Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904943-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;lymphoid tissue: 16.5" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 19.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065887 Supported Supported "Secreted in other tissues" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favourable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 2.1 0.5 2.5 16.5 7.7 0.1 1.6 2.1 12.5 3.4 2.6 0.8 0.0 0.1 4.0 0.1 2.2 0.5 12.3 1.0 1.2 18.4 0.6 0.3 1.7 1.6 2.8 6.2 0.2 7.7 0.1 4.5 0.3 33.8 1.4 1.4 2.5 2.2 1.0 0.3 0.9 1.3 1.5 5.9 0.2 1.8 3.6 0.2 0.1 0.3 0.0 1.4 3.1 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 7.7 2.1 12.1 1.2 18.4 2.8 6.2 33.8 0.2 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058242-131089883 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 58.4;brain: 25.5;pituitary gland: 50.3" "Cell line enriched" "Detected in single" 164 "SH-SY5Y: 62.9" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Region enriched" "Detected in many" 5 "hypothalamus: 25.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 104.3" "Group enriched" "Detected in many" 5 "basal ganglia: 19.8;hypothalamus: 57.8;midbrain: 27.1;pons and medulla: 20.1" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 6.9 58.4 1.4 0.2 3.6 0.1 1.0 0.0 2.7 0.5 0.2 0.0 0.0 0.1 0.1 2.0 0.3 0.2 0.2 0.1 1.0 25.5 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.1 0.1 50.3 0.3 5.4 0.3 0.2 0.6 0.2 0.2 13.7 0.1 0.1 0.1 0.8 0.1 0.2 0.6 0.0 0.5 0.5 4.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 62.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.6 0.0 0.4 1.0 25.5 0.5 0.0 5.4 0.0 AVPR1B AVPR3 ENSG00000198049 "Arginine vasopressin receptor 1B" P47901 1 206109692-206117699 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 23 "pituitary gland: 52.8" "Cell line enhanced" "Detected in single" "PC-3: 3.5" "Cancer enhanced" "Detected in some" "renal cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075404 Enhanced "HPA075404: " "unprognostic (4.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.82e-1)" "unprognostic (2.82e-1)" "unprognostic (2.87e-1)" "unprognostic (1.08e-2)" "unprognostic (3.33e-1)" "unprognostic (2.96e-2)" "unprognostic (6.23e-2)" "unprognostic (7.65e-2)" "unprognostic (1.86e-1)" "unprognostic (6.66e-3)" 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.6 0.5 0.1 1.3 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 52.8 0.1 0.1 0.2 0.8 0.0 0.0 0.4 0.0 0.0 1.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.9 3.5 0.0 0.0 0.2 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621818 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044185, HPA051937" Approved Supported "Cell Junctions,Midbody ring,Centriolar satellite,Cytosol" "Centriolar satellite" "Cell Junctions, Midbody ring, Cytosol" "HPA044185: AB_10965852, HPA051937: " "unprognostic (2.28e-2)" "unprognostic (7.74e-2)" "unprognostic (7.37e-2)" "unprognostic (2.90e-1)" "unprognostic (5.28e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.68e-3)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-3)" "unprognostic (5.48e-3)" "unprognostic (6.85e-3)" "unprognostic (1.81e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-1)" "unprognostic (6.81e-3)" 8.4 7.5 9.3 7.6 11.7 6.5 12.0 31.0 15.1 11.7 11.0 9.6 7.6 5.9 12.7 12.7 6.7 12.9 7.6 8.4 9.8 6.4 9.2 4.6 7.7 10.1 10.8 10.6 14.7 7.1 10.1 32.9 7.6 11.0 9.7 9.4 7.8 9.1 10.9 11.9 5.7 7.7 11.1 11.2 8.7 8.0 8.6 12.9 11.9 12.1 5.7 10.2 11.0 9.7 2.6 1.1 7.0 2.2 5.0 14.1 2.7 5.4 1.9 6.1 3.6 9.2 5.4 4.8 7.0 6.4 9.2 8.1 4.2 4.3 15.2 1.6 3.7 3.0 3.4 6.4 10.3 5.4 4.1 9.5 8.4 4.8 6.5 12.1 3.6 5.3 9.3 7.6 5.4 5.8 8.8 2.4 7.1 4.4 9.7 7.7 9.9 7.5 3.3 5.2 8.2 5.5 1.9 2.3 4.2 8.4 5.4 5.1 1.9 5.3 3.1 6.9 5.4 6.4 9.5 4.9 5.2 8.1 5.1 13.9 5.4 7.0 1.5 3.3 4.3 1.9 5.6 2.6 7.4 5.3 1.1 1.7 8.6 6.2 0.3 5.0 2.2 1.0 14.1 2.7 9.3 11.7 31.0 15.1 9.8 6.4 10.8 10.6 11.0 12.9 CGA "FSHA, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095406 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 62 "pituitary gland: 398.8;placenta: 489.3" "Cell line enriched" "Detected in some" 19 "BEWO: 105.3" "Cancer enhanced" "Detected in many" "testis cancer: 13.0" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "hypothalamus: 69.2" "CAB023350, HPA029698" Enhanced "Secreted to blood" "CAB023350: AB_617281, HPA029698: " "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (3.22e-5)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.17e-1)" "unprognostic (7.04e-3)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (8.32e-2)" "unprognostic (9.15e-3)" 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 398.8 489.3 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.6 0.0 0.1 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.2 1.9 3.5 1.5 1.1 2.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 105.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 2.3 1.1 1.0 1.7 0.5 0.7 1.3 0.8 1.4 0.6 2.2 1.2 2.1 3.5 1.1 1.5 1.9 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911430-5925361 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 424.9;pituitary gland: 177.5" "Group enriched" "Detected in some" 23 "SCLC-21H: 65.1;SH-SY5Y: 99.7" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 2.6;T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" 24000000 Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavourable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favourable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 3.4 424.9 8.2 1.4 10.2 0.8 1.0 82.5 16.4 0.8 3.0 2.1 1.2 7.7 0.9 1.3 0.8 2.5 0.8 7.6 20.7 15.4 1.7 0.7 1.0 1.1 7.2 9.1 3.0 17.0 0.8 177.5 0.8 51.8 5.6 2.5 0.7 0.9 1.2 2.1 0.9 4.4 0.9 2.3 0.8 19.7 2.4 0.8 0.0 1.9 0.4 0.9 0.8 0.1 0.0 0.6 0.0 0.0 0.0 2.6 0.2 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 65.1 99.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.4 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.2 8.2 10.2 82.5 16.4 20.7 15.4 7.2 9.1 51.8 0.8 CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470998-40474571 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved Vesicles Vesicles "HPA057697: , HPA071601: " "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" 10.3 7.9 7.1 7.5 6.9 2.3 22.7 6.5 7.4 14.9 7.9 6.0 13.8 3.6 17.5 11.1 6.5 12.3 14.1 12.6 5.5 2.9 8.1 9.6 15.9 20.9 8.1 4.5 18.8 11.6 10.2 11.4 22.4 7.1 10.7 3.8 9.8 12.7 17.2 5.5 6.8 7.1 13.3 5.9 10.5 7.3 9.2 6.3 7.5 12.4 8.3 6.1 12.1 18.2 2.1 3.4 8.0 1.9 5.5 4.0 1.1 11.0 7.3 11.7 31.6 18.4 14.3 18.3 10.9 20.8 19.4 18.4 8.8 5.6 1.8 16.7 18.5 19.1 10.4 6.1 9.1 13.2 6.1 5.7 7.8 8.4 10.0 2.4 14.8 17.4 5.1 6.8 5.2 17.0 5.5 6.6 14.4 8.4 4.0 12.7 7.5 8.5 11.1 14.9 3.2 13.0 5.7 8.5 13.0 9.6 10.8 3.6 15.7 10.2 13.8 32.9 12.2 10.3 10.8 13.4 9.2 5.1 14.8 8.4 23.6 8.0 1.9 3.6 4.0 1.9 1.1 0.5 2.0 3.4 3.4 2.1 1.8 1.4 0.3 5.5 0.9 1.2 1.3 1.1 7.1 6.9 6.5 7.4 5.5 2.9 8.1 4.5 7.1 6.3 CHST8 GALNAC-4-ST1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621955-33773509 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.1;pituitary gland: 36.7" "Group enriched" "Detected in some" 4 "RPMI-8226: 18.4;SCLC-21H: 10.7;SH-SY5Y: 18.5" "Cancer enhanced" "Detected in many" "glioma: 4.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016004 Enhanced "Intracellular and membrane" "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" 2.0 3.8 3.6 1.7 2.8 0.4 7.0 16.6 9.2 3.4 1.1 1.0 0.0 0.5 1.3 0.4 0.7 2.0 4.0 0.8 9.2 7.9 0.5 0.7 0.6 2.0 5.3 1.5 1.4 3.4 0.4 36.7 0.4 27.1 1.8 0.5 1.4 0.7 0.8 0.6 0.9 0.8 0.8 7.2 3.3 0.9 2.9 0.9 0.0 0.6 0.3 1.4 0.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.1 0.0 0.0 0.0 1.2 0.0 3.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.9 0.0 0.0 0.1 18.4 0.0 0.3 10.7 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.6 2.8 16.6 9.2 9.2 7.9 5.3 1.5 27.1 0.9 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5" "Group enriched" "Detected in some" 7 "ASC diff: 39.4;HSkMC: 26.0" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 6 "B-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported "Plasma membrane,Actin filaments" "Plasma membrane" "Actin filaments" "HPA042256: , HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 19.4 6.4 18.0 5.2 15.8 1.5 14.9 13.8 30.5 3.9 5.5 0.8 0.8 2.3 3.1 4.7 3.7 5.5 3.6 1.4 17.6 7.7 0.9 0.7 6.4 6.5 2.3 14.7 4.1 1.8 1.3 18.3 5.2 4.2 1.5 5.1 0.0 4.3 4.0 1.7 2.4 4.2 5.8 3.2 2.3 2.3 2.7 2.8 0.0 2.6 0.0 9.9 2.7 3.1 2.9 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 39.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.8 1.3 0.0 2.6 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 3.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 18.0 15.8 13.8 21.4 17.6 7.7 2.3 14.7 4.2 2.8 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914006 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 46.5" "Cell line enhanced" "Detected in some" "HDLM-2: 23.4;RT4: 9.9;SCLC-21H: 6.7;U-2 OS: 5.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavourable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavourable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 12.0 0.2 1.3 1.1 0.0 0.1 6.8 1.1 1.3 0.7 1.4 10.8 0.3 2.4 1.9 0.2 0.5 0.4 0.2 0.3 0.8 2.8 0.1 0.1 0.5 0.3 0.0 0.3 0.2 1.7 46.5 0.0 1.9 4.7 0.1 1.6 0.8 5.1 0.5 0.1 0.4 2.2 1.8 0.3 3.7 0.8 0.1 1.4 0.3 0.7 1.7 1.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.9 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 6.8 0.3 0.3 0.8 0.3 0.0 1.9 0.1 CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784280-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 23.2;pituitary gland: 16.5" "Group enriched" "Detected in some" 4 "RT4: 7.9;SH-SY5Y: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB025251 Enhanced "Intracellular and membrane" "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" 0.8 0.6 14.7 0.5 5.1 0.5 1.5 23.2 11.5 1.4 0.6 1.1 0.0 0.8 2.7 1.1 0.5 1.6 0.7 0.5 3.2 2.2 0.6 0.5 0.6 0.5 1.8 5.2 0.6 0.5 0.6 16.5 0.6 2.9 1.3 0.6 1.9 1.2 2.5 0.6 1.4 1.0 1.2 1.0 0.5 0.5 1.0 2.8 0.0 0.9 0.0 0.5 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 1.6 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 5.1 23.2 11.5 3.2 2.2 1.8 5.2 2.9 2.8 CSH1 "CSA, CSMT, FLJ75407, hCS-A, PL" ENSG00000136488 "Chorionic somatomammotropin hormone 1" P0DML2 17 63894909-63896661 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "placenta: 450.4" "Cell line enriched" "Detected in some" 8 "BEWO: 15.9" "Cancer enriched" "Detected in single" 8 "testis cancer: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026374, HPA043715" Enhanced "Secreted to blood" "CAB026374: , HPA043715: " "unprognostic (6.99e-2)" 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 15.7 450.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 1.9 0.1 1.0 0.9 0.8 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 CSH2 "CS-2, CSB, hCS-B" ENSG00000213218 "Chorionic somatomammotropin hormone 2" P0DML3 17 63872012-63873766 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "placenta: 246.2" "Cell line enriched" "Detected in single" 20 "BEWO: 13.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" "HPA043715: " "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (1.86e-1)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 246.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.4 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSHL1 "CS-5, CSHP1, CSL, hCS-L, MGC149868" ENSG00000204414 "Chorionic somatomammotropin hormone like 1" Q14406 17 63909597-63918838 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 864 "pituitary gland: 334.1;placenta: 293.7" "Cell line enhanced" "Detected in some" "MCF7: 1.3;SCLC-21H: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025646, HPA043715" Enhanced "Secreted to blood" "CAB025646: , HPA043715: " 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 334.1 293.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 DLK1 "Delta1, FA1, pG2, Pref-1, ZOG" ENSG00000185559 "Delta like non-canonical Notch ligand 1" P80370 14 100725705-100738224 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 157.6;pituitary gland: 143.1;placenta: 244.9" "Group enriched" "Detected in some" 6 "AF22: 22.5;Hep G2: 75.2;SH-SY5Y: 89.6" "Cancer enhanced" "Detected in many" "liver cancer: 28.1" "Group enriched" "Detected in some" 5 "hypothalamus: 2.6;pons and medulla: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 65.4" "Region enhanced" "Detected in many" "midbrain: 159.6" "CAB005872, HPA062262" Enhanced Approved "Golgi apparatus" 160000 "Golgi apparatus" "CAB005872: AB_731965, HPA062262: " "unprognostic (2.16e-2)" "prognostic unfavourable (2.31e-4)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (4.89e-3)" "unprognostic (5.75e-2)" "unprognostic (1.87e-2)" "unprognostic (1.12e-1)" "unprognostic (5.24e-1)" "unprognostic (3.11e-2)" "unprognostic (6.57e-2)" 0.3 157.6 0.2 0.7 0.8 0.0 0.9 0.0 0.1 0.5 0.0 1.8 0.2 0.2 0.2 4.4 0.3 0.3 0.8 2.7 0.1 2.6 0.1 0.1 0.1 0.1 0.8 0.0 34.9 4.6 0.0 143.1 244.9 6.0 0.2 0.0 0.2 8.2 0.0 2.0 0.1 0.2 0.2 0.3 0.2 0.2 14.2 0.0 0.5 0.0 10.0 1.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 75.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 6.3 89.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.2 0.8 0.0 0.0 0.1 2.6 0.8 0.0 6.0 0.0 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490318 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 22.9;pituitary gland: 42.3" "Cell line enhanced" "Detected in many" "AF22: 15.4;Karpas-707: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 11.5" "Lineage enriched" "Detected in many" 8 "dendritic cells: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: , HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favourable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.9 2.3 7.3 1.3 17.6 2.6 3.4 15.8 9.9 5.4 2.0 1.1 7.6 2.6 1.8 22.9 1.1 5.7 2.1 2.0 4.2 6.8 4.0 7.2 1.9 1.5 4.4 7.5 1.2 6.3 7.2 42.3 1.0 6.3 4.3 2.6 4.6 5.9 7.3 1.1 0.8 3.8 1.2 2.1 1.7 2.7 4.8 1.4 0.0 8.7 0.2 3.3 1.9 1.1 0.6 11.5 1.4 0.3 0.1 0.5 0.2 12.0 2.5 15.4 6.0 0.4 0.0 0.4 0.1 0.6 2.4 4.5 2.4 3.6 4.6 5.6 0.1 4.1 1.7 2.5 2.3 1.8 2.9 2.2 0.2 1.3 0.3 2.6 1.6 0.2 8.3 0.6 2.5 0.0 0.8 17.8 1.0 4.1 0.3 3.6 3.3 3.5 0.1 3.6 7.1 3.2 2.1 10.0 4.2 0.3 2.5 6.7 10.7 4.5 0.5 1.3 4.7 2.7 2.2 3.9 3.4 3.9 5.2 0.6 2.7 0.5 0.3 0.1 0.2 0.2 0.5 0.4 0.4 0.3 0.9 0.6 0.2 0.3 1.4 0.1 0.2 11.5 0.3 0.2 7.3 17.6 15.8 9.9 4.2 6.8 4.4 7.5 6.3 1.4 FSHB ENSG00000131808 "Follicle stimulating hormone beta subunit" P01225 11 30231016-30235261 "Cancer-related genes, Disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "pituitary gland: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB023410, HPA069703" Enhanced "Secreted to blood" 47000 "CAB023410: AB_324983, HPA069703: " "unprognostic (1.04e-1)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 70.7 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.5 0.0 0.0 0.3 0.3 0.0 FST FS ENSG00000134363 Follistatin P19883 5 53480409-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 58.2;HaCaT: 49.3;HBEC3-KT: 31.5;HMC-1: 35.4;PC-3: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.0;naive CD4 T-cell: 2.0;non-classical monocyte: 1.0" "Group enriched" "Detected in many" 5 "monocytes: 1.0;T-cells: 2.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB026025 Approved "Secreted to blood" 1800000 "CAB026025: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavourable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 12.4 3.2 2.0 3.1 0.8 0.1 7.1 0.2 0.7 3.5 5.2 0.3 1.1 0.9 2.3 9.5 3.6 4.9 4.1 5.6 1.0 1.0 1.7 42.7 4.3 0.8 0.4 0.6 20.7 19.4 0.0 2.9 13.5 1.0 9.3 1.7 5.7 5.5 6.5 12.6 9.0 4.3 3.7 0.4 0.2 4.8 4.9 0.5 1.2 2.0 6.7 7.1 6.2 13.8 0.1 0.2 0.0 1.0 0.0 2.0 0.1 3.2 0.3 5.8 0.0 6.6 2.3 9.6 12.7 58.2 7.8 7.7 0.0 0.0 0.0 0.1 3.3 49.3 0.0 31.5 5.6 0.1 0.0 0.6 0.2 5.2 3.5 0.0 35.4 5.4 0.0 14.4 9.4 6.6 0.0 0.1 4.9 0.0 0.0 0.2 8.9 95.2 0.6 7.4 0.0 0.0 5.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 21.6 6.2 2.2 1.8 0.0 0.0 0.0 2.5 0.6 19.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.2 0.1 2.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.0 0.8 0.2 0.7 1.0 1.0 0.4 0.6 1.0 0.5 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "pituitary gland: 149.9" "Cell line enhanced" "Detected in some" "CACO-2: 46.9;HEK 293: 21.9;K-562: 24.3;NB-4: 86.7;SH-SY5Y: 35.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "hypothalamus: 18.8" "Cell type enriched" "Detected in single" 15 "intermediate monocyte: 1.5" "Lineage enriched" "Detected in single" 15 "monocytes: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 111.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" 60030 "Golgi apparatus" Vesicles "CAB079779: , HPA049864: " "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavourable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 2.8 0.2 0.1 14.8 0.5 0.4 4.5 0.6 2.0 0.2 6.0 0.1 0.4 1.7 0.2 0.7 0.7 0.2 0.3 0.6 1.3 18.8 0.3 0.2 0.2 0.1 0.2 0.6 0.2 2.9 0.0 149.9 0.9 2.2 0.7 4.1 0.6 0.5 1.8 0.3 4.5 2.2 9.7 0.3 0.2 1.5 0.5 0.4 0.7 0.2 0.4 0.3 1.5 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 4.4 6.6 0.0 0.1 0.0 46.9 1.7 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 21.9 1.1 14.1 0.0 0.2 0.6 0.0 0.3 0.7 0.0 0.0 1.1 24.3 0.0 0.0 13.3 0.0 86.7 11.2 4.2 0.0 0.0 8.9 0.1 0.0 9.1 35.0 4.6 0.2 0.0 0.2 10.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.7 1.3 18.8 0.2 0.6 2.2 0.4 GATA2 NFE1B ENSG00000179348 "GATA binding protein 2" P23769 3 128479427-128493185 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Phagocytosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 81.2;ductus deferens: 85.8;seminal vesicle: 209.1" "Cell line enhanced" "Detected in many" "BEWO: 55.8;HEL: 68.8;HMC-1: 37.2;SH-SY5Y: 65.0" "Cancer enhanced" "Detected in all" "prostate cancer: 36.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 339 "basophil: 81.2" "Lineage enriched" "Detected in single" 813 "granulocytes: 81.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005633, CAB024847" Enhanced Supported Nucleoplasm Nucleoplasm "CAB024847: , HPA005633: AB_1078954" "unprognostic (1.71e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (8.61e-2)" "unprognostic (8.67e-2)" "unprognostic (4.17e-2)" "unprognostic (5.96e-3)" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.12e-2)" "unprognostic (3.58e-2)" "unprognostic (3.04e-1)" "prognostic favourable (2.04e-4)" "unprognostic (2.50e-1)" "unprognostic (8.07e-2)" "unprognostic (2.08e-1)" "prognostic favourable (5.22e-5)" 7.0 6.2 2.1 1.5 2.4 2.5 7.9 1.2 1.9 22.4 2.8 1.4 85.8 2.5 20.6 5.4 3.2 23.0 9.7 4.8 1.5 1.0 7.6 0.6 16.1 2.2 1.8 1.1 4.6 5.8 3.4 4.5 51.8 2.4 27.8 1.8 6.1 1.9 209.1 3.5 4.1 3.4 8.4 1.4 5.1 2.9 2.7 1.5 0.4 3.3 2.7 1.5 22.4 12.4 0.0 0.0 81.2 0.0 0.0 0.0 0.4 4.6 1.1 0.2 3.1 0.4 0.1 55.8 10.4 8.9 3.6 1.3 1.9 2.0 0.1 2.9 6.1 4.9 2.9 0.0 1.5 0.0 1.6 68.8 7.6 3.0 0.8 6.9 37.2 0.0 0.0 0.1 0.0 5.6 18.0 0.1 0.0 1.7 0.0 14.1 0.2 0.3 0.0 1.3 0.0 0.1 4.1 4.3 65.0 2.6 13.8 0.4 2.6 2.8 10.0 0.2 0.1 2.5 1.4 0.0 0.0 0.0 0.1 0.4 0.7 81.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 2.4 1.2 1.9 1.5 1.0 1.8 1.1 2.4 1.5 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918838 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 994.5" "Cell line enriched" "Detected in some" 5 "U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.1;T-reg: 2.2" "Group enriched" "Detected in many" 4 "B-cells: 2.1;T-cells: 2.2" HPA043715 Supported "Secreted to blood" 1735000 180000 "HPA043715: " "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 0.3 0.0 0.0 0.5 0.0 1.1 0.2 0.1 0.1 0.4 0.4 0.0 0.0 3.3 1.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.0 0.0 0.0 0.3 994.5 217.7 0.1 0.2 0.5 0.0 0.1 0.2 0.8 0.9 0.4 0.1 0.0 1.6 0.3 0.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.0 0.5 0.0 2.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.5 7.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.5 0.0 2.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881935 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 309 "pituitary gland: 47.3;placenta: 138.4" "Cell line enriched" "Detected in single" 20 "BEWO: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" "HPA043715: " "unprognostic (1.02e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 138.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67739328-67754360 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "pituitary gland: 56.6" "Cell line enhanced" "Detected in some" "K-562: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA013424 Enhanced "HPA013424: " "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.78e-1)" "unprognostic (4.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.63e-1)" "unprognostic (9.03e-2)" "unprognostic (3.23e-2)" "unprognostic (9.67e-2)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" 0.1 3.9 0.1 0.4 0.2 0.2 0.1 0.3 1.7 0.3 0.1 0.1 0.1 0.7 0.1 0.1 1.6 0.0 0.2 0.2 0.2 0.2 0.1 0.1 0.1 1.1 0.1 0.1 0.2 0.3 0.0 56.6 0.1 0.5 0.2 0.0 0.1 0.3 0.1 0.2 0.9 0.1 0.1 0.1 0.2 0.3 0.3 0.1 0.2 1.0 0.1 0.4 0.1 0.5 1.3 0.2 0.0 0.0 0.4 0.3 0.0 0.2 1.5 1.5 1.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.5 1.7 1.2 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.5 0.2 0.3 0.7 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.7 0.6 0.4 0.9 0.0 0.6 1.2 0.6 0.0 0.0 0.8 2.0 0.0 0.3 0.0 0.3 0.2 1.0 0.1 0.2 0.6 0.2 1.1 0.3 0.6 1.4 0.8 0.9 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.1 0.0 0.0 1.3 0.1 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.1 0.5 0.1 GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176653-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pituitary gland: 64.9" "Cell line enriched" "Detected in some" 8 "HEK 293: 10.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "hypothalamus: 16.8" "Region enriched" "Detected in single" 9 "hypothalamus: 6.4" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA049862: , HPA054678: " "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.3 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 64.9 3.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.6 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 138.7" "Group enriched" "Detected in some" 5 "Hep G2: 23.0;SH-SY5Y: 20.7" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" 430000 Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavourable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 0.8 11.9 1.4 0.4 5.3 0.0 2.7 0.6 6.2 2.7 0.5 3.3 1.2 0.2 1.1 1.5 1.3 1.6 0.8 5.6 3.3 15.4 0.5 1.5 0.2 0.0 3.8 1.9 1.0 1.7 0.0 138.7 0.6 4.7 3.9 0.2 2.2 2.0 6.4 0.3 0.6 0.4 3.2 2.7 0.2 0.5 11.8 1.9 0.2 5.3 0.8 0.5 0.6 0.5 0.6 0.4 1.5 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.1 0.0 0.0 1.2 0.0 0.0 4.0 0.3 0.0 1.7 23.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 1.9 20.7 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.6 0.0 2.3 0.7 0.3 0.0 0.0 0.0 0.0 1.5 0.3 0.2 0.2 0.1 0.2 0.3 0.3 0.3 0.1 0.6 0.3 0.2 1.2 0.3 0.1 0.4 0.3 0.2 1.4 5.3 0.6 2.3 3.3 15.4 3.8 1.9 4.7 1.9 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone beta polypeptide" P01229 19 49015980-49017081 "Cancer-related genes, Disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pituitary gland: 301.4" "Cell line enhanced" "Detected in many" "A549: 6.5;U-266/84: 7.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 1.8;T-reg: 1.3" "Lineage enriched" "Detected in single" 12 "T-cells: 1.8" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" Cytosol "CAB022241: , CAB022707: , HPA038925: " "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavourable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 3.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 23.1 0.0 301.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.5 0.5 0.1 0.1 0.1 0.5 1.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.1 1.3 6.5 0.2 1.3 0.0 0.0 1.8 0.5 0.0 1.0 0.5 5.3 1.9 1.7 0.1 0.0 0.5 0.0 0.4 0.0 1.7 5.1 0.3 1.7 2.5 0.3 0.4 1.7 0.0 0.0 0.3 0.0 0.3 4.7 2.8 0.3 0.3 0.1 0.6 0.7 0.5 2.8 1.1 1.3 0.0 1.3 3.0 1.2 1.9 0.4 2.2 2.0 0.0 0.0 2.6 2.7 0.3 3.3 2.4 7.0 1.8 1.3 3.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.1 MIA CD-RAP ENSG00000261857 "Melanoma inhibitory activity" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.1;breast: 28.7;pituitary gland: 33.5;salivary gland: 22.7;stomach 1: 28.9" "Group enriched" "Detected in some" 35 "AN3-CA: 21.3;CAPAN-2: 17.8;SK-MEL-30: 62.1;WM-115: 58.8" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Region enriched" "Detected in some" 8 "midbrain: 16.1" "Cell type enhanced" "Detected in some" "basophil: 1.6;neutrophil: 3.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.0" HPA042369 Approved "Secreted to blood" 8273333 "HPA042369: AB_10794420" "prognostic favourable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 0.7 1.5 0.6 3.5 0.6 1.4 28.7 0.9 0.4 3.7 6.1 0.5 2.2 0.8 2.8 3.2 4.0 1.0 3.2 4.1 0.4 0.4 0.9 0.8 1.4 0.7 16.1 0.4 2.6 0.4 0.0 33.5 0.9 2.1 2.2 1.9 6.0 22.7 1.7 0.8 4.5 2.2 3.4 3.1 2.4 28.9 1.0 0.4 0.5 1.1 5.9 4.4 2.0 1.5 0.7 0.0 3.0 0.1 0.0 0.3 0.1 0.0 0.1 0.2 21.3 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 62.1 0.1 0.2 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.0 0.1 58.8 1.6 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.1 0.0 0.0 0.1 0.6 0.6 0.9 0.4 0.4 0.4 16.1 0.4 2.1 0.4 MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806920 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease mutation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions" "Cell Junctions" "HPA063389: , HPA076180: , HPA077255: " "unprognostic (3.25e-2)" "unprognostic (8.19e-2)" "unprognostic (4.48e-2)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" "prognostic favourable (3.97e-5)" "prognostic unfavourable (1.19e-4)" "unprognostic (1.75e-2)" "unprognostic (2.85e-1)" "unprognostic (8.69e-2)" "prognostic favourable (4.81e-5)" "unprognostic (3.10e-1)" "prognostic favourable (2.12e-4)" "unprognostic (2.35e-3)" "unprognostic (2.94e-1)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" 11.7 11.0 8.9 10.3 12.4 24.5 9.7 15.3 15.8 9.0 10.4 13.5 8.3 10.7 10.4 54.5 11.3 12.7 10.9 23.4 9.2 8.6 12.0 12.4 16.2 13.3 9.9 10.7 28.8 11.2 6.7 17.5 6.6 10.7 10.2 9.1 14.1 7.3 7.2 15.3 13.2 13.6 10.9 7.4 18.3 13.6 10.6 10.9 10.2 15.8 9.8 11.7 10.4 17.9 4.9 3.2 4.7 7.4 3.4 4.7 2.3 1.3 5.8 6.7 7.7 6.7 10.3 1.1 4.1 8.7 3.9 3.4 5.3 8.5 11.2 2.3 4.2 2.6 4.8 3.9 1.7 5.3 4.3 8.2 7.3 1.5 9.0 4.5 10.7 9.0 4.0 3.0 3.2 6.1 26.9 7.4 4.0 1.8 4.9 2.1 2.2 2.1 5.1 3.7 12.4 6.3 7.0 6.6 11.4 5.1 5.0 8.0 7.9 7.1 5.4 3.9 3.3 4.6 1.0 4.1 5.6 20.9 4.8 10.4 3.6 1.1 3.8 1.9 4.7 7.4 1.8 3.0 1.6 2.5 3.2 4.9 2.4 2.7 4.7 3.4 6.9 1.5 1.0 2.3 8.9 12.4 15.3 15.8 9.2 8.6 9.9 10.7 10.7 10.9 MYO15A "DFNB3, MYO15" ENSG00000091536 "Myosin XVA" Q9UKN7 17 18108706-18179806 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 46.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.6;EFO-21: 2.8;HSkMC: 2.2;RPMI-8226: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "hippocampal formation: 2.7" HPA078501 Enhanced "HPA078501: " "unprognostic (2.48e-3)" "unprognostic (5.31e-2)" "unprognostic (2.87e-3)" "unprognostic (7.35e-3)" "unprognostic (4.92e-3)" "unprognostic (2.33e-1)" "unprognostic (8.32e-4)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-3)" "unprognostic (8.38e-2)" "unprognostic (4.18e-3)" "unprognostic (5.69e-3)" "unprognostic (9.89e-2)" "unprognostic (1.47e-1)" "unprognostic (2.21e-2)" 0.5 0.0 0.5 0.6 0.7 0.0 0.5 2.3 1.6 0.5 0.5 0.5 0.5 0.2 1.7 3.4 0.5 1.0 0.5 0.5 0.5 1.2 0.5 0.8 1.5 0.5 0.5 0.5 3.0 0.5 2.2 46.1 0.5 0.7 0.5 0.4 0.5 0.5 1.6 0.5 0.1 0.9 0.5 0.5 0.5 0.6 7.4 0.5 0.5 0.9 0.5 0.5 0.5 0.5 0.7 0.4 3.8 0.9 0.6 0.3 0.1 0.1 0.0 1.5 0.0 0.9 2.6 0.4 0.1 0.9 0.0 0.0 0.5 0.3 0.2 2.8 0.9 0.4 0.0 0.8 0.0 1.3 0.6 0.0 0.3 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.6 0.0 0.1 0.4 0.0 0.5 0.1 0.5 0.1 0.0 0.2 0.4 3.4 0.0 0.0 0.1 0.2 0.0 0.0 0.2 1.4 0.4 0.2 0.0 0.1 0.0 0.0 1.0 1.4 0.1 0.0 0.1 0.4 3.8 0.5 0.5 0.2 0.9 0.3 0.7 0.1 0.1 0.2 0.4 0.2 0.3 1.4 0.6 0.2 0.4 0.1 0.1 0.5 0.7 2.3 1.5 0.5 1.2 0.5 0.5 0.7 0.5 NEUROD4 "ATH-3, Atoh3, bHLHa4, MATH-3" ENSG00000123307 "Neuronal differentiation 4" Q9HD90 12 55019945-55030014 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 54.8" "Group enriched" "Detected in some" 6 "AF22: 3.6;SCLC-21H: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015545 Enhanced "HPA015545: " "unprognostic (1.78e-2)" 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 54.8 0.0 0.7 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.7 0.0 NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease mutation, Joubert syndrome, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved Uncertain Vesicles Vesicles "HPA046093: , HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" 3.1 4.3 8.5 1.8 13.7 0.8 5.1 2.1 7.2 5.6 4.7 4.9 8.8 1.7 7.2 11.3 2.1 19.3 4.3 4.4 9.0 7.5 8.7 1.5 5.7 1.5 3.8 6.2 5.4 3.5 17.7 28.1 2.1 20.3 4.4 2.6 4.6 2.8 8.9 36.7 1.7 1.8 7.2 5.4 1.9 3.7 25.0 7.2 0.0 8.9 3.2 1.3 4.1 3.7 3.5 1.0 1.0 0.3 3.2 1.8 0.7 8.6 2.7 5.7 4.2 3.3 6.9 1.2 2.2 7.2 7.8 7.7 2.8 6.5 0.5 5.8 5.1 4.2 2.7 7.0 9.3 1.6 3.5 0.2 1.7 1.9 4.6 1.3 0.0 4.7 4.2 12.1 3.9 4.9 0.1 0.8 4.6 1.7 0.8 2.1 2.6 4.5 0.0 6.0 0.2 13.2 0.7 3.1 3.1 3.2 3.9 7.9 4.7 1.0 3.1 4.5 3.9 5.0 7.0 2.4 2.5 0.6 13.3 0.2 3.2 0.7 0.1 0.1 1.2 0.3 1.8 2.7 0.9 0.6 1.0 3.5 1.8 1.4 1.0 3.2 0.1 0.1 0.1 0.7 8.5 13.7 2.1 7.2 9.0 7.5 3.8 6.2 20.3 7.2 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617297-98629868 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 24.0;brain: 45.6;pancreas: 19.5;pituitary gland: 71.6;testis: 20.7" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 16 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 16 "dendritic cells: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" 2488000 320000 "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: , HPA058320: " "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavourable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavourable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 4.3 24.0 7.1 2.3 8.4 1.0 1.4 0.2 45.6 8.2 3.8 3.2 0.1 1.1 1.8 3.9 2.2 1.5 1.6 3.2 9.2 11.0 0.9 0.9 0.8 0.7 9.4 2.2 1.5 19.5 0.8 71.6 0.8 7.0 2.1 1.4 1.3 1.5 2.2 2.9 4.0 1.3 2.9 2.9 6.1 1.9 20.7 5.0 0.0 1.6 0.1 0.9 1.4 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.4 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 125.7 0.0 0.9 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 10.8 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 7.1 8.4 0.2 24.6 9.2 11.0 9.4 2.2 7.0 5.0 NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 49.0;placenta: 17.7" "Cell line enhanced" "Detected in some" "NB-4: 16.7;PC-3: 9.3;RPMI-8226: 29.2;SCLC-21H: 50.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" HPA064874 Approved "Secreted to blood" "HPA064874: " "unprognostic (7.54e-2)" "unprognostic (4.45e-3)" "unprognostic (3.20e-1)" "unprognostic (4.31e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.20e-2)" "unprognostic (6.26e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-5)" "unprognostic (6.53e-3)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (3.43e-2)" 0.9 0.6 0.6 1.3 0.8 2.3 0.4 0.6 1.6 1.6 1.3 0.0 3.1 1.4 5.9 3.0 0.9 1.1 0.7 0.3 0.5 0.9 1.0 49.0 0.4 1.3 0.4 0.7 1.0 2.0 0.3 5.9 17.7 1.2 1.5 0.7 1.1 0.5 3.4 0.3 2.3 0.7 0.6 0.5 2.8 6.0 4.3 0.4 3.7 0.8 0.9 1.0 0.6 1.3 1.6 2.0 4.7 2.1 1.6 1.8 0.6 0.1 0.8 0.1 1.0 0.1 0.0 0.2 0.3 0.1 0.2 0.3 1.8 0.6 0.1 0.0 0.3 0.3 0.5 0.2 0.2 0.6 1.0 0.0 1.1 0.5 0.8 0.1 0.0 0.5 0.5 0.3 0.8 0.0 2.8 0.6 0.0 0.5 0.1 16.7 0.7 9.3 3.3 0.0 29.2 0.1 0.0 50.8 4.1 0.3 0.8 0.1 2.2 1.3 0.6 0.1 0.2 0.1 0.0 1.3 0.4 0.3 0.2 0.3 0.1 3.6 2.1 1.9 0.6 1.3 1.8 1.4 0.3 0.2 2.0 1.6 0.9 0.3 4.7 1.6 0.6 1.1 1.1 0.6 0.6 0.8 0.6 1.6 0.5 0.9 0.4 0.7 1.2 0.4 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831094-48835633 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.9;kidney: 72.9;pituitary gland: 127.7" "Cell line enhanced" "Detected in some" "HEK 293: 19.6;PC-3: 49.6;SCLC-21H: 19.7;SH-SY5Y: 18.2;SiHa: 17.2;U-266/84: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 3.0;memory CD4 T-cell: 6.5;memory CD8 T-cell: 6.3;naive CD4 T-cell: 2.7;naive CD8 T-cell: 8.2;T-reg: 2.1" "Lineage enriched" "Detected in single" 77 "T-cells: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" 5300000 Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favourable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 4.1 27.5 49.1 2.6 72.7 2.1 2.2 15.6 70.3 3.2 9.8 10.8 1.5 12.4 4.4 10.9 2.1 2.3 2.8 2.7 38.5 74.9 72.9 2.1 2.6 2.2 33.5 29.0 2.2 20.0 12.4 127.7 2.3 32.9 4.6 2.7 6.6 2.8 3.1 2.2 2.8 8.5 2.7 18.3 2.4 26.0 3.8 9.8 0.0 2.2 0.0 2.1 2.1 0.5 0.1 0.0 0.0 0.0 0.0 8.2 0.8 0.0 1.8 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 3.5 0.0 0.2 0.0 0.3 0.0 0.0 19.6 0.0 0.0 2.9 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 2.7 49.6 0.0 0.0 0.1 0.4 0.0 19.7 18.2 17.2 0.0 1.4 0.0 0.0 0.0 0.0 7.6 0.0 1.6 4.5 22.9 0.0 0.1 0.0 0.5 0.0 0.0 0.0 1.1 0.0 3.0 0.0 6.5 6.3 0.0 0.1 2.7 8.2 0.0 0.0 0.0 0.0 2.1 0.8 49.1 72.7 15.6 70.3 38.5 74.9 33.5 29.0 32.9 9.8 PEX5L "PEX5R, PXR2, TRIP8b" ENSG00000114757 "Peroxisomal biogenesis factor 5 like" Q8IYB4 3 179794958-180037053 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 41.9;parathyroid gland: 60.1" "Group enriched" "Detected in some" 4 "HDLM-2: 5.6;MOLT-4: 19.8;RPMI-8226: 15.8;SCLC-21H: 9.7;U-266/70: 12.7" "Cancer enhanced" "Detected in some" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058026 Enhanced "HPA058026: " "unprognostic (5.21e-2)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.93e-1)" "unprognostic (1.82e-3)" "unprognostic (2.68e-2)" "unprognostic (1.52e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-4)" "unprognostic (9.67e-5)" "unprognostic (3.84e-1)" "unprognostic (2.66e-10)" "unprognostic (2.27e-3)" "unprognostic (1.45e-2)" "unprognostic (1.69e-2)" "unprognostic (4.03e-3)" 1.3 1.4 17.0 1.3 26.6 1.2 1.2 1.8 41.9 1.3 1.2 24.5 0.0 1.3 1.2 1.5 1.3 1.4 1.2 1.3 16.9 8.1 1.3 1.2 1.3 1.2 38.4 18.9 2.9 10.6 60.1 5.3 1.1 24.1 1.4 1.2 0.0 1.3 1.2 1.4 1.2 1.3 1.1 32.3 1.2 1.3 5.4 36.5 0.0 1.3 0.0 1.2 1.2 0.4 0.8 0.4 0.8 0.1 0.4 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 5.6 0.0 0.0 0.1 0.0 0.0 1.1 0.1 0.1 0.0 0.0 1.0 0.0 0.0 2.9 0.0 0.0 19.8 0.0 1.2 0.2 0.1 0.0 15.8 0.0 0.0 9.7 0.5 0.0 0.0 0.0 0.0 1.5 0.0 2.0 0.1 0.0 0.5 12.7 0.4 0.0 0.3 0.1 0.5 0.6 0.1 0.2 0.6 0.1 0.5 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.8 0.4 0.1 0.4 0.0 0.0 17.0 26.6 1.8 26.0 16.9 8.1 38.4 18.9 24.1 36.5 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "pituitary gland: 811.1" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HMC-1: 4.1;THP-1: 5.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Region enriched" "Detected in single" 5 "hypothalamus: 1.8" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hypothalamus: 77.9" "CAB002762, HPA046135, HPA063644" Enhanced "Secreted to blood" "CAB002762: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favourable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" 1.0 3.2 0.3 0.8 0.3 0.5 0.3 0.3 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 0.3 0.0 0.3 0.3 0.3 1.8 0.5 0.3 0.3 0.6 0.3 0.3 0.3 22.2 0.0 811.1 0.9 0.3 0.3 0.0 0.3 0.4 0.3 3.6 0.9 0.3 0.3 0.3 1.3 0.4 2.9 0.3 0.3 0.3 0.4 0.3 0.3 0.3 13.7 22.2 6.6 10.1 12.6 10.5 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 4.1 1.1 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 9.9 6.6 9.8 10.1 7.7 12.8 7.5 9.3 12.5 13.7 9.9 10.5 3.1 12.6 5.9 22.2 7.9 7.6 0.3 0.3 0.3 0.3 0.3 1.8 0.3 0.3 0.3 0.3 POU1F1 "GHF-1, PIT1, POU1F1a" ENSG00000064835 "POU class 1 homeobox 1" P28069 3 87259404-87276587 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "pituitary gland: 138.8" "Cell line enhanced" "Detected in some" "A549: 1.8;SiHa: 1.1;U-87 MG: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041646, HPA050624" Enhanced "HPA041646: AB_10794672, HPA050624: AB_2681192" "unprognostic (1.88e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.60e-1)" "unprognostic (2.93e-1)" "unprognostic (1.87e-2)" "unprognostic (7.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.50e-1)" "unprognostic (4.69e-3)" "unprognostic (1.55e-1)" "unprognostic (1.52e-2)" "unprognostic (1.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.05e-4)" 0.3 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 138.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.8 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRL ENSG00000172179 Prolactin P01236 6 22287244-22297501 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "pituitary gland: 1739.5" "Cell line enhanced" "Detected in some" "Daudi: 17.6;SCLC-21H: 6.6;U-937: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 1.2;non-classical monocyte: 1.0" "Group enriched" "Detected in many" 12 "monocytes: 1.0;T-cells: 1.2" "Not detected" "Not detected" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" 75460000 3300000 "CAB023353: AB_617369, HPA042416: AB_2677987, HPA062017: AB_2684660" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (5.89e-3)" "unprognostic (4.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.11e-4)" "unprognostic (4.54e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-2)" "unprognostic (4.29e-5)" "unprognostic (2.20e-1)" 0.2 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1739.5 21.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 PRLHR "GPR10, PrRPR" ENSG00000119973 "Prolactin releasing hormone receptor" P49683 10 118589989-118595699 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 11.3;brain: 10.6;cervix, uterine: 8.3;pituitary gland: 11.8;smooth muscle: 8.1" "Cell line enriched" "Detected in single" 9 "SH-SY5Y: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA039361 Enhanced "HPA039361: AB_10673527" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" 0.2 11.3 1.4 0.2 3.0 0.2 0.1 3.2 5.1 8.3 0.2 0.8 0.0 0.3 5.4 0.2 0.2 0.4 0.2 0.1 0.6 4.0 0.1 0.2 0.2 0.1 3.4 0.9 0.1 0.5 0.1 11.8 0.1 10.6 0.3 0.2 0.1 0.2 1.4 0.2 0.2 0.2 8.1 0.5 0.2 0.5 0.2 1.0 0.0 0.2 0.0 0.1 0.1 5.4 0.5 0.4 1.3 0.3 0.7 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.5 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.2 1.3 0.7 0.3 0.4 0.0 0.0 1.4 3.0 3.2 1.9 0.6 4.0 3.4 0.9 10.6 1.0 PROP1 ENSG00000175325 "PROP paired-like homeobox 1" O75360 5 177992235-177996242 "Disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "pituitary gland: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049839 Enhanced "HPA049839: " "unprognostic (2.90e-1)" "unprognostic (4.90e-1)" "unprognostic (2.13e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343865 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 160.7" "Cell line enriched" "Detected in some" 12 "AF22: 186.3" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" 166965 1800000 "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favourable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 7.8 6.6 55.5 2.0 43.3 0.9 27.7 38.6 58.5 30.7 7.2 26.9 9.9 2.5 25.2 18.7 25.0 7.2 18.2 29.4 42.3 29.7 12.7 3.4 6.5 2.6 31.6 27.0 7.2 3.4 160.7 52.5 11.8 31.4 38.5 7.7 19.0 12.0 18.1 1.5 3.6 4.0 17.7 23.4 12.4 5.4 16.8 23.3 1.3 5.1 8.7 5.3 7.7 18.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 186.3 2.2 0.0 0.1 15.2 4.8 14.3 2.7 3.7 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 14.4 0.1 0.0 0.3 0.0 0.0 0.0 0.8 12.7 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.6 0.1 10.3 0.0 0.0 0.0 13.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 43.3 38.6 42.0 42.3 29.7 31.6 27.0 31.4 23.3 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase, receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.6;pancreas: 28.9;pituitary gland: 43.4" "Group enriched" "Detected in some" 8 "U-2 OS: 19.8;U-87 MG: 73.7" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA007152: , HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavourable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 1.7 22.3 19.3 4.7 35.7 1.7 1.3 17.3 89.6 1.2 2.4 2.5 0.0 2.5 1.5 1.2 1.5 1.3 1.5 1.4 21.6 40.1 1.5 1.2 1.4 1.3 14.4 19.8 1.3 28.9 1.2 43.4 1.4 22.0 1.4 1.9 3.1 1.2 1.3 1.2 2.0 2.5 2.4 3.5 1.3 6.0 1.4 2.1 0.0 1.5 0.0 1.2 2.7 0.0 0.1 0.3 0.2 0.0 0.0 0.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 2.5 0.0 6.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 4.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.2 73.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.6 3.7 19.3 35.7 17.3 54.0 21.6 40.1 14.4 19.8 22.0 2.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;HDLM-2: 21.5;NB-4: 22.1;SCLC-21H: 12.2;SH-SY5Y: 12.4;THP-1: 10.8;U-87 MG: 15.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavourable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.3 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 0.0 0.4 0.0 0.0 21.5 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.3 22.1 3.0 0.7 0.0 0.7 0.1 0.0 0.0 12.2 12.4 0.0 0.0 0.0 0.0 10.8 3.2 5.0 1.9 0.0 0.3 0.1 0.0 0.0 15.1 9.0 3.6 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37344574-37373322 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.6;blood: 137.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.5;SCLC-21H: 23.8;SK-MEL-30: 80.0;U-266/84: 62.5" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "neutrophil: 137.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 3.2 77.6 4.3 5.4 5.8 17.0 6.4 1.2 11.6 9.2 11.3 2.2 1.5 2.2 6.2 43.7 2.4 1.9 5.5 2.9 6.7 17.9 12.4 1.3 6.1 7.4 3.9 5.0 1.4 5.5 9.6 31.6 7.8 5.9 3.5 4.2 21.2 14.7 2.8 4.0 14.2 2.3 3.4 3.0 8.5 3.4 2.6 0.5 2.3 1.8 4.4 4.8 7.0 2.9 0.2 10.7 137.6 29.7 0.0 0.0 12.1 0.1 7.9 0.0 0.0 1.0 2.6 0.0 1.0 17.5 1.3 2.1 0.5 1.4 0.0 0.6 5.9 0.0 0.5 0.0 2.1 0.1 15.3 3.5 0.0 1.5 0.1 0.5 0.0 1.5 0.0 9.7 0.0 5.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.0 0.0 0.1 8.6 2.1 23.8 0.0 1.3 0.0 80.0 0.1 0.5 3.7 0.0 0.0 0.0 0.1 3.0 62.5 0.0 5.3 0.0 0.0 0.6 29.7 0.2 0.0 3.4 0.0 0.2 0.0 0.0 10.7 0.1 0.0 0.0 137.6 0.0 0.3 0.2 0.0 12.1 4.3 5.8 1.2 11.6 6.7 17.9 3.9 5.0 5.9 0.5 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602503 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 133.0;brain: 94.1;pituitary gland: 76.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 26.2;HSkMC: 22.4;SCLC-21H: 22.8;SH-SY5Y: 9.9;WM-115: 16.7" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" 54000 "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favourable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavourable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 3.5 133.0 13.3 11.0 94.1 0.9 0.9 5.6 55.9 1.4 5.4 5.8 0.0 17.3 2.1 0.9 1.0 0.8 2.2 1.4 10.5 79.4 1.0 0.8 1.9 0.9 21.7 11.0 1.3 10.7 1.1 76.5 1.1 57.7 2.1 5.5 1.5 0.9 1.3 0.8 1.0 8.0 5.2 10.3 0.8 8.0 0.9 5.0 0.0 3.1 0.0 0.8 1.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 4.9 4.1 1.1 26.2 0.1 0.2 0.9 1.9 4.9 0.2 0.4 0.0 0.4 0.3 0.1 0.1 0.0 2.5 0.0 0.2 0.0 0.3 0.0 0.3 0.3 2.2 22.4 0.1 2.7 0.9 0.0 0.1 0.2 2.4 0.1 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.3 0.0 22.8 9.9 0.0 0.2 1.1 0.0 0.0 0.0 2.6 1.0 0.1 1.7 0.0 0.0 0.1 0.7 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 13.3 94.1 5.6 23.0 10.5 79.4 21.7 11.0 57.7 5.0 SCG5 "7B2, SGNE1, SgV" ENSG00000166922 "Secretogranin V" P05408 15 32641676-32697098 "Predicted secreted proteins" Transport "Chaperone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.1;pancreas: 63.5;parathyroid gland: 60.1;pituitary gland: 74.6" "Cell line enhanced" "Detected in some" "HHSteC: 14.7;HSkMC: 18.2;NTERA-2: 8.2;SCLC-21H: 16.8;SH-SY5Y: 19.5;U-87 MG: 25.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 82.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 2.8;naive CD4 T-cell: 1.0" "Lineage enriched" "Detected in single" 28 "T-cells: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013136, HPA074618" Enhanced "Secreted to blood" 22000 "HPA013136: AB_1856657, HPA074618: AB_2732262" "unprognostic (1.71e-1)" "unprognostic (9.87e-2)" "unprognostic (7.94e-2)" "unprognostic (1.30e-2)" "unprognostic (3.59e-3)" "prognostic unfavourable (9.64e-4)" "unprognostic (2.69e-1)" "unprognostic (1.27e-3)" "unprognostic (4.69e-2)" "unprognostic (1.97e-1)" "unprognostic (5.62e-3)" "unprognostic (3.92e-1)" "prognostic unfavourable (4.51e-9)" "unprognostic (3.57e-2)" "unprognostic (8.13e-2)" "unprognostic (3.08e-3)" "unprognostic (8.88e-2)" 1.2 30.7 24.0 2.2 47.2 0.9 2.5 36.4 71.1 1.0 4.4 13.0 0.0 9.0 3.4 21.8 1.0 2.4 3.4 1.0 30.5 36.9 1.2 2.2 2.5 1.3 25.2 23.1 2.0 63.5 60.1 74.6 0.9 30.5 3.2 5.5 15.4 0.7 1.2 0.7 1.3 3.3 3.9 24.1 1.0 21.0 3.0 9.5 0.0 1.8 0.0 0.9 2.5 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.2 0.1 0.0 0.1 0.3 2.5 0.0 2.2 0.2 0.2 0.2 0.0 0.0 0.2 1.0 0.2 0.6 0.3 0.1 0.6 0.3 0.1 0.3 0.0 0.0 14.7 0.1 0.4 18.2 0.1 0.4 0.2 0.3 0.1 0.3 0.4 0.0 0.1 0.1 8.2 0.4 0.0 0.2 0.3 0.2 0.0 16.8 19.5 0.1 0.0 0.1 0.0 0.2 0.0 2.8 1.9 0.1 0.2 0.3 1.1 0.2 25.5 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 24.0 47.2 36.4 50.8 30.5 36.9 25.2 23.1 30.5 9.5 SIX6 "OPTX2, Six9" ENSG00000184302 "SIX homeobox 6" O95475 14 60508951-60512850 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cataract, Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pituitary gland: 43.3" "Cell line enriched" "Detected in some" 16 "MOLT-4: 29.4" "Cancer enriched" "Detected in single" 8 "glioma: 1.0" "Region enriched" "Detected in single" 8 "hypothalamus: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001403 Approved Approved Nucleoplasm Nucleoplasm "HPA001403: AB_1079993" "unprognostic (2.76e-1)" "unprognostic (6.14e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-2)" 0.1 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.4 0.0 10.6 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 TBX19 "dj747L4.1, TPIT" ENSG00000143178 "T-box 19" O60806 1 168281040-168314426 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "pituitary gland: 50.4" "Cell line enhanced" "Detected in many" "HaCaT: 9.5;HDLM-2: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005800, HPA072686" Enhanced Approved "Nuclear speckles" "Nuclear speckles" "HPA005800: AB_1080219, HPA072686: " "unprognostic (2.47e-1)" "unprognostic (1.20e-2)" "unprognostic (8.76e-4)" "unprognostic (1.43e-2)" "unprognostic (3.09e-2)" "unprognostic (8.36e-2)" "unprognostic (7.14e-7)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (5.58e-2)" "unprognostic (9.78e-3)" "unprognostic (1.28e-1)" "prognostic unfavourable (4.55e-9)" "unprognostic (8.57e-2)" "unprognostic (6.63e-2)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" 1.0 0.4 1.0 1.0 1.0 0.5 2.5 1.0 1.0 1.5 1.3 1.0 1.0 0.8 5.3 1.0 1.1 2.0 1.4 1.0 1.0 0.8 1.0 1.0 2.2 2.1 1.0 1.0 2.9 1.0 0.2 50.4 1.0 1.0 1.2 1.1 1.0 2.2 1.4 1.0 1.9 1.0 3.6 1.0 2.1 0.6 1.0 1.0 1.0 1.0 1.0 1.3 1.3 1.2 1.6 6.3 2.7 2.4 2.6 3.1 1.3 1.6 0.1 1.4 5.3 2.5 1.2 1.7 2.9 1.5 1.0 1.6 2.4 1.7 1.5 2.9 1.1 9.5 0.8 0.7 1.4 8.1 1.4 0.3 1.7 0.7 2.9 2.6 3.6 2.2 2.6 0.3 1.5 1.2 1.8 2.4 1.3 0.3 1.4 2.4 0.4 1.0 2.2 0.7 0.5 2.3 0.7 1.9 2.8 1.6 1.2 1.6 0.4 2.2 2.1 1.0 2.4 2.0 2.9 1.6 1.3 1.2 0.2 0.8 2.8 0.5 1.8 0.8 3.1 1.3 1.4 1.2 2.2 2.0 1.8 1.6 1.5 1.3 2.7 2.6 2.4 6.3 2.0 1.3 1.0 1.0 1.0 1.0 1.0 0.8 1.0 1.0 1.0 1.0 TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7916145-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 56.6" "Cell line enhanced" "Detected in some" "PC-3: 5.6;REH: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA074356 Enhanced Approved Vesicles Vesicles "HPA074356: " "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" 0.3 2.0 1.6 0.2 2.8 0.6 0.3 1.9 6.4 5.0 0.6 0.0 0.3 6.0 2.8 0.5 0.3 0.7 0.2 2.1 0.7 0.8 3.7 4.0 0.3 0.1 0.5 1.7 0.3 0.3 0.9 56.6 0.4 1.9 2.5 0.1 0.6 0.8 0.7 0.3 0.5 5.7 2.0 0.6 0.3 0.4 0.5 0.0 0.0 0.3 0.0 0.1 1.1 0.8 0.1 0.3 0.0 0.1 0.0 2.9 0.1 0.1 0.2 0.1 0.5 0.1 0.0 3.3 2.6 0.0 0.2 0.0 0.5 0.0 0.1 3.0 0.1 1.9 0.0 0.0 0.0 3.4 1.1 0.5 0.2 0.6 0.2 1.7 0.3 0.2 0.1 0.0 0.0 0.0 0.7 0.5 0.0 1.5 1.2 0.2 0.6 5.6 13.6 0.0 3.0 0.2 0.0 1.0 2.5 0.3 0.0 0.6 0.9 0.5 0.2 1.8 2.9 2.0 0.9 0.8 0.9 0.8 0.4 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.6 0.1 0.9 1.9 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.3 0.0 0.1 1.6 2.8 1.9 6.4 0.7 0.8 0.5 1.7 1.9 0.0 TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086621-109119584 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.0;pituitary gland: 3.3;thyroid gland: 1.6" "Cell line enhanced" "Detected in some" "PC-3: 1.6;SH-SY5Y: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055162 Approved "HPA055162: " "unprognostic (1.92e-2)" "unprognostic (8.58e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.3 0.5 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSHB ENSG00000134200 "Thyroid stimulating hormone beta" P01222 1 115029824-115034309 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 77 "pituitary gland: 192.4" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;SH-SY5Y: 1.0;U-937: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022202, HPA042681" Enhanced "Secreted to blood" "CAB022202: , HPA042681: " "unprognostic (2.14e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" 0.1 0.0 0.1 0.9 0.1 2.4 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 1.4 0.1 1.4 0.0 1.8 0.1 0.1 0.0 0.3 0.1 1.4 0.1 0.1 0.1 0.1 1.6 0.0 192.4 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.1 0.1 0.1 0.4 1.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.2 0.1 2.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165593 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 59.4;pituitary gland: 30.4" "Cell line enhanced" "Detected in some" "SH-SY5Y: 35.9;SK-MEL-30: 96.8;U-2 OS: 17.6;WM-115: 29.0" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" 1273770 2800000 "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavourable (4.25e-4)" "prognostic unfavourable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 3.8 3.1 10.9 2.3 25.2 1.3 1.1 1.3 59.4 1.1 1.5 1.3 0.0 1.3 2.2 1.1 1.1 1.1 1.2 1.2 12.2 51.0 1.4 1.1 1.1 1.1 3.9 22.8 1.1 6.2 1.1 30.4 1.2 41.2 1.2 1.2 0.5 1.1 1.1 1.1 1.4 1.3 1.5 6.6 1.2 3.6 1.4 0.5 0.0 1.2 0.0 1.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.2 1.9 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.7 0.4 0.0 4.6 0.0 0.4 3.6 0.4 0.1 0.0 0.0 0.0 0.0 2.9 35.9 0.0 0.1 96.8 0.0 0.0 0.0 0.0 17.6 0.0 0.4 0.0 0.1 0.9 2.8 0.0 29.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 25.2 1.3 59.4 12.2 51.0 3.9 22.8 41.2 0.5 WDR19 "DYF-2, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182404-39285810 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease mutation, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 41.1" "Cell line enhanced" "Detected in many" "ASC diff: 25.2;ASC TERT1: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039616, HPA058847" Approved Approved Nucleoplasm Nucleoplasm "HPA039616: AB_10796331, HPA058847: " "unprognostic (1.80e-1)" "unprognostic (9.32e-2)" "unprognostic (6.40e-2)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (1.26e-3)" "prognostic unfavourable (4.43e-4)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "prognostic favourable (2.70e-4)" "prognostic unfavourable (8.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (5.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.56e-2)" 8.5 7.6 8.1 4.8 12.9 3.4 9.2 21.0 14.5 13.2 7.8 5.7 7.8 1.9 15.5 11.2 5.4 20.9 8.6 5.1 11.7 4.1 8.6 7.0 8.6 4.4 6.0 11.0 19.0 6.6 10.1 41.1 6.3 14.6 8.1 4.3 6.9 7.6 8.2 3.1 6.0 5.7 9.5 9.7 4.3 8.0 12.7 7.3 6.8 17.1 3.8 5.0 9.9 8.9 3.9 1.1 1.5 2.0 2.3 2.4 0.8 3.2 2.3 5.5 6.5 25.2 28.3 2.5 4.2 9.7 4.5 5.9 1.4 3.6 5.2 2.1 4.1 1.9 5.4 2.8 5.0 0.3 3.9 1.0 4.3 2.6 7.9 5.1 1.3 17.2 6.1 6.0 3.8 5.4 4.6 5.3 5.4 1.1 3.5 3.6 1.8 2.6 4.3 5.6 2.3 3.6 1.3 6.0 5.6 4.2 1.3 2.8 2.8 1.9 3.9 4.4 2.9 9.6 4.2 3.9 3.5 3.7 6.5 1.5 1.9 0.7 1.2 0.9 1.7 2.0 1.3 3.4 2.1 2.4 1.1 3.9 2.1 2.1 1.5 2.3 1.7 0.7 1.4 0.8 8.1 12.9 21.0 14.5 11.7 4.1 6.0 11.0 14.6 7.3 ZBTB8B "DKFZp547H154, RP1-27O5.1, ZNF916B" ENSG00000273274 "Zinc finger and BTB domain containing 8B" Q8NAP8 1 32465069-32496686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 10.8" "Cell line enhanced" "Detected in some" "RT4: 3.7;SCLC-21H: 3.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA055553 Enhanced "HPA055553: " "unprognostic (8.32e-4)" "unprognostic (1.23e-1)" "unprognostic (3.83e-1)" "unprognostic (3.83e-5)" "unprognostic (1.86e-2)" "unprognostic (5.65e-2)" "unprognostic (1.67e-4)" "unprognostic (1.57e-2)" "unprognostic (5.94e-2)" "unprognostic (3.43e-3)" "unprognostic (9.08e-3)" "unprognostic (1.35e-1)" "unprognostic (2.93e-2)" "unprognostic (3.44e-2)" "unprognostic (6.11e-2)" "unprognostic (3.26e-3)" "unprognostic (5.88e-3)" 0.4 1.3 5.1 0.6 2.8 2.5 0.6 2.2 5.0 0.4 0.3 1.3 0.7 0.5 1.2 1.3 0.7 0.7 0.6 0.4 3.3 4.7 0.6 0.6 0.5 0.9 2.6 2.7 1.0 0.8 1.0 10.8 0.7 4.1 0.8 0.4 0.2 1.7 0.5 3.4 1.7 0.5 0.5 1.6 0.8 0.5 3.1 1.6 0.0 0.8 0.0 0.6 1.0 0.4 1.4 1.2 3.2 0.8 1.3 0.7 0.2 0.2 0.1 2.0 1.5 0.2 0.5 0.6 0.2 0.1 0.7 0.6 0.2 0.5 0.4 0.7 0.1 0.7 2.3 0.2 0.5 0.7 2.5 0.3 0.7 0.4 0.0 0.3 0.4 0.2 0.2 0.5 0.0 0.2 0.2 0.9 0.1 0.3 0.3 0.6 2.1 0.9 0.3 0.2 0.3 0.4 3.7 3.6 2.2 1.3 0.5 0.2 0.4 0.3 0.9 0.5 0.4 0.6 0.3 0.7 0.7 0.4 0.5 0.4 0.4 3.2 0.8 1.0 0.6 0.5 0.6 0.8 0.6 0.5 0.3 1.4 0.7 0.7 2.9 1.3 0.7 1.2 0.5 0.2 5.1 2.8 2.2 5.0 3.3 4.7 2.6 2.7 4.1 1.6