.8 0.3 2.9 0.0 21.9 0.0 0.0 29.0 15.9 29.6 10.7 61.6 0.0 0.7 1.6 1.3 0.0 12.9 62.7 8.0 0.0 0.0 0.6 32.4 3.5 0.0 0.5 0.0 0.0 0.0 2.5 0.0 45.3 25.0 6.9 21.1 15.5 0.0 0.0 0.0 61.0 0.0 3.5 0.4 0.5 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.5 0.4 0.4 0.0 0.0 0.1 0.5 0.1 0.0 78.6 69.7 32.4 42.8 87.3 25.5 42.9 39.9 53.7 64.3 GJD2 "CX36, GJA9" ENSG00000159248 "Gap junction protein delta 2" Q9UKL4 15 34751032-34754965 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 13.8;pancreas: 8.7;pituitary gland: 23.9;retina: 9.1" "Cell line enhanced" "Detected in some" "NTERA-2: 2.3;SCLC-21H: 3.0" "Cancer enriched" "Detected in single" 32 "pancreatic cancer: 4.2" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "unprognostic (4.30e-2)" "unprognostic (2.87e-2)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" 0.3 13.8 1.3 0.3 2.1 0.3 0.2 1.4 4.5 0.4 0.3 0.1 0.0 0.2 0.4 0.2 0.2 0.2 0.3 7.0 1.1 1.6 0.9 0.2 0.3 0.2 0.8 2.8 0.2 8.7 0.2 23.9 0.3 3.4 0.2 0.3 9.1 0.2 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.4 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.5 0.6 2.1 1.1 1.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.8 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.4 0.8 0.5 0.6 0.7 0.5 0.5 0.3 0.5 0.5 0.6 0.6 2.1 1.0 1.1 0.6 0.5 0.4 1.3 2.1 1.4 4.5 1.1 1.6 0.8 2.8 3.4 0.0 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182381704-182392206 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 138.5;ASC TERT1: 97.9;HSkMC: 84.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 92.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 92.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported Mitochondria,Cytosol 28000 "Mitochondria, Cytosol" "CAB008636: AB_1616669, HPA007316: AB_1078981, HPA007571: AB_1078980" "prognostic favourable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 173.3 19.2 83.7 37.2 91.0 47.6 63.1 48.5 80.7 41.9 20.4 49.9 9.4 6.2 20.5 29.7 54.0 31.6 26.2 23.5 74.0 48.7 15.6 64.9 39.5 36.9 71.0 48.8 66.2 49.0 7.4 8.9 41.8 70.6 17.4 23.3 39.3 30.4 25.5 159.8 27.9 16.4 30.5 51.3 36.1 71.4 24.0 55.2 8.6 63.9 15.5 24.2 34.7 32.2 2.5 11.0 92.2 21.1 3.4 6.3 18.6 2.9 1.2 13.7 0.0 138.5 97.9 10.1 5.0 16.2 3.0 2.7 7.2 3.0 2.5 5.4 9.7 6.8 5.9 35.6 2.5 6.8 16.6 33.5 5.7 14.0 7.3 14.7 26.8 84.6 42.8 3.8 45.4 6.1 28.2 1.5 10.7 1.6 22.9 14.1 10.1 6.4 8.3 3.6 4.3 5.3 13.0 9.4 6.2 1.4 18.3 1.9 17.8 18.7 4.5 0.1 0.2 0.0 1.1 0.5 0.3 0.0 2.6 8.4 0.5 43.6 21.1 54.9 6.3 20.5 2.6 1.6 4.5 5.2 11.0 2.5 2.3 3.9 92.2 3.4 17.1 6.1 1.7 18.6 83.7 91.0 48.5 80.7 74.0 48.7 71.0 48.8 70.6 55.2 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 116.9;liver: 82.9;skeletal muscle: 102.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol 130000000 Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favourable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favourable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 3.3 14.0 15.7 3.6 32.1 2.0 5.9 22.9 56.4 13.5 12.0 9.7 5.9 14.7 3.4 7.0 10.3 4.6 12.2 116.9 19.4 19.0 34.6 82.9 3.5 3.4 17.8 16.4 3.8 8.2 15.9 4.9 3.7 49.9 5.9 14.7 9.0 12.4 7.2 102.1 4.5 12.7 5.4 7.7 3.6 10.1 9.3 4.7 3.3 11.7 31.3 7.1 4.9 4.0 10.6 21.4 3.9 16.8 11.4 15.6 8.8 16.9 9.4 11.1 28.0 8.6 7.4 31.4 13.9 25.6 24.3 26.5 21.3 13.8 16.6 4.8 11.7 21.3 25.3 18.3 26.8 5.7 10.8 6.3 12.1 27.7 45.6 18.0 10.8 11.6 19.8 20.6 55.9 11.7 16.2 26.0 15.5 15.3 9.6 13.5 7.1 13.1 10.5 10.6 17.3 42.4 9.3 4.8 7.1 10.5 14.9 51.9 28.5 6.2 5.4 6.2 13.8 6.7 15.9 18.6 21.9 16.9 16.3 9.4 8.2 2.4 5.3 3.9 12.4 14.7 11.4 10.6 13.5 12.9 12.9 10.2 10.2 14.5 0.5 11.4 16.8 21.4 15.6 8.8 15.7 32.1 22.9 56.4 19.4 19.0 17.8 16.4 49.9 4.7 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 9.9;Daudi: 10.4;Hep G2: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.3;intermediate monocyte: 4.2;myeloid DC: 8.4" "Group enriched" "Detected in many" 18 "dendritic cells: 8.4;monocytes: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027052 Approved "HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favourable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 14.2 10.9 12.1 3.6 13.2 1.2 11.5 5.1 11.1 6.4 7.1 5.6 3.5 2.0 5.4 1.8 5.5 4.8 3.2 6.0 8.3 6.2 7.4 19.5 25.6 6.4 8.6 8.7 3.3 4.0 1.8 4.7 13.3 6.1 6.8 3.7 5.2 4.2 11.8 8.6 2.8 2.6 5.5 4.1 6.5 23.9 2.2 8.6 1.3 16.5 2.3 2.8 6.4 7.2 0.3 8.4 0.0 4.3 0.0 0.0 1.6 0.9 0.3 0.2 9.9 2.4 2.4 1.0 5.7 3.8 1.8 3.3 0.2 0.2 10.4 0.9 7.1 0.5 0.1 0.0 0.2 2.1 1.8 0.0 1.2 19.0 0.3 0.1 0.6 1.3 0.0 1.1 0.0 0.5 0.1 0.1 0.4 0.6 0.0 0.3 1.9 6.8 0.9 0.0 0.0 0.2 0.0 0.1 3.9 0.0 0.4 2.1 0.2 0.1 1.4 0.4 2.6 6.0 1.8 0.0 0.0 3.6 3.3 0.1 0.2 0.0 4.3 0.0 0.0 4.2 0.0 0.3 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.6 12.1 13.2 5.1 11.1 8.3 6.2 8.6 8.7 6.1 8.6 GPR21 ENSG00000188394 "G protein-coupled receptor 21" Q99679 9 123034527-123035696 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 4.6" "Cell line enriched" "Detected in some" 8 "HBEC3-KT: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041651 Uncertain "HPA041651: AB_10794673" "unprognostic (9.22e-3)" "unprognostic (1.46e-1)" 3.6 0.0 1.1 1.7 2.2 0.2 1.1 0.1 4.6 2.1 0.4 0.0 2.7 1.0 1.9 0.9 0.8 0.5 0.7 0.4 0.3 0.0 0.5 1.9 0.3 1.4 0.0 0.2 0.0 1.5 0.1 0.6 0.1 0.7 0.4 0.6 0.3 1.7 0.4 0.9 0.5 0.0 1.0 0.9 1.3 2.0 0.9 0.0 0.1 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71754050-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 23.2;parathyroid gland: 29.6" "Cell line enhanced" "Detected in some" "EFO-21: 12.8;HL-60: 12.2;MCF7: 10.5;NTERA-2: 21.1;RPTEC TERT1: 10.1;SH-SY5Y: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "eosinophil: 3.7;neutrophil: 10.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favourable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favourable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.7 4.5 14.9 1.7 23.2 14.5 4.3 4.4 15.4 3.4 1.0 5.8 1.7 0.6 5.5 3.3 2.7 7.7 1.2 3.5 12.8 12.4 3.2 0.9 2.4 5.5 10.6 8.8 5.0 2.6 29.6 5.1 2.0 5.9 5.7 0.7 3.3 1.7 5.1 1.8 1.9 0.7 3.3 16.8 3.7 2.4 4.2 3.6 0.0 6.8 1.2 0.5 2.1 2.8 0.0 0.2 10.5 0.8 0.0 0.4 0.1 0.0 0.8 1.4 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 12.8 0.0 0.0 3.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 12.2 0.7 0.0 2.2 0.0 0.9 0.0 0.0 0.0 0.0 10.5 0.8 0.2 21.1 0.0 0.0 0.0 0.0 10.1 5.7 2.2 8.0 2.8 0.0 0.0 7.4 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 3.7 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 10.5 0.0 0.1 0.0 0.0 0.1 14.9 23.2 4.4 9.9 12.8 12.4 10.6 8.8 5.9 3.6 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.0" "Cell line enhanced" "Detected in many" "EFO-21: 38.4;HHSteC: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "naive CD4 T-cell: 6.5" "Lineage enriched" "Detected in many" 4 "T-cells: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavourable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 12.6 4.4 45.2 3.2 55.9 1.0 7.3 22.8 108.0 5.4 2.9 95.1 4.9 4.0 7.1 9.3 5.5 12.7 9.2 22.3 47.8 28.7 12.1 2.7 3.9 4.6 63.1 34.9 13.7 12.7 9.5 3.8 9.3 38.6 6.3 2.3 3.8 20.8 11.5 35.1 2.5 3.3 5.1 61.6 2.2 22.7 19.6 63.1 0.0 7.2 2.6 2.7 6.2 3.0 0.0 0.0 0.0 1.5 0.0 6.5 1.3 0.4 12.3 12.3 2.2 12.7 0.8 2.2 0.1 3.1 1.2 0.8 11.3 0.4 0.0 38.4 0.4 0.6 9.0 0.0 0.7 0.0 3.3 0.0 0.0 0.0 26.2 0.0 0.0 1.1 0.0 2.1 0.0 6.0 2.5 0.2 2.8 0.6 0.0 0.0 13.4 5.8 3.5 0.0 0.0 0.4 5.7 9.5 0.8 1.4 0.8 11.0 0.0 0.2 1.1 0.0 1.4 6.0 0.3 0.1 0.0 0.0 0.6 0.1 0.7 0.0 0.1 0.0 0.0 1.5 0.0 0.0 1.6 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 1.3 45.2 55.9 22.8 40.5 47.8 28.7 63.1 34.9 38.6 63.1 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583595-67586656 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 298.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol 120000000 "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 24.2 25.3 20.2 23.8 21.7 46.2 39.5 15.5 19.8 51.8 51.9 23.5 125.4 35.2 43.5 41.9 181.6 60.8 51.1 45.3 18.3 23.5 44.2 5.9 61.0 39.4 25.5 19.9 33.4 60.7 44.1 33.8 57.9 46.0 37.0 17.9 59.9 50.2 110.8 33.7 58.5 34.0 30.1 22.8 25.1 48.5 15.4 15.4 29.8 91.6 131.5 75.6 40.8 79.5 25.3 191.4 12.4 168.2 70.1 40.7 167.2 68.1 93.0 45.3 70.5 35.1 39.6 41.9 29.8 40.0 45.6 35.5 170.8 71.7 0.1 68.4 47.1 99.7 122.4 131.2 12.9 47.5 44.5 3.3 67.7 0.0 52.1 22.4 39.9 49.1 298.4 36.3 35.1 68.3 73.9 19.0 35.6 0.2 51.3 62.5 86.7 39.9 47.9 7.6 0.2 72.5 0.2 15.4 44.0 41.8 13.6 135.0 0.2 37.7 36.8 21.0 53.4 44.0 21.6 11.8 73.8 25.0 23.9 37.1 43.6 2.3 168.2 12.4 40.7 125.7 15.0 25.3 18.4 33.3 191.4 24.3 15.3 27.3 7.0 70.1 79.4 76.2 18.3 167.2 20.2 21.7 15.5 19.8 18.3 23.5 25.5 19.9 46.0 15.4 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244726 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria 2700000 Mitochondria "HPA015536: AB_1850473, HPA056070: " "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favourable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 41.6 35.3 18.1 13.1 19.5 17.0 23.9 17.4 16.9 20.2 44.9 26.5 15.7 48.1 21.1 15.3 30.8 20.5 15.1 80.0 15.6 15.5 41.3 71.7 17.7 19.3 21.6 13.1 27.3 37.5 29.8 23.5 21.3 24.8 21.9 32.2 23.6 21.1 16.6 117.5 23.3 66.4 25.1 27.8 24.0 24.1 18.7 19.0 25.2 25.1 41.3 24.6 26.9 18.8 15.3 28.9 12.4 32.2 13.5 17.6 26.0 23.3 20.8 13.7 22.4 54.5 34.1 11.7 18.3 19.8 18.9 16.4 26.3 22.7 15.4 12.0 32.1 14.9 24.0 35.5 17.1 34.5 29.4 23.1 22.1 43.8 18.8 29.1 17.0 34.8 23.3 26.8 26.9 31.6 31.4 31.3 24.3 28.6 12.7 32.6 11.7 40.2 11.7 29.6 33.1 21.6 28.2 9.7 19.3 21.5 22.4 24.8 11.9 28.2 28.9 11.0 16.3 16.4 13.4 10.3 20.3 27.4 17.1 34.5 13.2 8.1 27.7 12.4 12.3 32.2 14.8 15.3 14.2 15.0 28.9 11.2 16.7 15.3 7.4 13.5 28.0 11.0 17.6 26.0 18.1 19.5 17.4 16.9 15.6 15.5 21.6 13.1 24.8 19.0 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favourable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavourable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favourable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 15.6 17.6 24.9 7.9 15.8 13.2 18.1 35.9 25.8 16.5 8.8 19.6 9.5 8.4 15.0 11.9 20.1 16.9 11.3 24.4 22.1 24.2 8.6 6.3 13.6 8.8 24.7 22.1 24.5 16.1 28.2 17.5 23.0 19.3 13.6 5.5 11.7 14.2 11.9 42.6 34.0 9.7 12.4 20.5 13.8 9.3 10.3 18.1 7.6 15.0 9.8 8.2 14.9 20.4 7.6 9.4 17.9 13.6 3.5 4.9 5.0 3.5 2.3 6.4 1.5 12.4 9.7 23.1 9.6 24.0 4.8 7.9 5.1 3.8 5.6 3.9 22.8 2.9 7.5 4.1 2.0 8.7 12.2 10.9 7.7 11.7 5.3 3.5 15.4 13.7 7.1 5.5 6.9 3.9 8.1 11.4 27.8 2.7 5.8 10.7 7.0 5.5 22.5 17.9 14.4 0.5 1.6 16.7 8.8 2.8 11.8 13.0 16.8 20.7 2.1 12.1 7.8 2.8 4.8 18.8 15.7 6.7 7.0 4.4 5.7 7.1 7.3 7.7 4.9 11.6 3.5 6.6 3.9 4.9 9.4 7.6 4.1 3.5 17.9 3.5 13.6 8.3 3.5 5.0 24.9 15.8 35.9 25.8 22.1 24.2 24.7 22.1 19.3 18.1 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 54.3;hTERT-HME1: 26.0;SH-SY5Y: 21.7;U-698: 21.5;WM-115: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 29.5" "Group enriched" "Detected in many" 9 "B-cells: 21.8;dendritic cells: 29.5;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 10.7 13.5 12.6 10.7 16.2 5.9 8.4 19.1 16.9 11.6 7.4 11.3 7.5 3.8 17.8 6.7 4.7 10.5 7.5 14.9 13.1 12.0 3.9 3.1 5.7 18.9 13.9 14.9 3.0 2.7 3.0 17.7 6.8 11.2 12.5 6.2 9.7 6.9 16.5 15.5 3.8 8.4 14.4 17.6 17.4 9.1 8.7 18.2 2.9 5.5 5.4 19.3 7.1 9.6 21.8 29.5 0.5 9.7 2.0 2.1 4.5 12.3 0.0 2.0 0.0 0.3 2.8 0.0 0.7 7.3 3.1 5.3 0.1 4.0 5.3 13.7 8.2 1.8 54.3 1.0 8.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 1.0 1.0 9.6 26.0 0.1 0.0 8.3 4.2 0.0 0.5 1.0 6.6 1.2 1.5 0.8 3.1 1.7 3.3 3.9 21.7 0.1 0.1 3.9 0.2 4.9 0.5 11.3 3.6 0.6 7.0 9.6 4.1 21.5 2.9 0.5 22.2 0.1 9.7 0.0 1.7 6.7 1.7 21.8 0.6 0.8 29.5 16.3 0.0 0.9 0.5 2.0 3.8 6.4 2.1 4.5 12.6 16.2 19.1 16.9 13.1 12.0 13.9 14.9 11.2 18.2 HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 alpha subunit" Q16665 14 61695513-61748259 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 47.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Supported Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB017442: AB_10621732, HPA000907: , HPA001275: AB_1079057" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (9.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.77e-2)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (3.58e-1)" "unprognostic (7.35e-2)" "unprognostic (3.88e-2)" 31.9 62.0 15.6 45.2 17.8 125.2 24.9 22.7 18.5 45.7 15.3 12.3 23.5 10.8 17.7 31.3 31.2 21.7 50.0 19.4 17.5 16.5 76.4 42.7 42.8 27.3 18.3 11.0 34.5 12.7 13.7 26.8 24.2 25.1 17.6 13.9 14.0 24.6 36.2 8.0 17.4 16.9 18.7 27.2 57.3 16.0 21.1 12.4 24.7 26.9 18.4 28.8 37.8 21.5 6.6 6.0 47.8 6.8 6.2 7.9 5.1 37.6 15.0 15.1 43.2 24.0 38.7 20.5 31.3 37.8 39.5 35.6 6.5 12.5 9.2 23.6 38.7 8.9 9.7 51.5 49.4 4.0 5.0 5.6 13.8 11.2 53.6 2.3 6.2 67.6 16.3 28.9 31.0 24.8 3.8 0.0 117.8 7.8 7.3 2.9 13.6 19.8 0.5 34.0 2.7 50.9 25.1 12.7 14.1 58.8 8.4 20.7 8.8 4.5 14.7 89.7 20.1 29.7 26.3 4.9 7.2 10.4 47.3 4.7 24.2 11.2 6.8 47.8 3.8 5.5 4.9 6.5 5.0 4.4 6.0 6.6 7.9 5.1 18.2 6.2 5.6 2.9 3.4 5.1 15.6 17.8 22.7 13.2 17.5 16.5 18.3 11.0 25.1 12.4 HLA-DRB1 HLA-DR1B ENSG00000196126 "Major histocompatibility complex, class II, DR beta 1" "P04229, Q29974, Q9GIY3, P01911" 6 32578769-32589848 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 95.6;lung: 95.9" "Cell line enhanced" "Detected in some" "HDLM-2: 154.0;HMC-1: 21.9;U-266/70: 20.5;U-698: 26.5;U-87 MG: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 95.6" "Group enriched" "Detected in all" 10 "B-cells: 41.3;dendritic cells: 95.6;monocytes: 52.5" "CAB015400, CAB034021, HPA043151" Enhanced "CAB015400: AB_784538, CAB034021: AB_1124844, HPA043151: " "unprognostic (3.69e-3)" "unprognostic (3.66e-3)" "unprognostic (1.80e-2)" "unprognostic (2.40e-3)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (5.28e-2)" "unprognostic (1.22e-3)" "unprognostic (8.56e-2)" "unprognostic (3.00e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "unprognostic (2.28e-3)" "unprognostic (6.16e-2)" "unprognostic (1.19e-1)" "unprognostic (5.10e-2)" "unprognostic (1.53e-1)" 36.8 18.7 9.7 32.2 15.9 8.7 24.9 3.6 10.0 14.2 18.2 11.5 11.2 0.2 10.5 27.2 12.1 13.3 12.0 11.9 8.5 6.9 50.0 15.6 95.9 80.8 18.9 5.4 6.9 8.0 0.0 9.4 5.7 14.8 9.5 23.7 16.1 11.3 2.4 8.2 13.3 42.1 3.8 19.7 62.1 38.1 5.6 13.2 33.6 14.1 3.8 44.7 29.7 17.0 41.3 95.6 6.3 52.5 2.7 4.7 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.2 0.0 0.6 0.0 154.0 1.7 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.7 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.4 0.6 18.5 0.0 0.0 0.1 0.2 0.0 20.5 0.5 26.5 42.5 0.7 0.0 0.2 34.6 6.3 1.8 52.5 0.3 32.7 1.2 3.7 95.6 41.3 0.1 1.6 1.2 2.7 26.9 20.4 4.7 37.7 9.7 15.9 3.6 10.0 8.5 6.9 18.9 5.4 14.8 13.2 HMGCR ENSG00000113161 "3-hydroxy-3-methylglutaryl-CoA reductase" P04035 5 75336329-75362104 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008338, CAB016797" Approved "CAB016797: , HPA008338: AB_10960401" "unprognostic (5.07e-2)" "unprognostic (1.65e-2)" "unprognostic (3.65e-3)" "unprognostic (1.02e-2)" "unprognostic (1.65e-3)" "unprognostic (1.02e-1)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "unprognostic (1.90e-2)" "unprognostic (1.41e-1)" "unprognostic (3.99e-2)" "prognostic favourable (9.42e-6)" "unprognostic (2.44e-1)" "unprognostic (2.55e-2)" "unprognostic (3.64e-3)" "unprognostic (4.37e-2)" 5.6 28.9 12.4 8.7 31.1 12.1 16.4 14.4 36.3 13.9 23.0 10.9 7.1 18.9 9.0 14.4 35.0 6.5 8.2 4.0 21.8 16.5 12.1 53.5 12.1 7.0 9.8 19.4 15.2 8.4 16.2 11.4 9.2 29.6 12.4 19.7 7.8 12.4 4.5 3.4 36.1 19.0 6.8 17.0 7.9 14.6 14.0 8.8 13.9 12.5 23.2 12.4 6.2 18.1 4.3 12.5 23.2 11.0 9.5 6.5 5.1 15.8 6.3 63.7 21.9 13.5 26.1 16.0 4.6 12.8 9.4 20.9 23.5 39.2 14.2 16.7 7.4 20.1 33.0 53.7 9.9 4.8 12.1 10.8 9.5 18.1 19.9 9.0 8.0 16.9 31.6 32.6 16.2 7.5 11.6 21.8 14.7 10.4 16.6 9.1 27.2 4.7 11.7 19.0 20.3 38.5 37.2 22.1 10.0 10.1 10.5 9.1 10.3 23.8 8.7 5.1 7.6 5.4 7.8 7.0 8.8 19.6 7.4 17.7 10.5 6.7 11.0 6.3 6.1 6.9 5.1 4.3 4.6 6.4 12.5 4.2 4.5 6.2 23.2 9.5 7.4 3.9 6.5 5.1 12.4 31.1 14.4 36.3 21.8 16.5 9.8 19.4 29.6 8.8 HMGN3 TRIP7 ENSG00000118418 "High mobility group nucleosomal binding domain 3" Q15651 6 79201245-79234738 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018370, HPA027971, HPA063572" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB018370: , HPA027971: AB_1850808, HPA063572: " "unprognostic (1.02e-1)" "unprognostic (2.04e-2)" "unprognostic (5.92e-2)" "unprognostic (5.26e-2)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (5.24e-2)" "prognostic favourable (2.76e-4)" "unprognostic (8.78e-2)" "unprognostic (5.31e-3)" "unprognostic (1.47e-3)" "unprognostic (5.81e-2)" "prognostic unfavourable (1.02e-7)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.69e-1)" "unprognostic (6.43e-3)" 26.6 57.2 53.6 22.9 52.7 18.8 37.2 73.1 84.6 26.1 28.3 22.6 28.4 27.7 29.9 55.4 29.0 66.8 26.4 68.6 53.3 33.4 52.5 44.6 34.4 35.5 70.8 36.1 34.9 27.8 38.7 66.8 35.4 53.0 27.4 23.5 28.0 47.4 30.6 41.8 24.8 22.3 33.0 53.2 27.7 31.0 24.8 63.5 21.9 36.1 37.9 32.8 26.1 25.6 28.0 52.3 7.7 38.3 32.8 29.4 36.4 14.1 12.9 45.2 19.5 18.2 15.0 10.2 9.8 10.6 11.1 16.3 72.1 12.0 0.1 18.3 8.0 9.1 29.3 11.2 10.9 41.7 24.6 49.9 40.4 37.5 11.7 40.8 7.6 18.1 12.5 7.3 4.0 24.6 29.2 40.0 17.9 12.9 18.7 78.8 33.1 32.4 32.1 69.1 14.5 75.9 20.6 18.5 24.8 18.8 21.7 13.8 12.3 68.9 10.7 3.0 13.5 10.7 21.7 34.5 50.8 0.2 1.7 0.1 14.8 7.7 38.3 3.2 29.4 36.2 25.5 28.0 20.6 24.6 44.8 23.2 24.3 29.2 1.8 32.8 33.3 52.3 21.9 36.4 53.6 52.7 73.1 84.6 53.3 33.4 70.8 36.1 53.0 63.5 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734950 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 183.4" "Cell line enriched" "Detected in some" 5 "ASC diff: 148.3" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 9.2" "Lineage enriched" "Detected in single" 20 "T-cells: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced 77000 "HPA047729: " "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavourable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" 4.6 1.6 1.1 3.0 3.1 0.3 2.4 9.9 3.9 0.6 1.0 1.6 2.7 0.5 0.8 8.7 1.5 0.9 1.9 3.0 1.8 0.9 2.6 183.4 7.2 1.3 8.2 2.0 12.6 0.9 0.3 1.5 26.5 3.3 7.1 0.9 1.5 0.6 3.0 1.5 6.3 0.9 2.7 1.3 3.5 1.4 2.3 2.5 0.0 1.0 0.6 0.6 3.9 1.4 0.2 0.0 0.2 0.1 0.4 9.2 0.8 0.0 0.0 0.0 0.0 148.3 15.4 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.6 0.2 9.2 2.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 2.4 0.8 1.1 3.1 9.9 3.9 1.8 0.9 8.2 2.0 3.3 2.5 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Predicted membrane proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.8;kidney: 119.9;salivary gland: 66.0" "Cell line enhanced" "Detected in some" "NTERA-2: 9.7;RPMI-8226: 11.5;RT4: 11.6;SCLC-21H: 12.8;SK-BR-3: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032443, HPA042186, HPA056385" Enhanced Approved Vesicles Vesicles "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favourable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 0.4 1.0 0.6 22.2 2.3 0.0 3.2 2.0 1.7 4.8 42.8 0.3 1.3 9.4 3.8 3.6 2.5 2.4 8.3 0.5 0.5 0.1 119.9 1.2 2.3 0.7 0.3 0.8 4.8 2.1 0.0 0.4 42.3 1.1 3.7 24.5 0.4 66.0 1.4 0.4 13.8 62.8 4.3 0.3 1.5 2.1 1.4 1.3 0.5 3.8 3.3 1.6 1.5 4.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.9 0.9 0.4 1.2 0.1 1.5 3.1 0.0 0.0 0.1 0.1 5.1 1.1 0.0 2.3 0.1 6.5 4.3 0.4 0.0 0.0 1.5 0.0 0.5 5.4 0.5 0.6 0.0 1.5 2.6 0.2 0.1 0.0 0.3 0.0 0.0 3.1 0.1 0.1 9.7 0.8 0.0 0.1 11.5 0.4 11.6 12.8 0.8 0.7 11.5 0.5 5.5 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 2.3 2.0 1.7 0.5 0.1 0.3 0.8 1.1 1.3 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122461525-122514908 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 198.9;ASC TERT1: 73.9;fHDF/TERT166: 67.4;HSkMC: 129.7;LHCN-M2: 98.6;U-87 MG: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.4;memory CD4 T-cell: 1.6" "Group enriched" "Detected in many" 20 "monocytes: 2.4;T-cells: 1.6" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" 24800000 2600000 "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (5.62e-6)" 40.8 21.8 64.5 9.1 79.0 0.5 48.2 16.2 62.8 50.4 19.3 60.8 7.2 5.6 47.6 67.0 15.6 19.5 78.7 28.7 50.8 35.4 34.7 60.4 14.6 9.1 62.7 32.5 111.3 14.5 37.6 26.9 114.1 41.9 19.5 14.0 20.7 19.3 31.5 7.5 29.6 9.3 40.5 46.5 10.5 12.9 9.8 49.5 1.7 13.3 8.5 7.1 41.5 27.3 0.0 0.0 0.0 2.4 0.0 1.6 0.7 0.0 3.4 1.5 0.4 198.9 73.9 0.0 8.5 15.6 3.5 1.9 0.0 0.0 0.0 2.3 67.4 1.0 0.6 9.7 0.5 0.0 0.3 0.0 5.7 0.0 10.1 0.0 0.0 129.7 35.7 2.0 16.6 16.3 0.0 0.1 98.6 1.7 0.0 0.0 1.6 5.4 0.0 0.1 0.0 22.5 0.1 0.1 0.3 21.4 0.0 9.2 0.6 0.0 10.7 25.1 0.3 11.3 7.2 0.0 0.0 0.0 81.4 0.0 11.7 0.0 2.4 0.0 0.6 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 64.5 79.0 16.2 54.6 50.8 35.4 62.7 32.5 41.9 49.5 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10270835-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.3;lung: 91.3" "Cell line enhanced" "Detected in many" "HHSteC: 31.1;Karpas-707: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002126, CAB002142, HPA004877" Enhanced Uncertain "Plasma membrane,Cytosol" 3100000000 "Plasma membrane, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favourable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavourable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 26.1 8.6 4.0 41.0 4.1 36.5 15.0 1.0 4.5 5.6 10.0 2.7 1.6 6.1 8.5 7.7 7.9 10.7 19.8 16.3 2.6 2.1 10.9 68.3 91.3 32.8 5.4 1.7 12.4 7.2 2.5 4.0 9.3 6.8 10.4 6.6 10.6 7.2 3.6 13.9 6.9 7.9 8.0 7.8 42.2 7.3 6.5 3.6 8.3 11.6 13.7 13.4 14.8 17.1 2.2 13.3 22.2 14.2 7.9 5.6 8.9 8.2 0.1 1.5 0.0 0.4 0.9 2.1 1.7 18.5 4.1 12.5 2.7 9.3 7.6 25.8 0.7 1.7 0.3 0.0 8.7 22.7 0.0 0.7 0.2 11.3 31.1 0.2 4.5 10.9 0.7 2.6 4.0 2.1 2.8 88.5 0.3 0.6 0.1 6.4 0.5 4.7 0.2 0.0 28.1 7.0 0.0 0.0 0.2 11.4 0.6 18.1 1.4 0.5 6.4 4.2 0.4 2.3 0.1 27.0 27.8 4.7 6.8 4.9 6.2 2.2 13.9 2.6 3.0 14.2 5.6 2.2 2.4 3.6 13.3 0.9 1.0 2.2 22.2 7.9 7.9 7.5 3.4 8.9 4.0 4.1 1.0 4.5 2.6 2.1 5.4 1.7 6.8 3.6 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159747 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.4;lung: 14.5" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2;U-266/70: 2.2;U-698: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "gdT-cell: 7.3;memory CD4 T-cell: 3.3;memory CD8 T-cell: 8.6;naive CD8 T-cell: 5.2" "Lineage enriched" "Detected in many" 7 "T-cells: 8.6" "Low region specificity" "Detected in single" CAB010344 Approved "Secreted to blood" 400 "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 2.4 0.9 0.3 4.5 0.3 14.4 0.5 0.1 1.0 1.4 0.9 0.5 0.0 0.2 0.6 1.4 1.3 0.2 0.6 1.0 0.3 0.3 0.7 4.1 14.5 8.5 1.5 0.4 0.4 0.2 0.0 0.5 0.8 0.6 1.2 0.4 1.1 1.4 0.2 1.7 0.3 0.7 0.7 1.3 4.1 0.8 0.2 0.0 0.8 1.3 3.1 4.7 2.2 0.6 0.5 0.0 0.2 0.0 1.2 8.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.3 8.6 0.0 0.5 0.8 5.2 0.2 1.2 0.0 0.0 0.2 1.1 0.3 0.3 0.1 1.0 0.3 0.3 1.5 0.4 0.6 0.0 IGFL4 ENSG00000204869 "IGF like family member 4" Q6B9Z1 19 46039748-46077118 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 8.5;skin 1: 13.9" "Cell line enhanced" "Detected in some" "A549: 7.7;HaCaT: 6.9;RH-30: 3.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA047655 Approved Approved Cytosol "Secreted - unknown location" Cytosol "HPA047655: " "unprognostic (1.22e-2)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" "unprognostic (7.96e-2)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (8.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (1.09e-2)" "unprognostic (3.59e-4)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" 0.1 0.8 4.4 0.3 4.4 0.2 0.3 3.9 8.5 0.2 0.3 0.0 0.0 0.9 1.0 2.9 1.9 0.4 1.1 1.9 2.8 2.8 0.3 0.4 0.7 0.9 1.2 6.0 2.0 0.2 3.3 4.5 0.2 2.1 0.9 0.5 4.6 1.1 0.0 0.5 13.9 0.7 0.1 1.6 0.5 0.7 0.8 0.5 0.0 1.5 0.6 0.2 1.2 0.2 0.3 1.6 1.3 0.7 0.2 0.5 0.1 0.1 7.7 0.2 0.6 0.0 1.3 0.5 0.0 0.0 0.0 0.0 1.7 0.3 1.1 0.1 0.1 6.9 0.0 0.0 0.0 0.8 1.2 0.0 0.9 1.9 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.9 0.1 0.6 0.3 0.4 0.1 3.3 1.6 0.0 0.4 0.5 0.5 0.0 0.2 2.0 0.5 1.4 0.7 0.9 1.6 0.5 0.5 1.0 0.5 0.2 0.2 1.0 2.1 1.3 0.7 0.7 0.5 0.3 0.3 0.3 0.2 0.1 0.1 0.3 0.1 0.4 0.9 0.2 0.1 1.6 0.4 0.1 4.4 4.4 3.9 8.5 2.8 2.8 1.2 6.0 2.1 0.5 IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206772494 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.3" "Group enriched" "Detected in some" 8 "HMC-1: 18.2;U-266/70: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 5.4;intermediate monocyte: 4.0" "Lineage enriched" "Detected in many" 5 "monocytes: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013120, HPA071391" Approved "Secreted to blood" 4757 "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" 10.9 3.1 1.1 10.7 1.2 4.1 2.1 0.3 1.3 1.6 1.8 2.1 0.5 0.8 1.0 1.9 1.7 4.0 5.2 3.9 0.8 0.9 1.3 3.1 4.3 9.2 1.8 0.9 1.5 1.2 0.4 2.3 3.6 2.3 1.7 1.8 2.1 1.6 0.8 0.9 0.7 2.1 4.6 2.2 28.3 2.0 1.6 1.4 2.2 2.4 0.9 3.5 4.1 1.0 0.2 0.5 0.5 5.4 0.1 1.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.0 9.3 0.3 0.3 0.0 0.1 0.0 0.5 5.4 0.1 0.2 4.0 0.0 0.1 0.2 1.0 0.5 0.2 0.1 0.1 0.3 0.1 1.4 0.1 0.9 1.0 1.1 1.2 0.3 1.3 0.8 0.9 1.8 0.9 2.3 1.4 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986348-118003037 "CD markers, Disease related genes, Predicted membrane proteins" Receptor "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.2" "Cell line enhanced" "Detected in some" "Daudi: 14.5;HDLM-2: 36.2;Karpas-707: 13.6;RPMI-8226: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favourable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavourable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 11.3 6.5 2.9 29.6 3.5 27.2 7.2 1.1 3.0 3.4 7.9 4.7 0.5 3.8 5.5 11.0 4.3 4.9 9.7 7.6 3.0 3.6 5.0 6.4 13.6 49.8 4.7 1.4 3.4 3.6 1.3 3.4 6.9 4.5 5.8 7.5 6.4 7.9 1.9 2.6 3.0 17.6 5.0 8.0 56.2 4.9 3.1 3.5 9.6 3.6 3.9 32.2 9.5 3.4 4.6 15.4 1.2 23.9 23.7 30.7 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.1 0.0 0.0 0.2 0.0 0.0 36.2 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 2.6 13.6 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.8 0.4 3.8 0.0 5.4 0.0 1.1 15.8 0.8 19.7 23.9 14.2 4.6 19.0 22.7 15.4 2.3 6.9 12.3 1.2 23.7 18.8 6.0 30.7 22.8 2.9 3.5 1.1 3.0 3.0 3.6 4.7 1.4 4.5 3.5 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.8;lymphoid tissue: 194.7;tongue: 123.7" "Cell line enhanced" "Detected in some" "A-431: 20.6;HaCaT: 40.8;RT4: 39.8;THP-1: 11.5" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "classical monocyte: 17.1;myeloid DC: 17.1;neutrophil: 65.2" "Group enriched" "Detected in many" 332 "dendritic cells: 17.1;granulocytes: 65.2;monocytes: 17.1" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" 421933 Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavourable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavourable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavourable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 17.3 0.2 0.2 7.2 0.3 32.9 1.1 0.2 0.5 27.2 3.8 0.6 1.4 1.1 1.5 0.7 217.8 0.2 4.1 0.5 0.2 0.0 0.5 23.5 2.9 1.9 0.3 0.2 0.4 0.4 0.1 0.3 3.1 0.6 1.6 0.3 0.4 30.9 1.3 0.5 14.4 3.7 0.7 0.2 3.6 5.7 1.4 0.2 1.0 0.7 123.7 194.7 3.3 42.2 0.0 17.1 65.2 17.1 0.0 0.0 4.9 20.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.2 0.1 0.1 0.0 40.8 0.0 1.1 0.0 0.0 0.0 0.1 0.0 6.9 0.0 0.1 7.7 0.0 5.3 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.0 0.0 0.3 0.0 0.0 11.5 0.1 0.5 0.0 0.3 0.0 0.3 0.0 0.0 3.9 4.6 0.1 0.0 17.1 0.3 0.0 7.6 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 65.2 0.0 3.4 0.1 0.0 4.9 0.2 0.3 0.2 0.5 0.2 0.0 0.3 0.2 0.6 0.2 ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975482 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.6;testis: 18.0" "Cell line enhanced" "Detected in some" "AF22: 9.8;MOLT-4: 5.1;U-2 OS: 12.6;U-251 MG: 6.6" "Cancer enhanced" "Detected in some" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 0.8 1.1 9.8 0.9 6.4 1.4 0.5 2.1 14.6 0.7 2.9 3.6 0.1 0.7 0.9 1.4 0.9 0.8 1.3 3.1 7.2 7.7 6.3 1.3 1.4 1.0 2.7 8.0 0.8 0.7 0.5 3.3 0.8 3.1 2.3 1.2 2.8 0.8 2.8 0.8 0.7 0.8 2.0 2.3 0.7 0.7 18.0 3.1 1.9 0.9 0.0 1.1 0.9 0.3 0.0 0.4 0.3 0.0 0.0 0.3 0.5 0.0 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 2.3 1.9 0.0 0.0 0.2 0.0 3.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 5.1 0.0 3.4 0.0 0.0 0.3 0.7 0.7 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 12.6 0.0 6.6 2.3 0.0 0.5 1.4 1.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.5 9.8 6.4 2.1 11.4 7.2 7.7 2.7 8.0 3.1 3.1 INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 148 "pancreas: 467.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 2.1;SH-SY5Y: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB019430 Enhanced "Secreted to digestive system" "CAB019430: AB_10691857" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.3 0.1 0.0 0.3 0.0 0.4 467.6 0.0 0.1 3.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.3 0.1 0.3 0.0 0.0 0.0 INSM1 "IA-1, IA1" ENSG00000173404 "INSM transcriptional repressor 1" Q01101 20 20368121-20370949 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 13.2;brain: 15.5;pituitary gland: 29.2" "Cell line enriched" "Detected in some" 20 "SCLC-21H: 91.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "unprognostic (1.86e-2)" "unprognostic (5.25e-4)" "unprognostic (7.59e-2)" "unprognostic (3.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-3)" "unprognostic (4.34e-2)" "unprognostic (2.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-1)" "unprognostic (1.22e-1)" 0.4 13.2 2.4 1.2 4.6 0.2 0.5 15.5 3.8 0.1 6.2 2.8 0.2 5.5 0.1 0.1 0.1 0.1 0.2 0.1 3.4 4.4 0.2 0.1 0.3 1.1 1.8 1.4 0.1 5.5 0.1 29.2 0.1 1.0 0.6 3.6 0.0 0.1 0.6 0.1 0.3 3.7 0.2 0.4 0.5 10.4 0.7 1.4 8.3 0.2 0.0 0.7 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.7 4.5 0.0 0.0 91.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.4 4.6 15.5 3.8 3.4 4.4 1.8 1.4 1.0 1.4 ISL2 FLJ10160 ENSG00000159556 "ISL LIM homeobox 2" Q96A47 15 76336724-76342476 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 11.3;pituitary gland: 12.6;salivary gland: 11.8" "Cell line enhanced" "Detected in many" "HEK 293: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "neutrophil: 11.3;non-classical monocyte: 3.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.3;monocytes: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA075192 Approved "Rods & Rings" "Rods & Rings" "HPA075192: " "unprognostic (7.30e-2)" "unprognostic (7.96e-2)" "unprognostic (9.01e-3)" "unprognostic (4.44e-3)" "unprognostic (1.44e-1)" "unprognostic (7.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-1)" "unprognostic (9.03e-2)" "unprognostic (3.93e-2)" "unprognostic (3.55e-15)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "unprognostic (4.07e-1)" "unprognostic (2.26e-1)" 0.9 0.2 0.0 0.8 1.1 0.3 0.3 0.0 0.9 2.8 3.8 2.0 0.0 2.9 0.2 0.2 1.2 0.2 1.9 0.7 0.3 0.0 0.2 0.2 0.4 0.9 0.7 0.0 0.2 0.2 0.2 12.6 0.3 1.0 4.1 0.5 1.9 11.8 0.3 0.2 1.1 2.0 0.4 1.8 1.0 3.2 2.7 1.9 0.0 0.2 4.0 1.2 0.2 6.4 1.2 0.2 11.3 3.9 0.0 0.6 0.5 1.4 1.7 0.0 1.6 0.1 0.1 1.4 4.3 2.0 1.1 1.5 3.4 0.7 3.3 2.1 0.0 1.8 6.2 0.1 0.2 3.0 15.5 1.5 3.6 3.9 1.4 3.3 4.1 0.0 0.9 0.0 0.0 0.0 4.7 2.4 0.3 0.1 4.1 8.0 0.0 2.9 2.7 2.0 4.0 0.0 0.6 4.8 5.2 2.8 0.0 0.0 0.3 7.5 0.0 1.4 3.1 0.6 4.1 3.7 3.9 1.9 1.0 2.4 0.0 0.0 1.0 0.0 0.2 1.0 0.0 1.0 0.0 0.6 0.2 1.2 0.2 0.1 11.3 0.0 3.9 0.0 0.0 0.5 0.0 1.1 0.0 0.9 0.3 0.0 0.7 0.0 1.0 1.9 ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493348-4847840 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease mutation, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 46.6" "Cell line enhanced" "Detected in many" "HDLM-2: 34.3;HeLa: 25.0;HMC-1: 16.5;U-87 MG: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 782.1" "Low region specificity" "Detected in all" "HPA014765, HPA016487" Approved Approved Vesicles 37000 Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.43e-4)" "unprognostic (2.40e-1)" 4.8 8.2 6.1 7.4 18.6 3.2 11.9 39.5 30.2 10.2 7.4 1.7 21.5 2.4 18.4 13.2 7.8 10.1 11.8 5.3 8.7 5.1 8.7 2.5 6.4 7.1 4.8 10.4 14.2 2.7 46.6 7.3 4.6 3.8 15.0 3.7 12.5 9.6 27.4 3.2 3.2 5.0 17.4 3.7 6.0 5.5 3.0 4.3 7.0 19.3 0.6 8.6 14.1 10.6 8.9 3.6 5.4 1.6 1.2 2.2 1.2 0.0 1.2 0.2 0.6 9.8 0.4 3.2 0.2 0.2 0.3 0.3 0.3 0.3 4.3 0.4 0.4 0.0 0.9 1.1 0.5 34.3 1.3 12.4 25.0 1.6 13.5 5.2 16.5 2.6 0.7 1.7 0.5 1.4 1.3 5.0 1.3 0.5 2.3 1.8 0.9 3.8 1.4 0.2 0.3 1.1 1.1 0.1 8.3 2.2 1.4 2.3 0.9 7.5 1.7 0.8 1.4 1.1 1.0 7.6 3.7 2.9 20.4 5.6 1.7 5.4 1.6 1.9 1.5 1.0 1.9 6.6 1.7 1.5 2.1 8.9 2.2 1.9 0.8 1.2 0.7 3.6 1.3 1.2 6.1 18.6 39.5 30.2 8.7 5.1 4.8 10.4 3.8 4.3 ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26336515-26833198 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.1" "Cell line enhanced" "Detected in many" "TIME: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" "Endoplasmic reticulum" Nucleoplasm "HPA059144: , HPA062260: " "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" 8.8 20.6 12.8 14.5 13.8 6.1 18.5 9.3 15.0 7.9 9.9 7.8 3.7 6.0 7.2 7.8 12.0 7.3 8.0 7.1 14.2 6.0 14.4 47.1 6.5 8.1 12.8 4.6 8.0 9.2 17.4 9.9 11.9 13.0 6.6 7.8 4.8 17.6 3.8 4.7 13.3 8.9 5.4 20.3 12.5 5.9 3.4 15.3 35.3 5.3 6.6 10.7 5.5 8.1 4.3 9.0 17.3 5.2 3.6 3.1 0.7 2.6 1.1 1.6 2.6 4.9 5.0 1.7 2.5 3.4 1.7 1.8 0.1 1.4 9.2 1.6 3.3 2.9 8.6 5.2 2.3 2.2 2.8 7.4 2.4 14.8 4.5 6.6 3.3 4.7 0.7 3.7 6.8 16.3 3.2 2.9 2.2 2.2 4.6 8.8 7.1 0.8 1.5 3.8 5.8 4.0 4.2 0.5 2.6 11.2 2.0 6.2 4.2 3.3 35.6 3.5 1.3 3.4 3.1 2.7 2.1 17.2 3.2 3.0 2.2 17.3 5.2 7.1 2.4 2.2 2.0 4.2 2.1 1.9 1.0 4.3 2.5 2.2 13.5 3.6 3.0 9.0 3.1 0.7 12.8 13.8 9.3 15.0 14.2 6.0 12.8 4.6 13.0 15.3 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "basophil: 1.8;gdT-cell: 2.8;MAIT T-cell: 2.1;memory B-cell: 1.5;memory CD4 T-cell: 1.7;memory CD8 T-cell: 2.0;naive B-cell: 2.0;naive CD4 T-cell: 1.4;naive CD8 T-cell: 1.7;T-reg: 2.4" "Group enriched" "Detected in many" 10 "B-cells: 2.0;granulocytes: 1.8;T-cells: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 7.8 6.0 2.0 17.8 2.4 2.6 9.0 1.7 2.3 6.5 39.6 1.0 35.1 14.8 7.7 15.6 10.0 6.7 28.9 7.2 1.8 1.4 8.6 1.2 21.0 9.7 4.4 1.2 7.3 11.0 1.3 3.9 3.9 4.0 7.2 9.5 5.4 12.7 26.0 2.7 27.9 44.0 6.6 3.5 20.0 21.4 20.1 1.9 10.6 28.4 9.7 18.1 5.2 16.5 2.0 0.2 1.8 0.0 0.1 2.8 0.7 21.7 10.2 1.9 0.1 1.9 6.1 12.7 7.5 19.2 9.4 8.6 14.0 17.0 18.6 8.1 5.4 21.5 8.7 20.2 4.9 10.8 7.3 0.0 29.1 15.4 4.4 3.3 2.4 4.4 18.4 23.7 51.6 15.9 7.2 6.0 10.1 10.4 5.5 1.9 1.9 15.1 8.5 0.0 10.9 33.6 15.3 17.8 0.6 12.9 18.9 18.6 6.5 1.7 21.7 12.8 6.4 16.4 16.4 4.2 4.1 8.8 10.3 5.0 7.3 1.8 0.0 0.0 2.8 0.0 2.1 1.5 1.7 2.0 0.2 2.0 1.4 1.7 0.0 0.1 0.0 0.0 2.4 0.7 2.0 2.4 1.7 2.3 1.8 1.4 4.4 1.2 4.0 1.9 JAGN1 "FLJ14602, GL009" ENSG00000171135 "Jagunal homolog 1" Q8N5M9 3 9890554-9894349 "Disease related genes, Predicted membrane proteins" "Immunity, Protein transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067610 Approved Vesicles Vesicles "HPA067610: " "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-3)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (2.37e-2)" "unprognostic (6.36e-3)" "unprognostic (9.93e-3)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" 19.7 31.6 9.8 12.7 11.5 6.8 18.4 10.5 15.4 15.8 27.1 14.1 15.7 16.8 16.9 25.7 13.2 16.8 16.6 13.7 9.7 11.6 21.4 39.6 12.1 18.2 10.8 10.7 18.1 42.3 17.0 12.5 19.6 12.6 17.3 19.1 14.3 21.3 14.2 23.2 17.7 29.4 13.3 11.0 12.8 19.3 12.8 9.7 24.1 27.3 13.7 15.0 16.6 21.7 24.8 26.0 39.0 27.9 21.4 25.1 28.4 9.5 16.8 11.8 6.8 36.0 37.9 39.3 13.3 19.8 15.0 15.3 12.0 12.6 15.3 6.0 13.2 8.3 18.6 17.8 14.7 11.2 20.2 18.6 17.3 20.8 30.8 13.4 11.6 36.2 26.8 19.5 22.4 14.2 20.0 10.3 17.0 28.2 10.9 23.1 15.5 21.9 9.3 9.8 18.6 21.3 13.7 7.5 14.3 8.7 9.1 16.5 15.1 16.7 12.0 8.0 8.7 8.7 10.5 19.0 26.6 17.7 10.5 16.0 13.3 39.0 27.9 13.5 22.9 21.2 24.3 24.1 22.7 22.0 25.6 24.8 25.1 23.1 11.2 21.4 15.8 26.0 23.9 28.4 9.8 11.5 10.5 15.4 9.7 11.6 10.8 10.7 12.6 9.7 KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746106 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 7.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" "Plasma membrane" "HPA005539: AB_1078164, HPA056090: " "unprognostic (6.59e-2)" "unprognostic (3.33e-2)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (3.05e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" 28.9 5.3 23.9 8.7 23.2 1.4 15.5 17.7 18.2 18.2 17.4 28.5 7.6 8.8 26.5 10.3 33.7 12.7 13.2 46.5 21.9 10.4 19.8 39.4 10.0 6.9 21.4 14.8 16.9 17.0 9.5 14.7 18.2 16.5 23.4 11.2 14.8 17.9 24.4 24.2 20.0 9.2 27.6 21.3 3.9 10.7 12.1 23.5 2.8 16.2 8.2 8.8 28.9 26.3 1.5 7.1 0.0 0.2 0.2 4.4 1.0 2.0 4.3 1.4 26.8 22.2 8.5 7.4 13.6 9.6 1.1 1.4 10.9 0.9 16.6 3.3 16.8 4.5 5.8 11.1 2.0 8.0 3.0 0.0 6.3 34.4 3.1 3.9 0.0 4.8 15.6 1.2 13.5 11.5 0.8 21.0 8.6 5.1 1.6 16.8 1.9 3.3 0.6 2.9 3.0 9.1 13.2 0.6 0.0 1.3 4.0 18.1 2.6 3.1 16.9 3.1 1.1 4.0 6.2 3.6 21.5 0.0 2.1 7.6 5.8 0.0 0.2 0.0 0.2 0.2 0.0 1.5 2.3 0.8 0.7 1.2 4.4 1.4 0.0 0.2 0.0 7.1 3.0 1.0 23.9 23.2 17.7 17.6 21.9 10.4 21.4 14.8 16.5 23.5 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040023-20154404 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526" Supported Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB004526: AB_2128417, HPA002470: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 10.6 6.6 30.1 9.4 27.5 24.9 6.8 22.0 20.1 10.2 9.4 27.6 7.9 10.9 7.8 5.4 17.3 7.7 8.0 21.9 24.7 18.0 10.8 24.0 10.1 12.7 26.8 15.9 18.2 11.6 38.1 8.7 8.5 24.2 9.5 8.1 10.7 20.9 9.2 33.4 8.9 13.0 8.7 21.4 11.7 9.0 1.8 31.1 8.7 10.0 7.4 12.0 8.7 11.0 2.1 2.7 5.5 1.5 1.1 4.8 0.8 1.5 3.9 2.2 3.6 9.0 8.4 5.1 5.0 7.4 5.3 7.8 1.1 2.6 13.4 2.1 9.4 1.1 5.4 1.6 4.5 12.2 5.1 11.8 6.2 0.4 4.2 1.8 15.3 3.6 2.9 4.6 3.0 5.0 7.5 19.0 7.5 1.8 3.8 3.5 0.9 3.9 5.1 4.1 2.8 7.2 8.0 1.1 2.4 2.8 4.5 17.0 4.7 8.0 4.8 9.0 3.6 3.3 5.7 7.3 15.1 3.2 8.2 7.8 18.9 1.3 1.1 2.8 3.6 1.5 3.4 1.0 3.1 2.5 0.9 2.1 1.1 2.1 5.5 1.1 1.1 2.7 4.8 0.8 30.1 27.5 22.0 20.1 24.7 18.0 26.8 15.9 24.2 31.1 KCNA10 Kv1.8 ENSG00000143105 "Potassium voltage-gated channel subfamily A member 10" Q16322 1 110517217-110519175 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 3.2" "Cell line enhanced" "Detected in some" "U-2 OS: 1.4;U-87 MG: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 0.2" "HPA015061, CAB022564" Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB022564: , HPA015061: AB_1855573" "unprognostic (2.96e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 28.0" "Cell line enhanced" "Detected in some" "Karpas-707: 10.6;SCLC-21H: 2.7;U-2 OS: 2.4;U-266/70: 3.5;U-266/84: 5.3;WM-115: 2.9" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.1" "Lineage enriched" "Detected in single" 8 "T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" 3.2 1.4 7.1 2.2 13.1 0.8 1.2 17.2 28.0 1.2 1.6 3.1 0.0 1.4 1.0 1.3 1.7 1.1 1.6 1.6 7.2 6.1 0.9 0.9 1.0 1.9 7.2 14.5 1.1 1.9 0.8 1.4 0.7 21.1 1.8 2.0 1.4 1.8 2.4 2.1 1.6 1.6 1.6 2.8 1.3 1.3 2.5 3.8 0.3 5.3 0.0 3.5 1.4 0.5 0.5 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 1.4 0.0 0.0 2.7 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 2.4 0.0 0.0 3.5 5.3 0.2 0.1 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.3 0.5 1.8 1.3 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 4.1 0.1 7.1 13.1 17.2 26.3 7.2 6.1 7.2 14.5 21.1 3.8 KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110672465-110675033 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 59.4" "Cell line enhanced" "Detected in some" "HDLM-2: 12.4;Karpas-707: 25.6;U-266/70: 18.5;U-266/84: 16.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.3;T-cells: 11.5" "Low region specificity" "Detected in all" HPA016625 Approved "HPA016625: " "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" 1.9 1.3 4.0 7.8 5.7 5.6 1.3 5.0 5.6 1.7 3.1 0.5 0.0 3.2 1.1 0.4 1.1 1.3 2.3 1.4 3.5 4.3 1.5 1.3 7.8 14.5 1.5 3.1 1.3 0.9 0.4 1.8 0.9 3.1 1.1 2.6 0.5 3.7 0.3 0.5 0.8 5.9 0.7 1.9 7.7 5.3 1.4 1.5 59.4 2.1 0.3 10.9 5.8 1.3 3.3 1.0 0.0 0.7 0.9 11.5 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 5.3 0.0 0.5 0.0 0.0 0.0 5.1 0.0 0.0 3.6 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 18.5 16.6 6.4 0.0 1.5 0.0 0.0 0.7 0.0 7.2 0.0 8.2 2.3 10.8 11.5 1.0 3.3 8.5 6.4 0.0 0.9 0.1 0.5 9.5 2.9 4.0 5.7 5.0 5.6 3.5 4.3 1.5 3.1 3.1 1.5 KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009741-30017023 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease mutation, Dystonia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 16.5;brain: 39.0" "Cell line enhanced" "Detected in some" "U-2 OS: 1.6;WM-115: 2.1" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 39.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001977, HPA016422" Approved "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" 2.2 16.5 9.8 0.6 39.0 0.6 0.6 0.2 12.2 0.6 0.6 0.8 1.8 0.7 1.1 0.9 0.6 0.8 0.6 5.9 6.1 2.7 1.2 0.6 2.4 0.6 1.6 6.2 0.6 0.6 0.6 2.8 1.2 10.5 0.6 0.6 0.0 0.6 1.7 0.6 0.8 0.6 0.8 0.6 0.6 1.0 0.7 5.9 0.0 0.6 0.0 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.1 0.0 0.0 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 39.0 0.2 12.2 6.1 2.7 1.6 6.2 10.5 5.9 KCNA7 "HAK6, Kv1.7" ENSG00000104848 "Potassium voltage-gated channel subfamily A member 7" Q96RP8 19 49067418-49072941 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 40.6" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;U-251 MG: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (2.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.72e-1)" "unprognostic (1.68e-1)" "unprognostic (4.31e-2)" "unprognostic (3.17e-2)" "unprognostic (6.97e-2)" "unprognostic (2.94e-2)" "unprognostic (1.26e-1)" "unprognostic (2.21e-8)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (5.80e-2)" "unprognostic (5.29e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 40.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.6 0.3 0.0 0.0 1.1 0.9 3.3 0.8 0.9 0.8 0.2 0.7 0.3 0.4 2.0 0.0 0.2 0.7 0.4 0.0 0.1 0.0 0.5 0.9 0.4 0.2 0.2 1.3 0.1 0.2 0.0 0.4 0.6 0.2 1.4 0.4 0.1 0.6 3.9 0.1 0.3 0.1 0.1 0.0 0.5 1.1 0.1 0.5 0.3 0.6 0.5 0.3 0.4 0.1 0.4 0.2 0.5 0.4 0.4 1.5 0.2 0.1 0.5 1.1 0.7 1.4 0.5 0.9 3.9 0.7 0.3 0.3 0.6 0.4 0.5 3.3 0.8 0.7 0.8 0.4 0.5 0.5 0.7 0.7 0.2 1.1 0.7 0.8 2.6 0.9 0.7 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.1;thyroid gland: 25.7" "Cell line enhanced" "Detected in many" "HEL: 5.8;hTEC/SVTERT24-B: 9.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 300.5" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 12.6 5.9 7.5 1.1 41.1 1.4 3.5 10.7 16.4 5.7 2.9 4.6 2.5 1.6 3.4 11.9 2.1 2.7 2.7 4.8 12.3 4.3 1.8 2.3 3.1 0.9 3.7 10.3 2.8 3.7 1.8 1.2 1.3 3.0 21.1 1.8 7.2 3.4 17.9 1.7 1.3 1.9 2.6 2.6 4.3 1.3 2.7 12.3 0.0 25.7 1.0 0.5 2.0 3.0 1.0 4.3 2.4 1.2 0.9 2.7 0.4 0.8 0.8 1.2 0.3 0.1 0.0 2.5 2.2 0.0 0.0 0.2 1.7 0.2 0.6 1.1 0.0 0.5 0.0 0.0 0.0 0.6 1.7 5.8 1.0 2.6 0.0 1.6 0.5 0.0 0.0 9.1 0.0 3.6 0.2 0.5 0.4 0.2 0.5 1.0 1.8 0.4 0.9 1.2 4.6 0.0 0.4 1.3 1.4 0.5 1.1 1.1 1.4 0.9 3.7 1.5 0.9 2.4 1.9 3.2 0.7 0.7 4.5 1.9 1.6 2.4 0.6 0.2 1.5 0.7 2.7 0.9 1.4 1.3 0.9 1.0 1.2 1.3 0.1 0.9 1.2 4.3 1.7 0.4 7.5 41.1 10.7 16.4 12.3 4.3 3.7 10.3 3.0 12.3 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5991466-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.5;brain: 54.3" "Cell line enhanced" "Detected in many" "HL-60: 67.1;U-937: 71.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavourable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 6.9 4.8 37.8 21.5 34.7 57.5 2.7 13.5 54.3 2.7 4.2 4.2 0.5 3.7 3.4 2.1 4.1 6.2 8.1 8.1 44.6 13.1 10.9 3.8 13.9 31.2 16.1 24.7 3.2 2.2 1.3 6.1 4.5 28.7 2.7 4.1 10.8 3.1 2.5 4.0 9.0 7.4 5.0 5.8 21.9 5.3 3.1 4.7 13.9 2.4 0.5 17.0 9.0 1.7 6.8 19.6 11.4 21.1 9.2 19.8 22.8 2.5 7.0 0.6 0.8 0.3 1.2 2.3 1.3 8.5 1.4 1.7 2.5 1.1 14.9 4.3 0.9 0.9 0.5 0.1 0.8 17.3 2.3 18.2 7.0 4.2 1.3 67.1 0.5 1.3 0.3 0.9 1.7 1.1 0.5 28.2 0.7 2.2 12.9 28.9 0.4 3.1 2.6 2.1 17.6 0.2 0.0 4.3 1.5 1.0 1.2 22.1 1.0 25.9 0.2 0.3 2.5 2.5 1.4 21.4 25.0 21.1 2.6 71.5 0.5 2.1 21.1 11.4 19.8 17.6 18.7 6.0 13.0 19.1 19.6 6.8 13.8 14.5 9.0 9.2 15.4 8.1 13.6 22.8 37.8 34.7 13.5 54.3 44.6 13.1 16.1 24.7 28.7 4.7 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537391-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;lymphoid tissue: 8.6;pituitary gland: 9.2" "Group enriched" "Detected in some" 5 "HaCaT: 3.2;HDLM-2: 3.0;HEK 293: 7.4;SCLC-21H: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: " "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.8 1.9 3.8 0.6 5.3 0.4 0.7 0.3 9.7 0.5 0.7 0.0 0.0 1.2 0.4 0.4 1.1 2.1 0.5 0.4 7.1 3.1 0.5 0.4 0.6 0.5 0.9 7.8 0.4 2.4 0.4 9.2 0.5 3.2 0.7 0.7 4.2 0.5 0.5 0.4 0.4 1.6 0.5 1.6 8.6 2.4 1.7 0.4 0.9 0.4 0.0 0.9 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 3.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.3 0.3 9.7 7.1 3.1 0.9 7.8 3.2 0.4 KCNC2 Kv3.2 ENSG00000166006 "Potassium voltage-gated channel subfamily C member 2" Q96PR1 12 75040077-75209868 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 39.3" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" "Group enriched" "Detected in some" 8 "breast cancer: 1.5;prostate cancer: 4.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019664, CAB022571" Uncertain Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB022571: , HPA019664: AB_1855578" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (5.58e-3)" "unprognostic (4.46e-2)" "unprognostic (3.39e-2)" 0.7 0.7 8.7 0.7 12.9 0.7 3.3 0.4 39.3 0.7 0.8 1.9 0.0 0.7 0.9 0.9 0.7 0.7 0.7 0.7 7.4 10.4 0.7 0.9 0.7 0.7 4.7 13.5 0.7 0.7 0.7 6.0 0.7 19.1 4.4 0.8 1.3 1.1 0.7 0.7 0.7 0.8 0.7 1.0 0.7 0.7 1.0 0.6 0.0 0.7 0.0 0.7 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 12.9 0.4 27.3 7.4 10.4 4.7 13.5 19.1 0.6 KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971569 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8" "Cell line enhanced" "Detected in many" "HSkMC: 13.6;NB-4: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 1.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Approved Uncertain Nucleoplasm Nucleoplasm "HPA000524: , HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favourable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" 4.9 2.4 4.2 3.4 4.7 6.0 2.2 16.8 7.8 5.1 2.2 6.3 1.9 2.0 5.0 3.8 1.4 7.4 6.3 2.9 6.9 2.5 2.5 1.8 3.0 3.1 3.1 3.5 4.6 1.4 1.8 3.0 2.5 10.4 3.3 2.1 2.6 1.2 6.0 0.7 1.6 2.6 6.6 6.5 4.2 2.5 3.0 2.7 1.1 2.3 0.5 3.6 3.0 3.0 0.6 1.3 1.4 0.1 0.0 0.8 0.1 0.4 2.0 0.8 4.8 6.6 5.2 1.6 1.0 4.2 2.9 1.9 1.3 0.6 1.6 3.5 3.2 0.6 0.8 0.4 2.8 2.7 3.2 1.5 2.0 0.1 2.4 0.4 3.0 13.6 1.8 5.3 0.6 1.0 1.1 3.7 2.1 3.6 0.4 10.8 2.6 0.7 1.3 0.9 1.6 3.2 1.5 0.5 2.2 0.9 0.0 2.2 2.1 1.6 2.5 0.6 2.7 0.6 0.2 3.0 3.9 3.9 1.8 3.9 2.1 0.0 0.1 0.0 0.5 0.0 0.3 0.6 0.2 0.8 0.0 0.1 0.2 0.0 1.4 0.0 0.0 1.3 0.0 0.1 4.2 4.7 16.8 7.8 6.9 2.5 3.1 3.5 10.4 2.7 KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273668-120750331 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 41.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;HSkMC: 4.0;NTERA-2: 3.1;RT4: 3.2;SCLC-21H: 16.2" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Region enhanced" "Detected in all" "cerebellum: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced "HPA029068: AB_10601436" "unprognostic (4.22e-1)" "unprognostic (2.79e-4)" "unprognostic (3.79e-2)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-3)" "unprognostic (9.07e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.77e-3)" "unprognostic (1.51e-1)" "unprognostic (4.51e-4)" "unprognostic (4.07e-5)" "unprognostic (2.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.83e-3)" 2.9 1.0 3.9 1.0 6.7 0.3 1.9 41.1 20.6 2.4 0.7 1.5 0.0 0.7 5.6 0.5 0.5 1.7 7.0 0.5 3.7 5.4 0.3 0.4 0.6 0.5 4.2 3.6 5.9 0.6 2.5 6.6 0.8 12.1 0.5 0.6 0.0 0.7 1.7 0.5 0.3 0.5 3.7 3.7 0.3 0.5 2.9 4.5 0.0 0.8 1.1 0.3 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.6 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 3.1 0.2 0.0 0.0 0.0 0.0 3.2 16.2 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 6.7 41.1 5.3 3.7 5.4 4.2 3.6 12.1 4.5 KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989155 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease mutation, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" 3.3 0.8 6.8 3.1 6.9 0.0 2.1 25.9 11.9 1.3 2.5 1.3 1.3 0.3 4.1 9.6 3.2 3.4 4.2 5.5 5.6 5.6 1.3 11.6 1.3 1.3 8.9 5.7 1.3 2.2 4.1 1.5 1.3 1.6 9.2 1.6 1.9 1.3 10.0 2.8 5.1 1.3 7.7 1.3 2.0 1.7 1.3 1.3 1.3 1.3 2.3 1.3 3.7 1.3 0.5 0.4 1.2 0.3 0.9 0.3 0.7 0.0 0.0 0.3 0.0 0.5 0.1 0.1 0.4 0.0 0.0 0.0 0.8 0.1 0.0 1.6 0.6 0.5 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.3 16.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.5 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.3 0.4 0.5 0.3 0.2 1.2 0.9 0.3 0.3 0.1 0.7 6.8 6.9 25.9 9.3 5.6 5.6 8.9 5.7 1.6 1.3 KCNE2 "LQT6, MiRP1" ENSG00000159197 "Potassium voltage-gated channel subfamily E regulatory subunit 2" Q9Y6J6 21 34364024-34371389 "Disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 66.8" "Cell line enhanced" "Detected in many" "Karpas-707: 4.2;SCLC-21H: 5.0;U-266/70: 4.1" "Cancer enriched" "Detected in some" 6 "stomach cancer: 2.9" "Region enhanced" "Detected in single" "pons and medulla: 3.4" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 30.5" "Not detected" "Not detected" "HPA029706, HPA051553" Enhanced "HPA029706: AB_2673159, HPA051553: AB_2681532" "unprognostic (5.29e-4)" "unprognostic (3.13e-1)" "unprognostic (6.69e-2)" "unprognostic (2.65e-5)" "unprognostic (7.45e-2)" "unprognostic (7.33e-3)" "unprognostic (5.77e-3)" "unprognostic (6.02e-3)" "unprognostic (1.13e-1)" "unprognostic (3.33e-2)" "unprognostic (9.30e-2)" "unprognostic (3.41e-2)" "unprognostic (2.19e-3)" "unprognostic (1.48e-1)" "unprognostic (3.97e-2)" "unprognostic (2.02e-1)" "unprognostic (8.81e-2)" 0.1 0.0 0.2 1.2 0.2 0.0 0.1 0.1 0.9 0.1 0.2 1.3 0.1 2.4 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.1 0.1 11.8 0.0 0.1 0.1 3.4 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 1.2 0.1 0.1 66.8 0.8 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.4 1.6 2.2 1.6 0.0 2.0 0.7 0.8 0.3 2.0 3.7 0.2 0.2 2.7 0.9 0.5 0.0 0.1 0.8 1.0 0.8 1.3 0.0 0.0 0.2 0.0 1.0 1.0 1.2 0.9 0.2 0.0 0.0 0.7 0.5 0.2 0.1 0.0 0.0 0.0 0.2 4.2 0.3 1.6 0.2 0.7 2.8 1.6 0.7 0.6 1.0 0.4 0.2 5.0 0.4 1.4 0.6 1.3 1.3 1.0 0.0 1.2 0.6 0.5 0.3 4.1 2.3 0.7 0.4 2.1 1.1 0.0 1.6 2.2 0.6 0.1 0.6 0.8 1.1 0.5 1.6 1.4 2.0 0.3 0.0 0.0 0.0 0.8 1.4 0.7 0.2 0.2 0.1 0.9 0.1 0.3 0.2 0.1 3.4 0.1 KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 63.7" "Cell line enhanced" "Detected in some" "CACO-2: 11.1;EFO-21: 10.5;HEL: 33.3;NB-4: 21.0;THP-1: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 47 "basophil: 16.8;classical monocyte: 16.2;eosinophil: 9.3;intermediate monocyte: 17.4;myeloid DC: 7.6;neutrophil: 22.4;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 122 "dendritic cells: 7.6;granulocytes: 22.4;monocytes: 17.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA014849 Approved "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavourable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" 10.8 2.2 2.7 8.5 4.6 3.1 5.8 1.2 3.0 6.4 18.2 3.2 4.9 31.4 6.7 4.7 3.5 6.0 63.7 3.8 2.7 1.9 9.3 2.5 15.9 11.3 5.0 1.3 10.5 10.1 1.9 3.3 5.4 3.4 7.6 22.2 7.4 11.7 5.5 1.1 0.7 22.2 4.9 7.7 15.1 26.3 1.7 3.2 1.3 15.1 1.4 3.3 5.2 5.7 0.1 7.6 22.4 17.4 0.0 0.1 4.8 0.0 0.0 0.0 0.1 4.2 1.0 3.5 0.0 0.0 0.5 0.4 11.1 1.0 0.1 10.5 0.0 0.1 0.9 0.0 0.3 0.0 0.1 33.3 0.2 2.2 1.5 0.3 6.0 3.7 0.0 0.3 0.0 0.1 0.9 0.1 0.4 0.0 0.0 21.0 0.4 0.0 3.7 0.1 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 6.3 0.0 16.8 16.2 9.3 0.0 17.4 0.1 0.0 0.0 0.0 7.6 0.1 0.0 0.0 22.4 0.0 14.0 0.3 0.0 4.8 2.7 4.6 1.2 3.0 2.7 1.9 5.0 1.3 3.4 3.2 KCNE4 MiRP3 ENSG00000152049 "Potassium voltage-gated channel subfamily E regulatory subunit 4" Q8WWG9 2 223051814-223198399 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 27.0" "Cell line enriched" "Detected in some" 4 "AN3-CA: 59.6" "Cancer enhanced" "Detected in all" "breast cancer: 20.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 2.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011420 Approved Approved "Nuclear bodies,Microtubules" Microtubules "Nuclear bodies" "HPA011420: AB_1079170" "unprognostic (1.23e-1)" "unprognostic (2.02e-3)" "prognostic unfavourable (9.42e-5)" "unprognostic (2.17e-2)" "unprognostic (7.56e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (7.89e-2)" "prognostic unfavourable (2.02e-7)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" "unprognostic (6.24e-3)" "unprognostic (9.08e-3)" 9.0 2.4 5.5 7.5 5.7 0.2 6.6 2.6 11.9 4.5 3.3 1.2 1.4 0.8 21.9 4.4 3.7 3.4 14.8 3.5 6.5 2.5 2.4 3.6 2.1 3.3 9.4 0.7 9.2 6.4 0.7 5.3 4.6 8.7 3.7 1.4 11.6 2.3 4.2 2.1 2.1 2.3 27.0 21.5 4.7 4.9 2.2 8.4 0.0 5.2 1.7 0.6 7.7 12.5 0.7 0.3 2.3 0.3 0.4 0.3 0.0 0.0 0.3 0.0 59.6 13.7 1.4 0.0 1.4 1.3 0.3 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 2.3 0.0 2.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.3 0.0 4.4 0.2 0.0 0.0 0.0 1.4 0.0 1.1 2.3 0.3 0.2 0.3 0.1 0.3 0.2 0.3 0.2 0.0 0.7 0.3 0.3 0.9 0.4 0.2 0.3 0.1 0.0 5.5 5.7 2.6 11.9 6.5 2.5 9.4 0.7 8.7 8.4 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911937-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 36.9" "Cell line enhanced" "Detected in some" "A549: 16.5;MCF7: 5.8;T-47d: 7.2" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "amygdala: 70.7;basal ganglia: 55.9;cerebral cortex: 78.2;hippocampal formation: 69.5;olfactory region: 141.1" "Low region specificity" "Detected in all" "HPA014738, HPA062278" Enhanced Approved "Golgi apparatus" "Golgi apparatus" "HPA014738: AB_1852114, HPA062278: " "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.9 0.9 11.5 1.0 25.5 0.8 1.2 0.8 36.9 0.9 1.2 2.4 0.0 1.2 1.9 0.8 1.6 1.1 1.0 1.1 13.1 4.7 1.1 0.9 1.0 1.0 3.1 10.5 0.9 2.2 0.8 0.2 0.9 3.6 1.0 1.2 0.0 0.8 1.4 0.8 0.8 1.1 1.0 1.0 1.5 1.1 1.0 3.1 0.5 0.8 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 16.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.0 0.0 2.5 1.7 0.0 0.1 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 7.2 0.8 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.5 25.5 0.8 28.5 13.1 4.7 3.1 10.5 3.6 3.1 KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023129 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 25.8;endometrium 1: 48.3" "Cell line enhanced" "Detected in many" "hTCEpi: 26.3;U-138 MG: 20.0;WM-115: 16.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 27 "naive B-cell: 10.8" "Lineage enriched" "Detected in single" 87 "B-cells: 10.8" "Group enriched" "Detected in many" 5 "amygdala: 21.4;basal ganglia: 17.0;cerebral cortex: 15.2;hippocampal formation: 19.7" "Group enriched" "Detected in all" 4 "amygdala: 16.3;basal ganglia: 12.0;cerebral cortex: 22.5;hippocampal formation: 21.1" "HPA039530, HPA040024" Approved Approved Vesicles Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" 0.5 4.5 13.3 2.9 7.0 0.3 0.7 2.3 11.9 9.6 2.4 1.6 25.8 0.6 48.3 2.8 3.7 11.9 1.9 1.0 7.9 2.9 0.5 0.4 0.5 3.0 2.0 9.5 0.9 3.7 1.3 0.8 9.3 6.7 5.6 1.3 0.7 1.4 18.3 0.3 0.5 7.2 5.8 1.0 3.5 0.8 5.4 2.6 0.0 0.5 0.0 1.4 2.8 3.4 10.8 0.0 0.0 0.1 0.0 0.0 0.1 0.4 1.7 1.3 6.4 0.7 1.7 0.1 5.6 0.0 3.3 2.6 0.1 0.1 0.0 3.5 1.6 1.6 0.8 1.6 3.4 0.2 2.1 0.0 6.2 0.0 11.7 0.0 0.2 3.4 26.3 12.6 12.9 0.8 0.1 0.0 0.3 6.3 0.0 0.1 6.7 11.6 0.0 0.0 0.0 0.0 1.9 1.9 7.3 12.2 14.3 9.2 1.0 0.9 0.3 20.0 11.8 0.1 1.6 0.0 0.0 0.0 5.9 0.4 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 13.3 7.0 2.3 11.9 7.9 2.9 2.0 9.5 6.7 2.6 KCNG3 Kv6.3 ENSG00000171126 "Potassium voltage-gated channel modifier subfamily G member 3" Q8TAE7 2 42442017-42494097 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4" "Group enriched" "Detected in some" 4 "HAP1: 5.0;HMC-1: 17.3;NTERA-2: 11.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "amygdala: 9.0;basal ganglia: 11.4;cerebral cortex: 7.1;hippocampal formation: 4.4;olfactory region: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "amygdala: 3.9;basal ganglia: 4.7;cerebral cortex: 5.3;hippocampal formation: 6.6;midbrain: 3.0" HPA041625 Approved "Cytoplasmic bodies" "Cytoplasmic bodies" "HPA041625: " "unprognostic (1.56e-1)" "unprognostic (4.22e-3)" "unprognostic (2.48e-1)" "unprognostic (7.67e-3)" "unprognostic (7.95e-2)" "unprognostic (9.14e-3)" "unprognostic (4.83e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (2.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (2.76e-1)" "unprognostic (6.47e-2)" "unprognostic (1.23e-1)" 0.4 5.2 9.0 2.5 11.4 0.3 0.5 0.2 7.1 0.8 2.3 0.1 1.6 0.4 1.6 0.7 0.4 0.5 0.7 0.3 4.4 0.9 1.2 0.3 1.2 0.4 1.2 3.6 0.9 2.9 0.3 1.8 0.3 0.5 1.2 1.3 0.6 0.3 1.7 0.3 0.6 0.5 0.6 0.3 0.4 0.3 3.3 1.1 4.9 0.3 0.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 5.0 0.0 0.0 0.0 2.7 0.0 0.5 0.9 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 0.0 11.0 0.8 0.0 0.0 0.0 0.0 0.0 1.6 0.7 1.0 1.6 0.5 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 11.4 0.2 7.1 4.4 0.9 1.2 3.6 0.5 1.1 KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218667-84239750 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 8.8" "Cell line enhanced" "Detected in some" "AN3-CA: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 101.5" "Low region specificity" "Detected in many" "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" 0.7 2.8 2.6 0.2 1.8 1.8 0.1 0.7 3.5 0.0 0.1 1.6 0.0 0.1 0.3 0.8 0.4 0.2 0.3 0.1 2.8 2.0 0.2 0.1 0.1 0.5 2.8 0.0 0.6 0.3 0.0 1.1 0.2 2.3 0.4 0.2 8.8 0.4 0.1 1.0 2.1 0.4 0.1 1.3 0.4 0.4 0.7 1.0 0.0 0.4 0.0 0.1 0.4 0.0 0.9 0.8 2.4 0.6 1.3 0.6 0.2 0.3 0.3 0.9 3.2 0.3 0.3 0.8 0.6 0.0 0.0 0.0 0.6 0.7 0.5 0.4 0.2 0.4 0.0 0.0 0.2 0.2 0.7 0.5 1.1 1.0 0.2 0.1 0.3 0.1 0.0 0.1 0.3 0.1 0.6 1.4 0.0 0.8 0.3 1.0 0.8 0.8 0.3 0.8 0.1 0.0 0.8 0.8 0.6 0.7 0.4 1.8 0.6 0.3 0.5 0.5 0.4 0.9 0.4 0.6 0.3 0.4 0.7 0.5 0.6 2.4 0.6 0.6 0.4 0.3 0.3 0.4 0.4 0.3 0.2 0.9 0.4 0.6 2.1 1.3 0.3 0.8 0.4 0.2 2.6 1.8 0.7 3.5 2.8 2.0 2.8 0.0 2.3 1.0 KCNH1 "eag, eag1, h-eag, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134180 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 20.2" "Cell line enhanced" "Detected in some" "LHCN-M2: 4.2;RH-30: 7.1;RPTEC TERT1: 4.1;SH-SY5Y: 9.0;SK-MEL-30: 8.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014551, HPA019445" Enhanced Supported Vesicles Vesicles "HPA014551: , HPA019445: AB_1852118" "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.9 2.3 6.3 1.3 13.3 0.7 0.6 19.1 20.2 1.0 1.3 3.3 0.2 1.2 1.5 1.0 0.9 1.2 1.0 0.7 3.8 1.7 1.0 0.7 0.7 0.7 1.1 7.5 0.8 0.9 0.9 0.8 1.1 1.7 1.3 1.3 0.0 0.8 0.9 0.7 0.9 1.0 1.0 2.1 0.6 1.5 2.4 1.5 0.0 0.8 0.0 0.7 0.9 0.7 0.1 0.7 0.7 0.1 0.1 0.3 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.1 0.6 0.1 1.4 1.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.1 0.0 0.0 7.1 0.0 4.1 0.0 0.3 9.0 1.6 0.1 8.5 6.3 0.0 0.0 1.1 0.1 1.3 0.8 0.0 0.0 0.0 0.2 0.0 0.5 0.7 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.0 0.7 0.1 0.0 6.3 13.3 19.1 20.2 3.8 1.7 1.1 7.5 1.7 1.5 KCNH4 "elk1, Kv12.3" ENSG00000089558 "Potassium voltage-gated channel subfamily H member 4" Q9UQ05 17 42156891-42181278 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.2" "Cell line enhanced" "Detected in some" "HDLM-2: 6.2;K-562: 5.8;RPMI-8226: 11.1;RT4: 4.2;U-266/70: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 11.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (3.07e-3)" "unprognostic (1.02e-2)" "unprognostic (4.02e-2)" "unprognostic (1.70e-1)" "unprognostic (9.30e-2)" "unprognostic (2.08e-3)" "unprognostic (4.59e-3)" "unprognostic (1.56e-1)" "unprognostic (2.41e-1)" "unprognostic (9.92e-2)" "unprognostic (4.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.36e-6)" "unprognostic (9.52e-2)" "unprognostic (2.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.72e-3)" 1.2 1.0 0.7 2.4 11.2 0.7 0.3 0.0 7.9 0.7 0.3 0.1 0.0 0.7 0.2 0.1 0.1 0.4 0.5 0.7 0.4 0.9 0.2 0.2 0.3 1.0 0.3 1.0 0.2 0.3 0.0 0.4 0.3 0.0 0.5 0.3 0.0 0.8 0.5 0.2 0.4 0.5 0.3 0.1 0.8 0.6 0.9 2.6 0.0 0.2 0.0 1.1 3.1 0.1 0.4 0.6 0.6 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 1.4 0.0 0.0 1.1 0.0 0.0 0.0 6.2 0.5 0.9 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 5.8 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 11.1 0.0 4.2 2.5 1.4 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.0 0.8 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.7 11.2 0.0 7.9 0.4 0.9 0.3 1.0 0.0 2.6 KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.7;kidney: 15.4;pituitary gland: 7.6;retina: 7.6" "Group enriched" "Detected in some" 6 "SCLC-21H: 8.5;SH-SY5Y: 3.3" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "olfactory region: 4.7" HPA061704 Approved "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" 0.0 0.2 0.3 0.7 1.1 0.3 0.0 0.1 1.2 0.0 4.2 0.0 0.0 3.9 0.0 0.5 0.0 0.3 0.1 0.6 0.3 2.8 15.4 0.0 0.9 0.1 1.1 0.5 0.1 2.4 0.1 7.6 0.6 1.0 6.2 0.4 7.6 0.1 0.0 0.2 0.3 8.7 0.0 0.7 0.1 1.7 1.4 0.3 0.3 0.1 0.0 0.0 0.1 0.0 0.8 0.4 1.7 0.5 0.7 0.5 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.2 0.7 0.2 0.1 0.1 0.0 0.0 0.3 8.5 3.3 0.0 0.2 0.1 0.3 0.2 0.0 0.3 1.0 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 1.2 0.5 0.4 0.4 0.3 0.1 0.6 0.2 0.2 0.2 0.8 0.5 0.4 1.7 0.7 0.3 0.4 0.2 0.4 0.3 1.1 0.1 1.2 0.3 2.8 1.1 0.5 1.0 0.3 KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838730 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.0;pituitary gland: 5.4" "Group enriched" "Detected in some" 13 "SCLC-21H: 10.5;SK-BR-3: 9.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;neutrophil: 3.0" "Lineage enriched" "Detected in single" 15 "granulocytes: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018039 Uncertain "HPA018039: AB_1852125" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.66e-1)" "unprognostic (5.55e-2)" "unprognostic (3.05e-2)" "unprognostic (5.51e-2)" "unprognostic (8.12e-3)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.55e-3)" "unprognostic (2.76e-3)" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.68e-2)" 0.4 1.0 4.4 0.9 6.8 0.8 0.4 6.0 11.0 0.4 0.4 0.0 0.7 0.7 0.4 0.6 0.4 0.5 0.4 1.0 2.6 1.8 0.6 2.7 0.5 0.5 0.7 4.6 0.4 1.0 0.3 5.4 0.6 3.1 0.4 0.3 0.4 0.4 1.5 0.3 0.4 0.5 0.4 0.7 1.1 2.5 1.6 0.3 0.0 0.4 0.0 0.3 0.4 0.4 0.1 0.1 3.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 10.5 0.7 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 3.0 0.0 0.1 0.0 0.0 0.0 4.4 6.8 6.0 11.0 2.6 1.8 0.7 4.6 3.1 0.3 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148454-19535646 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 31.3;pituitary gland: 16.1" "Cell line enriched" "Detected in some" 4 "SH-SY5Y: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 4.5" "Lineage enriched" "Detected in single" 5 "B-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.6 7.0 8.4 1.6 22.0 1.4 2.4 1.3 11.4 1.3 1.9 31.3 0.0 2.2 1.2 1.2 0.7 1.4 2.2 1.0 11.8 5.7 0.7 0.7 0.8 3.2 16.4 10.2 0.7 2.7 0.8 16.1 0.6 15.0 2.2 2.5 0.1 3.3 1.4 0.6 1.9 1.8 1.1 9.9 2.6 5.9 4.0 18.1 0.0 1.1 0.0 3.2 0.9 0.5 4.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 9.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 4.5 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 8.4 22.0 1.3 11.4 11.8 5.7 16.4 10.2 15.0 18.1 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061765-90185857 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.3;parathyroid gland: 14.3;testis: 13.2" "Cell line enhanced" "Detected in some" "MCF7: 2.3;RT4: 5.1;SCLC-21H: 2.2;SK-BR-3: 2.2;U-2 OS: 2.5;U-266/84: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "classical monocyte: 1.5;intermediate monocyte: 1.3;myeloid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;monocytes: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" "Nuclear speckles, Cell Junctions" "HPA003514: " "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.8 1.1 2.9 2.2 3.5 0.1 0.4 0.2 4.2 0.4 0.6 4.0 0.0 0.6 0.3 1.5 0.3 0.4 0.5 2.7 2.9 2.4 4.8 0.7 0.7 1.6 6.3 1.4 0.4 2.7 14.3 0.6 1.2 3.6 0.4 0.7 0.1 1.1 0.7 0.1 0.1 0.7 0.4 8.3 1.1 0.5 13.2 5.4 0.7 2.7 0.0 0.6 0.8 0.1 0.0 3.8 0.0 1.5 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.9 1.2 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.5 5.1 2.2 0.7 0.0 2.2 1.4 0.0 1.9 0.0 0.0 2.5 0.0 0.8 0.7 2.2 0.0 0.2 0.0 0.1 0.0 1.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.3 2.9 3.5 0.2 4.2 2.9 2.4 6.3 1.4 3.6 5.4 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.4" "Cell line enhanced" "Detected in many" "RH-30: 33.1;RPMI-8226: 13.3;RT4: 22.5;U-266/84: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 17 "B-cells: 1.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavourable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.2 1.1 2.7 5.6 3.2 0.4 14.8 0.5 5.1 6.8 7.9 4.8 1.3 3.1 4.5 2.4 7.2 3.3 5.3 4.6 3.9 3.4 4.2 2.6 17.6 1.2 6.8 1.4 1.1 7.7 1.9 0.8 8.3 15.2 4.4 4.1 9.9 7.6 2.8 54.4 3.7 4.3 9.7 4.7 1.1 7.0 3.9 1.4 0.2 2.4 19.0 3.6 5.0 4.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.6 0.3 0.0 0.8 0.4 1.8 1.3 4.0 0.8 1.0 0.0 8.1 0.0 0.4 1.4 1.2 9.8 0.0 0.9 0.0 2.5 0.0 0.1 0.0 4.0 0.1 0.3 0.3 6.2 0.0 0.6 0.2 0.2 0.0 0.5 1.0 0.0 0.0 4.8 0.1 1.1 33.1 13.3 0.8 22.5 9.8 0.3 0.0 2.5 2.7 1.3 0.0 0.0 1.3 0.0 0.1 9.9 0.0 15.4 0.0 7.4 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.2 0.5 5.1 3.9 3.4 6.8 1.4 15.2 1.4 KCNT1 "KCa4.1, KIAA1422, SLACK, Slo2.2" ENSG00000107147 "Potassium sodium-activated channel subfamily T member 1" Q5JUK3 9 135702185-135795508 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.7;skeletal muscle: 19.5" "Cell line enhanced" "Detected in some" "RH-30: 2.0;RPMI-8226: 4.5;SCLC-21H: 6.8;SH-SY5Y: 1.4" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059880 Uncertain "HPA059880: " "unprognostic (1.50e-3)" "unprognostic (1.72e-2)" "unprognostic (2.07e-3)" "unprognostic (2.98e-13)" "unprognostic (9.26e-2)" "unprognostic (7.73e-2)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.30e-3)" "unprognostic (9.89e-2)" "unprognostic (6.20e-2)" "unprognostic (4.89e-7)" "unprognostic (9.15e-2)" "unprognostic (2.70e-1)" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" 1.4 0.8 7.3 1.0 12.4 1.0 0.7 29.7 29.3 0.7 0.9 0.2 0.0 1.0 0.8 0.9 1.2 0.9 1.1 1.8 5.3 4.2 0.7 0.7 0.9 0.8 1.8 12.0 7.3 0.8 0.7 4.7 1.2 6.1 0.8 0.8 0.0 0.7 0.8 19.5 0.8 0.8 0.8 2.1 9.6 1.4 1.9 3.1 0.0 0.8 0.0 0.7 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 2.0 4.5 0.0 0.0 6.8 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 7.3 12.4 29.7 29.3 5.3 4.2 1.8 12.0 6.1 3.1 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963645-109975847 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 22.4" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.5 0.5 10.6 0.6 10.2 1.1 0.6 0.2 22.4 0.4 1.1 0.0 0.0 0.5 0.6 1.2 0.5 0.4 0.5 0.5 3.9 1.6 0.6 0.5 0.5 0.7 0.9 8.2 0.8 1.0 0.4 0.7 0.6 0.9 0.7 0.9 0.0 0.6 0.5 0.5 1.1 0.8 0.4 0.4 0.6 0.5 0.7 0.0 0.0 0.9 0.0 0.5 0.4 0.2 0.8 0.6 2.5 0.9 0.6 0.5 0.1 2.0 2.6 1.9 0.8 0.3 0.3 0.7 0.6 0.0 0.4 0.4 0.5 0.8 0.7 0.6 0.1 2.1 0.7 0.3 0.5 1.0 0.3 1.2 2.0 0.5 0.1 1.1 1.5 0.3 0.4 0.6 0.5 0.4 1.0 2.6 0.3 0.6 0.8 1.2 0.9 1.2 0.2 1.0 0.3 3.4 1.0 1.5 0.7 0.4 0.4 0.6 1.0 0.5 1.3 2.3 1.9 1.5 0.6 0.9 0.5 0.4 1.0 0.9 0.9 2.5 0.8 0.3 0.5 0.9 0.4 0.6 0.5 0.5 0.5 0.8 0.5 0.5 1.1 0.6 0.8 0.6 0.3 0.1 10.6 10.2 0.2 19.5 3.9 1.6 0.9 8.2 0.9 0.0 KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717502-2730037 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 82.3" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HDLM-2: 2.8;HeLa: 2.3" "Cancer enriched" "Detected in single" 78 "testis cancer: 6.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced "HPA031131: AB_10609996" "unprognostic (5.06e-2)" "unprognostic (1.47e-3)" "unprognostic (3.45e-3)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.12e-3)" "unprognostic (5.38e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.35e-1)" "unprognostic (7.96e-8)" "unprognostic (3.01e-1)" "unprognostic (4.90e-2)" "unprognostic (9.90e-2)" "unprognostic (1.06e-2)" 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 82.3 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.1 0.0 0.6 0.0 0.2 0.7 0.2 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.9 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 2.8 1.3 0.8 2.3 0.3 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.5 0.6 0.1 0.2 0.0 0.3 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.1 0.6 0.0 0.0 0.7 0.3 0.5 0.3 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100772 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 60.2;kidney: 38.4;liver: 67.0" "Cell line enhanced" "Detected in many" "HEL: 18.5;Hep G2: 26.9" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Cytosol 320000 Cytosol "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavourable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 0.9 1.9 2.1 1.2 2.7 0.7 1.9 5.2 3.9 1.1 22.3 1.9 0.2 40.0 1.5 0.9 1.1 1.6 0.6 0.6 2.2 2.2 38.4 67.0 0.7 0.8 3.5 1.9 1.8 4.2 0.6 0.7 0.4 3.0 0.9 0.6 0.6 1.7 0.7 1.4 1.0 60.2 0.9 1.8 0.8 1.0 1.6 3.6 0.0 0.5 1.2 0.6 0.7 0.9 5.1 7.3 0.6 6.6 5.4 8.8 6.0 13.9 10.6 1.6 6.4 1.2 0.3 1.4 0.9 0.6 1.3 0.8 5.1 3.0 2.1 3.4 0.0 6.2 5.5 1.8 0.4 4.9 10.0 18.5 2.8 26.9 0.6 2.5 2.2 0.1 0.8 1.6 0.1 1.2 3.3 3.5 0.1 9.1 3.0 2.0 2.3 4.2 10.6 0.8 11.8 1.6 1.7 6.0 9.3 2.0 3.6 3.9 1.6 1.1 1.1 0.4 2.1 0.9 3.7 4.4 7.8 3.6 1.8 6.0 1.0 0.0 6.6 0.4 5.4 3.8 7.4 5.1 8.8 7.8 6.1 5.1 6.4 7.8 0.6 5.4 1.6 7.3 5.5 6.0 2.1 2.7 5.2 3.9 2.2 2.2 3.5 1.9 3.0 3.6 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009010-32056431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" 260000 "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 26.3 19.9 55.7 20.2 55.5 34.1 23.0 22.2 42.4 23.8 34.2 21.7 20.9 23.5 25.7 17.8 28.0 20.3 28.0 48.4 51.5 39.3 21.1 15.3 23.8 16.5 62.9 26.1 18.2 18.9 56.8 22.4 27.7 38.3 31.8 30.0 8.9 20.1 25.6 34.3 17.6 28.6 37.2 80.4 21.1 23.1 27.7 43.7 25.0 23.5 21.5 16.1 33.8 28.1 13.8 27.6 30.0 18.9 13.4 16.5 9.2 29.4 25.1 34.0 23.8 24.4 26.9 14.5 40.7 19.3 31.5 26.9 27.5 32.6 20.2 17.7 48.3 24.5 31.0 26.0 42.3 17.4 16.9 25.7 23.5 26.8 28.1 17.8 28.3 21.8 37.0 36.3 25.4 40.2 30.9 21.3 43.5 17.7 18.6 10.1 5.5 11.5 24.4 63.4 8.3 24.3 20.7 33.1 24.2 31.5 12.6 30.3 15.2 25.6 33.5 32.1 30.1 37.1 30.1 6.4 7.4 23.9 30.6 36.9 30.1 20.8 15.2 24.2 11.8 18.9 11.4 13.6 14.9 12.5 14.2 13.8 13.3 13.0 30.0 13.4 18.9 27.6 16.5 9.2 55.7 55.5 22.2 42.4 51.5 39.3 62.9 26.1 38.3 43.7 KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "pancreas: 38.5" "Cell line enhanced" "Detected in some" "HDLM-2: 15.5;HMC-1: 25.0;U-937: 5.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "memory CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 5 "T-cells: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" "Centriolar satellite" "HPA071587: , HPA074326: " "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.72e-3)" "unprognostic (3.30e-2)" "unprognostic (5.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.62e-2)" "unprognostic (2.43e-6)" "unprognostic (1.72e-1)" "unprognostic (4.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.62e-2)" 0.2 0.0 0.4 0.3 0.8 0.0 0.0 0.2 1.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.5 0.2 0.4 0.0 38.5 0.0 0.9 0.1 0.5 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.2 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.1 2.2 0.0 0.0 15.5 0.0 0.0 0.0 0.2 0.0 0.0 25.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 3.1 1.0 0.0 0.0 0.0 0.0 3.9 0.0 0.6 1.0 0.2 0.0 0.0 0.0 0.3 0.0 5.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.2 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.8 0.2 1.2 0.7 0.0 0.2 0.4 0.5 0.2 KL ENSG00000133116 Klotho Q9UEF7 13 33016433-33066145 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 64.3;parathyroid gland: 76.9;placenta: 25.5" "Group enriched" "Detected in some" 5 "HMC-1: 5.0;SK-BR-3: 9.4" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Region enhanced" "Detected in some" "pons and medulla: 11.6" "Cell type enhanced" "Detected in single" "classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Secreted to blood" 510400 "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favourable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favourable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 4.8 0.6 0.8 0.9 4.3 0.1 7.4 0.0 0.8 0.7 2.1 3.3 0.2 1.0 1.0 3.2 0.8 0.7 0.9 0.9 2.4 0.8 64.3 0.2 10.4 0.9 0.5 0.3 0.4 1.6 76.9 0.3 25.5 11.6 3.3 0.4 0.3 0.7 1.0 0.9 0.4 3.2 0.7 0.4 3.1 1.9 0.6 0.3 0.0 1.4 1.3 0.3 1.5 1.1 0.0 0.0 0.0 1.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 4.3 0.0 0.8 2.4 0.8 0.5 0.3 11.6 0.3 KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030490 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favourable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" 22.2 10.1 10.3 15.1 12.0 40.7 17.3 30.2 12.0 12.2 12.1 14.6 9.3 5.7 19.7 13.4 11.6 10.2 13.8 12.1 10.3 8.0 9.9 8.4 17.1 15.7 12.9 9.1 17.1 6.1 3.0 6.4 7.0 17.4 10.2 6.7 7.0 8.9 9.3 6.2 7.9 11.9 24.2 25.7 11.3 10.7 7.9 14.7 14.4 10.8 8.5 8.3 18.4 18.2 4.5 3.0 24.0 11.7 12.9 9.0 3.5 4.4 3.2 8.7 0.6 3.0 7.9 1.8 5.2 4.2 8.2 3.6 0.0 3.7 0.0 3.4 10.7 11.2 7.3 24.2 4.4 3.1 0.4 0.1 8.8 1.8 5.3 2.3 3.6 10.5 8.2 5.7 18.9 9.5 0.0 4.3 6.3 0.1 2.8 0.8 5.1 1.6 1.2 2.3 3.2 1.9 3.5 13.4 16.4 4.5 6.4 4.2 1.0 3.6 18.8 16.4 7.9 6.9 6.2 3.3 2.2 0.0 14.4 2.0 3.2 11.5 5.4 6.8 0.9 6.8 0.4 3.0 5.1 1.0 3.0 4.5 9.0 6.1 24.0 12.9 11.7 1.4 4.1 3.5 10.3 12.0 30.2 12.0 10.3 8.0 12.9 9.1 17.4 14.7 LMX1A "LMX1, LMX1.1" ENSG00000162761 "LIM homeobox transcription factor 1 alpha" Q8TE12 1 165201867-165356715 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.3;pituitary gland: 8.0" "Cell line enriched" "Detected in single" 12 "SCLC-21H: 4.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028051, HPA030088" Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA028051: AB_10599731, HPA030088: AB_10601106" "unprognostic (1.73e-1)" "unprognostic (9.57e-2)" "unprognostic (7.58e-2)" "unprognostic (1.59e-1)" "unprognostic (2.17e-1)" "unprognostic (2.82e-1)" "unprognostic (2.63e-1)" "unprognostic (3.22e-2)" "unprognostic (2.10e-3)" "unprognostic (1.51e-1)" "unprognostic (9.82e-3)" 2.2 0.0 0.0 2.0 0.0 0.0 1.2 2.6 0.5 0.5 1.7 3.4 3.1 4.0 0.1 1.3 1.1 0.5 0.2 0.2 0.9 1.5 0.0 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.1 8.0 0.0 7.3 0.2 2.1 0.5 1.5 0.3 1.4 0.3 2.2 0.9 0.1 0.0 0.2 4.3 0.3 0.0 0.3 3.5 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.9 1.5 2.2 0.0 7.3 0.3 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 18.1 10.1 13.0 10.7 18.3 6.0 22.1 20.0 16.4 10.5 8.6 10.9 7.3 8.9 11.0 15.0 20.0 7.0 10.4 12.8 11.6 11.9 7.6 13.2 8.0 15.4 13.2 11.2 19.3 7.5 17.2 32.0 9.0 17.9 9.6 7.1 9.0 14.4 11.6 88.4 6.5 9.2 11.0 10.3 8.4 7.6 39.0 13.2 8.3 8.1 14.0 19.2 10.4 21.7 6.5 9.6 11.6 2.8 8.0 11.1 3.2 5.4 6.5 5.4 12.1 25.1 27.9 2.8 7.6 13.2 5.0 8.6 2.3 5.4 2.7 1.0 6.5 5.9 6.1 16.8 4.6 11.2 3.4 6.7 3.6 3.5 8.8 4.6 31.6 25.1 7.5 20.5 7.8 9.5 9.2 24.3 3.6 2.1 4.3 4.0 5.6 6.6 6.0 10.0 17.0 12.5 3.5 15.1 11.9 2.7 6.6 17.3 1.6 2.6 6.7 7.9 7.1 5.0 6.6 38.2 29.5 5.1 11.1 8.3 5.8 9.5 2.8 11.6 10.3 2.1 11.1 6.5 9.6 9.7 2.5 5.0 8.4 7.1 1.1 8.0 2.1 9.6 10.5 3.2 13.0 18.3 20.0 14.4 11.6 11.9 13.2 11.2 17.9 13.2 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013315 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "granulocytes: 20.8;NK-cells: 10.1;T-cells: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: " "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favourable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 6.8 5.6 13.0 10.5 18.4 9.2 7.7 11.9 16.5 6.6 25.2 10.4 2.4 31.6 6.7 3.9 5.9 6.3 14.3 5.1 11.0 14.5 20.7 83.9 11.8 11.8 11.2 9.8 8.8 9.0 9.7 8.2 16.3 15.3 5.8 7.4 6.8 4.4 5.3 2.2 2.7 43.3 6.1 9.6 10.7 15.6 13.5 9.6 6.3 7.5 1.5 10.0 6.8 6.7 1.2 1.1 20.8 2.0 10.1 9.5 2.1 4.9 6.7 10.6 3.7 18.4 17.1 6.3 11.9 14.6 11.9 11.6 8.7 4.2 3.6 7.3 18.3 0.2 8.7 3.7 9.4 7.0 1.8 9.2 5.2 9.9 17.2 7.3 10.1 17.2 2.5 11.8 10.3 14.8 8.3 1.9 16.6 3.7 9.1 6.3 3.4 9.6 16.0 9.2 13.4 9.5 11.1 8.9 6.2 11.2 5.3 3.8 0.0 10.0 20.8 15.4 18.7 19.7 8.8 3.5 5.3 7.8 13.6 7.5 5.4 6.5 2.0 6.1 9.3 1.3 9.5 0.9 7.1 5.3 0.8 1.2 7.3 4.7 20.8 10.1 0.6 1.1 6.3 2.1 13.0 18.4 11.9 16.5 11.0 14.5 11.2 9.8 15.3 9.6 LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312609-68449275 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease mutation, Osteogenesis imperfecta, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.8" "Lineage enhanced" "Detected in single" "dendritic cells: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Approved "CAB013001: AB_2533267, HPA030505: " "unprognostic (3.67e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.13e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.94e-2)" "unprognostic (9.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.78e-1)" "unprognostic (6.82e-2)" "prognostic favourable (3.55e-10)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.42e-2)" 15.9 14.7 3.1 6.8 4.0 1.1 25.6 1.6 3.7 13.5 14.9 5.3 16.8 20.4 12.4 11.8 8.7 10.1 29.8 14.3 2.9 2.1 12.5 49.4 12.9 4.8 2.9 2.6 11.8 30.8 8.1 6.9 12.7 5.2 13.3 5.3 11.6 35.3 22.0 7.4 8.9 23.5 15.4 3.1 3.6 12.7 3.6 3.4 9.2 17.2 10.4 8.3 11.2 17.5 0.1 2.8 0.0 0.0 0.7 0.1 0.0 9.9 34.0 3.7 8.4 7.0 3.9 15.8 4.6 4.0 2.8 2.5 19.1 34.5 0.0 29.6 5.9 12.8 3.3 12.3 0.4 1.6 7.5 7.0 17.4 24.7 7.2 5.0 0.6 5.6 4.2 0.1 4.6 7.9 12.2 0.5 2.0 22.4 7.5 20.1 6.5 13.9 9.5 10.1 16.0 4.7 26.9 3.6 7.3 12.2 16.5 13.3 11.5 11.7 10.3 0.0 3.1 3.8 5.1 2.1 0.2 2.0 0.0 3.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 2.8 0.0 0.0 3.1 4.0 1.6 3.7 2.9 2.1 2.9 2.6 5.2 3.4 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503638-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1" "Cell line enhanced" "Detected in some" "HEL: 5.3;NB-4: 10.3;RH-30: 5.0;THP-1: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 8.3;plasmacytoid DC: 7.0" "Group enriched" "Detected in many" 10 "dendritic cells: 7.0;T-cells: 8.3" "Low region specificity" "Detected in many" HPA059545 Uncertain Approved Vesicles Vesicles "HPA059545: " "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 1.0 0.5 0.5 5.1 1.6 3.1 0.5 2.0 3.2 0.6 8.2 0.5 1.9 10.6 1.3 1.1 1.2 0.3 2.0 2.2 0.5 0.1 3.5 4.3 15.1 0.6 0.5 0.5 1.0 0.5 1.0 0.7 8.9 0.5 0.7 4.8 4.3 11.7 0.5 2.0 0.9 10.7 0.5 0.5 5.5 8.3 2.4 0.8 0.5 0.7 0.5 2.2 0.6 0.7 0.7 7.0 0.0 0.0 0.0 8.3 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.6 0.9 1.3 2.4 0.0 0.0 0.1 0.7 0.0 2.9 0.0 0.4 0.2 1.4 5.3 0.0 0.0 2.3 0.0 0.0 0.4 0.4 0.0 0.1 0.0 2.0 0.0 2.0 0.0 0.0 10.3 0.4 0.2 0.2 5.0 0.1 0.0 0.0 0.5 3.3 0.1 0.2 0.0 0.2 15.8 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.6 0.0 8.3 0.7 0.5 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.2 0.5 1.6 2.0 3.2 0.5 0.1 0.5 0.5 0.5 0.8 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.6 22.0 2.9 13.3 17.8 11.4 11.1 33.6 36.5 26.8 24.7 24.3 14.0 19.6 13.7 52.5 21.5 9.3 29.8 19.1 20.3 17.0 11.4 12.6 22.0 5.5 14.9 23.4 8.8 8.5 36.5 11.0 12.0 2.2 9.8 22.3 21.5 7.4 14.2 8.4 12.6 15.5 18.9 14.5 15.1 22.9 8.0 2.8 12.4 13.4 23.3 6.7 5.1 10.9 25.5 20.8 27.2 21.6 12.3 6.2 25.2 24.6 12.9 13.1 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavourable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 18.8 14.3 30.7 14.6 29.1 52.3 38.6 24.0 19.8 21.5 17.8 23.7 25.1 27.5 20.9 35.9 7.8 9.7 21.1 21.5 36.8 6.6 20.6 10.8 61.8 24.6 9.8 0.9 46.9 9.7 53.0 23.7 55.8 13.3 0.0 56.4 10.3 22.7 6.1 15.6 22.8 27.5 21.0 0.1 14.3 6.6 12.0 20.0 16.5 0.0 17.9 3.9 17.8 70.1 42.7 18.3 12.3 28.5 0.0 0.0 16.7 27.5 12.5 31.2 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857362-113863471 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 74.3;TIME: 58.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 10.1;neutrophil: 15.0" "Group enriched" "Detected in many" 10 "B-cells: 3.9;granulocytes: 15.0;monocytes: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" 17000000 "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: , HPA067595: , HPA069443: " "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavourable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavourable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 13.0 5.0 11.2 17.0 12.9 26.9 16.0 18.5 43.3 12.1 23.2 17.9 0.9 11.6 9.7 4.0 17.0 8.4 10.9 9.7 10.5 5.3 8.7 12.9 13.3 8.8 15.9 12.6 11.2 1.2 6.5 39.5 13.8 14.1 21.6 11.4 8.2 5.6 5.0 9.5 12.9 9.1 42.3 20.9 18.8 5.2 8.5 30.0 4.9 7.9 13.6 23.5 7.8 3.9 0.9 15.0 10.1 0.0 0.0 0.4 6.8 4.0 74.3 4.0 25.1 16.4 0.4 22.0 31.0 15.6 26.1 7.2 9.7 0.0 4.6 40.6 21.2 12.2 6.4 20.3 0.0 7.3 0.0 4.3 9.3 16.7 1.7 0.1 16.9 12.6 15.0 14.3 43.9 0.8 19.6 22.1 0.0 0.2 0.0 9.6 5.3 0.0 7.4 0.7 4.9 13.1 10.3 30.1 14.1 7.2 15.1 0.3 2.0 58.3 14.5 0.0 23.7 37.5 53.0 3.8 2.0 11.1 9.8 27.7 0.0 3.4 0.0 0.0 10.1 0.0 3.9 0.0 0.0 0.9 1.6 0.0 0.0 15.0 0.0 5.5 0.0 0.0 0.4 MARS "CMT2U, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol 21000 Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavourable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavourable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavourable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" 23.8 26.7 35.1 27.3 29.1 23.0 19.8 25.1 36.0 17.4 23.9 23.1 23.9 17.3 23.3 36.3 29.5 17.9 16.1 25.0 28.0 29.5 20.5 45.9 24.3 25.1 40.1 25.5 25.8 48.3 35.7 34.0 22.2 30.9 25.6 24.7 19.8 26.0 30.0 24.5 18.4 20.1 33.7 30.7 30.7 31.3 29.6 30.9 21.4 26.9 22.3 34.3 24.3 27.9 12.9 29.3 19.0 27.0 14.1 18.9 15.5 16.5 23.0 15.4 26.7 17.3 10.5 28.4 23.7 27.8 25.1 26.9 24.7 18.4 29.1 15.7 28.7 18.8 35.1 30.6 26.3 25.2 15.2 20.5 8.6 13.9 38.5 30.9 23.6 15.3 47.6 28.7 74.4 17.9 31.7 62.4 17.4 22.9 27.6 23.3 29.1 25.4 24.0 116.3 30.1 18.9 13.0 20.6 20.9 12.3 18.9 32.8 25.0 40.5 13.2 9.1 26.9 13.1 14.0 57.2 57.8 35.1 22.3 23.5 31.0 12.1 14.6 19.0 18.9 27.0 17.2 12.9 12.9 17.1 29.3 7.7 11.1 15.2 7.2 14.1 21.8 28.4 13.1 15.5 35.1 29.1 25.1 36.0 28.0 29.5 40.1 25.5 30.9 30.9 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavourable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favourable (2.12e-4)" "unprognostic (6.03e-2)" 33.4 25.5 31.3 31.5 38.6 68.7 25.8 59.0 38.2 34.6 29.4 37.2 26.3 31.5 34.3 24.0 47.6 38.2 27.9 30.1 29.9 28.4 26.3 21.8 31.4 43.4 37.1 21.6 39.7 20.0 17.4 23.7 30.2 32.7 31.9 25.0 26.8 33.6 37.7 27.8 32.1 40.2 30.7 34.8 42.9 24.8 15.7 40.9 41.3 30.2 22.5 40.7 35.1 40.7 18.7 19.1 87.5 23.6 19.2 30.0 44.8 28.3 11.1 6.8 11.0 18.0 14.1 8.9 10.0 15.3 12.5 15.4 7.1 19.9 23.6 8.4 12.0 14.1 17.1 13.9 9.4 23.8 10.4 36.7 7.3 7.8 21.1 13.8 92.4 16.8 9.9 11.5 12.7 13.8 17.2 9.6 12.6 15.7 31.9 47.6 9.1 18.2 18.1 10.8 10.6 11.5 9.5 14.7 9.6 13.1 14.0 12.8 13.7 17.7 17.2 11.5 13.9 10.6 8.0 11.8 10.0 14.9 14.3 13.3 11.4 87.5 23.6 80.6 21.7 20.1 23.7 18.7 25.4 22.1 19.1 17.6 26.6 22.3 49.5 19.2 17.4 18.3 30.0 44.8 31.3 38.6 59.0 38.2 29.9 28.4 37.1 21.6 32.7 40.9 MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692131-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.0" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria 1400000 Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavourable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favourable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" 8.2 6.5 6.3 9.4 6.1 12.3 9.8 41.0 6.8 7.0 19.8 4.1 8.5 19.1 10.9 7.4 13.4 7.8 11.5 6.9 4.8 4.3 11.1 7.2 10.1 7.4 3.4 4.1 5.8 12.1 8.2 5.5 8.8 5.5 4.6 21.9 5.1 9.5 5.8 41.4 9.0 23.0 11.0 3.8 4.9 29.4 4.7 3.5 4.9 5.4 14.9 7.3 10.1 15.0 3.4 5.4 16.6 7.6 1.9 4.6 3.6 19.7 32.0 8.3 6.0 12.7 14.3 8.5 12.2 17.4 12.2 13.0 19.0 18.9 8.4 9.8 14.8 18.0 10.9 14.5 16.3 9.2 10.2 10.5 12.0 10.5 9.9 26.3 8.9 14.5 12.3 10.9 23.4 14.6 6.5 6.3 11.3 11.4 7.1 5.7 9.1 6.7 7.4 17.8 2.2 16.5 10.8 8.9 3.9 15.0 16.8 3.6 3.3 6.9 11.8 5.9 10.2 12.7 8.1 4.7 5.9 5.9 7.9 13.2 4.5 1.7 6.1 16.6 2.9 6.7 3.1 3.4 3.0 3.5 5.4 1.7 2.3 2.6 8.2 1.9 7.6 1.9 4.6 3.6 6.3 6.1 41.0 6.8 4.8 4.3 3.4 4.1 5.5 3.5 MIDN ENSG00000167470 Midnolin Q504T8 19 1248553-1259140 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "neutrophil: 13.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042018, HPA049432" Uncertain Approved Nucleoplasm Nucleoplasm "HPA042018: , HPA049432: " "unprognostic (1.82e-2)" "unprognostic (6.21e-2)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (1.06e-2)" "unprognostic (2.04e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-1)" "unprognostic (3.56e-1)" "unprognostic (1.19e-2)" 28.0 32.6 9.7 22.7 16.1 59.4 16.6 8.9 19.5 19.5 24.7 17.6 12.6 19.0 14.1 14.2 38.7 28.3 40.8 27.8 10.4 9.8 17.9 19.3 28.7 19.9 10.2 6.5 36.7 20.0 8.2 32.7 19.7 22.3 20.1 11.1 19.5 18.8 22.2 48.2 26.6 31.6 14.6 14.6 30.7 21.9 10.5 9.2 28.6 14.0 31.3 34.5 19.4 20.1 0.4 0.5 13.5 1.2 1.4 1.2 0.6 5.1 11.4 19.6 9.1 4.2 7.1 14.4 8.9 5.4 4.6 3.2 14.8 5.8 8.2 9.8 6.7 10.6 5.9 9.5 1.8 11.5 10.8 11.5 7.4 11.6 8.5 11.5 17.2 11.0 9.0 5.5 5.3 7.5 14.7 8.7 4.8 20.6 15.4 4.7 42.9 7.6 24.1 5.5 3.7 8.6 6.1 15.7 20.5 18.9 18.2 11.8 7.3 13.3 9.3 8.4 9.4 38.8 9.6 8.2 4.4 11.2 16.2 5.2 28.7 1.1 1.2 1.2 1.2 1.2 0.8 0.3 0.4 0.8 0.5 0.4 0.2 0.6 13.5 1.4 1.2 0.5 0.1 0.6 9.7 16.1 8.9 15.5 10.4 9.8 10.2 6.5 22.3 9.2 MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916729-167937040 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 111.7" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain "HPA056091: " "unprognostic (3.25e-1)" "unprognostic (6.82e-2)" "unprognostic (8.79e-3)" "unprognostic (4.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-3)" "unprognostic (1.44e-3)" "unprognostic (1.08e-2)" "unprognostic (9.13e-2)" "unprognostic (2.39e-1)" "unprognostic (6.95e-2)" "unprognostic (5.43e-2)" "unprognostic (1.67e-1)" 13.5 22.5 22.6 11.5 21.6 33.5 23.0 15.0 25.3 11.7 26.8 12.1 10.2 27.1 7.8 12.5 12.2 9.9 25.2 46.2 19.0 17.7 46.4 92.9 9.9 11.4 18.8 16.7 9.6 14.7 9.6 18.4 9.9 13.5 34.4 24.8 11.9 20.6 10.8 45.0 9.3 26.3 13.1 16.5 7.4 29.6 111.7 11.4 12.7 11.9 23.5 10.9 11.2 8.1 23.4 28.7 45.3 18.5 27.4 40.2 37.2 18.2 17.5 7.7 17.5 19.3 17.9 1.7 29.9 16.8 14.1 16.5 40.5 10.2 31.7 21.7 17.0 14.8 10.4 16.1 14.6 40.5 15.6 13.8 17.8 32.1 13.0 14.9 10.2 11.5 14.8 25.3 14.6 12.3 17.0 18.6 25.1 8.4 22.0 15.3 12.8 21.9 11.6 14.1 25.1 93.5 15.9 12.3 12.5 17.2 20.4 16.4 36.7 19.2 11.3 15.2 11.2 22.1 13.7 24.7 28.1 34.8 39.0 13.5 8.0 41.0 16.6 45.3 23.7 14.6 25.3 23.4 29.3 25.0 28.7 20.6 27.7 26.5 31.8 27.4 18.5 20.7 40.2 37.2 22.6 21.6 15.0 25.3 19.0 17.7 18.8 16.7 13.5 11.4 MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055697-190062729 "Disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 17.2;tongue: 15.8" "Group enriched" "Detected in some" 12 "LHCN-M2: 15.9;RH-30: 32.3" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" 4800000 "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favourable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" 3.3 1.9 1.7 0.7 1.4 0.2 0.8 4.1 1.8 4.8 1.1 2.2 0.0 0.7 1.8 1.2 2.3 0.5 0.6 0.7 3.5 1.6 1.1 0.3 0.3 0.3 1.3 0.0 0.7 0.4 0.4 1.4 0.2 3.4 1.0 1.1 0.9 1.0 0.5 17.2 1.2 2.1 0.9 1.1 0.3 0.6 0.7 4.0 0.0 0.7 15.8 0.4 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 4.1 1.0 3.5 1.6 1.3 0.0 3.4 4.0 MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969720-92985066 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;lymphoid tissue: 1.9;placenta: 4.5;testis: 2.0" "Group enriched" "Detected in some" 8 "AF22: 1.1;U-138 MG: 1.4;WM-115: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "midbrain: 0.8;pons and medulla: 1.2" HPA074024 Supported "HPA074024: " "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" 0.1 0.0 0.3 0.0 3.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127741434 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 129.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: , HPA066556: " "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavourable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavourable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavourable (4.96e-5)" 67.4 20.8 3.2 46.6 7.1 16.3 36.0 1.2 5.0 23.9 23.3 3.8 11.8 11.1 23.8 14.4 47.6 59.5 32.4 23.7 5.8 2.2 11.2 36.6 16.0 40.5 5.8 1.2 38.7 64.6 2.1 7.4 14.9 9.8 20.6 11.3 6.1 14.4 21.8 69.6 78.5 17.2 21.3 12.0 38.3 24.7 16.3 3.8 40.2 9.0 48.4 27.1 28.9 37.3 25.5 8.8 1.0 10.3 20.9 55.2 22.0 7.1 13.8 1.2 12.3 20.0 23.7 3.6 8.6 3.7 10.7 9.0 18.8 18.7 72.9 12.0 5.1 15.5 63.9 27.8 7.1 17.2 22.3 43.9 23.4 24.5 18.4 30.7 7.0 16.5 61.5 7.2 57.0 12.3 64.8 38.6 5.3 20.5 50.1 66.8 3.4 27.6 27.9 5.2 129.7 9.0 7.4 84.9 8.0 4.0 33.5 22.2 13.6 20.2 14.9 8.1 9.6 6.2 10.7 0.7 1.2 35.2 7.1 34.3 4.0 0.7 10.3 0.1 8.6 9.1 43.4 25.5 31.1 18.6 8.8 20.6 55.2 34.8 1.0 20.9 6.1 0.3 24.8 22.0 3.2 7.1 1.2 3.6 5.8 2.2 5.8 1.2 9.8 3.8 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492812 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" 30000 "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: " "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 61.5 8.6 3.3 20.1 4.1 0.9 45.7 4.4 4.3 33.8 35.5 5.3 17.2 14.0 36.0 20.5 34.3 20.3 38.2 29.3 3.3 2.5 24.8 24.8 30.3 13.4 3.3 3.8 23.7 44.8 8.6 7.6 32.2 6.1 27.4 12.7 20.0 44.5 19.0 20.0 17.1 29.9 40.8 3.6 12.3 24.2 12.6 2.9 9.4 23.0 21.3 18.6 32.0 32.4 7.9 1.7 0.8 3.1 0.0 3.5 2.2 35.5 39.1 4.2 17.3 19.9 19.8 16.3 36.3 30.2 24.0 20.2 26.0 19.6 3.5 26.3 55.9 30.2 6.3 25.2 12.5 15.8 16.0 3.4 21.3 9.5 29.6 0.3 18.0 15.4 12.6 22.0 12.7 30.8 2.7 3.0 20.3 27.1 0.4 0.2 2.7 7.2 1.4 5.8 6.4 22.0 18.6 1.7 9.5 22.8 33.4 14.6 27.3 1.8 40.4 34.8 26.8 17.0 31.3 2.3 1.8 1.5 27.7 0.8 30.1 0.2 1.3 0.0 1.5 3.1 0.8 7.9 3.5 1.6 1.7 6.7 1.3 0.7 0.8 0.0 2.6 1.6 3.0 2.2 3.3 4.1 4.4 4.3 3.3 2.5 3.3 3.8 6.1 2.9 MYRIP "DKFZp586F1018, exophilin-8, MyRIP, SLAC2-C, SLAC2C" ENSG00000170011 "Myosin VIIA and Rab interacting protein" Q8NFW9 3 39808914-40260321 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;retina: 36.3" "Cell line enhanced" "Detected in some" "HAP1: 4.4;HUVEC TERT2: 16.6;REH: 3.9;SCLC-21H: 3.5;SH-SY5Y: 10.3;T-47d: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006433 Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "HPA006433: AB_10603023" "unprognostic (1.87e-2)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.89e-2)" "unprognostic (2.36e-1)" "unprognostic (6.03e-2)" "unprognostic (2.57e-3)" "unprognostic (1.34e-3)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (1.91e-1)" "prognostic favourable (3.96e-8)" "unprognostic (7.12e-2)" "unprognostic (2.40e-1)" "unprognostic (8.92e-2)" "unprognostic (6.16e-2)" 4.8 2.0 31.0 2.2 7.8 0.5 3.4 23.7 19.4 9.0 4.2 3.9 1.3 2.9 6.0 3.8 2.4 3.3 4.3 2.8 13.9 9.6 2.7 16.7 1.7 2.6 8.5 11.0 5.3 13.1 2.1 8.4 0.6 10.8 3.4 4.4 36.3 16.0 1.8 2.7 1.8 2.8 3.9 5.5 10.2 7.7 1.7 4.2 0.0 2.1 1.6 2.9 2.8 2.7 0.8 0.1 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.3 0.2 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 16.6 0.0 0.1 0.2 0.1 0.0 0.0 1.1 0.1 3.9 0.0 0.0 0.4 2.1 3.5 10.3 0.0 0.0 0.0 4.1 0.0 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.0 31.0 7.8 23.7 18.4 13.9 9.6 8.5 11.0 10.8 4.2 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387480-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 97.7;lymphoid tissue: 152.6" "Group enriched" "Detected in some" 5 "Karpas-707: 64.6;RPMI-8226: 228.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 29.5;plasmacytoid DC: 97.7" "Group enriched" "Detected in many" 115 "B-cells: 29.5;dendritic cells: 97.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced "Secreted to blood" 670000 "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favourable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favourable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavourable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 2.2 1.9 0.6 37.8 0.6 6.2 4.4 0.5 0.6 5.7 25.5 0.4 0.3 21.6 1.2 0.6 13.6 2.9 5.6 0.8 0.6 0.6 4.2 2.6 6.7 54.7 0.6 0.3 1.7 2.1 0.0 0.8 0.4 0.4 2.4 9.8 2.0 30.2 7.1 0.7 0.7 13.3 0.5 0.6 92.6 15.0 3.7 0.3 152.6 3.3 3.1 54.3 26.6 2.0 29.5 97.7 0.5 0.0 0.3 0.5 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.0 25.0 0.2 0.0 0.0 10.3 0.0 228.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 31.0 1.7 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 29.5 0.1 0.1 0.0 11.0 0.0 0.0 0.5 0.3 0.0 97.7 0.0 4.5 0.6 0.6 0.5 0.6 0.6 0.6 0.6 0.3 0.4 0.3 NCK1 "NCK, NCKalpha" ENSG00000158092 "NCK adaptor protein 1" P16333 3 136862208-136949823 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005063, HPA030766" Supported Enhanced "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB005063: AB_562169, HPA030766: " "unprognostic (7.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.98e-2)" "unprognostic (3.03e-2)" "unprognostic (1.06e-2)" "unprognostic (8.77e-3)" "unprognostic (4.24e-3)" "unprognostic (8.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.22e-1)" "prognostic unfavourable (9.14e-5)" "unprognostic (5.96e-2)" "prognostic unfavourable (1.08e-4)" "unprognostic (1.64e-1)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (4.17e-2)" 44.5 15.7 11.5 24.5 13.4 19.3 38.9 22.6 11.6 23.7 18.3 8.4 16.5 10.2 20.8 19.2 35.9 14.6 13.9 16.8 11.8 11.1 14.0 20.9 22.4 33.0 13.9 12.1 19.6 14.3 17.9 17.7 22.7 13.5 26.3 19.5 10.8 24.0 15.8 29.0 27.3 14.3 24.0 13.5 18.7 12.8 14.7 12.7 41.1 23.8 23.5 29.0 27.3 43.3 8.5 13.3 26.8 27.1 11.2 20.2 11.9 19.6 8.7 11.5 9.5 26.8 26.1 12.9 14.5 26.2 16.9 17.7 12.7 19.6 19.3 30.2 17.0 15.2 16.2 14.8 22.6 13.9 6.6 16.7 12.4 9.9 43.7 12.1 11.6 23.6 19.5 16.4 32.8 25.9 10.0 17.3 17.7 10.7 27.3 9.7 11.0 11.1 14.9 10.8 18.5 15.8 13.5 8.2 8.0 26.2 11.8 23.4 16.9 13.3 12.8 11.0 7.2 15.6 8.3 17.3 13.6 23.9 11.7 10.9 11.7 26.8 12.4 13.2 19.7 27.1 20.2 8.1 15.6 19.8 13.3 8.5 12.6 15.0 7.2 11.2 13.4 5.2 15.0 11.9 11.5 13.4 22.6 11.6 11.8 11.1 13.9 12.1 13.5 12.7 NCOA5 "bA465L10.6, CIA" ENSG00000124160 "Nuclear receptor coactivator 5" Q9HCD5 20 46060985-46089952 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050231 Uncertain Supported "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA050231: " "unprognostic (1.78e-1)" "unprognostic (1.54e-1)" "unprognostic (2.43e-2)" "unprognostic (7.93e-2)" "unprognostic (2.30e-1)" "unprognostic (1.43e-2)" "prognostic unfavourable (1.41e-5)" "prognostic favourable (8.07e-4)" "unprognostic (2.32e-1)" "unprognostic (7.75e-2)" "prognostic favourable (1.09e-4)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.07e-1)" "unprognostic (8.78e-2)" "unprognostic (1.91e-2)" 16.0 15.0 20.9 25.8 18.5 8.1 55.1 31.2 25.6 19.3 17.7 12.0 18.5 14.0 23.4 20.3 16.5 21.1 15.8 13.8 19.3 13.1 14.1 12.9 21.7 23.0 14.6 16.2 29.8 27.0 23.4 26.2 18.4 15.7 19.2 16.5 14.7 18.5 23.6 22.8 19.4 18.1 19.8 13.6 23.3 16.5 44.4 16.7 23.8 19.2 14.2 23.8 18.2 42.5 17.4 18.5 10.7 8.6 7.4 14.0 5.4 19.2 17.1 24.2 24.8 11.6 12.3 19.4 13.4 12.1 21.8 17.9 23.6 15.4 31.6 22.7 12.9 25.8 19.9 16.7 18.8 19.1 10.0 18.9 17.0 19.9 12.3 26.0 18.5 8.8 22.4 11.5 10.5 15.4 17.6 25.8 17.1 24.9 35.7 20.1 22.0 21.1 27.2 16.0 13.8 12.8 21.9 21.8 19.7 21.4 26.2 18.7 20.8 30.7 14.3 23.1 17.5 13.8 20.7 16.9 23.8 21.3 16.0 15.3 14.6 3.3 8.3 10.7 12.2 8.5 14.0 11.6 12.8 12.3 8.3 17.4 12.3 11.1 6.0 7.4 8.6 18.5 8.2 5.4 20.9 18.5 31.2 25.6 19.3 13.1 14.6 16.2 15.7 16.7 NDEL1 "MITAP1, NDE1L1, NDE2, NUDEL" ENSG00000166579 "NudE neurodevelopment protein 1 like 1" Q9GZM8 17 8413131-8490411 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017916 Approved "HPA017916: AB_1854337" "unprognostic (6.34e-2)" "unprognostic (4.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-3)" "unprognostic (6.98e-3)" "unprognostic (1.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.77e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (4.66e-2)" "unprognostic (5.89e-2)" "unprognostic (6.73e-3)" "unprognostic (8.82e-2)" "unprognostic (1.01e-1)" "unprognostic (7.63e-3)" 25.8 41.9 20.6 23.3 31.3 62.3 18.4 23.4 34.2 19.2 16.6 17.3 15.7 12.0 19.7 14.2 30.8 16.9 27.1 17.4 19.2 20.1 11.8 28.7 24.4 16.4 16.4 27.2 27.3 17.9 15.1 25.0 29.6 31.2 16.1 15.7 12.6 18.4 16.2 25.7 49.2 13.9 18.0 17.0 17.1 15.0 18.9 15.2 11.9 14.0 27.5 20.6 20.5 23.9 8.1 7.0 52.5 8.3 9.1 11.6 9.7 14.8 13.3 12.7 10.8 19.3 23.8 10.4 31.8 26.6 22.8 24.1 11.5 8.1 8.6 10.8 35.1 17.4 11.3 12.5 23.6 14.2 18.4 17.2 19.9 13.7 20.7 6.4 36.7 15.6 24.8 19.6 22.5 18.2 10.1 10.2 19.9 6.3 9.5 5.5 5.5 7.5 10.0 10.0 7.0 10.3 8.5 6.0 6.6 19.2 9.4 10.4 6.3 4.5 23.8 18.2 6.9 16.8 17.3 7.1 14.6 7.1 22.8 9.8 18.4 21.2 8.3 27.9 11.1 8.0 11.6 8.1 10.0 10.9 7.0 8.0 9.9 8.9 52.5 9.1 6.8 6.2 10.4 9.7 20.6 31.3 23.4 34.2 19.2 20.1 16.4 27.2 31.2 15.2 NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945129-61153037 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048082, HPA054776" Supported Enhanced Mitochondria Mitochondria "HPA048082: AB_2680254, HPA054776: AB_2682598" "unprognostic (7.28e-2)" "unprognostic (6.83e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-2)" "prognostic unfavourable (2.56e-4)" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (8.40e-3)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "prognostic unfavourable (2.49e-4)" "unprognostic (1.79e-2)" "unprognostic (6.10e-2)" "unprognostic (2.37e-1)" "unprognostic (4.66e-2)" 25.5 25.9 22.5 16.7 24.9 11.4 27.1 13.6 24.4 16.9 20.5 11.7 8.2 16.0 16.3 12.2 19.3 12.6 15.0 33.6 19.9 21.2 19.1 27.2 11.9 13.4 20.5 14.2 23.5 41.2 14.2 25.3 9.8 18.5 19.0 18.2 13.2 16.0 16.8 56.3 12.9 13.3 23.9 18.3 10.0 17.2 20.1 12.6 4.9 17.7 16.0 12.3 26.9 19.5 15.9 20.9 1.5 13.1 17.3 20.3 9.1 31.0 16.4 11.3 36.5 22.1 31.3 21.4 36.4 19.4 23.1 28.4 27.3 22.5 39.1 37.7 24.7 12.9 19.4 31.8 28.7 20.7 27.8 13.5 29.3 25.5 33.3 19.5 8.0 16.9 34.4 21.0 63.9 20.6 22.2 20.9 24.1 24.6 17.3 28.8 9.4 39.0 19.1 31.2 53.0 22.0 13.4 23.9 10.7 22.7 19.7 35.3 23.5 13.8 19.1 16.7 25.4 35.8 40.2 15.3 22.0 43.0 22.1 35.1 19.3 0.0 13.1 1.5 12.5 11.9 14.3 15.9 15.9 14.6 20.9 11.0 13.9 14.3 0.6 17.3 9.1 7.5 20.3 9.1 22.5 24.9 13.6 24.4 19.9 21.2 20.5 14.2 18.5 12.6 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515017 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "RH-30: 54.7;WM-115: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "plasmacytoid DC: 4.2" "Lineage enriched" "Detected in single" 7 "dendritic cells: 4.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 13.1;hypothalamus: 8.2;pons and medulla: 3.7" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" 100000 Nucleoplasm "Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavourable (3.40e-4)" 30.9 24.0 1.2 9.2 7.4 1.0 11.7 6.1 4.5 7.6 9.4 10.4 7.9 3.2 6.8 15.0 11.3 12.6 10.8 22.2 2.4 2.9 4.8 29.1 1.4 11.6 13.8 1.3 7.6 6.2 2.8 6.7 16.7 15.9 17.7 3.4 20.2 17.2 9.7 4.8 8.4 5.0 10.7 22.4 18.9 4.9 12.2 4.4 0.4 25.8 7.4 7.0 13.1 6.8 0.0 4.2 0.0 0.4 0.0 0.5 0.2 0.0 0.0 1.7 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.4 1.2 0.0 0.1 0.2 0.1 0.0 1.0 0.1 0.0 0.1 5.8 0.0 0.1 0.4 0.0 0.0 0.0 7.9 0.1 0.0 0.0 1.0 0.0 1.0 54.7 0.0 0.0 0.0 0.5 0.3 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.9 0.1 2.7 0.0 0.0 0.0 0.0 0.5 60.7 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.2 0.0 0.2 1.2 7.4 6.1 4.0 2.4 2.9 13.8 1.3 15.9 4.4 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493071 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favourable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 16.5 24.9 29.7 14.3 36.1 18.1 16.7 84.5 47.5 24.1 16.4 21.4 22.1 12.9 24.4 19.5 14.1 20.9 16.4 14.1 24.7 18.8 14.9 11.8 17.1 15.9 13.2 35.6 30.7 21.8 23.3 55.3 21.0 20.8 29.8 11.4 27.0 26.5 30.2 12.2 42.5 14.8 20.9 13.3 16.8 14.8 27.3 13.9 16.3 17.1 7.8 12.6 21.9 19.5 5.8 6.6 6.5 8.3 6.1 8.1 6.4 7.5 8.0 24.9 20.3 18.6 20.7 20.5 16.4 10.9 13.2 13.5 11.9 11.5 10.6 4.6 22.7 10.2 13.2 17.9 7.8 10.8 14.2 19.2 27.9 11.6 17.0 11.2 17.2 32.4 14.4 14.2 12.1 21.2 10.1 11.9 12.3 10.8 20.1 25.0 15.2 13.7 12.0 6.8 12.4 15.0 15.2 10.5 18.4 17.8 4.7 11.4 14.7 19.0 23.1 18.6 17.8 18.8 11.7 19.8 11.3 13.5 12.8 18.4 11.3 6.3 8.3 6.5 6.4 7.6 6.3 4.7 5.4 8.1 4.5 5.8 6.5 6.5 2.9 6.1 1.1 6.6 5.8 6.4 29.7 36.1 84.5 47.5 24.7 18.8 13.2 35.6 20.8 13.9 NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.0" "Cell line enhanced" "Detected in many" "AF22: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria Mitochondria "HPA055321: , HPA069278: " "unprognostic (1.31e-1)" "unprognostic (1.87e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.23e-2)" "prognostic unfavourable (3.44e-4)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-3)" "unprognostic (1.81e-2)" 13.0 10.9 31.3 9.9 45.3 2.4 7.4 32.7 47.0 16.9 11.3 18.3 9.5 4.4 25.3 16.4 9.0 13.8 15.5 6.6 28.8 16.0 5.7 3.3 6.2 6.1 13.9 27.5 24.3 7.4 20.7 8.3 8.5 21.3 11.6 5.9 11.2 6.5 19.2 6.3 8.7 5.4 24.3 19.4 7.5 5.9 4.8 15.9 0.0 4.8 1.7 5.0 9.8 11.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 4.2 6.0 26.4 15.2 8.1 11.3 0.6 7.1 11.2 12.1 11.1 1.3 1.5 0.0 3.5 9.8 2.4 4.9 2.9 6.5 6.4 4.9 1.8 5.4 1.0 4.1 1.8 6.5 9.1 2.4 9.9 1.6 4.1 1.7 3.4 5.0 4.0 0.8 1.8 4.5 2.8 7.6 3.2 0.8 3.5 0.9 0.4 10.6 3.3 1.5 1.8 4.3 0.2 5.6 10.4 13.3 6.5 3.4 4.0 1.3 0.7 10.8 1.7 3.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 31.3 45.3 32.7 37.2 28.8 16.0 13.9 27.5 21.3 15.9 NNAT Peg5 ENSG00000053438 Neuronatin Q16517 20 37521215-37523693 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "brain: 117.2;pituitary gland: 165.1;placenta: 69.1" "Cell line enriched" "Detected in some" 22 "SH-SY5Y: 124.5" "Group enriched" "Detected in many" 16 "glioma: 87.5;testis cancer: 55.0;urothelial cancer: 37.4" "Region enhanced" "Detected in all" "basal ganglia: 117.2" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "unprognostic (1.18e-2)" "unprognostic (7.41e-3)" "unprognostic (1.85e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (9.66e-4)" "unprognostic (7.08e-2)" "unprognostic (1.42e-1)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (7.52e-2)" "unprognostic (4.94e-2)" "unprognostic (1.64e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.15e-3)" "unprognostic (5.90e-2)" 17.0 11.6 35.4 2.6 117.2 2.3 3.5 4.9 68.4 2.3 7.0 11.1 0.0 3.4 4.6 2.5 2.6 2.8 4.2 1.7 35.0 21.4 1.4 1.1 1.7 1.9 4.9 14.0 1.3 1.6 1.0 165.1 69.1 7.9 2.4 3.9 1.5 3.4 1.5 8.0 3.8 3.2 4.4 2.1 1.8 2.1 2.9 3.8 0.2 1.5 0.0 1.1 3.3 0.6 0.7 0.7 0.3 0.3 0.0 1.0 0.0 0.3 0.2 2.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.5 0.1 0.1 0.5 0.0 0.0 0.0 5.5 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.2 0.0 0.6 0.0 0.0 3.1 0.2 124.5 0.1 0.7 0.0 0.2 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 1.0 0.3 0.0 0.0 0.7 0.0 0.0 35.4 117.2 4.9 41.0 35.0 21.4 4.9 14.0 7.9 3.8 NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800499 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;lymphoid tissue: 15.6" "Group enriched" "Detected in some" 8 "CACO-2: 16.6;SCLC-21H: 13.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB002014 Enhanced "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" 1.0 0.7 1.6 15.6 1.6 0.0 0.5 1.5 7.3 0.4 6.8 0.0 0.0 11.8 0.4 0.0 1.0 0.5 0.4 0.7 1.3 1.1 1.7 0.2 3.8 1.8 1.0 2.2 1.0 0.3 0.1 2.1 3.4 0.4 0.9 9.0 1.2 0.2 0.2 0.7 0.4 20.8 1.7 0.8 0.2 0.3 0.4 0.2 0.2 0.5 5.3 1.7 5.4 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.6 1.5 7.3 1.3 1.1 1.0 2.2 0.4 0.2 NPFF FMRFAL ENSG00000139574 "Neuropeptide FF-amide peptide precursor" O15130 12 53506690-53507638 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 28 "epididymis: 154.7" "Cell line enriched" "Detected in some" 7 "HHSteC: 17.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebellum: 2.0;hypothalamus: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "pons and medulla: 11.9" "Region enriched" "Detected in all" 8 "cerebellum: 143.2" "Secreted in male reproductive system" 0.3 0.1 0.1 0.1 0.3 0.0 0.1 2.0 0.1 0.5 0.2 0.1 1.1 0.2 0.1 154.7 0.1 0.2 0.1 0.1 0.1 1.4 0.1 0.1 0.5 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.5 0.2 0.1 1.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.7 0.2 0.8 0.2 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.1 1.9 0.4 0.8 0.2 0.0 0.3 0.2 0.5 1.9 0.1 0.0 0.2 0.0 0.2 2.4 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 2.0 0.1 0.1 1.4 0.1 0.1 0.3 0.1 NPPA "ANP, PND" ENSG00000175206 "Natriuretic peptide A" P01160 1 11845709-11848345 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hormone, Vasoactive" "Atrial fibrillation, Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 418 "heart muscle: 1267.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 12.2;SH-SY5Y: 11.7" "Cancer enriched" "Detected in some" 9 "glioma: 7.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in some" 8 "olfactory region: 28.1" "Region enriched" "Detected in some" 5 "olfactory region: 21.2" HPA058269 Enhanced "Secreted to blood" 190000 "HPA058269: " "unprognostic (1.27e-3)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.72e-3)" "unprognostic (2.21e-1)" "unprognostic (5.93e-4)" "unprognostic (2.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 1267.7 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 1.7 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.3 0.0 0.3 0.8 0.0 0.5 3.0 1.1 1.6 2.6 2.1 0.0 0.0 1.6 0.9 0.0 0.0 0.0 6.5 2.6 4.2 0.3 0.0 4.0 0.0 0.0 0.0 1.0 2.6 2.7 1.5 6.4 0.0 1.4 4.5 0.0 0.0 0.0 0.0 0.0 5.8 5.0 0.0 0.9 0.5 7.5 1.9 0.7 0.6 0.8 0.8 0.0 1.8 12.2 11.7 0.7 0.0 2.2 1.6 0.2 0.4 2.1 4.2 3.4 0.3 1.3 3.1 4.8 0.2 3.4 1.1 0.0 0.4 0.0 0.1 0.8 0.4 1.3 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.5 0.0 0.0 3.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913966 "Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 47.2;liver: 49.4;pancreas: 52.8" "Cell line enriched" "Detected in some" 32 "Hep G2: 40.9" "Group enriched" "Detected in many" 5 "liver cancer: 52.3;stomach cancer: 11.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 6 "cerebellum: 1.9" "Low region specificity" "Detected in all" "unprognostic (2.99e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-3)" "unprognostic (9.21e-2)" "unprognostic (8.22e-2)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (2.11e-2)" "unprognostic (6.74e-3)" "unprognostic (1.04e-1)" "unprognostic (2.03e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" 0.1 7.5 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.1 11.8 0.3 0.1 32.6 0.1 0.8 0.1 0.0 18.5 16.6 0.1 0.0 9.3 49.4 2.4 0.1 0.1 0.1 0.1 52.8 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 3.5 0.0 47.2 0.1 0.1 5.3 8.5 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.1 1.0 0.6 0.0 0.4 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 40.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.2 0.1 NR1D1 "ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092787-40100725 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 16.3" "Group enriched" "Detected in many" 6 "monocytes: 4.2;T-cells: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavourable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favourable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 19.4 15.1 12.2 7.6 14.7 6.0 30.5 30.7 32.5 45.9 13.9 6.4 17.3 15.2 16.5 6.1 16.8 10.7 8.2 43.7 8.8 5.2 9.8 14.8 12.7 8.8 4.7 11.7 33.3 8.3 4.8 10.9 7.3 6.1 15.5 5.5 28.0 53.0 18.6 51.2 79.3 8.8 27.3 6.0 7.8 7.9 7.3 6.8 1.8 13.9 11.7 10.6 28.0 25.4 1.8 1.1 0.1 4.2 0.8 16.3 1.5 2.8 4.1 0.8 3.3 4.9 3.4 1.2 6.3 10.3 2.1 2.6 2.7 10.3 3.4 3.8 7.2 8.1 2.2 9.4 1.5 2.9 2.3 2.5 4.1 6.9 8.0 3.7 3.7 7.4 6.8 7.1 15.2 2.6 3.7 32.2 2.0 2.0 5.5 3.3 1.6 6.5 3.9 1.3 10.6 2.8 2.6 2.8 1.6 3.9 5.2 6.4 2.5 3.1 2.5 9.3 9.2 7.6 4.9 11.7 17.8 1.4 12.6 2.1 7.1 0.0 0.4 0.0 3.9 1.6 16.3 1.5 4.9 5.7 0.9 1.8 4.5 3.2 0.1 0.8 4.2 1.1 6.5 1.5 12.2 14.7 30.7 32.5 8.8 5.2 4.7 11.7 6.1 6.8 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918505-51225575 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 81.9" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 28.3" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "neutrophil: 4.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" 620000 "Plasma membrane" "HPA071400: " "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 2.1 3.2 22.4 2.1 20.3 1.4 1.7 56.5 81.9 2.8 5.1 3.0 0.5 2.1 2.1 3.7 3.0 1.4 2.2 3.8 16.9 13.8 1.5 1.6 1.5 1.4 8.3 25.9 2.1 2.3 1.3 4.8 1.1 12.6 2.5 3.8 2.0 3.5 9.3 1.3 2.0 3.1 2.1 6.5 1.3 2.3 6.5 4.7 0.0 1.4 0.0 1.4 2.0 1.6 0.0 0.0 4.4 0.1 0.3 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.2 0.0 0.0 28.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 2.4 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.3 0.0 0.0 0.0 0.0 22.4 20.3 56.5 33.2 16.9 13.8 8.3 25.9 12.6 4.7 NSMCE2 "C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7" ENSG00000156831 "NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase" Q96MF7 8 125091679-125367120 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Ubl conjugation pathway" Transferase "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051614, HPA065734" Supported Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA051614: , HPA065734: " "unprognostic (1.14e-3)" "unprognostic (1.29e-1)" "unprognostic (6.56e-2)" "unprognostic (1.22e-3)" "unprognostic (8.65e-2)" "unprognostic (8.89e-3)" "prognostic unfavourable (7.54e-4)" "unprognostic (3.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.53e-2)" "unprognostic (1.33e-1)" "unprognostic (3.09e-2)" "unprognostic (1.17e-1)" "unprognostic (7.53e-2)" "unprognostic (2.61e-2)" "unprognostic (6.85e-2)" 22.4 22.3 17.6 16.4 20.2 26.2 23.8 21.0 22.6 18.2 19.9 17.1 17.6 12.3 28.3 19.5 18.6 14.3 16.5 22.9 13.7 12.7 18.5 17.2 16.3 19.4 20.2 17.3 21.3 14.9 11.2 32.0 19.1 16.1 15.0 17.8 16.7 19.3 17.4 36.5 18.1 13.4 21.9 18.3 16.6 18.9 19.1 20.6 18.5 18.2 16.8 24.9 18.8 21.2 12.6 12.6 35.3 12.6 11.1 18.8 12.5 16.1 14.0 16.7 10.5 13.2 20.0 8.1 13.0 24.5 23.1 26.9 8.9 15.5 20.3 15.3 12.3 12.1 13.0 10.9 23.6 22.7 12.7 28.6 8.5 12.9 19.1 8.5 8.7 14.7 15.3 13.3 17.0 20.8 16.5 13.4 20.1 27.9 21.9 7.9 3.7 18.8 12.3 11.6 18.3 13.9 12.3 11.1 11.8 15.5 46.8 21.6 19.9 9.8 12.9 8.9 25.3 11.0 18.4 17.9 31.9 25.5 13.9 16.6 13.8 5.1 12.6 35.3 12.2 10.9 13.5 12.6 13.0 13.7 12.6 11.5 13.4 14.6 6.1 11.1 10.9 7.4 18.8 12.5 17.6 20.2 21.0 22.6 13.7 12.7 20.2 17.3 16.1 20.6 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225716-53251697 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.0;prostate: 6.7" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: " "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.7 0.7 15.9 0.3 18.0 0.4 0.3 2.2 8.8 0.4 0.4 0.3 0.0 0.4 0.4 0.6 0.5 0.7 0.4 0.8 4.5 6.2 0.3 0.5 0.8 0.4 1.7 5.8 0.4 0.3 0.4 0.8 2.8 3.1 6.7 0.4 0.0 0.3 0.4 3.8 0.4 0.5 0.5 0.5 0.6 0.3 2.8 1.6 0.2 0.9 0.0 0.3 0.3 0.1 0.2 0.8 1.2 0.2 0.1 0.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 1.2 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 15.9 18.0 2.2 8.8 4.5 6.2 1.7 5.8 3.1 1.6 OTC ENSG00000036473 "Ornithine carbamoyltransferase" P00480 X 38352545-38421450 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "intestine: 59.1;liver: 90.3" "Cell line enhanced" "Detected in some" "NB-4: 1.8;RPMI-8226: 1.0;SH-SY5Y: 1.1;SiHa: 1.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 59.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000243, HPA000570" Enhanced Supported Mitochondria 1800000 Mitochondria "HPA000243: AB_1079535, HPA000570: AB_1079534" "unprognostic (6.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.89e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.70e-3)" "unprognostic (5.61e-2)" 0.4 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.1 0.8 16.5 0.0 0.2 26.9 1.1 0.2 0.2 0.3 5.3 0.2 0.1 0.2 0.1 90.3 0.7 2.3 0.2 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.1 0.1 59.1 0.8 0.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.6 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.0 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 108.8" "Cell line enhanced" "Detected in many" "HeLa: 56.1;SiHa: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" 1000000 Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favourable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 21.9 8.0 17.3 7.5 30.3 5.8 9.5 26.6 36.8 6.7 9.2 8.3 10.7 4.4 8.6 8.7 13.1 6.9 7.5 108.8 19.3 15.2 25.3 1.2 4.2 9.5 13.1 25.7 7.2 3.0 20.9 8.4 2.8 21.2 12.5 10.4 6.6 8.5 14.7 13.4 10.7 6.5 17.0 8.9 5.2 14.6 6.2 5.3 22.8 13.0 10.7 11.8 8.0 7.5 8.0 4.6 3.3 1.6 7.5 15.6 5.1 7.8 0.3 6.5 7.7 20.1 10.8 0.0 14.1 8.9 11.7 7.1 1.2 5.4 20.4 3.5 10.7 4.6 17.8 12.7 13.8 17.4 2.0 14.3 56.1 2.6 8.8 27.7 4.8 10.1 3.4 11.5 19.4 10.7 2.9 26.3 13.4 1.0 23.1 1.3 1.4 5.6 18.4 18.2 15.4 9.5 0.6 6.5 6.7 72.9 0.0 8.6 0.1 6.0 6.4 9.3 12.2 15.9 11.3 4.3 3.6 0.8 14.1 20.4 7.1 1.0 1.0 3.3 9.1 1.1 10.9 8.0 9.2 9.8 4.6 6.1 10.8 8.9 0.3 7.5 1.6 1.8 15.6 5.1 17.3 30.3 26.6 36.8 19.3 15.2 13.1 25.7 21.2 5.3 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845605 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 406.4" "Cell line enriched" "Detected in some" 5 "U-87 MG: 20.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.6 0.2 0.2 0.0 3.0 0.8 0.3 5.0 0.6 0.2 0.2 0.0 0.3 0.2 0.2 0.2 1.1 0.2 0.2 0.1 11.6 0.7 0.2 0.2 0.2 0.2 0.2 1.5 0.0 1.2 406.4 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.3 0.5 0.2 1.0 0.3 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.2 4.5 2.2 3.7 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.7 1.4 0.1 0.6 0.3 0.4 0.0 20.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.8 0.3 0.2 0.1 0.2 0.2 0.3 0.2 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol 69000000 "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 44.6 67.9 69.3 38.1 64.9 33.7 45.4 57.2 62.7 34.0 36.4 33.4 43.2 27.3 35.8 56.6 40.9 39.0 41.6 71.7 56.9 57.2 60.5 77.1 28.6 46.1 61.6 57.2 45.9 60.4 66.6 48.4 44.6 41.2 44.7 39.5 38.6 46.5 39.4 128.7 19.8 27.5 48.1 52.5 37.5 37.2 38.2 32.2 38.8 71.6 43.3 46.5 41.3 43.4 49.5 141.8 38.8 61.0 52.8 87.2 90.6 68.2 61.5 61.3 70.4 66.0 63.5 30.1 63.6 59.6 62.6 50.6 56.0 74.8 84.7 71.9 68.2 49.0 66.1 85.0 81.4 75.3 71.4 91.0 91.9 83.1 57.0 86.8 56.1 59.8 36.3 63.8 76.7 65.6 88.3 63.1 86.8 63.9 60.4 110.3 50.0 63.5 46.5 82.3 116.1 98.2 35.1 71.7 60.2 63.6 98.3 99.2 54.8 64.7 62.1 57.8 46.1 53.3 69.7 61.3 98.3 120.5 76.2 132.9 81.8 22.7 61.0 38.8 52.6 55.4 49.7 49.5 52.7 62.2 73.9 38.6 45.6 52.4 21.0 52.8 44.1 141.8 87.2 90.6 69.3 64.9 57.2 62.7 56.9 57.2 61.6 57.2 41.2 32.2 PARP1 "ADPRT, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360691-226408079 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm 39000 Nucleoplasm "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: , CAB075727: , HPA045168: " "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavourable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavourable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 17.3 16.6 31.2 35.7 31.2 14.3 15.3 21.1 29.2 14.3 21.8 37.4 10.3 15.0 18.2 13.0 18.1 15.0 10.8 24.2 27.8 21.9 13.4 24.8 14.1 56.3 40.7 21.8 14.6 28.1 62.6 22.9 28.7 30.4 22.0 19.2 16.3 17.0 24.7 47.3 11.7 19.6 25.5 49.1 32.7 15.9 22.5 34.8 29.5 14.5 16.5 70.2 19.9 13.7 53.0 16.5 9.0 17.5 11.1 21.8 11.5 28.5 15.3 42.6 30.1 11.2 9.2 24.3 18.9 16.9 25.8 21.2 24.3 14.0 83.2 28.3 11.5 21.5 58.5 18.6 22.7 34.9 81.7 32.2 20.4 15.9 6.7 53.4 15.6 9.1 7.4 20.7 14.7 20.0 51.2 42.5 13.3 13.6 17.1 19.3 78.4 30.4 51.8 73.0 76.9 12.1 20.4 42.9 37.6 24.6 27.6 15.5 23.2 33.5 15.2 13.7 22.7 18.5 35.4 17.3 29.0 71.5 11.4 18.1 30.7 9.0 6.7 6.9 18.3 11.3 21.6 46.8 19.4 18.0 14.3 53.0 15.2 16.4 1.0 11.1 17.5 16.5 21.8 11.5 31.2 31.2 21.1 28.4 27.8 21.9 40.7 21.8 30.4 34.8 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 4.9 6.7 9.1 11.5 0.7 1.4 12.1 4.8 1.5 4.4 6.2 5.4 5.0 2.6 1.0 1.1 12.5 10.3 4.1 3.2 10.4 9.7 7.1 12.4 9.6 0.5 9.7 11.2 0.6 3.3 4.6 1.3 3.1 9.2 3.5 3.1 5.6 11.5 10.2 10.1 4.1 18.3 9.2 3.2 1.7 11.2 16.1 4.9 2.8 5.5 2.1 4.6 7.0 4.1 6.1 5.5 7.7 6.4 4.8 4.8 12.2 3.8 7.3 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848233-66958376 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 41.1;liver: 76.0" "Cell line enhanced" "Detected in many" "HeLa: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 3.8;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria 96000 Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavourable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favourable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 41.1 10.7 11.1 2.8 14.6 3.1 12.9 13.1 14.9 2.4 3.8 10.7 21.4 5.6 2.1 2.4 5.0 2.7 2.9 4.0 11.3 8.9 18.7 76.0 2.1 1.6 15.5 11.5 4.4 4.3 19.4 4.0 4.1 10.9 5.4 3.1 3.4 24.2 24.4 5.7 2.8 6.7 1.8 9.4 1.5 3.3 6.1 13.1 0.6 4.2 2.5 2.5 2.2 2.1 0.6 2.6 0.0 3.8 0.3 2.9 2.0 2.9 8.9 3.3 8.1 13.7 5.4 3.5 1.8 7.8 3.5 3.4 4.4 3.2 0.0 3.7 2.9 3.8 3.7 20.6 1.0 1.7 5.2 4.4 27.7 17.0 10.7 0.0 5.7 20.6 5.3 2.8 6.4 2.9 8.4 0.0 1.2 19.0 5.0 2.4 6.3 7.4 3.7 6.9 1.8 3.2 0.9 7.2 10.2 17.3 9.2 7.0 7.5 1.2 3.2 3.9 3.6 4.6 2.0 1.9 2.2 0.0 4.0 2.8 3.3 0.0 3.8 0.0 1.2 0.9 1.4 0.2 0.5 1.9 2.6 0.6 2.9 1.6 0.0 0.3 0.5 1.0 1.5 2.0 11.1 14.6 13.1 13.6 11.3 8.9 15.5 11.5 10.9 13.1 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 156.3;liver: 115.1" "Cell line enhanced" "Detected in many" "HHSteC: 34.9;hTCEpi: 33.9;SK-MEL-30: 32.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria 3300000 Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favourable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 8.2 2.5 1.0 4.9 1.9 1.0 4.3 1.3 1.3 1.3 69.7 1.4 6.9 51.8 1.3 8.5 4.5 1.2 4.2 2.6 1.5 1.0 26.4 115.1 6.0 4.4 1.7 1.2 1.8 8.5 3.4 1.7 1.2 1.8 2.0 5.4 1.9 11.5 4.9 1.0 2.7 156.3 1.1 1.7 6.7 3.3 3.9 1.3 1.3 5.8 1.9 4.6 2.8 1.9 8.8 10.8 2.4 15.1 1.5 6.5 3.9 5.4 3.1 0.9 5.8 3.6 3.7 14.8 6.8 8.2 5.7 9.3 5.1 6.3 13.9 0.8 10.5 8.0 6.0 8.8 4.7 7.1 0.2 2.5 1.7 27.2 34.9 4.8 11.0 4.3 33.9 3.6 8.8 4.6 7.1 25.8 2.2 23.7 1.2 2.4 1.0 4.1 2.8 3.4 7.9 1.7 8.5 3.7 5.9 5.2 6.8 32.1 9.1 7.5 0.8 1.2 6.6 1.8 1.9 17.7 5.5 3.4 3.5 7.7 3.0 0.1 8.2 2.4 3.1 15.1 3.4 8.8 3.5 3.5 10.8 6.1 2.2 2.0 1.0 1.5 14.4 1.9 6.5 3.9 1.0 1.9 1.3 1.3 1.5 1.0 1.7 1.2 1.8 1.3 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754013-83162930 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.3" "Group enriched" "Detected in some" 28 "REH: 61.0;U-2 OS: 70.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 3.1 7.9 8.8 0.8 26.3 0.4 4.7 50.3 19.4 3.2 3.9 1.6 0.4 2.9 1.0 7.3 2.3 2.0 1.9 2.2 9.8 5.7 8.2 0.6 1.8 0.6 4.6 12.6 1.9 4.0 11.4 19.2 1.0 9.1 4.9 3.5 3.6 2.5 5.0 0.6 2.6 2.4 0.7 5.3 1.1 2.9 4.5 4.4 0.0 8.4 0.0 0.8 1.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 1.3 0.5 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.4 0.0 2.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 1.1 61.0 1.0 0.0 0.4 0.2 1.1 0.8 0.0 0.6 0.1 0.7 0.1 0.0 0.0 70.0 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.8 26.3 50.3 19.4 9.8 5.7 4.6 12.6 9.1 4.4 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.0;thyroid gland: 79.5" "Group enriched" "Detected in some" 5 "AF22: 35.8;SCLC-21H: 9.4" "Group enriched" "Detected in many" 6 "pancreatic cancer: 14.6;thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Vesicles "HPA049627: " "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 1.6 35.0 16.3 1.7 20.5 1.3 1.3 7.7 27.8 2.9 4.2 1.6 0.0 6.2 0.9 1.2 2.1 2.0 1.4 3.1 18.0 11.1 1.1 1.0 2.2 0.8 4.1 16.2 11.6 23.7 0.9 1.7 1.5 9.0 1.3 2.8 16.6 2.7 2.3 1.0 16.6 3.3 1.3 5.4 0.9 11.9 4.7 3.8 0.0 79.5 0.0 0.9 1.9 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 20.5 7.7 27.8 18.0 11.1 4.1 16.2 9.0 3.8 PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039548-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 47.1;lung: 14.6" "Cell line enhanced" "Detected in some" "A-431: 28.4;HaCaT: 38.1;HeLa: 33.2;RPTEC TERT1: 18.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 9 "cerebellum: 6.9;pons and medulla: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" 143000000 300000000 "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavourable (2.40e-4)" 0.2 0.1 0.0 6.1 0.5 0.4 0.0 6.9 0.2 0.6 4.4 0.0 0.0 3.9 0.2 0.7 5.2 0.4 2.6 0.0 0.0 0.0 0.1 47.1 14.6 0.0 0.1 0.0 0.1 11.0 0.0 0.0 0.0 2.6 0.0 1.9 0.1 0.3 0.3 0.0 0.8 5.1 0.8 0.1 0.2 1.0 0.4 0.0 0.0 0.0 6.1 0.9 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 6.3 0.9 0.0 2.1 1.4 0.0 0.0 0.0 0.0 0.0 13.2 4.5 0.0 5.2 2.5 38.1 1.1 11.6 0.0 0.0 0.0 0.0 33.2 9.2 0.7 0.0 0.0 2.2 8.6 8.4 6.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.4 0.6 0.0 0.0 0.3 18.8 0.0 0.5 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.2 0.0 0.0 0.1 0.0 2.6 0.0 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643723-14872044 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 42.6" "Cell line enhanced" "Detected in many" "HL-60: 13.3;Karpas-707: 15.4;THP-1: 16.3;U-266/70: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 5.0;T-cells: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA056111: " "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favourable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 42.6 1.0 2.3 12.6 2.2 6.7 17.0 19.2 3.0 2.9 21.8 0.9 0.8 2.2 0.9 1.4 2.6 1.0 6.9 4.7 2.2 2.1 2.4 18.2 10.2 14.1 1.6 1.6 0.9 7.3 0.3 5.1 5.5 1.5 10.7 8.1 1.9 16.5 1.3 0.8 0.9 6.3 9.7 2.1 8.7 3.0 12.5 0.8 7.8 1.2 2.3 7.1 10.5 4.5 0.3 0.4 5.0 1.2 0.1 8.7 1.8 0.0 1.5 3.3 5.4 6.6 0.0 1.3 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.1 11.1 0.1 8.1 10.0 2.3 13.3 0.0 0.5 0.0 0.0 0.3 0.0 11.7 15.4 0.0 0.1 2.6 6.5 4.5 2.4 6.4 1.5 10.0 0.0 1.1 5.1 9.5 1.3 8.6 2.9 0.0 16.3 0.0 0.0 0.8 0.0 0.0 17.4 5.3 0.4 0.1 2.3 1.0 0.0 0.7 2.9 1.4 0.7 2.9 0.3 4.2 3.2 0.4 0.2 8.7 7.5 5.0 0.1 1.2 0.1 4.2 1.8 2.3 2.2 19.2 3.0 2.2 2.1 1.6 1.6 1.5 0.8 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favourable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.4 11.3 10.1 11.9 9.0 1.2 7.1 10.5 10.6 10.3 0.9 7.1 8.2 11.9 19.8 3.1 7.5 2.8 10.5 16.5 10.4 7.3 9.2 6.9 6.4 0.0 8.0 18.9 11.0 6.9 0.5 9.2 2.9 8.2 6.0 8.3 6.1 0.0 2.4 9.1 9.2 25.2 11.1 5.8 5.5 7.5 11.4 10.0 3.2 4.7 18.5 7.3 4.7 12.5 10.3 8.5 5.1 16.2 15.3 4.4 18.3 2.6 8.0 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205337-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 199.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 30.6" "Group enriched" "Detected in all" 6 "B-cells: 7.6;dendritic cells: 22.1;monocytes: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Approved Nucleoplasm,Cytosol 240000 "Nucleoplasm, Cytosol" "HPA028356: AB_10602814, HPA070820: " "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavourable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 45.3 20.4 105.3 28.7 83.6 3.8 25.3 30.5 173.1 25.1 15.5 68.1 5.0 8.0 21.5 21.8 22.6 19.2 22.1 53.9 70.5 81.3 14.8 10.4 23.8 16.6 106.5 67.0 19.7 9.7 14.9 10.2 25.1 74.1 24.4 15.3 18.2 12.3 31.1 10.2 16.9 8.8 47.4 199.4 23.8 10.0 17.5 53.7 1.6 12.6 6.0 22.9 22.4 17.5 7.6 22.1 1.8 30.6 3.1 3.5 5.4 16.7 5.8 24.3 10.5 45.1 25.3 8.1 72.8 63.6 60.6 42.6 12.8 9.1 7.8 26.4 90.8 18.3 9.0 22.8 47.4 4.2 5.0 6.4 4.1 3.2 55.7 2.1 7.9 21.2 12.9 33.3 42.5 45.5 6.6 14.3 81.0 8.3 2.5 5.0 16.1 16.8 4.2 25.6 5.3 22.0 8.8 4.8 12.9 38.6 26.4 22.2 16.2 15.1 60.6 40.3 31.6 30.0 31.2 11.3 6.9 14.8 37.1 4.1 57.0 0.3 15.3 1.8 3.5 30.6 2.7 7.6 2.6 2.8 22.1 5.0 1.6 1.8 0.7 3.1 13.9 9.7 2.9 5.4 105.3 83.6 30.5 78.2 70.5 81.3 106.5 67.0 74.1 53.7 PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244038-238290102 "Disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060510 Enhanced "HPA060510: " "unprognostic (1.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.88e-2)" "unprognostic (9.28e-2)" "unprognostic (2.52e-1)" "prognostic favourable (2.29e-4)" "unprognostic (2.47e-2)" "unprognostic (2.17e-2)" "unprognostic (3.59e-3)" "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" 12.7 3.8 5.1 11.4 10.3 7.8 16.1 16.0 13.4 16.4 8.8 9.2 12.8 5.5 15.4 9.7 15.2 11.8 15.6 6.7 5.8 4.7 4.9 13.7 7.9 4.8 4.7 6.8 14.6 15.7 5.5 11.1 8.4 8.0 12.9 7.1 11.6 23.0 20.7 11.9 20.0 9.1 13.5 4.5 4.9 14.8 19.0 5.3 6.0 9.9 21.3 13.7 11.1 11.3 4.5 4.8 4.1 5.6 3.1 4.5 0.8 1.3 10.0 2.1 3.6 0.1 1.1 7.2 0.9 3.6 1.3 1.3 1.5 5.0 8.7 1.0 2.3 7.4 2.0 3.0 1.9 2.4 1.5 7.7 5.1 6.8 1.8 11.4 8.1 1.4 7.3 1.6 5.3 0.7 3.7 5.5 1.1 6.4 5.7 12.7 3.1 2.0 13.8 4.9 2.8 1.3 2.8 8.5 1.0 2.5 5.5 1.6 5.1 7.2 1.8 3.2 3.8 2.5 3.4 6.2 1.4 10.6 5.9 5.0 3.9 4.1 3.7 0.9 2.9 5.6 4.5 4.4 4.5 3.4 3.7 4.5 4.4 4.5 2.9 3.1 5.1 4.8 3.1 0.8 5.1 10.3 16.0 13.4 5.8 4.7 4.7 6.8 8.0 5.3 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 24.2;liver: 24.4;skeletal muscle: 48.3" "Group enriched" "Detected in some" 4 "ASC diff: 13.6;Hep G2: 5.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 24.2 0.2 0.1 1.6 0.1 0.1 13.1 0.1 0.2 0.1 1.7 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.4 24.4 0.1 1.6 0.1 0.1 0.1 0.6 0.2 0.2 0.1 0.1 0.3 0.2 0.1 1.3 0.1 48.3 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 8.3 0.6 0.2 2.0 1.5 0.1 0.0 0.7 1.3 2.1 0.3 0.3 0.2 0.4 0.6 13.6 0.3 1.0 0.0 0.1 0.2 0.0 0.8 0.2 0.6 0.2 0.1 0.5 0.1 0.3 0.4 0.4 1.1 0.4 0.1 5.4 0.0 0.1 0.5 0.2 0.6 0.1 0.4 0.0 0.1 2.1 0.2 0.7 0.6 0.3 0.3 0.3 0.5 0.2 0.1 0.0 0.4 0.4 0.2 0.5 1.5 0.2 0.4 0.0 0.1 0.1 0.5 0.4 0.2 1.1 1.7 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.2 0.7 2.1 1.5 0.2 0.0 0.0 0.8 0.0 0.8 0.0 1.3 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 13.9;plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 8 "dendritic cells: 16.7;granulocytes: 13.9" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA049975: , HPA063575: " "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favourable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.63e-4)" "unprognostic (1.86e-2)" 3.3 6.1 9.8 5.8 16.6 15.7 5.1 2.1 14.6 7.3 16.0 19.5 5.3 23.2 4.0 9.1 7.7 4.5 9.1 22.8 14.1 7.7 22.0 3.6 10.9 5.3 13.4 15.1 4.3 11.9 6.2 27.5 3.0 25.3 3.9 18.1 22.4 6.3 3.5 34.9 6.4 18.7 4.0 17.4 12.5 10.7 6.1 15.1 6.5 38.4 8.8 5.0 3.4 3.6 1.6 16.7 13.9 1.9 1.1 0.4 0.4 9.5 4.2 2.8 4.8 5.7 2.8 4.6 1.3 1.7 2.4 1.3 10.2 13.8 1.7 2.2 2.1 13.6 2.0 5.1 1.4 0.3 2.1 13.5 10.6 3.8 4.8 0.0 9.5 4.1 7.8 2.3 12.9 0.5 9.2 0.1 1.3 2.9 2.3 0.4 3.8 6.4 0.0 0.0 0.2 3.3 9.9 4.4 2.7 8.9 15.1 11.2 10.3 1.1 0.2 0.0 5.2 7.3 1.2 4.4 4.4 0.9 5.9 0.0 2.6 1.0 0.9 13.9 0.2 1.9 0.3 1.3 0.1 0.3 0.8 1.6 0.3 0.4 2.6 1.1 1.3 16.7 0.0 0.4 9.8 16.6 2.1 14.6 14.1 7.7 13.4 15.1 25.3 15.1 PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved 1800000 "HPA030047: AB_10602815" "unprognostic (6.21e-3)" "unprognostic (2.93e-1)" "unprognostic (4.46e-2)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (4.41e-4)" "unprognostic (5.69e-2)" "unprognostic (5.40e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-1)" "unprognostic (2.49e-1)" "unprognostic (8.06e-2)" "unprognostic (3.01e-2)" 32.0 16.7 28.0 26.0 29.5 26.4 23.1 21.3 46.0 28.3 38.7 40.9 30.1 65.5 21.3 33.5 33.5 22.8 37.5 18.4 28.8 23.4 40.3 31.3 21.0 25.2 32.4 33.0 19.5 27.1 12.3 17.1 31.9 29.1 20.2 17.2 36.3 28.8 28.5 8.3 31.1 59.3 20.5 36.1 28.1 42.7 24.0 29.1 16.4 20.4 15.4 26.0 27.2 23.9 20.3 26.9 5.2 38.0 7.7 25.2 22.8 32.3 14.2 10.1 29.2 15.9 11.9 44.5 24.4 15.8 14.2 14.0 19.0 7.1 19.2 29.0 16.2 17.7 8.0 22.1 3.2 16.1 18.2 38.8 12.4 31.0 12.3 29.2 24.7 15.5 13.5 14.4 7.1 20.8 23.9 22.0 9.6 41.1 12.6 22.8 15.9 15.9 31.2 9.6 52.1 6.4 35.8 17.8 13.4 35.5 30.1 15.6 23.9 25.9 30.1 21.5 13.9 14.0 9.4 42.8 11.5 7.9 35.8 23.3 17.2 5.1 22.2 5.2 12.9 37.9 10.8 14.4 17.0 11.8 26.9 20.3 10.2 7.9 4.5 7.7 38.0 17.0 25.2 22.8 28.0 29.5 21.3 46.0 28.8 23.4 32.4 33.0 29.1 29.1 PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 284.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002117 Approved Approved "Endoplasmic reticulum" 1100000 "Endoplasmic reticulum" "HPA002117: AB_1855245" "unprognostic (4.60e-2)" "unprognostic (2.56e-3)" "unprognostic (2.56e-3)" "prognostic unfavourable (5.85e-6)" "unprognostic (4.97e-1)" "prognostic unfavourable (7.91e-5)" "unprognostic (5.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.29e-3)" "unprognostic (6.73e-2)" "prognostic favourable (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.72e-2)" "unprognostic (1.30e-2)" 4.4 11.6 10.0 3.0 16.2 2.3 3.9 13.0 23.6 5.8 5.3 6.1 5.4 3.0 6.4 5.8 9.1 5.4 4.8 55.5 8.2 10.1 10.9 2.7 3.6 2.4 9.4 10.8 10.8 3.0 14.2 11.4 3.3 17.9 7.1 4.2 10.8 5.2 9.4 284.3 2.6 2.8 8.3 4.6 2.7 4.1 10.3 3.8 0.0 5.5 54.9 4.6 5.3 3.7 10.7 6.7 8.7 3.2 2.2 5.4 3.5 8.7 8.5 27.0 24.6 27.6 20.1 5.5 23.7 21.8 20.5 14.6 21.0 11.0 52.2 19.7 11.5 9.8 23.4 23.9 19.3 1.2 12.2 14.9 19.4 0.7 14.8 0.7 8.6 28.4 14.1 18.0 29.7 23.3 17.8 26.4 18.9 6.6 18.3 1.2 19.3 26.5 30.9 15.8 40.1 14.0 9.7 32.0 23.5 14.0 22.3 23.7 22.5 3.2 20.9 9.5 13.2 13.9 19.7 14.4 38.4 28.6 18.4 1.5 8.0 0.4 3.2 8.7 2.5 2.8 1.0 10.7 4.3 2.4 6.7 7.0 5.4 3.0 0.8 2.2 2.3 1.0 3.8 3.5 10.0 16.2 13.0 23.6 8.2 10.1 9.4 10.8 17.9 3.8 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" "HPA020200: " "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favourable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 8.9 3.4 13.8 4.6 2.3 2.0 10.8 2.7 2.4 5.4 5.5 7.3 5.4 6.0 1.6 4.0 11.0 7.1 4.2 6.9 18.6 5.9 2.0 3.7 13.4 3.3 3.0 1.0 2.1 2.8 5.7 5.3 3.8 5.1 12.2 5.1 2.0 2.2 2.6 5.6 3.3 21.4 7.8 7.2 3.0 11.6 6.4 2.6 2.9 6.7 5.5 2.9 8.8 4.8 4.4 2.1 2.6 6.2 1.4 0.7 7.1 2.6 3.5 3.3 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nuclear bodies,Cytosol" 430000 Cytosol "Nuclear bodies" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 15.8 26.4 31.5 12.1 28.0 11.7 15.3 14.7 27.2 19.2 15.7 18.5 13.7 14.7 11.2 21.7 13.7 21.1 14.2 59.1 22.7 19.3 18.4 12.6 12.1 12.7 27.0 21.0 13.7 46.5 15.6 21.2 14.7 20.8 20.2 11.6 14.1 30.5 22.6 86.0 9.2 16.3 16.9 24.3 10.3 13.4 13.8 18.6 7.5 20.7 19.8 10.4 12.0 9.8 24.9 48.8 3.3 35.4 20.0 24.3 32.1 7.1 52.2 29.8 19.0 19.3 35.0 43.8 16.7 21.3 20.4 18.1 19.0 16.3 15.2 20.3 20.6 19.0 6.5 37.7 6.4 13.6 13.2 4.8 34.3 41.7 24.0 9.5 19.6 43.6 31.0 11.7 14.1 26.7 11.5 14.2 31.6 40.7 13.9 20.1 23.6 22.5 11.5 13.0 25.1 32.2 11.9 14.6 13.9 17.9 21.1 8.7 16.0 26.5 21.7 42.6 13.2 11.8 15.4 9.4 9.1 9.3 24.1 6.9 25.5 2.9 35.4 3.3 24.3 34.2 20.9 24.9 21.1 21.9 37.5 16.5 15.0 21.3 1.7 20.0 24.0 48.8 22.9 32.1 31.5 28.0 14.7 27.2 22.7 19.3 27.0 21.0 20.8 18.6 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652699-138834938 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 41.2;HMC-1: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: " "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavourable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 12.5 9.9 10.6 9.7 20.6 17.4 11.5 29.9 25.0 12.4 14.6 11.9 11.7 13.7 9.6 6.9 15.2 10.9 8.7 12.7 12.2 14.2 22.6 9.3 9.5 9.1 11.9 15.2 8.8 20.3 20.2 10.9 18.1 24.1 13.4 15.7 12.2 14.9 15.9 33.4 19.6 16.4 8.3 12.5 9.9 11.0 6.4 10.7 14.4 37.4 7.1 11.9 13.4 11.0 4.6 9.1 11.3 7.8 1.3 6.5 2.6 22.6 9.8 4.2 3.5 3.9 5.2 28.7 5.3 5.1 5.4 5.8 10.5 8.6 9.1 14.5 5.2 9.7 5.5 8.4 9.7 11.6 6.2 41.2 6.7 6.3 4.0 10.0 65.3 4.4 6.5 3.8 7.7 8.1 15.7 6.8 6.7 10.3 5.8 7.0 6.0 9.2 4.2 4.4 6.5 8.3 12.5 3.7 2.7 14.7 6.4 18.9 16.0 23.9 8.5 3.5 4.4 7.5 7.4 11.5 7.5 8.3 8.5 9.7 4.8 7.0 7.8 11.3 4.0 4.5 2.7 4.6 5.2 3.0 9.1 4.1 6.5 4.4 10.0 1.3 4.3 1.4 2.2 2.6 10.6 20.6 29.9 25.0 12.2 14.2 11.9 15.2 24.1 10.7 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol Cytosol "HPA068758: " "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favourable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.2 4.8 3.2 6.1 2.5 1.9 18.5 4.6 7.4 5.4 3.9 8.0 6.2 12.9 5.8 1.2 6.2 6.2 3.4 1.9 9.7 25.7 5.3 11.5 9.6 12.0 11.5 10.3 3.6 11.5 3.3 5.7 17.6 7.3 45.7 1.6 16.2 5.8 20.6 6.8 7.7 27.2 5.4 15.3 2.9 5.5 11.6 8.1 8.9 40.6 28.4 5.3 15.3 4.6 3.4 14.8 5.6 7.4 23.5 14.9 11.0 8.6 6.5 9.2 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301434 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.2;kidney: 12.4;liver: 47.8" "Cell line enriched" "Detected in some" 9 "K-562: 47.4" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Low region specificity" "Detected in some" "HPA006653, CAB034376, CAB034378" Enhanced Approved "Golgi apparatus,Cytosol" 2900000 "Golgi apparatus, Cytosol" "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: " "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.1 0.0 0.1 0.3 0.1 7.2 0.1 0.9 0.2 0.1 4.9 0.1 0.1 5.8 0.1 1.3 0.1 0.0 0.7 0.1 0.1 0.4 12.4 47.8 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.6 17.2 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.4 0.1 0.1 0.1 0.1 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.2 22.2 8.3 17.2 13.4 15.8 13.7 13.4 16.1 14.2 13.6 8.6 21.4 35.6 34.8 23.0 8.6 13.2 6.0 5.5 28.8 17.1 42.6 14.2 18.4 44.5 16.7 26.8 11.4 4.3 8.6 13.5 32.9 18.8 24.7 10.4 15.3 25.2 15.5 15.0 25.4 33.9 11.3 25.6 7.0 6.1 30.2 42.8 8.3 10.6 21.7 9.6 29.2 49.2 28.3 12.1 34.1 20.3 32.5 29.6 19.4 18.5 33.6 22.1 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322111-120327789 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 933 "pancreas: 2360.6" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;Hep G2: 6.3;U-2 OS: 4.6" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Group enriched" "Detected in many" 19 "NK-cells: 1.3;T-cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" 3900000 "HPA047822: , HPA060803: " "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 1.1 0.1 0.1 0.1 1.1 2360.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.3 2.5 0.9 0.2 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.5 0.0 0.3 1.3 0.3 1.6 0.0 0.0 0.2 0.0 0.6 0.0 1.0 0.2 4.6 0.6 0.6 0.0 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.3 0.0 0.0 2.5 0.9 0.0 1.3 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38205690 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" "Calmodulin-binding, Hydrolase" "Disease mutation, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4;HMC-1: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001171 Approved Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favourable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favourable (1.55e-4)" 16.2 17.7 15.6 8.5 20.5 13.1 15.6 15.9 26.3 14.8 7.9 36.9 18.5 9.8 16.3 20.5 8.7 21.6 25.3 6.3 19.7 7.2 18.1 8.6 9.0 12.4 19.3 16.7 21.3 12.8 24.2 12.7 6.8 19.5 17.6 6.3 12.9 20.2 17.4 7.4 18.1 8.7 7.8 14.9 12.1 9.5 30.0 23.2 16.3 45.7 4.1 11.3 12.1 11.2 1.8 5.4 4.1 0.9 8.8 5.7 1.9 0.7 2.8 3.0 7.7 10.0 4.9 8.1 0.9 0.9 0.8 1.1 3.1 1.8 5.8 6.6 2.3 3.6 3.4 1.9 1.0 8.9 13.1 31.4 3.8 3.5 2.8 3.5 20.1 16.1 4.3 2.8 4.4 1.0 5.1 10.6 1.5 4.6 6.5 2.1 2.5 1.8 4.8 1.1 4.5 2.9 6.9 5.7 2.4 1.3 3.1 7.1 3.2 2.5 1.2 2.6 4.4 1.1 0.5 17.4 3.1 3.1 3.7 4.0 1.5 4.1 0.9 0.4 3.8 0.3 1.9 1.8 3.1 5.7 1.5 1.5 1.4 3.9 3.3 8.8 0.6 5.4 3.7 1.9 15.6 20.5 15.9 26.3 19.7 7.2 19.3 16.7 19.5 23.2 PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548298-118560730 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 337.5" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.4;Karpas-707: 1.6;NB-4: 1.9;U-2197: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "eosinophil: 1.3;naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005597, HPA026900" Enhanced "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavourable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavourable (5.59e-4)" 9.0 1.8 0.4 2.7 0.5 0.0 5.4 0.4 0.6 22.3 22.2 0.0 9.8 2.0 21.1 22.3 27.3 11.6 29.8 337.5 0.4 0.5 6.4 0.4 5.3 0.8 0.7 1.4 18.6 0.5 0.1 0.4 0.1 1.4 14.4 3.9 0.0 1.6 6.0 68.4 1.5 14.0 30.8 1.2 0.6 6.5 12.3 0.0 0.0 2.8 23.7 0.8 32.2 6.6 0.3 0.0 1.3 0.4 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.0 0.3 0.5 0.2 0.0 0.2 1.6 0.1 0.0 0.0 1.9 0.1 0.0 0.0 0.1 1.0 0.0 0.7 0.2 0.8 0.4 0.1 0.0 0.4 0.0 0.5 0.3 0.2 1.3 0.3 0.2 0.3 0.5 0.0 1.1 0.1 0.0 0.4 1.3 0.1 0.0 0.3 0.1 0.4 0.0 0.0 0.3 1.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.6 0.4 0.5 0.7 1.4 1.4 0.0 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 12.1;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;granulocytes: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm Nucleoplasm "CAB075701: , HPA058901: , HPA067049: " "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favourable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 5.7 6.6 5.8 6.0 6.2 4.2 6.9 2.6 4.5 3.8 11.8 5.9 9.9 13.9 4.8 6.6 6.3 3.9 9.1 19.6 5.1 4.1 17.8 30.9 3.8 3.4 6.1 4.9 9.1 13.4 6.6 3.5 3.1 7.8 6.2 7.1 13.5 8.1 8.2 17.1 5.8 19.7 5.0 4.7 3.5 5.7 2.7 7.1 1.3 5.4 10.4 4.8 7.3 12.3 1.5 3.8 12.1 1.4 0.9 1.5 0.3 6.8 1.7 2.1 7.6 12.1 7.8 4.8 5.9 11.9 6.4 6.6 3.3 3.3 2.4 3.0 13.8 3.1 6.4 7.8 5.8 7.0 8.1 7.6 4.3 7.0 7.6 5.1 13.0 6.1 6.3 4.7 10.9 1.3 2.7 5.7 5.9 1.7 5.8 1.9 0.3 1.7 6.9 7.8 3.2 4.4 4.0 2.1 6.4 2.3 2.1 7.5 2.4 4.0 2.3 6.7 7.2 6.0 2.6 5.7 3.3 1.0 10.5 5.8 2.0 1.7 1.0 12.1 1.4 1.4 1.2 1.0 0.7 0.7 0.7 1.5 0.8 0.6 0.8 0.9 0.8 3.8 1.5 0.3 5.8 6.2 2.6 4.5 5.1 4.1 6.1 4.9 7.8 7.1 PPARD "FAAR, NR1C2, NUC1, NUCII" ENSG00000112033 "Peroxisome proliferator activated receptor delta" Q03181 6 35342558-35428191 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017635 Approved "CAB017635: AB_1128605" "unprognostic (3.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (8.68e-2)" "prognostic unfavourable (4.57e-4)" "unprognostic (4.59e-3)" "unprognostic (4.34e-1)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-3)" "unprognostic (7.27e-3)" "unprognostic (1.43e-1)" "unprognostic (9.42e-2)" "unprognostic (5.95e-2)" "unprognostic (2.00e-2)" 16.4 13.4 20.4 19.4 21.8 8.8 11.3 19.0 29.5 14.0 19.0 20.4 24.5 12.7 15.0 22.7 29.6 13.4 16.7 15.7 23.8 14.5 11.9 19.9 18.1 15.6 22.5 14.6 21.6 11.1 14.2 16.2 30.4 19.8 18.0 13.9 15.4 15.2 20.6 22.5 26.3 16.5 12.8 20.9 20.0 23.4 12.8 20.8 6.2 26.8 9.5 15.8 14.5 19.4 4.4 2.9 6.7 3.5 2.3 5.6 2.5 20.7 3.7 5.9 12.5 8.7 15.4 31.9 17.0 15.3 14.7 12.3 5.0 3.9 3.4 5.0 12.1 7.5 5.5 16.5 10.3 4.8 5.0 3.1 4.9 7.3 15.3 0.7 3.6 26.1 5.5 21.7 11.2 6.8 3.3 3.8 12.3 6.5 2.2 3.3 2.8 10.1 3.2 10.1 3.3 3.6 18.6 3.3 9.2 6.8 11.9 14.5 4.4 11.6 14.7 20.1 7.6 12.0 20.2 3.2 4.4 3.7 6.5 6.7 8.9 1.1 3.5 6.7 3.1 3.3 2.2 3.4 3.3 3.0 2.9 4.4 5.6 5.1 5.4 2.3 1.9 1.8 3.2 2.5 20.4 21.8 19.0 29.5 23.8 14.5 22.5 14.6 19.8 20.8 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease mutation, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 97.6;breast: 102.1" "Cell line enhanced" "Detected in many" "ASC diff: 47.4;ASC TERT1: 27.0;BEWO: 55.9;CAPAN-2: 25.0;HSkMC: 27.8;PC-3: 24.9;RT4: 34.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: , HPA063663: " "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavourable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favourable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favourable (5.52e-5)" 97.6 1.6 1.9 17.1 1.2 0.7 102.1 1.5 1.3 3.1 24.9 0.8 2.1 7.5 3.5 2.2 2.8 2.4 8.7 12.5 1.4 0.9 6.7 5.9 24.8 11.4 1.1 0.9 6.7 1.2 2.8 0.3 26.8 0.9 10.4 13.9 1.1 5.8 1.5 5.0 2.7 9.6 7.4 1.2 7.0 11.9 3.5 0.6 0.9 6.2 4.3 2.1 30.2 14.1 0.0 0.4 0.0 2.3 0.0 0.7 0.3 9.6 8.6 0.0 0.0 47.4 27.0 55.9 0.9 10.4 1.3 0.5 1.8 25.0 0.0 0.0 0.9 3.9 3.4 0.1 0.2 23.2 4.8 0.0 1.9 2.3 12.6 0.0 0.0 27.8 2.3 2.3 9.0 0.1 0.0 0.0 2.0 2.4 0.0 0.1 0.1 24.9 0.0 0.0 0.0 7.1 34.1 0.0 0.2 4.0 1.5 0.5 0.0 7.7 7.8 1.8 2.6 1.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.0 1.8 0.0 0.0 2.3 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 1.9 1.2 1.5 1.3 1.4 0.9 1.1 0.9 0.9 0.6 PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036091, HPA036092" Approved Approved "Midbody ring" "Midbody ring" "HPA036091: , HPA036092: AB_10603132" "unprognostic (5.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.15e-5)" "unprognostic (1.38e-1)" "unprognostic (4.37e-3)" "prognostic unfavourable (1.14e-8)" "unprognostic (6.74e-3)" "unprognostic (2.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.88e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (8.34e-4)" "unprognostic (1.41e-1)" "unprognostic (3.01e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.09e-1)" 5.6 10.1 10.8 9.5 11.7 7.3 11.1 11.7 13.7 7.3 6.0 6.9 7.6 6.1 7.4 5.6 8.1 7.1 5.3 4.4 8.9 9.7 9.7 10.3 3.9 12.0 9.7 12.1 12.5 10.8 5.6 6.8 10.3 9.5 6.2 7.7 3.8 9.2 7.6 7.0 6.7 5.1 5.6 9.7 6.3 5.5 13.0 8.9 15.2 9.4 6.4 12.0 7.0 6.6 8.2 3.7 3.3 3.9 11.2 9.5 4.3 8.6 7.2 14.9 7.2 4.8 6.3 12.1 9.6 4.3 8.0 8.5 14.4 10.6 30.4 13.2 4.5 6.4 28.6 9.7 16.1 7.9 12.7 12.2 9.1 15.9 7.4 24.1 7.7 5.4 7.6 11.4 12.8 8.4 30.8 16.8 9.0 7.8 29.7 18.3 19.7 8.6 25.2 9.7 21.3 13.4 6.1 25.2 12.3 7.7 14.1 8.7 9.5 5.2 5.8 8.4 14.5 8.4 17.0 12.6 12.6 31.6 9.3 15.4 7.7 3.3 2.0 1.0 4.6 3.1 6.9 8.2 6.3 6.2 2.8 6.3 9.5 8.6 0.5 11.2 3.9 3.7 4.7 4.3 10.8 11.7 11.7 13.7 8.9 9.7 9.7 12.1 9.5 8.9 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell line specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavourable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.4 21.6 16.4 7.4 21.4 19.7 8.7 9.2 7.9 24.3 9.2 9.0 19.3 9.7 13.9 28.5 14.8 22.6 6.4 14.7 19.7 10.2 15.8 23.5 7.5 16.9 15.0 18.9 21.7 16.3 5.7 25.5 13.9 23.3 4.9 17.7 6.4 8.9 9.0 34.9 10.7 8.4 15.4 30.3 11.5 17.7 15.2 10.2 13.6 13.4 18.9 20.6 23.4 18.8 14.1 11.9 12.2 16.4 11.4 13.3 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB005050: AB_562037, HPA035409: , HPA064946: " "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.3 11.8 9.5 12.6 23.5 24.5 9.0 19.3 19.8 14.5 13.0 11.1 14.7 6.7 9.0 19.8 9.2 8.7 17.6 27.5 19.6 7.9 13.3 27.3 8.8 19.4 12.6 14.0 22.6 8.6 19.4 20.0 21.4 6.2 19.4 21.6 5.4 11.6 9.9 4.1 14.3 9.8 20.3 9.8 22.3 19.3 8.2 8.3 33.9 22.6 11.5 11.9 10.5 22.9 26.2 14.2 15.1 15.7 7.7 6.0 8.0 16.4 27.4 13.9 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;RPTEC TERT1: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" "Nuclear speckles" "Golgi apparatus" "HPA044540: " "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavourable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavourable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favourable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.5 4.3 3.8 4.7 0.0 0.6 0.6 0.0 7.8 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 0.8 0.0 0.0 1.0 0.1 0.0 0.0 5.5 5.4 0.0 0.0 0.0 14.0 1.2 2.0 5.4 5.7 0.1 0.0 3.2 0.0 0.0 1.5 2.3 2.7 6.3 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.3 2.5 2.6 6.2 15.9 0.3 13.3 8.7 9.6 8.2 1.4 1.5 3.1 3.6 21.4 0.3 1.3 1.5 20.9 5.1 3.0 0.0 7.3 6.4 8.5 3.8 20.9 6.9 0.6 12.0 10.3 8.2 8.0 0.0 14.8 0.7 7.7 2.3 1.0 6.6 1.4 18.8 0.0 3.4 2.0 1.5 8.5 4.4 2.5 0.1 0.3 5.4 24.5 16.7 9.7 10.4 8.3 0.0 0.0 0.3 53.0 0.0 8.2 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell line enhanced" "Detected in some" "HEL: 40.8;HMC-1: 40.9;K-562: 58.1;THP-1: 18.4;U-937: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: , HPA054203: " "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 40.8 1.9 0.0 0.0 5.9 40.9 0.0 0.1 0.0 0.0 0.0 58.1 0.1 0.0 0.0 12.9 12.9 0.3 0.0 12.3 0.1 2.3 0.1 3.6 7.1 0.0 0.0 0.0 0.6 0.0 18.4 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 16.4 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: " "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favourable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 35.9 9.1 9.2 9.8 8.2 11.4 14.9 9.2 13.7 12.3 13.3 13.3 17.6 11.0 30.5 13.0 16.9 17.3 18.1 21.1 8.0 10.7 10.2 11.6 7.4 13.0 9.2 4.6 10.2 12.7 10.4 16.5 9.5 11.2 9.1 12.3 12.4 13.3 3.6 19.3 10.2 9.6 14.2 18.2 19.3 11.0 14.6 11.9 20.0 26.3 9.0 28.9 6.3 10.1 12.8 9.9 11.9 15.2 15.7 15.1 15.7 9.2 7.2 5.0 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell line enhanced" "Detected in some" "HEL: 30.9;MOLT-4: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" 200000 "Centriolar satellite" "HPA065279: , HPA073098: " "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 1.8 3.3 0.0 0.0 2.1 30.9 0.0 0.2 0.4 1.5 0.3 0.1 2.0 0.1 0.1 0.3 6.7 0.0 0.0 0.0 23.2 4.3 3.2 0.0 4.5 0.7 0.0 6.5 1.6 0.2 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: " "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.4 27.8 27.1 25.7 16.9 17.9 11.5 13.8 13.6 19.5 19.2 18.1 10.7 31.0 12.0 16.9 18.5 35.8 18.9 30.6 6.8 22.2 60.9 25.0 22.2 7.3 23.1 12.7 12.9 6.2 30.7 32.2 20.0 40.5 13.1 21.4 15.2 32.6 19.1 29.8 8.4 16.0 21.3 10.9 9.8 28.0 13.6 17.3 42.6 13.9 13.4 19.9 16.0 23.2 25.5 21.7 20.1 27.7 11.5 14.6 44.6 14.4 26.3 20.6 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347420-162727771 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.8" "Cell line enhanced" "Detected in some" "AN3-CA: 3.6;HEL: 9.0;Karpas-707: 5.7;RPMI-8226: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: " "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favourable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 6.8 7.1 7.9 2.3 12.2 1.5 4.2 7.2 13.4 5.3 4.3 6.3 4.6 2.8 7.8 4.4 6.1 3.4 4.3 17.7 9.2 6.2 17.4 3.6 2.6 3.0 5.8 5.2 6.4 3.0 5.6 8.6 2.0 5.5 4.0 2.4 8.3 3.5 4.8 41.8 4.0 3.3 6.6 5.9 2.7 3.5 10.3 6.8 0.6 3.8 4.7 2.7 4.9 2.1 4.6 1.2 4.2 0.8 1.8 4.6 1.3 0.0 0.3 1.2 3.6 0.9 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 9.0 0.2 0.0 0.8 0.2 0.1 3.1 0.1 0.0 0.5 0.0 0.4 5.7 0.9 0.5 0.1 0.1 0.2 0.8 0.0 0.0 5.7 0.6 0.1 0.9 2.5 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.3 0.1 0.3 0.8 0.1 0.0 0.1 0.1 2.2 2.8 0.8 4.2 2.1 0.5 3.5 1.5 2.0 2.2 1.2 4.6 4.4 4.6 1.5 1.8 0.4 0.3 0.2 1.3 7.9 12.2 7.2 11.7 9.2 6.2 5.8 5.2 5.5 6.8 PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;heart muscle: 4.5" "Cell line enhanced" "Detected in some" "A549: 5.9;MCF7: 4.3;RPMI-8226: 3.6;SK-BR-3: 1.8;T-47d: 2.0;U-87 MG: 2.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 58 "hypothalamus: 13.4;pons and medulla: 22.5" "Region enriched" "Detected in single" 13 "pons and medulla: 5.1" HPA014976 Approved "Secreted - unknown location" "HPA014976: " "unprognostic (8.28e-4)" "unprognostic (3.22e-2)" "unprognostic (5.42e-2)" 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 4.5 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.8 0.3 2.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase, receptor type A" P18433 20 2864184-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles 21000 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: " "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favourable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 21.9 18.5 55.6 14.3 48.6 16.4 23.3 44.5 56.0 29.7 19.7 37.5 9.4 14.7 26.3 18.7 22.7 26.5 21.3 14.0 45.9 41.1 22.1 13.5 21.6 16.9 38.0 46.7 28.6 14.9 41.5 23.4 29.0 52.5 23.5 20.0 18.5 16.7 21.8 8.2 21.0 15.3 25.7 52.6 17.9 16.3 27.4 30.4 20.6 32.4 8.5 20.4 22.9 19.2 7.7 5.7 7.9 6.7 6.2 11.0 3.7 20.5 12.6 36.3 11.1 40.2 73.4 7.7 15.5 30.3 19.2 23.5 15.0 28.6 13.5 12.2 20.7 22.1 14.6 22.1 21.7 20.8 9.4 19.2 5.3 19.0 14.4 19.2 9.1 32.8 22.9 15.8 16.7 26.5 19.2 17.3 19.0 8.4 22.2 21.8 14.0 10.1 17.0 17.6 16.8 16.4 16.0 20.1 19.3 15.0 25.5 23.0 15.9 16.5 18.9 17.1 8.5 19.1 13.6 12.7 17.6 17.8 7.9 18.2 16.0 7.9 4.8 7.5 11.0 4.8 9.0 7.7 7.4 7.9 3.7 5.1 7.4 9.0 6.0 6.2 6.7 5.7 8.1 3.7 55.6 48.6 44.5 56.0 45.9 41.1 38.0 46.7 52.5 30.4 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase, receptor type E" P23469 10 127907061-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 91.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.9;NB-4: 15.0;TIME: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 91.0;plasmacytoid DC: 65.7" "Group enriched" "Detected in all" 11 "dendritic cells: 65.7;granulocytes: 91.0;monocytes: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 16.8 18.5 12.5 24.0 12.5 39.5 11.0 7.4 15.3 4.8 9.2 14.5 1.6 9.6 5.1 8.1 8.8 6.2 10.7 12.3 15.0 12.2 4.4 4.8 22.5 20.0 12.5 6.5 4.3 3.1 3.4 6.5 8.0 9.8 4.5 9.8 4.8 7.0 3.1 1.9 4.9 12.7 7.7 14.3 26.4 7.7 4.3 10.9 11.4 6.6 6.1 12.2 10.0 5.0 1.2 65.7 91.0 25.5 4.0 5.4 4.9 2.0 0.4 0.2 0.0 1.2 0.2 3.6 0.0 0.0 0.8 1.7 0.8 12.0 1.5 1.3 1.0 1.1 1.0 5.8 0.3 1.8 0.9 0.1 0.7 0.0 2.0 7.4 5.6 0.4 3.3 2.9 5.9 19.9 0.0 0.9 1.2 1.8 2.2 15.0 0.1 0.7 8.8 1.2 2.9 3.3 8.6 0.0 1.2 3.4 0.6 0.1 0.3 9.4 37.5 0.8 0.8 3.7 4.1 0.4 0.6 2.1 5.5 5.8 0.0 17.4 25.5 19.3 5.4 9.0 3.2 0.9 2.4 3.6 13.3 1.2 1.7 2.9 91.0 4.0 6.8 65.7 3.5 4.9 12.5 12.5 7.4 12.7 15.0 12.2 12.5 6.5 9.8 10.9 RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Predicted intracellular proteins" "Protein transport, Transport" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054396 Approved "Vesicles,Centriolar satellite" "Vesicles, Centriolar satellite" "HPA054396: " "unprognostic (5.81e-3)" "prognostic favourable (2.08e-4)" "unprognostic (1.13e-2)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (4.78e-2)" "prognostic favourable (7.58e-5)" "unprognostic (1.23e-1)" "prognostic favourable (2.06e-4)" "unprognostic (3.66e-1)" "unprognostic (3.87e-1)" "unprognostic (8.85e-2)" "unprognostic (3.29e-3)" 41.1 38.7 38.1 34.3 51.9 36.5 32.5 43.7 89.0 27.9 29.3 70.8 27.6 46.1 31.0 26.8 38.8 31.0 31.7 56.7 39.6 37.5 40.6 35.9 32.3 32.3 43.6 34.4 35.1 60.5 27.6 35.3 37.9 62.2 32.9 15.0 40.1 57.8 32.7 47.8 40.7 46.4 26.4 48.4 42.9 45.8 25.9 38.5 30.8 71.1 22.1 28.0 33.2 27.1 20.8 28.2 45.6 24.5 24.9 23.8 16.6 21.8 28.9 20.8 19.1 10.7 10.6 15.4 13.0 8.9 9.8 10.3 18.9 18.4 12.8 36.9 10.9 17.2 7.0 18.6 3.2 25.5 33.7 13.6 24.2 23.4 10.3 15.9 25.6 14.7 12.3 10.7 7.1 12.2 14.3 34.4 10.1 20.9 26.8 75.6 29.2 26.2 17.9 13.8 21.5 10.2 32.4 22.5 28.9 16.1 13.4 16.7 17.0 18.0 23.4 37.1 21.4 28.5 20.7 35.6 23.6 15.1 27.8 17.8 24.8 19.9 20.8 45.6 22.6 21.1 15.7 19.1 20.6 23.8 21.8 20.8 20.0 18.6 32.1 24.9 24.5 28.2 19.8 16.6 38.1 51.9 43.7 89.0 39.6 37.5 43.6 34.4 62.2 38.5 RAB11FIP2 "KIAA0941, nRip11, Rab11-FIP2" ENSG00000107560 "RAB11 family interacting protein 2" Q7L804 10 118004916-118046603 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037726 Approved Supported Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA037726: AB_10672390" "unprognostic (1.97e-1)" "unprognostic (1.68e-2)" "unprognostic (3.61e-1)" "unprognostic (4.45e-2)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.17e-2)" "unprognostic (3.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favourable (9.69e-5)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (2.17e-1)" 8.8 7.1 11.8 6.4 21.6 12.0 7.2 13.3 19.9 11.4 9.7 7.9 19.0 3.8 23.0 29.8 6.8 12.9 8.6 7.2 10.5 7.1 12.8 5.6 7.7 8.5 8.0 12.9 10.7 7.0 8.6 6.6 8.3 11.5 12.7 5.3 6.9 6.2 27.2 6.5 6.3 6.7 20.0 7.5 7.7 15.5 8.6 8.8 10.0 11.8 3.8 5.6 10.5 13.7 2.3 2.6 1.9 1.2 0.9 2.3 0.4 5.2 6.7 5.6 7.1 9.4 12.0 6.1 10.4 12.1 6.4 6.7 5.4 5.6 10.8 8.4 10.6 3.7 7.8 4.6 10.0 2.7 8.2 3.9 6.9 3.7 13.6 7.1 4.2 11.7 8.7 9.1 20.0 3.9 2.8 9.2 8.3 1.9 5.4 5.3 4.8 4.7 4.7 19.9 3.6 9.6 4.2 1.3 10.4 7.3 3.0 12.8 2.3 6.7 5.7 8.6 7.0 10.1 10.3 6.7 5.6 7.0 8.9 12.3 5.3 1.5 1.2 1.4 1.5 0.8 1.4 2.2 1.2 1.5 0.6 2.3 2.3 1.3 1.9 0.9 0.7 2.6 0.6 0.4 11.8 21.6 13.3 19.9 10.5 7.1 8.0 12.9 11.5 8.8 RAB11FIP5 "GAF1, KIAA0857, pp75, RIP11" ENSG00000135631 "RAB11 family interacting protein 5" Q9BXF6 2 73073382-73156721 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.4" "Cell line enhanced" "Detected in many" "TIME: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.6" "Lineage enriched" "Detected in single" 18 "T-cells: 2.6" "Low region specificity" "Detected in all" "HPA036406, HPA036407" Enhanced Enhanced "Vesicles,Centriolar satellite" "Vesicles, Centriolar satellite" "HPA036406: , HPA036407: AB_10669778" "unprognostic (1.49e-1)" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.58e-3)" "unprognostic (4.08e-3)" "unprognostic (2.27e-1)" "prognostic unfavourable (3.87e-4)" "unprognostic (3.23e-3)" "unprognostic (1.45e-1)" "prognostic favourable (2.26e-5)" "unprognostic (1.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "unprognostic (9.66e-3)" 8.4 5.4 5.3 3.8 9.3 1.5 6.3 9.5 16.7 5.2 4.2 2.8 4.6 3.5 7.9 7.3 5.3 5.6 8.2 7.2 4.9 6.3 14.9 2.3 4.8 2.1 5.6 6.5 6.7 8.4 22.3 4.3 11.4 16.0 5.3 2.1 5.1 9.5 5.9 9.0 5.8 2.6 5.2 2.9 18.9 4.9 46.4 2.5 0.0 3.9 4.7 2.7 5.3 7.4 0.1 0.0 0.0 0.0 0.0 2.6 0.5 12.0 5.4 0.4 3.8 4.0 4.8 7.0 18.2 10.0 6.2 4.8 3.9 3.0 0.0 9.6 9.2 4.9 2.3 5.6 2.8 20.9 6.7 4.4 2.3 2.5 4.9 0.0 0.8 5.8 5.3 7.6 5.0 8.5 3.4 2.4 4.4 0.3 0.0 0.1 2.9 8.6 4.1 4.9 10.2 5.4 1.5 1.8 1.9 6.0 2.5 2.7 1.4 0.2 25.0 15.1 8.8 11.2 9.5 7.9 2.3 0.0 11.8 4.7 1.4 0.0 0.0 0.0 2.6 0.0 0.5 0.0 1.2 1.9 0.0 0.1 0.2 1.5 0.0 0.0 0.0 0.0 0.8 0.5 5.3 9.3 9.5 16.7 4.9 6.3 5.6 6.5 16.0 2.5 RAB31 Rab22B ENSG00000168461 "RAB31, member RAS oncogene family" Q13636 18 9708165-9862551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 41.2;U-87 MG: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 36.9" "Group enriched" "Detected in many" 7 "dendritic cells: 13.7;granulocytes: 36.9;monocytes: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019717 Approved "HPA019717: AB_10601493" "unprognostic (4.61e-2)" "unprognostic (1.65e-2)" "unprognostic (8.53e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-2)" "unprognostic (5.70e-2)" "unprognostic (3.07e-2)" "unprognostic (5.99e-2)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.26e-2)" "unprognostic (3.98e-3)" "unprognostic (8.71e-3)" "unprognostic (1.61e-1)" "unprognostic (6.34e-2)" 17.5 52.5 35.1 19.9 33.2 25.6 11.5 10.1 53.9 45.2 16.7 19.8 6.2 5.7 28.7 11.3 16.1 11.6 22.7 9.9 27.1 24.3 7.6 5.4 28.1 17.5 31.0 17.8 22.6 3.8 2.3 4.2 27.1 25.0 10.2 9.2 8.0 5.9 25.0 3.4 5.2 8.7 41.5 39.2 16.0 15.1 20.4 23.0 2.6 12.5 7.2 10.9 25.0 15.1 3.1 13.7 36.9 16.5 1.3 0.0 5.3 0.6 3.5 26.7 0.0 35.5 18.5 19.1 6.3 17.8 4.6 4.0 1.0 3.6 0.0 4.3 24.6 2.5 6.5 8.1 5.4 1.6 3.8 21.9 27.5 0.4 41.2 1.8 24.2 19.9 1.7 10.7 8.3 11.8 5.3 0.1 10.7 2.9 0.0 2.8 5.7 1.6 0.0 2.9 0.9 3.5 0.0 0.5 1.7 24.0 15.3 8.5 1.7 11.9 13.0 29.0 14.8 19.8 9.2 5.0 1.4 0.0 39.5 0.0 11.8 36.9 16.5 6.2 0.0 14.2 0.0 3.1 0.0 0.0 13.7 1.7 0.0 0.0 23.1 1.3 14.5 1.6 0.0 5.3 35.1 33.2 10.1 25.1 27.1 24.3 31.0 17.8 25.0 23.0 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111629-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Supported "Nucleoplasm,Plasma membrane" 16000000 "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavourable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favourable (1.71e-4)" "unprognostic (9.99e-2)" 23.4 22.8 15.6 24.5 14.1 32.5 15.9 16.6 13.6 18.2 23.1 18.5 15.0 37.6 17.2 11.8 22.9 18.0 17.1 10.6 13.6 11.2 24.8 57.8 19.3 24.9 14.2 8.4 23.3 24.7 8.8 15.5 30.9 13.6 16.3 20.1 16.5 27.4 14.7 5.2 22.3 56.2 14.1 16.7 43.4 20.1 15.9 14.7 33.4 18.5 12.7 36.1 19.7 17.9 34.3 45.4 55.2 81.1 39.0 31.8 75.5 28.9 19.6 16.2 13.5 13.1 11.7 25.3 17.6 15.2 23.5 24.7 22.3 33.5 20.0 20.1 17.2 19.2 21.6 21.7 15.0 41.0 12.6 41.9 18.2 22.9 15.0 36.3 41.8 12.1 11.3 22.1 9.6 19.3 19.4 30.6 18.6 33.4 30.2 31.9 20.2 31.5 34.5 17.8 35.4 17.3 22.2 14.9 14.7 17.8 21.2 11.1 17.1 13.6 19.0 19.8 12.8 38.4 30.0 16.7 34.1 30.1 19.1 36.4 21.3 36.0 50.6 55.2 31.8 69.8 28.4 34.3 28.4 28.6 45.4 31.8 22.5 26.5 53.8 39.0 81.1 32.5 26.6 75.5 15.6 14.1 16.6 13.6 13.6 11.2 14.2 8.4 13.6 14.7 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.1 17.4 26.6 20.5 23.1 18.7 53.5 23.1 39.2 30.6 34.8 13.6 12.5 15.9 11.1 35.8 9.7 28.0 20.5 31.9 27.7 21.9 21.4 21.0 12.6 23.4 20.8 20.3 17.2 20.7 31.5 25.6 21.9 15.5 41.8 29.5 25.9 26.7 15.3 27.0 23.7 21.6 23.4 20.0 18.3 22.9 8.3 17.5 18.9 18.3 12.3 30.4 27.5 15.7 21.1 20.1 17.6 25.7 32.6 51.8 34.2 18.2 24.3 22.4 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic alpha subunit 1" Q6GYQ0 14 35538352-35809304 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved Mitochondria,Cytosol Cytosol Mitochondria "HPA000851: AB_1078945" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (8.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-2)" "unprognostic (7.65e-2)" "unprognostic (1.17e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-2)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "prognostic favourable (9.76e-5)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" 13.9 21.8 19.5 13.1 25.6 8.3 22.5 31.7 28.3 20.2 18.3 23.2 13.6 10.7 21.0 19.2 15.1 15.0 13.0 11.7 21.8 22.2 17.1 13.9 13.4 11.7 21.5 17.9 28.1 15.4 43.6 42.6 10.1 28.1 20.4 20.2 14.2 15.0 15.2 15.9 27.0 13.8 17.5 23.6 11.6 14.1 13.7 21.3 14.9 21.3 12.2 13.0 15.0 19.2 1.6 1.5 0.1 1.1 2.3 3.3 0.5 5.7 6.7 9.0 7.9 13.7 10.6 5.8 4.3 4.8 5.4 5.0 4.2 5.1 5.7 6.4 5.6 9.5 10.8 8.2 5.5 12.1 4.7 5.2 8.6 20.1 7.1 8.6 8.4 7.6 14.9 4.8 12.0 7.5 5.0 14.4 5.0 9.1 6.5 4.1 3.9 10.7 5.3 6.4 3.4 10.9 9.1 8.4 13.7 9.1 15.2 7.3 14.6 4.2 6.9 5.5 4.1 6.2 5.2 11.7 10.6 7.2 2.6 5.7 5.9 0.0 0.6 0.1 2.4 1.1 3.3 1.6 2.5 3.1 1.1 1.3 1.8 2.5 0.1 2.3 0.9 1.5 2.7 0.5 19.5 25.6 31.7 26.0 21.8 22.2 21.5 17.9 28.1 21.3 RAP1A "KREV-1, SMGP21" ENSG00000116473 "RAP1A, member of RAS oncogene family" P62834 1 111542218-111716691 "Predicted intracellular proteins, RAS pathway related proteins" Neurogenesis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" 150000000 "unprognostic (7.37e-3)" "unprognostic (7.49e-2)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.88e-2)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" "unprognostic (6.10e-2)" "unprognostic (4.98e-3)" "unprognostic (1.54e-2)" "unprognostic (1.84e-1)" "unprognostic (3.44e-2)" "unprognostic (1.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (3.08e-1)" 28.9 20.3 26.7 31.6 30.2 23.1 22.0 15.3 22.8 26.5 65.2 26.8 24.8 21.8 27.2 28.4 41.7 22.5 36.0 56.3 28.1 21.8 23.5 31.4 27.9 33.4 34.4 15.2 16.5 13.1 44.0 23.9 21.1 25.7 32.5 32.0 13.1 21.4 34.4 32.3 14.0 27.2 74.6 48.9 32.3 35.5 9.7 28.8 24.9 23.0 19.7 38.9 70.4 48.1 10.1 16.2 30.5 14.0 13.4 19.5 11.5 33.6 5.3 13.2 7.7 27.0 26.1 12.2 22.5 24.0 16.3 18.5 17.5 14.1 27.6 15.9 28.1 12.3 12.1 16.9 30.5 102.6 12.5 20.0 13.4 10.7 27.6 20.8 20.9 16.9 19.8 18.1 19.0 21.4 15.1 30.7 22.4 15.4 10.7 26.5 7.8 14.2 11.8 28.1 13.7 26.0 17.1 9.4 6.7 27.6 16.3 20.3 8.2 26.7 20.0 13.2 16.9 16.5 21.8 32.9 11.0 30.4 18.4 32.0 34.5 7.8 13.9 12.7 11.4 14.0 13.3 10.1 19.5 17.1 16.2 6.4 14.9 14.0 30.5 13.4 12.6 8.1 17.2 11.5 26.7 30.2 15.3 22.8 28.1 21.8 34.4 15.2 25.7 28.8 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734367-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 21.8;HUVEC TERT2: 9.3;NB-4: 10.7;RPTEC TERT1: 10.5;TIME: 9.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Approved Cytosol Cytosol "CAB004386: AB_627521, HPA040365: , HPA043518: " "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favourable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 26.5 2.8 18.2 3.0 19.7 1.9 22.1 3.9 23.0 12.7 4.8 28.8 19.4 4.7 10.6 11.9 10.4 15.9 13.7 15.9 20.7 7.3 22.8 1.6 6.9 4.7 24.2 14.9 30.9 5.4 4.9 3.0 9.8 19.1 7.1 3.2 3.3 20.5 16.9 10.6 6.9 4.8 6.0 12.0 10.9 6.3 2.5 27.4 0.0 27.3 4.8 2.7 8.6 11.5 1.1 0.6 0.5 0.7 0.0 1.2 0.4 1.7 0.5 0.6 1.9 0.2 1.8 0.6 1.3 1.0 0.5 0.3 0.2 4.6 0.1 21.8 2.3 1.9 0.7 3.3 0.2 2.3 0.3 0.2 1.6 0.1 0.1 0.3 0.2 0.7 0.3 1.0 0.6 9.3 0.1 2.3 0.4 1.1 0.0 10.7 0.5 3.0 0.3 0.1 0.7 10.5 2.0 0.2 0.3 0.2 1.3 0.3 5.0 0.4 9.3 5.4 0.9 1.2 0.4 1.0 0.3 0.1 3.3 2.3 0.5 0.0 0.7 0.0 0.1 0.4 0.6 0.5 0.1 1.2 0.3 1.1 0.2 0.3 0.5 0.0 0.5 0.6 0.4 0.4 18.2 19.7 3.9 23.0 20.7 7.3 24.2 14.9 19.1 27.4 RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341674 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 145.8;liver: 184.8;pancreas: 145.4" "Group enriched" "Detected in some" 6 "AF22: 27.1;Hep G2: 39.3;HHSteC: 35.5;NTERA-2: 82.8" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "plasmacytoid DC: 8.2" "Lineage enriched" "Detected in single" 10 "dendritic cells: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" 75000000 550000000 "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavourable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavourable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" 46.5 145.8 4.6 20.5 5.0 0.0 28.0 2.6 4.4 51.2 31.0 10.7 10.9 5.0 23.8 21.0 18.3 21.9 30.5 12.9 5.3 3.6 21.9 184.8 33.2 10.7 7.6 3.0 40.2 145.4 66.7 6.3 5.6 12.0 35.5 8.0 23.5 6.1 12.2 7.4 3.2 10.3 27.5 7.7 11.0 10.9 11.1 5.4 1.0 7.8 5.2 10.5 26.3 39.7 0.1 8.2 0.0 0.0 0.8 0.3 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.3 2.1 5.1 0.8 3.5 0.2 1.6 0.2 3.1 0.5 0.1 0.0 0.0 0.0 0.4 0.1 0.1 4.4 39.3 35.5 0.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.5 82.8 0.0 0.0 3.6 0.0 0.6 0.2 0.1 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 8.2 0.0 0.0 4.6 5.0 2.6 4.4 5.3 3.6 7.6 3.0 12.0 5.4 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 897.1" "Cell line enriched" "Detected in some" 4 "Hep G2: 151.8" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 14 "classical monocyte: 1.2;myeloid DC: 1.5" "Group enriched" "Detected in many" 14 "dendritic cells: 1.5;monocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001641, CAB004555" Supported "Secreted to blood" 46066666667 420000000000 "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favourable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 39.0 2.0 1.4 2.4 3.1 0.3 27.0 0.0 2.1 0.3 1.8 0.0 0.1 0.5 0.4 0.4 0.3 0.4 2.1 1.2 1.4 2.2 7.9 897.1 1.5 1.0 0.2 1.1 0.5 4.7 0.3 28.3 1.8 0.4 0.9 0.6 5.6 1.8 0.5 0.4 0.4 0.6 0.3 0.1 0.3 0.7 0.4 0.0 0.0 0.3 0.5 0.2 0.6 1.6 0.0 1.5 0.0 1.2 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 36.6 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 151.8 0.0 1.2 0.0 2.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.2 17.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 3.1 0.0 2.1 1.4 2.2 0.2 1.1 0.4 0.0 REST "NRSF, XBR" ENSG00000084093 "RE1 silencing transcription factor" Q13127 4 56907876-56966678 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006079, CAB068222" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB068222: , HPA006079: AB_1079801" "unprognostic (7.49e-3)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (7.47e-3)" "unprognostic (2.30e-1)" "unprognostic (4.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.32e-3)" "unprognostic (1.73e-1)" "prognostic favourable (9.50e-5)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" 14.4 11.4 6.0 15.6 8.9 21.5 39.7 2.1 6.3 13.7 11.0 5.6 13.0 6.5 14.2 13.7 14.5 11.2 13.8 22.1 6.1 4.5 13.9 12.0 18.2 35.6 8.2 3.0 13.9 15.9 22.4 4.5 14.4 11.8 17.3 7.6 7.2 14.0 27.6 13.8 11.6 12.0 16.3 15.2 18.7 10.4 15.3 8.2 43.4 13.4 8.3 14.0 15.6 19.5 16.7 10.7 9.0 8.4 16.7 15.3 4.2 7.0 9.0 12.5 12.4 9.4 11.9 15.8 10.5 9.4 11.3 10.3 8.9 10.9 16.9 16.9 11.4 6.5 9.2 11.1 17.8 8.9 5.5 15.4 7.1 7.9 11.5 19.4 9.2 11.7 10.0 10.8 11.2 13.9 9.8 18.2 13.0 11.2 22.3 13.2 10.6 5.9 19.8 10.7 5.2 12.8 12.8 0.2 5.7 12.7 12.4 9.4 13.2 12.7 19.6 14.4 12.8 8.0 9.4 7.3 5.4 10.2 9.2 11.0 7.4 9.0 3.6 7.7 10.6 5.3 8.9 12.0 10.5 10.4 8.1 16.7 15.3 9.3 3.7 16.7 8.4 10.7 10.3 4.2 6.0 8.9 2.1 6.3 6.1 4.5 8.2 3.0 11.8 8.2 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669044-7670454 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 45.5;bone marrow: 79.5;lymphoid tissue: 27.6" "Group enriched" "Detected in some" 11 "NB-4: 100.1;U-937: 46.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 4.8" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "classical monocyte: 45.5;myeloid DC: 30.3" "Group enriched" "Detected in many" 11 "dendritic cells: 30.3;monocytes: 45.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" 6440000 350000 "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 1.3 0.4 0.0 1.9 0.6 79.5 0.6 0.4 0.9 0.1 0.2 0.1 0.7 2.3 0.3 0.1 0.2 1.3 0.2 21.9 0.0 0.0 0.9 1.6 17.3 7.5 1.3 0.0 0.8 1.6 0.1 0.4 1.1 0.2 0.2 0.1 0.7 0.7 0.1 0.6 0.2 0.3 1.5 0.4 27.6 0.4 0.4 0.5 2.7 0.8 0.0 0.4 0.2 2.3 0.0 30.3 3.4 45.5 0.0 2.4 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 100.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.0 45.5 0.0 0.1 21.7 0.3 0.0 0.5 0.4 30.3 0.0 1.1 2.4 3.4 0.0 11.1 1.2 0.0 14.0 0.0 0.6 0.4 0.9 0.0 0.0 1.3 0.0 0.2 0.5 RFX3 ENSG00000080298 "Regulatory factor X3" P48380 9 3218297-3526004 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.1;testis: 36.5" "Cell line enhanced" "Detected in many" "AF22: 21.9;HDLM-2: 12.9;SCLC-21H: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035689 Enhanced Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA035689: AB_10671224" "prognostic favourable (1.47e-4)" "unprognostic (8.78e-2)" "unprognostic (1.18e-1)" "unprognostic (5.52e-2)" "unprognostic (2.27e-2)" "unprognostic (1.50e-1)" "unprognostic (8.26e-3)" "unprognostic (3.06e-2)" "unprognostic (1.68e-1)" "unprognostic (6.49e-2)" "unprognostic (7.58e-3)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-1)" "unprognostic (2.52e-1)" "unprognostic (8.89e-3)" 5.2 4.6 17.9 7.6 14.9 11.4 6.7 35.1 19.5 6.9 4.7 6.9 5.0 5.0 6.8 6.3 3.8 22.0 5.2 4.0 12.8 7.5 5.0 4.1 7.2 6.7 6.0 11.9 7.0 5.4 9.0 21.7 5.8 9.9 6.1 5.6 4.2 4.7 4.6 5.7 4.4 5.0 4.0 12.5 5.7 6.6 36.5 11.0 12.7 5.7 2.9 7.5 4.5 7.8 8.3 4.6 8.9 4.8 5.3 9.3 3.2 1.9 2.7 21.9 5.3 0.9 1.0 2.2 0.8 2.3 1.9 1.4 0.8 2.5 3.1 0.9 1.1 1.1 5.3 2.2 3.3 12.9 1.4 5.9 2.9 1.8 1.1 1.2 0.8 1.3 1.0 2.3 3.7 3.2 1.1 3.2 2.0 1.5 3.7 4.3 5.8 1.1 3.9 1.5 0.8 3.0 1.6 11.8 5.2 1.3 0.6 2.0 1.1 3.1 2.0 1.4 3.2 0.7 1.3 1.1 0.5 6.3 1.5 1.4 1.4 3.5 3.2 6.2 8.8 4.8 5.4 6.3 8.1 7.2 3.1 8.3 5.7 7.0 8.9 5.3 1.4 4.6 9.3 3.2 17.9 14.9 35.1 19.5 12.8 7.5 6.0 11.9 9.9 11.0 RHEB RHEB2 ENSG00000106615 "Ras homolog, mTORC1 binding" Q15382 7 151466012-151520120 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019436 Uncertain 24000 "CAB019436: AB_2178777" "unprognostic (2.22e-2)" "unprognostic (2.29e-2)" "unprognostic (2.25e-2)" "unprognostic (9.47e-2)" "unprognostic (2.65e-2)" "unprognostic (3.08e-3)" "prognostic unfavourable (9.08e-5)" "unprognostic (9.37e-2)" "unprognostic (4.76e-3)" "unprognostic (9.76e-3)" "unprognostic (1.85e-3)" "unprognostic (3.67e-2)" "unprognostic (2.36e-3)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.15e-1)" 21.8 37.2 30.9 15.1 32.4 23.8 28.0 21.1 34.6 16.5 22.3 14.6 26.7 13.3 24.2 44.4 18.3 15.4 14.9 26.2 31.4 29.3 25.0 27.4 19.8 9.8 28.9 18.2 18.7 20.4 19.0 48.6 37.0 27.3 21.0 16.1 24.8 20.4 27.1 34.2 11.5 13.4 30.0 29.7 15.2 17.1 15.8 25.4 10.8 40.6 12.8 11.6 19.6 14.1 16.5 32.2 30.9 24.3 23.5 30.1 26.0 57.1 17.5 31.0 29.4 38.7 31.8 23.4 42.3 37.4 35.6 43.5 25.1 62.4 14.8 66.7 37.4 19.5 22.2 20.4 46.3 15.6 17.1 12.6 21.4 18.7 60.5 23.3 20.7 24.3 32.8 28.3 38.2 27.4 39.0 68.9 49.0 37.0 32.9 33.4 50.8 25.5 16.0 27.3 29.8 41.3 20.6 29.8 37.5 43.0 41.8 47.8 15.6 29.3 29.9 28.2 11.7 48.6 68.0 25.9 35.3 21.3 68.2 43.8 76.2 22.7 24.3 30.9 18.5 20.6 30.1 16.5 25.7 23.1 18.4 15.1 18.8 23.2 23.9 23.5 22.3 32.2 24.9 26.0 30.9 32.4 21.1 34.2 31.4 29.3 28.9 18.2 27.3 25.4 RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886703-72403143 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 83.1" "Cell line enhanced" "Detected in some" "Daudi: 4.8;EFO-21: 8.7;LHCN-M2: 9.6;RPTEC TERT1: 14.8;SH-SY5Y: 10.4;TIME: 5.1;U-138 MG: 5.0" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enriched" "Detected in all" 6 "cerebellum: 83.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076565 Enhanced "HPA076565: " "unprognostic (1.34e-3)" "unprognostic (3.47e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (6.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (2.85e-1)" "unprognostic (7.76e-4)" "unprognostic (2.42e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (5.74e-2)" "unprognostic (1.07e-2)" 0.5 2.3 10.5 1.5 9.8 0.4 1.2 83.1 27.7 0.9 0.6 0.5 0.0 1.5 0.8 0.5 3.7 0.5 6.2 0.6 9.3 3.6 0.5 0.4 0.7 0.5 2.8 11.7 0.5 0.8 5.0 4.6 0.4 7.2 4.9 0.6 0.2 1.9 0.9 0.6 0.4 0.8 1.4 1.5 0.4 1.4 5.9 2.7 0.0 0.5 0.0 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.0 0.2 1.3 0.0 0.1 0.0 0.0 4.8 8.7 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.4 14.8 0.0 0.4 10.4 0.0 0.0 0.0 0.6 0.0 5.1 5.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 9.8 83.1 12.9 9.3 3.6 2.8 11.7 7.2 2.7 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500748-104256094 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1;brain: 28.7" "Cell line enhanced" "Detected in some" "AF22: 6.0;Daudi: 11.7;RT4: 8.4;SCLC-21H: 20.7;U-2 OS: 5.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: " "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.9 51.1 15.8 1.0 21.8 1.1 1.8 14.5 28.7 8.5 0.9 0.5 0.9 1.2 1.4 1.7 1.0 6.3 1.7 0.9 10.3 4.9 1.1 0.9 1.0 1.1 3.1 17.5 2.8 1.6 0.9 12.4 1.1 8.6 2.8 1.0 5.8 1.0 1.8 1.0 1.0 1.4 2.0 4.0 0.9 1.7 3.9 8.7 0.0 2.9 0.0 1.0 1.5 1.6 0.7 0.7 2.9 0.6 1.6 0.6 0.2 3.7 0.0 6.0 0.0 0.0 0.0 0.0 0.4 0.3 1.1 1.4 0.1 0.3 11.7 0.1 0.0 0.3 1.8 0.7 1.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.9 0.0 0.1 0.5 0.0 0.5 0.8 0.0 4.6 0.6 0.0 0.0 0.0 0.0 8.4 20.7 5.0 0.0 0.1 0.5 0.3 0.2 0.0 0.0 5.5 0.1 0.1 1.5 0.0 0.1 0.4 0.2 0.2 2.7 0.6 0.6 0.6 0.3 0.4 0.4 0.3 0.4 0.1 0.7 0.3 0.5 2.9 1.6 0.4 0.7 0.3 0.2 15.8 21.8 14.5 28.7 10.3 4.9 3.1 17.5 8.6 8.7 RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334969-5339873 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "prostate: 25.4" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;HEL: 4.7;SK-BR-3: 1.0" "Cancer enriched" "Detected in some" 106 "prostate cancer: 67.0" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Cell type enhanced" "Detected in single" "gdT-cell: 1.6" "Lineage enriched" "Detected in single" 13 "T-cells: 1.6" "Secreted to blood" "unprognostic (7.12e-6)" "unprognostic (2.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (4.08e-4)" "unprognostic (8.15e-2)" "unprognostic (2.89e-4)" "unprognostic (8.82e-3)" "unprognostic (3.23e-2)" "unprognostic (3.23e-2)" "unprognostic (1.53e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.1 0.9 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 2.1 0.0 0.0 0.0 0.0 0.0 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299868-5304969 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 44.0" "Cell line enhanced" "Detected in some" "Daudi: 5.1;HEL: 19.7;T-47d: 5.7;U-266/84: 9.0" "Cancer enhanced" "Detected in some" "prostate cancer: 6.7" "Region enriched" "Detected in single" 64 "basal ganglia: 44.0" "Group enriched" "Detected in many" 39 "gdT-cell: 2.1;MAIT T-cell: 6.5;memory B-cell: 2.8;memory CD4 T-cell: 4.3;memory CD8 T-cell: 3.5;naive B-cell: 2.1;naive CD4 T-cell: 6.2;naive CD8 T-cell: 4.6;NK-cell: 4.9;T-reg: 2.0" "Group enriched" "Detected in many" 47 "B-cells: 2.8;NK-cells: 4.9;T-cells: 6.5" "Secreted to blood" 24440 "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.6 0.0 0.6 1.6 44.0 0.0 3.2 0.6 0.6 0.6 0.6 0.6 0.6 0.0 0.6 0.6 0.6 7.5 0.6 0.6 0.6 0.6 2.0 0.6 0.7 3.5 0.6 0.6 0.6 0.9 5.2 5.8 0.7 0.6 6.2 0.3 0.6 0.6 0.7 0.6 0.4 0.8 0.6 0.6 1.4 0.4 4.2 0.6 0.6 0.9 0.6 3.0 0.6 0.6 2.8 0.0 0.0 0.0 4.9 6.5 1.4 2.8 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.9 0.3 1.5 5.1 0.4 0.0 0.9 0.0 2.6 0.7 4.0 1.9 19.7 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.2 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.5 2.6 2.9 0.0 0.6 0.1 5.7 0.1 0.2 0.0 0.5 0.0 0.1 1.3 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 6.5 2.8 4.3 3.5 0.0 2.1 6.2 4.6 0.0 4.9 0.0 0.0 2.0 1.4 0.6 44.0 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002633, CAB010906" Approved Supported Cytosol Cytosol "CAB010906: AB_477444, HPA002633: AB_1856314" "unprognostic (3.46e-2)" "unprognostic (9.10e-2)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" 8.1 10.8 7.4 9.5 10.9 3.7 8.3 5.7 7.7 12.5 9.3 6.7 8.5 8.0 12.4 11.9 10.0 8.8 8.0 5.8 7.0 5.3 9.9 3.9 8.4 10.1 7.7 3.3 14.0 5.3 13.5 18.0 8.5 10.1 10.5 10.8 13.3 10.5 10.3 4.1 6.3 12.2 9.6 7.4 10.5 8.8 3.5 6.7 13.3 13.3 2.8 11.0 13.9 11.0 5.0 7.2 26.9 13.5 5.0 9.2 4.9 2.3 3.3 1.4 0.5 7.6 13.3 2.6 4.5 5.6 4.6 4.3 1.9 5.1 5.1 7.9 5.1 4.3 3.3 4.6 1.8 4.0 2.8 5.9 1.2 0.2 3.9 11.0 11.7 9.4 10.6 2.4 0.7 2.0 2.1 3.9 4.0 3.3 3.2 4.6 1.1 0.9 4.8 1.1 2.6 4.9 3.1 0.7 0.2 4.0 4.9 3.8 5.0 12.3 2.5 2.4 1.9 2.5 2.4 3.5 1.2 0.6 3.8 6.8 3.5 16.8 7.2 24.6 4.9 7.6 6.4 5.0 5.8 5.2 6.0 3.8 9.2 6.7 26.9 5.0 13.5 7.2 4.6 4.9 7.4 10.9 5.7 7.7 7.0 5.3 7.7 3.3 10.1 6.7 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117288300-117425855 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 38.6;lung: 20.2" "Group enriched" "Detected in some" 5 "HSkMC: 9.3;hTCEpi: 19.3;LHCN-M2: 13.4" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 7.4;olfactory region: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles Vesicles "HPA049098: , HPA072424: " "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.3 0.2 0.2 0.0 0.4 0.0 0.2 0.2 7.4 0.2 0.4 0.0 7.9 0.0 0.2 38.6 0.2 0.2 0.0 0.2 0.2 0.2 0.4 0.2 20.2 0.0 0.2 2.5 0.2 0.2 0.0 0.3 0.7 0.0 0.2 0.3 0.0 0.2 2.3 0.2 0.7 0.3 0.0 0.2 0.2 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 9.3 19.3 0.2 1.7 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.8 0.0 2.3 1.5 0.1 1.8 0.0 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 7.4 0.2 0.2 0.2 2.5 0.0 0.0 RPE65 "BCO3, LCA2, rd12, RP20" ENSG00000116745 "RPE65, retinoid isomerohydrolase" Q16518 1 68428822-68449959 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Isomerase" "Disease mutation, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "retina: 268.3" "Cell line enhanced" "Detected in some" "A-431: 6.0;PC-3: 10.4;U-2 OS: 2.5" "Group enriched" "Detected in some" 10 "glioma: 5.8;head and neck cancer: 1.5" "Group enriched" "Detected in many" 5 "hypothalamus: 6.0;midbrain: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "unprognostic (1.59e-1)" "unprognostic (1.88e-1)" "unprognostic (3.15e-1)" "prognostic favourable (9.75e-4)" "unprognostic (4.55e-2)" "unprognostic (5.91e-2)" "unprognostic (6.59e-4)" "unprognostic (2.98e-2)" "unprognostic (1.57e-1)" "unprognostic (8.24e-2)" "unprognostic (3.21e-4)" "unprognostic (2.11e-1)" "unprognostic (2.05e-1)" "unprognostic (3.48e-2)" "unprognostic (8.40e-3)" 0.0 0.0 0.9 0.1 0.7 0.0 1.0 0.1 3.8 0.2 0.1 1.3 1.4 0.4 1.4 0.7 0.8 0.6 0.2 0.0 1.5 6.0 0.0 0.0 0.0 0.1 8.8 0.1 0.1 0.0 0.0 0.0 0.0 1.2 4.2 0.2 268.3 0.2 10.5 0.0 0.0 0.1 0.5 1.4 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.6 1.5 6.0 8.8 0.1 1.2 0.6 RPH3AL Noc2 ENSG00000181031 "Rabphilin 3A like (without C2 domains)" Q9UNE2 17 212389-386254 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 58.9" "Cell line enhanced" "Detected in many" "A549: 20.3;PC-3: 6.6;TIME: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024311 Approved "HPA024311: AB_1856429" "unprognostic (4.55e-2)" "unprognostic (1.66e-1)" "unprognostic (3.85e-2)" "unprognostic (9.43e-3)" "unprognostic (8.40e-2)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (6.71e-2)" "unprognostic (1.02e-1)" "unprognostic (2.24e-3)" "unprognostic (1.33e-2)" "prognostic favourable (1.03e-8)" "unprognostic (9.10e-2)" "unprognostic (1.63e-2)" "unprognostic (4.14e-1)" "unprognostic (3.59e-3)" 10.2 8.4 0.5 4.1 0.8 0.2 12.3 2.1 1.7 2.4 7.9 0.7 2.9 4.9 1.8 4.7 5.8 2.6 4.7 1.6 0.6 1.3 9.4 11.2 8.8 1.1 1.0 1.0 5.0 27.5 1.2 58.9 3.8 4.9 4.0 2.6 3.7 1.3 2.4 7.5 1.7 6.5 2.8 2.6 7.8 5.1 1.1 0.9 0.4 14.8 5.3 4.2 3.1 7.6 1.6 6.2 3.4 5.0 0.7 1.9 0.8 0.3 20.3 0.3 0.1 0.2 0.1 1.8 0.1 0.0 0.0 0.1 2.8 3.6 0.4 3.0 1.9 0.3 0.8 0.2 0.0 0.9 1.3 0.0 1.6 4.4 0.6 0.2 2.2 0.0 0.1 0.0 0.0 0.8 1.4 4.3 1.2 4.7 0.3 0.1 1.1 6.6 0.4 0.2 3.8 3.9 4.6 0.3 0.7 0.3 0.1 0.3 1.9 1.9 6.8 0.3 3.1 0.5 0.6 0.7 0.2 0.2 0.3 2.8 0.1 1.0 1.6 3.3 1.9 5.0 0.9 1.4 1.1 1.6 2.6 1.6 1.7 0.9 3.4 0.7 3.4 6.2 0.8 0.8 0.5 0.8 2.1 1.7 0.6 1.3 1.0 1.0 4.9 0.9 RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Enhanced Vesicles,Lysosomes "Vesicles, Lysosomes" "CAB013514: AB_2533523, HPA064306: " "unprognostic (5.09e-3)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (9.75e-2)" "unprognostic (3.34e-3)" "unprognostic (1.17e-2)" "unprognostic (9.63e-2)" "unprognostic (8.80e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-2)" 13.6 12.3 10.5 11.1 14.5 10.2 9.3 17.5 21.0 12.6 13.1 19.0 9.6 12.2 15.0 9.3 14.2 12.5 8.0 15.5 10.8 10.5 8.3 12.9 11.0 9.0 12.2 9.9 12.8 9.8 14.3 14.1 9.7 12.7 12.0 7.4 15.2 10.4 13.9 23.7 12.3 11.0 13.6 9.5 11.6 11.1 10.3 12.7 16.7 10.2 11.1 11.9 14.3 10.5 2.1 1.9 3.1 2.4 1.7 3.8 1.2 9.6 19.3 4.6 8.2 6.6 5.7 8.6 7.3 6.7 11.6 8.7 15.1 8.6 8.1 5.8 8.9 5.9 7.4 9.8 6.6 2.9 12.0 12.5 10.7 13.6 6.7 11.2 8.9 8.4 6.7 11.9 6.9 11.5 15.5 3.3 6.5 5.3 10.7 4.7 4.9 15.5 5.1 8.4 6.6 3.4 11.0 9.1 9.2 8.9 14.3 8.1 9.3 8.2 5.2 24.5 10.4 7.7 9.3 5.2 1.9 8.0 14.9 5.9 14.9 3.1 0.9 0.0 3.8 2.4 2.5 2.1 1.6 1.8 1.9 1.1 2.3 2.2 0.0 1.7 1.3 1.1 3.6 1.2 10.5 14.5 17.5 21.0 10.8 10.5 12.2 9.9 12.7 12.7 S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 375.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" 5100000 "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: AB_1079859" "unprognostic (8.80e-3)" "unprognostic (6.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (1.66e-1)" "unprognostic (3.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "prognostic favourable (7.56e-4)" 126.4 32.6 14.8 104.9 29.9 73.8 223.6 13.3 14.6 95.4 176.8 10.1 51.2 70.2 65.0 135.5 126.5 42.2 264.5 112.3 13.0 22.5 103.4 6.0 151.9 61.5 45.6 7.9 38.1 13.5 0.5 17.7 100.1 27.3 85.1 85.5 28.5 58.7 55.2 59.1 45.1 98.1 88.9 35.5 27.5 69.9 29.6 17.8 4.9 76.9 183.0 36.2 150.9 145.0 30.7 130.1 303.7 180.7 9.1 69.2 201.7 77.6 86.9 0.0 7.2 146.3 189.8 0.2 95.2 237.8 48.3 63.4 6.0 162.4 0.1 30.2 141.3 33.7 1.5 136.7 22.8 31.9 0.0 16.2 58.1 5.3 55.4 0.7 11.2 88.5 113.7 51.7 89.5 107.1 0.0 0.1 120.3 11.7 0.2 6.6 0.1 143.0 0.0 10.8 28.1 375.0 72.1 22.4 3.9 129.5 131.9 97.9 18.1 25.2 156.4 46.7 12.2 95.3 154.5 0.2 0.2 0.2 181.3 17.4 99.6 139.8 180.7 74.1 62.0 96.8 67.3 30.7 58.5 60.3 130.1 17.2 37.3 49.5 303.7 9.1 86.9 68.3 69.2 201.7 14.8 29.9 13.3 14.6 13.0 22.5 45.6 7.9 27.3 17.8 SCAP KIAA0199 ENSG00000114650 "SREBF chaperone" Q12770 3 47413694-47477126 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004713 Approved "HPA004713: AB_1079868" "unprognostic (4.02e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (4.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.74e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-2)" "unprognostic (7.10e-2)" "prognostic favourable (7.14e-4)" "unprognostic (4.07e-2)" "prognostic favourable (4.33e-5)" "unprognostic (3.15e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-3)" 11.1 47.4 15.9 10.7 21.4 11.3 15.0 23.7 28.7 13.8 18.2 22.6 13.9 17.8 17.7 14.8 17.8 16.0 14.5 10.9 16.9 11.5 13.5 34.1 11.3 17.1 15.6 12.2 18.8 22.1 26.3 15.2 16.9 17.3 13.1 16.0 19.3 16.0 14.2 15.6 26.2 17.1 14.9 11.6 15.0 15.5 19.5 18.5 18.8 15.4 9.4 12.0 18.5 13.6 6.7 7.7 18.3 6.4 7.5 10.5 4.7 10.5 14.9 16.2 24.9 29.3 15.5 28.7 10.3 15.3 17.3 16.4 19.8 17.3 17.5 15.1 17.6 11.4 22.6 21.8 18.0 12.0 16.3 30.2 20.9 21.3 28.5 18.0 18.1 19.4 23.4 21.9 24.2 14.7 20.5 12.2 13.9 14.8 19.7 26.7 16.8 22.2 11.6 14.8 21.0 13.7 20.8 11.2 20.8 15.2 19.3 10.0 16.8 19.9 12.6 16.0 19.1 21.9 14.4 12.1 13.1 10.2 15.1 16.7 11.7 5.8 6.4 6.7 7.8 5.7 10.5 6.6 6.6 7.0 7.7 6.7 7.5 7.3 18.3 7.5 4.5 6.2 8.0 4.7 15.9 21.4 23.7 28.7 16.9 11.5 15.6 12.2 17.3 18.5 SELENOS "AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP" ENSG00000131871 "Selenoprotein S" Q9BQE4 15 101270817-101277500 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "plasmacytoid DC: 96.1" "Lineage enriched" "Detected in all" 5 "dendritic cells: 96.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010025 Approved Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA010025: AB_1079900" "unprognostic (1.90e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "prognostic favourable (1.33e-4)" "unprognostic (2.42e-2)" "unprognostic (3.74e-3)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (9.83e-2)" "prognostic favourable (5.19e-4)" "unprognostic (2.42e-3)" "unprognostic (4.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" "unprognostic (2.66e-2)" 25.1 34.7 16.3 19.6 17.1 18.0 38.3 11.4 15.6 22.8 33.7 20.7 51.6 33.2 21.6 33.7 24.8 20.5 21.9 35.0 15.6 14.6 30.9 58.2 27.0 24.5 24.6 13.4 19.3 80.9 14.6 27.5 38.2 21.2 23.5 37.8 16.5 58.0 42.1 28.3 20.6 41.5 21.8 26.8 27.5 26.8 44.4 18.7 9.7 34.0 22.5 26.4 21.0 30.9 10.0 96.1 17.5 14.8 14.3 17.2 9.6 9.3 14.9 13.4 11.9 29.5 20.9 11.2 28.6 21.9 20.0 20.2 17.7 22.8 7.1 10.6 25.3 26.7 14.5 12.9 13.1 12.9 19.4 12.0 13.4 18.3 46.8 9.0 13.9 18.2 36.9 13.3 39.8 14.9 12.0 81.0 21.3 15.1 6.5 14.0 10.2 9.7 8.4 11.0 15.5 20.1 22.5 7.6 19.1 19.9 18.8 39.8 14.0 20.5 15.7 18.9 12.4 25.3 21.7 58.8 49.1 10.3 20.6 10.8 22.7 17.5 10.8 12.3 16.0 12.9 15.4 10.0 12.4 17.2 9.3 7.0 9.4 14.0 3.7 14.3 14.8 96.1 10.9 9.6 16.3 17.1 11.4 15.6 15.6 14.6 24.6 13.4 21.2 18.7 SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630445 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved "HPA039780: AB_10805594" "unprognostic (1.13e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (2.65e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-3)" "unprognostic (6.30e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-3)" "unprognostic (4.91e-2)" "unprognostic (4.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" 29.7 52.6 39.9 32.1 44.1 54.5 31.0 33.9 48.2 29.9 29.7 37.7 26.7 29.7 29.2 41.8 30.3 31.2 23.5 32.7 41.6 47.4 47.0 52.5 31.1 44.5 41.3 28.2 27.7 34.2 30.6 46.6 50.8 48.0 31.8 36.7 30.2 31.5 33.0 30.5 20.0 38.5 33.4 50.0 49.8 28.5 23.6 31.9 32.3 45.7 23.0 43.2 34.3 23.1 32.1 34.0 54.5 43.2 26.5 42.3 71.0 47.9 19.9 12.9 11.5 19.9 19.5 24.4 38.2 28.3 26.5 18.1 31.5 28.3 27.2 39.1 28.3 16.6 20.0 23.9 40.8 22.7 16.7 28.3 12.2 14.7 21.8 16.6 21.5 16.8 19.2 23.6 20.6 28.6 6.5 80.3 38.6 29.5 22.0 9.6 13.8 21.4 15.9 16.2 45.3 22.9 28.8 13.8 8.5 22.9 14.4 15.1 27.5 19.9 26.8 14.4 9.0 25.9 35.1 56.3 28.8 37.6 19.6 30.3 12.2 41.9 43.2 36.4 38.5 35.0 42.3 32.1 32.0 35.2 34.0 26.7 25.3 32.0 54.5 26.5 37.7 24.1 33.5 71.0 39.9 44.1 33.9 48.2 41.6 47.4 41.3 28.2 48.0 31.9 SERP1 "FLJ43424, RAMP4" ENSG00000120742 "Stress associated endoplasmic reticulum protein 1" Q9Y6X1 3 150541994-150603228 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA038970: " "unprognostic (8.81e-3)" "unprognostic (2.35e-3)" "unprognostic (1.91e-1)" "unprognostic (7.29e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-2)" "unprognostic (2.35e-3)" "unprognostic (6.16e-2)" "unprognostic (1.77e-3)" "prognostic unfavourable (1.03e-5)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (2.55e-2)" "unprognostic (2.75e-2)" "unprognostic (4.75e-2)" "unprognostic (1.78e-1)" 24.5 34.2 23.1 22.4 22.6 25.4 38.0 12.5 18.4 38.6 26.7 15.6 59.9 21.4 20.2 56.7 29.6 28.1 25.1 15.1 17.4 16.5 27.7 93.6 38.1 47.8 17.5 15.6 31.5 137.6 21.1 33.0 33.2 14.7 32.9 23.8 15.6 103.1 58.9 9.7 18.1 33.5 15.6 18.9 42.9 38.4 17.8 16.0 38.4 51.3 17.3 33.6 31.2 29.8 49.6 67.9 76.4 89.1 36.8 68.2 90.5 32.4 7.0 10.6 8.0 15.7 18.4 24.5 23.2 15.0 12.7 15.0 18.1 14.3 26.2 44.9 16.7 15.9 17.2 12.0 16.9 16.1 14.9 27.8 6.0 18.3 30.7 25.0 18.7 10.9 21.5 7.3 36.9 14.8 13.5 37.1 10.8 14.0 21.1 21.8 20.0 18.1 27.6 8.1 81.5 15.3 10.4 18.4 15.7 8.9 19.7 35.1 17.3 24.6 14.3 6.1 11.2 13.1 17.8 119.6 34.1 35.2 11.1 24.6 5.6 62.2 88.3 76.4 52.9 81.8 68.2 49.6 56.9 53.3 67.5 47.9 56.7 52.1 64.4 36.8 89.1 67.9 54.3 90.5 23.1 22.6 12.5 18.4 17.4 16.5 17.5 15.6 14.7 16.0 SERPINA12 "OL-64, Vaspin" ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 81.9" "Cell line enriched" "Detected in some" 6 "Hep G2: 6.9" "Cancer enhanced" "Detected in some" "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "cerebellum: 0.2" "Secreted in other tissues" 570000 "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SESN2 "DKFZp761M0212, HI95, SES2, SEST2" ENSG00000130766 "Sestrin 2" P58004 1 28259527-28282491 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 22.7;SK-MEL-30: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018191 Uncertain Approved Cytosol Cytosol "HPA018191: AB_1856750" "unprognostic (7.05e-2)" "unprognostic (4.95e-3)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "prognostic unfavourable (4.78e-4)" "unprognostic (8.97e-2)" "unprognostic (2.50e-3)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-1)" 9.2 7.7 7.0 6.8 6.7 32.0 7.6 6.1 11.1 6.1 9.6 3.5 4.6 14.3 7.2 4.0 15.2 6.2 7.6 4.3 4.5 6.1 12.5 18.4 7.7 4.1 8.4 4.5 22.4 10.4 7.5 5.4 9.3 7.6 5.2 8.3 6.9 14.5 4.6 5.8 4.9 12.6 6.2 10.9 5.8 7.2 9.2 4.3 4.8 7.0 4.2 9.7 7.3 14.9 1.9 2.8 6.2 2.7 3.9 9.6 2.5 2.6 1.4 3.5 5.7 5.6 4.4 18.8 5.0 4.6 3.0 3.6 2.0 1.9 2.9 2.1 2.2 2.6 4.0 3.5 2.1 2.6 3.7 1.2 2.0 3.3 18.4 4.4 6.7 14.0 22.7 8.2 19.7 3.4 6.9 14.2 2.8 1.5 1.6 1.2 2.7 2.9 2.5 0.9 6.5 2.0 4.4 1.2 1.3 1.4 1.1 27.3 3.1 6.3 1.9 1.5 4.8 3.5 3.0 18.5 4.6 4.6 3.7 4.5 3.5 0.0 2.3 1.9 9.6 1.9 4.7 1.9 3.4 4.6 2.4 1.4 2.1 4.3 6.2 3.9 2.7 2.8 3.9 2.5 7.0 6.7 6.1 11.1 4.5 6.1 8.4 4.5 7.6 4.3 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261958-41309497 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 105.4;BJ hTERT+ SV40 Large T+: 30.5;HBF TERT88: 43.2;hTCEpi: 39.4;NTERA-2: 31.5;RPTEC TERT1: 64.8;WM-115: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" 1600000 Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: " "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favourable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavourable (3.12e-4)" 20.1 3.4 4.6 2.4 7.5 0.3 73.2 10.8 5.6 58.4 6.1 15.2 8.0 3.0 35.6 19.3 9.7 25.9 15.5 43.9 7.8 2.5 30.6 1.5 1.8 0.9 4.5 6.7 12.5 1.5 0.6 0.7 9.9 24.1 12.8 7.8 19.3 73.2 27.1 1.9 20.8 5.4 21.4 2.8 5.0 11.0 11.1 13.7 0.0 3.3 18.4 5.1 10.9 41.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 11.6 0.3 10.6 0.6 2.2 20.0 105.4 30.5 29.1 0.0 2.6 0.0 0.1 0.1 0.1 1.6 8.0 43.2 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.1 1.8 39.4 3.0 3.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 31.5 0.0 0.0 2.4 0.0 64.8 0.0 0.6 2.8 0.8 0.0 6.1 0.0 0.3 0.2 0.0 3.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 7.5 10.8 5.6 7.8 2.5 4.5 6.7 24.1 13.7 SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178733-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 83.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 25.6;non-classical monocyte: 41.6" "Lineage enriched" "Detected in many" 6 "monocytes: 41.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved "HPA052352: " "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" "unprognostic (9.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (2.67e-3)" "unprognostic (1.29e-1)" "prognostic unfavourable (4.18e-5)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (5.22e-3)" 23.9 12.1 9.6 12.5 15.9 7.0 23.5 16.2 18.0 12.7 19.2 28.0 19.4 27.1 16.6 14.3 8.7 13.0 15.6 14.9 11.2 10.0 10.0 21.2 29.7 21.3 15.0 14.5 30.6 83.9 12.0 17.4 13.8 17.4 24.5 14.9 14.1 25.5 16.7 11.1 19.5 31.7 18.2 25.4 17.3 35.4 13.8 13.0 6.2 15.4 8.4 12.5 16.1 9.7 7.3 3.5 0.5 41.6 0.4 0.6 2.8 4.3 4.6 5.7 7.9 19.1 17.2 18.8 7.9 10.4 5.1 4.7 12.3 17.5 4.6 12.6 20.7 4.8 5.5 6.1 4.2 6.8 6.6 3.0 8.1 9.0 9.9 2.7 8.4 21.2 6.8 6.5 7.1 10.2 6.1 10.4 11.8 9.5 3.8 3.2 2.6 3.5 2.9 3.9 13.1 6.7 4.8 1.7 4.2 8.4 20.6 1.3 16.6 3.3 6.3 6.7 4.4 4.4 1.8 7.3 2.6 4.8 3.8 5.7 4.9 0.1 4.2 0.1 0.6 25.6 0.5 5.7 0.3 0.4 3.5 7.3 0.5 0.4 0.5 0.4 41.6 1.9 0.4 2.8 9.6 15.9 16.2 18.0 11.2 10.0 15.0 14.5 17.4 13.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016026 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA016026: AB_1857321" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favourable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favourable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.8 3.9 6.8 7.3 34.0 10.1 4.0 5.1 7.3 3.9 4.5 13.1 6.2 4.6 7.1 5.9 8.3 5.3 3.8 5.1 3.4 2.2 5.0 3.4 6.4 7.4 4.8 3.3 9.8 5.7 5.7 7.4 4.6 4.6 6.7 6.1 2.7 5.0 4.4 2.3 3.9 6.7 7.3 5.5 8.7 5.3 3.2 7.5 7.5 3.1 3.0 7.5 3.9 6.4 8.6 5.2 5.5 7.0 1.9 1.5 9.7 2.8 6.8 5.8 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 SIRT3 SIR2L3 ENSG00000142082 "Sirtuin 3" Q9NTG7 11 215458-236931 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026809, CAB037142" Approved "CAB037142: AB_1079982, HPA026809: AB_10601160" "unprognostic (1.76e-2)" "unprognostic (2.69e-1)" "unprognostic (2.04e-1)" "prognostic favourable (8.51e-5)" "unprognostic (1.52e-3)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (5.52e-2)" "unprognostic (8.64e-2)" "unprognostic (1.31e-1)" "prognostic favourable (4.45e-4)" "unprognostic (2.06e-1)" "prognostic favourable (4.85e-9)" "unprognostic (1.04e-1)" "unprognostic (5.53e-2)" "unprognostic (3.45e-1)" "unprognostic (3.75e-2)" 8.2 9.3 15.1 8.2 26.3 8.6 17.4 16.7 24.5 8.4 9.9 16.2 8.2 11.2 11.2 36.8 8.4 13.2 6.9 19.8 14.7 14.8 10.4 15.2 8.6 10.7 11.9 16.2 17.4 12.8 15.0 18.7 6.1 17.1 12.6 12.9 15.4 12.0 11.9 21.2 17.3 11.3 9.2 8.8 11.1 9.0 16.5 11.9 4.4 13.4 9.3 12.6 7.9 7.1 7.2 6.3 3.7 8.0 10.5 9.3 4.0 7.0 9.6 13.0 13.8 16.3 19.3 6.4 10.1 9.2 8.7 7.0 8.0 16.9 4.4 4.8 6.9 13.0 6.5 6.0 8.1 8.4 9.4 5.4 9.8 9.8 6.9 7.0 13.6 15.0 11.9 8.0 8.9 5.5 11.1 8.8 4.0 8.6 2.9 11.1 5.9 10.6 7.9 10.8 7.3 8.6 4.8 7.6 6.0 8.5 13.2 4.4 9.6 1.8 7.3 8.9 4.3 2.4 3.0 15.3 12.3 5.9 9.4 5.9 4.8 0.0 4.2 3.7 5.6 3.6 6.2 7.2 5.2 6.4 4.0 6.8 9.3 7.6 2.4 10.5 8.0 6.3 5.5 4.0 15.1 26.3 16.7 24.5 14.7 14.8 11.9 16.2 17.1 11.9 SIRT4 SIR2L4 ENSG00000089163 "Sirtuin 4" Q9Y6E7 12 120302316-120313249 "Cancer-related genes, Predicted intracellular proteins" "DNA damage" Transferase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 10.3" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029691, HPA029692" Enhanced "HPA029691: AB_10600118, HPA029692: AB_10611520" "unprognostic (2.62e-2)" "unprognostic (7.08e-2)" "unprognostic (4.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-2)" "unprognostic (1.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "prognostic favourable (1.75e-4)" "unprognostic (4.97e-2)" "unprognostic (2.11e-1)" "unprognostic (9.74e-3)" "unprognostic (2.31e-1)" 0.4 4.4 1.8 0.7 1.6 0.0 0.9 5.1 3.2 1.1 2.6 3.8 1.9 0.6 1.3 1.4 1.0 4.4 1.7 1.7 3.6 3.7 1.5 1.0 1.2 2.8 1.9 2.4 0.6 0.6 1.1 0.8 3.0 1.4 10.2 3.3 1.2 1.8 0.7 1.2 1.9 5.8 1.9 0.8 1.2 1.0 5.1 4.8 8.5 1.8 2.9 7.4 1.8 1.0 2.3 3.2 1.6 10.3 3.5 1.6 2.3 2.7 1.9 5.1 2.5 1.6 1.7 2.8 1.3 0.6 3.2 1.1 3.4 3.3 4.3 0.0 0.5 1.9 2.6 1.8 0.9 3.1 2.8 1.0 0.7 2.6 3.2 0.2 2.9 1.3 3.1 2.7 1.8 2.0 3.8 6.0 1.7 2.7 0.2 3.3 2.8 1.7 0.2 1.4 3.9 0.7 0.4 1.6 2.7 1.4 0.5 4.1 3.5 0.4 1.6 1.1 2.5 8.5 1.8 0.2 5.2 0.7 7.4 3.3 3.4 4.1 1.0 5.1 5.9 5.2 0.0 2.9 0.1 4.8 0.3 1.8 SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957013 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: " "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavourable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavourable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavourable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavourable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" 11.6 7.2 17.4 8.7 19.5 3.1 4.4 10.0 24.0 4.6 23.4 12.7 3.3 18.4 19.3 15.1 10.4 8.7 8.3 39.0 19.5 12.3 6.5 26.9 3.2 5.8 19.2 6.5 6.0 1.9 5.6 3.7 18.8 16.6 8.3 18.1 22.8 2.5 6.5 31.4 7.5 9.5 20.0 16.1 4.8 14.5 17.9 22.5 4.9 5.4 17.7 6.2 9.6 6.2 3.0 5.9 0.6 3.2 2.0 11.4 2.4 19.9 4.7 14.4 12.3 10.0 8.5 47.4 10.8 8.2 8.5 13.7 15.8 11.6 21.9 15.1 9.7 19.1 20.1 20.1 16.1 13.7 20.4 18.0 12.8 18.3 17.7 22.9 1.9 11.9 24.6 12.6 24.7 20.5 22.7 14.6 9.5 3.9 13.5 11.5 46.6 15.0 12.0 22.8 15.1 10.5 0.3 16.0 8.4 20.9 0.6 16.0 0.9 8.7 13.8 8.2 14.5 16.1 15.9 7.7 6.7 22.1 23.8 14.5 10.1 0.6 3.2 0.0 4.1 2.6 6.3 3.0 4.1 4.4 5.9 2.1 4.4 3.8 0.3 2.0 0.7 1.0 11.4 2.4 17.4 19.5 10.0 24.0 19.5 12.3 19.2 6.5 16.6 22.5 SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143241-185150382 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Transport" "Cardiomyopathy, Disease mutation, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 163.7;skeletal muscle: 92.5;tongue: 62.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.5;dendritic cells: 3.0;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria Mitochondria "HPA046835: , HPA071684: " "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favourable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favourable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" 3.0 4.2 6.9 2.0 10.8 1.4 3.1 19.4 14.4 2.6 6.6 3.7 2.9 2.8 3.0 3.4 6.7 3.7 3.5 163.7 7.4 7.3 8.3 4.3 3.0 2.0 6.3 6.1 3.6 3.0 4.6 4.6 2.2 12.8 6.2 3.4 7.9 4.4 8.5 92.5 2.3 4.1 5.5 4.5 2.1 5.3 3.1 2.3 0.0 4.6 62.4 3.4 4.4 2.1 3.5 3.0 0.4 0.0 0.7 4.1 1.5 0.7 3.2 2.7 5.4 2.9 0.3 4.9 2.7 0.9 3.3 3.3 7.0 1.8 2.3 1.9 3.2 2.6 10.3 2.8 2.1 4.0 8.8 1.6 4.9 8.2 6.0 1.4 1.6 2.2 7.0 5.0 1.4 2.4 3.8 1.8 2.0 5.1 1.6 3.1 4.3 7.0 2.6 1.4 3.3 7.4 5.0 8.7 6.6 3.2 1.4 12.4 2.5 1.2 1.8 0.2 1.5 1.6 3.4 7.8 3.5 3.0 2.4 0.3 3.0 0.0 0.0 0.0 4.1 0.0 3.1 3.5 1.4 3.5 0.1 2.2 1.2 3.0 0.4 0.7 0.0 3.0 1.2 1.5 6.9 10.8 19.4 14.1 7.4 7.3 6.3 6.1 12.8 2.3 SLC25A5 "2F1, ANT2, T2, T3" ENSG00000005022 "Solute carrier family 25 member 5" P05141 X 119468400-119471319 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Chromosome partition, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria 7800000 Mitochondria "HPA046835: , HPA071684: " "unprognostic (1.25e-2)" "prognostic favourable (7.35e-4)" "prognostic favourable (7.47e-4)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (1.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "prognostic favourable (8.06e-6)" "unprognostic (1.41e-1)" "unprognostic (2.65e-1)" "unprognostic (4.36e-2)" "unprognostic (3.03e-1)" 26.0 28.9 26.8 32.2 29.5 36.5 36.6 21.8 39.0 23.0 74.1 16.3 26.0 120.7 22.5 18.3 64.1 17.5 39.5 31.4 22.5 18.8 80.7 71.0 38.3 53.8 27.2 23.8 18.1 128.2 22.5 14.6 30.7 24.2 18.9 84.9 20.1 58.3 21.5 16.6 42.1 157.5 33.6 20.5 34.3 68.2 16.8 17.1 87.0 31.1 59.9 47.0 30.8 33.8 51.6 97.8 18.5 113.2 33.4 48.0 84.9 81.9 78.8 30.9 53.1 19.8 29.2 57.4 30.6 33.4 64.7 58.0 65.5 52.0 104.1 41.3 29.4 57.7 75.7 64.0 59.2 27.5 73.0 35.1 47.6 46.6 25.1 95.2 58.0 31.7 72.0 66.6 42.5 67.1 28.1 43.1 35.3 182.5 84.2 96.7 65.0 127.1 46.3 39.1 80.8 49.3 66.0 37.4 35.4 52.7 80.2 62.1 33.1 48.2 27.9 30.6 44.3 68.2 109.9 50.6 62.9 83.3 33.9 97.4 49.5 10.1 68.1 18.5 20.7 113.2 23.9 51.6 30.1 26.9 97.8 39.7 30.1 28.3 11.3 33.4 84.9 53.9 48.0 84.9 26.8 29.5 21.8 39.0 22.5 18.8 27.2 23.8 24.2 17.1 SLC25A6 "ANT3, ANT3Y, MGC17525" ENSG00000169100 "Solute carrier family 25 member 6" P12236 X 1386152-1392724 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 85.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria 7200000 Mitochondria "HPA046835: , HPA071684: " "unprognostic (1.13e-1)" "unprognostic (1.65e-2)" "unprognostic (4.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-3)" "unprognostic (1.34e-1)" "unprognostic (8.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (4.57e-3)" 18.5 19.7 12.1 12.2 14.0 23.7 14.4 8.2 12.2 9.8 16.5 28.9 14.3 4.8 16.4 10.4 7.0 9.4 10.3 8.2 18.4 5.4 11.1 14.4 9.4 25.6 38.7 10.1 14.0 8.6 12.4 8.8 45.0 12.5 6.1 14.9 23.3 7.7 5.8 15.4 19.2 2.4 16.3 9.5 14.2 11.2 62.2 85.7 3.7 69.0 30.1 43.6 71.2 22.0 48.3 34.3 35.0 23.8 46.4 37.1 33.8 32.4 24.9 24.8 63.8 27.0 81.9 27.3 22.2 14.3 23.0 40.3 7.9 20.5 73.1 44.8 33.1 72.8 55.8 32.2 54.7 76.5 74.3 19.5 28.7 37.0 31.2 19.3 24.4 46.9 59.6 61.7 43.5 65.0 30.1 28.4 63.5 30.4 55.4 56.0 88.0 22.8 69.4 96.1 38.5 66.4 42.2 25.5 14.3 49.7 33.6 50.1 8.0 55.3 3.8 31.1 13.8 2.4 58.1 3.7 29.4 69.0 43.6 62.2 40.4 34.8 85.7 47.5 38.1 37.2 3.0 30.1 67.9 41.0 38.7 71.2 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 17.5;SK-MEL-30: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: " "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favourable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 14.5 14.3 13.1 5.2 13.9 2.0 9.3 20.1 19.3 11.8 6.4 44.1 10.1 4.6 8.9 6.4 5.9 14.7 11.0 18.3 12.9 10.0 5.2 5.2 8.5 6.7 22.0 17.2 23.2 14.5 26.1 9.8 7.5 16.1 11.0 2.6 9.6 26.7 13.0 24.2 13.7 3.7 5.5 13.4 7.1 10.9 9.6 19.3 1.3 9.9 4.7 5.3 6.9 8.8 0.5 7.4 0.3 9.9 1.7 3.2 4.6 3.6 1.8 2.5 6.0 17.5 9.8 2.1 2.6 6.9 3.0 4.5 0.2 11.2 1.2 5.0 4.3 4.4 0.2 4.1 0.7 1.4 0.8 0.7 0.2 1.3 3.4 0.3 4.0 9.0 2.9 3.0 1.2 2.0 0.4 0.7 1.9 1.5 1.9 2.9 0.7 3.2 2.8 2.0 0.8 1.9 1.1 0.8 1.8 1.8 0.9 28.9 3.2 0.9 1.2 5.9 3.8 4.6 1.8 2.5 1.8 0.4 6.0 3.1 4.1 0.0 9.9 0.3 1.7 4.7 3.2 0.5 1.2 2.1 7.2 0.3 1.6 2.1 0.0 1.7 1.8 7.4 0.7 4.6 13.1 13.9 20.1 19.3 12.9 10.0 22.0 17.2 16.1 19.3 SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340646-128361470 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 56.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Supported Vesicles Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favourable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" 7.7 7.1 9.9 7.0 13.6 2.5 4.9 9.4 26.5 6.5 25.7 15.8 5.2 54.0 6.6 5.6 26.1 4.4 9.8 7.7 11.6 15.9 17.7 20.8 5.8 5.0 14.8 9.6 5.6 11.3 9.8 5.4 5.8 21.9 5.7 8.3 6.7 7.5 7.3 6.7 24.3 56.1 8.1 11.6 5.1 8.6 13.2 7.9 6.8 12.7 15.2 14.9 8.5 9.5 3.7 7.2 2.6 6.2 1.9 8.1 3.3 10.2 20.1 10.3 13.2 15.7 4.8 11.8 8.7 5.5 10.0 7.3 14.4 10.0 9.6 7.0 9.3 35.2 12.4 10.0 3.1 9.6 19.0 5.7 17.7 12.4 8.4 10.5 9.2 6.3 13.7 10.4 8.3 11.4 13.5 6.7 9.2 25.2 12.4 10.0 4.6 32.0 15.2 10.1 17.8 17.2 15.4 17.9 9.8 14.5 26.7 9.5 13.3 4.0 16.7 12.1 11.8 13.1 10.7 6.0 8.5 3.1 12.3 6.3 13.6 0.0 4.1 2.6 8.1 5.6 6.1 3.7 5.2 6.4 7.2 1.7 4.1 4.3 1.6 1.9 6.2 6.4 3.6 3.3 9.9 13.6 9.4 26.5 11.6 15.9 14.8 9.6 21.9 7.9 SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 45.7;Hep G2: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 33.8" "Lineage enriched" "Detected in all" 5 "dendritic cells: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favourable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favourable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favourable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" 10.9 24.5 11.4 13.3 11.3 3.5 10.4 15.0 15.2 9.0 19.8 11.7 37.0 17.7 9.5 17.4 8.7 6.0 9.4 9.8 10.4 9.3 8.7 25.7 8.1 7.3 12.5 10.2 6.7 12.1 5.7 5.5 13.2 8.7 18.5 6.5 12.5 9.4 28.3 22.6 11.6 17.0 44.1 10.3 11.3 13.1 30.6 9.3 1.2 9.1 6.9 4.3 42.4 9.1 2.4 33.8 6.9 5.6 1.2 6.3 2.0 1.7 7.0 3.2 7.0 0.0 0.0 10.0 2.7 1.8 4.4 2.6 45.7 1.7 2.7 6.2 1.4 9.5 3.8 4.4 1.1 2.6 6.1 0.4 5.5 26.9 4.1 0.0 3.0 0.1 4.1 0.4 1.8 3.4 2.9 6.2 1.7 12.9 0.0 0.0 5.1 11.1 1.0 4.4 7.6 4.1 18.9 5.3 3.6 6.6 11.3 2.4 7.3 1.6 2.9 0.0 4.6 0.3 6.1 19.1 17.8 4.1 3.0 0.0 3.3 0.0 3.0 6.9 4.9 5.6 3.5 2.3 1.6 3.3 4.6 2.4 0.3 1.2 0.2 1.2 5.1 33.8 6.3 2.0 11.4 11.3 15.0 15.2 10.4 9.3 12.5 10.2 8.7 9.3 SLC8B1 "FLJ22233, NCKX6, NCLX, SLC24A6" ENSG00000089060 "Solute carrier family 8 member B1" Q6J4K2 12 113298759-113359493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040668 Approved "HPA040668: AB_10793861" "prognostic favourable (9.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.27e-1)" "unprognostic (4.30e-1)" "unprognostic (1.93e-2)" "unprognostic (2.80e-3)" "unprognostic (1.90e-1)" "unprognostic (6.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-2)" "unprognostic (2.60e-1)" "unprognostic (5.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.54e-3)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "prognostic favourable (5.02e-4)" 12.6 43.9 7.2 15.0 9.5 12.0 11.0 5.5 7.8 11.8 11.1 9.0 7.9 7.7 9.0 10.9 9.3 7.2 10.4 9.2 6.5 3.7 10.6 18.6 12.2 26.2 8.2 4.5 35.1 13.2 5.5 9.3 15.5 7.0 10.0 7.5 6.2 10.4 9.6 7.1 11.2 14.1 9.3 9.6 20.8 7.6 13.9 8.0 29.5 8.2 8.1 14.4 8.4 10.8 3.1 11.4 18.5 14.7 3.3 18.8 8.4 12.2 2.7 1.6 3.6 8.4 5.8 5.3 3.9 12.4 5.6 5.5 2.8 10.2 3.3 9.2 5.8 10.0 5.2 2.9 2.7 7.7 1.5 6.3 6.0 3.0 13.9 16.4 14.2 5.9 8.9 6.4 2.8 12.8 13.2 1.7 3.1 2.8 5.0 13.3 2.9 7.0 1.9 2.2 3.8 6.0 17.5 0.1 2.8 11.6 23.4 2.8 3.7 6.5 26.5 3.9 4.6 11.1 2.5 2.1 5.0 2.4 4.8 9.3 3.0 2.4 9.6 18.5 5.0 14.7 6.4 2.2 9.2 4.9 11.4 3.1 18.8 8.6 6.3 3.3 14.1 8.5 10.9 8.4 7.2 9.5 5.5 7.8 6.5 3.7 8.2 4.5 7.0 8.0 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098815-27166981 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 60.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavourable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavourable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 7.1 11.3 7.5 9.9 10.1 7.3 8.4 11.7 18.9 8.7 14.0 5.0 26.9 20.7 10.6 6.8 10.3 7.1 24.4 13.4 4.6 5.3 7.3 2.4 11.2 5.8 5.0 6.7 6.9 6.4 13.4 8.0 42.5 14.8 8.5 10.2 10.1 60.7 55.4 3.8 9.2 24.7 8.1 3.9 10.5 45.6 8.3 4.9 6.0 8.0 6.5 9.0 18.8 8.4 0.9 0.6 5.5 1.5 0.4 4.2 1.8 13.5 4.7 4.4 4.5 10.1 7.3 27.3 11.1 17.1 9.8 10.7 5.6 8.8 6.1 9.6 14.6 17.0 4.3 27.7 6.1 7.3 4.0 9.3 3.0 2.4 30.7 5.5 7.1 9.1 13.4 16.5 23.0 16.2 2.6 6.0 14.4 8.1 2.8 2.9 6.2 9.7 5.0 3.9 2.8 5.1 20.5 5.1 1.6 9.4 12.8 5.6 5.9 3.4 17.4 10.4 4.2 9.7 6.1 5.4 3.4 1.8 11.2 6.1 6.0 0.1 1.5 1.5 1.9 0.9 4.2 0.2 2.2 2.0 0.6 0.9 1.4 1.7 5.5 0.4 1.5 0.1 0.8 1.8 7.5 10.1 11.7 18.9 4.6 5.3 5.0 6.7 14.8 4.9 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 45.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.6;NK-cells: 12.2;T-cells: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "HPA047008: " "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.3 7.9 8.8 6.3 13.3 5.3 5.5 16.5 24.5 5.6 5.0 5.2 0.4 2.0 8.5 4.2 4.7 5.9 9.8 5.5 8.9 12.5 1.9 45.6 3.3 7.2 10.3 13.4 8.0 2.4 1.2 8.8 5.2 20.8 5.6 3.9 8.3 2.1 6.7 4.5 3.7 3.0 9.8 9.8 4.6 5.7 4.8 4.7 2.5 2.6 1.8 6.9 5.5 8.5 5.6 1.7 0.0 0.1 12.2 6.3 1.8 2.6 1.3 3.1 6.4 15.5 13.0 0.0 11.9 4.7 2.0 1.8 1.3 1.7 16.8 2.1 13.8 0.8 7.0 5.0 2.8 14.7 4.9 16.8 4.2 12.1 8.3 11.7 5.3 11.4 6.7 4.2 14.5 8.5 5.6 12.3 6.2 1.0 9.4 7.2 2.3 3.8 0.0 3.4 7.3 5.7 1.0 10.7 9.7 5.4 1.4 3.5 1.4 7.8 10.5 4.4 2.7 6.9 4.1 10.5 7.6 12.2 5.3 10.3 1.7 0.0 0.1 0.0 5.1 0.0 6.3 5.6 5.6 4.5 0.9 3.6 3.4 4.2 0.0 12.2 0.1 1.7 2.4 1.8 8.8 13.3 16.5 21.2 8.9 12.5 10.3 13.4 20.8 4.7 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: " "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 38.5 39.2 29.0 26.2 25.9 19.6 31.4 19.5 28.9 28.8 34.2 29.4 28.9 21.5 26.6 26.3 33.5 28.8 25.7 31.1 26.1 27.1 26.4 20.9 28.3 23.8 30.9 24.3 36.6 28.1 25.7 24.4 34.8 28.6 27.8 29.8 31.7 29.7 28.7 33.9 28.0 26.4 34.6 35.4 34.1 26.3 29.2 26.2 60.7 46.1 23.6 31.5 35.1 35.7 12.0 21.8 28.9 24.7 24.5 25.9 19.7 22.4 32.2 19.7 19.0 31.5 38.5 22.5 24.5 29.4 25.6 29.9 12.3 21.5 34.9 17.6 31.0 24.8 22.1 27.3 34.3 37.9 11.3 29.6 48.7 19.9 36.7 41.1 30.3 28.4 35.3 21.9 50.7 28.2 13.7 29.3 31.4 14.6 28.2 19.8 9.6 7.7 20.6 28.7 23.8 57.4 38.7 18.2 21.4 29.5 20.2 24.0 15.3 27.4 31.5 38.0 21.9 10.3 17.8 28.7 27.5 30.4 26.3 28.1 27.7 28.9 22.6 25.0 16.9 24.7 21.2 12.0 23.1 20.9 21.8 9.4 25.8 19.8 22.7 24.5 20.8 15.5 25.9 19.7 29.0 25.9 19.5 28.9 26.1 27.1 30.9 24.3 28.6 26.2 SMARCC1 "BAF155, CRACC1, Rsc8, SRG3" ENSG00000173473 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1" Q92922 3 47585272-47782106 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011576, CAB016336, HPA024352, HPA026853" Supported Enhanced Nucleoplasm Nucleoplasm "CAB011576: AB_2191988, CAB016336: AB_671095, HPA024352: AB_1857274, HPA026853: AB_10603030" "unprognostic (3.47e-1)" "unprognostic (1.65e-1)" "prognostic favourable (3.34e-4)" "unprognostic (2.54e-1)" "unprognostic (1.83e-2)" "unprognostic (3.70e-2)" "prognostic unfavourable (3.37e-4)" "unprognostic (1.33e-2)" "unprognostic (4.28e-3)" "unprognostic (6.92e-2)" "unprognostic (5.53e-2)" "unprognostic (2.78e-2)" "unprognostic (1.66e-2)" "unprognostic (7.99e-2)" "unprognostic (3.84e-1)" "unprognostic (2.31e-2)" "unprognostic (2.45e-1)" 16.5 9.3 14.5 22.6 18.9 16.7 21.8 16.5 17.2 19.3 22.4 19.6 13.1 13.3 20.0 15.2 21.8 12.5 16.4 10.3 13.9 11.3 18.7 15.6 13.6 18.6 18.1 11.3 18.7 25.6 16.4 15.1 28.0 11.7 22.1 20.8 14.5 18.9 16.9 19.8 24.3 17.8 32.6 16.1 18.7 16.6 18.7 18.3 45.0 21.1 12.8 27.7 24.9 27.0 8.2 4.7 4.3 5.4 4.0 8.1 3.9 14.3 7.6 32.0 24.8 7.2 12.3 21.6 11.5 10.8 14.9 15.3 13.6 15.3 33.6 9.3 14.4 12.4 30.1 17.8 21.9 16.0 17.9 32.9 13.1 18.5 10.8 30.1 15.2 10.3 15.8 16.8 18.7 17.4 27.6 11.4 16.0 10.7 39.1 15.7 42.2 11.7 17.6 18.6 29.5 16.0 18.9 14.3 28.8 17.8 17.5 12.7 15.2 28.1 13.9 10.0 14.2 11.3 18.7 14.0 17.8 40.1 7.3 28.5 14.0 4.0 3.5 3.4 6.2 5.4 5.6 8.2 6.7 8.1 4.4 6.3 6.4 7.5 4.3 4.0 3.8 4.7 6.3 3.9 14.5 18.9 16.5 17.2 13.9 11.3 18.1 11.3 11.7 18.3 SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10218830-10307418 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "brain: 356.9" "Group enriched" "Detected in some" 4 "Karpas-707: 10.8;SCLC-21H: 35.7;SH-SY5Y: 21.3;U-87 MG: 25.7" "Group enriched" "Detected in many" 6 "glioma: 28.9;pancreatic cancer: 6.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Vesicles "CAB000360: AB_2286342, HPA001830: AB_1080039, HPA071013: " "unprognostic (1.64e-3)" "unprognostic (7.26e-3)" "unprognostic (4.36e-2)" "unprognostic (2.49e-7)" "unprognostic (6.86e-3)" "unprognostic (5.87e-3)" "unprognostic (1.15e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (5.82e-3)" "unprognostic (4.80e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-3)" "unprognostic (2.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.02e-2)" 2.2 16.4 81.0 3.3 60.0 2.1 3.4 202.9 356.9 2.2 2.8 3.4 3.7 3.2 4.6 6.4 2.2 4.0 2.8 2.4 86.5 37.1 2.5 2.3 2.6 2.2 46.7 65.2 3.7 4.1 2.1 5.5 2.3 97.7 3.1 2.8 4.0 2.2 11.9 2.1 2.2 3.3 4.7 13.9 2.1 4.3 3.2 7.4 0.0 2.3 0.0 2.2 2.6 0.1 0.0 1.6 0.7 0.0 0.0 0.6 0.3 0.0 2.1 1.7 0.0 0.2 0.0 0.0 0.9 0.0 2.2 0.6 0.0 0.0 0.0 1.9 0.0 0.4 0.2 0.0 4.4 0.2 0.1 0.0 2.9 0.3 1.6 0.0 0.2 2.0 0.0 1.8 0.0 0.0 0.0 10.8 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 35.7 21.3 0.3 0.0 0.0 0.0 2.9 0.0 2.3 3.1 0.0 1.0 0.0 5.5 0.0 25.7 0.0 2.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.6 0.3 81.0 60.0 202.9 163.5 86.5 37.1 46.7 65.2 97.7 7.4 SNX1 "HsT17379, MGC8664, SNX1A, Vps5" ENSG00000028528 "Sorting nexin 1" Q13596 15 64094123-64146090 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047373, HPA052761" Approved Enhanced Endosomes,Lysosomes "Endosomes, Lysosomes" "HPA047373: AB_2680018, HPA052761: AB_2681939" "unprognostic (3.99e-2)" "unprognostic (8.65e-3)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (7.13e-2)" "unprognostic (2.73e-1)" "unprognostic (7.15e-2)" "unprognostic (6.49e-3)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.47e-2)" "unprognostic (3.26e-1)" "prognostic favourable (9.88e-6)" "unprognostic (2.27e-1)" "unprognostic (3.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.95e-1)" 30.6 47.3 22.4 27.4 31.2 16.8 36.3 17.7 25.3 32.4 30.3 46.9 44.7 26.0 30.8 39.2 38.7 21.2 23.5 30.9 24.8 20.1 30.6 38.6 33.7 31.3 40.1 23.5 25.0 31.2 43.0 22.2 31.1 30.3 31.0 27.1 22.5 30.8 48.4 40.9 29.1 26.3 30.4 54.1 37.5 30.2 17.7 35.9 32.9 80.8 18.5 35.9 32.3 31.7 34.5 42.3 51.9 50.6 30.7 30.6 43.9 19.0 25.4 22.0 18.7 39.0 29.2 7.1 26.3 31.1 28.1 33.2 17.2 34.7 22.9 27.1 27.6 29.9 34.8 31.5 23.5 37.0 15.4 26.3 29.9 24.7 21.3 26.5 30.1 32.9 20.3 21.9 17.1 28.9 20.8 9.0 29.0 28.4 28.2 22.5 14.9 15.0 25.6 20.3 32.2 43.3 45.9 17.8 17.0 23.4 18.0 22.8 25.8 24.6 28.7 24.5 33.1 15.6 15.1 23.9 60.4 32.4 19.6 36.4 25.3 41.5 50.6 51.9 29.7 47.2 25.0 32.0 25.4 28.9 42.3 34.5 24.7 24.0 38.1 30.7 43.5 28.4 30.6 43.9 22.4 31.2 17.7 25.3 24.8 20.1 40.1 23.5 30.3 35.9 SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122774996-122830108 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037400 Approved Supported Endosomes,Lysosomes 39000000 "Endosomes, Lysosomes" "HPA037400: AB_10670381" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavourable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favourable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" 32.1 28.0 27.7 36.0 27.7 22.1 52.1 30.4 24.7 22.0 24.1 14.1 34.0 20.4 24.7 36.6 25.3 24.9 22.0 33.3 27.2 17.4 38.5 30.1 39.5 58.9 27.2 23.2 33.1 26.2 24.7 29.8 34.7 26.0 23.3 24.5 12.4 27.7 29.7 20.9 23.4 27.4 35.8 27.7 45.8 27.0 14.5 28.1 16.0 40.4 21.2 34.6 30.3 30.4 84.6 34.5 30.5 43.5 9.6 16.5 32.1 16.3 13.1 17.3 13.5 39.2 23.9 73.4 13.3 20.7 15.6 22.8 22.9 23.8 21.1 32.9 15.2 5.6 36.3 24.2 23.2 20.8 21.7 21.4 13.0 15.6 26.4 9.3 16.0 22.4 18.6 16.3 23.5 17.1 10.9 15.6 16.7 14.8 7.7 12.5 10.8 15.5 33.3 17.3 23.7 23.3 26.7 13.9 10.5 15.5 18.0 21.5 22.7 22.5 19.3 13.9 12.5 19.9 15.1 11.7 14.5 23.0 18.4 34.3 16.6 30.5 43.3 26.7 8.7 43.5 10.0 84.6 11.9 10.4 34.5 84.4 11.8 9.9 15.2 9.6 42.7 10.2 16.5 32.1 27.7 27.7 30.4 24.7 27.2 17.4 27.2 23.2 26.0 28.1 SNX6 ENSG00000129515 "Sorting nexin 6" Q9UNH7 14 34561094-34630183 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049374 Approved Supported Endosomes,Lysosomes "Endosomes, Lysosomes" "HPA049374: " "unprognostic (1.89e-1)" "unprognostic (6.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.06e-2)" "unprognostic (1.12e-1)" "unprognostic (2.36e-3)" "prognostic unfavourable (1.25e-4)" "unprognostic (1.23e-1)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (4.68e-4)" "unprognostic (1.91e-1)" "unprognostic (3.48e-2)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" 35.7 27.0 26.7 23.0 23.2 16.3 29.4 19.0 21.5 20.8 28.1 30.7 17.7 37.0 37.9 18.0 24.9 16.3 21.6 19.0 28.3 22.0 30.4 18.6 17.6 33.5 33.7 18.1 20.7 15.5 61.1 19.1 46.2 26.7 22.3 24.3 14.7 20.1 18.6 20.3 18.3 38.4 23.2 50.9 33.6 20.8 23.1 23.3 28.5 21.5 19.6 21.9 28.5 22.5 30.5 29.4 56.0 43.1 29.8 43.9 45.2 31.7 18.0 21.0 13.6 32.7 67.4 29.5 31.4 34.8 32.4 28.4 17.3 39.7 20.6 26.3 41.2 22.5 22.2 23.2 56.7 25.2 8.9 12.4 11.0 31.6 28.1 21.8 15.5 43.3 25.6 22.1 32.2 44.0 13.3 17.1 43.3 18.3 19.6 10.7 11.4 21.6 21.0 24.3 20.8 41.3 24.3 16.5 17.8 25.3 22.0 26.3 28.4 14.2 43.2 23.3 16.6 22.5 20.1 15.8 25.7 23.4 12.7 12.0 25.9 26.7 32.8 39.5 32.3 43.1 41.7 30.5 43.9 37.4 29.4 27.0 33.6 36.0 56.0 29.8 39.7 19.3 42.7 45.2 26.7 23.2 19.0 21.5 28.3 22.0 33.7 18.1 26.7 23.3 SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 48.9;HSkMC: 24.9;U-266/70: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 6 "granulocytes: 11.6;T-cells: 4.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB012220: AB_443287, HPA068569: " "prognostic favourable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "unprognostic (4.41e-3)" "unprognostic (2.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (9.61e-3)" "unprognostic (1.84e-1)" "unprognostic (2.00e-2)" "prognostic unfavourable (9.34e-9)" "unprognostic (1.08e-2)" "unprognostic (8.80e-2)" "unprognostic (7.59e-3)" "unprognostic (8.40e-2)" 94.9 16.8 6.3 42.5 21.4 33.9 25.7 3.0 12.8 27.6 26.6 5.6 1.9 6.2 13.9 9.2 22.7 88.0 59.6 23.5 11.4 5.1 13.5 30.4 52.1 30.2 13.9 0.1 31.2 14.5 13.9 13.4 23.5 38.0 20.8 9.2 10.3 9.2 6.7 26.0 12.1 15.6 39.0 29.6 36.7 32.2 12.1 8.7 5.6 14.2 40.9 10.3 38.1 41.1 0.0 1.3 11.6 1.3 0.4 4.3 0.6 2.0 3.3 2.4 1.2 0.9 15.2 6.3 10.2 9.3 10.7 4.5 2.1 1.4 0.0 2.2 2.4 0.6 0.5 1.0 4.2 48.9 0.3 1.8 7.2 0.4 4.9 0.0 0.9 24.9 0.8 8.3 3.1 4.6 5.4 19.2 4.9 1.0 1.0 0.3 1.7 4.2 0.0 12.2 0.3 17.0 2.0 0.1 1.5 3.1 0.8 0.4 0.9 0.4 2.7 21.1 6.0 7.3 5.9 25.3 14.2 0.0 17.3 0.2 1.3 0.0 1.3 0.3 1.0 0.1 2.6 0.0 2.8 1.2 1.3 0.0 4.3 0.8 11.6 0.4 0.0 1.2 1.6 0.6 6.3 21.4 3.0 12.8 11.4 5.1 13.9 0.1 38.0 8.7 SOCS7 "NAP4, NCKAP4" ENSG00000274211 "Suppressor of cytokine signaling 7" O14512 17 38352228-38405593 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9;testis: 19.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004475 Approved Approved Cytosol Cytosol "HPA004475: " "prognostic unfavourable (7.49e-4)" "unprognostic (7.93e-2)" "unprognostic (2.01e-1)" "prognostic unfavourable (7.87e-4)" "unprognostic (7.93e-2)" "unprognostic (1.33e-1)" "unprognostic (1.43e-3)" "unprognostic (1.23e-1)" "unprognostic (1.77e-1)" "unprognostic (4.12e-3)" "unprognostic (1.97e-3)" "unprognostic (6.62e-2)" "unprognostic (4.91e-3)" "unprognostic (1.55e-2)" "unprognostic (1.53e-1)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" 2.4 1.9 6.1 2.5 6.7 2.1 3.2 22.9 7.8 2.6 2.3 3.5 3.3 2.2 3.6 4.2 3.5 3.2 2.3 2.7 5.1 2.4 0.9 2.6 1.8 3.3 5.1 5.1 9.1 5.1 0.9 2.2 2.9 3.1 2.7 2.9 3.6 3.2 6.0 5.2 2.1 3.6 1.4 1.7 1.4 19.7 4.3 4.7 5.2 1.8 2.8 2.4 2.4 0.8 1.0 0.2 0.9 0.7 2.6 0.3 8.7 9.9 11.2 8.6 6.3 5.3 9.2 3.8 3.3 4.7 3.8 7.7 2.7 6.0 5.9 6.1 5.9 9.5 2.7 6.0 11.2 8.5 6.4 11.2 8.0 2.1 14.0 11.0 3.3 11.1 4.9 6.8 4.0 5.2 4.1 5.8 4.8 12.0 9.2 3.6 1.5 12.0 18.7 5.5 3.1 10.8 19.7 10.7 9.5 6.2 6.8 11.5 7.9 3.9 4.7 4.2 8.5 11.8 14.5 10.0 8.9 6.4 7.1 9.5 0.2 0.9 0.1 2.1 0.5 2.6 0.8 0.7 0.3 0.4 0.7 0.4 0.6 0.2 0.7 0.5 1.0 1.1 0.3 SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777442-36863686 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 55.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" "Nucleoli, Cytosol" "HPA043992: " "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavourable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" 6.2 11.4 10.8 4.5 10.6 1.4 6.0 55.5 12.5 11.3 8.3 20.5 7.2 2.5 8.8 5.3 7.2 9.4 9.9 6.7 9.9 7.5 4.7 1.3 6.1 3.0 12.7 8.9 12.6 3.7 11.5 4.4 7.9 8.7 10.7 3.9 6.7 4.4 12.3 2.9 11.0 4.6 14.1 7.9 5.3 5.3 14.8 14.7 0.9 16.0 4.7 4.1 8.0 10.5 1.0 2.1 1.4 0.7 0.7 0.2 0.2 7.4 10.2 12.4 13.3 7.2 6.6 3.2 6.6 7.1 9.3 5.6 4.1 1.2 3.3 2.4 11.5 10.1 9.9 6.1 9.8 0.5 1.9 5.3 9.5 5.4 3.8 1.2 5.2 3.7 7.5 8.9 6.4 6.1 3.7 0.7 10.2 7.2 3.7 2.8 3.1 7.9 8.9 11.5 1.2 5.5 2.2 14.8 9.2 13.6 15.0 4.3 19.1 8.0 9.2 23.5 4.6 11.5 14.3 1.4 0.3 3.3 10.0 1.6 14.8 1.4 0.7 0.2 0.1 0.4 0.2 1.0 0.1 0.1 0.4 1.0 0.2 0.2 1.4 0.7 0.3 2.1 0.1 0.2 10.8 10.6 55.5 12.0 9.9 7.5 12.7 8.9 8.7 14.7 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397951 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.1;epididymis: 75.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 9.0;non-classical monocyte: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favourable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 22.9 6.5 24.0 6.2 35.5 10.1 15.5 6.4 40.6 10.1 15.2 50.3 18.1 11.5 11.9 75.2 22.0 14.8 9.5 31.8 45.2 19.8 21.1 3.7 19.2 3.6 57.9 22.8 3.6 9.3 24.2 5.7 22.9 27.1 10.3 14.4 12.2 11.8 24.8 36.4 8.3 11.3 14.6 71.1 5.4 9.5 21.6 42.2 1.1 22.5 5.1 5.4 8.7 8.2 0.0 4.5 2.3 10.0 0.4 0.0 1.7 11.6 4.7 11.8 14.3 34.4 6.8 34.0 8.7 13.9 8.6 9.2 12.1 4.3 0.1 11.1 3.6 2.9 13.9 6.9 12.4 0.3 6.6 3.2 7.6 13.0 13.5 0.0 10.6 17.1 1.1 10.5 2.3 1.3 24.1 1.2 12.0 12.4 8.2 0.2 4.4 1.9 9.2 27.8 5.6 16.4 8.5 12.1 6.9 5.1 34.2 36.7 14.4 2.0 0.3 1.8 7.0 0.3 14.5 11.6 9.5 0.0 3.1 0.0 7.5 0.0 7.1 2.3 0.0 9.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.9 0.4 10.0 1.6 0.0 1.7 24.0 35.5 6.4 33.9 45.2 19.8 57.9 22.8 27.1 42.2 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981396-39124345 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 25.9 13.2 19.2 18.8 18.1 12.0 26.1 33.3 18.6 18.6 21.9 12.1 15.3 18.3 19.1 14.6 17.4 17.0 18.1 16.4 17.9 14.1 14.6 15.2 19.9 19.9 18.2 14.0 28.1 13.0 33.5 21.7 21.5 17.8 18.4 16.8 14.6 15.9 18.1 26.2 15.0 23.1 22.3 14.6 16.2 20.1 12.7 20.1 23.1 19.4 12.9 21.8 25.1 22.0 3.2 1.4 3.2 2.0 6.2 4.6 0.9 9.7 6.0 9.4 6.7 12.7 15.2 9.8 6.2 7.6 4.9 4.7 6.5 5.9 14.2 4.2 8.0 5.8 11.0 5.6 9.2 14.2 4.9 22.0 5.2 8.9 5.2 7.0 55.8 9.3 9.0 6.7 6.5 7.7 9.3 6.7 6.3 5.3 7.5 6.5 5.8 4.3 8.4 8.5 4.1 5.2 7.9 9.1 9.1 7.3 13.2 7.6 4.2 3.7 8.6 8.2 6.7 6.4 6.1 7.9 8.0 7.5 6.6 6.9 4.9 0.0 1.2 3.2 3.2 1.8 4.6 3.2 3.3 3.3 1.0 2.4 3.7 3.4 1.4 6.2 2.0 1.4 1.9 0.9 19.2 18.1 33.3 18.6 17.9 14.1 18.2 14.0 17.8 20.1 SOX4 ENSG00000124766 "SRY-box 4" Q06945 6 21592768-21598619 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 21.8" "Cell line enhanced" "Detected in many" "AN3-CA: 55.4;MOLT-4: 47.6;SH-SY5Y: 31.2" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.8" "Group enriched" "Detected in all" 4 "dendritic cells: 21.8;granulocytes: 12.8;monocytes: 10.0" "Region enriched" "Detected in many" 4 "olfactory region: 66.5" "Low region specificity" "Detected in all" HPA029901 Approved Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA029901: AB_10601592" "unprognostic (4.01e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-2)" "unprognostic (5.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.08e-2)" "prognostic unfavourable (2.57e-5)" "unprognostic (1.78e-1)" "unprognostic (8.01e-3)" "unprognostic (1.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.18e-1)" "unprognostic (8.73e-3)" "unprognostic (3.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.01e-1)" "unprognostic (9.27e-2)" 4.2 0.7 2.0 1.9 0.9 6.0 6.3 3.0 6.3 6.7 2.8 3.0 18.0 4.1 2.3 4.2 5.5 2.0 1.1 1.8 4.3 1.3 5.1 0.8 0.6 18.1 5.3 0.0 1.8 1.0 4.1 3.7 9.6 1.4 0.3 4.1 2.7 4.9 0.3 1.0 4.4 2.5 3.4 1.4 6.2 3.6 3.1 21.8 12.8 10.0 3.3 1.1 2.0 1.8 5.2 13.3 55.4 4.9 1.2 21.7 0.8 1.7 1.0 0.9 3.5 3.5 0.6 22.2 1.3 5.4 6.9 3.8 0.7 7.6 14.5 0.5 2.4 2.3 0.8 1.8 0.4 2.1 3.9 0.4 1.6 15.6 0.1 0.0 1.1 4.3 47.6 4.5 9.9 5.0 21.0 1.1 0.0 9.6 16.7 17.4 31.2 7.7 9.0 2.9 4.4 6.5 11.9 1.5 5.2 0.3 3.9 0.3 0.0 15.4 0.5 6.5 6.1 12.8 9.8 0.9 0.2 5.5 0.0 2.8 0.1 0.1 4.1 3.1 1.1 0.8 0.4 3.3 10.0 21.8 0.9 2.0 SP1 ENSG00000185591 "Sp1 transcription factor" P08047 12 53380176-53416446 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000330, HPA001853, HPA012292" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000330: AB_2171049, HPA001853: AB_1080069, HPA012292: AB_1857394" "unprognostic (1.12e-1)" "unprognostic (8.52e-3)" "unprognostic (6.11e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (4.64e-3)" "unprognostic (1.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "prognostic unfavourable (1.43e-4)" "unprognostic (6.38e-2)" "unprognostic (5.14e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (4.77e-2)" "unprognostic (2.12e-2)" 20.7 18.1 8.8 13.9 14.2 17.0 20.1 30.0 14.7 20.9 21.9 17.5 19.3 19.6 25.4 21.2 35.0 20.4 18.7 12.1 14.1 6.8 31.3 14.1 17.6 14.2 18.3 9.7 22.5 17.9 19.0 11.3 19.5 14.4 16.2 20.1 21.5 25.8 19.5 22.0 25.8 30.0 18.4 21.0 19.0 18.8 22.4 15.2 25.8 16.6 17.3 26.6 25.1 21.6 2.7 3.0 11.2 4.2 1.7 2.8 1.4 17.7 19.5 22.3 16.3 18.0 20.8 17.8 12.8 16.6 15.8 14.6 16.2 35.6 24.1 17.0 14.7 25.7 25.6 17.4 17.7 18.4 14.9 21.2 24.7 8.8 12.6 19.3 17.9 21.9 18.1 16.2 31.5 16.2 20.3 34.9 11.6 25.4 28.8 14.8 12.3 14.7 20.5 21.5 14.2 12.4 32.1 11.8 15.7 26.0 21.9 13.2 27.5 20.7 15.6 18.6 17.4 13.8 13.6 12.0 13.8 24.1 14.2 16.1 14.8 4.5 4.2 2.5 2.2 2.7 2.8 2.3 2.2 2.1 2.4 2.7 2.4 2.6 11.2 1.7 3.1 3.0 1.6 1.4 8.8 14.2 30.0 14.7 14.1 6.8 18.3 9.7 14.4 15.2 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633343-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved "HPA051402: " "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavourable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 2.4 3.3 7.7 2.9 8.2 3.2 14.8 9.2 11.8 5.6 5.2 5.3 0.7 5.7 3.1 4.6 24.2 2.9 4.0 1.9 9.3 7.5 6.4 42.4 3.0 3.5 6.2 5.5 4.1 4.3 3.0 1.9 2.1 13.4 2.6 3.6 2.4 5.0 2.1 2.2 17.5 10.4 2.6 3.1 2.9 3.9 2.7 2.9 3.3 2.4 15.3 12.1 2.6 10.1 1.9 3.7 7.0 3.3 1.3 1.3 1.3 5.5 5.5 7.3 6.2 7.0 6.9 3.4 5.4 4.1 5.3 3.3 5.5 4.9 6.7 8.9 7.8 9.0 5.9 3.6 5.7 4.1 2.5 2.1 13.7 3.3 3.2 3.0 1.8 5.0 10.2 3.8 3.0 2.6 3.6 6.2 6.8 6.5 1.4 3.4 4.6 4.4 4.6 5.6 2.0 7.1 5.2 13.8 6.3 16.4 7.3 5.0 3.0 0.8 5.4 8.1 4.0 13.1 6.7 3.3 4.4 2.4 6.7 3.5 7.4 7.0 3.3 1.4 1.0 2.4 0.7 1.7 1.0 1.3 3.7 1.9 0.9 1.0 2.0 1.3 2.6 1.8 1.1 1.3 7.7 8.2 9.2 11.8 9.3 7.5 6.2 5.5 13.4 2.9 SRI ENSG00000075142 Sorcin P30626 7 88205118-88226993 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 140.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019004, HPA073666" Enhanced Supported Nucleoplasm,Cytosol 1400000 "Nucleoplasm, Cytosol" "HPA019004: AB_2670006, HPA073666: AB_2686623" "unprognostic (1.86e-2)" "unprognostic (2.31e-3)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-3)" "unprognostic (1.24e-3)" "prognostic favourable (3.08e-4)" "unprognostic (9.87e-2)" "unprognostic (2.15e-1)" "prognostic unfavourable (9.03e-4)" "unprognostic (1.36e-1)" "unprognostic (2.10e-2)" "unprognostic (1.29e-2)" "unprognostic (9.87e-2)" "unprognostic (8.44e-2)" "unprognostic (3.14e-3)" 20.6 22.0 47.7 24.6 53.5 18.7 22.4 18.9 43.6 24.1 140.7 32.5 7.0 45.3 18.1 33.1 15.6 39.4 14.2 19.4 35.9 40.2 21.7 14.6 21.9 16.6 45.0 44.8 23.3 18.4 12.1 18.3 21.2 36.9 19.5 115.0 11.1 17.7 18.4 8.7 11.1 62.8 25.2 41.9 14.6 16.2 10.0 28.0 9.2 19.7 9.4 19.4 27.0 18.7 29.7 34.5 95.4 42.1 36.3 36.4 32.7 34.1 13.1 35.5 36.5 57.6 48.6 17.8 20.5 33.3 23.2 27.6 12.2 77.6 38.0 21.7 31.1 34.6 44.6 46.5 30.4 30.6 20.0 19.7 36.2 0.0 34.9 26.2 21.1 49.7 42.6 24.5 35.7 69.5 17.4 33.0 31.8 21.6 38.2 18.0 31.2 26.5 15.9 50.3 21.0 43.2 34.2 25.7 30.5 62.6 36.0 28.6 17.0 11.7 43.4 43.5 36.5 39.9 36.5 30.9 14.3 40.7 42.7 25.1 73.7 86.5 26.1 95.4 31.0 36.5 36.4 29.7 34.5 35.2 34.5 24.9 25.8 29.8 16.3 36.3 42.1 27.5 34.7 32.7 47.7 53.5 18.9 43.6 35.9 40.2 45.0 44.8 36.9 28.0 SRSF4 "SFRS4, SRP75" ENSG00000116350 "Serine and arginine rich splicing factor 4" Q08170 1 29147743-29181987 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050975 Supported Supported "Nuclear speckles" "Nuclear speckles" "HPA050975: " "unprognostic (3.26e-3)" "unprognostic (8.08e-2)" "unprognostic (1.29e-2)" "unprognostic (1.57e-3)" "unprognostic (1.37e-1)" "unprognostic (5.89e-2)" "unprognostic (1.89e-3)" "unprognostic (1.63e-1)" "prognostic unfavourable (3.27e-4)" "unprognostic (2.36e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (4.26e-4)" "prognostic unfavourable (4.30e-4)" "unprognostic (6.25e-3)" "unprognostic (2.80e-1)" "unprognostic (7.75e-3)" "unprognostic (1.60e-2)" 42.5 26.5 26.8 31.7 34.6 46.6 38.7 37.5 28.3 33.9 35.8 27.9 30.7 35.1 39.0 29.1 35.9 30.7 26.3 28.7 26.0 22.3 27.8 40.7 36.7 37.1 35.0 24.1 43.0 30.4 28.5 27.0 40.7 27.9 35.2 26.2 27.8 33.6 34.8 47.0 38.0 34.0 52.6 30.7 38.7 29.9 23.4 33.8 46.9 35.1 23.6 30.0 55.6 70.2 23.8 25.6 44.8 26.1 20.0 35.0 20.7 31.0 18.6 34.9 12.7 25.5 19.4 21.8 26.2 19.3 31.0 26.6 17.0 19.1 35.7 24.6 21.6 29.2 29.4 23.8 31.5 43.3 35.2 54.5 27.4 26.5 26.7 36.4 34.6 15.6 30.3 26.2 33.7 25.5 44.1 28.4 21.0 15.4 46.5 31.5 37.6 17.7 43.4 38.4 24.0 21.0 31.9 21.4 24.6 32.3 18.3 29.9 12.1 22.0 24.8 25.1 20.2 27.3 42.6 26.8 20.1 39.5 24.1 46.9 27.2 26.2 20.8 44.8 31.8 24.7 30.9 23.4 29.3 34.0 25.6 23.8 25.6 27.1 41.2 20.0 26.1 19.7 35.0 20.7 26.8 34.6 37.5 28.3 26.0 22.3 35.0 24.1 27.9 33.8 SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457928-43464247 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB034889: AB_785899, HPA029005: AB_10610424" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.25e-2)" "unprognostic (6.41e-2)" "unprognostic (3.91e-2)" "prognostic unfavourable (3.86e-4)" "unprognostic (3.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "unprognostic (1.27e-3)" "unprognostic (6.03e-3)" "prognostic unfavourable (2.82e-4)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (4.31e-1)" "unprognostic (1.18e-2)" 24.9 35.9 21.7 29.3 31.5 57.0 34.7 30.6 23.0 26.7 21.4 29.5 44.4 20.3 32.1 36.9 23.3 35.6 26.7 18.3 21.4 18.5 30.3 41.4 25.5 26.3 33.9 17.0 41.4 48.3 30.4 47.8 29.0 24.2 30.3 26.7 26.3 32.0 30.2 25.6 27.9 30.0 24.5 17.8 38.8 29.3 27.0 30.5 49.4 36.7 38.6 34.4 21.3 20.7 12.3 17.3 14.7 24.2 15.3 22.1 14.6 15.1 10.9 31.4 20.4 18.1 25.0 23.5 21.3 13.5 19.3 16.3 22.7 19.2 30.0 16.0 25.2 21.3 32.4 40.6 26.0 8.8 17.8 25.2 21.6 25.8 22.4 29.7 19.5 42.3 21.8 17.2 15.8 18.0 18.2 19.0 18.3 18.1 38.2 35.4 18.4 16.2 22.2 19.6 24.2 22.6 25.4 24.2 31.4 26.7 38.9 34.8 21.9 34.9 18.8 19.5 14.4 16.7 22.0 24.7 15.1 39.8 24.5 22.5 13.6 14.7 14.5 6.7 15.8 24.2 17.5 12.3 16.6 15.0 17.3 12.2 22.1 20.7 7.2 15.3 19.0 14.8 13.2 14.6 21.7 31.5 30.6 23.0 21.4 18.5 33.9 17.0 24.2 30.5 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 8.2;lymphoid tissue: 5.2;pituitary gland: 9.0" "Group enriched" "Detected in some" 15 "Hep G2: 9.2;PC-3: 34.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 4.2;hypothalamus: 2.7" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" "Plasma membrane" "HPA066503: " "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.4 0.0 0.7 0.6 0.9 0.5 0.0 8.2 2.9 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.0 0.0 0.0 1.1 0.0 0.0 1.1 0.9 0.1 0.1 0.8 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 5.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 1.3 0.3 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 STAR "StAR, STARD1" ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38143649-38151265 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 311.3;ovary: 124.6" "Cell line enriched" "Detected in some" 5 "K-562: 99.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in some" 8 "basal ganglia: 10.6" "Cell type enriched" "Detected in single" 11 "basophil: 5.7" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced "CAB032598: AB_2115937, HPA023644: AB_10598916, HPA027318: AB_10601574" "unprognostic (1.60e-4)" "unprognostic (3.20e-2)" "unprognostic (9.17e-2)" "unprognostic (3.28e-2)" "unprognostic (9.22e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.12e-5)" "unprognostic (3.30e-2)" "unprognostic (2.36e-1)" "unprognostic (1.77e-3)" "unprognostic (6.65e-2)" "unprognostic (4.75e-9)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.16e-2)" 0.2 311.3 0.5 0.3 10.6 0.3 0.0 0.0 1.0 0.0 0.0 11.6 0.0 0.0 0.1 0.8 0.2 0.4 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.2 0.9 124.6 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.4 0.0 0.0 29.5 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.1 5.7 0.1 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.4 0.1 1.3 0.3 1.0 0.0 3.4 0.0 0.0 0.0 0.0 99.5 0.0 0.0 0.0 0.0 11.7 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 11.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 5.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.5 0.1 0.5 10.6 0.0 1.0 0.3 0.5 0.2 0.9 1.2 0.1 STAT1 "ISGF-3, STAT91" ENSG00000115415 "Signal transducer and activator of transcription 1" P42224 2 190964358-191020960 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 88.9;BJ hTERT+ SV40 Large T+ RasG12V: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000931, HPA000982, CAB004049" Approved Enhanced Nucleoplasm,Cytosol 22000 "Nucleoplasm, Cytosol" "CAB004049: AB_2197984, HPA000931: AB_1080100, HPA000982: AB_1080099" "unprognostic (6.90e-2)" "unprognostic (6.47e-2)" "unprognostic (4.27e-2)" "unprognostic (2.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.91e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-2)" "unprognostic (1.35e-1)" "prognostic favourable (1.75e-4)" "prognostic unfavourable (4.23e-4)" "unprognostic (1.35e-1)" "prognostic unfavourable (1.22e-5)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (3.35e-3)" "unprognostic (3.93e-2)" 27.9 27.2 17.4 47.8 17.8 19.5 20.4 15.0 21.7 21.0 19.8 14.9 17.5 22.7 17.1 27.4 23.3 14.5 29.0 25.5 15.6 22.2 34.9 35.7 29.4 57.9 16.9 18.8 24.3 18.7 20.0 24.0 24.3 23.6 23.6 20.3 17.9 47.5 18.0 20.1 17.4 24.6 24.8 21.8 49.0 24.2 13.5 10.4 58.7 36.2 18.5 30.2 29.3 16.5 10.8 16.2 55.0 47.1 22.7 54.1 44.6 8.8 9.4 4.4 7.4 19.5 26.4 14.4 13.4 41.1 88.9 100.1 14.9 10.2 3.6 8.5 28.7 7.5 5.0 10.7 17.6 30.1 4.1 16.3 7.4 8.7 13.6 8.4 10.2 17.5 6.8 16.4 5.8 10.7 8.9 21.6 16.3 7.2 6.3 10.6 6.2 15.5 5.3 12.1 4.4 11.7 11.0 6.2 6.0 15.8 6.0 41.2 6.3 10.4 9.4 17.7 10.4 15.3 8.6 36.8 53.8 3.4 13.5 7.2 8.1 13.0 36.9 27.0 14.7 47.1 19.9 10.8 35.1 21.0 16.2 8.6 35.8 26.0 55.0 22.7 27.6 7.4 54.1 44.6 17.4 17.8 15.0 21.7 15.6 22.2 16.9 18.8 23.6 10.4 STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 73.7;pituitary gland: 26.9" "Cell line enhanced" "Detected in many" "SCLC-21H: 49.9;U-87 MG: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 2.5;T-reg: 2.4" "Lineage enriched" "Detected in single" 6 "T-cells: 2.5" "Group enriched" "Detected in many" 5 "amygdala: 253.0;basal ganglia: 94.3;cerebral cortex: 362.2;hippocampal formation: 251.5" "Group enriched" "Detected in all" 8 "amygdala: 69.4;cerebral cortex: 158.6;hippocampal formation: 149.3" "CAB008372, HPA069176" Enhanced "Intracellular and membrane" "CAB008372: AB_592786, HPA069176: " "unprognostic (5.12e-3)" "prognostic unfavourable (3.63e-4)" "unprognostic (3.94e-2)" "prognostic unfavourable (1.94e-5)" "unprognostic (3.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.02e-8)" "unprognostic (1.11e-2)" "unprognostic (6.97e-2)" "unprognostic (3.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.70e-3)" "unprognostic (4.18e-6)" "unprognostic (2.65e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-3)" "unprognostic (6.20e-2)" 1.4 5.6 27.4 2.4 20.9 7.6 1.4 33.7 73.7 1.7 2.6 1.3 0.8 3.7 2.8 1.8 1.7 2.3 5.5 1.2 22.0 8.3 1.1 1.2 1.8 1.4 4.0 28.0 2.2 5.7 1.5 26.9 2.2 2.6 1.9 2.1 0.1 1.9 1.8 1.1 1.9 3.5 2.6 1.3 1.3 6.2 2.0 0.7 0.0 1.6 0.0 1.1 2.8 1.1 0.4 0.0 0.1 0.2 0.0 2.5 2.7 1.5 7.3 1.2 3.5 1.6 4.2 0.8 5.0 3.3 2.1 1.4 2.5 4.3 1.9 0.7 3.5 1.3 1.7 3.1 1.6 3.4 1.3 0.6 2.6 1.4 1.8 0.8 1.8 2.5 1.4 14.6 5.1 3.6 1.6 2.3 3.9 3.7 0.6 7.1 0.9 16.7 0.0 0.8 1.9 1.7 1.3 49.9 7.9 1.5 4.2 1.0 1.4 0.6 13.6 10.3 3.4 7.9 13.3 1.3 0.8 0.9 33.2 0.7 12.1 0.0 0.2 0.0 2.5 0.0 0.9 0.4 0.4 0.6 0.0 0.1 0.8 0.3 0.1 0.0 0.0 0.0 2.4 2.7 27.4 20.9 33.7 49.9 22.0 8.3 4.0 28.0 2.6 0.7 STX4 "p35-2, STX4A" ENSG00000103496 "Syntaxin 4" Q12846 16 31032889-31042975 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001330 Approved Enhanced "Plasma membrane" "Plasma membrane" "HPA001330: AB_1080167" "unprognostic (2.31e-3)" "prognostic favourable (3.65e-4)" "unprognostic (3.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.74e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "unprognostic (5.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.01e-2)" "unprognostic (3.12e-1)" "unprognostic (1.16e-2)" "prognostic unfavourable (2.88e-9)" "unprognostic (6.90e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.26e-2)" 26.5 28.2 28.6 23.8 29.6 14.1 23.5 24.2 28.0 21.4 24.0 24.4 16.9 28.3 24.1 19.8 26.4 19.6 23.7 24.6 26.7 18.0 21.7 25.2 25.8 22.5 38.1 22.3 22.7 19.3 33.6 14.9 27.0 32.4 19.8 22.0 14.0 21.3 21.8 30.3 32.7 26.7 27.7 26.1 31.4 22.7 10.7 31.5 19.2 21.3 17.3 26.7 25.4 29.4 11.9 14.8 20.6 18.2 18.2 14.9 8.6 18.2 26.2 5.9 13.2 20.0 20.4 12.7 16.9 29.9 18.1 18.7 8.0 19.9 12.4 22.0 29.9 13.3 5.5 19.7 17.4 22.2 16.8 8.9 18.3 21.8 22.7 10.3 30.1 19.4 13.8 31.3 23.4 24.0 10.4 14.5 32.1 28.7 9.7 15.9 12.3 14.1 8.3 17.8 16.1 18.0 13.6 4.9 9.3 14.9 15.4 6.2 12.3 13.7 25.7 18.4 8.2 20.6 9.4 15.6 12.6 5.4 27.7 16.7 11.1 14.6 17.7 20.6 14.9 18.2 12.9 9.7 12.5 14.5 14.8 11.9 9.5 12.2 18.5 18.2 15.8 8.6 6.8 8.6 28.6 29.6 24.2 28.0 26.7 18.0 38.1 22.3 32.4 31.5 SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61515313-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.4;prostate: 36.9;salivary gland: 37.7" "Cell line enhanced" "Detected in some" "BJ hTERT+: 15.0;hTERT-HME1: 39.3;RT4: 16.0;SCLC-21H: 12.7;SK-BR-3: 17.9;T-47d: 17.5" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavourable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavourable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" 2.5 3.7 16.2 1.4 22.7 0.6 6.9 22.8 46.4 2.8 4.0 3.2 0.0 2.1 2.0 1.9 1.9 1.7 1.4 11.1 11.8 7.8 4.4 28.2 1.7 0.8 4.9 23.6 1.2 11.9 2.2 22.2 12.7 8.8 36.9 4.2 2.4 37.7 1.3 2.8 1.6 3.3 1.8 1.5 1.8 3.4 2.5 3.0 0.0 3.5 0.6 0.8 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.6 0.8 0.2 0.0 0.4 6.4 4.6 0.1 15.0 0.2 0.2 1.4 3.0 0.0 0.2 0.0 3.0 0.4 0.1 0.1 0.1 0.7 0.0 0.6 0.8 0.4 0.0 0.0 0.2 3.5 1.8 39.3 0.0 0.0 0.1 0.2 9.3 0.0 0.1 1.0 6.3 0.0 0.3 0.7 0.0 16.0 12.7 2.3 0.8 17.9 0.1 17.5 0.0 0.0 3.7 1.4 4.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 22.7 22.8 37.5 11.8 7.8 4.9 23.6 8.8 3.0 SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469042 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.6" "Group enriched" "Detected in some" 4 "HEK 293: 8.7;RT4: 15.2;SH-SY5Y: 11.4;TIME: 17.0" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" 0.5 6.0 7.5 0.7 7.4 0.5 2.8 23.6 10.2 1.7 0.8 15.5 5.6 0.5 3.8 0.6 0.5 0.9 0.9 1.4 7.5 5.3 6.0 9.8 0.7 0.5 11.1 5.6 0.8 4.0 1.2 5.1 0.5 7.1 3.5 0.7 3.3 0.7 10.5 0.5 0.7 0.8 1.0 7.9 0.5 0.7 2.8 11.5 0.0 3.6 0.0 0.5 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.9 0.0 0.0 0.0 0.0 15.2 2.7 11.4 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 7.4 23.6 6.4 7.5 5.3 11.1 5.6 7.1 11.5 SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100674491-100732123 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 36.2;ovary: 47.3;pituitary gland: 41.9" "Cell line enhanced" "Detected in many" "HAP1: 14.9;HMC-1: 30.9;RT4: 20.3;TIME: 17.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "neutrophil: 5.1" "Lineage enriched" "Detected in single" 9 "granulocytes: 5.1" "Region enriched" "Detected in single" 5 "hypothalamus: 35.1" "Not detected" "Not detected" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles 6100000 Vesicles "HPA001475: AB_1080172, HPA001589: AB_1080174, HPA075138: " "unprognostic (7.82e-3)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (6.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-1)" "unprognostic (1.07e-3)" "unprognostic (5.62e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.60e-2)" 3.8 3.1 9.1 2.8 9.5 1.6 4.4 4.3 8.4 18.1 5.3 6.6 4.8 1.7 36.2 5.4 2.6 10.0 2.9 2.1 11.9 6.0 4.2 7.1 3.0 0.7 9.8 2.7 47.3 8.8 1.3 41.9 2.6 9.4 9.2 6.8 1.3 3.8 6.0 4.5 1.4 3.0 22.5 7.8 2.3 5.3 7.8 9.5 0.0 6.2 1.1 1.4 4.3 9.4 0.5 0.3 5.1 0.3 0.5 0.4 2.3 0.1 3.0 0.8 0.0 4.4 2.5 0.0 3.8 2.5 4.1 7.4 0.3 3.8 0.0 1.0 2.7 3.4 14.9 1.3 4.4 0.0 1.3 0.0 5.1 0.2 1.1 0.0 30.9 0.9 0.3 3.7 0.2 10.4 1.4 0.0 1.9 1.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 3.7 20.3 7.5 0.3 1.5 5.9 0.8 3.6 0.3 17.5 2.1 4.7 10.7 0.9 0.0 0.0 0.0 2.7 0.0 2.4 1.1 0.3 0.5 0.2 0.2 0.2 0.3 0.2 0.2 0.0 0.5 0.4 0.2 5.1 0.5 0.2 0.3 0.1 2.3 9.1 9.5 4.3 8.4 11.9 6.0 9.8 2.7 9.4 9.5 TARDBP "ALS10, TDP-43" ENSG00000120948 "TAR DNA binding protein" Q13148 1 11012344-11026420 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Amyotrophic lateral sclerosis, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003703, HPA017284" Supported Enhanced Nucleoplasm 13000 Nucleoplasm "CAB003703: AB_425904, HPA017284: AB_1857775" "unprognostic (3.72e-3)" "prognostic favourable (1.15e-5)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (8.52e-2)" "unprognostic (4.10e-2)" "prognostic unfavourable (1.20e-7)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (4.75e-3)" "unprognostic (2.24e-1)" "unprognostic (2.54e-2)" "unprognostic (2.27e-3)" "unprognostic (2.27e-1)" "unprognostic (1.87e-1)" "unprognostic (2.86e-1)" "unprognostic (2.71e-2)" 36.1 38.1 52.3 43.3 62.9 31.7 42.8 86.2 61.8 38.7 39.8 47.6 37.5 39.8 45.8 47.2 47.8 37.9 32.4 40.8 49.5 36.7 39.3 48.3 40.2 52.8 59.0 45.2 53.0 39.1 60.2 68.1 44.2 46.5 43.3 52.9 38.4 41.7 45.3 57.1 43.0 43.4 50.5 44.7 46.1 38.1 34.5 62.6 52.2 46.7 38.0 63.5 38.1 47.9 29.4 31.7 16.5 24.8 33.6 31.1 17.0 52.0 35.7 61.3 31.4 33.3 28.0 36.2 35.8 31.6 58.9 44.1 42.2 38.5 69.4 26.3 39.7 37.3 74.4 41.6 77.6 37.2 35.9 52.5 59.4 56.1 27.3 63.0 35.0 22.8 47.3 41.3 33.9 41.7 67.5 39.1 49.8 42.0 46.0 51.1 48.9 32.0 54.6 49.2 44.1 42.4 38.6 41.9 34.6 48.7 38.6 27.6 38.7 44.5 38.0 39.6 46.4 32.5 51.4 29.2 36.1 73.4 25.9 63.3 41.9 16.3 19.6 16.5 25.4 24.8 31.1 29.4 26.0 24.6 31.7 21.2 25.9 27.7 7.9 33.6 23.6 22.2 26.8 17.0 52.3 62.9 86.2 61.8 49.5 36.7 59.0 45.2 46.5 62.6 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950250-113167678 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 12.1;non-classical monocyte: 33.1" "Lineage enriched" "Detected in many" 13 "monocytes: 33.1" "Group enriched" "Detected in many" 8 "midbrain: 84.5;thalamus: 98.3" "Group enriched" "Detected in all" 5 "midbrain: 190.1;pons and medulla: 104.8;thalamus: 169.1" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 27.4 10.3 8.7 18.7 10.0 7.3 46.4 5.4 10.3 27.4 34.2 15.4 28.1 21.0 26.6 14.9 12.6 18.2 15.3 13.5 8.1 17.9 10.2 22.9 26.9 13.9 8.5 9.0 25.6 13.9 16.5 17.9 24.0 10.2 14.4 23.7 13.9 14.9 52.8 13.7 17.6 40.4 18.0 13.9 27.3 24.0 10.6 10.1 6.6 14.3 9.3 7.0 21.5 16.3 0.0 1.7 2.5 33.1 0.0 0.6 1.1 7.0 18.5 20.3 19.6 10.6 7.1 24.2 5.0 9.8 3.5 4.3 12.2 21.5 0.0 5.7 9.4 5.0 6.9 8.7 4.5 0.8 6.4 5.0 12.3 11.3 11.3 1.9 1.8 12.5 3.2 5.5 9.3 5.9 5.1 0.3 4.1 13.8 3.1 1.2 14.6 10.7 8.9 14.9 3.2 7.6 9.9 0.4 6.2 7.6 7.6 8.1 4.9 1.0 13.6 3.3 9.6 8.4 10.3 1.3 0.1 0.1 3.3 4.2 7.4 0.1 1.8 0.1 0.6 12.1 0.4 0.0 0.1 0.5 1.7 0.0 0.1 0.3 2.5 0.0 33.1 0.0 0.0 1.1 8.7 10.0 5.4 10.3 8.1 17.9 8.5 9.0 10.2 10.1 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039016-68050895 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 40.0;RPMI-8226: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favourable (9.45e-6)" 25.8 24.1 5.0 20.1 7.2 39.5 10.2 1.3 5.4 20.1 21.8 3.9 19.9 20.1 14.1 27.1 11.9 12.5 16.4 5.9 2.4 1.6 8.9 25.2 24.1 20.7 7.1 2.2 11.4 69.6 2.6 4.7 14.4 6.9 15.7 4.1 6.8 18.3 11.0 3.5 5.2 25.8 10.8 7.7 44.7 17.4 4.2 5.5 7.5 11.7 8.3 24.3 13.0 13.4 3.3 13.4 40.4 36.8 8.2 4.9 10.7 9.1 16.8 0.2 0.0 7.7 6.1 11.8 18.2 8.8 5.2 5.0 0.3 27.4 0.8 9.9 6.4 11.5 1.1 7.0 1.1 23.7 0.5 6.3 20.5 5.4 7.2 4.6 40.0 7.0 4.1 6.4 0.4 3.5 3.3 2.5 1.7 3.1 0.2 27.8 1.0 4.3 7.8 0.2 39.8 4.9 5.2 0.9 0.2 7.6 10.0 4.9 10.9 12.0 12.4 10.1 8.0 28.1 3.2 0.4 0.3 1.3 22.6 7.7 4.8 5.5 16.6 18.8 4.5 28.8 3.7 3.3 3.4 4.9 13.4 2.2 2.0 2.1 40.4 8.2 36.8 9.0 3.3 10.7 5.0 7.2 1.3 5.4 2.4 1.6 7.1 2.2 6.9 5.5 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847613 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 65.5" "Group enriched" "Detected in some" 4 "AF22: 31.7;SH-SY5Y: 59.0" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in some" 41 "cerebellum: 4.7;pons and medulla: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 11.2" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm Nucleoplasm "HPA034683: AB_10670966, HPA062942: " "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.2 3.0 0.0 0.0 0.0 0.0 9.4 4.7 0.0 0.2 0.2 0.0 8.8 0.0 0.0 65.5 5.8 0.0 0.0 0.1 0.0 0.1 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 6.3 0.1 0.0 12.2 7.0 0.6 0.0 6.3 0.0 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 59.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.1 0.0 6.3 0.0 TIAM1 ENSG00000156299 "T cell lymphoma invasion and metastasis 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 110.1" "Cell line enhanced" "Detected in many" "BEWO: 18.9;HEL: 18.3;HMC-1: 16.0;RT4: 19.0;SCLC-21H: 17.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 110.1" "Group enriched" "Detected in many" 5 "classical monocyte: 10.7;intermediate monocyte: 9.6;memory CD4 T-cell: 8.3;myeloid DC: 5.9;naive CD4 T-cell: 10.9;NK-cell: 6.9;non-classical monocyte: 12.4;T-reg: 16.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 574.6" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 3.3 11.4 13.4 5.3 12.4 2.1 4.4 110.1 15.1 10.1 2.2 9.7 0.5 1.5 7.9 3.0 18.9 9.4 4.0 2.1 11.6 7.0 1.7 3.7 4.1 8.8 6.2 7.9 1.5 1.9 0.3 4.2 4.4 8.9 3.7 2.8 7.0 2.2 3.1 0.7 20.4 1.7 10.0 6.4 4.2 2.1 5.9 7.1 6.2 1.3 5.3 9.3 8.1 5.0 0.1 5.9 0.6 12.4 6.9 16.8 3.6 1.5 0.5 11.9 0.7 0.2 2.8 18.9 0.0 0.0 1.4 0.5 0.1 2.1 4.0 0.8 0.3 2.8 1.4 2.4 2.4 0.3 6.5 18.3 0.3 0.1 0.3 0.0 16.0 1.2 0.8 8.1 3.2 0.0 0.0 6.0 6.0 7.7 2.8 0.1 3.8 5.1 3.6 3.7 0.0 1.8 19.0 17.9 4.4 0.8 6.2 0.7 2.5 0.0 0.1 1.7 6.9 0.0 0.8 6.7 5.0 3.6 4.0 1.4 13.1 0.6 10.7 0.0 0.3 9.6 2.1 0.1 8.3 1.6 5.9 0.0 10.9 0.6 0.6 6.9 12.4 0.3 16.8 3.6 13.4 12.4 110.1 14.4 11.6 7.0 6.2 7.9 8.9 7.1 TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153705702 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 72.9" "Cell line enhanced" "Detected in some" "HSkMC: 7.4;hTCEpi: 7.4;RPTEC TERT1: 7.6;RT4: 9.3;THP-1: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 29.5;intermediate monocyte: 28.1;myeloid DC: 19.1;neutrophil: 72.9;non-classical monocyte: 18.4" "Group enriched" "Detected in many" 46 "dendritic cells: 19.1;granulocytes: 72.9;monocytes: 29.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" 16.3 6.9 6.9 30.0 11.1 34.6 7.3 1.4 5.3 4.7 4.7 3.0 9.3 2.2 3.1 8.0 3.2 7.2 10.0 7.2 6.7 3.3 9.8 7.3 31.1 37.8 12.4 1.4 4.2 5.1 1.1 4.4 6.4 9.9 5.5 1.9 3.3 15.0 9.9 2.5 3.1 4.0 6.6 21.9 29.3 3.9 4.8 9.5 0.9 3.3 1.0 8.5 7.3 3.5 0.2 19.1 72.9 29.5 0.8 0.2 9.3 3.9 0.0 0.1 0.0 0.5 1.6 0.0 0.0 0.3 0.3 0.5 1.9 0.2 0.0 0.4 0.0 3.5 0.4 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 6.8 0.5 7.4 7.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.4 1.5 0.1 0.0 0.0 7.6 9.3 0.0 0.2 0.4 0.0 1.8 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.9 6.2 29.5 0.2 0.0 28.1 0.0 0.0 0.1 0.0 19.1 0.2 0.2 0.0 72.9 0.8 18.4 0.1 0.0 9.3 6.9 11.1 1.4 5.3 6.7 3.3 12.4 1.4 9.9 9.5 TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26973195-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favourable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" 12.0 27.6 12.1 8.1 17.4 18.5 15.9 7.9 18.9 12.4 17.2 18.1 13.1 10.7 10.9 16.6 27.8 12.7 16.4 10.6 11.7 11.6 69.8 39.9 15.9 15.0 13.0 11.6 12.1 52.6 15.4 33.2 11.0 10.7 14.5 19.7 20.5 21.9 14.2 5.8 15.4 12.8 13.2 13.9 12.0 14.9 11.0 10.6 31.2 14.1 12.3 17.1 15.3 16.5 10.5 10.6 16.0 6.9 11.8 11.4 3.9 8.5 20.5 12.2 14.7 18.5 12.3 64.1 10.6 17.3 8.8 15.1 11.2 36.7 11.5 13.7 10.0 9.4 12.7 72.0 12.2 11.3 7.6 17.3 25.7 21.3 12.3 62.3 12.2 7.5 61.4 18.8 16.9 23.1 7.4 7.9 13.3 17.6 30.4 36.2 24.8 12.2 28.5 19.2 20.4 15.2 39.3 2.0 10.8 13.1 7.1 18.7 19.4 13.2 8.7 7.7 12.6 21.1 13.1 4.8 12.3 21.6 14.8 21.2 11.6 8.6 6.9 16.0 6.0 6.9 5.7 7.3 7.6 7.8 10.2 10.5 10.9 7.2 7.8 11.8 3.5 10.6 11.4 3.9 12.1 17.4 7.9 18.9 11.7 11.6 13.0 11.6 10.7 10.6 TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575567-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.6;lymphoid tissue: 28.0" "Group enriched" "Detected in some" 5 "HDLM-2: 10.0;HMC-1: 9.6;NB-4: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "non-classical monocyte: 10.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.5;monocytes: 10.8;T-cells: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 10140 "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" 2.3 1.2 0.6 15.6 1.0 14.6 1.2 0.4 1.8 1.7 1.3 3.7 0.3 1.3 1.1 0.4 1.5 0.9 2.3 2.0 0.5 0.3 2.6 1.9 9.5 8.0 0.8 0.0 0.6 0.7 0.5 0.5 3.2 2.0 0.7 0.7 0.4 2.2 0.8 0.4 2.7 4.1 0.7 1.0 28.0 1.0 0.4 0.5 2.1 0.6 5.3 14.7 1.2 0.4 1.3 1.2 3.5 10.8 0.5 6.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 10.0 0.0 1.8 0.0 0.0 0.0 0.8 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.9 0.0 0.0 1.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.7 0.0 4.1 6.5 6.6 1.3 3.1 2.4 1.2 1.3 0.9 1.0 3.5 0.5 10.8 0.7 2.2 2.1 0.6 1.0 0.4 1.8 0.5 0.3 0.8 0.0 2.0 0.5 TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523507 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.1" "Cell line enhanced" "Detected in many" "BEWO: 20.5;CAPAN-2: 14.6;HMC-1: 67.6;RPTEC TERT1: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 42.4;classical monocyte: 25.6;intermediate monocyte: 39.5;neutrophil: 50.3;non-classical monocyte: 38.3" "Group enriched" "Detected in all" 5 "granulocytes: 50.3;monocytes: 39.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054938 Uncertain Approved Microtubules "Secreted to blood" 67430 Microtubules "HPA054938: " "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavourable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" 30.9 22.1 3.4 14.6 4.7 2.0 23.3 3.0 5.4 31.4 25.8 4.4 17.1 20.6 13.0 10.3 33.3 9.6 10.7 9.9 3.8 3.2 115.1 44.4 91.5 23.5 5.5 3.4 13.5 11.6 10.9 6.7 100.8 6.7 37.6 19.5 12.0 50.6 12.9 13.9 13.0 54.0 7.9 5.6 35.8 9.5 6.0 4.6 8.3 28.2 17.7 16.1 22.4 24.0 3.4 9.5 50.3 39.5 9.3 7.0 11.9 3.3 0.1 0.0 0.0 2.4 1.8 20.5 0.0 0.1 1.0 1.6 0.0 14.6 2.1 9.8 0.0 14.4 0.0 1.8 0.2 5.2 0.0 0.0 0.4 0.3 0.1 3.8 67.6 2.4 2.3 0.4 0.0 7.4 0.0 2.4 0.0 0.0 0.4 5.1 0.0 0.1 0.7 0.0 0.9 34.1 1.3 0.0 0.1 7.5 0.3 0.1 4.1 2.2 0.3 0.0 0.0 0.0 0.2 2.6 0.3 2.6 0.2 2.2 0.0 42.4 25.6 2.7 2.3 39.5 3.1 3.2 6.4 3.5 9.5 3.4 4.7 1.8 50.3 9.3 38.3 0.6 7.0 11.9 3.4 4.7 3.0 5.4 3.8 3.2 5.5 3.4 6.7 4.6 TRH ENSG00000170893 "Thyrotropin releasing hormone" P20396 3 129974305-129977938 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.9;cervix, uterine: 23.6;endometrium 1: 17.5" "Cell line enhanced" "Detected in some" "REH: 3.1;T-47d: 2.9" "Cancer enhanced" "Detected in some" "breast cancer: 13.3;endometrial cancer: 10.2" "Group enriched" "Detected in many" 14 "hypothalamus: 33.9;pons and medulla: 33.8" "Group enriched" "Detected in some" 11 "intermediate monocyte: 1.1;non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Group enriched" "Detected in many" 5 "hypothalamus: 204.6;olfactory region: 182.2" "Low region specificity" "Detected in many" HPA035596 Enhanced "Secreted in other tissues" "HPA035596: " "unprognostic (1.22e-1)" "unprognostic (8.94e-2)" "unprognostic (5.82e-3)" "unprognostic (5.24e-2)" "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (4.44e-2)" "unprognostic (3.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" 0.3 0.1 0.4 0.2 2.4 2.8 0.9 0.3 1.7 23.6 0.1 0.1 0.6 0.2 17.5 0.1 0.1 2.3 0.1 0.5 2.0 33.9 0.1 0.1 0.6 0.1 0.4 0.8 3.2 0.1 0.1 0.1 0.3 33.8 0.1 0.1 6.3 1.0 0.2 0.2 0.5 0.1 0.4 3.6 0.1 0.1 0.8 0.0 0.8 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 2.9 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 2.4 0.3 1.7 2.0 33.9 0.4 0.8 33.8 0.0 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.0;salivary gland: 47.5" "Cell line enhanced" "Detected in many" "HHSteC: 87.0;hTCEpi: 53.9;hTERT-HME1: 62.7;SK-MEL-30: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm Nucleoplasm "HPA015272: AB_1858269, HPA055442: " "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.70e-4)" "prognostic unfavourable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavourable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 4.8 8.7 1.6 2.8 1.5 9.7 6.0 3.8 4.2 2.5 1.8 1.2 3.6 1.0 2.1 3.1 9.8 1.1 2.7 3.0 1.4 2.0 3.3 39.0 8.2 7.3 1.0 2.4 4.4 13.8 2.0 10.5 6.2 1.6 3.9 1.6 3.7 47.5 5.3 1.5 6.5 2.5 1.3 0.7 7.9 4.4 2.7 0.6 6.7 27.2 4.1 7.0 2.7 5.3 15.5 4.7 3.3 4.4 6.6 11.4 5.1 10.9 5.5 0.7 1.6 1.9 2.5 4.7 3.2 8.7 3.1 6.5 11.5 5.4 4.7 3.2 2.9 8.8 3.0 14.6 2.9 1.7 2.1 3.6 1.2 18.7 87.0 9.2 1.8 10.1 53.9 5.8 62.7 6.0 12.6 21.3 0.3 10.1 0.5 11.2 1.6 18.1 2.1 0.9 10.1 3.6 4.4 2.0 3.2 0.7 26.5 79.1 7.7 24.5 3.4 1.7 2.9 0.0 5.0 7.4 9.5 8.4 1.4 8.1 6.0 2.5 4.4 1.0 10.0 3.4 7.1 15.5 9.3 11.4 4.7 10.2 10.7 7.6 3.3 6.6 1.7 2.1 6.4 5.1 1.6 1.5 3.8 4.2 1.4 2.0 1.0 2.4 1.6 0.6 TRPM2 "EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7" ENSG00000142185 "Transient receptor potential cation channel subfamily M member 2" O94759 21 44350163-44443081 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sodium transport, Transport" "Calcium channel, Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.9" "Cell line enhanced" "Detected in some" "HL-60: 16.7;NB-4: 23.7;THP-1: 29.2;U-937: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 7.3;plasmacytoid DC: 14.5" "Group enriched" "Detected in many" 8 "dendritic cells: 14.5;monocytes: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030976, HPA035260" Enhanced Approved "Nuclear membrane" "Nuclear membrane" "HPA030976: , HPA035260: " "unprognostic (3.61e-2)" "unprognostic (2.18e-1)" "unprognostic (7.55e-2)" "prognostic favourable (9.28e-4)" "unprognostic (6.49e-2)" "unprognostic (4.54e-2)" "unprognostic (5.17e-2)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (2.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (4.39e-6)" "unprognostic (1.40e-1)" "unprognostic (3.31e-2)" "unprognostic (8.88e-3)" "prognostic favourable (7.59e-4)" 5.4 4.5 7.4 8.6 7.8 29.9 3.9 14.5 16.3 2.9 4.5 6.9 0.0 4.4 1.9 1.5 2.1 2.6 5.7 1.8 7.8 8.9 2.1 2.0 3.8 8.2 8.5 10.4 1.5 2.4 2.1 2.1 7.1 11.7 1.9 3.0 2.6 2.9 1.3 1.3 2.3 5.1 3.2 9.7 8.1 3.1 1.9 7.3 2.0 1.7 0.0 4.8 4.9 1.7 1.4 14.5 0.4 7.3 0.5 1.1 1.8 8.3 3.1 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.2 0.1 0.0 0.0 0.2 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 16.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 23.7 0.0 9.8 0.9 3.0 3.2 0.0 0.0 6.1 0.0 0.0 9.8 0.0 11.6 29.2 0.0 0.5 8.9 0.0 0.3 0.1 12.4 0.0 0.0 27.6 0.0 0.0 7.3 0.0 1.0 2.6 0.6 0.3 0.3 0.4 2.5 1.4 0.3 0.4 0.4 0.5 2.0 14.5 1.1 1.8 7.4 7.8 14.5 16.3 7.8 8.9 8.5 10.4 11.7 7.3 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 32.5;SK-BR-3: 21.4" "Cancer enhanced" "Detected in all" "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 5.4;granulocytes: 4.9;monocytes: 6.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" 6500 "Nucleoplasm, Plasma membrane" "HPA041169: " "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favourable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favourable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 6.7 3.8 3.5 13.7 3.7 4.3 8.5 3.0 6.8 8.2 25.2 4.5 8.6 20.6 7.9 9.1 7.7 5.4 24.8 9.3 2.7 2.2 14.2 23.6 9.4 3.5 2.6 5.7 2.7 17.4 3.4 3.3 5.0 6.9 20.2 11.4 10.6 16.2 13.2 16.4 16.1 26.8 9.4 2.5 3.4 18.3 4.2 2.2 0.4 10.1 11.5 6.8 9.9 8.6 1.1 5.4 4.9 6.8 1.0 0.7 2.1 6.0 4.5 1.1 5.1 3.8 3.6 3.6 5.1 3.0 1.4 1.9 3.3 9.5 0.2 1.3 3.4 8.0 0.7 1.5 0.6 0.1 1.6 1.0 1.9 2.0 3.4 0.1 6.6 4.3 7.0 2.6 1.2 2.4 2.4 1.2 3.5 9.1 0.4 0.5 0.6 6.9 2.2 1.0 0.3 2.4 32.5 0.4 1.1 2.1 21.4 1.1 11.6 2.0 6.1 7.6 4.3 4.2 0.1 2.2 2.2 0.2 4.3 4.0 2.8 2.7 6.8 1.1 0.6 4.0 0.5 0.8 0.5 0.4 5.4 1.1 0.6 0.7 4.9 1.0 1.5 4.9 0.3 2.1 3.5 3.7 3.0 6.8 2.7 2.2 2.6 5.7 6.9 2.2 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783085-109833401 "Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease mutation, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 32.6" "Cell line enhanced" "Detected in many" "BEWO: 8.9;BJ hTERT+: 9.1;EFO-21: 8.0;HaCaT: 14.5;HUVEC TERT2: 8.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 11 "pons and medulla: 15.0" "Cell type enriched" "Detected in single" 7 "classical monocyte: 3.0" "Lineage enriched" "Detected in single" 7 "monocytes: 3.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favourable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.3 0.9 0.3 0.9 0.4 0.1 3.3 0.2 0.6 2.3 0.4 3.2 0.0 0.6 0.8 3.7 9.5 5.6 5.2 1.6 1.3 0.2 11.6 7.8 2.6 1.8 0.2 0.0 0.6 7.1 0.1 4.3 11.1 15.0 6.2 0.3 12.6 32.6 1.4 0.2 6.5 0.3 0.9 0.3 3.5 0.9 0.7 0.1 0.2 0.9 2.6 8.7 2.6 1.7 0.0 0.4 0.0 3.0 0.0 0.0 0.4 2.5 0.1 0.0 0.0 1.9 1.8 8.9 4.2 9.1 1.2 0.5 0.0 6.3 0.0 8.0 5.4 14.5 1.1 0.0 0.3 0.0 2.1 0.0 0.0 3.6 0.7 0.0 0.0 3.3 2.0 3.3 0.0 8.3 0.8 0.0 0.4 5.3 0.0 0.0 1.6 0.2 0.0 0.5 0.0 0.0 5.1 0.0 0.0 0.3 0.6 2.5 1.2 0.4 5.1 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.2 0.6 1.3 0.2 0.2 0.0 15.0 0.1 UCP3 SLC25A9 ENSG00000175564 "Uncoupling protein 3" P55916 11 74000281-74009435 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skeletal muscle: 99.6" "Cell line enriched" "Detected in many" 4 "HDLM-2: 17.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebellum: 1.1" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010771, HPA072225" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "CAB010771: AB_261839, HPA072225: " "unprognostic (3.76e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-1)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-2)" "unprognostic (3.95e-3)" "unprognostic (6.61e-2)" "unprognostic (1.25e-1)" "unprognostic (8.58e-2)" "unprognostic (2.13e-4)" "unprognostic (1.61e-2)" "unprognostic (3.25e-6)" "unprognostic (2.68e-1)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.50e-4)" 0.9 0.2 0.2 0.3 0.2 0.6 0.2 1.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.5 0.9 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.2 0.2 1.0 0.2 99.6 0.3 0.2 0.2 0.2 0.5 0.1 0.6 0.2 0.2 0.6 6.4 0.8 0.2 0.2 0.8 0.1 0.7 0.3 0.2 2.1 0.4 0.2 2.0 2.0 1.7 0.8 0.4 0.4 0.5 0.5 0.5 0.3 0.5 0.4 1.0 0.3 0.4 2.2 0.8 0.4 0.8 17.8 0.7 0.4 2.4 0.2 0.6 1.2 1.7 0.5 1.4 1.3 0.1 0.6 0.5 1.4 0.7 1.2 0.8 1.6 1.0 1.4 1.6 4.2 0.6 1.1 0.6 1.2 1.2 0.5 0.9 0.7 0.2 1.1 0.4 0.3 1.4 0.6 1.2 1.6 1.7 0.8 0.3 1.1 0.6 0.0 0.3 0.7 2.1 0.1 0.9 0.0 1.5 1.8 0.0 0.8 0.6 1.2 0.1 0.2 0.0 0.1 0.4 0.4 0.2 0.2 1.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 UPRT "DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3" ENSG00000094841 "Uracil phosphoribosyltransferase homolog" Q96BW1 X 75274085-75304600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000805 Uncertain Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA000805: AB_1080482" "unprognostic (3.12e-3)" "unprognostic (5.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (1.18e-2)" "unprognostic (4.62e-2)" "unprognostic (1.04e-3)" "unprognostic (9.64e-2)" "unprognostic (1.37e-2)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "prognostic favourable (4.14e-4)" "unprognostic (6.09e-2)" "unprognostic (2.54e-2)" "unprognostic (2.74e-1)" "unprognostic (4.53e-3)" 8.8 15.3 14.6 7.9 15.8 14.9 10.7 20.3 18.7 11.5 9.9 10.8 10.8 14.2 10.0 12.5 13.0 10.2 8.4 12.0 13.1 17.7 15.5 11.3 10.0 10.7 14.9 9.6 8.7 14.1 18.7 19.5 7.6 13.2 12.8 11.0 9.1 13.1 8.6 13.3 7.4 10.5 14.0 10.9 11.0 13.9 3.0 12.4 10.6 13.9 6.5 11.9 9.1 7.9 8.3 11.1 8.9 16.4 14.7 13.3 7.4 7.7 5.5 6.1 5.7 6.6 7.1 5.8 5.4 6.4 5.9 6.6 4.8 5.2 10.8 4.7 5.6 3.4 14.0 4.9 9.5 9.8 5.6 6.8 5.8 6.1 6.4 13.3 14.1 5.4 3.4 8.1 4.2 10.2 7.9 10.9 15.3 3.3 15.0 8.1 12.4 9.0 7.1 16.1 5.2 15.0 4.5 0.4 6.4 7.6 7.9 7.4 3.6 8.5 8.5 7.4 4.5 13.6 4.6 7.4 24.1 10.5 7.9 14.6 4.7 5.1 7.4 8.9 8.3 10.7 9.5 8.3 8.3 8.5 11.1 7.2 10.5 9.3 1.3 14.7 16.4 5.0 13.3 7.4 14.6 15.8 20.3 18.7 13.1 17.7 14.9 9.6 13.2 12.4 USF1 "bHLHb11, MLTFI, UEF" ENSG00000158773 "Upstream transcription factor 1" P22415 1 161039251-161045977 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001480, HPA036233, HPA036535" Supported Enhanced Nucleoplasm Nucleoplasm "CAB001480: AB_2213986, HPA036233: , HPA036535: " "unprognostic (3.66e-2)" "unprognostic (2.79e-2)" "unprognostic (9.12e-3)" "unprognostic (2.17e-1)" "unprognostic (9.40e-2)" "prognostic favourable (8.70e-4)" "unprognostic (1.59e-3)" "unprognostic (2.94e-2)" "unprognostic (3.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "prognostic unfavourable (6.01e-12)" "unprognostic (1.24e-3)" "unprognostic (3.29e-1)" "unprognostic (4.08e-1)" "prognostic favourable (1.95e-5)" 15.4 17.0 21.6 16.9 24.4 14.3 13.8 31.0 27.6 15.2 17.6 15.6 15.6 17.7 15.1 15.5 12.6 17.1 16.2 17.4 21.6 22.1 15.2 19.1 16.7 23.8 19.7 19.4 17.2 9.8 19.0 12.3 17.3 17.1 14.4 18.0 14.7 13.8 19.0 27.4 14.6 17.8 18.0 18.3 26.7 13.7 8.5 18.7 21.9 16.1 13.5 30.3 18.5 13.8 3.9 5.7 8.6 4.7 2.0 4.0 2.0 8.2 12.5 15.0 17.4 20.3 11.6 20.2 6.9 15.0 21.6 16.9 8.7 10.4 10.7 14.7 11.5 10.3 17.6 11.0 12.2 9.9 10.4 9.1 10.5 9.1 11.9 12.7 12.9 9.4 11.0 15.6 12.8 20.2 15.0 11.5 13.5 9.6 19.6 13.9 30.9 16.4 17.1 11.7 12.9 10.7 13.2 8.5 16.3 12.6 16.4 8.7 13.7 41.5 11.8 10.9 6.9 6.6 11.1 9.7 12.3 16.9 9.3 12.5 8.2 4.7 4.7 2.7 4.0 4.5 2.4 3.4 2.5 2.9 5.4 3.9 2.7 2.6 8.6 2.0 4.2 5.7 2.7 2.0 21.6 24.4 31.0 27.6 21.6 22.1 19.7 19.4 17.1 18.7 VAMP2 "SYB2, VAMP-2" ENSG00000220205 "Vesicle associated membrane protein 2" P63027 17 8159149-8163546 "FDA approved drug targets, Predicted membrane proteins, Transporters" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 168.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" CAB078785 Supported "CAB078785: " "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (1.58e-2)" "prognostic favourable (1.08e-4)" "unprognostic (2.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (7.28e-2)" "unprognostic (5.15e-2)" "unprognostic (1.55e-1)" "prognostic favourable (3.83e-6)" "unprognostic (8.27e-2)" "prognostic favourable (9.76e-8)" "unprognostic (1.21e-2)" "unprognostic (7.00e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" 22.0 38.3 65.1 16.2 111.7 57.4 20.2 72.2 168.0 20.1 16.3 51.6 11.6 15.7 27.4 24.1 11.6 26.8 14.4 22.1 61.7 56.5 23.5 11.4 21.0 23.1 52.7 71.1 48.4 22.6 52.2 40.6 15.4 88.4 25.1 19.3 37.5 19.5 27.0 33.6 25.0 17.9 25.2 30.7 27.2 17.4 15.1 35.1 9.2 22.0 8.8 22.8 11.7 16.0 25.1 15.4 37.8 8.8 25.1 33.4 9.3 14.1 10.6 26.5 14.1 23.2 18.2 11.9 13.3 16.9 13.6 18.8 4.2 9.7 16.2 9.5 21.3 17.3 17.3 14.3 15.8 18.7 18.9 11.3 27.3 5.8 20.9 7.5 17.5 20.1 21.6 15.6 23.6 13.2 8.7 18.9 23.0 7.5 19.6 10.4 6.1 7.8 24.9 12.0 12.7 17.6 9.6 12.3 19.6 10.4 5.9 13.0 13.3 9.7 20.2 8.3 11.5 15.1 12.3 20.7 11.7 11.7 21.1 13.1 18.8 13.7 7.4 24.5 28.4 6.9 24.4 25.1 28.2 30.0 5.7 22.1 33.4 30.8 37.8 25.1 8.8 15.4 20.1 9.3 65.1 111.7 72.2 168.0 61.7 56.5 52.7 71.1 88.4 35.1 VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239330-114291513 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.3" "Group enriched" "Detected in some" 5 "CAPAN-2: 11.3;HaCaT: 5.4;SCLC-21H: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037847 Uncertain "Secreted to extracellular matrix" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" 0.7 0.2 1.5 2.2 1.8 0.4 3.9 1.0 3.2 5.3 2.0 2.1 3.6 2.5 1.4 14.3 5.5 10.8 2.6 0.3 2.2 1.6 1.0 0.3 8.4 0.4 4.1 1.7 2.3 6.0 0.1 4.1 0.6 2.4 7.4 1.1 0.1 16.3 1.6 0.4 6.7 2.1 0.1 2.3 1.6 12.4 2.3 2.2 1.2 0.8 1.3 1.5 2.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.3 0.0 0.4 0.0 5.4 0.0 1.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 1.8 1.0 3.2 2.2 1.6 4.1 1.7 2.4 2.2 WDR13 ENSG00000101940 "WD repeat domain 13" Q9H1Z4 X 48590042-48608867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000913 Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA000913: AB_1858795" "unprognostic (5.03e-2)" "unprognostic (6.53e-3)" "unprognostic (3.65e-3)" "unprognostic (2.10e-3)" "unprognostic (3.50e-1)" "unprognostic (1.54e-3)" "unprognostic (3.54e-2)" "unprognostic (6.76e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.58e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (4.32e-2)" 24.5 30.4 39.9 13.9 36.9 15.7 19.1 14.4 33.9 18.6 25.5 17.6 41.5 23.0 26.0 41.2 23.1 30.8 21.1 49.8 30.2 18.9 24.2 50.2 19.3 11.1 20.0 35.8 35.0 74.7 21.8 24.4 23.9 17.0 19.6 14.4 16.5 30.4 35.8 48.5 21.7 22.0 20.2 17.5 17.4 22.7 11.0 20.5 8.6 21.9 21.1 10.5 17.9 19.7 16.8 21.1 29.2 28.2 17.3 13.8 15.9 14.9 22.0 11.0 34.0 15.2 22.4 8.4 10.4 19.0 12.1 11.1 13.0 24.1 10.4 10.0 21.2 12.9 5.5 22.7 4.3 12.3 9.7 7.1 25.9 23.6 34.6 6.1 19.4 21.1 32.5 17.1 31.5 16.5 7.0 13.3 16.7 21.5 8.4 10.7 7.9 17.3 8.1 11.7 18.8 21.3 11.9 12.8 15.9 11.7 24.5 24.0 15.6 11.9 27.3 12.6 18.7 19.8 9.9 15.5 5.7 3.8 18.6 9.2 17.3 29.2 23.1 12.7 11.9 24.7 9.5 16.8 12.6 11.3 21.1 13.4 10.0 11.4 16.0 17.3 28.2 13.3 13.8 15.9 39.9 36.9 14.4 33.9 30.2 18.9 20.0 35.8 17.0 20.5 WDR6 ENSG00000178252 "WD repeat domain 6" Q9NNW5 3 49007062-49015953 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042622 Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA042622: AB_10966784" "unprognostic (2.41e-2)" "unprognostic (2.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.26e-2)" "unprognostic (4.80e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (2.97e-6)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-3)" "unprognostic (1.94e-2)" "prognostic favourable (4.52e-5)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.61e-2)" 15.8 36.7 21.5 26.1 23.5 14.9 19.7 29.9 29.9 32.7 31.0 30.8 56.4 27.5 39.0 37.0 18.7 33.1 32.6 20.4 20.1 20.4 26.0 22.0 21.1 28.2 22.8 26.9 60.9 46.0 56.7 55.8 24.3 22.1 39.0 22.1 34.3 33.4 54.4 23.9 26.6 28.3 40.8 17.5 29.1 24.7 23.7 22.1 26.9 50.7 20.3 25.1 31.2 24.6 12.3 14.4 10.3 12.9 11.7 18.9 12.0 17.4 24.1 39.9 33.8 26.8 21.9 27.0 26.1 21.6 29.5 24.0 21.4 25.3 28.1 16.7 41.6 20.0 31.8 36.5 21.1 22.3 21.1 26.6 59.1 28.1 27.2 27.4 12.0 39.3 26.3 27.2 20.6 21.5 15.1 30.1 26.7 34.7 31.8 31.3 35.4 22.4 18.7 17.1 17.7 35.0 51.9 19.4 36.4 19.6 16.1 11.3 28.0 22.0 28.7 22.0 35.4 21.3 34.6 53.2 22.7 24.4 29.8 35.2 15.7 3.7 9.1 10.3 16.9 12.9 18.9 12.0 12.5 12.9 11.3 12.3 14.7 10.9 3.4 11.7 6.5 14.4 10.5 12.0 21.5 23.5 29.9 29.9 20.1 20.4 22.8 26.9 22.1 22.1 WDTC1 "ADP, DCAF9, KIAA1037" ENSG00000142784 "WD and tetratricopeptide repeats 1" Q8N5D0 1 27234516-27308633 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028177, HPA028180, HPA028182" Uncertain Supported "Golgi apparatus,Vesicles" Vesicles "Golgi apparatus" "HPA028177: AB_10600419, HPA028180: AB_10601676, HPA028182: AB_10602204" "unprognostic (3.18e-2)" "prognostic favourable (4.51e-4)" "unprognostic (5.69e-2)" "unprognostic (8.28e-2)" "unprognostic (3.31e-2)" "unprognostic (2.00e-3)" "unprognostic (1.25e-2)" "unprognostic (9.44e-2)" "unprognostic (2.44e-1)" "unprognostic (5.45e-3)" "unprognostic (1.41e-3)" "unprognostic (1.73e-1)" "prognostic favourable (8.84e-8)" "unprognostic (1.28e-1)" "unprognostic (9.33e-2)" "unprognostic (3.01e-2)" "unprognostic (2.51e-2)" 14.7 17.5 20.2 11.1 22.0 13.2 12.1 21.8 28.4 15.0 15.3 20.7 14.1 13.3 14.5 9.1 12.4 21.1 11.0 29.1 18.0 15.0 13.6 13.0 14.3 13.3 15.8 16.1 15.8 22.3 49.3 12.3 10.9 19.7 14.3 10.1 29.6 20.6 16.5 51.1 20.9 14.2 12.8 15.1 13.2 15.2 28.3 16.5 21.0 19.4 12.1 14.0 15.0 12.3 1.3 1.5 5.6 0.8 0.8 3.3 1.2 13.0 5.7 9.3 0.9 13.3 11.1 3.9 8.1 13.6 8.7 10.6 1.9 13.1 11.0 9.8 16.0 6.8 8.7 12.3 7.5 15.3 14.9 11.5 6.5 5.2 12.0 5.9 15.6 10.5 20.1 10.8 9.9 11.8 11.7 11.9 9.1 7.2 9.6 14.4 4.4 12.4 4.8 6.9 12.3 10.2 2.9 13.7 11.8 10.5 4.5 9.5 6.7 10.4 10.0 7.1 4.4 10.0 3.9 17.2 9.2 5.4 14.6 11.4 8.5 0.3 0.5 5.6 3.3 0.8 1.3 1.3 0.8 1.4 1.5 0.8 0.6 1.5 4.8 0.8 0.6 1.0 0.9 1.2 20.2 22.0 21.8 28.4 18.0 15.0 15.8 16.1 19.7 16.5 WISP1 "CCN4, WISP-1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "WNT1 inducible signaling pathway protein 1" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HHSteC: 7.9;HSkMC: 44.5;hTEC/SVTERT24-B: 25.4;U-2197: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "olfactory region: 11.9" "Not detected" "Not detected" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavourable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.2 11.0 0.6 7.7 1.6 0.0 2.3 0.6 2.9 14.7 3.9 1.0 0.0 1.2 18.5 6.4 2.2 6.5 8.5 4.0 0.7 0.3 18.0 2.9 8.9 13.4 0.8 0.4 13.0 1.0 0.2 2.7 3.5 1.2 3.4 0.9 4.5 1.3 4.2 2.0 1.6 3.9 14.4 6.2 14.6 3.8 3.7 0.4 0.3 1.3 2.7 4.2 14.4 4.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.0 1.7 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 44.5 0.0 25.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.9 0.3 24.3 0.0 0.0 0.0 0.0 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 1.6 0.6 2.9 0.7 0.3 0.8 0.4 1.2 0.4 WISP2 "CCN5, CT58, CTGF-L" ENSG00000064205 "WNT1 inducible signaling pathway protein 2" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 109.7" "Cell line enhanced" "Detected in some" "ASC diff: 9.8;ASC TERT1: 26.3;HeLa: 14.7;HSkMC: 10.6;U-2197: 83.9" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB019273 Approved "Secreted to extracellular matrix" 400000 "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 57.0 6.5 0.2 2.0 2.2 0.4 32.7 0.1 0.5 109.7 4.7 0.6 8.6 0.6 7.0 12.4 47.1 5.5 8.4 29.7 0.3 0.0 0.5 0.9 25.6 0.9 0.1 1.4 48.4 1.8 0.7 0.0 0.9 0.2 20.1 0.9 0.5 4.3 8.9 18.0 30.6 1.4 22.0 0.2 0.5 1.4 37.7 0.4 0.0 2.5 3.7 0.6 18.2 18.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 9.8 26.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.0 0.0 83.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.2 0.1 0.5 0.3 0.0 0.1 1.4 0.2 0.4 WISP3 CCN6 ENSG00000112761 "WNT1 inducible signaling pathway protein 3" O95389 6 112054072-112070969 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 9.5" "Cell line enhanced" "Detected in some" "RT4: 10.9;THP-1: 3.5;U-2197: 2.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 2.3;cerebellum: 5.9" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA062438, HPA078340" Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Endoplasmic reticulum" "HPA062438: , HPA078340: " "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" 0.4 0.5 0.3 0.4 2.3 0.8 4.2 5.9 0.5 1.9 0.3 0.3 0.3 0.1 0.6 9.5 0.9 3.2 1.4 0.4 0.3 0.5 5.3 0.8 0.4 0.5 0.4 0.3 1.6 0.3 0.0 0.3 0.4 0.3 1.1 0.0 0.3 0.6 0.3 0.6 4.8 0.3 0.3 0.4 0.4 0.4 5.8 0.9 0.3 0.3 2.8 2.2 0.3 1.5 1.1 0.6 2.0 0.5 1.7 1.2 0.2 0.1 0.0 0.3 1.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.1 0.3 0.3 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 0.2 0.9 0.4 0.2 0.3 0.1 0.3 0.0 10.9 0.5 0.5 0.1 0.2 0.9 0.2 3.5 0.2 0.2 0.2 2.6 0.3 0.3 0.0 0.3 0.4 1.1 0.2 1.4 0.4 0.6 0.5 0.3 0.6 0.8 0.9 0.9 0.3 1.1 1.2 1.1 2.0 1.7 0.5 0.6 0.6 0.2 0.3 2.3 5.9 0.5 0.3 0.5 0.4 0.3 0.3 0.9 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344272-1400378 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350, HPA061603" Approved Supported Nucleoplasm,Nucleoli,Cytosol 160000000 Cytosol "Nucleoplasm, Nucleoli" "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336, HPA061603: " "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favourable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 55.2 54.3 107.5 35.3 87.1 32.7 37.3 71.5 118.4 28.4 40.2 60.9 23.8 40.2 35.9 54.1 43.1 44.2 23.4 57.7 92.3 81.9 64.5 50.9 32.8 25.4 94.1 77.9 40.2 40.2 41.0 37.9 45.1 73.7 35.0 42.5 27.9 42.4 27.7 135.9 36.8 36.2 32.2 101.1 26.2 38.5 46.0 53.6 30.9 47.5 36.5 37.2 31.6 32.1 19.2 41.5 17.2 36.2 15.0 23.3 31.5 77.8 58.2 70.5 59.3 31.2 36.1 67.8 50.4 29.7 45.0 34.9 104.0 32.0 52.9 59.2 41.7 54.1 59.7 50.9 63.8 36.5 111.3 36.9 48.6 44.5 37.3 35.3 37.8 32.7 37.6 45.0 69.0 54.1 42.3 38.2 57.8 37.9 46.7 28.2 64.6 37.8 56.8 33.3 37.5 45.8 45.1 39.3 59.7 60.6 24.9 39.4 47.2 32.7 51.1 43.7 37.1 55.1 88.9 24.0 44.3 44.4 52.4 42.3 63.1 17.2 31.8 8.6 12.4 36.2 15.6 19.2 18.7 13.9 41.5 16.1 17.0 14.3 10.8 15.0 30.9 28.8 23.3 31.5 107.5 87.1 71.5 90.2 92.3 81.9 94.1 77.9 73.7 53.6 YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916525-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB005065, HPA061603" Approved Approved Nucleoplasm,Nucleoli,Cytosol 760000000 Cytosol "Nucleoplasm, Nucleoli" "CAB005065: AB_2218378, HPA061603: " "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavourable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavourable (2.28e-5)" "prognostic unfavourable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavourable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavourable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" 54.6 40.9 89.9 51.8 104.6 70.8 39.6 55.8 117.7 52.4 69.6 38.7 25.3 47.4 43.5 37.6 141.8 38.3 51.9 29.1 81.7 67.0 44.1 32.9 40.7 60.0 50.1 66.7 46.4 27.5 37.8 25.2 69.0 78.2 42.5 70.3 31.7 55.2 47.2 19.7 63.0 71.4 53.5 43.8 56.3 51.5 34.1 31.5 89.4 46.0 74.9 83.2 53.6 70.2 58.6 57.2 129.4 77.9 57.0 78.4 104.9 138.9 67.6 129.0 37.0 32.1 40.8 63.9 65.3 85.0 88.5 86.2 47.0 91.2 62.5 70.9 103.7 60.5 81.1 93.1 134.8 55.3 32.0 59.0 51.2 30.4 42.3 24.6 67.7 37.8 126.9 73.1 116.5 79.4 67.0 61.3 75.6 50.5 101.6 43.7 43.6 70.9 43.3 37.6 42.9 85.1 78.5 72.2 51.5 49.7 49.3 103.4 71.4 29.1 64.6 44.9 65.9 54.1 58.5 39.1 46.4 76.7 74.3 46.5 183.7 129.4 45.0 81.2 69.1 66.5 70.3 58.6 59.0 66.5 57.2 48.0 44.8 56.4 74.6 57.0 77.9 35.4 78.4 104.9 89.9 104.6 55.8 117.7 81.7 67.0 50.1 66.7 78.2 31.5 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 212.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 212.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 59.0 22.4 40.2 42.4 35.0 14.2 89.9 16.3 31.0 91.5 60.2 49.6 24.8 26.0 90.6 37.5 66.8 59.9 36.5 36.2 45.1 15.3 34.6 46.0 45.6 39.0 32.7 16.7 121.7 47.1 63.4 14.8 62.7 44.9 65.3 21.9 29.9 60.3 43.7 31.6 90.2 28.5 91.2 47.3 33.9 42.2 26.9 39.4 22.1 43.3 22.7 57.1 81.2 93.2 37.0 8.7 212.7 17.7 10.4 16.1 14.4 38.8 37.3 15.5 22.4 39.3 31.6 34.3 16.5 27.4 9.6 12.1 16.3 25.8 9.4 10.0 28.4 18.0 1.4 51.0 11.8 4.4 2.2 3.4 18.7 11.5 22.4 0.5 4.3 26.6 65.5 11.7 76.7 19.3 9.6 18.5 51.1 9.2 1.4 1.7 12.9 5.4 24.9 20.8 2.8 35.3 28.0 0.1 0.4 18.6 26.8 13.8 24.6 0.4 44.1 28.6 21.0 22.6 15.7 10.4 5.2 6.5 35.5 0.2 10.8 14.2 17.7 0.2 16.1 17.2 15.0 19.7 12.9 11.2 8.7 37.0 14.1 12.4 212.7 10.4 11.4 1.1 12.0 14.4 40.2 35.0 16.3 31.0 45.1 15.3 32.7 16.7 44.9 39.4 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491123 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 64.8;skeletal muscle: 111.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 48.5" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "HPA054267: " "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 14.9 5.4 8.8 6.6 10.4 9.0 10.3 6.3 9.1 7.1 7.8 4.5 4.5 3.9 7.4 6.3 12.7 5.4 6.1 64.8 9.2 6.3 6.4 3.7 7.8 6.0 7.6 6.4 6.6 4.4 8.4 7.1 5.0 11.9 7.8 5.6 11.3 6.0 5.7 111.1 4.3 5.9 10.9 8.0 6.3 6.0 5.7 7.2 3.4 5.7 46.9 6.8 7.0 17.7 8.3 10.8 48.5 19.6 3.9 5.1 4.5 14.1 8.2 14.4 15.9 36.4 32.1 8.8 11.5 11.0 10.1 10.8 19.3 4.1 9.5 10.3 14.1 16.2 14.9 11.8 15.5 15.4 7.2 18.2 19.2 6.9 10.5 21.8 10.9 24.1 7.9 15.3 17.1 16.2 21.6 1.3 16.4 5.6 8.3 5.3 6.1 8.4 8.0 26.2 5.2 5.3 16.0 9.2 4.9 23.3 11.0 13.0 10.1 14.2 24.4 10.9 16.8 14.4 16.8 7.9 15.2 35.6 9.7 17.4 18.8 19.9 19.6 7.6 5.1 15.9 4.5 6.7 4.2 4.2 10.5 8.3 3.8 3.4 48.5 3.9 18.5 10.8 3.8 4.5 8.8 10.4 6.3 9.1 9.2 6.3 7.6 6.4 11.9 7.2 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544032-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.0" "Cell line enhanced" "Detected in some" "AF22: 11.0;BJ hTERT+: 9.6;HAP1: 14.1;LHCN-M2: 12.4;RH-30: 20.5;T-47d: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 16 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 16 "dendritic cells: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000001, HPA065701, CAB065764" Enhanced Approved Mitochondria Mitochondria "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA065701: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favourable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favourable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 10.1 1.2 0.9 1.6 0.9 0.1 10.7 0.4 1.6 34.4 1.9 2.4 25.4 0.2 20.5 20.5 2.2 17.5 4.3 5.7 0.9 1.5 6.3 49.0 1.5 0.2 1.2 0.7 14.4 1.0 0.1 2.3 0.3 1.9 28.0 0.5 3.8 1.6 36.1 8.1 3.9 1.1 7.6 1.9 0.9 1.6 9.3 1.2 5.4 3.1 2.0 1.2 6.3 13.1 0.0 5.4 0.3 0.0 0.1 0.0 0.1 0.0 4.6 11.0 0.0 0.0 0.1 0.0 5.8 9.6 0.4 0.1 0.2 0.0 0.0 0.0 0.7 0.0 14.1 0.0 0.1 0.0 1.8 0.0 1.1 0.0 0.6 0.0 0.0 4.5 0.0 1.6 0.0 3.4 4.0 1.8 12.4 1.2 0.0 0.0 4.4 0.0 0.0 20.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 8.6 5.2 0.2 0.2 2.0 0.1 2.9 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 5.4 0.0 0.1 0.9 0.9 0.4 1.6 0.9 1.5 1.2 0.7 1.9 1.2 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446034-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 32.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 15.4;LHCN-M2: 26.1;TIME: 27.7;U-87 MG: 34.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 3.2;myeloid DC: 2.9;naive B-cell: 2.6" "Group enriched" "Detected in many" 29 "B-cells: 2.6;dendritic cells: 2.9;monocytes: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: , HPA064439: " "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavourable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 3.1 10.2 6.7 12.5 3.0 2.0 7.3 12.2 1.8 2.7 32.3 1.0 1.7 2.1 1.9 1.6 2.2 4.4 3.3 12.5 9.6 1.2 0.8 2.9 6.0 18.3 6.6 7.7 1.5 2.7 1.8 2.2 24.6 3.2 2.8 1.6 3.4 3.2 3.9 3.4 2.5 3.4 27.3 6.2 2.3 4.6 18.4 2.0 6.0 0.4 5.4 3.1 1.9 2.6 2.9 0.0 3.2 0.0 0.0 0.9 2.5 0.5 0.1 0.0 2.2 8.8 1.7 13.5 6.2 1.2 1.7 2.7 0.3 0.0 0.5 5.2 4.9 0.1 4.5 2.2 0.2 4.6 7.1 0.0 0.0 1.1 0.8 0.8 2.1 4.6 15.4 1.2 8.4 6.7 1.3 26.1 0.1 0.1 0.0 2.9 0.2 0.0 0.0 3.2 2.6 0.2 0.4 2.7 0.6 0.0 0.2 0.1 0.1 27.7 12.7 0.2 1.6 9.4 0.0 0.0 0.0 34.4 0.1 2.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 10.2 12.5 7.3 9.2 12.5 9.6 18.3 6.6 24.6 18.4 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767664-6780280 "Cancer-related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 20.7;HeLa: 13.5;hTERT-HME1: 12.2;RT4: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "NK-cell: 2.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" 24353 Vesicles "CAB078457: AB_2532532, HPA058610: " "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 11.1 1.1 1.6 10.5 3.1 0.6 5.3 1.8 7.5 3.7 13.1 2.6 1.9 4.2 3.4 6.7 3.7 3.7 15.6 3.9 2.4 1.6 3.6 3.8 12.8 1.3 2.9 1.3 3.1 9.2 4.7 2.3 7.6 2.7 8.8 9.5 18.3 2.0 1.2 2.6 9.1 13.4 3.4 1.4 8.0 13.8 1.1 2.7 0.3 13.2 6.2 3.1 14.1 9.1 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.5 2.3 0.0 0.0 20.7 0.0 0.0 0.3 0.7 6.9 4.1 1.8 0.0 0.0 3.7 0.0 13.5 0.0 1.0 0.0 0.5 0.1 6.3 0.0 12.2 4.2 0.0 0.0 0.1 0.0 0.0 3.9 0.5 0.5 4.0 0.0 0.3 1.5 16.5 0.7 1.0 4.9 0.0 0.0 0.0 4.3 1.0 1.2 1.8 0.0 0.5 0.2 0.5 0.0 2.1 1.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 1.6 3.1 1.8 3.3 2.4 1.6 2.9 1.3 2.7 2.7 BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753645-55875564 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7;prostate: 29.4;retina: 21.2" "Group enriched" "Detected in some" 11 "AF22: 22.1;U-2 OS: 17.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons and medulla: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" 2.1 0.6 0.2 3.3 0.2 0.1 1.5 0.7 0.7 0.2 4.3 0.0 0.0 5.0 0.1 0.2 1.9 0.2 1.5 3.4 0.3 0.2 1.6 1.9 14.3 0.2 2.0 1.4 0.2 1.2 0.1 5.0 42.7 5.2 29.4 4.7 21.2 1.7 0.0 7.0 0.2 10.2 5.5 3.6 0.1 1.9 0.2 0.0 0.0 1.5 5.0 0.1 11.8 1.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.7 0.3 0.2 2.0 1.4 5.2 0.0 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823933 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 122.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "T-reg: 6.8" "Group enriched" "Detected in many" 5 "NK-cells: 1.7;T-cells: 6.8" "Low region specificity" "Detected in single" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavourable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavourable (9.17e-5)" "prognostic unfavourable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavourable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 3.2 1.5 1.3 18.6 1.7 21.6 1.8 5.1 1.2 2.5 6.3 1.0 0.8 6.6 2.2 2.1 11.7 1.7 2.4 3.2 1.8 1.8 1.7 1.6 3.4 15.6 1.6 0.8 4.5 0.9 0.5 3.2 12.0 1.3 2.2 7.8 1.0 2.1 0.8 1.1 4.2 7.4 2.4 1.8 8.9 2.9 8.4 0.8 122.3 1.4 18.8 18.4 2.5 5.1 0.3 0.9 0.6 0.3 1.7 6.8 1.9 38.1 9.9 27.3 11.6 1.4 3.8 22.3 26.6 11.7 35.5 26.4 21.6 23.7 35.1 7.2 14.0 12.9 34.3 15.7 29.2 16.8 15.8 28.2 13.2 21.0 0.3 42.4 20.0 0.9 1.2 14.6 8.8 21.2 40.0 35.3 28.1 13.7 54.0 24.6 21.5 11.1 24.8 52.8 17.1 10.0 7.6 11.6 12.3 14.0 17.1 7.4 14.3 18.0 12.4 16.6 25.2 17.5 25.4 22.4 23.7 40.2 9.5 43.2 18.4 0.0 0.3 0.6 0.2 0.1 0.1 0.3 2.0 1.4 0.9 0.1 0.0 0.5 0.3 1.7 0.3 0.1 6.8 1.9 1.3 1.7 5.1 1.2 1.8 1.8 1.6 0.8 1.3 0.8 CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68722616 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease mutation, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;retina: 40.5" "Cell line enhanced" "Detected in some" "A-431: 24.4;HaCaT: 67.7;HBEC3-KT: 32.6;hTCEpi: 26.1;hTERT-HME1: 19.9;RPTEC TERT1: 29.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 10 "pons and medulla: 16.0" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavourable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavourable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" 2.2 0.1 1.0 2.5 1.2 0.0 8.7 1.5 1.1 10.5 1.0 2.2 3.0 0.3 9.4 10.3 23.5 8.9 1.4 0.4 1.1 0.8 8.3 0.2 3.6 2.1 0.6 0.4 32.6 0.4 0.5 3.6 6.4 16.0 11.7 0.5 40.5 9.3 4.4 0.1 21.2 0.4 4.1 1.5 10.0 0.7 2.2 0.1 44.0 2.0 26.1 20.1 2.5 6.7 0.9 0.6 1.4 0.5 0.6 0.8 0.2 24.4 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 14.6 9.1 0.0 0.1 0.0 67.7 0.6 32.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 26.1 0.0 19.9 0.0 0.0 0.0 0.0 12.7 0.0 0.0 1.2 2.0 0.0 0.0 0.0 29.3 11.0 0.1 0.0 0.2 0.0 11.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.5 0.2 0.4 0.2 0.3 0.6 0.5 0.4 0.1 0.9 0.6 0.8 1.4 0.6 0.2 0.6 0.2 0.2 1.0 1.2 1.5 1.1 1.1 0.8 0.6 0.4 16.0 0.1 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194758-65211488 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 7.1;ASC TERT1: 4.3;EFO-21: 1.8;HSkMC: 10.9" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003195 Uncertain "Secreted to extracellular matrix" 11000000 "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavourable (2.24e-5)" "unprognostic (4.68e-3)" 32.0 0.4 0.0 8.1 0.1 0.0 17.0 0.4 0.0 39.9 11.1 0.1 12.7 1.2 9.2 44.7 21.4 10.5 19.6 16.5 0.0 0.0 0.5 1.0 1.8 1.4 0.2 0.0 9.6 2.4 0.1 0.4 3.0 0.1 13.3 3.9 0.6 5.6 5.1 19.7 8.4 12.5 41.6 0.3 0.3 5.4 18.4 0.0 1.4 2.0 23.4 3.1 41.4 17.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 7.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 10.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207603431 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavourable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 21.2 12.9 19.4 24.8 17.0 22.9 16.7 25.5 18.7 17.6 15.7 14.3 14.7 12.6 19.3 14.9 17.9 15.4 15.5 14.4 15.4 14.5 14.6 13.1 17.7 21.7 15.8 17.7 20.5 12.9 19.8 20.0 19.8 16.1 16.3 16.2 11.2 16.2 14.9 11.6 14.3 15.2 19.5 19.8 19.0 13.3 39.2 18.5 38.4 19.7 13.3 27.7 16.1 23.6 22.1 20.7 34.8 19.1 28.4 22.5 14.5 15.4 13.8 25.7 9.8 15.1 15.5 14.6 9.9 14.9 17.3 18.2 14.0 15.7 10.0 13.4 14.6 13.5 23.2 13.6 25.5 16.0 8.4 18.4 12.4 14.3 12.6 17.3 13.5 11.1 10.1 14.3 21.3 24.3 12.9 14.7 21.3 10.6 26.4 10.3 18.3 8.4 20.6 14.0 13.2 15.4 16.0 17.7 15.4 13.8 10.1 11.9 11.3 19.0 11.6 14.1 15.1 14.8 12.7 13.3 16.8 23.1 17.4 16.0 14.8 16.9 17.0 16.8 17.3 18.0 15.4 22.1 16.6 16.7 20.7 20.2 19.9 13.5 34.8 28.4 19.1 11.3 22.5 14.5 19.4 17.0 25.5 18.7 15.4 14.5 15.8 17.7 16.1 18.5 CTGF "CCN2, IGFBP8" ENSG00000118523 "Connective tissue growth factor" P29279 6 131948176-131951373 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 128.3;HUVEC TERT2: 107.9;TIME: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 11 "naive B-cell: 11.6" "Lineage enriched" "Detected in single" 117 "B-cells: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" 5200000 "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavourable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 51.9 15.5 3.5 48.2 7.6 0.0 39.2 1.6 7.1 84.0 26.9 7.2 27.5 5.8 84.9 50.1 38.9 56.3 82.5 73.6 8.8 3.6 83.5 18.8 45.8 53.3 4.7 9.4 30.7 26.3 4.7 9.7 44.0 13.8 54.5 19.7 55.0 28.2 45.3 29.4 30.1 28.7 123.4 12.0 169.8 41.6 24.4 2.3 5.9 66.9 46.9 9.8 48.5 23.3 11.6 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 10.0 0.2 22.7 12.9 0.1 29.0 13.9 18.0 9.6 0.0 0.9 0.0 128.3 37.2 0.4 0.3 2.0 17.0 0.1 0.2 0.0 4.1 10.4 8.9 0.0 0.0 18.8 0.4 13.0 3.2 107.9 0.0 0.0 51.0 0.1 0.0 0.0 4.8 1.7 2.4 0.4 0.0 6.5 0.0 0.0 0.0 2.9 4.9 1.3 0.4 0.2 222.6 25.0 19.5 31.4 53.4 0.9 0.1 0.2 3.4 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.5 7.6 1.6 7.1 8.8 3.6 4.7 9.4 13.8 2.3 CTLA4 "CD, CD152, CELIAC3, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867786-203873960 "CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease mutation, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 31.2" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.8;U-266/70: 5.8;U-266/84: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in some" 6 "T-reg: 24.8" "Lineage enriched" "Detected in single" 248 "T-cells: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favourable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" 1.6 0.2 0.2 24.1 0.3 2.9 1.3 0.2 0.6 0.8 1.6 0.1 0.6 0.2 1.1 0.1 2.0 1.2 3.6 0.5 0.3 0.5 1.6 0.6 5.8 27.9 0.3 0.3 0.7 0.3 0.1 0.6 0.1 1.7 1.1 1.7 0.8 1.4 0.6 0.2 1.0 10.3 0.3 1.5 6.7 1.2 1.7 0.1 14.2 1.9 3.3 31.2 4.6 1.3 0.0 0.0 0.0 0.0 0.0 24.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.0 0.5 0.0 0.3 0.0 5.8 16.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 24.8 0.4 0.2 0.3 0.2 0.6 0.3 0.5 0.3 0.3 1.7 0.1 CYR61 "CCN1, GIG1, IGFBP10" ENSG00000142871 "Cysteine rich angiogenic inducer 61" O00622 1 85580761-85583962 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 98.6;U-138 MG: 98.8;U-251 MG: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavourable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 79.6 23.6 3.5 106.4 6.4 0.0 47.8 0.8 4.8 110.6 27.4 13.1 20.3 3.0 73.4 64.4 26.3 76.5 108.4 60.1 4.7 4.0 30.8 41.7 98.8 59.9 2.9 4.4 66.8 17.2 5.1 8.8 64.7 7.2 60.8 16.5 23.6 14.6 49.3 55.3 28.2 15.6 102.4 6.1 58.9 35.0 26.6 3.7 1.9 56.4 23.6 16.3 101.6 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 2.2 6.3 1.3 41.4 38.4 9.5 67.8 50.9 98.6 75.6 16.3 2.4 0.0 43.4 66.8 4.5 6.4 16.2 82.0 0.1 0.8 0.0 10.3 2.3 63.8 0.4 0.0 20.8 10.6 44.5 30.1 73.4 0.1 0.0 51.2 2.0 0.0 0.1 4.1 4.3 0.0 18.8 0.0 75.2 2.7 0.0 0.4 76.0 15.4 10.3 5.0 0.3 79.0 98.8 30.8 14.1 95.5 0.0 0.1 0.1 1.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 6.4 0.8 4.8 4.7 4.0 2.9 4.4 7.2 3.7 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475597-54651171 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 41.3" "Cell line enhanced" "Detected in some" "AF22: 19.3;ASC diff: 7.9;hTEC/SVTERT24-B: 8.1;U-138 MG: 30.5" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" "Focal adhesion sites" "HPA054460: , HPA065235: " "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavourable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 3.5 2.7 15.5 2.3 11.0 0.6 2.0 1.4 14.8 1.8 1.3 6.6 0.4 1.0 2.1 1.0 2.4 13.6 10.6 18.1 11.0 12.5 3.6 3.2 1.0 1.2 8.4 6.2 2.4 1.9 0.9 1.2 2.4 7.3 1.6 1.4 7.6 1.7 1.5 41.3 0.6 1.1 3.5 5.4 0.9 0.9 2.2 6.4 0.0 5.9 6.4 1.0 3.6 3.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 19.3 0.0 7.9 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 2.6 0.0 8.1 0.0 1.0 0.0 2.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.0 4.1 0.0 5.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 30.5 1.9 0.8 0.0 0.0 0.0 0.1 1.3 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 11.0 1.4 12.6 11.0 12.5 8.4 6.2 7.3 6.4 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell line enhanced" "Detected in some" "MCF7: 6.1;SH-SY5Y: 5.4;U-251 MG: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favourable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.1 0.4 1.2 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 1.8 0.0 6.1 0.0 0.4 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.4 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.8 3.2 7.1 4.6 13.0 9.1 11.3 7.0 9.0 5.0 7.4 7.2 3.5 37.3 4.2 4.7 4.4 5.1 3.9 7.3 13.1 3.3 4.0 3.3 7.4 8.1 4.9 9.5 3.4 6.3 4.6 10.0 5.3 2.3 13.4 3.8 5.4 4.6 4.0 5.2 3.7 18.1 9.8 6.7 6.2 9.2 5.5 7.5 4.1 10.7 7.0 3.9 2.9 4.2 4.3 4.6 9.7 4.3 25.2 12.6 26.4 6.1 4.5 5.7 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977864-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 31.4;thyroid gland: 14.8" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 54.2;TIME: 101.3" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "MAIT T-cell: 1.6;memory CD4 T-cell: 2.7;memory CD8 T-cell: 1.7;naive CD8 T-cell: 1.6;NK-cell: 3.7" "Group enriched" "Detected in many" 32 "NK-cells: 3.7;T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" 1539000 400000 "unprognostic (4.70e-2)" "prognostic unfavourable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavourable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" 1.5 3.5 0.3 0.4 0.6 0.2 0.6 0.2 0.7 1.5 1.1 0.8 4.2 0.3 3.0 1.1 0.3 0.2 0.9 2.4 0.9 3.7 31.4 2.2 12.9 0.9 0.5 0.3 2.3 1.8 1.7 9.0 0.5 1.3 4.8 0.0 1.5 5.6 3.2 0.7 0.3 2.4 0.4 1.1 4.0 0.5 0.6 0.5 0.6 14.8 0.8 0.4 1.4 1.0 0.0 0.0 0.0 0.0 3.7 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 1.7 0.7 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 54.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 101.3 0.8 2.4 7.0 3.7 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.6 0.0 2.7 1.7 0.0 0.0 0.0 1.6 0.0 3.7 0.0 0.0 0.0 0.5 0.3 0.6 0.2 0.7 0.9 3.7 0.5 0.3 1.3 0.5 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408306-48645849 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 69.8" "Cell line enhanced" "Detected in many" "ASC diff: 36.6;ASC TERT1: 79.0;fHDF/TERT166: 67.8;HSkMC: 42.7;U-138 MG: 34.8;U-2197: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" 540000000 Cytosol "CAB002670: , CAB058696: , CAB068188: , HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavourable (7.44e-5)" "prognostic unfavourable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavourable (5.11e-4)" 34.2 5.4 2.1 7.8 2.7 1.8 10.9 1.0 2.8 24.6 11.1 3.5 10.7 2.2 18.4 25.6 22.1 12.1 15.5 24.3 2.5 2.3 2.9 1.9 10.7 5.8 2.8 2.6 20.4 2.5 2.6 3.3 69.8 3.1 11.8 6.9 13.4 5.7 7.8 15.4 6.6 6.9 21.5 3.8 11.3 7.2 13.6 1.6 1.9 17.9 16.3 4.9 22.8 11.2 0.8 0.8 1.8 0.6 1.1 0.6 0.2 0.0 0.8 3.3 3.7 36.6 79.0 0.0 28.5 10.3 8.5 5.4 0.0 0.0 0.0 1.3 67.8 0.1 0.6 0.1 7.7 3.2 0.2 0.3 14.5 0.0 20.6 0.1 0.0 42.7 0.0 22.5 2.6 9.1 0.0 0.0 9.1 0.0 0.2 0.0 0.6 1.1 0.0 2.8 0.0 1.0 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.2 17.2 34.8 1.0 50.5 6.0 0.2 0.1 0.0 23.3 0.0 2.2 1.1 0.5 0.7 0.5 0.3 0.4 0.5 0.4 0.4 0.2 0.8 0.5 0.6 1.8 1.1 0.6 0.8 0.3 0.2 2.1 2.7 1.0 2.8 2.5 2.3 2.8 2.6 3.1 1.6 GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814013 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 68.8" "Cell line enhanced" "Detected in some" "HeLa: 3.8;MCF7: 6.0;SK-BR-3: 5.2;U-87 MG: 6.0" "Cancer enhanced" "Detected in many" "liver cancer: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 0.9" "Low region specificity" "Detected in all" HPA071228 Approved "Golgi apparatus" "Golgi apparatus" "HPA071228: " "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" 0.2 3.9 0.1 0.6 0.3 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 11.4 68.8 0.1 0.1 0.1 0.1 0.1 0.5 3.9 0.1 0.1 0.5 0.2 0.0 1.4 0.3 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.6 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.8 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.5 0.0 5.2 0.0 0.0 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.1 0.1 0.5 0.1 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918838 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 994.5" "Cell line enriched" "Detected in some" 5 "U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.1;T-reg: 2.2" "Group enriched" "Detected in many" 4 "B-cells: 2.1;T-cells: 2.2" HPA043715 Supported "Secreted to blood" 1735000 180000 "HPA043715: " "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 0.3 0.0 0.0 0.5 0.0 1.1 0.2 0.1 0.1 0.4 0.4 0.0 0.0 3.3 1.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.0 0.0 0.0 0.3 994.5 217.7 0.1 0.2 0.5 0.0 0.1 0.2 0.8 0.9 0.4 0.1 0.0 1.6 0.3 0.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.0 0.5 0.0 2.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.5 7.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.5 0.0 2.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 GHRH GHRF ENSG00000118702 "Growth hormone releasing hormone" P01286 20 37251082-37261835 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 37.3" "Group enriched" "Detected in some" 7 "NTERA-2: 3.5;U-266/84: 12.4" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 8.5" "Region enriched" "Detected in some" 15 "hypothalamus: 37.3" "Cell type enhanced" "Detected in single" "eosinophil: 2.7" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in some" 9 "hypothalamus: 38.7" "Low region specificity" "Detected in many" "Secreted in other tissues" "unprognostic (4.78e-2)" "unprognostic (2.57e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-1)" 0.1 2.7 0.3 0.1 2.4 0.0 0.6 0.1 1.0 0.1 4.0 0.1 0.1 8.1 0.1 0.1 0.7 0.0 0.1 6.5 0.1 37.3 0.1 0.1 0.1 0.1 0.1 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 7.7 0.1 0.1 0.1 1.9 0.1 0.1 7.5 0.4 0.1 0.1 0.1 0.1 0.0 0.7 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.4 0.1 1.0 0.1 37.3 0.1 0.8 0.1 0.1 GIGYF2 "GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15" ENSG00000204120 "GRB10 interacting GYF protein 2" Q6Y7W6 2 232697299-232860575 "Disease related genes, Predicted intracellular proteins" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050899, HPA054612, HPA059918, HPA065064" Approved Enhanced Cytosol Cytosol "HPA050899: , HPA054612: , HPA059918: , HPA065064: " "unprognostic (7.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (8.61e-2)" "unprognostic (8.39e-3)" "unprognostic (2.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.27e-2)" "unprognostic (7.40e-3)" "unprognostic (8.01e-2)" "prognostic favourable (6.97e-5)" "unprognostic (7.53e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.66e-1)" 22.8 22.1 20.7 16.5 19.4 15.2 19.7 33.0 21.7 17.9 17.5 25.0 21.2 15.9 23.7 15.0 18.6 17.8 13.7 21.3 19.2 15.7 23.1 13.7 15.7 15.4 21.4 15.6 24.6 26.5 47.5 38.1 18.1 21.5 19.4 16.9 18.1 21.4 21.7 41.5 23.4 17.2 22.3 27.5 18.9 18.2 53.4 22.0 19.2 22.4 17.7 17.3 20.8 20.5 10.1 9.8 21.5 14.6 9.8 9.9 5.2 15.9 15.4 18.0 18.6 24.5 23.6 20.1 20.1 17.3 14.8 15.9 14.4 13.3 9.6 5.4 15.0 16.9 21.5 16.2 18.2 22.3 16.0 35.3 15.9 21.7 15.4 28.6 22.6 14.8 16.7 17.8 25.4 16.5 32.9 10.6 16.9 16.9 18.7 10.2 18.3 11.4 19.0 35.6 13.1 13.8 24.5 16.0 13.3 20.3 14.8 15.6 14.3 19.9 23.9 15.7 13.3 17.6 15.5 21.7 14.5 18.9 14.2 16.8 15.2 21.5 8.6 10.8 7.9 6.7 9.9 5.6 6.5 7.2 9.8 10.1 7.8 5.9 11.2 9.8 14.6 7.6 9.6 5.2 20.7 19.4 33.0 21.7 19.2 15.7 21.4 15.6 21.5 22.0 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74833981-74893359 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 26.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028587 Enhanced "HPA028587: AB_10602605" "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavourable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 27.0 2.2 4.4 9.5 5.0 20.4 10.8 0.7 4.5 5.3 23.2 7.3 5.7 1.3 2.6 40.1 13.6 4.8 9.1 8.3 2.8 2.3 2.1 1.4 16.5 5.0 8.5 1.1 14.9 3.5 1.1 1.7 13.2 5.4 4.0 19.2 9.6 10.3 0.5 29.3 9.7 8.9 1.7 10.9 7.4 8.7 24.8 7.4 4.3 7.1 22.3 9.2 29.0 8.3 0.8 6.2 26.2 7.1 0.0 0.8 2.0 16.2 0.1 3.8 13.7 32.3 3.4 14.0 6.3 9.2 7.1 10.3 13.0 2.9 11.8 6.1 2.9 5.6 17.2 13.3 20.8 3.3 3.7 16.0 3.7 17.8 10.2 23.3 26.3 5.6 14.5 13.6 23.8 3.4 13.9 0.0 2.0 11.5 5.6 23.9 13.6 11.3 9.2 7.9 9.2 4.3 22.9 2.7 13.4 4.0 20.4 8.0 1.0 3.7 2.7 22.8 4.0 9.4 11.4 8.1 2.3 5.9 53.2 17.1 5.8 6.6 7.1 26.2 0.1 5.7 0.3 0.6 0.4 0.1 6.2 0.8 0.7 0.7 5.9 0.0 3.7 0.1 0.8 2.0 4.4 5.0 0.7 4.5 2.8 2.3 8.5 1.1 5.4 7.4 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269765-8307111 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.9" "Cell line enriched" "Detected in some" 5 "U-2197: 62.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 9 "basal ganglia: 8.2" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in female reproductive system" Vesicles "HPA021187: AB_1851311, HPA063810: " "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavourable (1.29e-4)" "unprognostic (1.34e-2)" 23.7 1.8 0.6 7.3 8.2 5.3 35.6 0.7 0.9 12.3 9.4 0.8 5.4 3.7 19.6 26.6 14.4 7.9 19.8 57.9 0.7 0.3 1.7 1.6 15.4 4.3 0.8 0.9 30.7 2.8 0.0 5.1 9.6 0.9 15.4 2.0 8.6 6.6 3.0 12.9 9.0 6.7 50.1 0.8 1.8 6.8 7.2 0.6 1.3 9.3 11.6 3.0 28.7 12.7 0.0 0.4 1.3 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 2.0 3.8 0.1 0.8 0.0 0.9 0.2 0.0 0.0 0.0 4.7 2.1 0.0 0.4 0.0 0.3 0.0 0.7 0.4 4.9 0.0 2.1 0.0 0.2 0.4 0.0 1.4 0.0 3.3 0.1 0.0 3.5 0.0 0.0 12.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 5.5 0.1 8.9 0.1 0.0 0.0 0.3 2.7 0.5 1.6 62.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.1 0.6 8.2 0.7 0.9 0.7 0.3 0.8 0.9 0.9 0.6 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267079-162318703 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.5;BJ hTERT+ SV40 Large T+ RasG12V: 39.2;Karpas-707: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002656 Approved "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 17.2 11.3 5.8 23.1 5.8 26.9 10.5 2.8 6.4 10.3 12.5 4.9 9.5 12.3 7.3 11.0 9.9 8.3 10.8 6.3 6.1 4.7 10.4 11.8 19.7 17.2 6.1 3.2 11.2 11.5 11.6 14.0 15.6 7.0 12.3 7.8 5.9 15.7 17.2 4.7 6.4 18.0 5.8 7.4 25.3 9.0 4.3 4.2 20.5 15.9 8.3 12.9 9.1 10.4 12.3 10.5 14.5 11.6 3.6 9.4 7.1 3.0 0.3 0.1 0.0 4.0 3.1 1.2 0.5 8.4 31.5 39.2 0.5 7.5 6.1 4.6 0.5 3.3 0.5 4.1 3.3 14.5 1.7 3.6 0.5 1.8 3.6 4.0 2.7 2.4 2.7 3.8 0.8 2.4 0.1 18.6 0.5 6.3 4.1 4.0 0.0 1.5 3.0 0.0 8.7 3.6 3.9 0.1 0.0 1.8 10.3 18.0 2.7 3.2 1.9 0.9 0.8 0.4 1.2 7.2 11.8 0.9 1.6 3.2 2.8 4.2 11.0 4.0 6.5 11.6 9.3 11.4 8.3 7.2 10.5 12.3 6.9 7.1 14.5 3.6 11.0 1.5 9.4 7.1 5.8 5.8 2.8 6.4 6.1 4.7 6.1 3.2 7.0 4.2 INSM2 "IA-6, Mlt1" ENSG00000168348 "INSM transcriptional repressor 2" Q96T92 14 35534042-35537054 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 2.3;brain: 5.2;salivary gland: 1.6;testis: 2.9" "Cell line enriched" "Detected in single" 134 "SH-SY5Y: 49.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.3" "Low region specificity" "Detected in some" "HPA044885, HPA051925" Uncertain Approved Nucleoplasm Nucleoplasm "HPA044885: AB_10794779, HPA051925: " "unprognostic (9.88e-2)" "unprognostic (8.74e-2)" "unprognostic (2.35e-1)" "unprognostic (1.08e-3)" "unprognostic (3.29e-3)" "unprognostic (1.72e-1)" "unprognostic (2.51e-1)" "unprognostic (2.26e-3)" "unprognostic (2.60e-3)" "unprognostic (7.51e-2)" "unprognostic (1.75e-2)" "unprognostic (2.36e-3)" "unprognostic (5.00e-1)" 0.3 2.3 1.0 0.5 2.8 0.2 0.3 0.5 5.2 0.2 0.2 1.0 0.0 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.8 5.0 0.2 0.2 0.3 0.2 1.9 1.2 0.2 0.2 0.2 0.1 0.2 2.7 0.2 0.2 0.7 1.6 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.2 2.9 0.2 0.2 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 49.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.8 0.5 4.6 0.8 5.0 1.9 1.2 2.7 0.2 ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506282 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 50.1;HaCaT: 55.2;HBEC3-KT: 108.5;hTCEpi: 47.3;hTERT-HME1: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 16.2" "Group enriched" "Detected in many" 34 "granulocytes: 16.2;NK-cells: 5.5;T-cells: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced 45000000 "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favourable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" 28.0 3.1 9.8 19.1 10.5 1.6 30.1 3.0 8.4 27.0 34.9 9.4 42.3 28.5 28.2 11.3 17.0 11.1 23.8 21.7 9.7 8.2 22.0 4.9 29.0 14.9 9.8 5.1 7.6 31.3 7.4 4.9 38.7 12.6 14.3 25.2 17.6 37.1 32.4 13.5 17.5 44.2 15.2 9.6 14.9 25.0 12.4 6.9 15.1 11.5 35.2 13.2 24.1 17.3 0.3 0.1 16.2 0.2 5.5 10.0 3.3 11.4 9.8 4.3 7.7 0.2 0.1 23.6 50.1 5.4 5.1 3.2 5.5 22.0 0.1 14.1 13.3 55.2 2.8 108.5 9.3 0.1 2.6 0.2 10.5 9.1 0.7 3.1 0.3 1.0 47.3 0.3 48.1 32.8 0.0 0.8 6.4 0.5 0.8 2.7 7.8 8.4 0.1 12.8 0.2 7.8 16.1 0.1 0.5 9.2 0.0 10.7 2.0 0.2 14.7 7.2 6.5 13.2 8.6 0.7 0.5 0.3 0.2 1.1 28.9 2.6 0.2 16.2 4.2 0.0 8.5 0.2 5.4 5.0 0.1 0.3 10.0 4.6 0.5 5.5 0.0 0.0 5.7 3.3 9.8 10.5 3.0 8.4 9.7 8.2 9.8 5.1 12.6 6.9 ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590065-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 7.7" "Group enriched" "Detected in many" 4 "granulocytes: 7.7;monocytes: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" 750000 "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavourable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavourable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" 23.2 22.1 17.9 18.3 21.8 3.1 25.8 16.7 23.1 22.9 13.6 23.4 11.6 8.4 26.0 11.4 14.2 14.5 25.2 40.7 16.8 12.3 51.5 9.5 20.6 7.6 24.2 11.6 35.4 18.7 65.0 11.0 29.6 22.1 16.5 11.9 83.4 17.9 15.9 13.1 21.5 10.1 29.6 33.0 12.1 17.3 11.2 17.0 7.8 33.1 10.9 11.1 17.6 17.9 0.3 0.9 7.7 2.3 0.4 1.1 0.5 9.7 11.7 7.8 24.9 28.7 19.4 29.7 19.2 15.5 6.8 6.8 10.2 33.8 0.0 37.9 21.6 12.3 3.9 18.1 9.8 1.9 3.5 2.3 15.4 14.0 11.3 1.6 1.4 14.1 8.6 15.2 12.9 16.2 2.2 4.9 18.1 3.8 0.9 1.3 5.9 5.9 0.0 15.9 1.3 17.6 75.3 1.6 4.8 22.2 6.9 8.1 5.4 4.5 49.1 42.2 13.2 8.6 16.2 1.2 2.0 1.1 17.0 0.6 20.8 7.7 1.1 1.6 1.0 2.3 0.7 0.3 0.5 0.8 0.9 0.1 0.5 0.5 0.5 0.4 1.2 0.4 1.1 0.5 17.9 21.8 16.7 17.3 16.8 12.3 24.2 11.6 22.1 17.0 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253846-47311816 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 36.6" "Cell line enhanced" "Detected in some" "EFO-21: 45.5;HEL: 40.3;RPTEC TERT1: 26.2;U-87 MG: 20.6;WM-115: 65.7" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 2.8;neutrophil: 2.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.8" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" 710000000 "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 10.0 0.6 1.0 6.2 2.5 2.7 7.0 0.4 1.6 4.6 13.6 0.9 2.4 2.2 9.7 5.7 6.4 6.4 2.8 8.5 0.7 0.6 16.0 3.7 5.2 1.2 2.3 0.1 4.6 0.6 0.7 1.6 23.5 1.6 6.4 4.8 1.8 2.5 11.5 4.9 2.4 5.0 17.0 1.8 9.5 3.6 2.6 0.6 0.2 36.6 1.9 0.9 11.0 7.8 0.1 0.0 2.8 0.1 0.0 0.0 9.5 0.0 0.4 0.1 0.0 2.3 1.0 0.0 1.2 6.0 2.6 2.4 0.0 0.0 0.1 45.5 0.3 0.0 0.0 0.0 3.4 0.8 0.0 40.3 0.1 0.0 1.9 0.0 0.0 0.9 0.0 15.2 0.3 11.3 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 1.0 0.0 26.2 0.0 0.0 0.1 1.5 0.0 8.2 0.0 0.0 12.3 0.5 0.6 0.3 2.8 0.0 0.0 0.2 20.6 0.0 65.7 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 9.5 1.0 2.5 0.4 1.6 0.7 0.6 2.3 0.1 1.6 0.6 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease mutation, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 117.5;HaCaT: 45.0;HBEC3-KT: 100.3;hTCEpi: 34.3;RT4: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" 79000 "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavourable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavourable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 6.3 3.4 9.7 10.9 9.7 1.4 13.7 4.7 7.7 14.3 32.1 15.6 10.0 35.3 9.7 8.8 24.0 13.7 47.8 4.3 9.4 7.9 4.8 1.5 7.4 3.7 10.1 9.1 4.7 6.7 3.1 5.7 50.0 17.2 19.7 10.4 9.8 52.3 13.2 2.4 47.0 58.5 7.4 10.7 17.0 41.0 3.9 9.8 1.8 3.2 22.1 15.9 17.2 20.5 2.4 8.2 1.3 0.7 0.0 2.2 0.8 21.8 19.3 0.0 0.2 0.0 0.1 26.6 0.1 0.0 0.0 0.1 2.0 117.5 0.0 4.2 0.0 45.0 0.1 100.3 0.0 0.1 0.0 0.1 4.9 2.1 0.1 0.0 0.2 0.1 34.3 0.0 21.4 0.7 0.0 2.0 0.0 12.2 0.2 0.2 0.1 16.8 0.3 0.5 0.2 26.8 33.0 0.0 0.2 0.6 2.0 0.3 8.4 0.2 2.2 0.6 1.0 0.0 0.2 0.7 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.0 0.7 0.7 2.2 1.4 0.3 1.0 0.1 2.4 0.9 0.6 1.3 0.0 0.0 8.2 1.4 0.8 9.7 9.7 4.7 7.7 9.4 7.9 10.1 9.1 17.2 9.8 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 33.1;kidney: 51.5;pancreas: 42.1" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 30.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020192, HPA024127" Uncertain Approved Nucleoplasm Nucleoplasm "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.4 0.0 0.8 0.8 1.2 0.0 9.1 0.8 0.6 3.3 5.8 0.4 3.3 11.8 4.7 18.0 0.5 3.8 33.1 0.4 0.4 0.2 51.5 9.8 1.0 0.4 0.4 0.5 1.1 42.1 0.0 0.6 1.3 0.4 2.4 1.7 0.8 1.8 4.2 0.4 0.4 7.3 0.4 0.4 0.4 5.5 1.5 0.4 1.0 11.6 0.4 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 3.6 0.0 0.0 0.1 0.1 0.2 0.0 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 0.1 0.4 0.0 0.0 0.0 30.9 0.1 4.5 0.1 0.0 0.6 0.0 3.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.8 0.6 0.4 0.2 0.4 0.5 0.4 0.4 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689443-23955066 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 70.8" "Cell line enriched" "Detected in some" 5 "HBEC3-KT: 150.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" 810000 "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavourable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 8.2 0.9 2.9 8.2 1.9 0.0 16.7 0.6 2.3 18.2 13.3 2.4 5.4 11.2 19.1 9.5 12.4 7.8 8.1 2.7 1.8 1.5 3.1 1.3 26.2 7.0 2.4 0.9 5.8 3.1 10.3 2.3 70.8 1.6 8.7 5.2 5.7 14.9 9.1 2.2 20.7 27.8 10.2 1.3 0.8 19.7 3.8 0.5 3.3 1.8 9.7 8.0 11.5 15.2 0.0 0.0 0.8 0.0 0.0 1.3 0.2 16.9 2.1 0.0 0.0 0.9 0.1 0.0 0.3 0.2 0.1 0.2 0.7 19.6 0.0 2.2 0.2 31.0 0.0 150.6 0.1 0.0 1.2 0.0 0.6 0.3 0.1 0.0 0.0 0.1 16.9 0.1 17.8 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 2.0 0.3 0.0 0.0 6.6 1.9 0.0 0.3 0.7 0.2 0.0 0.5 0.2 1.6 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 2.9 1.9 0.6 2.3 1.8 1.5 2.4 0.9 1.6 0.5 LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037515 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 104.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" 390000 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" 9.8 4.7 5.6 12.0 7.3 13.2 7.7 23.3 12.9 6.3 7.6 6.9 7.8 4.2 8.2 4.4 10.2 6.6 4.3 10.1 5.2 5.6 7.6 4.3 6.9 15.9 7.7 8.8 8.2 5.9 13.8 9.7 104.4 9.1 7.9 6.8 3.9 7.8 7.7 13.2 14.0 9.0 6.6 7.5 10.0 8.5 3.3 7.7 23.6 7.2 2.9 15.8 8.9 7.7 4.1 3.5 5.0 12.8 11.2 7.9 4.3 5.3 6.2 2.8 3.0 17.1 8.2 3.3 5.5 7.3 6.5 9.9 5.2 8.7 26.5 10.4 7.4 7.1 3.6 10.4 6.8 9.4 2.0 6.6 4.5 3.6 4.4 7.6 9.2 6.3 6.5 9.4 6.9 6.8 2.8 17.6 7.4 4.8 9.0 5.3 0.6 3.3 6.6 10.6 4.0 23.2 11.1 5.5 1.4 6.7 5.9 3.3 18.1 10.1 13.5 9.5 5.3 7.5 8.3 3.8 8.8 24.2 8.4 7.3 4.3 5.0 3.3 4.4 7.9 5.5 6.8 3.1 5.9 6.1 3.5 4.1 5.9 6.4 4.1 11.2 12.8 3.3 5.1 4.3 5.6 7.3 23.3 12.9 5.2 5.6 7.7 8.8 9.1 7.7 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell line enhanced" "Detected in many" "SCLC-21H: 38.6" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332" Enhanced "Plasma membrane" "Plasma membrane" "HPA058921: , HPA070332: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favourable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 3.0 12.8 33.3 2.1 29.6 1.4 2.7 24.9 73.5 3.1 1.9 4.6 0.1 1.6 4.9 3.1 2.1 6.6 3.0 2.9 38.1 22.3 5.1 2.7 2.6 1.0 28.0 18.9 4.4 26.4 14.7 24.8 1.6 23.5 4.9 1.5 4.5 4.8 5.0 1.7 1.7 2.0 4.4 44.4 1.7 3.8 10.8 4.8 0.0 3.9 0.5 0.9 2.0 0.4 0.4 0.4 2.1 0.9 2.6 0.2 0.0 0.0 3.5 4.7 13.1 1.8 0.9 0.1 2.5 2.2 5.0 3.6 3.0 0.5 0.2 1.2 2.9 2.8 5.0 2.3 2.2 1.9 6.5 0.0 4.4 2.0 1.6 0.2 2.2 1.2 0.5 3.2 0.6 1.1 5.4 0.8 1.4 1.8 0.1 0.3 12.5 5.2 0.3 7.7 0.1 2.3 0.0 38.6 14.4 4.1 3.4 4.7 5.5 0.2 1.0 6.4 9.8 9.5 4.5 0.5 0.6 0.2 4.0 0.1 1.9 2.1 0.9 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.4 0.1 0.2 1.8 2.6 0.0 0.4 0.1 0.0 33.3 29.6 24.9 41.7 38.1 22.3 28.0 18.9 23.5 4.8 MIIP "FLJ12438, IIp45" ENSG00000116691 "Migration and invasion inhibitory protein" Q5JXC2 1 12019466-12032045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "HDLM-2: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044948 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA044948: AB_10795887" "unprognostic (1.36e-2)" "unprognostic (1.95e-2)" "unprognostic (5.02e-3)" "unprognostic (3.59e-2)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (4.65e-3)" "unprognostic (7.16e-2)" "unprognostic (2.97e-1)" "unprognostic (4.03e-2)" "unprognostic (3.73e-3)" "unprognostic (6.56e-2)" "prognostic unfavourable (8.26e-7)" "unprognostic (8.02e-3)" "unprognostic (5.09e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" 13.2 9.4 12.2 17.0 17.3 53.4 10.8 13.7 15.3 11.1 11.4 11.9 11.6 11.0 16.5 8.8 11.1 13.0 8.9 13.3 12.9 10.1 9.2 11.7 13.3 18.3 15.9 10.6 20.4 13.5 5.8 7.1 14.6 17.0 11.3 4.5 8.5 18.1 14.2 26.3 14.8 12.7 12.3 11.0 20.4 10.0 18.2 15.2 10.5 22.5 9.7 12.5 12.3 11.9 14.8 45.0 18.3 27.1 10.6 19.0 12.5 4.9 3.3 2.6 5.1 1.4 1.6 9.2 2.7 1.4 5.3 4.0 6.5 7.9 6.3 6.4 1.4 5.1 1.9 3.0 0.6 88.7 7.4 3.9 5.3 6.8 3.0 5.9 12.1 2.1 3.9 4.6 2.0 2.9 11.7 5.8 1.6 5.0 5.9 8.9 4.7 5.0 8.4 3.3 9.6 2.2 1.5 4.9 5.2 3.9 5.0 9.6 3.3 10.4 3.1 4.8 5.2 9.7 4.1 4.9 6.2 8.4 3.1 10.4 4.9 4.9 23.2 7.1 9.0 25.9 8.4 14.8 9.3 7.8 14.2 13.0 5.8 4.5 18.3 10.6 27.1 45.0 19.0 12.5 12.2 17.3 13.7 15.3 12.9 10.1 15.9 10.6 17.0 15.2 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716496 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.9;bone marrow: 33.0;lymphoid tissue: 49.2" "Cell line enhanced" "Detected in many" "MCF7: 101.9" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 30 "plasmacytoid DC: 35.9" "Lineage enriched" "Detected in many" 30 "dendritic cells: 35.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017114: , HPA030530: , HPA055416: " "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavourable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.7 0.7 0.2 48.3 0.2 33.0 1.0 0.2 0.2 1.0 4.4 0.2 0.1 2.7 1.1 1.1 8.4 0.3 1.7 0.9 0.2 0.2 1.0 1.2 1.8 22.3 0.3 0.1 0.8 9.4 0.0 0.4 4.0 0.2 0.7 2.7 0.3 2.9 0.1 0.3 1.8 6.4 0.6 0.3 43.9 2.9 12.6 0.1 49.2 0.6 6.4 33.8 1.9 2.1 1.1 35.9 0.0 0.0 0.0 0.4 0.3 25.8 16.5 14.6 15.1 0.1 0.5 19.0 11.7 4.0 37.1 27.4 80.9 16.3 52.3 6.8 5.1 15.8 26.4 8.1 13.9 9.8 16.9 24.5 16.5 21.8 0.0 22.3 17.0 0.3 0.7 14.1 3.2 9.9 24.4 65.1 3.2 101.9 45.3 31.4 16.8 14.5 31.6 30.1 30.0 6.8 5.3 13.5 19.6 34.8 35.0 3.5 23.1 24.5 4.6 2.3 37.4 16.4 20.1 22.6 46.5 82.3 4.8 19.1 14.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 35.9 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.1 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366670-34376853 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 56.1" "Cell line enhanced" "Detected in many" "Hep G2: 17.4;SK-BR-3: 29.1;T-47d: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Approved Approved Mitochondria Mitochondria "HPA060533: , HPA067487: " "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavourable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favourable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 6.3 5.6 16.7 4.7 20.5 2.1 3.5 6.9 16.0 2.0 19.9 9.8 1.3 20.9 2.2 2.8 4.8 3.6 11.6 2.9 11.1 8.7 11.7 31.8 3.1 1.7 11.2 12.6 1.6 16.6 2.0 4.0 15.4 10.7 3.2 13.1 0.5 4.7 4.9 56.1 3.6 26.7 4.8 7.0 1.7 9.9 1.7 6.9 0.0 2.2 6.4 2.1 3.5 1.9 1.1 0.8 1.9 0.8 1.9 3.3 0.6 4.0 2.9 4.8 2.9 2.0 0.7 10.3 0.8 0.6 0.4 0.7 7.1 4.3 2.2 8.3 0.7 8.4 3.4 7.8 0.6 0.7 1.9 0.4 12.9 17.4 0.3 0.4 1.4 1.0 3.7 1.3 1.6 1.9 0.5 2.4 1.0 6.7 1.2 0.7 2.9 2.3 2.1 2.5 0.7 2.6 1.5 0.7 6.7 5.8 29.1 0.5 27.0 0.7 1.7 1.1 6.0 0.9 1.8 1.5 3.2 0.9 0.9 1.6 0.9 1.9 0.6 1.2 3.3 0.6 2.6 0.8 2.0 1.9 0.3 1.1 1.3 1.6 1.6 1.9 0.8 0.8 2.6 0.6 16.7 20.5 6.9 16.0 11.1 8.7 11.2 12.6 10.7 6.9 NKX3-1 "BAPX2, NKX3.1, NKX3A" ENSG00000167034 "NK3 homeobox 1" Q99801 8 23678693-23682927 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "prostate: 95.3" "Cell line enhanced" "Detected in many" "SiHa: 17.5;U-138 MG: 17.8;U-251 MG: 15.2" "Cancer enriched" "Detected in many" 65 "prostate cancer: 392.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 7 "eosinophil: 23.5;neutrophil: 23.4" "Lineage enriched" "Detected in many" 19 "granulocytes: 23.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025693, HPA078571" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA025693: AB_1854522, HPA078571: " "unprognostic (1.47e-2)" "unprognostic (4.03e-2)" "unprognostic (2.67e-1)" "unprognostic (5.87e-2)" "unprognostic (2.56e-6)" "unprognostic (6.90e-3)" "unprognostic (1.13e-1)" "unprognostic (4.11e-3)" "unprognostic (9.42e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.37e-2)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" 0.6 1.3 0.3 0.6 0.9 0.6 1.5 0.1 0.8 1.1 0.6 0.2 0.5 0.5 0.7 0.5 1.2 0.7 0.8 2.4 0.8 0.3 0.4 1.6 0.8 0.7 0.6 0.2 1.6 0.6 0.5 0.4 0.3 1.2 95.3 0.2 0.5 17.9 0.7 2.0 0.2 0.4 0.7 0.6 0.3 0.5 12.3 0.7 0.0 0.6 3.2 20.5 0.7 2.5 1.0 0.0 23.5 0.0 0.2 1.2 0.1 3.2 2.4 0.0 5.9 2.2 0.5 4.9 4.4 2.8 9.5 11.2 1.4 3.7 0.0 0.6 3.3 0.8 2.3 5.1 7.5 0.0 1.2 2.2 1.8 3.5 4.2 0.0 0.8 0.8 1.3 9.6 0.5 0.5 0.1 0.0 3.7 1.0 7.6 0.6 1.4 1.7 0.0 3.8 0.3 0.5 3.8 1.1 0.3 17.5 3.3 0.3 2.3 0.3 0.6 17.8 6.3 1.3 15.2 0.0 0.0 0.0 8.7 1.7 2.1 3.4 0.0 23.5 0.5 0.0 0.1 1.0 0.2 0.5 0.0 0.9 0.7 1.2 23.4 0.2 0.0 0.0 0.0 0.1 0.3 0.9 0.1 0.8 0.8 0.3 0.6 0.2 1.2 0.7 PAX4 MODY9 ENSG00000106331 "Paired box 4" O43316 7 127610292-127618114 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 3.9;testis: 3.6" "Cell line enriched" "Detected in single" 62 "SCLC-21H: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (1.52e-1)" "unprognostic (9.71e-2)" "unprognostic (4.86e-3)" "unprognostic (1.21e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 3.4 0.1 0.1 3.8 0.1 0.8 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 3.9 0.1 0.1 0.1 0.1 0.0 2.1 0.1 0.1 0.1 0.0 3.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 50.7" "Cell line enhanced" "Detected in some" "AN3-CA: 9.9;HMC-1: 5.3;U-266/70: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.2;plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.7;T-cells: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA005572 Uncertain "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favourable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.5 1.2 2.5 0.6 3.4 0.9 0.7 0.6 1.8 1.2 0.9 1.8 2.5 2.5 0.8 2.2 0.7 4.2 1.0 0.4 2.5 2.1 1.7 2.0 0.8 0.6 1.0 2.0 0.8 3.8 1.4 4.2 0.5 2.3 1.2 0.4 2.4 1.3 2.4 0.5 0.8 1.1 0.6 1.2 0.7 1.2 50.7 1.8 1.2 2.0 0.0 0.4 0.7 0.6 0.0 1.7 0.0 0.3 0.0 1.2 0.1 0.8 0.5 1.7 9.9 0.2 0.3 2.6 0.7 0.2 0.1 0.3 0.9 1.4 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.6 0.2 0.4 1.4 1.3 0.7 0.0 5.3 0.8 0.0 0.0 0.1 0.2 1.6 2.5 0.0 0.0 0.2 0.4 0.1 0.5 1.7 0.1 0.2 0.6 0.0 0.0 2.0 0.2 0.4 0.1 3.6 0.5 0.0 0.8 0.1 0.2 0.0 10.9 1.9 0.3 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.7 0.0 0.1 2.5 3.4 0.6 1.8 2.5 2.1 1.0 2.0 2.3 1.8 PHEX "HPDR, HPDR1, HYP, HYP1, PEX, XLH" ENSG00000102174 "Phosphate regulating endopeptidase homolog X-linked" P78562 X 22032441-22251310 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Biomineralization "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 8.3;lung: 6.7" "Cell line enhanced" "Detected in some" "HBEC3-KT: 5.6;HUVEC TERT2: 4.3;PC-3: 4.7;TIME: 4.8;U-87 MG: 10.3;WM-115: 4.3" "Cancer enhanced" "Detected in some" "thyroid cancer: 5.9" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 37 "plasmacytoid DC: 8.3" "Lineage enriched" "Detected in single" 37 "dendritic cells: 8.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "unprognostic (2.01e-2)" "unprognostic (2.69e-1)" "unprognostic (2.43e-1)" "unprognostic (1.05e-3)" "unprognostic (1.22e-1)" "unprognostic (3.04e-2)" "unprognostic (2.25e-3)" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-2)" "unprognostic (7.53e-2)" "unprognostic (7.45e-2)" "unprognostic (9.84e-8)" "unprognostic (1.18e-1)" "unprognostic (1.58e-1)" "prognostic favourable (2.51e-4)" "unprognostic (7.68e-2)" 0.3 0.0 1.8 1.9 1.1 0.0 1.7 0.9 1.1 0.8 0.9 0.8 0.3 1.2 5.0 0.3 0.4 0.1 2.0 0.3 1.5 1.8 0.3 0.3 6.7 3.4 2.0 0.3 3.9 0.3 0.0 0.3 0.3 5.0 1.3 0.0 0.3 2.8 0.9 0.3 0.1 1.4 3.9 3.8 3.4 0.0 0.3 0.3 1.3 4.8 0.3 4.3 0.5 0.6 0.1 8.3 0.0 0.0 0.0 0.2 0.0 0.3 0.8 0.2 0.1 0.1 0.4 0.0 0.0 0.1 0.1 0.3 1.3 0.1 0.1 1.3 0.1 0.1 0.0 5.6 0.3 0.0 0.1 0.1 0.5 0.0 0.1 0.1 0.2 2.2 1.1 1.1 3.3 4.3 0.0 0.4 0.5 0.0 0.0 0.2 0.0 4.7 0.0 1.0 0.0 0.6 0.2 0.1 0.2 0.4 2.4 0.8 2.8 0.0 4.8 1.0 0.1 0.6 0.8 0.0 0.0 0.0 10.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 0.0 0.0 1.8 1.1 0.9 1.1 1.5 1.8 2.0 0.3 5.0 0.3 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76033932 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "salivary gland: 142.4" "Cell line enhanced" "Detected in many" "hTERT-HME1: 43.3;RPTEC TERT1: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.4;MAIT T-cell: 3.9;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.5;non-classical monocyte: 2.5;T-reg: 4.1" "Group enriched" "Detected in many" 7 "monocytes: 2.5;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: " "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 13.2 15.9 9.4 8.4 12.1 9.0 13.5 6.4 15.7 11.5 4.5 11.1 4.8 3.4 7.1 3.1 33.3 5.1 20.0 9.6 8.2 7.9 13.8 33.2 14.2 3.0 8.4 5.6 10.8 8.8 2.6 6.0 7.1 10.0 4.8 5.5 24.9 142.4 6.5 3.3 6.3 7.0 7.6 9.7 14.6 10.8 2.3 10.1 2.5 18.0 13.2 19.9 17.0 17.8 0.3 0.1 0.4 2.5 0.3 4.1 0.6 13.5 16.3 12.8 7.0 6.0 12.4 0.9 11.5 31.1 5.2 7.3 9.0 16.6 0.0 3.5 4.8 7.0 0.3 19.3 11.3 2.0 0.2 0.3 0.8 15.2 8.7 0.3 3.5 3.8 14.2 21.8 43.3 12.5 1.1 0.4 26.8 1.7 0.0 1.7 4.6 25.2 0.0 3.3 0.4 54.9 30.8 0.9 2.4 2.0 0.1 37.4 8.2 0.1 11.6 17.9 1.7 20.8 11.3 0.2 0.0 0.0 30.2 0.2 22.3 0.3 0.1 0.2 2.4 0.2 3.9 0.3 2.5 2.5 0.0 0.2 0.5 0.6 0.4 0.3 2.5 0.1 4.1 0.6 9.4 12.1 6.4 7.7 8.2 7.9 8.4 5.6 10.0 10.1 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 56.7" "Cell line enhanced" "Detected in many" "CACO-2: 21.6;Hep G2: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" 5400 "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: , HPA057910: " "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 5.6 7.0 13.8 4.4 27.7 3.4 5.9 7.5 31.1 6.5 9.9 2.1 20.6 5.5 8.0 10.3 4.5 7.4 6.6 8.6 15.7 9.1 10.0 3.1 4.0 1.6 9.3 14.5 3.2 10.8 56.7 4.6 14.2 5.5 10.4 3.6 1.3 19.7 22.2 9.8 2.3 4.5 12.3 4.0 2.9 5.5 2.6 8.0 4.1 3.1 1.9 1.1 8.6 6.3 0.5 0.8 2.8 3.3 2.4 5.2 0.4 0.0 0.6 2.3 0.1 4.3 8.1 3.1 9.7 6.4 2.5 1.5 21.6 2.4 1.0 4.1 1.8 0.0 1.7 0.0 1.9 0.0 2.1 0.4 1.6 32.5 1.1 0.5 0.3 0.5 0.4 3.4 0.0 5.1 3.3 12.6 0.0 2.9 0.4 1.5 7.3 3.5 6.9 0.0 5.7 1.9 8.0 8.3 3.6 0.0 2.0 0.4 9.6 3.1 0.9 8.3 3.7 0.6 6.0 9.5 11.0 16.3 4.2 5.9 14.3 0.8 3.3 2.8 3.6 0.7 5.2 0.2 1.0 1.3 0.4 0.5 0.5 1.1 2.1 2.4 0.4 0.8 0.2 0.4 13.8 27.7 7.5 30.8 15.7 9.1 9.3 14.5 5.5 8.0 POU1F1 "GHF-1, PIT1, POU1F1a" ENSG00000064835 "POU class 1 homeobox 1" P28069 3 87259404-87276587 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "pituitary gland: 138.8" "Cell line enhanced" "Detected in some" "A549: 1.8;SiHa: 1.1;U-87 MG: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041646, HPA050624" Enhanced "HPA041646: AB_10794672, HPA050624: AB_2681192" "unprognostic (1.88e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.60e-1)" "unprognostic (2.93e-1)" "unprognostic (1.87e-2)" "unprognostic (7.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.50e-1)" "unprognostic (4.69e-3)" "unprognostic (1.55e-1)" "unprognostic (1.52e-2)" "unprognostic (1.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.05e-4)" 0.3 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 138.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.8 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952118-68237030 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AF22: 12.7;HUVEC TERT2: 17.3;NTERA-2: 11.0;RH-30: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: " "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavourable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 18.8 3.0 14.1 3.3 17.9 1.0 8.5 11.4 16.4 10.8 4.4 13.1 3.0 4.3 6.2 4.5 4.4 12.4 7.6 7.6 15.5 8.1 4.1 3.2 9.1 2.4 12.4 10.0 5.2 3.1 3.7 4.4 17.5 17.2 6.3 4.4 2.6 3.0 5.7 4.9 4.4 4.0 6.1 12.7 3.5 4.1 2.7 16.2 0.0 12.1 3.9 2.9 5.9 15.8 1.1 0.3 0.8 0.1 0.2 0.4 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 2.6 0.0 11.0 0.0 0.0 5.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.2 0.0 1.1 0.2 0.3 0.5 0.2 0.1 0.3 0.0 0.0 14.1 17.9 11.4 13.6 15.5 8.1 12.4 10.0 17.2 16.2 PRRC2A "BAT2, D6S51E, G2" ENSG00000204469 "Proline rich coiled-coil 2A" P48634 6 31620720-31637771 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HBEC3-KT: 25.9;HEK 293: 47.2;U-266/70: 24.3;U-266/84: 25.8;U-698: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026383, HPA046791, HPA066501" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "CAB026383: , HPA046791: , HPA066501: " "unprognostic (2.07e-1)" "unprognostic (6.84e-2)" "unprognostic (3.82e-1)" "unprognostic (2.25e-3)" "unprognostic (5.04e-2)" "unprognostic (4.63e-1)" "unprognostic (2.42e-3)" "unprognostic (2.09e-1)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-3)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (5.40e-2)" "unprognostic (3.10e-1)" 10.9 18.4 20.7 28.9 22.1 5.0 12.2 25.2 29.1 15.0 24.6 18.4 11.9 4.8 19.7 51.5 47.2 32.3 13.8 24.2 18.4 13.2 16.0 10.2 41.7 14.9 14.3 20.4 29.3 12.2 4.8 18.5 8.6 15.9 30.9 7.1 15.0 12.3 15.9 35.1 28.8 23.0 12.8 11.5 43.5 34.6 46.3 16.7 27.1 16.8 10.4 14.4 16.0 13.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 11.7 11.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 7.4 13.1 0.0 0.0 25.9 0.0 0.0 47.2 0.1 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.0 0.0 24.3 25.8 24.6 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 22.1 25.2 29.1 18.4 13.2 14.3 20.4 15.9 16.7 RAB4A "HRES-1/RAB4, RAB4" ENSG00000168118 "RAB4A, member RAS oncogene family" P20338 1 229271062-229305894 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 21.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 21.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.21e-2)" "unprognostic (7.58e-2)" "unprognostic (1.81e-2)" "unprognostic (2.09e-1)" "unprognostic (2.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-1)" "unprognostic (8.53e-2)" "unprognostic (6.41e-2)" "unprognostic (3.85e-2)" "unprognostic (2.99e-2)" "unprognostic (2.47e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (4.26e-2)" "unprognostic (1.72e-2)" 12.0 13.6 25.8 11.0 23.4 6.4 19.8 26.6 27.0 20.6 17.2 19.7 15.7 16.9 13.1 14.4 18.2 15.9 17.9 36.9 23.2 26.6 15.9 29.6 11.0 10.8 32.0 15.6 16.8 27.8 12.4 11.2 11.4 24.2 35.5 19.6 14.7 38.2 22.5 30.2 16.8 13.1 18.6 26.4 7.7 24.6 13.1 18.9 12.2 20.2 16.8 12.2 17.9 15.7 2.0 4.6 21.0 4.2 1.4 2.2 2.3 5.1 7.0 11.8 8.2 17.0 19.0 9.9 7.8 9.4 4.8 4.6 13.0 8.7 0.0 13.2 10.5 5.7 7.8 11.1 6.8 6.5 15.6 7.0 6.3 20.2 11.0 14.0 5.7 14.5 16.0 3.3 4.7 10.8 7.2 0.0 8.3 6.6 7.0 9.4 10.6 9.7 2.3 1.9 3.6 25.4 12.4 10.2 13.3 6.5 9.9 13.5 9.4 25.1 7.5 0.0 3.8 7.6 10.7 6.2 5.7 0.0 3.4 12.0 11.2 12.5 3.6 21.0 1.6 4.2 1.5 1.9 2.1 2.0 4.6 2.0 1.3 1.7 0.9 1.4 2.7 2.5 2.2 2.3 25.8 23.4 26.6 27.0 23.2 26.6 32.0 15.6 24.2 18.9 RAB4B "FLJ78649, MGC52123" ENSG00000167578 "RAB4B, member RAS oncogene family" P61018 19 40778216-40796938 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "unprognostic (9.11e-3)" "unprognostic (2.67e-3)" "unprognostic (4.23e-3)" "unprognostic (4.02e-2)" "unprognostic (1.62e-1)" "unprognostic (4.73e-3)" "unprognostic (5.74e-2)" "unprognostic (7.93e-2)" "unprognostic (5.32e-1)" "unprognostic (2.46e-2)" "prognostic favourable (2.08e-4)" "unprognostic (7.73e-2)" "prognostic unfavourable (1.28e-4)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "prognostic favourable (1.99e-5)" 13.6 19.1 22.0 16.2 23.7 13.1 7.2 17.1 39.7 10.4 15.3 31.2 8.4 14.6 7.6 4.5 9.4 8.7 11.4 8.4 24.5 22.8 8.2 7.9 13.0 22.8 26.5 17.8 4.6 12.4 4.5 16.8 19.0 24.0 10.3 7.4 10.8 11.2 12.5 5.2 9.7 15.9 7.1 36.9 19.8 15.8 9.6 18.8 11.6 9.5 5.5 14.1 8.7 7.3 31.1 49.5 36.9 26.8 11.7 21.4 20.6 6.1 20.1 4.7 8.2 10.7 7.6 7.0 8.2 7.7 3.6 9.6 11.0 6.9 10.2 14.1 6.6 5.7 2.1 7.2 1.7 23.4 9.1 8.1 3.9 6.7 16.8 7.2 29.5 13.8 7.4 7.6 1.9 13.5 4.2 18.2 7.5 9.9 10.6 11.6 3.8 9.5 9.4 4.0 9.9 10.2 12.1 4.3 7.8 18.6 5.6 8.4 5.9 15.5 10.1 9.1 6.6 7.7 3.3 10.7 6.4 10.0 17.5 9.2 9.5 23.4 21.8 36.5 21.4 26.8 11.7 23.8 13.9 18.4 26.7 31.1 13.0 15.7 36.9 11.7 19.2 49.5 18.9 20.6 22.0 23.7 17.1 39.7 24.5 22.8 26.5 17.8 24.0 18.8 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 63.6" "Cell line enhanced" "Detected in some" "A-431: 2.3;BJ: 4.8;HMC-1: 6.3;RT4: 1.8;SK-BR-3: 4.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enriched" "Detected in single" 12 "basal ganglia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005131, CAB025903" Approved "Secreted to blood" 692000 "CAB025903: , HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 0.0 1.2 0.0 0.5 0.0 0.0 3.1 0.2 0.0 0.8 0.1 4.4 13.5 0.1 0.3 0.0 0.6 0.0 0.0 63.6 0.4 0.3 0.0 0.0 0.0 11.6 0.0 0.0 0.4 14.4 0.0 0.3 0.1 0.4 0.3 0.5 0.0 0.0 0.1 1.0 0.0 0.0 0.0 2.0 0.0 0.0 1.1 0.0 0.2 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 4.8 0.9 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 6.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 4.5 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RLN3 "H3, RXN3, ZINS4" ENSG00000171136 "Relaxin 3" Q8WXF3 19 14028148-14031042 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 2.7;parathyroid gland: 5.6;testis: 5.0" "Cell line enhanced" "Detected in some" "BEWO: 1.0;K-562: 4.0;SCLC-21H: 1.5;THP-1: 2.2;U-266/70: 1.0;U-698: 1.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 11 "midbrain: 14.0;pons and medulla: 28.5" "Region enriched" "Detected in some" 9 "pons and medulla: 34.0" "Secreted to blood" 60034685 "unprognostic (1.96e-2)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" 0.3 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.9 1.3 0.1 0.0 5.6 0.2 0.0 0.7 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.0 1.0 0.1 5.0 0.0 0.4 0.2 0.0 2.7 1.8 0.0 1.3 0.0 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.1 0.0 0.9 0.9 1.8 2.7 2.0 1.2 0.0 0.0 0.3 0.0 0.2 0.5 RPS15 "MGC111130, RIG, S15" ENSG00000115268 "Ribosomal protein S15" P62841 19 1438358-1440494 "Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054510, HPA057793" Enhanced Approved "Endoplasmic reticulum,Cytosol" 170000 "Endoplasmic reticulum, Cytosol" "HPA054510: AB_2682510, HPA057793: AB_2683528" "unprognostic (4.47e-3)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.08e-3)" "unprognostic (5.98e-2)" "unprognostic (2.05e-1)" "unprognostic (4.33e-3)" "unprognostic (4.42e-2)" "unprognostic (2.58e-1)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (5.00e-2)" "unprognostic (1.44e-3)" "unprognostic (5.21e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.61e-2)" 61.7 61.2 63.0 67.5 51.4 123.6 74.2 46.0 87.5 56.2 66.4 46.1 41.2 69.0 73.6 52.3 80.9 61.2 73.7 72.1 50.4 40.5 64.8 103.7 43.0 95.3 52.1 52.6 144.8 136.0 21.6 59.3 60.9 45.2 66.9 37.1 61.2 123.7 53.2 154.9 102.4 67.6 51.8 51.0 76.2 63.5 60.8 24.9 70.7 74.2 127.6 82.9 47.6 70.9 237.3 149.5 48.6 106.7 103.8 218.1 269.2 103.1 110.2 48.5 65.9 45.5 66.3 83.6 54.1 43.2 64.9 50.9 176.9 36.5 128.1 48.7 34.7 65.8 47.2 67.0 25.5 106.5 246.9 41.9 101.0 167.0 48.2 106.6 80.0 81.4 81.0 43.9 43.1 57.1 85.0 184.5 40.5 181.6 88.0 143.3 109.7 141.8 91.7 57.9 167.3 58.9 113.7 78.1 92.7 45.6 78.7 155.1 60.2 143.7 57.6 55.0 63.0 109.6 119.3 160.3 158.6 124.5 54.6 97.4 62.8 48.6 106.7 44.5 116.2 89.5 160.8 237.3 179.3 146.1 149.5 222.5 218.1 177.4 21.6 103.8 68.2 124.2 162.9 269.2 63.0 51.4 46.0 87.5 50.4 40.5 52.1 52.6 45.2 24.9 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405948-111451623 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 31.8;hTEC/SVTERT24-B: 36.4;U-87 MG: 55.3;WM-115: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavourable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 17.6 9.0 7.9 13.7 7.9 34.4 19.8 3.8 9.3 8.9 7.5 7.2 3.1 5.3 8.0 7.1 5.6 7.5 12.7 15.3 5.8 5.5 9.2 12.5 17.6 27.8 6.6 4.0 8.2 11.0 4.7 7.6 16.1 5.2 8.4 9.3 8.7 5.0 4.2 10.2 3.6 10.3 9.1 7.8 31.7 5.5 13.3 6.8 9.5 10.2 3.2 11.8 10.0 5.8 1.8 6.1 3.8 10.3 2.3 1.7 1.9 2.2 1.3 1.8 1.8 6.3 9.5 1.2 7.4 20.3 5.7 6.1 2.1 1.3 3.9 5.3 11.2 0.4 1.4 4.2 9.2 3.2 0.6 13.2 0.6 1.5 6.2 5.8 31.8 5.6 0.9 36.4 3.3 30.4 9.5 1.5 20.6 0.8 2.3 11.6 2.8 5.4 2.3 4.1 2.5 2.7 0.9 1.2 1.2 1.3 0.1 10.6 0.9 8.3 23.5 5.2 2.9 4.5 12.0 3.6 3.7 4.4 55.3 4.2 42.2 1.1 4.3 1.5 1.6 10.3 1.4 1.8 1.4 1.7 5.9 0.7 1.0 1.3 3.8 2.3 7.6 6.1 0.5 1.9 7.9 7.9 3.8 9.3 5.8 5.5 6.6 4.0 5.2 6.8 SLC29A3 "ENT3, FLJ11160" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319258-71381423 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 19.5;Hep G2: 21.7;RT4: 17.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046085, HPA054976, HPA057905" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA046085: , HPA054976: , HPA057905: " "unprognostic (1.73e-1)" "unprognostic (2.38e-3)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.73e-2)" "prognostic unfavourable (6.07e-6)" "unprognostic (1.28e-1)" "unprognostic (4.71e-1)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (3.80e-2)" "prognostic unfavourable (5.53e-5)" "unprognostic (3.37e-1)" "unprognostic (1.36e-1)" "prognostic favourable (1.16e-4)" "unprognostic (3.43e-3)" 11.3 4.0 6.4 6.6 8.3 1.9 6.8 3.2 12.6 8.3 6.1 11.3 2.4 4.1 12.1 4.6 3.5 9.4 7.4 3.6 8.0 5.5 3.9 12.5 11.1 10.5 9.8 6.5 15.8 7.4 7.1 2.8 24.6 6.7 8.3 6.0 4.6 7.5 5.4 2.1 3.7 4.9 8.9 8.0 9.4 8.9 4.9 7.7 9.3 6.7 1.3 6.2 18.4 10.0 3.6 19.3 2.8 12.9 5.7 4.0 5.6 1.2 7.3 1.0 4.6 4.2 3.3 19.5 1.3 1.4 0.4 0.2 8.0 5.2 4.2 3.9 2.7 11.6 3.3 1.8 0.0 3.3 3.3 1.2 0.6 21.7 2.0 1.0 2.7 3.2 8.0 0.1 0.3 1.9 3.9 4.1 0.5 11.3 2.7 2.1 2.5 2.6 3.3 0.4 3.4 1.6 17.3 5.5 5.8 3.9 12.7 1.0 1.9 2.3 3.0 0.1 2.4 1.3 0.0 1.1 1.8 2.3 5.1 14.3 0.8 2.8 12.9 1.4 4.0 10.1 3.4 3.6 3.2 3.6 19.3 1.5 2.6 3.6 1.0 5.7 6.3 13.6 3.4 5.6 6.4 8.3 3.2 12.6 8.0 5.5 9.8 6.5 6.7 7.7 TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853978 "Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 45.3" "Cell line enhanced" "Detected in many" "BEWO: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Supported "Endoplasmic reticulum,Centriolar satellite" 110000 "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: " "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favourable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favourable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavourable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" 10.7 7.9 3.8 20.4 5.2 6.1 8.7 3.1 4.9 6.5 12.6 4.5 1.9 9.1 8.2 3.9 10.5 6.4 9.6 6.5 3.5 3.3 6.5 6.4 17.6 26.9 6.4 3.6 5.0 4.4 3.0 3.6 8.7 6.0 9.0 5.4 6.6 9.4 4.4 7.5 15.3 19.5 5.7 5.2 24.2 12.6 5.8 4.9 20.8 13.1 8.9 20.3 6.6 7.6 22.7 8.8 45.3 10.9 14.4 25.3 21.0 2.8 1.8 0.0 1.7 0.9 1.2 16.6 1.5 3.4 6.9 9.4 0.1 3.0 5.9 3.9 1.1 5.5 1.1 2.4 0.4 10.1 1.5 6.6 1.3 2.3 4.3 0.0 2.4 1.3 2.1 1.9 1.2 1.7 0.4 5.6 0.8 1.7 1.1 13.1 0.0 1.9 5.9 1.2 3.9 8.9 0.5 0.0 0.3 1.6 4.2 5.7 3.8 11.8 0.9 2.6 1.0 6.3 0.0 7.5 10.4 1.7 1.7 4.0 1.8 27.7 10.6 44.2 15.5 10.9 16.3 22.7 17.5 16.4 8.8 20.9 25.3 19.4 45.3 14.4 10.5 7.2 21.7 21.0 3.8 5.2 3.1 4.9 3.5 3.3 6.4 3.6 6.0 4.9 TAP2 "ABCB3, D6S217E, PSF2, RING11" ENSG00000204267 "Transporter 2, ATP binding cassette subfamily B member" Q03519 6 32821833-32838780 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 28.3;U-251 MG: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA001312 Approved Approved "Nuclear speckles,Endoplasmic reticulum" 14000 "Endoplasmic reticulum" "Nuclear speckles" "HPA001312: AB_1080206" "unprognostic (2.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-2)" "prognostic unfavourable (1.51e-4)" "unprognostic (1.90e-1)" "prognostic unfavourable (5.22e-8)" "unprognostic (5.32e-1)" "unprognostic (4.17e-2)" "unprognostic (2.35e-1)" "unprognostic (4.71e-2)" 12.8 8.4 6.5 22.5 6.9 14.7 9.5 6.3 7.3 8.8 15.0 7.6 3.3 15.3 9.6 5.9 17.4 7.9 11.5 7.7 5.2 6.0 10.8 19.0 18.0 14.0 7.1 6.3 9.7 6.1 2.6 5.8 5.7 7.9 8.2 11.9 7.9 12.1 5.2 5.8 9.6 28.0 7.0 6.1 24.9 7.7 3.3 6.9 25.9 14.7 7.1 20.1 23.6 10.7 0.9 2.8 4.9 5.4 2.9 4.1 1.9 7.8 0.0 0.0 2.3 2.2 3.0 0.0 0.5 1.6 6.2 8.4 2.1 16.1 15.4 3.0 3.9 8.2 7.1 28.3 2.4 10.4 0.9 1.8 6.0 0.7 1.0 0.0 12.2 0.3 0.4 8.4 13.0 4.0 8.5 5.2 0.0 0.6 2.0 1.0 0.3 3.9 8.4 0.0 5.9 5.2 0.1 0.1 0.0 7.6 16.2 1.6 0.8 0.0 2.3 8.7 2.0 2.3 28.0 8.0 13.3 14.4 8.0 10.8 1.5 1.7 2.0 1.8 4.1 5.4 2.0 0.9 1.2 2.7 2.0 0.6 1.0 0.6 4.9 2.9 4.1 2.8 1.9 1.9 6.5 6.9 6.3 7.3 5.2 6.0 7.1 6.3 7.9 6.9 TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" P01137 19 41301587-41353911 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 7.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" 1288167 38000000 "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavourable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavourable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" 24.3 14.4 7.7 29.8 11.9 53.1 19.0 2.2 8.2 27.8 15.3 14.3 11.5 11.4 24.1 12.8 24.5 13.0 15.6 17.6 8.8 6.5 19.2 10.4 32.4 33.3 12.0 4.1 15.3 8.2 6.9 9.7 54.7 11.7 17.2 5.8 10.3 10.9 15.9 8.7 14.0 17.6 14.6 12.8 55.8 12.8 9.5 12.3 30.6 10.3 9.1 30.6 28.7 24.6 0.7 1.4 7.5 2.2 0.5 1.7 1.3 14.5 22.9 1.2 0.1 10.6 9.4 2.9 21.1 19.0 6.8 4.6 9.7 9.0 14.4 22.7 28.6 7.9 4.1 13.5 2.4 19.1 4.5 48.5 5.5 12.3 13.7 13.3 33.1 12.2 4.3 13.1 8.4 34.1 26.0 36.3 6.2 10.7 11.4 19.5 2.5 13.7 12.3 3.2 21.6 12.1 6.3 0.2 1.6 5.8 0.3 4.1 0.5 11.9 43.1 26.7 20.9 5.6 22.9 20.1 7.8 9.4 26.1 26.7 4.7 1.5 1.9 7.5 1.7 2.2 1.3 0.4 0.9 0.9 1.4 0.7 0.7 0.9 4.7 0.5 2.0 1.4 0.5 1.3 7.7 11.9 2.2 7.6 8.8 6.5 12.0 4.1 11.7 12.3 TMEM219 IGFBP-3R ENSG00000149932 "Transmembrane protein 219" Q86XT9 16 29940885-29973052 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059185 Approved "HPA059185: " "unprognostic (4.13e-2)" "unprognostic (1.94e-3)" "unprognostic (1.51e-1)" "prognostic favourable (5.79e-4)" "unprognostic (2.62e-1)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (9.83e-2)" "unprognostic (8.53e-2)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-3)" 33.0 35.9 49.0 27.8 47.1 22.0 69.7 17.1 31.3 33.9 43.1 25.4 54.5 39.9 24.4 54.0 32.4 43.5 46.9 48.1 38.4 32.2 35.0 37.1 71.9 50.7 41.3 24.8 28.3 59.2 31.9 23.3 18.7 26.8 31.6 27.9 25.8 61.1 71.3 25.8 26.5 55.9 28.3 41.3 29.2 32.8 46.8 24.8 20.1 33.5 22.1 22.2 24.9 37.4 41.9 58.3 83.8 66.2 23.6 46.1 56.3 14.3 16.9 14.9 19.0 40.4 41.4 17.5 15.0 30.2 22.2 29.3 8.3 42.6 12.4 28.5 36.0 8.5 8.2 20.8 9.8 19.8 16.9 11.1 13.1 26.8 47.0 7.1 28.0 38.0 30.7 15.7 12.9 35.0 7.4 23.8 27.7 15.0 10.3 23.1 8.9 11.5 19.9 9.5 26.0 38.3 9.2 8.6 17.3 5.2 10.3 26.3 17.2 27.0 20.0 18.0 11.0 9.1 6.9 19.1 6.5 9.9 24.1 25.4 15.0 71.8 66.2 83.8 30.5 47.5 31.1 41.9 43.2 31.6 53.6 40.2 41.0 31.8 31.3 23.6 34.2 58.3 46.1 56.3 49.0 47.1 17.1 31.3 38.4 32.2 41.3 24.8 26.8 24.8 WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved "HPA029128: AB_10603460" "unprognostic (4.27e-2)" "unprognostic (5.05e-2)" "unprognostic (1.58e-1)" "prognostic favourable (1.13e-6)" "unprognostic (7.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-2)" "unprognostic (6.97e-3)" "unprognostic (2.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.36e-3)" "unprognostic (5.33e-3)" "unprognostic (6.20e-2)" "unprognostic (5.02e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (3.13e-4)" "unprognostic (3.64e-2)" 28.5 13.3 17.9 7.0 52.5 1.5 16.5 9.4 24.2 22.3 15.5 13.2 21.9 12.0 31.2 15.1 12.1 28.9 24.0 27.8 19.4 12.2 7.1 7.6 30.2 7.4 13.5 16.5 51.0 12.4 8.8 20.7 25.4 13.6 22.6 4.5 16.6 12.1 39.0 10.3 10.0 11.1 28.1 14.2 16.9 12.5 18.3 14.9 1.3 23.4 4.4 3.2 24.2 12.2 4.4 0.6 0.0 1.6 2.5 6.9 2.4 5.3 10.9 3.7 13.3 15.2 4.0 40.1 9.5 12.5 6.5 5.7 9.4 14.6 2.4 14.0 10.2 2.4 2.7 5.3 2.7 2.1 5.5 0.0 4.8 29.0 13.6 0.0 0.4 13.5 7.5 5.6 5.3 10.0 0.1 9.8 3.8 9.9 0.4 0.1 5.2 15.5 1.2 3.7 2.7 2.6 23.2 2.3 6.2 5.5 6.8 5.1 11.9 0.1 8.2 7.5 9.7 7.3 5.7 10.8 3.5 0.0 9.5 0.0 7.5 0.0 1.0 0.0 4.9 1.6 6.9 4.4 2.6 3.5 0.3 2.3 2.3 2.8 0.0 2.5 1.6 0.6 1.3 2.4 17.9 52.5 9.4 24.2 19.4 12.2 13.5 16.5 13.6 14.9 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978453-48981676 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease mutation, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 7.7;brain: 6.5;placenta: 17.5" "Cell line enhanced" "Detected in single" "CACO-2: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "basal ganglia: 6.5;cerebral cortex: 1.8" "Group enriched" "Detected in some" 8 "gdT-cell: 5.3;MAIT T-cell: 7.7;memory CD4 T-cell: 3.0;memory CD8 T-cell: 4.8;naive CD8 T-cell: 3.2" "Lineage enriched" "Detected in single" 24 "T-cells: 7.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebral cortex: 1.3;hippocampal formation: 1.5;midbrain: 3.5;olfactory region: 2.1" "Secreted to extracellular matrix" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.3 0.1 0.4 1.5 6.5 2.3 0.3 0.3 2.9 0.3 0.3 0.3 0.3 1.5 0.3 0.3 0.5 0.1 0.7 0.3 0.6 0.5 0.3 0.3 0.7 2.9 0.3 0.3 0.3 0.3 0.0 0.3 17.5 0.3 0.3 0.0 0.3 1.2 0.3 0.3 0.0 1.8 0.3 0.3 1.9 1.2 1.4 0.3 0.3 0.3 0.3 0.3 0.6 0.3 0.3 0.0 0.0 0.0 0.0 7.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.7 0.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 7.7 0.3 3.0 4.8 0.0 0.0 0.5 3.2 0.0 0.0 0.0 0.0 0.4 0.8 0.4 6.5 0.3 1.8 0.6 0.5 0.3 0.3 0.3 0.3 YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944461-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 154.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025918, HPA061603" Uncertain Approved Nucleoli,Cytosol 130000000 Cytosol Nucleoli "CAB025918: , HPA061603: " "unprognostic (3.77e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-2)" "unprognostic (1.86e-2)" "unprognostic (1.13e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (1.59e-5)" "unprognostic (8.62e-2)" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-1)" "unprognostic (5.60e-2)" "unprognostic (7.00e-2)" "unprognostic (6.81e-2)" 21.5 18.6 87.9 20.6 47.4 16.3 19.3 41.9 154.3 13.7 24.4 10.0 4.3 17.2 13.1 14.1 14.0 16.4 18.6 15.2 78.8 59.1 11.7 11.5 25.0 13.5 35.5 101.6 10.0 16.7 5.2 10.4 22.4 49.5 12.3 20.1 6.8 9.9 15.6 13.9 9.9 17.4 25.9 19.4 12.8 26.9 3.7 9.1 6.3 10.5 5.5 15.1 18.5 10.6 8.1 16.6 14.9 14.4 17.7 12.8 9.6 67.9 27.2 30.4 17.7 18.5 17.1 19.3 66.1 32.7 38.1 43.6 28.8 23.7 40.1 16.1 60.6 32.9 36.4 36.3 36.0 35.5 31.7 23.7 21.4 25.7 18.7 76.3 26.5 15.5 19.4 32.1 22.9 31.1 32.7 29.4 29.0 27.4 23.1 35.1 36.2 29.8 33.2 41.9 21.3 24.0 29.4 65.4 21.5 37.6 26.3 23.5 15.0 18.9 49.7 38.5 38.5 28.2 41.9 16.4 25.3 50.2 27.9 30.8 33.8 7.8 14.4 14.9 5.7 11.8 8.1 8.1 7.0 8.1 16.6 7.6 2.8 3.6 8.7 17.7 12.2 4.5 12.8 9.6 87.9 47.4 41.9 126.3 78.8 59.1 35.5 101.6 49.5 9.1 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087323 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 19.6;MOLT-4: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA055995: " "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favourable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 14.4 5.2 8.0 3.0 16.6 3.4 13.0 6.7 10.8 10.5 6.9 20.5 6.4 5.7 15.8 12.7 3.8 10.6 5.3 6.5 9.5 6.2 18.0 16.2 7.3 3.3 22.7 7.2 12.2 10.9 13.9 9.0 3.6 9.5 7.8 6.5 8.3 8.3 10.3 3.7 3.9 5.0 13.0 10.5 5.0 8.7 4.0 13.7 5.2 16.4 1.6 2.8 5.4 5.8 0.2 1.8 0.3 1.1 0.1 0.8 0.2 3.3 2.7 3.6 19.6 15.0 1.0 0.2 1.1 3.3 1.7 4.6 5.8 1.6 0.0 7.3 2.2 0.4 1.9 1.2 1.5 1.1 3.6 2.6 5.9 6.6 9.0 3.5 1.0 16.8 4.5 0.8 3.4 5.5 0.0 7.3 1.0 3.3 18.5 0.5 2.3 1.6 7.7 6.8 1.0 8.1 1.2 3.9 8.3 3.9 3.3 5.6 4.9 2.4 2.2 1.5 3.0 3.4 4.5 5.3 5.0 7.5 2.4 6.7 3.5 0.0 1.1 0.3 0.4 0.4 0.4 0.1 0.3 0.5 0.9 0.2 0.8 0.8 0.3 0.1 0.1 1.8 0.0 0.2 8.0 16.6 6.7 10.8 9.5 6.2 22.7 7.2 9.5 13.7