Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 18.3;SK-BR-3: 9.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 6.1" "Group enriched" "Detected in many" 5 "NK-cells: 1.5;T-cells: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favourable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 2.5 1.8 3.5 2.5 5.6 0.8 2.6 2.8 4.4 3.5 1.8 0.9 5.5 0.8 10.7 5.4 5.1 2.2 4.8 2.4 3.2 3.7 6.1 1.1 4.1 0.6 3.3 1.7 5.3 2.7 4.8 1.3 4.5 3.0 3.3 1.2 2.3 2.0 4.0 3.0 1.8 0.9 2.7 6.9 0.8 1.1 8.0 0.7 0.6 5.3 2.3 1.5 5.1 1.1 0.0 0.0 0.7 0.0 1.5 6.1 0.5 0.7 7.5 2.4 0.3 0.6 2.5 0.4 1.9 8.7 1.2 1.2 3.3 6.4 0.0 1.5 1.0 1.1 2.6 1.5 1.0 1.6 2.0 0.5 1.1 1.0 1.4 0.4 0.8 3.0 4.6 0.7 2.1 5.2 0.2 0.4 3.9 1.4 0.0 1.0 5.7 2.1 0.0 1.7 0.4 18.3 1.3 2.5 0.3 2.2 9.9 3.8 4.8 1.6 5.9 0.3 0.6 0.6 1.8 0.0 0.1 0.0 1.3 0.0 1.5 0.1 0.0 0.0 6.1 0.0 0.2 0.0 1.7 1.0 0.0 0.0 0.1 0.5 0.7 1.5 0.0 0.0 0.0 0.5 3.5 5.6 2.8 4.4 3.2 3.7 3.3 1.7 3.0 0.7 BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133399995-133475222 "Disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "blood: 12.7" "Group enriched" "Detected in some" 7 "Daudi: 5.5;U-698: 6.5" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.7" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "T-reg: 12.7" "Lineage enriched" "Detected in single" 48 "T-cells: 12.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA038464: AB_10672746, HPA062959: AB_2684912" "unprognostic (1.58e-3)" "unprognostic (7.47e-4)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (9.59e-2)" "unprognostic (4.04e-5)" "unprognostic (8.13e-2)" "unprognostic (5.57e-2)" "unprognostic (6.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.74e-2)" "unprognostic (4.70e-2)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.23e-2)" "unprognostic (2.21e-2)" 0.0 0.0 0.1 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.1 0.2 0.0 0.0 12.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.8 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 1.7 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248490-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm Nucleoplasm "HPA031355: AB_10611812" "prognostic favourable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (2.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.23e-2)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-1)" "prognostic favourable (2.25e-4)" "unprognostic (8.48e-3)" "prognostic favourable (6.51e-5)" "unprognostic (6.55e-2)" "unprognostic (3.22e-1)" "unprognostic (6.86e-2)" "unprognostic (9.85e-2)" 25.9 9.4 19.9 9.4 17.7 11.8 53.4 18.1 27.0 13.6 14.6 5.4 15.2 14.1 9.9 14.7 17.4 11.4 13.6 19.8 17.9 12.9 9.7 12.3 17.7 11.3 11.3 15.9 13.1 5.6 7.7 12.4 7.7 9.5 13.1 11.7 11.6 20.5 12.6 73.0 19.4 14.3 14.4 6.1 9.3 13.7 24.7 6.2 8.2 9.3 31.3 10.6 11.5 22.3 2.4 2.7 4.6 1.6 0.6 8.1 1.1 17.5 14.1 7.7 20.5 24.9 17.3 0.0 16.3 14.8 25.3 17.3 11.0 16.2 5.6 10.0 23.7 23.7 14.8 15.7 12.6 14.3 12.0 4.1 20.5 0.0 17.0 12.3 7.9 18.0 21.7 11.6 9.5 20.1 0.0 0.1 13.4 25.0 12.9 5.0 3.3 24.4 14.0 0.0 5.2 9.6 19.5 12.7 5.4 15.3 12.4 12.0 25.3 15.9 13.5 20.4 0.5 29.8 20.1 3.7 4.9 2.7 21.0 5.7 15.8 0.6 1.1 4.6 4.1 1.6 4.0 2.4 4.3 4.2 1.1 1.3 3.3 2.3 0.7 0.6 1.2 2.7 8.1 1.1 19.9 17.7 18.1 27.0 17.9 12.9 11.3 15.9 9.5 6.2 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300487-40317813 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease mutation, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;pituitary gland: 32.1;retina: 40.8" "Cell line enhanced" "Detected in some" "HDLM-2: 34.6;HMC-1: 33.4;THP-1: 37.4" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 6.4;myeloid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 6.4" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" Vesicles Nucleoplasm "HPA056316: , HPA075286: " "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavourable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 0.7 2.3 17.2 2.6 19.5 7.6 3.1 2.3 12.1 10.0 3.6 32.0 17.4 4.6 3.9 1.5 0.7 3.7 6.5 1.0 20.8 14.5 4.3 0.6 2.8 4.2 29.8 10.5 0.6 1.7 28.3 32.1 0.9 16.3 8.8 2.6 40.8 13.7 21.3 0.3 2.0 3.3 1.3 35.3 3.2 12.8 0.8 19.7 0.2 4.3 0.9 2.5 4.0 0.5 0.7 2.7 6.4 0.7 0.4 0.3 0.1 4.2 0.1 0.6 0.3 0.9 0.5 2.9 0.0 0.0 0.2 0.5 0.1 2.4 1.2 3.7 0.1 0.7 0.0 0.0 0.1 34.6 0.5 0.7 0.3 9.7 0.6 0.3 33.4 1.8 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.9 0.4 0.7 0.8 0.4 0.8 0.0 2.4 0.0 5.1 0.5 0.8 0.0 4.3 0.4 5.4 37.4 0.0 0.0 4.4 0.0 0.1 0.5 0.0 1.1 0.3 4.4 0.2 0.0 0.2 6.4 0.0 0.5 0.0 0.5 0.2 0.0 2.7 0.7 0.1 0.0 1.1 0.4 0.7 0.3 0.3 0.1 17.2 19.5 2.3 10.8 20.8 14.5 29.8 10.5 16.3 19.7 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.4;retina: 37.2;salivary gland: 38.9;thyroid gland: 18.1" "Group enriched" "Detected in some" 6 "BEWO: 52.5;Hep G2: 20.7;SK-MEL-30: 17.2;WM-115: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: " "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 2.2 2.0 11.2 2.3 16.3 1.2 1.5 1.5 8.9 1.7 3.4 26.4 1.6 2.3 1.8 1.5 1.6 1.2 1.4 2.1 14.9 9.8 1.4 1.3 1.3 1.4 18.4 8.1 1.6 5.4 1.1 5.3 1.9 12.4 1.7 1.3 37.2 38.9 3.4 1.5 1.8 2.5 1.4 25.0 1.2 1.8 6.4 15.2 0.0 18.1 1.4 1.2 1.3 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.3 52.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.4 20.7 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 2.3 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 17.2 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 16.3 1.5 8.0 14.9 9.8 18.4 8.1 12.4 15.2 CRYAA "CRYA1, HSPB4" ENSG00000160202 "Crystallin alpha A" P02489 21 43169008-43172805 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Chaperone, Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "kidney: 45.5" "Cell line enriched" "Detected in single" 140 "Hep G2: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037737, HPA038430" Supported Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA037737: , HPA038430: " "unprognostic (3.68e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 CRYAA2 ENSG00000276076 "Crystallin alpha A2" 21 6560714-6564489 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "kidney: 34.4" "Cell line enriched" "Detected in single" 200 "Hep G2: 28.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037737, HPA038430" Approved Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA037737: , HPA038430: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.0 0.0 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908565-111923722 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease mutation, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 743.1;skeletal muscle: 581.1" "Group enriched" "Detected in some" 5 "ASC diff: 230.1;fHDF/TERT166: 75.0" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" 12000 "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: " "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavourable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavourable (1.70e-5)" 107.4 11.5 47.8 16.7 82.3 2.1 69.5 24.8 153.7 22.4 23.6 132.9 7.2 5.5 14.8 25.9 41.9 13.5 14.0 743.1 65.9 44.0 151.8 3.8 8.4 3.9 139.2 29.7 8.8 6.6 3.3 8.6 16.1 80.7 30.3 12.9 23.3 30.6 75.1 581.1 18.1 6.2 45.2 168.0 5.5 11.6 3.9 101.8 0.0 40.7 94.1 9.2 16.2 53.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.3 230.1 10.1 1.6 6.4 0.2 0.1 0.2 0.1 0.0 0.0 3.8 75.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 1.2 0.6 1.9 0.0 0.0 8.1 1.0 0.0 0.5 0.0 0.5 0.2 18.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.4 0.8 3.4 0.5 0.0 0.1 29.8 10.7 0.8 0.3 0.1 0.0 0.0 0.6 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 82.3 24.8 48.5 65.9 44.0 139.2 29.7 80.7 101.8 CRYBA1 CRYB1 ENSG00000108255 "Crystallin beta A1" P05813 17 29246863-29254494 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 1.4;bone marrow: 1.4;brain: 2.8;lymphoid tissue: 1.5" "Group enriched" "Detected in some" 8 "AF22: 6.7;BEWO: 8.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.8" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA022016 Supported "HPA022016: " "unprognostic (2.89e-2)" "unprognostic (1.57e-1)" "unprognostic (8.75e-2)" "unprognostic (1.37e-1)" "unprognostic (9.62e-2)" "unprognostic (4.27e-3)" "unprognostic (2.08e-1)" "unprognostic (5.60e-2)" "unprognostic (2.52e-2)" "unprognostic (9.90e-2)" "unprognostic (5.85e-3)" "unprognostic (2.83e-1)" "unprognostic (2.09e-6)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.31e-2)" "unprognostic (6.84e-3)" 0.0 0.0 0.2 1.5 0.3 1.4 0.0 0.0 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.4 0.6 0.0 0.0 0.0 1.3 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.4 1.4 0.0 0.7 0.1 0.0 0.0 6.7 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.3 1.4 0.4 0.4 0.7 0.1 0.8 1.0 0.3 0.1 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.3 0.0 2.8 0.2 0.2 0.5 0.0 0.0 0.0 CRYBA2 ENSG00000163499 "Crystallin beta A2" P53672 2 218990189-218993421 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.6;intestine: 5.8;pancreas: 16.2;pituitary gland: 12.2;stomach 1: 6.1" "Cell line enriched" "Detected in some" 7 "BEWO: 39.9" "Cancer enriched" "Detected in some" 15 "pancreatic cancer: 16.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062293 Supported "HPA062293: " "unprognostic (5.29e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (4.19e-1)" "unprognostic (6.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-1)" "unprognostic (1.66e-2)" "unprognostic (3.75e-1)" "prognostic favourable (7.62e-4)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.19e-1)" 0.3 4.6 0.3 0.3 2.0 0.0 0.3 0.3 0.8 0.3 5.8 0.3 0.3 3.5 0.3 0.3 0.3 0.0 0.3 0.3 0.6 0.5 0.3 0.3 0.3 0.3 0.6 0.3 0.3 16.2 0.1 12.2 0.3 0.7 0.5 2.8 0.8 0.3 0.3 0.3 0.1 4.7 0.3 0.3 0.3 6.1 1.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 5.8 1.4 1.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.3 0.8 0.6 0.5 0.6 0.3 0.7 0.3 CRYBA4 ENSG00000196431 "Crystallin beta A4" P53673 22 26621964-26630672 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 2.2;epididymis: 6.0;retina: 2.0;testis: 4.1" "Cell line enriched" "Detected in some" 4 "HEL: 12.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Not detected" "Not detected" HPA071178 Supported "HPA071178: " "unprognostic (6.69e-2)" "unprognostic (3.94e-3)" "unprognostic (5.61e-5)" "unprognostic (1.74e-2)" "unprognostic (5.57e-2)" "unprognostic (2.32e-2)" "unprognostic (2.71e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-6)" "unprognostic (2.86e-1)" "unprognostic (1.20e-6)" "unprognostic (1.87e-2)" "unprognostic (7.23e-2)" "unprognostic (7.71e-2)" "unprognostic (3.70e-1)" 0.1 0.0 0.5 0.3 0.5 0.4 0.1 0.1 0.5 0.2 0.5 0.1 0.1 0.8 0.1 6.0 0.1 0.0 0.1 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 2.0 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.8 0.1 4.1 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.5 0.2 0.4 0.3 0.1 0.1 0.1 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618088 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 10.6;epididymis: 17.4" "Group enriched" "Detected in some" 5 "Karpas-707: 21.0;RPMI-8226: 37.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "intermediate monocyte: 10.6;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 6 "monocytes: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003448, CAB010058" Supported 93000 "CAB010058: AB_668166, HPA003448: " "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 3.0 3.0 2.5 2.1 2.2 1.1 2.0 0.3 4.4 1.2 1.1 5.6 0.0 1.1 1.1 17.4 1.4 1.5 2.3 2.8 2.4 1.9 1.1 1.0 2.9 3.1 3.8 0.3 1.2 2.6 0.7 1.7 8.3 1.9 2.7 0.8 1.7 1.3 1.1 1.1 0.4 0.9 1.6 3.6 5.7 1.0 1.0 1.0 0.8 0.6 0.0 1.0 2.3 0.7 0.3 1.7 0.5 10.6 0.4 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.1 0.9 0.0 0.4 0.0 37.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.8 0.0 1.0 0.0 0.0 1.0 0.0 0.0 10.6 0.0 0.3 0.0 0.0 1.7 0.0 0.0 0.0 0.5 0.4 7.5 0.0 0.0 0.6 2.5 2.2 0.3 4.4 2.4 1.9 3.8 0.3 1.9 1.0 CRYBB2 "CCA2, CRYB2, CRYB2A" ENSG00000244752 "Crystallin beta B2" P43320 22 25219522-25231869 "Disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 26.9" "Cell line enhanced" "Detected in some" "HeLa: 5.1;THP-1: 1.7;U-138 MG: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043749 Supported Approved Nucleoplasm Nucleoplasm "HPA043749: " "unprognostic (1.28e-1)" "unprognostic (2.71e-2)" "unprognostic (4.09e-2)" "unprognostic (1.95e-1)" "unprognostic (5.06e-2)" "unprognostic (7.04e-2)" "unprognostic (8.57e-3)" "unprognostic (9.51e-3)" "unprognostic (8.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-3)" 0.8 0.7 2.0 0.5 3.7 0.1 1.7 0.5 1.8 1.0 1.3 0.5 0.5 0.8 0.5 1.8 1.1 0.4 0.5 0.6 2.9 1.5 0.5 0.5 1.4 0.5 0.8 0.5 0.5 0.5 0.0 2.6 0.5 0.9 0.9 1.5 26.9 1.2 0.5 0.6 0.4 1.0 1.0 0.5 0.5 0.2 4.0 0.5 0.5 1.7 0.5 0.5 0.5 0.5 1.4 1.3 0.5 1.1 1.7 1.4 0.7 0.2 0.5 0.1 0.7 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.8 0.0 0.0 0.2 0.0 1.1 0.6 5.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.3 1.2 0.3 0.6 0.0 0.2 0.1 0.6 0.0 0.2 0.0 0.8 1.7 0.0 2.9 0.7 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.5 0.8 0.4 1.4 0.6 0.6 1.4 1.2 0.7 1.1 1.0 1.1 1.2 0.1 1.7 1.1 1.3 0.4 0.7 2.0 3.7 0.5 1.8 2.9 1.5 0.8 0.5 0.9 0.5 CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199850-25207363 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HEK 293: 3.6;HeLa: 4.4;hTERT-HME1: 3.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA055840 Supported "HPA055840: " "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" 0.6 1.2 0.6 0.6 0.6 0.0 1.5 0.6 0.6 0.9 1.3 0.6 0.6 0.6 0.6 0.6 1.4 0.8 0.7 0.8 0.6 0.2 4.5 4.7 0.6 0.6 0.6 0.6 0.6 0.6 0.0 0.7 0.6 0.6 1.8 0.9 4.1 2.4 0.8 1.4 1.9 1.5 0.6 0.6 0.6 1.1 0.6 0.6 0.6 3.1 0.6 0.6 0.6 1.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.7 0.6 0.0 0.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.7 2.2 1.5 0.0 0.0 3.6 0.0 4.4 2.5 0.2 0.0 0.2 0.0 1.9 1.0 3.1 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.3 2.8 0.1 0.2 0.1 0.3 0.5 0.6 0.4 0.4 0.5 0.0 0.2 0.0 0.5 0.0 1.8 1.4 0.3 0.0 0.7 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.6 0.6 0.2 0.6 0.6 0.6 0.6 CRYGA "CRY-g-A, CRYG1, CRYG5" ENSG00000168582 "Crystallin gamma A" P11844 2 208160740-208163576 "Predicted intracellular proteins" "Eye lens protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.8" "Cell line enriched" "Detected in single" 5 "U-138 MG: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043386 Supported "HPA043386: " "unprognostic (1.49e-1)" 0.1 0.0 1.0 0.1 1.8 0.0 0.1 0.1 1.5 0.1 0.1 0.1 0.1 0.0 0.6 0.1 0.1 0.0 0.1 0.1 0.9 1.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 0.1 1.5 0.9 1.1 0.3 0.1 0.1 0.1 CRYGB CRYG2 ENSG00000182187 "Crystallin gamma B" P07316 2 208142573-208146168 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.7" "Cell line enhanced" "Detected in some" "MCF7: 1.1;NTERA-2: 2.8" "Group enriched" "Detected in some" 6 "ovarian cancer: 1.1;testis cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043386 Supported "HPA043386: " "unprognostic (6.73e-2)" "unprognostic (1.31e-1)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.5 0.3 0.9 0.0 0.0 0.0 CRYGC CRYG3 ENSG00000163254 "Crystallin gamma C" P07315 2 208128137-208129830 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.4" "Cell line enhanced" "Detected in some" "AF22: 1.0;CACO-2: 1.0;EFO-21: 2.0;U-2 OS: 1.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8;ovarian cancer: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043386 Supported "HPA043386: " "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 CRYGD CRYG4 ENSG00000118231 "Crystallin gamma D" P07320 2 208121607-208124501 "Disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 17.7" "Cell line enriched" "Detected in single" 19 "HEL: 15.0" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041269, HPA043386" Supported Approved "Plasma membrane,Intermediate filaments,Cytokinetic bridge" "Plasma membrane, Intermediate filaments" "Cytokinetic bridge" "HPA041269: , HPA043386: " "unprognostic (4.49e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" 0.2 0.2 4.2 0.2 2.0 2.3 0.2 0.0 2.5 0.2 0.2 0.3 0.0 0.4 0.2 0.2 0.3 0.3 0.2 0.6 2.1 4.3 0.2 0.2 0.2 0.2 4.0 1.6 17.7 0.2 0.2 0.4 0.5 1.9 2.0 0.2 2.1 0.2 0.2 0.2 0.2 0.4 0.2 0.4 0.2 0.5 1.4 0.5 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.2 2.0 0.0 2.5 2.1 4.3 4.0 1.6 1.9 0.5 CRYGS CRYG8 ENSG00000213139 "Crystallin gamma S" P22914 3 186538441-186546702 "Disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 15.1;cervix, uterine: 21.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035103, HPA063539" Supported Uncertain Cytosol Cytosol "HPA035103: AB_10696367, HPA063539: " "unprognostic (5.52e-4)" "unprognostic (1.29e-3)" "unprognostic (1.44e-2)" "unprognostic (5.45e-2)" "unprognostic (4.90e-2)" "unprognostic (5.85e-2)" "unprognostic (4.79e-2)" "unprognostic (1.73e-2)" "unprognostic (4.76e-2)" "unprognostic (1.12e-1)" "unprognostic (5.84e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.72e-9)" "unprognostic (1.10e-1)" "unprognostic (9.53e-2)" "unprognostic (3.67e-1)" "prognostic favourable (2.73e-4)" 1.6 1.9 3.6 1.8 2.7 4.0 3.4 15.1 3.3 21.8 1.8 3.5 1.6 1.7 2.7 3.8 1.6 1.3 1.6 1.6 4.1 4.1 2.2 1.8 2.6 4.2 4.2 1.6 2.2 1.8 1.9 1.6 1.6 3.0 1.6 3.7 5.8 1.8 2.9 1.6 3.0 1.8 2.3 3.2 3.6 2.4 1.8 1.6 6.0 1.6 3.2 3.3 1.6 1.6 0.3 0.6 0.2 0.2 0.0 2.1 0.1 1.0 2.0 3.7 3.1 3.6 5.6 0.5 0.5 1.2 1.3 2.5 0.4 1.5 3.8 4.1 2.7 3.2 1.7 2.8 5.5 3.2 4.9 5.0 1.4 1.9 1.4 2.9 3.4 5.9 3.8 1.2 2.1 4.2 1.0 2.2 3.0 1.2 2.6 1.5 0.2 1.6 4.3 0.8 1.8 1.5 2.3 1.7 1.6 2.6 2.5 1.0 2.0 1.7 4.5 1.4 1.1 1.6 2.7 4.6 2.3 5.3 1.9 1.9 2.7 0.0 0.2 0.0 1.4 0.0 2.1 0.3 1.9 0.8 0.4 0.1 0.2 0.4 0.2 0.0 0.0 0.6 0.2 0.1 3.6 2.7 15.1 3.3 4.1 4.1 4.2 1.6 3.0 1.6 GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161049 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.1;parathyroid gland: 6.2" "Cell line enhanced" "Detected in some" "A-431: 5.6;CAPAN-2: 10.1;HL-60: 8.3;U-266/84: 5.9" "Cancer enhanced" "Detected in some" "melanoma: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported "HPA014821: " "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.37e-2)" "unprognostic (2.58e-3)" "unprognostic (2.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.87e-3)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (7.52e-2)" "unprognostic (7.70e-2)" "unprognostic (4.02e-2)" "unprognostic (9.65e-8)" "unprognostic (2.87e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-2)" "unprognostic (8.04e-3)" 0.2 0.0 0.1 0.1 0.9 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.3 0.1 0.8 0.1 0.5 23.1 0.1 0.0 1.2 0.1 0.2 0.1 0.1 0.1 0.1 0.3 6.2 0.1 3.9 0.2 0.4 0.0 0.2 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.2 0.0 4.2 0.1 0.2 0.1 1.0 1.6 0.1 0.4 0.6 0.0 0.0 0.0 0.0 0.4 0.0 5.6 0.3 0.0 4.9 0.2 1.5 0.0 0.7 4.6 0.8 0.9 0.5 10.1 0.0 0.2 1.7 0.1 3.2 2.7 0.7 0.2 2.5 2.4 0.0 0.0 0.1 8.3 0.0 0.3 1.6 0.2 0.4 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.7 1.9 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.9 1.1 1.9 0.0 0.0 0.0 2.0 0.3 2.2 5.9 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 GJA8 "CAE, CAE1, CX50, CZP1" ENSG00000121634 "Gap junction protein alpha 8" P48165 1 147907956-147909257 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 76 "testis: 18.0" "Cell line enriched" "Detected in single" 13 "RPTEC TERT1: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014715, HPA062940" Enhanced "HPA014715: AB_2732411, HPA062940: AB_2732693" "unprognostic (3.73e-2)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867210 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;retina: 3.6;skin 1: 1.9" "Cell line enriched" "Detected in single" 6 "HeLa: 3.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA055217, HPA055835" Enhanced "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.9 0.1 3.3 0.1 0.1 1.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 1.0 3.6 0.1 0.1 0.1 1.9 3.3 0.1 0.1 0.1 0.4 0.7 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 3.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.1 0.0 0.1 0.1 0.1 0.1 LGSN "GLULD1, LGS" ENSG00000146166 "Lengsin, lens protein with glutamine synthetase domain" Q5TDP6 6 63275951-63319977 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 5.2;liver: 9.3" "Cell line enhanced" "Detected in some" "A549: 10.4;BEWO: 5.5;CACO-2: 3.3;HeLa: 3.8;Karpas-707: 2.6" "Cancer enhanced" "Detected in some" "lung cancer: 2.2" "Region enriched" "Detected in single" 7 "pons and medulla: 2.9" "Cell type enhanced" "Detected in some" "neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030957, HPA039983" Enhanced Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA030957: AB_10670149, HPA039983: AB_2676784" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (9.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (5.05e-4)" "unprognostic (1.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.53e-2)" "unprognostic (4.51e-3)" "unprognostic (1.64e-3)" "unprognostic (1.31e-1)" "unprognostic (2.19e-1)" 0.2 0.0 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 5.2 9.3 0.7 0.2 0.4 0.2 0.2 0.5 0.0 0.2 2.3 2.9 0.5 0.1 0.2 0.2 0.2 0.3 0.1 0.4 0.2 1.6 0.3 0.8 0.7 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.7 1.0 3.4 0.7 0.3 0.5 0.1 0.1 10.4 0.1 0.1 0.0 0.0 5.5 0.1 0.1 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.1 0.6 0.4 0.0 0.0 0.0 0.1 3.8 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.1 1.8 0.1 0.4 0.1 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.1 1.2 0.0 0.1 0.1 0.1 0.1 1.6 0.7 0.3 0.5 0.3 0.2 0.7 0.5 0.3 0.1 0.7 0.4 0.5 3.4 0.3 0.3 1.0 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.4 0.2 2.9 0.2 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111831 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 344.8" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" 59000000000 "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavourable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 44.8 25.3 0.8 15.1 0.7 0.0 19.7 0.7 0.7 56.7 26.9 0.7 28.1 5.1 64.8 77.8 28.1 12.2 76.6 48.8 0.8 0.7 26.9 6.4 77.1 32.0 0.9 0.6 73.0 9.1 0.7 2.7 344.8 2.8 77.4 13.3 1.4 5.6 9.9 9.1 8.3 24.0 48.7 4.0 1.3 8.2 30.9 0.3 1.7 18.1 32.3 11.5 65.3 20.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 22.5 11.1 0.0 36.9 182.3 1.5 2.3 0.0 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.3 0.0 17.6 0.0 0.0 15.2 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.4 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.7 0.7 0.8 0.7 0.9 0.6 2.8 0.3 MIP "AQP0, LIM1, MP26" ENSG00000135517 "Major intrinsic protein of lens fiber" P30301 12 56449502-56469166 "Disease related genes, Predicted membrane proteins" "Sensory transduction, Transport, Vision" "Eye lens protein" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 2.9;retina: 2.1;testis: 3.3" "Cell line enhanced" "Detected in some" "HEL: 2.7;SK-BR-3: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA014940 Supported "HPA014940: " "unprognostic (6.48e-2)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (7.14e-2)" "unprognostic (3.96e-2)" "unprognostic (2.90e-3)" "unprognostic (1.72e-1)" "unprognostic (3.47e-1)" "unprognostic (1.51e-5)" "unprognostic (4.56e-3)" "unprognostic (6.75e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-2)" "unprognostic (3.27e-1)" "unprognostic (2.62e-1)" "unprognostic (8.82e-2)" 0.2 0.4 0.4 0.2 0.5 0.1 0.2 0.3 0.7 0.2 0.2 0.2 0.2 0.5 0.2 0.2 0.2 0.0 0.2 0.4 0.5 0.8 0.2 2.9 0.2 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.3 2.1 0.2 0.2 0.2 0.1 0.2 0.2 0.6 0.2 0.0 3.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.1 1.3 1.0 1.4 0.3 0.6 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.6 0.1 0.0 0.3 0.8 0.0 0.2 0.9 0.1 0.1 0.2 0.2 0.0 0.0 0.6 0.3 2.7 0.2 0.0 0.1 0.8 1.8 0.1 0.0 0.3 0.1 0.0 0.3 1.7 0.4 0.4 0.0 0.9 0.6 0.6 0.0 0.1 0.7 0.3 0.4 1.5 0.5 0.9 2.5 0.7 0.5 1.8 0.2 0.4 0.3 0.0 0.0 0.1 0.2 0.9 0.0 0.8 0.3 1.0 1.4 0.1 0.6 0.8 0.3 0.7 0.6 0.2 0.0 1.1 0.2 0.4 0.6 0.3 0.3 1.3 0.5 0.0 0.4 0.5 0.3 0.5 0.5 0.8 0.4 0.2 0.2 0.2 OPTC ENSG00000188770 Opticin Q9UBM4 1 203494143-203508864 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "retina: 245.8" "Cell line enhanced" "Detected in some" "BJ: 1.0;HeLa: 1.5;NTERA-2: 2.5;RT4: 1.6;SCLC-21H: 1.2;U-2 OS: 1.0" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA034951, HPA034952" Enhanced "Secreted in other tissues" "HPA034951: AB_10669852, HPA034952: AB_2674379" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" "unprognostic (7.69e-2)" "unprognostic (3.19e-2)" "unprognostic (1.70e-3)" "unprognostic (8.24e-2)" "unprognostic (3.65e-2)" 0.3 0.0 0.2 0.1 0.2 0.0 0.2 0.4 1.0 0.4 1.3 0.1 0.1 0.4 1.3 2.2 0.8 0.8 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 1.1 0.3 0.0 0.1 0.4 0.1 0.7 0.3 245.8 0.1 0.6 0.1 1.1 0.2 1.1 0.1 0.1 0.1 2.6 0.1 0.1 0.2 0.1 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.3 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.7 0.0 0.1 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.1 0.1 0.2 0.2 0.1 0.1 0.1 PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393768-40413366 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 42.1;lung: 31.7;retina: 20.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "midbrain: 42.1" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enriched" "Detected in single" 21 "midbrain: 24.7" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: AB_2172440" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-2)" "unprognostic (9.72e-3)" "unprognostic (2.92e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" "unprognostic (2.03e-3)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (9.97e-2)" 3.4 4.4 4.8 1.0 4.1 1.1 2.7 2.2 5.4 3.0 2.3 1.8 2.8 1.2 3.8 2.0 2.2 3.2 2.4 2.9 4.0 2.2 4.3 0.6 31.7 1.3 42.1 3.7 7.5 5.4 7.3 1.1 6.0 10.3 3.2 0.8 20.6 3.9 4.4 5.4 2.2 1.5 3.3 11.0 1.7 2.4 1.6 3.6 0.0 7.2 6.7 0.9 3.1 2.0 0.3 0.4 0.0 0.3 0.1 1.2 0.2 2.4 2.7 3.3 4.2 2.7 7.0 4.1 2.0 2.3 2.9 2.1 2.3 2.7 0.8 2.6 1.9 1.3 1.1 0.9 1.0 1.2 1.4 0.5 0.9 0.7 3.2 0.2 3.6 4.9 4.9 1.9 1.6 1.5 3.0 0.8 1.5 3.2 1.1 0.8 0.7 2.5 4.8 2.7 2.4 0.5 1.3 0.3 1.5 3.9 3.3 3.0 4.9 1.2 2.2 5.9 4.6 2.3 1.2 8.4 7.3 1.1 1.8 1.3 1.3 0.0 0.3 0.0 0.6 0.2 0.2 0.0 0.4 0.6 0.0 0.3 0.3 1.2 0.0 0.1 0.0 0.4 0.3 0.2 4.8 4.1 2.2 5.4 4.0 2.2 42.1 3.7 10.3 3.6 TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028895-136063818 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 157.4;HSkMC: 164.3;hTCEpi: 114.3;LHCN-M2: 130.6;U-2197: 114.2;U-87 MG: 218.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "pons and medulla: 19.7" "Group enriched" "Detected in many" 30 "classical monocyte: 41.9;intermediate monocyte: 27.0;myeloid DC: 28.6;non-classical monocyte: 20.6;plasmacytoid DC: 61.2" "Group enriched" "Detected in many" 43 "dendritic cells: 61.2;monocytes: 41.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008612, HPA017019" Enhanced "Secreted to blood" 1400000000 "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavourable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favourable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavourable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavourable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" 51.3 16.6 1.8 30.4 3.9 4.3 32.2 1.1 6.5 14.1 24.2 5.2 16.2 9.2 30.2 71.9 21.1 15.2 94.9 53.0 4.1 2.9 21.7 47.5 42.5 65.1 3.7 2.4 27.0 10.5 3.3 23.7 90.0 19.7 27.0 16.9 21.8 21.1 13.1 24.1 63.8 22.4 56.5 10.1 41.6 21.2 18.2 2.1 21.2 12.0 40.1 18.8 46.3 24.4 0.2 61.2 0.9 41.9 1.2 0.3 15.1 5.7 23.5 0.0 0.2 66.5 21.9 0.0 17.6 2.2 12.1 7.3 10.6 74.0 0.0 10.7 157.4 28.4 0.0 56.6 10.8 0.1 0.0 0.0 28.2 28.5 44.5 0.0 0.2 164.3 114.3 4.5 5.1 10.3 0.0 0.2 130.6 0.2 0.0 0.0 0.7 0.0 0.0 1.2 0.1 5.7 0.5 0.0 0.0 27.7 0.9 0.2 0.2 6.3 43.3 82.3 3.5 114.2 62.7 0.0 0.0 0.0 218.6 0.0 62.7 0.2 41.9 0.1 0.1 27.0 0.2 0.2 0.2 0.3 28.6 0.0 0.0 0.2 0.9 1.2 20.6 61.2 0.1 15.1 1.8 3.9 1.1 3.0 4.1 2.9 3.7 2.4 19.7 2.1