Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814037-151828488 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.2;intestine: 81.7;liver: 123.1" "Cell line enhanced" "Detected in some" "A549: 11.7;ASC diff: 4.4;EFO-21: 6.3;HBEC3-KT: 5.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Region enriched" "Detected in single" 7 "basal ganglia: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favourable (5.58e-6)" "prognostic unfavourable (5.02e-4)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 3.9 66.2 0.1 0.1 1.6 0.0 2.1 0.1 0.1 0.1 26.1 0.5 0.4 29.6 0.1 0.3 0.3 0.2 4.3 0.2 0.1 0.0 0.1 123.1 1.7 0.1 0.1 0.1 0.1 22.7 0.0 0.1 1.7 0.2 0.3 0.0 0.1 0.3 0.1 0.2 1.7 81.7 0.1 0.1 0.1 7.3 0.3 0.1 0.1 0.2 4.8 1.3 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.4 0.2 0.3 0.0 0.0 0.1 0.0 1.1 0.1 0.2 6.3 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.7 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.2 0.3 0.2 0.4 2.1 0.0 2.2 0.2 1.9 0.3 0.1 0.0 0.0 0.0 2.5 0.0 2.4 1.3 0.0 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 109.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavourable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 5.1 5.9 11.0 5.7 11.9 7.8 6.9 25.2 26.5 4.8 4.2 3.9 6.3 3.8 4.7 7.1 3.8 4.9 4.3 7.9 14.4 12.8 7.2 3.1 7.5 6.8 9.4 11.6 3.3 6.7 109.7 10.3 6.9 10.2 5.0 4.6 4.7 3.6 12.3 6.8 3.7 3.7 5.4 9.3 5.5 5.4 4.1 6.9 4.7 16.0 2.1 5.3 4.9 5.8 1.0 0.8 4.1 3.9 2.8 5.6 1.3 16.5 9.9 9.1 8.8 8.7 9.7 29.3 13.5 10.7 8.2 7.2 10.0 6.6 0.5 3.3 17.5 7.7 7.0 7.0 16.7 12.3 2.9 9.0 6.0 6.8 7.9 6.3 21.4 8.3 6.2 15.4 19.9 17.3 1.9 9.3 14.2 2.8 5.8 3.3 4.4 5.5 3.9 9.9 1.4 6.4 34.7 3.0 4.8 7.8 6.0 7.0 3.5 8.9 17.2 18.3 12.3 13.1 13.2 9.2 2.4 1.0 15.3 10.7 12.5 2.5 1.4 0.6 4.5 0.6 4.2 0.4 4.0 3.0 0.8 1.0 5.6 4.5 4.1 2.8 3.9 0.7 3.1 1.3 11.0 11.9 25.2 26.5 14.4 12.8 9.4 11.6 10.2 6.9 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81117295-81166077 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;intestine: 28.7" "Group enriched" "Detected in some" 6 "CACO-2: 29.6;SH-SY5Y: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "neutrophil: 3.6" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 2.8 4.7 14.3 3.2 16.6 3.7 0.9 19.0 29.0 1.2 3.3 16.5 0.0 28.7 1.0 1.1 1.7 1.2 2.7 2.3 23.6 13.9 1.2 1.2 9.7 1.5 20.1 13.6 1.0 17.9 3.6 6.4 2.6 11.0 2.4 1.1 4.1 5.6 3.6 1.1 1.9 20.3 1.3 35.3 5.9 4.5 1.3 9.8 0.0 1.3 0.0 1.0 1.3 1.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 29.6 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 1.6 1.1 1.4 1.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.1 0.0 0.1 0.5 0.1 1.3 2.4 0.2 0.0 0.0 2.8 10.2 0.2 0.0 1.4 0.3 0.8 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 14.3 16.6 19.0 22.3 23.6 13.9 20.1 13.6 11.0 9.8 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 205.6" "Group enriched" "Detected in some" 4 "ASC TERT1: 35.9;HUVEC TERT2: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "memory B-cell: 3.7" "Group enriched" "Detected in many" 23 "B-cells: 3.7;monocytes: 2.0;T-cells: 1.9" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" 121920000 92000000 Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: " "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 6.8 2.0 0.5 2.4 4.2 0.0 2.9 0.5 1.1 5.3 83.2 0.7 37.7 46.4 4.5 5.1 1.7 1.5 4.4 4.7 0.6 0.7 2.6 1.4 16.3 2.2 0.4 0.7 1.4 3.0 3.6 3.6 3.6 0.8 3.4 1.4 1.7 2.5 20.1 3.6 1.3 205.6 2.4 0.6 1.4 1.9 32.6 1.3 0.5 6.9 3.1 2.2 1.7 1.6 3.7 0.1 0.0 2.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 1.5 35.9 0.4 1.3 2.6 0.0 0.0 0.5 3.1 0.7 1.0 6.1 0.0 1.7 0.0 0.0 0.0 0.7 3.4 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 18.3 3.0 0.0 0.0 0.6 0.0 0.7 0.2 0.3 0.1 0.2 0.5 0.0 0.0 4.5 3.2 0.0 0.0 0.0 1.6 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.9 3.7 1.9 1.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.5 4.2 0.5 1.1 0.6 0.7 0.4 0.7 0.8 1.3 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15561033-15602148 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 122.0" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HaCaT: 4.1;Hep G2: 2.4;NB-4: 2.2;RPMI-8226: 2.0;RT4: 2.4;SH-SY5Y: 2.8" "Cancer enhanced" "Detected in many" "renal cancer: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174" Enhanced "Secreted to blood" 85000 "CAB026174: , HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favourable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favourable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 4.5 0.4 0.2 0.8 0.2 0.0 2.3 0.2 0.2 0.4 49.1 0.2 2.3 46.0 0.4 2.7 1.2 0.6 16.4 10.5 0.2 0.1 23.2 1.2 0.8 0.6 0.2 0.2 1.3 1.6 0.0 0.2 1.0 0.2 0.5 1.3 0.2 1.1 1.2 0.7 0.2 122.0 0.3 0.2 0.2 0.5 17.9 0.2 0.2 4.5 0.5 0.2 0.4 0.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.4 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.6 0.0 4.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.0 0.0 2.0 0.4 2.4 0.6 2.8 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157875862 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: " "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.17e-4)" 18.9 9.2 18.0 10.0 12.7 1.6 38.7 15.3 12.2 25.2 14.4 7.4 8.4 8.9 24.8 26.8 11.0 16.6 20.5 18.8 18.7 8.6 21.7 18.9 22.5 15.1 10.4 7.9 18.5 12.3 11.3 17.0 14.2 12.3 16.8 10.5 14.3 18.1 13.6 15.6 12.8 11.5 29.2 12.3 9.2 11.8 8.8 10.9 7.5 34.0 14.6 6.9 16.1 32.5 1.4 2.4 3.8 2.6 1.9 10.0 1.6 2.1 4.2 4.9 6.4 25.0 26.1 6.9 15.1 25.2 12.1 13.0 3.3 4.7 0.0 7.0 16.4 5.9 3.5 8.2 13.1 14.5 3.0 8.6 2.5 4.8 19.8 0.6 10.2 32.6 15.6 24.9 31.8 13.2 3.1 2.4 15.3 3.7 0.1 0.2 7.4 7.7 1.4 6.6 1.8 15.8 7.9 4.4 5.4 5.8 3.3 20.7 1.7 2.3 19.0 18.5 6.1 9.1 5.7 1.6 1.2 0.1 19.0 0.5 19.9 3.8 2.6 0.2 1.1 1.7 1.2 1.4 7.8 2.5 1.8 0.8 3.1 1.5 0.8 1.9 2.3 2.4 10.0 1.6 18.0 12.7 15.3 12.2 18.7 8.6 10.4 7.9 12.3 10.9 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol Cytosol "CAB026126: , HPA063761: " "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.2 13.8 10.7 5.9 12.3 9.7 6.1 7.1 8.1 7.6 5.8 27.8 9.7 2.7 10.0 7.7 11.1 10.2 8.6 7.9 4.0 12.0 6.8 3.5 8.6 14.1 10.9 25.5 18.9 11.2 8.6 10.9 10.7 7.2 8.6 6.7 12.8 10.4 9.5 10.4 4.8 5.6 8.3 3.5 21.5 9.6 13.7 11.4 7.7 11.0 5.0 12.1 7.1 6.7 5.2 8.0 5.9 3.4 5.2 3.7 3.8 5.6 5.3 6.7 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Group enriched" "Detected in some" 4 "ASC diff: 15.1;HDLM-2: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.1 15.1 0.4 0.3 0.4 0.4 0.1 0.5 2.2 0.2 0.0 0.2 1.2 0.0 0.1 0.0 0.3 6.6 1.0 0.0 0.0 0.5 0.0 0.0 1.1 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 1.3 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 20.5;RH-30: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favourable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 12.0 6.0 13.6 8.2 9.9 3.8 10.7 14.5 14.2 10.2 14.1 4.7 9.7 10.4 9.3 9.9 13.6 7.6 17.7 5.6 10.0 9.0 9.0 10.3 7.5 4.7 5.9 10.6 7.6 9.8 8.6 15.9 10.6 7.3 12.2 9.1 7.6 12.2 12.0 19.6 29.5 17.8 13.8 5.4 6.5 9.3 11.0 6.4 1.5 9.5 6.9 6.8 13.5 11.8 0.7 3.0 0.5 3.6 7.7 4.6 1.4 1.3 1.5 9.8 3.6 5.8 3.7 4.0 3.0 3.6 5.2 9.1 4.2 5.9 0.0 2.7 4.8 4.6 8.9 4.4 6.7 1.0 5.4 0.6 2.7 7.3 20.5 0.6 0.7 6.2 5.6 3.3 6.7 3.9 1.4 2.5 3.5 3.4 0.3 0.5 11.0 2.6 0.1 17.1 0.9 4.2 8.3 9.7 5.5 2.5 3.1 3.7 1.9 1.0 3.0 4.8 5.7 4.5 2.1 0.7 0.2 1.8 3.0 0.3 3.8 0.4 3.0 0.5 1.2 3.6 0.5 0.3 4.6 2.1 2.3 0.7 3.0 0.7 0.1 7.7 3.1 3.0 0.4 1.4 13.6 9.9 14.5 14.2 10.0 9.0 5.9 10.6 7.3 6.4 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 16.6;NTERA-2: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "CAB025115: , HPA007398: , HPA040384: " "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.6 1.4 0.6 0.4 8.9 0.3 0.5 0.3 0.7 2.4 1.1 0.1 1.3 0.4 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.6 3.5 0.8 3.0 1.6 0.7 0.9 0.5 1.8 1.1 7.0 1.4 0.3 1.3 5.1 1.9 20.5 0.7 1.7 5.5 1.0 1.1 2.0 3.9 6.8 0.5 2.5 2.2 1.4 4.0 0.9 0.6 2.7 0.4 1.4 4.0 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.0" "Cell line enhanced" "Detected in some" "ASC diff: 18.1;ASC TERT1: 12.4;EFO-21: 16.0;HUVEC TERT2: 58.5;TIME: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 3.6;myeloid DC: 5.0" "Group enriched" "Detected in many" 12 "dendritic cells: 5.0;monocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 25.5 5.1 3.2 9.3 4.3 0.2 15.6 1.6 3.6 15.1 20.1 3.7 13.1 4.9 12.7 11.0 12.1 13.9 11.0 15.4 3.7 3.2 13.6 3.4 55.0 19.1 4.9 3.6 5.9 6.1 21.6 2.7 44.1 5.3 12.3 14.7 12.3 6.9 10.6 14.2 8.0 11.1 8.2 3.7 14.8 8.1 3.5 3.6 1.7 12.9 6.8 5.4 9.3 11.2 0.1 5.0 0.3 3.6 0.0 0.1 0.7 0.0 0.2 0.1 0.0 18.1 12.4 0.0 0.8 1.6 0.0 0.0 0.1 0.1 0.0 16.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 2.7 0.0 0.4 5.0 0.0 0.1 0.0 58.5 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 45.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.7 3.2 4.3 1.6 3.6 3.7 3.2 4.9 3.6 5.3 3.6 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430770-177442503 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 31.5;Karpas-707: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" 28000000 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (8.61e-4)" "prognostic unfavourable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 12.8 15.1 11.2 11.2 11.9 10.9 18.5 4.4 13.7 13.5 12.1 24.2 8.0 8.0 9.8 26.4 18.8 7.1 15.1 8.4 13.0 9.4 20.5 26.5 12.4 12.3 14.0 11.0 10.2 14.7 19.2 9.0 9.3 15.0 10.1 11.1 24.0 27.1 10.8 6.7 16.9 14.4 8.1 22.3 14.9 13.0 13.3 10.0 13.4 14.0 14.3 18.3 9.0 10.2 10.0 11.1 16.3 23.8 8.9 16.3 10.3 2.0 4.6 5.3 7.6 6.3 5.6 3.6 15.5 31.5 8.0 10.2 2.4 10.3 10.3 2.9 11.9 2.5 4.5 5.1 16.3 6.6 2.9 4.3 5.1 6.7 4.1 7.5 3.0 4.0 8.9 5.9 2.7 7.6 3.8 44.6 3.3 5.7 6.0 4.7 2.0 4.8 1.9 2.2 1.5 8.5 5.2 2.9 6.7 4.6 4.0 12.3 9.1 15.4 2.3 5.6 5.0 2.6 5.9 8.6 6.6 5.5 9.0 8.5 6.2 15.0 10.7 16.3 11.7 18.9 13.4 10.0 12.8 14.0 10.5 8.1 11.4 16.3 2.4 8.9 23.8 11.1 12.0 10.3 11.2 11.9 4.4 13.7 13.0 9.4 14.0 11.0 15.0 10.0 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favourable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favourable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.1 30.3 25.0 37.2 19.4 20.1 28.0 27.9 34.0 41.3 33.1 19.8 18.3 18.3 21.5 38.2 19.7 17.7 26.0 18.0 41.8 7.2 13.9 18.1 21.3 21.5 22.6 36.3 28.8 21.9 20.7 13.8 30.8 12.1 20.4 26.4 113.2 28.4 28.9 6.5 21.7 26.8 23.2 12.5 19.1 37.7 28.7 23.9 23.3 30.5 17.5 39.9 33.7 24.6 27.7 13.3 39.4 28.0 22.2 10.7 15.8 23.3 19.1 33.3 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: " "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.4 55.4 21.1 21.7 26.3 32.2 11.7 15.0 22.2 31.1 27.8 24.3 20.9 22.9 13.4 33.1 9.8 23.4 31.3 20.1 21.9 26.7 15.0 35.1 15.3 16.5 17.2 18.1 29.7 18.8 21.1 20.1 6.7 19.3 24.0 17.3 18.7 27.3 8.4 11.4 14.9 18.2 11.5 16.5 24.2 36.8 29.1 17.8 15.4 26.4 12.5 20.8 22.2 6.7 19.0 18.8 17.0 23.5 22.4 19.2 18.8 18.6 20.4 15.5 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavourable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.5 2.4 14.9 0.0 11.0 12.6 7.9 13.3 12.2 8.6 7.6 0.1 9.7 0.0 0.0 16.8 0.3 8.2 5.3 11.4 5.9 6.4 0.3 0.0 0.0 5.7 0.1 2.6 6.5 0.0 10.7 9.7 17.6 0.0 0.1 3.9 0.0 5.0 1.1 6.3 3.7 2.7 9.1 0.1 2.9 0.8 19.1 25.3 0.1 0.0 23.8 0.0 8.0 13.8 15.3 11.8 0.1 11.0 1.3 0.4 2.8 11.2 1.2 12.8 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605929-95656706 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 68.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Supported Mitochondria 23000 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favourable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavourable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 6.3 10.4 7.1 10.4 7.9 5.2 7.7 7.3 9.3 13.7 20.1 7.2 20.5 33.8 9.3 12.3 12.8 8.5 15.2 7.2 6.2 7.1 13.0 28.9 6.6 7.4 6.7 5.3 14.5 40.7 12.7 17.4 14.3 7.7 9.6 19.4 7.9 68.8 20.5 3.5 9.6 45.4 10.0 5.4 8.6 15.2 8.4 5.4 12.7 25.9 9.7 15.9 8.6 8.2 13.1 5.2 0.3 4.0 13.0 16.3 8.0 18.2 17.3 16.6 43.6 22.4 21.7 17.9 21.3 32.1 21.7 27.3 34.6 14.6 62.1 20.0 33.5 24.2 33.3 21.9 24.7 17.6 26.2 19.7 12.3 49.1 14.7 34.3 22.0 22.7 13.5 17.7 34.7 22.7 18.3 13.1 16.2 26.2 31.0 22.1 19.6 17.3 29.2 19.1 21.3 25.3 13.9 16.6 16.5 16.9 13.5 15.7 20.1 16.0 18.8 9.0 14.4 23.2 24.4 15.1 11.2 38.0 17.6 39.8 11.5 0.0 1.4 0.1 15.5 2.7 16.3 13.1 14.2 16.0 5.2 9.0 12.1 13.4 0.3 13.0 4.0 3.1 13.3 8.0 7.1 7.9 7.3 9.3 6.2 7.1 6.7 5.3 7.7 5.4 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392664-38398661 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 113.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021037 Approved Supported Nucleoplasm,Vesicles,Mitochondria 210000 Mitochondria "Nucleoplasm, Vesicles" "HPA021037: AB_1844724" "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favourable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (2.89e-2)" 7.4 4.9 2.1 16.8 2.1 0.6 5.4 1.1 5.4 5.8 25.4 1.7 6.1 7.0 27.3 10.7 21.6 16.7 30.8 11.6 3.1 2.0 18.0 55.2 3.5 5.9 2.4 2.0 12.2 14.6 1.4 1.4 1.6 3.0 22.7 11.5 5.2 5.9 18.2 19.4 3.0 11.2 113.9 2.7 2.8 15.8 7.8 1.7 1.6 6.3 7.0 2.0 54.5 8.3 5.9 9.4 1.2 10.5 7.5 10.2 5.1 23.9 22.3 6.9 11.0 9.8 11.7 5.5 11.5 5.8 9.7 10.0 14.9 4.7 15.1 6.9 16.1 3.4 22.7 24.3 9.7 16.9 9.8 7.5 16.4 44.2 7.1 11.9 8.5 13.9 5.3 7.9 6.9 9.2 21.6 14.8 14.7 9.1 0.0 4.8 20.5 10.0 4.9 41.8 11.5 8.7 10.8 15.1 7.0 8.7 5.8 6.7 5.5 9.3 6.2 11.2 18.6 9.3 14.3 2.2 4.3 6.0 5.8 12.2 7.6 0.2 4.2 0.2 7.3 9.1 10.2 5.9 7.0 6.6 9.4 3.1 5.8 6.8 1.2 7.5 10.5 1.3 4.8 5.1 2.1 2.1 1.1 5.4 3.1 2.0 2.4 2.0 3.0 1.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family (mitochondrial)" P05091 12 111766887-111817529 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;HHSteC: 29.4;SK-BR-3: 59.1;THP-1: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 45.8;myeloid DC: 46.6" "Group enriched" "Detected in many" 4 "dendritic cells: 46.6;monocytes: 45.8" HPA051065 Approved 1400000 "HPA051065: " "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favourable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favourable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favourable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavourable (7.71e-4)" 88.9 34.0 42.1 17.0 44.6 9.9 39.6 14.3 30.9 10.4 25.3 17.5 16.8 25.6 9.0 11.6 26.4 10.3 28.5 45.0 30.9 24.2 59.0 279.7 38.1 13.3 34.1 32.6 16.1 14.0 2.2 7.6 4.0 30.6 13.5 26.2 13.1 17.9 30.7 40.1 43.5 25.5 29.4 26.6 8.0 34.9 9.5 23.8 3.3 12.0 28.1 18.2 17.0 22.9 1.4 46.6 10.8 45.8 0.7 0.2 21.7 2.4 3.8 5.5 9.4 26.2 3.9 18.0 2.6 4.9 1.2 0.9 6.7 3.5 0.1 13.5 5.9 4.7 0.0 1.3 0.8 0.1 1.8 0.2 2.4 18.2 29.4 0.2 0.2 7.2 6.7 4.4 0.1 7.8 4.9 0.8 1.2 0.1 0.2 6.6 7.3 0.6 0.1 0.1 0.5 9.1 0.1 2.2 6.8 6.6 59.1 0.0 5.9 26.3 0.3 0.1 5.0 0.1 0.1 1.6 0.8 7.1 6.5 0.2 0.1 0.9 45.8 10.8 0.1 20.1 0.2 1.4 0.0 0.1 46.6 1.2 0.1 0.1 2.3 0.7 5.0 15.5 0.1 21.7 42.1 44.6 14.3 30.9 30.9 24.2 34.1 32.6 30.6 23.8 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19677598 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Approved "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favourable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 22.3 66.4 8.5 9.0 24.6 2.8 10.0 8.8 12.8 13.7 15.9 17.5 7.5 15.6 13.5 19.2 39.6 10.7 26.4 12.5 9.5 6.5 52.5 88.6 17.7 4.3 11.1 10.3 13.5 24.4 10.1 14.9 3.1 14.4 20.7 11.1 16.2 26.0 10.0 18.5 57.1 26.6 10.5 10.2 8.0 18.3 9.8 15.4 4.5 27.3 27.9 22.5 9.8 17.0 3.9 14.3 11.6 14.2 8.6 6.4 5.7 6.7 42.3 4.2 10.6 20.2 17.1 2.9 2.0 5.2 4.0 4.6 13.2 11.0 2.1 4.9 8.4 15.1 16.6 20.3 2.9 9.4 7.2 1.0 22.3 32.3 3.8 5.0 0.5 9.4 28.9 3.8 2.3 8.0 0.2 0.1 10.1 9.1 0.1 6.2 10.1 23.2 4.9 12.1 6.4 4.7 21.4 8.2 5.8 18.5 7.1 5.9 12.4 4.6 9.5 2.6 4.7 6.8 6.3 2.9 7.2 3.0 12.6 0.0 8.4 0.0 14.2 11.6 4.2 12.6 6.4 3.9 4.3 3.7 14.3 3.0 4.9 3.4 0.7 8.6 13.7 0.2 5.8 5.7 8.5 24.6 8.8 12.8 9.5 6.5 11.1 10.3 14.4 15.4 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595418 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023296 Enhanced Supported Mitochondria,Cytosol 140000 Mitochondria Cytosol "HPA023296: AB_1844738" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favourable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 9.0 14.2 46.0 3.4 39.1 0.8 18.8 11.0 22.5 14.0 11.5 23.1 7.2 9.5 10.5 7.5 13.5 11.9 7.8 10.8 35.0 17.3 46.5 64.4 6.4 3.1 28.7 18.5 27.6 10.8 17.7 5.9 17.7 16.9 17.6 11.2 13.7 15.0 12.2 4.5 11.9 8.1 9.8 20.2 2.8 9.0 4.9 28.4 4.0 19.4 10.1 7.4 7.2 7.1 1.3 9.7 0.7 0.3 0.1 1.8 0.6 14.8 9.8 27.8 46.0 23.2 13.8 35.5 17.8 22.0 20.7 26.8 27.6 14.3 0.0 18.2 13.9 11.1 8.6 60.2 19.1 0.0 10.4 2.8 14.7 23.4 11.3 0.0 0.0 16.9 14.2 16.1 11.6 16.5 0.0 0.0 18.2 9.7 0.6 0.0 18.8 8.3 8.9 31.6 0.0 19.7 11.3 9.5 11.3 0.0 9.8 10.3 17.7 0.6 20.0 6.0 18.6 6.9 12.2 0.0 0.0 0.0 3.2 0.0 9.6 0.7 0.3 0.1 0.2 0.0 0.3 1.3 0.3 0.2 2.7 1.1 1.8 1.0 0.3 0.1 0.0 9.7 0.1 0.6 46.0 39.1 11.0 22.5 35.0 17.3 28.7 18.5 16.9 28.4 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" 1100000 Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favourable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 39.1 52.7 30.8 17.4 25.4 7.7 39.6 16.2 26.6 20.3 18.0 22.7 17.1 19.5 15.5 35.5 47.0 18.8 22.2 22.2 24.8 21.1 50.5 73.5 20.7 20.4 23.7 18.4 20.6 17.8 31.2 19.2 14.1 22.8 24.6 18.7 27.2 52.2 23.2 29.9 22.6 23.9 19.2 21.9 18.8 14.7 37.3 21.5 12.4 45.1 24.2 27.9 18.5 19.1 29.6 20.2 29.4 24.5 23.1 39.0 24.4 17.4 17.1 16.0 14.3 51.2 45.1 13.4 23.2 32.9 23.3 20.3 10.6 13.2 0.0 22.2 20.7 13.8 12.9 22.6 27.7 8.1 16.4 11.1 12.3 11.5 26.4 17.5 11.9 28.9 11.5 24.7 20.8 20.2 17.6 15.8 36.3 10.5 11.6 18.0 23.3 21.1 10.0 20.4 23.4 30.3 16.6 19.0 13.1 16.5 18.6 21.2 35.5 26.6 19.9 14.1 13.8 17.2 11.7 14.7 19.2 17.5 15.9 16.7 13.5 26.8 20.3 28.1 28.3 21.5 30.1 29.6 27.7 30.6 20.2 26.0 28.1 32.0 29.4 23.1 24.5 12.6 39.0 24.4 30.8 25.4 16.2 26.6 24.8 21.1 23.7 18.4 22.8 21.5 AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425538 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: , HPA077835: " "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" 13.9 25.9 21.3 10.6 23.8 14.1 28.7 12.6 25.0 17.2 21.0 24.5 18.5 21.6 16.6 25.2 20.8 15.3 13.7 17.6 20.6 20.2 35.2 50.0 13.3 19.3 22.3 14.3 20.5 14.0 33.3 13.0 41.6 18.9 14.9 11.8 23.8 12.6 18.6 71.6 11.9 18.8 16.0 25.0 14.3 12.2 36.8 17.5 14.6 18.6 10.1 19.3 15.5 16.9 18.3 10.6 21.4 13.1 11.7 9.7 4.0 17.4 24.4 10.7 19.6 33.4 18.8 9.4 18.9 23.4 25.7 20.2 21.6 16.6 45.6 21.9 25.5 16.4 16.3 14.7 24.6 10.2 16.8 13.8 10.1 23.2 29.3 10.7 16.0 21.8 21.3 20.5 24.6 14.9 14.3 6.3 18.6 11.1 16.0 11.4 5.0 16.8 18.1 21.5 17.1 15.9 18.3 10.7 8.2 44.4 15.6 14.3 46.9 11.2 19.3 24.3 13.3 12.3 12.7 13.6 11.9 24.2 17.6 7.8 11.1 21.4 8.5 10.9 6.9 9.9 9.7 18.3 8.7 7.1 7.8 15.6 9.1 9.5 10.5 11.7 13.1 10.6 9.0 4.0 21.3 23.8 12.6 25.0 20.6 20.2 22.3 14.3 18.9 17.5 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 27.1;ovary: 38.2;testis: 15.2" "Group enriched" "Detected in some" 18 "HEL: 27.6;K-562: 15.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "hippocampal formation: 14.3" "HPA060228, HPA069636" Approved "Nucleoplasm,Vesicles,Centriolar satellite,Cytosol" Vesicles "Nucleoplasm, Centriolar satellite, Cytosol" "HPA060228: , HPA069636: " "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.3 27.1 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.0 0.3 0.6 0.4 0.2 0.4 0.8 0.2 0.0 0.2 1.1 0.3 0.2 0.2 0.2 38.2 8.8 0.1 0.2 0.2 0.3 0.4 0.0 0.2 0.2 0.2 2.5 0.0 0.4 0.5 0.2 3.7 0.3 15.2 0.2 0.2 0.2 0.5 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 27.6 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.2 ANKRD1 "ALRP, C-193, CARP, CVARP, MCARP" ENSG00000148677 "Ankyrin repeat domain 1" Q15327 10 90912096-90921276 "Disease related genes, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 81 "heart muscle: 398.9;skeletal muscle: 333.3" "Cell line enhanced" "Detected in some" "CACO-2: 37.6;EFO-21: 103.9;HUVEC TERT2: 35.4;LHCN-M2: 127.6;TIME: 177.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038736 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA038736: " "unprognostic (2.45e-1)" "unprognostic (6.14e-3)" "unprognostic (2.24e-1)" "unprognostic (4.39e-1)" "unprognostic (9.14e-3)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.28e-2)" "unprognostic (6.63e-3)" "unprognostic (2.19e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (3.40e-1)" "unprognostic (2.72e-5)" "unprognostic (3.40e-2)" "unprognostic (2.79e-1)" "unprognostic (7.22e-2)" "unprognostic (3.16e-3)" 1.5 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.1 1.5 0.1 0.1 398.9 0.0 0.0 0.1 0.1 4.5 0.2 0.0 0.0 0.1 0.4 0.1 0.1 0.7 0.1 0.9 0.1 0.0 0.8 0.1 333.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 2.9 1.6 0.5 0.3 0.0 0.4 0.5 1.9 0.6 0.9 0.4 0.2 2.9 0.8 0.5 0.0 0.4 0.5 0.0 1.7 0.1 0.4 0.9 37.6 1.4 0.0 103.9 0.1 1.0 0.1 0.2 1.3 0.1 0.1 0.0 0.2 11.6 2.3 0.0 0.0 3.7 0.0 0.7 1.8 35.4 0.0 0.0 127.6 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 177.6 0.3 13.6 0.2 13.9 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.2 0.5 0.2 0.3 0.3 0.3 0.2 0.2 0.2 0.4 0.4 0.3 0.7 0.9 0.6 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551519-78610451 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.0" "Cell line enhanced" "Detected in many" "A-431: 52.0;CACO-2: 53.3;CAPAN-2: 72.2;EFO-21: 44.2;hTERT-HME1: 73.6;RPTEC TERT1: 62.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 319 "neutrophil: 51.3" "Lineage enriched" "Detected in single" 319 "granulocytes: 51.3" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Enhanced Cytosol 7400000 Cytosol "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavourable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favourable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 20.3 1.1 4.0 7.1 7.4 83.0 16.2 2.4 6.8 7.0 8.5 2.3 0.9 4.2 3.4 4.2 25.0 4.6 11.7 20.5 5.2 5.2 19.8 1.6 46.0 5.7 6.6 5.6 2.8 14.7 6.5 5.8 33.7 10.4 18.8 7.4 2.6 50.8 3.6 14.2 4.1 9.3 5.3 4.0 11.0 23.4 1.8 5.0 2.0 45.3 13.6 7.4 2.8 5.9 0.1 0.0 51.3 0.1 0.0 0.0 0.5 52.0 9.9 0.1 0.1 0.1 0.2 0.0 0.6 0.0 1.5 1.4 53.3 72.2 0.0 44.2 1.8 20.6 0.0 38.1 2.3 0.2 0.4 4.6 21.3 3.2 6.1 0.6 0.0 0.3 33.8 0.5 73.6 15.1 0.1 0.0 0.2 2.0 0.2 0.0 1.6 7.3 0.0 0.1 0.0 62.0 6.0 0.0 0.0 30.7 7.6 2.2 1.3 0.6 19.1 0.1 6.9 0.0 11.7 0.4 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 51.3 0.0 0.1 0.0 0.0 0.5 4.0 7.4 2.4 6.8 5.2 5.2 6.6 5.6 10.4 5.0 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512949-36724549 "Enzymes, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 54.6;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "NB-4: 20.9;THP-1: 16.0;U-937: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 54.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021666, HPA026716" Approved "Secreted to blood" "HPA021666: , HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 8.4 3.4 5.2 17.2 4.9 19.3 2.8 1.9 3.6 3.1 5.3 7.4 0.2 4.9 3.9 7.2 2.5 3.1 8.4 3.4 4.8 3.8 3.1 6.8 9.4 23.2 6.9 2.0 2.1 2.3 0.6 2.4 5.7 5.8 3.8 7.3 3.8 4.5 1.4 1.5 1.6 7.6 4.7 12.6 57.4 3.3 1.4 6.8 14.0 2.9 0.4 10.9 7.2 2.8 0.3 34.8 18.7 54.6 19.2 8.8 31.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.9 0.0 0.3 0.1 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 20.9 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.3 54.6 17.6 8.8 47.9 1.8 0.3 0.4 6.1 34.8 0.0 1.0 7.8 18.7 19.2 20.2 0.5 0.1 31.0 5.2 4.9 1.9 3.6 4.8 3.8 6.9 2.0 5.8 6.8 AOC1 "ABP1, DAO" ENSG00000002726 "Amine oxidase, copper containing 1" P19801 7 150824627-150861504 "Enzymes, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.6;placenta: 240.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.0;HaCaT: 4.9;NB-4: 4.8;RPMI-8226: 5.8;THP-1: 20.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "eosinophil: 20.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 20.3" "Low region specificity" "Detected in all" "HPA031032, HPA031033" Approved "Secreted in other tissues" 800000 "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favourable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.3 0.3 0.3 6.7 0.3 0.0 0.3 0.3 0.3 0.9 68.3 0.2 1.2 30.2 0.3 3.9 1.7 0.3 4.4 0.3 0.3 0.3 37.9 1.5 0.3 0.6 0.3 0.1 0.3 0.6 0.0 0.3 240.4 0.1 1.3 15.5 0.1 0.4 0.2 0.3 0.8 108.6 0.2 0.3 0.4 2.7 1.8 0.1 0.7 0.3 0.1 1.0 0.4 0.4 0.0 1.0 20.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.1 0.0 0.0 0.0 2.5 16.0 0.0 2.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 4.8 0.2 0.0 0.0 0.0 5.8 0.2 0.1 1.8 2.1 0.0 0.7 0.0 0.6 20.9 0.5 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.1 0.1 20.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.1 0.1 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase, copper containing 2" O75106 17 42844600-42850707 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 133.5" "Cell line enhanced" "Detected in many" "ASC diff: 14.3" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 4 "neutrophil: 4.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA057779 Uncertain "Intracellular and membrane" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favourable (2.47e-4)" 11.6 1.2 0.9 1.3 3.2 1.8 3.1 3.2 1.6 1.5 1.1 0.9 0.9 0.6 1.5 1.2 1.0 1.5 1.5 1.3 1.2 1.8 0.9 3.6 2.2 1.0 0.9 0.9 1.0 1.2 0.8 2.1 0.9 0.9 1.3 0.5 133.5 1.2 1.2 1.4 1.2 1.0 1.3 1.0 1.7 0.7 6.5 0.9 1.0 1.0 0.9 1.2 1.6 0.9 0.1 0.0 4.0 0.0 0.0 0.6 0.0 0.2 2.8 0.6 3.1 14.3 1.4 7.4 0.9 0.9 2.0 2.8 2.2 0.3 1.1 1.4 0.3 1.2 2.7 0.7 4.1 2.3 7.3 0.4 1.3 2.2 0.9 0.4 2.8 2.2 2.5 1.9 2.9 0.5 0.7 2.6 0.6 0.3 0.6 1.1 1.1 0.9 1.4 2.8 2.2 0.4 4.4 1.0 0.6 0.1 1.0 4.0 0.5 0.2 0.5 1.9 4.0 2.5 1.2 5.7 5.5 1.1 0.5 2.6 1.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.9 3.2 3.2 1.6 1.2 1.8 0.9 0.9 0.9 0.9 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase, copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 18 "ASC diff: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 13 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Low region specificity" "Detected in many" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" 240000000 Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavourable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavourable (6.98e-4)" 97.0 11.5 0.4 18.7 1.0 0.0 67.7 0.5 1.3 26.9 44.3 1.0 16.3 3.6 44.7 34.8 36.1 18.5 50.9 12.1 0.4 0.4 5.8 8.3 48.0 7.9 0.5 1.2 23.8 2.4 2.2 1.3 10.8 2.0 36.5 9.4 32.1 8.0 24.7 7.7 5.5 15.0 79.2 0.6 7.5 17.7 16.2 0.3 1.0 6.6 11.6 2.6 75.9 20.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 83.5 0.1 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.2 0.3 1.4 0.1 0.1 4.6 0.2 0.0 0.2 0.9 0.2 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.2 0.7 0.0 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 1.2 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.5 1.3 0.4 0.4 0.5 1.2 2.0 0.3 AP000812.4 ENSG00000284844 11 72105924-72109329 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;cervix, uterine: 1.1;testis: 2.0" "Cell line enhanced" "Detected in some" "HSkMC: 1.4;RH-30: 1.2;SK-MEL-30: 2.9;WM-115: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" 0.0 0.0 0.0 1.1 0.0 0.9 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.2 0.5 0.4 0.0 0.0 0.0 0.9 0.5 0.2 0.1 0.4 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561100-47571920 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046188, HPA066326" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA046188: AB_2679578, HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 22.2 24.2 10.9 16.5 15.5 41.9 19.5 16.0 13.7 18.0 23.2 21.1 24.1 17.8 21.3 18.4 19.4 18.7 21.0 28.6 12.8 7.3 28.0 49.6 21.8 20.2 16.4 9.5 23.4 35.1 28.1 16.9 25.3 13.5 23.5 15.8 25.4 22.1 18.5 60.8 18.9 23.8 18.6 11.2 27.4 24.2 10.2 16.3 27.7 23.1 23.9 27.3 20.2 16.9 23.9 34.3 36.1 38.4 22.4 29.1 27.5 19.9 28.8 12.3 19.9 18.8 15.0 16.7 16.8 17.8 25.2 23.3 23.4 24.5 11.9 13.9 22.6 28.2 21.8 23.3 14.5 21.8 25.6 11.9 30.5 12.1 26.5 23.6 36.5 19.7 23.7 24.0 21.1 19.4 22.0 23.5 17.0 33.8 17.1 25.4 17.7 32.2 15.9 16.1 26.8 14.4 19.1 14.0 10.8 18.2 16.8 9.9 31.6 17.8 18.4 16.4 18.4 32.7 17.0 30.5 19.5 9.2 21.8 26.7 13.0 23.9 29.0 36.1 29.1 35.4 26.9 21.4 25.5 26.7 34.3 23.9 22.7 26.7 23.6 22.4 38.4 24.7 25.1 27.5 10.9 15.5 16.0 13.7 12.8 7.3 16.4 9.5 13.5 16.3 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869516-102901899 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 92.8;parathyroid gland: 30.0" "Cell line enhanced" "Detected in many" "AF22: 14.2;REH: 27.1;SH-SY5Y: 14.6;T-47d: 22.7" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 2.0 92.8 3.7 0.7 8.6 0.5 2.6 4.5 6.4 4.0 2.0 2.2 0.4 1.3 3.8 3.2 2.1 2.1 5.2 10.0 5.7 3.1 7.4 22.4 1.7 0.9 2.8 4.4 3.9 8.7 30.0 2.4 0.5 4.6 4.2 0.8 8.9 2.2 3.4 6.0 1.8 1.3 3.9 2.7 5.6 1.7 3.5 1.6 0.3 3.2 1.0 0.7 1.8 1.8 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 3.9 14.2 8.9 0.3 0.3 2.6 4.1 3.5 6.2 7.6 10.6 0.6 0.2 1.2 5.3 0.2 12.1 0.7 6.4 0.0 3.5 0.0 1.7 10.4 4.1 0.2 0.1 1.9 1.6 0.8 0.0 0.2 0.0 0.2 5.5 0.1 2.4 0.3 6.8 0.6 27.1 0.0 0.1 1.3 0.1 0.4 14.6 0.0 0.2 1.9 22.7 0.3 0.1 1.3 0.0 2.0 0.0 0.3 0.2 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.7 8.6 4.5 6.4 5.7 3.1 2.8 4.4 4.6 1.6 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" 900000 "Endoplasmic reticulum" "HPA055161: , HPA059303: " "unprognostic (8.07e-2)" "prognostic unfavourable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavourable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavourable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavourable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavourable (4.24e-4)" "unprognostic (2.74e-2)" 104.6 60.4 27.3 15.0 29.5 4.8 84.3 35.2 31.3 22.3 23.8 10.6 18.3 14.0 16.8 17.8 22.4 16.5 19.1 33.9 26.1 22.4 19.0 23.0 22.5 10.9 21.1 22.2 20.5 13.8 12.5 15.7 14.7 20.5 17.3 26.8 23.6 28.8 23.4 103.1 12.0 13.9 26.1 16.7 12.8 30.5 6.4 19.6 2.9 31.7 36.0 13.7 30.0 25.4 3.3 21.0 15.9 5.2 4.9 3.4 2.3 50.0 72.7 10.2 6.2 45.8 43.5 3.5 89.8 83.5 38.5 40.4 12.4 66.7 3.8 6.2 52.6 18.7 6.3 31.3 65.8 1.4 6.4 8.9 44.2 34.0 29.4 1.3 1.4 35.7 7.1 21.4 27.3 16.2 2.4 3.6 33.8 10.6 0.3 1.8 5.8 42.9 2.4 11.0 0.8 23.5 41.5 10.6 3.7 27.9 13.2 11.1 5.4 2.4 50.8 39.0 20.0 35.6 31.6 2.3 2.9 0.1 102.6 0.8 26.0 1.1 5.2 0.1 1.6 1.9 3.1 3.3 2.3 1.6 6.1 3.3 3.4 1.6 15.9 4.9 1.0 21.0 2.3 2.3 27.3 29.5 35.2 31.3 26.1 22.4 21.1 22.2 20.5 19.6 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740421-121928801 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm Nucleoplasm "HPA038444: AB_10672745, HPA057549: " "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favourable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 15.4 16.9 14.6 16.8 18.8 14.7 16.9 23.1 20.8 17.4 18.8 17.6 12.6 13.5 14.4 14.3 15.7 13.6 14.4 27.5 15.0 18.4 23.1 23.0 14.0 11.7 17.6 14.0 14.4 13.4 23.6 22.5 15.0 15.4 16.5 20.0 19.0 14.1 16.6 33.6 12.0 16.2 25.8 15.6 12.9 12.0 18.1 14.6 21.4 22.0 11.2 14.3 22.8 15.2 14.0 14.4 17.1 11.5 9.9 16.0 8.5 9.8 16.8 13.0 11.0 9.0 10.8 8.9 8.7 15.6 10.4 11.0 21.7 12.2 12.1 7.2 9.9 10.1 12.1 8.6 10.1 20.0 10.7 4.3 7.3 17.6 9.2 18.6 10.2 7.9 8.0 10.8 22.9 11.2 6.7 25.2 8.3 6.2 10.1 7.6 6.7 8.1 9.8 13.7 7.1 13.2 8.5 3.7 12.2 11.7 8.3 17.9 6.1 4.7 13.8 6.0 5.9 8.9 15.4 21.9 30.2 14.8 9.3 12.9 5.0 17.1 11.1 14.7 16.0 11.1 15.5 13.0 13.9 13.7 9.4 14.0 15.7 14.3 8.1 9.9 11.5 14.4 13.6 8.5 14.6 18.8 23.1 20.8 15.0 18.4 17.6 14.0 15.4 14.6 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB000102: , HPA067142: " "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.6 3.8 7.5 4.0 9.8 14.3 1.9 6.0 6.7 3.5 5.8 4.7 6.3 9.4 8.9 4.8 4.0 5.7 5.0 5.4 7.5 3.3 8.5 4.7 4.7 5.1 10.2 9.2 9.2 3.1 5.2 10.2 7.2 8.2 6.4 6.8 1.9 7.0 9.4 6.1 3.8 5.5 5.2 14.8 3.9 5.4 5.1 6.3 6.9 3.2 10.3 4.9 5.8 11.3 8.6 4.8 4.9 5.6 4.3 4.5 47.4 5.7 11.3 9.6 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavourable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.5 11.1 7.4 8.4 10.6 11.6 8.8 12.4 7.0 9.3 9.6 5.2 7.2 18.4 12.9 8.8 14.6 10.9 11.5 14.1 5.9 7.2 10.1 8.4 5.0 4.7 16.9 5.7 9.1 6.4 8.8 10.5 9.6 7.0 8.3 9.5 9.9 12.7 7.0 7.1 7.9 10.6 10.8 13.3 9.4 10.5 5.3 5.3 22.9 8.3 8.1 12.1 6.9 12.4 9.5 4.8 12.3 13.3 10.8 6.4 17.1 12.3 6.6 7.5 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361913 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favourable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 13.0 39.6 14.3 15.6 20.1 3.8 15.2 22.5 20.7 14.1 19.8 10.5 25.3 19.2 11.1 16.0 8.9 10.7 11.4 30.4 15.4 19.7 50.4 21.3 9.7 6.7 19.1 9.0 11.8 20.7 27.0 10.1 13.1 16.3 23.8 14.4 10.6 20.1 35.4 31.0 6.7 16.0 10.4 15.2 7.7 17.7 6.1 12.1 9.1 17.5 11.8 8.9 10.2 10.5 8.7 5.8 16.1 4.6 9.9 10.0 5.3 4.5 4.4 6.3 3.2 7.8 8.4 9.7 4.1 5.2 3.2 3.7 2.5 5.9 5.4 4.3 4.3 6.7 9.3 5.2 4.6 41.3 7.9 3.6 4.9 14.8 5.9 5.3 3.8 7.0 6.6 2.6 8.9 3.9 5.1 8.1 3.7 4.4 7.2 11.9 7.8 6.5 4.3 5.0 9.2 14.0 2.4 6.4 4.6 6.1 14.7 7.7 2.7 3.5 4.0 3.2 4.0 4.7 3.9 9.3 7.8 1.8 5.1 4.3 2.1 15.2 4.6 16.1 6.9 3.2 7.9 7.8 7.6 10.0 4.2 8.7 9.6 8.8 7.1 9.9 2.1 5.8 9.3 5.3 14.3 20.1 22.5 20.7 15.4 19.7 19.1 9.0 16.3 12.1 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavourable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavourable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 32.5 24.0 16.1 11.3 0.9 2.1 20.4 26.7 12.5 64.7 27.3 67.2 22.8 10.7 18.4 10.9 26.3 28.5 17.9 69.0 9.6 10.9 19.0 24.6 41.8 0.5 25.4 26.8 1.0 1.9 22.4 20.1 15.1 21.5 8.5 27.5 33.2 15.2 19.7 14.7 24.8 11.6 31.1 11.8 10.3 8.6 13.9 7.5 37.3 43.0 17.9 25.5 15.9 8.6 28.1 27.9 15.5 37.6 11.9 13.8 18.5 15.2 14.8 23.2 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Supported Nucleoplasm,Midbody "Nucleoplasm, Midbody" "CAB005862: AB_449204, HPA037708: " "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavourable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.0 28.2 42.0 20.2 0.9 1.4 16.1 19.7 10.6 40.8 37.7 36.5 12.4 41.0 10.2 7.8 30.2 30.5 13.5 33.8 18.0 50.1 24.4 16.1 30.8 0.1 12.9 24.0 0.7 0.6 23.9 15.0 18.8 15.2 15.9 17.9 19.5 46.8 18.3 26.1 12.6 31.7 38.7 17.0 8.9 8.1 9.1 13.0 17.5 7.9 13.4 13.8 8.7 7.3 16.4 16.9 14.7 51.2 11.6 7.7 30.8 7.9 19.6 33.1 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57230802-57235548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 72.0" "Cell line enriched" "Detected in some" 7 "NTERA-2: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034859 Uncertain "HPA034859: AB_10670298" "unprognostic (7.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.45e-2)" "unprognostic (8.07e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-5)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (6.46e-4)" 0.6 0.5 0.9 0.9 1.2 0.7 1.5 0.7 2.0 0.4 0.6 0.6 0.2 0.0 0.8 1.3 0.5 0.6 2.6 0.9 0.9 1.1 0.8 1.8 1.3 2.2 1.2 0.2 0.4 0.5 0.1 1.3 1.2 1.7 0.5 0.8 1.1 0.5 0.9 2.3 0.6 0.4 1.1 2.1 3.4 0.4 72.0 0.6 0.7 0.8 1.0 1.3 0.5 0.4 2.1 1.0 1.7 1.0 1.0 0.6 0.2 0.2 0.1 0.7 0.3 0.2 0.7 0.3 1.2 0.6 0.9 3.4 0.8 0.1 0.0 0.1 0.5 0.0 0.0 0.7 0.6 0.0 3.7 0.1 0.3 0.0 1.1 0.0 0.2 0.9 0.7 0.7 0.5 0.6 0.1 0.0 1.2 0.0 1.1 0.6 29.3 0.8 0.1 0.2 0.6 0.6 1.2 1.4 0.4 0.0 0.2 0.1 0.1 1.3 0.3 0.2 4.1 0.3 0.7 1.4 1.8 0.6 0.8 0.0 0.0 0.0 0.1 1.7 0.6 1.0 0.0 1.9 0.0 0.0 0.9 2.1 0.0 0.0 0.1 1.0 0.3 1.0 0.0 0.2 0.9 1.2 0.7 1.6 0.9 1.1 1.2 0.2 1.7 0.6 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: , HPA044864: " "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 4.4 1.9 3.2 11.8 4.8 16.1 4.9 1.2 5.8 7.3 5.4 5.4 3.6 3.7 6.8 5.0 10.0 4.1 3.9 3.6 3.4 2.8 2.2 2.1 5.3 8.2 5.1 1.9 5.8 3.7 3.6 6.3 3.8 4.5 5.7 6.1 1.9 4.7 6.5 12.4 16.3 4.5 7.5 5.3 4.7 3.8 9.5 3.9 25.8 4.0 8.0 9.9 8.3 7.8 9.7 6.6 6.0 3.4 6.1 16.0 2.0 7.7 4.3 11.7 6.0 1.6 2.0 8.0 9.4 5.5 9.3 10.7 5.4 7.7 8.3 4.5 3.9 8.5 8.4 5.5 13.3 6.6 4.4 8.3 7.9 5.7 0.6 9.2 8.4 2.7 0.8 8.2 4.5 3.1 4.6 23.5 8.9 6.4 16.5 9.6 9.2 2.2 14.3 11.8 7.5 2.7 6.5 3.7 5.9 8.6 9.9 3.4 10.2 9.2 2.7 12.0 8.4 7.0 8.5 7.1 7.9 16.9 4.8 7.0 8.0 2.9 1.7 6.0 4.8 3.4 3.1 8.9 5.3 5.2 3.0 9.7 2.5 3.6 0.5 6.1 2.9 6.6 16.0 2.0 3.2 4.8 1.2 5.8 3.4 2.8 5.1 1.9 4.5 3.9 BCKDK ENSG00000103507 "Branched chain ketoacid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 26.8;granulocytes: 26.6;monocytes: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria Mitochondria "HPA017995: AB_1845309, HPA056067: " "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 15.4 29.7 11.9 13.1 15.0 9.4 18.3 18.8 21.3 11.7 14.1 9.6 19.9 11.2 14.8 14.9 14.9 13.8 15.1 39.2 14.2 10.3 21.3 46.5 18.2 32.5 10.7 17.3 15.1 52.4 17.4 8.9 11.4 13.2 14.9 9.9 10.4 33.9 25.7 67.7 21.5 12.2 19.9 15.6 16.0 19.9 11.2 9.3 8.0 11.7 25.9 10.6 15.3 12.0 6.9 26.8 26.6 33.0 6.3 6.8 13.6 18.1 20.4 11.5 17.3 14.2 14.3 12.5 15.8 19.5 24.6 24.1 13.3 12.1 17.0 23.0 19.7 12.6 8.1 27.5 15.9 13.7 25.3 18.4 13.9 24.2 25.1 9.5 16.9 21.0 11.1 21.1 17.6 26.2 9.3 16.1 36.8 30.9 8.8 12.6 9.8 16.5 17.8 16.8 31.3 18.8 12.5 17.8 16.3 12.3 30.3 9.8 18.2 9.2 16.8 18.8 10.9 19.2 13.1 16.8 6.0 6.0 21.3 13.8 17.6 12.2 33.0 23.1 5.7 27.4 5.6 6.9 5.2 4.2 26.8 5.4 4.4 5.0 26.6 6.3 19.3 5.8 6.8 13.6 11.9 15.0 18.8 21.3 14.2 10.3 10.7 17.3 13.2 9.3 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR, RhoGEF and GTPase activating protein" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favourable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 14.5 8.4 24.0 9.1 41.2 26.7 10.5 14.2 26.5 13.6 9.7 10.3 10.6 8.7 9.2 13.9 19.3 10.8 8.3 7.8 20.9 13.0 16.3 8.3 11.3 10.9 16.0 15.6 8.8 12.9 14.5 14.9 15.7 14.2 7.0 6.8 8.3 15.5 9.7 3.4 12.8 8.7 9.0 9.5 9.1 14.0 9.6 15.4 11.8 16.6 5.5 9.2 9.2 8.8 1.5 0.8 1.2 1.0 2.8 6.6 2.5 18.6 8.1 12.4 12.7 7.4 5.1 18.8 6.8 6.3 6.3 5.1 14.1 7.5 13.0 12.6 5.7 19.2 1.3 18.8 1.8 24.9 12.9 11.4 11.1 11.2 9.7 10.5 6.0 4.3 12.7 9.4 8.2 21.8 43.5 6.1 2.8 12.3 9.8 8.2 10.5 7.9 12.9 5.0 8.6 9.7 11.8 11.4 10.8 12.4 10.7 5.1 6.7 8.6 24.6 3.8 0.4 6.1 5.5 1.4 5.6 4.6 9.7 8.0 5.8 0.0 1.0 0.0 6.6 0.4 2.3 1.4 3.3 3.3 0.8 1.5 2.6 3.6 1.2 2.8 1.0 0.8 1.6 2.5 24.0 41.2 14.2 24.9 20.9 13.0 16.0 15.6 14.2 15.4 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Supported "Golgi apparatus,Vesicles,Mitotic spindle" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: " "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 15.0 16.7 10.3 20.7 14.4 18.4 16.1 21.9 13.7 16.2 13.0 15.3 15.6 8.7 17.2 13.9 13.2 13.1 11.7 11.4 9.8 7.3 14.1 14.8 12.5 16.1 13.9 11.8 23.6 24.8 32.5 17.4 14.1 14.8 11.3 13.6 11.5 14.7 17.1 20.9 14.9 16.0 12.5 13.3 16.1 13.9 13.0 14.4 23.1 21.5 9.2 17.2 16.2 12.0 3.8 2.8 10.6 2.4 2.3 3.4 0.7 15.1 12.7 11.8 5.1 9.3 13.2 7.1 6.7 9.5 8.3 7.9 8.7 3.6 16.3 5.4 12.6 7.0 16.5 10.0 10.3 13.0 7.5 22.0 8.0 7.2 5.1 20.4 7.8 8.8 4.9 13.0 11.6 12.3 17.8 7.0 7.7 5.8 10.2 4.7 7.9 7.5 10.4 19.0 5.5 6.0 15.6 8.8 13.5 13.3 6.9 6.1 4.6 7.3 19.2 8.7 9.8 5.9 10.2 9.4 13.1 21.8 6.3 10.1 5.7 10.6 1.6 0.9 2.7 1.2 3.4 1.7 2.1 2.3 1.3 3.8 2.3 2.6 2.7 2.3 2.4 2.8 1.6 0.7 10.3 14.4 21.9 13.7 9.8 7.3 13.9 11.8 14.8 14.4 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916372 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 37.9;HMC-1: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favourable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 11.4 11.1 15.6 18.6 15.0 15.3 12.0 8.2 12.7 11.1 13.9 20.3 2.1 8.0 11.3 9.6 15.7 10.0 12.3 17.0 18.0 9.5 8.3 10.2 14.1 22.9 20.9 12.0 6.5 6.4 7.7 7.8 14.4 14.5 8.4 18.9 11.4 10.2 6.0 7.5 14.5 15.9 10.4 28.3 19.2 7.4 19.6 16.5 19.9 12.5 5.9 24.4 9.7 12.8 2.7 1.7 3.8 2.6 0.4 0.4 0.5 5.4 2.0 3.0 3.9 5.9 5.6 2.3 5.2 8.1 5.9 7.7 3.7 2.9 6.6 2.7 25.2 1.3 3.5 4.2 10.8 1.8 1.2 37.9 2.4 1.7 6.5 7.9 41.1 8.2 5.5 9.2 8.5 7.9 10.2 19.0 6.9 1.1 4.7 3.3 1.4 1.3 6.8 5.4 1.6 7.2 2.9 4.7 2.5 7.6 3.9 4.6 1.4 4.1 7.7 5.8 2.3 9.6 5.6 3.5 1.4 2.5 5.1 9.9 4.0 0.4 2.2 1.2 0.1 0.9 0.1 2.7 0.1 0.0 1.7 2.7 0.4 0.2 3.8 0.4 2.6 1.3 0.0 0.5 15.6 15.0 8.2 12.7 18.0 9.5 20.9 12.0 14.5 16.5 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932838 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavourable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 8.9 7.0 9.4 7.9 12.4 0.9 10.7 14.1 9.2 19.4 20.6 10.9 7.7 6.2 16.3 12.3 8.4 10.9 10.8 11.0 7.7 6.1 8.2 4.6 7.4 2.9 7.3 7.6 16.1 10.6 10.0 14.0 7.4 8.5 12.8 9.3 10.9 12.6 14.2 8.4 11.3 9.8 16.5 12.2 3.4 12.1 7.8 9.2 0.3 19.4 7.8 5.7 16.0 11.4 1.8 1.1 3.6 0.8 0.9 1.4 0.3 7.5 3.8 14.7 12.5 7.7 5.0 2.6 7.6 8.0 4.5 5.2 6.5 6.7 2.3 3.5 9.7 8.1 6.5 8.3 6.6 2.5 3.7 2.9 3.6 10.7 4.1 4.0 20.4 4.4 3.5 6.0 4.4 0.0 4.5 1.6 5.2 3.2 2.6 3.2 8.0 1.8 0.0 5.8 0.0 9.2 7.2 1.5 4.8 8.5 4.3 5.1 7.3 2.0 3.8 3.2 5.2 6.6 7.0 0.4 7.0 2.9 2.8 2.7 2.6 2.0 0.8 0.6 1.4 0.5 0.9 1.8 1.4 1.2 0.3 1.5 1.0 1.1 3.6 0.9 0.6 1.1 0.7 0.3 9.4 12.4 14.1 9.2 7.7 6.1 7.3 7.6 8.5 9.2 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757968-95158448 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 28.0;ductus deferens: 25.1;prostate: 25.3;seminal vesicle: 32.0" "Cell line enhanced" "Detected in many" "A549: 18.3;MCF7: 9.2;SH-SY5Y: 15.3" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favourable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 1.1 5.6 12.7 0.8 15.0 0.7 1.7 11.6 12.7 28.0 1.2 5.5 25.1 0.7 5.3 3.2 1.1 14.3 3.4 1.3 13.4 5.9 9.3 1.4 2.4 0.5 5.4 8.6 7.6 1.7 0.6 2.4 1.2 12.1 25.3 0.8 0.7 1.4 32.0 3.3 1.4 0.6 1.2 7.5 1.4 2.8 4.3 11.2 10.8 0.8 0.1 0.6 0.7 0.7 0.4 0.5 1.9 0.9 0.8 1.6 0.3 0.0 18.3 4.9 0.0 1.9 4.5 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.8 1.0 2.9 6.7 0.0 0.0 4.5 0.0 1.1 0.0 0.5 0.4 0.0 2.8 7.5 2.8 5.6 0.0 0.0 0.0 7.0 9.2 0.6 0.1 1.8 3.1 0.1 2.7 0.1 3.5 0.1 0.2 15.3 0.2 2.5 2.5 1.9 0.0 0.0 3.9 3.1 0.1 3.3 0.0 0.0 0.0 1.5 0.0 0.4 1.9 0.3 0.5 0.4 0.5 0.7 0.4 0.6 0.3 0.3 0.3 0.5 0.5 0.8 0.8 0.9 0.5 1.6 0.3 12.7 15.0 11.6 11.8 13.4 5.9 5.4 8.6 12.1 11.2 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376936-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA017385: AB_1845397, HPA049014: " "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.1 15.0 12.1 9.8 14.2 1.1 10.2 9.5 17.1 15.7 11.7 8.2 6.5 5.5 12.9 10.2 10.6 10.3 13.2 14.6 10.8 13.5 10.7 11.5 24.9 4.4 10.4 14.5 12.0 7.0 15.5 6.1 21.7 10.8 11.0 7.7 11.4 7.1 9.1 10.6 7.2 8.1 15.3 7.5 8.9 7.2 12.9 3.8 3.9 11.6 5.2 5.4 11.1 8.9 1.6 2.6 0.9 2.7 1.1 3.6 0.9 5.7 5.4 5.5 8.7 13.9 13.4 10.7 11.9 12.0 10.4 10.4 4.7 8.7 2.0 13.9 24.0 10.8 7.2 9.2 16.3 5.9 4.9 6.0 5.7 7.3 9.6 1.7 4.7 9.8 8.7 7.6 10.2 30.0 3.9 9.9 12.8 10.7 1.4 1.5 3.0 4.9 3.9 10.9 3.0 8.9 12.2 5.6 5.6 12.6 7.6 14.0 5.8 4.0 33.0 21.2 11.3 7.2 7.2 1.4 1.7 0.6 5.1 3.8 6.1 0.5 2.0 0.9 3.4 1.8 2.5 1.5 1.3 2.2 2.3 1.6 2.7 1.4 0.6 1.1 2.7 2.6 3.6 0.9 12.1 14.2 9.5 17.1 10.8 13.5 10.4 14.5 10.8 3.8 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: " "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.4 4.6 6.8 8.1 8.3 10.7 10.9 6.1 6.5 4.9 7.1 5.0 5.9 9.3 4.7 6.2 3.0 6.0 4.8 9.0 8.6 4.9 6.0 4.5 4.6 7.0 9.8 6.1 7.1 5.4 5.2 10.8 5.7 9.5 16.7 8.7 2.9 13.0 10.3 6.3 2.9 8.5 5.8 7.6 4.8 10.4 7.9 6.6 7.0 4.3 6.3 4.0 6.7 8.4 5.3 4.1 11.5 4.9 19.4 11.0 14.8 8.7 9.9 5.7 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685986 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" Cytosol "Nuclear membrane" "HPA040357: AB_10967924, HPA058820: " "unprognostic (7.02e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "prognostic unfavourable (7.65e-6)" "unprognostic (2.14e-1)" "unprognostic (9.24e-3)" "unprognostic (2.80e-1)" "unprognostic (1.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (3.66e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-2)" "unprognostic (8.08e-2)" 9.8 9.9 9.8 7.2 11.6 26.5 9.6 10.0 12.8 8.3 9.3 10.0 8.0 8.6 10.1 7.0 9.4 8.4 7.3 8.8 8.6 8.7 8.4 9.3 7.9 9.7 9.2 8.5 9.7 7.8 9.4 10.4 9.8 12.0 8.3 9.0 6.7 8.9 9.7 19.1 12.7 9.3 9.1 11.1 9.6 7.9 55.9 10.1 12.4 9.5 5.6 10.4 10.2 11.8 12.7 11.7 25.7 13.5 16.6 18.5 11.6 9.7 14.4 11.8 13.5 12.6 10.7 19.7 13.7 11.6 16.0 12.3 19.3 6.8 18.8 8.2 13.0 12.0 16.4 11.2 17.1 12.0 10.6 23.3 9.0 13.0 15.9 20.4 15.8 12.0 16.0 13.8 22.4 13.8 24.1 6.2 13.1 12.3 16.9 19.7 15.9 15.2 15.8 12.9 16.8 10.5 20.6 14.7 10.9 16.1 13.7 13.4 15.0 13.0 12.7 10.3 9.6 9.2 9.7 15.9 20.0 20.8 9.7 11.3 11.2 16.1 13.0 24.0 14.7 13.5 14.3 12.7 15.4 14.7 11.7 12.5 14.6 14.8 25.7 16.6 10.6 8.4 18.5 11.6 9.8 11.6 10.0 12.8 8.6 8.7 9.2 8.5 12.0 10.1 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748018 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavourable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavourable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 10.5 7.7 6.2 10.4 8.1 29.2 10.7 16.5 13.1 10.7 9.5 10.4 5.0 6.8 14.4 8.9 10.7 12.9 10.7 7.0 5.4 4.2 8.2 5.3 10.7 12.3 8.3 7.0 12.5 9.2 11.3 9.5 9.9 7.5 9.0 6.3 9.6 12.1 8.5 11.1 14.2 10.5 8.3 5.1 12.2 9.2 23.7 11.4 24.3 12.0 7.8 11.4 11.5 9.4 1.2 3.5 2.3 1.8 9.3 4.2 1.3 5.3 8.3 8.3 4.0 5.2 4.4 42.4 6.6 4.4 7.8 5.8 7.4 4.6 9.2 3.1 6.6 4.5 8.4 6.7 5.6 9.7 8.9 11.9 16.6 4.9 6.1 16.9 11.1 5.6 5.6 11.5 6.9 6.0 12.6 9.3 4.9 12.9 10.5 13.9 10.5 7.8 14.2 5.8 6.4 4.1 8.5 4.9 7.6 7.1 5.2 6.0 5.2 16.4 7.6 9.2 7.8 7.9 12.1 7.5 8.4 17.1 7.2 13.9 7.9 2.2 1.8 2.3 2.7 1.6 4.2 1.1 2.1 2.5 1.5 1.2 2.5 2.9 1.3 9.3 1.5 3.5 1.3 1.3 6.2 8.1 16.5 13.1 5.4 4.2 8.3 7.0 7.5 11.4 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 25.9;SH-SY5Y: 23.2;WM-115: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported Nucleoplasm Nucleoplasm "HPA021212: AB_1845455, HPA061719: " "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favourable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavourable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.2 15.3 8.0 0.0 0.6 0.1 2.4 3.4 3.3 4.8 5.9 2.7 3.1 1.7 2.7 0.1 3.2 0.1 3.1 14.4 12.6 2.0 1.6 0.6 3.3 0.6 5.9 2.1 0.3 3.3 0.0 0.1 2.8 18.8 2.9 0.8 3.6 0.7 11.1 1.0 8.3 3.8 0.5 0.2 0.0 25.9 23.2 0.0 0.4 5.6 1.3 1.7 0.0 6.3 6.7 3.5 4.6 15.6 11.4 7.0 6.5 1.4 21.1 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Cell line enhanced" "Detected in some" "AF22: 8.9;AN3-CA: 9.7;CACO-2: 7.7;HAP1: 7.2;NTERA-2: 15.0;SCLC-21H: 35.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.9 8.9 9.7 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.7 0.5 0.0 1.3 0.1 0.0 7.2 0.0 0.6 0.9 3.8 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.9 0.0 0.0 15.0 1.2 0.0 0.0 0.0 0.1 0.1 35.0 5.2 1.7 0.1 2.4 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637698-110678114 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 56.5;testis: 30.9" "Cell line enhanced" "Detected in many" "HEL: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavourable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavourable (1.03e-5)" "prognostic unfavourable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavourable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 1.1 0.9 0.5 15.8 1.0 8.9 0.6 0.3 1.0 1.2 2.8 0.4 0.0 2.4 0.7 2.3 5.8 0.5 1.0 1.1 0.5 0.5 0.9 0.8 2.1 11.6 0.6 0.2 1.0 0.7 0.0 0.4 2.4 0.5 0.7 4.3 0.4 1.4 0.0 0.5 1.8 3.1 1.4 1.3 7.9 1.8 30.9 0.1 56.5 0.6 5.7 12.1 2.5 2.0 1.8 2.4 3.0 0.2 1.4 6.1 1.1 29.9 8.8 23.1 14.5 1.0 1.7 12.3 15.6 10.3 27.2 20.5 18.4 17.2 20.3 9.7 9.0 13.1 29.5 11.3 33.8 16.1 14.4 67.2 9.4 14.7 0.2 19.3 19.0 0.4 0.7 20.9 10.4 15.8 29.4 42.4 22.2 9.8 32.3 16.2 22.3 16.6 21.5 19.8 31.0 5.5 9.5 15.5 6.7 11.1 9.4 8.4 7.4 16.4 6.5 12.4 20.2 9.3 21.6 22.2 20.8 25.0 8.3 15.0 21.7 3.0 0.0 0.7 0.6 0.2 0.9 1.8 2.5 1.0 0.8 1.4 1.6 1.5 0.0 1.4 0.1 2.4 6.1 1.1 0.5 1.0 0.3 1.0 0.5 0.5 0.6 0.2 0.5 0.1 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008419 Supported Cytosol Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (7.43e-6)" "prognostic unfavourable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.6 11.0 35.1 13.9 0.8 2.5 11.3 20.5 11.5 22.0 19.1 16.0 8.3 19.6 11.5 7.4 24.4 33.1 11.1 24.0 16.8 17.8 28.6 28.4 14.9 0.0 25.7 15.7 0.5 0.6 13.4 12.7 15.9 24.6 20.9 21.9 7.3 20.2 15.7 23.7 12.5 21.7 28.8 14.8 6.7 11.0 22.9 14.1 12.7 12.1 4.5 14.1 13.4 9.2 16.9 17.9 16.8 18.2 10.9 18.5 32.0 9.0 29.0 21.9 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 CALM1 "CALML2, CAMI, DD132, PHKD" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408261 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 176.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB018558, HPA044999" Supported Approved Vesicles Vesicles "CAB018558: AB_2069454, HPA044999: " "unprognostic (5.35e-3)" "unprognostic (3.96e-1)" "unprognostic (4.99e-3)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.52e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" "prognostic favourable (5.62e-4)" "unprognostic (2.77e-1)" "prognostic favourable (6.49e-4)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-2)" "prognostic unfavourable (2.38e-5)" 47.5 28.1 141.5 26.9 148.2 57.2 21.5 149.6 176.0 27.4 55.9 49.4 20.7 53.9 20.3 41.7 58.8 48.6 29.5 52.3 139.8 86.1 61.5 39.0 38.7 27.8 85.2 100.1 20.9 22.6 41.4 27.6 38.6 106.1 33.7 60.5 22.2 33.2 43.5 100.2 19.3 50.6 42.6 71.1 29.3 35.6 22.3 49.8 12.6 22.7 18.8 37.8 32.7 21.8 45.7 42.8 90.3 53.7 88.8 118.3 109.4 27.0 37.7 45.0 17.3 50.6 44.6 38.4 49.9 42.8 38.6 41.9 40.1 48.0 29.3 26.0 58.8 45.3 28.1 69.3 64.3 56.9 18.0 30.9 32.4 36.7 27.7 46.9 25.0 28.0 34.7 37.8 13.4 86.9 14.3 40.2 52.8 91.9 15.5 45.9 26.1 52.7 31.0 40.2 19.7 31.9 83.4 94.2 39.6 43.6 76.4 27.8 50.5 16.4 53.9 32.6 20.9 34.1 41.5 22.4 50.7 32.1 51.5 39.4 45.2 90.3 31.8 71.0 96.0 37.9 118.3 45.7 102.5 101.0 42.8 35.7 74.8 88.1 47.0 88.8 53.7 40.5 105.6 109.4 141.5 148.2 149.6 176.0 139.8 86.1 85.2 100.1 106.1 49.8 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160082-47176601 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB007790, HPA044999" Approved "CAB007790: AB_562257, HPA044999: " "prognostic unfavourable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavourable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favourable (1.94e-5)" "unprognostic (1.24e-1)" 65.6 87.3 153.0 41.3 162.1 25.3 89.8 132.9 169.5 58.4 88.7 62.8 38.8 68.4 60.1 73.8 50.8 71.6 51.3 55.0 160.4 133.1 57.9 62.0 63.9 48.4 135.8 147.6 57.5 28.1 37.7 51.2 59.3 119.6 60.4 92.3 29.3 60.4 77.7 30.2 31.0 77.7 81.7 139.9 77.3 50.0 79.1 114.9 43.8 60.0 31.0 57.1 56.5 37.1 53.2 82.3 190.9 141.0 38.4 40.3 130.5 169.8 65.4 75.6 33.5 43.1 48.9 48.5 168.3 104.3 100.3 86.5 64.3 63.9 72.3 76.5 122.4 44.2 64.1 59.3 132.2 55.4 30.3 61.7 39.4 93.4 55.6 74.8 48.8 27.9 57.8 89.4 101.4 67.2 57.7 59.6 239.3 44.5 87.2 64.5 58.7 33.4 21.8 89.3 68.3 112.5 31.2 55.5 141.4 54.3 53.9 73.1 40.1 40.0 77.5 74.8 82.9 44.8 117.8 47.4 41.4 77.0 50.8 51.8 95.9 140.3 98.3 190.9 29.8 141.0 32.3 53.2 37.2 35.8 82.3 36.9 33.2 36.4 102.4 38.4 122.1 78.5 40.3 130.5 153.0 162.1 132.9 169.5 160.4 133.1 135.8 147.6 119.6 114.9 CALM3 PHKD ENSG00000160014 "Calmodulin 3" P0DP25 19 46601074-46610793 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 181.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA044999 Approved "HPA044999: " "unprognostic (3.39e-1)" "unprognostic (1.30e-1)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" "unprognostic (9.81e-2)" "unprognostic (1.29e-2)" "unprognostic (2.39e-2)" "prognostic unfavourable (2.07e-4)" "unprognostic (4.01e-3)" "unprognostic (5.28e-2)" "unprognostic (1.67e-1)" "unprognostic (5.34e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" "unprognostic (1.07e-1)" "prognostic favourable (9.10e-4)" "unprognostic (2.72e-1)" 23.0 29.0 113.3 27.0 142.8 30.5 15.6 76.6 181.1 27.4 31.6 21.5 8.2 37.4 24.5 18.8 22.5 25.9 25.2 47.5 120.2 75.6 23.4 25.3 19.3 29.7 70.1 110.8 37.4 19.3 16.5 16.0 24.5 90.5 25.6 30.0 17.8 12.4 31.6 52.7 15.3 41.7 31.3 34.7 18.5 22.8 44.7 20.5 27.1 22.3 8.6 30.6 28.5 17.4 13.0 17.4 82.2 34.2 18.8 35.3 26.8 52.7 62.2 73.3 25.8 38.8 52.0 15.8 54.1 49.6 53.3 71.3 52.5 51.2 45.1 22.7 86.7 37.3 72.8 47.0 68.0 55.0 47.1 61.8 30.4 60.0 21.0 49.0 84.7 50.8 16.0 41.3 33.2 66.0 45.5 67.8 50.5 36.1 47.3 109.8 34.3 24.5 83.4 39.0 17.1 50.5 66.6 37.2 39.6 44.0 29.6 17.2 34.3 53.1 47.2 28.9 50.3 22.1 42.1 42.6 34.3 36.7 29.4 39.9 37.9 28.5 30.2 46.3 13.0 34.2 11.7 13.0 18.7 17.4 17.4 11.5 21.7 14.0 82.2 18.8 33.2 10.4 35.3 26.8 113.3 142.8 76.6 181.1 120.2 75.6 70.1 110.8 90.5 20.5 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol 550000 Cytosol "CAB031904: AB_630964, HPA051409: " "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavourable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.6 2.9 0.0 15.1 5.6 7.3 8.6 4.8 9.9 9.4 5.3 0.6 0.2 2.0 5.8 0.6 0.0 1.1 6.2 0.1 21.1 11.6 6.9 7.4 8.4 1.0 92.0 5.9 0.9 13.9 1.5 8.3 1.5 0.2 3.7 2.2 0.0 8.5 2.0 5.7 0.0 0.1 0.2 5.9 0.6 0.9 3.7 1.5 0.1 0.8 0.9 14.9 4.3 4.5 5.6 6.4 10.8 0.0 0.0 0.2 9.6 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.7;U-266/70: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favourable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.5 2.9 0.1 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.5 2.0 1.4 0.3 0.2 1.3 3.5 0.5 0.5 46.7 1.8 5.6 8.3 0.2 0.5 0.1 5.1 0.1 2.3 1.2 0.1 0.3 0.1 0.2 0.7 2.9 10.9 2.2 1.9 1.1 8.3 1.6 2.6 0.1 2.7 4.5 2.0 5.5 2.0 0.0 1.5 1.3 0.1 2.4 3.6 7.7 1.6 21.5 6.7 4.7 3.6 3.6 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583717-209613938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 34.4;ovary: 29.2" "Cell line enhanced" "Detected in some" "BJ: 2.0;hTEC/SVTERT24-B: 12.1;NTERA-2: 1.9;SK-MEL-30: 3.6;U-138 MG: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.17e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.49e-3)" "unprognostic (2.56e-2)" "unprognostic (1.93e-1)" "unprognostic (6.79e-2)" "unprognostic (3.98e-1)" "unprognostic (3.59e-3)" "unprognostic (8.55e-3)" "unprognostic (3.17e-2)" "unprognostic (1.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.27e-1)" "unprognostic (9.10e-2)" "unprognostic (3.43e-2)" 0.7 3.5 7.5 0.9 34.4 1.0 0.7 1.3 27.8 1.1 0.8 0.7 1.2 0.8 1.8 6.1 0.6 0.9 1.5 0.6 10.9 9.2 6.9 0.9 1.2 0.8 3.6 17.7 29.2 1.3 0.6 2.0 2.8 3.9 4.6 0.8 0.6 0.6 7.4 0.6 0.6 0.8 2.3 0.9 6.1 0.7 1.4 2.7 0.0 0.7 0.0 0.8 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.0 0.3 0.8 0.3 0.0 0.2 0.0 0.0 0.8 0.2 0.0 0.0 1.3 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 12.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.2 2.1 0.2 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 34.4 1.3 27.8 10.9 9.2 3.6 17.7 3.9 2.7 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;SCLC-21H: 9.5;U-87 MG: 8.0" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: , HPA051785: , HPA053973: " "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 2.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.0 9.5 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.8 0.2 0.1 0.2 0.7 0.0 1.0 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 5.2 0.0 0.2 0.1 2.3 0.1 0.9 0.1 0.0 0.0 41.0 2.2 0.2 0.0 0.0 1.9 0.1 0.2 0.2 0.3 0.2 0.0 0.5 0.4 0.1 0.1 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: , HPA051785: , HPA053973: " "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.3 15.8 5.3 34.6 66.2 5.6 33.5 22.4 13.2 11.4 9.6 4.0 20.5 4.9 23.3 0.5 9.8 5.2 13.5 7.8 2.5 0.0 5.2 11.0 17.5 0.0 0.0 42.3 7.2 10.2 25.3 11.7 0.8 9.2 24.8 3.8 2.0 0.8 2.2 5.3 4.0 18.5 0.1 13.5 9.7 4.3 4.3 4.5 6.8 4.5 0.1 5.5 7.0 34.9 8.2 14.8 6.6 7.1 3.6 17.6 18.0 1.2 16.4 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell line enhanced" "Detected in all" "PC-3: 45.4;SK-BR-3: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 10.9 7.9 7.1 13.6 5.2 8.6 8.4 7.5 12.9 10.4 8.5 12.2 11.8 8.1 7.9 9.7 17.0 5.6 6.4 8.3 7.3 6.7 5.5 6.1 5.5 2.6 7.5 9.3 4.5 5.8 10.3 7.2 8.8 6.0 12.1 5.7 7.6 12.5 11.2 5.2 45.4 11.4 7.5 4.3 5.4 15.9 3.7 8.6 4.3 57.2 3.7 10.7 4.7 10.8 7.7 12.4 4.2 10.1 3.7 4.4 7.5 8.3 21.5 2.7 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.2;MOLT-4: 12.6;SH-SY5Y: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 1.0 0.3 1.1 0.0 0.3 3.2 3.8 3.7 0.0 0.0 0.0 2.0 0.1 0.1 3.1 0.3 2.8 41.2 2.6 0.6 1.3 0.0 0.1 0.2 0.1 0.1 0.0 8.0 0.8 0.6 0.0 1.5 0.2 0.0 12.6 0.0 1.9 0.1 1.9 2.4 0.1 1.4 0.0 9.1 16.1 0.5 0.0 2.7 0.0 0.2 0.0 7.8 4.6 0.0 6.9 1.3 0.1 0.0 3.8 0.0 3.0 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.9;salivary gland: 27.1" "Cell line enhanced" "Detected in many" "HeLa: 17.8;U-87 MG: 20.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favourable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 4.3 10.2 15.3 5.1 21.4 3.7 4.7 23.2 38.9 4.1 3.2 2.2 4.0 3.1 7.5 5.2 4.2 3.7 3.8 5.7 13.8 6.8 1.5 1.0 4.0 2.5 5.5 16.0 6.0 7.5 5.0 10.1 2.3 11.2 3.3 3.1 2.5 27.1 11.2 2.2 7.8 3.7 6.2 2.2 4.3 2.9 6.1 5.0 1.7 7.2 2.3 2.5 5.6 4.9 0.1 1.6 5.6 4.1 0.0 1.0 1.1 4.8 8.4 0.9 4.2 3.0 5.4 0.3 3.4 3.7 3.2 1.5 3.0 1.5 2.9 3.6 6.4 14.5 2.3 4.1 2.0 0.1 7.7 3.3 17.8 1.1 3.1 0.5 2.6 4.1 3.5 6.1 2.1 1.4 2.6 0.1 1.6 1.3 4.0 1.9 0.9 7.9 2.1 3.7 3.4 3.5 3.1 4.9 2.7 1.3 10.0 2.2 3.8 1.1 2.0 5.6 7.6 7.1 2.7 0.4 0.2 0.1 20.5 2.8 0.7 0.0 1.8 3.6 0.6 3.9 1.0 0.0 0.6 0.5 1.6 0.1 0.6 0.3 5.6 0.0 4.1 0.8 0.0 1.1 15.3 21.4 23.2 38.9 13.8 6.8 5.5 16.0 11.2 5.0 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237691-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 125.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 125.5" "Group enriched" "Detected in many" 5 "classical monocyte: 14.2;eosinophil: 26.1;intermediate monocyte: 19.4;myeloid DC: 7.2;neutrophil: 17.2;non-classical monocyte: 16.5" "Group enriched" "Detected in all" 5 "dendritic cells: 7.2;granulocytes: 26.1;monocytes: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 11.7 6.5 19.7 7.8 30.2 13.8 8.8 125.5 45.5 9.0 9.5 7.1 2.6 12.8 8.6 5.3 8.3 11.8 6.3 6.9 11.2 5.1 7.1 8.9 9.6 6.9 6.2 17.3 10.5 5.8 6.4 4.1 7.5 9.1 12.2 9.7 6.2 7.5 13.2 5.1 9.1 13.2 10.3 6.2 14.1 7.6 3.6 5.8 5.2 6.1 4.5 7.2 7.2 7.4 2.2 7.2 26.1 19.4 3.6 2.2 6.3 12.3 9.3 6.9 13.4 20.8 19.4 10.6 10.2 10.9 8.4 7.7 9.7 5.3 19.1 8.6 20.7 10.2 8.5 11.0 6.6 13.1 16.7 9.5 6.2 9.5 14.1 21.6 9.1 12.5 16.4 7.9 18.0 19.6 11.0 10.4 8.1 12.0 23.9 17.8 5.0 10.5 15.6 8.0 16.9 8.1 13.8 26.6 10.6 13.4 7.2 8.5 17.9 26.4 14.3 6.9 5.6 5.8 5.6 39.7 23.6 14.5 12.9 15.1 6.8 0.7 14.2 26.1 2.1 19.4 2.2 2.2 1.7 1.9 7.2 1.2 1.5 1.7 17.2 3.6 16.5 1.6 1.3 6.3 19.7 30.2 125.5 45.5 11.2 5.1 6.2 17.3 9.1 5.8 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871513-10923070 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 64.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073" Supported Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "CAB032961: AB_2068446, HPA043561: , HPA048073: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (8.37e-4)" 12.2 8.8 12.3 12.6 16.1 13.2 9.6 12.5 17.7 15.8 14.0 9.3 9.0 11.5 19.6 9.1 20.5 14.8 12.4 14.7 11.2 7.2 9.3 14.5 8.9 12.4 7.8 10.2 13.0 16.9 8.2 6.9 15.3 9.5 12.6 10.2 12.0 11.4 13.2 64.3 12.5 12.0 15.6 6.6 9.8 11.1 17.5 8.6 9.4 10.0 12.7 15.6 15.8 15.9 1.3 1.6 0.3 1.4 0.1 2.6 0.4 22.4 16.7 24.1 32.6 20.1 27.5 23.1 16.2 28.1 24.1 23.2 25.8 8.3 31.0 19.4 28.2 21.5 24.5 24.3 15.2 34.7 20.0 9.5 10.9 31.3 17.2 14.3 12.4 18.8 15.9 16.4 19.8 30.4 22.8 27.9 14.1 40.7 24.9 12.3 29.7 27.9 34.9 12.3 36.0 14.5 11.7 17.5 16.8 11.6 14.0 15.6 14.0 12.3 18.2 29.0 16.4 27.5 18.9 27.2 21.4 27.1 19.1 23.0 12.6 0.0 1.4 0.2 1.2 1.4 0.5 1.3 0.9 2.6 1.3 1.3 1.0 0.9 0.3 0.1 0.7 1.6 0.8 0.4 12.3 16.1 12.5 17.7 11.2 7.2 7.8 10.2 9.5 8.6 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.8 13.9 13.3 7.9 9.0 7.4 4.3 9.5 7.9 5.6 5.1 29.9 17.7 0.1 4.9 11.8 21.8 14.7 9.7 9.4 9.6 8.2 0.0 12.5 10.6 9.3 1.7 1.4 8.4 26.7 10.6 13.6 4.5 0.8 8.5 12.1 12.7 3.1 0.7 12.2 9.1 5.1 32.8 5.2 12.6 23.7 12.2 6.5 17.9 7.1 5.4 7.7 0.3 5.3 10.5 10.6 8.9 5.2 3.3 2.0 3.6 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206276-119313926 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 9.9 5.5 9.1 17.0 11.1 11.1 8.8 10.7 12.0 6.2 7.5 8.7 3.0 5.7 9.9 5.3 7.5 7.4 6.3 5.9 8.0 9.6 5.5 4.0 10.3 16.3 8.1 6.9 6.3 5.6 16.6 4.1 9.1 9.3 5.3 7.5 6.4 5.4 7.1 3.9 7.4 8.6 10.6 8.9 13.3 7.3 32.3 5.1 40.9 6.0 5.5 15.6 7.6 7.7 1.8 3.3 11.8 3.7 0.6 1.9 1.0 6.3 4.8 16.8 10.5 5.0 6.0 9.9 6.8 7.1 6.6 6.6 10.2 7.8 15.0 6.2 8.6 9.3 11.5 5.8 14.5 8.5 2.7 15.4 3.6 3.1 6.2 17.9 17.6 5.2 6.5 16.9 18.2 16.3 12.4 6.3 11.9 6.8 9.5 10.0 8.7 5.3 10.3 8.4 2.8 5.9 5.1 2.3 7.0 12.7 5.5 4.5 5.8 15.1 13.6 10.3 7.3 7.2 8.9 2.1 3.1 12.2 4.2 15.5 7.3 0.8 3.2 2.4 1.3 3.7 1.1 1.8 1.6 1.3 3.3 1.8 1.8 1.9 11.8 0.6 3.1 1.8 1.4 1.0 9.1 11.1 10.7 12.0 8.0 9.6 8.1 6.9 9.3 5.1 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 38.4 9.0 3.7 19.5 4.9 15.5 16.3 24.4 3.8 13.7 18.7 5.9 7.7 9.3 13.8 12.2 8.3 12.5 13.4 27.5 3.8 4.8 7.4 6.7 16.3 19.1 4.4 1.9 17.7 6.8 3.4 13.5 25.4 7.9 12.9 8.0 11.6 9.1 6.3 10.3 8.5 13.8 25.6 5.7 16.4 12.4 9.2 5.2 11.6 13.5 7.0 18.0 24.9 24.1 5.1 3.1 2.8 2.1 10.3 9.9 1.6 1.6 2.2 7.6 3.7 8.7 8.8 4.9 5.6 2.8 1.6 2.7 2.9 1.9 3.6 4.0 3.0 2.8 1.0 1.0 2.0 2.7 2.9 1.9 11.7 1.8 12.8 1.3 1.4 8.4 3.0 4.4 12.0 5.5 2.0 11.5 3.5 2.0 1.9 0.9 2.7 3.2 4.1 2.3 0.6 4.0 7.2 5.8 6.4 6.7 0.8 8.8 1.6 2.9 3.1 23.4 2.0 3.2 1.3 6.5 0.5 5.6 6.2 1.2 1.5 0.7 1.5 2.8 9.9 0.9 8.8 2.2 5.1 5.6 1.3 5.1 4.4 8.0 1.0 10.3 2.1 3.1 5.6 1.6 3.7 4.9 24.4 3.8 3.8 4.8 4.4 1.9 7.9 5.2 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800634 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 66.8" "Cell line enhanced" "Detected in some" "A-431: 19.0;BEWO: 13.1;CACO-2: 12.8;CAPAN-2: 26.3;HaCaT: 18.4;HBEC3-KT: 16.0;hTCEpi: 12.2;RT4: 16.0;SK-BR-3: 14.6;T-47d: 10.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm Nucleoplasm "CAB008087: AB_2228531, HPA035266: " "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favourable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.0 0.5 8.5 0.2 0.0 4.8 0.1 0.4 4.4 39.5 0.1 3.2 29.5 1.7 1.7 22.0 1.4 18.8 0.1 0.6 0.0 4.9 15.1 1.3 0.1 0.1 0.3 0.8 18.1 0.9 0.7 4.1 0.2 6.9 6.9 0.5 11.4 5.2 0.1 20.8 66.8 0.4 0.1 0.1 10.2 1.6 0.1 0.5 1.9 13.2 15.7 7.6 8.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 12.8 26.3 0.0 0.0 0.0 18.4 0.0 16.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.0 14.6 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.4 0.6 0.0 0.1 0.3 0.2 0.1 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743697-107761667 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 15.8 12.0 11.7 13.6 20.0 38.8 16.8 18.7 19.4 15.3 17.2 19.2 11.6 10.8 22.9 9.7 14.4 14.2 10.2 11.5 11.9 10.7 11.6 12.5 12.9 16.5 12.6 14.3 18.2 15.5 14.5 17.2 13.5 16.5 18.7 13.0 14.7 12.8 19.6 32.6 16.6 14.4 16.2 15.1 15.8 14.7 21.1 13.3 29.0 15.8 11.8 19.3 17.6 12.7 17.9 16.7 32.2 15.7 23.4 40.3 20.1 13.5 15.5 12.0 15.3 11.0 9.6 8.2 10.2 10.6 11.5 11.4 10.4 13.8 19.6 14.8 11.5 9.6 16.6 12.4 15.8 13.9 10.5 16.0 11.4 8.7 12.8 23.5 15.7 10.0 11.5 15.5 17.0 11.8 25.1 16.7 11.0 23.1 32.1 16.0 17.2 10.6 14.9 13.0 20.3 8.7 12.5 12.8 20.0 15.2 22.4 11.1 7.5 12.0 11.5 17.9 12.9 16.9 15.6 27.2 29.5 31.8 11.0 14.7 15.1 32.2 14.2 23.3 19.0 14.7 28.0 17.9 30.1 21.8 16.7 17.4 20.9 19.6 21.9 23.4 15.7 9.0 40.3 20.1 11.7 20.0 18.7 19.4 11.9 10.7 12.6 14.3 16.5 13.3 CBLL2 "CT138, FLJ25735, HAKAIL, ZNF645" ENSG00000175809 "Cbl proto-oncogene like 2" Q8N7E2 X 22272943-22274461 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favourable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 12.6 9.7 10.9 9.8 13.7 14.2 27.2 14.5 16.4 20.3 13.4 13.2 17.2 9.9 20.4 24.2 17.4 18.8 12.4 33.8 11.1 11.2 31.2 34.4 15.4 11.2 13.4 11.1 49.1 20.6 14.5 12.1 14.4 15.9 18.0 14.5 15.8 14.0 12.3 20.6 14.6 10.0 27.6 15.8 11.3 13.0 9.7 13.9 11.2 35.8 15.3 16.1 33.6 17.7 9.3 13.7 3.5 3.1 4.4 10.7 3.0 6.5 5.4 30.8 29.6 15.8 21.8 24.9 8.1 16.3 12.5 16.5 18.3 7.3 23.0 5.4 5.9 11.9 21.4 15.3 16.9 6.6 18.1 13.5 5.1 17.2 46.5 24.9 12.7 29.6 25.8 8.9 86.7 9.4 16.5 18.2 8.2 10.5 14.4 17.0 18.5 10.3 17.8 15.2 9.6 13.0 9.7 24.6 25.6 5.6 13.0 36.3 4.1 18.3 4.0 7.1 9.1 8.6 10.5 8.6 10.7 15.7 2.4 21.1 8.2 3.5 3.1 0.0 6.7 1.1 9.1 9.3 7.4 8.3 13.7 8.4 7.7 10.7 0.5 4.4 1.1 13.7 9.9 3.0 10.9 13.7 14.5 16.4 11.1 11.2 13.4 11.1 15.9 13.9 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34" P49427 19 531712-542092 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370" "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavourable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 16.5 15.9 21.3 11.3 19.1 24.7 20.4 25.7 30.9 16.0 20.5 19.5 10.5 15.4 13.3 13.4 15.6 14.5 13.6 35.6 21.1 18.2 12.1 36.0 13.0 9.9 18.5 19.8 17.0 37.4 11.3 17.0 24.9 16.2 17.2 10.6 15.3 26.4 18.5 63.9 19.0 13.2 18.6 14.3 12.7 15.7 43.6 15.0 12.2 13.1 17.0 8.7 19.2 16.4 2.9 2.8 11.5 4.5 1.5 4.1 1.3 18.4 18.4 23.7 19.5 10.8 10.3 23.7 16.6 12.7 17.9 18.7 28.6 11.3 10.2 17.4 11.8 12.8 18.6 14.0 9.2 16.6 50.0 9.4 12.2 30.9 26.9 13.2 11.4 13.3 21.0 15.1 15.8 21.3 40.2 20.4 11.8 26.4 18.0 17.6 29.9 17.9 16.7 12.2 17.1 13.5 11.0 30.9 22.9 14.4 15.0 27.6 12.0 19.4 17.4 13.1 15.6 30.4 22.1 20.4 15.6 13.6 17.9 18.7 13.5 4.5 3.5 6.2 2.3 3.4 1.7 2.9 3.2 4.1 2.8 1.7 2.5 2.4 11.5 1.5 4.5 2.3 3.1 1.3 21.3 19.1 25.7 30.9 21.1 18.2 18.5 19.8 16.2 15.0 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: " "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 17.2 15.2 19.1 8.6 21.1 3.9 14.0 29.2 20.4 21.1 19.3 16.4 13.1 16.9 15.8 9.9 12.3 12.9 16.6 14.1 21.7 17.7 20.8 17.0 11.7 3.5 20.0 16.3 17.4 15.1 29.3 29.6 14.8 19.3 21.1 12.4 11.0 8.4 18.5 11.9 7.6 17.2 27.6 16.6 8.8 25.2 26.7 19.9 0.7 9.8 7.3 2.5 23.4 23.1 0.1 0.7 2.0 0.1 0.0 0.1 0.0 9.3 8.9 9.5 4.4 9.5 11.8 3.3 10.7 15.2 7.4 7.8 7.2 21.3 0.0 11.6 17.8 4.3 6.9 6.0 9.1 0.0 5.6 7.2 10.5 2.8 10.8 5.8 3.2 8.2 7.7 12.0 12.1 24.8 18.4 0.0 12.1 2.5 0.1 1.0 7.7 8.5 0.0 16.0 0.0 12.0 18.1 6.8 10.0 18.2 7.6 10.7 9.9 0.3 24.9 13.7 7.1 15.5 14.2 0.0 0.0 0.0 18.1 0.0 18.2 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 19.1 21.1 29.2 20.4 21.7 17.7 20.0 16.3 19.3 19.9 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932379-103057462 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved 12000 "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favourable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 32.2 22.7 33.1 14.8 33.2 3.1 19.8 30.3 42.1 26.7 21.8 42.3 21.5 26.0 27.0 18.7 28.3 26.0 28.1 30.7 31.4 25.5 23.7 20.1 26.4 7.9 31.2 28.4 29.7 28.8 32.5 25.9 25.6 27.0 25.1 18.2 23.7 23.0 28.8 17.0 23.8 29.6 28.7 24.3 18.3 25.5 21.8 31.0 2.1 26.3 15.9 12.4 25.2 32.6 0.9 0.2 0.0 2.0 0.0 0.4 0.1 13.1 26.4 17.0 12.4 18.9 21.7 17.1 15.1 16.0 16.0 14.8 9.0 15.5 0.0 16.6 29.4 16.8 17.5 18.0 17.1 16.0 7.9 7.2 21.3 9.0 20.6 0.0 7.8 18.7 18.7 16.4 15.8 31.1 5.8 3.7 15.4 27.6 0.1 1.6 8.1 21.8 0.0 14.3 0.3 20.5 25.9 12.4 13.5 26.8 10.1 11.3 15.6 4.6 39.5 15.4 10.4 34.0 14.0 4.9 5.2 3.8 17.3 1.6 14.9 0.0 1.4 0.0 0.0 2.0 0.0 0.9 0.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 33.1 33.2 30.3 42.1 31.4 25.5 31.2 28.4 27.0 31.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823387-64844569 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 19.1;HaCaT: 14.3;MCF7: 19.3;RT4: 11.7;SK-BR-3: 11.9;T-47d: 11.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 19.4" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 4 "cerebellum: 5.9" "Low region specificity" "Detected in single" "HPA027382, HPA061836" Enhanced Supported Cytosol Cytosol "HPA027382: AB_1846378, HPA061836: " "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favourable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 2.7 0.8 2.1 0.5 1.1 3.5 19.4 0.8 2.9 9.1 0.8 6.3 8.2 1.0 8.0 14.3 2.9 10.5 0.5 0.7 0.0 3.5 0.5 4.2 0.7 0.5 0.5 1.5 7.9 7.0 6.5 13.0 2.0 4.4 3.4 1.0 14.3 7.6 0.5 22.4 19.7 1.6 0.8 0.8 8.5 2.5 0.7 1.8 3.9 8.1 7.7 5.4 6.3 0.4 0.0 0.0 0.0 0.2 1.0 0.1 5.5 0.8 0.5 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 7.4 4.7 0.1 2.8 0.0 14.3 0.8 5.6 0.0 0.2 2.2 0.4 3.1 2.3 0.0 0.1 1.4 0.0 7.0 0.0 0.1 0.0 3.7 0.0 0.0 19.3 0.1 1.0 1.7 0.8 0.8 0.3 2.6 3.4 11.7 10.2 0.5 1.8 11.9 0.3 11.6 0.2 0.0 0.0 2.0 0.0 0.0 1.3 1.3 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.8 0.5 19.4 0.8 0.7 0.0 0.5 0.5 2.0 0.7 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500893-91525764 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: " "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavourable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 2.5 3.7 5.7 7.6 8.9 15.4 4.3 19.4 10.3 2.5 4.2 1.4 0.9 4.2 2.8 2.6 4.7 1.7 2.6 1.9 6.8 5.2 3.6 2.3 5.1 11.7 4.0 4.7 3.7 2.4 2.2 12.3 7.9 5.2 2.7 6.8 2.3 2.5 2.3 1.0 6.8 4.9 3.3 5.9 15.1 2.6 21.2 4.7 18.7 2.5 4.5 12.0 4.2 3.0 1.6 3.5 0.1 1.6 2.4 6.5 2.1 14.0 4.2 27.1 7.7 0.6 3.6 8.6 5.3 4.2 10.5 11.5 8.7 5.0 9.7 7.5 3.3 6.1 17.8 6.0 14.6 16.1 15.3 14.8 12.0 4.1 1.0 16.1 5.4 1.9 1.8 9.6 5.5 4.0 19.5 14.2 7.2 5.1 13.7 14.4 22.5 9.9 17.1 22.5 6.2 4.6 10.6 21.6 8.5 16.9 4.7 9.4 4.4 7.9 3.3 12.0 10.6 9.2 8.0 5.2 6.6 26.1 4.3 15.6 4.4 0.0 1.6 0.0 5.9 1.2 5.2 1.5 4.5 5.6 3.5 1.6 2.5 5.1 0.1 2.4 0.3 2.1 6.5 2.1 5.7 8.9 19.4 10.3 6.8 5.2 4.0 4.7 5.2 4.7 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 88.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 6.1;T-reg: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;NK-cells: 6.1;T-cells: 5.7" "Low region specificity" "Detected in single" "HPA003387, CAB003799" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003799: AB_344898, HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favourable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavourable (1.10e-6)" "prognostic unfavourable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavourable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 4.1 2.2 0.8 17.8 2.4 17.8 4.4 0.7 1.6 4.2 6.5 1.1 3.4 6.1 2.9 4.8 19.0 1.5 2.4 2.3 0.9 0.7 3.1 1.7 5.7 15.1 1.7 0.6 2.2 1.0 0.5 4.4 13.3 1.2 1.5 8.3 1.0 3.8 2.9 1.0 4.9 8.3 2.7 2.5 8.3 5.0 13.8 1.2 88.4 1.8 16.7 20.1 3.2 6.9 0.9 1.7 0.0 0.2 6.1 5.7 1.8 48.2 18.4 48.9 19.3 3.2 4.9 20.1 36.5 26.6 44.5 42.9 43.0 42.7 44.2 14.2 10.0 30.0 33.2 21.2 46.4 31.4 24.2 23.2 18.1 24.9 0.5 35.5 24.0 0.9 2.1 28.8 28.1 26.7 35.3 54.5 49.5 12.8 44.6 25.5 21.5 38.7 38.8 45.5 21.7 17.0 16.0 22.9 20.1 24.5 37.3 18.9 40.2 21.8 11.0 19.0 40.6 20.0 49.8 21.4 34.3 39.9 16.4 39.8 23.6 0.0 0.0 0.0 0.5 0.2 0.5 0.9 1.5 2.7 0.5 0.5 0.5 1.5 0.0 6.1 0.2 1.7 5.7 1.8 0.8 2.4 0.7 1.6 0.9 0.7 1.7 0.6 1.2 1.2 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Nucleoplasm "Midbody, Midbody ring" "HPA007451: , HPA059634: , HPA067060: " "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favourable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favourable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.5 9.5 7.7 3.1 3.2 6.1 8.0 12.0 6.8 8.6 2.9 7.3 11.1 12.9 6.2 10.4 10.2 3.3 16.8 5.4 2.8 8.0 5.1 10.6 0.8 13.2 8.2 9.3 7.4 5.6 5.4 8.2 15.0 13.3 1.7 9.8 19.0 9.9 23.5 15.6 7.2 14.4 10.4 18.1 15.4 11.6 7.5 16.3 15.1 7.0 3.5 16.5 13.0 13.2 5.9 15.1 6.1 8.2 6.6 3.6 4.0 8.9 14.2 8.3 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702730-1724324 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.5" "Low lineage specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: " "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavourable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavourable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 14.3 14.9 17.2 23.7 26.9 39.7 13.0 35.2 32.7 12.5 16.4 14.3 6.1 29.2 16.5 8.5 12.1 12.6 10.2 10.2 19.4 8.4 11.7 12.5 19.0 20.3 22.6 9.0 16.2 12.9 12.2 27.5 12.9 17.1 14.4 14.6 11.6 12.7 10.3 21.5 15.1 34.9 13.1 26.0 24.2 15.7 16.4 25.1 14.9 14.6 7.6 22.4 13.5 15.2 7.4 11.8 33.5 6.3 4.4 5.5 1.4 16.1 9.7 7.0 6.4 9.2 7.4 6.9 15.9 7.1 7.9 9.2 12.2 14.8 17.2 9.7 4.6 12.0 6.5 8.2 6.3 13.1 10.4 15.3 18.3 10.9 6.1 17.1 22.1 8.5 5.6 6.9 4.5 13.6 17.9 14.4 6.6 9.1 7.9 13.4 9.7 8.3 14.5 10.7 8.3 6.4 7.3 7.8 11.3 13.9 16.4 19.1 11.0 7.1 13.8 12.5 12.1 5.6 8.8 20.1 14.6 21.6 4.2 13.9 3.9 16.7 6.3 7.7 5.5 3.4 4.2 6.2 4.7 4.2 2.0 7.4 4.7 4.0 33.5 4.4 3.7 11.8 4.5 1.4 17.2 26.9 35.2 32.7 19.4 8.4 22.6 9.0 17.1 25.1 CDK11B "CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58" ENSG00000248333 "Cyclin dependent kinase 11B" 1 1635227-1659012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA025061, HPA073626" Approved Approved "Nuclear speckles" "Nuclear speckles" "HPA025061: AB_1846407, HPA073626: " "unprognostic (7.52e-3)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "prognostic favourable (1.14e-4)" "unprognostic (9.75e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (6.04e-2)" "unprognostic (8.45e-2)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (6.52e-3)" 10.5 9.8 10.4 11.7 15.1 24.3 8.6 15.0 14.1 9.0 13.3 11.6 6.7 17.4 11.0 6.1 8.6 7.3 7.5 11.2 12.2 9.3 7.9 8.3 12.8 13.1 11.4 9.7 10.3 11.8 9.1 9.6 8.3 11.0 8.9 7.1 7.0 14.0 9.5 33.7 14.0 18.0 14.0 14.8 12.9 9.6 15.8 13.1 12.2 9.5 8.3 10.3 11.6 11.8 5.2 6.2 16.4 4.2 5.1 8.0 2.1 20.6 16.8 12.8 10.2 12.2 8.1 14.3 20.2 11.2 15.8 13.7 18.7 23.4 19.3 20.1 10.0 18.9 11.8 11.9 9.3 17.5 20.5 20.3 31.2 16.8 14.3 23.1 24.5 10.1 8.1 14.8 11.8 12.9 24.6 13.8 8.2 14.5 22.7 22.4 19.3 20.7 23.4 21.1 15.4 8.5 8.2 14.6 17.8 19.4 20.0 21.3 14.9 17.1 17.9 15.5 16.5 10.5 19.4 28.5 25.2 39.0 18.0 28.0 10.7 8.2 4.2 6.3 8.0 3.6 4.1 4.2 5.1 5.4 3.1 5.2 5.9 4.4 16.4 5.1 3.8 6.2 4.1 2.1 10.4 15.1 15.0 14.1 12.2 9.3 11.4 9.7 11.0 13.1 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.7 10.8 6.5 6.1 4.8 5.4 6.1 7.9 6.7 10.9 8.1 13.3 5.4 12.4 7.0 8.3 14.2 13.0 10.0 10.5 8.1 11.2 13.4 7.4 10.3 4.7 18.3 9.4 5.8 6.9 13.2 10.5 6.6 22.7 8.2 6.2 4.1 14.9 4.7 6.8 4.9 9.9 14.1 7.0 4.1 10.5 7.0 4.5 10.1 85.6 6.9 11.0 7.9 7.1 9.9 7.9 6.9 10.2 6.7 4.8 17.5 7.0 7.8 6.4 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39949646-40099580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA059241: " "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 16.9 15.3 16.0 29.0 14.5 26.7 20.4 23.3 18.2 16.6 18.3 16.4 14.2 11.3 20.3 17.7 20.9 18.1 20.2 13.6 14.3 11.3 14.7 17.5 19.6 21.9 16.5 15.1 24.2 15.3 26.3 15.3 14.8 12.0 15.5 15.5 14.9 17.6 14.5 19.4 16.7 16.3 16.4 11.5 17.4 14.5 20.2 15.7 31.2 23.1 14.6 21.5 18.5 23.6 14.0 3.9 7.9 3.4 5.0 5.0 1.4 15.6 9.3 16.3 15.5 14.7 14.4 11.2 12.5 13.6 11.5 14.4 9.7 10.8 28.4 7.3 13.1 19.1 13.3 11.0 17.0 13.9 9.8 12.6 11.4 8.8 14.1 19.2 13.8 8.5 14.8 13.1 17.6 13.5 21.3 19.7 11.9 8.0 15.2 13.6 23.5 10.9 16.9 10.8 11.4 10.8 15.8 11.6 16.8 15.9 34.4 11.3 14.1 23.9 16.0 15.9 15.2 10.2 17.0 16.2 13.7 23.4 11.6 17.4 20.2 7.9 2.7 4.4 5.0 2.2 3.4 7.6 4.8 3.7 1.5 14.0 4.9 4.9 7.6 5.0 3.4 3.9 4.3 1.4 16.0 14.5 23.3 18.2 14.3 11.3 16.5 15.1 12.0 15.7 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 7.5;memory B-cell: 9.8;naive B-cell: 5.3;neutrophil: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 9.8;granulocytes: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favourable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavourable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 8.2 4.7 19.8 7.1 19.4 6.1 8.3 28.6 34.9 10.6 5.2 3.7 0.6 2.7 8.6 3.2 3.1 12.0 11.9 11.5 25.8 15.5 19.8 12.7 9.2 10.9 17.3 17.4 14.9 14.2 3.8 14.2 5.9 22.8 11.3 3.4 4.3 7.7 7.0 5.4 2.7 3.8 7.4 7.0 7.5 7.4 7.2 4.5 0.9 13.1 1.6 11.9 6.9 6.7 9.8 0.9 7.5 0.7 0.1 0.2 0.6 7.0 0.0 14.1 1.8 13.2 13.4 3.2 5.9 5.6 3.6 3.9 0.1 3.4 25.0 0.7 5.8 2.1 0.7 8.3 7.0 0.0 3.3 0.0 4.7 0.1 6.1 7.1 0.1 9.5 2.1 10.8 3.9 4.6 0.1 30.8 7.3 0.0 0.0 2.7 8.9 3.8 19.2 19.4 19.0 1.9 1.9 3.1 9.1 15.0 0.0 0.3 1.9 3.6 11.3 15.7 20.1 13.1 9.0 17.4 13.3 17.9 5.9 9.4 15.3 7.5 0.3 0.5 0.0 0.7 0.0 9.8 0.0 0.0 0.9 5.3 0.0 0.0 5.6 0.1 0.5 0.1 0.2 0.6 19.8 19.4 28.6 34.9 25.8 15.5 17.3 17.4 22.8 4.5 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2;ovary: 9.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.9;HBF TERT88: 18.2;HMC-1: 34.4;LHCN-M2: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 52 "basophil: 3.5;eosinophil: 6.9" "Lineage enriched" "Detected in single" 69 "granulocytes: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 1.3 0.2 0.1 5.2 0.1 0.0 3.7 0.3 0.1 3.4 2.3 0.1 0.1 0.3 4.1 20.2 1.1 1.0 4.2 0.3 0.1 0.0 0.4 0.1 3.3 0.1 0.1 0.1 9.8 0.2 0.0 0.5 0.1 0.1 2.0 0.7 1.4 0.6 0.3 0.7 1.1 3.0 3.9 0.1 0.1 1.1 2.5 0.1 0.1 0.2 1.2 1.2 1.6 1.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.7 0.0 3.1 14.6 5.5 11.9 0.0 1.5 0.0 0.0 1.3 0.0 0.0 0.0 18.2 0.0 0.0 1.0 0.0 0.0 0.2 0.0 34.4 2.0 0.0 1.5 0.7 0.0 0.0 0.0 10.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Uncertain "Plasma membrane,Microtubules,Cytosol" "Plasma membrane, Microtubules, Cytosol" "CAB016535: AB_785112, HPA000974: , HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 41.2 31.7 30.4 44.9 22.3 19.2 30.4 19.6 24.2 29.9 22.3 35.6 20.0 9.9 12.5 35.2 23.4 32.3 41.8 20.2 11.9 51.3 10.8 44.5 27.7 29.0 11.3 25.2 23.9 26.8 42.4 51.2 26.7 16.0 16.9 26.1 35.9 9.8 26.0 23.8 34.2 10.5 24.1 17.4 22.5 32.7 25.7 19.4 53.3 41.3 20.2 36.8 13.9 26.8 20.0 32.8 30.5 23.4 13.3 13.0 9.7 17.6 52.7 22.4 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400560 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 43.7;TIME: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavourable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 16.3 9.1 20.6 13.9 47.0 31.5 14.7 17.8 35.7 11.8 12.9 23.6 3.4 9.2 20.7 7.5 11.7 10.9 12.9 9.4 25.3 17.3 9.2 12.4 15.9 15.2 23.8 21.0 12.9 8.0 9.9 7.3 24.3 14.8 11.4 9.8 5.7 7.5 9.3 7.3 9.1 9.3 23.4 19.6 15.8 7.9 19.9 28.0 29.6 9.4 6.1 16.6 11.0 10.7 9.6 5.3 29.1 4.7 16.5 14.8 8.6 4.8 4.1 10.8 2.9 5.3 14.0 7.7 10.9 15.4 9.6 9.1 2.4 2.8 7.2 7.6 7.9 4.4 6.4 6.7 13.2 7.6 4.9 10.4 2.8 3.4 11.5 5.5 6.0 10.2 7.0 14.2 25.7 43.7 7.6 5.9 21.7 3.0 5.2 8.7 4.7 7.2 9.1 5.8 6.2 11.4 4.1 5.6 3.8 6.4 6.0 7.9 4.6 5.0 52.4 8.6 3.3 4.6 5.9 8.3 6.3 7.8 3.2 2.4 6.3 29.1 3.4 8.9 12.7 4.7 13.7 9.6 10.4 14.4 5.3 8.8 14.8 12.6 12.8 16.5 4.6 3.9 8.1 8.6 20.6 47.0 17.8 24.6 25.3 17.3 23.8 21.0 14.8 28.0 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504595-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;heart muscle: 58.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 20.9;HeLa: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favourable (2.81e-5)" 2.6 4.3 13.6 2.7 31.8 1.0 2.4 4.2 25.0 7.6 6.9 38.1 20.2 17.3 3.4 4.0 2.7 5.7 6.4 58.9 22.1 16.2 13.7 4.7 6.5 1.9 47.8 16.7 7.5 10.7 3.7 4.0 9.6 22.1 3.1 6.1 5.3 16.5 23.5 3.9 1.6 15.1 4.8 98.7 3.5 9.1 0.9 36.4 0.4 4.8 1.4 2.5 3.7 4.7 0.1 1.4 0.0 2.1 0.6 0.9 0.6 12.2 0.8 0.1 0.6 0.0 0.0 13.2 0.2 2.5 0.6 3.2 5.5 9.2 7.3 1.8 0.1 11.0 2.7 20.9 0.5 2.0 2.4 1.7 18.4 5.6 2.3 0.0 0.0 1.4 1.1 0.0 0.4 0.0 0.1 8.8 0.1 9.9 0.7 0.3 10.4 0.4 0.9 0.0 9.1 2.0 7.8 4.3 1.7 3.7 1.8 8.1 8.2 3.5 0.0 0.0 5.0 0.1 0.0 2.5 1.2 1.5 0.1 5.2 2.1 0.0 0.8 0.0 0.1 2.1 0.9 0.0 0.2 0.0 1.4 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.6 13.6 31.8 4.2 19.7 22.1 16.2 47.8 16.7 22.1 36.4 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007053 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA007053: AB_1846369" "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavourable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavourable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 5.3 3.3 18.1 6.1 29.4 9.7 6.0 13.8 21.3 6.6 6.3 31.1 2.4 4.8 9.6 3.7 7.8 5.3 7.8 4.1 20.8 10.1 6.3 4.6 6.2 8.0 22.1 12.9 9.7 3.1 8.0 4.1 10.5 14.4 25.8 6.1 3.4 4.5 5.9 3.2 7.9 5.9 7.1 20.8 7.0 6.5 16.4 26.3 6.1 5.8 1.3 8.4 5.9 6.4 1.3 1.8 8.5 2.2 1.3 0.8 0.6 3.6 3.8 13.4 16.2 7.3 10.5 7.0 11.6 12.4 4.4 5.8 4.8 4.0 9.1 4.2 8.2 2.1 5.1 2.5 10.1 11.3 3.0 15.6 5.7 5.6 4.4 6.3 11.7 7.2 5.5 6.0 9.3 4.3 4.7 12.8 9.4 5.8 8.4 9.4 1.3 2.6 9.1 6.9 3.5 5.1 6.6 6.9 12.8 8.9 7.2 10.4 2.4 23.2 4.8 9.2 4.9 18.6 7.1 1.4 1.8 7.9 9.7 8.5 9.5 3.3 2.2 1.5 0.8 1.2 0.8 1.1 0.7 0.7 1.8 1.3 0.5 0.7 8.5 1.3 0.7 0.9 0.8 0.6 18.1 29.4 13.8 21.3 20.8 10.1 22.1 12.9 14.4 26.3 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966769-55972784 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 105.5" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: " "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (9.94e-4)" "prognostic unfavourable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavourable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 10.7 7.6 4.5 20.8 6.5 18.7 11.5 4.2 4.3 12.6 11.6 3.5 6.0 6.1 10.7 6.4 13.6 10.8 12.6 10.1 5.4 2.2 8.3 16.7 19.5 12.2 6.0 2.0 14.2 8.3 5.2 4.2 49.0 7.3 10.8 9.1 51.2 9.3 9.9 10.8 14.6 9.3 11.8 5.0 12.5 10.1 7.8 5.1 39.3 9.5 10.7 14.7 16.7 10.1 9.3 10.8 5.2 3.9 4.5 7.6 4.3 16.5 8.9 19.6 10.9 4.0 5.2 36.2 20.6 10.8 25.6 24.0 18.7 15.9 15.7 15.5 7.6 10.6 14.9 9.0 26.1 18.5 14.6 18.1 14.8 7.1 1.3 14.3 13.1 2.7 2.3 17.3 6.0 12.9 17.2 14.3 17.8 12.7 29.6 12.1 7.8 13.3 29.0 18.9 11.8 7.4 16.2 8.1 10.5 23.5 8.6 105.5 18.6 10.5 7.2 17.7 17.2 13.6 15.0 8.2 9.4 19.6 10.0 10.5 15.2 5.2 3.6 3.1 7.0 3.9 7.0 9.3 3.2 5.0 2.7 6.1 3.0 5.3 1.7 4.5 1.6 10.8 7.6 4.3 4.5 6.5 4.2 4.3 5.4 2.2 6.0 2.0 7.3 5.1 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SCLC-21H: 14.4;THP-1: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.2" "Group enriched" "Detected in many" 7 "NK-cells: 7.2;T-cells: 5.0" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favourable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favourable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.6 16.2 10.8 2.4 13.0 1.6 4.1 8.7 17.1 8.7 5.0 6.1 5.1 5.3 7.2 6.0 2.8 19.5 5.6 3.0 8.6 10.7 8.2 3.2 4.0 2.0 5.8 14.3 9.5 4.8 7.6 10.8 3.1 9.3 6.1 3.4 7.7 3.6 8.6 2.1 3.6 7.6 5.5 3.1 1.6 3.7 17.7 5.2 0.8 6.8 1.2 1.1 6.3 3.0 0.1 0.8 0.4 0.8 7.2 5.0 1.3 2.3 3.0 2.4 7.6 1.7 2.4 1.0 2.1 4.2 5.8 5.4 0.7 3.5 0.0 3.3 3.5 3.1 0.0 2.1 2.4 5.9 2.4 0.0 1.9 0.0 7.4 2.8 3.3 1.9 4.4 9.2 3.8 0.0 0.3 0.0 1.7 7.0 1.9 0.8 1.9 1.1 0.0 0.0 0.1 7.4 2.0 14.4 4.0 2.5 3.0 3.6 3.3 21.6 0.0 2.6 1.0 0.5 2.4 3.8 3.6 0.0 9.3 1.9 2.7 0.0 0.7 0.4 1.3 0.8 0.5 0.0 3.0 1.9 0.7 0.1 5.0 3.2 0.1 7.2 0.7 0.8 2.7 1.3 10.8 13.0 8.7 17.1 8.6 10.7 5.8 14.3 9.3 5.2 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 4.1 3.7 2.7 4.7 2.4 5.5 4.7 4.2 2.4 4.9 4.8 6.5 5.6 5.7 4.0 5.0 4.8 2.6 2.8 3.0 5.9 13.0 5.3 5.5 3.0 6.7 5.9 4.2 8.3 5.0 10.3 5.3 5.2 4.5 0.9 14.7 9.1 4.1 3.9 8.8 5.2 5.6 8.2 5.4 3.8 5.1 1.2 1.8 1.5 1.5 1.7 2.7 1.6 4.2 7.7 11.5 6.0 6.8 8.0 23.9 5.2 3.4 5.9 5.5 6.0 8.8 6.3 4.6 4.5 9.7 9.2 3.9 3.8 3.2 14.8 13.2 15.3 6.0 5.6 4.6 13.5 7.2 8.5 5.2 4.2 6.4 5.8 4.5 3.7 10.7 5.3 20.4 5.7 8.4 9.9 5.0 5.9 5.4 14.0 8.3 22.4 3.5 11.3 2.5 15.5 9.3 5.4 15.9 9.4 6.7 5.5 9.5 7.1 5.9 4.8 4.7 3.9 0.0 1.5 0.0 2.1 1.0 0.2 1.2 1.6 1.2 1.8 0.3 2.7 0.5 1.5 1.7 0.6 1.6 2.7 1.6 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 125.1;LHCN-M2: 138.1;RH-30: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: " "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.3 10.8 14.3 12.7 13.1 11.5 9.5 5.4 17.6 23.8 19.8 15.4 8.9 13.6 9.7 8.4 7.2 19.7 125.1 18.1 6.7 9.1 12.7 7.3 10.8 15.4 14.4 8.8 11.3 9.2 14.6 16.8 15.3 13.5 11.7 138.1 13.5 13.7 11.7 16.8 11.0 12.4 434.6 12.6 7.4 14.7 12.9 12.1 9.5 7.2 14.4 9.6 17.5 6.9 11.2 10.5 12.6 10.9 5.8 9.5 20.9 10.3 13.3 13.4 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053812-151058530 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB008909: , HPA064535: " "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 4.5 11.3 24.4 6.9 30.4 6.1 5.3 13.6 36.1 5.3 6.1 6.7 4.5 7.9 4.5 17.4 6.5 5.0 6.2 5.8 25.0 19.7 9.0 7.7 5.3 6.0 15.4 15.4 3.2 5.8 8.9 7.9 5.3 20.8 5.8 6.3 3.2 6.0 6.3 5.7 6.5 6.2 6.0 8.6 5.2 5.7 3.1 7.7 6.8 6.0 3.6 6.9 6.7 3.1 6.6 21.5 9.0 21.7 9.5 14.9 10.6 11.6 14.0 13.1 21.3 14.5 10.7 6.5 7.7 12.8 15.2 12.6 9.9 10.9 11.5 27.7 9.5 8.3 21.0 11.8 7.0 9.1 12.5 12.6 12.3 9.8 9.6 10.2 23.7 11.5 8.8 12.5 3.9 10.2 12.8 8.4 15.2 22.6 27.4 20.8 14.4 22.1 13.4 5.4 12.8 13.2 8.8 8.3 35.7 11.1 13.7 14.6 6.4 9.0 8.6 15.0 3.9 11.2 14.4 19.6 21.4 4.5 23.6 14.7 26.8 7.8 19.0 9.0 6.9 21.7 5.4 6.6 6.8 6.8 21.5 5.9 5.1 6.2 2.8 9.5 16.4 12.8 14.9 10.6 24.4 30.4 13.6 36.1 25.0 19.7 15.4 15.4 20.8 7.7 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.6" "Cell line enhanced" "Detected in many" "MOLT-4: 91.7;REH: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavourable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavourable (2.33e-5)" 6.6 11.3 6.0 9.1 7.5 22.5 5.9 2.4 6.0 7.8 10.0 9.6 5.7 7.5 6.0 5.9 8.5 4.6 7.8 6.6 6.9 4.2 6.5 7.5 7.3 7.4 7.0 5.2 5.0 10.0 25.7 4.2 20.5 7.5 6.1 9.2 4.4 10.9 6.1 2.0 11.6 9.4 9.8 7.5 6.3 10.8 5.4 8.0 74.6 4.3 9.2 10.3 6.7 9.0 3.6 5.6 6.5 4.8 3.9 7.1 2.3 6.0 2.8 7.8 5.0 2.3 2.6 1.6 6.3 3.9 3.1 3.0 7.7 4.7 4.7 3.6 4.2 3.8 4.3 9.0 7.4 10.3 3.0 11.8 5.4 7.4 1.4 7.3 0.5 2.5 4.9 4.2 20.0 1.2 11.2 13.0 5.6 1.2 91.7 0.7 2.4 2.6 44.8 27.6 7.9 4.3 0.1 4.1 26.8 0.7 2.1 3.7 0.1 12.0 4.6 10.3 16.1 4.0 12.6 7.0 0.1 6.3 1.5 25.0 13.6 4.9 1.9 6.5 5.2 3.9 5.9 2.0 5.5 5.6 4.0 3.6 7.1 4.0 1.1 3.9 4.8 5.6 2.8 2.3 6.0 7.5 2.4 6.0 6.9 4.2 7.0 5.2 7.5 8.0 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932" Enhanced "CAB004364: AB_627243, HPA007932: AB_1078492" "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavourable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavourable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 7.9 12.9 10.9 6.2 15.2 44.1 14.0 10.8 14.7 9.4 12.7 6.0 6.3 15.8 9.4 8.6 23.4 18.5 16.5 8.1 11.5 9.3 13.8 10.6 10.1 8.8 7.6 9.7 7.7 9.1 3.3 16.2 22.9 11.2 11.2 14.8 6.6 13.2 6.5 15.9 15.4 9.8 12.1 9.2 7.9 13.9 29.0 7.8 12.1 20.0 15.6 15.5 10.7 11.7 15.6 15.0 22.4 11.3 12.4 15.3 7.8 3.7 7.8 1.8 0.5 2.4 11.6 14.7 6.5 7.7 10.8 17.5 16.7 1.9 2.8 10.2 1.7 2.5 1.4 2.8 5.9 1.3 7.0 0.4 8.2 7.9 0.4 6.7 3.2 14.3 13.9 9.0 2.8 13.6 10.4 4.5 4.9 0.7 4.1 14.8 1.7 7.5 6.7 0.4 1.1 1.6 1.0 0.6 6.5 1.5 5.8 3.4 11.6 0.6 2.6 0.1 3.2 0.9 5.1 4.8 8.4 3.7 0.8 4.0 0.8 7.3 10.9 22.4 8.6 11.3 14.8 12.4 12.9 15.3 15.0 15.6 11.1 13.2 10.0 12.4 8.0 11.2 12.8 7.8 10.9 15.2 10.8 12.7 11.5 9.3 7.6 9.7 11.2 7.8 CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26405238 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm Nucleoplasm "HPA044721: " "unprognostic (3.28e-3)" "unprognostic (2.25e-3)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (2.30e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (2.12e-1)" "prognostic favourable (9.23e-4)" "unprognostic (1.43e-2)" "unprognostic (1.88e-1)" "unprognostic (6.37e-2)" 7.6 8.8 10.1 10.4 8.5 5.2 5.6 26.9 11.3 5.9 24.0 6.0 13.8 13.8 11.2 6.5 10.0 7.0 11.2 7.6 8.3 7.3 9.4 10.4 6.7 5.2 7.8 7.9 6.1 12.7 8.4 10.2 10.6 8.2 7.8 11.2 4.6 9.0 19.2 9.7 6.1 15.0 12.7 6.0 6.4 11.7 16.3 9.9 12.8 6.4 6.9 7.2 15.5 11.0 1.9 1.7 3.4 1.6 1.0 2.1 1.3 6.8 5.6 11.4 11.6 6.0 7.5 7.0 13.2 9.1 9.8 7.1 16.3 9.6 7.3 5.8 6.8 8.4 13.1 8.9 12.4 16.8 7.2 13.8 4.6 5.6 4.2 21.6 7.9 5.4 8.5 7.4 12.4 7.1 21.4 0.0 8.8 7.3 16.5 10.2 9.1 7.0 10.4 11.3 5.0 5.7 6.4 9.7 5.7 5.6 10.7 9.7 3.8 9.9 7.3 6.3 8.0 11.5 7.1 5.6 9.9 13.4 3.9 9.1 7.4 0.4 0.9 3.4 1.1 1.6 1.9 1.0 1.5 2.1 1.7 1.9 2.1 1.7 0.0 1.0 1.2 1.0 0.6 1.3 10.1 8.5 26.9 11.3 8.3 7.3 7.8 7.9 8.2 9.9 CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" Nucleoplasm "Cytoplasmic bodies" "CAB004216: AB_627245, HPA006738: AB_1078493" "unprognostic (3.60e-1)" "unprognostic (1.71e-1)" "unprognostic (5.44e-3)" "unprognostic (1.04e-3)" "unprognostic (1.93e-1)" "unprognostic (3.97e-2)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.66e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "prognostic unfavourable (8.92e-4)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (8.78e-3)" 26.2 27.0 22.8 18.9 22.4 33.9 17.4 31.0 26.8 23.1 21.9 22.9 24.7 16.6 22.5 20.1 22.7 29.1 21.5 22.9 26.3 23.4 18.5 48.7 23.3 26.6 23.4 18.8 43.7 29.1 15.5 28.4 19.8 20.6 20.7 10.8 18.7 20.6 21.6 14.6 26.6 21.4 21.0 17.9 29.0 17.7 22.3 16.1 29.3 25.8 18.3 24.2 17.0 17.6 6.0 8.9 5.1 6.4 18.6 9.9 2.9 8.8 16.1 10.1 11.1 11.5 9.0 13.2 9.1 13.4 9.5 8.6 11.9 10.0 15.5 10.7 10.3 17.9 6.6 14.9 3.6 13.9 8.0 14.5 17.4 9.8 16.8 14.0 23.3 15.8 18.2 10.1 11.4 19.6 12.5 20.9 8.5 23.3 15.3 21.1 22.3 17.2 44.3 8.6 22.3 13.8 9.9 10.0 11.9 13.7 14.5 8.2 18.2 13.3 22.4 11.4 12.9 9.8 8.8 38.1 29.2 13.9 10.7 9.6 10.4 3.7 3.4 4.9 9.9 4.5 9.9 3.5 5.6 7.9 4.4 6.0 6.3 7.7 5.1 18.6 6.4 8.9 3.8 2.9 22.8 22.4 31.0 26.8 26.3 23.4 23.4 18.8 20.6 16.1 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50329404-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 16.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA059605: , HPA065919: " "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 7.1 2.1 7.5 1.8 5.1 0.9 3.0 2.7 20.2 14.1 5.9 1.6 2.5 8.4 12.1 2.3 2.6 16.4 2.6 2.9 7.1 2.4 18.8 1.1 4.3 3.0 2.0 12.3 10.5 2.0 1.4 1.4 4.9 2.9 4.0 5.7 1.6 2.5 8.4 1.7 3.0 3.0 7.7 3.1 3.7 2.0 1.9 1.4 1.3 5.0 6.1 2.1 7.0 5.6 5.7 1.3 6.0 2.5 3.8 6.7 2.6 6.0 4.8 0.6 2.4 6.5 7.8 0.3 2.1 3.8 2.2 2.5 1.9 5.7 0.4 2.6 4.6 4.2 0.9 0.6 2.5 6.6 2.3 6.4 2.1 1.7 7.3 5.8 3.5 1.7 3.5 4.5 10.0 8.4 2.6 2.6 1.0 0.3 1.9 3.1 0.7 2.3 0.7 2.8 1.8 6.9 2.3 1.1 1.3 2.4 16.5 0.6 0.2 4.9 2.6 5.7 2.9 5.6 4.7 0.8 0.4 0.4 0.9 6.1 6.9 6.0 2.5 4.4 6.3 2.3 6.2 4.6 4.4 6.7 1.3 5.7 3.4 3.7 1.4 3.8 0.3 1.2 4.1 2.6 7.5 5.1 2.7 20.2 7.1 2.4 2.0 12.3 2.9 1.4 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75578005-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.7" "Cell line enhanced" "Detected in some" "A-431: 5.6;HEK 293: 3.7;HHSteC: 4.3;RPTEC TERT1: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.7 2.4 7.1 1.2 11.1 0.7 1.2 7.7 13.2 1.7 2.0 6.2 0.0 1.0 1.7 2.3 2.3 4.1 1.4 1.3 5.1 6.7 11.8 0.7 9.2 1.3 7.1 7.0 3.8 1.6 5.7 8.9 0.7 12.5 2.0 2.4 3.4 1.2 2.0 0.7 0.9 0.9 1.5 7.4 0.9 1.5 27.7 6.1 0.0 6.9 0.0 2.0 1.1 0.9 0.4 0.0 0.2 0.0 0.0 1.6 0.1 5.6 0.7 0.3 0.0 0.3 0.3 0.0 0.3 1.7 2.4 1.9 0.5 1.2 0.1 0.9 0.1 0.8 0.0 0.5 2.2 0.2 3.7 0.0 0.2 0.0 4.3 0.0 0.1 1.4 2.1 0.4 0.8 0.1 0.0 0.4 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 8.1 0.3 3.0 2.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.4 1.6 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 1.2 0.1 7.1 11.1 7.7 13.2 5.1 6.7 7.1 7.0 12.5 6.1 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027751 Uncertain Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 2.5 2.7 7.0 2.2 7.1 1.6 2.5 7.0 8.5 2.6 2.4 5.9 5.5 2.3 3.9 5.3 2.6 3.7 2.6 6.6 6.1 6.5 4.5 2.8 2.2 2.5 8.0 4.3 3.0 2.4 3.2 6.5 2.2 8.6 2.8 2.6 3.9 2.0 3.2 7.5 2.7 2.5 4.6 8.4 2.7 2.2 33.4 9.3 1.3 3.9 2.1 3.0 2.8 2.2 1.5 2.7 1.0 1.1 1.4 4.0 1.3 1.0 2.2 3.3 2.2 5.6 4.8 1.4 3.0 2.7 1.4 3.3 2.0 1.5 2.8 1.9 1.9 0.9 2.7 1.9 2.7 3.0 2.1 1.5 2.4 3.4 3.4 0.6 1.0 2.2 4.9 4.1 1.3 1.3 1.5 1.2 3.6 1.1 2.1 8.3 2.2 1.0 3.6 1.4 0.8 1.8 1.0 5.0 1.5 2.2 0.6 3.6 1.9 1.7 1.0 2.7 0.6 3.6 1.0 3.4 4.5 5.4 4.1 2.2 2.1 0.0 0.9 1.0 0.9 1.1 4.0 1.5 1.4 2.5 2.7 1.0 3.8 3.8 0.2 1.4 0.4 1.6 2.3 1.3 7.0 7.1 7.0 8.5 6.1 6.5 8.0 4.3 8.6 9.3 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 3.2;testis: 7.9" "Cell line enhanced" "Detected in some" "HAP1: 1.8;HL-60: 4.9;RT4: 3.3;SH-SY5Y: 6.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.6;T-reg: 3.2" "Group enriched" "Detected in many" 25 "B-cells: 1.6;T-cells: 3.2" "Low region specificity" "Detected in many" HPA067895 Uncertain "HPA067895: " "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.3 1.1 0.3 0.0 0.6 0.0 0.3 0.1 0.7 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.5 0.9 0.2 0.0 0.4 0.1 0.2 0.3 0.3 0.0 1.6 1.2 0.4 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.3 7.9 0.3 0.1 0.1 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.3 4.9 1.1 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.2 3.3 0.6 6.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell line enhanced" "Detected in many" "A549: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.7;eosinophil: 2.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Supported Supported Nucleoplasm Nucleoplasm "CAB011577: AB_727019, HPA002847: AB_1080107" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (1.41e-1)" "unprognostic (1.25e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" "unprognostic (9.63e-3)" "unprognostic (2.05e-3)" "unprognostic (1.66e-1)" "prognostic favourable (5.54e-4)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.99e-1)" 3.3 3.2 8.0 1.8 24.7 3.2 4.3 3.9 28.0 5.4 2.7 7.7 1.8 1.5 4.5 2.8 5.2 2.8 3.1 5.0 8.0 3.7 6.3 2.2 6.9 1.4 3.5 13.2 6.7 4.5 6.2 5.0 5.4 5.9 6.7 2.2 2.0 3.9 4.4 3.0 3.5 1.9 4.0 5.7 2.3 4.9 14.0 5.7 1.6 5.1 0.8 2.1 5.6 4.6 0.7 1.0 7.7 1.0 0.5 0.6 0.2 1.7 12.3 3.5 3.1 3.3 4.5 2.5 2.0 3.8 2.8 3.2 4.0 2.3 1.9 0.4 1.3 0.5 4.0 3.0 5.9 0.5 2.6 0.0 7.1 3.1 1.6 0.1 0.8 2.6 3.1 6.8 7.1 1.3 0.1 1.9 4.2 1.7 0.8 0.8 7.1 3.0 0.7 3.8 0.1 2.4 8.9 0.7 4.4 4.5 1.1 2.2 1.6 0.7 7.3 4.3 1.9 7.9 1.5 0.3 0.1 0.3 2.4 0.5 4.2 7.7 1.0 2.1 0.6 0.6 0.3 0.2 0.4 0.3 0.3 0.7 0.6 0.6 4.7 0.5 0.6 1.0 0.2 0.2 8.0 24.7 3.9 28.0 8.0 3.7 3.5 13.2 5.9 5.7 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: " "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavourable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavourable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.8 21.5 16.5 16.4 2.7 3.3 9.5 13.4 19.7 28.5 31.6 16.1 27.9 27.5 9.8 20.8 41.2 25.0 16.2 53.3 32.9 12.1 14.0 15.4 26.7 2.0 17.5 10.0 1.2 1.0 17.8 31.0 18.1 7.0 35.3 34.2 39.8 24.0 14.2 5.8 46.6 14.9 14.5 5.9 15.1 12.3 6.7 8.6 24.4 14.5 10.7 30.0 14.9 6.6 12.7 43.4 19.9 31.6 8.5 9.8 18.9 21.2 25.2 23.1 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 CDY1 CDY1A ENSG00000172288 "Chromodomain Y-linked 1" Q9Y6F8 Y 25622162-25624902 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY1B ENSG00000172352 "Chromodomain Y-linked 1B" Q9Y6F8 Y 24045229-24048019 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2A CDY2 ENSG00000182415 "Chromodomain Y-linked 2A" Q9Y6F7 Y 18025787-18028597 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "epididymis: 3.8;testis: 6.0" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2B CDY ENSG00000129873 "Chromodomain Y-linked 2B" Q9Y6F7 Y 17877410-17880220 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 355.0" "Group enriched" "Detected in some" 5 "Hep G2: 93.9;THP-1: 101.2" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "classical monocyte: 32.6;myeloid DC: 32.9" "Group enriched" "Detected in many" 20 "dendritic cells: 32.9;monocytes: 32.6" "Not detected" "Not detected" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 40000000 "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavourable (9.92e-4)" 27.1 1.7 0.3 0.5 0.4 2.1 24.7 0.4 0.6 3.1 8.9 0.5 1.5 2.4 7.3 2.1 4.5 6.7 57.7 8.1 0.3 0.0 0.7 355.0 19.8 2.3 0.3 0.6 3.9 1.3 0.0 0.8 1.1 0.6 11.2 1.0 3.8 3.9 4.0 1.6 1.4 3.5 10.2 0.7 4.4 7.0 1.0 0.3 0.4 1.7 2.3 1.5 8.2 16.1 0.2 32.9 0.2 32.6 0.1 1.6 12.1 0.0 0.6 0.0 0.0 14.1 0.0 0.4 0.0 0.0 0.0 0.0 6.5 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 93.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 101.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 20.3 0.0 0.0 32.6 0.1 1.3 1.8 0.5 0.2 0.2 1.6 32.9 0.2 0.2 0.4 0.2 0.1 0.4 1.7 0.1 12.1 0.3 0.4 0.4 0.6 0.3 0.0 0.3 0.6 0.6 0.3 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "esophagus: 46.7;intestine: 146.9;liver: 78.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018897 Enhanced Approved "Golgi apparatus,Cytosol" 7500000 "Golgi apparatus, Cytosol" "HPA018897: AB_1846558" "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favourable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 5.8 15.3 8.5 8.8 11.7 2.4 5.1 13.0 15.9 9.5 42.3 12.1 11.2 146.9 7.0 11.9 46.7 6.1 14.5 15.2 7.4 6.6 22.5 78.6 6.7 4.6 8.2 10.7 8.4 12.0 10.0 6.8 7.3 10.3 9.7 42.6 13.0 12.7 7.9 11.6 8.9 117.3 10.4 5.6 7.8 10.9 8.5 8.2 9.0 11.7 14.1 12.1 7.6 11.6 6.9 8.9 5.0 10.6 7.9 10.7 5.2 6.8 9.0 9.5 12.7 9.4 8.8 7.2 7.8 12.6 9.2 11.7 9.7 11.4 8.0 7.8 10.2 17.8 6.9 19.7 7.2 7.1 9.6 7.9 5.1 18.2 13.3 10.3 13.8 12.7 37.3 13.0 21.9 6.8 11.0 5.9 15.5 4.3 9.1 8.6 5.1 9.1 10.8 9.6 9.4 26.1 12.0 6.2 8.1 25.5 6.4 6.6 11.1 12.8 8.4 12.1 6.5 7.5 5.9 11.9 14.2 9.5 18.7 8.1 9.1 4.7 10.4 4.7 10.1 7.8 9.2 6.1 7.7 10.7 8.9 6.9 9.5 8.6 5.0 7.9 10.6 7.7 6.8 5.2 8.5 11.7 13.0 15.9 7.4 6.6 8.2 10.7 10.3 8.2 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961237-66975148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;liver: 26.7" "Cell line enhanced" "Detected in many" "AN3-CA: 8.9;Daudi: 9.8;U-937: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" 1200000 "Nuclear membrane, Endoplasmic reticulum" "HPA041008: , HPA041307: " "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favourable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.5 0.1 0.8 13.3 1.3 0.2 1.0 1.6 1.3 0.6 40.7 0.7 1.4 16.8 0.4 0.7 2.2 1.5 3.0 0.7 1.5 1.0 6.8 26.7 0.9 0.2 0.8 1.1 0.5 7.8 0.0 1.1 0.4 2.2 0.4 17.9 1.1 5.9 0.6 12.9 0.5 41.8 0.5 0.9 0.2 4.6 0.9 0.6 0.5 0.4 2.4 0.5 0.4 0.3 0.7 0.6 2.7 0.6 0.3 0.9 0.2 0.5 3.5 0.4 8.9 0.3 0.2 1.4 0.3 0.2 0.4 0.6 0.5 4.4 9.8 3.0 0.0 0.7 1.4 0.7 0.2 1.6 6.5 4.9 1.4 2.9 0.1 1.1 0.7 0.4 1.1 1.0 0.2 0.0 3.1 2.1 0.4 1.4 1.6 1.7 1.5 0.6 1.5 0.8 1.5 0.1 0.5 0.5 1.0 0.3 6.7 0.2 5.9 7.5 0.4 0.5 2.8 0.8 0.2 1.1 4.0 1.4 0.3 8.3 0.3 0.6 0.6 2.7 0.3 0.3 0.5 0.5 0.6 0.4 0.6 0.7 0.9 0.6 2.0 0.3 0.4 0.3 0.9 0.2 0.8 1.3 1.6 1.3 1.5 1.0 0.8 1.1 2.2 0.6 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 43.4" "Cell line enriched" "Detected in single" 44 "U-266/70: 13.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.1 0.1 0.7 0.1 0.6 0.0 0.1 0.1 0.8 0.1 0.1 0.1 3.6 0.0 0.1 43.4 0.1 0.0 1.4 0.1 0.8 0.5 0.1 6.6 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 1.2 0.3 0.1 1.2 0.1 0.1 1.8 0.1 0.0 1.7 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.8 0.8 0.5 1.4 0.1 0.1 0.1 CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53055033-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 42.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA042053: , HPA049420: " "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.34e-2)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (7.75e-3)" "unprognostic (2.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (5.09e-2)" "unprognostic (2.87e-1)" 18.0 12.6 14.5 12.5 17.3 30.3 15.7 49.3 19.6 18.5 13.8 6.6 17.4 8.0 14.2 15.0 14.4 13.5 11.6 12.2 15.9 8.2 16.8 12.3 12.3 9.2 16.0 12.3 18.8 12.9 28.1 39.9 12.3 15.1 13.7 11.5 8.9 17.8 15.3 17.1 14.4 11.1 11.6 20.1 11.6 13.4 7.0 18.7 15.6 17.7 11.2 9.4 13.9 15.1 16.4 42.9 23.7 12.7 12.1 8.8 1.7 5.7 6.7 15.0 12.2 11.2 16.4 2.6 10.6 7.8 5.6 2.5 3.7 5.2 7.7 6.9 8.7 7.0 7.8 5.5 7.9 2.7 5.8 10.9 6.4 2.3 7.8 15.1 9.1 11.3 5.6 8.2 10.4 8.3 12.7 2.6 7.0 2.2 7.5 3.4 5.4 5.1 26.5 18.0 3.3 3.4 5.4 6.4 7.1 9.4 3.1 7.8 3.4 7.0 16.0 10.6 5.4 3.9 7.1 8.0 5.5 13.5 7.5 6.5 10.4 23.7 9.2 8.9 5.7 7.6 8.8 12.5 3.9 6.2 5.4 16.4 3.1 4.4 3.0 12.1 12.7 42.9 1.9 1.7 14.5 17.3 49.3 19.6 15.9 8.2 16.0 12.3 15.1 18.7 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA044364: " "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favourable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavourable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavourable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 12.7 10.4 23.4 14.2 4.8 10.3 10.2 17.9 8.6 11.5 12.4 25.4 28.3 33.4 18.5 7.0 15.4 14.3 9.4 14.2 20.9 6.6 61.9 8.7 13.0 1.5 31.6 11.8 5.3 2.0 14.5 10.3 13.6 31.3 29.4 15.1 6.6 46.9 15.5 23.7 9.4 28.6 21.9 17.5 10.6 17.0 14.8 15.7 14.7 10.2 4.3 27.5 10.3 9.1 16.6 14.1 8.0 16.4 6.6 11.8 47.6 6.1 23.8 19.4 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.7 4.7 13.5 16.7 3.8 19.2 8.7 7.3 8.6 9.7 14.2 12.0 10.1 17.4 6.2 5.1 14.2 20.5 13.4 11.3 12.4 15.7 22.9 9.0 19.8 3.8 14.5 16.8 8.1 6.2 12.4 11.0 10.7 13.8 15.2 9.0 20.7 11.6 23.3 19.0 12.0 25.3 9.2 20.3 6.0 6.1 7.9 4.5 8.1 14.5 8.0 9.9 13.4 3.7 7.8 9.3 6.8 3.8 9.2 16.2 34.0 7.4 15.2 9.9 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: " "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-1)" "unprognostic (2.14e-3)" "unprognostic (6.56e-4)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "prognostic unfavourable (4.21e-9)" "unprognostic (5.03e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.11e-2)" 13.7 11.4 14.1 19.0 15.0 25.8 12.5 20.0 16.9 12.1 15.2 16.5 13.4 19.0 15.6 16.7 21.6 12.6 14.3 13.7 12.5 9.8 12.8 13.4 17.0 21.7 15.1 12.6 9.6 16.8 9.6 20.6 22.9 13.0 14.3 12.8 15.5 13.9 14.7 21.0 16.7 18.7 17.8 15.1 24.9 16.8 19.2 14.2 22.3 13.5 12.7 18.4 18.6 14.2 6.6 12.1 19.7 17.0 12.3 12.5 10.1 4.4 10.8 9.1 0.8 8.0 10.7 17.0 9.1 7.6 9.7 10.1 8.5 3.8 0.1 8.8 10.6 7.1 1.1 9.2 5.6 0.6 9.6 14.4 7.4 8.6 17.5 0.6 25.0 14.4 8.4 8.8 6.6 11.8 6.1 0.0 6.7 14.8 10.4 11.2 10.9 8.6 1.4 1.3 4.4 6.4 20.9 8.9 11.4 7.5 7.7 7.0 13.8 14.9 13.2 0.6 2.2 5.0 3.3 15.9 0.0 2.1 0.0 3.0 8.7 17.6 14.2 19.7 10.8 16.9 10.0 6.6 8.7 11.6 12.1 4.5 8.3 9.1 18.9 12.3 17.0 6.6 12.5 10.1 14.1 15.0 20.0 16.9 12.5 9.8 15.1 12.6 13.0 14.2 CHI3L1 "GP39, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186749 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 336.4" "Cell line enhanced" "Detected in some" "ASC diff: 39.8;ASC TERT1: 88.7;HSkMC: 78.7;THP-1: 125.5;U-138 MG: 37.2;U-87 MG: 37.1" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 490 "neutrophil: 81.3" "Lineage enriched" "Detected in single" 490 "granulocytes: 81.3" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 13 "olfactory region: 10.7" HPA077365 Approved "Golgi apparatus" "Secreted to blood" 25100000 230000000 "Golgi apparatus" "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 19.0 0.8 20.3 53.4 58.0 81.6 23.9 1.2 69.4 4.3 2.1 5.0 0.0 0.9 4.3 25.5 3.5 10.2 1.9 2.6 9.1 17.8 11.9 336.4 10.0 12.4 32.3 3.6 4.5 2.5 0.8 22.9 4.7 66.4 1.5 1.6 9.1 19.3 1.1 10.5 10.0 2.2 3.3 23.5 2.9 1.7 3.4 6.5 0.9 2.0 1.7 14.6 61.5 4.0 0.0 0.0 81.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 39.8 88.7 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 78.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.5 0.0 37.2 0.1 0.0 0.0 0.2 4.7 0.0 37.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.3 0.0 0.1 0.0 0.0 0.1 20.3 58.0 1.2 28.9 9.1 17.8 32.3 3.6 66.4 6.5 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase, acidic" Q9BZP6 1 111290862-111320566 "Enzymes, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 66.6" "Group enriched" "Detected in some" 4 "ASC diff: 5.9;HAP1: 3.1" "Cancer enhanced" "Detected in some" "lung cancer: 1.8;stomach cancer: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" HPA059193 Approved "Intracellular and membrane" "HPA059193: " "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.7 0.5 0.8 0.3 0.1 0.1 0.1 0.0 0.5 1.0 13.2 0.2 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 66.6 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 1.6 0.7 0.0 0.1 0.6 0.6 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.7 0.2 0.2 0.0 1.6 0.6 0.0 0.0 0.6 0.0 0.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 99.9;lymphoid tissue: 106.5" "Cell line enhanced" "Detected in some" "EFO-21: 2.7;LHCN-M2: 1.7;RH-30: 1.7;U-266/70: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 2.9;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.9;monocytes: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010575, HPA074844" Supported "Secreted to blood" 26410000 58000000 "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favourable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 99.9 0.2 0.2 0.4 0.3 26.7 5.5 0.1 0.3 5.9 0.6 0.5 0.1 0.0 2.5 0.2 0.3 0.1 0.2 0.6 0.2 0.1 0.1 0.4 22.1 106.5 0.4 0.1 1.4 1.1 0.0 0.2 0.4 0.5 0.6 0.5 0.3 0.3 0.1 0.1 0.3 0.7 0.2 9.4 4.3 0.1 0.1 0.1 2.3 0.9 0.2 0.5 0.1 0.3 0.5 0.2 2.9 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.2 0.0 0.0 0.1 0.2 0.0 1.7 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 2.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.9 0.0 1.1 0.2 0.0 1.3 0.2 0.3 0.1 0.3 0.2 0.1 0.4 0.1 0.5 0.1 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Conserved helix-loop-helix ubiquitous kinase" O15111 10 100188298-100229619 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favourable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 16.6 16.6 14.0 14.3 18.9 21.3 14.2 16.0 15.8 11.8 15.0 13.0 13.9 16.1 14.7 12.4 13.5 12.0 11.7 14.5 13.3 17.6 27.2 35.8 14.0 20.8 17.9 6.9 11.4 14.5 19.6 18.2 14.2 16.4 12.9 17.6 9.5 13.9 12.5 23.6 11.0 20.6 16.1 18.6 18.7 15.1 12.5 15.6 22.5 14.5 11.7 15.5 13.8 13.6 3.7 3.4 7.2 4.8 4.0 4.3 1.4 15.6 13.2 13.6 20.2 13.1 11.8 10.5 19.9 19.6 18.6 22.8 14.8 9.3 21.2 11.8 13.5 15.5 22.6 10.6 21.0 22.5 19.5 14.1 10.5 16.3 11.2 26.0 20.7 9.4 11.3 21.5 21.0 13.2 15.9 17.6 20.3 9.5 20.5 16.1 8.8 9.7 13.4 15.1 9.7 11.8 10.1 8.1 12.1 10.8 8.4 17.3 16.7 15.9 13.9 11.7 13.2 12.7 22.6 20.8 18.7 20.7 12.8 21.2 9.2 2.6 3.0 5.1 2.4 4.8 4.0 3.7 3.0 4.3 3.4 2.1 3.3 4.2 7.2 4.0 3.2 2.1 2.8 1.4 14.0 18.9 16.0 15.8 13.3 17.6 17.9 6.9 16.4 15.6 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685790-119877291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;brain: 35.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol Cytosol "HPA019082: AB_1846803, HPA048812: , HPA075506: " "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 1.4 4.4 14.7 3.3 14.0 15.3 1.6 12.7 35.0 1.6 4.6 2.9 0.0 4.0 1.3 1.5 3.2 0.9 1.6 1.0 9.8 5.7 5.7 1.4 3.0 3.4 3.2 21.9 0.7 0.7 1.2 2.9 2.6 7.4 1.0 5.3 0.6 1.3 1.0 1.3 5.1 3.5 2.6 5.0 5.6 3.5 8.3 9.5 5.9 1.5 0.1 4.9 1.7 1.7 0.4 0.0 0.0 0.1 0.0 1.2 0.8 15.0 13.5 11.9 11.2 1.1 3.3 7.0 11.5 9.6 12.1 9.1 8.6 6.2 10.8 6.2 8.9 9.4 8.1 6.7 16.7 7.7 5.9 13.7 8.7 5.3 0.1 7.2 12.6 0.7 0.7 14.4 8.9 9.2 8.7 9.2 11.3 7.5 13.0 11.0 6.4 9.1 11.9 21.6 3.6 2.4 6.6 8.5 4.7 19.1 3.7 9.1 13.5 5.2 7.0 15.1 13.9 10.3 12.5 6.3 7.0 7.4 10.0 7.9 23.3 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 14.7 14.0 12.7 35.0 9.8 5.7 3.2 21.9 7.4 9.5 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: " "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favourable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.1 6.1 10.3 3.1 11.7 12.9 8.1 8.8 12.6 9.0 12.0 11.4 5.3 2.8 6.0 5.5 8.8 13.0 4.1 18.5 12.4 11.4 8.3 15.5 14.1 7.0 8.7 14.2 5.9 18.6 11.3 19.9 5.2 10.0 36.8 12.8 5.5 10.2 26.4 6.5 14.0 10.4 12.2 14.6 6.2 5.3 10.4 8.2 7.7 2.9 12.8 2.4 6.0 8.0 10.1 6.9 9.7 9.7 21.7 9.0 6.5 6.5 7.1 6.8 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA055366: , HPA059507: " "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavourable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favourable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 6.0 5.2 18.9 5.8 9.5 5.1 16.1 5.4 6.6 4.2 4.2 5.5 4.3 13.1 7.5 3.7 8.7 9.4 7.0 4.0 9.5 7.4 10.4 5.4 7.0 8.2 12.9 10.5 4.1 6.4 6.1 12.3 7.3 14.6 9.1 6.3 10.4 8.8 7.7 12.3 7.4 9.8 11.4 14.1 10.6 13.5 9.0 12.8 2.0 6.5 5.0 9.9 15.9 4.8 2.6 6.9 4.7 4.5 17.4 14.8 11.9 5.1 9.3 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavourable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavourable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.5 14.8 15.3 24.2 21.9 26.9 19.2 14.8 20.4 11.3 13.6 15.8 35.0 14.7 14.3 28.9 19.1 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.3 28.7 24.0 23.9 12.1 14.9 12.7 15.8 19.8 22.7 12.0 10.0 16.1 9.0 13.3 17.0 16.2 10.6 12.4 12.2 13.6 13.5 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.4 19.6 16.7 11.4 33.0 16.3 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" "Actin filaments" "HPA043746: " "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.8 6.3 5.9 8.5 17.6 14.8 9.7 6.7 7.6 4.0 7.4 6.7 5.5 3.9 5.4 2.8 9.1 7.5 5.4 6.6 14.1 5.9 1.5 11.9 8.2 6.6 3.1 5.0 6.7 7.9 6.4 8.7 2.7 3.5 11.7 5.1 2.8 4.0 11.4 3.0 3.9 4.0 5.2 5.7 4.0 2.1 6.6 4.4 7.5 4.1 6.9 4.3 6.6 5.6 8.2 3.0 4.2 7.1 7.7 2.9 3.0 5.9 7.6 4.2 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55547138 "Enzymes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 9.3 9.2 7.8 5.8 11.7 1.7 8.4 16.2 14.3 12.5 9.5 5.2 9.2 7.1 10.5 8.4 13.9 8.1 6.7 10.5 7.9 7.9 12.4 9.1 8.2 9.4 7.0 9.8 11.7 8.6 18.7 21.9 8.5 8.4 9.7 8.4 5.6 8.2 9.2 16.1 9.4 12.6 13.8 8.3 9.1 9.6 18.5 5.0 4.0 14.7 5.9 5.2 8.4 17.1 2.5 3.6 0.6 3.0 2.9 4.7 1.4 13.4 5.9 5.3 8.3 8.0 8.1 2.6 13.9 11.4 9.7 9.0 3.7 10.7 3.6 7.2 16.1 11.3 6.8 10.8 16.5 4.4 2.4 2.9 6.2 4.6 7.1 4.7 3.4 4.7 10.7 13.4 13.2 9.1 6.6 7.4 14.6 7.4 2.6 2.6 3.8 6.8 1.7 6.1 2.4 7.5 7.3 5.2 4.7 10.0 12.4 6.3 4.2 2.6 12.5 13.2 14.1 4.3 18.7 6.7 4.8 2.3 11.7 4.2 10.4 0.0 3.0 0.6 2.8 3.0 4.7 1.4 3.2 2.5 3.6 2.5 1.9 2.4 0.6 2.9 2.7 2.1 3.1 1.4 7.8 11.7 16.2 14.3 7.9 7.9 7.0 9.8 8.4 5.0 CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1551 "pancreas: 4260.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.6;HDLM-2: 1.3;T-47d: 3.3;U-2 OS: 3.0;U-266/84: 2.4" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA010512 Enhanced "Secreted to digestive system" 1100000 "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 4260.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.4 2.7 0.4 1.3 1.1 0.1 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 3.0 0.0 1.0 0.0 2.4 1.0 0.0 0.9 0.0 0.5 0.4 1.3 0.1 0.2 0.0 0.3 1.1 0.1 0.4 0.5 0.3 0.0 2.7 1.3 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 1.6;BEWO: 1.5;HL-60: 1.7;TIME: 1.5;U-937: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced "Secreted to blood" 3000000 "CAB000363: AB_2083616, HPA052634: " "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.9 1.1 1.1 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.8 0.0 0.8 1.5 0.0 0.3 0.3 0.3 0.9 1.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029954: AB_10670558, HPA029979: AB_10671363, HPA029980: AB_10671094" "unprognostic (1.33e-1)" "unprognostic (2.12e-2)" "unprognostic (6.43e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.00e-1)" "unprognostic (3.72e-1)" "unprognostic (1.68e-2)" "unprognostic (6.43e-3)" "unprognostic (2.95e-2)" "unprognostic (9.17e-2)" "unprognostic (5.24e-3)" "unprognostic (1.50e-3)" "unprognostic (3.00e-3)" "unprognostic (3.27e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" 14.4 17.4 23.1 17.3 17.7 22.4 14.6 25.0 25.0 14.5 18.0 15.5 21.3 15.0 19.5 19.4 12.6 16.9 15.0 18.8 17.6 16.1 13.9 16.6 15.2 19.2 16.0 22.7 22.6 18.4 24.4 20.2 20.6 16.9 16.3 13.1 17.1 17.6 17.9 28.9 16.6 16.5 17.6 12.5 21.7 15.9 63.9 17.8 18.4 15.7 14.1 20.7 16.2 14.8 11.1 9.8 8.1 13.2 9.7 11.5 7.8 6.9 6.6 9.5 15.5 10.8 9.9 11.5 8.3 11.5 21.1 23.7 9.9 4.6 14.4 9.4 12.2 7.8 12.1 8.6 16.2 9.9 10.7 7.9 7.7 11.0 8.3 11.4 5.4 8.5 6.4 11.6 8.3 9.8 17.6 10.6 11.0 11.3 14.4 10.2 4.8 6.3 11.5 11.3 8.2 6.8 8.4 10.5 7.9 9.3 7.2 11.9 12.2 8.8 9.0 12.7 9.5 5.0 9.3 12.1 6.3 76.3 5.0 12.0 13.9 8.1 10.2 6.4 10.1 13.2 8.5 11.1 8.9 10.7 9.8 8.1 9.9 8.0 6.6 9.7 9.9 8.2 11.5 7.8 23.1 17.7 25.0 25.0 17.6 16.1 16.0 22.7 16.9 17.8 CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510127 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved "HPA005737: AB_1078544" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.64e-2)" "prognostic unfavourable (1.19e-4)" "unprognostic (2.82e-2)" "unprognostic (4.18e-2)" "prognostic favourable (1.61e-4)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "prognostic favourable (7.67e-6)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.33e-2)" 19.4 14.3 19.8 12.0 23.3 11.1 13.8 31.6 24.6 18.7 15.0 21.9 7.0 11.3 21.1 15.2 15.8 16.7 13.8 18.7 19.2 18.0 16.0 16.0 13.6 14.4 18.5 15.1 24.7 14.1 22.6 28.6 16.1 21.1 15.3 13.4 16.4 16.8 15.6 35.0 15.6 12.3 17.1 22.6 13.7 12.3 25.8 18.5 18.5 21.1 12.3 18.1 16.2 15.7 12.0 10.0 21.5 12.7 16.7 15.5 9.1 13.5 12.9 13.2 17.6 22.0 17.5 9.6 15.3 16.7 13.1 16.3 11.1 14.0 13.6 13.3 13.9 13.0 16.7 11.6 18.8 15.3 12.8 11.2 11.1 9.8 12.3 12.5 13.4 13.4 14.8 16.7 10.5 13.4 19.5 10.9 19.1 17.0 17.2 20.5 17.3 10.9 11.2 13.0 14.7 15.4 12.6 14.0 16.5 17.8 20.1 11.1 12.4 14.3 18.0 15.9 9.5 14.7 16.5 16.8 15.7 19.4 16.0 14.8 21.1 21.5 11.5 14.9 14.1 11.5 15.5 11.0 12.0 11.7 10.0 12.0 13.1 12.1 10.7 16.7 12.7 8.0 10.1 9.1 19.8 23.3 31.6 24.6 19.2 18.0 18.5 15.1 21.1 18.5 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966741-41977731 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 211.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 49.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Enhanced Nucleoplasm,Cytosol 730000 Nucleoplasm Cytosol "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 9.1 8.9 51.4 9.5 72.8 6.7 8.1 13.4 125.3 10.3 7.5 211.7 2.3 7.1 8.0 12.7 15.0 9.3 10.8 7.6 78.4 40.7 14.7 9.6 6.7 10.5 86.7 49.0 11.2 9.2 5.8 4.4 7.8 66.7 11.7 6.4 3.6 15.1 13.2 7.6 11.1 6.4 10.1 160.2 7.1 7.4 4.6 63.5 2.1 7.2 2.2 11.2 9.8 5.7 9.9 49.1 7.3 13.1 7.3 7.5 9.1 13.7 23.5 22.3 27.5 19.1 18.0 9.6 17.2 26.5 44.8 50.6 18.4 12.6 14.6 13.9 22.4 23.7 15.0 11.4 15.6 14.5 19.0 14.2 16.2 31.9 20.6 13.8 12.9 29.7 8.2 24.5 6.0 20.4 10.0 12.0 15.6 8.7 35.4 12.5 5.2 16.8 22.1 32.8 14.2 11.9 14.1 13.1 17.7 21.8 32.9 38.3 14.7 20.7 20.4 17.5 19.2 23.7 20.3 13.5 15.3 11.7 17.3 10.7 68.2 4.9 12.1 7.3 7.5 13.1 5.9 9.9 6.5 6.0 11.1 7.0 5.9 6.9 2.6 7.3 10.3 49.1 7.2 9.1 51.4 72.8 13.4 93.8 78.4 40.7 86.7 49.0 66.7 63.5 COL4A3BP "CERT, GPBP, STARD11" ENSG00000113163 "Collagen type IV alpha 3 binding protein" Q9Y5P4 5 75356345-75512138 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 51.1;WM-115: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Uncertain Enhanced "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: " "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favourable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 30.0 25.5 16.5 17.1 21.9 17.9 21.4 34.4 21.2 26.9 19.9 14.9 21.5 13.5 20.5 11.6 21.9 17.1 17.4 14.9 15.2 16.3 21.1 22.7 19.6 13.4 22.5 12.4 17.9 12.4 24.6 25.9 17.8 18.2 19.0 14.6 14.8 17.5 16.1 33.4 14.2 19.3 18.9 16.6 17.2 17.0 21.3 20.7 17.8 37.4 14.3 15.9 21.8 19.1 6.4 9.8 20.9 16.6 5.1 8.8 5.7 16.3 8.5 8.2 7.1 51.1 14.3 10.9 9.2 11.4 7.1 9.5 12.7 9.4 7.9 20.0 9.8 10.0 12.4 12.7 10.9 9.7 5.8 6.6 9.3 6.7 13.0 6.5 7.6 10.7 9.0 8.3 9.5 8.2 11.9 12.0 9.3 8.6 7.7 4.9 10.5 6.3 6.6 10.8 7.3 11.6 19.9 6.3 6.3 11.6 8.2 11.4 7.9 11.2 11.1 4.8 5.8 8.6 7.5 11.2 14.6 9.3 8.4 11.2 44.2 5.0 13.9 10.6 6.0 15.6 5.6 6.0 6.2 5.6 9.8 6.4 5.9 5.8 20.9 5.1 16.6 5.7 8.8 5.7 16.5 21.9 34.4 21.2 15.2 16.3 22.5 12.4 18.2 20.7 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941607-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.3" "Cell line enhanced" "Detected in many" "MCF7: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Supported "Endoplasmic reticulum,Vesicles" 560000 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favourable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favourable (5.67e-4)" "prognostic unfavourable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 18.6 49.0 29.4 14.3 28.8 24.3 27.8 19.6 32.9 22.4 23.4 42.4 36.1 21.0 19.8 33.8 58.1 19.4 36.8 28.1 28.9 22.3 31.1 139.3 30.9 17.0 29.0 18.4 36.3 27.2 14.1 12.7 59.0 23.3 25.7 8.9 24.9 67.3 30.9 21.5 27.7 28.6 15.5 41.0 17.8 24.8 18.2 23.7 11.5 19.2 44.0 32.0 36.3 28.0 11.2 55.1 10.9 60.0 12.9 15.6 28.0 19.0 19.6 2.2 19.4 22.1 19.7 0.8 21.6 27.3 18.5 21.3 16.6 22.2 7.7 9.6 30.9 26.1 3.7 23.2 4.9 16.6 24.7 13.7 10.5 38.7 41.3 22.8 5.5 25.0 28.7 16.1 16.0 17.4 55.4 16.4 15.0 118.0 8.9 41.0 4.8 6.6 13.5 19.4 10.6 19.6 60.5 9.5 8.3 7.2 61.3 17.8 13.2 64.3 20.8 33.2 12.7 10.9 16.2 6.0 2.5 6.3 35.8 30.9 22.8 10.2 60.0 10.9 15.6 39.9 12.8 11.2 10.8 12.6 47.7 10.7 9.6 10.6 2.4 12.9 26.6 55.1 13.3 28.0 29.4 28.8 19.6 32.9 28.9 22.3 29.0 18.4 23.3 23.7 COP1 "FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1, E3 ubiquitin ligase" Q8NHY2 1 175944831-176207493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavourable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 22.4 15.8 14.8 20.1 16.7 19.1 19.3 24.6 19.7 21.4 23.9 15.3 17.7 16.1 23.5 16.5 22.3 14.9 15.5 14.5 12.8 11.6 17.2 22.9 17.8 24.1 13.1 11.3 14.4 20.8 15.6 24.5 17.2 15.7 15.4 26.1 18.1 20.2 21.4 19.2 25.4 22.1 19.7 10.9 27.1 17.5 23.4 15.0 39.3 18.3 15.8 25.0 22.6 17.6 1.5 2.0 13.7 3.4 0.5 2.7 1.0 14.1 7.6 12.4 6.7 12.5 12.8 23.5 11.0 13.5 11.8 11.2 12.9 15.0 29.0 10.8 12.5 13.4 11.4 16.7 10.6 9.0 7.0 12.3 9.4 12.7 13.2 22.1 14.3 11.3 14.0 11.5 14.7 16.7 17.9 11.4 14.0 17.7 13.0 11.7 21.3 0.8 11.3 10.8 16.9 16.2 43.8 10.0 17.6 12.9 20.6 14.0 14.6 29.6 16.0 10.0 7.0 13.4 9.4 14.7 25.1 26.4 8.4 13.1 11.5 6.1 2.7 10.1 1.8 3.4 1.4 1.4 2.1 1.4 2.0 1.5 2.7 2.0 13.7 0.5 3.1 1.1 1.5 1.0 14.8 16.7 24.6 19.7 12.8 11.6 13.1 11.3 15.7 15.0 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3231 "pancreas: 3541.6" "Cell line enriched" "Detected in some" 5 "AN3-CA: 15.8" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" 17000000 "CAB025197: , HPA021836: AB_1846005, HPA052215: " "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.0 3541.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.3 0.0 1.9 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266827-130289798 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 529 "pancreas: 1357.9" "Cell line enhanced" "Detected in some" "AN3-CA: 4.4;CACO-2: 7.3;RH-30: 6.1;SCLC-21H: 3.3" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" 1500000 "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 1357.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 0.1 2.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 4.4 0.0 0.1 0.0 0.0 0.0 0.7 0.0 7.3 0.0 0.0 1.0 0.0 0.0 1.4 0.0 0.1 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.0 6.1 0.1 0.1 0.6 3.3 0.0 0.2 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.8 0.6 0.0 0.7 0.2 0.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865256-148897196 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.7" "Cell line enriched" "Detected in some" 43 "HEL: 79.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1118 "basophil: 111.7" "Lineage enriched" "Detected in single" 1118 "granulocytes: 111.7" "Low region specificity" "Detected in single" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 12.4 0.6 0.4 12.0 0.4 5.6 6.2 0.4 0.5 25.4 14.1 0.8 4.4 7.1 14.1 21.2 16.5 3.7 50.9 4.5 0.4 0.2 5.8 2.8 37.3 15.2 0.4 0.4 2.0 7.2 0.7 0.8 1.3 0.5 37.3 16.4 8.5 8.8 5.8 1.4 12.7 20.2 24.3 0.4 1.0 13.7 7.1 0.4 3.6 1.4 9.9 7.1 14.0 8.9 0.0 0.0 111.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 79.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 111.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.5 0.4 CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "blood: 25.2;testis: 30.4" "Cell line enhanced" "Detected in some" "RH-30: 10.9;RT4: 4.9;U-266/84: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 8.0;naive CD8 T-cell: 20.3;T-reg: 25.2" "Lineage enriched" "Detected in single" 114 "T-cells: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 1.6 0.1 0.1 0.1 0.4 0.0 1.0 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.4 0.1 0.1 1.6 0.0 30.4 0.1 0.1 0.1 0.1 0.7 0.8 0.1 0.0 0.0 0.2 0.0 0.0 25.2 3.1 0.8 0.0 0.1 0.6 0.0 0.0 0.0 0.4 3.2 0.2 0.4 2.4 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.0 1.8 0.7 0.7 1.2 0.5 0.0 0.0 0.0 1.1 0.0 1.2 0.0 0.0 1.6 0.1 0.0 0.4 0.0 0.8 0.0 0.0 10.9 0.3 1.4 4.9 1.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 8.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 8.0 4.1 0.0 0.0 2.1 20.3 0.0 0.0 0.0 0.0 25.2 3.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746385 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.2;prostate: 10.6;retina: 13.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.0;CACO-2: 6.2;EFO-21: 3.5;Hep G2: 9.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "olfactory region: 15.5" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 9.8 0.1 0.2 0.2 0.1 0.1 9.4 16.2 0.7 0.8 0.2 8.3 1.7 3.7 0.2 0.3 0.1 0.2 0.1 0.3 0.1 0.7 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.3 0.3 10.6 7.2 13.0 0.1 0.7 0.1 0.2 1.3 3.4 0.7 0.3 0.5 1.3 0.0 0.0 0.2 1.5 0.6 4.1 5.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 3.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.3 0.0 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880726 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: " "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favourable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 18.5 10.9 17.2 22.8 17.5 37.0 17.4 42.6 18.8 20.1 17.2 16.8 17.1 9.9 25.1 15.2 14.1 18.9 21.3 14.5 17.1 8.7 11.1 12.3 16.9 14.4 20.5 12.0 31.6 23.4 24.3 13.0 13.3 15.8 18.4 11.6 14.6 14.9 16.7 28.2 20.4 16.4 17.0 13.6 17.4 14.7 29.1 20.2 29.6 19.5 13.8 16.1 19.0 29.9 4.7 2.3 10.6 3.8 2.0 2.7 1.1 5.5 14.3 18.6 8.2 11.4 11.3 9.6 8.0 13.5 13.9 13.5 12.9 10.5 15.4 9.6 15.3 10.8 21.4 6.6 15.8 26.0 8.6 12.1 13.2 8.2 12.6 12.1 17.4 10.0 6.7 15.4 18.6 10.4 13.7 21.1 7.5 19.1 8.0 5.8 15.2 5.9 37.8 14.7 11.8 5.4 7.5 15.5 10.2 13.7 13.5 8.1 12.0 11.9 16.1 17.0 16.9 8.7 7.3 9.9 10.6 29.9 3.4 7.3 11.9 2.9 1.7 1.3 2.7 2.2 1.4 4.7 1.3 2.0 1.0 3.3 1.4 1.7 10.6 2.0 3.8 2.3 1.3 1.1 17.2 17.5 42.6 18.8 17.1 8.7 20.5 12.0 15.8 20.2 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492197-149551552 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Supported Cytosol Cytosol "CAB016680: AB_1614518, HPA051334: " "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favourable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavourable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 33.5 35.8 26.0 26.9 35.2 71.0 40.2 32.0 39.3 33.8 38.2 28.2 40.5 23.2 41.0 29.4 66.1 31.8 36.0 45.7 24.4 26.1 24.0 30.1 37.5 27.3 28.0 29.8 31.7 23.9 46.9 30.9 28.7 38.0 38.1 31.4 25.5 38.5 39.3 51.4 48.4 31.8 45.8 33.9 23.6 34.2 28.6 24.1 38.6 32.0 53.1 41.1 45.0 40.0 28.6 40.6 47.4 39.6 34.2 41.9 40.8 36.1 24.1 40.7 38.5 42.0 51.5 43.5 51.6 49.1 40.2 42.4 47.0 49.0 19.3 57.1 54.8 37.0 28.7 69.5 61.6 27.9 17.3 26.1 28.0 21.6 37.8 40.8 42.0 42.1 72.1 45.2 72.8 46.3 22.0 29.1 45.3 22.6 37.5 16.5 21.4 58.8 28.0 32.2 21.9 28.0 63.0 31.4 28.2 38.3 51.4 62.8 48.2 35.6 45.9 47.4 24.9 31.4 49.1 27.0 34.5 29.7 44.2 29.7 57.2 47.4 36.6 35.4 29.0 38.7 33.1 28.6 36.7 32.9 40.6 23.4 39.9 34.0 31.1 34.2 39.6 24.2 41.9 40.8 26.0 35.2 32.0 39.3 24.4 26.1 28.0 29.8 38.0 24.1 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 10.5;testis: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 42 "granulocytes: 10.5" HPA051334 Uncertain Cytosol Cytosol "HPA051334: " "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.2 10.5 0.2 0.1 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 10.5 0.1 0.2 0.1 0.2 0.2 CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273731 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015410 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "CAB015410: AB_831049" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (7.04e-4)" "unprognostic (2.38e-2)" "unprognostic (3.43e-2)" "prognostic unfavourable (2.38e-6)" "unprognostic (8.05e-2)" "unprognostic (1.09e-1)" "unprognostic (5.00e-2)" "prognostic favourable (9.62e-5)" "unprognostic (2.23e-3)" "prognostic unfavourable (8.34e-4)" "unprognostic (3.54e-1)" "unprognostic (2.52e-1)" "unprognostic (5.52e-3)" "unprognostic (4.74e-2)" 30.1 36.3 30.8 25.9 30.8 21.0 26.3 36.3 42.8 30.9 33.0 27.7 32.9 32.6 37.9 29.8 31.3 38.0 34.9 28.5 26.2 26.9 32.0 33.5 30.1 25.8 27.2 27.8 31.4 42.8 34.2 35.9 32.8 30.3 35.3 19.3 28.4 38.0 37.7 52.3 26.7 42.3 34.1 21.4 36.4 32.5 48.3 24.6 29.2 33.0 31.8 33.7 31.4 26.1 6.4 11.4 29.6 12.1 8.7 7.6 7.1 21.3 25.4 14.5 19.9 19.1 20.4 29.1 31.4 19.8 22.5 21.1 20.8 18.4 19.5 24.8 22.3 20.7 13.6 31.8 18.2 16.5 32.9 24.2 20.2 22.3 55.5 19.9 18.5 30.9 22.6 15.3 22.8 32.8 27.2 10.4 21.2 24.9 25.5 20.8 15.5 40.0 22.0 17.9 17.3 23.7 33.5 17.9 32.3 37.5 31.3 35.1 22.4 26.1 34.5 32.4 29.1 28.1 23.8 22.7 11.0 20.9 26.0 17.1 23.5 4.7 11.0 14.6 7.6 12.1 7.4 6.4 5.9 7.3 11.4 5.6 5.0 5.3 29.6 8.7 11.1 5.5 5.2 7.1 30.8 30.8 36.3 42.8 26.2 26.9 27.2 27.8 30.3 24.6 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Low lineage specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavourable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavourable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 28.5 22.9 30.7 18.3 32.5 21.4 28.6 40.1 42.6 26.4 21.5 32.3 15.7 19.0 37.3 27.3 23.4 28.0 22.1 28.8 31.7 22.3 17.3 11.8 28.4 17.3 28.6 30.1 38.1 25.4 56.2 29.2 33.1 28.7 26.2 17.4 30.5 23.9 23.1 26.3 35.3 17.1 24.0 23.2 20.9 21.8 13.0 33.9 13.3 21.4 14.2 17.4 25.5 28.8 3.7 15.7 4.8 1.8 5.9 4.0 1.2 23.3 11.4 31.0 29.7 15.5 23.8 23.3 30.5 39.1 27.8 27.0 14.6 18.3 17.6 13.3 28.8 20.0 23.5 42.2 20.2 28.1 51.1 5.6 37.7 11.2 32.0 12.3 15.0 22.7 35.8 42.3 57.3 29.5 12.4 36.4 26.8 15.6 17.1 15.1 22.7 16.5 32.0 22.2 27.6 25.5 19.6 45.9 18.0 26.0 27.0 30.5 13.8 17.9 33.5 25.2 27.5 14.5 24.3 16.3 23.3 24.8 37.4 13.9 42.2 3.8 1.8 3.4 3.4 0.8 4.0 2.5 3.8 3.4 1.8 3.7 2.1 3.1 4.8 5.9 0.6 15.7 1.7 1.2 30.7 32.5 40.1 38.8 31.7 22.3 28.6 30.1 28.7 33.9 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165517-64356259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 7.2 7.8 10.2 11.9 15.1 11.6 8.7 12.2 10.6 8.7 7.4 7.6 11.6 7.0 11.1 9.9 15.7 10.8 7.8 5.6 8.9 7.6 8.6 6.0 8.4 9.6 6.6 4.7 8.5 8.8 10.4 16.1 7.2 7.2 6.8 7.9 10.1 8.2 14.5 6.5 10.4 6.8 11.1 5.3 8.2 6.8 41.3 7.3 11.8 11.5 5.6 11.2 8.3 10.6 4.1 4.1 8.8 5.1 5.3 8.0 2.4 5.1 10.7 7.8 10.1 6.7 9.1 7.1 6.3 6.5 10.7 9.7 8.5 10.0 8.0 3.4 9.9 11.7 20.3 12.7 12.6 15.2 5.2 7.4 8.6 5.7 7.7 13.8 8.9 8.1 16.9 10.9 15.7 11.7 9.0 8.4 9.6 7.0 7.0 4.3 7.2 5.6 11.8 9.7 6.4 8.6 20.4 12.5 7.6 8.3 5.0 7.3 8.7 5.4 12.6 9.8 11.7 7.7 7.7 9.7 18.6 6.8 9.1 10.2 6.0 0.9 3.6 5.6 5.7 5.1 8.0 3.6 5.1 4.1 2.7 4.1 5.1 4.7 8.8 5.3 4.3 4.1 3.9 2.4 10.2 15.1 12.2 10.6 8.9 7.6 6.6 4.7 7.2 7.3 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941149-1981338 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles Vesicles "HPA034868: AB_10671235, HPA056572: " "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 18.7 22.2 24.8 34.9 19.5 38.1 16.7 30.8 28.9 14.1 19.0 18.2 18.9 27.0 16.5 19.0 22.1 16.9 20.4 16.0 23.3 18.3 19.3 17.9 21.8 35.1 17.3 21.2 18.6 27.0 11.4 24.4 16.7 18.7 18.7 8.7 19.7 26.6 16.0 29.0 23.3 22.1 15.1 12.7 39.1 24.1 58.5 17.4 20.6 16.5 18.1 32.2 17.1 17.1 4.0 5.9 11.2 14.1 3.5 4.9 2.3 23.2 12.5 17.5 27.4 6.1 11.6 14.6 14.4 9.6 11.0 13.6 10.3 12.8 14.7 12.2 9.2 16.8 9.4 17.6 4.9 13.3 20.4 10.4 20.5 17.4 9.9 16.5 26.3 11.4 11.6 11.5 7.4 13.1 21.6 50.5 7.2 13.6 32.8 21.7 31.7 14.1 28.5 11.1 23.8 8.3 24.6 28.2 23.2 11.0 18.1 16.0 11.5 27.2 15.6 14.0 11.0 29.2 16.8 32.6 17.3 18.0 14.1 15.7 14.6 2.8 4.0 5.0 4.9 6.2 3.5 3.9 3.6 4.2 3.9 4.0 2.9 4.1 11.2 3.5 14.1 5.9 2.5 2.3 24.8 19.5 30.8 28.9 23.3 18.3 17.3 21.2 18.7 17.4 CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512099-123617045 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved "HPA027010: AB_10602803" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "prognostic favourable (9.90e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.92e-3)" "unprognostic (4.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.97e-3)" "unprognostic (4.38e-1)" 20.7 15.0 15.5 21.7 22.7 11.1 37.7 23.7 31.7 18.8 24.0 8.6 11.2 23.5 19.4 18.4 18.8 14.6 17.7 14.0 22.2 18.0 16.2 27.7 29.0 21.8 13.3 17.7 18.7 15.8 18.6 18.1 16.2 16.6 13.2 27.4 9.1 15.3 14.1 15.6 13.4 24.9 18.6 16.1 16.5 18.2 16.4 11.4 17.2 16.2 16.5 17.4 21.9 18.2 13.6 5.3 11.3 5.9 12.7 9.5 5.1 12.9 12.5 18.8 17.8 19.2 21.5 9.3 14.1 16.9 15.7 23.5 11.2 20.8 0.0 18.4 16.9 9.5 15.1 27.9 27.1 19.6 10.3 9.2 14.5 11.8 17.1 4.8 9.5 18.2 18.2 17.6 33.5 17.0 5.1 10.6 13.2 9.0 6.4 5.9 10.6 8.6 7.3 19.9 12.4 11.7 14.3 16.4 11.9 15.7 10.4 22.9 13.6 13.5 15.6 23.1 17.5 14.0 15.5 11.9 13.0 11.7 13.8 13.9 14.9 11.3 5.8 2.5 7.1 5.6 9.5 13.6 5.9 6.2 5.3 12.9 6.1 6.4 4.6 12.7 5.9 4.7 7.3 5.1 15.5 22.7 23.7 31.7 22.2 18.0 13.3 17.7 16.6 11.4 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: , HPA061698: " "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavourable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 21.5 26.7 23.2 20.6 31.3 16.7 24.1 26.3 32.8 22.2 26.1 28.2 19.5 21.9 24.3 15.7 31.9 23.3 17.7 29.2 21.8 21.9 24.5 23.1 18.6 21.9 21.3 22.6 24.9 27.5 27.7 24.6 23.1 29.4 20.7 24.2 19.6 23.8 22.4 58.8 27.0 22.5 23.3 21.3 21.8 26.5 51.6 23.2 30.3 22.4 22.4 25.7 26.2 22.8 19.8 25.4 23.3 27.3 18.7 19.4 15.7 43.6 39.0 35.9 22.1 13.8 24.0 23.3 25.6 25.9 29.7 33.1 39.2 28.6 39.0 16.4 21.0 33.9 39.5 38.3 42.4 13.6 14.3 52.7 10.4 37.9 23.6 45.8 11.7 22.0 40.6 27.3 76.2 32.0 51.7 25.6 27.1 14.4 55.0 16.3 51.5 26.8 32.7 31.5 31.7 25.6 27.6 37.7 30.0 21.9 42.2 38.9 28.1 18.0 30.1 31.6 27.1 20.4 37.9 26.6 62.8 38.4 15.8 27.5 31.8 23.3 19.7 22.2 16.1 27.3 19.4 19.8 15.7 15.5 25.4 18.9 16.0 15.0 12.1 18.7 25.2 21.1 16.4 15.7 23.2 31.3 26.3 32.8 21.8 21.9 21.3 22.6 29.4 23.2 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58197920 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavourable (1.40e-5)" "prognostic unfavourable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 22.8 14.5 15.2 15.2 14.2 14.8 33.5 11.1 17.0 20.4 22.2 12.6 15.1 11.7 19.0 21.4 20.2 15.8 18.7 19.7 12.8 11.5 16.2 21.1 20.0 28.7 10.8 13.9 23.9 28.1 34.3 14.4 29.1 11.6 22.0 15.0 12.9 15.6 15.2 25.4 50.5 18.0 18.8 11.2 26.6 21.1 69.1 10.2 44.3 25.9 12.0 18.5 28.9 33.8 8.9 8.0 8.7 14.1 12.8 14.5 11.7 18.5 20.8 16.1 19.2 22.8 32.3 28.5 14.4 22.1 28.6 18.1 39.0 15.8 33.8 20.2 20.1 21.8 29.0 25.9 36.4 11.1 15.8 18.6 14.0 34.8 35.1 29.9 19.1 31.6 38.8 21.6 38.6 29.9 37.3 9.9 17.3 12.9 29.5 24.8 25.9 24.2 40.2 32.9 17.8 21.2 20.6 13.7 15.5 34.4 16.1 27.4 10.1 25.1 24.5 19.6 23.3 15.4 19.1 22.6 18.6 48.0 17.4 20.7 18.2 8.7 14.1 7.4 11.9 12.4 13.5 8.9 14.2 11.6 8.0 7.8 14.3 14.5 0.7 12.8 10.8 7.6 10.7 11.7 15.2 14.2 11.1 17.0 12.8 11.5 10.8 13.9 11.6 10.2 CSNK2B "Ckb1, Ckb2" ENSG00000204435 "Casein kinase 2 beta" P67870 6 31665236-31670343 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004349, HPA005944, CAB013087, CAB016059" Approved "CAB004349: AB_626791, CAB013087: AB_2533571, CAB016059: AB_626792, HPA005944: AB_1847290" "unprognostic (1.61e-1)" "unprognostic (3.21e-2)" "unprognostic (8.88e-2)" "unprognostic (1.55e-3)" "unprognostic (9.51e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-3)" "unprognostic (1.60e-1)" "unprognostic (7.52e-2)" "unprognostic (1.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.06e-5)" "unprognostic (5.88e-2)" "unprognostic (1.72e-1)" "unprognostic (9.67e-2)" "unprognostic (3.72e-2)" 28.1 30.5 26.6 28.8 28.0 30.3 27.6 26.9 42.9 29.9 32.7 30.8 24.0 13.9 26.2 101.7 51.5 30.1 32.0 43.8 24.4 23.1 41.1 49.8 34.4 33.8 25.4 24.6 32.9 42.1 3.5 26.4 39.6 23.6 34.3 26.0 30.4 30.3 32.5 40.8 58.3 31.6 32.2 26.6 33.3 26.9 66.0 20.8 60.2 38.5 41.8 33.4 28.3 25.9 20.6 24.9 21.3 22.8 16.3 20.2 16.0 0.0 6.5 0.0 10.7 6.5 10.9 8.0 15.0 26.0 30.7 29.0 0.0 9.4 23.1 8.1 11.0 0.0 0.0 26.5 30.1 11.2 26.9 0.0 0.0 0.0 16.6 25.3 0.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.4 0.0 7.7 0.0 11.7 0.0 14.7 14.7 8.7 0.0 18.3 0.1 0.0 11.5 0.1 0.0 7.4 12.8 15.6 14.6 0.0 9.5 14.8 14.7 9.1 0.0 11.6 16.5 22.8 21.3 16.2 22.3 16.0 20.6 16.7 16.7 21.1 16.4 14.4 12.7 18.4 16.3 14.1 24.9 20.2 16.0 26.6 28.0 26.9 42.9 24.4 23.1 25.4 24.6 23.6 20.8 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679801-79756623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: " "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favourable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favourable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 10.6 8.2 6.2 12.8 9.5 21.8 9.5 7.5 12.2 7.9 12.0 14.4 5.3 13.4 11.9 9.3 11.4 9.8 10.0 6.6 6.8 5.7 8.9 13.4 10.2 14.4 12.3 5.1 7.7 13.4 4.6 7.9 10.6 9.1 9.1 6.2 8.4 10.6 8.3 12.1 20.9 13.8 8.2 6.8 15.3 12.2 27.2 10.6 26.2 9.4 8.8 14.8 11.4 8.9 0.7 1.5 6.4 1.0 2.4 2.0 0.5 8.0 9.0 5.0 7.2 4.0 3.4 16.7 5.4 4.0 5.0 4.9 5.9 5.1 10.3 2.5 3.5 9.9 4.3 5.7 2.1 9.5 7.7 5.3 4.5 8.0 5.9 23.4 13.2 5.6 5.4 5.3 2.5 6.0 6.5 5.3 1.9 7.2 15.7 18.4 7.9 12.1 12.2 6.6 12.4 3.7 8.4 7.8 8.1 6.4 6.4 8.6 5.2 13.8 8.1 8.6 12.5 3.4 5.8 4.4 16.5 10.2 7.3 11.8 6.0 0.0 1.0 6.4 1.3 0.9 1.1 0.7 1.0 2.0 1.5 0.4 1.3 0.7 2.7 2.4 0.9 0.2 0.3 0.5 6.2 9.5 7.5 12.2 6.8 5.7 12.3 5.1 9.1 10.6 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm Nucleoplasm "HPA062654: " "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 32.9 22.5 15.9 21.9 13.9 19.9 41.1 12.2 16.4 34.8 30.7 27.6 31.8 24.2 34.5 30.7 31.3 30.9 43.4 25.9 15.5 8.6 34.1 47.5 30.2 33.2 15.0 13.1 44.9 50.8 28.8 12.6 71.3 15.9 41.5 19.8 35.4 34.3 31.5 23.2 30.5 41.3 33.7 12.4 39.1 34.2 15.1 16.1 33.2 41.0 27.2 29.9 32.5 28.4 3.4 6.6 29.3 12.4 6.7 11.0 7.5 10.1 13.1 7.8 25.5 21.1 19.7 29.3 13.7 19.8 13.3 11.5 17.1 25.5 6.2 11.9 24.2 20.9 11.5 16.5 6.8 22.0 9.0 23.5 16.1 22.9 25.4 14.4 32.9 22.4 20.2 10.1 11.4 19.5 19.0 22.1 14.0 28.5 12.6 42.1 5.4 13.5 17.5 10.9 13.3 16.9 12.6 5.2 12.9 12.0 26.1 12.9 14.4 34.7 17.0 21.2 12.9 16.1 6.0 14.2 9.2 14.5 18.8 13.7 11.7 20.3 12.4 29.3 11.0 10.2 7.1 3.4 6.7 7.0 6.6 3.2 4.3 5.7 24.5 6.7 10.4 2.3 5.6 7.5 15.9 13.9 12.2 16.4 15.5 8.6 15.0 13.1 15.9 16.1 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846739 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA052607: " "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 44.5 43.6 28.2 31.6 34.8 17.6 39.6 57.1 33.4 49.0 48.4 36.7 47.7 24.4 50.4 32.9 38.0 41.9 37.7 34.6 31.2 16.5 32.8 32.6 51.3 31.3 37.1 19.9 52.5 53.9 33.7 25.4 42.9 31.0 40.5 38.6 29.3 45.8 60.9 48.8 39.9 36.1 44.1 25.7 38.1 43.1 21.0 40.9 62.9 40.1 32.8 33.9 46.1 63.0 7.3 9.3 18.7 9.7 8.2 11.5 7.1 10.8 4.7 22.6 14.4 20.4 35.2 7.5 11.7 22.3 11.7 10.4 6.0 17.7 13.3 13.5 25.0 8.7 9.4 11.4 12.3 4.5 4.0 18.4 7.2 4.8 19.0 8.3 10.7 33.6 12.2 10.6 9.0 18.2 9.6 23.6 5.8 5.0 8.9 5.0 11.5 6.0 11.9 165.7 17.4 9.1 15.8 4.2 9.4 16.4 9.4 14.1 17.1 14.6 14.6 10.4 11.4 11.7 4.1 7.0 7.5 16.0 11.7 7.7 8.0 11.5 9.7 14.7 6.9 9.0 8.2 7.3 9.9 8.0 9.3 6.5 11.5 8.7 18.7 8.2 7.7 7.7 6.4 7.1 28.2 34.8 57.1 33.4 31.2 16.5 37.1 19.9 31.0 40.9 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861960-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles 10000 Vesicles Nucleoplasm "HPA048325: " "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favourable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 12.8 6.3 11.1 7.8 12.4 5.6 22.0 30.2 14.1 15.5 19.9 8.0 25.7 9.3 14.5 18.3 16.8 12.2 37.2 18.9 13.1 5.9 26.7 13.3 19.0 4.9 7.8 9.9 13.7 10.2 8.3 9.4 20.6 6.9 17.5 20.3 15.6 45.5 22.4 12.5 34.8 11.2 21.3 8.1 11.3 19.7 8.1 8.3 2.9 10.0 13.9 6.9 19.6 21.7 0.0 0.2 1.1 0.5 0.0 0.5 5.6 15.5 6.8 2.8 8.8 11.0 15.9 20.9 10.7 13.5 7.4 8.8 9.8 12.8 0.0 6.6 13.2 13.0 6.9 20.3 6.0 0.0 5.4 9.5 7.2 22.1 10.1 0.0 2.3 8.2 49.9 7.8 9.4 10.4 3.0 0.0 12.3 4.9 3.9 0.0 11.5 1.0 4.3 5.4 0.1 23.8 10.4 2.3 7.4 5.9 10.6 11.9 10.2 2.6 8.2 5.4 7.5 10.0 6.7 0.2 0.0 0.0 6.0 5.3 9.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 1.1 0.0 0.0 0.0 0.0 5.6 11.1 12.4 30.2 14.1 13.1 5.9 7.8 9.9 6.9 8.3 CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated protein homolog" Q6UX04 5 64768930-65018763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Dwarfism, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: " "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavourable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" 15.6 16.4 22.0 14.9 30.4 21.7 16.4 30.1 25.6 16.5 17.5 13.8 14.0 11.8 19.4 15.7 17.3 14.9 13.8 22.1 20.6 19.9 17.5 12.1 12.8 17.0 22.3 20.7 23.3 10.9 21.4 28.8 17.5 26.2 18.6 18.7 11.4 13.3 16.0 24.0 13.8 15.9 24.7 23.3 15.0 13.9 19.6 23.6 22.5 17.2 18.2 18.6 18.6 20.0 15.1 14.6 8.6 11.5 17.0 15.9 9.0 15.2 10.2 18.3 33.9 15.7 19.2 20.5 16.0 13.4 18.0 18.9 17.0 19.4 22.6 28.1 16.6 9.7 19.2 29.0 32.8 18.8 15.7 17.0 17.2 14.1 24.1 17.7 11.5 12.8 22.3 22.6 28.8 19.0 16.5 14.9 17.8 15.1 24.6 16.1 14.8 12.3 22.9 24.7 23.5 17.1 13.3 21.8 9.6 19.5 8.0 18.1 17.4 26.1 15.7 10.6 18.7 16.9 25.5 11.7 15.1 22.2 19.8 31.2 18.7 8.6 11.5 7.9 12.8 11.3 15.5 15.1 14.2 15.9 14.6 11.9 15.4 15.9 2.5 17.0 8.5 12.0 15.1 9.0 22.0 30.4 30.1 25.6 20.6 19.9 22.3 20.7 26.2 23.6 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: " "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.1 2.9 3.3 3.7 5.3 7.7 3.0 13.6 19.9 14.2 8.4 2.4 4.3 10.6 4.9 13.2 3.6 3.9 8.2 21.1 46.4 6.0 5.3 5.1 1.9 10.6 5.2 24.9 8.4 6.7 17.1 17.9 5.7 2.2 9.2 19.8 1.3 5.1 7.6 3.5 4.8 4.6 6.8 10.1 4.6 3.2 4.3 3.3 11.5 3.9 3.3 3.9 6.6 6.4 24.3 5.5 8.5 5.5 24.3 23.1 11.8 17.8 5.9 5.1 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell line enhanced" "Detected in many" "HMC-1: 38.7;HUVEC TERT2: 21.9;RPTEC TERT1: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome Centrosome "CAB037302: AB_1078622, HPA040472: , HPA048436: " "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.2 8.8 6.1 0.2 0.1 14.0 1.2 1.7 7.2 8.1 2.6 0.1 0.1 1.8 0.3 17.0 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.8 0.0 38.7 0.5 2.9 1.3 0.5 21.9 6.6 3.7 6.0 0.5 2.6 0.0 9.9 0.0 0.7 7.8 0.0 20.0 18.2 4.0 4.5 0.0 1.8 7.7 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell line enhanced" "Detected in many" "ASC diff: 10.0;HaCaT: 8.3;HMC-1: 17.0;MCF7: 8.6" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA071581: " "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favourable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.6 1.4 10.0 0.4 0.1 1.9 6.0 1.0 1.1 0.8 1.4 0.2 0.6 6.0 8.3 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.0 1.0 7.2 0.3 0.2 0.6 0.4 0.1 0.7 8.6 0.0 0.3 0.6 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Approved Nucleoplasm Nucleoplasm "HPA028569: AB_10794319, HPA064809: " "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favourable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.5 20.3 12.7 16.0 9.5 10.8 19.6 35.3 28.5 28.9 19.1 37.4 7.7 14.2 17.3 30.9 20.4 12.4 20.0 10.5 20.7 20.6 5.7 24.9 21.4 30.3 13.7 21.5 24.5 25.0 26.1 15.1 23.9 18.0 24.7 17.5 16.6 13.5 10.3 19.7 16.3 17.0 18.8 13.2 17.4 20.1 20.1 14.0 23.7 28.7 20.2 20.6 10.8 44.6 37.1 16.8 33.2 44.0 27.6 22.6 16.4 29.6 14.4 19.8 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell line enhanced" "Detected in some" "ASC diff: 17.3;ASC TERT1: 16.4;fHDF/TERT166: 13.3;HAP1: 10.3;HSkMC: 15.1;NTERA-2: 21.4" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: , HPA015655: " "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 17.3 16.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 13.3 0.0 10.3 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 15.1 7.5 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 21.4 0.2 0.0 1.2 0.0 0.6 0.0 4.3 2.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.5 4.4 0.7 0.1 0.0 0.0 1.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell line enhanced" "Detected in many" "AF22: 18.2;BJ hTERT+: 19.0;fHDF/TERT166: 8.3" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favourable (3.25e-4)" "prognostic favourable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.2 2.8 0.0 0.9 0.3 8.2 19.0 2.7 0.6 0.1 0.0 0.0 0.3 8.3 0.0 2.6 0.0 3.4 3.7 1.6 0.0 4.7 0.0 3.9 0.5 0.5 0.5 0.0 1.6 0.2 0.9 0.0 0.0 1.9 0.1 0.3 0.0 0.3 1.0 0.0 2.1 0.7 0.0 0.8 7.0 6.6 3.4 2.5 0.8 0.0 0.0 1.6 2.5 1.0 1.6 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.6" "Cell line enhanced" "Detected in many" "SH-SY5Y: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006308 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" 140000 "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532" "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favourable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favourable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 4.3 14.3 43.9 5.8 44.9 0.7 6.6 14.4 37.2 7.7 22.1 20.7 4.3 21.1 6.0 33.8 4.9 18.4 12.2 6.4 29.5 24.1 61.6 39.9 11.8 1.1 24.9 37.0 3.4 13.8 13.0 7.2 3.1 13.8 13.1 21.4 4.1 8.5 6.2 13.8 2.8 19.9 7.4 8.1 4.1 15.6 9.3 11.0 0.0 14.1 1.0 1.2 6.0 3.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 18.7 2.3 6.6 1.2 11.1 9.4 0.8 22.1 13.4 7.9 8.4 26.6 5.0 0.0 9.2 25.0 5.4 23.9 4.6 10.1 0.0 9.2 0.0 6.3 9.2 4.0 17.0 1.0 7.8 0.4 6.6 4.2 12.5 0.0 1.9 20.2 1.5 0.9 0.0 7.9 6.9 0.0 15.5 0.2 33.7 14.0 18.7 36.3 2.9 16.8 2.7 9.1 1.3 24.4 6.9 5.6 1.7 15.4 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 43.9 44.9 14.4 37.2 29.5 24.1 24.9 37.0 13.8 11.0 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 10.6;ASC TERT1: 13.2;EFO-21: 16.9;fHDF/TERT166: 10.5;SK-MEL-30: 10.6;U-2 OS: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012509 Uncertain Supported "Centriolar satellite,Cytosol" 1800000 Cytosol "Centriolar satellite" "HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 24.3 7.8 12.5 11.1 10.3 5.5 22.7 3.1 7.8 32.1 17.0 7.9 12.9 2.6 34.6 22.0 18.4 18.1 26.7 20.7 11.8 10.8 16.9 12.9 37.4 16.5 10.6 6.6 22.5 4.3 3.0 6.2 13.7 13.1 19.8 5.4 13.0 18.1 13.2 6.8 15.1 22.3 27.1 18.9 21.4 11.4 7.3 9.9 14.1 35.4 17.1 8.9 16.3 23.4 2.9 5.5 8.0 2.7 2.3 0.5 0.3 0.4 6.6 0.2 1.4 10.6 13.2 0.7 0.6 0.3 0.4 0.1 4.3 0.7 0.2 16.9 10.5 0.8 0.0 6.2 0.0 0.1 8.9 0.5 0.5 0.1 0.3 0.9 0.0 8.5 0.1 0.8 0.1 0.1 0.2 2.2 0.0 3.6 0.5 2.5 0.1 0.2 0.3 0.5 0.0 7.5 0.7 0.4 0.9 0.3 0.0 10.6 0.7 0.9 1.1 0.8 12.6 0.2 0.1 2.7 9.2 2.5 7.3 1.5 0.2 8.0 0.8 7.7 0.5 2.6 0.3 2.9 0.2 0.3 1.5 2.5 0.1 0.1 1.3 2.3 2.7 5.5 0.4 0.3 12.5 10.3 3.1 7.8 11.8 10.8 10.6 6.6 13.1 9.9 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769717-45782552 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.6" "Cell line enhanced" "Detected in many" "RH-30: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favourable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 9.0 18.7 5.1 9.7 6.3 1.7 4.9 8.8 6.2 16.5 23.4 4.4 15.6 8.7 21.2 15.0 31.2 13.7 20.3 56.7 5.0 5.3 4.9 2.2 6.5 4.1 4.8 6.5 8.4 33.3 3.1 10.7 6.8 5.6 16.3 3.8 22.0 6.1 19.7 79.6 5.1 11.3 65.1 4.2 5.3 12.0 5.9 4.0 1.1 6.1 36.6 5.0 44.9 8.2 1.5 0.0 0.0 0.8 0.3 2.2 0.0 7.2 10.1 12.0 7.4 8.1 11.3 7.2 16.2 12.0 6.5 6.3 1.2 3.9 2.3 2.4 18.5 10.6 3.4 1.6 2.4 11.3 10.6 0.9 12.6 1.7 7.9 0.1 4.1 16.5 5.7 5.6 2.7 3.0 7.1 5.8 9.4 8.0 1.1 2.7 7.1 2.2 3.7 44.2 3.7 3.5 8.3 6.5 10.3 8.8 18.5 5.2 15.2 3.5 9.1 7.6 7.5 7.2 11.8 11.2 9.6 2.3 6.9 1.0 10.6 0.0 0.0 0.0 2.2 0.8 0.5 0.3 0.7 0.2 0.0 1.5 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.1 6.3 8.8 6.2 5.0 5.3 4.8 6.5 5.6 4.0 DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046439, HPA076234" Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA046439: , HPA076234: " "unprognostic (1.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (3.57e-2)" "unprognostic (8.59e-2)" "unprognostic (8.12e-2)" "unprognostic (1.37e-2)" "unprognostic (2.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.88e-1)" "unprognostic (9.00e-2)" 12.6 21.5 11.2 9.1 19.0 7.9 21.4 10.4 11.9 17.3 12.8 11.5 13.2 6.8 20.6 19.0 16.1 19.3 10.0 19.2 11.2 11.9 14.1 18.1 8.5 15.2 11.9 11.4 39.0 28.4 15.5 31.7 9.3 12.3 15.3 13.7 10.8 16.1 12.7 16.8 11.5 9.2 15.4 16.7 13.6 11.5 9.2 11.3 22.2 18.4 15.5 17.7 14.4 14.7 12.1 8.4 3.3 6.2 14.9 16.2 6.7 9.5 8.7 13.0 12.7 16.0 45.7 11.2 8.5 13.8 12.3 10.4 10.4 2.4 16.8 11.2 7.1 6.2 14.4 12.8 18.2 7.0 10.6 8.8 8.4 19.6 25.0 10.7 4.7 30.6 18.7 11.5 37.5 18.4 19.7 5.3 18.6 8.2 13.0 10.5 10.5 13.6 12.1 18.9 9.6 13.9 7.3 15.0 7.3 4.6 12.9 37.3 8.4 6.4 9.3 7.3 10.3 10.6 11.1 6.3 7.3 10.3 10.0 10.1 2.7 3.3 5.1 2.6 11.1 5.5 15.1 12.1 12.3 12.1 8.4 9.6 16.2 14.8 1.9 14.9 6.2 6.2 8.2 6.7 11.2 19.0 10.4 11.9 11.2 11.9 11.9 11.4 12.3 11.3 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211566 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Uncertain Uncertain "Nuclear speckles,Intermediate filaments" "Nuclear speckles, Intermediate filaments" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavourable (8.73e-5)" 6.4 9.2 13.8 4.4 13.3 19.6 8.2 20.4 16.4 8.4 6.5 6.8 4.2 3.3 10.5 7.4 6.7 9.2 5.4 5.7 10.7 9.0 9.3 2.5 7.3 5.4 8.1 11.8 14.0 5.9 22.0 11.0 7.1 12.2 7.2 4.6 9.2 6.2 8.8 14.6 14.0 4.8 8.8 11.0 7.0 5.3 11.5 9.2 7.1 8.4 3.6 5.3 7.6 6.4 3.5 3.1 9.8 3.5 4.8 5.1 1.6 6.8 4.5 4.8 5.8 7.0 11.9 3.4 8.6 8.6 9.0 6.2 2.0 3.8 5.1 2.6 14.5 4.9 5.2 5.5 9.2 2.4 5.7 9.2 5.9 2.1 6.3 2.6 4.9 7.0 8.4 9.2 8.8 6.6 11.9 3.4 7.1 4.7 2.0 2.3 5.2 5.4 1.8 8.7 4.4 6.0 4.3 2.7 5.2 7.3 7.6 24.1 5.6 3.4 6.5 5.6 5.7 8.5 5.7 3.5 2.5 3.0 6.6 3.6 20.1 9.8 3.5 6.0 4.6 2.5 4.3 2.7 3.4 3.8 3.1 3.5 5.1 3.7 5.1 4.8 1.8 2.3 2.0 1.6 13.8 13.3 20.4 16.4 10.7 9.0 8.1 11.8 12.2 9.2 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 43.1;hTCEpi: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA069577: " "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.4 1.7 2.3 37.5 22.0 2.9 34.9 10.2 23.5 9.5 5.9 2.5 0.7 10.2 24.5 0.9 1.6 8.6 11.0 19.1 4.6 0.4 11.9 2.5 43.1 0.2 0.8 21.0 75.3 10.6 17.3 7.3 1.7 13.7 15.1 2.5 1.1 1.0 1.5 1.6 40.5 3.2 6.3 16.7 1.1 7.4 3.1 9.4 16.1 1.2 1.3 0.4 19.2 16.7 8.3 16.2 2.6 2.8 1.6 0.6 14.8 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell line enhanced" "Detected in many" "HaCaT: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favourable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.0 2.6 0.2 0.1 18.8 9.7 0.2 4.0 10.6 6.7 5.2 0.1 1.6 4.7 1.4 10.4 41.5 0.9 3.9 5.8 12.0 0.5 8.1 1.1 0.7 4.4 3.6 5.5 13.5 2.9 7.2 7.3 0.2 0.8 1.6 6.4 0.1 0.7 2.7 0.6 0.2 0.4 11.5 0.3 2.3 3.7 15.5 1.2 0.5 0.5 17.2 0.9 2.1 1.4 3.4 0.9 5.1 4.9 2.8 2.0 2.5 5.3 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: " "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavourable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 19.6 16.1 15.1 15.1 17.9 29.5 21.4 31.8 21.5 23.1 16.8 16.4 16.2 16.3 29.9 19.8 38.7 37.4 15.2 15.2 17.2 13.9 19.3 16.5 17.2 21.5 12.7 15.8 26.4 14.9 11.6 28.2 19.1 14.0 18.2 16.8 16.5 22.3 20.3 16.2 27.9 19.7 18.9 13.4 21.5 15.4 19.7 13.8 28.7 16.8 16.2 29.3 20.4 27.3 29.9 20.9 42.6 19.1 28.0 37.6 29.2 19.0 8.3 8.9 9.4 16.2 20.3 16.0 14.0 18.4 18.3 18.7 11.9 14.5 24.8 9.1 15.1 13.4 11.0 28.2 17.7 17.1 11.5 15.2 6.3 18.1 17.0 17.1 14.3 16.4 34.3 16.3 22.7 20.2 16.1 14.6 20.2 10.5 16.4 18.2 14.4 11.4 6.6 24.0 22.3 14.8 15.9 13.3 7.2 13.0 15.5 16.5 8.2 9.1 11.4 13.1 16.1 15.0 16.5 15.6 12.3 32.8 12.1 17.4 12.7 24.7 19.1 42.6 26.8 16.9 34.6 29.9 31.7 31.6 20.9 28.1 33.9 31.8 29.1 28.0 16.9 15.9 37.6 29.2 15.1 17.9 31.8 21.5 17.2 13.9 12.7 15.8 14.0 13.8 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavourable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.0 17.0 18.6 12.5 9.9 10.8 17.6 14.4 18.8 22.2 17.2 24.1 15.8 10.9 15.0 17.5 13.0 14.4 17.7 21.7 14.2 12.8 9.8 15.5 15.6 21.1 20.8 9.8 14.6 19.4 19.3 34.8 15.4 17.3 12.0 15.9 16.8 12.1 23.6 29.7 24.7 17.9 18.2 17.9 12.5 22.2 11.9 25.3 12.2 20.5 23.8 17.8 24.0 10.7 19.2 17.9 14.9 30.6 20.3 16.8 26.1 11.9 21.1 18.9 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 75.2;testis: 18.6;tongue: 26.0" "Cell line enhanced" "Detected in some" "BEWO: 4.9;EFO-21: 5.7;Hep G2: 11.9;K-562: 4.6;LHCN-M2: 10.6;RH-30: 9.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "neutrophil: 3.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 3.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "unprognostic (1.79e-1)" "unprognostic (2.39e-2)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.66e-3)" "unprognostic (2.47e-3)" "unprognostic (8.63e-2)" "unprognostic (1.97e-1)" "unprognostic (2.63e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-1)" "unprognostic (2.22e-7)" "unprognostic (1.93e-2)" "unprognostic (1.54e-1)" "unprognostic (4.81e-1)" "unprognostic (2.09e-2)" 0.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.2 0.0 0.0 5.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.3 0.0 75.2 0.1 0.0 0.0 0.0 0.1 0.0 18.6 0.0 0.0 1.0 26.0 1.9 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.1 0.1 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 11.9 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 4.6 0.0 10.6 0.6 0.0 0.0 0.7 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.7;BJ hTERT+ SV40 Large T+ RasG12V: 12.5;HBF TERT88: 17.9;WM-115: 10.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavourable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.0 6.1 10.7 12.5 0.9 1.8 0.1 0.7 5.8 1.3 0.1 4.7 17.9 0.1 0.5 0.0 1.0 2.0 0.8 0.4 1.2 4.7 2.9 3.8 2.0 0.2 0.4 0.0 7.9 0.3 0.8 0.2 0.2 0.0 0.7 0.5 0.2 2.6 0.7 1.3 0.1 0.4 0.7 1.1 0.6 1.0 0.7 8.6 2.0 0.1 4.0 0.0 0.2 0.1 0.0 0.0 10.3 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.3;REH: 17.4;SH-SY5Y: 5.0;SK-MEL-30: 4.3;U-2 OS: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA076649: " "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favourable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.3 0.1 1.0 2.2 0.3 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.7 0.7 0.0 17.4 2.0 0.1 0.0 0.0 2.4 5.0 2.8 0.0 4.3 1.3 1.0 0.0 0.0 4.2 0.0 0.0 1.8 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 24.2;RT4: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favourable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.1 5.2 2.7 1.8 2.4 8.7 1.7 3.7 4.1 6.0 12.2 5.3 0.2 0.9 1.8 1.8 9.2 1.5 5.9 8.9 4.6 0.4 4.4 13.6 3.9 0.8 1.9 1.9 4.6 3.3 10.9 3.2 2.4 7.5 0.3 6.0 1.0 0.6 24.2 1.3 1.2 1.7 5.0 2.6 22.0 7.9 7.6 6.6 8.9 4.4 3.4 1.5 2.8 1.9 5.5 1.2 1.9 5.3 6.1 0.9 2.5 1.8 2.6 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Nucleoplasm "CAB034070: AB_2094867, HPA051349: " "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.2 5.7 2.6 6.4 6.4 12.9 2.5 5.0 5.7 5.1 5.5 3.1 5.6 3.5 3.5 6.2 3.9 1.6 4.0 5.7 9.8 6.3 1.7 2.0 2.0 2.8 7.3 5.8 3.6 5.7 8.5 3.1 15.5 1.8 3.2 5.5 4.5 4.0 1.8 1.0 3.5 2.9 1.7 1.3 6.1 3.7 6.6 3.8 5.2 2.1 3.7 4.6 2.1 11.2 10.5 5.7 2.7 2.9 2.3 2.6 1.7 11.8 1.3 5.2 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.8 1.4 3.9 2.2 0.0 1.1 1.8 4.5 1.6 2.2 2.9 1.0 5.9 1.2 0.3 5.7 0.8 3.5 5.7 3.1 10.5 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.6 3.1 1.6 2.7 1.0 4.9 2.5 2.4 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 3.9 1.6 2.8 0.8 1.0 2.0 2.4 2.1 1.6 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;Karpas-707: 17.4;NB-4: 14.4;RT4: 17.3;SCLC-21H: 15.5;U-698: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" "Nuclear membrane" Nucleoplasm "HPA071920: " "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavourable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.2 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.5 2.1 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 17.4 0.1 2.6 12.4 14.4 3.4 5.4 0.0 0.2 12.1 0.1 17.3 15.5 0.8 0.7 0.2 2.8 1.0 7.2 0.0 0.0 4.1 0.0 0.8 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844004-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 15.9" "Group enriched" "Detected in some" 5 "CACO-2: 1.7;K-562: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 70.3;U-266/70: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.5 2.2 4.7 7.0 5.4 6.1 6.2 2.6 2.1 2.3 2.8 2.3 4.0 7.5 6.4 2.7 2.5 5.9 4.9 1.7 17.9 6.8 5.1 1.7 6.4 2.8 1.8 6.7 4.5 14.8 1.7 3.1 6.7 4.7 25.2 1.9 2.1 2.6 6.5 2.8 5.1 5.3 3.2 70.3 4.4 1.5 8.1 3.2 2.2 0.9 7.7 4.7 2.3 9.1 2.1 2.8 2.1 1.6 35.8 25.2 10.4 0.8 5.0 4.7 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell line enhanced" "Detected in many" "HSkMC: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm Nucleoplasm "HPA028211: , HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavourable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.0 0.1 5.0 4.1 5.9 4.6 5.3 14.0 0.0 29.9 5.4 0.5 3.4 4.5 3.2 3.0 1.5 16.8 4.7 0.0 19.2 10.1 12.9 46.6 12.2 3.8 13.8 22.4 7.6 6.1 8.2 22.1 1.0 0.4 22.7 18.8 0.0 0.0 5.7 7.1 2.1 5.7 12.7 9.0 19.9 23.2 12.8 15.9 16.4 4.9 0.2 0.6 0.0 4.3 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 45.1" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 45.1 10.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 DUSP27 ENSG00000198842 "Dual specificity phosphatase 27, atypical" Q5VZP5 1 167094045-167129165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "heart muscle: 46.8;skeletal muscle: 64.8;tongue: 18.2" "Cell line enriched" "Detected in some" 10 "RH-30: 17.7" "Group enriched" "Detected in many" 6 "colorectal cancer: 12.8;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA012912 Approved Nucleoplasm Nucleoplasm "HPA012912: " "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.44e-3)" "unprognostic (1.22e-1)" "unprognostic (2.10e-3)" "unprognostic (4.65e-2)" "unprognostic (1.53e-1)" "unprognostic (8.19e-2)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.72e-1)" "unprognostic (7.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 2.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.1 46.8 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.0 0.9 0.0 64.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 18.2 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favourable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.5 1.4 0.7 2.3 1.9 1.1 1.5 1.1 0.9 4.4 2.7 1.0 1.2 4.9 1.7 0.6 1.6 3.3 6.2 3.8 3.3 2.4 1.0 2.5 6.6 1.6 1.7 1.0 1.3 0.7 2.7 3.2 1.3 1.8 3.1 4.0 1.4 1.4 3.8 4.7 3.6 1.1 2.9 4.8 2.7 1.8 1.9 2.1 2.3 4.3 1.7 3.5 2.8 2.2 1.7 12.9 3.7 4.3 2.1 1.9 2.7 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol 1300000 Nucleoplasm Cytosol "HPA063616: " "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favourable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.9 19.8 7.6 8.1 22.3 12.0 6.5 8.3 19.9 19.4 23.5 19.0 7.4 1.7 13.2 15.5 9.5 11.8 10.2 20.5 3.7 9.0 5.5 9.1 15.5 27.3 0.6 5.7 11.1 18.4 14.9 13.1 13.5 4.9 1.9 22.6 7.8 2.8 2.8 3.5 14.5 3.6 23.0 4.1 26.9 11.5 4.3 7.7 9.7 6.5 24.4 29.1 15.4 14.0 22.0 14.9 31.2 13.7 10.2 13.4 0.4 26.1 7.7 7.3 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell line enhanced" "Detected in many" "A549: 30.0;SK-MEL-30: 46.2;WM-115: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm Nucleoplasm "HPA061967: " "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavourable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 30.0 17.8 0.8 2.3 0.0 1.5 2.3 12.8 7.0 3.1 0.3 5.7 0.0 6.3 1.0 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.2 13.1 5.7 0.1 1.3 14.0 12.6 0.0 2.1 3.1 18.4 0.3 0.6 2.3 16.1 5.9 0.1 9.9 3.2 15.2 46.2 3.2 0.3 16.0 5.2 0.0 0.0 1.6 3.6 0.4 0.0 15.6 2.6 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497838-110511544 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 85.9;Karpas-707: 33.3;U-266/70: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.4;non-classical monocyte: 8.8;plasmacytoid DC: 13.3" "Group enriched" "Detected in many" 19 "dendritic cells: 13.3;monocytes: 8.8;T-cells: 3.4" "Region enhanced" "Detected in many" "cerebellum: 68.0" "Region enriched" "Detected in many" 5 "cerebellum: 41.9" "unprognostic (1.25e-1)" "unprognostic (3.57e-1)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" "unprognostic (6.35e-2)" "prognostic unfavourable (8.30e-6)" "unprognostic (1.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.91e-2)" "unprognostic (1.20e-2)" "unprognostic (4.20e-3)" "unprognostic (3.79e-1)" "unprognostic (3.78e-3)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" 13.7 11.0 2.8 12.4 5.1 14.5 11.2 19.8 5.2 15.1 12.5 3.3 7.7 5.4 9.1 8.8 55.5 5.6 24.2 11.3 5.2 3.3 9.1 13.1 12.1 9.3 2.9 2.8 6.5 3.9 5.5 8.0 45.1 5.6 15.6 12.4 21.0 9.4 10.0 1.8 6.5 17.6 10.3 7.1 11.4 10.2 13.1 2.1 4.8 7.8 21.9 47.8 31.6 14.3 0.2 13.3 0.4 8.8 0.0 3.4 0.5 4.3 2.9 0.6 1.5 2.3 9.9 2.2 10.3 23.5 5.6 6.7 1.8 5.9 0.5 1.9 2.5 1.4 0.5 5.4 9.1 12.4 0.3 2.4 0.5 1.1 8.9 0.6 3.1 3.8 7.4 17.8 85.9 3.5 0.4 33.3 16.7 1.1 0.1 1.8 1.9 4.5 0.0 1.3 7.6 19.1 8.5 0.3 0.8 0.6 1.6 3.4 0.9 0.7 5.3 1.9 1.3 4.5 4.9 47.5 8.4 1.2 7.3 3.3 1.3 0.4 0.2 0.0 3.4 2.0 1.2 0.2 1.8 1.0 0.9 0.0 0.0 1.1 0.1 0.0 8.8 13.3 0.0 0.5 2.8 5.1 19.8 5.2 5.2 3.3 2.9 2.8 5.6 2.1 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell line enhanced" "Detected in many" "AN3-CA: 80.6;NB-4: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favourable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.0 80.6 20.8 17.7 0.0 8.7 11.1 1.7 1.3 7.0 1.2 0.0 2.0 3.7 9.3 0.1 21.6 2.5 0.1 0.1 3.6 0.2 11.2 14.7 15.5 39.5 3.4 7.6 15.3 14.3 40.1 0.0 3.8 5.5 0.5 0.5 57.8 14.6 19.7 39.3 3.0 1.5 24.8 23.3 0.4 17.1 0.2 0.1 45.9 1.2 8.6 10.7 5.9 0.1 1.1 4.1 0.6 3.1 0.0 24.5 10.9 37.4 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 40.7;hTERT-HME1: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavourable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.4 1.6 1.9 4.3 6.2 5.4 2.3 7.6 14.5 7.6 5.5 2.0 3.8 2.0 2.1 11.2 8.9 7.2 27.5 5.2 1.7 2.9 9.9 3.8 3.6 5.0 8.8 6.0 5.6 40.7 9.8 34.6 7.2 5.6 6.0 6.0 2.0 6.5 12.4 4.7 13.7 5.5 1.6 5.5 3.1 3.2 2.4 7.0 3.4 3.1 5.3 1.1 21.2 9.4 14.6 9.4 15.3 23.1 2.9 2.7 3.4 8.1 14.9 4.6 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell line enhanced" "Detected in some" "MCF7: 6.1;SH-SY5Y: 5.4;U-251 MG: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favourable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.1 0.4 1.2 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 1.8 0.0 6.1 0.0 0.4 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.4 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Cell line enriched" "Detected in some" 9 "Hep G2: 88.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 8.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.5 0.5 0.0 3.9 0.0 1.8 9.8 0.2 0.0 0.2 1.8 0.0 0.7 88.7 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.1 0.2 3.6 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.5 0.7 0.3 0.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.2 8.0 16.3 11.5 7.8 8.5 14.5 9.1 11.7 9.3 9.8 11.4 9.0 13.8 6.2 16.0 7.0 11.9 8.9 10.9 21.1 5.1 40.8 13.3 6.9 11.7 16.1 15.0 8.6 10.6 12.0 18.5 9.6 15.4 32.0 9.6 10.3 21.1 11.0 17.3 4.8 27.4 9.0 12.7 9.7 13.4 16.9 9.4 20.8 14.3 14.3 13.4 15.0 12.3 12.7 3.8 7.9 7.6 21.8 16.9 19.8 10.1 18.2 13.8 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Cell line enhanced" "Detected in many" "SCLC-21H: 12.1;SH-SY5Y: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported Nucleoplasm Nucleoplasm "HPA028522: , HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favourable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.3 5.9 4.7 4.5 0.7 2.7 1.7 2.5 2.2 0.8 3.3 1.3 10.6 3.2 2.9 1.2 1.9 2.2 4.9 7.2 0.6 5.3 0.8 4.0 0.3 1.8 6.0 1.2 0.8 2.8 0.6 1.3 1.9 0.4 4.2 1.9 0.7 2.0 1.9 0.9 0.1 0.6 5.4 2.1 12.1 13.7 4.2 4.2 0.2 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: " "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.5 7.7 11.5 8.3 5.8 7.9 9.2 13.8 9.0 6.8 3.9 10.1 7.5 25.4 17.1 20.0 15.9 9.2 5.4 7.3 10.9 12.0 4.1 5.1 3.8 2.2 9.2 8.9 6.5 7.8 18.2 14.6 3.8 5.0 13.3 8.6 7.8 7.9 4.5 10.0 12.4 21.1 11.4 11.2 7.9 17.1 15.2 18.0 5.8 7.8 8.0 5.3 7.8 5.6 10.8 10.2 7.4 10.9 6.3 1.0 14.1 10.4 6.3 11.1 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA075041 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA075041: " "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavourable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.4 0.8 4.8 8.6 7.7 0.1 8.1 17.9 7.4 9.6 0.2 1.2 3.7 1.2 9.5 0.7 4.2 6.5 7.9 0.0 2.8 5.4 4.4 0.8 13.7 3.7 3.5 5.4 4.2 12.8 35.2 5.7 10.3 0.7 11.4 0.9 8.1 2.1 6.8 6.4 20.2 2.6 0.0 2.3 0.1 4.9 3.6 7.3 0.3 9.9 0.9 0.9 4.3 15.5 5.9 7.5 6.7 2.9 1.0 4.4 9.2 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Cell line enhanced" "Detected in many" "HHSteC: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028065, HPA056073" Enhanced Enhanced Vesicles Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.9 4.2 5.9 7.2 4.6 2.3 4.7 5.3 5.8 0.6 3.1 5.8 0.3 6.6 4.0 2.9 4.3 4.2 4.4 6.6 4.0 0.8 3.3 16.6 3.5 3.2 4.9 9.3 3.7 12.3 7.5 1.6 6.6 4.8 4.0 3.2 8.6 5.2 1.8 0.7 2.8 2.5 6.5 1.9 0.0 1.5 0.4 2.3 3.3 1.8 3.1 0.5 6.3 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589682-108694846 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 57.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles Vesicles "HPA035066: AB_10601549, HPA049232: " "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favourable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 4.6 9.3 14.1 4.5 25.7 3.1 5.0 14.5 23.7 5.2 4.4 5.8 2.1 2.8 7.4 9.7 3.8 17.4 5.4 10.8 13.2 18.5 10.5 3.9 6.0 8.4 10.3 16.0 10.3 4.9 10.3 57.4 4.5 20.3 9.2 4.5 4.0 3.3 7.0 10.1 3.4 3.6 7.9 9.2 7.0 6.0 29.9 8.0 10.4 12.0 2.8 7.0 5.0 3.5 6.8 1.8 5.2 1.6 11.7 6.5 1.8 6.6 6.0 17.2 10.3 7.6 8.0 5.9 4.2 8.3 7.0 9.5 8.4 4.5 12.0 9.0 4.4 2.5 9.8 3.6 14.8 4.4 4.2 5.5 2.3 5.8 4.6 2.1 3.1 8.3 1.9 6.5 8.1 4.3 5.2 5.9 13.2 6.0 5.3 2.3 10.5 4.3 6.9 14.2 1.1 5.8 3.2 11.7 11.2 7.0 0.7 7.5 10.3 1.9 5.0 6.3 9.6 1.2 3.6 6.8 3.9 23.3 4.8 1.7 7.6 5.2 0.7 1.4 5.0 1.0 6.0 6.8 5.1 6.1 0.6 6.0 4.5 6.0 0.1 11.7 1.6 1.8 6.5 1.8 14.1 25.7 14.5 23.7 13.2 18.5 10.3 16.0 20.3 8.0 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38832005 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Enhanced Mitochondria 5700000 Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavourable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 33.0 52.0 17.6 21.7 20.9 14.7 29.6 11.4 19.8 14.8 34.1 19.5 19.8 25.8 16.8 15.4 30.2 18.9 30.6 130.6 18.6 15.5 40.0 105.8 16.9 19.6 22.2 17.2 16.0 36.5 11.5 11.3 32.8 17.5 20.9 27.1 20.8 27.4 15.2 130.9 18.7 24.4 27.0 13.3 28.1 24.8 26.2 20.6 15.9 24.5 43.5 21.5 21.3 19.3 68.7 60.7 49.9 61.1 61.4 72.6 83.3 12.8 56.5 8.8 14.5 34.2 17.8 12.8 6.3 11.1 5.6 5.7 36.2 25.5 20.1 24.9 15.0 6.1 14.6 15.1 4.4 69.6 8.1 24.3 17.2 29.2 34.8 25.8 24.7 23.6 39.2 7.3 12.7 13.2 11.5 33.6 12.3 24.1 17.9 14.9 5.8 13.7 20.4 26.4 40.0 35.3 29.3 11.0 14.1 33.2 16.5 17.5 22.2 58.0 11.1 9.9 8.5 9.7 5.9 25.5 29.5 19.2 15.0 33.3 18.9 49.1 61.1 49.9 51.9 46.8 48.9 68.7 50.9 51.2 60.7 62.2 45.7 51.4 8.1 61.4 38.3 41.4 72.6 83.3 17.6 20.9 11.4 19.8 18.6 15.5 22.2 17.2 17.5 20.6 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164583-32168281 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell line enhanced" "Detected in some" "AN3-CA: 3.2;Hep G2: 3.6;NB-4: 3.0;SK-MEL-30: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" Vesicles "Nuclear speckles" "HPA061173: " "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 4.5 6.3 7.3 2.6 7.6 4.5 5.0 6.3 9.4 7.1 6.7 8.4 8.7 4.7 6.4 5.5 4.3 4.8 8.4 4.8 8.2 4.4 4.3 1.8 4.3 2.0 25.7 3.9 14.4 2.9 1.3 2.9 9.2 14.1 6.0 2.7 14.7 3.9 5.3 3.8 12.9 5.8 3.0 11.9 3.5 3.9 2.3 7.0 0.2 3.1 8.3 2.0 5.2 6.8 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.3 1.3 3.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.1 1.2 0.0 2.0 1.3 0.4 0.0 0.0 1.9 0.0 0.9 3.6 1.1 0.0 0.7 0.0 0.3 0.3 0.0 0.7 0.3 0.0 0.0 1.7 0.9 3.0 0.0 0.0 1.1 0.1 0.0 0.2 0.6 0.5 1.2 0.0 0.1 3.7 1.4 2.2 0.0 0.8 1.7 0.0 0.1 0.0 0.1 0.1 0.1 1.1 1.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.3 7.6 6.3 9.4 8.2 4.4 25.7 3.9 14.1 7.0 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 37.1;liver: 91.2" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced "HPA036401: AB_10670165, HPA042021: " "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favourable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 4.1 1.2 1.2 1.7 1.4 0.1 1.5 0.5 1.2 1.7 6.4 0.8 0.4 5.2 1.0 2.0 2.9 0.8 3.0 3.2 1.2 0.9 37.1 91.2 1.9 1.0 1.7 0.7 0.8 2.5 2.7 0.9 1.3 2.1 1.7 2.6 8.3 2.7 0.4 0.7 1.1 9.9 1.0 1.4 1.7 2.4 0.9 0.9 1.4 2.1 1.7 1.2 1.8 1.0 1.5 6.0 0.2 2.2 2.7 2.7 1.1 8.2 3.5 1.0 0.0 5.2 4.5 1.1 4.0 1.2 2.6 2.9 15.1 5.2 0.0 15.7 3.9 4.0 0.0 3.3 5.5 11.0 3.7 5.8 0.9 15.2 3.4 0.7 0.1 6.3 4.3 2.6 2.4 3.8 3.8 4.3 5.0 4.3 0.1 3.4 2.1 4.4 0.0 7.0 0.3 10.8 4.7 3.1 4.5 7.8 4.5 7.2 16.6 6.8 1.8 1.7 2.6 1.3 0.3 1.2 3.7 0.3 0.5 2.6 2.8 0.2 2.2 0.0 1.6 2.1 1.0 1.5 1.1 2.4 6.0 0.2 1.6 2.7 0.1 2.7 2.0 2.4 1.4 1.1 1.2 1.4 0.5 1.2 1.2 0.9 1.7 0.7 2.1 0.9 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022244-6059230 "Enzymes, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: " "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavourable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 21.0 38.2 31.7 25.4 32.7 62.8 26.9 23.9 41.1 22.8 34.5 31.0 20.8 26.5 22.6 28.6 28.4 23.4 21.5 40.0 29.9 30.0 32.0 46.3 22.1 23.3 33.3 30.3 23.0 32.4 61.9 25.4 43.9 33.4 26.4 34.9 23.4 46.4 26.3 31.6 28.9 29.9 17.8 35.6 25.4 34.7 16.3 22.6 37.1 29.0 17.4 29.6 22.4 20.1 11.7 7.5 17.4 7.4 10.4 10.6 4.8 41.1 25.9 20.8 31.6 20.0 18.0 27.4 21.2 19.4 19.0 24.1 23.7 27.8 32.2 23.3 23.3 29.1 27.0 19.3 24.5 19.9 41.5 33.2 28.2 35.7 16.4 28.2 30.3 14.5 24.4 17.9 19.3 20.1 53.1 31.2 17.8 41.1 15.4 36.0 26.1 29.3 34.0 21.9 37.8 24.1 20.1 25.9 46.6 40.8 54.5 18.1 41.0 34.6 19.2 10.9 40.7 19.2 22.4 31.7 31.6 32.8 22.0 37.2 31.6 10.6 7.4 17.4 9.5 5.9 6.4 11.7 7.4 10.6 7.5 7.7 8.6 7.7 4.1 10.4 6.5 6.6 8.8 4.8 31.7 32.7 23.9 41.1 29.9 30.0 33.3 30.3 33.4 22.6 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157065 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: " "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 25.5 14.2 15.9 16.3 15.5 36.4 13.9 16.4 19.0 14.7 13.7 9.9 9.3 14.5 17.2 21.5 12.1 12.8 15.4 10.7 13.7 19.2 12.2 11.5 13.7 10.7 14.3 15.0 18.7 11.7 19.2 21.1 18.2 17.3 15.0 12.8 10.2 23.0 17.8 7.1 6.7 15.2 16.2 14.0 15.5 14.3 5.1 12.8 14.1 13.6 8.1 10.6 14.8 15.5 8.8 6.9 27.6 10.8 8.6 9.9 3.3 24.9 12.8 7.9 10.0 8.7 11.9 15.6 13.2 19.0 41.8 40.3 14.6 14.9 13.3 17.2 14.4 14.8 13.6 13.4 18.8 29.3 7.2 14.6 9.8 9.5 8.6 14.0 0.1 9.7 5.3 16.7 12.2 10.3 10.1 13.4 9.4 11.1 17.9 7.2 8.2 9.2 18.1 19.4 6.6 7.8 9.6 8.9 9.4 16.1 11.7 25.4 6.0 4.0 13.4 17.0 18.0 7.2 21.2 9.9 16.3 0.2 8.1 9.5 14.8 17.1 8.2 11.1 8.9 10.6 9.0 8.8 7.5 8.1 6.9 7.0 6.1 7.5 27.6 8.6 10.8 4.7 9.9 3.3 15.9 15.5 16.4 19.0 13.7 19.2 14.3 15.0 17.3 12.8 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.8 3.2 7.1 4.6 13.0 9.1 11.3 7.0 9.0 5.0 7.4 7.2 3.5 37.3 4.2 4.7 4.4 5.1 3.9 7.3 13.1 3.3 4.0 3.3 7.4 8.1 4.9 9.5 3.4 6.3 4.6 10.0 5.3 2.3 13.4 3.8 5.4 4.6 4.0 5.2 3.7 18.1 9.8 6.7 6.2 9.2 5.5 7.5 4.1 10.7 7.0 3.9 2.9 4.2 4.3 4.6 9.7 4.3 25.2 12.6 26.4 6.1 4.5 5.7 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934146-40035591 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 32.9" "Group enriched" "Detected in all" 4 "dendritic cells: 32.9;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol Cytosol "HPA011811: " "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.7 16.5 20.2 19.4 27.3 20.2 36.0 22.4 27.3 16.8 16.3 13.6 17.1 12.2 35.7 17.9 17.8 18.1 19.4 18.2 19.5 20.5 15.4 22.7 22.5 16.6 18.6 14.2 20.1 21.5 20.3 34.7 20.5 17.6 22.0 14.6 17.9 16.7 20.3 20.4 20.7 12.2 24.3 14.6 16.1 16.4 11.5 15.1 17.7 24.1 10.6 15.9 27.0 14.4 5.0 32.9 4.2 9.3 3.8 4.5 2.4 13.8 6.6 11.9 17.9 19.6 33.0 11.3 19.5 22.4 16.0 15.8 9.5 6.0 7.3 10.2 26.5 14.8 15.9 23.6 22.4 34.8 7.9 15.7 12.3 11.4 16.8 9.4 10.9 26.0 16.2 15.2 27.5 22.3 11.6 7.0 31.5 4.6 7.8 13.0 7.3 14.9 9.5 16.5 12.1 19.9 9.4 6.2 9.6 13.9 8.5 12.1 11.9 16.3 23.6 21.4 16.2 10.7 12.6 9.7 17.4 2.3 15.0 13.0 29.8 4.2 5.8 4.0 3.6 6.7 3.1 3.5 4.0 4.1 8.4 5.0 4.5 4.2 1.7 3.8 9.3 32.9 2.7 2.4 20.2 27.3 22.4 27.3 19.5 20.5 18.6 14.2 17.6 15.1 EIF4EBP3 4E-BP3 ENSG00000243056 "Eukaryotic translation initiation factor 4E binding protein 3" O60516 5 140547666-140549578 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 16.3;HSkMC: 15.2;Karpas-707: 18.0;SK-BR-3: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045537 Uncertain "HPA045537: AB_10965796" "unprognostic (7.29e-2)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-1)" "unprognostic (6.64e-2)" "unprognostic (4.84e-3)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-1)" "unprognostic (8.36e-2)" "unprognostic (4.87e-3)" "unprognostic (2.17e-1)" "prognostic favourable (3.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.82e-2)" "unprognostic (3.75e-1)" 19.3 23.9 6.8 8.0 11.1 7.4 25.5 3.1 7.9 11.0 34.9 9.7 16.9 8.8 11.2 14.0 17.2 26.5 13.6 27.9 6.9 6.0 18.5 32.2 16.0 18.4 13.7 10.4 15.6 34.7 1.2 6.2 4.9 17.5 14.5 12.4 18.0 34.0 27.5 78.6 17.5 16.3 16.7 16.7 11.1 19.4 21.8 8.0 7.2 18.3 24.6 10.7 16.9 9.9 14.6 42.2 8.0 17.7 7.9 16.3 8.4 0.2 1.1 1.0 1.4 12.0 12.6 2.1 0.9 0.2 0.5 1.0 2.1 0.8 0.5 5.5 2.2 0.8 0.4 1.1 0.7 1.8 3.5 0.1 2.0 3.8 16.3 6.1 3.1 15.2 1.5 1.0 0.7 1.8 0.3 18.0 0.7 0.0 4.7 11.2 1.4 3.8 4.9 0.7 0.2 1.8 2.2 5.8 0.8 1.7 14.5 4.7 1.9 7.3 1.4 5.0 1.0 3.2 0.7 1.6 1.3 0.5 3.4 12.2 1.3 2.4 16.1 0.5 4.3 17.7 5.3 14.2 7.9 3.9 13.5 14.6 16.3 12.9 8.0 7.9 12.7 42.2 6.1 8.4 6.8 11.1 3.1 7.9 6.9 6.0 13.7 10.4 17.5 8.0 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Supported Cytosol Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favourable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favourable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 14.8 15.3 18.7 11.5 23.4 6.7 19.4 20.0 27.4 33.4 14.8 21.8 35.2 10.8 27.3 14.4 12.8 18.6 17.5 16.0 17.7 19.0 19.1 22.8 13.6 15.4 17.6 13.6 18.9 12.6 14.3 17.4 12.7 23.3 15.9 18.0 13.9 11.1 36.1 28.8 13.4 12.3 16.0 15.8 16.1 12.1 15.0 15.5 16.0 19.9 13.8 20.3 14.7 12.0 16.2 12.2 11.6 18.2 15.8 20.8 11.0 14.3 15.1 11.5 11.0 17.0 14.9 8.2 7.4 13.4 17.4 15.6 12.5 6.1 27.1 11.7 14.2 9.8 12.6 17.6 20.6 4.9 5.2 18.2 10.0 20.6 15.2 9.8 13.6 15.7 27.2 12.0 18.5 16.3 20.4 16.8 17.8 8.8 20.8 16.7 12.9 5.3 15.8 11.2 10.4 17.4 11.8 6.9 12.0 8.4 7.2 14.1 13.7 11.3 11.4 12.0 15.7 12.4 10.7 7.1 11.4 20.8 11.9 11.0 12.2 11.6 10.1 8.2 19.4 14.4 20.8 12.5 16.6 18.3 11.8 16.2 15.0 17.0 2.8 15.8 18.2 12.2 15.6 11.0 18.7 23.4 20.0 27.4 17.7 19.0 17.6 13.6 23.3 15.5 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41091786-41180079 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favourable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 16.8 14.8 19.1 13.9 15.5 45.3 14.5 33.0 20.6 14.8 16.8 15.6 18.9 11.1 18.1 11.6 16.8 15.7 16.5 10.7 16.6 8.3 11.5 12.2 14.1 12.9 16.9 12.7 20.2 15.7 26.4 14.5 27.7 13.8 13.2 12.2 12.3 15.3 17.9 19.5 18.2 17.4 13.8 12.7 15.9 14.7 20.6 18.6 29.3 16.9 10.9 14.1 18.7 22.5 4.3 4.4 9.8 3.9 5.7 3.9 2.3 15.5 11.2 19.0 11.8 12.1 13.0 17.0 7.5 10.9 11.3 10.8 14.2 5.7 16.2 6.6 14.8 12.5 27.4 10.3 12.5 15.8 18.2 12.2 12.8 11.1 13.7 28.8 13.8 12.7 10.8 16.3 13.6 12.5 12.8 22.3 8.9 5.7 8.3 9.0 13.7 7.8 17.1 8.9 10.1 10.7 20.7 6.1 6.4 26.6 13.6 13.0 9.6 16.8 16.1 11.3 13.7 8.0 10.6 15.3 7.2 25.3 8.3 8.9 10.7 5.0 3.2 3.0 3.7 3.9 3.2 4.3 3.6 3.9 4.4 2.9 3.1 2.6 9.8 5.7 2.1 3.0 2.6 2.3 19.1 15.5 33.0 20.6 16.6 8.3 16.9 12.7 13.8 18.6 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm Nucleoplasm "HPA053643: , HPA055468: " "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favourable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.2 6.2 8.0 2.5 1.4 2.9 3.4 2.7 3.4 1.5 1.6 19.9 2.5 3.5 1.7 1.2 1.2 2.5 7.7 1.6 3.2 2.3 2.5 4.9 11.0 2.0 2.0 6.6 1.6 0.5 1.9 1.4 5.1 3.4 2.6 7.3 2.4 3.3 1.7 4.2 2.9 5.8 2.4 1.6 6.0 5.9 5.2 3.1 6.8 1.8 6.4 4.2 2.8 1.3 2.6 2.3 3.7 3.7 8.0 2.4 2.7 4.3 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 40.4;RPMI-8226: 18.1;U-266/70: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.7 0.9 2.3 2.2 1.8 4.4 1.9 4.2 1.3 1.1 1.2 1.2 2.8 1.3 1.4 1.4 1.2 1.8 3.2 0.8 1.0 2.6 0.9 1.8 13.5 1.2 0.9 2.0 5.1 3.6 11.5 2.4 1.8 40.4 1.1 1.5 1.8 0.5 0.3 1.6 1.9 1.9 18.1 1.1 2.9 3.2 1.9 1.8 3.0 4.4 1.6 2.6 2.3 1.1 2.6 2.5 1.1 38.1 10.0 2.2 2.1 1.3 1.8 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690326-23713500 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.5;stomach 1: 30.0" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.6" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 0.7" "Low region specificity" "Detected in all" HPA076875 Approved "Intracellular and membrane" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.3 0.1 8.1 0.2 0.0 0.1 0.1 0.2 11.4 17.3 0.2 0.1 7.0 1.1 0.1 0.9 0.1 64.5 0.1 0.1 0.0 0.2 0.1 1.0 0.5 0.1 0.1 0.1 0.5 0.0 0.8 0.1 0.1 2.6 12.6 0.2 14.0 0.1 0.1 0.1 11.8 0.9 0.1 0.1 30.0 0.1 0.1 0.2 0.1 2.2 7.6 6.3 3.9 0.9 0.6 3.6 0.4 1.5 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 12.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 3.6 0.4 0.5 0.3 0.3 0.2 0.3 0.3 0.3 0.1 0.9 0.3 0.4 2.1 1.5 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144085-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 110.1" "Cell line enhanced" "Detected in some" "AF22: 15.3;LHCN-M2: 5.7;RH-30: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 27.6;myeloid DC: 33.7" "Group enriched" "Detected in many" 5 "dendritic cells: 33.7;monocytes: 27.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001804, CAB002155" Enhanced "Secreted to blood" 1400000000 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 56.6 19.4 2.2 11.4 6.5 3.1 57.9 2.2 1.8 13.3 21.8 2.6 2.5 2.2 4.7 35.6 13.4 16.8 12.6 55.4 2.0 2.2 17.5 1.3 14.5 52.7 5.8 1.4 10.2 8.9 5.3 9.3 110.1 7.5 16.4 15.1 11.6 11.5 3.3 18.5 10.4 10.6 20.1 5.0 5.1 11.5 16.7 2.5 2.7 22.4 8.3 6.1 23.7 6.5 0.0 33.7 6.6 27.6 0.0 0.1 63.5 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 28.9 0.5 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 27.6 0.2 0.1 4.9 0.1 0.0 0.0 0.0 33.7 0.0 0.0 0.0 6.6 0.0 0.1 2.4 0.0 63.5 2.2 6.5 2.2 1.8 2.0 2.2 5.8 1.4 7.5 2.5 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197039191-197067267 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 95 "liver: 76.3" "Cell line enhanced" "Detected in some" "A549: 1.8;Hep G2: 2.2" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" 3400000000 "HPA003827: AB_1078794, HPA052139: " "unprognostic (1.46e-1)" "prognostic favourable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 76.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 43.6;pituitary gland: 42.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.5;HDLM-2: 9.4;RPMI-8226: 19.0;U-266/70: 15.9;U-266/84: 8.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "cerebellum: 18.0" "Cell type enhanced" "Detected in many" "T-reg: 13.6" "Lineage enriched" "Detected in many" 8 "T-cells: 13.6" "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favourable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favourable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favourable (2.66e-4)" "prognostic favourable (6.83e-5)" 1.0 1.4 1.0 6.8 1.5 0.0 6.7 18.0 1.0 3.5 3.9 0.2 3.8 2.6 1.4 4.7 5.5 5.8 2.4 0.6 1.2 2.3 9.7 20.1 3.5 5.7 1.1 0.5 1.9 43.6 12.7 42.8 1.4 1.8 9.3 3.6 3.8 9.1 5.3 0.3 10.0 6.4 0.6 1.1 2.3 4.1 0.6 0.3 8.5 15.3 2.7 11.0 3.0 3.6 1.8 1.0 0.3 0.0 0.7 13.6 1.5 2.4 0.2 0.0 0.1 0.1 0.1 2.3 0.0 0.0 0.0 0.0 1.7 10.5 0.1 3.0 0.0 0.4 0.8 1.8 0.0 9.4 5.1 0.3 2.4 0.7 0.0 1.1 0.0 0.0 3.2 0.0 0.0 0.0 1.2 4.7 0.0 1.0 0.5 0.0 1.8 0.0 0.0 1.8 19.0 6.2 3.3 1.8 0.1 0.1 3.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 0.1 15.9 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 4.7 1.8 7.7 3.2 0.0 0.6 7.5 0.9 0.3 0.7 0.0 1.0 13.6 1.5 1.0 1.5 18.0 1.0 1.2 2.3 1.1 0.5 1.8 0.3 FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128116 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 453.2;liver: 370.7" "Group enriched" "Detected in some" 7 "CACO-2: 25.6;Hep G2: 81.3" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 23 "neutrophil: 2.3" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol 32000000 "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" 0.4 0.1 0.4 33.9 0.4 0.0 0.4 0.4 0.5 0.4 153.5 0.4 0.4 137.9 0.4 0.4 0.4 0.5 0.4 0.4 0.4 0.2 57.6 370.7 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 97.7 0.4 0.5 0.4 0.4 0.1 453.2 6.7 0.4 0.4 0.2 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 25.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 81.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.1 0.0 0.0 1.4 7.5 0.0 0.1 0.8 5.6 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.4 0.4 FAM20B "GXK1, KIAA0475" ENSG00000116199 "FAM20B, glycosaminoglycan xylosylkinase" O75063 1 179025804-179076562 "Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007409 Approved Supported "Nucleoplasm,Golgi apparatus" 280000 "Golgi apparatus" Nucleoplasm "HPA007409: AB_10601649" "unprognostic (7.58e-2)" "unprognostic (1.12e-1)" "unprognostic (4.97e-2)" "unprognostic (6.23e-3)" "unprognostic (3.29e-1)" "unprognostic (3.07e-1)" "unprognostic (4.76e-2)" "unprognostic (7.70e-3)" "unprognostic (7.85e-2)" "unprognostic (3.93e-2)" "unprognostic (5.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.76e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" 18.2 21.3 17.7 12.8 20.9 8.8 26.0 16.1 26.4 15.8 20.8 10.8 13.3 8.7 18.5 14.7 17.5 14.7 17.3 32.9 17.1 17.2 16.2 14.8 14.6 9.1 16.1 19.9 19.0 10.1 22.5 16.9 15.2 15.2 15.6 13.4 14.5 9.9 18.8 19.0 11.4 10.6 25.9 13.6 10.5 14.4 6.8 9.4 7.3 16.5 7.7 9.4 17.6 28.7 4.9 3.6 2.3 2.3 4.4 4.1 1.5 17.7 16.2 12.6 13.3 22.5 23.8 14.0 14.8 17.0 10.4 9.4 8.1 17.7 9.1 19.5 26.0 13.0 12.8 10.9 15.3 11.6 8.6 29.2 15.3 10.3 11.3 19.3 18.5 13.8 11.9 14.2 11.1 12.8 32.5 13.5 16.6 9.9 8.4 7.0 16.6 3.5 10.3 13.3 12.2 8.7 20.1 16.9 41.4 15.6 17.7 15.1 15.3 14.2 13.5 16.7 14.7 22.9 19.9 11.0 20.1 8.0 16.5 9.4 16.5 2.3 2.0 0.6 3.8 1.7 4.1 4.2 2.4 3.5 2.2 4.9 3.5 3.2 1.9 4.4 2.3 3.6 2.7 1.5 17.7 20.9 16.1 26.4 17.1 17.2 16.1 19.9 15.2 9.4 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "Fanconi anemia complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 62.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavourable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favourable (7.80e-5)" 6.3 29.2 16.0 11.2 22.9 10.6 16.2 7.1 18.1 11.6 9.6 30.7 7.9 9.2 16.6 15.7 8.6 11.7 9.8 10.2 17.0 23.5 7.1 16.7 7.7 10.9 25.0 15.2 21.3 10.8 16.8 62.5 10.0 33.5 11.6 12.4 13.7 14.8 9.1 6.5 14.4 10.1 11.3 23.4 12.0 10.5 14.7 28.2 8.6 14.2 6.9 12.0 10.1 12.7 10.8 7.1 5.6 6.9 8.8 5.5 2.7 18.4 13.5 27.6 13.5 4.9 6.5 14.7 13.6 8.5 13.5 17.6 11.9 23.3 12.8 17.7 4.4 10.8 15.3 10.3 22.6 30.0 24.2 21.0 19.0 16.1 5.3 20.2 11.6 4.8 4.9 9.8 3.9 10.5 19.5 11.7 9.1 9.4 7.1 25.1 29.8 2.8 13.5 20.9 10.0 11.8 18.3 31.3 15.7 19.4 8.0 12.7 7.3 13.6 6.2 12.1 18.2 8.8 14.9 12.1 7.6 7.5 25.7 13.7 18.3 2.7 3.7 5.6 4.9 6.9 3.8 10.8 4.1 5.4 7.1 10.0 1.4 3.1 1.1 8.8 4.9 6.5 5.5 2.7 16.0 22.9 7.1 18.1 17.0 23.5 25.0 15.2 33.5 28.2 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Approved "Nuclear speckles,Mitochondria" Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavourable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favourable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 13.8 16.8 18.8 15.7 19.0 6.4 10.2 19.0 26.4 18.0 20.6 13.4 20.3 21.2 12.4 14.6 20.3 16.7 16.8 35.7 17.6 12.9 17.7 25.6 9.5 10.4 12.0 15.0 14.4 20.7 20.2 21.8 18.5 12.0 16.8 10.6 14.0 21.7 17.9 89.5 14.4 25.8 11.3 9.2 14.9 14.8 10.6 10.9 11.2 16.8 28.1 16.9 17.4 11.8 15.4 26.0 19.7 22.3 13.1 19.0 14.5 15.7 18.4 5.9 14.1 22.0 9.9 9.8 12.7 17.3 10.8 13.0 12.7 13.7 3.7 17.3 17.1 10.3 5.6 15.2 2.9 10.8 10.1 4.6 4.6 10.8 27.9 3.2 10.4 13.0 22.3 12.5 9.2 12.7 6.7 7.9 12.5 31.7 7.7 9.2 9.9 21.7 5.1 7.1 11.8 14.7 10.9 7.0 7.3 16.7 26.0 16.9 14.0 12.6 10.4 13.8 3.0 12.9 11.2 21.2 12.9 2.4 27.5 7.2 15.8 10.5 22.3 19.7 16.4 21.7 17.1 13.7 17.3 16.9 19.4 15.4 19.0 16.3 4.8 13.1 20.8 26.0 18.7 14.5 18.8 19.0 19.0 26.4 17.6 12.9 12.0 15.0 12.0 10.9 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.4" "Cell line enhanced" "Detected in many" "HDLM-2: 26.2;RH-30: 18.2" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054971 Approved "Nucleoplasm,Nuclear bodies" 110000 "Nucleoplasm, Nuclear bodies" "HPA054971: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.5 10.3 5.4 6.5 5.7 1.4 4.6 23.2 5.5 4.9 5.1 4.4 10.1 4.9 9.6 26.1 4.5 7.0 8.6 7.6 3.7 5.0 13.0 45.4 7.8 5.2 6.2 3.3 3.8 8.4 9.9 7.4 2.7 4.4 5.7 4.7 6.8 7.6 8.8 26.0 3.7 7.6 6.3 3.0 3.4 3.8 2.9 3.4 4.5 5.4 4.3 6.9 6.2 3.7 8.2 3.6 3.9 4.8 4.7 8.0 3.0 2.8 0.8 6.0 2.4 3.0 10.6 0.5 2.5 4.2 1.4 2.2 0.0 2.2 3.3 8.1 6.7 1.2 1.0 7.4 3.1 26.2 0.7 2.3 1.9 5.3 7.8 1.3 1.5 14.9 6.3 3.1 4.9 2.8 1.6 2.1 9.5 3.2 1.7 1.9 3.7 3.2 4.0 18.2 1.2 8.0 5.4 4.6 2.0 3.5 2.0 7.2 1.7 1.4 2.7 2.4 1.8 2.8 1.7 4.8 1.7 2.8 8.2 5.5 2.2 2.6 2.2 2.2 5.4 2.3 5.0 8.2 2.6 6.6 3.6 6.8 4.8 8.0 3.9 4.7 4.8 1.8 4.5 3.0 5.4 5.7 23.2 5.5 3.7 5.0 6.2 3.3 4.4 3.4 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad" P49789 3 59749310-61251459 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 11.9;U-266/70: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "naive CD4 T-cell: 38.3" "Lineage enriched" "Detected in all" 14 "T-cells: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favourable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 6.4 24.0 13.7 8.0 17.5 9.0 12.1 4.7 13.3 7.9 8.0 21.0 12.4 8.2 6.2 9.5 5.1 9.2 13.0 14.9 15.3 13.8 30.9 10.7 5.2 9.3 19.5 9.3 8.9 11.8 16.3 15.2 4.1 14.4 5.8 7.8 14.0 11.4 9.9 11.6 7.0 7.6 9.1 17.1 6.0 8.1 10.5 18.2 3.7 15.6 5.7 6.9 7.3 6.1 1.6 2.4 1.8 1.8 2.6 38.3 4.7 0.0 0.0 1.0 0.0 0.6 0.0 1.6 0.1 0.1 0.0 0.0 1.8 3.0 2.6 0.5 0.1 0.0 10.0 2.1 0.0 1.4 3.4 2.2 1.3 4.1 2.6 5.6 0.1 6.8 4.1 0.1 5.1 0.0 1.6 8.3 0.1 2.5 10.1 4.5 0.8 0.6 7.5 0.0 11.9 11.2 1.3 2.1 2.8 1.0 6.9 6.5 0.4 0.1 0.0 1.2 0.4 0.1 1.5 24.4 7.4 0.0 2.7 0.0 1.4 1.8 1.8 0.2 0.9 1.2 0.5 1.6 6.9 0.7 2.2 1.4 38.3 6.7 0.3 2.6 0.4 2.4 7.4 4.7 13.7 17.5 4.7 13.3 15.3 13.8 19.5 9.3 14.4 18.2 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 312.0;ovary: 80.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 79.9;RPTEC TERT1: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 7.8;T-cells: 4.6" "Group enriched" "Detected in many" 4 "amygdala: 34.7;basal ganglia: 20.4;cerebral cortex: 51.8;hippocampal formation: 36.9;olfactory region: 18.3" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavourable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavourable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 8.3 9.8 1.5 5.7 3.6 1.5 8.9 0.8 5.6 16.3 10.5 1.4 5.1 6.0 14.8 12.1 9.2 6.8 16.5 312.0 2.5 0.4 5.5 7.8 2.1 2.7 0.9 3.0 80.7 1.6 0.2 4.1 16.7 1.1 12.8 7.4 18.5 6.2 8.7 9.4 5.6 16.9 11.9 0.8 3.9 12.7 13.4 0.7 3.1 6.6 16.9 5.1 18.1 7.6 1.4 1.3 7.8 0.8 1.5 4.6 2.6 22.5 5.3 3.1 0.1 10.1 12.8 29.6 42.8 11.3 27.5 33.1 9.5 35.3 0.0 3.6 52.1 7.0 4.6 38.9 31.4 0.9 3.5 15.8 6.5 7.1 40.0 0.0 3.5 26.6 21.4 43.3 28.8 56.0 4.1 1.3 79.9 0.8 3.6 0.1 6.5 16.7 0.0 4.8 0.6 73.7 16.0 0.1 1.0 16.0 7.2 11.1 9.0 0.5 26.9 20.0 20.3 22.1 34.4 0.4 0.0 0.1 31.9 0.0 20.6 7.8 0.8 1.0 2.2 0.4 1.5 1.1 1.8 3.6 0.7 1.4 1.4 2.9 4.5 1.5 0.3 1.3 4.6 2.6 1.5 3.6 0.8 5.6 2.5 0.4 0.9 3.0 1.1 0.7 FKBP10 "FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FK506 binding protein 10" Q96AY3 17 41812680-41823217 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Vesicles "Intracellular and membrane" 5500 Vesicles "HPA051171: , HPA057021: " "unprognostic (8.30e-2)" "prognostic unfavourable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavourable (3.43e-5)" "prognostic unfavourable (4.99e-4)" 16.9 16.5 6.6 13.2 7.2 0.2 14.9 3.4 8.4 43.0 11.5 6.0 15.8 3.8 42.7 39.0 14.0 21.4 28.6 19.2 5.6 3.6 10.3 3.2 16.2 17.1 5.3 6.7 35.5 13.5 24.7 22.7 33.8 5.2 21.3 5.7 17.1 6.5 17.0 9.6 8.8 7.6 27.9 5.5 7.9 8.5 15.1 5.7 1.2 16.9 9.5 8.1 24.4 19.2 0.3 0.0 0.0 0.0 2.0 0.9 0.1 0.0 16.1 14.9 48.7 52.4 61.2 13.1 66.3 66.4 25.0 21.6 8.3 0.6 0.0 0.9 72.0 0.1 8.9 17.7 10.6 4.4 13.3 6.4 18.1 23.8 57.2 0.0 0.0 65.7 0.0 20.5 15.7 21.2 0.2 2.3 20.8 20.9 0.0 0.0 11.6 5.4 1.3 17.5 2.1 4.3 0.0 3.7 13.0 0.1 47.7 22.2 7.5 0.4 24.0 30.2 15.7 20.0 10.1 0.1 0.0 0.0 41.3 0.0 28.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 6.6 7.2 3.4 5.8 5.6 3.6 5.3 6.7 5.2 5.7 FKBP11 FKBP19 ENSG00000134285 "FK506 binding protein 11" Q9NYL4 12 48921518-48926474 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 175.6;salivary gland: 62.0" "Cell line enhanced" "Detected in many" "HHSteC: 46.2;Karpas-707: 42.0;RPMI-8226: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "MAIT T-cell: 37.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favourable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 5.6 4.6 1.1 8.2 1.4 3.7 3.7 0.9 2.2 7.5 6.9 0.9 21.6 9.2 4.4 12.9 4.4 4.8 8.1 3.4 1.3 2.4 4.8 38.4 5.8 16.6 1.0 1.3 3.7 175.6 0.2 12.3 3.3 1.6 4.8 6.3 1.9 62.0 20.9 1.4 1.7 7.6 2.9 1.0 18.7 10.0 1.9 0.9 2.2 4.7 4.9 14.5 8.2 4.3 11.1 8.3 1.1 0.3 5.1 37.6 7.3 2.1 2.8 0.5 0.7 12.6 19.1 1.0 16.6 23.9 18.4 21.8 10.7 12.0 32.4 0.5 27.2 8.9 5.8 7.3 9.6 6.8 1.2 1.2 3.0 0.1 46.2 0.6 0.9 21.3 14.2 14.1 26.3 10.4 0.4 42.0 6.7 6.0 4.8 1.1 1.4 5.3 13.3 0.8 42.0 2.3 0.4 6.9 2.0 5.5 8.3 3.7 0.5 1.0 8.3 3.6 0.7 0.3 0.3 24.6 20.3 16.4 2.2 0.7 5.9 0.9 0.2 0.6 22.5 0.3 37.6 11.1 15.6 17.7 0.3 4.8 9.4 14.4 1.1 5.1 0.1 8.3 6.4 7.3 1.1 1.4 0.9 2.2 1.3 2.4 1.0 1.3 1.6 0.9 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FK506 binding protein 14" Q9NWM8 7 30010587-30026684 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavourable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavourable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavourable (4.25e-4)" 8.8 7.4 8.7 9.2 7.3 5.1 8.8 17.6 7.7 14.9 7.8 4.1 6.9 4.2 12.1 14.2 8.0 8.1 8.5 9.8 7.1 5.2 5.4 9.2 7.6 8.1 9.2 5.2 13.0 9.8 8.6 27.8 10.7 7.1 9.8 6.9 8.4 7.6 10.9 3.3 6.4 5.3 18.8 8.1 6.7 7.2 4.2 7.1 2.6 5.6 5.9 7.7 13.4 8.7 1.6 3.3 2.7 1.2 1.0 1.6 0.6 3.4 2.6 7.3 17.0 19.1 24.5 3.4 17.5 16.4 6.1 12.0 2.2 2.2 1.2 8.3 15.3 7.5 4.1 6.4 12.3 0.6 5.8 2.7 4.9 6.4 9.7 1.9 4.8 15.3 6.7 10.6 12.6 13.5 4.4 2.5 11.0 1.4 1.0 2.4 3.8 4.7 0.0 4.9 4.0 6.1 3.0 1.9 6.4 6.2 14.0 4.3 3.2 2.6 10.9 6.6 7.7 11.2 6.9 3.9 4.0 2.1 9.3 1.9 20.3 1.9 1.2 1.2 1.3 0.8 1.0 1.1 1.6 1.1 2.2 1.6 1.5 1.3 2.7 1.0 0.5 3.3 1.4 0.6 8.7 7.3 17.6 7.7 7.1 5.2 9.2 5.2 7.1 7.1 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FK506 binding protein 1A" P62942 20 1368978-1393172 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 149.0;TIME: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 63.6;granulocytes: 88.4;monocytes: 94.3" "CAB004639, HPA051798" Uncertain 16000000 "CAB004639: AB_425434, HPA051798: " "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavourable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavourable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 106.0 42.4 67.3 55.0 114.8 44.4 63.5 15.8 55.8 33.2 39.7 22.1 33.8 32.7 45.5 45.9 42.7 33.8 32.0 36.4 51.7 30.6 41.9 41.7 59.2 84.1 26.0 36.5 41.7 57.7 20.6 21.7 65.0 22.5 34.4 49.4 21.4 30.8 40.6 38.9 31.5 37.1 56.0 23.3 68.0 33.0 21.1 28.4 47.4 62.2 39.7 48.3 48.1 37.0 13.3 63.6 88.4 94.3 14.5 18.6 84.3 69.9 19.4 15.5 22.4 52.4 65.7 20.4 44.5 30.2 35.7 33.1 19.3 27.2 28.6 14.3 41.4 32.2 19.9 81.3 46.9 8.2 21.7 29.4 9.1 36.8 32.2 34.1 16.3 38.2 26.0 32.9 34.0 149.0 26.9 14.7 41.9 8.7 33.3 47.0 33.2 38.0 28.6 27.0 34.7 46.0 17.7 25.8 19.5 22.0 44.3 73.6 17.4 29.1 172.6 132.5 22.2 28.2 32.8 7.4 15.9 30.0 22.8 34.6 29.3 23.9 79.4 88.4 11.5 94.3 10.2 12.8 13.9 13.2 63.6 13.3 14.8 14.2 77.9 14.5 90.3 31.6 18.6 84.3 67.3 114.8 15.8 55.8 51.7 30.6 26.0 36.5 22.5 28.4 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FK506 binding protein 1B" P68106 2 24049701-24063681 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1;intestine: 24.9" "Cell line enhanced" "Detected in many" "Hep G2: 22.8;NTERA-2: 22.2;SH-SY5Y: 16.1;TIME: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles Vesicles "HPA045572: , HPA051798: " "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 2.9 5.9 25.0 2.8 30.7 1.9 5.9 15.7 23.1 5.1 7.2 1.6 7.4 24.9 3.6 4.2 4.5 4.5 7.1 3.4 31.1 14.0 4.4 4.6 9.0 2.2 13.0 19.7 4.6 4.9 6.4 2.8 5.6 7.9 5.1 4.6 2.4 3.3 9.2 1.1 3.6 6.7 4.0 5.2 1.8 13.3 1.6 4.4 0.6 5.0 1.1 3.2 7.1 3.5 1.5 2.2 4.4 0.8 0.3 5.4 1.1 0.1 1.0 8.9 0.0 5.6 2.2 3.1 3.0 3.1 1.3 1.9 0.6 1.0 0.0 2.2 5.2 3.4 13.1 10.2 0.8 1.5 8.4 3.0 0.1 22.8 2.1 0.0 7.3 2.1 2.4 3.0 0.6 8.3 0.7 0.0 2.9 0.1 0.9 0.0 22.2 1.5 1.5 0.7 0.0 1.0 0.6 2.2 16.1 0.1 0.0 2.8 0.6 1.1 19.4 0.0 2.8 0.1 0.7 0.5 0.2 0.0 3.2 0.0 0.7 1.3 0.8 4.4 0.3 0.7 0.0 0.3 0.6 0.5 2.2 1.5 0.0 0.2 0.1 0.3 0.0 0.4 5.4 1.1 25.0 30.7 15.7 23.1 31.1 14.0 13.0 19.7 7.9 4.4 FKBP2 "FKBP-13, PPIase" ENSG00000173486 "FK506 binding protein 2" P26885 11 64241003-64244132 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 119.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" 400000 "Plasma membrane" "CAB025561: , HPA049405: " "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 18.2 35.8 28.9 20.2 35.5 12.1 20.2 18.8 27.1 31.3 28.0 20.3 87.8 39.0 24.4 102.7 20.8 25.5 30.3 28.0 29.7 35.7 40.3 89.6 18.8 17.0 39.3 24.8 22.1 107.2 34.0 57.2 59.2 29.0 26.1 21.9 19.4 59.3 116.6 11.8 18.5 30.2 19.7 28.5 20.9 31.1 19.8 20.6 12.4 63.2 18.6 18.8 21.3 23.9 21.3 119.6 29.0 25.4 20.0 30.7 15.5 24.0 31.7 17.2 34.7 37.2 21.3 24.4 29.2 29.6 22.1 20.6 31.2 54.2 17.8 46.5 35.8 31.5 13.6 24.2 10.5 22.1 11.8 19.8 42.2 31.9 48.9 16.4 27.8 24.7 36.1 29.2 32.4 17.5 14.8 53.4 26.2 39.8 17.9 25.9 20.0 28.6 16.0 17.0 64.9 39.9 24.1 24.0 20.9 20.0 56.7 32.1 21.8 14.2 16.6 26.6 23.7 42.2 15.6 32.5 10.1 14.5 35.6 17.3 30.0 29.0 24.5 3.4 24.1 25.4 30.7 21.3 19.2 23.3 23.2 20.5 13.0 18.1 9.1 20.0 20.8 119.6 7.1 15.5 28.9 35.5 18.8 27.1 29.7 35.7 39.3 24.8 29.0 20.6 FKBP3 "FKBP-25, PPIase" ENSG00000100442 "FK506 binding protein 3" Q00688 14 45115600-45135319 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol 980000 Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 11.7 13.2 28.1 10.2 40.7 9.8 15.5 25.1 32.1 12.0 14.6 11.4 8.3 13.2 9.9 20.4 14.6 8.8 9.1 31.3 26.0 24.4 16.5 20.5 8.0 14.6 23.2 23.8 9.9 10.9 15.0 17.1 14.0 22.9 17.9 15.2 6.6 10.7 12.2 113.3 11.3 13.9 12.8 19.6 9.9 10.6 13.5 22.4 12.7 12.4 24.2 16.5 12.7 9.3 19.5 27.5 13.5 17.4 15.4 19.4 13.0 36.9 41.2 60.0 31.5 26.7 29.2 23.7 22.7 26.1 36.0 39.7 36.0 31.8 19.7 24.0 25.6 30.8 44.5 29.3 51.3 28.5 26.6 16.2 32.0 46.5 26.4 28.0 17.6 27.5 30.6 20.9 19.5 46.8 23.4 14.9 42.6 45.2 44.8 37.5 30.4 39.1 43.2 44.2 23.9 57.5 42.8 36.6 14.3 36.4 22.7 34.8 53.1 21.0 30.1 27.5 47.6 14.4 17.4 25.1 44.6 30.7 16.6 19.3 25.6 11.6 14.6 13.5 13.0 17.2 15.7 19.5 17.5 17.6 21.8 13.6 16.8 18.8 2.3 15.4 17.4 27.5 19.4 13.0 28.1 40.7 25.1 32.1 26.0 24.4 23.2 23.8 22.9 22.4 FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FK506 binding protein 4" Q02790 12 2794953-2805423 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "vagina: 209.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Approved Enhanced Nucleoplasm,Cytosol 110000 Cytosol Nucleoplasm "CAB017441: AB_10618759, HPA006148: AB_1078875, HPA062857: " "unprognostic (1.46e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-2)" "prognostic unfavourable (7.65e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "prognostic unfavourable (6.12e-5)" "prognostic unfavourable (1.44e-4)" "unprognostic (3.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-1)" "unprognostic (3.14e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" 16.2 21.6 26.0 13.7 30.7 13.3 40.7 50.4 31.9 19.9 22.6 22.8 36.2 13.1 20.1 30.7 34.2 25.7 16.4 20.4 25.0 32.5 31.6 31.3 15.8 11.7 44.7 23.4 23.9 30.3 30.1 19.5 32.0 39.4 30.2 25.3 11.5 30.1 31.6 33.5 25.3 16.1 26.4 25.2 11.5 25.3 36.0 42.1 15.6 47.1 16.5 18.5 17.4 209.6 13.8 6.0 10.9 13.7 8.4 14.0 9.9 15.5 34.6 10.0 16.8 12.5 7.4 48.1 15.3 5.5 25.3 17.2 34.4 19.0 20.8 4.4 9.8 21.3 62.3 20.7 30.5 38.0 39.9 22.9 25.5 12.2 9.6 17.9 6.2 6.7 19.0 29.9 30.0 14.7 21.0 29.7 10.1 44.7 31.3 16.2 85.5 25.0 18.8 17.6 12.4 21.3 19.9 14.5 20.8 17.7 48.4 7.7 65.3 12.1 7.8 12.5 39.3 14.0 38.5 7.4 11.3 30.7 11.1 26.7 12.7 10.9 10.8 5.9 12.5 9.8 14.0 13.3 11.1 11.8 6.0 13.8 11.8 13.7 1.5 8.4 13.7 5.3 10.1 9.9 26.0 30.7 50.4 31.9 25.0 32.5 44.7 23.4 39.4 42.1 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FK506 binding protein 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 277.2" "Cell line enhanced" "Detected in many" "ASC diff: 101.4;ASC TERT1: 63.1;HHSteC: 79.4;HSkMC: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: " "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 78.8 20.7 9.5 14.2 15.6 4.9 36.7 2.4 10.9 16.5 29.0 5.1 29.8 2.2 18.6 16.9 29.2 19.4 17.9 26.3 10.6 4.2 44.9 30.7 19.7 55.9 15.7 3.6 27.2 43.7 8.6 33.8 6.0 13.1 18.3 8.2 11.8 30.4 25.1 277.2 20.2 36.7 18.6 18.2 32.3 25.0 14.3 12.4 20.1 24.2 9.8 16.8 22.5 18.4 4.0 30.6 24.9 31.2 11.8 42.3 39.9 4.9 2.1 9.5 14.2 101.4 63.1 0.1 2.7 0.1 1.7 4.1 3.7 0.8 24.5 2.5 0.5 0.0 5.6 11.9 4.2 9.6 5.3 10.5 1.8 5.2 79.4 6.6 1.0 95.9 48.2 3.1 29.1 10.3 11.2 10.0 18.6 3.1 27.3 12.4 2.4 1.6 12.2 2.4 11.9 7.9 3.0 3.6 2.2 2.2 2.5 0.5 14.0 7.8 22.7 2.5 2.2 0.3 3.7 4.5 5.2 31.1 0.8 12.9 0.9 13.7 31.2 19.4 20.0 27.0 23.8 3.0 28.2 20.8 30.6 4.0 42.3 30.2 24.9 11.8 12.0 9.2 10.3 39.9 9.5 15.6 2.4 10.9 10.6 4.2 15.7 3.6 13.1 12.4 FKBP6 "FKBP36, PPIase" ENSG00000077800 "FK506 binding protein 6" O75344 7 73328164-73358637 "Disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 33.0" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;Karpas-707: 1.4;SiHa: 2.1;U-266/84: 1.3" "Cancer enriched" "Detected in single" 9 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA061109 Enhanced "HPA061109: AB_2684430" "unprognostic (5.07e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-1)" "unprognostic (1.91e-1)" "unprognostic (1.05e-1)" "unprognostic (3.98e-2)" "unprognostic (8.72e-3)" "unprognostic (4.34e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-1)" "unprognostic (4.29e-2)" "unprognostic (1.48e-1)" "unprognostic (6.20e-2)" "unprognostic (9.15e-2)" "unprognostic (2.47e-1)" "unprognostic (6.86e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.6 0.8 0.3 0.0 0.0 0.0 0.6 0.0 0.3 0.3 0.3 2.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.8 0.2 0.7 1.3 0.0 0.4 0.3 0.3 0.5 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FKBP7 FKBP23 ENSG00000079150 "FK506 binding protein 7" Q9Y680 2 178463664-178478600 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 51.9;ASC TERT1: 32.2;HSkMC: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavourable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.6 4.6 1.5 4.3 4.1 0.7 11.1 3.5 2.3 20.5 6.9 1.0 10.0 1.8 21.4 21.9 8.4 12.4 12.8 12.1 1.5 1.5 5.5 7.4 6.8 5.2 4.0 1.8 34.6 4.3 1.5 11.1 8.2 2.9 19.5 4.2 7.1 4.9 9.7 4.4 4.0 3.9 19.9 3.9 3.0 5.3 8.3 2.2 2.2 8.7 8.0 2.3 15.5 9.9 2.8 5.8 0.2 1.6 1.2 2.8 0.8 0.0 0.6 6.0 8.9 51.9 32.2 0.5 10.7 17.8 1.9 6.3 0.1 0.6 1.7 2.4 19.5 0.1 2.2 0.9 3.4 1.3 1.2 1.7 2.4 1.7 8.0 1.0 1.2 21.6 0.4 7.9 1.1 6.3 0.7 1.1 8.2 0.1 1.9 1.9 1.2 0.9 2.5 10.5 2.3 2.7 0.2 3.2 10.4 2.3 0.0 1.8 0.1 2.0 5.9 3.7 2.2 4.2 1.0 2.1 2.1 0.8 6.6 2.7 7.9 0.0 1.1 0.1 2.3 1.6 2.8 2.8 2.0 1.6 5.8 1.7 2.2 2.4 0.2 1.2 0.0 4.5 2.2 0.8 1.5 4.1 3.5 2.3 1.5 1.5 4.0 1.8 2.9 2.2 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FK506 binding protein 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 32.5;neutrophil: 31.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: " "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favourable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 44.3 38.1 75.9 27.5 82.1 82.5 26.5 43.4 113.7 35.2 31.9 41.2 34.6 31.1 31.4 27.2 48.7 39.3 34.5 43.4 69.6 62.1 28.9 42.7 34.3 31.1 55.3 54.3 56.1 60.4 28.8 42.2 36.6 51.2 36.5 12.9 31.9 73.1 46.1 56.7 35.1 31.6 34.6 46.3 36.7 31.9 49.5 26.9 32.1 38.8 24.2 30.7 36.3 45.8 4.3 4.3 32.5 6.9 3.1 6.6 9.1 36.6 26.3 20.6 39.1 21.3 33.5 51.7 29.7 31.6 22.7 31.5 24.9 50.0 21.0 48.3 36.4 19.9 12.7 41.3 6.4 25.6 60.3 19.6 34.3 29.9 36.7 19.4 43.2 43.7 39.9 20.4 13.0 23.3 41.1 50.0 19.7 61.0 35.2 58.1 42.1 38.2 37.0 17.1 71.8 30.5 24.0 22.9 41.7 20.8 17.2 37.0 20.2 56.7 27.1 28.4 26.0 55.4 22.5 38.3 21.9 24.4 64.3 31.2 25.2 6.3 5.6 32.5 6.0 5.8 5.5 4.1 6.1 6.6 4.3 4.3 4.7 5.3 31.0 3.1 6.9 4.3 6.0 9.1 75.9 82.1 43.4 113.7 69.6 62.1 55.3 54.3 51.2 26.9 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FK506 binding protein 9" O95302 7 32957404-33006931 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 57.5;fHDF/TERT166: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: " "unprognostic (1.23e-2)" "prognostic unfavourable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavourable (5.80e-4)" "prognostic unfavourable (2.02e-4)" "prognostic unfavourable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavourable (7.02e-6)" 35.4 21.1 9.7 12.5 13.6 0.9 43.7 4.5 16.3 33.6 18.3 9.3 16.8 8.8 31.3 30.9 23.7 24.1 28.8 44.4 9.7 11.9 18.2 10.1 30.6 17.5 10.8 9.7 25.9 26.0 12.9 16.0 35.2 13.2 23.7 21.2 30.4 16.0 25.6 17.1 28.0 13.4 37.0 12.8 10.7 17.4 16.3 6.4 2.9 18.9 19.4 11.1 23.7 23.6 0.4 1.4 7.4 4.1 0.3 0.1 0.9 7.0 13.4 5.2 21.6 49.7 57.5 7.0 38.1 39.7 12.6 20.1 5.8 16.8 0.0 15.6 70.8 13.8 7.7 18.6 14.5 0.0 2.3 1.2 14.4 5.8 20.7 0.0 2.0 37.3 11.3 11.2 10.9 15.8 2.7 1.4 25.6 6.8 0.0 3.5 1.1 7.1 0.0 14.1 0.0 14.1 2.4 4.9 12.0 21.7 11.1 13.5 7.8 3.4 21.2 20.7 19.9 12.8 8.7 4.6 8.8 0.0 20.2 0.0 41.1 1.5 4.1 0.9 0.1 2.6 0.1 0.4 0.1 0.0 1.4 0.3 0.1 0.1 7.4 0.3 0.7 0.3 0.0 0.9 9.7 13.6 4.5 16.3 9.7 11.9 10.8 9.7 13.2 6.4 FMO1 ENSG00000010932 "Flavin containing monooxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 70.4" "Cell line enriched" "Detected in some" 7 "HSkMC: 21.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 36 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 36 "B-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023680 Uncertain "HPA023680: AB_1848966" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favourable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 3.4 3.6 0.1 0.1 0.3 0.0 5.6 0.1 0.4 5.6 0.8 0.3 0.8 0.0 2.5 3.0 5.0 3.3 1.8 0.9 0.1 0.0 70.4 1.0 0.8 0.1 0.1 0.1 5.9 2.4 0.1 1.1 0.8 0.2 1.1 0.0 4.0 4.2 1.5 0.1 4.0 14.4 1.5 0.1 0.1 0.5 1.6 0.1 1.8 1.7 5.3 10.3 1.4 1.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 FMO2 ENSG00000094963 "Flavin containing monooxygenase 2" Q99518 1 171185208-171211230 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.0;esophagus: 35.3;lung: 53.0" "Group enriched" "Detected in some" 57 "ASC diff: 24.0;ASC TERT1: 10.9;HSkMC: 28.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA028261 Approved "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" 40.0 11.8 1.2 1.7 4.4 0.0 22.5 1.5 0.6 7.6 5.0 0.6 2.9 0.3 1.9 3.5 35.3 6.7 2.0 17.4 1.8 1.2 9.4 1.8 53.0 5.7 3.9 1.2 6.1 2.1 1.8 7.0 0.0 2.4 6.0 0.7 8.3 14.0 1.3 7.6 1.7 1.5 2.5 1.9 0.4 2.4 3.3 1.3 0.4 5.8 6.8 5.5 5.0 10.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 28.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.2 4.4 1.5 0.6 1.8 1.2 3.9 1.2 2.4 1.3 FMO3 ENSG00000007933 "Flavin containing monooxygenase 3" P31513 1 171090877-171117819 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 170.2" "Group enriched" "Detected in some" 4 "ASC diff: 24.8;ASC TERT1: 18.8" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Region enriched" "Detected in single" 5 "pons and medulla: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favourable (3.46e-4)" "prognostic favourable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 9.5 2.0 0.0 0.8 0.2 0.0 1.3 0.1 0.1 0.2 0.8 0.1 0.1 0.3 0.6 1.2 1.7 2.3 0.3 0.8 0.0 0.1 6.4 170.2 3.7 1.5 0.2 0.0 0.9 0.7 0.3 2.7 0.0 1.4 0.2 0.1 3.6 0.9 0.1 1.9 0.8 0.4 0.2 0.1 0.1 0.6 0.5 0.1 0.0 0.8 1.2 2.6 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 18.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.0 1.4 0.1 FMO4 FMO2 ENSG00000076258 "Flavin containing monooxygenase 4" P31512 1 171314208-171342084 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 33.8;liver: 42.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.2;EFO-21: 7.9;HSkMC: 9.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA049100: , HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favourable (1.09e-4)" "prognostic favourable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favourable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 5.3 3.6 1.4 5.1 4.8 0.9 4.5 0.6 2.7 4.5 6.0 4.8 3.1 4.2 3.0 10.0 4.6 3.8 4.6 6.3 2.3 1.5 33.8 42.2 3.4 2.8 7.5 2.8 4.1 3.2 5.5 5.0 2.3 3.7 3.9 3.7 6.7 2.7 2.0 1.6 2.9 16.1 2.0 7.0 3.8 3.9 2.0 6.2 2.7 4.5 3.3 3.4 2.9 3.7 5.3 2.9 0.9 4.0 3.9 4.9 2.0 0.1 0.0 0.4 0.6 5.4 4.9 0.2 1.1 5.0 1.6 1.7 0.8 7.2 4.4 7.9 0.0 0.3 0.8 1.3 2.2 2.1 1.1 0.0 0.0 0.1 0.8 0.9 1.0 9.3 3.1 0.6 1.3 0.3 0.2 3.3 0.7 1.0 2.1 1.9 0.5 1.6 0.4 0.4 2.5 3.5 0.0 0.2 0.0 1.4 1.5 3.0 3.1 1.3 0.1 1.3 0.4 1.4 1.0 4.0 1.3 2.7 2.4 1.4 1.1 0.6 2.6 0.9 2.5 4.0 1.8 3.1 2.4 3.3 2.2 5.3 3.3 2.5 0.5 3.9 2.7 2.9 4.9 2.0 1.4 4.8 0.6 2.7 2.3 1.5 7.5 2.8 3.7 6.2 FMO5 ENSG00000131781 "Flavin containing monooxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 61.1;liver: 119.4;stomach 1: 38.6" "Cell line enhanced" "Detected in some" "Hep G2: 28.4;HMC-1: 6.4;THP-1: 7.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Group enriched" "Detected in many" 6 "basal ganglia: 5.5;cerebral cortex: 4.5;midbrain: 17.1;pons and medulla: 5.2;thalamus: 6.0" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favourable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 1.1 2.4 1.1 1.9 5.5 0.2 8.6 0.6 4.5 1.3 61.1 1.5 0.8 12.5 1.0 1.3 0.7 1.1 8.5 1.0 1.3 0.5 9.0 119.4 17.0 0.8 17.1 0.5 1.0 11.9 8.8 4.9 0.6 5.2 1.9 8.2 0.5 9.7 0.6 0.4 4.2 53.6 0.9 7.1 1.2 38.6 1.2 6.0 0.2 1.1 1.5 0.5 1.9 0.8 9.2 4.9 6.2 12.1 1.0 2.0 3.6 0.1 0.7 0.5 0.0 1.9 0.5 0.6 0.4 0.3 0.2 0.6 0.4 1.5 0.3 0.5 0.4 0.3 0.0 0.0 0.0 1.0 0.1 1.1 0.0 28.4 0.6 0.9 6.4 0.9 0.1 0.3 0.0 0.4 0.1 0.1 1.1 0.9 0.2 0.5 2.0 0.5 0.3 0.3 0.2 2.4 0.4 0.4 0.2 0.6 1.9 0.9 1.4 7.2 0.7 0.0 0.2 0.6 0.0 0.2 0.0 0.2 0.7 0.3 0.2 6.2 12.1 3.5 2.0 5.6 0.3 3.6 0.5 0.6 4.9 9.2 0.3 1.3 1.2 1.0 1.6 2.4 1.4 3.6 1.1 5.5 0.6 4.5 1.3 0.5 17.1 0.5 5.2 6.0 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735575-82751197 "Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 17.4;Hep G2: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria 1400000 Mitochondria "HPA059151: , HPA061358: " "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favourable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favourable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favourable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 12.0 29.4 25.7 3.1 32.7 8.9 5.0 24.8 48.1 10.0 11.0 44.8 6.4 19.4 7.8 7.0 4.7 11.9 6.6 38.1 24.7 22.8 41.7 34.7 7.4 2.6 28.9 25.3 14.0 14.9 17.9 11.9 5.2 34.2 10.4 8.8 11.4 24.6 11.9 14.8 5.0 12.4 6.6 30.8 4.4 10.7 4.6 25.3 0.0 8.2 3.5 2.7 5.6 4.5 0.2 0.0 0.0 0.0 0.9 0.4 0.2 0.6 8.0 2.2 11.8 3.6 3.0 1.5 1.4 1.1 2.8 1.4 10.4 1.7 0.1 2.0 1.3 0.3 17.4 1.3 1.0 0.5 1.2 6.1 6.7 32.3 9.9 0.1 5.2 2.5 4.6 1.1 0.0 5.4 10.9 0.3 0.5 0.9 0.1 0.1 1.4 6.6 1.0 0.1 0.0 5.8 2.2 3.6 11.7 2.7 0.6 7.5 7.8 2.2 1.2 0.2 0.8 2.9 2.1 0.6 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.2 25.7 32.7 24.8 48.1 24.7 22.8 28.9 25.3 34.2 25.3 FN3KRP "FLJ12171, FN3KL" ENSG00000141560 "Fructosamine 3 kinase related protein" Q9HA64 17 82716683-82730328 "Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056172, HPA065831" Approved Approved Nucleoplasm 14000 Nucleoplasm "HPA056172: , HPA065831: " "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (1.54e-2)" "unprognostic (2.09e-1)" "prognostic unfavourable (3.26e-4)" "unprognostic (2.31e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (1.26e-1)" "unprognostic (1.99e-1)" "unprognostic (8.84e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (3.71e-2)" 17.6 18.3 27.9 10.8 26.3 12.3 15.7 19.5 27.3 15.3 17.4 27.4 10.0 11.8 18.4 16.7 16.4 16.6 13.0 12.7 26.1 20.8 18.8 23.1 12.8 12.9 25.7 23.0 21.9 15.3 10.8 11.4 17.1 22.2 17.1 14.4 13.2 17.2 20.0 7.3 16.1 13.6 20.3 30.7 13.7 12.6 8.8 21.6 8.2 15.1 9.8 17.5 12.1 12.9 16.5 23.2 18.5 15.5 18.5 23.0 17.1 10.7 43.6 11.9 15.7 5.8 11.1 9.9 20.2 11.3 19.6 16.0 23.0 7.6 8.9 13.6 16.3 12.4 10.8 15.3 17.7 5.9 19.2 14.9 24.3 26.5 10.4 10.3 8.3 10.2 18.2 18.6 10.2 14.0 14.3 5.6 25.0 20.4 20.2 15.4 5.4 19.0 15.2 30.3 13.8 13.9 20.7 10.0 21.1 33.4 15.1 16.3 25.2 15.1 12.4 38.1 13.1 26.9 29.8 11.5 12.6 22.0 17.7 13.1 17.5 17.0 14.2 18.5 20.4 15.5 20.0 15.7 19.9 19.5 11.7 16.5 23.0 16.7 2.1 18.5 8.4 23.2 18.6 17.1 27.9 26.3 19.5 27.3 26.1 20.8 25.7 23.0 22.2 21.6 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favourable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favourable (7.41e-4)" 16.5 18.9 16.8 42.2 22.7 29.9 16.7 32.4 27.7 18.0 32.5 19.7 18.6 48.2 22.4 18.6 23.7 20.5 26.8 11.4 16.2 13.9 25.0 22.1 22.2 22.4 17.6 19.4 21.1 33.0 19.5 18.9 16.6 17.9 20.3 15.2 16.9 70.8 20.6 26.2 25.6 41.1 15.2 14.3 30.9 39.2 28.6 18.5 23.6 19.7 19.2 22.3 18.9 18.9 4.7 7.1 10.8 19.3 4.0 8.5 6.9 15.7 12.7 7.8 13.2 7.8 6.7 20.1 15.0 9.0 10.3 8.6 16.0 22.6 13.5 10.2 9.0 13.8 8.0 12.4 4.9 13.7 14.1 15.6 12.8 12.0 14.7 15.8 24.5 9.7 10.7 10.4 5.1 11.2 16.8 17.1 6.9 15.2 26.8 40.9 13.9 23.3 22.2 9.0 12.0 8.3 12.9 13.4 14.5 8.7 11.1 10.4 17.8 13.6 18.4 14.4 8.4 14.6 20.0 27.8 18.6 15.0 16.2 19.4 13.1 2.6 9.0 10.8 8.5 8.9 7.4 4.7 5.6 5.7 6.0 4.0 3.2 4.7 6.7 4.0 19.3 7.1 5.0 6.9 16.8 22.7 32.4 27.7 16.2 13.9 17.6 19.4 17.9 18.5 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501689-19522145 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074747 Approved Nucleoplasm,Nucleoli,Vesicles Nucleoli "Nucleoplasm, Vesicles" "HPA074747: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favourable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavourable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favourable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 20.3 18.5 30.6 11.7 34.3 17.5 23.9 13.5 32.2 18.1 31.0 24.5 23.0 22.7 15.0 22.6 19.0 13.4 17.5 40.7 31.1 17.5 21.1 21.3 22.1 13.1 29.2 20.6 9.9 28.3 35.3 13.9 15.5 20.8 21.4 32.5 12.5 20.4 24.9 42.4 18.5 20.8 27.2 25.3 10.1 22.8 14.8 23.8 9.6 17.9 21.7 12.7 22.8 12.4 4.6 7.4 23.9 12.4 3.7 7.4 4.6 14.6 17.6 9.7 11.5 46.8 17.4 13.9 15.1 26.0 11.8 14.7 10.0 26.2 11.0 19.5 22.0 12.7 13.5 17.8 14.4 11.9 20.8 9.2 17.3 21.6 28.4 12.1 8.6 18.3 28.9 12.6 14.8 15.8 5.1 11.4 12.8 26.4 10.5 11.2 11.3 13.7 15.2 17.8 15.9 29.2 22.5 11.3 10.3 14.7 17.6 13.9 18.0 14.5 16.6 10.0 9.0 13.2 9.2 10.7 10.1 7.6 15.4 18.0 8.9 23.9 11.8 6.4 5.7 10.5 7.3 4.6 6.8 6.6 7.4 3.7 3.6 5.7 19.8 3.7 12.4 4.6 7.4 4.6 30.6 34.3 13.5 32.2 31.1 17.5 29.2 20.6 20.8 23.8 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 22.5;intestine: 19.5;lymphoid tissue: 37.5;skin 1: 33.2" "Group enriched" "Detected in some" 7 "AF22: 9.2;NTERA-2: 19.7" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.4 0.4 6.8 0.6 5.7 0.4 1.0 1.1 4.0 0.3 13.0 8.2 8.3 8.0 0.4 22.5 0.4 0.5 0.5 0.8 7.6 4.0 0.6 0.3 0.4 0.4 4.3 5.6 0.4 0.4 0.3 2.6 0.4 8.4 0.3 3.0 0.2 1.1 0.6 0.6 33.2 19.5 0.4 1.5 37.5 1.6 0.3 4.9 0.0 0.4 0.6 0.3 1.0 0.3 0.4 0.1 1.4 0.2 0.1 0.2 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 19.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.4 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.0 6.8 5.7 1.1 4.0 7.6 4.0 4.3 5.6 8.4 4.9 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Cell line enhanced" "Detected in many" "HDLM-2: 35.8;Karpas-707: 52.7;RPMI-8226: 51.8;RPTEC TERT1: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Approved Vesicles "Intracellular and membrane" 4600000 Vesicles "HPA045635: , HPA047534: , HPA065444: " "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favourable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.4 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.3 0.2 4.3 0.0 2.8 1.4 0.2 0.1 35.8 2.9 0.1 8.6 14.1 1.5 0.3 12.0 0.4 0.2 0.6 0.4 0.1 2.0 52.7 0.2 0.4 0.3 14.6 1.4 0.2 0.2 2.2 51.8 48.2 0.6 0.2 0.3 0.1 9.4 0.2 9.4 11.1 2.2 3.5 2.3 10.9 0.3 15.8 6.0 0.2 7.4 15.1 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 5.6;salivary gland: 5.5;thyroid gland: 8.4" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;HeLa: 4.5;Karpas-707: 2.0;U-2197: 13.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045635, HPA047534, HPA065444" Supported Approved Vesicles Vesicles "HPA045635: , HPA047534: , HPA065444: " "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.2 0.0 1.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.1 2.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.3 1.0 8.4 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.4 0.5 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.5 0.5 13.6 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.3 0.1 0.5 0.0 0.2 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.5 0.3 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 38.7;ASC TERT1: 29.4;HHSteC: 55.2;HSkMC: 63.6;TIME: 24.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (6.36e-5)" "prognostic unfavourable (4.06e-4)" "prognostic unfavourable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 38.7 29.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.0 55.2 0.6 1.3 63.6 0.0 0.7 0.7 10.3 0.1 0.1 9.9 0.1 0.0 4.8 0.6 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.3 0.0 1.6 0.0 0.2 0.3 24.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Group enriched" "Detected in some" 8 "RT4: 29.8;SK-BR-3: 10.2;T-47d: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favourable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favourable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 29.8 0.1 0.1 0.0 10.2 0.0 31.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: " "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavourable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 0.6 5.0 1.2 5.3 3.8 1.7 3.4 3.9 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 GGTLC2 GGTL4 ENSG00000100121 "Gamma-glutamyltransferase light chain 2" Q14390 22 22644475-22647903 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 1.5;RPMI-8226: 4.5;THP-1: 2.8;U-2 OS: 2.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA045635, HPA047534" Uncertain "HPA045635: , HPA047534: " "unprognostic (2.58e-2)" "unprognostic (2.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.96e-1)" "unprognostic (4.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.06e-3)" "unprognostic (1.48e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.0 0.3 0.9 1.4 1.3 0.8 0.7 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.5 1.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 2.8 0.0 0.0 2.3 0.0 0.0 0.7 0.5 0.1 0.0 0.2 0.0 0.5 1.3 0.0 0.0 0.5 0.2 0.3 0.7 0.4 0.9 0.0 0.0 0.3 1.4 0.8 0.7 0.0 0.7 0.6 GGTLC3 ENSG00000274252 "Gamma-glutamyltransferase light chain family member 3" B5MD39 22 18516344-18518161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.2;salivary gland: 3.0" "Cell line enhanced" "Detected in some" "AF22: 2.3;HDLM-2: 1.4;RH-30: 1.4;SH-SY5Y: 1.3;U-2 OS: 1.6;U-2197: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045635, HPA047534" Uncertain "HPA045635: , HPA047534: " "unprognostic (1.37e-1)" "unprognostic (2.06e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.6 0.0 0.0 1.4 0.3 0.0 0.9 0.8 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 4.3 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996608-33097230 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1700000 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: , HPA069503: " "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favourable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 17.3 33.1 9.6 14.9 14.7 9.5 18.4 8.9 19.8 18.3 21.9 12.1 19.8 21.2 18.3 55.0 12.7 15.2 25.8 13.7 9.7 10.0 35.0 33.2 24.3 25.0 9.2 9.7 18.3 25.3 28.4 16.4 26.5 14.0 13.6 23.7 23.5 21.1 17.7 6.1 12.9 28.3 15.6 9.8 21.4 22.7 10.0 8.0 8.3 26.9 7.7 19.5 18.4 13.6 11.1 45.2 22.7 39.2 6.8 20.9 20.9 5.6 9.8 6.3 7.6 39.1 20.3 136.7 9.1 24.7 11.7 15.1 13.9 13.6 2.8 8.1 18.6 5.5 6.0 11.6 8.7 16.0 5.0 10.9 5.9 7.1 20.1 7.6 11.2 23.4 11.2 10.6 6.3 18.0 9.8 10.6 12.8 6.6 4.5 5.0 4.3 4.3 3.9 4.2 13.0 12.6 8.4 1.9 6.6 11.7 19.0 11.4 12.6 19.9 10.5 7.5 5.2 10.3 7.7 8.4 13.4 0.9 15.9 11.0 5.7 10.5 39.2 22.7 8.3 34.6 11.8 11.1 10.2 9.1 45.2 10.0 5.4 6.5 15.5 6.8 23.7 9.5 20.9 20.9 9.6 14.7 8.9 19.8 9.7 10.0 9.2 9.7 14.0 8.0 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236606-219245478 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.0" "Cell line enhanced" "Detected in many" "HHSteC: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043058 Enhanced "Secreted - unknown location" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 6.9 5.4 2.7 2.0 3.7 2.3 5.6 1.6 3.3 4.0 5.8 4.6 4.5 1.6 5.3 7.9 2.5 14.3 8.6 3.4 3.1 3.5 18.5 3.5 4.1 2.5 2.1 2.1 6.1 3.1 11.7 6.7 7.4 5.6 4.5 2.0 13.2 5.8 3.0 1.4 2.5 4.4 3.4 2.3 3.9 2.1 57.0 1.4 3.1 5.0 1.4 2.4 4.0 2.0 1.7 2.8 3.2 8.9 1.4 1.8 2.2 2.4 4.3 6.7 5.5 7.4 9.2 3.4 4.1 8.8 5.2 4.9 1.6 6.9 0.8 3.8 3.6 1.3 1.9 4.1 4.1 2.2 3.3 2.5 6.3 3.9 18.4 0.9 4.0 10.9 2.5 4.9 3.0 4.7 1.5 4.8 4.8 3.5 2.1 2.5 1.1 1.2 2.2 3.7 3.4 10.6 1.4 4.3 3.9 3.5 4.8 4.0 7.6 2.2 3.6 4.4 5.4 2.6 2.3 4.7 1.3 1.3 8.1 1.1 11.1 2.0 7.0 0.5 1.1 8.9 0.6 0.6 0.9 1.1 2.8 1.7 1.8 1.3 3.2 1.4 6.7 1.2 0.3 2.2 2.7 3.7 1.6 3.3 3.1 3.5 2.1 2.1 5.6 1.4 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase alpha and beta subunits" Q3T906 12 101745497-101830938 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease mutation, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" 47000 "Golgi apparatus" "HPA014558: , HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favourable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 15.2 6.5 21.9 11.9 23.0 15.2 12.2 13.9 25.6 14.0 21.3 10.3 5.9 10.3 9.0 6.5 11.7 7.1 11.0 15.9 17.9 13.7 11.0 7.3 19.6 20.3 14.4 13.0 6.6 11.4 29.9 9.0 10.8 10.9 15.6 22.5 11.3 37.6 10.2 10.8 18.1 14.5 11.7 13.1 15.4 15.2 7.4 10.8 24.5 10.5 8.6 12.6 14.7 14.8 3.9 5.8 5.9 3.4 14.2 16.4 2.7 8.3 8.1 3.0 5.1 25.6 12.2 9.4 11.9 24.6 11.8 15.5 6.2 5.9 17.5 8.6 16.3 10.9 14.0 15.3 18.5 8.2 7.3 7.5 7.5 8.8 4.8 6.8 15.2 9.4 8.5 11.2 6.6 20.7 11.6 5.2 11.0 12.7 20.4 9.6 10.4 5.9 4.8 15.5 23.5 19.0 21.7 6.6 5.4 19.8 14.1 28.0 14.5 4.5 20.3 11.2 6.1 9.3 6.6 14.3 14.6 10.0 12.7 10.1 6.9 5.9 3.1 3.4 16.4 2.9 5.4 2.4 3.6 8.9 5.8 3.9 4.6 7.1 1.2 14.2 3.4 5.8 2.6 2.7 21.9 23.0 13.9 25.6 17.9 13.7 14.4 13.0 10.9 10.8 GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.3;skin 1: 34.4" "Group enriched" "Detected in some" 4 "BEWO: 64.8;SK-BR-3: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 4.8;neutrophil: 1.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA005798: AB_1079026, HPA006420: AB_1079025" "unprognostic (2.26e-3)" "unprognostic (5.80e-2)" "unprognostic (8.35e-2)" "unprognostic (7.33e-3)" "unprognostic (2.70e-1)" "unprognostic (2.76e-2)" "unprognostic (4.43e-3)" "unprognostic (6.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-4)" "unprognostic (3.66e-1)" "unprognostic (3.40e-1)" "unprognostic (4.04e-2)" "unprognostic (2.14e-1)" 1.7 0.6 1.5 0.2 2.4 2.8 15.9 2.0 1.6 10.2 0.9 0.2 10.8 0.3 0.9 3.8 40.3 0.7 1.0 1.6 1.9 1.2 2.5 4.9 2.3 0.2 0.7 1.4 0.5 1.5 12.9 2.6 31.0 0.8 6.1 0.2 1.8 17.5 9.7 0.9 34.4 0.7 5.1 0.6 0.6 1.3 1.6 0.4 0.4 2.8 22.3 25.3 6.7 16.9 0.1 0.2 4.8 0.2 0.5 0.6 4.5 3.1 0.0 0.3 0.9 0.1 0.1 64.8 0.3 0.4 0.2 0.3 0.2 2.2 0.4 0.1 0.0 1.9 3.9 0.4 0.9 0.9 1.7 0.1 0.6 1.2 0.0 0.2 0.3 0.1 1.7 1.8 0.0 0.3 0.6 1.2 0.0 4.1 0.6 0.5 0.2 0.7 0.2 0.3 0.5 0.4 12.3 0.7 0.5 0.6 34.1 0.7 4.1 0.1 0.3 0.2 0.8 1.0 0.3 0.8 0.4 0.4 0.1 0.5 0.5 0.0 0.2 4.8 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.6 4.5 1.5 2.4 2.0 1.6 1.9 1.2 0.7 1.4 0.8 0.4 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667155-113737735 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 51.5" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266410-67286556 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.2" "Cell line enhanced" "Detected in all" "NB-4: 55.2;REH: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA048330" Approved Approved Vesicles Vesicles "CAB005021: AB_562360, CAB037248: AB_1078280, HPA048330: " "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 13.1 10.7 24.5 35.8 17.0 78.2 17.0 32.9 35.3 12.8 17.2 12.2 12.6 17.5 11.4 9.9 20.2 12.6 17.6 13.6 21.9 17.4 13.0 14.1 19.1 42.8 13.4 19.0 9.8 10.4 9.7 12.2 12.7 15.7 17.8 16.2 9.3 17.4 20.8 20.8 23.5 26.3 12.2 12.5 59.6 17.4 6.8 11.1 35.9 10.1 13.6 37.5 17.1 15.5 4.1 6.0 21.0 18.3 3.8 5.3 7.4 7.5 5.3 5.2 8.8 4.2 3.8 5.2 4.5 4.3 6.2 5.1 11.8 12.5 38.8 7.3 4.2 10.2 7.6 6.1 3.2 47.2 4.7 22.0 6.1 5.3 5.2 46.1 44.2 3.4 7.1 4.9 6.6 7.9 7.9 19.9 5.3 14.0 25.6 55.2 6.5 8.0 73.3 10.3 11.5 6.3 9.9 10.5 5.7 6.7 9.8 16.0 9.1 50.2 4.3 4.9 6.5 6.2 5.0 12.7 11.6 34.8 6.4 27.3 4.5 6.9 10.3 10.5 5.3 15.9 4.0 3.8 4.0 4.3 6.0 4.1 3.2 3.1 21.0 3.8 18.3 5.3 2.6 7.4 24.5 17.0 32.9 35.3 21.9 17.4 13.4 19.0 15.7 11.1 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564849-25729294 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.0" "Cell line enhanced" "Detected in many" "HDLM-2: 22.6;SH-SY5Y: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.8;eosinophil: 5.6;intermediate monocyte: 8.0;memory B-cell: 4.9;myeloid DC: 3.7;naive B-cell: 6.2;non-classical monocyte: 7.4;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favourable (1.29e-4)" 28.0 6.0 11.9 12.4 10.8 7.0 11.3 7.9 18.9 4.7 4.0 3.1 0.7 3.0 5.7 3.1 2.7 9.1 5.0 4.6 15.7 8.3 3.0 3.4 9.4 14.1 9.7 9.8 4.1 8.4 4.4 8.2 4.5 9.6 8.2 4.3 4.8 3.7 1.9 1.4 4.1 6.1 6.2 4.9 23.2 4.0 14.8 2.7 11.6 4.5 1.3 15.2 6.7 2.5 6.2 3.7 5.6 8.0 0.0 0.4 1.6 0.0 2.1 6.5 2.1 4.5 0.6 9.4 0.7 2.0 2.0 3.5 3.4 3.7 11.8 0.2 0.1 0.1 6.4 4.8 6.1 22.6 4.2 5.4 0.7 7.4 0.2 17.5 9.2 1.1 3.3 1.4 2.5 0.3 0.5 0.0 2.4 2.9 12.5 1.2 4.6 0.0 5.6 10.3 2.0 0.0 3.5 15.1 20.5 1.1 0.0 4.9 1.8 7.0 0.2 0.0 13.3 0.1 2.5 1.4 4.6 9.2 8.7 6.2 2.0 0.6 4.8 5.6 0.0 8.0 0.3 4.9 0.0 0.3 3.7 6.2 0.1 0.2 0.3 0.0 7.4 3.2 0.4 1.6 11.9 10.8 7.9 18.9 15.7 8.3 9.7 9.8 9.6 2.7 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 2.4" "Cell line enhanced" "Detected in some" "BEWO: 4.0;HeLa: 1.4;U-937: 1.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.2 0.5 0.3 0.5 0.4 1.5 0.2 0.9 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.3 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.2 0.2 0.6 0.3 0.7 0.2 0.2 0.3 0.0 0.4 0.2 1.6 1.5 0.4 0.0 0.2 0.4 0.1 1.0 0.1 0.3 0.1 0.3 0.7 0.2 2.4 0.4 0.5 0.6 0.1 0.0 0.1 0.1 0.6 0.4 0.0 4.0 0.1 0.0 0.0 0.1 0.2 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.4 0.5 0.2 1.4 0.2 0.0 0.4 0.3 0.1 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.2 0.7 0.4 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.4 0.2 0.0 0.0 0.5 0.2 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.1 1.7 0.2 0.2 0.4 0.3 0.4 0.2 0.6 0.6 0.5 0.3 0.1 0.7 0.5 0.5 2.4 0.5 0.3 0.2 0.2 0.1 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379569-6393981 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA022793: AB_1857946, HPA028707: , HPA070752: " "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favourable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favourable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 24.9 26.0 32.5 26.6 33.1 41.1 22.6 60.7 47.3 25.5 24.7 18.8 26.1 35.2 31.7 22.6 30.8 29.9 26.5 22.9 28.9 25.9 24.4 21.7 19.8 34.9 23.9 36.3 59.8 40.7 31.8 33.4 19.9 26.6 24.6 16.3 22.3 33.9 24.4 25.6 21.8 31.9 27.6 26.4 26.7 26.4 39.4 23.1 23.6 36.4 19.7 22.2 26.0 39.8 24.4 21.5 28.4 21.4 19.0 23.8 14.1 38.0 28.1 20.4 32.5 13.8 22.4 16.1 26.8 25.2 33.5 32.0 29.4 15.1 23.3 37.7 17.5 34.7 19.2 17.0 16.4 35.4 24.4 32.2 20.9 26.1 24.0 37.4 26.2 23.5 22.8 23.9 18.2 19.7 39.4 31.6 18.5 26.5 37.1 21.3 37.0 35.8 34.3 22.7 29.7 18.6 21.9 25.1 34.5 27.7 21.3 29.5 27.0 29.8 27.8 26.3 22.2 45.3 37.7 56.1 63.0 25.1 32.7 39.2 29.4 7.0 21.4 14.0 20.5 20.6 23.8 24.4 18.4 19.5 16.9 23.3 21.7 18.8 28.4 19.0 19.1 21.5 17.6 14.1 32.5 33.1 60.7 47.3 28.9 25.9 23.9 36.3 26.6 23.1 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694955 "Enzymes, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA069369: " "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favourable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 6.9 8.5 12.3 6.6 11.6 7.8 11.6 23.8 13.9 10.8 8.0 7.0 5.6 5.3 10.2 9.3 11.4 9.5 7.4 7.8 8.7 8.1 8.7 7.4 8.9 10.9 9.4 11.6 15.0 8.4 16.6 10.1 9.7 8.9 8.9 7.7 7.6 11.3 8.4 11.6 14.5 6.6 8.6 5.6 6.3 8.1 16.9 6.4 11.6 13.3 5.3 9.3 8.8 7.9 2.3 2.1 1.5 1.5 2.1 3.1 0.9 8.3 12.0 15.3 13.0 7.6 8.9 11.0 8.1 10.7 11.5 8.5 14.6 6.3 13.1 5.5 10.5 19.5 23.3 13.2 12.8 7.9 9.6 11.0 17.3 6.2 7.4 16.2 7.0 6.9 10.1 11.7 15.4 9.8 17.9 6.7 8.3 13.7 9.9 7.6 19.3 11.7 9.8 18.5 11.5 8.5 7.1 21.2 14.4 14.5 14.8 9.0 20.6 6.7 10.2 19.1 10.7 8.7 12.1 2.8 6.3 14.6 8.1 10.3 11.7 0.1 1.5 1.2 2.5 1.3 2.0 2.3 2.2 3.1 1.2 2.2 2.3 2.4 1.5 2.1 1.2 2.1 2.0 0.9 12.3 11.6 23.8 13.9 8.7 8.1 9.4 11.6 8.9 6.4 HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728093-104859919 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 41.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: " "unprognostic (6.32e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (1.12e-2)" "unprognostic (3.75e-2)" "unprognostic (3.75e-3)" "unprognostic (1.22e-3)" "unprognostic (4.63e-2)" "unprognostic (7.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (1.12e-2)" "unprognostic (2.06e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (1.75e-1)" 6.4 5.4 12.7 3.7 16.1 4.3 6.1 15.5 13.1 6.6 4.8 6.8 2.5 3.6 8.5 2.9 8.1 5.4 5.0 5.2 7.5 8.6 9.4 2.9 5.7 3.5 8.8 9.6 6.4 3.8 12.0 7.4 41.9 10.2 6.1 3.3 7.7 6.2 6.9 4.4 4.8 3.6 6.5 9.5 4.1 3.9 14.1 8.9 5.4 7.1 2.7 3.9 6.4 5.8 2.9 2.4 2.2 2.9 2.2 3.9 1.6 3.5 2.5 10.7 13.4 6.4 8.5 12.7 7.2 11.1 4.6 6.9 2.3 2.1 2.0 3.2 5.4 2.4 2.7 4.9 9.7 8.2 6.8 7.1 2.3 3.1 6.4 6.1 2.3 5.7 4.5 5.9 5.0 7.5 6.8 2.3 9.0 2.6 4.5 3.6 4.7 2.4 7.2 12.2 0.8 3.7 6.1 5.8 8.7 3.9 4.1 2.1 2.6 8.4 7.9 3.7 3.1 9.9 6.8 3.3 3.6 6.9 3.9 5.8 6.7 0.0 1.9 2.2 3.7 2.9 3.9 2.9 3.7 3.6 1.9 2.7 3.9 3.0 0.4 2.2 1.5 2.4 1.2 1.6 12.7 16.1 15.5 13.1 7.5 8.6 8.8 9.6 10.2 8.9 HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983682 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" 24.3 23.7 14.3 20.8 21.4 30.9 25.7 18.4 16.7 17.6 18.2 14.0 17.7 11.8 20.7 15.6 21.3 17.7 14.8 26.2 16.7 13.0 27.5 22.1 18.8 26.9 21.2 12.9 21.8 23.0 22.3 32.2 21.1 21.4 20.8 19.3 13.1 25.5 15.6 53.9 18.6 15.8 22.9 20.5 22.5 20.2 15.9 21.5 35.4 26.1 31.8 27.8 22.1 16.9 21.0 16.0 29.9 32.1 25.9 28.1 19.2 34.0 16.3 28.8 26.3 15.3 15.9 20.3 35.6 23.8 39.3 41.1 37.7 23.6 38.2 23.1 21.5 27.1 31.1 29.1 60.8 21.5 30.9 33.7 26.9 34.0 7.5 42.5 21.2 9.5 16.9 51.8 17.4 24.8 34.8 25.1 44.6 23.8 33.3 38.9 23.9 17.1 26.7 36.3 25.9 23.4 34.4 18.4 15.1 29.8 16.7 30.2 23.2 43.2 12.5 35.4 27.3 29.7 35.8 11.0 25.4 45.0 23.8 30.5 30.5 23.8 21.1 29.9 20.8 24.5 25.8 21.0 22.1 21.3 16.0 18.4 22.2 24.2 24.0 25.9 32.1 8.2 28.1 19.2 14.3 21.4 18.4 16.7 16.7 13.0 21.2 12.9 21.4 21.5 HDAC3 "HD3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636870 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: " "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favourable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favourable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavourable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 15.9 28.8 19.6 12.2 17.6 18.1 18.6 22.6 20.8 15.6 14.1 11.2 13.1 10.6 17.3 17.6 22.8 16.3 14.0 16.8 18.0 8.9 14.5 23.3 24.4 36.4 13.4 14.2 17.3 24.7 20.9 17.3 14.3 18.8 13.6 14.4 13.6 17.5 13.7 24.5 26.7 15.2 17.2 10.8 20.1 15.5 11.9 12.6 18.5 14.4 9.6 23.7 17.5 17.0 22.1 46.7 16.4 22.6 14.1 23.1 16.9 21.1 14.3 26.6 40.4 25.8 20.6 17.3 15.4 33.9 35.0 50.2 30.7 18.1 30.7 20.0 20.0 18.3 26.8 36.1 43.4 26.2 28.8 24.0 13.2 17.4 18.2 28.9 22.0 17.5 23.3 20.3 26.4 22.5 23.4 16.4 22.1 20.0 32.0 25.0 23.5 11.4 23.2 27.9 22.1 18.7 21.3 22.3 18.1 20.4 21.2 25.4 22.6 18.3 11.3 21.7 13.6 16.6 25.2 13.4 16.4 28.9 18.3 27.5 18.6 13.2 22.4 16.4 15.9 22.6 20.8 22.1 19.8 19.2 46.7 20.1 21.7 18.0 9.5 14.1 19.0 23.9 23.1 16.9 19.6 17.6 22.6 20.8 18.0 8.9 13.4 14.2 18.8 12.6 HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100112-31207804 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA002929: AB_1850574, HPA054461: " "unprognostic (6.71e-2)" "unprognostic (4.86e-2)" "unprognostic (5.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (1.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.29e-2)" "unprognostic (3.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.51e-1)" "prognostic favourable (1.20e-6)" "unprognostic (6.53e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (9.91e-3)" 22.0 22.3 14.2 21.0 16.8 22.0 18.5 22.3 18.9 19.4 17.9 15.2 20.2 11.5 17.6 15.7 30.4 16.1 15.2 26.2 13.5 14.3 18.0 35.2 15.0 14.1 14.5 14.5 18.2 15.1 34.8 20.5 27.0 18.8 16.8 15.5 16.8 18.9 16.4 88.5 24.3 16.3 15.6 13.7 16.4 18.8 18.9 14.4 16.7 24.8 23.0 18.6 18.6 22.3 10.6 9.3 12.6 8.6 8.9 8.1 3.3 28.4 17.8 15.7 9.8 49.6 26.0 15.0 17.4 17.6 15.6 13.5 13.3 15.4 22.3 18.5 31.8 19.3 20.8 15.7 23.7 13.6 8.5 22.8 14.7 53.1 23.1 23.7 16.8 22.8 21.8 17.5 27.5 28.6 16.4 10.4 24.2 23.3 9.2 10.1 11.9 16.2 17.0 18.1 9.7 24.3 29.5 11.6 13.6 25.5 17.7 15.4 18.6 15.3 28.6 18.1 14.2 13.0 14.7 11.4 16.1 25.2 8.6 12.0 15.2 12.6 8.6 11.3 7.1 7.1 8.1 7.2 8.0 6.3 9.3 10.6 6.7 6.6 4.4 8.9 5.3 7.8 8.0 3.3 14.2 16.8 22.3 18.9 13.5 14.3 14.5 14.5 18.8 14.4 HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "NK-cell: 6.7" "Lineage enriched" "Detected in many" 7 "NK-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037767 Approved Approved Nucleoplasm Nucleoplasm "HPA037767: AB_10671378" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.26e-2)" "unprognostic (3.34e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-2)" "unprognostic (9.37e-4)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.54e-3)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.67e-5)" "unprognostic (6.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.84e-2)" 8.7 8.8 16.5 6.9 17.9 2.4 10.8 20.3 19.5 14.3 10.1 5.1 9.1 4.6 17.2 16.6 8.3 12.1 11.4 8.1 11.9 8.7 7.3 4.7 8.7 4.7 5.8 11.3 16.8 7.4 14.4 18.6 10.2 6.5 24.8 7.6 7.5 7.7 24.3 7.7 6.8 6.0 18.4 6.8 5.3 7.5 9.7 6.4 2.9 9.8 5.1 3.6 13.7 10.5 0.6 0.4 0.1 0.8 6.7 1.0 0.5 4.0 2.1 21.2 8.7 4.7 5.1 3.8 3.3 4.5 6.8 6.3 0.2 3.9 0.0 2.9 3.4 0.3 5.7 2.4 8.4 4.4 7.1 2.3 14.9 1.3 2.3 0.4 1.5 5.2 2.2 4.9 4.2 5.1 3.1 10.6 10.5 1.9 2.5 1.3 8.8 2.1 6.3 14.0 2.4 4.7 1.1 5.0 5.3 6.5 1.5 6.6 9.6 1.4 5.3 6.9 4.7 0.4 6.3 0.7 1.4 5.9 6.0 0.0 3.9 0.0 0.1 0.0 1.0 0.8 0.6 0.2 0.5 0.7 0.4 0.6 0.5 0.6 0.1 6.7 0.2 0.0 0.1 0.5 16.5 17.9 20.3 19.5 11.9 8.7 5.8 11.3 6.5 6.4 HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved 34000 "HPA027467: AB_10600710" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.14e-5)" "unprognostic (1.74e-2)" "unprognostic (2.92e-2)" "unprognostic (7.42e-2)" "unprognostic (2.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.35e-1)" "prognostic favourable (1.85e-6)" "unprognostic (3.19e-1)" 18.4 16.9 9.6 16.7 11.1 9.2 25.9 12.4 14.8 11.2 38.0 14.8 11.7 34.1 12.4 12.4 16.7 9.1 14.6 8.7 9.9 8.4 16.4 22.9 10.5 11.3 10.9 7.9 14.1 24.1 22.9 8.0 11.8 10.8 10.4 19.5 9.7 27.0 15.4 24.2 20.1 59.3 12.0 9.9 14.0 13.9 11.7 9.7 11.9 13.3 14.8 12.5 13.8 12.0 8.7 9.9 10.4 15.1 5.0 10.9 7.5 11.2 10.2 6.5 10.6 23.1 14.5 13.0 10.8 16.4 11.9 13.5 14.5 3.5 5.3 9.2 17.6 10.5 15.5 11.2 10.7 9.8 12.0 8.5 14.9 12.7 20.2 6.6 14.3 15.6 19.2 20.3 7.9 26.5 18.9 6.0 15.1 9.6 8.3 5.4 9.0 15.6 9.9 11.8 7.6 17.5 13.3 15.8 6.6 14.5 25.2 12.8 8.2 6.2 19.8 13.8 11.0 17.1 12.2 7.7 9.0 2.9 22.1 7.2 6.7 9.4 10.4 10.4 10.9 15.1 9.1 8.7 8.9 9.3 9.9 5.1 7.5 8.9 4.0 5.0 8.2 7.5 9.0 7.5 9.6 11.1 12.4 14.8 9.9 8.4 10.9 7.9 10.8 9.7 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112599-43566001 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;kidney: 15.4" "Cell line enhanced" "Detected in some" "A549: 5.5;U-266/70: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Approved Supported Cytosol Cytosol "HPA007203: , HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.7 0.5 10.3 0.8 12.1 1.4 0.8 13.6 24.0 0.6 0.8 1.1 0.0 0.4 0.8 1.7 2.6 0.5 4.0 0.4 3.9 4.1 15.4 0.6 0.6 1.3 3.8 15.5 1.0 0.4 1.7 0.4 0.6 10.2 3.2 0.5 0.6 1.0 0.8 1.8 2.1 0.6 0.7 1.4 0.6 1.0 3.7 1.6 0.0 1.5 0.0 0.8 1.2 0.6 2.4 1.6 7.0 1.7 1.6 0.7 0.1 0.1 5.5 0.6 0.8 0.0 0.0 0.0 1.6 2.8 0.1 0.6 0.0 0.0 0.2 3.0 2.7 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.4 0.2 0.2 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.3 0.9 0.5 0.0 0.0 0.0 0.1 0.2 0.7 0.5 0.1 0.0 0.4 0.0 0.0 0.8 1.1 1.3 0.4 15.6 0.5 0.0 3.5 0.4 0.0 6.4 1.7 1.1 0.7 1.0 0.5 1.0 0.7 0.3 0.2 2.4 0.6 0.7 7.0 1.6 0.9 1.6 0.2 0.1 10.3 12.1 13.6 24.0 3.9 4.1 3.8 15.5 10.2 1.6 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593692 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 26.6;HUVEC TERT2: 15.0;SCLC-21H: 17.4;TIME: 19.7;U-138 MG: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.7;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 9 "granulocytes: 7.7;monocytes: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034609 Enhanced "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 8.8 3.3 6.7 2.6 12.6 0.6 4.2 15.7 17.2 4.6 1.2 11.6 0.0 1.1 3.0 1.0 5.5 6.3 4.8 14.0 6.7 4.3 3.4 5.6 16.4 3.5 8.2 9.3 1.3 2.1 14.7 5.9 15.5 9.5 1.5 1.3 1.2 2.2 1.3 2.7 2.7 1.7 3.1 5.8 11.6 2.1 5.8 8.8 0.0 7.9 1.6 4.2 2.4 2.5 0.6 0.7 7.7 5.2 0.0 0.1 0.1 0.0 0.7 1.2 0.0 0.7 2.3 0.9 1.5 3.9 1.2 1.4 0.1 0.0 0.7 0.3 7.2 1.7 0.5 0.1 2.5 26.6 0.9 0.0 1.1 0.1 0.1 0.2 0.2 0.5 0.7 8.9 3.1 15.0 0.1 0.0 3.6 0.9 0.0 0.3 1.4 0.6 0.0 0.3 0.0 0.0 0.0 17.4 1.4 1.1 0.2 0.0 0.0 0.1 19.7 12.0 0.8 2.6 0.3 0.1 0.0 0.7 3.0 0.0 0.1 0.2 0.5 1.3 0.0 1.9 0.0 0.5 0.1 0.0 0.7 0.6 0.1 0.0 7.7 0.0 5.2 0.0 0.1 0.1 6.7 12.6 15.7 17.2 6.7 4.3 8.2 9.3 9.5 8.8 HELZ2 "KIAA1769, PDIP1, PRIC285" ENSG00000130589 "Helicase with zinc finger 2" Q9BYK8 20 63558086-63574239 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 33.8;SK-MEL-30: 13.7" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA051267 Uncertain "HPA051267: " "unprognostic (1.86e-1)" "unprognostic (7.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.93e-3)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (5.06e-2)" "unprognostic (1.52e-1)" "unprognostic (1.73e-2)" "unprognostic (3.61e-2)" "unprognostic (2.19e-3)" "unprognostic (3.95e-2)" "prognostic unfavourable (4.92e-4)" "unprognostic (9.76e-2)" "unprognostic (1.16e-1)" 3.2 2.1 0.7 4.6 0.9 13.3 3.1 0.0 0.7 2.4 2.4 3.1 2.3 0.3 4.2 2.9 2.5 2.7 0.3 0.7 3.5 4.6 5.8 3.6 0.7 2.2 3.7 0.7 3.1 1.8 2.4 0.4 10.4 0.7 1.1 2.4 3.4 0.6 0.6 9.5 5.6 0.5 3.5 1.3 2.2 1.9 0.9 0.4 2.7 0.8 0.3 0.8 0.8 5.3 2.0 0.6 2.0 1.2 1.6 4.0 1.9 2.9 33.8 13.2 5.5 6.9 0.1 4.2 0.7 8.4 0.4 2.0 1.3 2.0 0.9 0.1 2.2 1.9 2.8 0.1 13.3 2.0 1.4 2.4 0.4 1.6 0.9 2.3 0.4 5.3 0.6 5.5 1.1 6.4 1.2 1.1 2.0 0.9 6.2 0.5 1.9 6.0 0.4 13.7 1.9 1.6 2.5 3.2 4.9 2.6 2.0 2.9 0.3 0.1 3.5 0.9 2.9 0.4 0.8 1.9 0.8 0.6 0.3 0.4 0.5 0.6 0.4 0.9 0.3 0.5 2.7 0.3 0.4 0.0 0.5 0.8 HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833942 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain "HPA049749: " "unprognostic (9.72e-2)" "unprognostic (7.51e-2)" "unprognostic (3.43e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-1)" "prognostic favourable (4.87e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.89e-3)" "prognostic favourable (3.66e-4)" "unprognostic (1.24e-1)" "prognostic favourable (1.36e-6)" "unprognostic (2.87e-1)" "unprognostic (3.36e-2)" "unprognostic (9.04e-3)" "unprognostic (3.94e-1)" 14.4 11.7 20.3 12.9 23.5 28.9 15.5 30.4 29.7 17.4 15.3 14.7 13.8 7.0 15.8 8.9 10.3 10.7 12.1 17.6 19.4 14.3 11.9 11.4 14.9 15.2 12.8 23.7 23.8 11.5 44.8 20.1 12.7 19.1 11.4 11.8 11.0 11.4 14.0 31.7 14.6 13.9 15.7 11.7 17.4 13.5 13.5 15.8 16.6 17.2 11.3 15.3 12.9 11.6 9.8 7.0 17.6 5.7 2.8 6.6 1.4 7.4 9.8 10.9 3.8 19.4 12.5 3.6 5.9 7.6 6.2 7.1 6.0 3.0 11.1 5.5 11.0 8.1 17.6 5.0 8.4 8.5 6.0 24.1 13.9 4.3 3.2 17.8 14.5 8.9 4.9 8.6 8.5 12.8 24.2 5.0 5.3 12.1 6.2 3.5 5.4 5.0 6.8 12.1 6.5 2.5 18.4 9.8 4.9 10.4 7.1 6.2 3.5 7.1 14.2 8.0 7.4 6.8 7.7 5.5 9.4 7.8 4.5 13.3 2.7 17.6 3.7 7.4 5.0 3.3 3.8 5.3 5.5 4.4 3.2 9.8 5.6 5.6 12.9 2.8 5.7 7.0 6.6 1.4 20.3 23.5 30.4 29.7 19.4 14.3 12.8 23.7 19.1 15.8 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 32.6" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB017188: , HPA048389: , HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favourable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 2.5 3.3 3.2 2.2 4.5 3.9 3.1 7.0 5.7 3.2 4.6 2.7 4.4 1.7 2.8 4.1 2.1 4.6 3.5 3.6 3.3 1.6 2.5 2.1 3.8 8.5 3.6 9.2 3.5 2.7 3.0 3.0 2.3 3.3 8.2 3.1 3.1 4.1 4.1 2.3 3.4 3.2 5.6 2.4 3.3 2.3 1.0 1.1 0.5 0.4 0.2 1.1 0.4 5.1 10.1 7.0 2.9 5.9 4.4 2.0 3.7 4.4 4.8 4.6 5.2 0.6 5.1 4.5 6.3 5.2 7.4 3.6 3.5 3.1 4.8 32.6 11.7 1.7 2.2 7.6 2.6 3.7 2.9 5.7 7.1 6.3 12.5 2.1 4.5 2.3 1.7 2.5 2.1 4.4 6.1 10.0 0.4 1.6 11.1 7.8 4.5 8.9 2.5 2.9 3.0 9.0 9.4 8.9 5.8 3.4 5.5 1.4 1.9 4.8 4.1 3.6 4.7 0.0 0.4 0.5 1.1 0.1 0.6 0.5 0.2 0.5 1.1 1.0 0.9 0.5 0.0 0.2 0.3 0.9 0.4 0.4 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592423-88708542 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039170 Approved Approved Cytosol Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favourable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 12.7 13.3 16.9 13.0 27.1 21.0 15.3 37.8 20.1 14.4 12.0 17.9 11.6 11.2 12.0 10.5 16.8 10.7 12.1 22.0 15.2 13.7 15.8 13.0 15.0 15.3 21.9 15.0 12.7 9.7 33.8 16.1 10.0 21.1 22.0 13.4 22.0 14.0 14.0 17.3 19.1 12.8 13.8 16.3 15.7 12.9 3.6 21.5 16.6 15.7 12.6 16.4 13.3 16.7 5.2 7.0 18.2 9.7 3.1 9.0 3.9 7.2 1.1 1.3 2.3 7.7 16.4 4.6 8.2 15.0 8.6 5.7 1.8 8.4 7.7 3.9 27.0 2.5 1.9 7.4 8.2 3.4 2.2 5.3 3.3 1.2 4.4 13.1 9.6 7.8 9.2 8.1 36.8 9.4 3.8 3.4 17.3 2.1 9.0 3.1 0.4 2.0 10.2 9.5 3.1 5.5 1.3 1.9 1.8 9.4 6.0 3.2 1.0 5.9 14.7 9.7 5.3 9.1 6.1 6.4 1.6 4.4 6.1 6.0 4.0 5.7 5.7 7.7 4.7 6.2 5.5 5.2 5.5 4.7 7.0 4.9 8.2 5.8 18.2 3.1 9.7 2.4 9.0 3.9 16.9 27.1 37.8 20.1 15.2 13.7 21.9 15.0 21.1 21.5 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075348 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 55.1;fHDF/TERT166: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: " "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavourable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 25.3 29.4 21.9 28.0 28.4 14.6 22.7 30.5 24.9 24.2 20.5 22.2 26.7 20.0 28.1 24.3 22.2 19.2 20.2 20.5 21.9 22.7 20.6 24.5 20.6 30.2 30.9 14.8 24.5 17.1 25.2 35.6 23.8 26.8 19.4 23.9 17.8 17.7 24.1 19.6 20.9 25.8 23.0 28.7 27.0 17.3 22.2 33.6 23.6 19.5 13.8 28.3 24.7 47.9 7.7 10.4 13.5 9.3 9.9 11.5 6.5 22.4 8.0 5.1 8.5 13.2 18.1 4.6 55.1 34.1 20.7 13.4 4.5 10.6 7.9 4.3 61.8 11.9 5.6 8.1 28.0 5.2 2.7 3.6 13.3 3.5 7.0 4.4 6.5 8.9 9.5 11.0 9.8 12.8 3.8 4.0 31.9 9.6 3.1 5.2 3.0 14.0 4.2 2.1 2.8 9.4 6.4 2.4 2.8 17.9 7.7 7.8 4.8 5.6 17.4 10.9 6.1 26.8 9.4 2.8 3.3 5.0 20.0 8.6 3.7 13.5 9.3 11.1 8.2 7.9 11.5 7.7 9.1 9.8 10.4 7.5 8.8 9.0 11.7 9.9 7.6 2.7 10.6 6.5 21.9 28.4 30.5 24.9 21.9 22.7 30.9 14.8 26.8 33.6 HIF1AN "DKFZp762F1811, FIH1, FLJ20615, FLJ22027" ENSG00000166135 "Hypoxia inducible factor 1 alpha subunit inhibitor" Q9NWT6 10 100529072-100559998 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048742, HPA065302, CAB069903" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB069903: AB_10000508, HPA048742: , HPA065302: " "unprognostic (4.07e-2)" "unprognostic (7.75e-2)" "unprognostic (2.35e-2)" "unprognostic (3.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-3)" "unprognostic (1.54e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-2)" "unprognostic (3.09e-2)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (3.24e-2)" 8.8 12.7 11.6 11.9 10.8 7.6 12.9 9.5 14.1 9.2 10.7 11.5 8.8 9.7 11.6 10.4 11.1 9.6 12.5 16.0 10.2 9.4 10.3 8.8 9.3 12.3 13.0 9.5 14.5 14.3 17.1 10.6 10.2 10.8 10.7 9.3 9.2 10.6 12.1 46.8 13.3 10.6 14.9 9.7 11.1 10.0 17.9 10.3 13.5 8.1 14.8 12.3 10.8 10.8 9.7 8.5 16.9 14.0 10.1 11.3 9.3 9.2 9.8 13.2 13.2 20.5 8.5 11.5 9.8 23.8 14.6 17.3 15.1 7.9 9.9 9.0 14.7 10.8 11.6 8.8 16.0 10.9 7.0 9.5 8.6 11.5 10.6 11.3 12.6 8.3 9.0 14.2 15.6 8.2 4.1 5.6 16.4 9.7 12.1 7.4 4.3 4.7 8.8 16.3 4.8 10.2 12.3 5.1 8.3 8.5 5.2 9.2 17.8 6.2 6.9 7.5 9.8 7.3 9.8 7.7 7.7 7.7 12.4 9.3 5.6 13.1 8.8 16.9 9.8 12.4 9.6 9.7 10.1 9.0 8.5 7.5 9.8 9.9 9.3 10.1 14.0 3.1 11.3 9.3 11.6 10.8 9.5 14.1 10.2 9.4 13.0 9.5 10.8 10.3 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929192-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.1" "Cell line enhanced" "Detected in all" "MCF7: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 15.1 16.8 21.2 14.7 23.0 90.1 13.6 38.1 20.4 20.4 14.4 20.7 14.5 10.2 15.5 14.2 18.7 27.3 17.5 27.9 22.9 17.2 14.8 13.8 19.3 14.7 15.0 16.4 18.7 16.8 20.7 23.8 13.8 21.3 14.4 15.2 20.7 13.0 14.9 19.7 18.5 13.4 15.1 18.3 15.9 14.8 33.5 21.3 47.2 23.3 13.1 15.5 17.3 26.7 2.3 6.2 9.8 4.2 4.3 6.0 2.3 8.1 6.6 9.2 7.0 10.8 5.7 6.2 5.6 6.8 8.0 7.7 7.6 3.1 10.9 7.7 8.9 5.5 11.8 6.6 11.6 7.9 6.0 15.9 8.3 8.0 9.0 12.7 19.7 6.1 9.6 10.2 10.5 11.8 10.8 11.8 11.5 61.5 16.6 7.2 9.4 5.9 10.1 27.0 3.8 7.2 7.0 4.1 5.4 10.2 11.0 7.2 6.4 18.3 11.5 7.9 10.7 12.8 8.5 7.4 5.8 9.5 8.8 10.3 17.9 3.4 4.2 8.2 5.5 3.7 5.2 1.7 4.9 4.9 3.1 2.3 5.0 6.0 9.8 4.3 2.6 6.2 3.6 2.3 21.2 23.0 38.1 20.4 22.9 17.2 15.0 16.4 21.3 21.3 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.1" "Cell line enhanced" "Detected in many" "HDLM-2: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favourable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.6 9.8 58.8 7.4 53.6 14.4 12.6 8.5 39.8 5.5 7.4 54.5 5.2 8.2 4.7 5.2 10.2 9.9 5.5 30.5 60.0 39.9 28.2 17.5 8.6 5.3 66.1 16.4 6.6 12.3 17.2 7.6 10.8 26.4 10.7 5.8 9.4 11.5 7.1 21.6 3.2 6.2 4.8 56.2 7.3 15.4 2.6 38.6 1.7 10.4 2.8 4.9 6.8 7.4 0.6 0.5 17.8 2.9 0.2 1.4 0.5 4.1 18.2 8.4 5.2 20.7 14.8 1.0 2.2 2.2 2.5 2.6 1.3 2.2 0.0 5.3 4.2 0.2 3.8 5.9 6.4 42.0 1.6 18.7 3.0 6.5 11.6 5.1 5.1 22.6 3.9 11.7 17.6 6.3 10.8 5.2 19.5 3.1 6.4 3.7 2.1 12.5 7.7 4.6 0.5 11.6 0.7 5.1 4.7 5.1 0.1 2.6 2.9 2.1 21.2 8.9 4.3 10.3 11.1 25.4 15.1 3.7 18.3 2.7 4.8 17.8 1.1 2.7 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.3 1.4 0.4 1.5 0.2 2.9 0.2 0.0 0.5 58.8 53.6 8.5 25.2 60.0 39.9 66.1 16.4 26.4 38.6 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 46.3 13.4 12.7 15.9 15.9 12.7 49.2 11.7 13.7 23.6 24.8 11.9 15.9 9.9 28.3 22.8 22.9 24.1 18.8 69.0 13.4 11.8 23.4 21.1 20.2 20.9 15.5 8.2 23.6 15.4 49.7 21.2 20.5 15.2 23.2 12.8 15.6 18.8 18.1 45.9 18.7 25.0 32.9 15.9 20.1 20.5 14.7 14.2 15.2 37.9 26.0 14.4 33.6 34.6 3.1 11.3 17.6 10.1 3.3 4.4 3.7 9.4 9.0 6.8 7.7 31.6 20.0 6.8 10.0 11.6 8.1 6.9 9.9 6.9 10.2 8.5 12.2 12.1 5.1 11.2 11.5 14.8 8.0 10.3 10.2 7.5 13.1 11.0 6.5 18.7 22.0 3.1 9.2 9.9 3.2 20.5 13.1 4.9 9.1 7.7 1.7 5.5 12.3 24.2 10.2 13.4 14.8 1.0 5.7 13.6 15.6 9.3 17.5 20.4 12.7 12.8 8.8 14.7 7.1 11.3 17.7 10.8 6.2 11.7 11.9 6.6 10.1 4.8 3.5 7.6 4.4 2.4 3.2 3.7 11.3 3.1 2.9 3.5 17.6 3.3 8.6 1.4 3.2 3.7 12.7 15.9 11.7 13.7 13.4 11.8 15.5 8.2 15.2 14.2 HLTF "HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3" ENSG00000071794 "Helicase like transcription factor" Q14527 3 149030127-149086554 "Enzymes, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015284, HPA049001" Uncertain Supported Nucleoplasm Nucleoplasm "HPA015284: AB_1857263, HPA049001: " "unprognostic (3.21e-2)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (1.95e-3)" "unprognostic (4.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavourable (7.27e-4)" "unprognostic (3.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.27e-1)" "unprognostic (4.78e-2)" "unprognostic (9.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (3.42e-1)" "unprognostic (2.83e-2)" "unprognostic (1.07e-2)" 10.2 22.1 12.6 8.4 17.6 9.0 12.4 29.3 23.8 11.1 11.0 12.4 6.2 4.8 12.4 9.6 7.1 10.8 8.6 16.5 15.8 16.6 15.6 16.3 7.1 9.8 15.7 19.0 17.6 12.0 16.5 25.1 7.3 29.9 14.7 7.0 11.3 9.3 11.1 9.7 5.1 6.6 12.7 19.0 7.5 8.7 37.7 14.0 17.1 19.0 4.8 9.6 10.0 7.8 8.4 9.2 8.8 2.3 5.4 10.4 3.5 24.6 12.0 17.1 13.3 11.4 14.9 1.7 16.7 10.0 12.4 14.5 9.7 17.2 15.9 20.4 7.7 0.7 22.9 6.6 20.7 8.7 11.2 38.2 9.4 3.9 7.1 10.0 15.8 9.4 3.6 9.2 5.4 7.1 13.3 10.4 16.9 12.4 20.5 15.4 12.9 15.1 23.7 19.3 2.5 10.2 8.0 16.9 10.0 25.3 11.7 22.9 35.2 9.8 5.0 14.5 8.8 20.5 18.1 15.3 8.6 20.8 14.3 13.7 5.6 8.8 1.3 4.0 5.6 2.1 10.4 8.4 4.9 7.2 3.9 5.4 7.2 7.4 0.2 5.4 2.3 9.2 4.4 3.5 12.6 17.6 29.3 23.8 15.8 16.6 15.7 19.0 29.9 14.0 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.4;BEWO: 12.9;RH-30: 14.2;SCLC-21H: 11.6;SiHa: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA027295: , HPA027372: " "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favourable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.4 0.1 0.0 0.0 12.9 1.0 0.0 0.2 0.0 4.1 0.1 0.0 0.4 4.8 0.0 6.2 0.0 0.0 0.0 3.1 0.0 2.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.9 7.9 0.1 0.1 14.2 0.0 1.1 0.0 11.6 7.7 10.2 0.8 0.4 4.2 1.1 0.0 0.0 7.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 4.9 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase" Q7Z6Z7 X 53532096-53686729 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol 3400 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 24.6 28.2 27.7 23.8 43.3 22.4 28.0 37.0 41.1 31.8 25.9 34.3 26.6 17.1 31.9 52.4 27.4 26.5 23.1 27.1 28.0 31.8 30.3 26.2 20.3 23.1 30.0 30.2 43.3 27.8 59.8 34.2 27.2 34.6 27.3 22.7 25.6 26.4 29.6 59.1 50.1 22.1 33.9 23.9 26.6 25.7 28.4 27.7 32.4 27.6 20.7 28.6 27.0 22.9 5.1 7.2 8.2 7.0 6.9 8.9 3.5 50.1 30.9 20.1 14.2 35.3 21.1 24.8 15.1 19.5 15.9 16.7 23.5 16.2 26.3 10.3 27.4 24.1 45.4 25.3 21.8 37.9 20.1 20.9 27.7 18.3 32.5 31.3 12.9 20.1 19.0 38.2 43.9 27.5 20.8 17.1 20.6 30.9 16.9 17.5 27.5 22.3 15.7 27.8 15.9 26.4 34.8 16.8 12.1 42.6 19.0 13.6 27.2 15.2 35.0 14.7 21.1 20.9 19.2 15.0 14.7 23.0 15.7 30.7 21.1 4.0 4.7 8.2 7.2 3.8 8.9 5.1 6.9 7.6 6.7 5.1 4.9 4.9 4.2 6.9 7.0 7.2 5.7 3.5 27.7 43.3 37.0 41.1 28.0 31.8 30.0 30.2 34.6 27.7 HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 17.5;U-266/84: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 7.1" "Lineage enriched" "Detected in single" 8 "T-cells: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040706 Approved Approved Vesicles,Aggresome Vesicles Aggresome "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" 6.3 7.5 6.4 4.8 8.0 1.7 7.7 2.3 6.1 8.2 14.3 2.5 6.8 11.1 6.4 11.0 7.0 6.5 7.5 8.5 4.3 3.5 19.4 10.5 3.6 4.3 3.5 3.6 9.7 15.5 4.0 8.8 1.5 4.3 8.0 6.2 10.1 7.9 10.1 8.9 3.9 21.2 9.4 3.4 1.6 6.8 7.8 2.2 5.7 7.3 3.7 4.1 7.1 5.1 0.4 0.6 0.8 0.2 0.5 7.1 1.2 3.1 5.1 0.5 9.0 2.0 4.4 1.9 1.0 2.1 3.0 3.5 1.7 3.7 2.5 1.1 2.0 3.6 8.2 2.7 2.8 1.1 17.5 1.1 2.2 4.2 5.1 0.3 1.4 4.0 5.1 1.1 2.3 2.1 3.0 6.5 1.7 3.8 2.9 0.5 0.5 6.5 1.7 9.9 2.0 5.6 3.5 0.9 1.2 2.2 6.7 7.9 7.6 0.2 0.9 1.9 1.4 3.6 3.3 10.2 17.8 0.1 2.2 0.1 2.7 0.8 0.2 0.5 0.3 0.1 0.4 0.4 2.4 0.4 0.1 0.4 7.1 1.3 0.8 0.5 0.1 0.6 1.0 1.2 6.4 8.0 2.3 6.1 4.3 3.5 3.5 3.6 4.3 2.2 ICK "KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Intestinal cell kinase" Q9UPZ9 6 53001279-53061802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Approved "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA000791: , HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 9.8 28.2 10.1 6.5 10.7 2.8 13.4 14.3 12.7 11.5 12.3 20.1 6.6 11.3 10.6 6.8 10.4 9.2 8.3 9.6 10.8 7.7 5.4 9.6 8.2 5.5 13.3 8.1 11.8 8.2 9.0 5.3 44.3 12.3 12.2 13.0 9.7 20.7 12.7 5.9 10.1 14.2 13.7 16.8 6.2 15.0 5.6 12.6 14.8 7.6 7.0 7.9 10.6 9.1 4.5 4.1 6.2 3.1 3.2 5.0 2.1 5.2 2.0 10.3 7.0 6.4 10.1 11.9 4.7 8.6 7.6 8.7 2.8 1.7 3.8 2.8 14.3 3.5 12.2 4.9 10.1 13.2 4.8 2.9 2.4 15.0 3.2 3.5 3.8 9.0 5.3 3.2 3.7 7.1 5.4 15.8 17.3 4.5 3.7 4.3 3.9 4.3 5.9 4.5 5.1 3.1 3.8 16.6 7.4 4.6 11.4 6.5 6.6 7.4 5.8 12.2 5.7 4.5 11.6 4.4 3.1 1.5 2.5 3.4 5.9 6.2 3.1 5.6 5.0 2.3 4.8 3.7 3.6 4.1 2.9 4.5 4.2 3.6 1.7 3.2 2.5 4.1 4.8 2.1 10.1 10.7 14.3 12.7 10.8 7.7 13.3 8.1 12.3 12.6 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332653 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Approved Cytosol Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favourable (1.46e-6)" 9.1 10.8 10.9 17.0 16.7 9.3 10.0 26.1 16.9 10.3 10.3 12.4 11.4 4.7 15.3 13.2 17.9 16.4 14.9 7.9 13.1 6.9 12.4 9.9 14.9 12.2 20.3 7.9 9.6 13.3 18.0 13.6 11.2 11.9 14.0 10.9 10.5 11.4 9.7 17.6 22.2 9.8 16.4 10.5 18.7 10.8 8.3 18.6 12.9 14.3 8.4 17.1 18.1 12.8 12.6 14.8 14.1 9.6 11.9 11.2 5.8 3.6 13.1 3.7 6.4 14.5 12.6 4.8 3.2 11.5 9.7 8.5 3.0 6.8 7.2 5.6 8.9 4.2 5.1 13.0 12.5 7.0 5.8 10.1 6.1 2.3 11.1 1.9 10.6 8.4 9.9 9.3 14.4 14.3 8.5 3.5 21.2 4.2 7.0 3.2 3.6 4.1 7.2 6.4 4.2 10.9 3.3 1.1 2.1 2.1 3.6 5.3 4.8 8.5 7.4 6.8 3.6 5.3 2.3 2.1 2.2 5.1 8.1 4.8 7.7 14.1 9.6 10.4 10.1 7.6 10.3 9.4 10.5 11.2 8.9 12.6 10.2 10.4 11.4 11.9 9.0 14.8 9.9 5.8 10.9 16.7 26.1 16.9 13.1 6.9 20.3 7.9 11.9 18.6 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 19.5" "Cell line enhanced" "Detected in many" "NB-4: 25.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.1 0.9 1.0 17.3 3.4 4.3 1.4 1.1 1.7 2.2 4.8 1.5 1.7 3.9 2.0 3.9 6.1 1.2 3.6 1.1 2.9 1.5 0.6 3.7 13.6 2.1 0.7 1.0 1.5 0.0 0.8 2.5 1.9 1.8 4.3 1.5 8.3 2.9 0.1 8.9 4.2 1.0 2.9 12.8 4.0 0.0 2.4 18.8 2.6 4.4 19.5 4.4 0.4 12.9 4.6 4.2 15.9 10.8 24.8 12.3 8.8 7.0 1.9 0.2 3.5 5.0 2.0 3.6 11.3 4.9 5.5 5.5 14.4 17.5 9.7 7.2 12.0 0.0 9.1 1.0 2.8 1.7 2.4 4.2 3.8 4.6 14.9 8.0 6.5 1.6 4.0 0.8 7.1 1.1 5.4 5.1 1.8 9.5 25.1 2.8 5.4 5.1 2.1 14.0 5.8 15.1 0.0 0.0 1.5 12.0 2.2 7.2 10.6 13.7 4.9 3.0 3.5 4.0 1.8 0.8 11.4 9.2 12.5 2.0 4.2 15.9 0.3 10.5 11.2 7.5 12.9 16.7 15.2 4.6 7.4 13.3 13.6 1.1 10.8 6.4 1.5 24.8 12.3 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Cell Junctions,Focal adhesion sites" 130000000 "Cell Junctions, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: " "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favourable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 20.9 17.6 11.0 22.3 11.9 7.5 37.0 9.4 14.6 40.2 75.1 14.7 41.9 13.5 75.4 25.2 35.7 33.2 41.1 35.1 11.1 9.2 21.6 15.1 21.9 18.9 11.5 14.0 24.2 22.3 20.4 10.9 22.2 11.5 39.9 24.6 19.3 19.4 89.9 18.5 12.4 22.2 103.5 10.6 20.2 33.2 14.2 11.0 8.2 17.5 14.1 13.6 60.8 25.9 19.5 45.9 76.5 49.4 45.3 25.8 63.7 23.8 18.4 29.1 10.0 44.9 31.9 13.2 35.1 69.4 41.6 50.8 19.2 28.1 9.0 9.3 57.4 19.2 16.2 29.7 41.8 15.7 14.8 12.9 17.6 14.9 30.1 10.3 14.8 30.6 14.0 28.1 21.5 39.6 11.8 10.7 54.2 17.9 9.1 17.7 18.3 21.6 9.6 15.2 9.5 30.5 19.1 5.0 11.4 16.6 23.0 19.3 16.0 11.8 45.8 52.2 23.6 21.6 17.0 7.8 4.8 12.6 38.7 15.6 24.3 48.3 49.4 76.5 25.8 47.9 25.1 19.5 23.3 24.4 45.9 17.1 14.7 18.5 31.7 45.3 44.4 18.5 25.7 63.7 11.0 11.9 9.4 14.6 11.1 9.2 11.5 14.0 11.5 11.0 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170401-238203729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm Nucleoplasm "HPA004752: AB_1851753, HPA056099: " "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavourable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 17.0 17.1 19.4 31.3 22.2 34.6 24.2 34.1 23.4 18.7 23.4 29.5 22.0 20.5 23.0 22.7 19.4 19.0 21.8 20.9 20.6 19.8 17.8 20.8 27.1 25.7 23.9 21.4 22.1 24.1 17.5 24.7 18.1 22.7 21.5 18.9 20.2 19.0 24.9 32.8 19.4 19.0 26.5 19.8 22.2 18.1 21.2 25.5 23.9 22.6 19.0 24.8 18.1 26.1 18.9 20.7 24.1 18.1 17.4 23.8 16.2 17.7 11.6 17.1 16.7 13.3 8.9 17.5 18.8 12.8 19.0 16.6 10.7 9.5 11.4 4.9 13.6 15.2 22.1 15.6 19.4 20.2 21.9 29.4 11.4 23.5 20.6 18.8 23.3 9.3 10.8 20.2 20.4 14.2 22.6 7.4 16.2 21.3 18.9 25.6 15.9 11.1 23.1 34.9 10.4 14.0 8.5 25.2 12.4 12.7 13.7 30.0 10.7 19.6 12.8 18.6 16.9 24.9 19.9 13.2 13.2 20.5 15.2 21.1 15.7 24.1 15.1 19.6 22.5 18.1 20.1 18.9 20.0 21.0 20.7 18.5 23.8 18.6 5.3 17.4 15.1 15.8 22.4 16.2 19.4 22.2 34.1 23.4 20.6 19.8 23.9 21.4 22.7 25.5 IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010500-154019980 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB004461: AB_2249106, HPA054476: " "unprognostic (4.46e-3)" "unprognostic (9.32e-2)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (7.09e-3)" "unprognostic (4.43e-3)" "prognostic unfavourable (3.03e-4)" "unprognostic (7.89e-3)" "unprognostic (3.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "prognostic unfavourable (2.06e-4)" "unprognostic (2.76e-3)" "unprognostic (2.36e-1)" "unprognostic (2.21e-3)" "unprognostic (3.04e-1)" 22.3 23.7 12.1 25.0 11.4 48.3 38.5 7.7 14.8 11.1 24.8 10.8 13.4 29.9 13.2 12.4 25.5 12.2 23.1 14.1 9.9 12.3 23.7 46.9 18.5 37.5 12.6 7.9 15.1 34.6 8.1 15.2 14.3 11.9 18.0 11.0 10.1 31.9 15.9 32.6 15.9 34.6 11.5 12.7 34.0 19.3 14.3 9.8 17.0 12.6 20.4 26.7 17.2 15.3 10.0 13.0 6.7 10.6 6.3 6.7 3.4 76.3 29.7 4.2 34.3 8.4 6.7 18.3 11.4 10.8 17.6 16.4 23.5 34.0 32.6 64.3 12.2 20.9 9.7 18.6 6.9 25.6 29.0 11.9 26.7 14.0 19.4 28.1 20.5 9.3 16.4 16.8 18.6 10.5 20.9 37.8 12.3 28.1 11.5 25.1 10.4 59.3 30.0 21.3 54.8 11.7 14.5 23.6 17.0 13.6 15.2 22.5 5.9 29.9 14.3 21.4 33.9 48.9 70.7 47.6 30.4 59.8 31.3 33.8 22.2 1.3 8.7 6.7 6.7 10.6 5.9 7.5 5.3 5.3 5.4 10.0 3.1 6.1 5.9 6.3 8.1 13.0 2.5 3.4 12.1 11.4 7.7 14.8 9.9 12.3 12.6 7.9 11.9 9.8 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164865-10243743 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.7" "Cell line enhanced" "Detected in many" "BEWO: 17.7;BJ hTERT+: 18.4;CAPAN-2: 18.7;RT4: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles Vesicles "CAB013483: , HPA050520: " "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favourable (6.60e-5)" 12.1 5.8 3.6 8.6 5.9 28.7 5.4 4.5 7.0 3.3 4.0 12.2 2.3 3.3 3.5 2.6 8.4 2.4 6.8 2.7 3.6 5.2 4.3 15.4 12.7 5.3 10.4 3.7 1.9 3.2 2.4 1.8 3.5 7.8 6.4 3.1 2.1 4.8 3.4 19.6 6.2 6.7 3.4 6.1 5.9 5.2 1.7 8.6 3.9 4.1 2.7 16.7 14.3 7.2 5.0 1.3 2.5 1.2 8.4 7.9 2.5 1.4 4.0 0.1 0.5 4.4 3.7 17.7 1.5 18.4 2.5 2.4 1.9 18.7 0.0 0.5 2.2 0.4 0.4 4.7 3.4 1.1 1.3 0.4 0.9 5.1 2.1 0.0 0.6 2.2 0.8 9.2 12.1 5.1 0.9 5.7 3.0 0.0 0.0 0.9 0.1 3.9 0.8 0.0 0.3 5.5 25.5 0.2 0.1 1.7 0.1 0.2 0.4 0.8 5.3 5.7 0.5 3.5 3.6 1.9 5.6 1.0 12.3 2.4 1.0 0.2 1.2 0.1 7.5 0.7 7.9 5.0 2.2 4.1 1.3 4.5 1.6 3.9 2.5 8.4 0.2 0.1 0.9 2.5 3.6 5.9 4.5 7.0 3.6 5.2 10.4 3.7 7.8 8.6 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66188879-66254622 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.0" "Cell line enhanced" "Detected in some" "ASC diff: 14.7;ASC TERT1: 12.2;HEL: 12.6;HL-60: 16.7;NB-4: 13.3;THP-1: 20.2;U-937: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 5.6;classical monocyte: 13.1;intermediate monocyte: 13.2;myeloid DC: 6.2;neutrophil: 7.2;non-classical monocyte: 20.6" "Group enriched" "Detected in many" 12 "dendritic cells: 6.2;granulocytes: 7.2;monocytes: 20.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavourable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 21.8 3.7 2.1 10.6 3.6 58.0 13.4 1.0 2.4 8.7 6.5 2.3 5.5 1.7 6.2 8.6 4.9 7.0 7.6 16.0 2.9 2.1 3.6 2.9 22.1 25.6 4.6 0.3 5.9 2.7 1.3 17.9 6.1 3.7 7.0 3.0 5.5 6.0 5.5 5.5 3.3 4.9 6.4 5.9 25.3 6.2 5.1 2.8 1.0 4.9 4.5 5.4 9.5 11.4 0.4 6.2 7.2 20.6 0.9 0.3 3.6 0.0 0.0 0.2 0.0 14.7 12.2 0.0 1.6 0.0 0.9 1.3 0.0 1.2 0.0 0.8 3.0 0.0 1.8 0.0 0.7 0.0 0.0 12.6 0.7 0.0 7.7 16.7 2.3 7.7 0.0 0.7 0.0 4.3 0.0 0.0 0.5 0.0 0.0 13.3 0.7 0.0 0.0 3.6 0.0 0.1 1.8 0.1 0.0 6.5 0.0 0.7 0.0 20.2 4.6 0.0 0.0 0.0 0.0 0.5 0.1 1.2 0.0 14.7 0.0 5.6 13.1 2.2 0.0 13.2 0.0 0.0 0.0 0.0 6.2 0.4 0.0 0.0 7.2 0.9 20.6 0.0 0.3 3.6 2.1 3.6 1.0 2.4 2.9 2.1 4.6 0.3 3.7 2.8 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favourable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favourable (4.42e-5)" 18.0 9.4 5.1 15.0 10.4 10.3 11.3 3.7 6.0 10.3 12.2 9.1 12.5 10.2 13.0 14.1 15.0 9.4 10.8 7.6 6.7 5.2 13.3 11.8 12.0 24.0 13.2 3.9 9.3 20.1 9.1 16.1 14.0 9.8 10.5 10.0 11.9 11.9 15.1 4.1 15.2 15.0 11.8 13.0 25.0 12.3 7.1 11.7 30.3 17.0 7.7 18.9 11.1 10.7 5.1 5.8 16.9 6.0 8.8 7.7 4.7 5.3 3.9 2.8 3.7 10.1 17.0 4.0 7.5 5.3 6.0 5.5 3.3 5.1 9.1 7.4 6.2 4.4 3.1 4.8 8.6 13.0 2.9 8.7 3.0 2.1 5.8 12.0 10.7 9.0 7.8 7.6 4.4 8.8 8.0 6.8 16.4 2.9 10.4 6.8 1.0 4.6 6.9 3.4 4.8 4.6 5.1 2.0 1.9 3.6 4.7 3.6 5.9 10.7 7.8 7.4 1.4 9.0 5.1 8.4 10.8 7.9 7.6 32.4 4.0 16.9 4.6 9.4 7.4 5.4 7.7 4.0 6.1 6.3 4.5 5.1 5.5 5.9 9.3 8.8 6.0 5.8 7.5 4.7 5.1 10.4 3.7 6.0 6.7 5.2 13.2 3.9 9.8 11.7 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511393 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: " "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 20.7 16.7 18.9 15.4 26.9 20.5 17.5 19.8 26.7 23.9 18.2 37.9 15.2 16.9 18.4 15.1 35.9 14.5 14.5 17.9 20.4 15.9 21.1 46.5 18.5 16.8 29.2 16.5 19.3 17.1 21.6 26.3 26.9 29.0 17.5 20.4 16.7 20.1 18.4 24.0 19.2 20.3 19.8 30.4 17.3 17.3 34.8 32.3 22.3 22.7 13.0 23.6 19.6 21.0 7.3 11.4 19.6 6.2 6.2 11.4 2.7 20.0 13.2 13.5 9.7 14.9 21.3 16.2 16.3 18.7 20.4 20.0 37.2 30.9 9.8 15.8 20.8 25.4 20.5 32.9 24.9 7.4 6.6 28.4 11.2 22.2 15.6 11.6 12.9 10.8 16.8 17.2 27.0 15.3 16.1 17.0 15.9 10.0 17.0 6.2 6.5 15.7 14.3 28.5 22.6 12.1 34.8 8.3 6.1 30.5 11.9 18.3 14.3 10.5 14.8 24.4 14.7 15.9 12.0 13.5 14.1 14.3 15.1 7.5 14.3 3.6 5.8 6.1 10.8 6.2 11.4 7.3 3.8 5.7 4.5 6.9 3.3 4.9 19.6 6.2 3.8 11.4 4.8 2.7 18.9 26.9 19.8 26.7 20.4 15.9 29.2 16.5 29.0 32.3 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell line enhanced" "Detected in many" "CACO-2: 32.1;HEL: 19.6;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.6 1.4 0.8 1.4 0.6 32.1 2.5 0.1 0.4 3.6 0.2 0.8 0.0 1.1 0.0 0.3 19.6 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.6 4.5 0.1 0.4 2.3 0.0 0.0 2.0 3.1 1.0 1.6 0.0 0.1 0.3 1.2 9.2 0.4 0.3 0.3 0.7 0.1 8.1 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035017, HPA035018" Approved Supported Nucleoplasm Nucleoplasm "HPA035017: , HPA035018: AB_10601763" "unprognostic (2.19e-1)" "unprognostic (6.94e-2)" "unprognostic (5.62e-2)" "unprognostic (8.72e-3)" "unprognostic (3.28e-1)" "unprognostic (4.35e-3)" "prognostic unfavourable (5.34e-4)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.01e-2)" "unprognostic (2.99e-2)" "unprognostic (2.04e-3)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-3)" "unprognostic (4.99e-3)" 15.3 15.2 8.2 15.4 10.8 15.9 16.9 10.6 13.3 16.6 14.0 13.6 17.8 9.9 21.5 15.3 12.7 17.2 12.1 9.2 7.5 4.8 13.2 9.8 13.7 9.9 10.9 7.3 20.1 17.5 17.0 13.7 12.4 9.6 16.5 9.3 20.2 16.6 19.8 15.7 14.2 15.7 18.0 6.1 15.0 13.4 36.0 8.4 14.8 18.1 10.5 11.0 20.1 14.8 3.6 1.4 4.2 2.6 5.7 5.9 2.8 9.2 5.6 18.9 14.3 7.9 4.3 8.5 7.4 11.8 14.8 16.1 10.5 6.2 13.6 10.8 11.6 6.0 13.3 7.0 12.8 9.0 10.6 18.7 5.8 11.8 10.6 12.8 7.4 10.9 4.9 9.9 8.4 8.2 12.9 9.7 9.2 5.2 23.0 10.1 9.2 9.6 18.3 12.8 7.4 8.7 9.4 20.2 12.4 8.8 9.7 8.6 8.4 4.8 12.2 10.3 9.0 7.6 6.6 8.1 5.0 11.5 5.5 14.4 9.5 4.2 2.6 0.8 5.8 2.6 4.3 3.1 3.5 5.9 1.2 3.6 2.6 4.5 0.2 5.7 2.2 1.4 2.5 2.8 8.2 10.8 10.6 13.3 7.5 4.8 10.9 7.3 9.6 8.4 KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113108-42121358 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain "HPA048958: " "unprognostic (1.71e-1)" "unprognostic (9.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (9.07e-2)" "unprognostic (1.91e-3)" "unprognostic (3.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "prognostic favourable (3.57e-4)" "unprognostic (2.78e-2)" "prognostic unfavourable (1.41e-8)" "unprognostic (3.97e-2)" "unprognostic (2.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.29e-3)" 16.9 15.9 30.2 13.6 28.6 8.6 14.0 24.0 42.0 11.2 11.9 10.9 13.1 14.9 13.9 8.9 11.4 14.2 11.8 7.6 27.8 11.5 10.0 11.8 7.2 11.2 27.6 18.0 23.5 16.5 14.8 11.9 10.7 26.0 12.9 9.6 6.0 17.3 14.5 20.1 19.9 13.4 9.7 13.9 15.6 13.0 7.8 29.7 5.3 11.7 6.4 10.4 11.2 21.7 2.0 1.6 0.1 0.4 0.6 2.7 0.8 11.0 21.4 3.2 11.8 4.5 3.7 14.0 7.2 3.9 16.1 8.0 14.4 9.1 21.8 18.3 5.5 16.6 13.0 11.5 5.7 12.1 26.9 5.4 13.2 13.0 4.7 14.4 14.5 4.3 9.8 9.0 5.7 6.4 13.6 4.2 4.2 11.9 34.4 10.6 6.8 0.0 8.2 6.3 14.4 4.3 11.2 15.3 6.7 7.7 17.0 5.9 12.6 6.9 4.9 8.2 8.3 11.8 12.8 11.2 10.7 12.1 5.9 12.5 4.5 0.0 0.4 0.0 0.8 0.0 1.7 2.0 1.9 2.4 1.6 1.6 2.7 0.7 0.1 0.6 0.1 0.4 0.3 0.8 30.2 28.6 24.0 42.0 27.8 11.5 27.6 18.0 26.0 29.7 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040023-20154404 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526" Supported Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB004526: AB_2128417, HPA002470: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 10.6 6.6 30.1 9.4 27.5 24.9 6.8 22.0 20.1 10.2 9.4 27.6 7.9 10.9 7.8 5.4 17.3 7.7 8.0 21.9 24.7 18.0 10.8 24.0 10.1 12.7 26.8 15.9 18.2 11.6 38.1 8.7 8.5 24.2 9.5 8.1 10.7 20.9 9.2 33.4 8.9 13.0 8.7 21.4 11.7 9.0 1.8 31.1 8.7 10.0 7.4 12.0 8.7 11.0 2.1 2.7 5.5 1.5 1.1 4.8 0.8 1.5 3.9 2.2 3.6 9.0 8.4 5.1 5.0 7.4 5.3 7.8 1.1 2.6 13.4 2.1 9.4 1.1 5.4 1.6 4.5 12.2 5.1 11.8 6.2 0.4 4.2 1.8 15.3 3.6 2.9 4.6 3.0 5.0 7.5 19.0 7.5 1.8 3.8 3.5 0.9 3.9 5.1 4.1 2.8 7.2 8.0 1.1 2.4 2.8 4.5 17.0 4.7 8.0 4.8 9.0 3.6 3.3 5.7 7.3 15.1 3.2 8.2 7.8 18.9 1.3 1.1 2.8 3.6 1.5 3.4 1.0 3.1 2.5 0.9 2.1 1.1 2.1 5.5 1.1 1.1 2.7 4.8 0.8 30.1 27.5 22.0 20.1 24.7 18.0 26.8 15.9 24.2 31.1 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016953 Approved Supported Nucleoplasm Nucleoplasm "HPA016953: AB_1851277" "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favourable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 18.5 19.5 21.2 16.0 27.4 34.3 21.6 29.4 37.1 22.1 24.1 28.2 22.3 16.5 30.1 24.8 21.2 32.9 24.5 21.1 18.3 19.2 22.6 16.1 20.8 18.3 19.0 25.7 29.5 23.2 38.8 22.0 32.7 24.6 21.2 19.4 29.3 23.6 27.5 24.6 27.6 19.2 25.2 20.1 22.0 21.9 30.7 22.8 26.9 26.5 19.1 22.1 24.4 22.0 25.0 24.0 40.4 23.6 24.8 28.6 23.3 19.1 23.4 21.3 16.2 16.9 17.9 22.4 13.9 22.7 23.3 20.3 17.0 22.9 17.6 19.9 24.3 16.2 26.5 23.3 14.1 22.9 17.0 25.8 19.3 20.1 24.3 28.1 31.0 19.0 26.1 15.3 31.4 14.6 26.6 27.6 22.0 34.8 23.8 32.9 18.6 15.1 19.6 14.1 32.2 21.3 29.1 19.9 20.9 13.2 25.0 26.5 24.5 18.2 18.7 18.9 16.7 14.9 14.9 21.2 21.8 25.9 16.3 13.8 15.4 23.4 23.6 40.4 25.7 22.3 22.1 21.1 22.5 25.5 24.0 25.0 28.6 23.3 26.1 24.8 23.3 14.5 21.5 23.3 21.2 27.4 29.4 37.1 18.3 19.2 19.0 25.7 24.6 22.8 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051990 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Approved "Nucleoli,Nuclear speckles,Cytosol" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: , HPA065052: " "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 20.8 10.9 15.3 19.8 20.3 36.8 22.6 29.9 18.7 19.7 14.6 19.4 14.4 10.7 20.6 12.1 16.9 16.5 14.3 13.0 15.5 11.5 12.3 13.6 26.9 28.2 23.2 10.3 27.2 13.1 26.8 22.3 20.9 15.7 14.1 12.0 12.8 15.1 17.0 21.0 25.5 18.0 25.0 22.9 20.4 14.0 14.1 21.7 30.4 17.9 14.3 20.1 16.9 24.2 4.7 1.8 10.9 1.6 3.1 3.9 1.4 12.9 10.6 17.5 11.1 9.8 11.2 5.9 8.7 11.3 10.8 8.4 6.7 6.2 19.2 8.7 8.5 8.3 13.6 8.2 12.7 9.9 7.9 27.6 6.6 5.0 7.4 14.5 12.7 9.3 9.4 10.0 12.4 10.3 23.1 12.2 9.8 5.7 29.5 4.6 6.7 4.2 23.6 19.6 6.1 5.3 14.9 10.9 9.4 10.1 6.8 7.0 15.6 6.4 12.0 13.3 9.4 11.8 9.3 10.0 16.1 20.8 7.1 6.6 11.5 3.5 1.6 2.8 3.5 1.2 3.9 2.4 2.6 3.3 1.0 4.7 3.6 2.9 10.9 3.1 1.2 1.8 3.5 1.4 15.3 20.3 29.9 18.7 15.5 11.5 23.2 10.3 15.7 21.7 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74825582-75032622 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favourable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 11.6 9.5 11.1 13.2 11.9 15.1 12.4 19.0 11.6 16.7 12.2 13.3 15.3 7.2 25.1 13.0 12.0 13.2 12.0 10.0 10.6 9.5 9.0 7.3 9.2 9.0 9.0 9.9 24.6 13.3 24.8 31.1 9.4 8.9 13.5 9.6 10.1 17.9 12.0 15.3 10.6 11.3 16.2 9.3 10.4 13.0 12.8 12.1 26.6 13.0 8.9 12.5 14.3 12.7 3.2 1.9 1.6 1.1 5.3 3.7 1.5 3.9 4.1 7.4 6.2 5.8 8.6 3.6 3.5 6.9 3.0 3.3 2.7 4.6 8.4 1.9 6.4 3.1 3.9 3.0 4.9 3.5 5.7 3.1 3.3 3.8 4.4 7.3 2.1 5.6 5.0 4.1 6.6 3.4 3.3 7.3 3.8 4.2 7.0 3.4 4.1 22.7 11.0 3.8 1.8 2.2 2.0 3.7 6.1 3.6 6.5 3.2 3.7 2.9 4.2 4.2 5.0 2.8 3.3 5.4 6.2 5.6 4.6 7.8 0.9 0.7 1.1 1.6 3.2 0.9 3.4 2.4 2.4 2.7 1.2 3.2 3.7 3.4 0.9 5.3 0.8 1.9 2.4 1.5 11.1 11.9 19.0 11.6 10.6 9.5 9.0 9.9 8.9 12.1 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788555-49835030 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 15.8 14.3 16.9 16.2 25.9 44.4 17.5 37.0 35.0 19.5 17.3 23.8 17.9 13.1 27.3 18.6 18.8 19.5 14.6 25.3 16.8 21.8 18.7 11.3 13.9 15.3 17.0 23.6 21.9 13.6 44.4 19.8 19.8 21.9 20.4 14.9 20.8 18.9 23.3 31.7 22.7 14.7 21.8 17.9 15.8 15.5 63.7 19.1 25.9 28.6 14.5 20.6 22.7 17.4 13.0 12.7 15.2 11.4 20.6 20.7 14.2 13.0 18.4 17.8 12.5 8.4 11.2 21.6 11.4 13.3 20.5 14.7 28.4 9.3 15.0 18.5 12.1 11.5 17.0 11.9 24.2 16.3 16.8 17.8 13.4 11.8 12.6 18.2 14.8 10.6 11.9 18.4 23.0 15.1 19.7 14.9 19.1 19.9 25.8 13.1 44.3 16.1 16.3 28.5 12.9 9.6 14.8 19.4 16.5 11.6 7.0 10.7 25.6 16.1 9.0 26.0 14.1 11.3 14.7 21.9 23.9 17.6 11.8 10.9 16.2 15.2 11.0 15.1 16.9 8.9 20.7 13.0 16.3 17.1 12.7 12.2 20.6 16.2 13.1 20.6 11.4 6.6 14.3 14.2 16.9 25.9 37.0 35.0 16.8 21.8 17.0 23.6 21.9 19.1 KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31115754-31131393 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 17.8;neutrophil: 17.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm Nucleoplasm "HPA066324: " "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favourable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" 18.4 21.7 22.7 29.4 23.6 26.6 29.7 48.9 30.8 28.0 24.8 18.3 27.5 15.7 29.8 48.3 16.7 35.0 28.2 32.7 23.0 21.2 20.8 18.9 26.3 29.0 20.2 21.0 52.8 31.4 38.0 22.2 31.5 16.8 21.2 17.7 22.1 35.1 26.2 39.8 22.1 19.7 25.9 20.5 27.4 18.6 27.3 18.4 30.2 31.7 22.6 22.2 20.2 26.6 2.1 4.1 17.8 4.6 1.7 2.9 1.9 7.6 11.8 14.8 4.4 17.6 13.2 15.2 6.8 13.1 11.0 12.1 5.9 16.7 18.1 10.8 8.5 9.1 23.6 11.5 10.9 15.1 16.0 7.8 8.7 18.7 15.8 12.9 14.2 12.4 23.1 8.2 23.8 10.5 20.8 14.9 5.6 22.3 19.9 24.4 16.7 7.2 32.1 12.1 21.2 8.9 4.6 15.6 15.8 4.1 11.5 5.8 12.5 21.5 6.2 4.7 9.9 5.2 4.9 14.2 14.3 10.2 7.1 17.3 7.0 3.9 4.4 17.8 1.9 2.4 2.4 2.1 2.2 2.6 4.1 1.8 2.9 2.1 17.4 1.7 4.6 1.4 1.3 1.9 22.7 23.6 48.9 30.8 23.0 21.2 20.2 21.0 16.8 18.4 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819148-50823787 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "pancreas: 742.6;salivary gland: 473.0" "Cell line enriched" "Detected in some" 23 "RPMI-8226: 28.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 20.0;pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 10.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 14 "B-cells: 10.9" "Secreted to digestive system" 4300000 "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.2 2.5 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.8 0.1 0.1 0.1 0.1 0.1 0.1 742.6 0.0 0.1 0.1 0.1 0.2 1.9 0.1 473.0 0.1 0.1 1.8 0.6 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.2 0.2 0.2 0.1 0.1 10.9 0.7 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 10.9 0.0 0.0 0.2 3.8 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell line enhanced" "Detected in many" "NB-4: 9.9" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA000764 Supported "Secreted in male reproductive system" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.8 4.9 0.5 0.3 0.2 0.2 0.6 0.7 1.8 0.2 0.0 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.4 0.3 0.3 0.4 0.0 1.4 1.9 0.3 1.8 1.2 9.9 1.1 0.0 0.9 0.0 2.8 0.0 1.6 0.9 1.5 0.3 1.3 1.3 1.2 0.4 0.8 1.3 1.9 4.8 1.6 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718256 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 15.4 12.9 17.6 12.5 17.6 19.4 14.7 38.4 16.9 15.9 13.6 17.4 9.5 10.1 17.7 11.8 12.2 14.6 11.1 11.7 15.1 8.8 11.5 11.1 12.7 12.6 18.2 8.8 23.6 12.2 22.3 21.8 17.2 15.5 16.3 12.5 14.1 13.8 11.9 12.4 12.8 14.7 15.8 13.0 13.5 11.6 10.6 19.6 20.5 12.9 6.5 12.8 14.7 14.7 7.4 4.6 9.5 11.4 4.2 8.9 2.9 6.1 4.8 10.2 14.4 9.6 12.6 7.8 8.1 8.2 8.8 8.8 7.8 5.3 9.9 8.3 11.3 8.6 13.3 8.7 13.9 9.1 10.6 20.0 6.1 7.0 8.9 18.7 14.6 8.4 14.0 9.9 17.0 10.9 24.6 10.2 8.6 7.3 9.7 7.7 6.0 4.7 9.5 12.2 4.6 8.1 8.7 6.8 10.9 11.4 8.3 6.0 8.6 16.2 13.4 7.0 11.0 8.3 13.0 8.5 9.3 11.4 6.4 10.6 10.3 9.5 4.2 6.6 8.9 7.7 8.0 5.8 7.0 7.4 4.6 7.4 6.0 7.8 2.9 4.2 11.4 4.1 6.7 2.9 17.6 17.6 38.4 16.9 15.1 8.8 18.2 8.8 15.5 19.6 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973032-21061547 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA039191: , HPA049037: " "unprognostic (2.77e-1)" "prognostic unfavourable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 22.9 13.0 3.0 8.6 5.7 12.8 33.0 7.9 3.7 16.6 14.0 6.8 9.3 2.9 21.2 12.7 15.1 11.0 20.6 14.1 5.4 2.6 12.4 11.0 19.8 10.9 5.2 2.4 17.4 10.2 5.0 3.5 18.3 6.3 13.7 4.5 16.7 8.0 11.1 23.0 9.3 7.4 34.6 7.5 15.2 10.4 27.8 5.2 1.4 17.2 13.8 7.0 20.3 28.0 0.1 1.5 3.3 1.9 1.3 3.1 0.5 3.3 3.7 8.3 5.0 9.8 12.9 7.6 11.2 11.7 11.8 10.1 10.6 5.1 0.0 5.5 17.1 4.9 4.9 5.1 17.5 1.9 1.2 6.2 4.7 7.9 15.3 1.6 2.2 19.1 9.4 7.7 5.2 16.4 1.1 0.2 14.8 5.8 0.1 5.8 2.0 1.8 1.4 14.8 0.0 8.4 1.6 0.1 0.0 8.8 5.8 11.6 5.0 3.2 20.6 12.5 8.4 9.1 7.1 1.5 0.8 0.0 3.0 1.9 9.5 0.4 1.9 1.8 1.6 1.5 3.1 0.1 0.2 0.5 1.5 0.0 0.1 0.3 3.3 1.3 0.6 0.1 0.0 0.5 3.0 5.7 7.9 3.7 5.4 2.6 5.2 2.4 6.3 5.2 LCT ENSG00000115850 Lactase P09848 2 135787840-135837180 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "intestine: 255.5" "Group enriched" "Detected in some" 5 "MOLT-4: 6.8;RPMI-8226: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Region enriched" "Detected in single" 16 "hippocampal formation: 17.3" "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 209.8 0.0 0.0 67.7 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 255.5 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 6.8 1.1 0.0 0.0 1.6 0.0 13.6 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.1 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.2" "Cell line enhanced" "Detected in all" "U-87 MG: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028064, HPA028516" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles, Cytosol" "HPA028064: AB_10600111, HPA028516: AB_10601751" "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavourable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavourable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavourable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 8.8 8.6 31.6 18.2 18.6 6.3 7.4 14.3 44.1 11.5 6.6 7.1 6.6 6.9 7.3 5.3 6.4 6.0 10.8 6.3 26.8 32.9 5.2 2.6 12.5 22.0 33.4 22.2 12.1 8.1 4.0 7.2 8.0 45.2 6.1 4.7 4.8 18.1 9.6 10.9 6.8 7.2 7.6 10.8 18.4 7.8 10.4 6.5 4.3 7.5 3.7 18.1 14.1 7.2 4.6 8.6 3.8 7.7 6.9 2.4 3.1 17.2 13.5 10.3 17.1 13.6 18.5 7.5 10.7 10.3 8.7 9.7 7.8 17.0 10.7 4.8 13.1 10.4 3.8 6.6 3.3 18.5 6.7 7.9 4.6 8.9 15.6 6.0 29.0 18.2 5.9 7.0 3.7 12.9 5.3 3.4 10.8 15.1 5.1 10.8 19.5 8.4 7.5 16.0 6.7 9.6 3.7 4.1 9.4 6.9 16.5 8.6 5.2 5.4 15.3 13.9 12.9 35.7 17.1 3.9 4.3 19.5 51.4 4.4 9.4 0.1 6.5 3.8 2.4 7.7 1.8 4.6 0.6 1.5 8.6 2.4 0.2 0.7 0.7 6.9 4.7 0.8 0.4 3.1 31.6 18.6 14.3 44.1 26.8 32.9 33.4 22.2 45.2 6.5 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 37.8;hTCEpi: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 14.7;neutrophil: 37.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB019313: , HPA008183: AB_1079252, HPA053882: " "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 9.4 6.6 23.5 23.6 26.2 29.4 17.0 9.9 16.8 11.0 20.9 15.6 10.7 13.1 12.9 8.7 33.7 22.1 28.7 6.0 15.4 10.7 15.4 19.9 21.6 18.1 20.8 7.2 11.4 19.9 20.0 12.8 64.3 23.3 17.1 22.1 10.1 25.7 16.2 9.7 36.7 13.3 10.1 28.3 17.4 18.5 16.8 17.9 12.4 25.8 15.6 15.3 13.1 20.0 1.0 1.6 37.2 1.9 2.4 5.6 1.6 7.0 1.1 4.9 2.7 2.1 2.5 37.8 4.7 2.2 4.7 4.0 6.1 3.3 6.9 8.4 7.0 14.4 5.7 24.6 3.0 5.0 6.2 5.0 5.6 6.5 3.2 9.2 9.2 4.0 70.1 3.8 11.5 12.0 2.8 5.0 6.4 5.5 5.6 3.2 4.6 1.8 7.5 8.3 3.8 5.5 16.8 6.3 5.7 3.5 22.7 9.4 18.9 3.7 7.2 4.2 6.6 2.3 4.3 2.8 4.1 6.0 2.7 4.4 1.8 2.1 1.9 14.7 1.3 1.3 2.4 0.8 2.3 1.7 0.7 1.0 2.3 1.8 37.2 2.4 0.5 1.6 5.6 1.6 23.5 26.2 9.9 16.8 15.4 10.7 20.8 7.2 23.3 17.9 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 103.5;fHDF/TERT166: 157.7;HSkMC: 38.5;U-138 MG: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043930 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" 290000 "Endoplasmic reticulum" "HPA043930: " "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavourable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavourable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavourable (3.32e-4)" 33.8 1.8 1.0 7.2 1.2 0.0 37.4 0.9 0.9 16.1 11.7 0.1 4.1 3.8 6.3 20.1 11.1 7.6 12.8 21.4 1.2 1.3 6.5 2.4 20.6 4.3 0.9 1.1 15.7 6.0 0.8 1.5 14.8 1.6 11.2 3.0 3.2 3.4 3.5 12.7 11.3 4.5 9.5 1.5 7.7 4.0 10.6 0.1 0.7 10.8 4.2 2.7 36.9 10.4 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.1 0.0 0.2 0.1 18.0 21.3 0.0 103.5 21.8 8.0 28.2 0.1 0.0 0.0 2.4 157.7 0.0 0.4 0.2 17.2 0.0 0.3 0.0 2.0 0.8 22.8 0.0 0.0 38.5 0.4 13.3 0.5 10.0 0.0 0.0 9.3 0.0 0.0 0.0 0.7 0.3 0.0 0.8 0.0 0.4 0.0 0.0 0.5 7.3 0.0 0.6 0.0 0.0 0.8 52.4 3.5 31.0 1.4 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.0 1.2 0.9 0.9 1.2 1.3 0.9 1.1 1.6 0.1 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23297189-23425328 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 107.9;BJ hTERT+ SV40 Large T+ RasG12V: 62.4;fHDF/TERT166: 69.9;TIME: 58.2;U-87 MG: 108.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "pons and medulla: 22.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Nucleoplasm "CAB025848: , HPA036257: , HPA056542: " "unprognostic (9.48e-2)" "prognostic unfavourable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavourable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavourable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavourable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavourable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 37.8 2.7 1.2 14.5 1.6 0.6 22.4 2.9 1.6 16.9 18.4 1.0 12.2 5.8 11.8 9.1 11.5 4.1 5.4 7.2 1.2 1.3 4.3 4.1 6.2 7.5 1.9 0.7 15.6 4.4 1.3 2.2 38.0 22.7 8.4 3.8 1.6 5.6 9.7 6.2 4.3 10.7 27.3 10.9 8.3 7.7 4.1 0.7 1.6 4.3 8.0 8.6 19.1 6.4 1.9 1.3 3.0 0.7 2.1 2.8 0.7 6.2 16.6 5.0 4.0 13.7 22.7 2.2 107.9 34.9 49.5 62.4 0.1 0.4 1.2 0.8 69.9 5.2 0.2 9.2 26.2 0.2 0.9 0.0 2.3 0.1 27.8 0.0 0.4 20.1 0.4 18.4 2.4 41.3 0.0 0.2 16.3 3.4 0.0 0.1 3.2 2.6 0.2 4.1 0.0 14.4 0.0 0.1 1.3 13.5 0.7 0.9 0.1 0.1 58.2 46.1 12.2 18.7 14.2 0.4 0.0 3.3 108.2 0.1 47.9 1.9 0.7 3.0 1.6 0.3 0.8 1.9 0.6 1.3 0.5 0.9 0.8 2.8 1.6 2.1 0.6 1.3 0.2 0.7 1.2 1.6 2.9 1.0 1.2 1.3 1.9 0.7 22.7 0.7 LRRK1 "FLJ23119, KIAA1790, RIPK6, Roco1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919215-101078254 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.3" "Cell line enhanced" "Detected in many" "Daudi: 23.1;Karpas-707: 17.0;U-266/84: 15.4;U-698: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.2;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA010537: AB_1079283" "unprognostic (3.74e-2)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-1)" "unprognostic (6.68e-2)" "unprognostic (6.35e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (3.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.95e-2)" "unprognostic (8.50e-2)" "prognostic unfavourable (5.71e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.25e-2)" 6.1 1.9 4.5 26.3 3.9 6.5 5.0 2.1 8.1 6.4 8.0 5.9 2.2 2.9 7.9 6.0 5.4 7.1 4.2 3.4 4.0 1.5 2.7 1.0 4.7 15.0 4.5 4.0 6.3 5.3 2.8 2.3 4.4 2.5 7.1 6.5 2.8 7.7 6.8 1.6 7.3 8.5 5.7 3.7 11.1 3.9 5.1 3.4 1.2 3.5 2.1 17.4 7.5 6.7 2.3 3.3 3.2 1.1 0.0 0.0 0.1 0.8 4.7 0.0 0.0 7.3 7.5 0.0 2.8 2.1 2.6 1.8 0.8 2.1 23.1 1.0 7.7 4.7 0.6 0.5 1.3 0.4 1.1 7.0 1.0 0.0 0.5 3.7 5.4 5.9 1.0 1.7 1.5 4.7 1.1 17.0 0.5 0.0 0.0 2.3 0.2 2.0 1.6 0.4 6.3 0.0 0.0 0.0 1.6 1.8 2.7 5.3 0.3 4.5 5.4 0.0 0.8 1.0 0.0 8.7 15.4 15.0 0.3 0.5 4.3 0.0 0.7 3.2 0.0 0.3 0.0 2.3 0.0 0.0 0.9 1.5 0.0 0.0 0.8 0.0 1.1 3.3 0.0 0.1 4.5 3.9 2.1 8.1 4.0 1.5 4.5 4.0 2.5 3.4 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell line enhanced" "Detected in some" "A549: 9.7;ASC TERT1: 10.0;BJ hTERT+: 5.6;RPTEC TERT1: 10.7" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favourable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.7 0.1 0.0 3.9 10.0 0.1 2.1 5.6 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.4 0.0 0.7 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 0.6 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.6 0.0 0.2 2.7 2.8 2.2 1.4 1.1 1.1 1.2 0.7 0.0 0.0 0.0 2.3 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 LRSAM1 "CMT2P, FLJ31641" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451486-127503501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favourable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favourable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 9.5 13.6 15.6 10.1 17.2 15.3 9.2 24.2 22.6 10.7 18.0 15.3 10.9 10.8 12.6 17.6 12.3 11.0 11.9 18.7 13.3 17.3 11.2 15.6 11.7 11.5 13.5 22.7 16.0 9.6 17.6 11.8 9.2 17.9 13.6 8.6 10.2 11.9 13.7 20.4 28.3 11.1 16.0 18.7 12.6 12.2 6.1 13.9 5.5 11.6 9.6 11.5 17.2 12.9 4.1 5.4 17.4 6.6 1.3 4.8 3.2 5.7 8.7 5.3 10.1 8.9 8.8 8.3 5.4 6.7 8.3 6.2 10.0 5.6 9.8 5.5 7.5 18.9 6.4 11.3 3.3 10.4 4.9 5.3 11.3 8.7 7.1 5.8 11.2 5.1 9.3 5.7 10.9 8.9 4.7 10.2 3.6 14.4 4.1 5.1 5.0 8.8 6.7 4.7 15.3 9.0 5.0 9.7 8.0 3.5 12.0 7.0 24.6 3.1 10.4 5.6 5.7 7.0 3.6 11.3 8.4 1.6 9.2 5.4 2.9 14.6 4.9 17.4 4.4 6.6 4.8 4.1 3.0 3.7 5.4 3.1 1.5 2.0 5.7 1.3 5.5 4.6 2.4 3.2 15.6 17.2 24.2 22.6 13.3 17.3 13.5 22.7 17.9 13.9 LRTOMT "CFAP111, COMT2, DFNB63, LRRC51" ENSG00000184154 "Leucine rich transmembrane and O-methyltransferase domain containing" "Q8WZ04, Q96E66" 11 72080331-72110782 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 49.8;testis: 47.8" "Cell line enhanced" "Detected in many" "T-47d: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favourable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" 3.5 3.7 10.6 2.0 11.1 2.1 7.1 3.7 8.9 7.1 4.2 14.0 6.1 3.2 6.0 13.6 3.5 49.8 5.3 2.6 8.8 7.6 9.0 6.2 6.2 2.6 7.7 8.5 8.5 7.0 7.1 8.9 4.4 10.6 7.5 6.2 7.3 4.3 4.7 5.2 4.5 2.5 4.8 7.7 3.2 3.6 47.8 8.9 3.1 9.3 2.4 3.5 3.5 2.6 4.3 4.2 9.2 2.9 10.1 6.2 2.0 2.6 9.8 6.2 5.0 5.4 4.8 1.5 3.1 2.5 2.8 2.5 4.7 14.3 3.4 4.8 5.3 5.3 4.4 7.5 3.2 6.4 4.3 2.5 4.5 3.3 0.9 2.0 2.7 2.1 3.8 4.3 3.3 1.0 2.7 5.3 4.1 9.4 6.0 4.0 3.1 2.6 7.3 6.3 5.2 11.0 3.2 5.8 4.5 6.1 14.1 7.5 27.8 2.4 4.7 3.0 4.2 8.0 2.1 5.7 6.2 4.0 2.9 1.7 3.3 2.3 2.9 5.0 3.1 2.8 3.2 4.2 3.3 2.6 1.7 4.3 3.0 3.0 9.2 10.1 1.8 4.2 6.2 2.0 10.6 11.1 3.7 8.9 8.8 7.6 7.7 8.5 10.6 8.9 MAK "dJ417M14.2, RP62" ENSG00000111837 "Male germ cell associated kinase" P20794 6 10762723-10838555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 38.1;testis: 19.3" "Cell line enhanced" "Detected in some" "HDLM-2: 4.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 7 "pons and medulla: 10.6" "Cell type enriched" "Detected in single" 13 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "unprognostic (1.23e-3)" "unprognostic (8.77e-3)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-3)" "unprognostic (1.97e-2)" "unprognostic (2.53e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (6.73e-2)" "unprognostic (6.59e-5)" "unprognostic (1.55e-1)" "unprognostic (8.40e-2)" "unprognostic (7.71e-3)" "unprognostic (4.59e-2)" 0.6 0.3 0.7 0.7 1.5 1.4 0.7 0.4 0.4 0.8 0.2 3.5 0.3 0.2 0.6 2.9 0.3 8.6 1.0 0.3 1.1 1.2 0.3 0.2 1.8 3.7 0.2 0.1 2.2 0.5 9.3 3.6 0.2 10.6 0.5 0.0 38.1 0.5 0.4 0.2 1.1 0.4 0.1 0.7 1.4 0.5 19.3 0.7 0.0 0.6 0.4 0.2 0.2 1.2 0.6 0.4 11.7 0.8 0.3 0.7 0.1 3.0 0.9 1.8 1.8 0.1 0.0 1.7 0.0 0.2 1.0 1.0 1.3 1.7 0.9 0.7 0.0 0.5 0.6 0.3 0.4 4.7 1.9 0.7 0.7 1.2 0.0 3.2 2.9 0.1 0.0 0.2 0.3 0.0 1.6 0.6 0.1 0.4 0.4 1.9 0.8 0.4 0.6 0.8 0.3 0.1 0.4 1.9 0.9 0.1 0.5 0.1 1.1 0.3 0.2 0.7 1.1 0.2 1.1 0.5 0.1 0.4 0.5 0.6 1.0 0.5 0.8 0.9 0.4 0.5 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.7 11.7 0.3 0.8 0.4 0.1 0.1 0.7 1.5 0.4 0.4 1.1 1.2 0.2 0.1 10.6 0.7 MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350541 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 29.9;RPTEC TERT1: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 24 "neutrophil: 37.5" "Lineage enriched" "Detected in many" 36 "granulocytes: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" 28000000 "Golgi apparatus, Vesicles" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favourable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" 13.1 8.8 9.7 5.1 13.7 4.2 14.7 10.1 18.4 13.5 17.8 7.5 12.9 13.4 15.1 14.1 27.3 11.2 19.3 7.9 9.2 7.6 9.5 7.6 8.4 6.6 6.9 9.0 11.3 26.4 18.5 19.5 11.0 9.0 15.0 18.5 12.8 42.6 15.2 3.6 13.3 13.3 14.4 5.8 8.4 21.3 9.1 6.2 0.0 9.5 16.7 18.2 12.6 12.9 0.2 0.2 37.5 0.5 0.2 1.0 0.1 0.2 3.3 1.0 0.0 3.4 3.3 3.6 2.3 2.7 1.2 1.5 2.7 10.7 0.0 2.5 2.2 0.4 4.2 1.9 0.9 0.0 3.8 4.7 4.1 2.2 0.6 0.7 1.4 2.1 3.1 0.7 0.5 29.9 3.0 0.0 0.4 6.2 0.0 0.3 3.7 1.8 0.1 0.0 0.1 15.5 10.9 1.4 5.9 1.2 10.0 3.4 9.0 3.0 11.7 1.7 1.4 0.4 3.1 0.2 0.1 1.6 1.2 0.0 1.2 1.5 0.5 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.2 1.0 0.1 37.5 0.2 0.1 0.0 0.0 0.1 9.7 13.7 10.1 18.4 9.2 7.6 6.9 9.0 9.0 6.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.1 15.6 31.5 13.1 19.0 14.3 18.2 24.1 20.6 26.2 23.4 23.5 27.3 30.5 29.9 19.8 29.6 29.4 35.2 30.8 24.5 17.5 9.8 16.4 12.7 15.4 12.9 14.6 11.0 21.8 18.9 28.1 20.4 17.3 39.0 38.1 12.8 10.3 16.8 16.1 13.7 11.7 19.5 27.1 25.4 14.3 19.4 10.8 19.5 15.3 20.2 13.8 11.0 28.1 34.1 20.9 24.0 35.7 24.2 43.0 19.4 36.0 22.8 15.9 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol Cytosol "CAB003835: AB_562312, HPA051993: " "unprognostic (4.39e-1)" "prognostic favourable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favourable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favourable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.2 40.0 21.9 30.7 30.3 36.6 21.9 23.9 32.0 32.7 29.7 34.6 19.7 31.0 22.6 27.2 26.2 17.1 25.5 25.4 26.3 20.8 11.3 21.8 38.2 46.5 20.8 23.9 40.4 24.9 22.9 30.6 28.9 21.6 61.3 27.5 45.4 41.1 29.2 25.1 29.1 31.5 14.4 35.4 28.5 23.3 29.7 29.6 21.9 30.4 74.5 23.4 35.7 25.5 26.9 23.3 68.6 36.8 61.7 37.3 21.7 41.7 37.5 45.9 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.6 22.0 2.9 13.3 17.8 11.4 11.1 33.6 36.5 26.8 24.7 24.3 14.0 19.6 13.7 52.5 21.5 9.3 29.8 19.1 20.3 17.0 11.4 12.6 22.0 5.5 14.9 23.4 8.8 8.5 36.5 11.0 12.0 2.2 9.8 22.3 21.5 7.4 14.2 8.4 12.6 15.5 18.9 14.5 15.1 22.9 8.0 2.8 12.4 13.4 23.3 6.7 5.1 10.9 25.5 20.8 27.2 21.6 12.3 6.2 25.2 24.6 12.9 13.1 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 17.9 15.5 20.4 10.5 11.3 14.7 13.0 12.3 16.2 14.0 13.4 9.2 6.2 7.5 10.0 19.1 12.1 17.7 17.1 21.1 13.2 20.8 8.3 9.1 17.3 13.3 7.9 12.6 12.1 17.0 16.4 17.2 12.7 8.8 4.4 17.6 6.7 9.6 7.4 11.9 7.6 11.8 22.9 5.1 19.2 11.6 4.1 12.1 14.2 7.6 11.8 9.6 5.8 11.6 6.9 10.7 9.5 14.5 8.7 9.7 5.9 13.0 6.3 10.0 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favourable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.5 14.6 8.8 10.3 13.0 22.8 6.9 5.5 11.2 10.4 11.4 5.8 9.9 9.1 11.7 9.2 8.3 14.9 8.8 8.6 13.1 14.9 12.3 10.9 6.3 16.4 7.4 7.7 15.6 11.7 7.5 17.1 13.7 10.8 15.2 8.6 7.1 12.1 8.8 12.3 7.1 12.0 10.2 15.1 6.3 10.1 5.5 8.6 6.2 9.2 22.0 11.5 14.6 11.4 10.7 7.1 7.4 7.4 21.5 25.3 10.6 14.4 17.0 7.7 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell line enhanced" "Detected in many" "A549: 23.9;HUVEC TERT2: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favourable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favourable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 23.9 10.8 13.0 4.7 2.5 1.6 0.1 3.5 1.0 1.5 0.7 1.1 0.6 8.8 0.5 1.2 3.7 0.5 0.3 0.8 1.9 0.1 6.7 6.7 4.6 1.0 0.9 11.9 0.3 0.3 0.0 17.2 0.0 1.7 0.0 0.1 12.5 0.4 7.6 4.4 4.5 1.1 0.3 4.8 3.3 4.8 7.3 1.0 0.9 2.2 3.3 1.3 3.0 1.3 1.5 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: " "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favourable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favourable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.7 7.3 6.4 10.4 5.1 5.0 11.9 8.4 4.1 5.7 6.0 10.5 7.8 15.2 13.6 4.4 11.7 5.5 6.4 2.2 12.1 27.4 10.7 9.7 7.8 6.6 9.9 13.6 5.7 8.4 4.5 5.2 5.2 15.6 20.0 3.3 6.7 14.2 24.2 11.2 16.5 14.1 6.9 15.4 5.1 10.7 11.7 11.8 5.7 10.1 11.7 10.8 11.4 7.7 17.5 10.0 12.3 11.3 29.0 13.4 14.3 8.7 14.7 7.0 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.0;THP-1: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol Cytosol "CAB004500: AB_627926, HPA046509: " "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.4 3.9 6.2 4.1 1.0 0.8 10.4 1.2 1.7 3.9 5.5 18.4 4.9 5.8 0.4 1.5 3.4 5.1 2.3 5.4 2.0 2.2 3.2 1.7 8.6 2.5 5.1 9.0 1.0 2.5 1.2 1.9 1.7 2.8 10.5 1.0 2.8 3.5 6.9 2.8 0.5 5.6 4.4 19.9 6.8 6.8 2.6 27.0 3.8 4.8 11.0 13.2 25.2 4.9 0.3 3.3 1.4 2.3 7.7 3.9 11.1 0.6 3.0 6.6 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191744-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favourable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favourable (2.13e-4)" 7.7 7.0 29.6 4.7 22.8 3.7 2.2 14.3 32.0 3.3 3.4 5.3 1.8 4.4 4.5 1.8 3.7 3.1 4.0 8.2 28.2 11.2 4.7 2.1 4.2 4.6 11.5 9.4 4.3 8.1 4.7 5.2 3.7 9.0 4.6 2.0 2.4 6.9 4.8 22.9 5.6 5.0 4.0 5.3 6.7 6.2 6.6 7.1 2.3 3.3 2.6 2.4 3.8 5.4 0.8 0.0 0.0 0.2 0.0 0.9 0.0 6.2 7.5 2.3 5.5 2.2 1.3 6.5 4.4 2.2 2.0 2.1 1.7 1.8 5.7 4.6 1.5 2.0 0.9 2.2 0.3 10.9 7.1 1.5 3.2 1.7 4.2 1.2 3.7 1.2 5.4 2.2 1.5 1.9 5.4 9.8 0.6 3.7 4.7 2.3 2.8 4.9 5.9 2.5 3.4 1.8 4.0 7.8 11.3 5.1 1.8 10.3 2.5 2.3 3.1 5.3 5.1 7.8 8.4 13.0 7.5 2.5 6.2 2.4 7.7 0.0 0.1 0.0 0.4 0.2 0.0 0.8 0.2 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 29.6 22.8 14.3 28.7 28.2 11.2 11.5 9.4 9.0 7.1 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597755-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 75.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 23.2 10.8 11.4 23.7 21.2 14.2 27.4 7.9 13.8 8.6 15.8 29.8 6.1 31.9 11.0 8.1 14.7 11.6 12.0 11.6 13.3 8.1 16.1 31.2 21.1 14.4 30.9 8.2 8.4 12.5 8.3 10.3 14.7 16.7 13.4 8.2 15.4 13.5 9.5 11.9 13.7 31.9 8.6 17.7 28.8 16.9 8.6 19.0 8.9 13.6 7.6 12.7 8.9 75.8 2.3 7.6 13.8 12.0 1.8 3.5 5.6 16.5 14.6 7.9 8.4 2.5 3.2 8.1 6.4 4.5 7.7 5.3 14.6 16.0 6.2 23.7 5.0 14.4 4.7 6.9 2.8 13.6 6.0 17.5 10.0 17.4 7.0 10.0 26.5 5.0 6.7 5.7 5.2 21.5 7.5 12.5 4.0 20.4 11.7 18.9 8.6 18.7 19.5 5.1 12.6 7.2 14.3 7.1 8.0 7.5 21.8 37.5 17.4 16.3 23.9 11.8 12.8 17.2 11.3 8.0 9.0 5.5 13.8 11.6 27.3 4.3 7.7 9.2 2.4 12.0 2.4 2.0 2.6 3.5 7.6 2.3 2.0 1.5 13.8 1.8 11.7 2.3 1.4 5.6 11.4 21.2 7.9 13.8 13.3 8.1 30.9 8.2 16.7 19.0 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell line enhanced" "Detected in many" "ASC diff: 28.4;HHSteC: 27.1;HSkMC: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 3.4;monocytes: 1.7;T-cells: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "HPA039936: AB_10795239, HPA071996: " "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favourable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavourable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 8.0 8.7 12.3 5.8 16.0 3.0 5.1 40.3 20.6 14.1 6.1 7.0 7.8 3.6 15.1 5.8 4.6 11.5 16.1 4.2 9.4 7.7 4.5 1.4 8.8 4.5 6.4 14.7 13.7 1.8 3.0 12.7 7.3 10.8 5.9 4.6 9.5 2.4 13.5 1.2 4.5 4.1 16.9 5.3 5.3 3.9 6.5 7.4 2.7 4.3 1.4 3.2 11.3 6.4 0.3 0.6 3.4 1.7 0.6 2.8 0.5 0.2 7.5 4.7 7.3 28.4 15.2 0.6 5.1 9.6 5.6 5.6 0.1 0.9 1.7 2.9 5.4 0.0 2.1 3.4 2.2 2.5 2.6 1.8 3.8 0.0 27.1 0.0 1.9 27.0 2.4 7.6 4.0 8.7 0.0 8.1 5.3 3.3 1.8 0.4 1.6 2.8 2.6 3.2 0.4 2.8 0.0 4.7 6.4 2.7 3.5 7.2 2.4 4.7 6.4 5.4 5.8 2.4 1.3 3.3 3.7 0.0 8.7 3.3 5.2 0.0 1.7 0.0 1.5 1.3 2.8 0.3 2.1 2.3 0.6 0.0 0.9 1.2 3.4 0.6 0.4 0.3 0.4 0.5 12.3 16.0 40.3 20.6 9.4 7.7 6.4 14.7 10.8 7.4 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489097 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavourable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favourable (1.11e-4)" "prognostic unfavourable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 9.8 24.8 21.7 8.7 22.2 9.5 15.1 16.4 26.1 12.9 16.9 18.4 10.5 16.8 12.9 42.1 15.2 14.6 13.1 8.1 19.2 18.6 21.9 20.7 15.2 7.4 23.2 17.1 16.5 24.9 20.9 24.5 9.1 21.8 14.5 18.9 18.6 26.2 11.4 3.3 9.8 23.4 12.1 26.4 8.7 16.4 12.9 15.8 4.4 18.6 8.3 10.3 12.5 11.5 23.7 21.5 21.1 13.2 11.5 17.4 7.8 29.1 5.8 11.3 0.3 10.3 12.7 6.6 6.7 4.6 10.9 13.2 11.2 11.0 0.2 23.0 12.2 16.7 0.3 15.5 19.4 32.4 15.0 0.1 7.9 9.2 11.2 15.3 8.4 11.5 13.6 9.3 11.7 12.1 0.3 23.7 9.7 9.1 1.8 7.2 13.0 13.7 0.2 13.5 16.0 19.2 7.6 18.6 12.4 11.3 17.1 23.2 25.8 8.6 8.0 9.0 11.7 16.2 14.5 12.1 15.6 9.6 13.2 7.8 14.7 6.4 13.2 5.1 10.3 12.2 15.8 23.7 12.4 12.8 21.5 19.0 17.4 16.8 21.1 11.5 8.6 9.4 4.8 7.8 21.7 22.2 16.4 26.1 19.2 18.6 23.2 17.1 21.8 15.8 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263121-45317040 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 22.0;HDLM-2: 22.6;U-251 MG: 22.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_10600302, HPA027270: AB_10600884" "unprognostic (1.05e-2)" "prognostic favourable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 3.7 3.4 3.0 14.7 4.0 3.4 2.7 4.9 3.6 5.0 7.3 4.5 3.5 6.0 5.5 3.3 6.8 4.2 6.2 4.5 3.0 4.4 5.1 4.9 12.0 3.0 0.6 3.5 5.7 3.5 7.7 1.5 4.6 5.2 3.5 4.3 7.5 4.8 14.5 6.1 9.6 5.2 4.1 8.4 4.0 4.5 4.5 7.1 2.2 6.9 18.0 4.9 2.8 9.5 4.8 7.7 3.6 5.6 5.2 2.3 9.4 22.0 2.2 3.9 1.5 3.7 5.6 2.6 1.8 8.3 5.1 3.4 11.6 4.2 13.3 2.7 6.6 1.0 3.5 4.3 22.6 1.7 0.9 6.0 1.5 4.0 0.7 4.4 5.8 2.2 4.1 2.2 1.6 1.8 18.0 4.2 3.4 3.9 1.5 1.2 3.1 5.2 6.7 9.5 6.0 1.9 2.3 1.9 4.0 2.7 2.8 1.7 0.4 3.5 3.8 5.9 3.2 22.1 17.2 6.4 2.2 2.1 2.4 5.1 1.5 3.4 1.6 3.5 3.6 2.0 7.6 2.4 2.5 2.3 9.5 2.6 2.5 7.7 5.6 2.2 4.8 5.2 2.3 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 13.2" "Cell line enhanced" "Detected in some" "A549: 3.4;HAP1: 8.6;HEK 293: 7.2;HEL: 2.9;REH: 4.4" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "pons and medulla: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004006 Approved Vesicles Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.1 17.3 0.5 0.4 0.3 0.5 0.1 2.3 0.1 0.1 0.1 5.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.5 3.6 0.1 0.5 0.0 0.1 0.0 1.3 4.1 0.4 5.7 0.0 13.2 0.1 0.0 4.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 2.6 0.1 2.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.4 7.2 2.9 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.2 2.2 0.9 4.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.3 0.1 0.4 0.5 0.1 0.0 13.2 0.0 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021540: " "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 18.5 14.5 13.7 20.1 14.5 41.0 22.6 20.1 16.3 16.6 19.6 12.7 18.9 18.8 19.8 18.0 13.4 15.9 18.6 13.3 12.5 10.2 15.5 27.6 20.0 28.5 17.9 13.0 20.3 15.4 23.8 21.2 13.9 12.3 13.6 13.1 12.2 18.1 25.5 24.5 19.4 22.5 18.1 14.9 17.0 18.0 14.9 14.3 25.8 22.5 13.7 16.8 17.1 20.3 3.1 5.1 13.6 2.9 2.3 2.1 1.1 16.3 7.0 5.6 5.6 7.8 10.4 9.3 10.2 11.1 10.1 8.2 8.3 7.3 10.8 17.6 14.5 13.9 8.9 6.8 11.3 27.0 6.9 10.0 12.6 7.3 9.1 10.0 21.7 9.3 7.6 12.2 15.0 4.6 4.7 21.6 9.9 5.9 11.7 7.1 5.7 9.1 7.7 10.5 8.0 4.1 15.3 11.1 5.9 14.8 9.1 9.2 5.9 7.7 10.6 19.8 18.6 9.1 13.8 22.4 16.1 11.1 9.5 6.6 8.5 4.0 2.9 2.0 1.7 1.8 2.1 3.1 1.6 1.7 2.4 2.6 1.9 2.0 13.6 2.3 2.2 5.1 1.4 1.1 13.7 14.5 20.1 16.3 12.5 10.2 17.9 13.0 12.3 14.3 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268010 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 96.1" "Cell line enhanced" "Detected in many" "U-138 MG: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 13.7" "Group enriched" "Detected in many" 5 "dendritic cells: 13.7;monocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 21.7 5.0 2.9 7.4 3.3 0.8 9.2 2.8 3.1 25.7 24.8 2.1 10.7 3.1 30.2 15.4 26.2 13.1 14.9 52.5 3.5 3.0 2.4 8.5 7.5 2.5 4.5 3.0 21.7 4.4 22.6 3.1 6.9 4.2 25.6 5.4 11.5 6.7 15.8 96.1 5.8 8.0 68.4 4.7 3.7 15.8 6.6 3.5 2.8 6.7 38.0 4.9 46.7 24.0 2.1 13.7 2.3 8.0 0.4 1.6 2.7 8.7 7.3 5.8 7.6 16.9 25.2 3.6 31.6 24.7 14.8 15.9 5.0 5.8 6.7 8.3 31.6 5.9 8.6 16.7 33.3 13.1 5.8 11.0 8.3 1.0 6.7 9.8 11.6 20.2 7.2 27.8 43.9 9.7 4.9 1.3 9.7 3.7 6.1 4.9 3.2 4.2 9.1 11.9 0.0 3.6 5.0 3.4 3.3 12.2 3.0 5.1 3.4 5.3 9.7 47.2 19.4 14.0 7.1 0.0 0.0 1.4 33.9 2.7 4.9 0.1 8.0 0.0 0.9 7.5 0.9 1.5 0.8 1.6 13.7 2.1 0.0 0.8 2.3 0.4 6.6 0.3 0.7 2.7 2.9 3.3 2.8 3.1 3.5 3.0 4.5 3.0 4.2 3.5 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327768-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.9" "Cell line enhanced" "Detected in many" "HEK 293: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.6 3.2 2.0 3.4 2.2 1.3 2.2 10.0 3.3 1.5 11.4 0.6 9.1 9.9 0.8 5.2 2.4 3.9 3.9 0.7 1.3 2.1 12.5 13.3 5.6 0.5 0.9 1.7 0.8 28.9 4.4 2.6 1.0 1.2 1.3 6.0 1.0 3.7 2.5 0.4 2.7 17.2 0.3 0.9 0.7 10.1 12.4 0.6 0.5 2.4 0.8 1.3 1.1 1.6 0.5 0.8 0.1 0.3 5.0 0.2 0.1 7.3 12.5 0.2 0.0 0.0 0.0 6.3 0.2 0.0 0.3 0.5 6.9 6.4 0.7 5.2 0.1 3.9 9.4 3.8 0.8 13.6 18.0 0.1 7.0 0.0 0.4 11.9 2.9 0.1 5.1 0.2 7.3 0.4 0.1 2.4 0.0 1.6 3.8 4.3 8.9 5.5 0.0 0.0 13.1 8.6 3.1 9.2 2.5 4.3 0.2 0.0 3.7 3.8 0.0 0.0 1.2 0.0 7.3 2.2 2.8 0.0 1.2 3.3 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.8 0.5 0.0 0.0 0.1 5.0 0.0 0.2 0.2 0.1 2.0 2.2 10.0 3.3 1.3 2.1 0.9 1.7 1.2 0.6 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm Nucleoplasm "CAB007764: AB_562314, HPA035410: , HPA035411: " "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.1 7.6 9.7 9.4 18.6 15.0 4.4 10.0 11.0 12.5 10.1 3.5 2.1 10.9 7.1 19.6 3.8 6.3 7.1 7.9 9.5 13.9 8.9 10.3 4.9 9.7 6.8 9.5 10.7 4.9 15.5 8.2 30.3 5.4 14.5 9.9 7.1 12.2 7.1 6.0 8.1 6.5 24.8 7.1 4.5 4.6 5.0 11.9 6.8 8.2 8.3 8.2 6.8 27.2 32.0 8.5 17.3 12.1 14.4 14.6 4.0 6.9 5.5 8.3 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.6 5.3 10.1 8.6 6.3 7.4 6.5 5.3 4.7 6.1 6.5 7.5 3.4 9.6 3.8 13.5 11.7 10.3 10.6 7.5 7.0 8.4 12.5 4.9 7.4 4.8 13.0 6.1 4.6 12.3 6.4 5.8 7.9 31.6 11.1 6.5 4.8 8.7 6.6 6.1 8.2 9.6 9.3 7.6 5.6 3.4 5.8 5.2 9.9 10.6 0.9 4.3 15.9 7.4 7.5 9.6 6.9 25.0 6.5 5.2 8.8 8.8 13.4 7.8 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557047-136792518 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 55.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol Cytosol "CAB007824: AB_598175, HPA063245: " "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favourable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavourable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 7.7 55.6 13.0 7.5 17.6 7.6 5.5 12.9 12.7 4.0 5.4 6.9 3.6 4.6 7.2 5.1 6.4 6.1 4.9 7.3 11.8 6.8 6.8 5.5 7.7 8.8 8.2 6.4 32.4 28.2 1.5 9.9 3.4 7.9 11.6 6.2 5.8 4.2 4.9 3.7 5.0 4.6 4.3 7.5 9.8 8.7 7.3 8.6 2.0 10.0 3.4 9.0 10.8 18.9 2.5 2.5 8.5 3.0 4.1 7.0 1.4 2.8 1.7 0.0 0.0 4.1 11.1 1.0 4.1 22.3 2.1 2.0 0.1 2.9 1.7 6.1 5.7 4.0 7.1 2.1 5.6 2.3 5.6 14.7 3.9 0.0 19.8 6.8 0.0 14.6 2.8 3.3 9.6 7.1 3.6 16.5 15.0 5.5 0.1 5.8 0.7 2.4 3.8 4.7 6.7 8.6 18.3 5.2 3.4 3.4 3.3 0.9 0.7 6.1 6.2 3.6 1.1 0.2 3.8 13.5 8.9 0.0 2.8 9.6 3.1 5.7 3.0 3.3 2.7 2.3 4.9 2.0 4.3 3.7 2.5 2.5 0.4 1.4 8.5 4.1 2.1 2.4 7.0 1.4 13.0 17.6 12.9 9.4 11.8 6.8 8.2 6.4 7.9 8.6 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366892 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: " "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.13e-4)" "prognostic favourable (7.26e-4)" "prognostic unfavourable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 37.5 6.3 7.4 6.9 8.6 1.3 22.1 12.6 8.3 19.9 9.0 2.7 8.9 3.3 13.1 10.3 25.7 12.8 12.4 14.9 6.2 2.6 13.6 5.0 21.7 5.5 11.4 1.9 11.7 8.3 8.2 15.8 7.3 9.8 13.9 5.9 15.7 11.5 9.7 6.3 63.9 6.2 16.0 11.7 8.7 9.0 6.7 7.0 0.6 12.0 16.1 14.3 14.3 18.3 2.7 3.3 5.1 6.9 1.1 7.6 2.4 7.4 6.9 6.2 6.9 8.7 15.3 1.6 9.3 5.4 7.0 5.3 2.0 10.0 0.1 8.3 14.1 11.8 2.1 6.5 3.5 6.2 5.1 0.5 16.0 3.1 2.7 0.5 0.6 12.2 15.9 7.3 2.6 4.7 2.3 4.1 11.1 18.4 0.3 8.4 1.9 5.7 2.7 4.1 1.7 10.5 7.8 2.3 3.4 9.8 8.6 7.3 4.6 6.4 9.8 17.6 7.4 19.7 4.8 3.3 4.1 0.1 15.6 6.1 5.1 1.8 1.5 5.1 5.3 3.3 7.6 2.7 5.5 5.9 3.3 2.3 4.4 3.6 2.4 1.1 6.9 0.0 5.6 2.4 7.4 8.6 12.6 8.3 6.2 2.6 11.4 1.9 9.8 7.0 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587045 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 15.5 17.6 19.6 17.3 26.3 10.3 21.6 27.5 27.3 21.1 16.4 15.7 15.8 12.5 23.1 23.6 15.2 15.5 17.6 22.2 20.5 17.5 15.9 15.5 20.0 22.2 22.9 16.4 25.0 13.5 25.8 25.6 23.6 20.7 21.2 15.3 12.4 17.0 23.3 24.3 18.7 14.7 19.4 23.0 23.3 14.7 13.8 21.7 28.2 20.3 10.8 21.9 17.2 18.9 14.2 15.9 19.4 17.7 18.2 22.1 13.6 7.7 6.9 20.1 17.2 14.7 19.7 14.2 15.6 18.1 14.1 17.8 8.8 7.5 17.3 10.0 16.9 8.3 12.6 12.2 24.0 8.8 13.4 15.4 9.5 11.7 15.4 17.1 11.9 16.2 14.9 13.7 16.9 13.2 30.8 14.2 20.1 9.5 7.9 14.5 16.5 8.7 13.7 36.1 8.4 11.8 8.7 10.2 14.5 10.9 7.6 11.8 7.5 30.5 12.6 11.5 7.3 10.5 14.5 12.7 11.3 7.5 17.6 18.8 16.8 15.5 12.7 19.4 15.1 17.4 16.8 14.2 14.5 14.4 15.9 10.5 16.5 16.0 12.5 18.2 17.7 9.8 22.1 13.6 19.6 26.3 27.5 27.3 20.5 17.5 22.9 16.4 20.7 21.7 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30433937-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.6" "Cell line enhanced" "Detected in many" "HMC-1: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavourable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 28.0 7.6 3.6 15.6 4.1 104.6 26.1 1.5 2.6 8.2 8.4 2.7 11.3 3.4 11.5 16.5 13.8 19.5 15.3 20.1 4.3 2.9 6.3 7.6 29.0 33.7 4.3 2.0 9.8 3.6 2.8 4.1 27.5 8.3 7.9 6.8 9.4 6.1 18.4 8.6 15.3 9.6 23.4 9.7 25.6 10.7 6.7 3.6 2.4 7.0 13.2 17.2 13.2 15.6 19.6 13.8 23.7 16.8 12.4 7.8 4.0 7.9 7.1 1.9 4.1 10.3 8.7 9.1 2.0 11.9 4.4 5.3 4.9 18.5 5.2 5.1 4.2 14.9 4.5 1.9 1.6 12.0 2.3 9.7 12.1 15.7 8.7 3.0 24.0 10.8 1.1 4.4 0.8 1.9 4.3 7.8 0.7 4.5 0.1 11.6 0.7 2.5 0.6 1.6 3.0 4.4 16.1 0.2 0.8 7.1 6.1 0.9 2.0 6.4 0.1 2.7 2.3 9.7 0.3 11.9 11.1 1.5 3.9 13.2 0.1 17.9 7.0 23.7 7.8 12.0 4.3 9.6 1.7 4.9 6.6 19.6 0.1 3.0 16.7 12.4 16.8 13.8 0.4 4.0 3.6 4.1 1.5 2.6 4.3 2.9 4.3 2.0 8.3 3.6 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell line enhanced" "Detected in many" "A-431: 17.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.5 2.2 5.8 2.0 9.2 1.4 2.8 20.1 16.5 2.4 3.1 1.8 0.4 3.0 1.1 3.4 10.1 2.2 1.5 1.2 5.7 7.1 3.1 2.4 3.9 2.6 5.9 5.9 1.4 4.3 6.8 4.7 2.8 12.8 2.0 3.1 3.1 3.2 1.3 1.9 7.8 2.9 0.7 1.6 1.9 3.4 10.1 1.8 0.6 5.3 3.2 6.8 2.0 3.9 2.3 0.5 1.3 0.2 1.1 1.4 0.3 17.7 8.2 1.6 2.0 0.0 0.0 5.5 0.3 0.2 1.7 1.5 5.9 6.8 3.6 2.4 0.1 8.4 5.2 10.0 1.8 2.4 1.5 0.2 2.9 3.9 0.2 0.4 0.8 0.1 5.5 1.2 10.4 0.0 1.3 0.8 0.4 7.1 2.8 0.4 3.5 3.8 1.0 3.1 0.7 3.9 8.2 11.3 2.4 5.1 6.1 1.0 5.5 0.6 0.0 0.0 7.2 0.0 2.8 1.9 4.3 1.9 2.7 0.3 1.0 0.5 0.2 0.8 0.6 0.1 0.1 1.0 0.6 1.0 0.0 2.3 1.0 0.7 1.3 1.1 0.2 0.5 1.4 0.3 5.8 9.2 20.1 16.5 5.7 7.1 5.9 5.9 12.8 1.8 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.2;intestine: 16.9;lymphoid tissue: 39.2" "Cell line enhanced" "Detected in some" "Daudi: 20.5;HDLM-2: 20.3;Karpas-707: 21.1;REH: 11.2;RPMI-8226: 12.7;U-266/70: 16.6;U-266/84: 16.3;U-698: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007419, CAB007754" Enhanced Uncertain "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favourable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favourable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 1.6 0.9 1.2 31.4 2.3 6.3 1.1 1.0 1.2 1.0 3.1 1.7 0.1 2.1 0.9 1.4 2.6 1.2 2.9 0.9 1.1 1.4 2.2 1.6 3.9 23.0 2.3 0.7 0.8 1.2 0.2 1.2 1.4 2.1 1.6 1.9 2.0 4.4 0.8 0.5 1.2 16.9 0.7 3.4 34.4 2.3 0.9 1.3 19.1 1.9 1.4 39.2 3.1 1.3 16.2 15.9 1.3 6.2 3.7 14.6 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.3 0.0 0.0 0.0 0.0 0.0 20.3 0.1 4.3 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 21.1 0.0 0.1 4.9 5.1 0.6 0.0 11.2 0.0 12.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 4.6 0.0 0.0 0.1 0.0 0.0 16.6 16.3 25.8 0.0 5.8 0.0 1.3 3.2 1.2 13.4 6.2 12.4 16.2 11.2 14.0 15.9 10.7 6.2 8.7 0.3 3.7 3.4 14.0 14.6 7.3 1.2 2.3 1.0 1.2 1.1 1.4 2.3 0.7 2.1 1.3 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784914-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavourable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 6.9 6.2 9.4 15.2 10.0 19.1 5.8 12.1 15.6 5.2 5.8 10.1 6.9 4.9 6.2 4.0 4.3 4.4 6.3 5.5 9.4 9.2 6.2 3.1 12.0 22.3 8.3 7.3 4.2 7.2 5.2 8.0 12.3 12.5 6.1 4.7 6.7 9.0 8.9 3.4 5.0 9.9 5.6 6.7 22.6 7.1 5.5 6.6 11.5 8.7 3.9 18.8 6.1 5.1 10.8 5.0 8.2 14.8 2.3 9.6 7.1 6.1 5.5 3.6 6.6 3.3 2.0 8.6 4.6 4.3 5.6 3.9 2.4 2.9 10.7 8.6 5.2 1.8 4.4 4.5 3.3 13.9 2.1 18.8 7.7 5.1 4.0 9.9 7.1 2.0 2.3 4.3 2.8 13.6 1.6 1.0 1.7 7.6 5.8 9.9 2.4 7.5 12.2 0.4 12.3 3.1 3.1 4.4 6.3 4.0 5.2 4.1 10.5 15.2 10.5 4.7 10.5 4.3 1.9 1.2 2.4 11.6 4.1 15.0 3.4 2.2 4.2 5.6 5.2 12.2 5.3 10.8 7.0 4.7 4.4 7.6 8.6 6.3 8.2 2.3 14.8 5.0 9.6 7.1 9.4 10.0 12.1 15.6 9.4 9.2 8.3 7.3 12.5 6.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437312 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 40.8;RT4: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 19.7 18.9 17.6 15.4 17.6 9.6 17.8 37.1 19.6 19.2 16.9 14.6 9.8 13.7 23.5 14.8 11.1 15.3 18.7 19.5 15.4 12.5 26.2 15.4 15.6 5.8 15.4 13.4 24.6 14.0 25.7 24.6 30.8 14.4 18.6 14.1 17.9 13.3 15.7 33.0 17.8 17.2 18.6 15.3 11.5 26.1 21.0 16.5 9.4 25.9 11.3 7.5 18.8 32.6 0.7 0.5 2.5 1.9 1.0 1.3 0.4 9.7 6.1 40.8 6.4 6.6 13.4 11.2 8.7 11.1 8.6 7.4 5.1 4.9 2.1 9.8 5.9 5.3 15.3 7.7 13.2 2.4 6.3 3.5 4.3 11.9 17.3 1.5 5.8 11.9 7.7 11.2 12.1 7.4 4.5 4.0 11.5 5.3 3.4 2.3 12.3 9.3 3.7 13.3 1.6 11.4 37.8 7.3 8.3 5.1 8.2 22.6 5.5 2.2 6.0 6.7 8.0 6.0 4.7 6.1 3.4 0.7 8.3 2.5 7.8 2.5 0.7 0.0 1.2 1.1 0.1 0.1 1.2 0.9 0.1 0.7 1.1 1.3 0.0 1.0 1.9 0.5 0.6 0.4 17.6 17.6 37.1 19.6 15.4 12.5 15.4 13.4 14.4 16.5 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavourable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 18.8 14.3 30.7 14.6 29.1 52.3 38.6 24.0 19.8 21.5 17.8 23.7 25.1 27.5 20.9 35.9 7.8 9.7 21.1 21.5 36.8 6.6 20.6 10.8 61.8 24.6 9.8 0.9 46.9 9.7 53.0 23.7 55.8 13.3 0.0 56.4 10.3 22.7 6.1 15.6 22.8 27.5 21.0 0.1 14.3 6.6 12.0 20.0 16.5 0.0 17.9 3.9 17.8 70.1 42.7 18.3 12.3 28.5 0.0 0.0 16.7 27.5 12.5 31.2 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" 14 50418501-50561126 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 26.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036696 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA036696: AB_10672362" "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-3)" "unprognostic (4.13e-2)" "unprognostic (6.31e-2)" "unprognostic (2.24e-2)" "unprognostic (1.53e-3)" "unprognostic (7.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (2.02e-2)" 17.4 11.8 23.4 12.1 44.4 16.5 19.7 24.6 32.3 25.8 17.1 43.5 13.4 11.3 29.9 12.1 18.7 17.4 19.3 10.3 24.4 14.0 10.9 8.7 15.2 9.9 48.8 17.1 29.9 13.3 16.7 17.5 17.3 26.0 16.6 15.1 9.1 16.9 19.9 10.7 24.8 12.7 22.3 30.7 13.0 14.4 6.8 51.1 8.4 15.3 8.7 11.2 19.3 21.2 5.0 2.7 26.1 1.8 5.4 3.9 1.0 23.1 7.0 17.1 14.7 15.9 16.7 16.8 27.3 24.7 18.6 16.6 8.8 16.3 16.0 16.3 25.0 16.6 15.9 14.7 28.5 13.2 11.6 9.8 12.3 7.9 13.5 8.7 15.5 12.1 12.1 16.4 17.2 24.4 9.2 10.5 27.3 8.7 11.8 8.4 8.3 13.8 14.3 26.1 6.0 18.4 18.1 5.5 12.6 15.4 10.8 10.6 12.0 6.7 24.8 24.3 17.0 16.5 12.8 7.7 7.8 10.7 9.1 6.1 17.3 26.1 1.5 13.5 3.9 1.8 2.2 3.2 2.4 3.3 1.6 5.0 2.6 2.7 0.6 5.4 1.1 2.7 0.5 1.0 23.4 44.4 24.6 32.3 24.4 14.0 48.8 17.1 26.0 51.1 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21754500-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.3" "Cell line enhanced" "Detected in all" "K-562: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069" Approved 250000 "CAB004229: AB_627547, HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 16.1 21.1 32.9 18.3 80.3 20.2 13.6 31.0 54.5 18.6 18.5 23.2 9.6 13.7 17.4 10.6 25.7 16.9 14.9 22.8 32.4 23.4 21.7 16.4 19.9 16.6 18.4 23.6 16.0 19.8 27.4 10.9 17.2 27.6 16.4 19.9 14.2 15.8 17.8 28.2 17.5 15.1 22.8 20.4 19.8 17.2 24.2 21.5 19.5 23.0 11.1 21.4 17.7 15.3 2.5 3.2 13.5 4.9 7.0 13.7 2.5 19.3 12.2 15.7 9.0 18.7 18.9 6.0 21.4 20.0 19.2 18.6 9.7 10.3 10.7 10.6 28.6 18.4 18.5 17.1 25.1 43.1 17.3 19.4 11.5 11.4 15.4 27.3 20.1 14.0 13.7 23.2 21.5 26.2 79.5 12.2 23.4 7.9 17.6 6.0 5.9 12.1 19.4 39.0 2.9 11.0 15.9 12.9 7.1 23.1 14.0 12.5 10.5 9.2 22.9 16.1 21.0 18.4 13.6 11.7 14.3 16.7 15.2 13.3 17.4 1.0 4.0 5.8 13.7 4.6 3.9 2.0 2.9 4.9 3.2 2.5 2.8 5.1 13.5 7.0 4.9 3.2 2.7 2.5 32.9 80.3 31.0 54.5 32.4 23.4 18.4 23.6 27.6 21.5 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.3" "Cell line enriched" "Detected in many" 6 "AF22: 58.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favourable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favourable (5.57e-4)" 17.2 11.9 31.6 3.7 34.5 9.7 6.2 26.1 58.3 11.4 4.0 12.6 8.1 3.2 11.0 14.2 7.4 11.9 10.4 5.1 36.0 28.6 15.0 2.7 6.5 3.9 31.5 36.4 11.3 5.6 10.9 31.5 3.4 37.9 16.6 4.3 5.4 3.4 18.9 2.0 3.5 3.9 11.4 23.1 5.3 4.3 18.2 15.8 0.0 15.3 0.4 3.6 11.1 10.2 3.7 3.0 6.9 1.8 3.3 3.6 2.3 1.0 1.9 58.9 1.8 1.6 1.3 2.2 1.2 1.1 1.0 0.4 1.1 1.7 2.6 2.0 0.7 3.6 0.6 1.5 1.7 3.7 1.6 2.1 2.3 1.9 1.4 0.9 1.2 1.6 0.7 1.4 1.9 1.2 1.9 9.7 0.6 1.5 1.7 1.1 3.4 1.2 1.8 1.5 0.9 4.2 6.2 3.6 3.2 1.2 4.8 0.8 3.5 1.2 2.7 2.6 2.6 1.1 1.0 3.2 1.9 1.6 3.7 1.3 1.4 6.9 1.8 3.3 2.3 1.6 2.4 3.7 1.9 2.5 1.6 3.3 2.7 3.6 6.2 3.3 1.5 3.0 2.7 2.3 31.6 34.5 26.1 58.3 36.0 28.6 31.5 36.4 37.9 15.8 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria Mitochondria "CAB012961: AB_2533144, HPA045069: " "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavourable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 20.4 5.7 14.2 7.5 17.3 0.8 8.2 22.0 23.7 6.6 2.7 2.8 1.0 1.9 8.2 6.2 5.3 7.0 8.8 8.8 11.7 9.1 5.0 1.5 8.5 8.5 7.2 19.9 5.3 3.1 6.4 10.9 8.4 6.6 7.2 2.7 4.1 5.7 8.0 5.0 6.4 2.6 9.8 5.5 7.3 4.6 3.1 4.1 0.9 4.5 5.3 6.1 6.0 4.4 1.1 0.0 0.0 0.3 0.0 0.9 0.0 1.7 4.2 4.6 17.3 6.1 9.2 0.1 6.4 4.6 4.3 1.7 1.6 3.2 0.0 5.8 6.0 4.2 3.0 2.6 0.3 8.9 2.1 6.1 5.5 0.4 7.0 1.5 9.5 12.8 7.6 1.2 0.5 9.4 4.9 16.7 4.2 7.4 0.3 5.6 0.4 4.8 16.7 0.1 5.9 6.5 0.0 4.3 11.5 5.5 2.3 4.6 7.6 4.8 14.7 12.9 10.8 0.9 2.4 0.7 1.9 7.1 6.5 1.7 10.8 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.4 0.2 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 14.2 17.3 22.0 23.7 11.7 9.1 7.2 19.9 6.6 4.1 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261825 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 104.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31 "NK-cell: 3.0" "Lineage enriched" "Detected in single" 31 "NK-cells: 3.0" "Region enhanced" "Detected in many" "cerebellum: 35.4" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: " "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 3.0 1.6 4.5 2.1 4.5 1.0 1.8 9.0 7.0 2.1 1.4 2.1 1.6 2.0 5.4 5.1 3.3 2.9 2.4 5.1 3.9 3.6 2.5 1.0 2.1 2.0 3.5 5.7 3.0 1.4 1.2 7.0 2.3 2.6 2.9 1.1 2.2 1.4 3.7 104.2 0.9 1.5 4.2 2.6 1.6 1.5 1.6 2.4 0.0 1.3 10.8 1.1 2.4 1.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 10.3 6.4 2.4 7.4 5.6 6.2 3.5 7.9 6.9 13.3 8.5 9.2 3.2 19.4 10.8 8.7 6.9 11.0 1.6 2.5 5.6 15.4 12.7 19.3 11.4 17.9 11.9 25.2 13.4 2.9 3.0 0.0 15.0 11.2 18.1 6.1 5.7 0.0 15.9 7.5 10.4 18.1 6.7 19.7 7.9 1.4 8.5 2.9 6.1 0.2 9.8 3.3 13.8 7.8 13.7 12.4 2.9 4.9 4.2 3.2 10.4 3.5 11.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 4.5 4.5 9.0 7.0 3.9 3.6 3.5 5.7 2.6 2.4 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 45.7;RPMI-8226: 27.6;RT4: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 16.5;T-cells: 27.8" "Region enhanced" "Detected in some" "cerebellum: 6.5" "Region enriched" "Detected in some" 15 "cerebellum: 59.9" "HPA007667, CAB025854" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favourable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 6.5 22.0 2.2 5.4 4.0 2.9 6.8 2.8 7.3 6.8 18.9 0.5 36.8 18.8 1.9 10.3 41.1 2.4 12.0 1.2 1.7 1.8 6.5 2.8 9.6 11.2 0.8 3.8 3.9 24.6 18.8 12.4 10.5 2.5 6.8 16.0 2.4 20.7 26.3 0.9 28.6 37.7 2.1 0.8 5.9 12.2 23.7 1.1 5.0 13.8 16.0 18.5 7.3 13.9 16.5 0.1 5.2 0.3 2.8 27.8 6.7 19.3 0.1 0.3 0.2 1.1 5.6 2.7 1.5 0.2 0.2 0.5 16.2 19.1 4.6 1.2 1.5 15.1 0.0 45.7 0.4 11.8 5.1 0.1 0.5 16.0 1.9 0.1 1.2 4.8 16.2 2.9 0.6 3.0 0.3 5.2 0.5 10.2 0.1 1.2 0.1 0.3 11.4 0.2 27.6 8.8 28.6 19.3 0.3 1.7 0.3 0.1 21.7 2.5 4.0 1.4 0.2 0.5 0.3 0.3 6.9 1.4 0.0 0.5 0.1 5.2 0.3 4.5 16.2 0.0 10.5 10.8 11.6 13.0 0.1 16.5 10.6 11.9 3.9 2.8 0.0 0.0 27.8 6.7 2.2 4.0 2.8 7.3 1.7 1.8 0.8 3.8 2.5 1.1 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 32.1;neutrophil: 12.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" 7100000 "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 21.5 20.6 11.7 18.4 15.5 49.9 20.7 26.5 18.1 22.0 20.5 12.5 11.9 16.9 38.8 12.1 24.0 18.9 16.0 16.4 9.3 9.5 16.0 29.8 21.5 29.0 12.0 11.3 17.7 18.5 15.0 27.2 27.3 10.2 23.4 18.3 17.0 16.7 16.5 21.2 25.6 22.5 26.0 10.6 35.5 18.2 11.1 10.3 34.1 20.9 17.6 20.8 25.0 30.0 2.3 4.0 32.1 4.9 3.0 2.8 2.1 18.3 10.1 10.9 17.5 24.8 24.8 24.0 19.2 25.0 22.8 23.8 24.7 9.5 14.9 19.1 21.1 13.2 18.0 16.6 23.9 16.8 14.3 34.4 14.4 20.6 13.7 21.6 20.8 17.4 16.2 16.4 16.3 25.8 19.0 18.7 15.5 8.7 22.2 26.0 6.7 10.1 26.4 17.7 13.8 16.1 25.3 8.2 7.0 17.3 13.0 20.1 15.3 40.4 18.1 20.5 11.9 12.9 17.6 9.2 21.0 14.9 9.3 42.8 16.8 32.1 4.9 3.0 2.4 3.5 2.8 1.5 2.2 2.6 4.0 2.3 2.5 2.4 12.3 3.0 4.7 1.9 2.6 2.1 11.7 15.5 26.5 18.1 9.3 9.5 12.0 11.3 10.2 10.3 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716259-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9;epididymis: 27.6;fallopian tube: 29.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.1;HeLa: 14.0;MCF7: 13.6;T-47d: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 0.6 0.1 3.6 0.3 8.1 0.1 1.1 0.2 2.1 4.5 0.4 8.7 5.2 0.5 2.2 27.6 1.3 29.5 0.4 1.1 5.4 4.6 3.9 0.2 7.4 0.5 0.2 1.5 4.7 2.0 9.1 4.2 0.6 26.9 0.9 0.4 1.6 3.0 2.4 0.2 4.9 0.7 0.5 0.4 0.5 0.9 7.3 2.4 0.1 8.4 0.5 0.4 0.5 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.7 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 7.1 0.0 1.3 0.0 5.3 0.0 0.2 0.0 1.1 1.6 0.0 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 13.6 0.0 0.0 2.0 1.1 0.0 2.9 0.3 0.9 1.3 3.9 3.9 0.0 2.8 0.0 12.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 8.1 0.2 2.1 5.4 4.6 0.2 1.5 26.9 2.4 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 25.1;neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Approved Nucleoplasm Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavourable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 24.9 18.5 63.3 15.3 43.2 15.6 21.1 24.8 52.0 21.3 45.1 30.4 6.3 39.7 24.2 11.4 44.1 28.7 25.6 21.2 37.1 34.0 13.4 8.8 23.3 13.1 33.8 27.4 32.7 13.0 26.1 15.2 27.6 27.6 20.1 36.7 26.2 17.1 18.3 13.9 18.7 49.2 24.0 27.8 15.9 33.7 11.6 19.5 8.4 20.5 18.7 26.0 18.2 22.2 1.4 1.5 25.1 2.7 0.8 3.1 1.4 13.7 7.5 16.1 9.1 40.5 53.8 9.0 10.3 25.6 16.4 19.6 9.0 27.8 13.9 10.2 28.8 5.1 13.5 12.1 16.0 26.3 15.7 4.3 8.3 15.0 40.7 3.1 11.9 33.1 7.0 18.7 8.4 41.6 5.8 17.9 21.6 36.3 14.3 5.0 4.3 6.6 17.0 9.6 31.2 14.9 8.7 14.2 10.1 5.9 20.8 6.0 13.6 7.6 29.4 10.8 9.3 12.3 3.5 20.3 9.3 7.1 21.6 6.7 7.6 2.4 2.7 25.1 0.9 1.9 1.4 1.3 2.1 1.6 1.4 1.4 1.5 1.6 11.3 0.8 1.0 1.5 3.1 1.4 63.3 43.2 24.8 52.0 37.1 34.0 33.8 27.4 27.6 19.5 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560078-50731824 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.4;brain: 33.4;parathyroid gland: 43.5" "Cell line enhanced" "Detected in some" "HAP1: 3.0;HeLa: 4.4;NTERA-2: 3.0;SCLC-21H: 15.4;SH-SY5Y: 3.7" "Group enriched" "Detected in many" 5 "glioma: 15.2;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 1.9 26.4 16.9 1.1 33.4 0.9 1.8 15.9 23.9 1.4 2.6 9.5 3.8 1.6 1.8 4.5 3.5 1.5 3.0 16.9 13.0 14.3 4.5 7.0 3.5 0.9 17.1 9.1 4.2 2.5 43.5 8.3 3.7 20.5 5.3 1.8 4.1 1.8 12.4 1.7 1.0 1.9 5.2 11.8 1.1 1.3 3.5 12.4 1.7 7.8 0.0 0.9 2.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.5 1.4 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.1 15.4 3.7 0.0 1.1 2.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 33.4 15.9 14.5 13.0 14.3 17.1 9.1 20.5 12.4 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067372 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262" Approved Supported Enhanced Cytosol Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868" "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 11.8 7.4 14.4 10.9 23.2 25.6 13.7 33.0 24.5 16.3 18.7 12.5 9.3 16.3 15.9 13.3 32.3 8.2 17.0 9.1 13.3 15.9 14.4 32.6 12.6 9.4 13.1 16.8 11.5 8.5 12.2 15.3 13.9 23.8 10.5 18.1 9.5 17.9 11.4 27.1 24.0 26.2 17.8 14.2 9.2 15.7 25.7 13.0 11.7 13.4 22.7 12.4 18.9 22.4 4.9 4.2 3.0 4.5 6.5 7.9 3.6 8.7 11.8 23.3 8.9 7.2 11.9 17.0 12.5 12.6 11.6 13.7 14.1 5.3 12.6 8.8 16.0 12.4 17.9 23.9 15.9 7.7 5.6 18.8 7.0 22.3 17.4 14.0 40.2 12.7 43.9 14.0 36.4 10.9 24.3 21.5 14.7 19.7 9.8 11.0 8.2 5.7 8.6 15.0 20.2 11.1 36.9 11.4 10.8 10.1 8.2 18.3 7.5 20.9 10.8 13.9 15.0 9.0 16.7 11.2 32.9 15.6 17.2 20.6 17.0 3.0 4.5 1.2 3.8 4.3 4.7 4.9 5.6 4.3 4.2 2.6 5.4 3.8 0.6 6.5 2.8 1.9 7.9 3.6 14.4 23.2 33.0 24.3 13.3 15.9 13.1 16.8 23.8 13.0 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: " "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.5 15.0 6.4 7.3 7.6 9.2 11.8 12.5 7.9 13.4 15.3 7.2 6.0 9.2 13.1 14.1 17.3 9.4 11.8 8.2 5.9 4.7 10.8 4.8 9.9 9.2 8.2 5.2 25.4 5.7 7.3 7.5 12.5 6.7 14.0 6.9 10.5 7.8 12.3 7.5 13.1 11.2 13.8 7.1 13.2 8.0 13.3 7.5 4.5 8.6 11.3 10.6 12.7 15.9 2.2 2.6 11.5 7.4 5.5 4.7 3.0 4.1 6.5 5.4 4.2 27.1 11.3 6.3 5.6 5.2 7.8 7.2 7.5 0.7 2.5 4.6 9.7 4.6 6.3 5.1 4.9 4.3 4.8 1.2 4.7 3.3 11.7 1.1 4.2 11.9 3.6 11.8 4.2 5.7 2.2 0.9 7.7 2.7 8.3 4.4 6.2 4.3 4.5 7.9 1.7 2.6 2.3 2.4 7.2 5.7 0.5 2.9 3.5 1.4 3.2 8.4 6.2 9.2 3.8 1.6 2.4 0.6 9.7 1.0 5.0 1.0 3.6 11.5 4.7 7.4 2.5 2.2 2.2 4.1 2.6 1.4 2.1 2.6 1.3 5.5 6.5 1.7 1.0 3.0 6.4 7.6 12.5 7.9 5.9 4.7 8.2 5.2 6.7 7.5 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favourable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 13.4 11.7 15.3 11.5 18.5 13.3 22.1 33.6 35.2 15.2 13.9 12.9 19.5 16.7 17.1 10.8 16.1 12.4 15.1 11.2 20.0 18.0 20.1 23.6 11.7 12.0 15.9 16.7 18.9 15.3 12.7 23.7 12.2 23.6 13.0 14.3 12.4 17.2 15.9 18.9 10.8 17.7 14.6 13.7 9.6 12.2 23.4 12.2 20.5 22.3 9.0 13.8 11.8 13.0 4.5 4.3 5.2 4.3 4.7 5.7 3.5 15.7 4.3 14.3 8.1 5.5 6.5 11.1 23.8 16.3 14.3 11.7 4.9 16.4 5.7 6.5 13.3 9.7 5.0 9.2 18.7 34.1 8.2 8.2 5.0 6.7 9.1 14.0 9.6 5.5 10.6 10.6 21.1 13.1 13.1 10.6 9.3 4.6 17.1 7.4 8.9 3.1 11.2 14.7 5.7 8.7 6.1 24.1 19.1 9.3 7.8 10.7 8.5 6.7 11.2 10.7 25.6 8.1 17.9 3.3 8.1 11.6 7.4 14.9 6.1 0.0 3.3 3.0 4.1 2.8 4.7 4.5 5.7 5.0 3.3 2.9 5.6 3.9 5.2 4.7 4.3 4.3 2.9 3.5 15.3 18.5 33.6 35.2 20.0 18.0 15.9 16.7 23.6 12.2 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell line enhanced" "Detected in all" "HDLM-2: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "basophil: 13.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008910 Approved "CAB008910: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favourable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 10.3 12.4 22.9 9.6 31.8 10.3 11.4 48.7 41.4 10.8 12.4 10.6 4.7 10.1 8.7 9.5 8.7 8.8 7.8 14.0 24.3 25.0 12.2 9.7 10.8 10.0 22.0 21.0 8.5 25.9 16.3 8.8 10.9 29.4 11.7 15.3 7.0 9.9 13.1 20.5 6.3 10.4 11.4 16.8 8.6 12.3 9.4 10.3 7.1 15.4 5.1 11.3 9.9 7.3 1.4 1.4 13.2 2.4 1.3 3.1 0.3 17.0 14.1 12.5 15.6 12.4 13.9 26.9 16.4 14.6 13.9 13.9 18.5 12.2 18.3 28.4 17.4 13.1 12.8 27.6 16.3 68.7 12.4 7.6 15.7 13.1 9.4 15.7 13.3 10.2 12.4 13.4 13.0 16.4 8.4 13.3 18.8 22.4 15.6 6.6 8.7 8.4 15.2 21.3 8.7 10.5 16.4 14.4 10.2 19.3 18.8 13.1 19.1 13.7 11.7 16.6 16.8 23.4 24.5 9.6 11.3 12.5 17.6 14.7 11.0 13.2 0.6 2.5 2.0 1.3 2.0 1.0 1.5 1.8 1.0 1.4 1.0 1.2 0.9 1.3 2.4 1.4 3.1 0.3 22.9 31.8 48.7 41.4 24.3 25.0 22.0 21.0 29.4 10.3 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: , HPA063708: , HPA064435: " "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 20.9 8.3 11.5 12.9 34.0 20.0 14.3 14.6 33.1 22.3 21.1 15.8 10.2 10.1 10.2 29.4 15.9 8.6 15.5 16.1 11.7 6.5 16.9 10.3 10.2 26.3 24.9 56.6 27.5 19.9 21.4 23.7 18.2 19.4 45.9 18.0 26.0 10.0 18.0 13.3 11.6 25.8 24.1 3.2 16.8 12.8 9.2 11.9 17.2 29.1 20.2 14.1 24.2 17.3 20.1 17.0 23.3 19.8 59.8 53.1 8.2 22.8 15.2 6.6 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm Nucleoplasm "HPA058275: " "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favourable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favourable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.0 7.1 3.0 8.5 4.6 11.5 6.7 5.6 8.0 8.7 7.4 11.1 21.5 9.3 5.7 18.7 8.2 20.5 22.1 7.8 20.4 4.9 48.7 10.2 10.1 9.1 35.0 25.9 9.1 13.8 20.2 27.5 7.6 13.6 6.1 18.2 9.4 14.9 35.3 11.2 29.5 6.6 7.2 13.9 40.3 13.2 5.6 4.0 5.0 14.2 6.4 8.9 21.7 5.5 6.8 15.7 35.3 13.8 4.1 7.6 7.7 36.4 55.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavourable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 15.1 20.2 19.5 16.4 14.1 14.3 29.7 15.2 18.4 23.4 16.2 26.0 12.5 22.9 11.3 17.9 15.2 25.6 15.9 22.0 15.2 14.0 20.4 14.0 20.8 17.1 25.6 14.5 15.1 22.9 22.3 26.6 17.1 28.1 9.1 17.0 17.0 25.4 40.5 27.7 14.2 25.2 14.2 22.0 18.6 22.0 24.1 20.4 17.3 29.5 21.1 23.8 29.3 14.9 13.3 13.4 13.6 19.0 18.6 22.7 27.1 16.2 18.7 18.8 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 MARCH1 "FLJ20668, MARCH-I, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4;lymphoid tissue: 32.4" "Cell line enhanced" "Detected in many" "Daudi: 9.4;U-266/70: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 95 "classical monocyte: 16.8;eosinophil: 9.9;intermediate monocyte: 17.0;memory B-cell: 18.5;myeloid DC: 18.1;naive B-cell: 15.7;non-classical monocyte: 17.2;plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014600 Uncertain Supported Mitochondria Mitochondria "HPA014600: AB_1853573" "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 7.7 4.2 11.6 20.5 19.7 3.9 4.0 3.1 14.5 3.7 3.9 8.5 0.1 4.4 3.9 4.6 3.6 4.2 5.9 2.6 12.6 10.1 3.0 4.5 8.3 28.5 17.3 6.3 4.2 4.1 1.5 4.1 10.2 13.5 3.5 5.1 2.4 4.6 1.8 1.6 4.9 9.0 6.5 24.4 32.4 4.1 2.3 17.9 2.6 3.2 1.4 24.6 9.0 4.2 18.5 18.1 9.9 17.2 0.1 0.0 6.6 0.8 0.7 2.9 1.7 0.0 0.0 1.8 1.2 0.1 0.0 0.0 1.6 3.3 9.4 3.5 0.0 1.4 0.0 0.0 0.0 1.0 1.0 6.7 3.7 0.6 0.0 4.1 2.2 0.0 0.0 0.0 0.2 0.0 2.5 4.9 3.3 1.0 2.3 2.6 3.6 1.3 2.6 0.5 0.7 0.1 1.5 1.5 1.3 0.9 1.4 0.5 4.0 0.7 3.1 1.1 2.0 0.7 2.3 9.7 3.2 2.6 1.3 2.1 1.5 0.0 16.8 9.9 0.0 17.0 0.0 18.5 0.0 0.0 18.1 15.7 0.0 0.0 0.1 0.1 17.2 6.8 0.0 6.6 11.6 19.7 3.1 12.5 12.6 10.1 17.3 6.3 13.5 17.9 MARCH10 "FLJ35757, MARCH-X, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 80.2" "Cell line enhanced" "Detected in some" "BEWO: 3.8;EFO-21: 7.2;HSkMC: 3.2;SCLC-21H: 12.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.2 0.1 0.7 0.2 1.6 0.0 0.1 0.1 0.3 0.5 0.1 1.9 0.6 0.0 0.3 4.8 0.1 7.9 0.1 0.1 1.0 1.0 0.6 0.1 1.4 0.1 0.2 0.5 1.0 0.1 0.3 4.5 0.1 1.8 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 80.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.0 0.6 3.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 3.8 1.6 0.2 1.2 0.3 0.0 0.1 0.0 7.2 0.5 0.0 0.0 0.4 1.3 0.0 0.0 1.2 0.7 0.0 1.5 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.4 0.1 0.1 0.3 0.2 0.0 0.0 0.2 1.1 0.0 12.4 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.7 0.3 0.7 0.1 0.6 1.8 0.0 0.6 0.0 0.0 0.7 0.3 0.7 1.6 0.1 0.3 1.0 1.0 0.2 0.5 1.8 0.3 MARCH11 "MARCH-XI, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 42.1" "Cell line enriched" "Detected in some" 14 "SH-SY5Y: 43.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (9.91e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" 0.4 1.1 1.8 0.3 3.4 0.3 0.4 3.7 3.7 0.3 0.4 0.0 0.0 0.3 0.4 0.3 0.3 0.3 0.3 2.2 2.0 3.2 0.5 0.5 0.4 0.3 1.5 2.0 0.5 1.0 0.3 6.8 0.4 2.1 0.6 0.4 0.6 1.4 0.3 0.3 0.3 0.4 0.3 0.5 0.3 0.4 42.1 0.0 0.0 0.3 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.4 3.7 3.7 2.0 3.2 1.5 2.0 2.1 0.0 MARCH2 "HSPC240, MARCH-II, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavourable (6.48e-4)" "prognostic favourable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favourable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favourable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 37.7 12.4 30.7 13.5 28.3 17.5 23.9 8.6 39.1 9.8 29.8 20.7 9.7 11.2 12.5 39.0 19.3 10.0 11.4 38.9 23.5 21.9 11.0 17.9 18.2 15.0 30.8 19.8 8.2 10.0 10.5 11.3 13.9 20.2 16.0 10.3 12.7 13.4 21.8 46.9 12.7 11.7 28.5 27.8 18.9 13.3 8.6 13.3 8.4 21.3 14.1 10.0 20.4 9.7 3.6 26.5 20.4 14.6 3.7 7.3 10.1 5.4 7.0 3.2 14.7 19.5 6.4 5.4 6.0 7.3 4.8 5.0 3.4 2.6 2.2 17.6 12.8 3.9 4.1 8.4 3.7 10.9 9.7 16.7 3.3 7.6 10.5 2.4 25.1 7.6 9.7 4.6 4.1 18.7 2.3 12.3 3.7 10.5 3.3 7.9 6.6 17.0 5.3 1.0 5.5 11.0 6.5 1.6 8.9 0.4 6.4 11.3 4.9 5.2 18.8 6.7 4.1 22.3 5.0 11.0 13.0 2.5 10.9 5.0 5.1 20.4 10.0 15.4 5.7 14.6 5.9 3.6 5.9 4.6 6.7 3.5 4.0 5.4 12.5 3.7 12.8 26.5 7.3 10.1 30.7 28.3 8.6 39.1 23.5 21.9 30.8 19.8 20.2 13.3 MARCH3 "MARCH-III, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030808 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 24.6;HUVEC TERT2: 16.4;TIME: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 8.8;naive B-cell: 13.1" "Lineage enriched" "Detected in many" 5 "B-cells: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043406 Uncertain Supported Vesicles Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 11.3 6.0 5.6 11.0 9.4 6.6 6.2 5.3 4.8 2.0 10.8 8.2 0.5 2.4 3.7 3.6 3.4 3.2 10.4 15.2 7.8 6.8 2.0 1.9 5.2 5.2 9.5 2.3 4.0 5.0 1.7 10.8 4.0 12.3 2.9 11.8 9.7 11.2 1.1 11.9 11.5 5.2 6.5 16.0 3.7 5.5 14.2 7.6 2.1 3.6 3.4 5.8 6.5 6.7 13.1 0.7 2.5 0.4 1.9 2.6 0.7 0.3 1.2 2.3 1.2 2.1 2.0 0.7 8.4 3.5 6.8 10.0 1.1 0.5 2.2 0.8 1.3 0.7 2.9 1.5 9.6 0.5 2.7 7.0 1.9 1.1 3.4 2.8 1.8 1.4 0.5 24.6 2.9 16.4 2.9 0.4 5.5 0.8 0.3 1.2 2.0 2.8 0.9 9.4 0.6 0.5 1.2 0.7 0.5 1.9 0.3 1.0 1.7 2.9 19.9 1.3 1.0 7.7 0.9 1.1 1.3 1.3 5.0 2.3 1.1 0.0 0.2 2.5 0.5 0.4 0.1 8.8 0.6 0.3 0.1 13.1 2.4 0.5 0.8 1.9 0.3 0.7 2.6 0.7 5.6 9.4 5.3 4.8 7.8 6.8 9.5 2.3 12.3 7.6 MARCH4 "KIAA1399, MARCH-IV, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372027 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 16.6;pituitary gland: 13.1" "Cell line enhanced" "Detected in many" "BJ: 33.3;fHDF/TERT166: 21.2;TIME: 15.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014348 Approved "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.7 2.9 7.0 0.7 11.9 0.7 0.6 1.0 16.6 0.6 1.1 0.3 0.0 1.5 0.7 0.7 0.6 2.5 0.6 0.6 5.8 5.6 0.6 0.6 0.8 0.6 2.0 4.8 0.6 1.5 0.6 13.1 3.1 3.4 0.7 1.2 0.1 0.6 0.6 0.6 0.7 1.4 0.6 1.6 0.6 5.1 0.7 1.1 0.0 0.6 0.0 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.5 1.2 0.0 0.0 0.1 0.8 0.0 33.3 11.4 7.2 2.5 0.0 0.5 0.0 5.2 21.2 0.0 0.0 13.1 7.1 0.0 0.0 2.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.5 9.9 9.3 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.9 0.0 0.0 0.0 0.0 0.0 15.6 11.2 11.6 0.0 8.9 0.0 0.0 0.0 2.5 0.0 7.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.0 11.9 1.0 16.6 5.8 5.6 2.0 4.8 3.4 1.1 MARCH5 "FLJ20445, MARCH-V, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291163-92353964 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria Mitochondria "HPA056596: " "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" 18.2 21.7 17.5 17.7 18.3 20.7 27.1 16.8 25.7 15.5 15.4 12.7 20.7 15.8 19.3 18.8 28.0 14.8 15.4 18.4 15.8 15.1 21.7 27.6 16.5 16.6 16.3 17.9 20.9 16.7 16.3 12.3 16.3 14.8 22.2 14.8 14.5 19.4 19.3 42.6 13.7 16.0 18.1 14.0 12.1 14.4 20.1 13.5 25.0 24.5 21.5 17.3 14.7 21.0 7.3 9.4 16.8 10.2 6.5 8.7 6.6 16.4 8.9 17.6 20.2 12.1 12.6 9.1 14.7 16.2 18.4 18.9 5.9 11.8 9.6 10.2 14.4 13.6 12.3 12.3 26.5 7.2 14.5 7.7 8.4 13.9 14.6 12.3 7.7 12.8 16.7 12.1 25.5 16.1 8.4 12.0 14.7 10.4 10.8 14.1 4.1 13.5 11.8 18.1 5.7 18.8 10.7 8.2 15.2 12.8 9.5 15.6 16.5 9.6 15.6 8.6 9.5 9.4 20.1 12.2 9.3 8.5 7.9 17.0 5.7 5.2 8.3 9.0 7.6 10.2 7.6 7.3 8.4 8.0 9.4 6.7 8.7 8.3 16.8 6.5 8.5 6.2 7.8 6.6 17.5 18.3 16.8 25.7 15.8 15.1 16.3 17.9 14.8 13.5 MARCH6 "MARCH-VI, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353703-10440388 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA040841: , HPA063246: " "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" 22.5 25.6 28.6 21.2 25.5 57.0 62.4 42.0 53.8 21.4 23.0 24.0 18.3 28.6 24.7 24.2 22.8 25.1 22.0 35.5 27.6 23.7 31.9 28.9 35.0 33.2 29.8 39.1 34.0 41.5 56.0 27.4 20.3 33.4 21.4 18.4 20.3 28.0 23.4 49.8 23.9 32.1 27.4 38.6 31.2 26.0 25.6 26.9 18.0 26.8 17.1 20.3 24.6 36.4 13.4 7.3 15.6 12.1 9.9 15.7 9.4 12.4 18.7 31.4 24.3 18.0 14.5 25.7 19.7 18.4 17.0 21.8 17.8 33.3 13.1 30.1 18.4 17.3 16.6 12.8 23.1 27.7 15.1 17.1 62.2 12.1 12.7 20.2 19.2 16.9 14.2 17.1 18.7 15.8 20.4 29.6 15.5 14.2 10.9 15.6 11.4 13.2 17.0 13.1 18.9 13.3 24.2 13.5 19.6 36.7 20.1 12.9 16.7 11.0 15.2 20.7 20.2 10.2 14.7 20.8 29.8 18.7 15.2 14.1 14.7 15.6 8.5 13.6 13.5 9.6 15.4 13.4 13.4 13.4 7.3 11.5 15.7 14.6 13.7 9.9 12.1 5.6 11.7 9.4 28.6 25.5 42.0 53.8 27.6 23.7 29.8 39.1 33.4 26.9 MARCH7 "AXOT, MARCH-VII, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavourable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 31.6 21.1 18.3 27.4 29.0 22.6 28.9 33.1 23.0 33.4 25.3 17.0 22.0 17.1 32.3 24.1 47.6 22.7 22.4 28.1 16.9 14.4 21.8 30.9 29.5 32.9 21.6 17.8 31.6 15.4 25.3 31.5 41.3 21.5 28.8 22.3 24.8 25.7 22.6 48.0 24.2 25.2 33.8 20.4 28.9 20.0 34.1 21.8 60.4 28.5 25.5 32.9 30.0 35.1 10.0 10.1 46.1 14.5 14.0 14.6 10.5 18.5 12.8 34.5 15.5 25.0 33.1 33.4 31.2 31.6 32.1 29.5 26.4 22.3 26.4 14.2 32.5 23.5 21.2 28.8 41.2 27.0 15.6 35.8 18.6 19.9 24.3 29.3 28.0 29.4 32.9 39.2 34.0 38.5 27.2 25.5 32.4 15.2 18.7 28.1 32.5 18.4 27.9 25.5 21.9 29.5 38.7 20.5 19.3 25.5 18.8 25.0 21.8 35.6 34.7 34.4 20.8 21.1 17.6 20.4 21.4 36.0 21.3 17.8 32.0 24.8 10.3 20.6 11.1 10.6 13.3 10.0 12.1 12.6 10.1 9.7 14.6 14.1 46.1 14.0 14.5 7.9 12.5 10.5 18.3 29.0 33.1 23.0 16.9 14.4 21.6 17.8 21.5 21.8 MARCH8 "c-MIR, CMIR, MARCH-VIII, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favourable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favourable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 10.0 17.6 13.5 11.4 16.0 28.8 12.1 37.5 12.2 10.3 14.6 24.5 8.5 9.7 14.3 8.2 7.5 11.1 9.9 14.1 12.7 11.8 11.0 16.7 10.3 13.5 19.0 9.3 14.2 18.2 15.1 18.1 13.2 14.5 8.8 12.9 12.9 11.5 11.4 9.0 8.9 18.8 12.4 18.2 14.3 9.7 43.2 14.9 10.5 11.5 8.5 13.6 11.0 8.0 5.3 1.7 13.6 1.8 7.3 4.7 2.4 9.1 9.2 7.9 7.0 11.5 14.4 5.9 4.2 19.8 7.8 8.6 2.3 9.5 13.2 7.3 12.3 1.7 8.6 7.2 7.3 20.0 9.5 5.1 4.2 5.5 8.0 6.1 22.7 11.7 9.3 4.0 10.5 12.8 14.3 13.0 6.0 3.2 6.2 3.9 2.6 3.0 7.0 7.9 3.8 5.9 5.3 7.0 9.8 8.3 2.0 7.9 12.2 2.9 8.7 6.2 8.0 9.0 6.6 23.0 18.4 5.8 12.2 8.6 1.6 9.7 1.1 10.0 3.1 1.8 4.7 3.5 3.4 3.3 1.6 5.3 2.7 3.3 13.6 7.3 0.9 1.7 3.1 2.4 13.5 16.0 37.5 12.2 12.7 11.8 19.0 9.3 14.5 14.9 MARCH9 "FLJ36578, RNF179" ENSG00000139266 "Membrane associated ring-CH-type finger 9" Q86YJ5 12 57755098-57760407 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 12 "RH-30: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.96e-2)" "unprognostic (6.78e-2)" "unprognostic (1.90e-3)" "prognostic favourable (3.07e-4)" "unprognostic (2.16e-1)" "unprognostic (6.85e-2)" "unprognostic (8.15e-3)" "prognostic favourable (1.54e-5)" "unprognostic (7.76e-2)" "prognostic favourable (1.59e-4)" "unprognostic (1.08e-2)" "unprognostic (1.06e-1)" "prognostic favourable (2.98e-5)" "unprognostic (2.44e-1)" "unprognostic (2.86e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" 5.9 11.8 11.0 10.7 14.1 6.1 8.8 25.0 16.6 9.5 9.3 7.8 17.5 10.1 6.8 11.9 8.3 9.6 14.3 12.2 10.8 9.9 16.9 5.6 16.5 16.6 7.7 11.0 6.4 14.4 26.3 24.6 10.3 7.4 11.0 9.0 16.8 12.3 17.6 10.5 13.4 12.7 7.0 6.1 19.4 11.6 5.2 6.8 37.6 20.2 6.2 17.8 9.2 7.7 6.8 11.0 2.2 0.7 3.0 6.1 1.3 3.0 1.5 2.4 2.6 0.2 0.0 3.1 0.4 3.2 1.8 1.8 1.9 2.4 7.5 2.5 0.0 2.7 3.9 3.3 1.2 4.4 4.3 0.9 1.1 1.0 2.3 0.9 1.5 0.3 3.5 0.5 1.9 0.8 1.3 7.7 0.4 2.8 4.7 1.1 1.5 3.3 3.9 107.7 8.0 3.6 2.7 5.4 3.6 0.2 0.2 2.0 5.4 1.8 0.0 2.4 1.9 1.3 1.5 8.7 3.9 4.5 2.6 0.2 2.4 2.2 0.5 0.1 4.0 0.7 5.9 5.3 6.0 5.2 1.5 6.8 6.1 4.6 0.2 3.0 0.2 11.0 3.6 1.3 11.0 14.1 25.0 16.6 10.8 9.9 7.7 11.0 7.4 6.8 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 9.4;RT4: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favourable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.8 1.5 2.2 1.5 2.3 0.0 0.0 0.0 0.0 0.0 2.3 9.4 6.1 1.1 0.0 6.9 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.7 2.2 0.0 7.0 0.0 0.0 35.3 6.5 5.8 0.3 0.3 0.4 0.7 0.0 0.0 0.0 3.5 4.8 6.1 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: " "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.4 15.0 12.3 12.9 6.7 8.9 17.1 9.1 8.8 13.2 10.2 16.1 23.7 16.6 16.2 9.5 29.0 11.8 14.3 11.5 11.4 9.3 18.2 11.8 10.4 7.6 19.8 24.1 4.9 19.5 12.1 10.5 10.8 15.5 19.1 8.7 27.6 20.7 14.1 14.0 10.9 17.1 9.1 18.3 9.8 18.6 17.0 11.4 15.8 40.4 10.6 29.4 11.8 10.3 14.0 8.8 18.0 10.1 11.6 12.0 16.2 9.5 10.4 11.1 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.2 16.1 23.5 17.7 28.2 22.1 20.3 23.6 24.9 28.6 27.5 12.6 20.9 15.8 15.0 22.1 25.0 25.6 25.4 36.4 18.4 11.3 20.4 17.1 15.8 53.2 23.3 13.6 25.6 23.6 23.1 47.4 26.4 21.0 37.0 21.4 35.6 15.9 20.7 17.2 24.3 20.9 24.0 12.7 25.3 28.3 20.7 20.6 25.0 17.2 22.9 23.4 20.0 22.8 15.4 10.9 28.6 21.0 24.0 30.4 19.0 18.7 18.7 20.7 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavourable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.8 3.8 15.0 10.9 10.7 17.1 4.2 6.6 10.3 9.8 9.2 2.3 5.1 4.3 5.6 12.0 6.0 10.6 9.6 5.5 7.8 8.7 8.5 4.6 8.2 19.7 2.1 7.4 21.2 13.7 8.2 9.5 13.1 10.8 10.7 10.6 7.4 7.5 6.7 6.4 3.3 29.3 4.9 2.8 9.3 7.2 28.1 12.4 9.7 8.6 5.0 4.1 12.4 10.6 8.8 6.7 6.0 4.2 12.0 9.5 4.8 9.4 4.0 7.0 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874951 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8;SCLC-21H: 26.2;SH-SY5Y: 13.0;U-266/70: 10.7" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "MAIT T-cell: 3.6;T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Approved Vesicles Vesicles "HPA028181: AB_10603872, HPA073106: " "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 1.2 5.2 20.4 1.7 13.6 1.6 1.5 51.0 40.1 1.1 1.5 1.4 0.0 1.7 1.3 1.2 1.3 1.2 1.6 1.3 16.1 16.3 1.2 1.3 1.2 1.3 8.8 19.5 1.5 1.6 1.2 10.4 1.2 19.9 1.2 1.3 1.6 1.3 1.2 1.2 4.1 1.6 1.3 4.2 1.2 1.5 3.9 2.7 0.0 1.2 0.0 1.3 1.2 0.2 0.4 0.0 0.0 0.2 0.0 3.6 0.1 2.2 1.0 0.9 14.8 0.0 0.0 1.2 0.1 0.1 0.2 0.6 0.5 0.9 3.6 1.6 0.0 0.0 4.3 0.0 0.0 2.5 2.9 0.3 3.6 1.6 0.0 0.7 0.7 0.3 0.0 0.5 0.5 0.0 3.1 1.9 0.0 0.5 1.5 0.4 4.4 4.5 9.8 2.9 5.1 0.2 0.1 26.2 13.0 0.5 0.9 2.6 2.4 1.3 0.0 1.8 2.8 2.0 0.4 10.7 8.5 2.1 3.3 2.0 0.1 0.0 0.2 0.0 0.0 0.2 3.6 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 2.0 0.1 20.4 13.6 51.0 34.3 16.1 16.3 8.8 19.5 19.9 2.7 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavourable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 15.2 12.4 12.5 9.6 16.4 23.6 13.9 16.3 11.8 15.1 16.9 14.2 5.0 23.9 7.7 19.9 7.6 15.1 9.3 16.0 11.5 8.1 10.8 14.0 13.0 14.3 5.8 13.9 18.1 12.1 25.3 20.3 14.1 8.3 7.3 18.0 10.4 8.4 6.0 10.3 14.2 12.4 21.0 4.5 7.8 8.3 17.5 10.4 19.2 25.1 8.2 11.4 5.7 13.7 29.3 18.9 15.3 16.1 10.0 8.9 8.7 19.6 7.9 12.1 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favourable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favourable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.6 3.5 20.7 8.3 36.1 12.3 1.8 1.1 72.5 3.8 5.3 19.0 0.2 9.1 3.6 4.9 2.2 4.9 3.1 2.1 19.7 9.3 3.6 6.4 4.6 9.9 13.0 33.6 4.6 14.3 7.1 7.7 2.6 13.0 2.7 4.4 0.7 4.6 4.2 2.6 6.9 8.8 3.0 7.9 11.4 3.9 2.1 12.5 1.8 2.4 0.3 9.4 3.3 2.4 4.4 10.3 23.2 9.7 5.8 8.4 3.1 3.3 4.9 2.3 10.0 6.8 5.5 5.4 3.4 2.2 2.4 3.4 4.9 4.6 8.6 5.1 3.4 1.8 3.3 1.9 1.7 7.3 4.1 3.9 5.2 7.8 5.7 2.1 13.2 6.2 5.7 3.6 1.4 1.0 4.0 5.7 2.7 5.9 4.4 6.9 2.4 6.1 11.9 1.9 6.3 1.8 1.5 3.7 6.1 4.7 2.8 2.0 3.1 4.9 3.9 3.1 3.3 12.9 1.4 6.2 8.3 7.9 6.7 11.1 2.8 0.1 4.5 9.4 8.4 5.6 6.2 4.1 4.7 3.3 2.1 4.4 3.7 6.4 23.2 5.8 9.7 10.3 5.0 3.1 20.7 36.1 1.1 72.5 19.7 9.3 13.0 33.6 13.0 12.5 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 17.5;HDLM-2: 22.2;HEL: 18.4;RT4: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favourable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 16.2 12.9 10.2 6.9 11.8 2.5 12.6 6.2 19.4 13.9 6.9 6.3 6.3 6.3 14.4 8.9 31.2 11.6 9.7 24.5 9.9 8.1 14.2 9.5 13.1 5.0 6.5 9.2 20.2 5.9 35.6 16.7 18.4 11.1 10.1 5.3 5.7 13.7 8.7 12.7 16.9 6.8 11.4 5.6 6.0 8.2 10.7 5.0 37.5 8.1 21.8 20.6 13.6 22.3 3.4 1.1 12.1 0.9 2.4 7.5 1.4 7.4 4.1 2.0 0.1 6.8 6.1 4.9 1.7 2.6 0.6 0.5 3.8 2.0 0.5 3.5 1.4 6.7 6.3 17.5 0.7 22.2 2.0 18.4 2.3 1.6 0.5 0.0 6.5 10.1 9.7 3.8 7.7 13.9 1.7 2.1 4.7 6.5 2.6 0.1 1.3 3.3 0.6 1.8 0.4 1.6 22.5 3.0 2.4 2.2 0.9 0.1 1.5 0.1 13.2 1.6 2.2 2.4 2.8 5.4 2.4 0.1 4.2 0.0 1.3 12.1 0.4 0.8 1.2 0.5 2.9 3.4 4.7 1.2 0.4 2.1 5.0 2.1 4.1 2.4 0.9 1.1 7.5 1.4 10.2 11.8 6.2 19.4 9.9 8.1 6.5 9.2 11.1 5.0 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27186924 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm Nucleoplasm "HPA027175: AB_1853591, HPA054273: " "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavourable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavourable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 9.1 7.0 3.6 8.9 6.1 21.1 8.3 4.0 7.5 7.4 7.6 3.8 5.7 5.7 6.0 6.7 12.3 5.4 5.3 5.6 6.8 4.5 6.5 7.1 10.2 14.8 5.4 5.7 7.0 12.7 6.7 6.3 14.2 6.7 5.5 7.1 5.6 8.0 4.7 4.0 10.1 10.0 6.1 5.6 8.7 6.2 11.3 2.3 21.1 6.5 4.3 12.3 8.7 7.5 3.9 2.6 5.6 4.9 2.3 4.0 1.8 11.7 9.5 18.1 6.7 2.8 4.1 10.7 17.6 7.4 29.2 36.0 11.4 11.8 9.4 6.7 7.4 11.4 11.5 6.9 20.8 8.0 11.1 11.1 6.6 6.6 1.6 4.2 8.4 2.4 3.1 17.6 3.5 6.3 8.4 21.3 17.7 7.8 13.7 4.7 13.4 3.9 8.8 30.2 7.7 7.2 4.4 8.1 11.6 11.1 7.4 7.8 7.5 9.0 5.4 7.3 15.3 18.6 15.4 2.6 4.1 13.9 8.0 12.9 6.0 0.1 4.4 3.8 2.0 4.3 3.0 2.6 2.5 1.8 2.5 3.9 2.5 2.3 5.6 2.3 4.9 2.6 4.0 1.8 3.6 6.1 4.0 7.5 6.8 4.5 5.4 5.7 6.7 2.3 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808176-68850686 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 93.7;U-698: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303" Supported Supported Nucleoplasm Nucleoplasm "CAB000086: AB_563872, CAB016303: AB_627920" "unprognostic (1.16e-1)" "prognostic favourable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favourable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 16.6 15.3 11.1 12.5 10.8 23.1 12.5 12.0 11.3 13.1 16.6 13.6 11.9 5.2 8.8 9.4 14.2 12.6 12.3 9.0 8.8 8.6 11.2 25.7 15.9 13.3 14.2 7.1 11.0 21.4 11.4 10.4 24.5 11.9 12.6 21.5 7.8 10.5 11.1 19.5 9.8 7.2 10.8 10.8 15.3 9.8 6.5 11.5 29.5 13.6 10.8 14.1 13.5 12.6 4.9 4.0 19.3 6.4 3.6 4.4 3.0 3.1 7.3 7.7 3.9 10.0 9.3 39.4 8.7 8.7 4.6 7.4 4.4 1.4 32.6 2.4 5.7 1.8 5.2 93.7 7.5 8.6 3.7 6.0 6.2 19.8 9.8 5.3 5.5 14.3 8.0 18.4 12.5 12.9 6.1 7.9 8.8 5.0 7.0 1.7 6.5 1.4 24.8 5.3 2.7 2.8 26.1 5.9 3.4 5.5 4.3 1.9 10.1 3.5 13.8 3.5 6.7 2.9 3.1 12.1 7.6 90.1 5.4 2.1 14.4 5.3 5.4 4.8 4.4 4.0 3.9 4.7 3.7 4.1 2.8 4.9 4.0 3.7 19.3 3.6 6.4 4.0 3.8 3.0 11.1 10.8 12.0 11.3 8.8 8.6 14.2 7.1 11.9 11.5 MED1 "CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2" ENSG00000125686 "Mediator complex subunit 1" Q15648 17 39404285-39451286 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017696, HPA052818" Approved Supported Nucleoplasm 170000 Nucleoplasm "CAB017696: AB_1128703, HPA052818: " "unprognostic (1.77e-1)" "unprognostic (1.63e-1)" "unprognostic (9.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.50e-1)" "unprognostic (7.86e-2)" "unprognostic (1.95e-3)" "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (2.00e-1)" "unprognostic (5.94e-2)" "unprognostic (9.40e-2)" "unprognostic (5.79e-2)" 16.4 13.8 11.8 14.8 13.7 15.5 15.1 19.8 16.5 16.9 14.6 18.8 9.3 10.3 17.9 9.7 15.0 14.3 10.9 12.8 11.6 10.5 13.0 13.3 12.3 17.7 12.0 10.3 22.2 16.2 34.5 21.1 16.5 14.5 12.5 14.2 16.5 13.4 11.6 19.5 16.1 14.1 17.1 14.0 20.4 13.0 15.1 12.1 34.1 13.2 12.1 22.5 16.6 13.4 6.6 4.9 4.4 4.0 5.0 6.1 2.7 8.0 10.7 13.5 9.2 9.9 10.1 10.9 9.8 10.6 13.5 13.2 10.3 8.0 21.5 11.2 12.2 15.9 16.1 9.7 21.5 20.7 13.5 13.5 10.2 10.2 10.7 24.1 14.3 9.5 9.8 16.6 24.2 11.4 17.3 11.7 10.9 4.5 22.4 9.1 8.7 6.4 16.9 18.2 9.2 7.9 9.3 8.6 9.8 13.0 85.6 11.2 15.8 13.8 10.1 10.5 13.1 11.6 17.2 10.7 14.3 22.2 10.3 11.9 12.8 3.2 4.0 4.4 5.2 3.9 5.8 6.6 5.5 5.8 4.0 6.4 5.4 6.1 3.3 5.0 2.6 4.9 3.3 2.7 11.8 13.7 19.8 16.5 11.6 10.5 12.0 10.3 14.5 12.1 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavourable (2.91e-7)" "prognostic unfavourable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.4 18.2 24.6 14.5 3.4 5.9 14.3 26.3 18.6 36.9 45.6 14.0 14.0 11.9 8.5 12.9 12.2 21.4 16.5 40.8 32.3 8.5 9.3 21.7 13.9 1.3 14.4 11.8 2.1 3.0 28.5 16.2 18.6 11.9 19.0 30.2 11.8 17.9 6.8 19.6 14.3 16.6 16.6 7.6 11.3 12.0 16.7 12.4 14.0 13.5 8.5 11.3 6.9 9.1 19.9 25.2 16.8 23.9 3.7 13.5 17.8 12.6 10.7 27.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase like 1" Q9UBP6 12 57768471-57772793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "RH-30: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm Nucleoplasm "HPA020914: AB_1853830, HPA050450: " "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavourable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" 12.2 16.6 6.7 13.8 8.8 8.4 12.3 2.2 6.9 7.6 7.6 4.5 10.8 3.3 9.4 21.2 10.3 9.0 10.7 8.1 5.8 5.0 20.9 15.3 7.7 8.8 7.4 4.6 17.6 34.9 10.9 10.6 8.3 6.5 11.0 10.3 5.3 17.9 17.2 20.4 8.5 5.7 10.5 5.0 8.2 7.3 11.4 5.4 4.5 15.1 15.6 9.8 8.8 7.8 6.1 12.6 0.7 6.7 7.3 18.6 5.1 5.9 11.0 4.6 4.2 6.2 4.3 6.3 6.5 5.8 10.9 5.9 7.6 8.4 7.2 12.0 7.8 7.2 7.1 10.0 10.6 4.3 8.2 8.4 4.2 9.3 4.4 9.1 4.4 3.8 9.1 12.2 8.5 5.7 7.7 7.3 5.5 11.7 6.3 10.9 10.8 11.0 5.6 77.0 10.7 9.5 7.5 4.9 4.4 6.7 7.5 6.0 9.8 8.6 4.3 4.4 4.9 7.7 8.5 3.4 2.5 8.8 6.2 6.5 9.1 0.0 4.7 0.0 5.3 6.7 18.6 4.7 6.9 6.5 10.3 6.1 9.5 9.2 0.7 7.3 1.1 12.6 3.3 5.1 6.7 8.8 2.2 6.9 5.8 5.0 7.4 4.6 6.5 5.4 METTL3 "M6A, MT-A70, Spo8" ENSG00000165819 "Methyltransferase like 3" Q86U44 14 21498133-21511375 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, Immunity, Innate immunity, Spermatogenesis" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.19e-5)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "prognostic favourable (2.78e-4)" "prognostic favourable (2.72e-4)" "unprognostic (4.52e-2)" "unprognostic (4.64e-3)" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (5.36e-2)" "unprognostic (1.22e-1)" 13.1 21.0 15.7 18.3 20.4 6.8 17.4 27.1 16.4 13.5 12.8 16.3 20.4 7.7 17.1 19.8 14.3 20.9 11.2 17.3 16.3 8.6 14.6 14.0 14.2 18.4 21.7 15.2 18.2 14.2 25.8 21.3 16.0 16.3 19.3 13.9 12.2 17.0 19.3 18.8 17.0 11.9 17.6 13.8 17.5 12.9 21.6 20.6 15.4 19.2 13.3 21.8 15.1 14.8 13.0 12.6 7.7 10.3 15.3 14.3 8.1 16.8 25.2 24.0 9.6 18.6 15.4 12.1 15.5 11.4 18.6 21.9 9.5 20.0 17.6 10.0 9.6 17.9 29.3 15.3 29.5 16.6 17.4 10.9 13.9 37.6 7.6 14.7 12.4 11.5 13.5 11.5 13.6 24.2 13.4 10.1 24.6 12.4 13.0 11.7 20.4 31.1 13.1 19.0 15.6 17.0 11.3 14.9 16.1 16.9 22.3 15.8 17.6 9.7 15.8 6.6 11.1 12.1 10.5 10.7 13.3 12.2 8.1 11.8 14.0 5.1 8.1 7.7 8.7 10.3 12.7 13.0 10.5 9.6 10.5 10.3 11.0 9.7 0.9 15.3 8.4 12.6 14.3 8.1 15.7 20.4 27.1 16.4 16.3 8.6 21.7 15.2 16.3 20.6 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 155.5" "Cell line enhanced" "Detected in some" "A549: 3.6;BJ hTERT+: 3.2;HL-60: 5.3;U-937: 8.5;WM-115: 2.0" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "neutrophil: 14.1" "Lineage enriched" "Detected in single" 104 "granulocytes: 14.1" "Region enriched" "Detected in single" 12 "olfactory region: 3.1" HPA002270 Enhanced 68000 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favourable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 0.9 0.2 0.3 0.8 0.2 6.9 0.3 0.2 0.2 0.2 59.4 0.1 7.6 25.2 0.2 36.0 0.2 1.0 0.1 0.3 0.2 0.2 8.7 0.4 2.1 0.1 0.3 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.0 0.1 0.2 3.2 0.2 0.1 155.5 0.1 0.3 8.3 0.7 4.3 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 3.6 0.2 0.1 0.0 0.0 0.4 0.1 3.2 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.3 1.0 0.4 0.1 0.3 0.0 0.1 0.0 8.5 2.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.1 MGEA5 "MEA5, NCOAT, OGA" ENSG00000198408 "Meningioma expressed antigen 5 (hyaluronidase)" O60502 10 101784443-101818465 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol Cytosol "HPA036141: AB_10672079, HPA076501: " "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 29.5 17.5 51.9 27.4 54.4 49.3 35.5 58.9 51.4 24.5 27.0 29.0 20.9 17.6 29.9 36.8 26.0 23.3 19.1 27.4 46.0 29.8 27.7 28.6 24.0 40.1 30.7 43.6 33.8 20.9 53.3 22.1 25.5 42.6 31.6 26.5 30.7 24.4 26.3 25.4 36.6 28.5 37.4 29.5 35.2 23.9 21.9 35.4 32.9 25.9 11.8 39.5 34.3 26.7 8.1 3.3 14.7 5.6 6.8 7.1 1.4 30.6 15.6 22.9 44.3 14.7 35.7 15.9 21.6 21.9 10.1 17.4 11.5 19.7 20.5 15.8 25.7 22.1 21.3 27.2 21.5 30.0 14.6 20.5 21.8 8.9 15.9 15.1 11.6 34.5 30.6 17.3 41.3 18.7 14.4 38.1 17.1 15.6 15.9 15.8 12.6 15.8 22.2 25.2 15.0 16.9 27.8 9.9 17.6 19.3 10.5 27.0 27.6 16.5 28.3 15.6 15.1 22.5 24.7 19.1 30.3 16.4 19.6 26.0 8.5 10.5 2.1 6.8 7.1 2.0 5.6 6.4 4.9 6.1 1.3 8.1 6.8 5.7 14.7 6.8 5.6 3.3 4.5 1.4 51.9 54.4 58.9 51.4 46.0 29.8 30.7 43.6 42.6 35.4 MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467184-129768007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: , HPA032136: , HPA069497: " "unprognostic (1.10e-1)" "prognostic favourable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favourable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" 11.7 11.3 7.4 15.5 7.6 7.1 11.3 3.5 9.1 8.3 12.2 10.0 19.6 10.8 15.3 17.1 9.9 15.2 14.1 10.5 7.1 7.1 12.6 45.6 7.5 11.6 8.6 6.6 12.3 16.5 5.7 5.8 4.5 9.2 11.2 3.4 11.8 14.9 24.5 14.4 9.2 9.6 10.9 8.1 8.6 9.9 11.7 3.9 16.0 10.2 14.9 14.7 12.6 13.0 20.3 17.7 6.5 15.3 18.2 21.2 16.6 0.0 2.6 2.8 13.3 5.8 12.1 10.4 5.9 6.6 4.3 4.2 16.2 17.3 12.1 9.5 7.6 7.9 1.7 6.3 1.9 0.0 1.0 2.4 5.9 10.3 9.0 0.2 6.9 7.7 0.0 2.5 0.0 0.0 0.0 8.5 5.3 21.8 9.5 12.4 0.6 10.4 11.0 0.0 4.7 7.9 5.9 2.8 7.0 7.1 2.9 0.0 11.4 9.4 0.0 5.7 2.9 0.0 0.0 0.0 0.0 6.1 0.0 3.9 0.0 2.6 15.3 6.5 19.1 14.8 18.6 20.3 17.5 17.8 15.8 19.9 17.6 18.9 1.8 18.2 13.7 17.7 21.2 16.6 7.4 7.6 3.5 9.1 7.1 7.1 8.6 6.6 9.2 3.9 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 16.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 16.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Approved Vesicles Vesicles "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 18.7 23.1 22.9 24.0 24.3 29.7 19.9 43.1 37.6 16.3 16.6 28.7 16.8 28.9 23.7 13.8 14.7 20.9 20.2 20.7 24.3 18.6 15.9 30.4 21.6 22.2 27.9 21.5 21.3 34.9 19.7 21.5 18.8 18.6 19.0 11.6 20.7 23.8 22.9 29.9 13.5 28.6 20.0 17.2 26.2 25.2 11.5 24.5 12.9 19.7 10.4 11.0 18.7 14.2 1.7 4.1 16.6 3.9 1.4 3.3 2.9 5.2 25.1 13.0 13.3 7.8 7.6 17.8 11.3 8.0 9.6 8.1 16.6 12.6 15.6 14.7 13.7 8.5 10.4 9.3 2.8 21.6 11.5 8.5 17.6 22.8 14.3 12.3 21.2 14.1 6.1 13.3 5.7 9.1 12.4 11.4 6.5 23.1 12.8 16.5 19.2 11.0 23.5 6.8 20.9 8.4 15.4 20.9 17.4 18.8 20.3 11.3 12.3 12.2 16.1 17.8 9.9 50.1 9.7 18.2 14.1 10.5 7.6 12.4 12.8 4.5 3.5 3.4 2.7 3.9 2.5 1.4 1.5 2.3 2.3 1.7 3.3 2.0 16.6 1.4 2.4 4.1 1.7 2.9 22.9 24.3 43.1 37.6 24.3 18.6 27.9 21.5 18.6 24.5 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 12.1 9.1 15.3 7.9 20.6 5.9 15.7 16.1 17.4 16.6 10.9 16.3 9.7 6.9 19.1 13.7 11.4 11.5 12.0 9.4 16.3 12.9 15.7 14.1 10.1 9.6 17.4 16.5 17.2 11.7 18.4 11.5 14.9 15.5 14.7 10.1 14.6 12.0 12.6 9.6 12.5 8.4 17.9 13.8 9.4 10.7 11.5 18.1 13.9 19.1 9.8 10.6 13.0 13.8 1.2 1.2 3.5 1.7 2.5 2.0 0.6 8.4 3.3 16.5 11.4 8.8 10.6 3.9 6.8 7.6 4.9 7.1 4.9 3.1 7.2 6.3 9.4 5.7 9.6 9.2 11.1 9.4 4.5 8.0 4.3 6.8 7.2 16.3 3.4 6.8 10.2 5.7 14.7 12.2 11.0 21.3 7.5 4.1 7.8 6.2 4.2 4.4 51.5 13.6 17.8 8.3 7.5 5.4 13.3 11.7 5.4 6.0 3.9 10.7 10.4 12.5 6.3 5.2 9.0 11.2 3.9 11.1 5.3 10.4 7.4 3.5 1.7 0.6 1.0 0.9 1.2 1.2 1.5 1.0 0.6 0.6 1.2 0.9 1.5 2.5 0.5 1.2 2.0 0.6 15.3 20.6 16.1 17.4 16.3 12.9 17.4 16.5 15.5 18.1 MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "Mindbomb E3 ubiquitin protein ligase 2" Q96AX9 1 1615415-1630610 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 72.5" "Cell line enhanced" "Detected in many" "HaCaT: 13.1;SCLC-21H: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced "HPA068322: " "unprognostic (3.93e-2)" "unprognostic (6.02e-2)" "unprognostic (2.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.17e-2)" "unprognostic (2.22e-3)" "unprognostic (1.29e-1)" "unprognostic (3.58e-2)" "unprognostic (2.49e-1)" "unprognostic (1.01e-2)" 6.4 3.9 8.7 6.4 10.0 4.5 4.7 8.8 11.5 4.8 6.9 7.1 4.7 5.3 5.1 5.4 11.4 4.1 3.7 6.1 9.1 7.9 5.5 6.2 5.1 3.7 5.3 7.1 5.8 7.0 3.7 9.4 4.0 5.7 4.7 3.7 6.6 5.4 6.5 72.5 9.6 4.6 5.4 3.4 9.0 8.5 5.2 5.8 7.4 5.9 9.7 4.1 4.5 4.1 2.9 9.2 1.9 0.1 7.3 4.7 1.0 6.5 0.9 0.4 1.5 1.7 0.6 9.1 3.1 1.4 1.0 2.3 1.3 1.6 0.7 4.4 0.9 13.1 0.5 2.0 0.0 3.4 5.6 0.5 1.9 1.2 2.4 0.8 2.2 1.4 1.4 0.6 0.2 0.5 2.6 1.2 0.2 1.0 3.6 8.3 1.1 10.4 6.1 1.9 8.9 0.1 0.8 14.0 5.1 5.2 0.7 5.0 1.0 3.2 0.6 0.9 2.1 5.1 0.9 6.8 2.0 1.8 2.3 2.6 1.1 0.0 0.1 1.9 4.3 0.1 4.3 2.6 3.3 4.7 0.0 2.9 3.9 2.9 0.5 7.3 0.0 9.2 2.3 1.0 8.7 10.0 8.8 11.5 9.1 7.9 5.3 7.1 5.7 5.8 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 56.8;AF22: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Approved "Centriolar satellite" "Centriolar satellite" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 13.4 3.6 6.5 10.4 8.4 0.3 8.6 16.3 7.1 17.5 21.5 3.8 11.7 7.7 17.9 11.3 12.2 7.7 13.1 13.2 6.2 4.2 7.9 4.9 10.4 4.2 4.5 3.7 12.0 4.8 2.7 6.6 7.8 4.9 14.6 12.8 15.9 7.1 19.1 2.8 3.9 8.7 30.6 2.6 1.3 5.3 6.5 4.1 0.8 6.2 7.1 5.8 17.1 20.5 1.0 0.7 3.3 0.0 0.0 0.1 0.1 12.2 56.8 43.0 6.6 2.5 3.6 5.3 7.7 6.4 7.9 8.1 10.4 3.7 4.1 2.5 7.0 8.4 3.5 5.3 5.9 0.2 5.1 0.9 8.1 0.2 1.1 0.0 0.2 4.1 2.8 5.2 5.5 7.6 0.6 0.7 3.1 1.9 1.6 0.1 13.7 4.1 1.2 11.0 0.0 5.8 11.3 3.0 1.1 3.3 9.7 3.6 6.7 0.0 4.8 2.6 0.3 13.3 6.7 0.6 0.3 0.1 5.6 0.0 12.8 0.1 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.1 6.5 8.4 16.3 5.2 6.2 4.2 4.5 3.7 4.9 4.1 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833388-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved "HPA056296: " "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favourable (2.77e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 12.7 14.8 31.4 18.2 46.8 14.9 14.2 30.8 43.5 15.2 26.0 32.6 8.8 33.1 12.4 7.7 40.0 14.3 15.6 9.0 28.4 12.8 13.8 10.0 23.3 17.1 28.6 27.3 27.5 21.5 16.5 15.4 17.4 29.0 14.3 20.7 14.5 21.1 11.3 8.3 47.3 31.1 11.4 24.8 20.0 22.3 14.5 30.9 9.0 12.7 14.6 16.8 14.9 24.1 2.6 1.2 6.4 1.6 0.3 3.0 2.3 18.4 33.9 7.9 12.8 12.6 9.2 22.8 14.8 13.5 11.8 10.0 12.8 12.9 13.2 17.1 15.5 37.6 5.9 26.6 5.8 18.9 16.5 9.4 21.5 10.0 8.3 3.5 18.5 9.8 20.0 11.1 10.3 12.7 10.1 11.5 8.7 11.0 5.6 8.0 6.2 11.0 7.0 6.5 8.0 18.1 19.0 8.3 6.6 15.3 12.8 9.6 11.5 4.9 18.4 12.6 5.7 21.3 14.0 6.6 5.3 2.7 11.3 7.6 8.5 0.0 1.6 6.4 2.7 1.6 3.0 2.6 2.8 2.1 1.2 1.5 2.0 0.8 1.3 0.3 0.8 0.8 2.8 2.3 31.4 46.8 30.8 43.5 28.4 12.8 28.6 27.3 29.0 30.9 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: " "unprognostic (4.05e-3)" "prognostic favourable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavourable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavourable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.3 13.1 8.7 9.6 7.8 11.6 11.6 9.8 9.8 11.9 16.2 15.1 8.0 12.8 12.1 9.8 23.5 14.5 16.0 12.7 21.9 12.9 27.0 15.0 12.9 12.2 14.4 22.0 15.2 11.1 15.5 8.5 13.9 14.1 9.4 6.4 12.7 10.3 12.9 5.9 15.6 9.5 18.2 12.8 12.7 20.3 6.1 5.5 18.9 17.1 15.8 11.5 16.1 11.2 4.3 0.9 13.5 10.9 8.0 13.3 10.9 8.4 18.6 7.9 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Cell line enhanced" "Detected in all" "HHSteC: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: " "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favourable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favourable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.1 14.8 6.3 13.8 46.9 17.0 14.2 7.8 5.6 5.6 5.7 9.5 23.1 18.6 10.8 15.7 16.3 7.9 22.8 2.5 25.3 7.4 7.5 12.5 10.1 78.8 14.7 13.6 18.1 55.5 10.6 22.6 13.2 12.9 33.3 3.8 7.7 8.8 12.3 16.5 16.2 16.9 1.8 23.5 9.9 8.6 8.7 10.4 18.3 27.1 33.4 11.2 18.3 19.8 2.0 8.0 8.2 9.3 54.3 21.0 18.2 16.5 11.1 3.7 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453040-140479569 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA000567: AB_1079299" "unprognostic (9.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (4.87e-3)" "unprognostic (1.24e-2)" "unprognostic (8.02e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-3)" "unprognostic (5.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.22e-2)" 16.8 17.6 26.8 20.8 28.8 69.9 20.1 37.2 32.6 20.4 39.6 16.1 19.7 28.4 20.1 18.6 23.3 22.2 22.4 38.5 24.9 29.8 20.6 17.5 23.6 18.3 25.7 23.3 24.9 27.3 28.2 21.5 31.7 29.4 21.0 33.7 19.4 24.8 23.1 38.5 24.4 26.6 26.3 20.5 22.5 21.7 95.4 20.2 21.0 23.6 18.8 22.3 25.3 36.4 13.1 7.5 39.3 10.5 12.8 17.8 6.4 27.9 21.6 16.9 25.0 26.8 23.5 23.9 19.3 25.1 15.2 17.6 8.8 29.5 20.3 30.3 18.8 13.6 19.0 21.2 19.3 40.2 16.5 21.1 13.0 16.3 21.6 18.0 32.7 23.4 32.0 17.1 16.2 15.1 16.6 25.7 14.6 24.1 21.1 32.4 43.4 16.0 15.3 14.5 31.1 24.4 32.4 23.4 24.2 24.2 32.8 34.5 16.1 15.7 21.4 10.7 8.5 26.1 17.6 61.3 44.9 17.8 30.6 28.4 22.0 19.4 9.2 39.3 6.7 8.7 8.0 13.1 13.0 10.1 7.5 10.9 17.8 11.3 18.1 12.8 10.5 2.5 14.0 6.4 26.8 28.8 37.2 32.6 24.9 29.8 25.7 23.3 29.4 20.2 MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557014-12583713 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037559: AB_10672460, HPA037560: AB_10696936" "unprognostic (4.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-2)" "unprognostic (5.99e-2)" "unprognostic (3.89e-2)" "unprognostic (1.47e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (4.38e-1)" "unprognostic (8.49e-2)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-3)" "prognostic favourable (6.04e-4)" "unprognostic (3.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-2)" "unprognostic (3.32e-2)" 13.7 10.4 15.1 11.1 18.3 16.4 11.6 29.3 19.5 13.7 12.7 12.4 16.1 12.5 15.2 12.3 16.2 13.1 10.9 26.3 14.0 15.1 13.7 12.5 12.1 12.6 15.2 14.8 20.8 26.6 17.3 11.9 14.4 16.0 11.3 11.5 13.2 12.8 13.1 24.5 12.8 10.9 15.9 16.2 10.1 11.7 46.1 14.7 15.4 18.2 17.0 13.7 13.0 12.6 21.3 19.0 30.0 20.3 25.3 26.2 18.7 10.7 12.4 14.8 11.1 23.2 22.6 28.7 16.6 17.8 21.2 17.8 12.0 10.7 15.2 9.5 18.3 6.6 19.3 16.3 18.9 17.2 16.2 21.7 14.2 16.0 26.7 21.3 9.9 25.1 15.2 24.6 15.6 17.4 20.2 21.6 18.2 15.1 26.1 11.1 9.9 21.8 25.2 14.3 17.1 14.9 14.2 8.7 14.7 14.4 7.4 14.8 16.7 18.9 17.5 14.5 14.3 17.2 22.5 16.4 33.6 32.7 15.7 25.5 21.8 18.9 17.2 30.0 21.5 15.6 26.2 21.3 22.1 22.0 19.0 16.4 23.9 22.3 15.0 25.3 20.3 15.1 23.4 18.7 15.1 18.3 29.3 19.2 14.0 15.1 15.2 14.8 16.0 14.7 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565678-23630075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell line enhanced" "Detected in many" "K-562: 17.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 4 "T-cells: 5.7" "Low region specificity" "Detected in many" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 1.0 0.7 5.1 1.2 10.4 4.0 1.2 1.0 11.1 0.5 1.1 8.4 0.0 1.3 1.3 3.2 5.6 0.9 0.8 0.8 6.4 3.4 1.1 0.7 1.0 1.9 14.4 3.0 1.2 1.7 0.5 3.8 8.5 5.1 1.2 0.8 3.1 5.2 1.0 1.4 1.2 1.9 0.8 8.2 1.5 0.9 5.7 13.3 5.0 0.9 1.1 1.7 0.7 0.6 1.0 0.9 1.3 0.5 0.4 5.7 0.7 4.7 3.4 3.0 3.1 0.0 0.0 7.1 0.3 0.0 2.9 2.0 8.5 0.0 0.2 0.1 0.0 8.2 1.3 0.0 0.7 0.0 0.3 6.8 9.1 0.3 0.2 8.0 6.1 0.1 0.0 6.0 0.0 0.0 17.5 7.5 0.8 0.0 8.4 3.5 0.0 10.4 6.0 1.1 4.2 0.0 0.1 0.7 2.4 0.0 3.4 0.0 2.7 2.4 0.1 8.0 6.7 0.4 5.6 9.4 11.5 5.6 4.7 0.1 0.1 1.3 0.5 0.4 1.8 0.2 1.0 1.0 0.6 1.4 0.2 0.9 2.0 5.7 1.3 0.4 0.3 0.9 0.4 0.7 5.1 10.4 1.0 6.8 6.4 3.4 14.4 3.0 5.1 13.3 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 50.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favourable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 18.5 4.7 5.2 15.1 8.9 21.6 13.2 2.9 7.9 6.4 8.0 3.2 5.3 8.5 7.5 3.8 11.5 5.2 9.1 6.8 6.4 3.5 7.4 6.7 17.3 14.8 10.5 1.8 2.8 8.2 1.6 3.0 7.1 8.1 6.3 9.2 6.5 12.6 4.3 2.3 3.6 10.0 6.0 11.2 26.2 8.2 1.9 8.4 4.3 6.5 4.9 10.4 9.2 50.4 4.2 9.2 25.2 17.7 1.7 8.1 7.1 6.5 12.1 0.1 0.1 3.1 6.7 0.1 8.4 7.3 8.0 11.8 7.0 13.1 0.1 9.7 7.1 10.5 2.2 12.2 3.0 4.1 0.3 9.1 9.0 7.9 2.3 5.9 9.5 4.4 1.2 8.5 3.0 19.2 1.3 1.3 6.2 10.8 3.4 11.9 1.0 14.9 6.6 0.9 11.7 11.3 4.8 0.5 0.4 6.7 4.4 3.7 3.2 6.3 20.9 4.0 2.4 3.6 5.7 5.6 19.1 1.6 7.2 21.0 1.9 8.3 17.7 21.7 5.8 10.6 7.9 4.2 6.5 6.0 9.2 2.8 3.6 5.5 25.2 1.7 10.2 0.5 8.1 7.1 5.2 8.9 2.9 7.9 6.4 3.5 10.5 1.8 8.1 8.4 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305200 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 28.0;hTEC/SVTERT24-B: 71.2;NB-4: 88.6;U-138 MG: 37.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027292 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 5.9 6.8 12.9 2.7 17.3 3.7 7.8 9.7 15.9 7.6 3.6 8.7 6.2 4.7 7.6 10.2 3.9 26.4 6.4 8.3 13.5 10.2 7.7 3.6 6.1 2.5 6.0 13.7 12.4 8.6 9.4 22.1 3.6 16.6 5.1 3.0 15.2 6.1 5.4 1.9 8.6 4.1 5.9 6.2 3.8 11.7 45.0 6.2 0.4 11.7 2.3 2.2 6.2 3.9 0.7 3.9 0.9 1.1 10.6 2.4 1.3 3.3 3.0 0.4 1.7 0.7 2.5 0.7 6.8 2.0 9.9 11.9 0.2 8.3 2.5 0.5 1.3 0.7 0.6 3.5 28.0 2.8 2.5 0.6 0.3 2.2 3.0 0.2 3.3 2.1 0.9 71.2 6.6 0.3 0.6 0.1 6.4 2.2 0.2 88.6 0.1 7.2 0.4 0.1 0.0 4.0 0.1 1.1 0.7 1.2 0.4 19.2 2.0 0.2 0.2 37.6 1.9 1.4 2.1 0.2 0.4 0.2 7.5 0.2 17.0 0.0 1.1 0.0 0.7 0.7 1.2 0.0 0.5 1.9 3.9 0.7 1.1 2.4 0.9 10.6 0.1 0.0 0.0 1.3 12.9 17.3 9.7 15.9 13.5 10.2 6.0 13.7 16.6 6.2 MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (3.28e-1)" 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003634 Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA003634: AB_1851388" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 12.4 23.4 13.9 18.4 14.8 13.7 17.6 18.1 15.7 10.6 15.2 9.8 17.5 13.1 12.5 15.1 19.4 12.5 16.3 31.2 12.2 12.0 25.7 41.7 10.2 15.2 14.3 14.0 10.5 24.2 13.5 9.1 13.9 14.0 13.6 16.3 10.1 17.7 22.5 57.3 16.5 13.4 14.8 12.9 14.6 15.1 7.6 14.0 13.2 14.8 31.2 15.7 14.3 11.6 18.3 28.9 11.2 22.0 20.0 33.5 20.9 26.2 37.1 12.4 14.2 13.3 13.2 17.3 15.6 17.0 32.5 27.7 28.4 16.5 18.3 12.8 15.4 18.8 25.3 26.8 34.4 9.3 30.0 14.3 17.5 23.6 25.2 29.9 9.9 14.3 12.8 21.6 34.6 24.7 23.1 13.4 18.3 32.8 25.8 20.6 9.3 50.3 13.4 22.0 26.6 23.9 19.5 11.5 22.1 13.5 24.7 30.2 32.9 24.8 10.4 17.6 19.3 18.4 29.3 14.0 11.1 20.2 20.1 33.6 14.5 11.2 22.0 10.5 17.3 20.7 14.9 18.3 21.1 17.2 28.9 14.8 15.7 17.6 2.0 20.0 17.4 19.4 33.5 20.9 13.9 14.8 18.1 15.7 12.2 12.0 14.3 14.0 14.0 14.0 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054268-10428891 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Cell line enhanced" "Detected in many" "HMC-1: 15.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 78.4" "Cell type enhanced" "Detected in many" "eosinophil: 9.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.3;granulocytes: 9.0;monocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023804, HPA053069" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" 25000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA023804: AB_1853826, HPA053069: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 7.0 8.1 8.0 5.2 7.5 36.1 5.9 78.4 13.7 3.6 5.9 4.3 2.2 5.9 4.8 3.7 5.5 4.2 4.4 8.5 8.9 5.5 32.4 22.9 5.7 6.8 6.8 9.5 4.2 10.2 2.9 3.4 4.6 8.1 3.4 4.0 3.9 6.0 5.0 4.7 3.8 12.7 4.9 6.7 7.2 4.9 8.5 5.5 3.5 4.4 2.6 3.8 3.9 2.7 1.1 2.3 9.0 3.2 1.1 0.8 0.3 0.1 1.1 1.8 5.4 1.6 1.8 0.6 3.3 0.7 0.5 2.2 0.7 2.7 0.0 0.8 3.0 2.9 0.5 0.2 1.7 0.4 0.0 0.5 1.7 2.5 5.3 1.0 15.2 0.5 3.9 0.4 0.0 0.9 0.5 0.3 5.9 0.2 0.0 0.3 0.8 1.0 1.8 1.7 2.3 1.3 1.3 3.1 2.0 5.4 0.2 0.7 2.8 3.3 3.2 2.2 2.6 0.5 1.6 0.2 0.1 0.9 5.9 1.0 4.1 0.8 3.2 9.0 0.7 2.2 0.6 1.1 0.8 0.5 2.3 0.4 0.6 0.5 3.8 1.1 1.6 0.3 0.5 0.3 8.0 7.5 78.4 13.7 8.9 5.5 6.8 9.5 8.1 5.5 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795281-236903981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol Cytosol "HPA044474: AB_10966696, HPA054915: " "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavourable (5.75e-4)" "unprognostic (8.10e-2)" 14.5 11.4 9.9 13.2 13.5 7.6 13.6 14.8 14.4 16.9 16.4 16.2 16.0 7.5 18.1 27.3 10.4 18.4 16.3 21.9 9.4 9.8 21.2 9.5 11.7 14.3 12.6 12.8 24.7 20.8 27.4 12.4 17.5 13.0 14.0 8.9 17.7 11.1 17.3 27.0 15.4 11.7 23.3 12.1 13.9 14.9 20.1 12.1 20.8 22.4 11.1 13.2 18.4 14.4 3.3 1.6 3.0 2.0 2.3 5.8 2.1 9.9 6.7 8.2 6.8 15.3 14.1 9.7 8.7 7.8 9.6 10.0 6.3 7.6 22.1 8.1 9.8 6.9 10.6 7.8 11.5 10.2 9.1 13.0 8.9 11.6 10.3 20.6 8.1 20.1 4.9 12.7 12.2 12.7 18.7 10.4 8.0 6.9 10.7 6.6 11.0 3.6 11.7 14.6 14.2 6.9 11.5 6.7 18.7 9.8 7.2 8.8 10.2 8.4 16.4 15.9 6.1 12.2 11.2 22.6 7.0 12.9 10.3 13.0 15.6 2.7 1.6 3.0 3.2 2.0 5.8 2.7 4.2 4.5 1.5 3.3 5.0 4.0 0.1 2.3 1.5 1.6 2.9 2.1 9.9 13.5 14.8 14.4 9.4 9.8 12.6 12.8 13.0 12.1 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" Nucleoplasm "Intermediate filaments, Cytosol" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavourable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 12.2 12.3 11.2 10.5 13.8 5.4 9.7 15.6 14.3 10.8 10.4 24.1 11.5 10.3 17.3 15.9 10.5 11.3 13.3 15.8 14.2 12.9 22.0 23.9 14.9 11.4 18.1 9.6 13.6 13.6 9.4 13.1 11.6 16.6 10.8 11.9 13.6 11.3 7.4 34.6 10.5 11.5 14.2 22.1 9.3 9.2 8.4 12.5 8.1 14.7 9.9 13.5 13.6 8.8 4.6 4.8 4.6 6.8 3.4 11.4 4.2 9.3 8.8 4.7 10.4 17.9 5.8 13.3 14.5 8.6 7.2 8.2 13.2 7.5 15.7 13.9 11.6 6.0 7.2 7.1 13.6 9.9 8.1 7.5 30.5 7.0 10.9 11.4 3.2 9.4 6.5 12.2 9.0 4.7 9.7 11.9 4.2 1.8 7.3 5.8 3.5 9.8 6.0 5.0 6.6 7.8 7.3 7.3 0.9 25.4 18.5 15.9 5.7 8.9 7.2 16.8 10.6 12.9 11.3 17.7 5.8 12.9 12.2 25.2 8.9 4.6 5.1 4.1 5.5 6.8 9.5 4.6 9.2 7.9 4.8 4.1 5.4 5.1 0.1 3.4 5.4 2.7 11.4 4.2 11.2 13.8 15.6 14.3 14.2 12.9 18.1 9.6 16.6 12.5 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508161 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favourable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 13.3 15.9 10.3 12.9 12.3 20.6 20.4 9.2 22.2 13.1 15.8 19.0 8.0 11.6 18.2 10.7 17.2 17.0 18.5 26.2 11.7 12.5 20.5 20.1 16.3 12.1 16.8 9.5 17.5 26.8 21.9 13.0 21.6 17.6 13.9 13.3 14.3 15.3 18.1 26.7 17.4 19.5 17.0 11.7 13.6 15.2 14.1 11.6 18.5 15.1 14.6 14.0 16.3 13.6 23.2 26.0 31.9 30.4 25.2 32.1 27.5 16.9 16.4 9.5 19.6 20.6 11.6 10.3 16.9 20.2 21.0 20.3 10.1 28.2 12.8 18.9 23.8 25.9 17.0 24.4 15.3 12.7 13.5 9.8 11.1 14.6 24.3 13.4 16.8 18.9 32.2 21.5 22.4 13.7 12.7 15.6 22.8 8.6 8.0 9.0 9.7 15.7 7.9 11.9 16.5 24.7 9.5 9.7 14.3 15.1 16.2 20.7 11.4 12.9 15.4 20.5 11.8 17.8 15.1 18.3 15.9 13.8 16.1 18.2 19.0 26.3 26.5 31.9 30.9 30.4 32.1 23.2 23.6 31.4 26.0 21.5 27.1 26.3 24.0 25.2 25.4 20.1 32.1 27.5 10.3 12.3 9.2 22.2 11.7 12.5 16.8 9.5 17.6 11.6 MYCBP2 "FLJ10106, KIAA0916, PAM" ENSG00000005810 "MYC binding protein 2, E3 ubiquitin protein ligase" O75592 13 77044655-77327050 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA058807: " "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favourable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 28.0 13.4 31.0 26.1 28.8 24.1 22.4 31.3 32.7 15.5 10.9 8.1 11.5 8.0 16.2 26.7 18.9 11.7 11.1 13.5 24.1 18.6 12.3 13.2 12.4 29.8 15.3 31.1 22.8 12.6 14.5 17.2 9.6 20.0 17.9 11.5 9.6 12.9 12.4 13.7 57.6 13.6 13.2 14.0 24.1 10.3 14.1 16.2 18.6 11.6 12.6 30.7 13.3 34.0 8.3 4.6 3.3 3.7 4.2 7.3 2.5 7.7 3.9 4.8 5.2 24.0 10.7 2.8 4.9 7.3 4.3 5.5 3.5 4.0 22.1 3.1 9.6 7.1 8.2 9.0 5.8 8.7 8.2 18.7 8.0 7.2 8.2 39.2 6.6 12.0 7.5 3.9 7.9 9.7 3.9 7.0 7.6 4.6 10.7 26.5 2.5 5.0 12.2 4.9 5.3 7.2 7.7 7.5 3.5 5.9 8.6 4.4 3.2 30.1 12.8 4.1 3.4 2.7 4.7 7.6 5.2 15.7 8.3 32.3 4.1 2.0 3.5 3.2 5.8 3.7 5.1 7.9 6.5 5.0 3.2 8.3 7.3 5.8 3.3 4.2 2.5 4.6 7.3 2.5 31.0 28.8 31.3 32.7 24.1 18.6 15.3 31.1 20.0 16.2 MYLIP "IDOL, MIR" ENSG00000007944 "Myosin regulatory light chain interacting protein" Q8WY64 6 16129125-16148248 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 84.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.54e-1)" "unprognostic (4.84e-3)" "unprognostic (2.79e-1)" "unprognostic (9.65e-3)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-2)" "prognostic favourable (6.44e-6)" "unprognostic (2.75e-2)" "unprognostic (2.67e-2)" "unprognostic (5.44e-3)" "unprognostic (1.03e-2)" "prognostic favourable (3.67e-4)" "unprognostic (1.42e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "prognostic favourable (4.11e-5)" 23.4 12.5 7.3 10.3 10.6 44.2 19.5 5.4 11.4 28.5 14.4 18.9 16.4 7.5 31.8 16.1 12.1 22.2 19.1 9.0 8.6 6.1 13.1 3.5 19.0 19.4 12.9 8.8 22.3 10.5 9.8 6.1 84.0 7.4 20.1 9.7 20.2 16.2 20.9 20.6 16.7 15.7 18.0 7.0 23.5 14.8 15.2 12.2 8.8 39.1 10.9 15.7 19.0 33.7 4.9 1.4 14.2 2.3 3.2 8.4 1.5 1.9 4.0 1.6 2.0 17.1 4.6 4.4 1.4 3.4 3.4 7.5 11.4 2.1 9.1 7.3 2.2 5.1 8.0 2.5 2.9 3.3 8.3 6.1 4.3 2.1 2.5 4.2 6.1 7.3 3.3 1.7 1.4 7.9 17.6 10.8 1.3 7.6 0.1 20.6 4.8 3.7 2.0 7.8 33.5 3.7 24.3 8.5 3.6 1.7 18.6 9.4 3.4 10.3 2.3 1.6 3.9 1.2 3.5 10.0 4.4 4.8 1.0 12.1 5.4 8.5 2.3 11.1 8.4 2.2 7.3 4.9 5.3 5.9 1.4 4.9 5.9 5.4 14.2 3.2 2.0 0.7 3.2 1.5 7.3 10.6 5.4 11.4 8.6 6.1 12.9 8.8 7.4 12.2 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell line enhanced" "Detected in many" "BJ: 36.5;BJ hTERT+: 55.2;fHDF/TERT166: 45.0;HBF TERT88: 29.0;RPTEC TERT1: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: " "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavourable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.1 1.3 2.1 0.4 0.9 36.5 55.2 23.6 17.0 1.6 1.4 0.1 8.2 45.0 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 11.0 0.1 1.9 6.8 0.7 4.6 6.9 1.8 0.2 0.1 17.5 0.3 0.0 0.5 2.2 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell line enhanced" "Detected in some" "Karpas-707: 5.2;RH-30: 13.2;RPMI-8226: 10.7" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA059704: , HPA059890: " "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favourable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.0 0.2 5.2 0.1 0.8 0.7 0.4 0.6 0.4 0.7 13.2 10.7 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 2.6 0.2 1.0 0.6 2.9 0.1 0.9 0.2 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell line enhanced" "Detected in some" "BEWO: 9.5;HEL: 28.5;K-562: 4.4;SK-BR-3: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in some" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA073447: " "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 1.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell line enriched" "Detected in some" 6 "HEL: 12.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.1 0.6 1.1 1.0 1.2 0.6 0.7 1.5 0.5 0.4 0.5 1.0 1.0 1.6 0.8 1.9 0.2 0.4 0.7 0.2 0.6 12.4 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.5 0.1 0.1 0.3 0.5 0.1 1.3 0.2 0.0 0.9 0.0 0.0 0.8 0.3 1.0 0.6 0.3 0.2 0.5 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.2 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934071-26212536 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.1;testis: 12.5" "Cell line enhanced" "Detected in some" "AF22: 2.3;CAPAN-2: 2.2;HEK 293: 2.6;SCLC-21H: 2.4;U-2 OS: 4.3;U-698: 10.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 5.0;cerebral cortex: 1.9;hypothalamus: 1.3;pons and medulla: 5.4" "Cell type enriched" "Detected in single" 12 "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 12 "B-cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048951, HPA051893" Approved Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA048951: , HPA051893: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.8 0.7 0.4 0.3 5.0 0.5 1.5 0.3 1.9 2.1 0.6 0.1 0.7 0.4 0.3 3.2 0.9 1.1 0.3 0.3 0.5 1.3 0.9 0.2 1.0 0.3 0.2 0.0 0.5 2.1 0.2 8.1 0.2 5.4 0.5 1.1 3.8 0.2 0.6 0.3 2.2 0.6 1.0 0.4 0.3 0.9 12.5 0.8 0.0 1.3 1.4 0.9 0.5 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.0 0.0 1.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.3 1.9 0.5 1.3 0.2 0.0 5.4 0.8 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.0;parathyroid gland: 12.6;retina: 21.6" "Group enriched" "Detected in some" 10 "HDLM-2: 11.0;HEL: 10.1;RT4: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "gdT-cell: 1.4;naive CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.4" "Region enriched" "Detected in single" 5 "basal ganglia: 4.7" "Not detected" "Not detected" HPA045483 Approved "HPA045483: " "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.2 0.2 0.3 0.0 0.3 0.0 0.2 0.2 0.3 0.6 0.2 0.0 4.6 0.0 0.3 20.0 0.3 0.5 0.0 0.3 0.3 0.5 8.5 0.2 0.3 0.5 0.3 0.3 0.4 2.2 12.6 1.0 0.0 0.3 0.3 0.0 21.6 1.4 1.1 0.2 0.5 0.2 0.5 0.2 0.3 0.2 4.2 0.0 0.0 2.2 0.0 0.8 4.4 0.3 0.1 0.3 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.3 0.3 0.0 NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved 3600000 "HPA064055: " "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavourable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavourable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" 8.3 6.3 9.9 9.0 20.1 8.7 4.7 4.7 25.0 6.8 8.5 4.6 5.8 11.4 6.2 4.7 6.1 4.8 5.6 5.0 15.3 5.3 7.2 7.6 7.6 9.1 5.0 9.5 4.2 7.3 7.6 4.9 6.8 6.6 4.9 5.1 4.0 6.0 6.2 6.7 8.5 9.2 5.5 4.4 10.9 12.4 2.7 5.5 4.3 5.1 2.6 5.6 6.0 4.4 9.5 26.5 5.1 20.9 5.1 9.9 9.7 1.5 5.9 1.0 6.4 2.5 3.3 6.7 4.4 7.9 5.8 7.3 4.9 12.3 0.6 5.6 6.0 4.6 2.7 4.9 1.7 7.2 8.3 2.1 3.8 31.8 8.2 5.3 9.3 5.0 5.1 3.8 1.7 9.0 6.8 8.8 3.5 6.7 2.4 14.2 3.1 6.3 6.4 2.4 11.6 3.7 2.3 2.6 3.5 3.5 8.8 9.0 6.0 6.5 6.6 6.4 4.6 14.8 3.3 4.8 3.7 1.4 3.0 8.1 5.3 1.2 20.9 5.1 9.9 18.2 7.9 9.5 9.8 8.8 26.5 8.3 8.1 7.4 0.6 5.1 11.7 6.8 8.7 9.7 9.9 20.1 4.7 25.0 15.3 5.3 5.0 9.5 6.6 5.5 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 23.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB017782, HPA043704" Approved "CAB017782: , HPA043704: " "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favourable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.7 3.2 1.5 8.5 1.5 1.9 7.9 1.3 1.5 5.4 15.6 1.0 5.1 9.3 4.4 13.0 4.8 3.5 5.9 2.9 1.7 1.0 8.6 14.3 6.2 6.6 2.5 1.0 3.3 4.2 1.1 4.6 6.0 3.1 7.4 10.3 4.5 3.6 5.4 2.0 1.6 23.4 2.6 2.3 9.8 4.8 4.1 0.5 10.8 2.6 4.3 6.2 3.1 3.0 6.3 8.1 12.3 7.1 8.6 8.5 3.9 18.8 2.4 2.1 2.8 5.7 5.8 4.6 6.9 7.2 7.7 8.9 3.1 4.0 9.1 5.5 4.4 3.0 3.8 4.5 7.9 8.6 2.0 6.2 2.6 2.4 5.5 2.8 8.6 4.7 5.8 5.2 0.5 6.7 5.4 2.6 8.5 3.4 8.1 8.8 2.1 2.9 4.0 2.1 3.8 8.2 11.0 1.1 1.4 0.3 8.1 4.7 6.7 8.3 6.8 4.6 2.7 7.0 1.1 1.7 3.3 8.0 4.1 6.3 2.1 5.3 6.4 12.3 4.8 7.1 3.5 6.3 5.0 4.8 8.1 5.4 4.8 5.8 11.2 8.6 6.8 4.7 8.5 3.9 1.5 1.5 1.3 1.5 1.7 1.0 2.5 1.0 3.1 0.5 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391245-18401218 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "intestine: 28.4;liver: 75.5" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.8;RT4: 4.1;SCLC-21H: 5.7;SK-BR-3: 3.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043704 Uncertain "HPA043704: " "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.2 0.1 0.2 2.3 0.3 0.0 0.3 0.1 0.2 0.3 14.0 0.1 0.1 13.0 0.4 0.4 0.1 0.2 0.3 0.4 0.1 0.1 0.6 75.5 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.3 5.1 0.1 0.1 0.1 0.1 0.1 28.4 0.4 0.2 0.6 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 1.4 0.0 0.0 0.2 0.3 0.1 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 0.9 0.0 2.8 4.1 5.7 0.1 0.1 3.6 0.0 1.0 0.5 1.5 1.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.1 0.2 0.2 0.3 0.1 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: , HPA070520: " "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 9.8 10.0 15.3 7.3 18.0 8.9 10.5 15.9 17.1 13.7 8.9 13.5 4.9 12.5 13.0 11.5 10.8 10.0 8.3 8.8 20.8 12.2 11.9 8.8 9.4 8.2 10.8 9.9 17.2 10.3 23.9 16.0 10.1 14.2 9.6 10.1 19.9 10.6 13.0 42.5 9.3 10.9 11.6 9.7 9.6 7.6 11.4 10.7 8.5 7.0 12.2 9.3 9.7 10.8 2.5 5.5 14.2 3.5 3.4 4.1 1.8 6.6 4.9 8.7 4.5 9.6 8.8 13.3 3.5 7.1 4.5 4.0 4.6 2.8 4.8 1.5 6.4 1.6 5.2 3.0 4.9 22.8 7.5 17.2 2.0 1.9 6.0 7.9 14.4 14.0 4.6 4.3 3.5 4.5 10.4 8.0 6.8 4.4 7.0 2.8 4.1 3.3 5.5 40.1 2.4 4.9 9.0 8.0 6.3 8.2 5.0 3.6 6.0 4.0 4.9 7.5 5.9 5.1 3.5 9.3 8.0 8.4 4.3 5.0 3.7 11.0 3.5 6.9 3.8 2.7 4.1 1.8 3.4 4.1 2.6 2.5 3.3 4.0 14.2 3.4 2.8 5.5 3.7 1.8 15.3 18.0 15.9 17.1 20.8 12.2 10.8 9.9 14.2 10.7 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109762-70403805 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA060243: " "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favourable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 13.6 13.2 16.9 13.1 14.0 22.5 14.9 19.2 14.0 13.9 17.3 10.1 49.7 12.4 16.6 33.6 20.0 12.5 12.6 15.8 13.9 13.0 16.4 25.5 15.5 16.9 10.8 11.4 18.5 9.7 23.4 17.1 16.2 10.0 14.8 11.8 15.3 14.8 21.7 13.2 14.9 28.8 19.2 9.6 14.5 11.7 15.5 12.9 15.3 13.4 10.3 13.8 18.9 17.2 3.8 2.5 9.4 7.8 2.1 3.8 1.6 8.6 10.8 11.9 6.7 10.8 11.2 12.2 5.0 5.0 3.8 3.7 5.5 10.0 10.2 2.0 9.1 5.1 14.6 6.9 4.3 24.2 11.6 17.9 5.5 8.7 5.7 3.6 4.8 9.7 7.7 5.2 7.5 2.6 5.6 15.7 4.4 8.6 8.9 3.6 6.2 5.1 8.8 5.0 6.4 6.1 14.4 9.1 6.7 8.6 4.6 7.1 10.9 6.6 3.4 5.6 7.1 7.0 2.6 20.7 10.5 10.0 5.7 4.8 8.1 4.5 2.5 3.5 3.8 3.9 2.8 2.2 2.3 3.3 2.5 3.8 2.8 2.7 9.4 2.1 7.8 1.1 3.2 1.6 16.9 14.0 19.2 13.5 13.9 13.0 10.8 11.4 10.0 12.9 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501902-47656877 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavourable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 20.1 8.9 6.6 34.0 7.4 11.1 15.7 11.9 9.9 12.3 10.1 8.1 9.0 6.7 15.5 8.8 16.7 12.0 8.6 11.5 6.7 4.8 9.1 9.3 17.4 25.8 7.9 4.7 13.3 10.7 13.5 13.5 54.7 7.9 9.7 9.0 10.8 13.5 10.0 32.5 15.0 17.1 11.3 9.5 30.8 11.4 9.2 7.2 17.6 13.5 10.5 33.3 15.1 17.7 13.0 6.7 6.0 7.3 2.7 4.0 3.5 5.7 18.8 5.3 7.2 12.5 14.7 37.3 5.6 8.4 9.6 5.1 9.0 6.4 20.1 3.7 9.6 14.2 4.1 6.9 7.3 10.6 2.2 2.7 5.3 12.5 7.4 2.1 15.0 6.7 19.8 9.1 10.6 6.8 6.2 4.7 5.3 62.6 3.2 3.7 1.8 7.2 6.0 3.7 8.6 5.3 13.6 1.0 1.9 14.1 17.6 6.0 8.1 5.5 11.8 5.7 5.0 6.9 2.4 12.9 11.8 20.7 6.6 2.2 3.8 3.4 5.2 4.0 3.5 7.3 3.2 13.0 3.2 3.1 6.7 10.0 3.7 4.0 6.0 2.7 7.0 5.5 4.0 3.5 6.6 7.4 11.9 9.9 6.7 4.8 7.9 4.7 7.9 7.2 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825649 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm Nucleoplasm "HPA004198: AB_1078228, HPA050211: " "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favourable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 13.7 13.4 14.7 12.8 23.0 15.8 17.7 31.9 17.3 14.9 16.9 28.5 17.5 16.4 16.7 16.3 17.1 14.9 14.2 11.8 16.2 11.7 13.6 10.8 13.2 10.8 18.7 12.6 15.5 15.8 35.1 17.7 18.1 14.4 13.1 18.8 14.4 16.4 18.4 17.6 18.4 21.2 19.8 21.8 11.2 14.6 22.6 22.6 16.9 17.7 9.7 13.2 16.6 14.6 2.7 3.1 6.5 2.1 2.1 2.7 1.3 14.0 8.4 19.2 11.5 10.5 11.8 12.5 6.9 8.8 12.5 10.1 21.5 10.0 10.0 7.6 12.3 17.3 17.0 11.6 14.2 5.1 7.6 23.4 9.4 12.6 11.6 13.1 17.3 8.9 21.5 11.6 14.5 11.7 11.9 13.8 10.3 9.2 20.8 8.3 3.9 12.2 14.0 23.1 8.9 9.2 9.5 16.0 10.9 12.6 30.7 11.8 12.9 10.6 11.4 20.3 12.4 15.0 11.4 15.9 13.3 11.6 13.4 7.7 9.0 3.0 1.7 6.5 2.7 1.6 2.6 2.7 2.5 2.3 3.1 2.1 2.3 1.5 4.4 2.1 2.1 2.8 1.4 1.3 14.7 23.0 31.9 17.3 16.2 11.7 18.7 12.6 14.4 22.6 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB072830: , HPA043246: , HPA050288: , HPA051168: " "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favourable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 19.6 21.2 25.4 24.0 30.8 27.0 25.0 41.8 31.5 24.0 30.6 19.6 18.6 33.2 29.0 19.5 25.0 20.5 21.9 17.8 22.4 17.8 25.6 33.8 20.1 19.5 25.1 19.1 25.9 24.3 39.9 39.8 19.8 21.6 20.8 29.7 17.1 20.9 29.1 43.0 23.8 36.9 29.7 26.4 23.7 29.8 22.1 26.4 38.8 25.3 15.7 23.8 29.6 27.0 43.4 29.9 78.2 24.8 30.4 35.5 19.7 23.8 39.9 28.5 23.7 23.5 17.9 14.2 17.6 19.9 19.4 17.6 21.3 10.9 25.1 12.4 30.7 18.3 35.0 21.3 28.8 33.4 25.9 25.0 34.5 25.0 23.0 15.6 29.8 18.3 22.4 30.0 35.2 26.9 21.8 10.4 19.0 15.5 27.5 10.1 14.1 10.9 27.5 28.9 11.7 20.1 27.1 9.7 16.2 29.1 12.7 13.8 12.2 17.9 23.4 20.0 11.8 14.6 24.2 7.2 8.3 14.7 19.0 18.6 17.1 78.2 24.8 52.2 31.3 19.5 25.9 40.7 35.5 34.1 17.5 43.4 34.7 34.8 48.5 30.4 24.0 29.9 31.7 19.7 25.4 30.8 41.8 31.5 22.4 17.8 25.1 19.1 21.6 26.4 NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567589 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm Nucleoplasm "HPA001928: AB_1079454" "unprognostic (9.51e-3)" "unprognostic (7.37e-3)" "unprognostic (4.66e-2)" "unprognostic (2.55e-3)" "unprognostic (2.14e-1)" "unprognostic (7.37e-2)" "unprognostic (3.19e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-3)" "unprognostic (6.42e-3)" "unprognostic (1.96e-1)" "unprognostic (9.86e-2)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.56e-2)" "unprognostic (8.90e-2)" 24.0 22.0 21.3 21.3 19.0 16.8 18.3 33.8 33.5 24.5 17.2 24.3 17.7 16.4 21.3 19.0 15.7 16.3 21.5 18.2 22.0 14.8 16.0 11.2 23.4 11.9 19.0 15.6 28.6 30.0 13.8 39.5 13.2 28.3 21.3 7.6 32.7 29.2 24.5 62.4 22.8 22.2 17.4 12.2 17.4 24.0 10.8 22.0 9.3 16.7 25.0 7.6 16.3 14.7 0.6 1.7 8.1 4.0 0.2 1.9 0.4 19.4 36.7 10.5 10.0 6.1 8.3 31.4 20.2 10.1 11.8 5.3 19.5 14.4 19.8 15.0 16.4 18.5 4.1 21.5 4.8 20.8 8.1 15.9 34.6 11.8 12.3 11.9 20.2 13.3 8.1 14.7 8.8 11.2 20.4 5.9 10.5 16.8 42.9 13.8 14.6 35.8 13.9 17.5 10.0 5.6 22.8 27.7 20.2 24.8 21.0 12.7 17.1 15.1 53.9 27.5 47.6 27.1 42.9 11.3 11.4 12.1 15.6 8.9 25.7 8.1 0.7 1.6 1.9 0.4 0.5 0.6 0.5 1.5 0.3 0.4 0.6 0.5 1.6 0.2 4.0 1.7 0.0 0.4 21.3 19.0 33.8 28.4 22.0 14.8 19.0 15.6 28.3 22.0 NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase" P46934 15 55826922-55993746 "Enzymes, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" 14.1 4.1 2.5 3.1 3.3 4.5 8.7 1.5 2.7 9.9 9.4 2.8 3.4 3.4 10.1 4.1 8.2 3.8 4.5 4.1 2.9 2.4 8.6 21.5 7.2 2.1 3.5 1.3 6.6 2.8 6.5 6.7 20.1 3.5 8.4 3.4 5.4 4.0 6.4 57.7 7.1 15.2 10.9 6.0 5.9 4.4 2.6 3.1 9.4 5.7 9.0 3.3 11.9 8.9 0.1 1.6 1.2 2.8 1.2 2.9 0.9 7.3 11.4 3.1 3.0 4.1 6.8 5.1 14.1 22.3 10.4 10.5 5.1 2.2 1.8 3.7 5.3 12.2 3.4 9.3 17.1 4.1 2.1 9.1 2.7 2.6 21.9 4.0 0.9 11.5 23.0 12.5 21.1 8.5 3.9 0.0 30.5 3.8 5.3 0.0 0.8 1.7 3.9 24.7 1.0 4.3 14.6 0.3 2.0 6.3 4.5 5.6 5.6 3.0 29.6 23.2 7.7 4.9 22.9 1.2 2.6 4.8 15.7 8.5 5.5 0.6 1.0 0.0 1.3 2.8 2.9 0.1 1.5 1.2 0.8 0.0 1.4 1.6 1.2 1.2 1.9 1.6 1.3 0.9 2.5 3.3 1.5 2.7 2.9 2.4 3.5 1.3 3.5 3.1 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" Q96PU5 18 58044367-58401540 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 50.1;SK-MEL-30: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favourable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 5.9 6.8 9.1 5.4 38.8 13.2 15.8 21.4 24.7 5.0 22.6 3.2 18.2 11.1 3.6 6.1 7.0 6.0 7.6 12.7 9.8 7.1 29.9 10.1 26.9 2.5 7.2 14.9 3.0 33.2 9.2 16.5 13.0 4.1 30.6 25.2 12.2 16.5 23.2 38.3 5.9 26.8 8.2 3.2 3.1 26.0 4.6 8.8 0.8 9.1 5.5 5.1 14.9 9.3 1.4 0.4 4.7 0.7 0.9 8.1 0.5 18.4 6.6 3.9 5.8 1.4 0.5 13.6 5.2 23.7 13.4 20.5 7.7 10.0 3.9 16.1 2.0 13.4 5.2 23.1 27.7 9.2 4.6 2.8 4.1 50.1 0.7 0.1 1.7 3.5 15.1 18.1 22.0 1.0 4.8 1.7 5.5 4.5 0.2 0.2 3.4 10.2 3.8 5.3 4.5 13.3 24.1 4.9 1.3 4.3 1.3 39.1 7.9 1.6 7.9 36.2 10.9 2.0 22.3 2.3 3.9 2.4 7.4 2.8 2.9 4.7 0.6 1.7 0.4 0.7 1.0 1.4 1.3 0.3 0.3 0.6 0.8 0.6 0.3 0.9 0.1 0.4 8.1 0.5 9.1 38.8 21.4 24.7 9.8 7.1 7.2 14.9 4.1 8.8 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392857-169612629 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favourable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 9.6 10.5 13.5 9.2 15.8 6.0 8.7 20.7 14.5 13.6 8.4 12.5 7.1 5.4 12.4 9.1 7.9 15.7 10.2 11.4 13.7 13.2 10.2 6.9 7.7 8.0 15.9 11.3 16.3 6.6 15.3 16.5 7.2 16.0 11.6 7.7 8.9 6.4 10.6 7.1 4.7 5.7 11.1 18.2 8.0 8.1 18.3 14.8 14.7 13.3 6.4 7.4 10.0 8.2 4.5 3.3 6.7 3.3 2.2 5.3 1.3 4.2 1.9 7.8 8.4 12.1 13.6 2.5 9.0 8.1 7.2 6.9 2.4 5.1 11.3 1.7 7.8 1.4 7.3 7.6 8.2 12.4 5.0 7.6 7.8 2.9 7.2 7.7 6.1 10.8 4.4 7.3 12.9 7.0 13.5 21.6 9.2 2.7 9.9 3.4 2.5 4.5 6.1 5.1 3.6 7.6 5.0 8.5 9.7 6.5 3.2 6.0 4.0 3.4 8.4 4.6 4.2 4.8 6.0 8.7 13.4 8.7 7.6 3.8 8.0 6.7 2.1 1.8 4.4 3.3 4.8 4.4 3.4 2.7 1.5 4.5 5.1 5.3 1.1 2.2 1.6 3.3 3.2 1.3 13.5 15.8 20.7 12.9 13.7 13.2 15.9 11.3 16.0 14.8 NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm Nucleoplasm "HPA016908: AB_1854364" "unprognostic (9.15e-3)" "prognostic favourable (7.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (4.85e-3)" "unprognostic (2.48e-5)" "unprognostic (5.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "prognostic favourable (5.92e-6)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" 3.9 5.8 9.3 2.7 11.1 0.5 8.7 2.7 7.6 7.3 2.8 11.2 8.4 2.0 6.5 16.0 3.2 26.9 6.0 2.9 9.1 10.0 8.2 1.1 5.5 1.7 7.8 5.4 8.7 2.8 5.0 9.3 4.6 17.3 4.0 3.3 3.0 3.8 6.7 1.7 2.8 2.6 4.3 7.3 1.8 2.3 17.8 5.5 0.2 12.3 2.5 1.7 4.2 3.0 0.9 1.0 1.1 1.3 0.3 2.9 0.3 5.8 2.4 1.7 5.1 6.9 10.4 1.0 2.9 5.4 4.4 3.4 2.2 8.2 0.3 2.1 5.1 3.2 0.5 5.0 6.2 0.5 0.7 0.8 0.4 1.0 2.3 0.6 1.5 4.3 8.4 4.7 2.1 0.9 0.2 0.9 7.4 4.1 0.1 0.5 0.5 2.3 0.0 0.2 0.1 10.1 2.3 2.2 2.4 1.4 0.1 1.9 4.8 0.1 0.9 4.6 2.2 3.6 1.3 1.3 2.3 0.1 3.2 0.2 0.8 0.0 0.3 1.1 0.6 1.3 1.2 0.9 2.9 2.6 0.5 0.6 1.0 0.8 0.9 0.3 0.9 1.0 1.5 0.3 9.3 11.1 2.7 7.6 9.1 10.0 7.8 5.4 17.3 5.5 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0;testis: 41.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.2" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: " "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavourable (9.47e-6)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 1.1 0.7 0.6 6.7 0.5 7.4 1.3 0.3 0.9 0.9 2.5 0.3 0.3 3.4 0.3 1.2 4.2 0.7 1.4 0.9 1.0 0.3 0.6 0.6 1.0 3.9 0.3 0.3 0.6 0.3 0.0 0.3 1.2 0.4 0.9 3.6 0.4 1.0 0.3 0.3 1.8 3.0 0.6 0.6 1.6 1.1 41.0 0.4 14.0 0.3 1.5 4.8 0.6 1.6 1.8 0.9 2.7 0.5 3.9 4.3 0.9 30.3 21.9 16.8 12.0 1.0 1.7 18.5 11.7 11.0 20.7 17.8 11.7 29.8 16.1 5.7 9.0 16.3 14.5 8.8 26.1 24.6 12.1 7.7 19.1 15.7 0.1 15.2 10.5 0.5 1.0 15.9 17.2 13.2 21.1 28.4 20.7 8.4 16.5 10.3 15.9 11.2 16.4 25.7 24.5 7.2 8.7 15.2 16.9 16.9 19.0 14.7 29.2 9.1 6.9 10.3 20.5 20.3 31.4 11.8 21.7 21.3 9.0 11.7 17.1 2.7 0.5 0.4 0.5 0.3 0.2 1.5 0.6 0.3 0.1 1.8 1.1 0.7 2.4 3.9 0.4 0.9 4.3 0.9 0.6 0.5 0.3 0.9 1.0 0.3 0.3 0.3 0.4 0.4 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules Microtubules "HPA019062: , HPA043230: " "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 7.7 2.8 7.1 5.4 12.9 7.1 7.3 3.2 7.1 7.0 13.8 20.4 3.1 7.8 9.1 5.8 3.9 6.0 6.4 5.0 8.7 5.2 6.1 5.7 7.2 4.2 14.0 9.5 7.9 6.4 2.2 3.7 14.8 11.3 5.4 15.0 6.8 5.2 5.0 4.1 5.4 11.7 7.3 9.6 3.9 4.6 14.7 13.3 2.4 5.0 2.7 4.3 6.5 6.0 4.4 7.8 5.9 7.7 2.0 3.5 1.6 0.2 1.4 13.1 7.5 4.2 6.6 0.2 4.2 4.3 5.1 5.7 5.0 7.3 0.0 0.2 5.2 0.9 0.2 3.2 3.1 8.7 6.9 1.0 1.4 13.6 5.4 12.6 6.8 4.8 5.8 2.6 12.2 7.7 1.8 4.4 5.2 3.6 0.6 15.2 12.9 0.3 0.3 1.1 4.7 7.3 1.3 1.3 9.1 1.9 4.0 8.8 1.7 16.2 6.6 0.7 4.3 4.0 4.5 4.7 1.6 8.8 1.1 5.0 7.1 5.9 7.7 5.3 2.1 6.6 1.3 4.4 2.5 1.3 7.8 2.5 1.7 0.6 0.5 2.0 1.5 6.9 3.5 1.6 7.1 12.9 3.2 7.1 8.7 5.2 14.0 9.5 11.3 13.3 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708449-52770949 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol Cytosol "HPA015750: AB_1854367, HPA058543: " "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favourable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 7.2 10.7 15.5 9.1 15.7 7.3 11.0 20.2 16.1 10.6 8.4 10.6 9.6 7.6 10.3 10.7 8.1 15.8 7.5 7.4 12.5 14.2 11.6 12.4 7.7 8.8 12.7 8.6 15.8 10.2 13.4 17.6 8.7 11.9 9.4 9.7 9.1 8.5 11.3 10.8 5.3 6.6 9.5 10.7 7.9 11.0 47.7 12.4 11.1 15.5 5.0 10.4 9.3 10.7 5.1 6.4 12.4 11.8 4.6 5.2 5.5 12.8 10.0 13.7 10.8 12.6 9.1 14.9 9.1 12.3 17.1 17.3 8.7 9.6 13.2 4.3 8.9 6.0 16.7 10.7 23.0 13.1 7.0 10.3 12.2 11.1 7.8 25.1 10.4 5.6 9.9 21.9 14.6 6.4 12.8 10.7 10.7 10.9 13.5 9.2 11.9 9.9 11.9 12.0 9.7 9.6 18.5 10.1 6.1 19.1 11.8 9.0 11.0 15.2 5.8 11.5 11.7 18.3 16.8 12.0 17.5 13.0 13.1 11.9 12.4 12.4 11.8 5.8 4.6 7.3 5.2 3.6 4.0 4.8 6.4 5.1 4.9 4.2 1.8 4.6 4.8 3.2 3.1 5.5 15.5 15.7 20.2 16.1 12.5 14.2 12.7 8.6 11.9 12.4 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129078 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.8;fallopian tube: 12.7;testis: 15.7" "Cell line enhanced" "Detected in some" "T-47d: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035565, HPA041399" Enhanced "HPA035565: AB_10672095, HPA041399: " "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.6 0.3 3.2 1.4 3.2 0.7 0.9 0.4 2.6 0.9 0.4 5.4 0.3 0.5 2.5 3.0 0.4 12.7 0.5 1.3 3.2 1.6 0.9 0.3 4.9 0.5 0.7 1.3 2.8 0.5 0.9 5.3 0.8 11.8 1.5 0.4 0.3 0.5 0.3 0.6 0.5 0.4 0.5 0.9 0.4 0.3 15.7 2.1 0.0 0.7 0.0 0.3 0.4 0.4 0.9 1.1 2.5 0.5 0.6 0.4 0.0 0.5 0.6 0.4 2.2 0.3 1.4 2.8 0.0 0.0 0.0 0.3 0.2 1.4 0.7 0.2 0.0 0.5 0.3 0.5 0.1 0.2 0.4 0.8 0.8 0.5 0.4 1.4 1.7 0.4 1.1 0.2 0.8 0.3 1.5 1.0 0.0 1.7 0.7 1.1 0.6 0.8 0.3 0.2 0.0 2.4 0.6 0.8 1.1 0.5 0.0 1.2 4.2 1.7 0.6 0.2 0.3 0.2 0.3 0.4 0.2 0.4 0.1 0.3 0.4 2.5 0.5 0.1 0.3 0.3 0.4 0.5 0.2 0.2 0.1 0.9 0.3 0.3 0.9 0.6 0.1 1.1 0.2 0.0 3.2 3.2 0.4 2.6 3.2 1.6 0.7 1.3 11.8 2.1 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB045993: AB_2150651, HPA056828: " "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavourable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 14.8 5.3 26.1 22.2 29.1 12.8 18.8 7.2 21.2 20.5 15.6 13.4 4.3 12.5 9.2 7.5 6.8 8.5 18.4 7.0 17.1 16.6 12.9 51.9 17.0 18.1 19.4 13.3 11.2 20.5 1.6 6.4 21.4 14.7 14.8 16.6 18.5 16.9 13.2 5.5 5.1 18.2 23.4 13.0 11.3 19.0 5.8 12.9 4.0 6.3 1.9 22.0 17.7 10.1 21.9 11.5 29.0 18.8 8.3 3.8 7.6 7.7 12.7 12.3 4.8 23.4 30.4 15.3 9.7 15.6 15.1 12.6 12.1 14.5 9.4 15.6 18.8 1.5 6.3 28.3 10.3 10.3 5.6 25.9 10.7 21.1 27.9 4.6 65.0 40.6 4.6 14.3 14.9 16.4 4.6 0.4 27.0 8.1 0.2 5.1 3.1 11.6 10.0 9.2 4.8 16.2 2.8 5.5 1.9 3.2 6.1 13.8 13.1 19.1 32.1 11.1 11.2 7.6 6.6 2.1 2.6 5.4 13.9 10.6 14.7 10.2 18.8 29.0 3.8 12.3 2.4 21.9 2.3 3.2 11.5 9.0 0.4 1.6 23.4 8.3 14.7 10.6 2.8 7.6 26.1 29.1 7.2 21.2 17.1 16.6 19.4 13.3 14.7 12.9 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156963-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 83.7;fHDF/TERT166: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 31.7 31.4 24.9 15.2 23.0 5.6 23.7 7.8 15.6 19.3 20.6 25.5 13.7 11.3 24.5 11.4 18.7 12.8 15.1 74.7 23.9 20.4 16.1 16.0 22.3 14.9 26.8 13.4 17.2 11.1 14.6 17.6 40.5 18.0 20.0 13.2 11.8 13.5 21.3 29.9 10.6 15.8 30.9 34.9 16.4 11.7 9.5 22.6 18.0 14.9 12.8 12.5 27.4 20.7 1.6 2.1 6.1 2.2 3.8 14.7 1.4 7.0 1.8 2.2 0.9 5.9 6.8 2.6 83.7 35.0 34.1 16.2 3.4 7.0 2.5 6.0 113.0 4.3 3.4 4.5 34.5 7.9 4.9 3.4 8.0 1.4 7.1 5.8 7.1 4.2 3.9 22.4 6.7 6.4 2.7 6.3 15.6 2.2 5.0 3.4 1.2 1.4 2.6 5.6 4.4 5.8 3.6 1.4 2.6 13.9 8.0 9.3 5.9 5.3 14.2 9.6 8.1 27.4 8.7 4.4 4.0 1.7 4.2 5.3 7.4 1.9 2.2 3.0 3.2 1.9 14.7 1.3 3.6 4.6 2.1 1.6 2.9 3.6 6.1 3.8 1.7 1.4 6.0 1.4 24.9 23.0 7.8 15.6 23.9 20.4 26.8 13.4 18.0 22.6 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 14.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavourable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favourable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 3.5 4.6 2.9 11.9 4.5 2.0 4.3 1.7 4.9 5.3 4.0 4.7 1.4 4.2 2.1 5.0 4.8 5.9 4.4 1.6 2.9 1.9 10.4 6.9 5.7 7.8 2.3 2.1 4.4 6.4 8.5 9.7 8.7 5.6 5.6 3.2 5.2 5.3 4.1 0.9 4.4 6.5 1.7 3.0 8.4 4.9 4.9 1.4 4.8 10.7 3.5 15.6 4.5 3.0 4.7 14.7 3.2 1.0 1.3 1.1 0.8 2.1 3.5 3.7 2.9 2.0 2.2 11.4 1.0 2.2 1.4 1.8 5.4 5.1 13.2 3.7 2.8 3.9 5.4 4.9 1.4 3.5 6.6 2.9 5.6 10.0 3.5 1.8 3.9 5.1 1.9 2.6 6.1 0.9 4.3 1.3 1.5 4.7 1.8 3.4 3.4 1.1 4.9 2.4 5.8 7.3 5.8 6.7 1.6 3.1 6.5 1.6 9.7 2.4 0.9 1.3 2.4 1.7 1.0 1.5 1.7 8.9 2.1 1.6 3.2 3.2 0.9 1.2 0.8 0.4 0.9 3.0 0.7 0.7 0.1 4.7 0.8 1.1 0.5 1.3 1.0 14.7 0.5 0.8 2.9 4.5 1.7 4.9 2.9 1.9 2.3 2.1 5.6 1.4 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved Approved Mitochondria 190000 Mitochondria "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favourable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 17.0 20.4 12.7 17.7 17.4 7.3 15.1 15.4 13.3 18.6 18.7 18.3 23.5 14.0 25.0 13.8 15.6 20.0 15.9 23.5 11.4 8.7 14.0 13.3 12.9 16.2 20.2 10.6 25.6 15.7 24.7 23.6 14.3 13.0 15.3 8.1 15.4 12.4 18.9 36.2 10.6 15.3 24.7 14.5 14.7 14.8 16.6 18.2 21.5 17.0 14.1 14.4 23.6 18.7 6.0 6.4 7.5 5.4 5.5 6.2 3.1 10.1 12.0 15.2 16.9 19.5 26.8 17.3 16.5 11.6 8.1 7.9 10.1 8.9 17.4 0.1 11.3 14.0 11.6 6.4 9.0 14.2 6.7 8.5 12.0 7.3 12.8 5.1 11.4 18.3 7.6 8.4 6.4 10.1 9.6 11.3 9.7 1.1 10.8 5.2 9.0 6.1 17.5 19.4 9.0 6.1 12.4 7.3 18.7 13.3 6.4 12.7 15.8 14.8 15.2 12.3 5.2 14.3 6.4 18.3 19.5 17.6 9.0 8.7 8.3 7.5 5.4 5.8 4.2 5.0 5.9 2.8 4.8 3.9 6.4 6.0 6.2 5.9 5.5 5.5 3.5 1.8 2.6 3.1 12.7 17.4 15.4 13.3 11.4 8.7 20.2 10.6 13.0 18.2 NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493979-103592552 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 37.1;skeletal muscle: 83.5" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HeLa: 7.6;HMC-1: 6.5;SCLC-21H: 16.2;SiHa: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "intermediate monocyte: 16.0;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 17 "monocytes: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced "HPA044204: AB_10959383" "unprognostic (1.21e-2)" "unprognostic (8.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-4)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (4.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (8.61e-3)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.91e-4)" "unprognostic (3.23e-1)" 1.1 3.9 18.5 3.0 17.5 2.0 1.0 28.2 27.2 6.1 8.6 0.6 1.2 7.7 13.2 11.0 3.6 2.1 2.0 1.1 12.0 7.6 1.3 1.1 1.3 1.3 4.5 18.9 2.1 12.8 2.9 6.5 13.3 6.1 2.8 7.3 7.8 1.5 1.7 83.5 1.9 11.7 11.7 1.2 2.0 4.4 7.5 2.1 0.0 1.2 8.5 1.1 9.2 1.7 0.4 2.1 1.0 37.1 0.2 0.4 1.2 0.8 0.2 1.3 0.0 0.4 0.1 12.9 0.5 0.8 0.2 0.1 0.3 0.3 0.4 0.7 0.1 0.7 0.4 0.2 0.1 0.3 0.7 0.2 7.6 0.6 0.0 0.3 6.5 0.2 0.5 0.1 0.6 0.0 2.1 0.4 0.2 1.1 1.3 0.8 0.0 3.9 0.2 0.6 1.4 0.0 0.5 16.2 5.5 8.1 0.0 0.4 0.7 1.5 0.0 0.1 0.9 0.2 0.2 0.9 0.2 0.3 0.5 0.0 0.3 0.2 1.0 0.2 0.3 16.0 0.4 0.4 0.4 0.4 2.1 0.3 0.4 0.3 1.0 0.2 37.1 1.7 0.1 1.2 18.5 17.5 28.2 27.2 12.0 7.6 4.5 18.9 6.1 2.1 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641266-172691540 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.0;T-47d: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported Vesicles Vesicles "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavourable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 26.6 11.8 7.5 10.3 3.2 1.5 23.9 0.6 7.0 21.4 17.5 5.6 31.2 5.7 26.7 24.7 14.0 15.8 23.0 19.2 10.7 4.2 7.6 4.4 10.5 7.8 3.1 3.2 20.9 4.8 4.1 6.0 5.1 2.7 20.7 11.6 6.1 4.9 28.4 12.3 14.7 12.1 29.1 1.5 0.6 5.9 6.6 2.8 3.6 7.2 13.9 5.4 16.0 30.8 0.0 0.6 0.0 0.2 0.0 0.2 0.0 4.4 2.3 1.2 5.6 0.4 0.2 0.1 5.0 2.2 2.7 3.9 8.5 2.0 0.0 1.4 3.2 1.3 0.5 2.2 1.8 8.1 0.3 6.1 8.1 0.0 0.4 0.0 1.9 0.0 9.7 0.6 2.7 0.4 0.0 1.9 5.7 4.9 1.4 0.1 0.8 0.2 27.0 6.0 0.8 0.1 1.0 1.0 5.8 4.8 7.6 0.2 12.7 0.9 0.8 2.0 11.9 1.4 3.1 0.8 0.2 0.0 5.8 0.1 1.7 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.5 3.2 0.6 7.0 10.7 4.2 3.1 3.2 2.7 2.8 NGLY1 "FLJ11005, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.7 14.4 11.4 19.6 11.4 12.9 15.0 17.1 15.0 9.5 12.4 6.9 11.7 10.5 10.2 13.8 13.2 8.4 10.5 14.3 12.0 9.0 12.8 18.1 13.9 17.4 9.5 12.5 10.6 20.7 9.0 11.3 8.7 11.0 10.9 15.2 7.8 12.4 18.0 46.6 9.0 11.2 8.7 10.1 14.6 11.9 42.0 9.0 18.0 10.3 10.9 18.1 11.5 10.6 26.1 39.7 19.9 10.8 22.6 14.7 10.3 12.2 10.5 5.9 12.4 11.4 10.4 8.4 10.5 8.9 13.3 12.0 6.5 9.3 31.2 12.0 8.9 5.5 19.8 5.5 18.1 14.7 8.4 23.2 8.0 10.5 12.6 21.3 12.7 9.3 7.5 14.6 13.6 14.2 21.9 22.4 13.5 5.3 25.3 12.6 7.9 19.0 25.9 7.7 22.2 12.2 15.1 3.6 4.4 15.3 14.7 9.7 13.9 17.8 9.6 10.5 10.8 12.6 13.5 27.7 23.8 21.7 12.6 23.1 8.2 19.9 10.8 18.9 13.7 10.1 14.7 26.1 13.8 12.6 16.3 21.7 14.0 13.6 12.8 22.6 8.4 39.7 10.4 10.3 11.4 11.4 17.1 15.0 12.0 9.0 9.5 12.5 11.0 9.0 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122687 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 9.0;K-562: 7.6;SCLC-21H: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavourable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favourable (5.30e-4)" 2.5 3.6 5.0 1.8 6.5 2.1 4.6 2.6 8.5 1.9 3.3 7.1 1.7 3.2 2.0 6.1 2.4 3.5 2.7 3.9 5.0 5.1 1.9 9.0 5.1 4.7 5.4 3.9 3.5 12.2 2.4 2.8 1.0 5.2 3.4 3.0 3.3 5.1 2.8 5.2 8.5 4.3 1.8 5.4 2.4 3.0 2.1 3.8 2.4 3.6 0.9 1.8 2.5 1.8 3.3 7.2 0.6 7.2 2.2 2.5 2.6 3.3 2.0 0.8 0.1 1.8 1.7 0.0 3.4 1.1 1.3 0.7 0.1 2.8 0.1 9.0 2.5 4.0 0.0 2.2 1.0 0.1 1.1 0.5 1.0 0.2 2.8 0.0 2.2 2.9 3.3 1.3 1.2 2.8 7.6 0.1 2.8 3.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 1.8 3.6 8.0 0.1 6.8 5.7 2.0 4.1 2.2 0.5 0.2 1.7 2.4 0.0 0.1 0.0 0.1 0.1 0.0 3.4 0.5 6.6 0.6 1.1 7.2 1.2 3.3 1.7 0.8 7.2 2.3 2.5 1.6 0.5 2.2 3.2 0.9 1.8 2.6 5.0 6.5 2.6 8.5 5.0 5.1 5.4 3.9 5.2 3.8 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600614-42648741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: " "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favourable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavourable (6.01e-4)" "prognostic unfavourable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favourable (1.05e-5)" 12.9 14.4 9.8 18.8 22.2 16.3 15.9 42.0 12.3 18.8 10.4 18.5 15.4 11.8 27.2 17.4 11.0 12.0 13.1 11.2 10.9 10.5 9.5 9.7 14.6 15.5 14.5 11.3 22.7 18.4 19.2 26.9 11.1 14.1 12.9 11.1 20.4 13.2 19.5 12.0 20.0 13.3 19.4 15.0 18.5 10.1 17.8 13.8 20.6 14.9 10.9 19.4 12.9 13.9 9.3 8.5 11.7 10.0 11.1 10.2 3.6 8.9 5.1 17.1 7.0 10.2 12.5 9.6 14.5 3.7 6.0 8.2 9.0 7.2 14.1 7.0 4.4 7.9 10.1 3.6 12.4 7.1 8.4 18.1 16.2 14.5 4.4 13.9 11.9 5.1 7.2 11.9 4.5 10.6 18.2 10.9 11.4 3.7 9.5 13.6 14.7 7.5 10.1 7.7 5.8 8.4 6.8 6.0 3.6 15.6 6.5 2.4 9.5 10.1 17.0 10.9 7.9 11.8 14.0 9.5 13.2 9.8 5.8 17.1 6.6 9.2 6.2 11.7 10.2 7.7 9.4 8.9 9.8 8.5 4.7 9.3 10.0 8.7 9.1 11.1 10.0 8.5 8.3 3.6 9.8 22.2 42.0 12.3 10.9 10.5 14.5 11.3 14.1 13.8 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "basophil: 17.6" "Lineage enriched" "Detected in single" 32 "granulocytes: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions" Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: " "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 6.4 30.5 19.4 10.9 14.1 7.4 7.5 7.5 38.2 6.2 6.7 8.3 14.4 8.3 5.7 8.8 4.5 5.1 8.2 8.5 18.2 12.0 13.0 8.2 7.1 11.7 15.2 23.6 4.6 11.5 20.8 9.4 9.1 7.0 6.7 7.1 12.7 5.8 17.4 4.9 4.5 8.3 4.6 15.3 10.1 7.0 17.4 7.5 10.9 13.2 3.7 11.0 7.2 4.4 0.5 0.3 17.6 0.3 0.1 0.5 0.2 4.6 5.4 13.0 4.5 2.8 3.6 5.7 4.6 4.7 7.8 6.0 27.0 4.2 6.3 7.1 3.8 4.4 9.1 8.5 9.0 14.5 5.8 24.7 5.0 4.6 4.7 5.2 25.5 4.7 5.2 5.1 6.1 9.1 9.5 7.6 7.1 5.4 13.3 6.0 5.0 2.7 11.2 8.4 4.6 14.1 5.7 9.5 3.5 7.1 6.8 29.0 10.6 8.3 9.3 5.6 7.5 4.6 9.3 9.0 8.6 6.1 5.4 5.6 6.1 17.6 0.2 0.2 0.3 0.3 0.1 0.5 0.4 0.4 0.2 0.3 0.2 0.5 0.1 0.1 0.3 0.3 0.4 0.2 19.4 14.1 7.5 38.2 18.2 12.0 15.2 23.6 7.0 7.5 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722196-65871725 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.7;intermediate monocyte: 5.9;myeloid DC: 4.1;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;monocytes: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria 53000 Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavourable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favourable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 4.5 2.4 7.6 4.7 10.5 2.9 7.3 2.8 11.9 4.1 6.8 5.8 1.0 2.4 5.8 5.0 5.2 3.3 2.7 5.1 7.2 7.6 7.5 18.9 3.4 5.1 8.7 8.5 4.0 11.0 3.6 2.4 4.9 9.8 5.4 6.5 2.0 4.3 2.6 15.0 5.7 5.3 5.5 10.9 5.8 7.5 2.4 6.2 1.8 5.5 7.9 4.0 4.3 3.3 0.9 4.1 0.6 5.9 0.9 0.7 1.8 9.2 8.9 5.3 8.7 6.6 11.4 10.6 9.3 3.9 5.5 6.0 5.0 5.5 13.2 11.8 11.2 7.4 6.8 14.4 9.6 3.9 4.6 3.6 6.6 12.8 5.7 8.3 2.2 8.7 7.9 7.6 9.1 15.5 7.8 2.8 11.8 7.1 5.7 7.5 16.1 2.5 6.7 11.2 20.8 9.0 4.1 16.3 8.5 7.5 7.8 7.7 9.3 9.9 8.9 3.7 4.4 5.3 7.0 2.4 4.8 5.8 5.6 16.3 5.5 0.2 4.7 0.2 0.2 5.9 0.3 0.9 0.4 0.3 4.1 0.9 0.7 0.5 0.6 0.9 4.1 0.2 0.1 1.8 7.6 10.5 2.8 11.9 7.2 7.6 8.7 8.5 9.8 6.2 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 45051610-45109016 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.8 32.6 44.9 28.2 37.3 12.0 26.1 34.5 64.3 23.7 24.4 17.2 22.9 23.4 27.3 29.3 26.6 30.9 17.3 26.8 37.7 29.6 28.8 36.6 26.7 27.2 27.7 43.6 29.3 21.8 41.6 23.7 32.7 38.1 23.7 23.1 18.1 34.9 30.1 75.5 28.8 24.8 30.1 36.6 28.2 23.4 26.1 34.0 20.7 29.4 18.6 30.9 25.1 43.3 10.2 18.2 7.6 9.3 7.4 10.0 3.3 16.9 22.4 19.4 17.1 35.1 22.7 20.4 18.9 25.0 36.8 30.4 25.0 14.6 20.4 27.4 26.0 16.0 33.3 26.5 34.2 51.8 23.2 20.3 15.0 24.7 23.1 26.1 24.5 28.6 24.1 27.4 21.8 24.7 32.2 10.4 20.5 14.5 31.7 17.8 18.1 23.5 21.7 28.9 15.5 29.1 15.7 16.2 14.6 11.9 10.9 17.1 23.6 20.7 19.8 22.5 17.3 18.1 25.1 16.1 22.8 20.4 24.1 14.7 23.8 6.5 8.1 7.6 7.9 9.3 7.2 10.2 7.8 9.3 6.6 7.6 10.0 7.6 5.3 7.4 6.9 18.2 7.5 3.3 44.9 37.3 34.5 64.3 37.7 29.6 27.7 43.6 38.1 34.0 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 33.5;HMC-1: 28.0;TIME: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 8.7;eosinophil: 7.9;gdT-cell: 7.2;MAIT T-cell: 12.9;memory CD4 T-cell: 11.5;memory CD8 T-cell: 8.3;naive CD4 T-cell: 14.7;naive CD8 T-cell: 9.3;NK-cell: 12.9;T-reg: 17.5" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;NK-cells: 12.9;T-cells: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 29.3 5.4 18.9 6.5 17.3 3.8 19.2 35.6 25.3 12.0 9.9 6.0 4.7 7.4 14.5 5.0 8.2 8.9 8.1 9.6 12.8 9.2 10.8 18.5 7.2 9.0 8.8 15.0 18.2 7.1 28.5 7.9 5.1 10.3 10.7 10.7 8.3 5.8 9.4 18.8 11.5 11.9 12.5 10.3 10.1 8.8 14.5 9.9 23.7 6.9 4.5 8.9 10.1 20.1 1.9 0.3 8.7 0.5 12.9 17.5 3.9 2.7 3.6 4.1 3.1 11.4 12.3 0.8 6.1 5.0 5.6 7.7 3.5 12.6 0.1 4.3 33.5 3.5 3.7 3.4 9.6 3.7 4.8 7.5 1.7 4.7 7.6 0.5 28.0 10.9 3.6 8.0 2.4 21.8 3.5 0.5 21.0 3.4 5.7 1.4 3.0 3.5 4.3 6.1 0.5 4.2 0.6 1.2 4.8 7.4 1.2 2.0 3.8 2.3 48.6 5.6 8.3 24.8 4.4 4.3 4.5 0.3 6.9 2.0 4.1 8.7 0.3 7.9 7.2 0.4 12.9 1.4 11.5 8.3 0.3 1.9 14.7 9.3 1.2 12.9 0.5 0.2 17.5 3.9 18.9 17.3 35.6 25.3 12.8 9.2 8.8 15.0 10.3 9.9 NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554535 "Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" Nucleoli "Intermediate filaments" "HPA036347: " "unprognostic (3.03e-1)" "unprognostic (4.93e-2)" "unprognostic (4.99e-2)" "unprognostic (3.14e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "prognostic unfavourable (3.69e-5)" "unprognostic (2.48e-1)" "unprognostic (1.31e-1)" "unprognostic (8.90e-2)" "unprognostic (1.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.80e-2)" "unprognostic (3.32e-2)" "unprognostic (3.40e-1)" "unprognostic (3.54e-2)" "unprognostic (4.65e-2)" 12.7 11.3 10.4 10.3 15.1 19.3 11.0 16.4 19.3 14.7 11.2 14.1 6.8 7.7 13.3 11.6 12.1 11.4 8.8 8.3 10.8 9.7 9.6 15.2 9.4 14.4 8.6 9.6 16.8 14.7 15.5 10.5 9.8 12.0 13.0 10.0 9.4 9.1 10.3 17.9 18.0 11.4 12.4 7.2 22.0 11.0 9.4 9.2 20.9 9.4 8.9 14.9 11.0 9.3 6.9 5.8 5.0 4.8 2.8 8.4 1.9 5.1 7.3 4.1 12.4 5.5 3.3 4.5 5.0 3.3 5.3 5.6 10.0 7.0 14.2 6.1 5.6 6.8 8.3 6.9 9.1 5.7 4.5 9.6 11.3 7.8 5.6 8.1 5.3 4.9 2.1 11.2 9.8 6.2 11.2 6.0 5.4 8.8 7.9 7.3 5.6 7.1 10.1 9.7 6.6 4.1 4.7 8.0 3.7 7.8 9.9 6.2 6.4 3.7 8.0 8.4 6.9 5.9 8.4 5.0 4.7 25.9 7.8 9.1 3.9 5.0 3.5 2.6 5.7 3.2 5.7 5.1 8.1 5.2 2.3 6.9 8.4 7.0 2.2 2.8 4.8 5.8 5.1 1.9 10.4 15.1 16.4 19.3 10.8 9.7 8.6 9.6 12.0 9.2 NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726951 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 142.1" "Cell line enhanced" "Detected in many" "A549: 162.9;Hep G2: 143.8;SiHa: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Enhanced Cytosol 310000 Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" 31.3 24.2 12.8 6.4 20.7 0.6 77.1 2.7 9.1 7.6 23.2 7.8 5.7 29.5 3.9 8.6 36.3 8.2 77.2 9.3 9.9 7.5 44.7 1.2 17.2 6.9 11.3 6.0 3.7 2.5 7.0 3.7 3.5 25.5 9.8 20.8 20.2 10.5 7.6 7.6 2.3 17.7 22.7 10.4 6.0 142.1 3.8 4.9 0.1 25.7 69.7 16.2 21.2 18.9 5.2 3.2 0.9 3.2 15.1 12.3 4.4 14.3 162.9 13.7 61.0 34.1 49.4 5.1 24.3 43.7 25.1 38.8 19.8 93.0 0.4 28.9 125.7 15.0 5.3 27.4 12.9 5.8 0.2 0.7 40.4 143.8 45.2 3.4 11.7 11.6 17.4 43.5 5.0 62.2 5.9 1.0 134.1 46.5 0.6 6.3 7.2 15.9 1.1 2.9 6.6 50.0 52.2 4.9 1.1 185.1 26.3 108.3 42.5 11.4 42.1 25.3 10.5 9.4 19.1 0.8 3.2 0.6 32.4 1.8 125.1 0.6 3.2 0.2 5.7 0.3 2.9 5.2 6.6 7.2 3.2 2.1 2.1 4.7 0.9 15.1 0.3 1.2 12.3 4.4 12.8 20.7 2.7 9.1 9.9 7.5 11.3 6.0 25.5 4.9 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3028869 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 62.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol 6500000 Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavourable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 24.7 45.6 18.2 11.0 17.6 27.2 21.9 44.3 28.1 12.9 11.5 8.9 8.8 15.6 10.4 15.4 12.1 11.2 12.8 38.2 16.0 13.3 82.9 47.0 11.7 17.5 17.0 23.5 13.5 18.4 12.1 9.3 12.1 24.5 12.7 9.0 18.0 24.5 13.5 41.3 20.2 15.5 10.7 11.8 15.3 12.8 7.7 12.5 7.0 11.9 13.9 7.9 10.4 11.0 3.2 16.6 62.1 25.2 7.3 9.3 13.1 12.6 21.4 13.0 28.7 23.1 13.7 14.0 12.3 15.8 11.3 12.8 22.5 4.8 11.1 44.9 21.1 9.7 13.4 8.5 8.9 25.8 11.4 6.8 26.3 22.5 18.8 6.8 21.8 8.4 10.2 13.8 12.8 11.0 38.9 6.6 9.4 28.1 7.8 12.7 17.7 17.8 14.6 15.6 32.4 17.1 6.8 2.8 5.1 18.6 8.0 39.0 10.9 4.7 19.0 10.7 4.2 14.3 5.3 14.5 32.8 3.4 12.6 20.8 21.1 5.6 25.2 13.5 9.2 15.7 6.6 3.2 8.3 8.3 16.6 2.1 5.0 5.7 62.1 7.3 13.9 1.7 9.3 13.1 18.2 17.6 44.3 28.1 16.0 13.3 17.0 23.5 24.5 12.5 NR1D1 "ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092787-40100725 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 16.3" "Group enriched" "Detected in many" 6 "monocytes: 4.2;T-cells: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavourable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favourable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 19.4 15.1 12.2 7.6 14.7 6.0 30.5 30.7 32.5 45.9 13.9 6.4 17.3 15.2 16.5 6.1 16.8 10.7 8.2 43.7 8.8 5.2 9.8 14.8 12.7 8.8 4.7 11.7 33.3 8.3 4.8 10.9 7.3 6.1 15.5 5.5 28.0 53.0 18.6 51.2 79.3 8.8 27.3 6.0 7.8 7.9 7.3 6.8 1.8 13.9 11.7 10.6 28.0 25.4 1.8 1.1 0.1 4.2 0.8 16.3 1.5 2.8 4.1 0.8 3.3 4.9 3.4 1.2 6.3 10.3 2.1 2.6 2.7 10.3 3.4 3.8 7.2 8.1 2.2 9.4 1.5 2.9 2.3 2.5 4.1 6.9 8.0 3.7 3.7 7.4 6.8 7.1 15.2 2.6 3.7 32.2 2.0 2.0 5.5 3.3 1.6 6.5 3.9 1.3 10.6 2.8 2.6 2.8 1.6 3.9 5.2 6.4 2.5 3.1 2.5 9.3 9.2 7.6 4.9 11.7 17.8 1.4 12.6 2.1 7.1 0.0 0.4 0.0 3.9 1.6 16.3 1.5 4.9 5.7 0.9 1.8 4.5 3.2 0.1 0.8 4.2 1.1 6.5 1.5 12.2 14.7 30.7 32.5 8.8 5.2 4.7 11.7 6.1 6.8 NRF1 "ALPHA-PAL, EWG" ENSG00000106459 "Nuclear respiratory factor 1" Q16656 7 129611714-129757082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029329 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029329: AB_10601240" "unprognostic (2.80e-2)" "unprognostic (2.20e-3)" "unprognostic (4.51e-1)" "unprognostic (4.04e-2)" "unprognostic (2.01e-1)" "unprognostic (4.20e-3)" "prognostic unfavourable (6.02e-4)" "unprognostic (1.09e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (1.83e-2)" "unprognostic (2.06e-1)" "unprognostic (6.52e-2)" "unprognostic (4.20e-1)" "unprognostic (2.06e-3)" 14.8 7.3 10.9 18.9 13.0 20.3 18.2 22.2 11.1 15.4 10.3 12.6 16.0 9.0 15.7 10.4 10.1 18.7 10.0 12.3 11.5 11.1 10.0 7.8 11.2 18.7 12.1 7.7 24.4 15.2 13.5 10.9 12.5 11.5 11.5 9.9 11.7 13.8 13.9 19.3 12.2 10.7 14.0 9.6 14.2 8.7 17.2 15.2 29.2 13.8 11.4 16.1 12.8 19.2 8.8 7.0 13.1 7.0 5.8 13.3 6.2 11.6 9.6 13.8 12.2 8.4 6.7 11.0 8.1 8.5 12.5 9.8 11.6 7.8 13.4 6.0 9.2 8.9 14.9 8.2 12.8 12.8 10.6 11.1 8.1 7.8 6.1 13.5 11.1 5.7 7.8 12.3 11.9 9.2 13.4 10.4 7.6 10.6 26.5 12.8 12.9 8.5 17.0 11.2 11.9 7.1 8.5 12.0 13.1 12.3 12.8 8.2 7.9 13.0 7.0 7.1 9.8 8.2 14.9 11.3 11.2 23.8 7.5 12.6 13.6 6.1 5.5 13.1 11.4 6.9 13.3 7.7 8.7 10.5 7.0 8.8 9.6 8.2 11.4 5.8 7.0 4.7 9.1 6.2 10.9 13.0 22.2 11.1 11.5 11.1 12.1 7.7 11.5 15.2 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell line enhanced" "Detected in many" "AF22: 23.0;EFO-21: 23.0;Karpas-707: 16.8;RH-30: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: " "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavourable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 3.4 23.0 0.2 9.2 1.0 10.6 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.0 10.3 4.8 4.8 4.6 2.0 0.0 1.3 0.0 3.6 1.8 1.9 0.0 0.0 4.7 3.1 2.5 0.8 8.3 0.0 16.8 3.1 0.5 0.1 0.2 4.5 1.4 0.0 33.0 4.0 2.5 5.9 2.7 0.1 2.6 0.7 0.2 1.2 0.1 6.2 3.8 12.8 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell line enhanced" "Detected in many" "BEWO: 24.3;CACO-2: 12.9;RPMI-8226: 18.7;RPTEC TERT1: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favourable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.2 12.3 7.5 0.3 0.2 0.3 24.3 2.9 3.0 8.1 3.3 12.9 0.4 3.7 1.8 0.8 4.5 1.7 4.4 3.5 0.0 0.2 0.0 0.7 2.2 5.2 0.0 0.0 1.4 3.3 4.7 2.8 0.3 0.5 0.9 1.5 0.5 0.0 0.0 4.8 0.4 0.0 0.5 18.7 22.2 0.0 1.1 0.1 0.8 3.5 0.3 3.6 0.0 0.9 2.9 1.4 0.3 4.6 6.6 1.0 2.3 0.4 0.0 1.1 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 28.8;seminal vesicle: 36.3;testis: 27.2" "Cell line enhanced" "Detected in some" "AF22: 6.1;HAP1: 11.4;HEK 293: 8.4;NTERA-2: 20.9;SH-SY5Y: 4.6;U-2 OS: 10.5" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.1" "Low lineage specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 1.0 2.3 9.3 1.4 10.7 1.8 1.4 6.0 13.1 4.4 2.0 0.9 28.8 1.1 5.5 18.3 1.7 3.4 2.0 0.9 4.9 13.6 3.1 1.9 0.7 0.9 5.3 8.0 19.2 0.6 0.5 4.5 0.5 6.2 17.9 1.3 0.8 1.0 36.3 0.5 1.0 1.2 4.9 1.9 3.1 1.1 27.2 1.2 0.0 0.8 0.0 0.9 2.8 2.9 0.8 0.1 0.0 0.7 2.1 1.0 0.3 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 11.4 0.5 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.8 1.0 0.0 0.1 0.3 0.0 0.6 0.0 2.1 0.5 0.0 0.0 0.3 9.3 10.7 6.0 11.7 4.9 13.6 5.3 8.0 6.2 1.2 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496596 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;testis: 35.5" "Cell line enhanced" "Detected in many" "HAP1: 33.1;NTERA-2: 20.6" "Cancer enhanced" "Detected in many" "testis cancer: 17.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.7;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD8 T-cell: 3.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 3.7" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.2 5.4 11.2 1.4 21.9 1.6 2.8 7.4 26.1 3.8 2.6 0.8 4.4 1.7 5.9 4.3 1.9 1.6 2.2 0.8 7.0 17.9 0.9 0.6 0.8 1.1 5.3 12.7 10.0 3.8 0.5 2.8 0.6 5.3 10.1 1.4 0.5 1.3 11.9 0.6 1.7 1.5 5.0 1.8 0.9 0.9 35.5 1.1 3.6 1.0 0.2 1.1 1.7 1.6 0.5 0.4 0.0 0.2 1.9 3.7 1.0 0.0 0.5 10.0 0.0 8.6 11.0 0.0 4.6 1.3 0.2 0.2 0.0 0.0 0.0 0.2 5.6 0.7 33.1 11.3 0.1 0.0 2.2 0.0 0.0 0.0 4.1 0.0 2.2 6.7 4.5 3.0 11.0 7.8 0.0 0.0 9.3 0.2 12.5 0.0 20.6 8.4 0.0 7.0 0.0 2.0 0.0 0.0 6.5 2.0 0.0 1.8 0.0 0.0 4.5 2.3 10.9 0.6 0.0 4.3 2.0 7.0 1.5 0.0 0.9 0.0 0.0 0.0 3.7 0.0 1.4 0.5 1.2 1.9 0.4 0.3 0.2 3.1 0.0 1.9 0.2 0.2 0.0 1.0 11.2 21.9 7.4 14.9 7.0 17.9 5.3 12.7 5.3 1.1 NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343713 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB004684: AB_425306, HPA044903: , HPA058623: , HPA067639: " "unprognostic (2.74e-3)" "unprognostic (2.58e-2)" "unprognostic (3.37e-1)" "unprognostic (2.05e-3)" "unprognostic (3.08e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (6.55e-2)" "unprognostic (7.06e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (2.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" 12.0 18.0 21.6 9.6 21.9 10.2 20.6 14.0 25.5 14.9 14.9 26.0 15.4 12.8 15.7 30.2 14.5 20.5 12.3 16.0 17.3 18.6 10.7 17.5 11.2 12.2 19.5 19.0 28.3 20.9 12.0 19.0 14.1 20.5 16.5 15.3 15.7 16.1 13.0 30.8 13.9 10.1 14.7 20.7 11.3 13.0 8.6 19.1 18.6 3.8 13.2 13.8 14.4 12.1 16.6 15.8 14.3 12.2 14.3 22.2 11.2 23.6 9.8 12.7 4.5 8.8 16.2 9.2 11.4 25.9 13.3 13.9 6.7 11.2 6.6 9.5 14.2 10.4 11.5 28.2 13.5 24.6 10.3 14.2 18.4 12.5 25.4 10.9 5.8 16.3 18.2 17.1 32.2 27.3 4.0 26.9 19.3 14.7 11.3 10.3 7.8 28.1 14.7 7.9 16.6 13.0 7.7 2.6 10.4 18.5 7.0 10.7 5.7 11.8 17.6 11.5 10.3 7.5 11.9 6.1 9.8 11.6 14.3 10.5 14.2 14.3 12.2 9.7 11.7 10.3 16.7 16.6 19.2 15.2 15.8 15.0 22.2 19.6 4.5 14.3 10.7 14.7 19.7 11.2 21.6 21.9 14.0 25.5 17.3 18.6 19.5 19.0 20.5 19.1 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392674 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol 110000 Cytosol "HPA047027: , HPA055953: " "unprognostic (2.42e-1)" "prognostic favourable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 10.5 11.4 38.8 9.3 28.6 8.8 12.6 33.4 40.0 15.4 11.4 16.8 10.3 7.7 11.4 25.9 10.8 15.2 8.5 16.9 33.8 30.0 15.3 10.1 11.2 10.5 29.4 25.6 17.4 9.1 27.9 9.3 8.9 26.1 11.4 9.7 11.2 9.4 15.6 50.7 11.2 8.0 11.2 20.3 13.0 8.4 7.3 21.3 5.4 21.3 8.7 12.1 8.6 9.9 4.5 6.4 12.4 5.9 2.1 3.9 2.6 5.4 4.0 10.7 21.0 7.2 12.2 4.7 3.9 6.7 4.1 3.0 4.8 3.8 19.5 5.4 7.1 4.6 6.1 10.7 7.7 7.2 7.7 21.5 5.6 10.3 7.1 20.2 11.2 10.9 10.0 5.0 9.4 11.8 21.3 7.1 6.6 5.7 14.0 23.7 6.9 4.0 12.2 8.9 20.3 9.4 11.4 15.2 16.9 8.8 12.5 15.9 12.5 14.5 12.9 8.3 3.0 7.2 8.6 6.1 14.0 14.3 5.0 20.7 12.9 1.9 5.8 12.4 3.4 5.9 3.9 3.4 3.4 3.2 6.4 4.5 3.2 3.7 4.1 2.1 5.8 3.2 2.4 2.6 38.8 28.6 33.4 40.0 33.8 30.0 29.4 25.6 26.1 21.3 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA017593: AB_1854703, HPA047027: , HPA057684: " "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favourable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 17.2 29.7 14.1 14.7 9.5 37.4 20.4 7.0 29.0 15.2 14.7 6.7 17.5 6.5 13.6 24.8 13.7 12.8 40.0 140.7 12.4 12.4 47.9 11.2 11.3 10.9 9.4 13.7 41.9 21.1 16.1 11.9 19.2 13.9 27.1 16.9 25.1 65.2 14.8 40.3 8.1 12.7 13.8 12.6 9.2 13.1 10.6 6.3 14.6 25.5 22.4 8.9 19.6 32.9 6.0 4.1 13.6 3.6 7.6 6.6 2.5 5.8 5.1 9.2 10.3 34.3 14.2 11.6 16.4 13.1 9.4 7.0 47.4 14.7 8.2 3.6 13.1 7.4 25.8 8.3 14.5 12.6 5.4 30.9 4.4 24.1 33.1 16.1 7.5 30.8 27.8 9.7 21.8 53.6 31.4 11.6 10.8 6.0 14.9 15.4 14.5 12.1 12.6 8.2 8.9 11.4 42.7 7.4 9.6 13.3 26.2 36.9 19.0 21.0 20.3 8.1 4.7 12.1 10.4 6.5 8.1 12.2 4.2 12.7 24.7 8.2 2.8 13.6 3.9 3.6 6.6 6.0 5.8 3.9 2.6 4.7 6.2 5.8 2.4 7.6 2.9 4.1 5.2 2.5 14.1 9.5 7.0 29.0 12.4 12.4 9.4 13.7 13.9 6.3 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like 1" O75147 2 219550729-219571859 "Disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 82.2" "Cell line enhanced" "Detected in many" "BEWO: 45.2;SK-BR-3: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.8;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 10 "dendritic cells: 2.7;granulocytes: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome Centrosome "HPA036404: AB_10670437, HPA036405: " "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavourable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 10.7 26.9 13.4 7.0 11.5 1.2 11.7 18.0 16.2 17.6 8.7 10.3 10.5 3.8 18.2 23.3 7.3 19.9 14.5 30.7 12.8 8.2 19.6 14.5 9.3 3.4 5.5 10.9 82.2 35.6 23.5 16.6 19.3 11.5 15.1 2.3 19.1 25.5 19.1 21.0 14.8 4.8 10.5 8.8 8.2 10.3 15.5 11.5 0.8 34.1 12.4 2.6 10.1 12.1 0.1 2.7 6.8 0.4 0.1 0.2 0.0 9.5 6.5 11.9 24.8 8.3 6.1 45.2 7.2 10.6 9.2 8.6 5.6 15.0 0.0 15.3 9.8 9.8 9.2 5.4 1.9 0.0 16.1 20.8 6.2 28.4 6.2 0.5 0.1 16.5 4.5 2.1 3.5 1.0 8.5 0.2 6.5 23.7 0.0 5.9 28.3 6.7 10.6 10.5 0.0 16.7 9.1 5.2 17.9 8.2 43.9 16.5 4.0 18.0 2.4 9.8 10.6 3.1 2.8 0.0 0.0 0.0 5.7 0.0 9.7 6.8 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.8 0.1 0.4 2.7 0.0 0.0 13.4 11.5 18.0 16.2 12.8 8.2 5.5 10.9 11.5 11.5 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922028-48958386 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/70: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favourable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favourable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favourable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 23.5 27.5 32.4 26.8 40.9 38.4 21.9 35.0 52.4 21.3 22.9 28.2 23.4 30.5 25.5 26.8 20.5 25.1 20.9 16.6 29.8 31.3 22.6 24.5 25.2 30.8 25.4 29.8 30.0 25.4 29.6 26.8 23.1 29.4 24.0 17.8 20.4 26.9 27.4 24.4 24.5 29.1 27.1 21.4 34.5 22.3 12.7 24.0 34.8 24.5 14.4 27.2 22.1 22.7 7.8 6.3 8.6 5.1 18.6 7.5 3.5 6.1 9.3 4.3 10.7 7.4 6.6 5.0 5.4 6.3 6.8 7.4 4.6 6.8 6.9 3.5 6.8 7.5 6.5 5.4 6.4 8.0 7.9 5.2 9.4 5.3 6.2 4.9 5.8 7.3 5.1 7.1 4.8 5.4 6.5 10.9 4.8 6.1 7.7 10.7 7.8 7.3 6.1 6.4 8.9 4.8 5.5 4.2 7.4 7.1 4.6 7.1 6.1 4.5 7.6 4.4 5.6 11.7 4.4 182.8 45.6 6.6 6.9 6.9 3.0 5.2 3.4 7.0 7.0 5.1 5.8 7.8 5.5 6.0 4.8 6.0 5.2 7.5 8.6 18.6 4.7 6.3 7.0 3.5 32.4 40.9 35.0 52.4 29.8 31.3 25.4 29.8 29.4 24.0 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive 1" O95747 3 38165089-38255488 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol 21000000 Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 17.6 16.8 9.4 18.3 13.4 24.2 15.9 17.4 14.9 16.8 15.4 9.2 35.7 12.4 14.9 14.7 31.6 11.6 18.9 15.5 11.9 9.0 18.3 17.6 14.6 13.9 13.6 9.3 16.7 12.3 23.7 15.3 21.4 12.3 16.5 16.8 13.0 15.1 23.9 32.6 17.4 21.4 17.0 12.9 15.8 14.0 11.2 13.2 26.2 14.2 24.1 19.6 23.5 19.2 2.3 4.4 10.1 4.8 5.0 4.7 1.6 17.5 8.0 16.1 11.2 11.2 13.0 18.3 15.6 21.4 22.5 24.5 10.3 11.5 19.5 7.9 18.6 10.9 21.6 16.0 29.8 20.6 8.8 21.3 17.1 11.3 13.5 13.1 13.0 10.3 18.9 20.8 33.7 14.0 16.1 11.2 38.5 4.9 25.3 9.5 16.9 9.6 8.8 13.5 15.0 13.9 13.4 8.4 12.9 17.0 43.2 10.6 14.2 8.6 12.7 14.2 14.1 21.5 23.0 8.6 10.2 14.3 19.4 16.4 28.2 10.1 2.8 6.1 3.3 4.8 3.5 1.9 4.0 3.1 4.4 2.3 3.0 3.7 5.5 5.0 4.1 2.5 4.7 1.6 9.4 13.4 17.4 14.9 11.9 9.0 13.6 9.3 12.3 13.2 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860694 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 383.4;pancreas: 677.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" 140000000 "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavourable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 18.0 34.7 6.3 15.4 8.4 35.0 16.1 6.1 6.5 22.1 40.5 9.0 45.0 42.6 14.7 29.1 40.3 12.8 42.3 20.7 6.3 5.9 27.2 383.4 20.9 29.1 7.9 4.5 14.3 677.5 6.4 23.4 58.5 7.2 22.5 8.5 12.3 251.9 42.5 31.0 24.3 112.8 11.0 5.2 36.7 31.6 9.1 7.2 10.5 29.7 50.7 46.4 16.5 20.5 21.6 71.3 45.8 60.8 38.8 55.9 70.8 57.7 50.3 18.6 60.0 50.4 59.3 44.2 112.8 72.8 49.2 66.6 36.9 50.6 23.3 49.6 72.5 41.0 20.5 44.1 28.5 15.0 34.7 34.9 52.9 150.1 66.3 110.1 57.7 44.7 30.0 39.3 41.7 81.0 24.7 100.7 35.0 52.7 31.5 87.5 14.6 45.8 25.8 33.3 46.2 38.2 69.8 22.4 24.8 56.2 162.4 58.5 73.4 129.7 62.9 92.4 46.3 52.4 55.0 72.4 52.4 22.0 121.4 42.4 70.4 45.8 60.8 38.3 53.5 38.7 55.9 21.6 36.4 42.8 43.4 18.7 21.2 31.5 20.0 38.8 27.6 71.3 25.7 70.8 6.3 8.4 6.1 6.5 6.3 5.9 7.9 4.5 7.2 7.2 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell line enhanced" "Detected in many" "U-266/70: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.8 8.0 17.4 7.8 7.1 11.9 13.9 13.6 9.7 12.9 15.2 11.4 15.9 10.6 5.0 11.7 6.1 12.1 14.4 20.4 12.2 9.8 11.2 5.4 0.7 4.7 18.9 16.6 8.8 8.7 15.1 22.5 3.0 7.4 18.7 23.4 0.8 12.0 8.7 25.7 6.9 18.5 22.5 0.4 3.3 9.9 7.5 7.4 7.3 3.1 5.7 13.9 8.6 0.2 8.6 14.9 45.9 11.3 51.4 26.4 7.0 7.2 12.6 9.3 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles 590000 "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.36e-4)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 28.7 18.9 22.4 27.6 23.5 21.4 56.5 17.4 20.7 19.5 23.0 27.8 17.4 19.0 22.6 19.2 23.4 17.9 20.7 29.0 22.6 22.0 19.5 34.3 35.7 50.2 26.8 13.5 19.9 16.6 30.5 13.0 27.6 22.8 17.7 23.0 12.9 19.6 21.2 34.2 16.3 25.2 23.0 32.1 34.6 18.4 15.9 24.8 44.9 16.9 19.1 31.9 24.1 32.7 6.6 13.7 25.9 12.6 6.6 10.8 7.0 35.2 12.6 17.8 13.0 12.6 16.7 26.4 17.9 14.8 19.5 17.8 29.9 18.1 22.6 51.2 18.1 18.1 18.8 17.0 30.2 10.1 9.1 33.5 14.5 23.5 25.6 32.5 32.2 13.3 14.0 17.4 37.1 19.2 16.1 28.2 18.9 37.2 30.9 16.8 10.6 19.0 28.3 10.1 20.5 17.0 24.8 10.4 11.8 23.9 16.9 13.5 59.3 23.6 19.8 16.2 9.0 16.9 26.3 19.2 33.9 55.7 13.4 32.6 15.3 16.5 10.3 24.5 6.3 12.6 8.5 6.4 7.3 7.1 13.7 6.6 5.4 6.3 25.9 6.6 10.8 5.1 10.8 7.0 22.4 23.5 17.4 20.7 22.6 22.0 26.8 13.5 22.8 24.8 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;pancreas: 46.5;pituitary gland: 37.2" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HAP1: 8.7;HDLM-2: 10.9;NTERA-2: 8.5;SCLC-21H: 11.1;SH-SY5Y: 6.9;U-2197: 6.7;U-251 MG: 11.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Cytosol Cytosol "HPA044791: , HPA060219: " "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 2.0 6.8 17.6 2.5 17.5 1.0 6.4 1.8 24.6 3.7 1.6 0.9 9.1 1.0 6.8 7.6 1.7 3.7 2.6 1.2 26.2 20.8 1.6 1.1 1.8 2.5 7.9 21.9 7.9 46.5 0.9 37.2 1.6 12.9 4.8 1.7 1.4 3.0 7.1 2.4 2.0 1.4 6.1 5.8 2.9 3.0 3.6 1.9 0.0 7.7 0.0 1.7 2.0 1.5 0.1 0.1 0.6 0.1 0.2 4.3 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 9.7 1.0 0.0 8.7 0.5 1.2 10.9 0.3 0.0 1.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 2.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 8.5 1.9 0.1 4.0 0.0 0.8 0.0 11.1 6.9 0.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 6.7 11.6 0.0 0.1 0.1 1.2 0.0 0.1 0.6 0.1 0.1 0.1 0.0 4.3 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.3 0.0 17.6 17.5 1.8 18.5 26.2 20.8 7.9 21.9 12.9 1.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 44.6;MCF7: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavourable (9.85e-4)" "prognostic favourable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 6.8 11.1 11.0 12.7 12.3 4.8 11.9 13.7 12.4 17.3 19.6 13.7 19.9 26.0 12.2 17.3 20.1 15.3 16.5 8.1 10.9 8.1 19.4 17.0 18.7 5.4 13.7 7.7 13.8 29.6 11.2 17.0 23.0 10.3 29.6 8.1 19.7 40.9 18.5 10.3 18.6 25.1 9.0 8.3 7.9 18.6 22.3 12.5 8.8 15.2 10.1 14.7 11.5 15.0 2.8 3.4 4.2 2.5 3.6 4.5 1.9 17.6 44.6 6.6 10.1 2.1 2.2 20.1 8.4 3.4 5.7 5.7 29.2 15.0 4.0 12.8 5.3 6.5 3.6 6.7 2.1 10.7 10.2 4.8 8.1 14.2 3.4 4.8 7.0 2.7 3.0 5.3 3.8 7.4 9.5 3.2 3.4 49.1 5.1 5.3 12.1 10.7 5.2 5.2 3.0 5.5 19.4 21.3 14.7 8.6 38.3 9.5 17.0 8.0 12.3 9.7 16.7 11.1 15.0 3.6 3.4 3.3 11.9 2.9 11.6 1.0 2.5 4.2 2.6 1.4 3.6 2.2 2.9 4.5 3.4 2.8 2.2 2.2 2.1 3.6 2.1 2.9 3.0 1.9 11.0 12.3 13.7 12.4 10.9 8.1 13.7 7.7 10.3 12.5 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537389-9839041 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.3" "Group enriched" "Detected in some" 9 "SCLC-21H: 10.0;SH-SY5Y: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.5 5.2 5.7 0.6 11.7 0.5 1.6 30.3 19.6 0.8 0.6 0.8 0.0 0.7 1.0 2.2 1.0 0.7 3.4 0.6 4.0 3.3 1.0 2.3 0.7 0.6 1.6 8.8 0.6 3.5 0.5 2.0 0.6 5.3 1.6 0.6 0.6 1.2 1.6 0.6 1.6 0.6 0.6 1.2 0.6 1.2 1.0 1.7 0.0 0.6 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 10.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 5.7 11.7 30.3 13.6 4.0 3.3 1.6 8.8 5.3 1.7 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40238759-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 22.2" "Cell line enhanced" "Detected in many" "CACO-2: 14.5;HaCaT: 22.5;hTCEpi: 13.8;SK-BR-3: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.3 5.3 14.7 0.8 18.4 0.8 2.3 11.3 20.1 3.0 1.3 1.6 2.5 1.4 1.0 1.1 15.8 4.3 1.4 7.9 11.6 5.2 3.4 0.4 2.6 1.0 3.0 10.9 0.6 7.4 12.9 6.4 8.1 2.1 3.6 1.2 0.3 3.4 7.5 3.5 22.2 1.4 0.8 1.2 1.0 3.6 12.8 2.2 0.0 7.4 8.5 5.1 3.0 5.1 1.4 0.7 2.9 0.7 2.0 5.5 1.2 2.6 0.0 0.2 0.1 0.0 0.0 4.3 0.0 0.1 0.6 0.4 14.5 2.0 0.1 2.3 0.0 22.5 3.2 4.8 0.2 0.1 0.7 0.0 1.9 0.1 0.0 0.1 0.3 0.0 13.8 0.2 3.2 0.0 1.1 0.2 0.0 3.1 0.0 0.3 0.4 2.0 0.2 0.1 1.8 1.1 5.9 5.2 1.3 1.8 7.6 0.2 0.8 7.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.5 0.3 0.1 2.1 0.7 2.9 5.5 0.3 2.1 1.4 0.5 4.2 0.7 0.5 0.3 1.2 1.3 2.0 0.2 0.5 0.1 1.2 14.7 18.4 11.3 20.1 11.6 5.2 3.0 10.9 2.1 2.2 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 304.2" "Cell line enhanced" "Detected in many" "ASC diff: 76.6;fHDF/TERT166: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" 59000000 "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: " "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favourable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavourable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 16.5 24.5 8.2 6.5 16.4 0.8 17.3 6.6 16.5 74.9 14.0 5.4 9.5 5.8 21.3 83.8 11.7 10.6 11.5 304.2 8.8 23.5 13.7 2.1 13.2 5.8 10.0 7.6 17.0 16.4 49.5 18.3 26.3 15.5 13.4 9.5 8.7 53.8 29.4 22.0 8.5 8.5 18.5 4.8 8.9 17.2 7.2 4.6 1.8 21.7 13.2 7.3 15.8 15.3 0.5 2.0 10.1 5.3 16.2 14.1 6.3 14.9 2.2 27.6 12.2 76.6 45.9 11.0 42.6 63.8 12.6 38.5 7.3 19.9 0.0 9.2 98.2 5.1 1.5 18.7 34.9 1.8 6.2 3.1 9.0 2.3 11.6 0.9 3.4 25.1 8.1 9.2 7.0 26.0 0.1 2.1 35.7 3.0 0.0 0.4 4.9 8.3 1.1 15.4 8.3 48.7 1.7 13.1 9.0 18.1 1.1 11.1 4.7 1.0 20.0 40.1 10.4 18.8 12.6 4.7 1.1 0.0 46.0 4.2 34.5 1.9 5.3 0.1 14.1 0.9 10.0 0.5 8.5 10.4 2.0 0.3 2.9 4.8 10.1 16.2 1.9 1.1 12.1 6.3 8.2 16.4 6.6 16.5 8.8 23.5 10.0 7.6 15.5 4.6 PAN2 "hPAN2, KIAA0710, USP52" ENSG00000135473 "PAN2 poly(A) specific ribonuclease subunit" Q504Q3 12 56316223-56334053 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (9.10e-3)" "unprognostic (1.03e-1)" "unprognostic (7.28e-2)" "unprognostic (7.35e-3)" "unprognostic (3.80e-1)" "unprognostic (1.74e-3)" "unprognostic (4.23e-3)" "prognostic unfavourable (2.77e-4)" "unprognostic (4.19e-1)" "unprognostic (3.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" 8.1 13.4 12.8 7.1 17.7 7.4 9.9 21.7 17.6 9.6 9.5 16.1 16.4 11.0 11.2 17.6 7.4 11.3 7.8 9.8 13.9 5.1 9.7 17.6 8.7 9.0 19.7 7.0 17.8 12.9 24.3 30.7 9.2 14.6 9.1 9.6 12.6 10.0 14.1 9.1 9.4 10.7 8.8 16.4 10.6 10.5 18.2 19.4 15.3 20.2 4.8 11.0 11.0 9.2 3.1 7.6 3.9 8.1 3.8 5.2 3.4 2.9 4.5 11.1 3.6 9.8 11.1 7.3 2.3 3.1 5.1 2.4 2.7 5.9 8.2 8.9 4.4 6.2 13.1 8.6 2.9 3.6 6.4 10.4 4.3 2.6 8.6 2.3 5.6 10.3 11.7 5.4 16.0 3.8 7.0 20.5 3.0 6.4 7.7 5.8 3.7 3.0 6.7 7.9 14.7 5.0 2.4 8.8 8.0 4.4 5.6 5.6 7.3 4.5 1.6 5.3 5.2 2.4 2.0 17.3 6.8 5.3 6.3 4.8 4.4 3.9 5.8 2.3 2.4 8.1 3.7 3.1 1.9 3.5 7.6 2.7 4.1 5.2 0.4 3.8 3.8 2.9 3.0 3.4 12.8 17.7 21.7 17.6 13.9 5.1 19.7 7.0 14.6 19.4 PARP1 "ADPRT, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360691-226408079 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm 39000 Nucleoplasm "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: , CAB075727: , HPA045168: " "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavourable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavourable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 17.3 16.6 31.2 35.7 31.2 14.3 15.3 21.1 29.2 14.3 21.8 37.4 10.3 15.0 18.2 13.0 18.1 15.0 10.8 24.2 27.8 21.9 13.4 24.8 14.1 56.3 40.7 21.8 14.6 28.1 62.6 22.9 28.7 30.4 22.0 19.2 16.3 17.0 24.7 47.3 11.7 19.6 25.5 49.1 32.7 15.9 22.5 34.8 29.5 14.5 16.5 70.2 19.9 13.7 53.0 16.5 9.0 17.5 11.1 21.8 11.5 28.5 15.3 42.6 30.1 11.2 9.2 24.3 18.9 16.9 25.8 21.2 24.3 14.0 83.2 28.3 11.5 21.5 58.5 18.6 22.7 34.9 81.7 32.2 20.4 15.9 6.7 53.4 15.6 9.1 7.4 20.7 14.7 20.0 51.2 42.5 13.3 13.6 17.1 19.3 78.4 30.4 51.8 73.0 76.9 12.1 20.4 42.9 37.6 24.6 27.6 15.5 23.2 33.5 15.2 13.7 22.7 18.5 35.4 17.3 29.0 71.5 11.4 18.1 30.7 9.0 6.7 6.9 18.3 11.3 21.6 46.8 19.4 18.0 14.3 53.0 15.2 16.4 1.0 11.1 17.5 16.5 21.8 11.5 31.2 31.2 21.1 28.4 27.8 21.9 40.7 21.8 30.4 34.8 PARP10 FLJ14464 ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.4" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "HPA028122, HPA052427" Approved Supported "Nucleoli,Golgi apparatus,Cytosol" Nucleoli "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: " "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 14.2 18.8 8.8 27.4 9.5 15.7 18.6 5.3 8.7 14.4 16.5 9.3 20.7 20.5 20.3 18.3 15.8 18.0 21.8 6.4 8.9 4.1 20.5 19.1 21.4 23.6 10.4 6.8 22.4 15.3 9.3 14.2 10.4 9.2 17.7 3.8 12.7 27.7 14.9 12.5 14.3 21.8 9.6 8.9 31.1 13.1 15.8 9.8 27.8 15.4 10.4 21.6 8.8 12.9 2.4 16.4 3.2 2.8 1.9 4.6 2.4 8.4 0.8 0.6 1.5 4.2 3.8 4.6 1.4 1.8 9.5 10.7 0.4 14.8 10.5 20.2 4.5 3.2 0.2 5.0 0.4 23.7 0.0 11.6 4.9 5.3 4.1 4.5 14.0 2.4 5.0 4.7 1.9 1.4 0.2 8.4 1.8 10.3 15.7 7.9 0.5 6.8 14.8 1.7 14.1 3.9 10.7 0.5 0.5 9.8 1.0 18.6 11.0 6.8 6.5 4.9 7.4 8.2 5.2 14.3 8.4 2.4 7.1 15.4 2.6 0.0 1.9 3.2 4.6 2.8 3.0 1.2 2.2 3.7 2.3 2.4 1.6 2.3 1.1 1.9 2.7 16.4 1.6 2.4 8.8 9.5 5.3 8.7 8.9 4.1 10.4 6.8 9.2 9.8 PARP11 C12orf6 ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: AB_1854980" "unprognostic (9.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.87e-2)" 7.1 14.5 11.2 8.6 9.2 3.7 8.3 11.0 9.1 6.4 5.4 5.6 4.8 4.9 10.2 7.5 5.0 6.3 5.6 5.1 6.1 5.7 5.7 5.7 6.3 12.8 5.0 5.7 13.1 6.6 10.0 10.4 4.1 7.6 12.0 5.7 7.2 6.6 6.0 4.1 3.9 6.5 7.2 6.1 9.2 4.2 12.8 5.6 16.9 12.3 2.7 12.1 8.3 5.8 10.7 10.2 18.3 10.2 8.2 12.5 7.1 2.5 2.1 13.6 2.1 4.3 6.9 3.8 3.0 5.1 5.3 5.3 7.8 2.0 7.4 1.9 6.6 2.1 4.5 4.5 8.6 14.9 4.5 10.6 0.0 5.7 4.9 7.1 4.0 5.5 3.5 4.2 11.8 3.9 2.8 6.0 7.4 3.5 3.8 2.7 5.0 0.3 7.6 9.3 1.7 2.5 5.7 0.9 3.1 2.9 2.6 3.9 0.5 6.5 7.7 4.6 4.5 7.0 4.0 2.9 6.3 10.5 4.4 4.0 1.2 18.3 10.2 10.2 9.2 8.5 12.5 10.7 10.2 6.7 10.2 10.1 11.7 9.4 10.2 8.2 6.4 8.9 4.3 7.1 11.2 9.2 11.0 9.1 6.1 5.7 5.0 5.7 7.6 5.6 PARP12 "FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023744-140063721 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 11.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm Nucleoplasm "HPA003584: AB_1079568, HPA063872: " "unprognostic (1.46e-3)" "unprognostic (2.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "unprognostic (6.74e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (2.30e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (7.51e-3)" "unprognostic (2.68e-1)" "prognostic unfavourable (4.12e-7)" "unprognostic (3.31e-2)" "unprognostic (2.76e-1)" "unprognostic (1.75e-2)" "unprognostic (6.01e-2)" 3.1 1.8 1.0 3.7 0.9 6.1 2.5 0.1 0.7 2.1 2.2 4.2 2.8 4.2 2.1 2.5 3.1 1.7 1.0 1.0 3.1 3.0 5.2 3.8 1.0 3.2 2.7 2.5 3.3 3.4 2.8 3.9 4.3 1.4 0.9 8.6 4.4 1.5 1.3 6.0 2.3 5.7 3.2 2.7 1.9 3.1 1.0 1.3 3.4 2.0 2.3 3.3 2.4 3.7 2.3 0.0 0.4 1.1 0.4 3.8 0.6 0.5 4.6 7.8 2.7 3.5 1.7 2.8 1.1 3.7 1.5 4.3 1.3 4.6 4.6 1.4 1.3 1.7 2.0 0.4 1.4 1.5 2.5 2.0 4.2 4.9 4.1 2.3 0.0 2.9 4.4 11.9 0.2 6.8 2.0 0.0 0.0 2.0 2.3 1.4 0.0 2.4 1.1 3.4 0.6 0.9 9.4 1.5 2.1 0.5 3.4 0.1 0.1 0.4 0.9 5.8 0.8 0.7 2.0 2.2 2.9 1.7 1.1 0.3 1.9 2.9 1.3 1.0 0.6 1.9 3.4 2.3 1.9 0.7 3.3 2.4 PARP14 "KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680618-122730840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 21.6 10.3 5.6 15.8 7.2 11.7 9.3 2.3 6.0 11.6 13.3 5.9 6.4 11.4 10.6 12.7 11.7 7.2 10.0 6.5 5.2 4.8 13.7 21.5 26.0 16.7 7.3 5.2 10.0 6.7 7.2 6.8 17.5 6.3 12.3 6.7 7.5 8.5 5.5 5.2 5.7 22.3 11.9 6.8 29.7 7.6 4.6 4.9 18.7 20.4 6.4 18.9 12.8 12.4 15.9 4.2 20.8 10.5 7.4 7.0 2.8 5.9 4.9 3.1 3.3 4.4 10.6 0.0 2.3 15.5 29.2 45.1 2.6 11.7 0.0 9.7 5.1 4.6 4.6 4.7 6.0 9.0 0.5 5.4 2.3 4.0 10.8 2.4 2.7 6.4 2.4 5.1 2.0 12.6 2.5 8.8 1.0 3.0 9.1 1.6 0.4 4.2 12.7 3.2 1.6 7.1 6.1 0.2 0.0 5.9 1.3 6.6 2.2 4.3 8.6 1.5 3.9 0.9 2.1 3.4 0.6 1.0 4.7 5.7 2.7 8.3 8.2 4.0 6.9 10.5 6.0 10.2 3.8 4.5 4.2 15.9 3.2 3.4 20.8 7.4 9.3 0.6 7.0 2.8 5.6 7.2 2.3 6.0 5.2 4.8 7.3 5.2 6.3 4.9 PARP15 "FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577602-122639047 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.9;lymphoid tissue: 40.4" "Cell line enhanced" "Detected in some" "HEL: 10.7;REH: 5.0;THP-1: 5.1;TIME: 12.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 9.3;MAIT T-cell: 6.5;memory B-cell: 11.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 6.4;naive B-cell: 11.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 5.9;NK-cell: 5.2;T-reg: 4.5" "Group enriched" "Detected in many" 6 "B-cells: 11.9;NK-cells: 5.2;T-cells: 9.3" "Low region specificity" "Detected in many" HPA035757 Approved Mitochondria "Intracellular and membrane" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 2.4 0.9 0.5 24.5 0.4 9.8 1.3 0.3 0.8 1.2 2.8 1.2 0.5 1.0 1.5 2.3 1.9 1.4 2.8 1.5 0.6 0.5 1.5 1.9 5.6 20.3 0.6 0.6 1.1 2.7 0.0 1.0 1.0 0.6 1.3 2.1 1.8 5.5 0.2 2.6 0.7 22.9 0.9 0.9 40.4 1.7 1.7 0.4 9.4 1.9 1.7 34.8 3.6 1.2 11.9 1.2 1.3 0.6 5.2 9.3 2.7 0.6 0.2 0.5 0.5 0.2 0.3 0.6 0.3 0.2 0.1 0.1 0.3 1.0 0.8 0.6 0.2 0.6 0.1 0.0 0.0 1.9 0.2 10.7 0.8 0.5 0.2 0.7 0.5 2.2 0.1 0.4 0.2 2.4 0.3 2.1 0.0 0.5 3.2 0.7 0.7 0.3 5.0 0.4 0.6 0.0 1.0 0.8 0.5 0.3 0.2 0.3 0.8 5.1 12.7 0.4 1.1 0.5 0.4 1.0 0.7 2.4 0.7 0.3 0.2 1.3 0.2 0.1 9.3 0.5 6.5 11.2 5.0 6.4 0.9 11.9 4.3 5.9 0.7 5.2 0.6 1.2 4.5 2.7 0.5 0.4 0.3 0.8 0.6 0.5 0.6 0.6 0.6 0.4 PARP16 "C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Enzymes, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" 8.9 14.2 12.0 13.1 11.6 8.0 20.4 32.2 17.7 18.6 12.8 5.6 11.9 9.3 13.1 8.5 10.5 12.0 8.7 7.2 9.7 5.3 9.0 18.1 11.5 14.0 11.5 6.2 17.6 11.3 12.7 8.5 9.2 9.1 11.5 10.4 7.5 10.3 21.4 5.4 10.8 9.7 17.7 8.0 9.3 11.0 7.6 12.0 15.1 9.5 6.3 12.4 14.0 25.6 10.1 4.4 14.1 5.3 10.3 14.2 6.0 3.8 4.0 4.4 6.9 3.6 3.8 1.9 1.7 4.7 5.0 5.2 3.2 3.5 12.5 4.9 2.2 6.3 20.3 2.5 3.7 4.5 8.1 2.1 4.3 4.5 6.8 5.7 4.0 4.4 4.2 1.3 5.1 4.6 5.1 4.8 4.3 4.6 11.8 6.1 2.0 5.4 21.9 8.0 9.5 3.5 3.5 7.6 5.1 5.5 5.3 4.5 6.2 5.2 1.8 5.9 4.5 3.3 2.7 8.9 10.5 16.4 4.9 8.5 2.7 14.1 3.3 10.0 11.6 5.3 12.9 7.8 11.2 11.8 4.4 10.1 14.2 10.5 13.0 10.3 5.2 3.9 9.2 6.0 12.0 11.6 32.2 17.7 9.7 5.3 11.5 6.2 9.1 12.0 PARP2 ADPRTL2 ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343582-20357905 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA052003: " "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavourable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 11.5 16.6 23.6 8.9 28.5 20.9 15.2 36.7 31.3 12.0 11.7 16.8 9.3 11.2 18.8 16.8 10.7 14.7 8.9 14.0 19.2 17.8 14.0 15.0 12.0 11.8 16.6 30.8 20.2 11.8 11.6 14.6 11.3 22.1 11.3 12.9 10.8 10.5 12.9 25.9 15.1 10.8 14.6 13.9 11.4 11.6 20.4 17.4 6.0 11.7 13.9 15.2 9.3 10.4 6.7 5.6 1.8 5.0 6.9 12.3 4.9 20.2 14.8 22.8 17.1 7.6 7.2 16.6 22.5 12.3 28.6 35.5 13.9 19.4 15.0 10.2 7.1 19.0 30.3 10.3 33.9 12.0 14.8 13.7 17.9 23.3 6.8 28.3 7.9 5.0 8.8 17.8 19.7 14.7 14.5 20.5 19.6 12.5 14.5 12.2 12.5 23.1 18.2 31.0 9.7 11.4 10.6 15.8 10.9 25.1 14.0 6.6 12.9 9.6 10.0 17.5 26.5 12.0 18.2 19.2 24.5 19.9 7.3 12.6 19.3 1.8 5.0 0.5 9.5 4.5 12.3 6.7 8.9 8.3 5.4 4.6 9.6 9.3 0.1 6.9 2.5 5.6 5.2 4.9 23.6 28.5 36.7 31.3 19.2 17.8 16.6 30.8 22.1 17.4 PARP3 "ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: " "prognostic favourable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favourable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 15.2 29.2 11.2 14.6 17.1 2.8 13.6 5.7 18.8 7.5 17.3 10.6 14.3 26.9 10.3 14.1 10.8 12.1 16.2 12.4 11.6 12.3 17.3 22.3 13.3 9.7 12.0 14.2 8.2 3.9 34.2 9.8 6.2 12.2 12.1 10.7 13.2 14.0 18.1 14.6 6.1 26.3 18.9 8.7 12.8 15.8 4.5 10.2 2.9 17.0 9.6 10.3 15.1 8.9 9.0 2.9 1.7 4.1 6.6 4.9 2.3 6.0 3.3 1.0 9.0 8.7 16.5 2.5 9.8 15.9 12.2 13.7 1.9 15.9 8.2 2.6 16.2 0.9 2.5 8.9 5.9 20.0 0.6 4.2 6.7 6.3 9.5 2.5 5.8 13.1 5.5 7.7 5.2 6.1 1.7 7.7 9.3 1.5 2.2 6.3 1.3 9.6 3.5 1.5 7.0 7.4 6.6 1.0 3.4 9.9 2.8 5.3 3.4 2.8 13.7 24.5 5.1 3.6 5.9 11.8 14.3 3.5 15.8 7.4 7.6 0.0 2.6 1.7 3.6 4.1 3.4 9.0 4.2 2.8 2.9 4.3 4.9 4.9 0.1 6.6 2.0 1.2 4.3 2.3 11.2 17.1 5.7 18.8 11.6 12.3 12.0 14.2 12.2 10.2 PARP4 "ADPRTL1, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420926-24512810 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011739 Approved Supported Cytosol Cytosol "HPA011739: AB_1854986" "unprognostic (1.61e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-2)" "unprognostic (4.35e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (4.12e-3)" "unprognostic (2.97e-2)" "prognostic favourable (1.21e-5)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.80e-2)" "unprognostic (2.84e-3)" 25.3 24.7 6.6 16.7 12.9 11.6 14.6 2.3 7.0 17.8 39.4 16.7 21.6 22.9 19.1 11.2 22.2 14.9 23.8 11.3 7.9 5.6 28.8 17.3 17.8 16.5 14.6 4.4 15.9 15.5 11.2 12.6 14.8 12.5 16.1 24.1 14.0 17.7 30.9 6.5 10.2 49.9 15.5 20.5 28.4 20.4 7.0 12.1 28.8 18.2 11.3 26.2 23.3 13.2 9.0 16.4 26.1 18.6 11.8 12.9 10.6 15.0 13.5 6.6 11.9 18.3 26.1 5.6 17.5 23.0 15.4 13.8 5.5 39.2 11.2 17.5 15.9 17.5 9.8 17.7 12.6 25.8 6.9 16.1 12.5 12.6 10.4 20.6 16.0 15.0 6.0 12.7 6.8 25.2 4.5 5.0 18.2 6.9 13.0 9.9 7.5 16.7 12.3 12.4 15.8 28.6 31.0 6.0 7.7 12.8 5.2 12.1 2.5 17.1 35.7 7.0 7.3 8.9 17.8 5.7 6.6 14.8 12.7 10.9 15.2 25.2 12.4 26.1 12.9 15.3 12.9 9.0 10.8 12.8 16.4 5.1 8.1 9.6 14.3 11.8 18.6 6.2 12.7 10.6 6.6 12.9 2.3 7.0 7.9 5.6 14.6 4.4 12.5 12.1 PARP6 pART17 ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favourable (3.17e-5)" "prognostic unfavourable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavourable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 13.7 16.6 28.0 12.8 32.4 25.1 26.5 46.6 41.2 15.5 16.2 16.9 18.2 14.1 23.3 23.8 14.0 17.0 20.2 18.4 26.1 22.4 14.3 9.0 15.7 16.8 19.9 21.8 26.3 20.9 20.6 30.8 17.0 19.4 19.3 14.3 14.5 21.3 18.8 23.9 20.3 14.4 19.6 14.2 18.2 18.2 25.1 15.8 9.6 21.7 12.5 15.8 16.3 15.8 4.1 4.0 12.1 5.3 4.3 4.3 2.9 7.2 13.1 13.8 17.9 14.8 12.4 11.2 6.2 9.4 10.3 15.2 8.6 13.2 10.0 3.9 9.4 9.5 15.2 8.4 5.9 11.8 13.7 14.5 22.9 0.1 12.4 7.4 13.9 15.9 20.8 9.6 26.6 6.9 7.3 11.5 8.3 13.2 6.3 13.1 6.4 0.0 11.8 9.8 7.8 9.6 14.4 39.0 20.7 10.4 8.5 17.0 10.8 8.6 6.5 13.0 11.9 16.9 9.4 13.0 11.9 10.8 9.4 14.6 9.0 1.7 5.3 12.1 3.8 4.4 2.7 3.3 2.7 4.0 4.0 4.1 4.3 3.2 5.7 4.3 4.9 3.1 4.2 2.9 28.0 32.4 46.6 41.2 26.1 22.4 19.9 21.8 19.4 15.8 PARP8 "FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846522 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: " "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favourable (1.12e-4)" 6.2 7.8 8.8 17.1 9.5 33.5 5.3 2.4 18.7 5.6 5.5 3.3 0.6 6.8 5.2 5.4 5.2 7.4 12.3 3.6 12.8 8.0 5.8 4.2 10.9 18.2 4.9 11.0 5.9 7.1 9.8 14.4 5.6 5.4 6.1 4.3 4.1 7.6 4.2 1.7 4.2 14.2 5.4 7.0 20.1 10.2 6.4 2.8 9.9 21.9 1.1 12.3 8.8 7.0 7.1 3.9 13.1 5.9 15.5 32.0 9.5 11.7 0.0 5.4 8.6 1.5 2.7 8.6 1.9 7.0 1.9 5.6 0.3 15.4 6.9 8.2 0.2 5.8 0.9 5.9 4.5 9.7 7.5 5.1 4.7 0.5 2.9 11.9 0.1 3.3 4.9 3.8 2.7 0.1 0.7 4.2 2.6 3.8 14.3 15.1 5.8 2.9 7.2 11.5 8.0 3.5 5.8 6.0 9.3 6.3 10.3 1.6 0.4 42.2 0.0 0.4 7.3 0.5 5.7 3.1 0.1 13.5 6.5 3.4 8.0 10.3 5.9 13.1 20.6 1.6 32.0 6.0 16.1 23.0 3.9 7.1 10.0 16.7 12.3 15.5 1.1 1.8 9.5 9.5 8.8 9.5 2.4 18.7 12.8 8.0 4.9 11.0 5.4 2.8 PARP9 "BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 34.9;BJ hTERT+ SV40 Large T+ RasG12V: 41.8;SK-MEL-30: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Cytosol" Mitochondria "HPA066708: " "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favourable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 27.1 20.2 8.7 17.2 12.4 9.1 13.8 2.9 13.9 13.1 13.1 9.9 7.4 10.4 23.3 10.1 15.6 12.3 14.9 8.5 7.4 6.0 17.8 38.6 18.9 17.5 8.5 6.0 12.1 14.4 16.0 20.3 11.9 10.3 15.1 10.1 11.5 19.1 6.6 8.6 5.7 21.2 14.8 16.3 27.3 11.1 5.4 10.3 21.8 17.5 9.0 19.1 13.7 9.8 7.3 11.9 38.2 18.0 13.0 10.6 9.1 8.0 2.7 1.0 0.7 6.2 13.0 0.9 2.7 14.7 34.9 41.8 4.2 8.9 1.8 6.0 5.4 8.9 2.3 4.8 7.3 13.9 1.6 8.7 2.8 2.2 6.7 2.8 5.8 10.5 4.7 4.9 1.2 7.4 0.8 7.5 1.4 3.5 8.9 3.5 0.4 7.6 9.5 9.9 0.6 13.4 4.6 0.6 2.4 7.1 1.2 32.3 3.8 3.1 4.4 1.5 4.4 0.3 1.6 4.6 2.4 3.3 5.2 3.0 2.7 14.4 12.7 15.3 9.2 17.7 8.6 7.3 9.8 10.3 11.9 5.0 7.5 9.1 38.2 13.0 18.0 1.4 10.6 9.1 8.7 12.4 2.9 13.9 7.4 6.0 8.5 6.0 10.3 10.3 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 4.9 6.7 9.1 11.5 0.7 1.4 12.1 4.8 1.5 4.4 6.2 5.4 5.0 2.6 1.0 1.1 12.5 10.3 4.1 3.2 10.4 9.7 7.1 12.4 9.6 0.5 9.7 11.2 0.6 3.3 4.6 1.3 3.1 9.2 3.5 3.1 5.6 11.5 10.2 10.1 4.1 18.3 9.2 3.2 1.7 11.2 16.1 4.9 2.8 5.5 2.1 4.6 7.0 4.1 6.1 5.5 7.7 6.4 4.8 4.8 12.2 3.8 7.3 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Cell line enhanced" "Detected in many" "A-431: 60.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavourable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavourable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 60.7 19.8 19.5 12.3 1.9 3.4 8.2 27.9 13.3 28.8 24.3 6.9 11.3 32.4 9.9 10.7 16.1 18.7 9.4 31.6 7.9 10.2 7.8 14.1 10.0 0.1 5.0 11.6 0.9 7.7 13.3 7.1 14.5 11.4 21.8 33.9 6.9 19.2 5.9 3.5 17.2 12.0 27.2 8.7 10.8 9.4 7.7 12.1 10.4 12.2 15.6 12.9 7.7 8.4 18.9 45.6 23.9 29.6 3.1 8.6 15.0 11.5 8.9 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol 8200000 Cytosol "HPA003239: AB_1079580" "prognostic unfavourable (4.02e-7)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavourable (1.88e-4)" "prognostic unfavourable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavourable (6.38e-4)" 19.1 18.4 35.7 13.0 43.0 28.5 19.3 33.5 58.3 20.2 16.9 19.2 12.4 14.7 16.0 22.2 17.9 15.8 11.0 43.9 35.0 38.8 21.3 29.5 15.1 14.6 35.1 46.0 16.2 14.6 16.4 15.5 17.2 57.4 22.1 18.1 11.6 17.2 21.4 69.5 14.7 13.6 19.6 28.6 12.0 12.7 29.1 19.2 18.1 19.3 15.9 17.9 14.4 13.7 31.6 53.0 51.2 58.0 30.0 37.4 51.6 21.4 17.0 17.4 21.8 37.5 31.0 19.4 35.3 20.2 28.1 35.5 49.3 16.4 27.2 30.0 29.8 26.8 29.9 35.2 40.6 18.9 43.3 41.5 32.0 48.2 25.1 49.4 51.1 15.4 26.1 32.0 34.6 26.5 59.3 26.7 33.5 63.9 24.0 37.7 14.2 19.1 19.9 22.6 19.5 27.3 15.8 33.2 12.8 26.8 42.8 22.9 25.9 35.2 19.7 16.6 21.0 31.4 38.3 16.9 26.2 27.8 26.1 33.0 32.8 40.0 58.0 51.2 30.2 53.6 30.1 31.6 30.6 32.7 53.0 24.2 28.5 32.5 30.8 30.0 52.2 23.9 37.4 51.6 35.7 43.0 33.5 58.3 35.0 38.8 35.1 46.0 57.4 19.2 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm Nucleoplasm "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 24.8 22.2 15.3 19.9 18.7 25.8 18.0 14.2 17.8 13.6 25.3 23.0 21.1 41.1 18.2 18.7 25.2 15.0 19.8 36.0 14.8 13.8 20.2 17.8 18.7 15.6 16.6 14.1 15.6 13.9 16.0 12.1 14.2 20.5 13.3 16.5 14.4 17.1 19.2 45.8 32.8 37.2 19.5 18.3 23.4 18.1 19.4 18.6 13.2 14.8 28.0 19.0 17.6 16.7 7.8 8.7 20.5 9.8 7.9 13.5 4.6 28.2 11.4 8.0 11.7 16.4 18.3 12.1 21.6 15.4 18.6 16.4 27.8 10.3 7.2 72.5 24.7 22.1 12.7 16.6 15.9 13.2 8.9 20.8 12.0 11.8 14.7 10.0 17.9 15.4 12.7 18.0 12.9 19.9 11.6 16.2 18.5 23.8 6.2 5.3 6.9 17.0 10.4 10.2 11.6 11.4 15.9 7.8 5.8 14.6 25.3 14.0 37.1 12.5 29.6 14.8 8.2 20.1 29.2 15.0 28.6 13.4 22.7 14.0 18.6 7.5 8.7 9.2 9.6 9.2 8.0 7.8 7.2 10.2 8.7 5.7 4.6 6.8 20.5 7.9 9.8 5.6 13.5 4.6 15.3 18.7 14.2 17.8 14.8 13.8 16.6 14.1 20.5 18.6 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 15.6" "Cell line enhanced" "Detected in some" "AF22: 8.2;CACO-2: 17.6;HEL: 21.6;Hep G2: 9.0;NTERA-2: 9.3;SCLC-21H: 6.4" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 2.7;neutrophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.8 1.1 12.0 1.1 11.4 2.0 1.0 3.1 23.9 1.6 1.1 13.7 2.3 1.3 3.2 1.7 2.8 5.7 1.7 4.2 10.0 6.0 1.0 0.6 2.1 0.6 7.8 10.5 4.0 3.1 0.7 1.4 3.6 10.7 2.3 1.3 2.1 1.0 6.4 0.7 0.7 1.1 6.1 10.3 1.0 0.9 15.6 8.7 0.0 0.6 0.0 0.7 0.9 0.4 0.4 0.5 2.7 0.5 0.6 0.2 1.4 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 17.6 0.0 0.0 4.6 0.0 0.9 3.8 0.0 0.0 0.0 0.1 21.6 0.0 9.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.5 9.3 0.0 0.0 1.1 0.0 0.0 0.0 6.4 5.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.2 0.6 0.2 2.7 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.2 0.2 2.2 0.6 0.5 0.5 0.2 1.4 12.0 11.4 3.1 11.3 10.0 6.0 7.8 10.5 10.7 8.7 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900965-81911464 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 70.8" "Cell line enhanced" "Detected in all" "Hep G2: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Supported "Intermediate filaments,Centrosome" 7000 Centrosome "Intermediate filaments" "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favourable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 13.6 5.5 13.3 5.7 12.7 5.3 10.4 12.2 17.0 6.5 16.2 13.4 6.4 30.7 5.8 8.6 7.6 12.2 8.0 17.7 14.0 11.8 21.7 46.5 7.2 6.3 13.4 16.0 7.8 11.5 8.2 4.6 6.0 15.9 10.1 8.5 5.8 10.8 6.6 13.5 4.5 26.5 5.0 14.3 4.1 11.5 70.8 11.0 5.6 6.7 6.8 5.8 7.5 4.4 7.3 6.6 2.1 3.5 4.7 8.4 4.0 12.1 7.0 5.6 15.8 28.2 14.9 8.3 8.7 18.8 12.3 14.6 27.4 12.7 4.2 4.8 9.1 10.0 8.5 16.2 7.1 1.2 6.9 9.2 9.6 62.6 30.2 9.2 7.7 12.2 9.4 11.1 8.6 11.3 17.0 8.8 9.1 10.3 10.9 11.4 4.5 7.5 7.2 6.0 15.0 14.7 23.0 7.2 6.6 6.6 36.4 8.5 10.1 21.9 7.6 9.1 6.0 6.8 7.2 5.7 2.4 4.1 9.4 12.4 8.9 2.1 3.5 1.2 7.1 3.4 4.6 6.0 8.4 7.2 6.6 7.3 7.0 7.2 1.0 4.7 3.0 6.5 5.0 4.0 13.3 12.7 12.2 17.0 14.0 11.8 13.4 16.0 15.9 11.0 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69328621-69330595 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Mitochondria Nucleoplasm "HPA063409: " "unprognostic (4.28e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavourable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favourable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 6.6 7.9 4.8 7.8 4.5 5.3 4.8 3.1 6.9 3.6 7.6 3.8 3.3 7.1 5.3 5.6 8.4 4.4 6.5 3.8 4.6 3.3 14.9 30.2 3.7 7.0 3.0 5.2 5.0 14.2 8.2 3.9 4.9 4.4 5.3 4.1 4.3 12.8 4.6 10.4 6.0 5.2 3.4 2.3 5.0 8.3 3.7 2.0 10.2 7.3 9.2 6.2 3.7 4.0 10.3 3.2 2.5 2.8 1.7 6.9 1.5 8.9 6.0 1.2 2.9 1.8 1.3 10.6 7.5 2.0 5.4 4.7 14.9 6.4 16.6 10.0 2.6 12.9 3.7 4.0 2.2 4.0 30.8 8.4 5.7 21.3 3.7 11.7 6.7 2.8 7.1 4.8 2.3 3.1 20.2 1.9 2.9 11.5 9.1 12.3 7.7 11.1 21.6 1.9 15.4 4.3 5.6 10.3 8.2 13.0 2.2 6.3 12.8 3.8 4.6 4.6 8.8 5.4 8.7 15.7 10.4 19.6 3.1 8.7 6.0 0.0 2.8 2.5 1.2 1.6 3.1 4.3 3.9 3.9 3.0 10.3 6.9 2.5 0.0 1.7 1.5 3.2 3.0 1.5 4.8 4.5 3.1 6.9 4.6 3.3 3.0 5.2 4.4 2.0 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283152-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "pancreas: 286.5" "Cell line enhanced" "Detected in some" "HAP1: 5.1;HEK 293: 11.3;Hep G2: 8.4;Karpas-707: 3.9;MCF7: 6.0;SH-SY5Y: 4.9" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Region enhanced" "Detected in many" "cerebellum: 15.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 0.3 0.3 2.1 0.2 1.5 0.3 0.2 15.3 3.0 0.2 0.7 4.3 0.2 2.9 0.2 0.3 0.2 0.2 0.8 0.4 2.8 3.0 0.2 0.2 0.2 0.2 4.0 0.5 0.4 286.5 0.2 0.2 0.5 2.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 1.0 0.2 5.4 0.2 10.2 0.3 2.8 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 5.1 0.2 0.6 0.1 11.3 0.0 0.3 8.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 3.9 0.2 6.0 0.2 0.6 0.4 0.0 0.1 0.0 1.1 0.0 0.0 2.2 4.9 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.5 15.3 3.0 2.8 3.0 4.0 0.5 2.2 2.8 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746392-43773279 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" 390000000 "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: , HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favourable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavourable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 16.9 21.2 10.0 20.5 13.5 20.8 31.1 12.7 9.2 24.7 19.4 12.3 33.9 22.2 19.7 42.4 21.7 18.4 25.1 20.6 10.2 12.7 27.3 112.5 20.0 34.6 12.4 10.3 22.4 46.8 21.1 21.7 44.0 13.3 24.6 21.2 13.7 43.4 36.9 8.7 17.9 28.8 15.8 11.4 25.2 20.5 17.1 14.3 15.6 74.0 16.4 19.8 14.7 28.3 7.7 18.3 13.5 10.8 11.7 14.1 14.5 12.2 4.6 9.7 21.8 19.8 21.2 29.9 24.6 24.3 18.3 22.7 12.8 12.6 14.0 16.0 28.0 19.5 12.3 23.8 15.9 10.1 18.2 18.9 7.3 11.8 32.5 10.7 13.8 13.6 19.7 13.8 23.3 31.8 10.9 6.9 17.8 4.2 3.6 12.1 9.8 18.6 7.0 15.3 10.5 15.5 10.0 9.8 10.9 20.5 19.7 7.7 13.7 10.9 21.5 15.2 8.0 12.2 11.9 3.1 3.6 14.7 19.5 16.9 11.4 10.0 10.3 13.5 13.4 10.5 14.1 6.5 8.5 10.8 9.6 7.7 7.2 8.4 2.9 11.7 10.8 18.3 6.7 14.5 10.0 13.5 12.7 9.2 10.2 12.7 12.4 10.3 13.3 14.3 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028641 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 164.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" 12000000 "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavourable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavourable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 17.6 13.0 7.7 25.6 11.9 7.4 27.4 5.1 7.9 25.5 20.9 12.1 28.8 18.2 19.4 46.3 15.2 20.8 28.1 16.9 7.3 8.0 27.7 164.3 19.1 29.1 11.6 6.2 19.4 76.3 7.0 19.1 24.7 12.0 18.0 21.9 7.8 36.4 26.5 5.8 10.1 21.3 17.8 13.9 27.9 23.7 11.5 11.3 19.2 89.8 11.9 24.3 17.4 22.6 26.6 63.3 16.2 21.2 21.5 35.9 34.5 32.6 31.1 33.8 94.5 30.9 22.1 49.0 46.0 30.8 26.4 43.1 25.8 88.4 23.5 103.3 37.8 21.4 22.8 43.6 23.2 16.7 13.4 11.3 9.0 56.5 41.5 25.7 31.9 21.7 19.6 28.9 23.2 53.5 18.4 64.2 23.1 35.7 24.4 29.3 50.4 18.1 16.1 26.2 57.0 30.8 25.7 10.8 28.4 41.7 30.1 16.0 17.1 19.8 29.2 20.8 11.8 50.5 32.3 48.9 22.0 16.6 48.6 30.4 70.8 16.2 20.1 12.1 34.3 21.2 35.9 26.6 22.6 26.7 19.4 15.1 21.5 22.7 2.7 21.5 21.0 63.3 16.6 34.5 7.7 11.9 5.1 7.9 7.3 8.0 11.6 6.2 12.0 11.3 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067062-123225227 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" 2900000 "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favourable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavourable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 11.6 17.1 2.6 11.2 3.1 6.3 9.3 1.0 4.0 10.0 11.0 2.4 10.9 5.6 12.2 17.1 6.7 9.1 22.2 7.2 2.5 1.2 11.0 66.0 14.4 7.1 2.2 1.8 11.4 18.3 5.2 12.1 29.1 1.9 14.3 10.8 12.7 10.8 7.6 8.1 6.1 8.2 9.5 2.3 8.6 17.6 18.0 2.5 3.2 18.2 5.5 7.9 7.8 6.9 3.2 12.8 0.3 9.0 0.5 2.4 2.3 8.1 5.0 6.3 7.6 28.9 26.2 33.6 15.5 26.0 8.7 24.0 16.0 7.5 0.0 20.3 24.0 4.3 2.7 9.4 9.2 0.2 3.1 3.6 1.5 19.1 12.0 8.9 0.5 22.5 14.2 5.9 12.4 29.4 4.5 21.3 5.9 9.9 2.4 10.5 4.6 5.2 2.3 4.5 22.5 7.3 4.8 6.8 4.1 7.5 8.5 13.3 7.4 11.0 16.3 2.2 7.1 10.5 4.2 6.3 1.6 3.6 7.2 7.1 7.5 0.0 9.0 0.3 1.4 2.2 2.4 3.2 1.0 0.9 5.4 0.8 0.6 0.6 0.2 0.5 0.4 12.8 0.0 2.3 2.6 3.1 1.0 4.0 2.5 1.2 2.2 1.8 1.9 2.5 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" 53000000 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (1.20e-4)" "prognostic unfavourable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavourable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 26.9 32.7 16.7 25.0 29.9 19.9 28.7 11.3 16.8 33.4 26.1 13.9 53.7 20.4 30.4 76.1 27.1 25.5 22.4 32.7 14.2 13.9 42.1 118.4 30.4 36.3 17.8 12.7 26.5 141.6 24.9 23.3 39.5 19.0 22.6 30.1 14.6 53.4 45.0 15.7 16.1 28.4 26.5 14.3 35.1 30.9 12.4 19.5 18.1 97.9 20.1 29.7 21.9 30.6 45.2 61.0 52.0 46.2 51.5 52.2 59.7 33.9 36.9 52.9 82.9 68.1 58.9 94.0 82.7 76.8 43.4 58.5 52.3 67.1 55.2 58.2 80.8 27.9 39.7 69.2 46.7 43.2 31.3 44.7 28.9 84.9 73.7 45.8 33.6 42.5 53.2 42.0 75.8 97.8 38.4 119.1 42.8 40.2 17.6 47.5 44.1 29.2 42.3 53.9 99.9 61.8 41.1 33.9 67.9 32.6 47.8 46.4 16.9 77.7 48.0 40.8 52.1 36.7 47.8 112.4 69.3 35.8 55.1 57.6 57.0 52.0 44.4 20.5 47.5 46.2 52.2 45.2 37.7 44.7 48.6 33.1 18.4 31.0 8.1 51.5 33.9 61.0 37.7 59.7 16.7 29.9 11.3 16.8 14.2 13.9 17.8 12.7 19.0 19.5 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 31.3;U-87 MG: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 5.9;granulocytes: 16.0;T-cells: 15.8" "Low region specificity" "Detected in all" "CAB017554, HPA027376, HPA059083" Approved Approved Nucleoli,Mitochondria 22000 "Nucleoli, Mitochondria" "CAB017554: AB_2161138, HPA027376: AB_1855139, HPA059083: " "unprognostic (2.14e-1)" "prognostic unfavourable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavourable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 9.9 16.2 6.8 11.0 10.5 13.4 16.7 7.1 15.6 7.3 15.3 3.3 2.9 15.5 5.4 8.0 11.2 4.4 5.8 27.6 6.9 5.2 6.8 14.2 6.1 21.4 7.2 5.2 19.5 7.2 3.4 7.5 7.9 7.2 6.5 13.1 7.6 14.1 7.6 9.6 24.7 8.4 5.2 10.7 14.2 12.5 11.0 6.7 10.3 5.1 5.0 20.8 18.0 9.8 5.9 2.3 16.0 2.2 1.4 15.8 6.2 14.1 0.6 3.7 9.1 1.5 2.3 5.2 12.5 10.1 6.3 13.4 3.6 3.0 13.5 6.9 3.8 6.2 2.5 7.8 20.1 2.7 5.0 16.4 3.3 4.2 2.7 8.1 6.1 2.9 2.8 4.3 7.3 3.3 3.4 9.3 8.3 1.4 5.1 10.2 8.9 3.9 5.4 6.0 21.7 3.2 4.6 6.9 7.9 3.2 3.8 4.7 2.4 3.4 3.8 10.0 3.2 5.2 3.3 31.3 18.1 11.1 32.0 5.9 2.0 12.2 2.2 16.0 2.5 1.5 3.0 4.7 4.2 2.8 2.3 5.9 15.8 9.6 8.5 1.4 1.9 0.4 8.0 6.2 6.8 10.5 7.1 15.6 6.9 5.2 7.2 5.2 7.2 6.7 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favourable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.4 11.3 10.1 11.9 9.0 1.2 7.1 10.5 10.6 10.3 0.9 7.1 8.2 11.9 19.8 3.1 7.5 2.8 10.5 16.5 10.4 7.3 9.2 6.9 6.4 0.0 8.0 18.9 11.0 6.9 0.5 9.2 2.9 8.2 6.0 8.3 6.1 0.0 2.4 9.1 9.2 25.2 11.1 5.8 5.5 7.5 11.4 10.0 3.2 4.7 18.5 7.3 4.7 12.5 10.3 8.5 5.1 16.2 15.3 4.4 18.3 2.6 8.0 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465221-24539837 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria Mitochondria Nucleoli "HPA046583: , HPA072492: " "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 9.6 5.6 5.7 9.8 17.3 16.3 12.8 3.3 23.6 8.0 14.7 5.5 5.6 13.6 7.3 15.7 9.5 13.2 7.0 16.9 12.5 6.8 13.7 11.1 11.2 13.4 6.2 13.7 11.0 7.3 12.8 14.1 7.7 14.9 8.3 10.1 9.9 19.3 5.2 3.9 14.2 15.6 8.6 6.1 17.9 12.7 23.1 4.8 12.5 6.2 4.1 14.9 10.3 9.2 4.5 7.2 36.4 10.9 7.1 11.0 6.7 9.0 4.6 3.9 6.5 0.1 0.0 4.1 2.7 2.4 3.7 6.5 0.4 11.0 9.1 1.8 0.7 2.0 11.3 6.9 9.9 7.8 5.4 4.9 5.3 2.6 1.3 4.1 4.8 0.7 3.0 0.9 0.9 5.5 0.9 13.9 0.5 16.9 7.8 5.4 7.0 5.4 4.0 7.0 13.4 3.2 17.6 2.5 3.2 14.7 6.0 4.5 8.2 1.6 0.1 2.6 3.8 4.8 3.2 8.9 6.8 11.0 7.1 6.4 5.3 9.4 8.9 21.3 7.6 10.9 11.0 4.5 6.2 6.2 7.2 4.1 4.9 5.7 36.4 7.1 10.4 2.3 5.1 6.7 5.7 17.3 3.3 23.6 12.5 6.8 6.2 13.7 14.9 4.8 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell line enriched" "Detected in some" 7 "ASC diff: 104.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056731 Approved "HPA056731: " "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 7.8 0.3 2.0 104.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.3 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.0 0.5 0.1 0.5 0.0 0.6 1.6 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926066 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 33.2;TIME: 33.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 38.9;cerebral cortex: 62.2;olfactory region: 32.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavourable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favourable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 5.1 32.3 11.0 4.6 38.9 5.9 7.9 7.5 62.2 7.5 4.3 4.7 1.6 3.3 7.7 8.6 8.0 6.1 9.6 22.9 10.1 8.0 6.3 2.2 6.0 5.6 5.1 32.5 9.7 9.3 20.6 4.2 6.6 4.4 5.2 6.2 4.4 6.6 4.7 31.8 3.2 5.5 5.5 3.4 5.8 5.5 12.9 4.8 4.1 9.3 7.0 5.8 7.7 5.1 11.0 12.7 7.8 21.5 2.8 19.5 8.8 8.9 4.4 9.6 4.0 8.0 14.6 3.2 7.0 7.8 8.3 9.8 4.6 33.2 5.0 23.7 11.2 19.9 4.1 5.9 12.3 0.5 2.0 2.3 5.5 1.6 9.1 1.1 3.3 9.4 11.8 14.1 22.6 18.7 0.8 8.2 10.1 2.1 6.9 3.6 4.4 5.7 1.7 5.7 0.9 5.7 6.2 0.8 4.2 4.6 0.5 21.6 1.5 1.4 33.2 10.1 6.5 23.6 8.3 4.6 1.9 4.2 12.9 4.2 8.9 3.1 15.4 7.8 5.6 14.3 5.3 9.3 9.1 7.2 12.7 11.0 5.5 4.8 1.8 2.8 21.5 2.1 19.5 8.8 11.0 38.9 7.5 62.2 10.1 8.0 5.1 32.5 4.4 4.8 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Supported Mitochondria Mitochondria "HPA019950: AB_1855156, HPA062059: " "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favourable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 10.7 7.2 7.4 3.7 10.5 3.2 8.7 11.5 16.5 4.9 7.5 10.1 5.7 10.4 7.9 7.2 8.9 7.2 6.0 4.8 7.4 7.1 18.1 16.5 8.6 5.0 9.0 9.4 14.9 13.8 12.0 7.0 7.7 16.0 7.8 8.4 8.5 7.1 6.9 6.3 4.7 6.2 4.6 6.3 4.0 6.7 8.6 8.9 4.6 18.0 4.0 5.9 6.3 5.5 3.3 1.3 1.8 0.4 6.1 6.3 2.0 7.2 8.8 5.5 10.7 14.7 7.6 6.9 3.7 14.7 8.8 13.2 17.9 5.1 10.0 5.4 5.3 9.1 15.8 8.5 8.5 2.3 8.0 5.0 4.4 11.6 8.0 6.4 8.9 5.7 6.4 12.4 12.9 3.7 9.6 7.2 7.8 4.7 12.5 4.6 6.4 11.2 12.3 7.6 15.8 4.6 7.7 11.0 6.2 12.1 5.0 4.5 6.6 3.1 3.5 5.4 7.3 3.2 5.5 12.8 11.8 10.0 7.4 5.1 5.3 1.3 0.4 1.8 6.3 0.3 5.2 1.8 3.1 5.1 1.3 3.3 4.5 5.0 1.3 6.1 0.2 0.8 0.9 2.0 7.4 10.5 11.5 16.5 7.4 7.1 9.0 9.4 16.0 8.9 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199, HPA068961" Supported Approved Vesicles Vesicles "CAB004272: AB_626657, HPA035199: , HPA068961: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favourable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.4 10.8 13.5 9.0 14.0 11.7 14.3 14.0 9.1 12.6 10.6 10.8 10.1 13.9 9.6 13.6 13.4 16.1 10.1 12.0 24.7 10.9 7.3 14.3 17.9 12.2 12.1 19.4 10.6 18.6 13.5 9.1 11.5 13.6 11.3 14.7 17.8 12.2 8.5 8.5 9.7 25.0 13.5 12.5 12.2 7.5 21.3 11.0 18.2 21.0 7.5 19.4 15.3 14.1 13.8 13.7 13.4 12.1 15.1 14.3 21.7 6.6 8.4 11.9 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" Mitochondria "CAB068215: , HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavourable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 12.2 16.5 11.7 14.3 14.0 12.5 18.6 14.6 22.1 8.4 13.9 8.3 9.9 13.6 10.4 9.9 22.0 11.5 13.4 22.6 14.2 12.1 13.9 26.3 8.5 17.6 9.9 11.8 11.9 30.2 8.1 9.6 10.3 10.4 10.1 10.4 8.5 16.0 11.4 27.4 15.2 12.0 10.2 7.5 13.0 11.7 13.6 5.1 17.6 16.3 17.4 14.5 11.6 12.9 4.0 6.7 7.7 3.1 3.3 3.7 1.4 19.1 36.9 7.9 22.2 5.6 4.5 18.5 9.9 6.1 16.7 9.4 46.0 11.1 24.8 18.3 8.5 16.8 37.0 18.6 6.8 12.2 29.1 29.7 17.3 23.9 12.7 28.1 17.4 5.5 13.7 19.4 20.9 12.1 37.2 10.3 6.5 34.7 38.1 28.1 29.9 26.2 29.2 8.8 19.8 10.8 26.6 29.0 16.3 17.1 24.1 10.6 30.4 15.6 10.4 8.5 18.5 17.0 24.0 21.5 31.5 35.6 11.0 23.1 14.2 7.7 2.4 0.7 2.5 2.5 3.7 3.6 2.9 2.8 2.0 4.0 2.9 3.6 2.0 3.3 3.1 6.7 2.0 1.4 11.7 14.0 14.6 22.1 14.2 12.1 9.9 11.8 10.4 5.1 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023065 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 73.7;bone marrow: 130.1" "Cell line enhanced" "Detected in some" "A549: 7.1;HEK 293: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 190 "eosinophil: 63.0;neutrophil: 73.7" "Lineage enriched" "Detected in single" 205 "granulocytes: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045702 Enhanced "Secreted to blood" 47000000 "HPA045702: AB_10960204" "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 0.7 0.1 0.2 0.5 0.4 130.1 0.2 0.4 0.2 0.1 0.3 0.3 0.0 0.2 0.1 0.1 0.2 0.4 0.1 10.9 0.2 0.2 0.2 1.5 10.9 1.0 0.2 0.0 0.7 0.2 0.1 1.4 4.1 0.1 0.1 0.1 0.5 0.7 0.1 1.3 0.3 0.2 0.1 0.1 26.9 0.2 0.9 0.0 7.5 1.3 0.0 0.5 0.1 5.5 0.0 0.0 73.7 0.3 0.0 0.0 0.4 0.6 7.1 1.1 0.7 0.0 0.0 1.9 0.6 0.0 0.0 0.0 1.1 0.6 1.9 0.2 0.0 2.6 0.0 0.0 0.0 1.8 4.0 0.8 3.4 0.2 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.5 0.4 2.2 0.4 2.7 1.5 0.2 0.1 0.0 2.6 0.8 0.1 0.5 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.7 1.1 1.5 1.3 0.8 1.1 1.6 0.1 0.0 0.0 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.3 0.0 0.0 0.4 0.2 0.4 0.4 0.2 0.2 0.2 0.2 0.0 0.1 0.0 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 95.8" "Group enriched" "Detected in some" 6 "MCF7: 10.6;T-47d: 10.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.6;monocytes: 7.1;T-cells: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" 160000000000 "Cell Junctions" "CAB033468: AB_1127187, HPA046311: , HPA075237: " "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.6 7.1 0.6 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.6 0.7 0.3 2.6 2.4 2.5 0.3 1.6 1.3 0.2 0.0 3.6 3.7 2.5 0.6 7.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 21.3;skin 1: 39.1;vagina: 10.9" "Group enriched" "Detected in some" 15 "HaCaT: 8.6;HDLM-2: 3.5;hTCEpi: 3.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.5" "Cell type enriched" "Detected in single" 11 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 6.8 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 10.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348840 "Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix, uterine: 8.1;skin 1: 19.5;tongue: 13.7;vagina: 8.5" "Cell line enhanced" "Detected in some" "HaCaT: 8.0;HDLM-2: 5.2;hTCEpi: 1.7;Karpas-707: 4.3" "Group enriched" "Detected in some" 9 "cervical cancer: 2.7;head and neck cancer: 7.8;lung cancer: 1.9;melanoma: 1.6;urothelial cancer: 2.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB025879 Supported "Vesicles,Plasma membrane" "Secreted in other tissues" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 8.1 0.0 0.0 0.0 0.1 2.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.2 0.2 0.0 1.5 0.0 0.1 19.5 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 13.7 6.5 0.0 8.5 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 5.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211997-2214807 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" 46000 "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favourable (6.42e-4)" 5.7 7.2 10.9 7.3 12.5 9.2 3.6 31.4 21.4 3.9 6.7 4.8 7.3 7.9 4.7 6.5 3.6 3.7 4.4 15.6 11.4 9.8 6.1 5.5 6.2 7.5 9.6 12.8 2.5 6.6 8.7 6.1 6.9 17.8 5.3 5.3 4.7 6.2 6.8 40.7 5.6 7.5 4.9 6.0 8.0 6.7 23.0 7.4 5.9 8.8 7.9 5.0 4.2 2.6 1.8 1.9 6.1 3.4 0.3 2.2 0.4 9.1 15.0 10.7 10.1 4.4 3.5 20.5 10.8 5.2 10.0 10.3 23.3 11.6 7.0 10.6 5.0 15.5 7.5 9.2 4.4 9.4 20.8 7.0 22.9 10.5 3.0 12.4 11.6 4.2 4.1 9.3 3.5 6.4 12.7 7.4 5.5 25.0 13.9 20.2 14.1 14.2 22.8 9.3 15.7 8.2 5.8 14.3 8.7 9.6 18.1 7.4 13.4 14.5 6.3 10.3 13.5 9.2 10.7 17.6 7.6 9.9 3.4 11.0 8.0 0.0 2.3 6.1 2.2 3.4 0.3 0.7 1.3 1.6 1.6 1.8 0.8 1.4 1.4 0.3 3.1 1.9 1.3 0.4 10.9 12.5 31.4 21.4 11.4 9.8 9.6 12.8 17.8 7.4 PHKA1 PHKA ENSG00000067177 "Phosphorylase kinase regulatory subunit alpha 1" P46020 X 72578814-72714319 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Muscle protein" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.4" "Cell line enhanced" "Detected in many" "HDLM-2: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001081 Enhanced Approved Vesicles Vesicles "HPA001081: AB_1079607" "unprognostic (3.68e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "prognostic unfavourable (6.84e-4)" "unprognostic (3.52e-1)" "unprognostic (5.48e-2)" "unprognostic (1.23e-2)" "unprognostic (9.64e-2)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "unprognostic (4.76e-1)" "unprognostic (9.45e-3)" "unprognostic (9.94e-2)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" 2.7 10.3 3.8 1.9 7.2 0.7 3.4 3.2 3.5 2.2 2.1 2.0 7.8 1.0 2.7 4.7 4.8 2.8 2.6 5.5 3.0 3.0 2.1 1.8 1.6 1.0 4.2 1.6 5.8 4.2 16.9 14.2 1.8 4.7 4.3 2.5 6.5 6.8 5.1 57.4 2.5 1.3 3.4 3.1 2.3 3.7 3.5 2.7 0.8 6.5 12.6 2.8 3.1 3.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 8.6 12.1 0.7 7.2 4.3 4.1 7.6 1.6 1.5 0.3 0.1 3.5 7.7 0.0 4.8 0.2 3.4 14.4 5.9 0.4 22.0 14.6 4.0 9.9 3.2 4.5 0.0 0.0 5.5 6.0 1.4 9.9 8.4 6.1 0.0 7.9 6.2 6.1 0.4 9.6 16.3 0.0 0.0 0.0 2.1 4.1 7.6 9.0 7.7 10.1 0.1 3.6 0.3 4.3 0.0 3.7 1.5 4.1 10.1 9.3 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.2 3.2 2.9 3.0 3.0 4.2 1.6 4.7 2.7 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892300-18984598 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavourable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favourable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavourable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favourable (2.96e-5)" 9.5 8.6 4.0 9.8 8.3 10.8 7.9 10.9 5.9 8.7 7.7 7.8 4.5 10.1 8.5 5.4 5.8 8.3 10.9 8.6 4.2 3.7 6.2 29.4 5.4 14.1 7.1 3.6 14.5 13.1 8.8 16.9 11.6 6.9 8.3 5.2 9.5 7.4 12.4 6.0 6.9 10.1 4.9 6.6 8.5 6.9 12.4 5.4 29.6 9.2 3.4 9.1 7.2 10.4 3.0 3.2 9.9 5.6 4.2 3.4 2.6 8.5 8.0 4.7 7.7 6.4 6.0 13.1 3.7 3.1 5.5 6.0 8.4 5.5 9.9 2.8 4.8 7.9 8.4 9.6 5.9 5.0 8.8 11.9 12.4 10.1 4.5 11.1 15.4 9.9 6.4 6.6 9.7 5.6 3.9 6.2 3.8 8.7 11.7 18.6 5.7 8.8 9.3 9.7 11.0 3.6 3.8 4.1 6.3 11.4 11.7 5.1 14.5 6.4 10.0 7.5 4.4 8.0 5.7 6.0 5.0 7.6 4.3 6.1 4.0 5.1 4.6 9.9 3.2 5.6 3.4 2.5 2.6 2.3 3.2 3.0 3.2 3.0 8.2 4.2 3.6 1.7 3.2 2.6 4.0 8.3 10.9 5.9 4.2 3.7 7.1 3.6 6.9 5.4 PHKB ENSG00000102893 "Phosphorylase kinase regulatory subunit beta" Q93100 16 47461123-47701523 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073380 Approved "Golgi apparatus" "Golgi apparatus" "HPA073380: " "unprognostic (2.87e-3)" "unprognostic (2.41e-1)" "prognostic favourable (3.69e-4)" "unprognostic (3.98e-2)" "unprognostic (3.98e-2)" "unprognostic (1.28e-2)" "unprognostic (6.73e-2)" "unprognostic (2.99e-2)" "unprognostic (2.35e-3)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (3.01e-2)" "prognostic favourable (3.89e-9)" "unprognostic (3.56e-2)" "unprognostic (1.87e-1)" "prognostic unfavourable (3.24e-4)" "unprognostic (2.53e-2)" 16.9 31.7 11.1 18.1 16.0 11.6 20.6 13.3 16.6 17.2 19.5 16.8 19.5 17.3 22.8 17.6 20.5 12.3 17.0 22.6 11.5 12.4 22.8 16.6 17.0 11.5 14.3 13.0 14.6 21.8 30.0 25.7 17.1 19.9 18.1 19.9 16.1 25.3 21.1 65.6 9.8 24.2 27.0 14.0 17.6 18.5 16.1 10.2 25.2 25.6 23.4 16.3 15.6 15.3 23.1 14.6 12.6 15.6 12.4 11.8 8.7 13.8 20.5 23.7 15.6 16.5 15.8 29.6 16.5 16.1 11.9 6.0 11.2 24.1 16.8 25.0 23.9 19.7 22.1 25.7 16.8 5.2 11.7 16.0 18.4 37.4 14.8 17.2 19.0 14.1 13.1 8.0 15.1 23.1 21.9 10.8 17.1 9.8 16.7 17.0 10.0 15.8 28.7 28.9 28.4 23.8 11.9 12.5 14.2 27.2 36.4 4.4 14.0 14.3 25.5 21.7 10.2 11.0 8.7 12.3 9.0 21.8 13.7 11.7 9.0 7.1 15.0 12.6 9.0 13.4 11.8 23.1 9.5 7.3 14.6 23.1 9.5 9.1 7.8 12.4 15.6 10.0 11.0 8.7 11.1 16.0 13.3 16.6 11.5 12.4 14.3 13.0 19.9 10.2 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.7 3.1 5.3 1.4 0.3 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.5 1.2 0.2 0.8 0.8 2.1 0.8 2.9 0.7 0.8 1.5 3.2 3.3 2.2 1.6 0.7 0.3 2.2 3.9 0.1 1.3 2.2 5.5 1.0 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.1 0.1 1.1 1.9 0.8 0.5 1.7 4.4 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favourable (7.90e-4)" "prognostic unfavourable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favourable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favourable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.5 8.9 7.5 9.2 7.1 5.7 16.9 9.5 14.3 13.0 14.9 7.7 6.8 11.7 11.3 9.8 13.0 7.8 12.1 10.5 6.3 21.7 6.4 14.8 21.6 10.9 9.9 9.2 7.7 6.6 12.5 5.9 13.2 8.7 6.8 9.4 31.2 11.7 14.6 10.3 10.4 15.8 11.7 15.6 14.9 15.3 10.1 7.0 7.7 21.5 9.1 16.9 8.6 7.8 8.0 8.9 10.0 8.7 13.8 7.5 8.0 15.9 19.4 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" "HPA020200: " "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favourable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 8.9 3.4 13.8 4.6 2.3 2.0 10.8 2.7 2.4 5.4 5.5 7.3 5.4 6.0 1.6 4.0 11.0 7.1 4.2 6.9 18.6 5.9 2.0 3.7 13.4 3.3 3.0 1.0 2.1 2.8 5.7 5.3 3.8 5.1 12.2 5.1 2.0 2.2 2.6 5.6 3.3 21.4 7.8 7.2 3.0 11.6 6.4 2.6 2.9 6.7 5.5 2.9 8.8 4.8 4.4 2.1 2.6 6.2 1.4 0.7 7.1 2.6 3.5 3.3 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 29.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048598 Approved Approved Vesicles Vesicles "HPA048598: " "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 6.4 4.7 12.5 7.0 10.9 8.1 8.4 17.4 14.9 4.4 16.6 4.6 4.3 15.8 5.8 4.9 2.7 4.7 4.1 4.6 11.7 9.0 5.4 4.9 4.8 5.0 6.2 14.9 7.2 4.9 10.2 7.3 4.3 12.6 4.7 17.8 13.2 2.9 5.7 5.3 3.0 29.9 7.0 7.6 3.9 4.2 10.8 4.7 1.0 9.9 1.1 4.9 4.7 9.8 2.4 2.2 1.2 0.7 3.5 1.5 0.4 4.8 6.4 7.0 7.8 5.6 6.8 4.0 7.3 6.6 10.6 8.6 5.9 1.6 9.6 2.9 12.0 10.3 10.1 3.7 13.7 3.4 5.5 2.7 5.5 3.8 4.4 2.3 4.2 5.0 2.2 15.0 4.9 3.9 2.4 2.6 7.3 10.2 3.1 1.8 5.5 1.7 5.1 6.2 3.1 5.0 3.7 6.1 3.2 15.7 4.3 2.5 5.3 1.3 5.4 10.7 7.7 4.5 6.0 6.1 4.2 10.0 6.6 1.9 2.3 0.8 0.5 0.2 1.0 0.7 0.9 2.4 0.8 1.5 0.6 1.6 1.1 0.9 1.2 3.5 0.7 2.2 1.3 0.4 12.5 10.9 17.4 14.9 11.7 9.0 6.2 14.9 12.6 4.7 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208497-178232791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria 190000 Mitochondria "HPA036461: AB_10670717, HPA063608: " "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavourable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 18.7 13.1 10.5 25.0 10.8 9.8 15.5 8.3 10.9 13.9 24.3 13.4 14.4 15.1 13.5 14.9 10.7 13.6 17.5 15.5 8.9 4.9 18.1 44.4 14.7 16.8 13.7 9.3 13.2 18.0 11.9 11.9 11.8 10.2 12.4 23.9 12.1 12.3 13.7 20.2 7.6 29.8 14.1 10.7 20.2 15.3 16.4 11.7 16.3 16.6 10.5 17.4 14.0 11.8 13.9 32.8 16.7 21.7 10.7 14.0 14.3 5.7 2.4 5.7 2.3 14.4 11.4 8.6 3.6 4.0 4.8 7.7 6.1 7.3 7.5 10.9 11.0 3.7 4.9 9.2 5.6 15.3 4.9 9.6 9.6 4.3 23.4 5.4 6.1 13.1 9.7 6.0 14.8 16.0 6.9 17.3 7.2 8.4 7.5 2.8 1.1 7.9 5.0 2.7 15.0 8.8 5.2 3.5 3.3 5.7 3.3 6.0 3.6 4.4 6.4 5.0 4.6 3.2 3.8 11.1 3.0 4.5 1.4 5.8 3.3 6.3 19.5 16.7 10.0 21.7 10.1 13.9 11.3 11.4 25.2 12.6 14.0 11.3 4.4 10.7 21.3 32.8 12.9 14.3 10.5 10.8 8.3 10.9 8.9 4.9 13.7 9.3 10.2 11.7 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678935-130746829 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: " "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favourable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 15.5 16.2 11.6 11.6 15.9 10.6 14.9 14.7 17.2 16.5 13.1 14.9 9.5 10.3 18.8 12.0 12.9 15.6 12.0 12.2 9.7 10.0 14.9 28.2 13.7 12.4 12.0 11.4 17.8 12.0 40.7 20.6 14.4 17.3 14.1 11.6 14.1 14.0 15.4 14.8 16.0 13.4 14.6 12.1 18.5 13.3 14.9 11.8 29.7 18.1 10.2 13.6 16.5 13.9 8.4 9.6 12.0 8.5 11.5 13.7 7.0 14.1 9.0 13.2 9.5 19.6 15.6 9.2 10.5 12.7 14.6 16.9 11.6 12.1 16.7 13.3 10.6 20.2 21.7 16.4 23.0 10.0 8.0 13.6 10.3 8.0 9.0 20.6 6.8 10.8 11.8 15.5 9.9 13.4 15.7 8.5 12.8 12.4 16.8 6.3 16.6 8.8 11.8 15.4 15.0 9.6 11.6 12.2 8.9 15.1 9.6 10.6 13.2 9.1 10.6 11.2 9.8 12.6 8.4 9.9 9.0 22.0 12.3 7.9 10.4 12.0 7.2 9.2 9.4 8.4 13.7 8.4 8.6 6.9 9.6 5.7 10.1 9.0 6.0 11.5 8.5 3.4 9.3 7.0 11.6 15.9 14.7 17.2 9.7 10.0 12.0 11.4 17.3 11.8 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 34.8;HMC-1: 64.9;U-698: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.2 2.0 1.1 4.6 2.4 23.5 1.0 3.3 2.2 3.6 4.5 4.2 6.0 1.7 1.2 3.5 2.0 3.2 2.0 27.5 1.3 34.8 1.3 5.8 4.7 0.6 64.9 8.3 4.0 2.0 1.3 0.6 29.9 9.8 0.3 0.7 1.9 3.1 3.7 1.9 4.6 3.6 7.1 0.6 18.4 9.7 1.9 2.3 0.2 0.6 0.5 1.0 1.1 1.3 3.9 5.8 1.3 4.6 2.4 116.6 0.5 8.8 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 5 "HDLM-2: 58.9;Karpas-707: 73.0;RPMI-8226: 71.9;U-266/70: 133.0;U-266/84: 117.5" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favourable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.5 0.8 1.6 0.3 0.2 1.2 1.1 1.4 1.6 1.4 1.4 1.3 7.8 0.5 0.5 1.1 2.6 1.0 1.5 58.9 2.1 9.4 1.6 1.4 0.7 2.2 6.4 0.6 0.9 1.6 1.0 0.5 10.0 73.0 0.9 1.3 0.8 4.7 17.8 2.4 1.0 0.5 71.9 1.6 0.2 0.5 0.8 1.2 0.8 0.8 2.0 3.1 0.3 0.3 0.2 0.3 1.1 133.0 117.5 15.0 1.5 2.0 0.3 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol Cytosol "HPA068758: " "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favourable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.2 4.8 3.2 6.1 2.5 1.9 18.5 4.6 7.4 5.4 3.9 8.0 6.2 12.9 5.8 1.2 6.2 6.2 3.4 1.9 9.7 25.7 5.3 11.5 9.6 12.0 11.5 10.3 3.6 11.5 3.3 5.7 17.6 7.3 45.7 1.6 16.2 5.8 20.6 6.8 7.7 27.2 5.4 15.3 2.9 5.5 11.6 8.1 8.9 40.6 28.4 5.3 15.3 4.6 3.4 14.8 5.6 7.4 23.5 14.9 11.0 8.6 6.5 9.2 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849682 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Approved Enhanced Nucleoplasm,Cytosol 30000 Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: , HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favourable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favourable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 24.5 36.3 40.0 18.7 38.8 25.6 9.3 27.4 66.0 9.2 15.8 18.1 8.5 22.9 14.0 8.3 11.3 16.4 10.1 25.9 38.0 35.2 17.4 14.5 13.2 14.8 38.7 37.2 13.9 21.1 9.5 13.6 13.3 57.3 23.2 6.5 14.1 21.3 15.7 50.2 10.2 21.7 11.1 19.6 15.4 19.6 24.8 15.0 19.7 9.9 8.1 9.3 11.1 9.7 36.4 72.8 88.2 44.9 40.7 53.8 46.2 25.9 23.8 17.8 16.5 6.2 5.6 10.5 19.4 8.4 14.5 14.0 22.1 8.3 16.1 31.0 7.2 13.3 12.2 11.7 4.6 34.3 52.0 41.8 29.3 19.0 10.1 19.5 24.6 7.6 7.9 9.4 4.4 11.8 18.9 24.5 8.7 18.2 29.5 76.2 17.0 36.6 27.0 18.5 27.0 10.4 12.8 22.4 26.4 18.7 9.4 21.7 12.0 23.4 19.9 20.1 16.1 31.1 31.1 31.6 29.7 21.7 21.5 25.0 24.7 52.2 43.4 88.2 42.0 44.9 39.2 35.6 41.5 42.1 39.7 36.4 33.1 37.2 26.8 40.7 41.7 72.8 53.8 46.2 40.0 38.8 27.4 66.0 38.0 35.2 38.7 37.2 57.3 15.0 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA054483: , HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favourable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favourable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favourable (2.66e-4)" 14.4 11.3 15.0 8.0 14.7 6.1 18.8 10.7 16.2 9.7 9.7 8.4 6.7 9.5 11.6 19.3 8.9 8.7 30.7 11.2 15.2 12.2 15.6 23.2 7.9 7.9 12.9 11.0 12.7 8.1 8.0 9.2 9.8 10.0 10.4 11.1 6.6 30.7 37.1 68.7 7.3 9.6 9.2 12.4 16.7 9.3 4.7 6.9 9.7 12.9 40.1 9.1 7.8 9.2 28.9 26.8 23.4 23.6 22.4 33.4 22.7 15.1 17.8 18.6 12.7 12.8 10.7 9.9 10.4 11.9 12.8 13.1 9.0 11.3 4.6 30.4 10.7 10.8 16.5 18.3 15.8 11.5 37.1 7.8 21.2 23.4 7.1 12.3 6.6 7.2 10.1 13.9 4.8 12.9 13.1 20.2 9.5 18.3 10.7 20.7 13.3 16.1 10.7 14.8 13.4 16.2 10.6 11.9 21.3 12.2 5.7 10.7 8.8 11.2 13.0 5.8 8.9 15.9 7.5 6.9 7.5 7.6 16.7 12.3 6.3 21.9 23.3 23.4 26.8 23.6 26.4 28.9 28.3 25.5 22.8 26.4 29.3 29.4 9.7 22.4 21.8 26.8 33.4 22.7 15.0 14.7 10.7 16.2 15.2 12.2 12.9 11.0 10.0 6.9 PINK1 PARK6 ENSG00000158828 "PTEN induced putative kinase 1" Q9BXM7 1 20633455-20651511 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.7" "Group enriched" "Detected in many" 4 "granulocytes: 10.7;monocytes: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Uncertain "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favourable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 17.9 35.9 38.9 6.7 38.0 6.0 10.1 16.8 45.0 9.8 13.0 17.8 10.0 15.2 9.3 9.8 20.7 10.7 11.4 51.4 31.0 28.7 20.2 26.1 10.0 5.1 39.5 27.1 11.6 24.3 16.3 7.1 13.9 31.0 12.4 7.7 10.6 23.9 15.4 142.0 10.8 12.7 10.8 30.2 8.3 10.5 27.2 16.8 3.3 16.0 21.5 4.6 12.7 9.5 1.2 1.4 10.7 4.4 0.7 1.7 0.8 17.9 8.2 3.8 11.0 13.4 12.7 4.0 25.2 25.4 12.3 21.4 2.8 14.6 4.2 20.0 25.7 8.3 5.6 13.4 6.1 5.0 21.2 2.1 22.9 4.4 10.4 2.2 6.7 11.9 14.5 15.3 5.3 7.9 5.1 5.4 8.8 7.6 3.2 5.1 1.7 27.0 2.8 6.8 3.3 7.6 4.2 14.3 5.6 27.5 9.1 7.6 3.0 7.8 12.0 11.1 5.7 18.5 3.5 6.3 1.2 1.9 24.1 6.5 5.2 4.8 2.2 4.7 1.1 1.4 1.4 0.3 1.0 1.5 0.7 1.2 0.8 1.1 10.7 0.7 4.4 1.4 1.7 0.8 38.9 38.0 16.8 45.0 31.0 28.7 39.5 27.1 31.0 16.8 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 98.7" "Cell line enhanced" "Detected in many" "HAP1: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 12.6 9.9 21.6 5.5 35.7 2.6 7.9 13.4 23.7 12.2 5.8 8.9 19.3 4.7 9.2 98.7 5.7 10.2 7.1 7.5 18.4 23.4 7.5 4.4 7.4 5.9 14.9 16.7 16.2 6.0 27.1 12.5 10.7 11.7 9.9 5.3 7.2 6.4 20.3 4.7 7.1 4.4 9.8 12.0 5.9 6.5 13.7 9.5 3.0 13.8 2.9 7.4 7.8 7.9 11.2 4.3 2.7 4.5 14.8 17.8 9.0 10.4 8.0 25.1 17.5 8.8 9.3 7.5 7.0 8.4 6.6 8.9 6.5 9.9 1.6 10.9 11.0 9.1 38.5 13.6 8.3 7.8 13.7 3.1 6.6 4.3 11.0 1.8 6.0 9.7 9.1 11.2 6.7 7.4 2.9 1.1 6.7 5.6 0.8 3.5 17.1 13.1 7.5 11.2 2.5 10.6 8.8 18.6 12.1 11.2 1.9 8.5 3.1 2.6 6.7 5.7 9.2 16.9 3.2 0.0 0.1 3.8 6.2 5.1 7.6 2.7 3.3 1.0 15.5 4.5 17.8 8.7 13.7 14.2 3.6 11.2 14.4 16.6 1.1 14.8 2.9 4.3 8.3 9.0 21.6 35.7 13.4 23.7 18.4 23.4 14.9 16.7 11.7 9.5 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334709-109409994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: " "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavourable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 21.6 27.0 40.1 15.9 49.9 29.0 22.1 41.6 63.0 29.0 23.8 19.7 16.8 12.5 29.2 25.0 20.7 20.3 18.6 24.4 44.3 46.2 24.1 29.2 19.4 14.3 36.8 44.0 35.4 14.8 42.8 30.3 21.8 53.2 31.7 20.6 12.5 17.3 37.7 17.1 13.6 15.9 39.2 37.6 19.5 15.8 17.0 27.4 16.7 35.9 9.7 16.3 35.5 21.4 10.3 11.7 29.9 15.5 10.7 12.2 10.6 11.8 8.2 33.1 25.4 32.9 36.1 18.0 19.4 29.4 15.4 25.3 7.6 16.1 15.2 27.0 37.3 6.9 19.3 24.0 28.3 12.9 7.3 17.5 16.8 10.2 23.3 13.1 26.2 24.8 20.1 20.6 29.6 24.5 12.0 28.7 24.8 7.2 15.7 12.1 6.6 5.5 10.2 29.1 25.3 24.0 10.6 6.3 16.3 20.0 7.3 23.4 16.5 19.4 28.2 21.9 10.7 20.2 9.1 19.4 16.5 18.0 23.2 18.3 14.4 17.3 11.6 17.3 9.5 12.2 9.4 10.3 9.4 8.7 11.7 7.4 12.1 8.9 29.9 10.7 15.5 4.9 12.2 10.6 40.1 49.9 41.6 63.0 44.3 46.2 36.8 44.0 53.2 27.4 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.5;lymphoid tissue: 42.8;testis: 61.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 4.4" "Lineage enriched" "Detected in single" 5 "T-cells: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: " "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavourable (8.33e-4)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 0.9 0.7 0.7 9.4 0.6 19.5 1.3 2.6 0.8 1.3 2.9 0.3 0.5 1.9 0.8 1.5 7.2 0.2 1.5 1.4 0.7 0.7 0.8 1.0 1.3 6.2 0.8 0.2 0.3 1.3 0.0 0.7 4.3 0.4 0.6 0.8 0.3 1.3 0.2 1.6 3.4 3.2 0.6 1.0 4.4 2.7 61.4 0.2 42.8 0.3 9.2 12.7 0.7 2.0 0.8 0.4 0.3 0.5 0.4 4.4 1.0 24.6 17.3 6.8 9.7 0.1 0.3 18.3 19.2 4.6 12.2 11.7 13.4 14.7 15.4 8.6 2.1 31.7 4.7 6.1 2.2 19.8 15.6 7.8 15.6 11.7 0.0 8.7 22.3 0.2 0.5 7.2 1.9 2.5 22.4 27.4 3.9 37.0 24.4 24.2 11.1 9.2 26.6 15.1 29.8 2.3 5.4 12.9 13.6 9.3 24.2 7.2 13.8 17.4 2.3 16.4 20.8 23.9 20.0 20.8 15.4 26.5 6.2 11.7 19.0 0.0 0.4 0.3 0.3 0.3 0.0 0.8 0.5 0.5 0.4 0.0 0.0 0.0 0.1 0.4 0.5 0.1 4.4 1.0 0.7 0.6 2.6 0.8 0.7 0.7 0.8 0.2 0.4 0.2 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.2 22.2 8.3 17.2 13.4 15.8 13.7 13.4 16.1 14.2 13.6 8.6 21.4 35.6 34.8 23.0 8.6 13.2 6.0 5.5 28.8 17.1 42.6 14.2 18.4 44.5 16.7 26.8 11.4 4.3 8.6 13.5 32.9 18.8 24.7 10.4 15.3 25.2 15.5 15.0 25.4 33.9 11.3 25.6 7.0 6.1 30.2 42.8 8.3 10.6 21.7 9.6 29.2 49.2 28.3 12.1 34.1 20.3 32.5 29.6 19.4 18.5 33.6 22.1 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 35.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: , HPA057913: " "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favourable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 21.9 20.7 12.2 21.2 13.7 33.5 27.6 25.6 16.6 28.6 39.3 12.6 15.1 22.9 20.0 20.2 28.2 17.1 13.3 16.2 10.3 8.9 15.9 15.9 26.0 16.4 13.7 8.7 27.2 18.9 24.6 29.7 20.8 13.3 19.6 23.6 14.1 19.5 25.1 15.9 17.5 49.0 17.5 12.5 18.0 15.9 12.4 16.2 29.1 20.3 14.4 13.1 21.9 22.0 4.0 3.7 35.7 4.5 1.4 3.0 1.0 23.3 9.2 18.2 10.9 12.2 13.9 11.8 13.8 12.8 15.6 16.2 9.7 16.8 9.2 16.5 13.1 18.4 17.7 10.5 21.3 3.3 12.9 6.8 19.0 8.3 10.7 6.7 2.0 11.4 11.0 12.2 14.8 17.7 11.3 6.7 16.7 4.7 7.7 5.8 9.1 10.7 7.4 27.7 3.8 13.8 46.0 8.8 5.8 20.7 12.0 17.8 8.9 6.1 16.5 13.2 11.9 16.9 14.4 3.7 3.2 6.3 5.5 6.6 5.0 4.9 4.5 6.8 2.6 2.5 2.3 3.3 2.3 2.4 2.1 4.0 3.0 2.6 35.7 1.4 3.2 3.7 1.8 1.0 12.2 13.7 25.6 16.6 10.3 8.9 13.7 8.7 13.3 16.2 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702523-128720918 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045390, HPA058305" Uncertain Approved Vesicles Vesicles "HPA045390: , HPA058305: " "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 11.4 1.8 1.5 6.8 3.8 3.7 10.5 10.1 3.9 4.3 5.8 3.7 4.8 7.7 9.7 2.2 7.1 5.3 10.9 7.3 2.3 1.7 5.0 6.4 8.9 9.1 3.9 1.2 4.0 4.2 3.3 1.4 5.6 4.5 4.2 1.6 4.1 12.9 3.7 7.4 6.7 5.4 4.9 4.4 7.8 7.4 4.3 1.7 9.3 8.1 6.1 5.9 4.4 5.0 0.4 1.0 2.3 0.7 1.0 1.8 0.3 1.3 6.7 5.5 8.3 0.0 0.1 13.6 4.2 1.3 6.2 6.4 0.0 4.9 0.0 4.1 2.2 9.1 6.7 1.0 1.4 4.2 12.6 8.0 32.8 9.6 1.0 1.0 1.4 0.3 0.3 3.3 0.9 12.2 18.3 0.9 1.1 12.6 1.2 4.3 5.1 2.0 19.9 10.4 1.8 2.6 0.8 0.9 4.1 3.1 1.7 3.1 5.9 6.4 10.5 0.0 5.2 9.7 3.1 3.0 1.3 2.6 0.7 1.0 3.8 0.0 0.1 1.4 0.9 0.7 1.8 0.2 0.6 0.8 1.0 0.4 0.8 0.1 2.3 1.0 0.2 0.2 1.0 0.3 1.5 3.8 10.1 3.9 2.3 1.7 3.9 1.2 4.5 1.7 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 83.9;testis: 32.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "T-reg: 9.0" "Lineage enriched" "Detected in many" 5 "T-cells: 9.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051638, HPA053229" Approved "HPA051638: , HPA053229: " "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavourable (2.70e-7)" "prognostic unfavourable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavourable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 2.9 1.1 1.1 14.2 1.5 15.9 1.7 2.1 1.1 1.5 7.1 0.7 0.5 6.0 1.1 0.9 10.4 0.7 1.5 1.0 1.0 0.8 1.3 1.2 2.6 15.2 0.8 0.6 1.2 0.7 0.0 0.8 6.8 0.7 0.9 5.9 0.5 1.7 0.8 0.8 2.9 5.9 2.0 0.7 8.3 3.6 32.4 0.5 83.9 0.6 6.6 20.4 2.1 2.6 1.9 0.5 0.7 0.1 1.3 9.0 2.3 43.1 45.0 37.2 20.2 1.1 2.6 20.9 24.7 16.3 38.7 28.9 39.3 28.5 21.6 12.9 16.6 24.8 50.7 20.3 46.6 30.7 28.6 27.4 35.5 53.7 0.3 31.6 30.1 1.0 1.1 27.4 28.3 28.3 42.6 29.8 29.8 39.4 29.7 31.6 42.5 22.9 46.5 25.3 34.3 11.0 9.4 21.0 14.6 28.2 19.8 12.8 25.2 19.5 14.3 18.4 23.6 18.0 42.1 21.2 33.0 37.4 15.6 27.5 30.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 1.4 0.5 0.5 0.0 0.0 0.0 0.7 1.3 0.0 0.0 9.0 2.3 1.1 1.5 2.1 1.1 1.0 0.8 0.8 0.6 0.7 0.5 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460260 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 42.9;T-47d: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 11.4 3.7 19.6 4.0 40.2 4.4 23.4 1.3 39.4 20.6 5.7 3.7 5.0 5.1 19.2 7.1 17.7 9.5 18.2 28.1 18.8 5.1 6.9 17.6 17.7 3.8 4.2 20.6 11.8 12.6 3.8 3.3 25.9 8.7 8.7 8.7 12.6 22.1 6.2 8.7 20.9 6.1 15.4 2.7 54.7 4.7 19.8 7.4 1.0 8.9 16.6 7.5 14.2 15.5 1.2 2.9 3.0 1.6 10.4 1.2 0.6 22.9 20.7 7.2 0.5 3.8 6.2 2.8 4.9 8.2 16.3 9.5 1.5 20.3 0.0 32.3 17.6 28.8 0.3 11.3 14.9 0.0 0.6 0.0 9.3 1.7 20.7 0.1 0.6 3.6 15.7 6.3 17.6 32.8 0.0 0.8 32.2 8.3 0.0 0.0 1.3 3.4 1.1 20.0 0.0 42.9 4.6 0.4 0.9 15.1 3.0 13.2 72.3 0.3 41.8 4.5 12.2 2.0 39.1 0.0 0.0 0.0 3.5 0.0 20.0 3.0 0.7 2.3 0.1 1.6 0.0 1.2 0.7 0.0 2.9 0.9 1.2 0.6 1.9 10.4 0.6 2.0 0.5 0.6 19.6 40.2 1.3 39.4 18.8 5.1 4.2 20.6 8.7 7.4 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800225-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced "HPA060318: " "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavourable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 14.8 7.6 4.4 16.3 18.8 8.6 10.0 2.4 6.4 8.6 5.3 13.9 3.2 4.0 9.9 5.8 23.9 8.5 21.6 6.8 10.5 6.0 6.7 9.0 14.9 10.0 9.9 2.5 7.8 10.7 15.6 9.0 29.6 14.8 6.4 4.0 7.6 8.2 6.8 7.0 16.6 7.0 6.0 15.2 9.1 6.1 4.5 5.6 4.6 8.4 25.0 18.2 9.9 9.5 1.3 4.2 2.8 5.1 0.6 11.0 3.5 4.1 2.7 4.2 1.9 3.1 10.2 7.8 9.8 13.8 3.7 3.8 1.6 5.9 5.1 4.1 8.0 3.8 2.3 13.4 2.1 8.2 0.7 5.6 1.5 3.6 15.3 1.8 7.2 7.9 8.0 11.1 10.9 11.7 2.9 2.1 8.4 2.7 3.7 1.6 2.8 3.3 4.4 2.8 7.3 13.3 1.6 3.2 2.0 2.6 4.6 10.8 0.4 1.8 14.9 2.3 5.7 4.5 5.7 5.9 2.7 1.3 4.9 2.9 4.5 0.0 2.9 0.8 1.7 5.0 2.1 1.3 9.9 4.2 4.2 1.1 11.0 4.9 2.8 0.6 5.1 1.8 10.5 3.5 4.4 18.8 2.4 6.4 10.5 6.0 9.9 2.5 14.8 5.6 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880861-127899195 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5;lymphoid tissue: 21.7;testis: 21.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol "Centrosome, Cytosol" "HPA017327: , HPA035026: AB_10602080, HPA043198: " "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favourable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavourable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.4 1.3 1.5 4.7 2.4 16.5 2.2 0.5 2.2 2.0 3.2 0.3 0.6 2.3 1.3 1.3 5.4 1.1 1.2 2.0 1.2 1.3 1.5 0.9 1.5 5.9 1.2 1.4 1.5 0.9 0.3 0.6 5.0 2.6 1.4 3.7 0.8 1.7 0.7 0.4 2.7 3.2 1.9 1.8 2.7 1.6 21.7 1.0 21.7 1.0 2.1 6.0 1.5 2.2 0.7 0.7 1.5 0.8 1.4 4.0 0.8 11.6 5.5 20.7 10.6 0.7 2.0 9.4 11.4 8.1 15.2 15.8 7.7 12.0 15.7 4.2 6.3 7.7 14.6 9.1 23.5 12.2 6.0 14.2 8.8 7.2 0.2 20.0 16.9 0.6 0.9 13.9 6.4 11.7 16.5 21.0 12.8 8.1 30.8 9.0 9.6 6.3 16.1 14.5 5.4 5.0 7.4 11.5 9.4 7.2 6.6 3.5 5.3 8.7 5.0 12.0 11.6 8.1 14.2 10.9 11.9 22.4 6.1 15.3 13.2 0.0 0.4 1.5 1.6 0.8 1.1 0.3 1.8 1.7 0.7 0.7 0.6 2.3 0.0 1.4 0.3 0.4 4.0 0.8 1.5 2.4 0.5 2.2 1.2 1.3 1.2 1.4 2.6 1.0 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" 2700000 Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavourable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavourable (2.43e-4)" 29.0 19.5 14.9 16.8 24.0 7.1 32.1 12.1 17.6 35.8 21.7 17.0 17.7 19.1 34.2 21.1 16.5 24.7 21.3 31.2 17.6 14.8 27.5 51.3 22.2 19.7 24.5 9.9 31.8 30.3 18.2 16.3 41.5 20.8 21.1 12.0 25.1 39.3 22.0 18.3 13.3 20.8 39.0 13.2 21.1 18.6 10.0 22.4 1.7 34.8 11.1 8.2 19.5 69.7 1.6 16.3 17.7 19.4 2.6 9.1 9.3 17.6 15.1 8.3 38.9 56.9 31.9 6.7 52.5 69.7 27.7 47.1 17.2 11.6 10.2 55.5 57.9 14.9 12.1 18.3 19.1 10.6 12.9 5.5 24.3 21.8 35.3 3.4 26.8 38.7 9.6 33.4 13.4 49.0 15.4 5.0 28.8 11.4 0.8 9.2 3.7 22.5 4.1 16.9 22.1 15.9 4.0 3.2 13.2 22.9 15.7 26.4 7.9 8.8 48.4 31.7 23.8 39.6 25.7 11.7 19.1 6.1 70.2 12.1 51.6 0.0 19.4 0.9 9.1 17.2 1.6 1.0 1.6 4.4 16.3 1.6 0.6 3.4 17.7 2.6 15.0 2.4 1.0 9.3 14.9 24.0 12.1 17.6 17.6 14.8 24.5 9.9 20.8 22.4 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 85.3;U-87 MG: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavourable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavourable (7.64e-10)" "prognostic unfavourable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavourable (4.99e-11)" "prognostic unfavourable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 36.7 14.1 11.2 18.0 12.1 0.7 28.5 7.9 13.5 8.8 25.2 5.1 8.3 21.6 14.8 7.5 12.0 8.0 22.3 16.6 12.5 8.2 16.4 73.1 9.3 3.0 10.7 4.8 17.7 14.4 13.9 7.8 41.0 13.0 11.1 16.1 7.2 7.7 11.3 4.8 3.2 24.7 24.2 19.4 3.2 13.6 6.3 10.9 6.1 47.6 3.5 3.0 21.8 28.7 0.0 0.0 1.5 0.3 0.0 0.0 1.9 17.0 12.2 3.8 1.2 13.9 15.0 9.7 60.4 18.5 32.9 62.1 0.9 1.7 0.0 11.8 10.2 3.6 4.4 51.9 85.3 0.0 7.0 4.2 11.9 8.4 35.8 0.0 0.0 26.2 7.5 28.5 13.9 45.4 5.6 0.2 58.1 6.2 0.0 0.0 2.4 5.2 0.0 2.5 0.0 13.8 0.8 1.9 0.0 48.1 5.2 5.1 14.1 0.5 57.0 40.8 12.4 12.9 36.0 18.5 2.6 0.0 76.0 0.0 7.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 11.2 12.1 7.9 13.5 12.5 8.2 10.7 4.8 13.0 10.9 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 103.6;WM-115: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 13.4;monocytes: 14.3;T-cells: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted - unknown location" 370000 "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavourable (1.91e-5)" "prognostic unfavourable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 23.9 16.1 11.9 19.5 24.0 14.6 35.4 7.2 19.2 17.8 20.0 31.2 16.6 22.7 22.9 15.1 11.0 17.4 16.7 22.1 14.8 11.6 20.2 54.1 21.0 18.2 36.3 8.9 16.1 23.2 18.5 16.5 33.1 22.4 14.4 14.2 11.1 11.3 19.6 8.8 14.0 23.2 23.2 29.0 20.4 16.7 10.1 30.6 5.1 16.8 6.0 6.9 17.3 42.6 2.6 13.4 2.8 14.3 2.5 9.2 5.3 9.9 9.0 3.8 25.2 18.1 13.0 7.7 18.3 20.6 18.8 13.6 14.4 12.9 0.8 20.6 31.6 12.1 7.6 10.7 4.8 5.4 3.4 1.0 10.9 14.1 24.9 4.5 8.5 14.0 10.3 11.0 8.7 16.7 9.6 103.6 12.6 28.4 0.4 10.7 8.0 13.7 3.1 5.1 15.4 6.4 2.9 2.9 17.1 11.4 16.7 40.8 3.1 15.5 14.5 28.5 13.9 34.5 22.5 5.8 10.6 0.6 16.9 10.9 99.9 0.0 10.8 2.8 9.2 14.3 8.1 2.6 6.8 6.1 10.4 1.8 3.2 3.4 1.0 2.5 14.3 13.4 4.3 5.3 11.9 24.0 7.2 19.2 14.8 11.6 36.3 8.9 22.4 30.6 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell line enriched" "Detected in some" 8 "AN3-CA: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 26.5 0.0 0.0 2.8 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.1 0.0 0.1 2.1 0.2 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favourable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 12.8 8.7 8.8 13.8 8.4 6.5 14.3 20.8 10.6 9.6 8.4 6.9 16.9 8.3 6.6 6.3 10.5 3.1 11.7 5.7 10.7 13.3 14.1 16.4 6.0 6.3 13.3 19.0 6.1 6.2 8.7 5.7 12.6 6.9 16.8 12.5 8.2 13.5 10.7 8.2 17.7 11.5 8.1 16.8 9.9 27.5 10.4 16.8 9.1 27.4 4.6 4.7 8.3 17.8 18.8 11.5 4.5 17.1 18.6 7.5 6.7 17.0 6.0 14.9 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavourable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 12.8 48.2 7.4 7.5 10.8 3.6 15.0 5.3 16.4 11.0 20.8 9.6 32.1 24.9 9.0 8.2 13.4 12.8 9.9 8.4 7.1 7.2 12.0 78.4 13.7 9.9 5.2 10.1 14.4 12.8 12.1 18.5 18.6 7.1 9.3 5.3 10.8 7.8 58.7 13.1 10.0 24.3 7.0 5.2 11.7 9.8 22.4 5.0 8.2 33.3 9.9 8.6 9.8 10.2 5.7 20.6 26.7 18.4 11.2 9.9 13.9 12.7 27.9 12.8 23.7 48.5 18.4 21.4 5.3 17.5 10.1 14.1 20.9 56.7 12.2 4.9 11.6 6.2 16.8 8.4 4.3 10.4 12.4 5.6 8.2 38.7 33.7 5.6 10.1 37.8 10.6 13.3 9.7 9.4 16.9 5.3 9.1 18.7 6.1 10.1 15.9 15.8 8.7 8.4 13.1 11.4 15.4 13.4 12.8 14.4 73.3 19.3 21.0 9.6 8.4 9.5 10.5 14.3 10.5 5.2 8.0 8.3 13.4 8.6 12.2 26.7 18.4 25.3 9.9 17.7 8.3 5.4 8.4 9.2 20.6 5.7 8.4 7.1 24.3 11.2 13.0 5.8 8.7 13.9 7.4 10.8 5.3 16.4 7.1 7.2 5.2 10.1 7.1 5.0 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 12.1;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;granulocytes: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm Nucleoplasm "CAB075701: , HPA058901: , HPA067049: " "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favourable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 5.7 6.6 5.8 6.0 6.2 4.2 6.9 2.6 4.5 3.8 11.8 5.9 9.9 13.9 4.8 6.6 6.3 3.9 9.1 19.6 5.1 4.1 17.8 30.9 3.8 3.4 6.1 4.9 9.1 13.4 6.6 3.5 3.1 7.8 6.2 7.1 13.5 8.1 8.2 17.1 5.8 19.7 5.0 4.7 3.5 5.7 2.7 7.1 1.3 5.4 10.4 4.8 7.3 12.3 1.5 3.8 12.1 1.4 0.9 1.5 0.3 6.8 1.7 2.1 7.6 12.1 7.8 4.8 5.9 11.9 6.4 6.6 3.3 3.3 2.4 3.0 13.8 3.1 6.4 7.8 5.8 7.0 8.1 7.6 4.3 7.0 7.6 5.1 13.0 6.1 6.3 4.7 10.9 1.3 2.7 5.7 5.9 1.7 5.8 1.9 0.3 1.7 6.9 7.8 3.2 4.4 4.0 2.1 6.4 2.3 2.1 7.5 2.4 4.0 2.3 6.7 7.2 6.0 2.6 5.7 3.3 1.0 10.5 5.8 2.0 1.7 1.0 12.1 1.4 1.4 1.2 1.0 0.7 0.7 0.7 1.5 0.8 0.6 0.8 0.9 0.8 3.8 1.5 0.3 5.8 6.2 2.6 4.5 5.1 4.1 6.1 4.9 7.8 7.1 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;testis: 20.2" "Cell line enhanced" "Detected in some" "A549: 3.5;HeLa: 5.1;SH-SY5Y: 2.9;SK-MEL-30: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.5 3.1 0.2 6.4 1.4 3.9 0.2 10.6 0.2 0.2 0.1 0.0 0.1 0.3 0.9 0.2 0.2 0.3 0.3 1.9 1.0 0.3 0.1 0.4 0.3 1.7 6.9 0.2 0.2 0.1 0.7 1.0 0.2 0.5 0.1 0.0 0.3 0.6 0.1 0.7 0.1 0.2 10.5 0.3 0.1 20.2 0.0 0.1 0.4 0.0 0.3 0.4 0.1 0.2 1.3 0.0 0.9 0.0 0.0 0.2 0.0 3.5 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 1.2 0.0 5.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.1 6.4 0.2 10.6 1.9 1.0 1.7 6.9 0.2 0.0 PPEF2 PPP7CB ENSG00000156194 "Protein phosphatase with EF-hand domain 2" O14830 4 75859864-75902571 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 75.7" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (3.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (1.53e-1)" "unprognostic (9.02e-2)" "unprognostic (3.32e-4)" "unprognostic (2.74e-2)" "unprognostic (4.54e-8)" "unprognostic (2.89e-1)" "unprognostic (5.98e-2)" "unprognostic (5.16e-1)" "unprognostic (3.66e-3)" 0.1 0.0 0.0 0.2 0.4 0.2 0.3 3.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 75.7 0.0 0.0 0.3 0.4 0.1 0.1 0.1 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 3.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" 420000000 "CAB004655: AB_425607, HPA058345: " "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavourable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 92.0 90.3 147.0 80.4 124.3 105.9 169.0 88.9 148.0 111.3 143.5 81.6 52.9 73.9 74.8 125.1 176.5 76.3 80.4 60.2 132.0 121.9 149.2 214.3 95.4 137.1 123.2 88.3 74.2 103.2 93.1 58.3 96.2 142.5 83.0 149.1 68.1 84.7 102.3 68.4 114.7 105.1 113.9 120.8 137.0 73.1 62.4 59.8 228.2 130.2 123.4 191.2 94.3 93.1 129.8 158.5 35.0 83.1 76.0 117.7 180.3 85.8 115.3 146.5 106.3 122.8 186.7 48.3 125.9 197.8 241.9 237.4 127.9 131.7 194.2 64.9 160.3 117.5 188.3 241.1 223.2 111.0 137.3 78.4 132.9 121.8 99.6 158.9 81.9 136.6 165.6 171.4 188.4 245.6 161.1 157.1 248.7 122.3 174.1 281.4 167.2 159.0 125.1 88.7 247.0 328.0 121.5 109.7 90.9 106.1 304.4 82.7 163.2 217.0 109.1 124.7 120.3 83.4 165.0 114.7 226.4 327.7 108.7 180.9 188.0 23.4 74.5 35.0 94.9 83.1 102.0 129.8 97.0 97.1 134.8 103.9 80.3 88.2 9.2 76.0 77.7 158.5 117.7 180.3 147.0 124.3 88.9 148.0 132.0 121.9 123.2 88.3 142.5 59.8 PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889746-120890405 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 3.5;intestine: 1.6" "Cell line enhanced" "Detected in many" "NB-4: 4.5;SK-BR-3: 4.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (3.49e-3)" "unprognostic (2.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-2)" "unprognostic (1.74e-1)" 0.3 0.8 1.0 1.4 0.2 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 3.0 3.2 0.6 1.6 2.2 2.4 3.5 0.9 0.0 0.1 1.4 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 1.0 0.7 0.2 0.0 1.7 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.8 0.0 0.0 0.3 0.2 3.7 0.3 0.6 1.7 4.5 2.4 0.0 0.8 1.5 1.9 0.0 0.0 1.0 0.3 0.3 4.6 0.4 3.0 2.5 0.7 3.0 1.2 2.9 1.6 1.3 0.9 2.4 2.6 1.5 3.1 0.2 1.6 0.6 1.4 1.2 1.4 3.0 2.3 2.4 3.1 2.2 1.5 2.4 0.0 2.2 1.2 3.2 2.4 3.5 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 10.9;intestine: 5.5" "Cell line enhanced" "Detected in many" "NB-4: 14.2;THP-1: 16.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA058345 Uncertain "HPA058345: " "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.0 3.3 2.7 0.1 0.0 1.5 0.0 0.8 5.5 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 2.9 0.2 0.0 0.9 0.7 0.3 0.0 0.0 0.0 0.2 0.5 2.9 0.0 1.4 0.9 0.0 0.0 0.3 0.0 9.1 9.7 1.9 6.0 4.6 7.8 10.9 3.5 0.3 0.4 3.1 0.1 0.3 2.0 0.5 0.4 1.0 0.7 0.0 4.8 1.2 2.1 0.0 3.9 0.0 0.2 0.6 3.5 0.0 0.5 0.0 0.0 0.1 2.0 1.9 0.1 0.5 0.6 0.3 0.0 0.9 5.3 0.7 0.4 5.2 14.2 6.1 0.1 5.2 0.0 8.9 0.2 0.0 3.9 5.4 1.1 11.1 6.0 5.2 16.6 1.2 3.5 5.5 3.3 8.0 4.2 5.5 9.0 3.8 4.6 7.7 0.9 4.3 1.9 5.4 6.0 6.0 9.1 6.1 5.7 9.4 7.2 5.0 5.9 0.0 4.6 5.3 9.7 7.8 10.9 PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373659 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 3.4;bone marrow: 2.7;skeletal muscle: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;HL-60: 1.3;NB-4: 1.4;SK-BR-3: 2.1;TIME: 2.0" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (6.97e-2)" "unprognostic (5.22e-2)" "unprognostic (2.28e-1)" 0.0 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.9 2.0 3.4 2.9 0.6 0.6 0.5 0.5 0.1 0.0 0.0 0.4 0.2 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 2.0 0.1 0.6 0.3 0.0 0.6 0.4 0.2 0.0 0.2 0.0 0.0 2.0 1.0 2.9 0.5 1.9 1.3 1.6 1.3 0.5 1.7 0.5 0.5 1.9 3.4 1.5 0.6 0.8 0.6 PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148479824-148483679 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 6.9;skeletal muscle: 6.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (2.17e-3)" "unprognostic (3.63e-1)" "unprognostic (4.83e-1)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" 0.2 0.1 1.3 0.7 1.8 1.3 0.3 6.9 1.2 0.1 0.2 0.5 0.4 1.0 0.3 0.1 0.3 0.2 0.9 1.1 0.1 0.2 0.2 1.1 0.5 0.4 0.0 0.1 0.3 0.1 0.2 0.3 0.4 0.0 6.8 0.8 0.7 0.0 0.4 2.7 0.5 0.5 0.4 0.3 0.0 0.0 2.2 0.6 2.4 0.8 2.4 3.2 0.2 0.8 1.1 0.5 1.7 0.2 0.3 1.3 0.3 0.3 0.1 0.1 1.3 0.9 1.2 0.8 0.3 1.0 0.1 0.2 0.2 0.5 0.6 1.2 2.4 1.0 0.1 1.5 1.1 0.2 1.8 0.1 0.3 0.2 0.7 1.8 0.0 0.9 0.8 2.5 1.1 0.3 0.6 0.3 0.8 0.3 1.3 0.7 0.9 1.0 0.7 0.4 1.1 1.3 0.8 0.9 0.9 1.4 0.7 1.4 1.2 1.0 0.7 1.0 0.9 2.2 0.4 1.0 3.2 0.4 2.4 0.9 1.5 1.7 0.3 2.2 1.6 2.8 2.4 2.4 0.8 0.6 0.5 0.2 PPIB "CYPB, OI9" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155812-64163205 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Isomerase, Rotamase" "Disease mutation, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" 120000000 "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favourable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavourable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 56.9 64.3 23.9 49.3 26.9 54.9 48.1 15.1 32.1 75.3 44.1 35.4 102.8 42.0 64.2 106.9 48.0 54.8 58.1 44.5 23.8 27.3 89.5 285.9 57.2 63.8 29.7 19.6 67.5 193.7 26.7 71.8 120.2 27.5 51.0 47.7 36.2 123.3 95.4 19.5 33.1 57.5 54.3 30.7 78.0 47.7 27.2 29.5 53.7 154.3 45.7 69.1 49.2 51.7 63.5 191.6 41.0 51.1 44.9 71.6 87.1 39.3 49.5 44.7 101.6 156.7 91.0 39.3 94.0 123.5 74.4 88.5 71.2 73.1 37.6 76.4 145.5 64.2 81.7 63.1 38.4 23.8 30.8 53.0 54.7 93.1 164.3 52.9 48.0 83.8 68.1 43.4 105.8 89.8 37.0 131.0 56.4 62.8 16.1 81.1 39.0 31.8 30.9 47.5 191.8 77.2 61.4 25.3 39.9 43.0 74.0 68.4 44.2 161.8 55.2 74.4 61.7 41.6 63.4 71.2 68.9 39.5 69.5 85.2 74.2 41.0 51.1 33.9 71.6 39.2 71.5 63.5 50.5 58.1 67.4 38.0 33.0 44.2 25.5 44.9 25.2 191.6 40.1 87.1 23.9 26.9 15.1 32.1 23.8 27.3 29.7 19.6 27.5 29.5 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" 5700000 "HPA039163: " "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavourable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 22.5 13.7 3.3 10.8 3.6 0.0 29.9 1.6 4.2 24.3 30.0 3.6 26.6 15.7 20.4 32.7 35.5 9.0 25.8 43.7 4.0 2.7 27.4 24.0 16.3 9.0 3.7 2.1 13.3 24.3 8.7 5.8 28.3 10.0 17.8 22.0 5.3 25.9 18.0 18.4 12.0 35.2 37.9 5.4 8.9 13.5 8.0 3.2 2.5 42.7 29.6 12.9 31.5 21.5 0.0 1.1 0.0 0.1 0.0 0.3 0.0 4.6 4.1 1.6 33.8 58.8 27.0 6.7 13.3 10.4 6.9 14.3 6.8 31.7 0.0 23.7 35.8 5.3 4.6 16.8 5.6 0.0 8.1 6.7 15.4 7.8 15.1 0.0 3.7 16.9 12.9 8.1 8.6 14.3 1.8 0.0 4.9 27.8 0.0 0.0 2.9 7.1 0.0 3.6 0.0 21.9 16.3 2.1 3.7 26.1 12.7 2.8 17.8 14.9 15.8 13.4 8.4 4.6 5.7 0.0 0.0 0.0 11.6 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 3.3 3.6 1.6 4.2 4.0 2.7 3.7 2.1 10.0 3.2 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709134-158723396 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoli, Cytosol" Nucleoplasm "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 16.8 25.8 20.1 15.5 21.4 14.9 22.3 26.7 26.8 12.6 16.8 14.4 18.2 33.4 14.6 13.6 16.5 15.4 13.0 28.8 19.4 22.1 21.5 45.3 11.0 17.4 22.6 18.9 14.6 17.5 11.3 30.3 14.5 26.0 16.1 14.2 9.1 15.4 13.7 53.3 24.0 29.2 13.1 22.7 16.5 15.5 16.9 23.4 22.7 21.7 16.0 16.8 15.4 55.0 15.6 17.2 33.4 22.2 23.9 24.4 17.1 15.3 14.3 14.4 19.7 21.4 16.1 21.8 15.2 8.3 14.0 10.6 18.5 10.5 16.2 6.8 14.1 11.8 43.6 17.4 17.1 53.7 15.2 29.0 12.9 25.5 16.6 18.2 21.8 10.1 14.2 12.0 17.9 15.2 36.2 29.0 15.5 14.7 26.0 16.5 19.8 19.1 11.8 7.1 13.9 15.4 7.7 24.4 16.3 11.4 23.7 21.6 10.9 17.4 14.7 14.0 15.8 15.4 20.0 16.7 34.6 20.7 17.8 19.7 14.0 33.4 15.3 33.2 21.2 22.2 24.4 14.6 20.7 19.6 16.7 15.6 21.5 22.0 20.9 23.9 22.0 17.2 22.4 17.1 20.1 21.4 26.7 26.8 19.4 22.1 22.6 18.9 26.0 23.4 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA019357: , HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavourable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavourable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 19.3 23.8 23.7 24.3 22.5 18.6 25.7 25.9 36.1 25.5 28.1 35.6 22.2 19.7 30.6 26.5 26.0 34.7 21.1 27.1 22.3 22.1 25.2 29.8 20.6 25.9 26.3 20.5 35.5 42.1 27.4 23.6 21.9 24.9 26.1 22.7 26.9 30.7 28.9 29.6 21.7 23.2 34.2 25.6 25.7 23.9 38.8 20.2 22.8 33.7 21.9 33.9 31.5 22.6 43.3 31.6 14.1 27.2 49.0 46.9 44.2 9.6 16.7 15.4 12.3 17.1 15.2 8.1 16.6 16.7 25.4 23.9 20.8 28.5 27.4 23.5 18.6 14.7 21.0 24.7 24.3 17.7 22.6 30.2 19.4 6.3 23.5 27.2 16.6 13.8 22.6 23.8 8.8 22.8 30.6 19.2 18.5 17.3 12.5 22.1 18.4 18.7 18.6 11.6 15.6 19.2 18.0 21.9 17.5 17.4 14.2 12.0 17.8 71.5 14.8 16.0 17.7 19.7 25.5 26.3 26.3 18.9 11.1 35.1 25.0 11.6 27.1 14.1 38.3 27.0 37.0 43.3 39.7 38.2 31.6 39.8 46.9 38.9 2.2 49.0 27.2 28.5 40.0 44.2 23.7 22.5 25.9 36.1 22.3 22.1 26.3 20.5 24.9 20.2 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 32.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria 27000000 Mitochondria "HPA077416: " "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 16.5 76.2 12.1 15.7 18.8 52.0 16.9 7.1 21.3 8.3 18.1 27.1 13.2 13.3 5.2 7.6 21.0 8.8 10.0 36.5 13.0 14.5 21.0 73.1 9.4 19.4 23.3 16.6 7.2 42.0 12.0 6.2 11.3 25.2 6.6 19.9 7.5 12.7 21.9 44.4 22.5 11.1 9.9 28.0 19.6 34.0 20.8 18.0 8.8 10.0 73.9 19.8 12.5 11.0 8.0 18.6 32.8 14.9 3.6 5.0 6.5 35.1 15.0 10.5 20.7 9.8 12.8 13.5 20.5 27.0 45.2 42.8 35.0 17.1 36.6 11.4 14.4 21.1 32.6 19.1 70.5 11.6 30.7 57.3 14.7 61.6 16.7 39.4 13.6 30.0 13.8 44.8 44.9 7.9 55.7 45.2 15.3 18.1 10.2 33.0 8.8 83.4 17.6 16.3 18.7 17.5 32.9 21.0 15.6 10.5 42.7 15.8 18.7 30.5 7.1 19.8 18.0 23.3 39.5 21.0 21.3 29.6 19.6 51.4 5.3 5.1 14.9 7.3 4.7 11.4 5.0 8.0 4.2 4.3 18.6 3.9 3.8 3.7 32.8 3.6 4.1 2.3 4.2 6.5 12.1 18.8 7.1 21.3 13.0 14.5 23.3 16.6 25.2 18.0 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584340-169641406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: " "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavourable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.2 25.3 28.5 23.8 45.3 39.2 26.7 45.0 40.7 33.1 27.1 14.6 26.0 25.3 27.1 28.1 29.4 24.3 21.2 24.2 30.0 20.3 26.0 41.1 25.5 30.4 27.7 35.9 29.5 22.8 39.4 56.7 26.0 38.0 29.3 23.9 13.8 28.6 28.8 27.8 24.5 30.8 31.9 39.7 29.7 24.1 19.8 33.7 24.1 28.4 22.6 29.9 37.4 27.6 36.4 23.7 41.7 24.7 18.7 29.6 13.3 19.1 9.1 25.8 14.1 14.3 17.6 24.3 21.9 16.5 16.2 16.8 24.9 22.1 33.1 20.2 15.8 18.5 20.2 18.0 24.0 23.0 16.3 49.8 13.6 30.3 13.8 46.8 22.2 14.8 20.4 22.0 24.7 17.8 48.0 27.6 18.5 15.5 34.5 28.7 37.0 9.3 31.8 25.8 32.3 20.1 28.9 22.6 14.9 23.6 17.6 23.8 16.4 27.1 20.4 21.2 16.2 14.1 18.0 16.1 23.1 46.2 15.6 25.1 19.4 20.7 20.0 29.9 20.3 20.1 23.2 27.6 27.0 23.8 14.9 36.4 29.6 23.7 41.7 18.7 24.7 23.7 22.9 13.3 28.5 45.3 45.0 40.7 30.0 20.3 27.7 35.9 38.0 33.7 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658425-42676758 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved "HPA059019: " "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavourable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavourable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 17.5 19.7 20.4 35.7 19.6 40.7 21.4 23.9 23.3 19.5 24.0 20.9 14.7 18.0 29.8 24.2 29.6 19.2 14.4 21.2 18.0 16.1 17.5 13.6 17.8 31.0 15.8 19.9 22.0 17.7 7.0 15.2 24.6 17.2 17.1 26.5 19.2 24.4 18.8 18.4 20.9 20.7 20.8 15.0 27.2 18.0 21.1 18.6 39.7 26.9 28.1 36.8 15.3 20.3 20.0 14.9 16.8 12.3 18.5 26.3 14.0 18.9 12.2 15.5 21.7 5.1 9.7 20.9 12.9 9.2 24.2 22.2 19.3 21.7 31.4 16.3 9.6 15.5 28.2 19.8 25.5 26.4 22.7 29.8 22.6 17.9 4.4 57.1 17.5 6.3 10.5 22.6 17.6 11.2 36.9 17.9 11.9 15.9 44.3 80.5 38.1 14.7 24.8 28.9 27.9 11.6 12.4 12.2 22.1 11.4 18.9 14.2 10.4 83.7 9.3 10.7 27.4 14.6 30.9 11.6 26.9 57.1 11.9 53.5 17.5 12.6 8.8 16.8 21.0 12.3 19.8 20.0 21.7 23.9 11.7 19.2 22.3 26.3 1.8 18.5 11.2 14.9 20.2 14.0 20.4 19.6 23.9 23.3 18.0 16.1 15.8 19.9 17.2 18.6 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36875024 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Approved Nucleoli Nucleoli "HPA062916: " "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavourable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favourable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 9.0 17.2 15.9 11.1 23.1 7.3 12.3 16.6 18.7 11.1 10.2 13.0 5.7 8.7 13.7 11.7 13.1 17.5 7.5 29.7 13.2 19.8 17.6 34.3 7.5 13.4 15.0 15.5 13.2 36.7 10.6 19.4 16.0 15.3 11.2 13.2 11.0 12.0 12.5 11.7 5.6 8.2 17.4 15.8 10.3 8.5 14.0 11.0 10.2 23.5 13.4 17.4 12.2 8.1 7.7 6.6 1.1 4.4 5.0 15.0 6.9 14.1 11.2 29.6 19.7 4.0 8.4 16.0 14.4 9.6 21.7 18.1 19.6 9.4 21.7 18.3 10.1 11.5 35.0 24.0 24.9 18.1 29.2 25.8 7.3 25.9 13.2 22.0 10.8 6.3 11.4 16.7 31.3 19.4 48.3 10.6 15.7 13.4 26.1 10.1 19.6 15.2 21.1 25.9 19.5 12.9 10.0 31.5 16.6 9.6 10.3 18.9 15.0 18.7 11.8 16.8 15.5 12.8 24.0 11.6 30.3 39.7 5.3 40.8 31.9 1.1 3.2 0.8 11.2 4.4 15.0 7.7 9.3 10.7 6.6 6.2 10.5 12.3 0.9 5.0 2.1 5.6 6.8 6.9 15.9 23.1 16.6 18.7 13.2 19.8 15.0 15.5 15.3 11.0 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666009-21700015 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm Nucleoplasm "HPA035344: AB_10672863, HPA055637: " "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 15.0 21.5 19.4 20.9 24.6 16.6 13.5 24.1 30.9 17.7 17.4 25.3 19.1 18.6 21.8 17.0 22.3 15.7 16.5 20.0 17.2 17.1 21.2 20.3 14.6 23.7 15.6 20.9 16.6 31.4 23.6 30.2 31.4 19.0 19.5 17.6 23.6 22.0 16.5 25.5 17.5 19.1 15.2 15.0 21.3 19.5 18.4 17.6 32.8 27.0 13.6 33.5 17.4 16.2 8.7 11.7 4.8 17.3 12.8 13.2 9.1 6.5 6.8 8.0 8.4 8.1 7.0 7.2 8.6 6.1 10.5 9.0 6.9 4.3 11.2 5.2 9.5 9.6 10.6 7.3 6.3 6.9 10.8 10.5 6.8 8.1 5.9 16.5 9.9 7.5 6.6 7.5 5.7 9.0 69.7 8.1 7.5 10.2 7.4 4.5 7.6 4.2 9.6 11.8 2.3 5.3 6.6 12.4 6.8 7.8 12.4 2.8 8.9 5.5 10.9 6.6 10.7 7.7 5.4 9.4 6.8 8.5 7.5 6.3 7.9 1.0 8.6 4.7 9.5 13.9 11.4 7.0 11.1 12.0 11.7 8.7 9.8 8.9 4.8 12.8 17.3 11.1 13.2 9.1 19.4 24.6 24.1 30.9 17.2 17.1 15.6 20.9 19.0 17.6 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Supported Nucleoplasm 35000 Nucleoplasm "HPA040765: , HPA062187: " "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favourable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 12.4 17.9 18.1 15.5 19.2 24.2 21.1 20.1 20.2 19.4 16.4 18.4 21.1 12.7 17.2 24.3 25.4 19.1 15.9 17.6 17.5 21.8 15.9 19.4 15.9 23.7 20.0 11.8 31.4 16.7 11.9 17.4 15.5 23.0 19.5 16.6 16.3 13.8 15.8 13.4 14.7 15.7 16.8 23.2 20.2 15.7 18.2 13.0 26.3 23.7 19.4 25.5 28.6 13.6 23.4 21.7 18.7 14.1 20.6 20.6 10.7 7.9 7.1 22.0 9.5 17.3 37.1 7.2 12.8 13.8 14.7 14.9 5.2 15.2 7.6 13.5 13.7 10.5 7.6 15.5 13.2 16.2 18.5 32.4 19.9 35.0 8.9 31.0 16.5 13.4 15.3 12.0 19.1 9.8 25.6 18.8 18.8 12.7 23.8 24.7 13.4 11.4 9.0 12.3 12.1 19.4 12.4 9.1 8.5 12.9 12.2 20.5 10.2 14.1 13.3 21.3 12.0 12.6 10.5 20.6 19.5 36.1 16.2 13.9 13.4 18.7 12.7 12.7 12.7 10.8 18.5 23.4 15.6 13.7 21.7 18.9 19.1 20.6 3.0 20.6 14.1 17.9 20.1 10.7 18.1 19.2 20.1 20.2 17.5 21.8 20.0 11.8 23.0 13.0 PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504733-149546038 "Enzymes, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm Nucleoplasm "HPA031599: AB_2673950, HPA031600: AB_10600928" "unprognostic (6.12e-2)" "unprognostic (4.90e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (7.53e-2)" "unprognostic (6.36e-3)" "unprognostic (2.91e-3)" "unprognostic (2.22e-1)" "unprognostic (4.22e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.62e-2)" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.94e-2)" 20.0 20.1 20.6 15.0 35.5 30.6 21.2 35.1 27.8 24.0 15.3 19.7 10.1 14.1 21.1 27.2 15.7 18.0 19.8 18.3 21.3 15.6 18.8 23.0 17.9 15.7 20.9 18.0 32.9 16.0 20.8 36.6 22.6 23.9 20.5 16.8 15.7 18.2 16.7 14.8 15.4 16.0 20.0 22.7 17.6 16.0 15.9 19.4 27.0 26.8 8.2 16.8 22.0 19.2 21.4 16.6 24.9 17.8 28.7 24.6 14.8 10.9 5.9 20.7 17.1 12.3 16.2 19.3 21.7 20.7 23.7 25.4 12.4 11.3 11.6 15.0 16.7 10.0 15.8 8.3 37.7 16.8 14.9 12.8 13.0 21.3 19.4 23.3 10.9 12.6 14.2 24.2 20.3 12.9 27.8 7.0 18.4 11.7 13.2 20.0 16.3 9.3 17.9 19.1 5.8 18.0 8.4 12.2 9.4 25.8 11.3 14.7 13.3 17.0 15.1 15.7 12.4 27.8 20.6 9.3 4.7 18.2 13.3 18.7 22.7 24.9 16.1 18.1 14.7 17.8 20.4 21.4 19.5 16.9 16.6 16.6 24.6 18.7 13.4 28.7 16.1 16.2 20.7 14.8 20.6 35.5 35.1 27.8 21.3 15.6 20.9 18.0 23.9 19.4 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.5" "Cell line enhanced" "Detected in many" "AN3-CA: 6.6;ASC diff: 10.6;ASC TERT1: 13.2;hTCEpi: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.5 1.4 5.5 1.1 8.6 0.7 3.6 5.0 4.8 4.6 1.7 7.2 7.4 1.9 3.8 12.7 2.0 36.5 1.7 2.6 6.0 5.4 4.9 1.2 8.9 1.1 3.4 3.2 6.3 4.3 6.6 7.6 1.6 18.3 1.8 1.6 2.6 2.8 5.0 3.9 1.7 1.1 5.4 3.2 1.3 2.3 20.4 5.3 0.0 17.2 1.4 1.1 2.9 2.0 5.1 1.7 2.0 1.3 1.7 1.3 1.1 1.8 1.1 1.2 6.6 10.6 13.2 1.2 0.0 2.4 0.6 0.2 0.1 1.8 0.0 0.5 0.6 1.2 1.0 0.0 0.4 0.5 0.9 0.5 0.1 0.0 5.3 0.6 0.3 2.7 6.3 0.2 4.0 0.8 0.9 0.4 0.4 0.6 0.1 0.6 0.2 1.3 0.8 0.0 0.6 5.1 0.1 1.5 2.5 0.2 0.3 4.4 0.5 1.0 0.4 0.1 0.2 1.1 0.2 0.3 0.1 0.1 2.2 0.1 0.4 2.0 1.2 1.2 0.9 1.3 0.9 5.1 1.2 1.1 1.7 3.2 1.1 1.0 1.6 1.7 1.1 1.7 1.3 1.1 5.5 8.6 5.0 4.8 6.0 5.4 3.4 3.2 18.3 5.3 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" 850000 Cytosol "Plasma membrane" "HPA029209: " "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favourable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 16.2 11.7 13.8 15.0 18.3 64.0 15.1 20.5 28.6 15.5 32.4 13.3 9.4 19.1 17.4 12.7 15.2 10.7 10.8 37.1 13.5 16.1 22.8 26.7 14.6 11.8 15.6 19.1 12.1 13.3 18.2 12.2 15.8 24.3 16.5 19.4 12.3 18.7 13.5 56.1 16.7 25.2 15.0 13.8 11.6 14.9 29.7 12.7 23.4 13.3 11.6 13.4 15.2 16.5 4.0 2.7 8.0 2.1 4.7 4.5 1.9 47.8 10.8 9.4 8.0 14.4 13.4 12.0 13.2 15.5 9.8 9.3 6.1 14.1 28.8 12.6 14.9 10.7 9.7 13.6 17.2 25.9 5.5 17.7 7.7 9.5 12.1 20.0 12.7 11.3 16.3 11.5 15.8 9.6 9.8 23.0 11.9 21.0 26.0 4.7 8.8 9.1 9.4 21.8 9.3 11.8 23.0 16.0 12.0 13.7 16.0 11.1 16.1 8.8 13.2 20.5 20.5 8.9 9.3 17.9 10.1 33.7 9.4 7.9 10.3 6.7 1.8 5.1 3.5 1.8 3.8 1.7 2.8 3.1 2.7 4.0 2.2 2.1 8.0 4.7 2.1 1.6 4.5 1.9 13.8 18.3 20.5 28.6 13.5 16.1 15.6 19.1 24.3 12.7 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 23.7 13.8 31.2 12.2 33.8 24.7 15.2 32.6 25.2 16.3 18.2 26.0 13.6 13.2 15.7 20.4 14.9 12.7 14.3 21.1 29.6 24.6 19.4 27.7 13.4 16.6 34.6 22.4 15.8 20.9 34.6 17.9 12.1 22.9 20.7 19.0 24.3 16.4 16.4 72.0 12.5 14.3 21.1 27.3 16.1 14.8 13.3 34.1 19.1 15.0 13.1 16.8 18.2 15.9 6.5 5.5 11.1 5.0 4.7 9.5 1.6 17.3 15.5 20.7 15.1 25.9 12.1 23.5 13.5 15.6 14.0 12.4 20.9 11.3 19.1 21.2 15.5 9.5 23.1 8.8 20.8 19.3 9.0 20.2 9.3 14.3 20.9 18.0 16.9 11.6 15.5 11.1 18.9 11.4 14.7 20.3 12.5 14.4 17.8 29.0 25.5 5.2 19.0 23.1 12.8 32.6 17.6 16.7 21.0 12.1 18.2 15.6 9.8 12.6 10.4 12.3 17.7 10.1 12.9 17.8 11.6 17.9 6.5 30.0 8.8 8.3 3.3 11.1 7.2 4.5 6.2 5.8 6.9 6.1 5.5 6.5 9.5 6.4 9.2 4.7 5.0 5.3 6.2 1.6 31.2 33.8 32.6 24.9 29.6 24.6 34.6 22.4 22.9 34.1 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022277 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA022277: AB_1858839" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favourable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 12.2 7.0 6.1 5.7 9.2 13.6 11.9 30.8 6.6 11.1 10.0 10.6 7.8 7.6 12.0 8.3 8.6 11.1 8.3 5.8 7.7 4.4 7.4 7.4 9.2 7.9 10.3 4.6 17.3 12.3 8.1 8.9 18.5 8.8 9.3 9.4 8.2 8.1 6.8 9.7 8.1 8.1 8.2 7.3 9.2 7.3 16.2 12.5 15.5 8.7 6.9 7.0 7.8 11.3 7.3 13.1 20.5 13.2 6.8 8.3 6.8 2.7 5.4 6.1 5.2 4.1 2.5 7.9 4.3 2.8 2.8 4.0 5.5 1.6 7.8 3.5 2.9 2.9 3.9 1.8 3.8 1.4 8.7 5.6 5.4 6.4 3.4 2.2 4.3 2.2 2.9 4.1 2.4 6.3 4.1 3.3 3.0 26.5 6.1 3.4 2.6 4.2 7.4 7.8 4.7 2.5 3.4 8.4 6.1 5.7 1.9 1.3 2.3 3.0 4.6 3.6 10.0 2.8 2.3 5.3 5.6 5.9 1.4 2.3 2.8 8.2 13.2 14.1 6.7 10.2 5.9 7.3 5.6 6.1 13.1 5.9 6.1 6.2 20.5 6.8 6.1 5.8 8.3 6.8 6.1 9.2 30.8 6.6 7.7 4.4 10.3 4.6 8.8 12.5 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755869-58985176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 10.7;brain: 36.5;testis: 13.1" "Cell line enhanced" "Detected in some" "AF22: 10.0;HAP1: 16.2;MOLT-4: 7.6;SCLC-21H: 7.5;SH-SY5Y: 15.5;THP-1: 6.9" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 2.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.7 10.7 15.0 0.8 7.5 0.7 0.7 11.9 23.3 1.0 0.7 3.6 0.0 0.8 1.1 2.2 0.7 3.3 0.8 2.3 36.5 5.4 1.9 2.4 1.0 0.9 3.2 9.2 1.0 1.7 0.8 3.4 0.6 10.5 3.2 0.7 3.5 0.8 0.7 0.6 0.7 1.0 1.3 2.7 0.8 1.4 13.1 2.0 0.0 0.8 0.0 1.0 0.6 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.5 0.0 0.0 0.7 0.0 0.0 0.8 1.1 0.0 0.0 6.3 0.1 0.1 0.0 16.2 0.0 0.4 0.1 4.8 0.0 0.1 0.0 1.1 0.5 2.1 0.3 1.3 0.0 0.0 0.0 1.6 0.0 0.0 2.8 7.6 0.0 2.8 0.8 0.0 1.3 0.0 0.0 0.0 7.5 15.5 0.2 0.0 1.0 0.0 6.9 0.0 0.0 1.9 0.0 2.3 0.0 0.1 4.3 0.2 0.0 2.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 7.5 11.9 14.0 36.5 5.4 3.2 9.2 10.5 2.0 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919420-21952837 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.7" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.7;monocytes: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" 780000 Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavourable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 25.0 15.6 14.0 21.8 14.3 24.3 18.4 16.9 16.3 18.1 13.2 7.6 12.5 9.6 17.6 9.7 23.6 12.3 13.1 17.0 13.9 14.9 13.2 8.5 21.6 15.1 11.6 10.1 14.4 10.7 8.3 7.7 28.1 14.5 15.6 4.9 11.2 11.2 16.5 15.8 15.5 11.1 15.4 15.5 31.4 10.5 6.7 10.9 6.2 10.9 15.1 10.2 15.8 37.6 0.7 5.5 17.7 13.9 1.7 1.4 2.8 9.1 9.8 6.3 6.1 3.5 6.2 7.9 10.4 6.2 9.2 6.3 4.4 3.7 5.5 13.0 7.3 11.0 2.7 6.4 3.3 7.8 8.8 21.3 4.5 4.2 5.8 7.8 5.8 5.8 1.9 9.0 4.2 35.8 54.2 2.3 11.8 8.4 4.6 6.1 2.6 10.7 7.0 16.2 1.6 3.1 3.9 2.5 9.8 9.9 3.3 8.5 4.1 5.5 30.1 11.1 11.3 10.1 9.9 4.6 3.7 6.1 11.2 15.0 21.2 0.0 7.7 3.3 1.0 12.9 0.7 0.7 0.7 0.6 5.5 0.6 0.7 0.8 17.7 1.7 13.9 1.4 1.4 2.8 14.0 14.3 16.9 16.3 13.9 14.9 11.6 10.1 14.5 10.9 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381194-27409687 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavourable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favourable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 12.7 17.0 9.9 19.9 9.2 19.4 30.2 10.9 19.3 17.9 14.6 9.1 16.9 12.1 26.8 12.5 19.4 19.2 17.7 13.6 8.8 7.6 12.6 18.6 14.7 20.2 9.4 8.0 13.4 18.6 13.8 13.2 11.4 8.7 10.2 16.4 9.1 16.4 18.7 24.1 10.9 12.2 14.9 6.7 14.7 14.1 93.3 8.4 25.8 14.1 19.1 22.5 25.2 17.3 20.2 40.3 24.5 29.1 22.7 38.3 19.0 50.1 41.4 30.4 23.4 19.4 15.8 28.1 31.3 20.6 37.6 30.2 63.7 26.6 59.2 23.0 22.2 27.5 51.1 35.2 33.8 24.7 41.5 57.6 30.2 67.3 17.5 56.9 24.4 17.1 20.4 38.3 30.9 35.9 48.2 18.4 28.5 44.9 42.2 61.7 44.2 29.9 43.7 63.7 31.1 25.3 35.0 40.9 46.3 28.1 31.1 22.4 17.2 18.7 28.8 28.2 34.1 24.6 47.4 40.2 45.0 93.6 22.0 46.6 21.1 22.1 17.8 24.5 26.9 22.3 26.5 20.2 28.7 27.9 28.5 18.0 21.7 22.4 9.1 22.7 29.1 40.3 38.3 19.0 9.9 9.2 10.9 19.3 8.8 7.6 9.4 8.0 8.7 8.4 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.1" "Cell line enhanced" "Detected in many" "Daudi: 27.1;Karpas-707: 23.6;U-698: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 3.6 6.1 19.2 8.8 17.2 5.9 9.3 21.1 26.8 12.9 3.8 12.5 2.5 3.0 21.8 5.5 7.6 14.1 6.0 59.1 23.1 14.6 11.8 5.1 6.5 14.5 21.6 15.9 22.0 7.3 10.4 8.4 6.4 17.0 11.1 4.3 4.7 7.1 5.3 8.3 1.9 6.7 18.2 15.0 10.9 5.4 12.3 19.4 7.3 5.4 1.9 15.8 6.5 8.1 31.8 38.8 5.5 3.4 7.9 16.1 7.1 2.1 0.7 2.8 4.9 4.2 5.5 1.1 3.4 6.3 11.6 13.7 5.6 0.5 27.1 3.8 2.2 0.2 8.2 2.6 4.6 20.9 3.4 4.8 2.1 5.0 3.3 6.6 2.6 3.6 1.3 7.1 6.2 1.9 7.2 23.6 3.3 3.1 8.7 3.6 1.7 1.1 5.0 4.6 10.3 4.0 0.9 2.2 1.9 2.1 0.2 2.5 11.2 1.8 0.3 4.0 2.1 1.3 2.0 7.4 6.8 22.7 4.4 5.4 6.7 5.5 2.9 2.3 12.4 3.4 16.1 30.4 11.8 12.4 5.5 31.8 11.7 14.1 0.9 7.9 0.9 38.8 13.3 7.1 19.2 17.2 21.1 26.8 23.1 14.6 21.6 15.9 17.0 19.4 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245793-52250597 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.0;U-266/70: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: " "unprognostic (4.26e-3)" "prognostic favourable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favourable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 14.3 7.2 13.9 22.7 14.8 16.5 26.3 3.6 9.2 16.9 12.5 4.6 7.8 4.4 13.6 12.0 10.8 11.7 19.4 14.5 8.7 8.5 8.7 4.9 30.1 38.0 5.4 12.3 14.9 5.9 6.9 7.5 8.6 4.9 15.1 6.7 11.0 10.8 12.4 3.1 7.5 8.8 18.1 6.8 22.5 8.3 6.2 5.9 20.5 11.3 9.9 20.5 11.3 13.5 5.0 9.6 19.6 18.6 7.4 15.0 10.1 0.4 2.5 1.6 3.7 22.9 23.0 2.5 5.8 12.6 8.3 6.4 1.5 2.0 4.2 1.7 15.2 0.7 5.2 1.1 3.4 5.1 1.2 9.6 6.7 1.5 16.8 1.4 9.2 18.9 2.5 9.2 5.8 10.6 1.6 7.0 9.6 1.0 6.3 0.4 2.0 7.1 1.4 0.7 9.3 3.6 1.1 1.1 4.6 4.2 1.1 5.2 3.6 3.7 7.4 3.1 5.3 1.8 0.7 26.3 4.9 4.5 6.3 2.5 3.8 1.2 15.7 8.5 15.0 12.4 11.7 5.0 11.8 13.8 9.6 3.8 11.1 13.8 19.6 7.4 18.6 5.8 13.2 10.1 13.9 14.8 3.6 9.2 8.7 8.5 5.4 12.3 4.9 5.9 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398183-67421183 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 177.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 8100000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: " "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favourable (1.17e-4)" "unprognostic (7.60e-2)" 28.4 35.4 24.2 42.0 32.3 42.1 25.1 19.6 33.4 23.9 39.6 22.1 29.9 33.9 19.6 25.8 59.7 22.8 28.6 33.0 21.8 17.1 43.7 55.0 27.6 49.3 19.9 19.9 20.1 53.3 23.1 21.6 44.0 19.3 27.2 33.2 23.2 49.7 31.1 39.0 34.4 47.3 20.5 21.3 53.7 35.1 15.7 19.4 77.7 38.5 40.5 63.9 25.5 25.7 78.8 76.6 126.2 118.0 68.2 113.9 177.2 46.2 53.4 31.7 46.6 15.8 19.4 32.3 22.9 26.9 46.3 35.2 76.3 55.9 39.8 39.1 34.8 40.5 36.6 47.7 28.5 41.8 24.8 38.2 25.2 40.0 34.5 48.5 49.4 21.8 31.6 39.4 23.2 46.4 35.5 33.0 37.4 105.5 61.5 95.4 52.5 42.3 43.7 43.9 34.5 45.4 38.3 24.8 41.2 26.6 47.8 70.7 57.2 33.6 33.0 35.7 36.6 42.1 29.6 33.1 30.6 45.2 42.8 33.4 37.6 81.4 80.1 126.2 88.6 100.5 69.3 78.8 79.8 90.5 76.6 77.0 49.1 69.2 93.3 68.2 118.0 54.4 113.9 177.2 24.2 32.3 19.6 33.4 21.8 17.1 19.9 19.9 19.3 19.4 PPP1CB "PP-1B, PP1B, PP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 7700000 "Nucleoplasm, Plasma membrane" Cytosol "CAB022558: , CAB069426: , HPA065425: " "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 28.5 22.6 30.0 20.5 37.6 29.5 32.4 19.1 29.8 51.1 39.3 21.1 30.7 24.4 58.0 31.8 86.0 37.0 33.3 67.1 27.8 27.9 32.0 20.0 35.3 22.3 27.4 24.4 39.7 21.9 48.9 28.7 42.3 22.0 46.4 27.7 25.2 36.5 38.6 99.6 25.1 30.0 100.8 27.5 25.2 31.4 25.5 21.4 28.1 27.5 32.9 25.3 82.1 50.5 15.6 25.4 41.5 42.7 23.5 28.3 17.9 36.4 23.0 80.2 24.8 27.5 25.6 46.7 19.6 22.4 19.1 18.9 20.4 21.6 29.2 24.7 20.3 22.6 22.8 26.2 22.8 46.3 11.8 22.0 28.2 22.0 59.9 24.9 10.4 19.6 37.3 20.6 43.2 23.1 20.0 29.0 25.0 18.3 26.4 21.6 26.3 18.2 26.0 71.1 22.2 62.2 44.1 22.0 27.2 30.5 33.9 26.6 16.4 14.0 27.6 25.6 28.2 18.3 23.6 20.7 32.5 59.8 27.2 26.9 18.9 22.5 24.8 32.1 16.8 37.8 21.3 15.6 25.5 19.6 25.4 13.4 22.7 25.5 41.5 23.5 42.7 19.6 28.3 17.9 30.0 37.6 19.1 29.8 27.8 27.9 27.4 24.4 22.0 21.4 PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022645 Uncertain 7600000 "CAB022645: " "unprognostic (1.51e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.29e-2)" "unprognostic (7.26e-2)" "prognostic unfavourable (2.75e-6)" "unprognostic (6.55e-2)" "unprognostic (4.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.92e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" 23.3 29.4 27.4 23.4 29.8 28.8 24.1 31.9 32.3 25.2 63.3 22.2 15.4 63.0 25.9 19.8 31.3 22.9 21.5 66.5 29.4 21.0 19.8 20.6 19.6 41.4 32.0 21.9 31.7 38.8 19.6 25.8 17.0 25.9 26.1 36.4 28.7 26.9 19.4 63.4 24.0 73.3 46.3 25.9 27.1 25.2 43.7 28.3 42.3 25.9 18.3 41.3 37.9 23.2 17.8 19.1 30.8 19.1 8.5 14.9 12.5 45.0 27.2 46.6 34.0 28.3 39.1 35.6 26.0 38.8 43.3 34.7 46.4 23.0 70.5 19.7 27.9 25.8 62.4 34.2 60.6 40.9 42.0 45.6 20.4 47.3 23.1 58.0 39.7 24.6 28.0 32.7 29.3 50.0 45.4 19.1 39.6 18.7 46.9 65.1 73.3 40.2 46.2 32.2 44.6 27.7 34.3 37.6 30.2 28.7 34.6 50.1 54.1 45.4 22.2 22.2 36.6 29.8 32.6 30.2 31.3 60.4 20.8 42.2 33.6 18.7 19.1 30.8 8.2 14.9 8.0 17.8 14.9 11.7 19.1 15.4 12.4 10.2 16.3 8.5 18.8 7.4 13.7 12.5 27.4 29.8 31.9 32.3 29.4 21.0 32.0 21.9 25.9 28.3 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.0;skeletal muscle: 227.2" "Group enriched" "Detected in some" 4 "ASC diff: 6.4;NTERA-2: 20.8;RPTEC TERT1: 22.9" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB007811, HPA041542" Approved "CAB007811: AB_598171, HPA041542: " "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavourable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 67.0 2.1 9.9 1.6 33.2 1.3 51.8 2.2 8.2 1.6 4.0 2.9 0.5 2.2 1.7 1.8 4.3 1.6 1.9 34.6 6.6 3.7 35.4 27.5 1.3 1.4 6.4 4.8 3.3 5.6 3.9 0.1 1.2 4.8 2.9 1.8 0.1 3.1 2.3 227.2 1.3 2.4 2.3 2.7 1.3 4.7 1.7 7.8 0.0 1.4 16.6 1.4 1.4 4.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.8 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 33.2 2.2 8.2 6.6 3.7 6.4 4.8 4.8 7.8 PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 173.9;salivary gland: 105.3" "Cell line enhanced" "Detected in some" "ASC diff: 5.5;CAPAN-2: 8.7;HSkMC: 23.1;SCLC-21H: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "basal ganglia: 173.9" "Cell type enriched" "Detected in single" 37 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.6" "Region enriched" "Detected in many" 8 "basal ganglia: 1113.7" "Region enriched" "Detected in all" 21 "basal ganglia: 1698.9" "CAB004026, HPA048630, HPA061142" Approved Approved "CAB004026: AB_2169007, HPA048630: , HPA061142: " "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" 26.2 10.0 25.6 5.8 173.9 0.6 23.3 14.6 24.1 7.4 64.1 16.2 39.4 25.7 1.8 2.2 1.9 9.4 4.6 0.7 17.3 11.2 2.0 0.5 5.1 0.5 21.9 22.2 2.6 19.1 0.6 1.7 0.5 17.9 19.9 63.3 6.9 105.3 49.6 0.5 5.7 20.9 4.1 12.4 0.5 13.6 4.6 40.0 0.0 0.5 0.3 0.8 3.6 1.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 3.3 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.6 0.0 0.0 0.4 0.0 0.0 19.3 0.4 0.0 1.0 0.0 0.4 0.7 0.0 0.0 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 173.9 14.6 24.1 17.3 11.2 21.9 22.2 17.9 40.0 PPP1R2 "IPP2, PPP1R2A" ENSG00000184203 "Protein phosphatase 1 regulatory inhibitor subunit 2" P41236 3 195514425-195543386 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 66.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA043729, HPA059420" Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA043729: , HPA059420: " "unprognostic (1.85e-2)" "unprognostic (3.71e-3)" "unprognostic (6.26e-2)" "unprognostic (3.58e-1)" "unprognostic (5.66e-2)" "unprognostic (1.44e-1)" "unprognostic (4.17e-2)" "unprognostic (3.92e-1)" "unprognostic (4.20e-2)" "unprognostic (2.00e-1)" "unprognostic (6.73e-2)" "unprognostic (8.32e-2)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (3.74e-1)" "unprognostic (2.71e-1)" "unprognostic (2.13e-1)" 16.4 12.7 19.9 17.7 26.0 45.2 18.3 16.2 22.9 16.1 21.2 11.4 17.4 19.5 18.9 20.7 25.6 15.3 15.8 23.3 18.6 21.7 16.7 13.0 21.7 30.4 16.5 15.4 17.1 12.0 9.5 17.6 16.1 21.2 17.0 16.0 13.7 15.0 19.0 57.1 14.1 22.6 17.7 15.4 24.2 13.9 21.8 7.0 38.1 19.1 25.2 23.5 26.5 15.5 26.0 26.6 63.2 16.9 22.8 50.2 30.1 11.4 2.5 4.2 4.8 7.1 7.7 7.7 7.1 10.4 7.6 6.6 38.6 5.1 4.5 28.6 8.7 5.1 4.4 7.2 9.4 8.9 8.3 5.1 4.2 12.9 11.0 5.4 5.4 9.3 5.6 5.7 11.6 6.5 3.9 9.7 6.7 8.0 9.6 6.0 4.4 11.6 4.5 7.4 13.4 9.1 8.7 10.0 5.5 8.6 9.5 12.8 15.0 5.5 7.2 4.9 5.7 8.0 9.7 66.1 28.7 21.7 6.9 9.9 9.5 26.3 16.7 63.2 19.6 16.9 26.9 26.0 41.2 27.0 17.6 23.6 50.2 34.0 39.4 22.8 16.4 26.6 41.7 30.1 19.9 26.0 16.2 22.9 18.6 21.7 16.5 15.4 21.2 7.0 PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "heart muscle: 24.1;skeletal muscle: 69.4;tongue: 75.4" "Cell line enriched" "Detected in single" 64 "THP-1: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 19 "thalamus: 1.2" "Low region specificity" "Detected in some" "HPA070440, HPA073138" Enhanced "HPA070440: , HPA073138: " "unprognostic (8.96e-3)" 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.7 0.0 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 1.4 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 75.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633054 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 259.9" "Cell line enhanced" "Detected in many" "HeLa: 17.3;HHSteC: 21.9;LHCN-M2: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027041 Uncertain "HPA027041: AB_1855649" "unprognostic (2.11e-1)" "unprognostic (1.86e-3)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.15e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.38e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-3)" "unprognostic (5.63e-3)" "unprognostic (1.59e-2)" "unprognostic (5.48e-3)" "unprognostic (8.44e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" 4.0 5.4 10.4 2.8 18.9 1.5 3.5 1.1 15.8 24.9 4.1 8.0 8.3 2.7 7.1 6.5 26.5 4.5 6.0 53.3 13.1 5.7 5.4 39.5 5.4 1.8 6.1 8.1 6.6 5.6 2.8 1.7 6.3 12.2 11.0 2.8 4.5 10.0 13.4 259.9 4.4 2.2 14.8 9.1 2.2 5.2 2.2 6.1 0.0 2.4 28.2 7.7 11.4 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.7 10.9 5.0 2.4 0.0 12.1 9.4 4.9 5.3 0.0 0.9 0.0 0.5 11.2 0.6 0.2 1.3 9.2 0.0 0.0 0.1 17.3 1.9 21.9 0.0 0.0 8.1 2.1 3.1 0.2 1.2 5.6 0.0 41.9 0.4 0.0 0.0 0.7 0.0 0.0 2.6 0.0 0.4 10.5 0.3 0.7 0.0 0.0 0.0 0.0 1.8 8.2 2.2 2.2 2.9 1.7 0.0 0.2 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 18.9 1.1 15.8 13.1 5.7 6.1 8.1 12.2 6.1 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194334-134226142 "Enzymes, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved "CAB003848: AB_562203, HPA043236: " "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavourable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 26.0 30.5 37.6 22.0 41.0 57.9 26.0 54.2 56.6 23.0 27.3 29.6 15.6 24.8 29.8 20.4 39.6 21.9 24.7 47.9 39.8 38.1 31.7 33.2 22.7 29.1 35.0 35.8 23.4 23.9 44.5 20.6 44.0 47.5 22.3 26.4 18.4 23.6 23.7 43.1 32.6 26.5 31.6 32.8 30.4 21.8 18.8 24.1 45.6 33.2 30.5 39.9 26.9 24.5 29.2 41.1 39.0 33.4 38.9 37.5 43.8 38.3 32.2 46.1 24.8 24.1 25.9 32.4 36.2 31.1 55.2 55.8 61.9 30.1 33.6 34.1 33.4 20.0 44.3 52.3 64.7 30.4 25.3 23.8 37.8 38.4 35.7 23.5 21.6 24.0 36.3 43.2 43.1 38.7 23.4 25.2 41.8 27.5 37.2 23.0 25.2 19.5 33.4 45.9 32.6 33.2 43.2 36.8 25.7 37.3 14.0 40.5 28.5 27.8 27.2 31.9 18.0 25.5 51.0 22.7 40.6 53.1 21.5 31.2 32.9 20.3 33.4 39.0 26.7 33.0 34.1 29.2 30.7 35.6 41.1 28.6 35.7 32.7 38.7 38.9 33.3 22.0 37.5 43.8 37.6 41.0 54.2 56.6 39.8 38.1 35.0 35.8 47.5 24.1 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm Nucleoplasm "CAB018600: AB_675841, HPA043236: " "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favourable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 26.7 21.0 61.3 11.9 54.9 2.6 28.7 32.0 46.2 28.8 24.1 30.7 19.4 21.7 34.5 37.5 29.7 28.2 23.1 27.2 57.3 43.7 41.0 35.7 27.7 8.4 52.6 39.8 48.0 22.9 33.7 14.8 27.4 47.7 23.7 24.5 12.5 19.5 29.1 27.4 18.0 31.2 39.0 49.7 15.0 18.9 18.8 48.2 6.3 44.5 14.0 14.0 17.7 34.3 5.8 7.9 5.1 6.5 7.3 4.8 1.7 22.0 19.2 33.7 12.9 33.7 30.7 18.8 29.5 27.6 30.7 32.1 20.2 16.2 10.7 29.0 39.3 13.3 20.0 33.9 41.3 6.7 10.6 14.4 13.1 20.3 38.7 6.4 8.2 27.1 38.8 25.9 29.0 36.6 22.1 11.4 51.6 10.8 17.4 8.2 24.6 11.1 12.2 13.6 8.0 41.0 17.8 32.4 13.4 13.6 14.5 28.4 7.9 11.0 38.5 26.5 19.9 8.7 24.3 5.9 7.6 12.7 22.6 5.9 33.8 4.8 5.0 3.3 4.2 6.5 4.8 5.8 3.8 4.2 3.5 2.7 3.8 4.6 5.1 7.3 3.0 7.9 2.8 1.7 61.3 54.9 32.0 46.2 57.3 43.7 52.6 39.8 47.7 48.2 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190039-52229533 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol 3400000 Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavourable (1.76e-4)" "prognostic unfavourable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favourable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 25.3 57.3 60.7 20.5 71.0 18.0 21.4 47.5 82.1 29.6 31.2 26.6 21.5 33.4 26.4 37.9 37.7 47.0 39.9 74.7 70.2 44.8 31.0 29.3 20.0 27.5 44.0 50.9 45.8 24.3 37.8 29.5 24.6 51.0 31.0 29.8 31.0 24.3 35.6 50.6 33.5 25.3 34.5 25.2 20.5 19.8 21.7 18.1 29.0 28.9 35.9 30.6 27.3 23.1 52.8 62.8 51.9 67.2 69.8 56.3 67.8 30.4 51.7 41.3 36.7 33.6 35.2 21.7 25.7 33.7 34.4 30.0 26.0 24.1 26.7 18.5 40.8 22.0 44.2 38.7 20.0 19.7 119.9 19.6 28.5 29.2 30.7 21.1 18.7 47.2 32.1 32.1 29.6 32.6 22.7 18.8 38.0 35.2 29.5 40.3 40.9 45.7 29.0 24.0 29.8 55.2 50.2 31.2 33.4 31.4 31.4 19.1 28.4 37.3 30.9 27.3 24.6 13.3 29.3 19.5 28.5 31.3 29.3 21.4 34.3 45.0 55.3 51.9 50.4 67.2 45.8 48.4 45.1 47.1 62.8 52.8 37.7 43.0 33.7 69.8 59.8 39.0 56.3 67.8 60.7 71.0 47.5 82.1 70.2 44.8 44.0 50.9 51.0 18.1 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.9" "Cell line enhanced" "Detected in all" "U-698: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" Cytosol "Nucleoplasm, Plasma membrane, Centrosome" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favourable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 31.6 7.2 7.1 7.6 9.8 7.7 13.5 14.8 7.1 7.9 8.2 13.6 5.7 7.7 6.3 5.6 7.9 5.0 7.8 4.6 7.4 5.0 10.3 94.9 5.4 6.2 12.6 3.4 8.7 18.5 5.4 19.4 6.7 9.8 4.6 8.5 6.6 8.8 4.0 6.2 6.7 9.4 5.9 8.7 4.2 11.9 28.6 13.9 10.1 6.1 7.2 9.4 6.0 5.1 11.5 14.7 9.9 11.9 14.1 14.3 12.0 12.8 8.6 12.4 8.4 12.5 6.8 12.5 12.7 8.9 9.5 8.7 29.2 13.5 16.3 9.6 8.2 12.2 18.4 10.4 12.2 11.2 5.7 15.9 5.1 12.7 6.2 18.5 12.7 7.7 6.3 10.7 7.9 11.7 19.2 21.7 10.4 4.2 20.0 7.5 15.3 9.4 15.4 8.3 19.9 14.1 14.2 4.1 11.0 11.4 10.5 2.1 12.1 6.9 12.6 11.1 13.4 5.5 8.1 2.3 5.7 59.6 3.9 21.7 14.0 5.4 10.0 9.9 13.7 11.9 13.4 10.4 13.9 12.7 14.7 11.5 12.3 13.1 2.5 14.1 10.7 6.3 14.3 12.0 7.1 9.8 14.8 7.1 7.4 5.0 12.6 3.4 9.8 13.9 PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291491-26372680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol Cytosol "CAB079289: AB_659890, HPA042122: , HPA042770: " "unprognostic (1.17e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-3)" "unprognostic (5.34e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (4.64e-3)" "unprognostic (3.65e-1)" "unprognostic (2.48e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-1)" "unprognostic (3.44e-2)" "unprognostic (1.16e-1)" 26.1 14.8 25.1 19.1 30.3 21.2 41.7 23.7 28.0 25.2 18.2 27.9 16.0 23.4 20.5 16.0 50.3 19.1 16.8 24.6 21.2 16.2 21.5 32.0 21.7 17.6 28.9 22.3 22.5 13.3 19.3 18.3 39.4 24.8 20.6 18.4 11.3 24.3 18.3 41.6 31.7 16.2 21.1 22.6 15.9 15.3 19.2 32.1 18.3 21.6 29.1 30.4 21.8 29.9 8.0 4.8 6.5 4.8 7.9 10.1 3.6 19.3 18.8 24.2 17.3 15.2 21.7 25.9 30.1 19.4 28.3 27.2 23.0 14.3 26.7 9.2 16.1 23.2 29.3 24.5 38.8 11.8 15.4 20.2 18.7 12.1 23.9 11.6 15.7 17.3 34.6 24.4 34.0 44.0 27.5 26.0 25.8 12.3 26.4 13.0 32.0 13.2 18.9 18.1 22.2 17.7 29.2 10.2 13.4 14.4 14.6 23.5 15.4 10.5 23.7 17.7 22.0 18.1 21.0 9.4 12.3 34.5 21.1 21.2 29.9 3.1 2.3 6.1 4.3 4.4 5.4 8.0 6.0 7.6 4.3 6.8 6.1 7.9 6.5 7.9 4.8 4.8 10.1 3.6 25.1 30.3 23.7 28.0 21.2 16.2 28.9 22.3 24.8 32.1 PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146581146-147084784 "Disease related genes, Predicted intracellular proteins" Apoptosis "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 73.2" "Cell line enriched" "Detected in some" 4 "HDLM-2: 46.4" "Cancer enriched" "Detected in some" 8 "glioma: 7.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 15.1;MAIT T-cell: 13.8;memory CD4 T-cell: 7.1;memory CD8 T-cell: 16.1;naive CD8 T-cell: 12.0;NK-cell: 9.5;T-reg: 8.0" "Group enriched" "Detected in many" 33 "NK-cells: 9.5;T-cells: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038118, HPA042122, HPA042770" Approved Approved Cytosol Cytosol "HPA038118: AB_10697238, HPA042122: , HPA042770: " "unprognostic (4.54e-5)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (2.80e-4)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-2)" "unprognostic (2.68e-1)" "unprognostic (3.20e-2)" "unprognostic (9.73e-4)" "unprognostic (4.51e-2)" "unprognostic (1.49e-8)" "unprognostic (2.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.48e-5)" "unprognostic (1.14e-4)" 2.0 9.7 30.8 2.5 35.2 2.9 1.8 10.2 73.2 1.6 2.7 26.0 0.0 3.0 1.7 1.8 2.9 14.5 2.9 2.9 26.4 20.9 4.7 2.4 2.5 4.3 25.5 22.4 1.6 2.9 16.0 6.4 2.6 27.5 2.7 2.8 4.6 2.0 2.9 1.5 4.9 2.3 3.5 18.6 2.9 2.2 15.7 29.3 0.0 4.2 0.0 2.4 6.8 1.1 0.0 0.0 0.3 0.0 9.5 16.1 4.1 0.4 0.4 2.4 1.0 0.1 0.1 0.2 0.5 0.2 1.1 1.5 1.3 4.7 0.2 0.1 0.0 10.0 0.8 1.0 1.1 46.4 0.2 0.6 2.7 0.5 0.1 0.0 0.2 0.1 0.6 0.0 0.2 0.1 0.6 0.5 0.7 0.3 0.0 0.0 6.1 1.0 0.7 0.1 0.1 4.1 10.7 1.9 0.2 0.3 0.0 0.2 0.4 0.1 0.3 0.2 0.7 2.5 0.4 0.3 0.2 0.0 1.7 4.2 1.3 0.2 0.0 0.0 15.1 0.0 13.8 0.0 7.1 16.1 0.0 0.0 1.3 12.0 0.3 9.5 0.0 0.0 8.0 4.1 30.8 35.2 10.2 34.1 26.4 20.9 25.5 22.4 27.5 29.3 PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4" "Cell line enhanced" "Detected in some" "A-431: 15.4;A549: 22.7;CAPAN-2: 15.2;MCF7: 18.7;PC-3: 21.5;SCLC-21H: 20.8;U-2 OS: 12.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Enhanced Cytosol Cytosol "HPA042122: , HPA042770: , HPA060473: " "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavourable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" 1.5 6.6 28.2 1.6 33.9 1.1 2.4 17.0 78.4 11.8 1.5 13.8 0.5 1.7 25.3 7.0 25.2 10.5 1.4 1.9 25.8 19.5 1.2 1.1 1.1 1.3 25.6 19.3 1.3 1.7 1.1 5.9 1.1 19.1 5.5 1.4 0.4 1.4 14.4 1.7 28.8 2.0 11.8 32.0 1.3 1.9 4.7 13.5 0.0 1.1 3.9 3.6 1.5 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.4 22.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 9.9 0.0 7.1 11.1 0.3 0.0 0.0 1.3 0.0 1.5 1.7 0.3 0.0 0.0 3.3 5.9 0.0 0.0 0.0 0.0 0.0 3.0 18.7 0.0 0.0 1.1 21.5 0.0 0.0 0.6 0.0 0.0 20.8 4.0 0.7 0.0 0.0 9.6 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 33.9 17.0 40.2 25.8 19.5 25.6 19.3 19.1 13.5 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965673-136147891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.6" "Cell line enhanced" "Detected in many" "A-431: 18.9;BJ hTERT+: 18.5;RPTEC TERT1: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: " "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavourable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavourable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favourable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (3.91e-4)" 6.3 3.3 3.4 1.9 6.4 0.7 4.3 1.5 4.9 5.5 6.7 5.2 5.8 1.7 6.8 5.1 5.0 3.0 3.3 27.4 3.9 2.8 31.7 1.2 2.6 0.9 7.0 4.4 3.7 3.8 7.5 3.7 9.0 5.3 3.8 3.5 1.6 7.7 7.8 85.6 10.4 2.5 11.4 6.1 1.2 5.2 4.2 6.5 0.0 2.3 31.6 1.2 6.5 3.9 1.5 1.8 1.7 1.4 1.8 1.5 0.6 18.9 1.0 5.4 2.6 4.4 5.6 6.3 14.8 18.5 7.0 8.7 1.2 1.2 0.0 5.7 15.1 2.4 2.2 5.2 15.2 0.0 0.7 0.8 0.5 0.0 3.1 0.0 0.7 5.0 4.5 8.9 4.2 6.7 0.5 0.0 10.1 3.1 0.1 0.1 3.7 3.6 0.0 8.0 0.0 24.6 0.7 0.4 3.0 2.4 3.0 5.7 4.7 0.2 4.3 7.3 4.0 9.9 6.5 0.2 0.5 0.0 5.4 0.4 2.5 1.1 1.2 1.5 0.9 1.4 0.5 0.7 1.0 0.8 1.1 1.5 1.5 1.2 1.7 1.8 1.2 1.8 0.7 0.6 3.4 6.4 1.5 4.9 3.9 2.8 7.0 4.4 5.3 6.5 PPP2R3B "PPP2R3L, PPP2R3LY, PR48, PR70" ENSG00000167393 "Protein phosphatase 2 regulatory subunit B''beta" Q9Y5P8 X 333963-386955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 43.5" "Cell line enhanced" "Detected in many" "PC-3: 15.2;U-698: 23.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026606 Supported Nucleoplasm Nucleoplasm "HPA026606: " "unprognostic (1.25e-1)" "unprognostic (4.35e-3)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (6.03e-2)" "unprognostic (2.46e-3)" "unprognostic (1.56e-2)" "unprognostic (2.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-2)" "prognostic favourable (2.92e-5)" "unprognostic (4.65e-2)" "unprognostic (2.29e-8)" "unprognostic (1.15e-1)" "unprognostic (4.97e-2)" "unprognostic (3.17e-1)" "prognostic favourable (1.90e-5)" 1.8 1.3 8.8 1.1 11.7 3.8 4.8 9.1 8.7 7.6 1.2 0.0 0.0 1.4 6.6 0.7 2.4 2.3 1.4 17.7 12.2 2.9 4.1 1.1 1.5 1.7 15.4 6.2 6.9 2.9 1.5 11.0 8.9 13.0 2.4 0.7 0.0 1.6 1.2 43.5 3.9 1.3 1.6 8.3 1.8 1.8 4.1 15.0 0.0 1.0 0.0 0.9 2.9 2.6 0.1 0.6 2.3 0.1 0.0 1.3 0.1 0.5 5.2 0.7 2.2 0.1 0.2 7.0 5.8 1.5 5.2 6.2 5.2 0.0 0.0 3.2 4.4 0.0 0.2 0.0 1.3 3.7 4.2 1.2 1.8 0.2 0.0 1.9 2.2 0.1 0.1 0.0 3.2 0.1 1.0 0.3 1.2 2.6 8.8 7.7 2.3 15.2 4.0 3.4 0.3 1.4 1.5 0.0 9.0 0.0 0.9 4.1 0.0 2.3 0.3 3.1 2.9 0.0 1.9 0.0 0.0 23.8 0.1 2.6 3.9 0.0 0.0 2.3 0.1 0.1 1.3 0.1 0.1 0.0 0.6 0.1 0.3 0.3 0.1 0.0 0.1 0.5 0.0 0.1 8.8 11.7 9.1 8.7 12.2 2.9 15.4 6.2 13.0 15.0 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell line specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavourable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.4 21.6 16.4 7.4 21.4 19.7 8.7 9.2 7.9 24.3 9.2 9.0 19.3 9.7 13.9 28.5 14.8 22.6 6.4 14.7 19.7 10.2 15.8 23.5 7.5 16.9 15.0 18.9 21.7 16.3 5.7 25.5 13.9 23.3 4.9 17.7 6.4 8.9 9.0 34.9 10.7 8.4 15.4 30.3 11.5 17.7 15.2 10.2 13.6 13.4 18.9 20.6 23.4 18.8 14.1 11.9 12.2 16.4 11.4 13.3 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria Mitochondria "HPA008233: AB_1855661, HPA008823: " "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavourable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favourable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.9 17.0 5.7 25.4 10.3 15.3 13.5 24.4 23.8 12.6 7.3 9.6 12.7 16.4 16.0 15.1 26.8 16.3 16.3 22.0 11.9 9.0 20.1 34.8 6.0 14.3 14.9 7.7 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.9 12.9 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.6 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favourable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 18.0 8.3 6.9 13.7 8.1 15.2 21.1 11.9 12.0 10.3 10.2 10.9 3.7 6.1 13.4 7.8 11.6 9.0 10.7 27.5 7.6 7.3 8.9 8.2 16.5 22.3 7.7 4.9 10.1 9.9 13.7 15.1 12.7 9.9 11.1 7.1 20.7 15.5 6.0 52.4 9.1 9.8 13.5 7.9 14.1 9.5 41.6 6.9 6.8 11.5 13.2 20.0 14.7 11.0 15.5 4.0 6.6 2.9 11.9 16.0 3.9 5.4 4.0 3.6 4.4 9.6 11.9 5.3 7.6 13.5 11.4 12.6 2.3 3.4 20.8 9.4 11.8 3.9 8.3 7.6 14.6 11.9 4.4 4.4 4.6 6.7 13.0 3.2 7.4 7.2 10.6 7.6 7.9 9.8 8.7 27.8 12.7 2.5 7.5 5.2 2.6 5.6 24.5 8.5 6.9 10.6 5.2 2.5 6.0 5.7 3.4 7.8 2.3 5.4 10.5 17.7 3.8 26.8 5.9 13.9 16.7 21.8 9.4 4.2 11.7 3.4 1.6 6.6 11.4 2.0 8.7 15.5 12.9 16.0 3.2 13.9 12.4 10.1 0.4 11.9 2.9 4.0 10.1 3.9 6.9 8.1 11.9 12.0 7.6 7.3 7.7 4.9 9.9 6.9 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Approved "Plasma membrane,Cytosol" 43000 "Plasma membrane, Cytosol" "CAB005610: AB_325975, HPA047157: " "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavourable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavourable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 25.8 20.1 43.3 15.9 66.2 32.3 25.7 47.9 78.2 14.8 14.0 7.7 6.9 13.1 16.6 14.2 15.7 10.5 14.7 10.2 56.2 28.7 11.3 29.6 15.5 18.8 23.7 45.1 13.6 9.8 9.4 8.9 18.5 25.4 14.3 14.8 6.8 12.1 16.6 41.7 17.1 12.0 18.5 21.6 16.5 12.6 10.4 16.5 12.7 12.6 7.7 20.1 14.4 13.3 1.0 1.8 6.4 1.4 0.9 1.4 0.9 17.4 14.9 20.2 13.9 14.0 16.2 20.6 25.5 21.7 28.7 25.4 21.5 15.9 24.4 8.8 17.2 11.9 21.3 18.4 35.1 17.2 15.2 79.3 12.2 19.8 27.6 31.1 26.8 16.3 16.7 22.3 22.9 19.2 19.1 27.9 20.9 15.1 26.3 27.4 23.7 12.7 19.2 26.7 38.9 17.8 18.7 26.7 18.8 14.6 20.8 18.3 9.8 14.5 20.2 24.8 22.8 18.7 21.9 15.8 17.4 36.2 18.1 32.7 15.5 3.2 1.2 2.9 0.7 0.8 1.4 0.5 0.8 0.5 1.3 1.0 0.9 1.4 6.4 0.9 1.4 1.8 0.9 0.9 43.3 66.2 47.9 78.2 56.2 28.7 23.7 45.1 25.4 16.5 PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591615-101595021 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "testis: 81.9" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047157 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA047157: " "unprognostic (8.81e-2)" "unprognostic (2.65e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085377 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: " "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 24.7 26.6 13.5 26.1 14.1 26.7 18.6 16.0 15.9 19.2 28.4 14.5 20.5 22.5 19.2 28.4 39.1 17.7 31.9 28.5 12.6 12.1 28.9 52.3 27.4 25.3 12.5 12.8 22.5 26.3 23.9 16.2 51.6 11.9 18.3 17.4 18.8 22.0 14.9 26.0 26.1 38.8 15.9 11.9 36.2 22.6 39.0 9.5 59.7 27.1 26.5 37.9 22.2 21.1 19.5 30.3 57.3 28.2 12.4 23.6 12.0 30.3 34.1 22.8 31.8 21.6 18.2 35.4 27.1 30.2 35.7 39.7 30.0 39.7 23.7 34.9 31.9 24.8 28.2 33.6 21.1 29.6 50.5 16.1 21.2 66.2 32.8 22.6 30.5 26.4 29.8 32.5 20.6 41.4 31.3 21.7 27.2 87.6 39.3 41.2 43.3 18.2 44.0 23.7 41.2 33.7 31.3 22.2 32.8 13.3 40.2 23.1 37.0 38.5 26.3 20.9 21.9 16.8 20.8 37.2 40.9 27.7 29.8 29.1 25.2 21.4 26.9 57.3 18.3 28.2 13.1 17.0 19.2 20.6 30.3 19.5 17.2 15.2 56.9 12.4 24.5 23.5 23.6 12.0 13.5 14.1 16.0 15.9 12.6 12.1 12.5 12.8 11.9 9.5 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46346994-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol 47000 "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: " "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavourable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 18.9 24.7 23.0 18.1 28.8 13.4 15.9 25.2 50.8 20.4 21.1 19.4 15.2 18.0 23.0 15.2 20.1 27.8 20.5 48.2 20.8 23.9 22.6 22.1 17.4 19.3 21.9 29.8 16.7 21.5 26.3 23.9 17.3 34.5 19.5 17.5 19.7 21.0 21.4 40.8 16.4 15.3 23.5 16.2 21.7 20.6 19.0 15.3 15.6 18.1 20.5 16.1 17.1 18.1 10.6 11.1 1.9 14.1 14.0 19.8 8.9 19.5 36.8 22.0 16.6 16.6 17.8 10.2 24.3 19.8 29.6 26.7 26.4 15.6 30.0 13.3 17.7 16.1 28.9 28.7 8.9 20.8 39.2 25.0 27.0 18.7 18.5 33.8 17.5 16.2 13.6 20.8 15.5 25.4 24.0 15.5 16.8 21.2 18.9 63.4 16.6 20.1 28.2 19.0 24.0 17.7 26.8 31.3 23.0 20.4 26.0 8.7 16.3 21.6 21.1 13.0 21.6 9.6 25.4 12.5 28.7 36.0 13.9 28.4 21.6 0.0 6.8 1.9 19.8 12.1 12.7 10.6 9.2 15.3 11.1 8.7 8.9 12.0 0.1 14.0 14.1 7.9 9.3 8.9 23.0 28.8 25.2 50.8 20.8 23.9 21.9 29.8 34.5 15.3 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain "HPA050940: " "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favourable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 21.7 20.1 20.1 15.7 24.5 24.8 21.2 20.8 26.2 17.0 19.1 25.9 15.1 13.9 15.6 17.2 21.2 14.0 12.9 15.3 19.8 16.6 22.8 17.8 16.3 21.5 20.1 16.1 17.5 27.7 21.3 17.3 17.6 17.8 14.5 21.8 16.8 26.9 14.6 50.5 19.3 17.3 16.3 22.6 19.4 16.5 22.8 23.7 34.1 22.2 20.5 24.0 13.8 15.6 17.3 14.8 32.2 19.5 13.9 23.3 13.8 14.3 10.5 19.2 18.1 20.6 17.3 19.4 15.3 16.6 22.6 18.9 16.8 15.3 20.7 11.9 20.5 29.4 25.9 16.6 26.3 18.5 12.5 17.0 16.5 14.9 16.9 29.6 23.6 14.2 22.8 18.5 17.8 21.0 19.9 24.1 24.3 21.4 27.9 18.7 17.8 19.6 22.8 29.0 27.7 19.2 14.5 19.9 19.7 27.3 22.0 17.7 34.0 18.7 20.4 13.9 13.3 27.0 20.2 26.6 48.0 27.5 18.7 19.4 22.6 27.2 13.2 21.4 14.7 17.4 18.0 17.3 18.9 16.6 14.8 13.3 18.9 17.5 32.2 13.9 19.5 10.7 23.3 13.8 20.1 24.5 20.8 26.2 19.8 16.6 20.1 16.1 17.8 23.7 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40071461-40097727 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 86.0;THP-1: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 130000 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 33.3 27.1 37.6 31.0 41.5 33.3 39.7 35.2 41.0 30.3 21.0 31.5 17.2 12.9 31.3 19.4 18.5 20.7 23.2 18.1 32.7 35.8 29.4 18.4 47.3 48.5 35.3 29.1 24.7 17.4 30.4 21.2 25.9 34.6 28.0 26.0 26.3 22.1 23.6 8.3 13.8 16.6 36.5 33.6 61.3 17.9 13.8 29.1 19.8 18.7 14.4 30.0 23.0 19.8 9.3 77.4 59.9 90.0 7.2 19.1 91.6 10.0 6.8 11.0 6.2 13.3 11.4 21.6 5.6 10.2 13.6 16.8 39.2 16.9 11.5 11.0 5.9 17.7 17.1 10.1 18.7 14.5 17.6 6.0 16.8 19.3 15.1 13.5 14.5 10.7 11.1 10.8 10.1 18.3 13.9 16.8 7.6 20.1 7.7 10.1 20.8 10.6 8.7 14.8 20.0 9.5 18.0 8.8 9.3 11.0 86.0 34.2 12.5 159.9 6.4 6.6 14.2 6.2 16.7 15.1 31.6 11.1 8.5 33.0 12.0 6.2 90.0 48.2 9.9 77.6 11.8 9.3 14.7 11.5 77.4 9.2 19.1 14.7 59.9 7.2 58.3 7.6 16.8 91.6 37.6 41.5 35.2 41.0 32.7 35.8 35.3 29.1 34.6 29.1 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163680 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 16.0;EFO-21: 11.8;HEK 293: 20.4;MCF7: 8.7;RPTEC TERT1: 10.1;SK-MEL-30: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavourable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 8.5 13.1 10.4 9.3 10.6 3.0 9.6 21.9 11.8 16.1 10.5 13.1 11.7 15.8 13.8 14.9 13.7 14.2 10.6 12.3 10.7 7.5 17.8 13.1 14.3 6.6 12.2 7.7 25.1 7.0 3.1 7.7 14.3 9.8 10.5 9.6 16.1 7.2 11.4 19.1 30.9 6.9 10.4 7.1 11.8 15.2 6.4 11.5 11.5 7.4 13.2 8.1 13.9 12.0 0.2 0.0 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 16.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.8 4.8 1.6 2.6 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.1 0.0 1.2 0.0 0.0 0.4 1.0 8.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.1 7.0 0.2 13.3 0.0 0.4 0.0 0.0 6.0 0.0 0.0 0.5 7.1 0.9 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.4 0.0 10.4 10.6 21.9 11.8 10.7 7.5 12.2 7.7 9.8 11.5 PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" "Nuclear bodies" "HPA019353: AB_1855668, HPA019360: AB_1855669" "unprognostic (3.31e-2)" "unprognostic (2.07e-2)" "unprognostic (6.78e-2)" "unprognostic (2.85e-1)" "unprognostic (9.61e-2)" "unprognostic (1.22e-2)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.37e-1)" "unprognostic (4.97e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-3)" "unprognostic (5.72e-2)" "prognostic unfavourable (6.72e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" 17.5 15.8 24.3 23.5 26.1 26.0 18.9 28.3 29.7 21.3 16.5 17.9 16.8 15.0 22.0 20.9 17.3 20.4 17.1 14.9 20.0 12.6 14.2 17.3 16.3 28.7 20.9 18.3 26.0 18.6 22.7 26.9 20.9 20.9 18.7 21.5 13.1 16.6 17.7 18.0 23.7 21.2 16.9 19.3 28.9 17.8 19.1 21.1 32.4 19.5 15.2 26.7 16.7 23.7 15.6 13.5 18.1 12.3 15.4 23.3 14.5 19.7 13.1 19.6 18.9 17.3 21.4 20.9 19.2 13.7 20.7 26.0 19.7 19.6 22.4 15.3 13.8 17.6 21.2 19.7 28.1 18.7 18.5 13.9 20.5 17.2 15.0 12.9 14.6 17.0 8.1 19.9 14.2 17.8 18.9 15.8 16.4 19.9 19.8 16.3 13.8 7.7 18.5 26.2 18.9 12.1 16.7 10.0 7.9 18.9 8.2 17.1 12.0 17.0 13.5 11.4 16.0 12.3 28.1 9.0 13.4 23.5 12.5 19.0 12.1 18.1 10.1 16.7 17.2 11.1 20.7 15.6 18.9 18.7 13.5 12.3 23.3 20.4 8.2 15.4 12.3 7.8 20.7 14.5 24.3 26.1 28.3 29.7 20.0 12.6 20.9 18.3 20.9 21.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol 1400000 Cytosol "CAB025414: , HPA031388: , HPA031389: , HPA031390: " "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavourable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 10.8 13.3 14.2 15.9 33.6 19.9 14.0 14.6 13.7 19.3 20.5 16.9 6.9 13.9 14.4 17.1 16.9 20.9 42.8 22.0 21.0 20.4 18.7 11.2 19.2 13.0 18.8 13.7 18.5 26.1 13.9 35.8 18.0 31.8 24.9 23.3 17.6 12.5 19.1 13.7 13.3 19.4 24.5 9.1 14.4 25.9 18.6 26.5 12.8 21.5 10.2 9.2 30.2 18.1 8.9 12.3 11.1 17.9 7.3 4.8 18.2 15.7 20.5 27.6 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB005050: AB_562037, HPA035409: , HPA064946: " "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.3 11.8 9.5 12.6 23.5 24.5 9.0 19.3 19.8 14.5 13.0 11.1 14.7 6.7 9.0 19.8 9.2 8.7 17.6 27.5 19.6 7.9 13.3 27.3 8.8 19.4 12.6 14.0 22.6 8.6 19.4 20.0 21.4 6.2 19.4 21.6 5.4 11.6 9.9 4.1 14.3 9.8 20.3 9.8 22.3 19.3 8.2 8.3 33.9 22.6 11.5 11.9 10.5 22.9 26.2 14.2 15.1 15.7 7.7 6.0 8.0 16.4 27.4 13.9 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;RPTEC TERT1: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" "Nuclear speckles" "Golgi apparatus" "HPA044540: " "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavourable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavourable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favourable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.5 4.3 3.8 4.7 0.0 0.6 0.6 0.0 7.8 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 0.8 0.0 0.0 1.0 0.1 0.0 0.0 5.5 5.4 0.0 0.0 0.0 14.0 1.2 2.0 5.4 5.7 0.1 0.0 3.2 0.0 0.0 1.5 2.3 2.7 6.3 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 PRKAB2 ENSG00000131791 "Protein kinase AMP-activated non-catalytic subunit beta 2" O43741 1 147155106-147172550 "Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 52.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044342 Approved Approved Nucleoplasm Nucleoplasm "HPA044342: AB_10966508" "prognostic unfavourable (4.55e-4)" "unprognostic (2.03e-2)" "unprognostic (1.84e-1)" "unprognostic (4.03e-2)" "unprognostic (9.59e-3)" "prognostic unfavourable (7.32e-4)" "unprognostic (6.30e-2)" "unprognostic (1.23e-1)" "unprognostic (3.06e-2)" "unprognostic (6.78e-2)" "unprognostic (4.65e-2)" "unprognostic (1.98e-1)" "unprognostic (5.34e-2)" "unprognostic (1.31e-1)" "unprognostic (3.57e-1)" "prognostic unfavourable (6.78e-7)" "unprognostic (4.78e-2)" 7.7 7.6 5.6 4.6 7.1 4.7 7.6 13.3 10.9 9.3 24.6 8.9 8.9 19.1 13.0 8.1 10.0 7.4 6.5 15.2 5.6 5.2 6.2 32.6 6.3 3.8 5.9 9.3 8.1 21.0 18.4 6.2 7.5 7.8 10.9 6.9 6.3 5.7 12.6 52.1 9.4 19.1 20.5 8.4 5.7 11.1 6.9 5.5 2.6 5.8 19.9 4.7 19.0 10.3 1.2 1.7 2.9 1.6 5.1 2.5 0.8 4.0 2.2 5.9 4.6 14.1 12.2 21.6 7.6 4.2 5.1 5.6 8.9 8.0 7.2 3.9 6.0 10.7 6.9 8.4 5.0 2.8 4.8 3.2 7.1 14.3 9.7 3.7 1.4 9.6 17.1 5.3 25.0 5.0 4.5 3.0 4.3 4.0 2.8 2.1 12.5 9.9 4.4 8.0 3.5 3.7 3.2 3.8 7.2 5.7 6.5 27.0 6.1 4.7 5.6 5.8 12.8 5.3 12.2 4.8 5.1 3.7 6.0 3.3 7.5 2.9 1.2 1.9 1.5 1.2 2.5 1.2 1.6 0.9 1.7 1.1 1.7 1.1 0.3 5.1 1.6 0.8 0.7 0.8 5.6 7.1 13.3 10.9 5.6 5.2 5.9 9.3 7.8 5.5 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved Cytosol 1300000 Cytosol "CAB010361: AB_2268772, HPA071185: " "unprognostic (1.08e-1)" "prognostic favourable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavourable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favourable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 25.6 43.4 19.6 17.8 22.7 9.1 34.1 29.1 39.6 20.6 17.5 16.0 16.2 13.4 19.8 15.6 20.9 18.8 16.4 91.6 20.7 29.4 14.7 34.5 16.5 28.2 21.6 27.5 47.0 15.6 20.8 24.6 15.4 26.9 16.6 16.2 18.4 15.5 24.9 92.4 13.4 14.4 29.0 16.2 28.1 13.9 24.4 11.1 15.2 15.7 26.2 14.8 21.1 17.3 1.7 2.4 8.6 5.3 0.7 1.7 1.2 25.7 15.0 34.0 40.5 30.1 32.0 6.1 27.4 25.4 39.0 35.8 18.2 9.2 11.1 22.2 43.4 16.9 23.9 26.0 37.1 20.3 12.0 20.5 28.3 17.6 25.8 12.6 21.7 30.4 12.5 31.0 10.8 32.8 19.2 29.2 39.8 38.2 28.4 9.5 12.2 33.4 25.7 31.4 25.7 19.0 16.3 26.8 17.1 24.8 15.2 11.3 21.7 12.2 25.4 46.1 12.9 61.6 25.6 20.2 20.7 16.4 30.9 19.2 17.2 0.3 3.4 0.4 1.7 5.3 0.8 1.7 0.9 1.1 2.4 1.3 1.2 1.7 8.6 0.7 4.6 1.6 0.8 1.2 19.6 22.7 29.1 39.6 20.7 29.4 21.6 27.5 26.9 11.1 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved Cytosol 1500000 Cytosol "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: " "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavourable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favourable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 7.0 21.5 40.0 10.5 57.0 6.2 8.0 54.7 85.5 9.4 23.6 16.9 3.9 4.8 8.7 17.6 8.1 5.2 11.5 10.1 43.1 52.1 10.6 9.0 6.9 16.2 38.3 33.5 8.3 11.9 12.2 18.3 5.1 35.5 13.8 22.6 4.9 32.9 12.7 3.2 2.6 6.3 12.6 47.7 14.6 14.2 3.6 25.9 25.5 11.1 1.8 15.3 13.5 4.6 13.5 7.1 17.1 5.4 25.9 27.6 22.0 3.1 6.2 9.9 11.9 11.5 10.1 4.6 15.4 11.7 7.8 7.4 0.1 2.8 16.3 10.6 12.0 2.1 4.6 5.0 8.4 15.9 2.5 35.9 8.5 1.2 11.3 14.2 0.8 6.0 2.2 7.6 4.3 36.1 1.1 9.4 12.8 0.5 18.4 7.5 9.8 4.4 14.3 15.5 9.9 19.1 11.1 3.2 12.7 8.5 3.3 9.4 3.0 3.0 32.0 10.9 8.5 11.1 11.6 7.0 8.4 16.5 5.2 15.1 13.6 17.1 2.7 5.8 23.3 3.6 18.7 13.5 17.3 20.6 7.1 10.2 26.4 27.6 1.5 25.9 5.4 4.1 15.9 22.0 40.0 57.0 54.7 58.2 43.1 52.1 38.3 33.5 35.5 25.9 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012529-69014113 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 27.4" "Cell line enhanced" "Detected in single" "CACO-2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Approved Cytosol Cytosol "CAB004530: AB_628137, HPA071185: " "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556111-151877125 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 77.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.46e-2)" "unprognostic (9.29e-2)" "unprognostic (1.76e-1)" "unprognostic (4.33e-3)" "unprognostic (7.13e-2)" "unprognostic (8.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.80e-1)" "unprognostic (3.61e-2)" "unprognostic (4.52e-1)" 12.8 5.5 15.3 8.7 28.8 6.3 9.7 31.1 19.2 8.8 11.5 7.5 9.4 16.7 10.4 10.9 10.8 8.6 12.0 77.2 15.1 13.5 15.4 18.5 8.6 7.7 12.3 14.3 6.8 6.2 6.7 5.1 20.0 18.3 17.5 13.5 7.8 11.9 14.8 21.5 6.9 17.8 32.8 8.5 12.8 13.8 9.7 9.5 2.3 12.6 5.2 7.1 22.4 12.4 7.9 7.8 18.4 6.0 3.1 6.1 3.5 18.2 5.3 3.6 4.2 16.4 14.0 6.4 8.4 7.6 9.1 8.9 3.4 23.4 0.0 13.9 11.2 5.9 2.2 9.8 14.8 4.4 2.5 4.9 0.6 0.4 24.4 3.6 4.7 6.8 21.0 9.1 9.7 15.6 1.6 2.3 27.5 6.9 1.9 2.6 3.7 15.5 1.8 2.6 3.8 17.3 4.4 16.1 2.5 4.9 9.2 3.7 2.9 4.9 20.8 2.1 1.8 1.0 5.3 1.6 1.9 0.0 25.9 11.3 20.4 18.4 6.0 10.5 5.1 5.4 3.7 7.9 4.5 4.5 4.3 3.8 4.2 6.1 13.6 3.1 5.4 7.8 2.4 3.5 15.3 28.8 31.1 19.2 15.1 13.5 12.3 14.3 18.3 9.5 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol 11000000 Cytosol "CAB019378: , HPA049979: " "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 47.1 48.0 41.7 34.5 54.8 14.6 38.7 40.4 57.4 48.2 23.8 44.9 31.4 15.1 43.6 37.7 29.6 43.2 37.4 122.7 42.5 52.3 49.2 43.4 47.3 29.5 50.1 43.6 62.5 19.1 107.8 41.9 47.3 57.7 35.6 24.2 32.2 47.5 43.6 99.8 22.8 19.3 39.4 52.8 35.3 25.1 36.9 40.1 28.2 51.8 23.6 29.2 33.8 33.4 11.3 26.9 52.6 28.7 18.5 13.0 22.9 16.4 31.6 40.6 24.3 54.2 61.6 6.1 22.2 45.8 34.7 30.7 12.3 22.2 16.7 15.3 48.4 13.6 30.0 36.0 49.9 11.3 10.7 25.8 27.5 40.2 39.3 19.7 29.0 44.0 37.4 40.0 33.8 57.6 11.6 26.3 42.0 31.1 21.7 10.6 15.0 21.6 15.2 67.3 18.4 52.6 35.8 14.8 20.0 20.3 37.2 85.5 29.0 27.9 40.8 49.0 23.4 22.1 20.6 21.9 15.5 24.9 29.6 18.8 30.5 31.1 26.1 46.3 13.0 25.5 13.0 11.3 9.8 11.6 26.9 8.5 8.9 9.8 52.6 18.5 28.7 8.8 12.3 22.9 41.7 54.8 40.4 57.4 42.5 52.3 50.1 43.6 57.7 40.1 PRKAR1B ENSG00000188191 "Protein kinase cAMP-dependent type I regulatory subunit beta" P31321 7 549197-727650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 83.6" "Cell line enhanced" "Detected in many" "NTERA-2: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026719 Approved "HPA026719: AB_1855419" "unprognostic (4.90e-2)" "unprognostic (4.92e-2)" "unprognostic (2.69e-1)" "unprognostic (4.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.02e-3)" "unprognostic (3.28e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-1)" "unprognostic (1.41e-2)" "unprognostic (2.01e-3)" "unprognostic (1.95e-1)" "unprognostic (3.38e-3)" "unprognostic (5.18e-2)" "unprognostic (2.64e-1)" "unprognostic (9.23e-2)" "unprognostic (2.00e-1)" 5.0 6.8 33.6 4.3 30.4 4.5 4.0 24.0 83.6 4.8 5.7 3.4 1.6 7.2 7.2 2.7 4.2 6.2 4.6 7.7 35.5 42.8 5.4 3.8 5.5 5.2 22.5 29.2 12.9 4.1 5.6 7.0 3.5 29.7 6.0 4.2 2.5 3.9 5.5 3.8 3.0 7.6 5.3 9.1 8.2 3.8 4.8 3.7 2.5 2.9 1.4 3.3 3.5 2.6 7.0 5.5 1.5 2.6 3.5 12.8 10.3 24.8 17.2 2.6 6.3 1.7 1.5 7.3 5.0 2.3 3.2 1.8 30.7 5.5 18.9 3.5 2.2 18.4 8.6 9.5 1.3 3.9 6.2 1.2 11.1 20.2 3.2 11.9 3.0 4.2 3.0 2.1 6.1 3.4 18.0 3.8 2.8 23.9 14.4 7.8 40.3 6.8 9.3 0.5 8.4 8.0 6.5 33.7 25.5 12.7 12.6 9.9 6.5 4.5 4.1 1.4 3.2 1.9 10.1 2.4 6.8 12.3 2.6 9.3 18.8 1.5 2.0 0.0 4.6 2.6 6.9 6.2 7.9 7.1 2.4 7.0 12.8 11.7 0.8 3.5 0.9 5.5 5.2 10.3 33.6 30.4 24.0 68.6 35.5 42.8 22.5 29.2 29.7 3.7 PRKAR2A PRKAR2 ENSG00000114302 "Protein kinase cAMP-dependent type II regulatory subunit alpha" P13861 3 48744597-48847846 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005023, HPA038268" Uncertain 350000 "CAB005023: AB_562330, HPA038268: " "unprognostic (2.81e-2)" "unprognostic (3.59e-1)" "prognostic favourable (4.27e-5)" "unprognostic (1.60e-1)" "unprognostic (4.01e-2)" "unprognostic (6.17e-3)" "prognostic unfavourable (1.97e-4)" "unprognostic (4.77e-2)" "unprognostic (2.65e-1)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (9.18e-2)" "prognostic favourable (2.07e-4)" "unprognostic (3.59e-2)" "unprognostic (3.54e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-2)" 14.4 14.0 7.7 8.2 7.9 10.0 8.7 8.3 9.1 11.0 13.9 9.7 12.7 7.9 10.5 9.6 13.7 11.2 10.6 16.8 6.5 8.4 13.2 20.1 8.1 7.2 7.7 7.9 13.2 9.2 11.6 6.9 7.0 7.9 10.6 12.4 11.3 14.3 13.5 47.7 9.5 12.6 10.6 6.9 8.3 9.7 58.4 6.1 3.2 11.0 14.2 10.6 13.3 13.9 8.1 8.7 13.3 14.6 9.7 10.1 6.7 17.1 11.6 9.7 7.5 14.6 14.9 10.9 19.8 9.9 17.4 11.0 15.3 7.7 15.1 13.9 20.5 7.9 27.7 17.3 23.5 12.4 10.2 20.2 21.1 11.2 10.8 21.1 13.0 12.4 13.6 22.3 16.5 18.3 22.6 9.7 16.3 6.7 0.1 6.9 6.9 12.9 6.4 12.3 19.2 11.2 18.9 9.6 9.9 19.4 23.3 13.1 15.6 16.5 23.1 15.3 12.3 24.9 27.1 16.7 31.9 14.7 20.6 23.4 11.6 10.9 9.1 10.5 10.1 8.1 9.7 8.1 8.5 8.6 8.7 7.6 6.1 6.0 13.3 9.7 14.6 5.4 7.4 6.7 7.7 7.9 8.3 9.1 6.5 8.4 7.7 7.9 7.9 6.1 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044649-107161811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "adipose tissue: 80.2;breast: 114.1" "Cell line enhanced" "Detected in many" "AN3-CA: 19.7;Daudi: 27.0;K-562: 16.3;U-698: 69.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "myeloid DC: 3.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria 1600000 Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favourable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favourable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavourable (8.74e-4)" "unprognostic (7.15e-2)" 80.2 21.5 9.4 6.0 17.2 8.4 114.1 4.5 17.0 3.9 9.1 1.9 2.4 3.1 5.1 3.9 8.4 3.4 4.7 9.0 8.8 8.6 4.5 2.4 3.2 3.0 8.4 12.1 19.5 6.5 5.6 8.1 10.7 3.0 6.4 5.5 2.6 6.8 3.9 2.2 1.6 4.7 7.4 3.4 11.1 4.1 14.5 4.6 0.8 1.6 2.8 3.3 8.4 11.8 0.2 3.1 1.3 1.5 0.5 0.1 2.5 0.0 0.4 2.5 19.7 10.6 0.0 0.0 1.0 3.2 0.8 0.7 0.0 0.0 27.0 0.2 0.6 0.0 1.9 0.0 1.5 0.7 2.2 9.0 0.0 0.0 2.9 0.1 1.2 0.1 0.0 0.0 0.0 11.9 16.3 0.8 0.0 2.0 3.7 0.1 4.8 0.7 1.0 0.0 0.0 0.0 0.0 3.2 4.7 1.4 0.3 1.0 0.6 1.9 6.7 0.9 2.6 0.0 1.9 0.6 0.0 69.4 0.7 4.7 9.4 1.3 1.5 0.0 0.0 1.4 0.1 0.2 0.0 0.0 3.1 0.0 0.1 0.1 0.7 0.5 0.7 1.1 0.0 2.5 9.4 17.2 4.5 17.0 8.8 8.6 8.4 12.1 3.0 4.6 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.3 2.5 2.6 6.2 15.9 0.3 13.3 8.7 9.6 8.2 1.4 1.5 3.1 3.6 21.4 0.3 1.3 1.5 20.9 5.1 3.0 0.0 7.3 6.4 8.5 3.8 20.9 6.9 0.6 12.0 10.3 8.2 8.0 0.0 14.8 0.7 7.7 2.3 1.0 6.6 1.4 18.8 0.0 3.4 2.0 1.5 8.5 4.4 2.5 0.1 0.3 5.4 24.5 16.7 9.7 10.4 8.3 0.0 0.0 0.3 53.0 0.0 8.2 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell line enhanced" "Detected in some" "HEL: 40.8;HMC-1: 40.9;K-562: 58.1;THP-1: 18.4;U-937: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: , HPA054203: " "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 40.8 1.9 0.0 0.0 5.9 40.9 0.0 0.1 0.0 0.0 0.0 58.1 0.1 0.0 0.0 12.9 12.9 0.3 0.0 12.3 0.1 2.3 0.1 3.6 7.1 0.0 0.0 0.0 0.6 0.0 18.4 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 16.4 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 63.3;THP-1: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavourable (2.24e-4)" "prognostic favourable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.7 3.0 1.2 2.0 9.0 5.2 11.2 4.7 5.9 5.8 5.7 7.3 7.6 20.0 2.1 10.2 3.5 7.9 11.5 4.7 17.4 6.0 11.1 4.1 7.8 5.7 14.6 25.1 4.1 8.4 5.9 5.5 5.0 2.2 2.9 8.3 19.1 1.6 24.9 3.1 5.5 1.7 3.0 4.7 6.3 16.7 2.0 1.4 3.6 63.3 9.7 5.3 45.2 7.2 2.8 3.6 3.7 4.4 4.4 6.8 10.2 6.7 25.2 5.4 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Cell line enhanced" "Detected in many" "REH: 19.1;TIME: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA044496, HPA054252" Enhanced Supported Approved Vesicles Vesicles "CAB001948: , HPA044496: , HPA054252: " "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favourable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favourable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.3 2.0 2.8 2.8 4.3 5.1 2.3 3.8 6.8 3.2 3.4 0.5 5.3 8.1 3.6 3.9 1.3 1.8 2.0 4.5 4.8 3.4 0.0 1.4 1.1 4.9 0.6 2.9 4.5 2.2 4.7 3.4 11.6 1.1 1.9 3.6 2.7 2.6 0.3 1.0 1.0 19.1 13.5 8.6 2.9 3.7 2.0 4.3 1.7 5.7 12.3 4.6 1.9 19.2 6.2 6.5 4.5 3.7 0.0 0.0 6.8 5.1 4.5 6.2 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 PRKCG "MGC57564, PKCC, PKCG, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 49.9" "Cell line enhanced" "Detected in some" "A549: 5.8;HAP1: 2.7;SH-SY5Y: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013051, HPA047870, HPA054560" Enhanced "CAB013051: AB_2533015, HPA047870: , HPA054560: " "unprognostic (7.14e-2)" "unprognostic (5.42e-2)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-2)" "unprognostic (7.48e-3)" "unprognostic (2.68e-1)" "unprognostic (2.22e-7)" "unprognostic (2.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" 1.0 0.9 28.0 1.1 49.9 2.2 0.9 12.1 39.2 0.9 1.3 1.6 0.0 1.5 1.0 0.9 1.0 1.4 1.0 0.9 49.7 4.4 0.9 0.9 1.0 0.9 2.9 20.8 0.9 3.5 2.1 0.2 0.9 0.7 0.9 1.2 0.0 0.9 1.0 1.0 0.9 1.3 1.1 1.4 0.9 1.8 4.4 2.1 1.3 0.9 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 5.8 1.3 0.0 0.0 0.2 0.1 0.7 0.4 0.1 0.0 1.5 1.5 0.3 1.7 0.0 0.5 2.7 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.1 1.0 0.5 1.0 0.6 0.1 1.1 0.0 0.0 4.0 1.6 0.2 0.0 1.9 0.0 1.0 0.0 2.0 0.0 0.0 1.7 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 49.9 12.1 28.5 49.7 4.4 2.9 20.8 0.7 2.1 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 29.9;HUVEC TERT2: 39.2;MOLT-4: 26.0;RT4: 16.5;TIME: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "gdT-cell: 30.0;MAIT T-cell: 23.9;memory CD4 T-cell: 23.0;memory CD8 T-cell: 35.3;naive CD4 T-cell: 28.5;naive CD8 T-cell: 27.6;NK-cell: 27.3;T-reg: 18.6" "Group enriched" "Detected in many" 14 "NK-cells: 27.3;T-cells: 35.3" "Group enriched" "Detected in many" 6 "basal ganglia: 25.0;thalamus: 19.5" "Low region specificity" "Detected in many" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: " "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favourable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 17.5 5.4 5.0 21.6 22.0 11.2 14.7 2.8 6.1 13.6 10.3 6.2 6.9 5.1 19.1 7.0 20.1 8.6 12.7 10.1 6.8 4.4 8.1 5.5 24.1 27.6 5.9 2.5 7.1 5.9 8.8 15.5 22.7 7.2 9.8 5.0 9.1 24.7 10.8 9.1 15.9 16.0 10.5 5.7 25.9 6.0 4.3 6.4 54.6 15.1 10.6 34.6 13.2 14.4 0.4 2.2 1.5 0.7 27.3 35.3 17.9 6.2 2.2 0.3 1.7 1.0 0.2 29.9 0.1 0.5 0.3 0.3 0.6 3.7 0.1 4.5 0.0 4.4 0.2 4.8 0.5 0.7 2.8 0.0 0.7 0.2 0.4 0.0 0.9 0.8 5.0 0.2 3.4 39.2 0.0 0.1 2.2 11.5 26.0 0.2 0.5 3.0 2.2 1.1 0.0 0.0 16.5 1.1 1.9 0.7 5.8 3.6 5.7 0.5 25.7 0.7 5.2 0.7 0.3 0.5 0.1 0.2 1.1 0.3 1.2 0.1 0.7 0.5 30.0 0.4 23.9 0.4 23.0 35.3 2.2 0.3 28.5 27.6 1.5 27.3 0.2 0.7 18.6 17.9 5.0 22.0 2.8 6.1 6.8 4.4 5.9 2.5 7.2 6.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: " "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favourable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 35.9 9.1 9.2 9.8 8.2 11.4 14.9 9.2 13.7 12.3 13.3 13.3 17.6 11.0 30.5 13.0 16.9 17.3 18.1 21.1 8.0 10.7 10.2 11.6 7.4 13.0 9.2 4.6 10.2 12.7 10.4 16.5 9.5 11.2 9.1 12.3 12.4 13.3 3.6 19.3 10.2 9.6 14.2 18.2 19.3 11.0 14.6 11.9 20.0 26.3 9.0 28.9 6.3 10.1 12.8 9.9 11.9 15.2 15.7 15.1 15.7 9.2 7.2 5.0 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell line enhanced" "Detected in some" "HEL: 30.9;MOLT-4: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" 200000 "Centriolar satellite" "HPA065279: , HPA073098: " "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 1.8 3.3 0.0 0.0 2.1 30.9 0.0 0.2 0.4 1.5 0.3 0.1 2.0 0.1 0.1 0.3 6.7 0.0 0.0 0.0 23.2 4.3 3.2 0.0 4.5 0.7 0.0 6.5 1.6 0.2 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435288-11450968 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" 62000000 "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: , HPA043560: " "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavourable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 46.9 37.4 26.9 32.5 28.5 50.9 45.0 37.8 39.4 46.8 42.6 36.3 50.1 43.6 50.1 48.4 41.2 50.2 50.2 31.5 27.7 27.3 41.2 85.6 39.9 53.2 29.6 32.1 72.6 77.7 52.9 40.3 72.7 27.0 48.8 38.4 43.9 58.8 53.1 31.3 43.8 41.8 40.1 38.6 42.5 37.9 42.8 29.8 51.6 60.1 32.7 41.9 44.6 44.9 26.2 44.1 32.8 29.8 19.5 28.5 19.4 48.6 34.2 38.0 63.6 65.1 84.4 39.5 52.4 71.6 61.5 58.1 49.9 54.8 31.3 85.0 72.1 48.5 39.1 57.1 49.8 33.6 25.1 27.2 42.9 43.2 48.7 42.4 40.0 77.0 42.7 57.7 45.6 42.1 31.4 71.0 53.1 71.8 33.0 49.0 79.9 44.2 35.3 34.7 79.7 42.8 42.6 24.1 47.5 45.8 47.7 42.9 49.0 47.0 42.4 74.7 35.3 70.8 61.4 87.4 103.9 21.8 57.1 44.6 50.9 15.9 29.8 23.8 24.9 22.2 28.5 23.9 21.0 23.8 22.6 26.2 20.3 21.3 32.8 19.5 24.4 44.1 22.0 19.4 26.9 28.5 37.8 39.4 27.7 27.3 29.6 32.1 27.0 29.8 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Cell line enhanced" "Detected in many" "BEWO: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favourable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.5 4.8 1.7 8.9 0.0 0.0 23.5 0.5 0.2 5.6 0.3 12.1 16.4 0.0 14.9 1.9 13.2 10.1 12.5 4.0 0.5 11.2 0.0 7.7 16.1 1.6 0.0 5.8 0.3 7.5 0.0 4.3 0.0 3.3 0.1 0.1 9.2 0.4 0.0 3.4 11.7 0.0 0.0 2.6 9.6 7.9 12.3 9.9 6.1 13.7 2.6 9.6 2.0 0.0 0.0 7.1 0.1 0.0 3.5 0.6 0.1 0.6 0.1 8.5 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;fHDF/TERT166: 19.0;HSkMC: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favourable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavourable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.0 17.8 16.7 0.1 12.1 9.3 12.4 6.7 0.0 0.5 0.0 1.2 19.0 0.1 5.9 1.4 6.8 0.0 4.1 0.0 0.1 0.4 9.0 0.0 0.1 17.7 0.6 0.8 1.4 2.5 1.2 0.4 11.6 1.3 0.0 0.0 2.5 6.2 0.0 7.0 3.2 13.2 5.6 3.6 7.1 2.1 0.0 4.7 0.0 0.1 6.3 11.7 4.8 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favourable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.6 13.4 5.3 6.5 4.4 3.6 6.8 4.5 7.1 9.4 10.3 7.4 8.5 10.1 7.9 6.0 12.9 4.7 12.0 2.9 8.6 7.0 10.6 4.2 3.9 5.8 7.7 15.7 4.3 5.8 5.4 4.6 16.5 6.8 14.6 3.9 9.1 14.8 25.0 4.5 6.8 9.7 2.5 16.3 5.8 12.9 3.4 10.8 8.4 7.0 1.8 5.6 3.1 7.8 4.0 8.0 3.4 3.6 14.3 56.9 5.0 4.2 6.4 4.2 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favourable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.6 5.4 14.3 11.8 10.9 18.4 10.5 8.2 15.3 9.3 9.5 8.6 4.5 18.6 6.9 12.3 5.0 9.7 10.1 12.6 24.0 14.2 12.2 8.3 5.8 4.5 8.7 7.5 8.6 5.2 14.7 9.7 16.5 10.2 22.9 10.8 2.1 3.8 6.8 15.1 5.2 12.8 22.6 15.9 6.2 14.3 10.8 28.0 7.9 4.5 48.2 4.9 8.0 15.9 26.7 13.9 10.6 9.2 26.2 48.5 21.7 9.3 3.7 16.0 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: " "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.4 27.8 27.1 25.7 16.9 17.9 11.5 13.8 13.6 19.5 19.2 18.1 10.7 31.0 12.0 16.9 18.5 35.8 18.9 30.6 6.8 22.2 60.9 25.0 22.2 7.3 23.1 12.7 12.9 6.2 30.7 32.2 20.0 40.5 13.1 21.4 15.2 32.6 19.1 29.8 8.4 16.0 21.3 10.9 9.8 28.0 13.6 17.3 42.6 13.9 13.4 19.9 16.0 23.2 25.5 21.7 20.1 27.7 11.5 14.6 44.6 14.4 26.3 20.6 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 PRKG1 "PGK, PKG, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase, cGMP-dependent, type I" Q13976 10 50990891-52298350 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 11.3;BJ hTERT+: 15.5;fHDF/TERT166: 12.9;U-138 MG: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "basophil: 8.0" "Lineage enriched" "Detected in single" 24 "granulocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol 33000 "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 8.0 10.9 5.2 6.6 7.3 0.8 6.9 2.8 5.4 19.2 14.4 2.1 6.8 2.9 22.8 10.7 6.0 9.9 12.6 14.8 7.0 4.9 4.4 2.1 19.5 2.6 3.1 4.8 8.9 2.6 13.7 8.4 11.0 4.6 9.5 6.2 6.2 6.4 9.4 24.9 2.8 5.3 28.2 2.7 2.7 5.9 5.0 3.1 0.2 9.2 12.7 1.2 13.4 15.8 0.1 0.1 8.0 0.1 0.3 0.0 0.1 0.0 0.1 1.4 11.3 5.4 5.2 0.0 4.9 15.5 1.6 2.3 0.1 0.7 0.2 0.0 12.9 0.1 0.0 0.0 1.4 0.0 4.2 0.8 0.3 0.0 4.7 0.0 0.0 6.6 0.0 4.1 0.1 0.0 0.0 0.1 4.3 0.1 0.0 0.0 3.2 1.9 0.0 3.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.0 9.5 1.7 4.8 2.9 1.2 0.5 0.0 8.4 0.0 2.0 8.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 5.2 7.3 2.8 5.4 7.0 4.9 3.1 4.8 4.6 3.1 PRKG2 "cGKII, PRKGR2" ENSG00000138669 "Protein kinase, cGMP-dependent, type II" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.3" "Cell line enhanced" "Detected in some" "ASC diff: 5.1;ASC TERT1: 3.9;HEL: 20.3;hTCEpi: 4.0;SCLC-21H: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 4.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.0;MAIT T-cell: 2.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 2.2" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 4.7 0.4 5.2 0.4 2.9 0.6 2.2 0.8 5.3 1.4 7.7 1.2 0.7 12.2 0.6 0.6 3.8 0.6 0.4 6.3 2.9 3.3 0.7 0.3 4.3 0.3 2.5 1.9 0.3 1.8 0.0 12.1 0.2 9.3 12.7 3.8 1.4 0.8 4.6 0.3 2.1 34.3 0.7 1.3 0.3 1.3 1.7 2.4 0.0 1.3 0.0 0.6 1.2 1.3 0.4 0.0 2.0 0.0 0.4 2.2 0.4 0.1 0.3 0.1 0.0 5.1 3.9 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.2 0.9 0.1 0.3 1.5 0.0 0.4 0.0 20.3 0.6 0.0 0.0 0.0 0.0 0.5 4.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.1 0.0 0.8 6.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 2.2 0.2 0.5 0.3 0.0 0.4 0.8 0.9 0.0 0.4 0.0 0.0 0.0 0.4 5.2 2.9 0.8 5.3 2.9 3.3 2.5 1.9 9.3 2.4 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347420-162727771 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.8" "Cell line enhanced" "Detected in some" "AN3-CA: 3.6;HEL: 9.0;Karpas-707: 5.7;RPMI-8226: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: " "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favourable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 6.8 7.1 7.9 2.3 12.2 1.5 4.2 7.2 13.4 5.3 4.3 6.3 4.6 2.8 7.8 4.4 6.1 3.4 4.3 17.7 9.2 6.2 17.4 3.6 2.6 3.0 5.8 5.2 6.4 3.0 5.6 8.6 2.0 5.5 4.0 2.4 8.3 3.5 4.8 41.8 4.0 3.3 6.6 5.9 2.7 3.5 10.3 6.8 0.6 3.8 4.7 2.7 4.9 2.1 4.6 1.2 4.2 0.8 1.8 4.6 1.3 0.0 0.3 1.2 3.6 0.9 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 9.0 0.2 0.0 0.8 0.2 0.1 3.1 0.1 0.0 0.5 0.0 0.4 5.7 0.9 0.5 0.1 0.1 0.2 0.8 0.0 0.0 5.7 0.6 0.1 0.9 2.5 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.3 0.1 0.3 0.8 0.1 0.0 0.1 0.1 2.2 2.8 0.8 4.2 2.1 0.5 3.5 1.5 2.0 2.2 1.2 4.6 4.4 4.6 1.5 1.8 0.4 0.3 0.2 1.3 7.9 12.2 7.2 11.7 9.2 6.2 5.8 5.2 5.5 6.8 PRKX PKX1 ENSG00000183943 "Protein kinase, X-linked" P51817 X 3604370-3713608 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 4.3 1.3 12.3 7.5 15.8 5.4 11.2 4.4 12.3 6.9 5.2 5.4 11.5 4.1 7.3 8.4 13.6 16.5 3.9 4.0 14.0 7.4 14.2 2.0 8.4 9.5 27.9 5.6 4.8 4.1 3.2 2.3 6.6 22.7 3.7 5.2 3.1 6.5 5.3 1.6 9.9 6.0 3.0 17.6 10.0 3.1 6.1 22.7 6.1 28.8 3.2 8.0 3.7 11.2 2.5 2.8 12.2 4.1 3.3 3.8 1.7 4.5 4.2 11.6 8.6 2.2 3.0 10.6 2.7 1.0 1.3 1.8 6.2 3.1 0.4 2.7 2.1 3.1 10.8 8.1 2.3 5.0 7.5 5.0 3.2 0.1 2.3 6.4 38.9 2.0 8.7 1.4 5.4 13.1 5.8 6.5 4.4 3.9 7.3 5.8 7.7 4.8 13.7 11.1 8.5 10.7 3.8 7.8 5.0 2.8 1.8 2.7 1.4 5.1 7.1 1.2 2.0 1.9 1.8 0.1 0.3 5.8 0.7 5.8 3.0 12.2 3.1 1.8 3.5 3.3 3.8 2.5 3.7 3.3 2.3 2.4 3.1 3.3 0.8 3.3 4.1 2.8 2.5 1.7 12.3 15.8 4.4 12.3 14.0 7.4 27.9 5.6 22.7 22.7 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890730-60906588 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 20.5 32.2 33.6 27.0 37.9 32.0 28.9 49.6 61.8 30.4 30.6 21.3 24.5 24.2 27.1 21.4 36.7 34.9 20.1 18.0 32.8 46.3 21.5 39.4 18.0 33.1 35.0 50.0 41.3 31.3 45.7 37.6 24.9 46.2 37.7 31.5 21.5 28.8 30.9 31.9 39.0 24.6 28.8 23.7 28.3 23.7 15.2 24.4 46.3 25.3 24.4 41.7 24.8 24.8 3.1 5.3 4.4 11.8 2.4 3.3 1.2 43.8 34.3 38.6 27.5 22.6 19.9 35.0 23.9 32.5 48.1 36.2 37.7 33.2 63.6 32.2 22.9 40.3 54.2 43.1 37.4 43.3 34.6 52.9 27.2 40.4 32.8 69.9 37.8 21.1 32.8 36.9 41.6 37.3 52.5 36.8 23.5 61.8 70.5 52.6 68.2 46.3 62.7 39.5 49.8 24.3 28.8 32.9 39.6 29.6 49.3 39.8 51.5 38.7 23.3 21.3 34.3 37.1 38.6 32.9 46.0 64.0 26.5 48.0 32.0 4.4 11.8 2.6 3.2 5.4 2.6 1.3 2.6 2.3 4.8 3.1 3.3 3.0 0.7 2.4 2.9 5.3 2.2 1.2 33.6 37.9 49.6 61.8 32.8 46.3 35.0 50.0 46.2 24.4 PRPF4 "HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60" ENSG00000136875 "Pre-mRNA processing factor 4" O43172 9 113275343-113292905 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021794, HPA022248" Enhanced Enhanced "Nuclear speckles" "Nuclear speckles" "HPA021794: AB_1855772, HPA022248: AB_1855773" "unprognostic (1.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (3.70e-3)" "prognostic unfavourable (9.35e-4)" "unprognostic (1.95e-2)" "unprognostic (6.57e-2)" "unprognostic (3.14e-2)" "unprognostic (5.00e-2)" "unprognostic (6.76e-3)" "unprognostic (2.18e-3)" "unprognostic (4.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" 16.4 20.9 13.8 23.8 17.4 18.4 21.7 19.4 23.2 15.2 15.7 14.4 20.0 13.4 18.9 28.6 22.9 17.8 17.6 16.8 15.3 13.9 21.5 24.3 15.2 19.6 12.4 19.2 24.3 22.7 19.1 19.6 17.2 19.0 20.6 17.6 13.9 16.8 19.7 26.1 21.8 14.7 21.1 14.4 18.7 15.9 16.6 12.6 21.8 16.5 18.2 23.1 18.0 24.6 16.5 19.9 18.1 21.7 17.0 17.9 13.7 12.8 22.1 14.7 16.2 10.4 10.8 15.0 20.2 10.1 22.3 16.4 21.5 12.0 26.8 11.9 10.9 29.7 30.8 17.7 25.2 19.0 11.6 13.6 19.3 15.7 9.5 23.9 12.5 7.8 12.2 23.2 22.5 10.6 23.3 14.9 19.0 20.0 22.3 17.1 23.4 24.3 20.8 35.3 18.4 9.7 10.5 19.4 13.1 29.5 16.0 9.3 25.0 12.5 10.4 18.2 13.8 23.4 25.6 19.2 51.9 26.3 14.0 15.4 23.3 18.1 15.8 15.1 15.2 19.3 17.9 16.5 15.2 13.8 19.9 16.4 15.5 15.3 5.3 17.0 21.7 13.1 13.6 13.7 13.8 17.4 19.4 23.2 15.3 13.9 12.4 19.2 19.0 12.6 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavourable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favourable (6.82e-5)" 23.2 21.6 19.6 24.0 20.5 8.5 21.4 35.6 26.8 18.3 19.3 6.0 14.7 12.0 22.2 14.2 23.6 14.7 13.6 16.3 16.5 11.7 15.0 14.5 13.0 15.4 14.5 14.1 19.1 14.4 20.9 30.9 17.1 21.0 14.9 15.7 5.3 22.7 20.4 45.7 16.3 16.4 14.9 23.7 19.0 13.6 11.6 20.2 21.8 21.1 11.3 17.4 21.4 22.2 9.7 13.6 7.5 11.9 11.8 9.1 3.9 14.4 12.6 19.8 13.6 11.3 10.5 9.6 14.1 15.5 15.4 15.5 12.0 7.3 23.8 17.8 15.8 13.0 25.0 12.2 22.1 11.1 18.3 26.7 14.4 10.7 8.7 29.4 14.6 9.6 8.1 10.9 6.8 15.3 36.5 8.8 15.0 8.5 21.6 9.9 11.9 11.7 24.5 19.2 23.0 9.8 16.4 15.4 10.1 16.3 10.2 12.4 15.9 14.8 16.3 15.1 8.7 9.9 13.6 10.0 15.6 27.7 8.3 13.5 18.4 7.5 11.9 3.6 7.6 9.9 9.1 9.7 8.6 9.0 10.2 9.3 8.0 8.0 6.1 11.8 8.7 13.6 6.3 3.9 19.6 20.5 35.6 26.8 16.5 11.7 14.5 14.1 21.0 20.2 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease mutation, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell line enhanced" "Detected in many" "AF22: 19.9;REH: 15.2;U-138 MG: 13.7" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "NK-cell: 7.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 7.3" "HPA014447, HPA019203" Enhanced Supported "Plasma membrane" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 3.7 7.2 27.2 2.8 40.5 0.8 2.1 86.7 53.6 10.1 6.0 6.0 3.1 6.2 20.7 8.3 4.4 10.2 10.3 5.3 18.9 13.0 2.1 0.9 5.7 3.5 5.5 33.2 35.7 2.4 8.6 17.6 7.1 18.0 16.2 2.6 5.2 4.6 14.4 4.3 3.1 6.8 10.3 7.4 1.8 7.3 9.9 10.2 0.0 2.8 0.3 1.6 5.1 10.7 0.2 0.0 0.5 0.2 7.3 0.6 0.3 0.3 1.2 19.9 7.4 1.0 3.8 0.5 2.4 4.0 0.8 0.9 1.1 2.3 0.2 0.5 3.3 2.0 2.7 0.4 0.3 5.3 1.6 1.3 8.9 0.8 0.2 0.0 0.3 3.4 0.1 1.4 0.1 1.0 0.2 1.6 0.6 3.3 0.5 0.6 5.7 1.0 15.2 1.1 0.4 0.1 0.7 4.3 4.5 0.2 2.9 0.4 7.4 0.1 1.1 13.7 4.8 0.8 1.3 3.4 0.4 0.1 5.4 0.1 0.5 0.5 0.0 0.1 0.2 0.1 0.3 0.1 0.6 0.4 0.0 0.2 0.4 0.2 0.2 7.3 0.2 0.0 0.1 0.3 27.2 40.5 86.7 53.6 18.9 13.0 5.5 33.2 18.0 10.2 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053927 Approved Approved Nucleoplasm Nucleoplasm "HPA053927: AB_2682312" "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favourable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.3 13.1 14.9 16.5 23.3 11.8 9.7 8.8 13.5 9.4 8.4 9.9 10.6 6.9 13.5 14.9 11.2 8.6 9.1 3.2 2.7 9.6 7.9 9.7 12.5 16.0 7.5 4.8 21.7 15.8 11.1 11.8 13.7 12.0 3.0 9.7 16.4 10.2 4.8 14.3 8.2 15.7 5.7 14.3 11.1 9.2 13.0 15.5 27.4 7.5 9.0 13.8 13.7 12.0 10.6 3.8 8.8 4.4 9.1 4.8 14.9 12.8 5.1 11.6 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell line enriched" "Detected in single" 18 "HEL: 13.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040348, HPA043932" Approved Supported Mitochondria Mitochondria "HPA040348: , HPA043932: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.0 12.5 1.5 10.0 11.6 8.9 4.3 13.0 12.3 13.0 12.4 20.7 11.8 15.9 14.4 9.7 18.9 10.3 13.5 13.9 19.4 31.0 7.3 25.6 26.0 17.0 14.2 9.7 8.8 15.3 6.1 18.7 9.2 18.6 12.2 9.5 41.6 12.1 18.3 9.3 23.2 22.2 8.4 13.5 15.6 14.1 9.3 11.4 19.7 7.2 11.7 33.5 15.3 9.9 9.7 14.8 15.6 19.5 18.6 12.4 10.8 7.6 12.3 5.8 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain "HPA021223: AB_1845798" "unprognostic (6.58e-2)" "unprognostic (7.01e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (3.90e-2)" "unprognostic (1.74e-1)" "unprognostic (6.58e-3)" "unprognostic (8.67e-2)" "unprognostic (4.08e-2)" "unprognostic (5.98e-3)" "unprognostic (5.74e-4)" "unprognostic (1.38e-2)" "unprognostic (1.91e-1)" "unprognostic (1.72e-2)" 14.9 15.0 12.5 8.3 11.9 7.1 9.1 3.9 13.7 9.4 7.8 10.7 12.9 7.7 7.8 16.1 7.8 9.9 12.6 13.1 10.7 9.4 14.5 19.3 7.5 14.7 11.6 8.5 6.2 24.7 8.8 11.0 7.2 8.9 9.9 4.0 8.3 9.3 9.9 13.0 15.1 5.8 6.4 6.2 9.4 12.4 16.1 6.2 7.1 18.8 9.1 5.7 9.4 5.6 8.7 11.4 5.6 14.4 10.5 29.4 12.8 15.7 7.1 1.6 4.3 2.3 3.0 12.4 10.5 2.9 4.0 2.2 3.6 6.0 6.0 14.2 4.3 17.5 1.3 7.6 1.2 8.6 2.4 2.6 8.8 7.1 6.8 3.9 7.1 2.5 8.0 4.9 5.1 8.0 6.7 4.8 4.6 14.5 7.0 5.8 2.2 32.0 6.0 3.5 13.5 7.3 3.5 7.0 6.5 11.3 13.6 7.9 12.2 2.5 9.5 5.9 8.1 20.8 6.5 14.3 7.6 3.9 7.9 3.0 7.0 2.5 13.2 5.6 29.3 14.4 29.3 8.7 15.1 29.4 11.4 7.2 11.1 25.5 1.7 10.5 7.5 10.4 14.2 12.8 12.5 11.9 3.9 13.7 10.7 9.4 11.6 8.5 8.9 6.2 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 15.9 22.9 17.1 12.4 17.1 9.9 20.7 12.5 22.1 15.6 17.2 11.8 16.3 11.6 14.3 36.7 16.4 13.8 13.1 12.6 19.3 17.8 14.8 34.7 12.1 12.5 16.7 15.2 14.2 19.9 10.3 18.3 13.6 21.0 15.9 20.7 8.1 13.7 18.7 23.3 11.4 11.0 16.8 17.1 15.5 14.3 15.7 18.1 9.0 11.8 13.5 16.9 13.0 10.5 15.6 21.6 12.6 29.3 13.1 15.5 13.0 19.8 37.9 12.2 11.1 23.2 20.0 13.1 19.1 16.9 16.4 24.0 24.4 15.6 14.4 29.0 16.0 19.8 26.2 24.6 23.9 27.7 35.7 25.7 19.7 44.8 35.8 22.7 14.6 22.5 32.1 25.4 29.6 27.2 28.6 16.1 24.3 47.9 19.4 18.5 10.5 30.0 10.6 20.5 21.0 27.3 28.6 15.8 20.5 9.9 10.8 23.4 25.2 16.2 17.9 21.4 21.7 12.8 20.7 20.9 23.2 21.4 14.1 14.2 16.3 1.9 25.8 1.1 9.2 24.4 12.4 15.6 10.8 10.4 18.5 13.1 15.5 11.1 12.6 13.1 29.3 21.6 12.3 13.0 17.1 17.1 12.5 22.1 19.3 17.8 16.7 15.2 21.0 18.1 PUS1 ENSG00000177192 "Pseudouridylate synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA051636: , HPA057593: " "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavourable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" 12.7 15.8 18.8 19.5 23.3 26.2 11.2 8.8 16.9 8.7 11.9 9.4 11.0 12.4 13.6 18.7 16.5 12.9 25.1 8.6 15.6 8.3 10.7 22.8 11.0 21.4 11.7 15.8 10.1 19.8 7.2 9.5 8.3 11.7 11.7 10.5 7.6 11.4 15.7 13.5 15.4 13.9 9.7 6.2 17.4 13.6 11.9 16.4 11.6 10.3 11.6 15.8 10.8 12.8 5.9 4.6 1.9 2.0 9.1 4.0 1.3 15.2 20.0 4.7 8.4 4.6 7.9 29.2 11.8 5.0 9.0 5.8 22.1 10.0 18.3 13.7 6.4 19.4 15.6 11.2 5.9 8.1 31.6 18.4 9.7 19.3 12.4 31.4 16.9 7.9 9.1 10.3 8.8 8.8 22.8 5.6 5.2 26.6 20.6 28.2 25.1 30.5 19.7 6.8 18.9 7.3 21.3 13.3 7.4 9.9 13.6 10.9 14.9 34.0 7.7 7.2 15.4 15.3 17.1 15.5 11.6 21.7 7.4 25.2 9.9 1.2 2.0 0.4 3.2 1.4 2.2 5.9 2.7 3.3 1.6 5.5 4.0 2.1 1.9 9.1 1.3 4.6 2.4 1.3 18.8 23.3 8.8 16.9 15.6 8.3 11.7 15.8 11.7 16.4 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37344574-37373322 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.6;blood: 137.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.5;SCLC-21H: 23.8;SK-MEL-30: 80.0;U-266/84: 62.5" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "neutrophil: 137.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 3.2 77.6 4.3 5.4 5.8 17.0 6.4 1.2 11.6 9.2 11.3 2.2 1.5 2.2 6.2 43.7 2.4 1.9 5.5 2.9 6.7 17.9 12.4 1.3 6.1 7.4 3.9 5.0 1.4 5.5 9.6 31.6 7.8 5.9 3.5 4.2 21.2 14.7 2.8 4.0 14.2 2.3 3.4 3.0 8.5 3.4 2.6 0.5 2.3 1.8 4.4 4.8 7.0 2.9 0.2 10.7 137.6 29.7 0.0 0.0 12.1 0.1 7.9 0.0 0.0 1.0 2.6 0.0 1.0 17.5 1.3 2.1 0.5 1.4 0.0 0.6 5.9 0.0 0.5 0.0 2.1 0.1 15.3 3.5 0.0 1.5 0.1 0.5 0.0 1.5 0.0 9.7 0.0 5.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.0 0.0 0.1 8.6 2.1 23.8 0.0 1.3 0.0 80.0 0.1 0.5 3.7 0.0 0.0 0.0 0.1 3.0 62.5 0.0 5.3 0.0 0.0 0.6 29.7 0.2 0.0 3.4 0.0 0.2 0.0 0.0 10.7 0.1 0.0 0.0 137.6 0.0 0.3 0.2 0.0 12.1 4.3 5.8 1.2 11.6 6.7 17.9 3.9 5.0 5.9 0.5 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria Mitochondria "HPA042695: , HPA048651: , HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favourable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favourable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favourable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavourable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 14.0 18.4 20.6 13.4 29.1 14.2 11.5 18.0 21.3 11.3 14.5 13.3 19.4 12.8 15.3 11.6 14.6 15.8 13.5 19.5 19.7 13.1 11.8 18.9 8.4 13.5 22.9 19.3 22.1 33.9 5.8 12.0 9.8 19.9 13.7 6.6 10.5 26.6 12.7 20.5 12.6 14.2 13.3 12.7 11.5 12.5 5.0 22.2 5.3 19.0 11.9 10.3 12.0 10.3 19.6 19.1 0.9 14.4 18.5 18.8 10.4 17.1 13.9 6.6 19.3 6.9 8.4 8.6 8.8 7.9 10.3 10.2 11.0 6.6 19.4 21.7 5.0 11.6 6.0 10.6 3.4 11.4 8.3 12.8 5.6 23.3 12.1 18.9 11.3 12.4 9.1 6.7 9.8 10.5 14.0 22.4 5.1 26.9 16.3 23.7 17.4 21.5 17.2 8.8 30.0 8.4 11.0 21.5 9.3 13.5 14.8 11.5 9.4 8.0 8.1 15.9 8.8 25.4 20.5 24.7 19.0 9.5 8.6 23.1 19.2 0.9 8.3 0.2 15.1 14.4 18.8 19.6 16.3 13.1 16.4 19.0 17.5 13.9 0.6 18.5 7.3 19.1 17.7 10.4 20.6 29.1 18.0 21.3 19.7 13.1 22.9 19.3 19.9 22.2 QTRT2 "FLJ12960, QTRTD1" ENSG00000151576 "Queuine tRNA-ribosyltransferase accessory subunit 2" Q9H974 3 114005833-114088422 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036827, HPA036828" Uncertain Approved "Nucleoplasm,Intermediate filaments" Nucleoplasm "Intermediate filaments" "HPA036827: , HPA036828: AB_10696788" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (6.71e-3)" "unprognostic (1.01e-3)" "unprognostic (8.57e-2)" "unprognostic (4.41e-1)" "unprognostic (5.82e-3)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" "unprognostic (6.94e-2)" "unprognostic (6.48e-3)" "prognostic unfavourable (6.95e-4)" "unprognostic (1.44e-1)" "unprognostic (8.74e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (1.18e-3)" 17.1 13.9 8.7 12.4 10.4 13.3 14.1 6.4 10.3 11.0 11.2 14.9 7.9 10.4 16.1 9.2 13.7 13.1 13.6 7.5 6.7 6.7 15.8 15.7 12.2 14.9 11.0 7.6 12.6 15.3 10.7 16.9 11.6 9.4 11.2 12.5 17.7 11.8 9.8 7.5 12.4 12.9 10.8 11.3 19.9 10.7 14.1 10.0 17.3 13.2 10.9 21.6 11.6 10.9 13.9 15.8 5.3 12.9 6.4 6.6 5.0 13.3 13.9 11.6 12.8 5.1 6.3 11.0 7.0 4.4 12.0 11.1 13.2 9.7 24.9 10.3 6.4 13.4 22.5 10.6 15.8 4.7 10.2 11.2 8.3 9.4 7.3 20.3 10.5 4.9 9.6 10.9 15.6 12.4 11.7 8.9 6.8 10.6 16.9 7.9 22.2 15.2 15.4 8.2 13.3 9.4 9.3 15.8 7.5 10.2 10.1 12.9 11.2 10.3 8.1 10.5 11.5 4.1 13.6 6.3 9.1 34.8 9.2 15.0 21.1 0.3 12.4 2.9 5.6 12.9 5.3 13.9 4.8 5.5 15.8 9.5 6.6 5.3 5.3 6.4 9.1 6.6 5.9 5.0 8.7 10.4 6.4 10.3 6.7 6.7 11.0 7.6 9.4 10.0 RAD18 RNF73 ENSG00000070950 "RAD18, E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA006716: , HPA006724: , HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavourable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavourable (3.73e-4)" "prognostic unfavourable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 6.2 5.7 7.4 5.6 12.7 7.9 9.5 16.4 11.4 5.5 6.6 3.9 5.4 17.7 6.5 3.7 7.6 4.9 5.6 4.4 4.7 3.3 4.3 5.7 5.9 7.6 8.4 6.9 7.1 4.2 3.4 6.9 6.9 5.7 7.4 9.0 3.5 7.5 3.5 3.7 8.5 10.5 6.0 7.8 8.5 5.1 9.5 9.8 16.6 6.7 4.7 7.5 6.1 6.8 3.7 6.3 8.7 3.0 4.3 5.5 1.5 9.7 9.3 7.8 4.6 1.9 4.2 9.5 15.5 5.3 15.0 10.3 8.4 6.3 12.1 3.0 8.8 3.4 8.2 8.0 15.3 7.4 10.3 10.3 9.3 5.0 1.2 13.5 8.9 1.5 2.9 14.8 10.1 4.8 10.9 12.0 13.0 11.3 13.7 9.6 10.8 17.1 10.9 8.6 9.5 4.3 7.5 3.2 7.4 6.9 6.6 5.0 6.9 6.0 4.0 12.4 6.8 10.6 13.2 6.1 9.3 26.3 9.2 15.0 9.1 7.4 2.7 8.7 3.0 3.0 5.5 3.7 4.0 5.2 3.4 3.7 4.3 3.2 1.2 4.3 1.8 6.3 5.0 1.5 7.4 12.7 16.4 11.4 4.7 3.3 8.4 6.9 5.7 9.8 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.1 17.4 26.6 20.5 23.1 18.7 53.5 23.1 39.2 30.6 34.8 13.6 12.5 15.9 11.1 35.8 9.7 28.0 20.5 31.9 27.7 21.9 21.4 21.0 12.6 23.4 20.8 20.3 17.2 20.7 31.5 25.6 21.9 15.5 41.8 29.5 25.9 26.7 15.3 27.0 23.7 21.6 23.4 20.0 18.3 22.9 8.3 17.5 18.9 18.3 12.3 30.4 27.5 15.7 21.1 20.1 17.6 25.7 32.6 51.8 34.2 18.2 24.3 22.4 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510709-36593156 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "lymphoid tissue: 462.4" "Group enriched" "Detected in some" 110 "MOLT-4: 65.8;REH: 62.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043939 Supported Nucleoplasm Nucleoplasm "HPA043939: " "unprognostic (7.35e-2)" "unprognostic (1.57e-3)" "unprognostic (8.75e-2)" "unprognostic (3.44e-1)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "unprognostic (2.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (5.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.16e-9)" "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-4)" "unprognostic (1.53e-1)" 0.7 2.3 0.5 0.5 0.5 7.4 0.7 0.5 0.5 0.5 0.6 0.5 0.5 1.2 0.5 1.3 0.5 0.6 0.5 0.6 0.5 0.2 2.4 1.2 0.8 0.5 0.5 0.5 0.6 1.1 1.9 0.5 0.8 0.5 0.5 0.4 0.5 1.5 0.5 0.5 0.2 1.5 0.5 0.5 4.4 0.8 0.9 0.5 462.4 4.5 0.5 0.8 0.7 0.5 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 65.8 0.0 0.5 0.0 62.9 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.5 0.5 0.5 0.5 0.2 0.5 0.5 0.5 0.5 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA replication, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: , HPA043544: " "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 15.1 17.6 17.2 14.0 16.4 81.4 17.9 33.0 15.7 17.8 18.8 16.3 19.8 10.2 23.2 18.7 15.3 21.2 17.6 14.7 15.0 13.2 13.1 15.8 15.7 18.1 18.7 12.2 27.2 14.4 20.7 23.1 73.9 15.4 18.2 14.4 18.4 13.7 14.7 19.2 19.2 16.4 18.4 19.2 18.6 16.4 25.1 18.7 24.3 18.6 11.8 15.5 17.9 17.9 3.8 6.9 8.5 3.7 6.5 4.2 1.0 17.6 9.2 21.8 22.6 16.7 17.4 23.6 14.3 13.2 13.1 14.2 10.2 14.3 24.5 10.8 12.1 17.0 23.3 12.5 21.7 13.4 18.1 21.1 26.5 29.0 13.0 28.0 12.6 15.1 17.4 17.0 20.1 18.7 26.5 22.4 15.1 18.1 22.6 25.3 25.0 8.8 31.1 22.1 21.6 12.6 15.8 17.5 15.3 20.1 18.1 25.3 14.1 24.9 16.2 16.3 12.0 14.0 15.3 20.0 19.8 30.9 13.1 18.6 13.4 8.5 2.3 3.7 4.0 3.7 4.2 3.8 4.1 2.8 1.6 3.8 3.5 4.0 5.0 6.5 2.1 6.9 3.1 1.0 17.2 16.4 33.0 15.7 15.0 13.2 18.7 12.2 15.4 18.7 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favourable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favourable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favourable (7.89e-5)" 8.8 12.1 15.7 9.9 20.1 15.6 17.8 20.7 16.8 10.2 12.7 9.8 8.7 9.0 11.0 7.5 8.4 12.9 7.2 17.6 14.1 16.2 17.1 12.5 10.4 12.2 15.9 15.7 16.2 10.6 14.9 13.0 10.5 17.1 12.0 14.2 7.7 12.3 11.3 29.7 5.9 9.2 12.4 16.7 12.2 10.3 13.4 15.4 14.9 20.3 8.0 12.7 9.7 12.1 4.4 7.4 18.9 8.8 4.6 7.4 4.3 6.0 3.1 9.4 8.7 9.9 8.7 5.4 4.1 9.6 8.5 10.0 8.6 7.5 10.1 7.8 5.9 3.6 23.8 7.2 13.0 8.2 7.8 13.1 5.9 11.0 8.5 17.6 7.2 8.0 9.1 9.7 9.2 17.1 12.0 10.3 19.8 9.8 16.1 7.1 15.6 5.5 8.7 22.1 8.5 13.2 10.4 14.5 8.0 6.7 15.8 17.4 8.9 8.0 6.7 5.6 5.6 5.0 6.8 10.9 7.8 14.3 6.8 12.5 8.8 18.9 8.8 8.5 4.3 5.2 7.4 4.4 5.3 5.0 7.4 2.2 3.9 5.5 3.7 4.6 4.7 3.8 5.2 4.3 15.7 20.1 20.7 16.8 14.1 16.2 15.9 15.7 17.1 15.4 RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792869-4885917 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "liver: 108.1;pancreas: 37.5" "Group enriched" "Detected in all" 4 "HDLM-2: 34.3;HEL: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm Nucleoplasm "HPA071308: " "prognostic favourable (5.48e-4)" "unprognostic (7.60e-3)" "unprognostic (7.55e-2)" "unprognostic (4.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.29e-1)" "prognostic favourable (8.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.59e-2)" "prognostic favourable (2.40e-7)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (3.66e-2)" 15.9 6.8 4.2 6.7 5.9 17.2 12.9 5.5 6.3 5.6 3.8 6.2 6.3 2.4 5.5 5.4 5.5 5.6 3.8 3.7 4.1 3.6 5.7 108.1 6.9 9.1 5.8 4.2 9.0 37.5 3.8 5.1 6.8 5.6 3.6 4.2 4.5 4.8 9.1 10.9 10.5 4.1 5.2 7.1 5.0 5.2 6.8 5.6 5.7 4.5 8.1 7.2 5.3 6.8 10.4 6.8 12.9 2.3 10.8 9.1 3.5 5.5 6.6 2.5 4.0 3.8 2.5 6.7 2.6 2.8 4.9 4.1 3.3 3.3 10.6 1.8 2.3 3.5 11.6 7.8 5.7 34.3 5.9 88.1 7.9 6.6 5.4 7.9 7.2 5.7 4.5 4.7 7.2 4.8 8.9 6.9 2.9 7.1 6.4 13.7 8.7 2.7 8.0 3.3 5.6 6.0 6.2 7.3 6.0 3.3 4.8 3.8 4.6 9.3 3.3 2.9 3.2 4.0 8.0 2.8 8.0 11.5 5.3 4.9 1.9 12.9 1.5 3.8 5.6 2.3 6.8 8.0 6.6 7.6 4.0 10.4 8.9 9.1 0.6 10.8 1.2 6.8 5.5 3.5 4.2 5.9 5.5 6.3 4.1 3.6 5.8 4.2 5.6 5.6 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621394-74666881 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA048258: , HPA075649: " "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 7.3 5.2 4.2 12.2 6.1 33.9 7.8 7.8 5.6 7.4 6.7 8.4 8.4 5.5 9.7 10.0 12.8 6.3 5.5 5.4 3.9 3.7 6.5 5.6 6.5 12.0 6.1 4.8 7.7 9.6 8.5 7.5 11.5 5.3 6.5 8.1 7.2 8.0 8.4 4.5 11.6 7.8 5.6 4.8 9.7 6.2 35.1 7.2 40.5 7.0 7.5 18.0 7.2 8.6 9.3 7.1 13.8 10.9 9.1 11.7 6.5 13.9 17.9 13.5 9.8 2.8 3.9 15.3 12.6 9.7 20.2 17.6 23.3 14.7 19.5 10.3 9.8 16.8 22.1 13.1 24.8 6.1 13.2 17.2 14.6 13.1 2.5 17.3 18.0 2.8 4.2 25.4 15.7 8.5 26.0 8.8 15.1 22.2 25.2 15.9 26.6 8.7 39.3 9.2 17.2 7.2 14.8 10.1 10.7 20.3 7.2 9.0 13.2 14.8 8.3 14.8 14.2 8.3 15.8 11.9 22.1 58.4 10.6 13.4 17.9 13.8 6.8 9.9 9.3 6.3 10.2 7.8 7.7 8.6 7.1 9.3 11.7 8.1 7.7 9.1 10.9 5.5 10.9 6.5 4.2 6.1 7.8 5.6 3.9 3.7 6.1 4.8 5.3 7.2 RING1 RNF1 ENSG00000204227 "Ring finger protein 1" Q06587 6 33208495-33212722 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008701 Supported Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA008701: AB_1079814" "unprognostic (2.12e-3)" "unprognostic (7.98e-2)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.91e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-1)" "unprognostic (4.75e-2)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.70e-2)" "unprognostic (1.62e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (2.13e-1)" "unprognostic (9.88e-2)" 26.7 22.6 17.8 15.9 21.3 12.0 14.6 27.6 24.2 22.2 17.6 22.0 21.0 18.2 31.9 17.3 14.5 18.8 21.4 14.4 17.3 18.2 19.3 21.6 16.8 14.5 24.0 15.4 25.0 18.3 24.0 34.0 14.9 17.0 21.8 7.6 20.0 19.0 20.5 18.0 21.7 19.5 22.9 18.5 23.2 24.1 16.9 20.8 25.5 29.3 13.1 14.3 13.9 17.1 1.2 2.2 0.8 1.5 0.2 2.2 0.2 4.2 3.5 4.2 4.0 4.2 1.4 9.7 11.1 6.8 4.5 4.6 3.8 3.1 6.9 4.6 4.4 7.6 3.6 3.3 3.2 8.5 2.9 8.3 5.8 7.1 9.6 4.7 6.8 0.0 3.4 4.0 7.5 1.6 11.9 5.3 4.7 0.0 0.3 3.7 1.9 4.6 4.5 6.9 7.6 5.0 3.7 8.3 5.2 4.0 4.3 11.5 4.9 8.3 2.3 5.0 3.8 0.0 9.1 6.0 6.2 6.6 3.7 4.3 3.1 0.0 1.5 0.8 2.2 0.4 0.4 1.1 0.7 1.0 0.7 1.2 1.7 0.9 0.3 0.2 0.5 2.2 0.4 0.2 17.8 21.3 27.6 24.2 17.3 18.2 24.0 15.4 17.0 20.8 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389496-7418037 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Approved "Nucleoli,Nuclear speckles,Cytosol" "Nucleoli, Nuclear speckles" Cytosol "HPA017866: , HPA051446: " "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavourable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 13.8 10.6 7.7 13.2 13.0 17.5 13.1 12.2 13.5 12.7 11.6 7.3 4.0 7.3 15.4 6.0 15.6 12.3 8.5 11.8 8.0 8.1 8.7 11.7 10.1 14.2 11.6 9.4 13.8 15.3 7.7 17.8 13.9 13.3 10.7 9.6 7.2 10.2 10.3 18.8 12.5 9.9 15.5 9.4 14.4 10.3 21.3 9.2 19.2 10.1 14.7 16.8 10.9 12.6 15.4 14.9 7.7 11.1 18.6 15.0 8.2 7.5 4.4 7.1 16.7 11.1 9.1 10.9 9.5 6.4 8.9 7.4 12.8 3.9 19.7 16.9 7.7 7.7 17.9 7.6 11.4 13.0 19.3 10.5 7.1 13.7 9.4 30.2 13.8 6.7 10.6 9.6 19.8 7.8 26.8 4.6 8.3 9.9 20.5 14.3 15.3 10.4 15.8 9.3 21.4 5.0 7.4 23.7 11.7 8.0 4.8 13.8 7.3 10.0 7.8 9.8 7.4 6.4 14.3 6.4 12.1 29.3 3.0 15.6 14.9 7.7 8.5 5.9 11.5 11.1 13.8 15.2 11.9 12.1 14.9 15.4 13.7 15.0 1.7 18.6 9.7 12.4 11.3 8.2 7.7 13.0 12.2 13.5 8.0 8.1 11.6 9.4 13.3 9.2 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 22.2 20.1 14.8 17.1 17.5 24.4 19.7 26.3 18.6 19.1 17.0 8.9 14.0 17.3 17.5 17.1 17.0 15.0 10.7 19.6 15.7 13.4 21.0 23.6 13.3 17.6 20.0 11.1 20.7 21.5 15.1 37.5 15.8 19.7 19.5 17.3 10.3 18.7 16.6 24.9 13.3 20.2 16.3 20.7 22.5 16.4 14.8 18.6 25.8 21.7 20.7 17.4 20.7 21.0 15.2 17.8 9.4 18.7 17.8 24.1 13.5 8.8 10.4 9.7 18.8 12.8 14.0 15.5 22.3 13.8 15.8 21.0 14.2 15.6 19.6 25.4 10.0 10.5 16.5 13.0 21.7 13.8 9.1 9.8 20.1 19.8 11.5 18.6 13.8 9.2 10.2 19.3 19.6 12.8 14.8 12.7 18.1 14.8 21.7 22.2 11.5 11.2 24.5 18.9 28.8 12.4 8.1 12.1 9.0 13.5 14.0 15.3 14.7 17.7 13.7 20.3 14.1 16.1 24.2 12.5 16.2 44.0 12.1 19.1 18.4 7.0 16.0 9.4 16.3 18.7 22.3 15.2 20.7 17.8 17.8 11.0 22.5 24.1 3.2 17.8 13.4 17.8 18.5 13.5 14.8 17.5 26.3 18.6 15.7 13.4 20.0 11.1 19.7 18.6 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23452823-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavourable (4.10e-4)" "prognostic unfavourable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 10.1 8.7 6.9 11.7 7.7 52.4 10.9 8.9 10.1 14.7 21.4 8.5 5.9 15.6 8.8 9.3 41.0 7.8 10.7 11.5 6.1 5.5 10.5 19.9 10.1 10.7 9.1 6.2 7.6 10.7 7.5 11.6 21.4 11.6 6.8 14.7 6.0 14.9 7.0 40.0 13.3 36.5 15.2 10.5 8.9 12.9 22.7 7.6 11.1 7.3 16.0 16.5 13.7 21.5 11.7 11.0 21.7 21.5 8.3 11.2 10.0 14.7 5.8 6.0 7.8 11.0 12.3 10.9 14.8 10.9 10.5 10.1 6.6 15.9 10.2 19.4 16.4 19.3 10.2 16.8 16.2 10.1 4.2 9.5 10.8 8.3 27.5 26.7 8.3 14.7 32.0 18.6 25.8 14.5 13.7 12.9 15.7 7.8 9.2 4.4 5.6 11.6 10.4 12.6 12.4 12.0 19.3 14.0 10.1 18.9 8.6 10.8 7.6 14.5 22.9 17.3 4.3 7.6 9.6 23.2 19.6 15.2 10.2 12.4 12.9 21.7 13.5 8.0 9.1 19.6 6.9 8.2 7.6 7.9 11.0 11.7 6.1 6.9 9.3 8.3 21.5 5.1 11.2 10.0 6.9 7.7 8.9 10.1 6.1 5.5 9.1 6.2 11.6 7.6 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063991-3115187 "Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Enhanced "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favourable (6.71e-4)" 24.5 12.0 6.9 15.7 12.4 10.5 28.0 11.9 11.0 16.4 18.9 9.6 22.9 14.5 16.8 17.7 17.1 13.5 17.9 12.3 7.5 6.8 18.5 36.7 16.7 19.8 11.8 6.6 13.2 19.9 14.4 17.9 24.4 10.2 17.8 16.6 10.9 21.1 18.7 11.4 18.9 24.8 21.3 6.9 19.4 15.8 9.0 9.4 18.6 18.5 15.2 19.2 15.0 20.4 4.1 3.2 6.6 3.9 6.6 7.6 2.1 9.5 6.9 10.4 10.7 22.2 14.2 5.7 15.1 20.5 16.0 18.4 9.3 6.6 9.0 14.6 21.6 11.0 12.9 12.4 17.5 18.6 7.0 11.5 4.5 6.7 12.5 10.0 14.8 19.2 11.1 14.8 10.7 13.8 13.0 5.2 15.4 12.4 6.9 10.9 6.5 8.6 8.4 7.7 10.1 14.3 19.2 9.0 8.8 9.9 6.3 16.7 11.4 7.1 16.7 17.5 9.4 6.6 11.1 8.0 10.3 9.6 7.3 5.5 19.4 1.1 3.0 6.4 6.1 3.7 4.9 2.0 4.9 7.6 3.2 4.1 4.1 5.4 6.6 6.6 3.9 2.9 5.7 2.1 6.9 12.4 11.9 11.0 7.5 6.8 11.8 6.6 10.2 9.4 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757747-89791063 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavourable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavourable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favourable (8.05e-4)" 12.0 5.5 9.3 11.2 7.9 13.6 10.0 3.0 9.3 9.7 7.9 10.6 5.2 3.5 10.9 7.8 8.3 7.0 17.3 11.6 9.2 8.6 7.7 10.4 18.7 10.9 11.8 5.8 8.9 13.2 14.7 7.3 20.8 9.1 10.7 5.6 4.6 10.2 5.8 3.1 10.4 6.9 10.4 16.5 14.2 8.3 5.6 11.5 5.1 8.5 4.9 11.8 15.0 7.6 7.5 6.9 19.4 11.2 3.8 5.5 4.3 10.1 3.5 1.8 2.6 4.4 6.1 3.3 11.3 19.3 6.0 7.8 3.1 5.3 7.9 17.6 6.3 2.4 4.8 3.7 11.1 5.6 4.9 6.6 1.7 3.1 12.4 2.4 3.2 4.9 3.0 8.5 27.7 6.3 3.2 2.6 5.5 2.1 0.0 5.0 1.0 8.4 1.7 2.5 3.8 14.0 4.6 0.3 2.0 2.7 7.1 5.3 6.8 3.0 5.6 3.7 3.5 6.2 5.2 5.2 2.3 4.7 9.0 0.2 2.4 8.8 5.7 19.4 3.6 10.6 4.1 7.5 5.5 4.7 6.9 4.3 5.2 5.5 4.5 3.8 11.2 2.3 1.2 4.3 9.3 7.9 3.0 7.4 9.2 8.6 11.8 5.8 9.1 11.5 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336021-24340045 "Enzymes, Predicted intracellular proteins" Necrosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.2;CAPAN-2: 8.1;HDLM-2: 4.6;SK-BR-3: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 7.6 1.3 1.8 9.7 2.4 4.3 6.0 0.9 1.6 4.5 13.6 1.8 1.4 10.6 3.7 3.8 9.2 3.2 12.7 2.6 2.7 0.6 3.8 1.3 6.4 7.2 3.9 0.8 1.7 8.4 0.5 0.9 3.7 2.3 3.7 11.8 3.6 7.5 1.7 2.1 5.9 25.8 2.1 3.8 15.1 9.2 1.6 3.6 7.2 8.7 6.1 13.3 4.6 5.6 3.5 5.2 6.3 8.8 3.9 9.1 4.3 0.0 0.0 0.0 0.0 3.1 3.4 0.0 0.7 4.2 0.0 0.0 0.1 8.1 0.1 2.1 0.3 2.0 0.0 0.1 0.0 4.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.1 13.3 0.0 2.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 2.6 5.1 6.3 6.3 7.7 6.4 3.5 5.4 6.2 5.2 3.5 2.9 4.0 2.6 3.9 8.8 2.6 9.1 4.3 1.8 2.4 0.9 1.6 2.7 0.6 3.9 0.8 2.3 3.6 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767106 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 16.3;HaCaT: 24.0;hTCEpi: 16.2;PC-3: 13.4;RPTEC TERT1: 14.5;RT4: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "naive CD4 T-cell: 1.5;neutrophil: 2.2" "Group enriched" "Detected in many" 17 "granulocytes: 2.2;T-cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030942 Enhanced "HPA030942: " "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (6.22e-5)" "prognostic unfavourable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favourable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.0 0.2 0.2 0.8 0.2 0.1 3.3 0.2 0.2 6.7 9.4 0.3 12.0 6.8 1.7 6.5 42.1 4.2 17.1 1.1 0.4 0.2 10.8 17.3 5.4 0.4 0.2 0.1 1.8 14.4 4.7 6.8 2.8 1.1 10.6 1.3 4.8 10.2 14.8 0.2 11.7 11.6 2.0 0.3 0.2 11.2 2.7 0.0 8.1 13.6 12.3 26.6 5.2 11.0 0.0 0.0 2.2 0.1 0.0 1.5 0.2 7.0 4.5 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.1 11.7 16.3 0.0 6.9 1.4 24.0 0.3 9.7 0.0 0.0 4.8 0.0 3.3 4.3 0.0 0.0 0.0 0.0 16.2 0.1 2.2 0.0 0.0 0.0 0.0 5.1 0.9 0.0 0.4 13.4 0.0 0.0 1.1 14.5 15.5 2.3 0.1 7.8 8.0 7.3 4.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.1 1.1 0.0 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603393-86623866 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved "HPA057922: " "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favourable (6.77e-5)" 13.2 13.5 18.0 9.8 20.6 9.8 18.5 38.3 24.6 15.8 28.1 16.9 9.6 15.6 18.8 39.7 11.7 12.7 23.3 29.5 16.7 15.9 13.1 43.8 8.6 8.5 17.8 10.6 13.2 20.2 23.8 12.2 16.2 14.7 20.5 14.2 14.5 13.8 16.1 17.7 10.4 27.2 17.9 21.8 8.1 18.7 13.7 16.5 11.9 9.0 8.8 8.3 13.4 11.5 1.4 1.6 9.9 0.9 3.0 3.4 0.9 5.6 7.7 3.9 6.0 18.0 11.7 6.4 8.1 12.5 4.2 5.7 4.4 9.7 9.4 9.9 12.2 6.9 5.2 6.4 6.4 7.8 7.1 5.3 3.5 9.8 17.1 1.7 8.0 16.9 13.5 6.2 7.8 12.6 1.9 5.7 11.5 6.9 4.0 4.7 1.8 5.5 2.5 16.9 5.5 15.4 8.9 6.2 6.4 9.6 21.5 8.0 8.2 4.4 14.2 8.2 3.9 8.2 4.8 19.9 6.6 6.3 6.5 3.0 3.9 6.5 0.7 9.9 1.1 0.9 1.5 1.4 1.6 2.4 1.6 1.4 1.9 1.3 1.5 3.0 0.6 1.0 3.4 0.9 18.0 20.6 38.3 24.6 16.7 15.9 17.8 10.6 14.7 16.5 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824077 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 7.2 5.2 6.8 4.8 6.8 6.4 7.7 16.2 7.0 6.3 3.4 4.6 5.7 3.5 8.9 5.0 5.8 4.3 4.8 23.5 5.8 5.6 5.1 3.9 5.6 4.7 6.2 4.7 4.5 5.8 5.9 3.5 5.2 6.5 3.8 7.3 3.6 5.6 27.6 3.8 3.1 10.9 4.5 4.2 3.8 3.4 4.5 6.0 5.0 5.4 4.5 4.1 6.3 2.7 2.4 9.0 2.2 3.2 3.2 1.4 11.1 4.6 5.7 4.2 10.4 13.7 4.6 8.4 15.7 6.2 7.6 5.0 4.1 7.8 9.6 12.0 7.8 6.3 5.8 6.8 7.8 4.1 6.2 5.9 4.6 6.6 9.7 14.5 7.9 5.1 6.3 7.6 8.0 6.1 12.8 11.3 8.4 7.1 6.2 7.2 9.8 6.8 5.7 6.5 12.2 3.8 5.7 7.9 6.8 8.5 6.2 9.3 9.3 9.8 9.1 7.1 5.4 8.9 10.8 10.2 8.3 4.6 6.6 5.7 9.0 2.2 3.2 3.2 1.5 2.7 2.7 2.2 3.2 1.8 2.4 2.3 3.1 1.7 3.2 1.6 2.4 2.0 1.4 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689499-49721529 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Approved Approved Cytosol Cytosol "HPA065983: , HPA071879: " "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favourable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 5.3 8.0 7.7 8.0 10.4 17.5 5.0 13.8 13.6 5.2 6.8 6.2 7.8 12.7 6.4 8.0 7.5 6.4 7.0 12.9 8.5 6.8 8.4 21.8 5.7 6.1 7.3 6.6 5.1 7.7 8.9 8.4 7.3 6.6 7.3 4.8 7.6 6.9 6.7 81.2 7.7 12.5 6.2 6.7 7.6 6.9 8.8 7.8 8.3 6.2 12.0 9.1 6.6 4.8 11.3 12.7 11.8 10.9 7.7 11.4 5.3 6.7 9.5 11.4 11.7 17.3 10.7 12.3 8.8 11.7 11.2 12.5 10.1 11.7 16.4 8.0 12.5 8.5 8.6 13.3 7.9 10.9 11.7 13.4 18.8 22.2 17.3 12.9 14.5 13.5 13.1 10.5 12.3 11.6 14.0 14.3 9.5 10.1 13.6 21.0 6.2 15.4 6.4 6.9 17.0 15.4 11.4 7.8 15.6 12.1 10.8 13.4 11.1 23.3 11.9 9.9 12.1 8.9 10.8 19.4 19.0 6.6 14.0 16.4 14.8 11.8 10.9 7.9 11.4 9.5 6.8 9.8 7.2 6.8 8.6 11.3 8.7 8.2 6.3 7.7 9.7 12.7 5.5 5.3 7.7 10.4 13.8 13.6 8.5 6.8 7.3 6.6 6.6 7.8 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018372-32073213 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "HMC-1: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavourable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 21.9 2.3 4.1 9.1 5.7 18.2 20.4 1.2 6.6 5.0 8.9 12.2 3.3 12.3 7.2 5.5 3.9 4.3 6.0 5.4 6.1 4.1 2.1 14.1 10.3 13.5 7.7 3.1 2.4 4.2 2.5 1.3 4.4 7.0 3.1 7.8 1.6 5.0 1.9 4.4 6.0 26.0 4.1 12.0 7.4 4.2 3.3 8.3 14.8 3.2 2.9 7.2 4.5 6.2 2.1 3.4 9.0 3.8 11.7 12.5 5.1 0.7 0.1 0.1 0.2 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 0.5 0.9 0.7 0.1 3.9 1.6 0.2 0.2 0.2 0.1 5.1 31.8 1.0 1.5 0.0 1.7 0.3 0.1 1.1 0.0 1.1 1.3 4.8 2.6 0.9 5.4 0.3 0.1 0.3 0.3 0.5 0.2 0.1 0.1 7.8 0.8 2.5 0.1 0.1 0.5 0.1 0.0 3.7 0.1 0.1 0.4 6.8 4.2 9.0 3.8 3.3 12.5 2.0 8.2 2.0 10.1 10.5 3.4 2.1 8.2 10.6 1.5 11.7 1.9 3.4 10.0 5.1 4.1 5.7 1.2 6.6 6.1 4.1 7.7 3.1 7.0 8.3 RNF126 FLJ20552 ENSG00000070423 "Ring finger protein 126" Q9BV68 19 647526-663277 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043050 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA043050: AB_10794768" "unprognostic (2.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-1)" "unprognostic (2.48e-3)" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (9.96e-3)" "unprognostic (7.04e-3)" "unprognostic (3.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 14.2 14.2 13.4 17.0 13.7 18.7 14.5 12.2 24.7 9.8 16.0 14.8 7.4 24.3 10.4 9.2 19.8 9.5 13.1 14.2 13.1 10.2 11.6 27.9 10.4 19.9 11.4 11.6 12.1 22.4 5.9 10.0 14.1 12.3 10.0 6.3 10.1 13.2 9.3 50.3 21.9 20.3 9.9 10.0 18.6 21.0 33.6 9.3 16.1 8.6 19.5 18.6 13.1 11.2 15.9 13.6 7.5 13.8 17.1 17.3 9.2 25.9 8.6 7.3 10.4 1.7 2.4 12.5 13.7 5.2 7.9 7.5 17.4 9.1 21.5 8.9 5.7 17.5 4.4 10.2 2.2 14.2 31.8 10.9 9.0 14.4 6.6 21.7 16.1 4.1 8.1 6.5 5.1 7.2 21.9 21.7 4.1 20.9 22.1 10.2 19.5 17.0 16.1 6.3 33.9 6.0 14.5 17.5 13.6 10.3 13.6 14.0 8.7 17.1 9.4 14.4 10.4 21.1 23.3 38.4 19.0 25.2 18.3 12.7 14.8 0.6 9.8 7.5 17.3 11.5 14.2 15.9 15.7 16.7 12.4 15.6 12.2 11.4 2.2 17.1 13.8 13.6 16.8 9.2 13.4 13.7 12.2 24.7 13.1 10.2 11.4 11.6 12.3 9.3 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128, E3 ubiquitin protein ligase" Q8TEB7 X 106693794-106796993 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.6;liver: 48.4;thyroid gland: 38.4" "Cell line enhanced" "Detected in some" "BEWO: 17.9;CAPAN-2: 14.8;Hep G2: 12.6;RPTEC TERT1: 13.0;RT4: 37.2;WM-115: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain "HPA019675: " "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 1.4 20.6 2.4 2.2 7.2 0.0 3.0 0.7 4.2 0.5 24.4 0.9 0.4 24.2 0.2 2.2 4.0 0.3 27.2 0.6 2.8 5.1 24.4 48.4 6.7 0.0 2.4 2.1 0.7 14.5 0.0 11.0 10.5 4.0 3.4 7.8 0.0 25.4 0.8 3.0 3.6 54.6 0.9 1.1 0.2 17.9 0.3 1.0 1.1 38.4 2.3 2.7 10.2 3.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 4.5 0.0 0.0 0.0 1.5 0.8 17.9 0.0 0.1 0.0 0.0 7.8 14.8 0.0 0.0 0.2 5.6 0.0 0.0 0.0 0.0 8.7 0.0 0.1 12.6 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 13.0 37.2 0.0 0.0 0.0 0.9 0.9 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 7.2 0.7 4.2 2.8 5.1 2.4 2.1 4.0 1.0 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812708-149962139 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 72.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles" Cytosol "HPA064784: " "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favourable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 24.0 21.3 30.6 19.0 39.4 9.8 28.5 19.9 30.4 19.0 17.7 39.9 16.2 14.3 16.8 33.7 16.8 15.9 20.4 16.4 40.5 29.7 35.8 39.2 31.7 19.6 60.9 26.8 18.1 19.6 23.5 14.9 32.4 40.7 25.5 20.3 19.5 36.1 20.9 18.0 18.4 16.3 20.4 102.2 25.5 17.0 12.5 51.2 13.3 32.1 18.8 15.9 21.4 16.5 8.8 15.7 72.4 31.5 7.8 8.5 14.6 19.4 12.1 8.2 9.3 32.3 19.8 13.7 10.8 27.8 10.4 15.5 10.6 28.0 8.1 15.8 13.2 18.5 11.0 13.8 14.7 9.9 8.0 9.7 5.6 10.3 21.5 10.4 13.9 20.9 26.3 8.8 23.9 11.5 3.0 16.5 9.3 10.9 7.5 6.9 5.5 9.5 5.4 8.8 34.3 20.2 9.1 4.3 12.5 8.9 13.4 34.7 25.5 11.1 12.0 14.2 5.7 15.0 6.9 28.0 18.4 16.7 11.9 9.8 7.6 12.9 20.3 16.6 6.8 25.2 8.5 8.8 7.6 7.6 15.7 8.3 7.3 7.5 72.4 7.8 31.5 11.2 8.3 14.6 30.6 39.4 19.9 29.2 40.5 29.7 60.9 26.8 40.7 51.2 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072118 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 17.0;classical monocyte: 38.1;eosinophil: 24.6;intermediate monocyte: 27.5;myeloid DC: 31.1;neutrophil: 68.1;non-classical monocyte: 23.8;plasmacytoid DC: 22.9" "Group enriched" "Detected in all" 11 "dendritic cells: 31.1;granulocytes: 68.1;monocytes: 38.1" "Low region specificity" "Detected in all" HPA014499 Approved "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favourable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 36.3 16.3 23.5 16.3 32.5 29.5 24.0 19.0 25.3 26.0 16.7 56.0 19.0 10.6 18.5 12.0 10.6 19.5 21.9 17.0 27.8 21.1 20.7 64.4 25.5 19.1 50.2 20.3 21.7 28.6 11.0 16.7 19.8 30.3 16.3 16.1 15.8 30.6 28.3 17.3 7.9 12.1 22.2 58.2 20.4 20.5 7.3 38.8 2.5 14.3 6.3 10.3 20.7 13.3 1.2 31.1 68.1 38.1 4.0 2.0 20.3 7.9 5.8 28.6 20.9 27.9 15.2 5.4 6.2 7.8 6.8 7.4 1.8 6.8 0.0 19.2 10.8 0.8 19.9 12.6 7.5 0.1 17.7 15.6 3.2 4.0 7.1 3.8 41.0 14.3 6.7 0.5 3.9 11.1 3.2 0.1 6.8 12.0 7.1 12.1 7.8 8.9 16.0 6.6 0.0 8.6 1.4 17.4 7.8 11.6 6.3 24.0 9.1 9.0 8.6 11.6 4.6 8.1 6.6 0.0 6.1 1.6 1.4 30.1 9.0 17.0 38.1 24.6 2.0 27.5 1.9 1.2 0.9 1.0 31.1 1.2 1.0 1.2 68.1 4.0 23.8 22.9 0.1 20.3 23.5 32.5 19.0 25.3 27.8 21.1 50.2 20.3 30.3 38.8 RNF133 ENSG00000188050 "Ring finger protein 133" Q8WVZ7 7 122697712-122699156 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 28.3" "Cell line enhanced" "Detected in some" "Karpas-707: 4.0;MCF7: 1.5;NTERA-2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.82e-1)" "unprognostic (2.52e-2)" "unprognostic (1.77e-1)" "unprognostic (3.04e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.87e-3)" "unprognostic (3.56e-2)" "unprognostic (3.72e-1)" "unprognostic (3.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.02e-2)" "unprognostic (7.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.39e-1)" "unprognostic (2.37e-2)" "unprognostic (7.61e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.2 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 4.0 0.0 1.5 0.0 0.0 1.2 1.1 0.0 0.0 0.8 0.0 0.4 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.1 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091855-32131561 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 43.8;bone marrow: 40.4;lymphoid tissue: 28.3;testis: 73.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 8.2 5.0 6.5 11.0 7.4 40.4 7.7 9.9 7.1 6.5 11.0 9.0 5.8 8.0 7.5 6.3 7.4 9.7 7.1 5.0 6.8 6.4 5.9 10.1 7.6 17.9 10.6 6.3 9.0 7.8 5.6 8.7 7.2 6.7 6.5 10.0 4.5 6.9 4.9 5.1 5.6 11.2 5.6 9.1 14.3 6.6 73.4 8.1 28.3 7.0 5.7 9.9 6.1 6.8 14.4 24.3 25.7 24.9 16.4 43.8 24.2 8.9 5.3 22.0 10.9 2.8 6.0 12.5 9.2 5.2 11.5 13.4 6.2 6.3 21.6 11.5 6.0 9.4 11.5 10.4 15.7 12.0 19.2 17.0 6.9 7.6 11.3 46.8 15.1 5.8 10.4 12.7 18.1 11.7 23.4 8.9 7.4 8.5 31.6 21.0 24.6 7.4 32.7 13.8 12.4 10.5 6.7 25.0 12.5 12.3 7.1 9.5 4.6 19.8 9.0 13.9 10.2 3.4 10.2 14.8 19.5 37.5 7.6 26.2 13.6 8.0 24.9 24.0 10.5 18.6 13.4 14.0 22.9 14.8 24.3 14.4 43.8 27.9 25.7 16.4 15.3 10.5 16.7 24.2 6.5 7.4 9.9 7.1 6.8 6.4 10.6 6.3 6.7 8.1 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474738-124487914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 15.1 17.3 10.4 9.5 12.2 54.5 13.4 12.0 17.1 14.2 10.9 14.0 9.4 6.2 15.3 10.0 12.2 14.2 11.0 11.4 10.4 10.8 11.4 17.7 11.3 14.2 12.4 11.5 17.1 10.3 7.6 10.6 18.4 9.9 12.8 10.4 10.2 10.3 10.5 15.2 12.6 11.3 14.2 12.2 11.8 11.2 60.3 13.3 16.8 11.2 9.6 10.4 14.8 10.7 9.2 9.4 11.8 11.7 8.6 13.9 8.0 13.2 8.9 10.7 10.5 23.6 18.8 8.8 11.9 22.6 10.0 12.9 5.7 11.1 13.7 14.0 15.4 9.8 9.1 14.5 15.0 18.9 11.4 20.3 5.8 11.7 18.0 9.6 11.8 16.0 21.2 10.6 28.7 13.3 14.3 21.0 11.8 35.8 16.2 6.9 7.5 12.6 6.5 7.9 13.7 18.8 17.0 4.5 11.7 15.5 38.9 16.8 18.7 10.4 10.5 6.7 15.5 11.3 13.2 17.1 18.1 12.4 10.5 16.3 6.7 3.3 7.4 11.8 11.6 4.7 13.9 9.2 10.8 13.2 9.4 8.5 10.8 11.3 10.8 8.6 11.7 5.1 13.2 8.0 10.4 12.2 12.0 17.1 10.4 10.8 12.4 11.5 9.9 13.3 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990291 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008716 Approved Supported Cytosol Cytosol "HPA008716: AB_1856337" "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favourable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavourable (2.21e-4)" "unprognostic (1.06e-2)" 21.2 29.5 23.7 11.2 33.9 7.8 22.0 22.5 40.2 18.4 18.7 26.2 16.0 15.3 21.0 21.5 15.6 14.3 15.4 32.9 23.6 24.7 31.3 31.3 13.8 13.3 28.9 17.3 15.9 17.1 26.3 28.8 23.6 47.7 21.6 19.8 20.9 18.1 20.1 27.7 11.9 20.9 20.5 26.3 13.8 15.7 33.7 15.0 16.2 26.3 13.3 14.9 16.7 14.0 12.3 17.1 32.6 18.8 16.8 17.0 12.2 12.5 21.0 14.8 29.0 26.6 27.9 9.9 25.8 14.4 18.2 20.2 17.4 14.7 22.2 30.3 26.5 6.9 18.8 25.4 16.3 16.7 16.2 14.1 11.0 7.9 29.3 15.5 12.6 20.9 22.4 24.1 30.4 22.5 17.1 31.1 37.2 15.0 15.0 4.9 6.2 24.0 9.9 16.4 24.1 25.0 21.8 16.3 13.3 22.6 41.5 43.9 28.9 12.1 23.2 24.2 7.8 11.4 24.4 19.6 22.8 20.4 20.7 19.0 29.8 32.6 13.4 13.0 17.0 15.8 16.5 12.3 15.0 16.9 16.2 10.6 11.5 16.7 3.3 16.8 18.8 17.1 16.7 12.2 23.7 33.9 22.5 40.2 23.6 24.7 28.9 17.3 47.7 15.0 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917392-7068286 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell line enhanced" "Detected in many" "HMC-1: 50.4;SH-SY5Y: 15.3;SK-MEL-30: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Approved Vesicles Vesicles "HPA049939: " "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavourable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favourable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 12.9 28.8 13.3 4.2 21.2 12.1 11.1 45.5 20.7 17.3 5.2 28.7 9.0 3.0 26.0 8.3 4.7 8.4 7.5 8.0 15.6 11.6 7.5 1.8 5.7 7.9 26.5 12.2 20.0 29.7 21.5 12.5 6.2 13.2 8.7 5.7 5.9 4.0 7.4 8.7 5.7 4.1 12.2 21.8 21.1 2.8 5.0 27.1 3.4 3.2 1.2 5.8 5.8 6.5 0.1 0.2 8.7 0.1 0.8 4.1 0.6 0.3 2.2 11.7 2.4 2.6 5.5 9.0 0.0 0.0 0.4 1.1 0.0 0.2 1.1 1.3 0.1 0.2 3.8 0.0 0.0 0.6 1.0 14.9 0.1 4.4 0.1 0.2 50.4 8.7 0.0 0.8 0.0 0.0 6.4 0.2 0.0 1.8 7.6 0.6 4.3 5.3 5.9 8.5 0.9 0.3 3.9 3.9 15.3 0.2 1.5 15.1 0.6 0.9 0.0 1.5 4.0 4.1 1.7 4.1 1.3 0.0 5.8 3.3 5.5 1.5 0.1 8.7 2.1 0.0 3.0 0.1 2.1 1.5 0.2 0.1 4.1 2.8 0.4 0.8 0.0 0.0 0.8 0.6 13.3 21.2 45.5 20.3 15.6 11.6 26.5 12.2 13.2 27.1 RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468874 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 54.7;hTCEpi: 17.4;HUVEC TERT2: 16.1;TIME: 16.1;U-698: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 28.8" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;granulocytes: 15.6;monocytes: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: , HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" 16.3 2.0 4.6 11.1 6.8 15.7 21.1 5.1 7.5 8.0 4.2 2.8 4.6 1.5 6.8 7.5 9.4 9.0 6.8 8.7 5.3 4.3 13.8 11.4 39.0 11.1 8.3 2.3 4.2 3.7 3.0 2.3 11.1 8.8 12.8 2.3 8.3 16.9 6.2 36.8 19.2 3.7 4.9 9.2 37.1 4.3 3.3 6.9 5.8 32.9 11.4 12.2 7.3 6.6 2.0 7.9 15.6 28.8 0.2 0.7 2.6 1.3 0.2 0.1 0.0 0.0 0.6 2.9 1.5 1.6 3.2 3.5 0.0 0.1 54.7 15.0 0.6 4.7 0.0 4.6 4.6 0.2 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.8 17.4 1.2 3.9 16.1 0.0 0.0 0.8 0.5 0.4 0.0 0.4 0.3 0.2 0.5 3.3 9.8 3.0 0.5 0.0 0.3 7.0 5.2 8.2 0.1 16.1 2.5 0.5 0.2 0.3 0.0 0.0 46.0 0.3 0.1 0.2 0.1 9.1 5.1 0.2 16.4 0.7 2.0 0.3 0.3 5.6 1.6 0.7 0.4 15.6 0.2 28.8 7.9 0.2 2.6 4.6 6.8 5.1 7.5 5.3 4.3 8.3 2.3 8.8 6.9 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266610-127288567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favourable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favourable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 27.3 20.9 28.5 16.6 29.1 5.1 23.9 63.7 34.5 22.7 18.6 29.2 10.5 11.8 32.0 35.2 14.2 17.9 21.3 25.2 26.3 21.7 20.9 16.8 21.0 17.3 30.0 27.7 28.5 12.6 26.5 27.4 27.8 31.3 18.6 17.6 17.5 16.7 20.3 55.9 16.0 15.2 26.1 28.7 24.6 15.5 16.3 27.7 9.2 26.7 15.5 17.6 19.2 18.7 11.7 14.2 22.8 22.8 11.5 10.3 9.1 5.5 7.0 26.7 23.5 24.7 24.8 9.7 18.9 30.2 10.1 14.5 9.1 8.4 10.0 13.4 15.4 7.1 7.9 8.8 14.8 11.5 6.9 12.7 8.4 12.7 24.5 7.5 9.0 21.6 18.7 11.4 22.8 17.7 13.6 9.8 22.2 10.6 7.3 13.6 9.7 7.3 9.4 6.9 5.0 14.4 6.1 16.0 16.1 7.3 10.4 11.6 7.1 26.0 20.8 17.8 5.9 18.4 13.3 14.2 8.8 6.6 13.6 13.2 16.8 16.8 18.9 16.1 9.3 20.0 9.7 11.1 8.0 10.3 14.2 11.7 7.3 10.2 22.8 11.5 22.8 7.1 8.6 9.1 28.5 29.1 63.7 34.5 26.3 21.7 30.0 27.7 31.3 27.7 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 123.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 123.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 123.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favourable (2.91e-4)" 20.3 13.4 7.9 29.0 10.9 32.9 13.5 7.9 10.8 12.5 16.6 10.8 11.4 12.3 11.3 12.8 28.9 14.3 14.5 12.1 9.5 9.4 15.1 19.6 24.5 47.4 13.7 6.2 14.3 21.1 14.3 10.6 19.4 11.2 11.1 12.0 12.8 15.8 8.1 8.8 20.2 16.8 9.6 13.9 65.0 13.8 15.2 9.7 17.0 12.7 13.1 24.4 14.9 17.2 2.1 9.3 123.7 21.3 2.3 9.0 9.9 9.6 5.7 4.3 5.5 16.3 16.4 25.5 12.0 15.8 16.2 18.3 14.4 25.6 2.8 14.5 11.8 19.7 6.1 12.2 15.1 8.4 8.4 6.0 5.1 24.3 21.8 6.4 9.7 15.0 20.1 19.2 12.7 29.5 5.2 9.0 16.2 8.2 8.6 6.5 3.0 10.4 5.6 7.2 11.1 19.1 23.7 5.7 4.2 7.2 17.9 17.3 4.8 8.7 19.5 8.2 4.7 12.2 2.6 18.3 10.7 0.1 2.6 9.0 6.0 5.8 13.0 14.8 8.2 20.4 7.4 2.1 7.3 8.1 4.8 1.5 5.1 5.3 123.7 2.3 21.3 9.3 9.0 9.9 7.9 10.9 7.9 10.8 9.5 9.4 13.7 6.2 11.2 9.7 RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808063-61894247 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 53.7" "Cell line enhanced" "Detected in many" "HaCaT: 16.0;SH-SY5Y: 9.9;TIME: 9.9;U-138 MG: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favourable (1.13e-8)" "prognostic unfavourable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" 8.3 3.9 2.4 2.3 6.8 1.5 8.8 19.1 3.8 8.5 7.4 4.0 6.2 2.2 8.6 10.4 4.5 3.9 8.0 6.5 2.5 3.1 53.7 28.3 7.8 1.2 4.1 1.4 3.8 3.1 4.7 2.6 6.6 7.7 4.7 6.7 3.4 11.8 6.8 4.6 9.6 9.8 4.6 4.2 1.3 5.7 3.9 4.5 0.0 5.1 4.9 2.0 5.0 11.6 0.5 0.4 1.7 0.4 0.6 0.4 0.2 0.0 0.0 3.5 0.8 3.3 0.4 0.0 2.2 7.0 0.5 0.4 0.0 0.1 0.1 0.7 3.5 16.0 4.3 8.5 0.9 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 0.5 5.9 2.7 1.7 6.4 0.0 0.0 1.0 0.6 0.6 0.0 0.2 0.0 0.2 2.3 0.0 0.3 2.6 2.9 9.9 0.0 6.3 1.1 3.8 0.0 9.9 16.2 1.7 0.0 0.3 0.0 0.0 0.0 0.5 0.0 5.3 1.7 0.3 0.4 0.2 0.3 0.3 0.3 0.3 0.3 0.2 0.5 0.4 0.4 1.5 0.6 0.4 0.4 0.3 0.2 2.4 6.8 19.1 3.8 2.5 3.1 4.1 1.4 7.7 4.5 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved "HPA049810: " "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favourable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favourable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 30.5 45.9 45.8 32.1 47.0 40.7 38.3 37.9 67.9 44.3 43.5 54.6 49.2 42.7 43.1 55.8 51.6 44.0 47.4 40.1 43.1 39.9 44.1 84.1 35.6 38.7 43.7 43.6 42.6 52.4 52.8 40.7 49.0 41.2 43.6 46.7 38.5 49.1 51.7 56.5 51.6 51.1 42.4 46.4 47.1 42.7 42.0 33.1 53.9 55.1 47.3 47.6 48.1 40.7 25.6 18.2 54.4 26.7 27.6 53.0 37.9 23.7 34.5 15.0 18.4 37.0 18.5 22.4 14.7 20.5 31.1 24.6 24.0 10.9 17.6 28.6 24.2 36.5 26.1 28.5 23.2 16.9 41.9 30.0 43.5 23.6 28.0 14.1 63.2 21.7 45.1 32.3 30.8 20.0 11.7 60.0 24.8 17.0 22.3 17.6 17.9 22.2 15.3 14.9 21.8 35.8 19.9 11.8 14.7 13.5 23.2 19.5 22.2 14.4 12.2 18.6 12.3 16.6 27.9 19.9 20.2 5.8 25.6 20.3 19.4 22.4 21.4 54.4 53.0 22.6 41.1 25.6 40.6 52.7 18.2 24.0 28.5 42.3 52.1 27.6 26.7 18.0 37.7 37.9 45.8 47.0 37.9 67.9 43.1 39.9 43.7 43.6 41.2 33.1 RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165844-64372869 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 54.0" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 24.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favourable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" 8.1 8.1 9.9 3.1 12.8 1.6 6.3 6.0 13.0 10.1 7.1 5.5 20.1 3.4 12.7 11.8 6.9 8.1 7.3 10.4 7.4 10.6 12.4 7.2 6.1 3.4 9.4 9.3 12.0 6.6 54.0 16.1 2.0 10.7 11.5 3.0 11.3 7.3 16.4 4.4 6.6 3.2 15.0 11.0 5.1 5.0 8.1 7.1 0.0 20.6 2.5 2.4 10.9 7.9 2.4 1.0 4.2 1.8 2.0 4.2 0.3 0.0 0.1 1.3 0.0 0.0 0.0 0.3 1.1 0.5 1.1 0.6 0.0 0.1 0.0 0.1 0.8 0.2 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.2 0.1 2.6 0.0 0.1 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.5 1.3 0.1 3.3 24.9 1.8 0.3 0.3 0.1 0.0 0.3 0.0 1.3 0.1 0.1 0.0 3.2 0.1 2.8 0.0 0.0 0.0 0.5 0.0 3.5 3.0 1.8 4.2 1.9 0.6 2.5 1.4 3.0 3.2 0.6 2.4 4.2 3.9 2.6 2.0 0.8 1.0 1.8 0.3 9.9 12.8 6.0 11.7 7.4 10.6 9.4 9.3 10.7 7.1 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980302 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.9;brain: 17.6" "Cell line enhanced" "Detected in many" "HeLa: 36.3;RPTEC TERT1: 29.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" Nucleoplasm "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.2 0.7 7.6 0.6 6.2 12.9 1.2 16.6 17.6 1.2 0.7 7.5 2.0 0.8 1.6 2.5 1.0 2.7 0.9 1.0 11.0 7.3 2.6 0.5 5.7 0.8 6.8 8.5 1.1 3.6 0.5 2.0 2.9 14.3 0.9 0.6 2.2 1.9 4.7 0.9 0.8 1.1 1.0 5.1 0.5 0.6 7.0 2.9 0.0 3.0 0.0 0.4 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 5.2 0.0 1.8 2.2 0.3 2.6 3.6 7.4 7.1 0.1 0.0 0.0 0.0 2.8 0.0 6.1 0.0 13.5 0.0 2.0 0.1 36.3 0.0 0.0 0.0 0.0 1.2 0.0 11.3 0.1 0.1 0.2 0.0 5.1 0.0 0.0 0.9 2.9 10.1 1.5 1.2 0.4 29.1 0.0 6.3 6.0 0.2 0.0 10.2 0.0 1.0 2.7 9.0 1.9 0.1 6.0 0.0 0.0 0.0 6.1 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 6.2 16.6 12.1 11.0 7.3 6.8 8.5 14.3 2.9 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160183-31207019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favourable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 18.3 16.1 15.2 11.6 20.3 6.8 18.4 16.7 23.4 19.4 17.0 24.3 14.4 15.6 21.8 20.2 20.5 18.3 13.6 15.6 14.7 15.6 27.6 39.7 14.4 11.1 15.9 14.6 21.2 23.5 32.5 24.3 19.8 20.9 30.5 17.3 24.1 27.0 23.5 18.0 22.9 24.4 22.8 16.4 14.4 18.0 11.8 15.1 12.6 39.9 14.4 18.0 19.4 18.5 10.3 12.6 21.5 15.1 15.4 14.0 13.0 9.4 5.6 10.9 12.3 22.1 14.9 10.4 11.3 21.9 15.6 21.2 6.2 4.5 9.0 6.4 20.0 6.0 10.4 11.7 16.1 8.9 11.2 3.9 5.4 7.6 31.0 9.5 6.1 15.8 42.1 10.9 25.4 13.0 4.6 10.8 18.6 6.7 8.1 5.4 4.8 6.2 8.5 10.9 10.5 11.2 8.2 4.8 9.8 8.2 11.0 16.6 7.6 6.3 9.0 11.1 8.0 12.8 5.5 15.2 12.3 11.5 14.5 6.0 8.8 15.0 14.6 8.0 12.4 15.1 14.0 10.3 12.7 13.8 12.6 9.0 12.9 11.8 21.5 15.4 12.2 4.7 13.6 13.0 15.2 20.3 16.7 23.4 14.7 15.6 15.9 14.6 20.9 15.1 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487061-228495766 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 15.7 30.3 25.6 12.5 28.1 12.3 10.3 33.2 54.7 11.4 10.7 15.5 12.5 14.7 12.9 12.2 18.0 14.2 14.5 17.7 25.2 24.9 16.2 20.4 11.5 9.8 20.2 29.3 20.2 19.4 22.3 16.4 8.8 22.7 15.0 6.6 12.3 30.3 12.6 55.5 15.5 13.2 8.6 16.3 19.0 14.2 9.5 11.4 11.1 27.9 19.4 11.2 10.0 13.1 2.0 1.7 8.7 2.1 1.0 2.3 0.6 9.3 7.0 4.9 10.3 5.4 3.5 9.5 7.8 4.8 4.9 3.7 3.6 6.5 21.2 16.3 8.9 7.4 6.2 6.6 1.8 9.6 8.0 6.4 5.2 4.6 14.7 7.3 12.6 6.1 11.8 3.8 5.1 4.3 10.2 41.5 3.5 5.2 11.6 6.5 11.0 7.2 9.9 4.5 20.0 3.5 5.9 10.9 11.0 7.9 16.5 21.0 11.6 17.5 9.9 6.1 6.3 6.6 7.4 75.5 22.6 11.6 16.4 7.7 10.2 0.0 1.1 8.7 1.3 2.1 1.5 1.2 1.5 2.3 1.4 2.0 1.4 1.2 0.3 1.0 1.4 1.7 1.3 0.6 25.6 28.1 33.2 47.3 25.2 24.9 20.2 29.3 22.7 11.4 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavourable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favourable (3.28e-5)" 28.2 13.8 30.2 21.8 20.8 34.9 26.7 16.3 29.5 40.6 22.8 26.4 11.4 17.0 29.4 19.0 17.6 24.7 30.8 20.1 28.7 16.1 23.0 33.9 28.4 35.2 19.7 25.2 24.8 20.3 14.5 15.7 18.6 23.6 20.7 19.2 11.5 19.8 14.2 23.0 26.6 38.5 32.7 30.1 22.7 21.5 35.4 27.7 25.1 17.0 14.7 29.5 33.9 23.7 13.5 11.4 17.6 10.5 4.8 14.4 4.5 8.4 5.4 4.8 5.5 9.1 7.9 6.2 7.6 7.3 7.2 6.6 2.9 5.6 5.0 14.0 7.8 6.0 3.7 5.6 9.9 21.1 3.1 8.4 25.2 4.2 7.6 1.6 5.4 7.8 8.6 5.8 10.9 11.1 4.6 58.8 7.1 4.2 7.6 2.7 1.7 5.1 3.1 3.3 9.8 19.8 13.3 3.8 8.2 7.9 4.8 7.3 4.2 6.5 11.0 8.4 6.7 6.2 4.6 28.6 18.3 3.4 5.5 5.6 5.0 17.6 7.5 6.5 14.4 5.6 9.0 13.5 11.8 10.8 4.6 12.7 6.1 8.8 16.6 4.8 10.5 11.4 12.0 4.5 30.2 20.8 16.3 29.5 28.7 16.1 19.7 25.2 23.6 27.7 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964685 "Enzymes, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.7" "Cell line enhanced" "Detected in all" "Daudi: 38.4;Karpas-707: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049587 Approved Approved Cytosol Cytosol "HPA049587: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favourable (3.39e-4)" "prognostic unfavourable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favourable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 8.6 11.3 8.0 13.1 10.5 36.4 12.0 14.1 14.1 9.9 13.2 10.1 4.8 14.1 10.8 6.9 23.3 7.9 10.1 8.5 6.0 7.2 12.0 6.5 13.8 12.9 9.6 9.3 7.1 7.0 6.4 5.7 9.4 10.2 7.4 15.3 9.0 10.8 5.7 10.2 13.6 15.5 10.6 8.0 9.0 7.4 54.7 8.3 6.8 8.2 11.1 16.7 11.3 12.8 1.3 1.3 16.1 2.0 0.8 1.6 0.7 6.6 5.1 4.4 4.0 2.7 3.8 29.3 3.0 3.8 5.6 6.0 5.9 19.9 38.4 5.3 4.0 9.5 5.4 7.3 5.1 14.1 3.5 3.3 4.0 5.9 8.6 5.0 7.0 3.1 13.7 12.2 15.1 11.7 4.1 46.2 5.4 2.1 3.3 6.3 7.0 5.8 4.5 6.3 3.9 4.3 9.6 7.0 3.5 9.8 3.4 21.9 2.8 7.4 12.7 3.0 4.2 7.7 5.3 11.1 5.6 13.6 4.4 5.2 4.5 5.3 2.0 3.5 1.6 1.8 1.2 1.2 1.4 0.8 1.3 1.3 0.4 0.6 16.1 0.8 1.5 0.6 1.5 0.7 8.0 10.5 14.1 14.1 6.0 7.2 9.6 9.3 10.2 8.3 RNF2 "BAP-1, BAP1, DING, HIPI3, RING1B, RING2" ENSG00000121481 "Ring finger protein 2" Q99496 1 185045364-185102608 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026803 Uncertain Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA026803: AB_10602086" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (1.35e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.08e-5)" "unprognostic (5.85e-2)" "unprognostic (3.56e-3)" "unprognostic (1.62e-2)" "unprognostic (2.01e-2)" "unprognostic (5.51e-2)" "prognostic unfavourable (1.94e-7)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (9.89e-3)" "unprognostic (2.52e-1)" 17.8 15.0 14.3 13.9 12.4 15.3 29.7 15.6 23.6 16.6 12.0 7.8 20.7 10.4 16.2 12.6 15.2 11.5 13.1 12.0 16.0 13.1 13.7 11.1 16.7 20.7 9.4 10.4 19.9 15.0 12.3 26.5 28.4 11.4 13.2 13.5 10.1 17.3 20.6 13.1 12.5 9.8 14.8 11.2 16.2 12.2 27.8 9.4 17.2 15.1 11.5 16.1 17.6 16.9 14.7 19.9 20.6 22.1 17.4 19.4 12.0 13.9 7.7 28.5 11.3 8.1 13.9 27.1 9.9 12.6 15.7 12.6 12.3 23.4 4.2 12.4 12.1 4.9 19.5 14.3 19.1 12.2 10.2 22.5 4.7 10.7 11.9 23.0 12.7 13.0 8.8 12.8 16.5 15.7 17.8 10.0 11.3 8.7 19.9 6.8 38.2 4.2 22.9 17.7 4.0 11.9 9.9 8.4 14.4 6.9 4.2 20.2 8.8 12.4 11.1 11.3 14.7 10.7 12.6 16.5 10.7 15.6 7.0 10.9 12.6 19.3 17.0 20.6 13.5 21.1 19.4 14.6 12.5 12.6 19.9 14.7 12.8 12.6 7.9 17.4 22.1 10.0 13.2 12.0 14.3 12.4 15.6 23.6 16.0 13.1 9.4 10.4 11.4 9.4 RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533851-101563344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA051773" Supported Enhanced Nucleoplasm Nucleoplasm "CAB012478: , HPA051773: " "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" 16.4 17.1 24.6 17.0 24.9 12.1 17.7 24.4 26.3 18.6 16.4 27.7 15.9 10.1 18.3 18.7 20.4 19.1 13.2 24.1 22.3 22.1 20.5 14.4 14.9 15.5 25.2 20.7 21.1 19.5 31.5 23.1 15.1 30.0 21.6 16.1 16.8 16.2 17.7 32.0 16.3 12.5 23.6 28.8 17.0 13.9 28.2 25.8 21.2 22.0 15.3 18.6 21.1 19.0 13.0 12.5 21.0 23.5 13.8 18.6 10.4 9.5 24.4 14.1 15.4 17.4 13.8 12.0 16.8 13.5 16.8 14.8 14.8 10.2 21.2 9.0 12.9 24.4 16.3 14.2 17.3 22.2 7.5 11.4 22.3 14.8 12.8 19.5 13.7 13.5 15.3 14.8 19.3 9.8 10.8 12.6 18.2 12.5 15.1 5.2 31.1 12.4 14.6 48.8 10.5 6.9 9.2 15.1 19.0 23.7 12.7 13.8 11.4 9.2 13.9 15.6 15.7 11.1 14.0 13.6 42.0 11.7 13.8 7.4 18.9 21.0 12.7 19.1 18.6 17.5 14.0 13.0 15.4 13.9 12.5 11.2 16.2 14.9 13.9 13.8 23.5 7.9 11.9 10.4 24.6 24.9 24.4 26.3 22.3 22.1 25.2 20.7 30.0 25.8 RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018955: AB_1858500, HPA021123: AB_1858501" "unprognostic (3.31e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.26e-4)" "unprognostic (2.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.40e-2)" "prognostic favourable (6.24e-5)" "unprognostic (2.88e-2)" "unprognostic (9.01e-2)" "unprognostic (3.49e-1)" "unprognostic (1.73e-2)" "unprognostic (1.06e-2)" "unprognostic (3.69e-3)" 16.9 14.9 22.0 18.8 24.8 22.2 18.4 33.5 27.8 17.8 26.9 22.0 13.4 11.5 26.9 13.3 18.7 19.6 14.2 29.1 20.5 17.4 12.7 11.8 14.9 23.8 23.8 14.8 25.6 21.3 23.2 24.9 14.6 20.4 17.7 11.8 18.9 16.2 21.5 22.5 15.1 20.1 25.0 18.7 23.3 18.3 34.3 26.3 18.5 19.8 9.6 24.1 17.7 30.7 8.8 6.7 24.5 8.4 10.0 9.7 6.5 14.4 15.6 12.8 21.8 15.3 13.3 8.8 15.5 16.3 16.1 14.9 11.3 8.3 12.7 8.0 17.3 10.4 13.3 10.9 13.2 7.9 11.6 9.8 9.5 11.4 18.4 16.0 16.8 13.7 14.0 12.3 15.1 12.7 19.6 8.9 17.8 22.2 6.0 25.5 17.6 13.0 15.3 18.1 7.1 9.6 12.2 9.8 15.6 9.8 24.6 8.8 9.7 16.4 13.8 16.3 29.4 16.6 13.9 7.2 5.4 10.3 12.2 14.9 25.9 1.3 7.7 24.5 9.0 8.4 9.0 7.3 7.9 6.7 6.7 8.8 9.7 9.1 13.1 10.0 7.7 5.4 7.0 6.5 22.0 24.8 33.5 27.8 20.5 17.4 23.8 14.8 20.4 26.3 RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962545-125092633 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 63.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 1.9;myeloid DC: 1.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavourable (1.92e-4)" 9.6 3.5 3.3 4.2 4.7 10.5 14.6 3.8 3.5 8.0 7.7 5.7 6.4 2.3 5.9 5.6 6.2 7.5 12.1 6.5 3.8 1.7 2.5 6.3 7.3 3.7 4.3 2.9 11.5 3.8 63.3 4.0 12.0 3.4 6.4 2.3 6.0 6.0 6.9 10.1 10.9 3.1 13.0 2.3 2.6 4.5 7.4 5.7 0.1 7.4 3.6 1.6 8.7 13.6 0.0 1.2 0.6 1.9 0.3 0.2 0.3 4.1 4.2 1.5 0.5 5.4 2.1 8.5 5.7 7.7 3.9 5.1 0.0 3.9 0.0 7.9 5.4 6.0 0.9 5.1 5.5 0.0 4.8 2.3 6.3 1.3 5.2 0.0 0.2 5.9 4.7 2.9 8.6 4.4 11.6 0.0 6.8 0.0 0.0 0.0 1.3 1.1 0.1 5.9 0.0 4.0 1.9 0.7 0.0 2.5 0.6 2.1 4.1 0.6 6.9 3.2 10.3 0.0 12.1 0.0 0.0 0.0 2.4 0.0 3.8 0.6 1.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.3 3.3 4.7 3.8 3.5 3.8 1.7 4.3 2.9 3.4 5.7 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663864-218672411 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA036420: , HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 13.4 12.7 13.9 11.1 16.1 6.2 13.7 13.4 27.6 17.3 13.3 17.1 9.8 4.3 16.6 16.2 12.2 16.8 11.8 17.2 13.1 16.5 13.7 15.6 11.9 12.1 12.1 11.6 17.8 13.0 19.3 14.8 17.7 15.4 14.7 9.0 15.3 13.6 17.9 16.9 15.7 10.3 16.0 10.0 12.9 11.8 18.4 9.1 15.3 16.8 12.7 16.8 14.0 11.8 13.3 8.2 23.3 11.2 14.8 15.0 13.9 5.9 7.6 6.9 8.0 10.5 6.4 7.4 6.7 17.0 23.2 21.7 12.6 4.0 3.9 5.4 14.2 5.4 7.9 13.2 10.1 4.3 10.9 5.4 5.6 11.9 12.9 4.7 5.9 14.2 12.4 21.1 14.2 12.7 9.0 6.2 14.9 16.9 5.3 5.8 10.9 8.7 7.5 4.3 5.8 14.2 6.3 7.0 7.9 5.2 5.8 10.0 6.9 8.8 7.3 13.2 6.3 5.1 9.6 5.3 4.2 6.6 11.1 5.9 8.0 23.3 10.6 14.9 13.9 10.3 12.6 11.9 13.7 13.6 8.2 13.3 15.0 11.7 8.9 14.8 11.2 7.4 11.5 13.9 13.9 16.1 13.4 27.6 13.1 16.5 12.1 11.6 15.4 9.1 RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160661 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol Cytosol "CAB009063: AB_2127706, HPA048745: " "unprognostic (3.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (9.05e-2)" "unprognostic (2.52e-1)" "unprognostic (6.24e-2)" "unprognostic (9.09e-3)" "unprognostic (1.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (6.21e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" 14.4 18.5 11.7 21.5 17.4 20.0 15.1 20.0 26.4 17.7 17.3 18.4 19.9 13.4 22.4 22.3 15.4 17.4 17.2 14.5 10.7 9.8 17.2 14.8 15.3 19.3 11.0 18.0 20.6 23.6 20.0 19.2 18.7 13.4 16.4 14.1 16.9 19.6 23.1 39.5 29.1 16.1 19.7 9.1 27.3 16.5 21.8 11.0 33.6 17.4 13.1 24.9 16.3 13.5 2.4 4.6 3.8 3.7 2.5 4.8 1.3 4.4 10.3 9.7 12.0 6.6 6.9 19.7 7.8 11.5 15.3 12.2 9.4 11.2 8.8 4.9 11.0 7.6 5.5 11.0 9.1 9.3 4.2 8.2 10.6 20.6 10.8 13.8 14.7 12.5 9.5 6.9 10.9 9.7 4.8 11.7 6.8 13.8 13.0 8.1 5.2 11.3 8.8 7.2 5.6 7.8 18.4 8.6 10.8 7.1 18.9 9.4 6.6 10.2 9.5 10.8 8.2 7.8 7.3 15.6 13.8 8.6 4.1 5.5 10.0 0.0 2.1 1.5 1.9 3.7 4.8 2.4 1.9 2.1 1.8 1.1 2.3 1.3 3.8 2.5 2.1 4.6 3.0 1.3 11.7 17.4 20.0 26.4 10.7 9.8 11.0 18.0 13.4 11.0 RNF40 "BRE1B, KIAA0661, RBP95, STARING" ENSG00000103549 "Ring finger protein 40" O75150 16 30761745-30776307 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041330, HPA054227" Approved Supported Nucleoplasm Nucleoplasm "HPA041330: AB_10793872, HPA054227: " "unprognostic (1.61e-1)" "unprognostic (1.74e-2)" "unprognostic (3.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.21e-1)" "unprognostic (4.01e-1)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "prognostic favourable (8.11e-8)" "unprognostic (9.96e-2)" "unprognostic (1.36e-1)" "unprognostic (6.55e-3)" "unprognostic (6.60e-3)" 21.0 25.2 26.4 21.3 26.5 40.8 20.9 36.8 28.2 25.8 21.0 22.0 18.0 20.1 28.4 17.0 25.6 24.4 21.3 22.8 22.2 17.1 20.0 21.2 20.2 21.9 20.9 18.9 30.5 24.4 44.0 21.6 25.3 19.6 21.4 15.1 20.0 27.3 21.1 20.0 25.5 20.3 18.3 18.6 20.0 19.6 43.1 22.8 23.5 26.8 15.4 20.6 22.5 21.4 7.6 12.0 15.0 14.9 9.9 13.3 12.9 20.3 31.9 19.4 18.4 14.8 15.5 21.2 20.8 16.1 24.1 18.8 25.7 19.0 16.2 30.6 17.8 22.1 35.3 18.5 18.9 23.2 41.4 15.8 35.0 26.7 19.8 27.4 18.6 14.4 15.5 30.2 17.1 20.2 34.8 15.5 14.6 34.0 26.1 25.7 20.2 19.3 51.9 21.4 31.2 10.6 18.1 32.4 23.8 16.3 20.9 15.0 32.0 31.2 21.8 27.1 13.8 19.1 23.7 23.1 28.5 32.2 22.5 24.4 27.6 6.2 11.5 14.7 12.9 13.4 13.3 7.6 7.2 9.9 12.0 6.5 5.4 8.3 15.0 9.9 14.9 6.2 6.2 12.9 26.4 26.5 36.8 28.2 22.2 17.1 20.9 18.9 19.6 22.8 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202175-56221933 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favourable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 22.2 17.6 18.6 11.8 30.2 12.0 14.3 30.9 47.1 16.2 15.0 16.9 12.3 8.5 16.4 9.7 16.5 17.7 18.0 22.6 17.3 22.4 14.1 10.5 16.5 14.8 15.3 18.2 17.0 16.0 17.9 16.7 14.6 25.3 25.2 13.6 14.6 10.5 15.6 21.2 10.1 10.8 20.3 11.8 13.5 12.2 10.1 12.1 11.3 20.5 10.1 17.0 16.2 11.5 24.6 13.1 41.1 11.5 13.4 12.5 12.3 7.5 11.6 12.6 20.0 26.5 19.3 9.4 25.3 25.1 22.8 18.5 14.2 9.9 14.6 13.5 21.4 8.7 17.0 12.2 16.6 15.2 9.3 19.6 8.3 8.1 55.6 21.4 21.4 24.6 28.7 19.0 33.6 22.1 13.8 15.0 12.6 12.2 12.2 9.6 15.2 13.6 13.3 9.1 8.8 12.1 11.1 23.1 14.0 22.1 12.7 20.0 17.8 25.2 13.3 11.5 12.3 14.8 9.7 10.8 12.4 13.3 13.7 12.9 13.7 21.0 11.5 41.1 12.5 11.4 11.2 22.7 10.6 10.9 13.1 24.6 11.0 11.2 15.8 13.4 11.2 10.2 12.1 12.3 18.6 30.2 30.9 47.1 17.3 22.4 15.3 18.2 25.3 12.1 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178354-32180793 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: " "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favourable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 9.8 20.6 19.3 9.0 20.6 10.3 14.0 13.6 16.8 11.3 25.7 17.4 14.7 18.1 12.3 14.6 15.9 16.9 13.9 19.2 16.9 12.0 32.7 38.1 14.7 11.6 16.3 14.2 19.0 19.3 7.2 5.8 23.4 12.3 13.1 19.1 12.2 25.3 15.3 24.5 13.4 36.7 13.7 19.7 10.2 14.2 9.6 9.6 10.8 18.0 14.2 12.5 13.2 9.9 6.7 26.9 7.2 6.4 7.5 7.0 6.5 5.2 6.8 4.6 17.8 5.1 3.5 3.6 2.1 2.7 4.6 5.3 9.1 4.4 6.8 7.7 5.1 4.3 8.6 4.8 4.9 4.2 11.7 5.4 7.7 18.7 6.0 0.0 11.1 3.5 6.5 7.8 5.9 9.3 13.9 7.4 6.7 7.4 6.6 15.6 0.0 2.9 4.5 5.3 9.5 13.1 3.3 4.8 10.0 4.1 4.5 4.6 9.3 19.1 4.2 5.2 5.0 0.0 8.1 4.0 6.1 8.0 3.6 12.1 3.0 5.1 4.6 7.2 7.0 6.4 6.1 6.7 5.7 6.2 6.6 6.0 6.4 6.3 2.4 7.5 4.5 26.9 5.7 6.5 19.3 20.6 13.6 16.8 16.9 12.0 16.3 14.2 12.3 9.6 RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353972-37394738 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA050731: , HPA064925: " "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavourable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavourable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavourable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" 8.0 11.7 13.1 8.2 17.8 8.9 11.5 25.7 18.7 9.2 9.5 10.6 6.8 6.9 13.5 5.7 18.3 12.0 8.8 17.6 13.4 14.8 11.8 7.5 10.8 8.3 12.0 16.0 13.2 6.5 11.9 16.4 10.2 13.7 8.6 8.2 8.0 10.2 11.9 15.2 9.9 8.4 10.7 9.6 7.7 7.6 19.8 13.8 6.6 8.0 9.4 13.3 12.9 15.2 8.8 8.3 2.6 8.1 7.6 10.8 5.5 6.5 3.9 9.5 11.3 7.7 11.1 2.7 6.8 8.4 12.9 14.2 5.8 3.7 8.1 4.2 6.6 6.2 13.2 8.6 13.6 8.5 12.8 14.0 6.9 8.7 4.4 7.4 10.3 5.5 8.3 7.7 9.0 12.4 9.4 2.8 7.4 4.3 9.0 9.2 6.6 5.2 7.1 8.8 5.6 6.6 4.6 18.8 6.3 5.1 5.8 9.4 5.2 7.3 5.6 8.5 7.6 8.0 10.0 8.4 11.1 40.0 4.2 10.6 9.8 1.0 4.6 2.6 10.8 6.0 10.0 8.8 8.1 10.2 8.3 6.0 7.1 9.4 0.6 7.6 8.1 3.6 9.3 5.5 13.1 17.8 25.7 18.7 13.4 14.8 12.0 16.0 13.7 13.8 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.6 8.6 13.5 17.1 7.9 8.4 8.1 12.9 8.5 10.5 13.3 9.8 4.3 14.6 10.6 9.2 7.1 15.7 10.4 19.4 19.8 12.3 19.0 7.8 7.8 6.5 20.3 10.8 5.3 9.2 10.9 10.6 9.3 18.7 11.8 15.6 7.5 8.9 14.5 8.1 7.6 17.7 20.9 8.3 9.4 8.8 7.9 11.4 10.7 6.5 7.0 7.0 20.4 7.3 8.5 7.9 9.6 17.4 10.7 18.7 8.2 12.5 15.2 15.5 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 RNMT RG7MT1 ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764558 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "HPA039409: AB_10795289" "unprognostic (3.02e-1)" "unprognostic (1.07e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (3.04e-1)" "unprognostic (6.17e-3)" "unprognostic (1.43e-1)" "unprognostic (3.76e-2)" "unprognostic (1.42e-3)" "unprognostic (9.45e-2)" "unprognostic (9.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-2)" "unprognostic (1.78e-1)" 18.9 10.1 13.3 12.7 20.4 40.1 16.6 19.7 27.3 14.0 11.5 10.3 12.1 9.1 15.4 13.1 12.6 12.2 9.9 21.2 14.9 18.2 12.9 12.0 12.4 14.6 14.5 21.8 19.6 13.3 16.6 21.2 16.1 28.5 14.7 11.6 10.8 12.8 12.2 29.1 14.3 11.3 15.1 16.1 12.3 11.4 17.1 12.6 12.2 19.2 15.8 15.8 26.5 11.4 20.1 20.8 21.6 13.1 9.4 15.7 4.1 11.4 6.8 13.2 9.9 9.8 12.5 9.2 9.4 11.7 9.8 13.3 8.0 5.5 12.8 11.6 9.6 4.6 15.5 13.5 16.6 7.1 8.3 9.6 7.0 7.5 10.8 25.0 8.2 9.5 14.7 10.3 29.1 7.5 14.4 12.9 11.1 7.1 15.9 9.0 10.1 5.3 10.4 13.9 17.4 9.0 9.0 10.2 15.3 10.6 7.8 18.1 6.8 10.5 7.7 19.7 27.7 16.0 10.0 26.0 28.3 26.6 14.5 9.6 9.8 21.6 13.1 8.5 12.5 10.3 10.1 16.2 11.9 10.3 8.1 20.1 15.7 12.2 7.1 9.4 11.4 20.8 12.8 4.1 13.3 20.4 19.7 27.3 14.9 18.2 14.5 21.8 28.5 12.6 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111851 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved 240000 "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: " "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavourable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 19.3 9.7 9.7 16.3 9.7 40.0 15.1 18.3 11.0 13.9 12.6 7.1 14.4 10.1 16.0 14.9 13.3 14.4 11.7 11.9 10.3 5.6 10.5 9.2 17.0 20.5 10.1 6.0 13.7 9.5 11.2 12.2 11.5 10.3 14.2 9.4 9.5 9.4 9.8 7.9 8.5 11.6 27.7 10.7 17.3 12.0 6.6 12.4 24.8 10.9 9.6 11.2 17.9 21.0 5.4 5.3 17.9 5.0 2.6 5.1 2.0 6.4 4.0 4.0 3.9 7.6 8.2 6.6 9.0 4.4 4.0 4.4 6.7 2.8 8.0 6.5 10.6 5.3 3.6 5.2 8.1 11.3 4.2 6.4 7.4 2.9 3.9 17.5 10.0 5.9 4.8 6.0 4.9 6.1 3.6 8.3 4.7 4.1 8.2 3.8 3.4 6.8 11.7 4.7 3.1 3.9 6.0 4.7 3.7 7.2 4.9 3.6 4.8 6.7 10.1 8.1 6.7 7.3 7.3 11.4 5.1 9.2 6.1 7.5 5.0 2.8 5.0 6.3 5.1 3.1 4.1 3.7 3.8 3.9 4.0 5.4 3.7 3.6 17.9 2.6 3.6 5.3 3.2 2.0 9.7 9.7 18.3 11.0 10.3 5.6 10.1 6.0 10.3 12.4 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179761-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol 3700000 Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavourable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 26.9 7.8 14.6 9.5 21.9 4.4 21.4 26.1 26.4 16.6 16.5 5.6 8.6 12.3 22.4 11.0 12.4 13.2 11.9 12.3 13.4 7.6 11.4 12.3 16.7 6.8 7.2 16.7 15.1 8.6 12.9 14.8 18.4 10.3 14.4 20.3 5.6 10.3 14.4 28.0 8.7 13.8 42.9 7.1 12.6 10.7 5.8 9.6 5.9 10.5 5.1 6.2 22.1 20.8 2.5 3.0 3.6 2.2 3.5 3.3 0.9 6.5 15.9 13.2 12.9 23.8 16.7 8.4 15.5 14.5 10.1 10.7 15.0 14.3 8.2 9.2 24.5 7.3 9.5 8.9 16.0 11.7 5.7 16.4 27.4 30.0 8.6 9.1 4.7 13.0 5.7 12.4 8.9 16.1 14.2 3.3 15.0 5.5 6.7 4.7 7.3 9.8 8.1 29.0 2.6 5.5 18.5 6.2 6.6 30.4 10.6 10.6 4.3 5.1 21.9 20.9 15.1 8.3 13.6 2.6 3.2 7.3 9.0 10.8 29.1 3.6 1.8 1.7 2.7 2.2 3.3 1.6 2.2 1.8 1.3 2.5 1.9 2.1 3.0 3.5 1.7 3.0 1.8 0.9 14.6 21.9 26.1 26.4 13.4 7.6 7.2 16.7 10.3 9.6 RORA "NR1F1, ROR1, ROR2, ROR3, RZRA" ENSG00000069667 "RAR related orphan receptor A" P35398 15 60488284-61229319 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 64.8" "Cell line enhanced" "Detected in many" "Karpas-707: 34.3;U-266/70: 19.7;U-266/84: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009861 Approved "CAB009861: AB_2180141" "unprognostic (1.57e-1)" "unprognostic (4.76e-2)" "unprognostic (2.22e-1)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (2.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (9.93e-2)" "unprognostic (1.34e-1)" "prognostic favourable (5.42e-6)" "unprognostic (6.94e-2)" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.62e-2)" 8.6 32.4 8.1 6.0 9.8 12.2 12.0 29.8 17.0 7.6 6.1 4.8 11.9 2.7 7.5 6.7 14.8 5.4 8.1 6.7 8.7 4.2 11.2 23.1 10.0 5.9 7.8 7.0 8.9 11.8 11.8 10.3 4.1 10.0 5.4 3.5 9.1 7.8 12.0 34.6 64.8 6.2 7.8 11.0 7.7 5.5 11.2 9.3 1.5 11.1 9.9 8.8 8.9 10.3 0.8 0.4 0.3 0.0 3.7 16.9 2.6 0.0 0.3 1.2 0.0 1.6 0.8 0.4 0.6 0.7 0.5 0.6 0.8 0.2 0.0 0.2 1.6 0.2 2.8 1.2 1.0 1.3 2.4 0.0 0.1 1.3 0.6 0.0 0.1 3.7 0.3 1.5 0.0 5.4 0.1 34.3 2.3 0.1 0.3 0.0 0.9 0.5 0.0 1.1 0.5 1.1 0.2 0.9 2.1 0.1 0.2 0.0 0.0 0.0 0.1 4.8 2.1 1.9 0.0 19.7 27.2 0.1 8.1 0.0 0.5 0.1 0.0 0.0 14.7 0.0 16.9 0.8 11.1 9.9 0.0 0.1 3.5 7.4 0.3 3.7 0.0 0.4 9.3 2.6 8.1 9.8 29.8 17.0 8.7 4.2 7.8 7.0 10.0 9.3 RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92298965-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA046443: " "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" 6.8 7.0 7.8 7.3 10.5 12.0 7.6 27.2 11.6 8.4 6.3 7.1 7.2 6.6 11.1 11.5 5.6 6.3 5.5 5.9 8.1 8.6 8.1 10.6 5.2 8.2 7.7 6.7 8.2 8.6 9.4 16.1 6.7 11.7 7.6 5.8 6.4 7.2 7.1 10.5 10.7 6.3 7.4 9.9 7.6 6.4 6.7 8.7 12.8 9.4 6.5 6.3 6.6 7.6 4.4 3.5 4.9 2.4 4.0 4.8 1.2 6.2 3.8 6.7 6.1 5.5 7.1 5.7 4.9 3.4 3.2 2.7 2.7 2.8 9.3 8.5 3.6 4.3 5.5 3.2 5.0 6.3 4.0 5.7 6.9 3.6 3.3 9.8 5.7 3.6 3.9 4.2 4.1 3.4 5.8 6.2 4.9 3.2 8.3 6.2 5.2 4.3 6.2 8.9 4.0 4.2 5.6 6.2 4.6 8.0 7.3 4.0 3.9 7.5 6.0 4.9 6.2 5.6 6.9 6.0 7.0 4.9 3.4 6.2 3.3 4.8 2.4 1.9 4.1 1.7 4.8 3.4 3.2 3.5 1.8 4.4 3.5 3.8 4.9 4.0 1.9 3.5 2.8 1.2 7.8 10.5 27.2 11.6 8.1 8.6 7.7 6.7 11.7 8.7 RPS6KA1 "HU-1, p90Rsk, RSK, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 45.2" "Cell line enhanced" "Detected in many" "HMC-1: 29.6;U-937: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 60.4" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favourable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favourable (1.84e-4)" "prognostic favourable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favourable (8.33e-4)" 11.0 8.2 6.3 24.2 9.7 15.8 5.0 14.4 6.3 4.9 23.2 11.1 4.4 24.5 2.1 3.6 8.9 6.0 8.0 3.4 5.3 5.1 13.6 5.4 26.1 32.7 10.3 3.5 2.1 10.1 10.0 7.4 3.3 8.6 8.6 15.8 3.6 19.0 5.5 1.1 9.0 45.2 2.8 7.9 27.0 9.7 2.7 9.0 15.9 13.9 4.9 17.3 6.2 4.5 5.0 22.0 40.1 18.0 7.9 8.3 17.1 9.7 3.4 2.8 3.7 0.1 0.0 3.7 0.8 1.5 4.2 4.0 4.0 8.1 18.3 4.5 0.5 11.5 6.3 22.7 3.0 15.1 4.1 20.1 8.5 7.0 1.3 23.7 29.6 0.7 8.3 3.8 6.9 1.8 3.4 6.7 0.2 5.4 0.8 23.3 7.2 11.0 12.6 3.6 8.0 12.0 2.7 4.1 1.6 6.9 6.6 3.2 4.2 20.3 1.2 0.2 5.3 0.7 3.3 4.1 4.9 10.0 2.5 31.8 4.0 9.6 18.0 40.1 8.3 16.4 6.9 4.9 6.1 7.3 22.0 5.0 3.9 5.5 34.5 7.9 17.3 8.6 6.0 17.1 6.3 9.7 14.4 6.3 5.3 5.1 10.3 3.5 8.6 9.0 RPS6KA2 "HU-2, RSK, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.2;ASC TERT1: 39.0;HHSteC: 39.5;HSkMC: 35.1;hTERT-HME1: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "eosinophil: 17.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: , HPA054237: " "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavourable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favourable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 15.4 6.5 26.8 5.3 35.5 6.9 12.7 12.1 21.5 13.5 7.1 20.3 11.5 4.3 18.3 5.2 14.0 11.9 12.5 40.9 25.0 18.3 9.9 3.3 24.6 10.6 22.4 18.4 20.9 30.2 32.6 18.0 12.1 22.7 10.6 7.4 11.1 9.0 10.5 14.4 7.5 7.2 15.8 37.2 16.5 10.4 5.1 25.7 0.8 24.8 3.5 4.9 15.5 10.2 0.4 3.9 17.5 1.6 3.3 0.6 0.2 2.1 0.0 4.3 6.2 53.2 39.0 0.0 4.6 8.9 2.5 3.6 0.0 1.3 0.2 1.5 16.1 1.9 2.2 9.9 2.3 0.9 0.5 0.0 9.4 0.1 39.5 0.1 1.7 35.1 7.1 13.7 42.4 13.9 0.0 0.0 10.4 0.4 0.2 0.4 1.1 2.5 0.7 2.2 6.2 2.7 2.3 2.4 16.8 1.6 4.3 5.8 0.1 3.3 5.1 9.1 0.9 25.1 1.3 1.2 1.8 0.6 6.0 0.2 8.6 0.1 0.5 17.5 0.5 0.7 0.2 0.3 0.5 0.2 0.7 0.4 0.6 0.3 0.4 3.3 1.6 3.9 0.4 0.2 26.8 35.5 12.1 21.5 25.0 18.3 22.4 18.4 22.7 25.7 RPS6KA3 "CLS, HU-3, MRX19, RSK, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 19.7 12.5 9.9 23.0 12.5 8.2 16.5 15.2 12.1 11.4 23.2 4.4 22.1 13.7 12.4 10.1 13.6 12.7 15.7 21.3 9.7 8.8 14.1 25.8 21.6 34.0 9.9 10.0 12.7 14.0 36.6 9.8 11.0 10.2 14.5 18.8 7.7 14.3 11.3 45.2 11.7 23.7 16.1 11.7 25.8 11.8 4.8 9.7 29.4 13.5 15.0 18.2 20.3 19.0 4.2 8.6 12.5 6.9 8.3 11.3 2.7 12.6 22.2 8.4 4.3 8.2 14.5 2.5 11.0 16.8 8.2 11.3 25.1 16.4 8.3 3.8 11.5 9.0 9.6 9.3 15.3 7.0 7.6 9.8 14.0 67.5 8.4 19.0 10.2 9.2 7.5 12.9 16.3 29.8 6.4 23.9 8.6 6.0 12.3 5.8 6.0 13.4 6.6 17.8 9.6 7.1 10.6 3.9 3.8 14.8 4.5 16.0 0.0 5.7 16.6 9.0 6.3 28.5 6.2 19.1 11.6 9.3 17.0 9.5 21.2 12.5 4.7 9.5 6.3 6.9 11.3 2.9 7.3 6.9 7.0 4.2 5.0 6.0 7.5 8.3 6.9 8.6 3.5 2.7 9.9 12.5 15.2 12.1 9.7 8.8 9.9 10.0 10.2 9.7 RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.6" "Lineage enriched" "Detected in many" 4 "dendritic cells: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB008649: AB_1619460, HPA023225: AB_1854144" "unprognostic (2.30e-1)" "unprognostic (7.05e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.47e-2)" "prognostic unfavourable (8.17e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (2.45e-1)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-3)" "unprognostic (1.98e-2)" "unprognostic (3.93e-3)" "unprognostic (5.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" 14.9 9.1 13.3 15.7 17.1 13.2 7.6 37.6 22.7 7.7 12.4 13.1 5.8 14.0 11.0 6.9 18.5 8.1 10.5 7.8 10.9 10.1 8.7 9.6 10.9 15.0 16.7 9.9 6.5 9.2 5.7 4.7 16.6 9.8 8.3 8.4 10.0 10.9 8.9 16.3 17.3 15.4 9.8 11.5 22.2 18.3 3.3 13.5 7.6 6.7 16.7 16.4 9.7 8.8 0.5 12.6 1.4 3.0 0.3 1.0 2.1 27.7 15.5 2.2 5.7 5.0 4.7 32.1 14.7 7.8 11.6 5.8 15.4 14.6 2.8 17.3 8.5 25.7 2.7 12.0 5.7 8.7 5.2 6.5 13.3 7.8 5.0 6.6 12.2 4.7 11.3 9.8 8.1 7.0 2.6 4.0 5.9 25.4 5.9 10.3 2.5 32.9 11.7 9.3 9.3 8.0 12.9 3.3 2.6 15.3 9.4 12.9 11.0 8.2 13.9 15.8 19.9 28.6 13.2 4.8 3.7 2.9 10.5 7.6 8.0 1.1 3.0 1.4 0.9 2.4 1.0 0.5 0.7 0.7 2.7 0.4 0.4 0.4 0.2 0.3 1.4 12.6 0.6 2.1 13.3 17.1 37.6 22.7 10.9 10.1 16.7 9.9 9.8 13.5 RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847862-91060636 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Enhanced Nucleoplasm Nucleoplasm "CAB025458: , HPA001274: AB_1079417, HPA001780: " "unprognostic (3.05e-2)" "unprognostic (2.19e-3)" "unprognostic (4.27e-4)" "unprognostic (1.98e-3)" "unprognostic (4.79e-2)" "unprognostic (4.20e-4)" "unprognostic (3.70e-2)" "unprognostic (5.80e-4)" "unprognostic (6.70e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-4)" "unprognostic (5.73e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" 4.9 2.4 8.3 13.0 21.6 5.8 16.3 32.9 12.2 7.0 11.0 12.0 4.2 9.3 11.8 2.6 11.9 8.9 6.7 6.1 9.0 7.9 4.5 4.1 6.1 7.3 12.8 9.7 10.2 4.9 12.0 6.9 14.9 11.0 8.0 11.7 2.8 8.7 9.9 14.3 6.6 9.8 19.4 17.1 7.4 9.8 5.2 13.7 4.8 8.6 7.8 7.7 11.6 7.3 5.8 2.5 20.0 3.2 8.4 7.1 2.2 1.2 1.7 2.0 1.3 0.0 0.4 8.5 0.7 1.1 2.2 3.4 0.9 2.2 5.8 2.4 2.1 3.7 1.7 1.7 4.7 0.9 3.1 5.8 1.6 0.2 0.0 5.7 29.5 0.5 3.5 1.4 1.1 2.4 0.6 6.6 2.3 2.4 1.7 2.9 0.6 2.6 3.1 9.4 2.9 2.5 2.2 9.9 3.1 2.4 14.8 8.4 2.8 1.9 0.5 0.7 1.3 0.6 2.9 2.9 2.7 5.0 1.4 4.2 9.3 10.5 2.7 7.8 3.6 2.1 5.9 4.4 4.8 3.5 2.5 5.8 5.6 3.0 20.0 8.4 3.2 1.0 7.1 2.2 8.3 21.6 32.9 12.2 9.0 7.9 12.8 9.7 11.0 13.7 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84187907 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 20.7" "Cell line enhanced" "Detected in many" "NTERA-2: 10.8;PC-3: 11.7;RH-30: 14.4;SH-SY5Y: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.7 2.9 5.9 1.0 12.2 0.0 2.3 4.7 5.1 3.1 4.5 1.1 20.7 1.7 2.7 4.0 1.5 4.0 1.9 1.2 5.1 2.9 9.2 0.9 0.8 0.2 1.5 3.3 4.9 3.4 13.5 9.1 0.5 4.4 4.3 3.7 1.5 3.0 15.0 1.4 2.3 2.0 1.7 1.0 0.6 2.4 2.6 2.7 0.8 14.5 0.9 0.6 3.3 2.3 1.2 0.8 2.4 0.5 0.7 2.8 0.1 0.0 3.6 3.5 0.0 3.4 3.4 0.0 7.5 4.0 3.4 2.8 2.7 3.0 0.0 0.0 4.1 0.1 9.0 6.0 7.9 0.0 4.5 0.0 0.1 0.0 3.0 0.0 0.0 1.9 0.0 0.0 3.7 0.8 0.0 0.1 2.7 0.0 1.3 0.1 10.8 11.7 0.0 14.4 0.0 0.5 8.3 0.0 11.5 0.0 4.2 0.0 1.9 0.0 0.0 0.1 4.3 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 2.4 0.4 0.5 0.5 0.3 0.4 1.2 0.4 0.7 0.8 0.6 0.4 0.4 1.1 0.7 0.5 0.4 2.8 0.1 5.9 12.2 4.7 5.1 5.1 2.9 1.5 3.3 4.4 2.7 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: " "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.6 10.4 8.9 8.4 6.1 9.0 6.7 9.9 9.2 8.7 9.7 8.5 5.3 12.9 12.3 8.2 5.5 11.7 8.9 14.0 7.1 13.1 8.8 6.8 9.7 9.1 13.6 8.9 9.1 6.8 10.1 7.5 11.3 11.7 8.3 6.4 74.4 16.1 5.8 6.0 8.0 9.5 15.0 12.1 7.2 7.9 6.5 7.8 8.3 4.8 5.2 9.5 7.5 9.7 8.5 14.1 6.9 13.1 15.0 12.7 14.5 6.4 8.4 6.7 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 RPS6KB2 "KLS, P70-BETA, p70S6Kb, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435408 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavourable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 8.7 14.1 8.5 12.8 9.2 18.0 11.2 12.9 11.5 13.1 13.0 12.5 12.3 19.8 10.2 10.1 36.1 11.0 10.7 10.7 8.8 4.2 11.3 27.8 10.7 12.0 11.4 8.7 9.5 18.7 9.6 11.7 13.8 8.7 17.2 9.9 11.7 18.1 15.8 25.0 41.4 17.7 8.8 7.6 18.6 17.1 7.5 8.8 21.8 11.4 28.6 21.8 10.1 15.6 15.7 27.1 16.4 28.3 17.8 20.7 20.2 21.7 16.5 9.0 15.2 4.2 8.1 11.8 10.5 13.2 19.7 13.7 25.7 14.6 8.0 18.3 10.3 16.2 10.1 16.0 8.0 13.8 27.0 12.9 21.0 20.9 14.2 16.3 16.0 10.3 16.9 10.4 10.7 14.6 20.7 21.5 9.9 33.3 25.1 25.7 9.7 21.2 18.6 12.5 38.0 9.1 12.5 13.6 14.6 10.8 30.1 22.4 35.4 13.6 6.1 10.3 11.0 24.8 11.7 19.3 15.8 12.9 16.9 10.3 12.8 9.7 22.6 16.4 15.7 25.2 15.9 15.7 14.9 15.3 27.1 14.3 10.9 11.9 15.1 17.8 28.3 18.7 20.7 20.2 8.5 9.2 12.9 11.5 8.8 4.2 11.4 8.7 8.7 8.8 RPS6KC1 humS6PKh1 ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274773 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Enhanced Endosomes,Lysosomes "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: " "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 12.0 14.1 15.6 10.0 19.4 6.4 17.1 13.5 19.4 14.1 13.1 12.6 8.8 9.2 15.9 8.4 10.3 11.8 11.6 9.4 17.3 15.6 9.8 10.8 13.6 7.5 17.8 16.8 14.4 13.5 19.9 16.7 12.3 15.3 17.6 10.1 7.3 8.9 17.7 14.1 6.7 8.7 18.5 22.3 11.0 12.5 26.5 13.2 6.8 10.4 6.1 7.8 14.6 16.0 2.5 8.7 13.7 6.8 4.0 3.3 2.2 7.4 6.4 10.6 11.4 10.6 15.7 9.3 9.8 14.4 15.2 17.5 5.2 8.3 4.7 6.6 14.7 6.1 12.8 8.0 11.6 9.9 4.7 12.7 7.6 7.2 9.8 8.0 15.1 10.3 6.9 13.3 7.3 12.6 16.3 7.3 15.5 4.0 3.3 2.6 15.3 7.3 4.0 10.0 4.6 7.0 7.5 6.2 16.1 10.6 8.4 14.0 12.0 3.4 11.7 10.4 9.6 11.9 6.4 4.3 8.3 3.6 4.4 3.1 10.6 13.7 4.6 3.3 2.8 6.8 2.3 2.5 2.3 2.4 8.7 1.9 1.5 3.3 0.5 4.0 6.3 1.0 1.6 2.2 15.6 19.4 13.5 19.0 17.3 15.6 17.8 16.8 15.3 13.2 RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266207-100292769 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm 8700 Nucleoplasm "HPA027982: AB_10601769, HPA027990: AB_2672452, HPA028151: AB_10602099, HPA028331: " "unprognostic (4.79e-2)" "unprognostic (1.17e-2)" "unprognostic (3.97e-2)" "unprognostic (3.82e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "prognostic unfavourable (2.76e-5)" "unprognostic (9.55e-3)" "unprognostic (3.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.46e-1)" "unprognostic (8.09e-3)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.94e-2)" 20.9 25.0 19.4 17.8 24.9 25.5 20.0 22.6 31.7 14.7 22.9 20.3 19.9 31.7 14.2 26.0 27.0 13.4 19.9 25.5 20.0 21.0 31.7 23.0 16.1 21.8 21.5 20.7 13.3 27.7 21.1 17.2 21.2 33.1 20.9 22.2 14.1 18.5 17.4 35.4 14.6 37.8 15.4 20.5 24.2 21.8 12.2 12.4 25.0 18.3 20.2 20.8 18.7 17.5 9.6 8.0 8.2 19.6 11.0 20.1 7.7 21.5 11.2 11.0 14.8 14.0 22.8 30.2 25.6 12.5 16.7 14.4 18.2 10.9 22.1 19.5 16.2 11.0 13.5 12.1 20.2 22.1 11.3 14.6 12.8 22.9 21.6 26.5 23.1 18.5 19.1 21.9 29.2 20.7 25.0 33.7 25.2 7.1 13.6 20.6 16.9 21.7 9.8 19.8 9.7 20.5 17.7 8.9 11.1 16.5 24.0 35.0 5.2 34.0 18.0 15.8 11.1 24.7 30.7 19.6 19.6 17.7 33.3 23.0 9.4 8.2 9.1 7.5 10.8 11.3 13.8 9.6 10.0 12.8 8.0 7.1 9.3 10.5 4.4 11.0 19.6 7.6 20.1 7.7 19.4 24.9 22.6 31.7 20.0 21.0 21.5 20.7 33.1 12.4 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.9;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 14.9;monocytes: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favourable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavourable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 18.5 10.1 9.9 10.4 6.7 19.6 36.8 4.6 9.8 11.0 9.3 4.9 8.1 14.0 10.1 6.1 24.2 9.3 12.9 14.2 9.0 3.7 11.7 49.3 12.8 10.4 6.0 7.0 11.7 20.6 8.0 10.7 9.6 9.4 9.7 2.0 9.5 9.3 9.7 45.8 19.0 15.2 10.6 9.5 11.5 8.8 5.9 8.1 1.5 13.6 18.3 5.9 16.0 23.7 0.1 1.7 14.9 12.3 1.3 1.1 1.8 5.5 15.6 2.0 5.0 3.5 3.3 24.0 3.0 3.5 4.3 2.5 8.6 8.7 0.0 8.2 4.3 27.0 0.7 10.6 0.2 7.9 2.0 0.0 19.0 13.1 4.5 6.5 2.4 5.3 4.5 5.4 2.5 3.7 10.7 0.5 1.0 14.9 0.5 1.4 3.8 5.4 2.8 7.4 10.8 0.2 24.1 4.4 2.0 9.5 9.1 2.4 12.6 8.9 4.8 5.3 6.4 5.7 2.6 0.7 0.0 0.1 4.0 6.6 3.4 1.1 5.2 2.8 1.1 9.3 0.0 0.1 0.7 0.7 1.7 0.0 0.2 0.9 14.9 1.3 12.3 0.1 0.9 1.8 9.9 6.7 4.6 9.8 9.0 3.7 6.0 7.0 9.4 8.1 SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavourable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavourable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.27e-1)" 20.1 17.8 26.7 22.8 30.5 24.0 18.6 21.9 45.9 23.6 50.1 17.6 21.6 14.0 30.2 13.1 27.5 21.3 17.1 22.5 21.2 23.9 14.6 16.0 19.2 30.6 20.4 34.6 19.0 14.4 28.0 13.9 26.8 24.3 20.2 27.3 20.9 15.7 28.6 24.1 19.0 20.1 38.5 15.9 25.8 30.5 60.2 16.2 32.7 37.5 17.2 37.5 33.0 25.8 19.1 22.3 22.8 19.0 35.2 41.3 29.4 35.5 39.0 61.3 29.2 21.0 24.8 20.8 44.0 38.4 49.7 60.8 33.6 23.7 42.9 17.4 35.3 17.0 62.8 27.7 54.2 35.8 45.6 41.6 26.3 38.2 23.2 46.1 26.0 18.5 14.3 27.1 29.4 47.6 49.5 21.7 46.9 28.6 30.2 127.3 30.6 20.9 47.6 41.1 17.6 22.3 42.1 24.2 26.7 45.1 31.1 26.6 25.4 28.2 24.7 26.1 30.1 17.2 47.3 27.1 78.7 60.9 18.4 38.4 38.2 22.8 19.0 10.4 23.0 16.9 24.8 19.1 29.0 23.2 22.3 15.7 41.3 31.3 7.9 35.2 11.3 15.0 33.5 29.4 26.7 30.5 21.9 45.9 21.2 23.9 20.4 34.6 24.3 16.2 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavourable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.3 8.7 8.9 10.4 11.3 18.0 7.8 12.2 14.1 9.7 9.3 13.8 6.6 8.2 11.7 9.5 9.9 9.4 8.2 8.0 9.6 8.5 6.8 7.8 7.9 9.1 9.7 9.0 11.6 8.4 16.3 13.8 10.4 9.6 9.1 9.8 8.8 11.3 8.5 10.5 11.6 8.9 10.3 8.9 8.3 9.0 50.3 9.9 17.1 8.8 6.9 11.9 9.9 9.5 5.8 6.8 15.6 8.5 3.5 6.2 3.5 20.3 11.3 21.2 17.1 14.1 9.8 23.3 13.0 12.8 20.2 16.0 26.7 8.5 17.0 11.8 14.7 14.3 23.4 13.4 21.1 9.4 15.0 16.9 10.1 20.7 17.0 14.6 13.4 9.1 10.1 26.7 16.8 16.1 20.4 12.7 16.8 22.7 20.3 11.5 21.9 12.6 14.0 17.5 11.4 10.8 18.1 11.2 13.5 13.7 13.0 8.1 9.8 10.1 13.7 19.6 21.3 18.1 13.7 17.8 17.5 20.4 16.1 9.9 12.5 2.4 4.2 4.8 6.2 3.0 4.8 2.4 4.4 4.0 3.7 5.8 3.2 3.5 15.6 3.5 8.5 6.8 3.0 3.5 8.9 11.3 12.2 14.1 9.6 8.5 9.7 9.0 9.6 9.9 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28292519-28323849 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 31.1;lymphoid tissue: 22.1;skeletal muscle: 39.6" "Cell line enhanced" "Detected in some" "AF22: 15.0;AN3-CA: 10.8;NTERA-2: 15.4;REH: 16.3;SCLC-21H: 23.8;SH-SY5Y: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.3;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.4;naive CD8 T-cell: 3.0;NK-cell: 1.4;T-reg: 1.4" "Group enriched" "Detected in many" 10 "NK-cells: 1.4;T-cells: 4.3" "Region enriched" "Detected in all" 5 "cerebellum: 306.7" "unprognostic (5.15e-2)" "prognostic favourable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.9 2.0 8.0 1.8 7.3 2.0 1.7 31.1 17.5 1.7 1.2 1.5 0.0 1.1 1.9 1.3 1.5 1.6 1.0 1.8 9.9 5.6 1.6 0.9 1.8 2.7 6.0 4.0 1.1 2.7 4.2 4.1 0.8 8.3 2.6 1.2 1.4 3.8 1.0 39.6 1.4 1.1 0.9 3.1 2.8 1.6 2.3 3.1 22.1 2.6 0.0 1.7 1.2 0.3 0.2 0.2 0.2 0.1 1.4 4.3 0.4 0.1 0.2 15.0 10.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.7 0.3 0.1 0.0 0.3 4.5 0.1 0.0 1.5 0.5 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 1.8 6.9 0.1 15.4 0.1 16.3 0.8 0.1 0.1 0.9 23.8 22.4 0.3 1.4 0.2 1.7 0.0 0.4 0.0 2.3 0.2 0.1 0.2 0.0 0.2 0.1 0.2 0.8 0.2 0.1 0.1 4.3 0.0 1.4 0.0 1.2 2.4 0.0 0.2 1.4 3.0 0.1 1.4 0.1 0.2 1.4 0.4 8.0 7.3 31.1 17.5 9.9 5.6 6.0 4.0 8.3 3.1 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060889-238099413 "Enzymes, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055760 Uncertain Approved "Golgi apparatus" 110000 "Golgi apparatus" "HPA055760: " "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 4.1 3.8 6.0 6.3 7.4 5.3 3.6 10.2 7.4 4.3 6.3 11.1 5.7 9.8 8.4 8.3 4.5 4.6 5.4 6.5 7.3 6.8 9.9 24.1 4.0 6.5 9.6 4.7 6.3 22.7 5.2 5.1 2.6 6.6 5.0 4.3 6.4 4.5 5.6 5.1 2.8 9.6 5.1 9.4 5.6 3.9 15.3 6.1 8.9 8.1 6.3 5.3 4.6 4.0 5.0 5.7 6.9 5.6 4.2 8.1 4.3 5.7 9.8 6.2 16.6 5.1 3.4 12.6 5.9 2.9 6.2 7.6 6.4 4.7 9.6 1.7 3.4 8.4 24.4 12.4 5.9 10.9 21.9 11.1 13.1 22.0 9.5 9.2 9.6 3.8 6.2 11.6 13.4 11.5 19.3 2.8 6.3 8.6 9.1 17.0 20.1 8.1 10.7 12.0 9.5 5.9 2.0 7.1 15.2 6.4 10.3 10.4 3.3 13.6 5.0 9.4 6.1 12.5 12.4 6.8 6.2 4.8 5.8 18.7 7.4 2.0 5.3 6.9 4.7 4.3 3.7 5.0 5.7 8.1 5.7 3.5 4.3 4.2 0.9 4.2 5.6 1.2 5.3 4.3 6.0 7.4 10.2 7.4 7.3 6.8 9.6 4.7 6.6 6.1 SETD5 FLJ10707 ENSG00000168137 "SET domain containing 5" Q9C0A6 3 9397615-9479240 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Autism, Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017093, HPA035574" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017093: , HPA035574: " "unprognostic (6.46e-2)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" "unprognostic (7.99e-2)" "prognostic unfavourable (6.21e-4)" "unprognostic (5.52e-2)" "unprognostic (2.29e-1)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (4.04e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (6.65e-2)" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (5.15e-3)" 18.9 21.9 33.1 18.2 29.1 13.2 40.9 58.0 38.9 21.7 20.7 15.4 22.1 14.0 24.0 27.0 20.7 22.0 18.4 18.3 29.6 13.8 15.4 22.1 26.5 29.8 23.0 30.1 29.7 22.7 25.6 31.4 23.0 25.1 20.6 20.4 16.7 22.3 22.7 16.6 29.0 19.8 24.1 22.8 22.5 18.7 21.3 26.6 21.0 25.9 14.8 24.2 20.4 37.5 3.7 4.0 4.7 2.0 4.3 4.1 1.0 9.8 11.8 24.4 11.0 14.4 15.0 58.1 9.7 13.1 14.1 16.2 11.7 12.2 21.4 5.8 14.1 8.2 22.7 12.8 15.6 15.0 11.3 20.9 19.9 10.9 14.6 15.9 13.9 14.5 20.9 21.3 25.3 14.9 20.4 14.1 12.0 14.4 14.0 13.3 18.4 9.6 16.4 19.2 9.5 11.0 15.8 9.7 15.2 14.1 11.7 8.7 15.6 11.7 17.6 14.8 17.0 8.0 11.5 10.2 12.8 35.7 10.6 11.5 13.9 2.3 2.0 1.7 3.8 1.2 2.5 3.4 2.5 4.1 1.3 3.7 2.4 2.2 4.7 4.3 1.4 4.0 1.0 1.0 33.1 29.1 58.0 38.9 29.6 13.8 23.0 30.1 25.1 26.6 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell line enhanced" "Detected in many" "HHSteC: 50.1;RPTEC TERT1: 76.9;SK-MEL-30: 49.8;TIME: 59.8;U-266/84: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: " "unprognostic (2.05e-2)" "prognostic favourable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.6 2.1 0.9 12.3 25.7 16.1 13.2 1.9 1.7 2.0 1.8 12.7 0.4 1.1 1.9 11.9 0.0 0.5 0.1 30.7 1.4 50.1 0.1 1.1 12.9 12.4 15.8 20.6 27.0 3.9 31.4 5.7 0.1 0.1 0.4 0.7 1.3 0.3 1.4 0.2 76.9 0.2 0.3 3.0 38.7 0.1 49.8 0.0 0.3 59.8 4.7 2.0 28.9 2.7 5.9 54.8 6.3 4.4 1.9 6.3 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 SGK2 ENSG00000101049 "SGK2, serine/threonine kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1;kidney: 39.1;liver: 32.9" "Group enriched" "Detected in some" 5 "A549: 13.5;CAPAN-2: 10.6;EFO-21: 5.4;Hep G2: 13.7;RPTEC TERT1: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm Nucleoplasm "HPA008859: , HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favourable (5.65e-4)" 11.4 0.7 2.8 4.3 9.9 0.2 3.1 1.0 10.2 1.4 21.3 33.1 0.9 17.8 1.0 19.7 0.7 1.6 7.9 0.7 4.3 2.5 39.1 32.9 0.6 0.5 6.9 5.1 3.2 14.1 0.5 1.7 0.5 13.7 1.4 23.4 0.0 0.9 1.8 0.4 3.2 20.7 1.0 14.2 0.7 11.9 1.0 6.0 0.0 1.0 0.2 0.2 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 10.6 0.0 5.4 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 13.7 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 19.4 2.2 0.1 0.5 0.0 0.9 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 9.9 1.0 10.2 4.3 2.5 6.9 5.1 13.7 6.0 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66667596-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Supported Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favourable (5.52e-6)" "prognostic favourable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favourable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 6.5 5.9 13.9 8.7 20.9 7.7 23.9 9.8 14.8 12.0 10.0 24.0 8.7 8.6 8.0 10.3 7.6 7.8 7.8 5.4 16.1 10.2 14.9 13.6 9.9 8.5 28.8 9.3 9.8 15.6 29.2 14.8 5.9 14.6 7.8 10.7 17.2 7.0 7.7 6.1 12.4 10.8 6.0 32.8 8.2 7.2 8.9 21.9 8.3 17.3 4.3 6.8 6.1 8.0 5.8 13.8 21.4 15.7 6.9 13.3 8.0 11.4 2.9 0.5 1.8 3.5 6.8 6.5 7.3 6.9 4.0 4.2 5.2 7.7 8.6 1.8 8.0 3.7 6.0 4.3 5.0 4.8 10.2 7.8 2.1 5.1 3.5 7.0 9.3 3.3 3.8 1.9 6.7 6.4 1.5 4.2 7.6 1.8 5.5 4.3 1.6 4.0 9.7 4.3 5.8 5.4 2.6 2.5 1.9 3.3 4.9 11.0 23.1 14.0 7.6 3.8 3.4 3.3 2.7 5.2 9.9 9.9 4.4 11.8 3.9 21.4 15.7 6.2 8.1 9.3 13.3 3.7 8.4 8.5 13.8 5.8 9.0 6.9 2.5 6.9 4.4 7.7 5.3 8.0 13.9 20.9 9.8 14.8 16.1 10.2 28.8 9.3 14.6 21.9 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094256-169271105 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.9;myeloid DC: 3.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;monocytes: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074783 Approved Supported "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA074783: " "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favourable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 15.2 4.8 13.8 7.2 11.8 3.7 11.1 2.5 12.7 7.5 17.2 15.9 10.8 15.7 6.8 7.2 7.1 6.9 19.7 7.8 17.8 9.3 14.6 9.6 11.3 3.7 13.0 10.9 11.9 12.0 5.2 7.8 8.6 10.3 17.2 16.0 10.7 20.9 10.7 16.2 6.8 17.2 8.8 11.7 4.5 27.6 7.0 11.3 0.9 23.1 7.6 5.5 9.4 6.3 0.4 3.4 0.0 8.5 0.3 0.0 0.7 7.3 6.2 5.6 16.2 6.1 7.6 7.3 20.6 10.0 15.4 7.1 6.1 8.9 0.0 1.0 21.4 4.9 4.5 8.1 17.0 0.0 2.6 4.3 14.1 3.2 13.8 1.5 0.1 4.5 4.5 13.1 10.4 9.4 0.0 0.0 14.2 3.0 1.5 1.4 2.8 5.3 2.3 1.8 0.3 7.0 5.8 4.2 5.1 5.2 8.0 2.0 2.6 0.6 8.5 7.3 5.7 12.1 7.2 0.5 0.0 0.0 8.2 1.5 8.7 0.0 1.4 0.0 0.0 5.9 0.0 0.4 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.3 8.5 0.2 0.0 0.7 13.8 11.8 2.5 12.7 17.8 9.3 13.0 10.9 10.3 11.3 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936579-146081791 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 40.8" "Cell line enhanced" "Detected in some" "A-431: 10.5;CACO-2: 35.8;HBEC3-KT: 11.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basal ganglia: 11.5;cerebral cortex: 2.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.4;T-cells: 1.6" "Region enriched" "Detected in single" 14 "basal ganglia: 23.9" "Region enhanced" "Detected in many" "basal ganglia: 14.5" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA035903: AB_10696515, HPA058119: " "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 2.6 0.6 1.2 6.2 11.5 0.0 2.9 0.2 2.9 6.4 19.1 0.4 0.4 9.2 2.9 2.2 22.2 3.6 40.8 23.5 0.8 0.3 0.8 4.6 1.9 0.0 0.3 1.1 1.0 14.3 0.0 3.3 0.3 0.1 2.2 8.5 0.9 16.9 1.0 21.7 33.1 21.4 1.2 0.5 0.2 11.9 6.4 0.6 0.6 3.8 19.6 16.1 0.9 10.0 0.0 1.4 0.3 0.1 0.0 1.6 0.3 10.5 2.9 0.1 0.6 0.0 0.0 0.0 0.1 0.8 2.2 0.9 35.8 9.9 0.0 5.6 0.4 9.8 0.0 11.5 2.1 0.1 0.1 0.0 4.2 4.8 0.6 0.0 0.0 0.1 6.2 3.3 7.9 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.8 0.0 0.1 0.0 4.6 1.0 0.0 0.0 0.6 0.2 0.2 3.4 0.0 5.0 0.4 9.2 0.8 3.4 0.0 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.0 1.2 0.0 0.0 0.0 1.6 0.7 1.4 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.8 0.3 1.2 11.5 0.2 2.9 0.8 0.3 0.3 1.1 0.1 0.6 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129348-109504632 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 13.8;RPMI-8226: 13.2;TIME: 15.3;U-266/84: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA044822: , HPA048444: " "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavourable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 17.4 5.6 2.7 3.4 4.4 0.6 18.3 1.7 5.4 5.3 3.6 3.3 2.5 1.0 5.5 2.2 3.4 4.8 5.6 6.4 3.0 2.1 2.5 0.8 6.0 2.9 4.3 1.5 3.0 1.8 0.6 2.6 6.5 3.8 3.4 1.6 4.6 2.4 5.9 6.4 2.9 2.3 4.6 2.8 2.0 2.7 4.3 2.9 1.5 3.4 3.6 4.0 4.6 3.4 0.4 0.4 1.8 0.2 0.0 0.6 0.3 0.0 0.0 0.1 1.4 6.3 4.8 0.0 2.8 8.2 2.1 0.8 0.7 0.0 0.0 2.1 2.0 0.0 0.1 1.2 0.9 0.0 2.8 0.0 0.1 0.0 13.8 0.0 0.0 8.3 1.9 9.6 4.3 7.6 0.0 7.9 4.8 0.0 0.0 4.2 0.7 7.9 1.7 0.0 13.2 0.0 0.0 0.4 1.7 0.0 0.0 0.3 0.1 0.0 15.3 2.7 8.2 7.8 3.6 2.7 17.8 0.0 0.0 4.1 3.7 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 0.6 1.8 0.0 0.0 0.4 0.0 0.3 2.7 4.4 1.7 3.3 3.0 2.1 4.3 1.5 3.8 2.9 SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA034950" Approved Approved Mitochondria Mitochondria "HPA034854: AB_10964488, HPA034950: " "unprognostic (3.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.61e-3)" "unprognostic (1.53e-2)" "unprognostic (7.40e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (5.03e-1)" "unprognostic (7.90e-2)" "unprognostic (6.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" 10.9 7.3 8.3 11.0 10.0 5.5 10.4 38.0 11.5 10.6 8.0 4.5 10.8 6.0 14.1 9.2 8.5 9.8 6.7 7.2 7.2 4.2 8.4 6.5 7.1 9.0 7.6 5.9 18.8 8.7 11.4 19.7 6.6 8.5 8.3 7.4 7.3 10.2 13.7 11.4 13.9 8.2 11.0 10.3 8.8 8.5 10.7 8.7 8.4 12.5 7.2 8.0 10.7 11.5 6.7 4.8 4.4 2.4 3.4 4.3 1.2 2.9 2.3 11.4 6.7 5.3 5.7 5.5 3.5 2.9 4.4 5.7 5.2 2.1 10.4 4.4 2.7 5.1 7.0 5.0 5.8 4.7 8.0 10.5 5.2 4.4 4.0 22.0 6.5 3.9 5.8 4.1 6.0 4.7 14.6 5.9 3.7 2.6 14.1 8.2 7.7 4.0 10.2 17.8 3.5 6.0 2.9 9.4 6.6 6.3 5.8 3.9 3.1 10.6 5.2 2.8 5.3 5.5 4.1 4.8 6.8 12.4 2.9 9.5 4.3 1.6 2.3 4.4 4.3 2.4 3.7 3.9 3.6 2.9 2.7 6.7 4.1 3.3 0.1 3.4 2.4 4.8 3.3 1.2 8.3 10.0 38.0 11.5 7.2 4.2 7.6 5.9 8.5 8.7 SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078495 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 123 "intestine: 181.4" "Cell line enhanced" "Detected in some" "BEWO: 2.8;CACO-2: 4.0;HeLa: 3.1;NB-4: 3.3;RPMI-8226: 4.8;SH-SY5Y: 2.9" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011897 Enhanced "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" 0.1 0.1 0.1 1.4 0.1 0.0 0.1 0.1 0.1 0.1 93.3 0.0 0.0 94.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 5.4 0.0 0.1 0.0 0.1 0.1 181.4 0.0 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 32.6;ASC TERT1: 33.9;HSkMC: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" 1800000 "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favourable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favourable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 9.0 12.3 9.0 6.7 13.4 1.9 8.2 8.2 16.8 7.0 46.7 15.7 7.3 16.8 5.9 17.8 10.2 9.9 8.4 23.0 10.3 17.6 42.5 28.3 10.7 2.8 18.2 8.1 5.1 11.2 32.4 13.1 7.8 31.4 10.7 51.7 9.9 15.9 8.3 17.3 6.7 25.5 5.4 19.9 7.9 9.3 5.6 8.1 1.9 46.1 11.1 7.0 9.8 4.7 2.7 4.1 8.6 5.8 1.2 4.3 3.2 3.1 4.9 2.9 12.5 32.6 33.9 7.6 6.0 8.5 1.5 0.9 3.7 21.7 1.9 8.8 7.5 6.1 4.5 6.6 1.5 9.0 1.4 3.0 1.5 3.9 15.4 0.5 2.7 36.3 9.0 4.1 6.2 10.8 2.4 13.5 5.2 5.7 0.2 1.4 1.8 10.2 1.1 0.1 3.3 18.6 4.4 1.0 1.9 16.3 6.7 2.8 13.1 2.9 12.0 8.7 1.6 9.6 1.4 3.6 2.6 0.4 3.1 1.6 3.5 8.6 5.6 0.3 1.9 4.2 2.2 2.4 3.1 2.0 4.1 2.7 4.3 3.4 1.2 1.2 5.8 2.5 2.2 3.2 9.0 13.4 8.2 16.8 10.3 17.6 18.2 8.1 31.4 8.1 SIAH1 hSIAH1 ENSG00000196470 "Siah E3 ubiquitin protein ligase 1" Q8IUQ4 16 48356364-48448402 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 102.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018724 Enhanced Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB018724: AB_2188865" "unprognostic (7.08e-2)" "unprognostic (1.16e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-3)" "unprognostic (1.25e-2)" "unprognostic (7.93e-3)" "unprognostic (1.12e-2)" "unprognostic (9.22e-3)" "unprognostic (3.26e-1)" "unprognostic (8.02e-2)" "unprognostic (7.84e-3)" "unprognostic (7.67e-3)" "unprognostic (4.38e-2)" "unprognostic (4.00e-1)" "unprognostic (9.55e-2)" "unprognostic (1.26e-2)" 20.6 11.4 11.9 11.0 13.5 19.2 25.5 15.5 16.6 14.6 13.1 15.0 6.5 12.8 16.8 13.4 12.7 12.9 12.9 11.4 12.6 11.6 12.1 17.5 13.9 10.0 12.8 11.6 16.7 11.4 13.1 9.1 102.6 14.1 14.2 12.2 32.1 13.2 12.1 17.0 16.6 16.0 18.6 12.7 11.3 12.5 17.9 13.0 17.5 14.5 9.3 11.5 15.9 14.8 12.6 8.3 21.9 5.2 5.3 6.1 3.5 8.4 7.6 16.6 14.9 14.3 12.5 17.0 7.9 10.8 11.8 5.8 5.8 11.1 11.0 8.8 10.0 9.9 11.4 11.6 14.6 4.4 9.2 5.9 6.0 15.1 20.0 5.8 9.1 15.0 20.9 6.9 16.1 9.9 9.5 10.5 9.6 5.8 15.6 11.9 20.2 11.8 18.2 25.0 11.6 11.0 10.7 18.9 16.8 23.6 11.8 20.3 7.5 13.4 10.5 12.7 11.4 6.8 8.4 13.7 5.7 20.2 9.4 7.2 11.4 6.9 5.2 21.9 2.7 2.2 3.0 12.6 3.0 4.2 8.3 12.1 6.1 4.5 2.9 5.3 1.3 7.9 1.6 3.5 11.9 13.5 15.5 16.6 12.6 11.6 12.8 11.6 14.1 13.0 SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741127-150763477 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: " "prognostic favourable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavourable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" 9.6 48.0 7.6 11.8 10.3 22.7 23.5 10.9 17.2 30.0 10.5 8.4 20.3 7.9 23.5 13.9 28.8 14.9 11.0 10.7 7.2 7.3 8.4 35.5 11.8 19.1 9.9 7.5 19.0 14.6 6.4 8.1 31.4 7.9 18.8 9.2 8.3 11.2 21.7 8.3 19.3 9.5 17.4 9.4 16.9 12.0 8.7 8.6 23.6 11.4 10.6 25.1 22.7 25.6 3.0 3.1 10.0 2.7 1.6 3.6 1.1 16.6 4.1 3.2 6.4 11.1 8.4 13.1 6.9 8.0 8.4 10.3 8.4 7.5 9.3 10.2 7.2 10.3 8.7 6.2 7.9 7.8 6.2 18.2 5.0 27.9 15.9 10.0 5.4 7.6 14.5 5.0 11.5 6.5 4.5 36.7 5.3 20.0 18.3 5.1 10.5 8.2 13.5 7.0 33.3 5.3 5.8 12.5 5.9 5.2 4.9 12.3 32.9 15.1 4.5 5.8 5.2 12.6 9.3 43.7 16.6 13.0 5.5 14.5 2.9 9.5 2.7 10.0 2.1 1.5 3.2 2.5 3.6 3.2 2.4 3.0 1.9 1.9 5.9 1.6 1.5 3.1 2.0 1.1 7.6 10.3 10.9 17.2 7.2 7.3 9.9 7.5 7.9 8.6 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016026 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA016026: AB_1857321" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favourable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favourable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.8 3.9 6.8 7.3 34.0 10.1 4.0 5.1 7.3 3.9 4.5 13.1 6.2 4.6 7.1 5.9 8.3 5.3 3.8 5.1 3.4 2.2 5.0 3.4 6.4 7.4 4.8 3.3 9.8 5.7 5.7 7.4 4.6 4.6 6.7 6.1 2.7 5.0 4.4 2.3 3.9 6.7 7.3 5.5 8.7 5.3 3.2 7.5 7.5 3.1 3.0 7.5 3.9 6.4 8.6 5.2 5.5 7.0 1.9 1.5 9.7 2.8 6.8 5.8 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 SIK3 "FLJ12240, KIAA0999, L19, QSK" ENSG00000160584 "SIK family kinase 3" 11 116843402-117098437 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045245, HPA048161" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA045245: , HPA048161: " "unprognostic (3.19e-2)" "unprognostic (3.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-2)" "unprognostic (1.28e-3)" "unprognostic (1.89e-1)" "prognostic favourable (1.12e-5)" "unprognostic (1.82e-1)" "unprognostic (6.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" 13.0 12.2 24.7 13.8 36.9 14.3 13.5 24.0 34.4 13.5 16.6 40.5 10.4 10.9 18.6 9.9 13.7 16.6 12.8 16.0 23.7 16.2 13.9 17.6 13.7 11.9 25.8 24.4 22.4 19.5 29.4 18.4 16.3 23.9 11.4 11.7 10.6 11.7 15.6 16.9 11.3 14.0 18.4 17.2 14.2 14.5 26.0 38.0 10.4 22.1 6.9 12.9 14.5 12.9 2.4 1.7 3.9 3.7 1.6 1.8 0.7 7.7 6.0 9.6 10.1 8.3 8.9 15.3 5.9 10.7 4.7 5.3 14.6 9.0 9.2 9.7 10.9 12.2 7.9 8.6 6.6 25.3 5.0 20.7 6.6 9.0 7.7 7.4 8.2 9.8 5.0 10.0 16.2 6.2 9.9 6.9 6.4 2.6 6.6 8.0 5.3 4.5 8.5 5.5 7.3 6.5 1.5 9.3 7.5 16.0 7.0 3.2 4.6 7.8 7.1 5.8 7.4 9.6 5.9 4.9 3.5 11.8 5.4 12.2 7.8 3.9 1.1 0.0 1.0 1.5 1.8 0.4 0.9 0.4 1.7 2.4 0.3 0.1 2.6 1.6 3.7 0.1 0.1 0.7 24.7 36.9 24.0 32.2 23.7 16.2 25.8 24.4 23.9 38.0 SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB004506: AB_2187766, HPA047213: AB_2679984, HPA062123: AB_2684689" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (3.52e-1)" 21.0 15.4 14.0 19.4 18.5 31.6 20.4 26.3 15.5 26.3 20.2 19.9 15.3 11.8 26.6 16.8 17.7 22.1 15.9 13.4 14.2 11.8 13.6 13.9 17.4 20.7 13.0 14.2 27.6 19.8 23.4 16.8 17.2 13.0 22.9 14.3 23.0 17.6 20.5 18.2 23.5 17.9 24.5 12.8 20.3 16.8 28.5 15.1 48.7 24.0 12.8 26.9 26.0 19.0 9.8 6.5 9.3 8.3 9.7 12.7 6.3 12.7 26.4 23.6 15.5 11.8 12.5 13.7 9.6 14.9 14.1 15.2 14.6 17.3 27.8 10.0 14.1 22.8 34.2 14.4 15.5 22.4 17.7 26.2 20.1 11.4 8.9 24.8 22.4 15.1 11.1 16.4 17.2 12.6 20.6 31.0 11.4 14.8 24.3 15.9 23.0 11.1 24.6 31.3 17.1 10.1 23.4 18.7 18.7 23.6 10.6 13.2 16.1 19.7 11.0 17.5 23.7 11.5 14.1 21.3 33.4 29.5 10.4 25.4 9.7 3.3 4.8 6.9 8.5 4.8 12.7 9.3 10.8 10.7 6.5 9.8 11.1 9.5 9.3 9.7 8.3 4.4 9.5 6.3 14.0 18.5 26.3 15.5 14.2 11.8 13.0 14.2 13.0 15.1 SIN3B KIAA0700 ENSG00000127511 "SIN3 transcription regulator family member B" O75182 19 16829400-16880353 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050329 Uncertain Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA050329: " "unprognostic (2.71e-3)" "unprognostic (8.89e-2)" "unprognostic (1.32e-3)" "unprognostic (6.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.05e-2)" "unprognostic (5.44e-2)" "unprognostic (9.89e-2)" "unprognostic (5.42e-3)" "unprognostic (2.77e-1)" "prognostic favourable (4.37e-4)" "prognostic unfavourable (3.58e-4)" "unprognostic (1.18e-3)" "unprognostic (8.45e-2)" "unprognostic (1.49e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" 19.1 17.9 22.2 17.2 28.1 9.8 21.5 25.1 38.6 24.4 16.0 20.8 50.0 12.8 37.5 21.5 14.5 23.3 17.3 15.7 24.2 20.8 15.9 9.8 21.7 20.8 16.5 30.4 32.5 16.2 60.8 17.7 53.2 24.8 22.7 11.0 15.5 20.2 54.7 17.1 22.7 17.7 26.5 14.8 25.1 13.7 30.2 13.4 9.3 22.5 9.6 15.8 17.2 22.2 4.8 2.6 6.1 6.7 1.9 2.0 2.3 14.5 7.8 13.2 16.9 10.9 10.1 41.8 12.4 10.3 17.2 15.3 19.2 13.7 13.1 14.0 14.3 12.6 10.9 11.1 16.0 13.6 19.7 14.0 17.1 8.7 14.4 8.2 11.4 16.6 14.7 11.6 10.0 15.6 11.4 8.1 12.0 17.4 11.1 13.2 16.4 25.0 14.7 12.2 8.6 9.8 12.4 9.8 12.3 15.7 12.1 9.7 8.5 7.7 20.4 16.8 10.2 24.2 13.8 11.6 8.5 13.1 11.6 10.8 12.4 0.1 6.7 6.1 1.8 6.0 1.2 4.8 1.7 2.0 2.1 3.8 2.0 1.4 3.3 1.9 5.3 2.6 0.5 2.3 22.2 28.1 25.1 38.6 24.2 20.8 16.5 30.4 24.8 13.4 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967201-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" 17000 "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favourable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 15.2 11.2 13.7 11.0 36.7 14.6 16.1 16.7 13.1 16.6 19.0 9.9 10.9 9.1 17.0 12.1 40.2 12.1 13.6 17.2 10.6 7.1 14.9 12.2 17.1 10.1 11.2 13.4 17.2 12.5 22.6 13.1 17.4 12.8 19.3 13.6 11.4 19.8 12.7 19.3 16.6 15.5 29.8 13.0 12.1 15.7 10.2 12.8 12.0 15.8 21.6 12.5 24.9 23.6 1.4 2.2 6.5 1.4 1.3 3.6 0.7 21.2 12.4 14.9 10.6 16.1 22.5 6.3 13.3 17.7 9.9 9.3 7.9 22.9 11.3 8.3 13.7 23.2 7.8 16.8 14.5 9.0 10.8 11.5 10.2 6.6 12.1 13.7 10.0 11.5 22.1 13.4 39.2 17.8 14.3 7.8 13.0 7.4 9.6 7.6 3.7 8.0 9.4 18.3 5.8 13.0 24.5 3.5 6.1 11.5 11.2 11.0 5.8 9.9 26.9 7.3 7.6 13.4 15.5 9.5 11.6 7.2 10.8 18.4 4.7 1.2 1.4 3.3 3.6 1.2 3.6 1.1 2.2 2.2 1.2 1.4 1.5 2.5 6.5 1.3 1.0 2.2 1.4 0.7 13.7 36.7 16.7 13.1 10.6 7.1 11.2 13.4 12.8 12.8 SMARCD3 "BAF60C, CRACD3, Rsc6p" ENSG00000082014 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" Q6STE5 7 151238764-151277896 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.2" "Cell line enhanced" "Detected in many" "AN3-CA: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 3.1;monocytes: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063955, HPA065517" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA063955: , HPA065517: " "unprognostic (1.23e-2)" "unprognostic (2.03e-1)" "prognostic unfavourable (5.50e-4)" "unprognostic (4.38e-3)" "unprognostic (4.67e-1)" "unprognostic (1.41e-3)" "unprognostic (2.24e-2)" "unprognostic (3.52e-2)" "unprognostic (1.63e-1)" "unprognostic (3.50e-1)" "unprognostic (2.08e-3)" "unprognostic (9.18e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.35e-3)" "unprognostic (1.29e-1)" 9.7 16.0 34.2 4.0 40.3 4.9 9.8 25.4 36.8 12.9 5.6 7.8 7.9 2.9 8.6 11.4 6.7 14.5 10.7 38.5 22.2 24.7 4.9 2.0 8.3 4.0 18.7 18.8 19.2 7.5 6.8 14.7 4.6 13.3 10.8 3.6 7.6 6.6 18.1 75.2 5.7 3.4 10.0 14.1 4.3 4.8 9.0 11.6 0.0 7.4 9.5 2.5 10.1 4.8 0.2 2.6 3.1 8.8 0.0 0.8 2.1 0.3 2.8 9.4 33.2 14.9 6.7 0.7 6.1 6.2 3.6 2.1 2.1 1.9 3.6 2.2 9.6 0.6 7.5 0.6 1.4 1.1 4.6 0.0 1.9 0.6 12.9 0.1 6.0 15.9 0.8 1.2 0.1 0.7 7.1 1.2 18.9 3.8 0.6 4.7 2.9 1.2 0.2 14.7 0.1 3.2 0.0 5.4 10.9 5.7 1.0 4.4 0.8 9.2 1.1 2.3 3.7 7.1 2.0 7.8 0.0 2.9 6.6 8.2 10.3 0.6 8.8 0.0 0.2 1.9 0.1 0.2 0.8 0.0 2.6 0.0 0.5 0.8 3.1 0.0 0.4 0.0 0.7 2.1 34.2 40.3 25.4 27.9 22.2 24.7 18.7 18.8 13.3 11.6 SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1, nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804853-18926454 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported Nucleoplasm Nucleoplasm "HPA006870: AB_1079725, HPA031623: , HPA073972: " "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (5.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (8.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" 4.7 3.0 2.1 4.5 3.5 11.7 6.2 13.2 3.0 4.4 4.5 3.1 5.4 5.1 5.5 4.0 3.0 4.5 2.3 2.2 4.6 5.4 4.1 6.2 2.3 6.3 4.5 7.2 3.9 3.1 4.2 5.0 4.7 3.3 21.1 14.4 5.0 3.9 3.4 4.5 4.3 4.0 6.0 5.8 5.2 4.9 7.1 4.6 19.1 5.6 2.3 6.1 1.0 23.2 15.6 14.7 10.4 16.9 17.9 10.9 10.9 10.7 11.9 13.3 13.7 8.6 32.1 15.7 15.1 13.3 16.9 9.5 19.0 20.6 10.6 14.6 13.7 17.5 13.7 19.6 11.6 10.5 16.1 24.5 29.6 16.6 22.4 17.9 13.1 12.4 13.5 11.8 15.7 9.0 15.7 19.8 11.0 10.2 18.3 13.4 10.2 16.9 11.5 11.9 9.2 12.5 21.0 17.9 12.0 11.0 16.1 9.2 11.9 21.2 11.9 15.3 10.6 19.1 2.5 3.4 6.1 2.8 2.9 3.7 4.0 4.3 2.5 7.1 5.4 4.7 7.6 2.3 5.6 4.6 3.7 1.0 SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027438-99144100 "Enzymes, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Uncertain Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA019671: , HPA055245: " "unprognostic (2.21e-1)" "unprognostic (6.15e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.81e-1)" "unprognostic (4.62e-2)" 15.0 11.1 8.7 10.5 15.0 23.8 12.4 12.1 16.5 11.8 10.9 20.9 6.9 9.5 11.6 5.7 19.3 10.2 12.5 7.9 9.3 8.4 10.3 10.1 16.0 8.1 15.4 9.4 19.6 22.5 9.0 15.1 15.4 14.9 11.7 10.6 14.3 13.4 9.6 10.7 17.3 10.3 9.8 10.6 9.1 19.5 26.0 11.8 6.6 7.8 6.6 12.7 11.5 13.3 1.2 1.2 2.4 1.9 1.0 2.1 0.6 13.8 7.9 6.4 4.6 5.1 5.4 9.6 7.8 7.5 6.3 5.9 4.0 11.5 4.3 8.4 7.2 7.6 3.6 10.0 6.6 3.3 3.0 2.3 4.6 3.8 4.8 2.6 5.7 4.9 7.0 9.9 11.5 6.0 7.0 7.7 5.8 11.2 4.5 5.5 7.5 8.5 4.3 6.0 2.6 6.9 11.4 2.8 6.4 7.4 9.8 6.8 3.1 5.0 8.7 10.0 10.3 17.9 15.4 6.9 4.7 4.6 5.0 5.2 15.5 2.0 1.4 2.3 1.3 1.5 1.6 0.9 2.1 1.3 1.1 1.2 1.2 1.0 2.4 1.0 1.9 1.2 2.0 0.6 8.7 15.0 12.1 16.5 9.3 8.4 15.4 9.4 14.9 11.8 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542295-64662068 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 54.0;HBF TERT88: 41.5;LHCN-M2: 41.5;TIME: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA071508: " "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 12.3 9.2 10.5 9.0 15.0 11.5 10.2 16.7 10.0 9.2 9.1 11.5 8.1 9.3 7.9 6.9 7.6 7.8 10.5 8.2 12.6 4.6 9.4 5.7 19.0 8.6 9.5 4.8 8.5 9.0 8.2 10.7 15.3 10.1 10.6 8.2 9.6 9.9 7.6 7.5 11.0 13.7 8.9 6.6 9.9 9.8 21.6 10.6 8.9 11.4 4.1 9.6 9.4 11.7 3.0 3.0 4.8 2.2 7.3 3.5 1.7 15.6 4.3 3.7 2.8 2.6 10.0 1.8 54.0 24.6 21.1 18.4 2.4 12.0 2.1 3.4 9.2 3.5 3.5 9.3 41.5 1.1 2.3 2.2 2.6 2.9 2.3 2.9 1.4 2.7 3.6 29.3 11.2 24.3 3.2 2.1 41.5 3.4 6.7 1.3 2.2 5.7 1.5 9.0 1.3 5.8 2.8 3.5 3.1 3.3 1.7 2.5 2.8 2.3 47.8 24.0 13.0 9.2 35.8 2.4 2.8 3.8 5.9 1.7 7.2 2.8 2.2 4.8 3.3 2.0 2.8 2.0 2.4 3.5 3.0 3.0 2.3 2.6 4.4 7.3 1.0 2.6 1.1 1.7 10.5 15.0 16.7 10.0 12.6 4.6 9.5 4.8 10.1 10.6 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 50.8;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favourable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favourable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.2 2.0 3.7 3.5 11.1 4.0 3.5 3.5 5.9 3.8 3.8 2.7 4.7 5.1 2.8 4.4 2.1 4.3 7.5 4.0 5.9 3.5 5.9 3.7 3.1 5.8 6.6 6.6 4.4 5.2 4.3 7.4 50.8 2.6 6.0 3.5 1.7 6.6 5.8 4.1 9.1 4.6 2.7 5.4 9.9 5.6 2.6 5.5 3.0 3.3 4.2 2.2 8.4 29.5 3.4 3.4 3.9 4.1 9.7 6.9 4.4 2.4 7.9 4.8 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023104-45077185 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 66.3;liver: 98.4;thyroid gland: 116.3" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 72.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "eosinophil: 36.4" "Lineage enriched" "Detected in many" 13 "granulocytes: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol 430000 Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favourable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 1.4 10.2 3.0 1.5 3.2 1.0 7.1 3.1 3.8 66.3 5.5 6.2 39.2 2.6 2.6 3.2 6.7 3.5 3.9 3.4 3.0 3.0 20.9 98.4 1.6 2.2 4.2 2.3 1.6 7.3 1.2 1.8 0.5 5.0 48.5 3.8 2.3 7.6 46.7 1.4 8.0 8.7 2.0 5.0 2.4 5.6 2.5 3.9 3.1 116.3 3.8 3.5 4.2 4.4 1.6 2.4 36.4 2.7 0.4 1.0 1.3 15.8 13.9 3.5 11.4 3.1 5.4 3.7 4.4 3.0 10.0 8.5 11.5 8.6 2.0 9.9 5.4 23.8 18.2 16.6 8.0 34.3 11.3 15.9 18.2 25.5 2.3 27.5 26.6 6.9 12.6 5.7 9.2 9.3 17.7 5.6 9.4 6.3 16.6 14.9 13.6 14.8 0.0 23.0 7.7 7.3 15.4 25.0 13.1 8.9 14.1 6.7 20.3 11.3 8.3 8.0 7.0 17.8 10.5 1.0 6.9 2.0 12.9 24.4 20.7 5.0 2.7 36.4 0.6 2.5 1.0 1.2 0.6 0.8 2.4 1.6 0.5 0.6 1.4 0.4 2.5 1.3 0.6 1.3 3.0 3.2 3.1 3.8 3.0 3.0 4.2 2.3 5.0 3.9 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell line enhanced" "Detected in many" "U-138 MG: 14.7;U-2 OS: 15.0;U-251 MG: 13.7;U-87 MG: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 4.0 0.3 2.1 3.5 1.1 3.2 1.4 8.7 5.8 5.8 4.4 3.1 1.4 0.0 3.2 6.4 5.1 1.7 2.0 2.3 0.5 1.3 0.4 3.7 0.2 1.5 0.0 0.7 9.3 3.1 5.3 1.3 0.0 3.0 0.0 4.2 1.1 0.1 12.4 4.4 1.6 2.1 4.7 0.7 5.7 0.0 2.3 10.9 0.6 0.0 0.1 0.3 0.1 0.1 14.7 15.0 1.7 13.7 0.5 0.0 0.1 16.6 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavourable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavourable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 13.5 7.1 8.1 15.4 11.7 32.1 11.7 22.5 17.8 12.8 23.8 7.8 10.8 20.3 15.2 7.9 24.9 8.9 10.8 8.7 8.9 7.8 17.8 18.9 14.9 14.6 8.0 8.3 9.5 26.0 11.7 17.7 27.9 9.6 10.5 28.7 12.4 17.6 9.4 19.9 26.2 25.7 11.3 7.9 19.0 13.9 32.7 7.6 21.0 8.5 17.0 19.8 15.2 15.7 4.3 2.8 24.6 3.4 5.0 6.7 2.9 29.3 11.1 16.4 24.5 9.2 12.0 20.8 18.0 17.4 16.9 18.0 31.3 9.9 39.2 15.3 11.1 15.1 32.0 21.5 30.3 26.7 23.1 20.6 13.1 27.1 8.2 30.4 10.1 7.7 11.7 19.4 25.4 21.1 43.6 16.6 14.1 10.4 31.3 23.7 13.4 12.2 22.1 19.7 24.2 16.9 49.3 35.1 12.9 18.5 17.6 12.5 9.9 20.3 15.2 15.9 12.4 10.7 22.6 9.8 21.6 36.8 6.3 35.4 14.1 24.5 2.1 13.7 4.3 2.5 6.1 4.3 5.7 5.7 2.8 3.3 4.8 5.2 24.6 5.0 3.4 1.6 6.7 2.9 8.1 11.7 22.5 17.8 8.9 7.8 8.0 8.3 9.6 7.6 SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015522: AB_1857479, HPA020876: AB_1857480" "unprognostic (9.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (4.64e-2)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (7.95e-2)" "unprognostic (4.72e-2)" "unprognostic (2.87e-2)" "unprognostic (3.44e-1)" 9.9 12.1 24.8 10.1 27.6 7.1 13.3 28.4 47.1 12.7 9.4 21.0 7.8 8.2 13.2 11.9 11.9 10.9 11.6 10.4 26.4 28.6 10.3 10.1 9.2 11.5 27.2 30.2 13.0 10.5 11.9 15.3 12.0 27.3 14.0 10.9 7.9 10.1 11.1 7.9 16.9 8.2 13.3 23.1 12.0 11.3 69.3 32.3 22.1 11.3 4.7 14.0 13.6 9.7 12.2 7.3 58.2 8.1 10.0 11.9 6.0 13.1 8.7 13.9 27.6 14.9 16.9 7.8 12.8 15.1 12.9 15.1 6.8 11.2 8.3 16.4 16.6 7.9 14.1 13.6 16.5 14.4 12.5 11.8 8.2 5.9 17.3 11.2 17.7 11.7 25.3 10.9 20.6 22.1 11.6 34.2 14.2 24.8 41.5 8.5 11.5 9.6 13.5 15.4 18.2 18.6 20.4 20.5 14.2 14.6 22.0 13.5 8.2 7.8 14.5 23.8 17.4 22.6 12.0 37.6 37.0 20.5 9.3 11.6 17.7 11.2 8.1 26.0 11.9 5.5 7.1 12.2 9.0 8.9 7.3 11.6 8.5 9.7 58.2 10.0 6.2 6.4 10.1 6.0 24.8 27.6 28.4 38.7 26.4 28.6 27.2 30.2 27.3 32.3 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 73.4" "Cell line enhanced" "Detected in many" "RH-30: 30.8;U-266/70: 12.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 1.8 1.3 0.9 1.8 0.8 0.3 7.7 1.5 0.9 4.5 1.1 0.2 1.3 2.5 3.3 2.6 0.7 1.7 16.7 2.0 1.8 0.2 0.2 0.4 0.8 2.0 0.7 0.7 0.7 1.0 5.8 0.3 1.1 2.8 0.8 0.9 2.9 0.5 73.4 2.3 1.3 4.0 2.0 0.8 1.3 0.5 0.9 0.3 0.6 18.3 1.6 2.0 0.8 0.4 2.6 0.9 0.3 0.1 0.6 0.3 3.2 4.3 0.7 2.2 0.0 0.1 1.0 0.4 0.0 0.2 0.0 3.6 0.6 3.2 0.4 0.3 0.9 0.0 0.1 0.0 2.8 3.0 1.7 2.7 0.5 0.0 0.8 5.0 2.7 0.0 0.0 0.0 0.0 2.1 3.8 0.8 6.9 0.6 4.7 0.8 1.2 1.5 30.8 0.9 0.0 1.4 5.2 2.5 0.0 2.3 1.0 2.9 3.7 0.0 1.2 2.8 2.3 0.4 12.8 2.0 2.2 0.6 6.1 1.6 0.8 0.3 0.2 0.5 0.1 0.6 0.2 0.1 0.1 0.0 0.4 0.1 0.1 0.9 0.1 0.0 2.6 0.0 0.3 1.3 1.8 7.7 1.5 2.0 1.8 2.0 0.7 1.1 0.9 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavourable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.2 4.0 6.6 14.1 6.0 5.4 3.4 2.5 2.4 4.7 15.5 5.1 2.7 11.1 4.9 4.9 2.6 5.7 3.1 2.1 4.5 2.9 15.1 9.9 3.8 5.5 12.2 5.5 1.3 2.0 15.8 2.9 3.3 4.2 3.1 5.4 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.5 12.7 2.1 2.6 4.3 10.9 4.6 6.5 3.7 3.9 3.5 3.0 5.7 2.4 34.2 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain "CAB017189: , HPA057099: " "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 11.9 9.7 6.2 5.3 17.3 11.9 3.6 5.9 6.8 9.8 10.4 5.2 4.5 9.9 9.5 7.0 13.9 7.6 8.6 11.4 3.5 13.6 6.9 9.9 7.7 8.2 7.3 14.9 13.9 5.8 10.4 6.9 22.4 4.9 7.8 6.9 3.3 34.5 7.5 4.6 5.0 16.6 15.8 17.4 17.0 9.4 10.5 11.7 8.6 9.6 17.2 6.4 7.7 12.3 6.7 13.7 11.7 7.1 11.8 7.8 24.8 7.9 5.8 6.1 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 23.6;RT4: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.1 6.7 0.1 0.2 4.7 4.9 7.3 4.0 5.4 2.1 2.0 7.2 16.3 0.3 12.5 3.7 23.6 2.2 17.0 1.1 1.3 2.5 1.5 10.8 2.9 3.3 0.3 6.0 4.3 15.8 3.1 3.2 2.4 0.0 0.6 2.5 20.8 0.2 3.0 1.5 5.4 7.6 0.2 1.1 6.9 35.7 1.4 2.2 9.4 14.0 4.4 19.6 5.2 3.8 1.7 3.7 4.7 1.1 0.6 0.3 0.2 4.8 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574869 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA069290: , HPA070604: " "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 44.1 32.5 48.0 33.6 51.5 29.3 73.9 42.3 51.5 37.2 40.1 25.4 39.3 41.3 32.6 51.8 45.7 46.2 35.3 44.4 40.7 42.5 38.0 50.9 37.5 49.0 39.4 39.0 38.0 61.8 33.9 39.9 35.8 36.9 33.9 35.9 34.1 54.2 35.8 107.1 36.9 40.8 35.4 35.0 41.7 38.5 28.0 28.4 37.0 50.9 45.3 36.3 30.8 42.2 35.5 30.1 62.0 28.8 20.7 46.5 28.1 40.6 26.0 18.8 29.0 32.5 31.3 19.3 35.3 27.6 30.9 32.2 24.4 47.2 41.4 19.4 27.8 31.8 30.3 29.1 30.2 34.4 35.9 25.9 22.9 38.6 36.7 32.8 22.7 27.9 24.6 33.1 31.6 28.9 44.8 32.0 24.4 36.2 37.5 52.7 32.9 39.6 29.9 30.4 57.8 33.8 12.5 34.8 23.9 23.9 61.5 104.3 32.0 28.6 21.9 29.8 18.9 33.5 30.3 39.1 46.9 51.6 31.2 52.3 14.4 37.1 28.3 53.6 25.9 28.8 31.9 35.5 34.4 30.7 30.1 33.1 42.2 34.1 62.0 20.7 25.4 19.0 46.5 28.1 48.0 51.5 42.3 51.5 40.7 42.5 39.4 39.0 36.9 28.4 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 11000 Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: " "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 12.9 12.8 22.1 13.9 23.0 10.5 17.8 20.1 21.8 18.1 18.4 35.0 13.6 17.8 23.1 15.4 22.7 16.5 14.7 19.0 23.3 21.2 19.6 16.9 13.4 15.3 33.0 14.3 16.3 15.1 20.9 17.8 20.6 26.3 20.2 20.7 14.6 18.3 15.7 30.1 14.4 25.2 19.0 54.7 13.8 15.6 13.3 22.3 18.4 20.1 15.9 19.0 16.8 16.4 17.6 16.9 27.8 17.8 16.7 20.7 12.3 5.3 6.2 4.9 4.5 4.6 5.5 5.6 3.3 4.5 6.0 5.8 10.3 5.1 4.4 5.2 2.7 4.2 5.2 11.5 6.9 7.8 5.9 6.0 4.3 8.0 6.4 4.9 7.2 4.4 8.3 7.1 10.3 3.5 6.5 6.8 158.8 6.5 7.6 4.4 7.8 3.3 5.3 12.9 6.3 6.5 6.0 9.0 6.6 4.0 4.9 6.9 4.6 2.9 3.1 5.4 6.5 3.3 5.8 6.5 6.2 3.4 6.7 5.3 6.3 22.6 16.2 27.8 14.4 17.8 15.4 17.6 16.7 14.0 16.9 16.2 17.5 13.2 24.1 16.7 15.7 16.4 20.7 12.3 22.1 23.0 20.1 21.2 23.3 21.2 33.0 14.3 26.3 22.3 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 18.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040202 Uncertain Approved "Plasma membrane" "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 15.9 3.7 6.8 5.1 2.8 2.1 12.4 8.9 2.0 5.8 3.4 1.5 4.5 2.7 1.5 2.7 1.2 2.9 4.8 3.3 3.4 1.5 1.7 2.9 11.3 2.6 14.8 8.5 1.8 2.2 6.6 1.5 4.1 1.9 8.0 1.5 1.5 1.5 1.5 3.4 6.1 1.8 3.1 6.0 3.1 18.6 3.2 1.5 1.5 1.5 9.5 3.9 2.7 10.5 15.2 4.3 0.6 13.1 14.7 4.5 6.7 8.0 0.5 0.3 8.0 15.3 0.0 14.2 14.0 9.1 8.2 0.3 12.9 8.2 1.0 7.7 3.3 2.0 2.9 9.3 7.3 5.0 2.1 5.7 0.4 5.4 9.0 2.9 5.5 0.7 15.3 4.9 0.2 0.0 3.7 24.5 1.4 15.1 10.8 3.0 6.2 1.5 6.0 1.8 3.5 2.6 4.6 5.5 1.8 0.6 16.1 1.0 1.9 2.0 8.1 5.9 9.8 8.8 8.7 8.2 7.6 8.9 9.2 7.7 4.3 0.6 4.2 6.3 0.6 8.2 10.5 9.2 7.9 0.9 7.0 9.9 5.9 0.9 13.1 0.3 15.2 14.7 4.5 3.7 5.1 12.4 8.9 3.3 3.4 2.6 14.8 4.1 3.2 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042073-172188386 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell line enhanced" "Detected in all" "WM-115: 51.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 27.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" 24000 "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: " "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favourable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 15.0 4.7 2.6 25.8 4.4 38.3 13.5 27.5 3.0 3.6 5.0 4.8 3.4 4.7 4.4 4.4 3.6 4.2 11.0 9.0 2.4 2.5 5.3 4.5 15.4 40.9 5.4 1.9 3.5 4.1 2.5 3.7 16.2 4.5 4.3 4.0 5.6 7.8 2.5 3.1 9.0 12.2 5.7 4.6 33.0 6.2 13.1 3.5 20.6 4.6 3.1 23.7 9.5 11.3 5.0 10.3 22.3 30.8 7.4 18.0 15.6 7.7 7.2 4.5 6.7 5.2 6.5 11.5 10.1 8.4 7.3 6.8 3.7 10.2 9.3 5.4 12.4 9.0 2.0 12.3 4.8 12.2 3.3 11.2 3.0 2.1 7.5 11.3 13.3 6.4 2.6 9.9 8.3 6.3 1.0 13.1 5.1 12.4 8.1 25.5 1.8 5.7 13.4 3.5 6.2 3.0 9.8 3.0 3.7 5.8 8.1 27.6 2.9 24.0 8.7 8.2 4.1 5.7 5.4 11.1 16.3 5.9 10.8 17.5 51.5 7.1 10.8 10.0 18.0 21.4 13.3 5.0 9.4 12.8 10.3 4.4 5.6 9.6 22.3 7.4 30.8 3.2 12.2 15.6 2.6 4.4 27.5 3.0 2.4 2.5 5.4 1.9 4.5 3.5 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: " "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favourable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favourable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.1 10.2 7.8 14.7 7.4 6.7 16.5 10.3 10.8 9.7 10.4 8.3 14.8 13.9 11.5 10.8 13.7 7.6 15.9 3.0 25.9 18.7 14.2 0.6 10.5 15.9 14.2 23.8 12.2 11.6 7.5 11.1 9.7 26.5 19.1 5.5 15.8 13.7 14.4 14.9 12.6 21.7 8.3 15.5 8.8 15.5 18.1 13.0 0.0 7.7 11.1 12.1 23.4 13.1 10.1 11.4 19.7 16.4 37.6 15.8 10.4 10.0 19.0 10.3 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Approved Cytosol Cytosol "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favourable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 10.2 19.0 15.7 12.8 20.3 13.3 14.6 8.8 21.0 11.5 16.2 15.2 20.5 17.2 11.4 22.1 16.0 18.3 15.5 13.0 14.5 11.9 19.5 30.1 11.4 24.6 14.2 13.2 13.2 24.5 16.5 15.1 14.0 13.3 14.3 13.7 12.8 19.0 16.3 9.9 12.2 14.2 11.5 12.3 15.9 16.8 18.9 12.7 27.2 19.8 12.8 17.0 12.9 10.3 7.9 7.8 5.8 7.6 14.5 11.2 9.7 7.3 9.6 8.4 7.2 21.2 20.7 9.7 9.5 13.1 8.1 8.1 11.2 16.4 4.2 13.3 15.7 7.6 9.8 15.7 4.3 10.4 11.4 9.6 8.7 9.6 19.2 9.1 11.2 22.0 25.3 11.1 29.4 9.8 11.9 11.6 13.8 13.5 9.9 19.8 7.9 5.9 9.3 9.5 12.4 16.8 8.5 6.8 8.7 3.4 13.5 19.3 14.1 19.2 7.5 11.0 7.8 8.9 9.0 14.3 6.1 10.1 12.2 9.6 9.6 2.0 7.6 5.8 6.0 4.2 6.8 7.8 7.5 11.2 7.8 7.9 7.8 10.0 5.2 14.5 3.6 6.7 8.4 9.7 15.7 20.3 8.8 21.0 14.5 11.9 14.2 13.2 13.3 12.7 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA018138, HPA037979" Uncertain Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.5 5.7 5.2 3.5 6.5 8.6 2.1 16.5 17.8 9.0 9.2 4.9 3.3 7.3 26.0 13.7 9.4 3.9 21.9 12.6 18.0 4.4 6.5 4.3 6.1 4.8 11.2 4.4 7.0 25.8 11.9 10.9 16.8 7.6 25.2 10.3 2.1 18.2 5.2 8.0 18.7 6.3 3.3 14.5 15.7 3.4 2.8 6.3 7.4 3.4 4.8 4.0 5.7 16.8 19.6 7.5 11.6 18.4 15.3 7.6 10.6 19.9 9.9 31.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell line enhanced" "Detected in many" "Daudi: 35.5;HMC-1: 36.0;Karpas-707: 33.4;U-698: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavourable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.1 2.2 3.3 1.2 14.7 5.6 3.7 7.6 11.4 8.3 8.7 6.6 1.1 35.5 7.0 4.3 2.2 1.4 3.2 10.2 6.2 3.8 3.3 2.8 0.6 4.4 13.4 36.0 7.1 3.2 10.3 5.4 3.4 2.6 33.4 20.6 1.7 17.4 30.4 1.9 5.1 2.9 20.3 10.7 4.9 7.5 1.2 1.3 1.9 1.9 1.6 1.3 7.0 4.1 8.1 4.0 5.8 4.2 13.7 22.2 38.7 6.1 4.6 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 4.8;REH: 4.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031510, HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA031510: AB_10603119, HPA031511: AB_2673915, HPA068559: " "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavourable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 6.4 8.2 3.8 4.3 6.5 2.9 4.0 9.9 6.3 5.7 6.6 5.5 4.2 2.2 6.0 5.5 5.3 3.5 5.3 3.6 5.0 3.5 3.9 6.6 4.1 2.5 4.3 7.5 5.7 12.4 4.7 4.6 6.3 4.0 6.2 2.7 5.6 2.9 6.7 6.1 6.8 2.6 5.9 3.7 7.0 6.3 7.9 4.2 2.6 4.7 4.1 3.8 4.4 4.2 2.1 2.7 0.4 3.8 0.9 1.1 0.5 0.0 0.3 0.0 1.1 2.9 1.7 0.0 2.3 0.3 0.5 1.1 0.0 1.9 1.5 0.6 1.2 2.0 0.0 0.6 0.9 4.8 0.9 3.6 0.9 0.2 1.4 3.7 0.0 1.5 0.1 0.8 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.6 0.0 4.4 2.4 1.1 0.0 0.0 1.0 0.9 0.3 0.6 0.2 1.7 0.0 0.0 0.0 1.1 1.1 0.0 0.1 2.3 0.1 1.9 0.6 0.1 0.0 3.8 0.1 0.6 1.4 0.7 2.1 0.9 0.1 2.7 1.0 1.1 0.5 0.4 0.9 1.4 1.5 0.1 0.5 3.8 6.5 9.9 6.3 5.0 3.5 4.3 7.5 4.0 4.2 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol 2800000 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavourable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favourable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 28.6 14.2 15.0 29.7 16.9 19.1 34.8 12.2 21.0 36.3 37.4 12.1 23.0 31.9 24.6 26.5 68.4 20.4 41.3 30.0 14.7 12.8 30.5 14.2 23.9 31.2 10.6 10.1 20.0 20.6 12.4 13.9 38.4 14.7 28.3 28.8 36.8 30.8 21.6 18.8 60.6 67.9 34.8 9.2 31.7 30.2 22.1 7.6 38.2 28.2 41.6 48.5 39.2 45.4 8.1 11.2 11.4 13.4 1.5 13.7 6.7 36.0 11.2 20.0 18.5 30.8 18.4 28.4 16.9 23.8 23.7 23.2 32.9 49.0 25.7 8.6 21.1 32.7 18.5 37.2 22.7 64.0 9.5 27.4 14.4 18.8 43.5 27.6 19.5 11.9 59.5 18.6 54.8 20.3 9.9 17.8 15.5 15.7 20.6 11.4 17.9 8.5 26.1 12.3 13.9 22.8 32.6 11.7 16.8 10.7 17.2 22.8 20.8 26.9 27.4 15.1 11.0 12.3 19.4 17.4 9.1 9.6 23.5 16.7 24.8 5.8 13.4 6.1 6.1 10.6 7.2 6.6 11.4 8.7 11.2 8.1 7.8 6.1 11.4 1.5 12.7 7.5 13.7 6.7 15.0 16.9 12.2 21.0 14.7 12.8 10.6 10.1 14.7 7.6 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492674-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 164.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 17.8 13.6 22.3 14.2 26.0 16.3 12.9 22.3 35.3 16.4 17.1 17.0 13.0 14.6 17.7 15.9 19.3 15.4 16.7 19.0 19.4 20.0 17.3 13.5 13.4 13.5 16.3 20.4 17.5 19.2 18.9 17.1 15.6 16.4 15.1 12.9 13.5 14.2 17.6 164.2 15.3 14.2 17.3 12.6 15.8 16.1 16.8 14.4 15.2 20.0 24.6 12.6 14.6 16.6 15.0 13.6 13.7 16.4 21.5 19.9 10.6 18.3 11.7 23.4 29.0 28.8 20.1 36.0 30.7 20.7 23.4 26.8 13.0 16.2 7.0 8.7 40.9 15.7 32.9 33.4 28.5 26.2 34.5 19.6 24.8 33.6 26.1 11.9 15.1 28.9 24.0 22.6 18.2 52.8 30.2 6.2 42.8 19.3 17.6 18.5 32.6 16.8 29.7 29.8 10.4 20.6 15.6 39.3 18.0 14.9 11.3 19.2 9.0 21.1 61.5 17.7 21.7 20.3 21.7 12.9 2.9 11.9 17.1 9.8 20.0 13.7 14.8 11.5 16.9 13.4 15.5 14.5 15.5 17.5 13.6 15.0 12.0 11.6 5.5 21.5 16.4 10.7 19.9 10.6 22.3 26.0 22.3 35.3 19.4 20.0 16.3 20.4 16.4 14.4 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023265-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: " "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavourable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 5.4 1.4 1.1 13.5 5.1 25.9 3.3 3.8 1.1 18.0 6.4 0.3 34.8 3.7 42.3 29.6 11.7 6.0 5.2 1.9 1.2 2.3 3.5 3.2 6.7 12.8 1.2 0.3 4.7 4.0 10.2 5.8 50.7 1.2 11.5 4.8 2.2 6.3 22.4 1.2 5.1 6.1 19.1 1.5 8.5 4.7 5.2 0.8 44.7 2.3 6.8 10.2 18.0 6.6 8.4 6.2 26.4 11.6 22.0 13.3 10.2 9.0 3.1 0.3 0.0 1.5 1.4 20.7 0.3 1.1 0.1 0.1 8.3 8.2 12.3 5.6 2.0 10.3 23.0 14.4 0.0 10.6 18.8 17.7 7.8 7.8 1.4 37.0 1.4 2.0 8.6 0.0 9.8 4.0 7.8 11.6 3.4 7.9 38.0 34.4 18.4 1.2 27.5 11.4 15.8 9.3 14.5 7.7 8.5 5.4 4.9 0.2 6.3 9.8 0.1 3.7 4.0 11.2 13.2 8.9 14.0 13.7 3.4 40.3 1.8 26.4 5.1 16.6 13.3 6.7 13.0 8.4 9.1 11.3 6.2 7.3 11.8 12.2 10.0 22.0 11.6 2.3 4.0 10.2 1.1 5.1 3.8 1.1 1.2 2.3 1.2 0.3 1.2 0.8 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98401403-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.3;granulocytes: 9.0;monocytes: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavourable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavourable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 16.5 16.6 6.5 8.1 12.4 2.5 20.5 2.6 10.6 17.2 13.1 10.5 14.2 4.6 22.2 13.1 9.0 16.0 12.6 10.0 7.4 4.1 14.7 12.0 16.2 10.8 12.8 3.6 22.8 10.7 15.1 18.9 53.1 9.9 15.0 6.0 8.2 10.8 16.4 11.6 10.0 10.8 23.5 12.9 8.2 9.5 10.1 11.4 3.4 10.6 7.9 5.9 16.4 24.3 1.9 8.3 9.0 8.7 1.8 1.8 2.9 37.6 7.1 7.5 9.9 24.4 12.2 7.5 13.1 11.8 12.3 10.7 5.2 16.0 0.0 11.4 13.0 15.3 5.2 11.3 19.9 9.0 6.7 10.1 3.5 3.5 8.3 3.3 8.8 8.1 19.5 6.3 17.2 5.2 4.2 5.5 8.9 4.7 8.4 4.0 2.2 2.8 7.4 6.5 3.2 14.0 4.7 1.9 4.4 8.3 9.6 8.1 7.9 5.5 3.9 8.3 5.3 12.5 7.2 4.4 6.5 2.7 7.4 4.2 13.1 2.1 8.6 4.5 1.3 8.7 1.4 1.9 0.8 1.8 8.3 1.3 1.1 0.7 9.0 1.8 5.4 3.4 0.1 2.9 6.5 12.4 2.6 10.6 7.4 4.1 12.8 3.6 9.9 11.4 STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710167-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 56.0" "Cell line enriched" "Detected in some" 8 "CACO-2: 19.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023194 Enhanced "HPA023194: AB_1857590" "unprognostic (4.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.42e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-6)" "unprognostic (7.83e-2)" "unprognostic (9.21e-3)" "unprognostic (1.46e-1)" "unprognostic (3.65e-1)" 0.1 0.0 0.1 0.1 0.7 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 56.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 19.7 2.4 0.0 2.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.1 0.2 0.0 0.1 0.1 0.1 0.1 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387852 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.7;brain: 21.1;retina: 31.9" "Group enriched" "Detected in some" 5 "RT4: 9.6;SK-MEL-30: 33.8" "Cancer enhanced" "Detected in many" "melanoma: 11.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040236 Uncertain Approved Centrosome Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 2.1 19.7 4.8 1.3 7.1 0.4 2.3 21.1 7.7 1.2 1.8 6.2 0.6 1.2 1.6 5.6 1.0 1.3 4.3 1.6 4.9 12.6 6.3 0.6 2.1 0.5 12.1 2.2 5.1 4.2 0.4 8.5 0.7 20.7 2.1 1.1 31.9 1.2 1.8 0.6 2.9 1.1 1.4 12.4 0.8 1.4 2.1 6.9 0.0 15.7 0.5 0.5 4.1 2.1 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.1 3.7 9.6 0.9 0.4 0.0 0.1 33.8 0.0 0.0 0.1 0.0 0.6 0.4 0.3 1.1 0.2 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 4.8 7.1 21.1 2.3 4.9 12.6 12.1 2.2 20.7 6.9 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051442-5500998 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.6;lymphoid tissue: 33.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 11.5;REH: 10.1;U-2197: 18.5;WM-115: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive B-cell: 1.3;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.3;dendritic cells: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA058536 Approved Vesicles,Microtubules Microtubules Vesicles "HPA058536: " "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favourable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 5.2 0.8 6.0 2.1 4.8 2.3 7.3 1.0 5.8 6.0 2.1 5.2 1.6 1.2 5.7 1.6 2.3 2.5 4.7 0.9 4.5 7.6 23.6 0.5 1.3 2.8 5.3 2.2 1.2 4.9 0.8 0.8 5.1 4.2 2.3 2.2 3.0 2.9 1.9 2.1 3.6 1.6 7.0 3.9 0.6 9.5 7.1 2.9 33.6 2.8 2.1 1.9 4.2 6.1 1.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.3 0.0 0.2 0.4 0.0 4.0 0.5 2.7 0.1 0.0 0.0 0.0 0.8 8.1 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 11.5 0.0 0.0 1.4 0.0 0.0 0.8 1.7 0.0 10.1 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 2.9 0.0 1.1 18.5 0.0 0.4 0.0 0.0 0.0 0.0 47.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.0 4.8 1.0 5.8 4.5 7.6 5.3 2.2 4.2 2.9 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017894 Uncertain "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavourable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavourable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 6.8 8.2 23.5 6.4 23.5 6.1 7.1 8.3 31.6 4.1 4.9 6.3 6.0 5.0 4.6 15.5 3.4 9.4 7.8 7.0 17.9 12.8 6.3 4.2 7.3 8.5 9.2 16.1 5.8 7.0 6.2 6.7 4.8 7.7 4.6 4.7 3.2 5.6 5.5 11.3 7.1 4.7 4.9 7.7 10.7 4.8 26.1 8.1 8.7 4.9 3.0 6.1 4.6 3.6 5.5 14.5 25.0 11.2 3.2 4.9 3.6 31.5 20.7 6.3 16.0 9.0 11.4 1.3 6.6 5.2 8.4 10.9 4.6 22.1 7.0 5.0 7.7 7.3 9.2 2.7 8.2 4.1 14.8 4.0 21.2 21.9 11.3 3.7 15.2 8.6 10.1 7.6 8.7 7.4 7.1 4.9 9.0 9.5 4.6 14.0 4.2 15.1 5.5 4.0 2.2 11.0 5.5 16.7 13.1 4.8 4.5 9.4 5.1 8.8 4.9 7.0 6.9 8.7 5.2 9.1 1.7 17.3 15.2 3.5 3.4 25.0 10.7 9.2 3.5 11.2 4.5 3.6 2.9 4.0 14.5 5.5 3.6 2.9 1.4 3.2 9.5 8.3 4.9 3.6 23.5 23.5 8.3 31.6 17.9 12.8 9.2 16.1 7.7 8.1 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell line enhanced" "Detected in many" "Daudi: 14.1;HEK 293: 12.0;Karpas-707: 13.2;SCLC-21H: 14.8;U-251 MG: 14.9;U-266/84: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: " "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favourable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.8 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.2 0.0 14.1 7.4 0.3 0.0 4.3 1.3 3.7 0.0 12.0 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 0.3 0.0 13.2 0.1 0.0 0.3 0.0 7.0 0.0 5.3 1.3 8.9 3.8 0.0 14.8 3.9 0.0 0.0 0.1 0.0 0.8 0.0 0.0 6.7 0.1 14.9 3.1 12.5 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101611-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 27.8;testis: 37.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA026452: , HPA051673: " "unprognostic (2.25e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (1.30e-2)" "unprognostic (3.25e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (9.46e-6)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-2)" "unprognostic (1.74e-1)" "unprognostic (4.67e-1)" "unprognostic (1.40e-1)" "unprognostic (4.99e-2)" 5.3 6.0 10.3 3.6 14.3 4.3 5.1 6.1 13.7 3.7 4.3 3.1 2.5 4.2 4.5 3.5 8.0 5.1 4.3 5.2 5.9 4.8 4.4 5.7 4.2 3.3 4.4 7.6 3.9 5.9 5.3 6.5 3.5 4.0 3.8 5.2 27.8 6.1 4.0 3.5 6.3 4.6 4.9 4.5 4.1 4.1 37.6 4.4 1.7 5.4 6.1 4.5 4.1 3.7 1.8 2.0 3.2 1.4 0.8 2.7 1.2 14.8 12.6 9.9 16.9 4.5 6.2 12.0 6.1 7.5 8.2 8.5 16.6 11.6 10.2 5.0 7.6 22.5 11.6 14.0 9.4 4.0 5.5 9.7 4.4 17.9 5.8 8.7 4.5 5.4 12.3 13.0 11.3 7.7 9.4 8.5 5.3 6.6 10.9 12.4 18.3 8.6 9.5 8.8 6.4 7.4 14.9 16.3 7.9 10.8 19.5 9.7 9.6 8.7 6.5 14.0 9.6 7.0 9.6 7.5 9.6 7.1 7.5 9.5 6.1 0.0 1.2 0.7 1.9 1.0 2.5 1.7 2.7 1.3 2.0 1.8 2.6 2.2 3.2 0.8 1.4 1.7 1.3 1.2 10.3 14.3 6.1 13.7 5.9 4.8 4.4 7.6 4.0 4.4 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672026-218702716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavourable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 4.8 10.0 7.5 4.7 11.4 2.0 6.4 7.9 11.1 9.1 7.4 7.0 11.9 4.1 14.4 13.3 5.0 13.9 9.8 3.3 6.3 3.5 10.1 4.4 6.9 3.9 2.3 6.6 13.6 9.7 12.3 23.2 3.9 7.6 9.5 6.3 9.3 7.3 8.3 3.3 4.6 5.8 7.8 5.5 4.9 7.9 63.2 4.2 3.5 11.4 3.7 5.0 9.3 7.1 1.8 1.6 3.2 1.9 2.2 1.6 1.7 2.7 6.4 14.0 11.9 15.2 11.9 8.5 7.6 6.1 9.7 9.2 8.3 4.6 3.7 10.6 7.9 5.6 9.5 7.9 8.6 1.6 7.9 3.6 19.1 11.4 7.4 5.0 6.1 12.8 5.9 9.5 6.8 7.2 8.3 4.7 8.0 6.4 3.0 6.3 8.4 4.1 5.6 6.0 3.7 11.9 14.0 11.4 9.7 5.9 9.6 3.9 9.8 4.1 6.9 13.5 5.0 5.1 5.2 6.0 4.6 1.9 8.4 2.4 5.6 0.0 1.9 3.2 1.5 1.2 0.9 1.8 1.1 1.3 1.6 0.6 1.1 1.6 0.2 2.2 1.4 1.3 1.0 1.7 7.5 11.4 7.9 11.1 6.3 3.5 2.3 6.6 7.6 4.2 STK38 NDR ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547470 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: " "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavourable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 19.1 8.4 12.4 39.8 10.0 19.4 32.8 18.8 12.7 16.0 26.3 7.8 14.9 17.0 18.8 16.4 28.1 14.6 18.3 15.3 12.1 7.0 15.0 17.3 21.7 45.9 11.9 6.4 12.3 9.5 7.8 11.0 15.4 9.0 17.0 27.1 11.3 24.8 18.7 14.9 21.8 29.1 28.1 13.1 25.1 16.4 24.4 11.0 34.3 10.6 13.4 28.5 22.4 19.8 10.6 13.1 33.2 30.5 25.8 27.6 22.4 17.6 13.0 13.8 14.8 27.9 21.3 12.0 19.7 16.0 20.5 20.7 10.0 12.1 23.7 15.3 29.3 18.9 11.4 8.2 24.3 9.7 9.8 17.0 16.9 9.0 13.8 6.4 9.4 14.0 21.6 15.9 10.2 12.8 13.8 13.9 29.2 10.6 10.3 16.7 5.7 11.6 40.2 16.7 6.3 19.4 22.2 16.1 7.6 24.0 11.1 13.8 11.8 16.9 12.3 16.7 14.8 13.3 12.7 11.7 20.7 16.7 3.8 25.0 16.0 33.2 19.8 15.0 27.6 22.6 21.5 10.6 22.9 24.1 13.1 8.1 20.5 22.3 27.1 25.8 30.5 6.6 21.4 22.4 12.4 10.0 18.8 12.7 12.1 7.0 11.9 6.4 9.0 11.0 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.3;granulocytes: 32.2;monocytes: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol Cytosol "HPA038623: AB_10967059, HPA051324: " "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 21.2 8.4 11.0 14.6 10.9 10.9 27.2 9.6 14.6 13.0 26.3 5.7 9.7 8.4 23.9 18.2 16.8 14.8 18.2 30.2 10.9 7.8 8.9 8.5 10.8 7.8 11.1 11.8 9.6 8.9 30.2 15.2 10.6 11.9 15.3 15.0 6.8 14.0 10.9 9.1 10.8 14.6 52.3 17.0 7.6 15.6 7.5 10.1 10.0 8.8 10.5 9.8 21.9 22.7 4.5 19.3 32.2 13.0 4.0 4.0 5.3 4.1 5.7 14.9 6.6 6.8 4.7 11.0 2.7 3.9 1.7 2.4 7.2 3.1 9.7 6.4 2.3 7.8 6.7 4.6 2.7 56.9 5.5 6.0 6.9 3.6 5.7 14.7 7.0 5.6 4.8 6.3 8.1 13.7 7.3 7.7 3.4 3.0 9.7 16.0 17.6 8.7 3.6 17.3 7.5 2.5 8.0 2.4 7.9 12.0 7.4 4.6 3.6 5.0 5.4 5.9 5.2 8.4 7.3 2.8 2.7 10.2 2.9 6.9 2.4 6.0 13.0 22.9 4.0 11.1 2.8 4.5 3.1 3.9 19.3 3.4 3.8 3.1 32.2 4.0 8.1 8.2 4.0 5.3 11.0 10.9 9.6 14.6 10.9 7.8 11.1 11.8 11.9 10.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168248141 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: , HPA062802: " "prognostic favourable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavourable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 6.2 2.1 8.4 4.6 11.0 1.3 3.5 9.3 14.1 4.3 9.1 8.3 1.7 10.5 2.3 4.7 14.1 1.9 5.9 7.6 9.8 7.4 2.9 0.8 2.4 7.3 12.3 9.7 3.2 9.9 5.0 8.2 1.2 14.2 9.9 11.7 7.1 22.8 3.8 2.2 3.4 6.1 4.3 19.0 2.5 11.2 35.5 5.5 7.2 2.2 1.8 8.0 5.6 5.3 0.7 1.0 0.0 0.7 1.9 3.4 0.5 6.6 4.0 15.2 4.8 9.4 13.8 1.5 16.7 12.3 11.2 10.4 0.0 21.6 18.3 4.6 10.8 17.3 9.7 12.2 14.1 5.8 6.0 7.6 4.4 13.5 17.4 10.2 0.8 9.5 17.3 13.3 13.9 7.6 0.1 0.0 23.4 3.8 17.7 3.6 10.5 8.5 25.4 6.0 1.5 8.4 16.5 22.5 9.5 5.8 0.8 6.8 3.0 7.5 7.1 13.6 4.2 9.6 10.9 0.0 0.0 14.7 10.3 9.1 9.1 0.0 0.7 0.0 2.5 0.4 1.3 0.7 1.9 3.4 1.0 0.7 0.4 2.0 0.0 1.9 0.3 0.3 3.3 0.5 8.4 11.0 9.3 14.1 9.8 7.4 12.3 9.7 14.2 5.5 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966474-45079959 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavourable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 9.5 8.8 10.4 24.5 11.5 39.5 8.1 7.5 13.4 7.8 8.6 10.3 5.4 8.1 9.3 6.5 8.9 7.3 9.4 6.1 9.3 8.8 6.3 7.4 18.8 30.6 10.5 9.1 8.3 6.4 5.9 9.3 8.2 7.7 7.5 10.6 7.4 9.3 8.7 4.2 11.4 16.1 8.2 12.0 29.1 9.6 7.4 9.6 32.3 8.0 4.9 36.6 11.5 8.7 10.8 6.9 40.6 13.3 10.3 14.5 7.9 11.6 7.9 10.1 7.2 6.2 7.8 7.0 10.3 15.8 17.5 15.9 22.4 6.4 28.6 9.0 7.3 12.4 10.7 13.8 22.5 12.8 5.7 20.8 11.6 15.7 10.9 26.7 29.6 6.3 11.4 16.4 17.9 6.4 9.6 16.5 8.8 9.2 19.9 18.1 6.2 5.4 12.9 11.2 13.3 6.4 8.0 4.8 5.9 15.3 8.9 11.7 8.1 16.9 8.2 13.2 12.9 15.2 11.9 21.6 16.9 31.8 12.9 12.8 9.7 24.4 7.6 20.5 14.5 7.7 14.4 10.3 13.8 13.3 6.9 10.8 14.3 11.9 40.6 10.3 13.3 3.9 13.3 7.9 10.4 11.5 7.5 13.4 9.3 8.8 10.5 9.1 7.7 9.6 STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favourable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" 29.4 43.7 52.2 20.1 43.2 19.3 40.5 39.1 53.3 25.1 24.8 18.1 27.6 24.1 19.7 34.9 35.2 31.1 25.5 45.2 43.2 38.6 24.0 25.9 23.6 28.1 42.0 42.5 29.4 43.4 39.8 27.2 12.1 35.0 23.4 17.7 18.6 37.7 29.7 92.5 33.7 20.9 24.5 34.5 19.7 22.8 13.8 25.4 13.1 29.1 30.2 19.4 22.3 35.9 18.0 21.0 19.4 14.5 10.3 16.9 6.9 17.8 24.2 16.4 27.7 37.5 34.4 9.4 24.4 28.7 29.0 25.8 30.1 22.8 18.1 17.3 40.8 15.3 20.2 36.7 12.1 19.9 66.8 11.2 35.0 25.1 54.1 18.9 22.4 40.8 39.4 33.9 21.5 29.3 18.1 30.3 44.8 70.7 20.5 18.6 18.3 26.5 31.7 10.7 44.5 38.7 17.9 28.6 23.2 19.5 43.0 30.6 27.4 36.3 23.2 26.6 23.3 22.0 29.3 30.0 31.0 29.2 21.0 17.2 30.0 11.9 14.5 19.4 16.9 11.9 15.4 18.0 14.6 14.7 11.7 17.3 13.6 12.9 14.0 10.3 12.4 21.0 12.2 6.9 52.2 43.2 39.1 53.3 43.2 38.6 42.0 42.5 35.0 25.4 STYXL1 "DUSP24, MK-STYX" ENSG00000127952 "Serine/threonine/tyrosine interacting like 1" Q9Y6J8 7 75996338-76048004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050261 Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA050261: " "unprognostic (6.24e-2)" "unprognostic (1.12e-1)" "unprognostic (7.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.88e-3)" "unprognostic (9.33e-2)" "unprognostic (1.50e-3)" "unprognostic (4.77e-2)" "unprognostic (8.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.47e-3)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (3.17e-2)" "unprognostic (2.28e-1)" "prognostic favourable (8.22e-4)" 9.4 19.2 16.0 10.2 23.1 12.7 17.5 12.8 19.8 15.7 15.1 19.6 13.9 10.5 10.3 21.0 21.1 28.2 9.4 13.2 16.6 12.1 14.8 20.1 11.3 13.7 20.9 13.5 15.4 30.0 15.9 19.9 24.6 16.8 16.6 20.1 12.2 16.0 13.9 12.4 19.3 10.3 14.0 17.0 17.4 14.0 25.0 19.7 20.8 19.9 12.1 19.5 14.8 14.6 19.7 23.0 30.8 29.3 24.7 22.1 17.4 19.7 10.6 8.3 11.1 13.2 14.4 8.7 8.9 12.7 14.5 14.4 12.2 18.0 4.6 4.5 11.8 8.8 13.5 17.9 21.1 14.7 5.9 5.6 5.0 10.9 18.8 7.8 10.3 14.0 21.0 17.4 43.7 14.1 18.1 13.9 12.9 16.0 3.0 33.4 7.0 25.6 11.9 7.0 12.2 18.4 12.9 11.0 11.4 8.3 19.2 22.3 21.1 15.1 7.0 12.5 5.3 13.7 12.6 15.1 9.6 15.7 11.1 14.9 19.4 30.8 29.3 25.8 13.7 25.3 15.2 19.7 13.2 15.2 23.0 15.6 11.7 13.2 24.6 24.7 23.7 15.1 22.1 17.4 16.0 23.1 12.8 19.8 16.6 12.1 20.9 13.5 16.8 19.7 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134533 "Enzymes, Predicted membrane proteins" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favourable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 13.8 20.8 11.0 33.0 15.3 13.8 14.9 13.3 19.3 15.1 14.2 21.0 20.2 13.2 16.0 21.1 14.4 16.1 15.3 12.9 11.3 10.0 16.4 78.0 14.2 28.9 18.2 8.7 17.1 68.1 24.4 21.0 20.9 14.4 15.0 15.4 13.3 48.9 22.6 16.7 14.4 19.6 13.6 12.8 27.1 18.3 14.4 14.9 10.3 23.5 8.0 42.2 13.3 12.6 17.5 13.0 11.6 5.4 2.2 5.5 3.8 8.5 10.9 6.6 8.9 16.8 9.6 6.5 8.8 9.1 11.3 8.0 5.9 14.9 48.0 12.1 11.3 13.2 7.1 8.9 9.4 7.4 5.4 7.5 12.7 13.2 20.4 11.3 13.7 12.2 16.2 9.9 22.5 7.3 9.4 24.6 6.6 12.6 4.9 8.2 7.1 7.6 8.4 5.5 19.3 7.1 8.4 4.3 8.8 8.2 20.3 14.2 15.1 7.4 6.9 7.9 5.2 14.0 5.9 49.2 34.0 55.5 10.6 5.8 8.8 11.6 5.4 9.3 5.5 3.3 5.0 15.4 3.9 5.1 3.1 17.5 2.9 3.0 5.2 2.2 3.2 13.0 3.6 3.8 11.0 15.3 13.3 19.3 11.3 10.0 18.2 8.7 14.4 14.9 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366239-71532374 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001075, CAB016283" Supported Enhanced Nucleoplasm Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favourable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 20.1 16.2 15.0 17.1 19.8 16.3 17.7 20.7 18.0 20.7 15.5 23.8 17.1 10.0 25.4 17.1 14.4 19.1 16.1 12.9 15.4 12.0 11.9 12.9 13.8 17.8 18.5 16.5 23.9 17.5 25.5 19.3 15.4 17.3 16.9 15.4 20.8 14.5 16.1 19.6 16.8 17.1 18.3 17.2 21.3 15.8 12.2 21.3 19.4 20.1 12.0 18.7 18.4 15.8 5.0 4.7 5.2 4.8 4.2 4.9 1.8 11.2 9.8 11.2 7.5 9.0 15.6 7.0 8.4 7.8 8.9 7.4 7.3 6.8 10.5 7.2 9.4 10.7 15.6 6.7 11.4 6.9 13.7 12.5 12.9 7.2 6.5 23.7 12.1 9.1 6.8 9.5 18.0 9.2 17.0 25.5 9.0 7.9 13.1 10.5 12.9 12.9 12.1 22.8 12.8 6.0 14.6 5.9 9.2 23.4 8.2 10.4 6.0 12.6 11.6 10.5 8.8 8.4 5.8 10.9 10.1 13.6 5.8 19.1 7.8 4.4 4.1 1.1 4.4 2.8 3.8 3.0 4.6 4.5 4.7 5.0 4.4 4.9 5.2 4.2 4.8 3.5 3.1 1.8 15.0 19.8 20.7 18.0 15.4 12.0 18.5 16.5 17.3 21.3 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390464-29551904 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Approved Vesicles 13000 Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 17.2 11.5 19.1 11.9 25.0 12.7 13.3 20.1 24.4 15.8 11.9 22.2 7.9 7.1 14.9 10.8 12.7 11.0 11.6 15.3 18.7 15.5 13.6 10.6 13.2 11.1 30.0 17.6 13.5 9.3 31.7 13.7 14.3 21.8 12.0 10.7 10.9 11.1 13.3 15.0 13.8 9.8 17.7 21.0 13.0 10.8 14.3 23.5 11.7 17.7 6.0 11.2 14.5 17.1 2.4 4.8 5.5 2.1 1.4 3.0 0.9 13.6 24.3 19.2 8.2 14.3 18.1 8.1 12.9 13.8 11.9 12.5 13.1 4.8 8.5 12.7 21.0 10.7 17.5 8.9 21.4 17.6 12.9 13.5 14.1 7.0 10.4 14.9 12.5 11.9 11.5 17.5 18.0 16.2 13.8 7.7 15.5 9.1 11.7 5.5 8.1 6.2 10.9 27.1 5.9 11.2 19.7 10.6 13.0 22.2 20.8 13.4 15.0 13.8 23.5 18.2 14.8 15.9 18.0 7.1 15.3 9.8 13.3 9.4 16.4 1.7 1.9 1.5 2.0 2.1 1.6 1.6 2.0 2.4 1.7 2.4 3.0 2.2 5.5 1.4 1.9 4.8 1.2 0.9 19.1 25.0 20.1 22.7 18.7 15.5 30.0 17.6 21.8 23.5 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973641-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.51e-4)" "prognostic favourable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favourable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favourable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 27.8 24.1 26.2 15.1 26.7 12.3 17.7 29.2 30.6 13.5 13.6 21.5 11.8 18.5 16.8 13.0 12.4 14.1 15.1 17.6 25.0 18.2 13.9 10.4 23.0 14.4 22.1 22.7 15.8 16.3 26.2 18.7 22.5 20.7 13.6 9.6 15.0 17.1 15.9 22.8 20.0 19.3 14.8 14.9 26.3 16.0 21.2 20.2 14.0 15.9 9.8 11.5 12.8 18.0 2.6 3.3 4.8 2.8 2.0 3.2 2.0 11.2 21.5 11.8 18.5 13.8 9.3 18.1 20.6 11.0 14.0 13.1 17.2 15.0 12.2 17.5 14.8 17.5 10.7 10.4 7.5 18.9 22.7 13.1 21.7 17.2 10.1 12.8 25.2 10.9 9.0 14.8 6.0 23.3 11.7 12.4 13.3 20.7 14.9 18.3 11.4 14.5 27.7 17.1 11.3 8.8 10.6 13.9 11.1 11.8 15.8 6.1 19.8 14.6 32.5 24.1 11.2 17.1 11.9 18.1 11.6 11.5 14.8 14.8 17.5 1.3 2.8 1.5 2.9 2.7 3.1 2.0 2.9 2.6 1.8 2.6 1.6 1.4 4.8 2.0 1.4 3.3 3.2 2.0 26.2 26.7 29.2 30.6 25.0 18.2 22.1 22.7 20.7 20.2 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372945 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 14.6 16.2 31.9 24.1 31.0 30.8 14.6 44.3 33.5 11.6 21.2 17.2 10.3 23.1 15.2 11.4 16.0 9.8 16.9 15.1 27.8 31.7 14.0 15.3 19.4 26.3 25.7 20.8 17.5 10.9 20.2 23.6 11.9 20.7 25.6 21.3 12.0 13.6 14.6 18.5 17.0 31.6 15.3 23.7 24.2 20.9 8.9 28.6 28.3 18.1 9.9 26.9 18.5 18.3 20.9 22.4 38.2 37.8 36.4 27.8 17.1 8.2 5.7 4.3 3.7 10.5 12.8 4.9 8.6 9.8 5.0 6.6 2.9 12.8 25.2 2.8 11.5 7.4 3.7 7.7 7.9 9.1 3.2 29.7 2.9 3.7 12.3 30.4 41.9 8.7 9.3 15.9 23.3 16.1 17.2 3.0 9.2 5.8 16.0 20.0 1.6 3.0 9.4 5.8 2.6 4.7 14.3 0.8 4.2 8.0 3.6 11.0 7.4 22.8 24.9 8.7 1.5 8.1 7.4 2.9 2.8 19.9 12.3 21.0 11.6 38.2 17.0 37.6 27.8 23.3 26.2 20.9 21.2 24.1 22.4 19.3 18.8 24.5 37.7 36.4 37.8 20.9 19.3 17.1 31.9 31.0 44.3 33.5 27.8 31.7 25.7 20.8 20.7 28.6 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64451880-64502108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease mutation, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA045797: , HPA060211: " "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavourable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavourable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 19.1 23.3 13.7 16.8 17.1 32.3 19.1 17.8 20.5 14.9 18.3 10.0 14.1 18.0 17.0 15.1 15.3 13.8 15.6 11.7 14.7 15.6 15.4 20.8 17.8 18.3 20.2 13.6 15.6 11.1 13.1 27.2 40.6 21.1 16.3 12.9 10.1 15.0 18.3 24.8 12.1 21.4 17.2 18.8 24.6 14.5 27.9 16.9 3.4 13.3 12.6 16.7 18.4 19.6 9.7 8.2 22.5 11.9 16.3 11.8 5.9 13.4 15.5 8.8 12.9 15.8 16.0 19.5 14.8 21.5 13.9 13.3 8.7 8.2 18.9 12.9 16.0 12.7 11.4 12.4 16.5 17.3 10.8 20.2 11.2 12.0 17.4 20.6 25.3 12.0 11.4 13.9 13.4 18.5 15.5 27.5 17.9 16.5 0.6 16.2 17.7 9.1 9.6 9.8 18.2 15.2 24.5 7.4 10.7 19.5 20.0 14.3 20.5 15.0 17.1 12.6 12.2 10.1 14.4 17.4 30.3 18.4 15.9 11.4 16.2 22.5 7.3 16.6 11.0 11.9 11.8 9.7 8.0 11.0 8.2 7.6 2.8 7.1 15.1 16.3 10.6 1.9 9.5 5.9 13.7 17.1 17.8 20.5 14.7 15.6 20.2 13.6 21.1 16.9 TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463295-9741037 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.3" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "CAB005363: AB_2240272, HPA067703: " "prognostic unfavourable (8.50e-4)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (2.89e-2)" "unprognostic (2.44e-1)" "unprognostic (1.40e-2)" "unprognostic (2.21e-3)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (3.27e-1)" "prognostic favourable (1.32e-4)" "unprognostic (2.66e-1)" "prognostic favourable (4.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.38e-2)" "unprognostic (3.40e-3)" "unprognostic (1.53e-1)" 6.5 7.1 10.1 6.0 12.3 4.5 8.1 3.3 8.1 21.4 7.9 13.2 18.0 2.1 33.0 26.4 8.3 12.4 6.7 5.2 8.6 9.0 12.5 11.0 5.2 9.5 7.6 6.0 13.8 11.3 21.0 24.3 14.5 7.5 24.7 4.1 9.8 5.5 33.0 4.9 5.8 4.2 22.4 9.0 5.7 7.0 9.9 8.5 14.7 9.4 3.4 7.1 15.3 24.5 3.2 3.1 17.3 4.2 0.3 3.1 1.7 0.0 13.5 8.6 23.0 8.0 8.4 8.5 5.2 11.6 10.0 10.5 10.1 9.3 14.4 0.3 10.3 3.1 18.8 4.1 14.7 5.9 9.3 9.0 16.5 11.9 11.4 3.2 32.5 7.5 4.7 10.4 5.5 9.2 15.8 25.1 5.7 11.4 7.8 12.2 17.1 14.6 17.6 6.8 17.6 13.6 7.7 11.1 5.0 12.5 3.1 7.5 6.1 7.1 13.3 3.5 8.7 0.3 2.0 15.3 11.9 11.4 12.9 7.9 3.3 4.4 4.2 4.9 2.1 2.6 1.7 2.0 1.6 1.9 3.1 3.2 3.1 2.8 17.3 0.3 1.7 0.3 2.5 1.7 10.1 12.3 3.3 8.1 8.6 9.0 7.6 6.0 7.5 8.5 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "Transducin beta like 1 X-linked receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favourable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 20.7 26.0 27.4 24.3 26.8 27.3 20.3 27.5 28.1 28.9 29.9 22.6 15.4 24.0 23.9 20.5 23.8 21.9 22.7 30.3 26.2 20.7 19.9 21.8 30.8 27.8 21.4 25.9 26.5 19.9 30.6 11.3 24.0 19.7 24.4 23.2 24.7 21.3 17.7 21.1 17.8 24.3 21.9 19.6 24.7 21.3 17.4 22.3 28.4 45.6 14.9 32.1 29.1 25.5 7.4 13.3 12.9 4.6 6.8 8.3 4.1 23.4 12.0 15.6 8.8 13.3 14.5 9.3 7.4 11.5 6.4 8.9 13.8 19.4 24.0 35.1 10.6 14.5 11.7 15.5 13.0 25.2 3.7 13.5 20.6 8.2 11.4 21.4 8.0 21.3 8.0 9.5 23.6 10.0 10.1 42.6 8.3 8.4 20.0 2.9 9.9 8.2 11.5 19.9 25.6 5.8 33.2 5.6 9.0 10.0 7.9 9.3 28.6 16.4 15.3 10.6 8.9 5.9 16.0 23.3 29.8 69.5 7.1 16.0 12.0 11.4 3.0 3.8 5.8 4.6 5.1 7.3 5.7 6.6 4.0 7.4 5.0 6.4 12.9 6.8 3.9 13.3 8.3 4.1 27.4 26.8 27.5 28.1 26.2 20.7 21.4 25.9 19.7 22.3 TESK1 ENSG00000107140 "Testis-specific kinase 1" Q15569 9 35605305-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 30.9 19.4 13.5 10.8 20.5 5.6 25.4 13.4 26.4 14.3 15.2 15.0 9.7 13.7 15.3 13.4 11.0 12.0 13.0 12.8 13.7 13.1 10.5 10.0 11.5 10.7 14.1 10.3 17.0 16.0 13.1 15.7 12.3 12.6 15.1 8.8 14.2 14.6 21.0 47.2 13.7 12.7 16.9 7.3 11.0 12.9 28.4 12.9 9.2 13.0 12.3 9.0 16.6 20.9 1.0 2.3 0.3 1.8 2.1 4.9 1.5 9.9 9.3 6.4 10.6 25.7 10.7 7.3 11.4 10.2 10.6 6.8 5.4 2.8 18.1 6.5 11.4 3.4 4.0 8.2 2.0 11.6 5.4 2.6 8.8 4.7 15.0 2.2 8.7 10.4 13.0 8.3 11.4 7.4 3.0 6.5 10.5 11.0 5.0 11.0 3.9 10.9 7.8 3.9 4.2 7.8 4.6 5.2 6.4 6.5 7.9 4.8 9.4 3.3 6.4 23.6 10.1 16.9 6.8 4.0 5.6 6.7 17.1 2.6 5.3 0.0 1.8 0.3 3.4 0.4 3.0 0.8 1.4 4.9 2.1 1.0 1.5 1.6 0.0 2.1 0.8 2.3 0.3 1.5 13.5 20.5 13.4 26.4 13.7 13.1 14.1 10.3 12.6 12.9 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.0;RT4: 12.7;SK-MEL-30: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027257: AB_10602477, HPA063869: " "unprognostic (2.95e-1)" "prognostic favourable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.0 0.6 4.3 1.9 3.2 3.6 1.5 5.2 0.6 1.5 2.0 3.4 2.7 1.5 3.7 4.3 3.5 1.8 2.7 1.7 1.2 9.8 1.8 2.9 2.1 3.0 1.5 0.6 10.9 1.2 0.6 3.0 2.4 3.4 1.5 4.4 0.1 1.4 1.7 12.7 0.3 1.4 3.3 6.4 12.1 9.9 1.5 0.0 0.2 2.0 1.6 1.1 7.1 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: " "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 11.1 6.9 10.3 11.5 14.6 20.0 15.4 12.6 11.3 14.4 20.0 11.0 5.5 7.4 18.8 8.0 13.2 10.9 14.9 9.7 7.8 7.5 16.0 9.8 19.2 18.9 15.8 4.3 13.3 8.8 6.5 13.5 50.9 14.1 12.3 9.2 10.4 10.2 12.2 8.4 6.6 11.0 28.6 17.9 13.9 25.5 11.4 12.4 10.8 7.7 8.1 11.5 13.0 10.2 1.6 2.0 13.1 2.4 4.0 8.3 1.9 3.3 5.0 30.8 9.5 7.2 5.3 4.6 11.5 12.6 10.7 12.1 5.1 2.4 7.5 3.6 9.0 8.0 10.4 8.9 14.6 19.5 3.2 11.2 5.6 4.5 11.9 6.9 27.3 11.0 9.6 16.8 7.9 1.9 15.5 3.2 14.7 5.2 1.0 7.8 6.5 3.0 2.8 67.2 3.2 2.6 0.8 8.3 9.7 8.9 39.9 11.9 7.4 9.4 3.5 8.0 6.9 34.3 7.0 3.2 3.2 5.1 16.8 11.9 6.9 13.1 2.4 9.1 8.3 1.6 7.2 1.6 3.6 6.1 2.0 1.3 3.5 6.7 4.9 4.0 1.9 1.4 2.2 1.9 10.3 14.6 12.6 11.3 7.8 7.5 15.8 4.3 14.1 12.4 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.4 14.4 0.9 0.0 53.4 80.5 2.4 12.5 17.6 4.3 4.3 3.2 13.3 0.3 45.3 16.8 5.0 0.6 18.3 7.2 1.0 1.3 1.4 1.6 16.2 22.8 2.2 11.8 69.5 16.3 18.6 18.0 46.7 0.2 0.0 65.8 0.2 2.3 1.6 0.4 5.8 2.0 5.8 0.3 23.2 5.8 0.0 0.9 3.7 1.0 3.5 0.0 2.4 60.3 21.2 5.2 9.6 4.7 0.4 0.0 2.0 12.7 2.5 8.5 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 106.0;lymphoid tissue: 70.0;tongue: 86.8" "Cell line enhanced" "Detected in many" "BEWO: 12.8;HaCaT: 17.6;HeLa: 11.5;MCF7: 12.6;SK-BR-3: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 78.3" "Region enriched" "Detected in single" 11 "cerebellum: 3.0" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171" Enhanced 430000 "CAB015159: AB_2202870, HPA040171: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 2.9 0.2 0.2 0.4 0.2 0.2 0.7 3.0 0.3 10.1 1.0 0.2 0.2 0.3 0.5 2.0 106.0 1.3 0.2 0.6 0.2 0.0 0.6 0.3 0.9 0.4 0.2 0.2 0.7 1.3 0.2 0.2 0.9 0.2 0.5 0.3 0.4 12.8 1.4 0.7 9.3 0.3 0.2 0.2 0.4 0.2 0.4 0.2 0.5 0.4 86.8 70.0 0.4 17.2 0.4 0.5 0.0 0.5 0.0 1.1 0.2 0.8 1.5 0.8 0.7 0.0 0.6 12.8 0.3 0.2 0.7 1.2 0.9 1.3 0.7 1.7 0.9 17.6 2.1 1.4 0.5 1.4 2.4 1.0 11.5 4.0 0.6 0.6 1.1 1.1 7.0 0.4 1.5 0.5 0.7 0.7 0.5 12.6 0.5 1.3 0.2 1.6 0.8 0.1 0.8 0.5 1.5 0.9 1.1 0.2 15.7 0.0 1.1 0.8 0.6 0.8 3.7 1.5 0.6 1.1 1.2 0.2 0.3 1.5 0.9 0.0 0.5 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.2 0.2 3.0 0.2 0.2 0.0 0.2 0.2 0.2 0.2 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127387-38166578 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 187.6;placenta: 212.7" "Group enriched" "Detected in many" 4 "CAPAN-2: 160.1;EFO-21: 53.8;HUVEC TERT2: 72.7;TIME: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 2.5;memory B-cell: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 23 "B-cells: 1.9;dendritic cells: 2.4;monocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" 1700000 Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavourable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavourable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 33.3 9.5 6.0 18.3 8.1 1.0 7.7 4.3 7.5 94.3 12.6 4.0 4.7 8.4 54.6 21.7 15.8 58.7 62.8 77.1 7.5 3.4 25.3 187.6 61.2 16.4 6.9 3.0 18.7 5.0 5.2 25.6 212.7 8.5 33.6 6.3 57.4 1.9 17.1 19.3 0.7 12.8 43.9 5.7 20.4 13.6 7.4 6.4 0.8 17.0 3.4 3.1 38.2 21.6 1.9 2.4 0.0 2.5 0.0 0.0 0.2 6.5 4.9 0.0 0.1 5.1 0.5 2.5 9.9 4.8 0.0 0.1 8.0 160.1 0.0 53.8 0.1 0.1 0.0 23.2 0.3 0.0 0.0 1.0 0.2 3.5 20.9 0.0 0.0 0.5 0.0 4.2 0.0 72.7 2.1 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 7.2 0.0 0.0 0.1 23.2 0.0 0.8 0.2 0.0 94.8 0.1 6.0 0.7 4.7 0.0 0.0 0.0 6.5 0.0 1.9 0.0 0.2 0.0 0.0 2.5 0.0 1.9 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 8.1 4.3 7.5 7.5 3.4 6.9 3.0 8.5 6.4 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341078 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 195.0;lymphoid tissue: 152.6;tongue: 206.5" "Cell line enriched" "Detected in some" 6 "EFO-21: 11.6" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 205 "neutrophil: 20.4" "Lineage enriched" "Detected in single" 205 "granulocytes: 20.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA004728 Enhanced 14000000 "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.1 0.1 195.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 24.5 0.0 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 206.5 152.6 0.0 2.8 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "prostate: 107.8" "Cell line enhanced" "Detected in some" "BEWO: 9.5;hTERT-HME1: 2.6;NB-4: 5.1;RPMI-8226: 3.6;SH-SY5Y: 2.8" "Cancer enriched" "Detected in single" 312 "prostate cancer: 75.4" "Region enriched" "Detected in single" 254 "cerebral cortex: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA032072, CAB033571" Enhanced "CAB033571: AB_2287329, HPA032072: AB_10603350" "unprognostic (4.40e-2)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.65e-1)" "unprognostic (8.56e-3)" "unprognostic (5.08e-2)" "unprognostic (1.44e-8)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.68e-1)" "unprognostic (6.41e-2)" 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 25.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.1 2.6 0.3 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.7 0.7 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 TGM5 TGX ENSG00000104055 "Transglutaminase 5" O43548 15 43232595-43266857 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 9.7;lymphoid tissue: 10.4;skin 1: 24.3;tongue: 13.1" "Cell line enriched" "Detected in some" 7 "HEL: 19.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "cerebellum: 2.9" "Not detected" "Not detected" "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.3 0.0 0.1 0.1 0.1 0.2 2.1 0.1 0.1 2.6 0.1 0.1 0.1 0.0 0.7 0.1 9.7 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.6 0.0 0.1 2.8 3.4 0.1 24.3 0.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 13.1 10.4 0.8 4.7 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.4 0.0 0.7 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TGM6 "dJ734P14.3, SCA35, TGM3L, TGY" ENSG00000166948 "Transglutaminase 6" O95932 20 2380908-2432753 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "lymphoid tissue: 5.7;skin 1: 3.3;tongue: 4.2" "Cell line enriched" "Detected in single" 12 "SCLC-21H: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 34 "cerebellum: 1.8" HPA059196 Uncertain "HPA059196: " "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.2 5.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276280-43302255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.9;testis: 2.9" "Cell line enriched" "Detected in single" 78 "EFO-21: 8.9" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 5.9 0.0 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 TGS1 "NCOA6IP, PIMT" ENSG00000137574 "Trimethylguanosine synthase 1" Q96RS0 8 55773142-55825448 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025024, HPA029824" Supported Supported Cytosol Cytosol "HPA025024: AB_1854330, HPA029824: " "unprognostic (4.13e-2)" "unprognostic (7.46e-2)" "unprognostic (6.64e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.94e-2)" "unprognostic (9.32e-2)" "unprognostic (3.15e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.62e-2)" "unprognostic (7.23e-2)" "unprognostic (3.42e-1)" "unprognostic (2.85e-2)" 12.1 10.0 7.2 18.2 9.1 13.3 12.6 18.1 10.2 11.6 14.1 7.2 18.2 7.6 14.3 16.0 13.5 14.1 9.4 8.5 8.8 6.7 12.6 8.8 10.7 18.8 5.3 6.9 14.8 9.6 12.3 13.8 10.2 7.4 11.9 10.1 7.1 11.6 20.0 19.6 14.1 16.8 11.5 6.3 17.7 10.5 10.8 8.0 29.7 11.6 13.2 18.3 14.5 14.5 10.4 10.1 10.0 7.6 6.3 13.1 4.8 9.1 6.9 8.2 9.1 7.2 7.2 8.6 8.6 8.8 9.2 9.4 6.4 8.9 20.8 6.0 5.7 8.8 17.3 11.0 11.7 11.6 6.6 22.2 7.7 3.6 10.2 12.4 7.7 7.1 7.5 8.8 18.1 7.0 18.1 8.2 7.5 7.0 27.9 8.1 30.0 2.8 19.9 5.9 6.6 8.4 9.2 8.4 11.5 11.0 6.7 9.9 9.2 7.6 6.9 6.8 8.6 8.1 7.8 7.2 4.7 26.3 6.7 9.7 8.6 10.0 5.5 8.8 11.6 6.3 13.1 9.8 11.6 11.2 5.5 10.4 11.9 12.4 6.3 6.3 7.6 10.1 9.2 4.8 7.2 9.1 18.1 10.2 8.8 6.7 5.3 6.9 7.4 8.0 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785460-2815807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol 1400000 Cytosol "CAB025497: , HPA035262: " "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favourable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 8.2 9.4 19.1 12.3 19.8 18.4 6.2 21.7 26.1 5.2 11.8 14.1 5.8 24.6 7.5 8.4 11.0 8.4 6.7 11.6 18.5 15.4 7.1 30.4 6.2 11.9 14.1 15.2 11.1 7.8 7.0 12.7 22.3 13.1 18.1 8.2 11.9 13.7 6.8 29.1 11.9 20.0 7.1 10.7 9.8 7.8 27.3 10.9 17.0 7.5 11.5 11.3 5.8 6.8 7.5 9.8 8.0 7.5 3.9 9.5 3.2 29.2 21.8 8.5 18.2 4.4 4.3 30.4 18.3 6.8 18.2 14.8 25.6 9.4 26.4 9.0 7.1 23.8 12.6 15.0 7.7 0.1 26.5 9.3 24.0 30.2 4.7 18.0 14.6 4.8 5.4 15.1 6.8 10.3 21.7 12.9 7.7 22.7 20.0 33.8 25.1 30.1 16.7 11.3 25.0 7.6 17.0 23.1 18.5 16.0 14.4 8.9 14.0 17.5 11.7 14.0 12.1 29.8 30.9 22.7 19.0 17.8 15.6 30.3 16.6 8.0 3.5 1.6 5.5 3.9 4.5 5.6 4.0 7.4 4.9 7.5 5.1 4.3 1.7 3.9 7.5 9.8 9.5 3.2 19.1 19.8 21.7 26.1 18.5 15.4 14.1 15.2 13.1 10.9 TIPARP "DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 24.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules Microtubules "HPA036796: AB_10672268" "prognostic favourable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 31.6 29.8 10.9 11.1 24.7 31.8 19.9 7.1 16.3 16.2 12.7 14.2 18.8 6.8 18.3 20.7 27.2 27.8 18.8 26.5 16.0 9.4 14.2 21.3 20.2 15.2 16.2 6.2 37.0 14.5 73.8 11.4 6.1 30.9 13.6 7.5 10.0 8.2 36.0 17.4 26.2 22.1 21.6 37.4 8.4 11.3 23.1 12.5 8.4 10.8 19.1 13.8 18.7 16.7 3.7 3.3 24.1 5.4 7.0 6.0 2.2 12.5 8.8 3.0 2.5 11.1 8.1 2.4 20.9 17.0 10.7 14.9 5.0 26.1 3.7 6.8 23.7 13.0 7.5 50.2 15.9 7.9 5.6 6.3 9.2 3.4 4.7 2.1 11.6 6.6 31.5 10.8 26.2 9.7 4.9 15.1 37.0 2.4 1.8 2.8 3.4 7.4 3.0 6.8 12.8 11.2 5.9 9.2 2.3 16.4 5.1 3.5 7.9 3.7 20.9 4.6 1.5 8.6 7.5 16.9 3.0 3.3 7.9 3.3 15.5 24.1 3.5 4.7 4.2 2.2 6.0 1.9 4.2 5.6 2.3 3.7 2.6 3.5 10.7 7.0 5.4 3.3 4.7 2.2 10.9 24.7 7.1 16.3 16.0 9.4 16.2 6.2 30.9 12.5 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 13.8 20.1 22.0 32.9 21.0 14.4 26.2 18.3 23.2 19.6 20.2 8.4 22.3 13.7 16.1 16.1 14.1 14.4 16.2 12.7 20.6 19.3 19.5 21.4 22.1 33.7 21.7 20.8 21.5 19.8 37.8 21.0 36.0 18.3 18.0 18.2 10.8 16.4 30.3 18.6 15.4 18.9 20.5 18.7 26.0 19.9 24.2 12.2 28.0 25.7 11.1 21.7 21.9 19.1 10.5 5.3 11.3 5.5 9.5 12.3 6.6 8.5 8.3 12.1 9.4 8.6 8.7 13.4 11.8 17.3 12.0 10.1 11.5 13.9 17.7 9.7 17.8 7.3 15.3 13.2 13.2 21.0 7.7 20.5 10.4 14.9 9.3 25.9 10.4 9.4 13.5 23.8 15.7 13.1 21.0 15.1 7.2 10.6 21.7 8.3 11.1 4.7 16.4 14.7 18.2 9.9 16.5 13.8 10.7 12.9 9.2 8.8 7.5 9.1 17.8 10.7 13.1 7.0 9.2 12.7 21.3 32.1 13.3 10.7 10.8 11.3 3.9 6.5 6.6 3.0 9.1 10.5 10.7 7.2 3.5 10.5 12.3 8.1 5.0 9.5 5.5 5.3 10.0 6.6 22.0 21.0 18.3 23.2 20.6 19.3 21.7 20.8 18.3 12.2 TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-2)" "unprognostic (9.53e-3)" "unprognostic (6.57e-2)" "prognostic unfavourable (9.40e-4)" "unprognostic (4.53e-2)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (4.78e-2)" "unprognostic (5.32e-2)" "unprognostic (9.79e-2)" "unprognostic (4.32e-2)" "unprognostic (4.88e-1)" "unprognostic (7.30e-2)" 7.4 6.4 8.3 7.3 7.2 12.0 12.5 7.8 14.0 5.8 7.8 4.0 3.1 7.4 9.0 3.1 9.0 6.2 9.9 17.8 7.7 7.4 5.7 5.0 6.9 8.7 7.7 7.3 8.5 8.9 5.6 6.9 9.0 10.4 6.6 5.3 7.5 8.6 8.7 11.7 8.7 10.1 6.5 8.6 8.9 6.7 47.9 5.7 4.1 11.7 3.1 10.0 8.5 7.2 4.6 3.6 8.6 2.8 6.6 4.9 1.5 15.5 14.3 24.8 26.2 8.1 10.5 14.4 17.2 13.4 20.4 18.7 14.9 14.0 30.5 8.8 11.2 10.6 17.5 7.3 19.5 16.1 13.9 20.7 13.5 15.0 14.5 21.8 13.2 9.0 10.0 13.7 16.6 10.1 20.5 13.9 10.9 33.9 31.1 7.8 15.7 12.0 21.3 32.6 9.7 9.6 15.7 26.7 36.2 14.7 10.0 22.1 17.0 19.6 13.6 28.6 27.2 12.9 19.4 16.1 20.1 28.0 11.8 11.2 14.9 3.7 2.8 8.6 2.5 2.2 2.6 4.5 4.4 3.1 2.5 4.6 3.5 4.6 5.5 6.6 2.4 3.6 4.9 1.5 8.3 7.2 7.8 14.0 7.7 7.4 7.7 7.3 10.4 5.7 TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33096801 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "BEWO: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" 6.3 5.4 3.7 6.8 5.2 20.3 6.8 5.3 7.4 4.5 6.9 4.1 7.4 6.4 6.5 12.0 7.0 5.4 9.9 4.4 3.6 3.7 13.9 13.1 9.3 9.6 3.5 3.0 5.7 9.7 12.1 5.2 8.4 4.9 4.6 6.5 9.0 7.7 6.5 3.8 10.3 11.0 4.6 3.8 7.2 6.8 3.2 2.3 2.4 9.5 2.2 7.2 5.3 5.0 0.8 2.2 4.2 5.5 0.1 1.4 0.9 1.2 1.7 1.0 1.5 1.2 1.0 25.0 0.5 0.9 1.5 0.9 2.4 3.4 0.7 1.1 1.5 1.3 1.6 1.4 2.4 3.7 0.6 3.0 1.6 1.8 0.8 2.6 4.4 1.1 1.1 1.9 1.3 1.7 2.2 2.6 1.1 1.1 1.0 1.2 0.9 1.0 1.2 0.5 1.6 1.4 1.7 0.2 0.6 0.8 2.4 0.6 1.3 3.7 2.4 2.2 2.8 1.2 2.3 2.1 1.3 0.4 2.8 2.0 1.5 0.0 2.3 0.7 0.4 5.5 1.4 0.8 0.5 0.1 2.2 0.3 0.0 0.0 4.2 0.1 2.3 0.4 0.5 0.9 3.7 5.2 5.3 7.4 3.6 3.7 3.5 3.0 4.9 2.3 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715298 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.8 16.8 14.7 22.8 31.3 12.2 20.5 28.0 34.2 16.4 15.4 14.0 16.0 17.8 22.1 21.7 16.9 18.3 16.8 20.2 17.1 18.2 19.2 19.9 23.3 25.6 14.2 18.7 16.0 16.3 20.4 19.3 19.6 26.8 18.7 16.9 18.2 14.6 16.3 14.1 16.5 21.1 21.1 16.7 26.3 15.2 11.1 11.1 29.6 19.2 13.4 22.1 19.9 14.8 4.9 9.6 3.4 6.9 7.6 8.7 4.1 3.3 5.4 10.6 8.2 21.9 23.4 7.8 26.9 28.7 19.6 21.9 2.5 10.0 9.7 5.3 39.1 12.9 6.9 13.5 30.2 9.2 6.2 8.9 8.6 4.5 23.2 18.8 14.7 18.6 8.7 21.2 19.2 24.8 5.7 13.5 23.2 2.1 10.1 6.0 4.4 8.9 9.4 20.9 11.8 16.6 7.4 10.2 7.9 13.1 8.5 9.9 5.5 16.1 23.7 35.1 9.6 7.8 19.6 9.1 9.1 9.1 21.2 15.6 25.6 2.6 4.3 3.4 6.1 6.9 8.7 4.9 6.3 5.6 6.9 3.6 7.1 6.9 1.1 7.6 4.7 9.6 6.4 4.1 14.7 31.3 28.0 34.2 17.1 18.2 14.2 18.7 26.8 11.1 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171061339-171460408 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell line enhanced" "Detected in many" "AF22: 19.6;HEL: 26.6;HMC-1: 30.3;HUVEC TERT2: 19.5;WM-115: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 23 "basophil: 4.4;eosinophil: 10.5;gdT-cell: 4.2;MAIT T-cell: 5.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.7;naive CD4 T-cell: 6.7;naive CD8 T-cell: 3.8;NK-cell: 2.7;T-reg: 5.3" "Group enriched" "Detected in many" 29 "granulocytes: 10.5;NK-cells: 2.7;T-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol 9100 Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 2.2 5.4 29.0 7.4 30.9 4.9 3.6 21.1 26.1 1.9 10.9 12.2 4.1 25.8 4.3 2.1 5.6 4.3 7.1 11.2 30.9 14.8 5.6 4.6 11.3 7.9 11.4 18.3 2.6 5.2 0.7 9.0 3.1 13.6 5.6 9.5 3.5 2.9 7.3 23.2 1.6 25.6 6.0 14.5 5.8 9.2 10.7 21.1 3.7 7.1 2.2 6.9 6.4 2.6 0.2 0.0 10.5 0.1 2.7 6.7 1.1 0.3 0.5 19.6 2.0 0.3 0.0 4.6 4.1 1.1 3.2 2.2 17.5 7.3 0.0 1.4 3.7 6.0 2.8 1.1 3.5 0.1 4.3 26.6 1.5 0.0 9.4 5.2 30.3 2.8 2.9 1.9 0.4 19.5 9.6 0.0 0.5 0.4 1.6 6.7 8.0 7.6 0.0 5.0 7.0 6.3 0.0 0.9 1.0 2.5 0.2 4.3 8.8 1.3 0.2 0.0 3.4 8.9 3.0 0.0 0.0 0.0 0.9 5.9 22.7 4.4 0.1 10.5 4.2 0.0 5.2 0.0 5.0 3.7 0.0 0.2 6.7 3.8 0.1 2.7 0.1 0.0 5.3 1.1 29.0 30.9 21.1 22.2 30.9 14.8 11.4 18.3 13.6 21.1 TNKS "PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555914-9782346 "Enzymes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 9.1 13.4 17.8 8.7 19.6 14.6 14.0 26.5 22.3 18.1 8.9 17.0 12.5 8.5 14.9 25.3 7.7 11.9 8.9 9.5 18.6 17.9 9.0 9.1 10.3 12.9 28.7 17.2 19.2 10.2 23.9 20.0 11.0 20.1 11.5 10.0 10.9 9.4 11.7 22.1 15.6 9.8 11.0 21.0 8.7 10.1 26.3 21.8 15.6 13.7 4.4 11.7 10.8 13.6 6.8 3.6 7.4 2.8 2.9 4.8 1.2 6.0 8.0 20.5 12.3 12.9 17.4 7.6 9.3 10.6 7.6 8.6 4.7 4.8 12.9 3.9 9.1 6.4 11.6 8.7 11.0 3.3 6.0 9.1 7.3 10.7 11.7 4.7 5.6 12.3 10.6 7.9 15.6 10.2 8.5 13.9 14.0 3.9 11.7 7.1 13.3 4.7 9.5 12.6 3.7 9.1 12.3 20.8 15.3 7.3 7.0 13.2 4.7 7.0 13.7 12.5 7.7 8.5 6.9 4.8 7.8 9.2 13.5 6.6 12.0 4.8 2.3 1.8 4.4 2.2 2.4 4.2 3.5 4.2 2.8 6.8 4.2 4.8 7.4 2.9 2.8 3.6 1.7 1.2 17.8 19.6 26.5 22.3 18.6 17.9 28.7 17.2 20.1 21.8 TNKS2 "PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798312-91865276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules Microtubules "HPA036606: AB_10673470" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (4.16e-1)" "unprognostic (1.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" 17.6 16.3 16.7 23.0 18.6 26.9 18.4 27.9 20.0 18.8 13.9 18.3 18.3 11.9 18.9 18.8 24.7 16.7 17.2 12.2 16.6 14.9 14.6 16.8 17.0 22.9 20.3 14.9 26.0 19.3 20.8 26.7 47.5 16.1 16.7 14.3 16.1 21.4 16.0 39.7 23.9 16.5 18.9 18.0 22.8 15.8 9.5 17.9 42.9 24.5 21.0 23.8 18.6 18.9 3.6 5.2 3.8 2.5 3.3 3.5 1.4 14.3 12.3 25.3 21.4 17.9 16.4 28.3 15.5 28.4 19.0 23.4 10.9 11.8 13.6 7.5 20.2 15.6 15.8 12.0 26.9 13.7 15.3 11.2 11.8 12.1 17.5 21.6 16.8 16.6 15.9 19.2 34.3 17.8 8.3 15.1 19.7 7.7 18.6 14.8 12.7 8.3 17.5 15.8 10.3 13.0 15.6 6.6 11.9 15.6 6.9 19.3 16.7 15.1 19.1 10.3 8.7 13.5 14.7 19.1 15.6 17.7 13.5 16.3 9.1 1.0 2.5 3.8 3.5 2.3 3.0 3.5 3.3 3.2 3.4 3.6 2.8 2.4 2.5 3.3 2.2 5.2 1.7 1.4 16.7 18.6 27.9 20.0 16.6 14.9 20.3 14.9 16.1 17.9 TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein" Q9NS56 9 32540544-32552553 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm Nucleoplasm "HPA060640: , HPA065661: " "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-2)" "unprognostic (9.94e-2)" "prognostic favourable (7.07e-4)" "unprognostic (2.70e-1)" "unprognostic (3.61e-1)" "prognostic favourable (6.64e-6)" "unprognostic (1.22e-1)" "unprognostic (5.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" 16.0 12.5 12.7 8.5 16.0 22.9 13.7 18.6 15.1 14.0 12.2 9.6 9.5 8.8 12.9 11.4 13.1 10.5 11.7 9.3 15.9 9.6 14.6 17.4 10.6 10.0 20.1 5.2 17.5 13.2 19.6 19.5 17.9 14.8 13.1 10.3 9.2 11.0 10.8 10.9 10.2 16.8 12.3 17.8 12.4 10.7 18.9 15.0 15.5 15.6 9.8 10.5 16.3 16.0 5.2 4.9 33.4 5.9 7.1 7.4 3.4 8.0 7.5 10.3 9.0 12.6 11.4 6.5 10.3 9.7 8.6 10.0 4.6 4.1 13.1 5.9 10.2 5.4 12.1 11.7 12.1 10.9 6.6 44.2 13.0 5.8 7.8 12.5 12.2 9.2 13.1 12.4 8.8 10.4 7.6 6.8 13.9 4.3 11.2 23.1 13.7 7.6 11.6 9.2 5.9 11.4 8.5 5.1 8.2 10.3 5.6 6.7 5.7 7.2 10.9 9.4 9.6 4.9 7.6 4.8 7.7 14.2 8.7 7.2 4.2 14.6 4.9 10.0 5.0 4.6 5.4 4.6 5.4 5.8 4.9 5.2 7.4 7.2 33.4 7.1 5.9 4.0 6.3 3.4 12.7 16.0 18.6 15.1 15.9 9.6 20.1 5.2 14.8 15.0 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689779 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavourable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavourable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 11.2 14.5 12.7 12.6 15.3 9.6 16.8 8.1 20.3 14.1 11.7 13.7 5.3 8.8 14.8 8.9 16.9 12.2 12.6 9.9 12.1 11.3 12.7 13.6 10.6 18.2 13.1 12.8 15.3 10.1 11.8 15.7 14.9 12.1 15.5 11.4 12.6 13.8 12.2 12.4 16.8 11.2 12.7 10.6 13.2 13.3 26.4 11.8 21.9 16.6 13.1 21.1 14.3 12.7 14.7 19.1 21.7 12.4 16.2 18.5 12.2 3.9 2.7 5.8 5.1 6.1 5.1 5.2 5.5 5.2 7.4 5.4 7.7 2.5 9.5 8.4 4.6 6.2 7.4 6.4 6.4 2.3 3.7 9.6 2.7 6.9 8.1 6.2 69.0 6.7 7.8 5.1 5.0 4.8 6.4 4.2 6.2 5.8 9.3 10.3 4.7 9.2 5.4 5.2 5.6 4.9 4.3 6.9 3.6 6.7 13.6 27.0 4.9 6.8 4.9 8.6 5.0 5.6 6.1 4.6 5.7 7.6 5.0 4.7 4.0 21.7 12.4 20.6 13.7 11.5 15.8 14.7 14.8 15.6 12.6 14.2 16.4 14.0 2.0 16.2 10.2 19.1 18.5 12.2 12.7 15.3 8.1 20.3 12.1 11.3 13.1 12.8 12.1 11.8 TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155074 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 48.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019851 Enhanced "HPA019851: AB_1858213" "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavourable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favourable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favourable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" 5.3 13.2 11.5 6.6 10.2 4.9 5.6 13.1 14.3 4.6 18.2 4.1 6.2 18.4 6.5 10.1 8.9 4.1 7.6 6.5 9.0 8.0 40.2 36.2 6.5 6.2 9.3 7.5 3.8 9.4 12.9 11.6 3.3 8.5 6.2 19.4 6.9 12.9 7.2 7.0 5.7 29.4 6.2 7.2 9.4 6.6 4.1 7.5 5.4 48.2 6.3 5.3 6.4 5.6 1.6 16.9 3.7 23.8 5.4 8.3 8.3 11.7 3.6 4.0 9.8 6.6 12.9 9.8 13.7 15.2 11.7 18.3 8.3 2.9 1.5 10.2 18.0 5.9 5.6 9.8 19.6 7.7 8.1 9.7 6.1 12.1 7.2 4.4 8.8 7.4 10.6 13.0 8.3 16.2 19.1 2.8 8.5 5.4 4.5 6.1 6.6 10.3 5.7 9.8 6.6 13.6 12.1 6.5 5.0 8.9 15.9 17.5 11.5 4.5 6.9 26.9 5.2 14.0 19.3 4.1 18.2 3.8 9.6 6.1 26.9 3.4 12.0 3.7 6.5 23.8 8.3 1.5 5.3 6.2 16.9 1.6 4.8 6.5 1.2 5.4 19.6 3.7 8.2 8.3 11.5 10.2 13.1 14.3 9.0 8.0 9.3 7.5 8.5 7.5 TPP1 "CLN2, SCAR7" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612763-6619485 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" 13000000 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (4.31e-4)" "prognostic unfavourable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavourable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 37.4 64.6 32.2 28.8 36.2 43.0 23.1 15.1 33.3 24.0 26.8 41.7 13.2 28.0 32.0 22.3 20.3 18.0 26.9 25.6 24.5 25.1 36.0 45.1 35.9 42.3 31.0 29.3 22.0 14.8 35.1 30.0 56.4 25.4 19.4 28.2 43.4 18.4 29.1 15.4 15.5 31.4 42.4 32.8 69.0 19.8 17.9 24.7 21.7 24.0 9.1 26.9 25.6 29.4 9.4 43.5 12.8 38.9 7.0 15.3 26.2 4.9 10.1 5.1 9.6 59.4 32.9 3.9 9.8 46.5 7.6 13.3 4.2 21.3 7.2 6.5 24.7 14.9 10.0 13.7 11.6 7.1 5.7 5.8 5.2 11.2 44.9 8.3 35.3 49.3 22.4 8.9 19.8 32.5 11.0 21.6 22.2 6.1 2.6 10.3 3.6 12.2 6.5 4.3 14.0 13.5 7.8 0.6 3.9 10.5 7.8 18.3 5.2 15.9 37.1 22.0 6.3 19.8 3.5 18.3 17.9 2.5 28.0 19.6 11.5 12.8 37.7 8.9 10.7 38.9 8.7 9.4 8.5 11.0 43.5 8.5 5.8 7.6 6.9 7.0 26.4 24.2 15.3 26.2 32.2 36.2 15.1 33.3 24.5 25.1 31.0 29.3 25.4 24.7 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 173 "HMC-1: 294.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" "CAB016369: AB_628406, CAB022175: , HPA049153: , HPA049554: " "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favourable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 294.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell line enriched" "Detected in some" 8 "HMC-1: 81.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "HPA049153, HPA049554" Supported "Secreted to blood" 7500000 "HPA049153: , HPA049554: " "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.1 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 48 "HEL: 18.3;HMC-1: 27.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "CAB002215, CAB032871, HPA040182, HPA049554" Supported Uncertain "Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: , HPA049554: " "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.1 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 16.0 18.2 18.3 22.3 20.6 28.5 39.1 28.7 25.6 22.1 29.4 9.1 21.1 37.3 20.4 18.3 32.9 21.9 36.9 21.0 18.3 14.8 21.3 47.3 18.3 40.9 13.4 14.7 19.3 41.6 17.7 20.3 19.5 12.8 16.2 16.9 13.0 24.4 23.1 25.5 32.2 37.8 28.8 14.1 21.4 25.1 13.2 10.6 26.1 20.3 30.9 21.9 21.9 28.9 6.7 12.3 7.7 13.9 3.0 7.1 5.2 20.8 26.7 15.3 27.3 15.8 30.0 18.0 16.1 20.3 19.0 17.1 32.4 27.0 13.4 19.1 20.5 24.5 14.3 28.6 7.2 21.1 18.3 19.1 35.6 24.8 21.0 20.3 27.7 29.6 23.9 18.3 24.0 36.7 20.3 18.1 18.0 47.7 20.8 23.6 30.0 13.1 38.9 25.4 26.8 15.3 11.2 30.8 25.6 13.5 25.9 17.6 29.4 25.0 27.6 23.1 32.5 21.5 17.5 26.2 19.4 17.7 13.2 13.2 17.9 3.7 10.0 7.7 5.4 13.9 5.0 6.7 5.3 5.7 12.3 4.9 3.8 4.5 6.9 3.0 9.4 6.0 7.1 5.2 18.3 20.6 28.7 25.6 18.3 14.8 13.4 14.7 12.8 10.6 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670757 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.3;pancreas: 19.4" "Cell line enhanced" "Detected in some" "BJ: 20.5;BJ hTERT+: 19.9;EFO-21: 10.7;HBF TERT88: 7.3" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Region enhanced" "Detected in many" "cerebellum: 30.3" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" 6200000 "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favourable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 6.2 2.2 2.9 1.0 4.7 1.0 7.6 30.3 12.3 10.2 2.4 0.1 2.5 4.8 2.7 1.7 0.9 2.5 2.5 2.2 7.3 2.8 9.9 1.5 3.0 0.6 1.2 5.5 6.5 19.4 0.4 1.6 0.7 1.5 5.5 1.5 1.0 2.4 5.8 0.7 0.8 4.2 1.2 0.9 4.8 1.1 1.7 0.5 0.0 0.5 0.4 1.0 2.8 7.6 0.2 0.0 1.0 0.3 0.3 0.0 0.0 2.4 0.0 0.4 0.0 1.1 0.0 6.6 20.5 19.9 2.0 1.3 0.0 0.0 0.0 10.7 2.9 0.2 3.7 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.9 0.0 0.0 0.0 6.8 4.5 2.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 2.9 4.7 30.3 12.3 7.3 2.8 1.2 5.5 1.5 0.5 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: " "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavourable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 8.8 9.2 8.9 13.8 16.5 33.2 23.8 45.2 11.5 8.7 11.2 6.4 15.1 10.1 8.7 10.6 13.3 9.4 13.9 6.9 9.2 8.5 7.7 7.1 27.5 18.6 9.0 8.0 9.0 11.9 8.5 7.2 9.4 7.1 10.5 9.7 6.0 14.4 18.2 5.0 12.5 11.8 8.6 6.0 16.5 12.6 9.5 7.8 20.0 9.0 9.7 13.1 9.5 24.3 6.4 6.9 10.0 11.4 9.4 11.8 5.4 13.8 13.2 7.1 9.7 5.3 4.4 33.5 9.1 6.1 10.6 8.5 16.0 12.1 10.4 10.2 6.1 22.6 8.5 8.7 4.5 11.6 20.5 8.6 12.2 8.6 14.5 10.9 13.2 5.9 14.0 10.9 5.5 5.2 19.7 13.5 5.4 9.0 13.1 17.2 18.1 11.7 12.9 6.4 12.6 6.9 17.0 11.8 21.7 7.6 21.6 12.0 15.2 18.2 5.8 6.7 9.5 15.7 18.8 13.9 9.2 9.2 8.4 8.7 10.6 6.1 6.9 8.3 9.6 8.2 10.2 5.8 10.7 11.8 6.9 6.4 6.3 8.4 10.0 9.4 11.4 5.5 9.8 5.4 8.9 16.5 45.2 11.5 9.2 8.5 9.0 8.0 7.1 7.8 TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687302-116701300 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease mutation, Limb-girdle muscular dystrophy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" "Intermediate filaments" "HPA050060: " "unprognostic (2.47e-2)" "unprognostic (7.06e-3)" "unprognostic (5.50e-2)" "unprognostic (3.63e-1)" "unprognostic (5.08e-2)" "prognostic unfavourable (4.53e-4)" "prognostic unfavourable (4.72e-4)" "unprognostic (2.41e-3)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (6.03e-2)" "unprognostic (7.06e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-3)" "unprognostic (9.77e-2)" 9.5 9.1 6.6 5.8 11.5 0.8 8.0 23.2 17.1 12.8 7.9 7.2 6.2 6.7 17.0 8.0 8.8 15.9 8.2 8.9 5.7 7.3 6.2 5.0 6.3 8.4 5.7 9.8 12.6 12.5 12.2 7.7 7.0 9.1 10.3 7.4 10.4 10.9 9.2 23.9 6.6 8.9 12.9 5.3 6.9 6.8 6.5 2.2 9.4 8.4 6.2 8.3 11.1 8.8 6.1 3.5 0.2 2.6 5.6 16.0 4.7 6.4 14.9 8.8 9.7 17.9 12.9 6.7 12.1 13.3 13.8 11.6 9.9 7.1 6.7 5.4 18.5 13.9 10.7 13.6 12.6 5.9 5.2 3.6 9.6 6.0 9.3 2.4 11.9 11.0 12.3 13.0 7.7 8.9 5.0 5.7 16.1 8.3 6.4 0.0 8.0 9.0 7.6 23.7 4.4 5.6 15.2 8.8 4.5 9.5 6.6 6.9 18.4 2.4 11.0 12.8 10.3 9.4 9.1 9.4 2.5 10.5 10.7 1.6 12.5 0.0 1.3 0.0 9.3 2.6 7.2 6.1 8.2 7.4 1.8 4.4 8.3 8.4 0.2 5.6 2.1 3.5 16.0 4.7 6.6 11.5 23.2 17.1 5.7 7.3 5.7 9.8 9.1 2.2 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392777-114511160 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favourable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favourable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 15.2 12.8 16.9 18.4 19.9 27.1 17.1 38.3 21.8 16.9 14.3 11.0 21.9 10.9 19.8 38.3 16.4 15.0 15.6 10.8 18.1 12.5 17.3 15.0 14.3 15.2 12.1 18.0 19.8 15.7 21.8 22.4 27.2 15.2 16.5 13.0 10.7 16.4 19.1 14.3 19.5 14.8 20.2 12.9 14.9 14.1 29.0 16.3 20.5 17.9 9.8 16.6 17.9 28.7 3.4 4.0 12.2 2.8 4.7 4.4 1.0 12.9 7.0 13.2 9.9 5.6 5.9 22.5 6.6 7.0 9.2 9.8 7.9 5.5 13.8 6.8 7.7 7.5 12.0 7.7 12.7 10.4 7.1 13.3 9.2 9.1 6.2 16.8 11.1 5.6 5.7 10.9 11.2 7.7 16.6 9.8 8.8 48.5 16.9 7.1 17.8 7.1 14.6 20.2 4.5 6.6 20.4 9.2 9.7 12.5 15.1 11.9 6.9 9.2 8.6 6.4 10.5 14.8 9.2 6.9 6.4 14.5 9.1 9.8 18.2 12.2 1.6 7.4 3.5 1.8 3.1 3.4 3.7 3.7 2.0 2.2 2.9 4.4 4.8 4.7 2.8 4.0 2.0 1.0 16.9 19.9 38.3 21.8 18.1 12.5 12.1 18.0 15.2 16.3 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663557-5938619 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 12.5 15.0 3.7 11.6 6.7 3.0 10.7 2.4 5.1 14.2 8.5 4.8 20.1 8.4 16.1 19.9 12.0 11.9 9.9 7.8 5.6 2.9 15.1 16.2 15.2 9.2 6.5 2.9 15.3 24.8 6.1 9.2 12.2 8.8 11.8 8.3 11.8 22.0 12.4 3.0 6.5 13.2 12.0 9.0 19.8 9.5 7.7 6.5 24.9 20.5 7.9 13.3 14.8 12.3 3.9 11.7 13.8 9.8 5.9 5.4 4.6 4.6 7.2 12.3 8.6 13.7 12.6 3.6 9.9 18.6 20.3 27.5 7.3 9.3 3.0 7.8 9.7 7.6 10.0 14.5 9.2 6.4 2.7 9.0 5.0 5.8 12.2 6.6 9.7 9.5 13.0 6.7 17.8 31.3 9.4 6.1 17.0 2.1 5.4 3.0 5.6 5.1 8.4 2.6 0.8 14.1 8.9 0.3 0.7 7.0 10.1 4.4 5.2 3.8 23.6 9.6 12.7 1.8 2.4 5.5 3.8 1.2 8.9 4.4 9.8 10.2 9.8 12.9 5.4 9.8 5.3 3.9 4.1 4.3 11.7 3.9 3.4 4.9 13.8 5.9 9.2 9.7 3.3 4.6 3.7 6.7 2.4 5.1 5.6 2.9 6.5 2.9 8.8 6.5 TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051304-26068436 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 271.4" "Group enriched" "Detected in some" 38 "ASC diff: 10.5;SK-MEL-30: 33.5" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" 3.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 1.2 1.7 0.0 0.6 38.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.5 0.0 3.6 1.0 0.0 271.4 0.6 0.1 0.9 0.1 0.0 0.1 0.1 0.0 0.0 1.7 12.7 0.8 1.2 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: " "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavourable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.2 4.4 10.6 5.0 22.7 29.8 12.1 11.3 13.5 9.1 10.5 2.8 4.8 2.8 8.5 15.4 3.7 1.7 5.3 18.9 7.8 2.5 1.5 11.8 3.5 11.8 3.7 4.2 13.9 5.6 32.2 10.3 8.0 0.3 1.9 22.0 2.3 0.0 2.6 2.6 4.0 2.8 6.4 9.4 8.9 5.5 4.8 19.5 9.6 2.5 5.0 1.5 0.5 18.6 17.6 11.2 12.7 13.3 0.0 0.6 3.6 62.5 2.4 4.1 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 TRIP12 KIAA0045 ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763838-229923239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" "Nuclear speckles" "HPA036835: , HPA045893: " "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavourable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 29.6 28.1 23.6 25.4 26.9 26.9 23.1 20.5 26.2 24.0 23.1 26.2 24.3 14.3 25.3 26.3 30.6 19.9 20.7 35.9 19.0 19.3 26.2 24.9 26.2 26.5 23.1 20.5 24.3 18.8 32.4 33.1 27.2 24.8 25.8 21.3 22.3 25.5 22.0 62.7 23.6 22.0 26.2 23.3 32.5 23.4 77.1 24.0 42.2 28.0 21.5 31.5 26.5 27.4 7.0 9.1 25.8 12.0 9.1 12.7 6.1 23.8 26.9 24.7 20.7 23.6 28.7 23.0 36.8 25.0 26.7 29.8 21.5 19.2 9.3 27.0 32.8 18.7 36.0 26.2 39.2 38.2 13.1 64.8 22.6 19.0 20.4 48.7 42.4 24.8 20.2 44.4 28.5 34.8 47.8 10.0 30.5 18.1 27.2 16.8 19.3 12.3 24.8 48.8 8.2 19.8 41.0 25.1 17.9 0.5 12.4 25.3 12.5 29.8 48.3 34.6 24.6 22.5 28.4 17.4 19.9 30.5 26.4 19.2 29.0 18.8 9.9 15.7 9.5 11.3 9.7 7.0 8.8 9.2 9.1 6.8 7.3 7.0 25.8 9.1 12.0 9.0 12.7 6.1 23.6 26.9 20.5 26.2 19.0 19.3 23.1 20.5 24.8 24.0 TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39841022-39883511 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024174 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA024174: AB_1858346" "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavourable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavourable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavourable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" 9.5 10.3 12.9 10.4 19.1 8.0 19.8 25.8 18.4 15.1 13.4 15.9 22.7 11.4 19.3 21.3 19.8 18.4 9.1 15.9 12.5 12.0 14.6 13.2 11.9 14.8 13.9 10.4 16.7 27.7 14.1 26.7 17.6 14.4 21.4 15.8 13.5 15.1 23.9 10.1 22.9 11.7 18.0 9.8 14.0 12.9 17.3 17.9 15.4 19.2 9.4 14.7 17.2 17.5 3.9 13.4 0.9 6.6 2.4 5.2 2.8 14.5 6.7 14.6 14.9 7.3 11.0 22.0 9.7 13.0 15.6 17.6 12.9 19.2 8.4 12.8 8.2 14.8 21.0 16.7 21.9 10.3 10.6 18.0 15.6 8.0 16.9 17.5 9.9 9.3 15.1 19.5 19.3 12.5 24.4 10.2 9.7 7.1 13.3 18.8 19.6 6.1 14.2 18.3 19.3 14.8 18.7 16.6 11.1 13.9 9.5 10.6 10.5 30.0 8.9 10.4 12.8 18.0 16.0 13.8 10.8 17.1 13.2 17.9 9.0 0.0 6.6 0.9 2.7 4.9 5.2 3.9 2.6 2.9 13.4 3.2 3.4 3.5 0.1 2.4 5.8 11.6 2.7 2.8 12.9 19.1 25.8 18.4 12.5 12.0 13.9 10.4 14.4 17.9 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavourable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 15.5 15.0 19.1 19.8 23.5 23.1 16.6 19.5 22.6 15.0 16.3 17.3 15.5 14.9 19.2 19.0 17.6 19.6 19.4 13.2 15.7 13.4 14.4 17.3 13.5 26.8 22.1 14.7 29.1 23.8 16.3 14.4 14.4 21.9 18.1 14.5 10.9 14.9 15.6 21.4 22.1 16.1 16.5 12.4 25.0 16.3 16.8 20.1 12.2 15.6 12.1 19.6 17.3 18.8 11.2 14.9 3.1 15.7 4.3 10.2 8.5 15.3 10.4 11.3 19.1 11.5 14.7 16.2 17.3 8.7 19.1 16.6 11.1 12.7 19.3 22.7 9.3 14.3 18.8 15.2 8.9 12.6 26.3 15.3 26.7 18.6 20.8 30.7 18.1 20.8 20.5 19.9 18.7 14.0 33.2 6.2 11.8 17.0 12.4 33.2 26.7 24.4 21.0 14.5 26.6 11.9 15.7 26.8 12.2 10.8 22.5 18.0 8.7 17.2 15.6 27.6 10.7 16.6 30.3 10.7 20.7 17.8 12.9 32.5 14.3 1.2 15.7 0.5 8.1 11.9 7.7 10.4 8.6 7.7 14.9 11.2 10.2 7.7 3.1 4.3 7.5 8.8 5.6 8.5 19.1 23.5 19.5 22.6 15.7 13.4 22.1 14.7 21.9 20.1 TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986430-126039276 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030473 Approved "Nuclear bodies" "Nuclear bodies" "HPA030473: " "unprognostic (2.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.44e-1)" "unprognostic (1.13e-2)" "unprognostic (7.62e-2)" "unprognostic (9.69e-2)" "unprognostic (2.12e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-2)" "unprognostic (5.73e-2)" "unprognostic (7.35e-2)" "unprognostic (1.06e-2)" "unprognostic (4.74e-3)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" 10.0 12.6 14.3 12.5 17.7 3.6 15.5 33.9 19.4 17.9 12.6 9.4 11.2 16.1 25.9 15.1 13.2 12.8 12.9 16.1 15.0 12.6 18.8 28.0 10.1 12.4 12.7 16.4 19.2 10.4 15.9 38.1 13.3 15.4 12.8 15.0 14.8 11.7 13.8 10.6 7.4 20.6 15.7 15.2 9.6 12.9 9.8 11.1 8.0 18.0 9.8 13.7 11.5 12.5 8.0 4.7 1.3 2.0 7.5 11.7 4.0 8.5 6.4 13.1 2.8 6.8 7.4 7.7 7.3 11.2 8.0 11.9 19.7 9.0 12.1 13.5 4.8 11.9 14.1 7.5 12.3 9.7 20.3 9.4 12.8 24.6 11.7 15.5 2.6 7.4 7.1 9.4 15.4 3.6 21.4 2.4 8.3 13.1 7.1 8.1 9.2 8.3 4.9 9.9 7.2 9.4 5.4 16.5 7.7 9.0 8.2 15.9 6.4 12.5 3.6 5.3 4.1 12.3 12.7 6.6 0.7 3.3 10.9 12.0 9.3 1.3 2.0 0.0 6.8 1.5 11.7 8.0 9.1 7.5 4.1 6.7 11.4 10.4 0.3 7.5 0.7 4.7 6.8 4.0 14.3 17.7 33.9 19.4 15.0 12.6 12.7 16.4 15.4 11.1 TRMT1L C1orf25 ENSG00000121486 "TRNA methyltransferase 1 like" Q7Z2T5 1 185118098-185157072 "Predicted intracellular proteins" "Behavior, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026728 Uncertain Approved Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA026728: AB_1845641" "unprognostic (1.07e-2)" "unprognostic (1.31e-1)" "unprognostic (8.55e-3)" "unprognostic (2.96e-1)" "unprognostic (1.46e-2)" "unprognostic (8.95e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-2)" "unprognostic (2.32e-1)" "unprognostic (2.46e-3)" "unprognostic (1.32e-1)" "unprognostic (8.75e-2)" "unprognostic (1.16e-2)" "unprognostic (7.44e-2)" "unprognostic (9.45e-2)" "unprognostic (7.87e-2)" "unprognostic (2.26e-1)" 7.6 12.9 9.4 10.1 12.8 5.9 8.9 14.2 11.3 10.5 10.0 9.6 9.6 9.6 9.3 11.3 10.5 12.6 8.2 13.2 10.3 10.6 15.3 16.0 10.3 11.1 11.2 9.1 13.7 8.3 18.0 26.9 9.7 11.9 11.7 8.5 5.2 7.6 10.0 27.4 5.5 8.7 8.5 12.4 12.8 8.4 29.4 12.8 16.5 12.4 7.6 13.0 11.8 12.2 16.2 12.1 19.0 15.8 11.0 12.7 8.1 8.0 14.8 10.2 7.6 15.1 13.9 14.5 7.8 7.0 10.7 11.2 13.4 15.5 8.8 19.5 5.3 10.4 17.1 10.2 10.5 10.4 7.4 8.4 11.2 13.6 10.5 12.4 14.0 6.7 13.9 10.9 11.0 11.7 22.0 12.1 12.7 6.8 9.4 7.2 16.9 3.1 11.1 14.7 14.0 10.3 8.9 9.1 8.1 15.2 14.8 10.5 15.1 7.0 11.2 9.8 7.8 6.7 10.4 19.5 26.1 14.0 6.4 11.0 9.4 16.8 9.8 19.0 7.4 13.4 7.9 11.7 9.7 8.9 12.1 16.2 12.2 9.5 11.1 11.0 15.8 5.1 12.7 8.1 9.4 12.8 14.2 11.3 10.3 10.6 11.2 9.1 11.9 12.8 TRMU "FLJ10140, MTO2, TRMT" ENSG00000100416 "TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA000824: , HPA035273: AB_10602901, HPA043300: " "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavourable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favourable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavourable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 8.5 16.1 11.5 9.9 16.0 6.4 7.5 17.8 16.0 9.7 8.7 11.5 10.2 10.9 12.1 18.0 10.9 6.2 7.3 16.8 11.3 11.9 20.5 18.8 7.1 10.2 15.7 11.8 8.0 22.7 20.0 13.6 9.7 11.2 8.7 10.2 9.0 12.5 15.5 17.8 9.8 7.6 9.4 11.4 8.7 9.2 8.3 13.9 6.5 9.6 8.3 9.8 7.1 9.1 6.2 7.6 3.9 9.6 7.5 11.3 6.3 10.8 9.9 4.3 9.6 8.0 5.7 10.7 11.3 8.0 16.1 12.5 14.0 2.7 7.1 8.0 10.1 9.7 18.1 10.1 13.8 4.6 24.4 8.4 15.2 16.5 6.9 16.1 5.8 5.4 11.4 16.6 5.3 10.3 11.7 1.7 9.7 11.4 6.2 13.2 16.1 17.5 7.4 9.2 13.1 8.0 7.5 10.2 12.3 10.0 11.8 18.9 6.7 6.7 7.5 7.2 12.8 10.1 12.6 4.2 4.5 7.6 10.1 11.7 14.4 0.0 6.8 3.9 11.1 9.4 9.4 5.7 9.4 10.0 7.6 6.2 8.6 8.0 1.4 7.5 9.6 6.0 11.3 6.3 11.5 16.0 17.8 16.0 11.3 11.9 15.7 11.8 11.2 13.9 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.1;intestine: 19.5" "Cell line enhanced" "Detected in some" "BEWO: 7.5;HeLa: 4.4;Karpas-707: 2.5;RT4: 7.2;U-266/70: 2.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 16.1;neutrophil: 6.6" "Lineage enriched" "Detected in single" 30 "granulocytes: 16.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 2.9 0.0 1.3 0.5 1.2 2.5 1.1 1.3 1.2 0.8 13.3 0.2 1.0 7.2 0.4 0.2 0.6 0.4 1.0 0.5 1.9 1.2 3.1 0.2 1.5 0.2 2.6 0.0 0.4 0.2 3.8 4.9 0.2 1.6 1.7 17.5 0.4 1.1 0.0 1.6 0.8 19.5 0.7 5.0 3.9 0.2 1.7 0.5 1.6 0.3 1.1 2.1 0.5 0.6 0.3 0.3 16.1 0.1 0.5 0.1 0.0 0.0 1.6 0.2 0.2 0.0 0.0 7.5 0.1 0.0 0.0 0.1 2.1 0.2 0.6 0.0 0.1 0.3 0.5 0.5 0.0 0.1 0.2 0.2 4.4 0.3 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.2 0.0 2.5 0.1 0.9 0.0 0.1 0.6 0.2 0.0 0.0 0.3 0.0 7.2 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 1.1 0.2 0.0 2.7 0.0 0.2 0.1 0.1 0.3 16.1 0.1 1.9 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 6.6 0.5 0.1 0.3 0.0 0.0 1.3 1.2 1.3 1.2 1.9 1.2 2.6 0.0 1.6 0.5 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686815 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 91.8" "Cell line enhanced" "Detected in all" "U-2197: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: " "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 13.3 10.8 6.6 14.7 9.0 12.8 12.1 19.5 9.3 11.8 11.7 8.1 9.7 9.9 16.5 10.7 9.4 11.0 8.2 19.1 5.5 4.9 16.0 20.0 10.8 10.6 12.4 5.2 16.6 11.6 91.8 14.6 14.3 10.2 9.7 10.3 28.6 11.5 13.5 10.8 11.7 12.8 12.8 9.8 11.1 10.3 6.9 10.0 14.5 12.6 6.9 12.6 12.9 12.3 7.0 4.7 4.4 3.4 5.7 7.6 2.0 8.3 8.3 7.0 7.7 20.2 15.2 8.5 10.6 14.7 6.7 8.9 11.4 4.6 18.2 5.2 12.2 14.1 9.3 7.8 9.7 10.1 5.6 14.5 12.8 6.0 18.4 15.0 11.3 14.1 9.2 7.6 14.4 5.4 16.4 14.0 12.2 13.1 9.6 7.3 5.3 5.1 10.6 9.7 8.9 9.4 19.8 5.8 7.4 7.3 11.6 14.2 7.3 16.3 8.2 10.7 5.1 49.9 12.1 9.5 21.0 17.5 11.7 30.7 9.9 3.8 3.4 3.9 6.6 3.2 7.6 5.6 4.8 4.4 3.7 7.0 4.4 5.2 4.4 5.7 3.2 4.7 4.8 2.0 6.6 9.0 19.5 9.3 5.5 4.9 12.4 5.2 10.2 10.0 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027827 Enhanced "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19130808-19132623 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "testis: 95.7" "Cell line enhanced" "Detected in some" "HL-60: 1.7;SCLC-21H: 3.4;THP-1: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.0 1.6 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 0.0 1.2 0.0 0.8 0.0 0.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.7 3.2 0.8 1.4 0.5 0.0 0.2 0.1 0.9 0.3 0.0 0.3 1.2 0.0 0.0 1.0 0.4 0.0 0.0 0.5 0.1 0.8 0.3 0.7 0.2 0.5 0.2 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.6 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 0.0 3.1 5.8 0.0 0.6 1.4 1.5 1.5 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" "Cell Junctions" "HPA060660: , HPA077103: " "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.0 3.9 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 3.8 0.0 0.1 0.0 1.6 3.0 3.4 4.8 3.0 0.0 1.5 3.7 0.0 0.0 0.0 0.6 0.1 1.3 2.0 0.0 3.8 3.6 1.6 0.7 3.2 2.9 1.5 2.6 0.0 5.2 2.2 2.0 2.7 2.5 0.8 1.6 1.7 1.4 2.9 1.8 3.7 1.3 4.2 4.8 4.7 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515685 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "testis: 50.8" "Cell line enhanced" "Detected in many" "BEWO: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.9 1.2 1.0 1.2 1.5 1.3 1.0 0.9 1.9 0.9 1.1 2.2 1.6 2.1 0.9 3.7 1.1 1.1 1.0 0.7 1.2 0.8 1.8 2.2 0.7 1.2 2.5 1.0 0.9 3.3 1.1 1.0 0.6 1.3 1.4 0.6 0.9 1.3 1.0 1.0 2.7 1.9 1.2 1.9 2.1 1.7 50.8 1.7 3.1 2.0 0.1 1.7 1.1 1.0 3.1 1.0 2.2 0.7 0.4 3.8 0.8 1.7 2.7 0.1 1.1 0.4 1.0 8.1 1.1 0.5 0.6 0.3 4.3 1.3 1.4 2.0 0.1 1.4 0.5 1.1 0.2 1.1 2.0 0.7 1.7 0.9 1.2 0.9 3.2 0.7 1.0 0.6 1.9 0.3 1.9 0.8 0.0 0.5 3.4 2.0 3.7 4.5 2.8 0.7 1.2 0.1 0.5 0.6 2.9 1.6 0.4 1.4 2.7 0.7 0.3 2.0 0.6 4.0 1.7 3.6 1.5 0.8 2.2 1.2 1.9 0.0 0.6 2.2 0.8 0.2 1.1 3.1 1.7 2.0 0.3 1.9 3.8 2.1 1.1 0.4 0.7 1.0 1.0 0.8 1.0 1.5 0.9 1.9 1.2 0.8 2.5 1.0 1.3 1.7 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: " "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 22.9 22.1 34.0 18.7 36.5 12.0 23.4 39.2 40.0 34.9 20.6 15.9 26.7 13.0 21.6 33.3 15.3 19.5 19.0 21.5 29.1 16.5 21.4 17.0 15.4 14.3 17.7 27.5 34.5 25.8 27.4 50.4 15.2 34.7 28.9 19.9 16.1 24.5 25.4 21.6 16.1 16.8 21.6 21.7 13.6 21.3 19.5 19.9 19.7 35.4 11.1 15.1 23.3 18.9 10.6 12.8 4.8 5.7 9.1 18.6 3.8 21.4 7.6 35.7 6.7 34.5 50.2 12.4 23.6 29.4 10.7 14.5 10.1 10.8 18.5 8.2 39.5 7.0 10.7 14.5 15.1 19.6 7.7 37.4 11.5 13.1 12.6 20.8 12.1 25.9 9.0 10.8 9.7 15.8 22.5 21.8 20.0 16.6 20.2 5.4 10.1 13.0 27.1 17.1 9.7 12.4 16.6 27.3 20.8 29.3 16.8 15.2 19.0 8.2 20.5 15.3 6.1 18.7 8.8 21.9 15.7 18.5 25.2 20.9 11.5 2.9 4.4 4.8 9.1 4.8 13.6 9.5 10.6 12.3 7.9 10.6 18.6 11.3 0.7 9.1 5.7 12.8 7.2 3.8 34.0 36.5 39.2 40.0 29.1 16.5 17.7 27.5 34.7 19.9 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavourable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.7 1.1 3.5 13.6 15.5 9.6 22.7 27.8 10.9 10.2 19.8 12.1 6.6 17.4 21.2 9.5 31.7 18.0 17.1 18.3 10.7 8.9 0.0 21.5 12.0 0.4 1.0 15.9 10.2 12.8 20.0 20.5 19.3 9.9 12.3 15.6 14.2 9.7 11.0 43.9 8.2 5.7 8.6 16.6 9.7 9.1 9.9 5.6 9.3 16.4 5.3 10.2 10.2 6.6 24.8 4.6 15.5 11.0 3.6 20.1 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482154-112541739 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA066819: " "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavourable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 4.4 4.0 9.9 4.2 11.9 7.1 11.3 5.0 12.5 3.3 4.1 9.2 2.5 3.1 4.6 4.2 5.2 3.2 4.9 10.3 9.4 6.5 3.9 3.3 5.9 4.4 8.1 5.3 3.2 3.8 4.1 2.4 5.3 5.9 3.2 3.9 2.6 3.0 3.7 13.1 6.0 3.2 5.8 5.4 4.0 3.2 3.0 6.5 5.1 4.2 5.2 3.8 4.8 2.9 1.8 1.2 2.7 1.3 1.0 1.3 0.5 3.7 2.8 3.6 8.1 4.4 6.2 1.4 6.4 5.3 6.8 5.9 3.5 1.3 3.5 3.6 5.5 2.6 6.3 3.3 8.3 2.4 3.6 2.9 4.0 4.4 1.9 4.1 1.5 2.8 2.3 9.9 5.3 5.8 4.8 2.8 5.3 1.9 3.5 2.3 3.1 5.8 3.8 4.1 1.9 2.1 2.9 7.7 5.4 5.0 1.7 8.9 1.7 2.4 5.7 8.1 5.9 6.3 4.7 1.5 3.1 2.9 9.0 3.1 3.4 2.7 1.3 1.0 1.3 0.8 1.1 0.8 1.0 1.0 0.4 1.8 0.9 1.1 2.4 1.0 1.1 1.2 0.8 0.5 9.9 11.9 5.0 12.5 9.4 6.5 8.1 5.3 5.9 6.5 TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173884-1197935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 48.2" "Cell line enriched" "Detected in single" 24 "SCLC-21H: 22.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "pons and medulla: 2.2" "Cell type enriched" "Detected in single" 29 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 29 "NK-cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain "HPA042712: AB_10797019" "unprognostic (1.74e-1)" "unprognostic (7.95e-2)" "unprognostic (2.66e-3)" "prognostic favourable (1.61e-5)" "unprognostic (5.33e-2)" "unprognostic (2.68e-3)" "unprognostic (4.93e-3)" "unprognostic (2.14e-3)" "unprognostic (4.50e-1)" "unprognostic (3.69e-2)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "unprognostic (6.00e-4)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.12e-1)" "unprognostic (4.39e-2)" 1.2 0.0 0.1 0.1 0.5 0.0 0.6 0.1 0.2 1.7 0.1 1.0 0.1 0.0 0.2 1.1 0.1 10.9 0.1 0.1 0.3 0.3 0.1 0.1 3.1 0.1 0.1 0.3 0.7 0.1 0.0 1.3 1.5 2.2 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.5 48.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.3 0.3 0.1 0.3 2.2 0.3 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell line enhanced" "Detected in many" "RH-30: 4.8" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: " "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.7 0.0 0.0 0.0 2.3 2.0 3.7 2.6 1.0 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.4 2.1 1.2 0.4 0.4 1.6 2.5 0.4 1.8 1.3 4.8 1.3 0.0 0.6 1.0 1.7 0.4 1.3 0.0 0.7 2.4 1.6 0.0 0.0 0.9 0.4 3.5 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Enhanced Nucleoplasm 16000000 Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favourable (1.78e-4)" "unprognostic (1.21e-2)" 45.6 63.0 56.0 47.2 50.6 42.0 38.3 58.1 75.7 48.0 39.3 55.9 44.9 36.3 52.9 34.1 59.4 56.0 39.9 48.7 49.5 39.9 51.1 60.0 42.0 48.2 47.7 62.3 57.6 34.9 78.8 55.5 39.1 47.6 40.2 35.5 41.0 47.5 45.7 77.7 56.1 37.9 59.4 35.5 53.4 38.7 36.0 48.6 52.7 65.0 43.9 54.0 39.2 52.7 28.9 30.6 32.6 36.0 25.6 29.0 24.1 45.8 47.6 54.5 82.8 37.3 34.0 24.1 30.5 32.5 43.9 35.8 37.8 35.0 34.2 20.3 61.0 44.3 68.3 64.9 32.3 28.3 69.4 21.4 52.8 30.3 26.3 36.0 46.2 31.9 34.0 63.8 49.8 57.5 23.2 30.8 43.5 58.1 33.9 31.9 58.0 74.4 39.5 38.0 58.2 35.1 49.4 35.3 26.5 90.9 44.2 20.2 61.5 22.5 42.0 33.0 38.3 47.5 28.4 21.1 21.9 48.8 33.9 25.8 39.4 17.4 27.0 27.4 29.0 36.0 25.4 28.9 24.0 25.9 30.6 22.0 19.1 23.4 32.6 25.6 32.8 20.8 28.2 24.1 56.0 50.6 58.1 75.7 49.5 39.9 47.7 62.3 47.6 48.6 UBA2 "ARX, FLJ13058, HRIHFB2115, SAE2" ENSG00000126261 "Ubiquitin like modifier activating enzyme 2" Q9UBT2 19 34428352-34471251 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041436 Supported Supported Nucleoplasm 9400000 Nucleoplasm "HPA041436: " "unprognostic (2.37e-1)" "unprognostic (3.17e-1)" "unprognostic (2.13e-2)" "unprognostic (1.36e-3)" "unprognostic (6.39e-3)" "unprognostic (8.72e-3)" "prognostic unfavourable (3.76e-4)" "unprognostic (1.96e-2)" "unprognostic (2.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.58e-1)" "unprognostic (2.65e-2)" "prognostic unfavourable (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (2.11e-2)" "unprognostic (2.00e-1)" "unprognostic (1.88e-1)" 49.2 23.5 25.1 29.5 28.4 30.6 70.9 44.3 30.4 26.5 25.4 20.7 24.0 17.8 32.3 24.2 27.4 25.1 23.7 31.0 25.6 27.7 22.8 25.5 24.5 37.8 26.9 23.2 30.3 29.4 28.8 26.8 39.1 25.1 25.1 23.9 20.7 20.9 31.5 56.3 29.2 20.4 28.8 27.4 28.6 20.9 56.7 19.9 55.9 25.9 27.1 34.4 29.2 38.9 8.6 10.8 7.7 6.2 8.5 13.0 3.6 28.6 42.0 43.1 17.8 23.4 19.2 17.6 22.4 19.3 29.0 32.5 35.9 17.5 53.7 34.7 18.2 11.7 45.6 17.5 41.0 38.4 30.8 57.0 21.5 35.9 30.2 45.2 24.8 13.8 22.3 20.5 36.2 22.7 56.4 30.5 25.4 28.7 34.8 25.1 32.3 14.6 27.7 29.7 23.9 20.4 30.1 36.7 36.0 20.4 18.8 30.1 13.5 55.5 14.6 32.7 22.8 20.9 40.1 32.2 45.7 52.0 20.7 34.6 28.7 5.9 4.8 7.7 8.4 5.0 11.2 8.5 10.5 12.1 6.0 8.6 13.0 10.4 0.6 8.5 6.2 10.8 8.0 3.6 25.1 28.4 44.3 30.4 25.6 27.7 26.9 23.2 25.1 19.9 UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" 9600 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: AB_10670578, HPA034874: , HPA065335: " "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (5.56e-3)" "unprognostic (9.26e-2)" "unprognostic (9.35e-3)" "unprognostic (5.53e-2)" "prognostic unfavourable (8.57e-4)" "unprognostic (1.08e-1)" "unprognostic (6.18e-2)" "unprognostic (1.60e-3)" "unprognostic (9.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-3)" "unprognostic (2.61e-3)" "unprognostic (9.24e-2)" "unprognostic (7.80e-3)" "unprognostic (2.52e-1)" 19.1 25.3 29.7 22.2 31.0 53.7 26.8 30.9 31.4 20.3 19.7 31.3 15.9 16.1 22.8 25.4 25.4 19.5 18.4 38.2 23.8 22.7 24.7 17.6 19.3 28.7 37.5 21.2 20.4 15.1 17.9 28.0 27.8 40.8 22.6 22.6 21.8 28.0 20.4 25.0 27.6 21.9 24.0 30.2 27.8 17.3 13.5 31.9 28.4 18.2 17.2 31.0 22.9 20.4 18.9 22.3 35.6 27.8 20.2 22.2 26.0 26.8 11.4 28.1 17.1 26.3 34.9 21.7 24.1 27.3 26.3 26.5 14.1 19.0 20.5 7.0 25.9 15.5 21.6 27.6 30.0 37.3 13.7 27.7 21.5 14.2 20.3 27.1 23.3 27.4 18.5 24.8 20.8 33.8 11.4 17.6 34.6 9.6 17.8 18.3 24.9 9.8 13.9 20.8 18.8 41.9 34.4 12.1 16.9 25.4 18.5 20.6 12.6 26.7 25.6 20.0 17.6 25.9 33.4 20.2 32.3 24.4 20.5 30.2 25.4 34.7 25.4 35.6 14.3 27.8 16.1 18.9 18.9 17.6 22.3 16.0 17.9 18.0 24.4 20.2 27.7 11.4 22.2 26.0 29.7 31.0 30.9 31.4 23.8 22.7 37.5 21.2 40.8 31.9 UBA6 "FLJ10808, UBE1L2" ENSG00000033178 "Ubiquitin like modifier activating enzyme 6" A0AVT1 4 67612652-67701179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037001 Approved Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037001: AB_10672787" "unprognostic (2.52e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-3)" "unprognostic (2.81e-1)" "unprognostic (3.67e-2)" "unprognostic (4.92e-2)" "unprognostic (3.55e-3)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-2)" "unprognostic (3.38e-2)" "unprognostic (5.30e-2)" "prognostic unfavourable (7.01e-5)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.05e-3)" 16.8 12.6 14.1 14.1 16.6 22.7 13.0 18.0 16.0 17.0 10.5 14.6 7.0 12.2 16.7 10.0 20.5 9.9 12.4 9.5 12.0 12.0 10.2 16.4 14.5 17.3 18.7 11.2 14.3 10.9 17.4 44.8 18.5 17.7 12.7 13.2 7.5 13.7 10.4 10.1 12.6 15.3 13.4 20.7 16.9 13.9 14.6 18.6 27.1 12.3 13.3 19.9 15.7 19.5 5.6 5.1 9.3 4.0 9.7 5.8 1.9 14.8 8.3 13.8 10.8 6.8 8.1 9.3 30.8 12.1 14.1 16.5 8.7 20.1 18.8 11.0 12.6 8.8 14.2 15.3 21.3 21.6 4.0 12.0 14.7 8.1 5.8 21.1 9.2 5.7 4.9 18.2 11.1 12.4 28.6 11.2 16.6 5.6 21.9 4.8 8.1 10.1 13.0 28.3 6.9 11.5 16.9 6.7 8.5 17.4 12.4 5.8 8.2 5.7 17.9 13.1 14.7 10.6 13.4 8.1 6.3 19.0 23.3 5.9 12.5 9.3 3.0 4.6 4.4 3.9 4.8 5.6 5.1 5.8 3.7 5.2 3.9 4.5 2.2 9.7 4.0 5.1 4.2 1.9 14.1 16.6 18.0 16.0 12.0 12.0 18.7 11.2 17.7 18.6 UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805207-49813946 "Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 22.3;HEL: 20.8;HMC-1: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol 1400000 "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: " "prognostic favourable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavourable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favourable (1.48e-4)" 11.3 12.1 6.8 22.0 7.5 16.0 11.5 2.0 6.7 10.8 12.7 14.4 25.4 19.6 17.2 31.6 17.7 12.9 33.1 9.1 6.7 3.9 15.9 11.9 18.8 28.2 6.0 6.2 19.1 9.5 1.4 8.4 8.9 9.4 18.5 12.1 14.2 24.5 34.2 3.3 9.0 25.5 11.3 7.7 35.9 13.2 3.4 5.9 20.4 17.8 18.4 23.5 12.6 13.1 12.4 14.3 24.8 21.7 11.1 11.8 13.0 4.3 0.0 0.3 0.1 12.0 12.7 1.3 2.3 10.4 16.7 22.3 0.0 9.1 0.1 1.8 8.5 2.4 0.0 4.1 1.4 11.1 0.0 20.8 0.2 1.3 8.9 1.9 40.6 19.5 0.2 6.5 0.4 8.3 0.0 1.3 3.8 0.1 4.2 5.1 0.0 0.4 5.4 0.4 0.7 3.4 8.4 0.0 0.3 2.8 4.1 1.4 0.4 13.8 3.7 3.3 0.4 1.4 0.9 0.0 0.0 0.1 9.1 7.4 0.7 13.9 14.7 24.8 11.8 21.7 10.3 12.3 10.8 10.5 14.3 12.4 9.9 8.9 4.6 11.1 17.2 5.2 10.6 13.0 6.8 7.5 2.0 6.7 6.7 3.9 6.0 6.2 9.4 5.9 UBE2A "HHR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574467-119591083 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (2.27e-3)" "prognostic favourable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 24.8 20.6 26.7 23.1 24.6 16.8 32.5 20.2 24.2 23.7 32.8 23.9 20.2 21.7 23.8 26.7 37.2 20.3 21.2 42.2 23.6 22.1 32.2 26.6 22.8 26.3 26.8 19.7 18.7 17.2 24.3 18.2 112.4 24.7 20.4 30.2 20.0 21.0 22.6 46.8 23.6 29.2 27.9 29.1 25.1 20.4 17.0 19.5 36.3 23.2 32.8 31.5 26.7 24.0 21.0 29.0 34.1 36.3 12.8 21.2 17.4 32.5 27.5 17.3 14.6 30.3 37.4 16.2 33.8 30.2 40.3 38.3 14.2 22.4 25.8 34.4 37.2 23.5 24.7 17.9 38.9 35.8 14.6 11.4 22.0 12.7 27.8 28.5 19.6 25.5 25.6 38.6 16.8 27.9 14.0 23.1 45.6 34.5 43.9 26.9 28.8 31.1 22.4 18.4 24.0 32.5 21.4 13.3 13.7 45.0 20.7 24.6 18.0 24.9 27.2 25.9 11.6 51.1 38.1 22.4 36.4 25.3 27.5 36.1 20.2 16.5 22.7 34.1 18.1 35.4 14.3 21.0 15.7 15.8 29.0 18.8 10.0 14.3 30.1 12.8 36.3 23.0 21.2 17.4 26.7 24.6 20.2 24.2 23.6 22.1 26.8 19.7 24.7 19.5 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371179-134391992 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 83.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 17.7 27.7 20.4 17.0 16.6 25.9 22.8 16.2 28.3 13.8 18.0 7.9 11.6 14.4 19.4 17.0 25.6 13.6 18.3 59.2 20.3 16.4 17.8 19.8 21.8 18.7 13.8 18.7 16.7 26.4 7.8 16.2 27.8 17.6 15.4 15.1 10.2 16.1 18.5 106.5 15.9 16.2 21.6 15.1 16.6 14.1 21.7 12.7 13.2 18.2 34.0 16.3 19.2 22.8 9.6 8.8 83.3 14.1 9.6 14.6 10.5 36.2 9.6 20.0 19.0 17.5 18.9 32.3 27.3 14.4 17.6 21.0 28.9 24.4 19.8 33.0 17.4 14.5 15.1 20.2 19.2 31.4 16.3 10.9 26.5 31.0 20.5 12.9 22.4 16.2 27.5 15.9 13.5 15.0 19.9 36.0 15.8 21.2 20.4 34.1 8.6 9.1 20.6 22.0 27.6 15.7 28.1 27.0 21.1 21.4 10.1 47.4 21.8 35.6 29.7 20.5 14.3 27.5 29.8 30.1 41.2 27.9 23.1 24.4 20.3 34.7 11.5 31.2 9.4 12.5 8.6 9.6 12.0 9.5 7.9 9.6 14.6 12.3 83.3 9.6 14.1 8.8 14.1 10.5 20.4 16.6 16.2 28.3 20.3 16.4 13.8 18.7 17.6 12.7 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 130.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: , HPA054975: " "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavourable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavourable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 3.1 2.3 0.4 24.0 0.9 25.1 4.3 0.4 0.7 3.8 9.5 0.4 0.8 7.8 2.0 2.6 25.6 0.6 3.2 2.8 0.5 0.4 2.1 2.1 4.6 15.6 0.6 0.5 1.2 1.3 0.0 0.6 12.6 0.9 1.3 11.7 0.7 3.7 0.6 1.0 8.3 10.0 3.5 1.2 11.6 7.0 15.3 0.5 130.8 0.8 17.6 26.3 2.8 7.8 1.2 0.9 2.7 0.6 2.4 10.0 4.2 39.2 28.8 52.0 24.9 1.4 3.2 29.9 31.2 15.8 51.4 36.9 94.6 45.4 41.6 30.6 14.8 38.8 0.2 33.4 52.5 17.7 27.4 12.8 22.1 24.8 0.4 18.3 32.2 1.0 3.6 34.8 34.1 25.0 0.2 35.4 42.3 64.6 30.2 5.2 31.2 69.0 32.1 47.1 0.2 17.3 13.6 30.0 25.0 49.1 36.0 19.7 36.3 27.0 9.1 46.1 40.3 31.3 60.3 11.2 0.3 46.4 28.0 13.1 43.7 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.2 2.3 0.9 0.2 0.2 0.1 2.7 2.4 0.6 0.5 10.0 4.2 0.4 0.9 0.4 0.7 0.5 0.4 0.6 0.5 0.9 0.5 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334975-58370753 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 41.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavourable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavourable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 8.2 10.6 8.1 10.0 7.9 17.1 7.5 7.7 9.0 6.3 7.3 5.5 4.8 4.7 8.5 5.5 8.2 5.5 6.4 25.6 7.6 7.2 5.5 5.4 7.0 13.7 8.1 6.7 5.9 4.8 5.3 7.4 6.8 7.4 6.5 7.9 3.5 6.4 5.0 74.9 4.6 5.8 8.8 8.4 11.0 5.6 3.2 8.4 5.5 6.0 25.1 7.1 9.5 10.0 3.7 7.2 41.0 13.7 2.8 3.5 7.1 10.6 5.8 10.8 13.9 22.2 17.9 7.0 7.0 12.0 8.1 11.9 11.7 9.2 0.0 11.1 10.5 9.7 20.9 10.2 11.4 11.0 12.3 2.8 2.1 6.7 14.6 8.4 6.8 20.7 11.5 8.4 15.7 16.1 5.5 4.5 10.9 3.3 9.0 9.4 13.2 9.1 7.6 9.8 5.9 12.1 6.2 8.2 11.0 13.8 23.3 11.2 8.5 5.7 12.9 3.1 10.9 10.6 7.7 11.5 8.9 9.4 9.8 17.5 3.5 2.8 13.7 6.2 2.4 9.5 2.8 3.3 2.9 3.0 7.2 3.7 3.0 2.3 41.0 2.8 7.9 3.0 3.5 7.1 8.1 7.9 7.7 9.0 7.6 7.2 8.1 6.7 7.4 8.4 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628433 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favourable (5.09e-5)" "prognostic favourable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavourable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavourable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 35.6 25.0 41.2 31.5 39.9 44.2 35.9 31.9 49.6 43.9 50.4 35.5 31.5 22.2 35.5 52.2 44.8 47.6 27.1 34.8 39.5 40.5 37.2 39.5 34.8 55.6 40.5 36.1 35.3 41.7 23.8 35.3 33.6 35.9 30.8 46.4 30.7 30.5 37.9 80.6 33.2 37.4 39.3 41.9 41.3 29.1 68.0 29.3 71.0 34.4 31.2 64.5 42.2 36.1 34.3 39.3 40.8 23.0 22.5 41.7 19.5 36.5 24.4 42.8 29.9 28.9 37.1 27.4 38.7 36.2 45.6 53.4 62.8 34.8 52.3 51.0 39.9 23.2 42.0 65.2 61.1 33.7 24.5 29.6 27.0 36.0 56.6 28.9 26.4 29.1 33.7 45.2 67.7 48.6 25.6 44.8 42.2 36.7 44.6 41.2 23.5 26.6 34.0 44.5 37.8 47.9 43.3 39.0 25.8 33.8 43.5 61.4 27.2 25.7 31.8 34.8 19.4 28.9 47.2 32.2 52.3 73.3 24.9 47.7 27.7 14.8 20.9 40.8 22.6 18.8 24.7 34.1 32.7 31.7 23.4 34.3 41.7 35.2 34.5 22.5 23.0 39.3 40.0 19.5 41.2 39.9 31.9 49.6 39.5 40.5 40.5 36.1 35.9 29.3 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favourable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 67.2 70.6 39.1 52.7 44.6 132.7 70.4 36.9 50.9 45.5 51.8 37.5 38.4 49.3 46.3 39.1 63.2 45.7 47.5 72.5 37.3 39.5 63.0 91.9 67.5 68.1 43.4 36.9 60.6 53.4 42.8 49.1 66.5 45.2 49.6 48.5 38.4 46.7 43.3 91.1 53.2 58.9 48.4 44.4 68.2 49.5 40.0 42.2 88.8 66.3 55.4 61.4 74.6 81.4 24.7 31.2 118.0 36.2 29.7 33.2 50.9 52.5 30.1 50.3 40.6 53.7 77.6 43.3 53.6 71.4 47.8 45.2 45.2 75.1 56.4 35.1 54.3 30.2 53.6 71.9 65.9 52.3 27.0 51.3 31.0 36.8 56.4 72.1 44.2 58.9 45.6 52.7 73.9 62.0 64.4 57.6 63.6 42.5 105.7 41.1 36.4 30.2 55.8 49.4 40.7 48.2 50.3 50.8 42.8 32.9 84.5 60.4 35.1 42.7 56.9 50.1 42.9 32.8 48.6 51.1 65.8 86.2 53.4 40.2 53.7 71.1 35.9 54.6 25.1 36.1 33.2 24.7 31.8 29.6 31.2 20.1 32.6 29.7 118.0 29.7 36.2 21.5 32.6 50.9 39.1 44.6 36.9 50.9 37.3 39.5 43.4 36.9 45.2 42.2 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926438-43956136 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.6" "Cell line enhanced" "Detected in all" "SH-SY5Y: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favourable (4.86e-4)" "prognostic favourable (5.77e-4)" "prognostic favourable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 10.1 13.1 14.7 5.0 13.3 4.5 9.1 13.8 17.4 8.8 7.6 11.4 7.9 5.3 7.5 11.2 8.0 9.0 7.2 23.8 14.2 10.0 12.7 15.3 8.4 5.3 12.1 9.4 7.9 17.4 8.7 6.9 5.9 11.9 8.7 6.2 8.1 10.6 9.1 48.6 9.4 5.3 10.3 12.8 7.3 6.5 5.1 6.1 2.7 9.6 16.1 5.7 7.7 6.5 10.7 11.8 12.9 20.5 7.7 14.0 6.7 3.7 3.2 1.9 8.9 9.2 3.7 1.5 1.9 4.6 2.4 3.1 1.7 4.5 3.7 5.2 4.9 4.3 2.5 2.0 3.6 8.1 4.1 3.9 4.9 4.3 3.4 8.5 8.0 2.9 4.3 2.7 4.1 2.9 4.3 7.6 3.2 2.4 5.0 4.9 4.3 4.1 3.1 2.7 5.6 5.0 4.6 7.3 24.7 3.9 7.9 2.9 3.9 2.6 2.5 1.6 4.9 3.3 5.4 11.0 8.2 1.8 4.7 11.2 8.7 6.3 11.7 12.9 9.3 18.4 9.5 10.3 11.6 10.5 11.8 10.7 14.0 11.5 1.1 7.7 20.5 10.2 9.4 6.7 14.7 13.3 13.8 17.4 14.2 10.0 12.1 9.4 11.9 6.1 UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805903-23891316 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030445, CAB073413" Approved Approved Nucleoplasm Nucleoplasm "CAB073413: , HPA030445: AB_10669599" "unprognostic (7.50e-2)" "unprognostic (2.78e-2)" "unprognostic (7.91e-3)" "unprognostic (7.13e-2)" "unprognostic (6.74e-3)" "unprognostic (1.74e-1)" "prognostic unfavourable (9.97e-7)" "unprognostic (3.69e-2)" "unprognostic (3.53e-2)" "unprognostic (1.34e-2)" "unprognostic (5.36e-3)" "unprognostic (2.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" 32.0 28.1 50.8 34.7 44.4 56.1 52.6 38.7 43.4 41.9 40.6 32.4 27.5 23.9 35.3 35.6 57.9 29.5 29.9 58.5 47.3 43.2 33.6 34.0 34.9 44.9 52.0 36.9 36.5 32.0 41.6 22.5 44.5 38.1 38.5 37.8 23.2 30.3 36.4 52.2 33.3 25.8 44.1 55.6 36.3 29.9 24.3 43.3 33.8 41.4 38.0 47.3 52.2 46.3 6.7 7.6 6.8 9.1 7.0 7.2 4.1 33.3 21.0 33.2 16.5 20.3 29.6 29.0 25.3 39.3 28.4 38.1 15.8 37.0 29.5 21.4 24.3 10.8 39.1 31.2 37.3 35.7 43.7 40.8 15.8 19.3 29.2 40.2 21.8 27.9 29.5 36.2 48.7 45.1 28.5 33.0 22.7 17.2 28.2 43.7 48.7 53.9 31.4 14.5 85.0 44.2 23.8 9.6 34.5 22.6 21.0 36.4 23.6 53.2 29.3 20.9 25.9 15.4 18.7 27.5 16.3 58.5 22.5 38.6 16.1 2.4 8.4 6.8 4.5 9.1 6.5 6.5 5.4 3.8 7.3 6.7 7.2 4.3 3.3 7.0 5.8 7.6 3.9 4.1 50.8 44.4 38.7 43.4 47.3 43.2 52.0 36.9 38.1 43.3 UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.2;intermediate monocyte: 17.8;memory B-cell: 12.3;myeloid DC: 20.9;naive B-cell: 14.8;non-classical monocyte: 18.3;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 6 "B-cells: 14.8;dendritic cells: 27.1;monocytes: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm Nucleoplasm "CAB073417: , HPA003303: AB_1858521, HPA028872: AB_10966277, HPA030445: AB_10669599" "unprognostic (2.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "unprognostic (3.68e-3)" "unprognostic (3.74e-2)" "unprognostic (1.70e-1)" "unprognostic (9.19e-3)" "unprognostic (3.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.20e-1)" "unprognostic (4.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.44e-2)" "unprognostic (2.68e-2)" "unprognostic (3.11e-2)" "unprognostic (6.11e-3)" 22.7 11.4 19.2 12.0 23.3 7.6 15.9 18.8 32.7 22.4 14.5 20.8 7.5 5.9 17.7 31.9 19.7 12.0 18.5 23.4 21.3 21.8 19.1 15.8 16.7 17.7 14.1 19.7 19.0 9.8 15.5 14.4 9.0 20.9 18.2 6.4 8.4 11.2 17.0 32.0 14.8 7.2 22.4 17.6 15.9 11.1 17.8 13.3 14.8 16.8 11.1 14.5 17.0 16.2 14.8 27.1 0.4 18.3 0.8 3.6 5.2 16.7 6.0 16.0 0.3 14.2 15.9 14.5 10.6 18.1 10.0 14.1 1.7 13.8 14.6 7.3 9.3 1.6 11.6 16.5 12.9 0.1 11.6 0.0 7.2 2.0 10.2 0.0 11.7 12.5 17.4 14.3 24.2 9.6 0.8 15.6 9.0 2.6 7.6 3.3 11.3 8.8 16.0 6.2 16.7 9.7 0.4 4.1 8.5 11.7 6.9 0.2 14.7 9.7 8.3 9.9 14.0 6.6 12.0 15.0 4.9 21.5 9.3 6.6 2.7 0.0 15.2 0.0 0.2 17.8 0.3 12.3 0.5 0.2 20.9 14.8 3.6 1.3 0.4 0.8 18.3 27.1 0.2 5.2 19.2 23.3 18.8 32.7 21.3 21.8 14.1 19.7 20.9 13.3 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavourable (8.08e-5)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavourable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 29.1 23.9 35.6 21.1 33.0 20.1 49.7 37.4 62.9 30.4 25.2 18.6 19.8 23.0 26.6 29.2 23.1 29.7 35.9 37.8 43.9 32.5 36.0 29.6 28.5 37.6 31.5 31.9 27.7 29.9 42.9 21.6 23.9 30.5 20.9 27.8 24.6 26.3 22.7 76.8 28.1 26.2 24.1 41.3 20.4 28.3 28.1 21.5 30.9 37.4 27.8 23.0 31.8 23.0 7.7 29.7 25.6 16.9 8.5 12.0 9.6 17.2 7.9 113.1 3.9 33.6 43.4 18.0 23.2 29.4 19.6 24.5 8.5 21.1 8.5 20.4 31.6 7.4 68.2 23.8 35.3 20.8 20.6 29.5 10.7 23.6 16.2 13.6 14.1 17.1 22.2 17.1 16.6 25.8 15.0 16.0 48.1 9.5 24.8 12.8 21.6 37.4 24.3 11.5 20.3 33.3 15.3 19.7 22.0 10.1 10.7 9.5 5.8 20.2 23.7 38.2 25.2 22.3 27.0 14.0 8.9 24.0 37.7 5.4 21.1 13.0 14.0 25.6 9.3 12.3 11.1 7.7 7.3 12.0 9.2 4.9 7.8 8.5 13.2 8.5 16.9 29.7 2.8 9.6 35.6 33.0 37.4 62.9 43.9 32.5 31.5 31.9 30.5 21.5 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037444 Approved Approved Cytosol Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavourable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 14.5 18.4 21.3 13.6 17.6 19.9 17.2 12.2 19.8 16.7 15.8 17.7 12.3 13.6 14.7 32.2 25.0 11.0 16.3 34.6 20.2 21.6 14.6 24.1 12.9 26.4 23.4 10.1 10.4 62.8 16.3 13.2 22.2 24.2 14.9 19.6 11.4 15.3 18.2 32.1 10.3 17.9 20.2 20.2 14.6 15.1 13.9 16.8 15.8 32.9 17.4 17.7 18.7 16.4 10.9 23.1 35.6 30.0 39.9 29.1 24.6 13.7 7.9 18.1 18.5 23.6 28.8 25.6 13.0 18.6 14.7 15.1 8.6 8.8 7.1 4.7 29.0 11.7 20.5 28.2 22.9 10.8 8.0 9.8 10.0 27.9 29.7 4.1 23.1 16.5 46.6 19.3 29.5 25.9 29.8 4.6 26.5 20.6 11.1 18.0 19.9 12.0 13.5 12.0 12.7 22.1 5.8 12.1 18.1 15.2 11.5 23.9 10.4 17.1 16.1 16.2 14.2 18.3 13.9 5.7 4.4 13.9 19.2 12.5 11.9 35.6 21.0 25.2 29.1 27.6 11.5 10.9 19.9 17.6 18.6 10.1 18.6 18.8 15.6 39.9 30.0 23.1 20.5 24.6 21.3 17.6 12.2 19.8 20.2 21.6 23.4 10.1 24.2 16.8 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA045681: , HPA050551: " "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 10.8 11.1 12.6 17.8 13.5 14.3 11.2 11.6 15.3 13.0 19.4 17.8 8.9 11.9 13.3 8.5 27.4 9.2 9.7 26.9 13.5 11.2 14.6 17.7 8.9 18.7 15.2 9.7 9.1 17.1 12.0 6.0 11.4 14.5 14.0 13.3 8.8 11.9 12.0 95.6 14.1 16.6 14.6 19.4 15.0 11.9 11.8 13.6 21.3 12.5 20.7 23.3 17.7 16.5 23.7 13.1 24.4 11.5 20.5 20.6 13.1 21.2 23.0 21.5 15.7 17.6 18.7 30.7 20.7 16.7 19.8 17.4 15.8 10.9 33.3 21.8 20.3 23.0 26.7 19.2 31.9 17.5 21.8 12.4 12.2 18.0 17.3 18.0 23.6 15.9 28.8 18.7 27.3 26.4 21.8 36.1 16.2 9.5 22.9 16.6 23.7 12.0 29.8 11.4 30.4 23.0 14.0 9.3 17.4 19.5 17.0 16.1 16.7 11.8 19.8 19.9 15.2 23.2 23.1 14.0 16.4 47.1 15.3 16.9 15.2 8.1 10.3 24.4 15.4 10.8 20.6 23.7 20.1 20.1 13.1 15.5 20.2 20.5 18.6 20.5 11.5 9.6 18.3 13.1 12.6 13.5 11.6 15.3 13.5 11.2 15.2 9.7 14.5 13.6 UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44802019 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved "HPA003332: AB_1858525" "unprognostic (7.58e-2)" "unprognostic (5.41e-2)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (6.30e-2)" "unprognostic (4.67e-2)" "unprognostic (5.99e-2)" "unprognostic (3.79e-3)" "unprognostic (6.93e-3)" "unprognostic (7.02e-2)" "unprognostic (1.40e-2)" "unprognostic (6.98e-3)" "prognostic unfavourable (7.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" 30.9 20.7 18.9 22.8 20.9 25.8 21.1 21.0 21.6 18.9 22.7 20.5 19.8 14.9 22.2 18.4 19.3 20.5 18.0 37.1 18.3 17.1 26.2 27.3 19.7 19.7 19.0 17.0 18.1 30.2 22.1 26.0 17.0 18.9 18.3 16.5 18.6 15.4 28.3 50.8 15.6 16.9 28.5 17.8 23.8 20.2 14.0 18.8 18.4 20.6 18.7 21.6 20.9 18.9 11.9 17.5 5.9 13.0 14.0 17.3 12.1 15.6 3.2 10.8 13.9 14.8 6.5 9.9 11.1 8.6 9.7 10.6 12.4 2.1 20.3 10.6 11.0 6.3 15.8 13.4 8.8 19.0 16.3 33.0 2.3 10.0 11.7 24.3 5.7 10.4 15.9 13.0 12.7 15.2 30.6 14.2 13.3 7.0 26.9 2.9 28.1 14.0 22.1 10.0 18.1 12.7 8.4 12.6 22.4 15.6 5.1 16.0 4.9 21.2 10.8 9.4 6.7 8.7 17.9 22.3 43.8 20.1 9.4 28.8 11.0 2.3 11.6 5.9 16.0 11.8 17.3 11.8 14.7 16.2 12.5 11.9 15.7 16.6 3.6 14.0 13.0 17.5 14.6 12.1 18.9 20.9 21.0 19.3 18.3 17.1 19.0 17.0 18.9 18.8 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952949 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Supported Mitochondria Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavourable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 29.0 49.9 31.1 16.6 31.0 22.5 24.5 36.1 30.2 31.1 27.3 33.2 26.6 15.2 35.5 25.3 32.1 29.4 26.6 61.0 26.4 25.4 27.6 28.1 26.3 17.5 28.1 23.4 27.6 52.3 41.8 29.5 37.9 33.3 24.1 16.8 22.9 28.5 28.8 46.3 21.3 16.5 31.5 26.2 19.1 22.7 24.7 29.5 24.7 37.7 23.6 29.5 25.5 34.3 6.1 3.7 7.8 2.2 1.3 6.5 1.9 22.7 12.3 14.6 14.8 36.4 31.3 25.3 21.1 27.2 12.9 14.4 6.6 24.4 9.4 26.4 20.7 17.3 12.5 22.4 16.9 11.6 6.6 3.2 18.1 7.9 28.6 6.5 10.4 42.0 29.8 17.4 28.0 25.1 7.7 27.4 19.9 8.1 8.6 7.1 23.0 14.7 6.7 7.5 20.1 27.0 29.9 5.6 16.9 19.3 43.2 11.3 4.5 6.4 25.5 14.1 7.1 19.8 20.9 25.0 18.0 15.6 28.0 7.8 13.7 3.5 2.2 5.1 4.7 1.7 6.4 3.8 4.7 4.2 2.0 6.1 6.0 6.4 7.8 1.3 2.1 3.7 6.5 1.9 31.1 31.0 36.1 30.2 26.4 25.4 28.1 23.4 33.3 29.5 UBE2I UBC9 ENSG00000103275 "Ubiquitin conjugating enzyme E2 I" P63279 16 1308880-1327018 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003909, CAB009021" Approved 120000 "CAB009021: AB_2210610, HPA003909: AB_1858529" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-2)" "unprognostic (3.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (2.88e-3)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (7.60e-3)" "unprognostic (3.56e-1)" "unprognostic (7.28e-2)" "unprognostic (9.30e-2)" "unprognostic (1.57e-1)" "prognostic favourable (5.68e-4)" "unprognostic (1.15e-3)" 34.3 43.1 28.8 36.3 36.9 48.4 45.2 45.6 48.5 38.1 32.0 28.6 28.1 28.9 55.4 32.9 43.4 35.6 30.3 41.8 27.4 28.4 29.4 26.6 29.1 44.2 22.7 32.9 62.5 35.5 33.4 36.2 47.2 21.4 40.7 31.0 34.1 37.8 32.2 31.6 35.8 32.2 40.0 23.2 43.7 29.4 43.6 21.6 78.0 42.5 31.8 53.9 38.7 38.8 82.2 58.0 85.4 67.4 50.9 57.8 60.0 24.9 34.5 58.2 34.3 25.0 30.3 25.2 36.0 26.0 33.5 33.5 40.8 41.1 43.5 30.0 31.1 30.5 41.6 33.8 43.3 31.3 29.4 27.2 31.9 39.4 39.6 40.3 32.5 28.0 22.0 32.8 39.3 36.2 38.9 27.4 31.6 53.3 71.2 40.6 47.4 25.5 90.4 36.9 49.5 31.2 23.0 33.0 34.8 31.6 35.9 35.9 36.5 48.9 29.8 33.3 38.2 29.2 32.5 29.0 34.3 88.8 18.7 30.0 35.2 63.9 59.3 85.4 48.0 67.4 57.8 82.2 49.0 48.7 58.0 61.8 44.1 44.2 41.3 50.9 62.3 50.1 50.9 60.0 28.8 36.9 45.6 48.5 27.4 28.4 22.7 32.9 21.4 21.6 UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352848 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.5;Karpas-707: 54.0;U-266/70: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced "CAB073419: , HPA003509: AB_1858531" "unprognostic (1.82e-1)" "unprognostic (3.20e-2)" "unprognostic (1.55e-3)" "prognostic favourable (2.87e-4)" "unprognostic (3.41e-1)" "unprognostic (7.93e-3)" "prognostic unfavourable (6.90e-5)" "unprognostic (1.19e-1)" "unprognostic (9.36e-2)" "prognostic favourable (7.43e-4)" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "prognostic unfavourable (1.11e-4)" "unprognostic (5.11e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (9.38e-2)" 18.7 17.3 14.6 47.1 15.4 52.7 28.2 19.1 13.6 18.8 25.9 11.3 24.4 28.0 19.5 18.4 19.2 18.0 19.9 17.1 14.4 14.7 18.7 33.5 20.4 52.0 17.0 9.5 17.2 46.1 11.5 13.6 27.5 13.0 22.9 26.3 10.7 42.1 33.2 12.5 11.3 36.3 17.9 18.9 45.8 24.4 17.7 14.4 42.5 17.6 16.4 47.7 21.7 21.4 20.7 23.7 15.9 17.8 6.4 6.4 6.1 8.1 2.8 7.9 10.1 8.3 10.8 0.0 13.0 11.5 8.1 8.9 4.6 5.1 62.5 7.3 13.4 3.3 5.1 7.5 13.2 8.7 8.0 11.3 3.7 7.6 22.1 14.2 7.4 8.2 7.6 6.7 11.6 18.0 9.1 54.0 9.4 5.0 5.9 10.9 2.7 4.1 23.3 10.2 29.9 10.1 5.7 4.0 8.1 5.5 12.2 12.0 4.8 31.6 12.0 4.5 4.3 8.0 9.9 60.7 30.1 17.1 8.9 10.3 7.4 10.3 6.6 12.3 3.4 11.1 4.0 20.7 4.6 4.2 6.5 13.4 4.3 3.9 15.9 6.4 17.8 23.7 6.4 6.1 14.6 15.4 19.1 13.6 14.4 14.7 17.0 9.5 13.0 14.4 UBE2J2 "NCUBE2, Ubc6p" ENSG00000160087 "Ubiquitin conjugating enzyme E2 J2" Q8N2K1 1 1253909-1273885 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.25e-1)" "unprognostic (3.04e-2)" "unprognostic (1.88e-2)" "unprognostic (4.46e-2)" "unprognostic (1.67e-3)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (9.57e-2)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic unfavourable (2.00e-4)" "unprognostic (2.09e-2)" "unprognostic (6.19e-2)" "unprognostic (1.87e-1)" "unprognostic (3.46e-2)" 24.4 22.2 17.5 21.6 17.1 19.4 33.0 23.8 24.9 17.8 22.0 17.9 19.9 22.0 22.9 21.4 25.2 21.8 20.7 21.2 17.5 17.1 21.6 27.3 17.4 27.4 15.9 15.4 19.4 36.3 14.4 22.8 22.6 15.9 16.9 16.2 18.7 24.2 20.2 29.8 23.2 23.6 19.3 13.1 25.2 22.2 68.3 12.8 26.1 22.8 21.7 23.8 18.3 19.3 24.5 22.3 39.6 23.0 22.0 25.3 17.7 25.2 10.5 15.0 14.4 12.2 12.5 11.7 19.6 15.5 26.8 19.6 18.7 18.5 13.6 20.9 18.0 18.5 15.2 19.5 21.3 23.1 27.3 20.5 20.6 16.8 23.7 18.8 19.7 11.7 10.9 21.0 15.6 18.8 28.3 13.5 15.5 12.6 27.2 21.1 16.2 26.4 25.4 14.0 22.5 13.9 8.6 55.5 27.4 13.5 29.1 30.9 14.9 21.4 15.3 16.2 15.6 18.7 20.0 29.9 29.0 38.1 20.9 29.9 12.8 38.2 23.0 39.6 22.0 22.2 20.1 24.5 23.4 22.8 22.3 21.7 21.2 20.9 32.6 22.0 21.3 20.8 25.3 17.7 17.5 17.1 23.8 24.9 17.5 17.1 15.9 15.4 15.9 12.8 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698044-39782792 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Supported "Intermediate filaments,Actin filaments,Cytosol" 150000 Cytosol "Intermediate filaments, Actin filaments" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavourable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 27.2 21.8 27.0 21.2 27.6 17.3 21.6 38.6 40.7 17.0 33.2 11.8 14.1 29.1 19.9 18.5 29.9 14.9 18.5 28.1 27.7 26.8 26.6 44.5 17.1 17.9 24.1 26.4 16.9 15.8 18.9 26.9 29.8 25.2 19.7 24.0 13.4 18.4 17.3 31.8 22.0 24.6 18.8 19.2 16.9 29.3 16.0 15.9 21.3 23.6 19.7 18.8 22.8 20.4 17.6 23.7 20.6 19.9 10.9 14.1 8.9 23.8 24.5 13.2 12.5 8.3 7.8 22.5 32.9 7.0 8.8 9.3 37.0 24.6 29.8 29.0 9.2 10.1 25.4 14.3 14.2 20.0 18.2 38.6 24.8 32.0 10.4 41.4 21.9 7.3 16.2 12.4 13.4 11.5 39.2 10.7 9.1 23.1 28.9 23.0 17.6 18.7 17.1 39.7 11.2 12.3 33.3 27.4 12.1 24.6 9.3 14.7 12.0 13.9 31.5 13.8 29.3 16.4 30.2 15.2 44.3 32.8 7.2 26.6 16.1 13.9 16.6 20.6 13.5 14.3 12.7 17.6 14.1 12.6 16.6 12.5 10.7 12.0 13.3 10.9 19.9 23.7 13.7 8.9 27.0 27.6 38.6 37.7 27.7 26.8 24.1 26.4 25.2 15.9 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol 8800000 "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: " "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavourable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favourable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 27.8 34.9 34.8 23.5 29.6 31.3 24.9 25.5 36.9 25.9 27.7 38.4 22.8 26.4 25.6 29.2 38.0 26.9 23.0 33.0 30.7 30.8 27.4 36.0 23.5 32.5 34.3 33.1 24.3 23.9 24.3 21.7 30.1 36.9 27.5 31.7 29.3 30.6 26.7 43.5 23.9 34.4 33.1 36.2 28.5 25.1 35.7 22.6 25.3 25.0 32.4 33.9 28.4 22.2 34.7 49.9 46.1 45.8 34.6 46.9 54.9 24.4 14.1 20.7 16.1 22.6 20.2 11.9 20.6 23.6 26.6 25.3 16.0 11.8 23.1 10.4 27.3 21.0 27.5 22.4 26.5 23.0 29.7 26.7 13.8 19.1 15.1 38.1 19.3 17.8 19.6 19.2 14.0 29.8 107.9 12.4 28.6 18.0 19.8 27.6 15.2 14.9 16.2 31.1 6.3 24.9 19.7 18.6 13.8 16.4 20.7 18.9 12.9 21.1 21.3 18.8 24.2 15.9 21.0 12.1 19.5 21.1 25.5 17.7 17.8 30.8 40.4 46.1 41.4 45.8 38.8 34.7 39.6 44.2 49.9 31.2 34.5 41.6 34.2 34.6 37.6 48.4 46.9 54.9 34.8 29.6 25.5 36.9 30.7 30.8 34.3 33.1 36.9 22.6 UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol 34000 Cytosol "CAB073407: , HPA003328: AB_1858539" "prognostic favourable (6.75e-4)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-2)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-3)" "prognostic unfavourable (4.88e-4)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (6.42e-2)" 31.1 31.0 32.0 34.1 28.6 30.4 40.4 18.2 25.6 23.3 19.1 17.0 17.1 19.0 21.9 30.0 19.9 28.6 27.4 18.4 23.5 27.4 28.3 55.1 50.5 45.0 28.9 20.4 27.1 21.8 17.9 18.5 21.7 25.8 26.0 18.8 18.7 42.8 22.2 10.1 15.9 23.5 28.3 23.6 47.9 21.4 7.7 23.6 44.0 33.6 15.1 34.4 33.0 49.0 49.2 53.6 113.6 83.4 61.2 66.4 112.6 8.7 4.4 14.9 4.7 31.6 39.4 1.6 5.1 30.4 45.1 58.7 1.6 22.8 28.0 18.0 15.5 7.0 6.4 16.8 9.6 25.5 0.2 27.6 0.0 6.2 58.6 6.3 9.1 42.1 3.9 21.1 5.8 14.2 1.2 19.4 8.1 11.1 42.5 15.2 3.9 5.6 37.6 9.1 19.2 12.1 9.8 0.3 7.8 10.2 0.8 22.3 11.2 3.2 5.2 9.4 3.3 7.1 1.6 26.5 26.7 0.5 26.3 16.0 2.0 56.7 71.6 62.5 51.2 83.4 56.4 49.2 53.4 53.4 53.6 39.7 46.5 48.8 113.6 61.2 68.3 34.0 66.4 112.6 32.0 28.6 18.2 25.6 23.5 27.4 28.9 20.4 25.8 23.6 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558960 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 18.1 26.0 51.8 16.3 38.9 32.1 13.6 28.4 52.4 15.2 20.4 17.0 20.5 17.8 17.3 19.6 24.9 19.3 17.4 43.2 35.1 33.9 19.6 19.1 16.5 18.1 32.1 30.5 19.4 20.2 25.9 22.8 32.0 26.4 18.4 16.7 15.0 20.9 22.6 61.9 19.2 15.9 19.2 19.8 18.5 17.9 31.8 16.1 32.7 22.2 21.2 19.9 18.2 23.5 3.8 7.6 10.9 4.3 1.8 3.8 2.1 21.1 38.6 19.6 18.6 10.5 12.5 14.3 22.1 19.5 16.0 13.8 23.3 16.5 22.3 16.7 15.6 13.9 21.7 21.8 12.0 25.3 131.9 32.4 24.8 15.1 25.6 29.3 25.7 13.3 17.1 24.4 29.0 19.2 15.7 28.2 21.2 21.7 23.3 26.6 12.4 33.8 21.8 16.3 28.6 18.4 26.7 34.4 28.2 19.1 23.4 20.6 14.1 26.9 14.4 50.2 10.2 15.7 39.1 34.1 51.6 23.9 31.9 26.0 32.7 6.8 4.3 4.1 3.5 2.8 2.7 3.4 3.8 3.7 3.1 3.8 3.7 2.5 10.9 1.8 2.7 7.6 3.1 2.1 51.8 38.9 28.4 52.4 35.1 33.9 32.1 30.5 26.4 16.1 UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93442262 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA044976 Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" 4600000 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: " "unprognostic (1.74e-2)" "unprognostic (5.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "prognostic unfavourable (2.41e-4)" "unprognostic (8.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.28e-3)" "unprognostic (1.07e-1)" "unprognostic (9.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (1.30e-3)" 24.7 25.0 29.0 28.7 39.1 29.0 21.2 29.2 44.3 18.4 26.6 15.6 15.1 20.7 23.2 20.0 30.4 19.7 17.0 27.7 31.0 33.7 25.4 22.3 19.3 36.1 27.6 34.5 17.4 17.6 13.9 18.2 24.2 34.9 23.4 22.6 13.7 18.0 18.5 35.7 19.1 20.4 21.3 24.6 21.5 19.3 83.7 17.4 32.2 15.5 16.8 35.1 22.7 18.8 53.8 35.5 29.9 39.2 29.5 57.3 51.9 35.8 26.0 43.9 28.1 17.0 16.9 30.6 50.2 26.8 40.3 33.8 46.2 15.6 73.0 11.4 29.3 28.6 48.4 36.8 38.4 60.7 25.1 49.1 14.3 40.7 21.7 58.6 32.8 17.7 15.2 24.0 30.0 31.0 54.5 11.4 41.8 29.5 57.8 54.5 57.1 36.4 45.0 35.6 35.7 33.5 54.3 42.9 39.1 26.5 31.2 24.5 40.8 36.1 32.0 27.3 22.8 24.6 36.1 19.7 53.3 62.0 10.7 31.3 33.3 29.9 27.1 28.9 31.7 35.4 36.9 53.8 40.2 39.2 35.5 38.6 36.0 34.4 8.2 29.5 39.2 26.7 57.3 51.9 29.0 39.1 29.2 44.3 31.0 33.7 27.6 34.5 34.9 17.4 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389451-76453206 "Enzymes, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" 1600000 Nucleoplasm "Nuclear bodies" "HPA023605: " "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavourable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 8.5 8.5 13.8 10.2 22.6 19.2 7.3 25.2 38.1 9.4 7.2 12.2 7.4 9.9 9.9 8.2 11.7 10.8 7.1 15.4 12.7 15.2 6.5 7.6 6.6 12.8 11.7 14.6 13.9 14.4 16.4 14.3 9.8 30.6 9.4 6.0 10.5 13.4 10.4 23.0 15.2 8.2 8.0 8.0 10.8 10.8 18.1 12.2 10.9 15.8 6.9 9.2 8.6 9.1 4.9 4.1 2.7 1.7 1.5 4.0 1.9 12.9 14.9 15.2 18.7 9.6 6.1 13.2 6.1 6.6 9.9 9.7 12.9 6.6 18.4 4.3 7.5 13.1 17.7 10.5 7.1 5.2 21.8 18.6 9.7 21.6 7.9 11.2 11.3 6.2 8.6 9.5 8.2 13.4 15.5 16.4 5.0 10.7 22.2 13.0 14.1 20.0 22.0 19.6 20.2 4.4 11.1 22.6 20.3 8.9 23.2 12.2 13.3 8.1 7.9 11.7 11.0 9.9 10.0 13.6 4.4 15.5 12.8 9.4 7.6 0.0 1.7 2.7 4.0 0.8 2.2 2.6 2.6 2.0 1.0 4.9 2.1 3.0 0.4 1.5 1.0 4.1 2.3 1.9 13.8 22.6 25.2 38.1 12.7 15.2 11.7 14.6 30.6 12.2 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome Nucleoplasm Centrosome "HPA063368: " "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavourable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavourable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favourable (1.86e-5)" "unprognostic (1.04e-2)" 17.3 18.7 26.5 16.2 29.4 24.2 19.4 26.4 29.0 20.0 21.2 18.7 8.2 16.2 18.3 25.4 20.9 21.8 18.2 17.6 24.5 25.8 25.7 27.4 23.0 26.3 22.8 21.0 21.7 27.2 21.4 29.3 24.5 27.2 21.4 25.7 18.5 19.0 19.8 19.1 21.6 21.4 21.9 19.1 26.0 20.5 30.0 22.0 25.1 21.0 14.0 29.9 19.3 18.5 3.2 5.1 8.1 3.1 4.7 6.2 1.6 18.0 15.7 22.2 16.9 22.8 23.6 19.2 17.9 27.4 23.2 18.8 17.6 19.4 22.3 25.9 25.0 15.8 26.1 20.8 20.0 22.4 16.5 17.7 14.0 17.0 28.8 28.7 28.5 22.7 27.6 18.7 21.7 29.7 14.8 27.7 29.5 28.0 17.5 21.1 30.3 26.7 20.2 15.5 23.4 25.4 19.3 22.6 31.6 18.2 34.3 29.4 20.9 43.8 20.6 15.0 16.8 17.7 19.1 33.8 25.0 29.5 16.8 20.3 22.7 8.1 2.8 5.6 4.8 3.1 4.3 3.0 4.5 5.9 2.5 3.2 5.0 5.7 4.4 4.7 2.6 5.1 6.2 1.6 26.5 29.4 26.4 29.0 24.5 25.8 22.8 21.0 27.2 22.0 UBE2Q2 DKFZp762C143 ENSG00000140367 "Ubiquitin conjugating enzyme E2 Q2" Q8WVN8 15 75843285-75901078 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "unprognostic (1.28e-1)" "unprognostic (1.66e-2)" "unprognostic (2.45e-2)" "unprognostic (4.28e-2)" "unprognostic (8.82e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-3)" "unprognostic (1.32e-1)" "unprognostic (6.38e-2)" "prognostic favourable (5.73e-4)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-3)" "unprognostic (1.01e-3)" "unprognostic (1.92e-1)" "unprognostic (1.69e-2)" "unprognostic (5.92e-2)" 17.8 19.8 15.6 18.8 10.9 22.2 41.1 11.6 14.4 20.0 25.2 12.4 12.9 6.0 17.6 15.5 24.7 11.8 22.7 25.1 15.0 16.0 16.5 6.3 21.0 25.9 19.8 10.3 17.2 13.8 7.7 12.6 34.8 12.0 22.3 13.5 13.0 20.1 15.0 26.4 11.0 11.1 42.9 23.1 15.1 14.7 13.5 11.6 27.6 21.4 22.3 11.2 40.2 35.7 6.1 4.2 18.0 6.9 10.6 9.6 4.8 9.6 14.8 13.8 9.8 19.3 25.5 20.7 21.4 24.2 14.2 16.3 7.7 13.3 9.6 15.9 30.8 7.9 24.7 14.1 17.5 9.9 10.0 12.0 9.0 10.4 21.3 12.6 7.0 17.7 16.4 10.0 14.8 19.6 4.5 14.5 30.2 7.4 10.2 11.6 9.7 10.7 12.2 21.7 3.8 22.6 15.4 12.0 9.4 18.4 17.3 23.3 11.1 17.2 26.0 17.7 16.2 11.8 7.5 15.8 27.7 7.6 7.1 19.3 10.7 18.0 4.7 15.5 7.2 5.3 9.0 6.1 9.6 7.6 4.2 4.8 7.7 6.4 0.7 10.6 6.9 1.5 6.1 4.8 15.6 10.9 11.6 14.4 15.0 16.0 19.8 10.3 12.0 11.6 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448623-6494909 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 28.1;heart muscle: 11.3;retina: 8.2;seminal vesicle: 8.6;skeletal muscle: 21.3" "Cell line enhanced" "Detected in some" "Karpas-707: 17.8;PC-3: 14.9;SCLC-21H: 13.9;U-266/70: 33.3;U-266/84: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "eosinophil: 1.2" "Lineage enhanced" "Detected in single" "granulocytes: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favourable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 0.6 2.3 8.6 0.8 4.2 0.3 0.9 20.7 28.1 1.0 1.8 1.0 0.5 0.7 1.4 1.8 1.0 0.5 0.8 11.3 12.6 8.2 2.6 1.1 0.4 0.7 5.2 4.6 3.6 0.8 0.3 1.3 0.3 8.7 3.1 0.8 8.2 1.0 8.6 21.3 2.4 1.0 1.3 1.4 0.4 2.2 0.9 0.0 0.0 1.9 2.0 0.5 0.5 0.9 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.8 0.0 3.0 0.0 0.0 0.2 14.9 0.1 0.0 6.6 0.0 0.0 13.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 33.3 29.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 4.2 20.7 19.4 12.6 8.2 5.2 4.6 8.7 0.0 UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817567-33920404 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 21.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061000 Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA061000: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavourable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" 26.1 19.7 29.4 19.7 26.8 13.9 39.3 23.7 32.3 25.6 24.1 27.9 16.3 28.0 26.1 18.4 25.3 22.3 21.8 29.2 25.5 20.3 22.1 34.5 23.0 27.1 30.5 23.2 29.8 44.5 15.7 13.9 24.6 21.6 21.0 21.4 19.3 18.7 20.8 56.1 28.1 25.7 28.5 24.2 21.6 20.8 34.5 29.6 36.7 19.5 22.5 25.7 35.8 30.5 3.3 4.2 21.9 11.6 5.0 2.1 2.4 16.3 18.0 34.6 15.0 19.1 31.2 10.6 14.6 20.3 17.1 17.1 14.4 12.3 14.0 6.0 20.3 7.3 18.1 16.6 18.8 23.0 9.6 12.0 19.8 18.3 27.2 14.3 13.1 26.4 24.7 14.0 26.5 28.7 11.3 15.1 16.9 9.5 26.9 37.6 19.7 14.9 25.0 10.5 7.2 18.1 12.4 16.2 19.5 17.0 15.2 10.9 13.4 17.4 21.4 16.5 15.0 11.4 13.5 9.6 9.0 19.5 15.8 8.3 35.5 12.4 7.5 4.1 2.0 7.5 1.3 3.1 1.9 1.6 4.2 3.3 1.9 1.7 21.9 5.0 11.6 2.6 2.1 2.4 29.4 26.8 23.7 32.3 25.5 20.3 30.5 23.2 21.6 29.6 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407777 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0;lymphoid tissue: 60.2;testis: 69.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: " "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavourable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavourable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 10.2 9.2 18.0 19.5 15.9 68.0 4.7 11.4 21.6 6.1 12.0 9.1 4.5 8.4 7.1 7.2 17.1 6.0 9.7 18.0 18.7 18.1 5.9 5.6 6.3 22.9 13.7 14.4 6.4 6.0 3.7 12.9 9.8 12.9 7.0 7.1 6.2 4.9 5.3 7.3 6.2 7.3 10.7 15.3 11.0 10.6 69.4 8.2 60.2 5.9 14.3 21.1 10.0 7.1 4.5 3.1 6.0 1.9 0.6 2.6 0.3 59.4 32.2 28.3 22.6 1.8 2.6 5.0 48.4 14.7 29.9 27.3 21.8 21.3 57.9 20.1 12.1 17.5 28.4 12.6 13.3 45.3 94.2 34.6 18.5 7.0 5.4 41.3 33.7 2.8 3.5 22.0 21.3 11.7 34.3 40.6 18.7 15.7 56.0 21.5 71.1 54.7 49.3 21.8 20.8 8.0 12.7 72.0 39.0 61.7 15.3 27.4 10.9 22.5 17.9 18.1 51.3 15.3 115.2 32.7 78.5 67.9 18.9 29.3 65.3 1.1 1.9 2.9 1.8 1.5 1.2 4.5 2.6 2.6 1.5 1.6 2.5 1.5 6.0 0.6 0.9 3.1 1.0 0.3 18.0 15.9 11.4 21.6 18.7 18.1 13.7 14.4 12.9 8.2 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavourable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favourable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavourable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 1.9 4.2 9.6 8.5 12.2 20.8 3.9 4.4 13.5 3.5 11.2 0.7 17.2 7.5 4.3 4.1 10.3 2.9 3.0 8.8 8.8 11.2 4.5 2.8 3.1 15.2 8.7 8.2 1.3 0.9 2.4 3.1 8.7 8.2 2.2 13.9 1.9 2.8 7.0 13.1 4.5 6.9 8.1 3.4 6.7 4.0 16.0 1.8 46.8 2.6 12.8 15.3 6.3 4.5 9.0 3.6 1.7 8.6 1.1 11.1 2.9 30.3 29.0 43.2 20.4 4.0 7.4 24.7 33.2 18.6 38.0 26.8 20.6 37.3 35.4 13.2 12.1 24.8 39.9 19.5 34.3 32.1 22.8 21.6 15.8 23.5 1.8 25.9 26.4 2.6 4.7 29.9 12.4 22.0 27.3 29.3 29.7 28.3 46.3 33.0 16.7 14.8 35.9 46.0 30.8 14.5 14.6 34.0 34.7 23.2 28.6 11.1 30.1 16.4 10.8 17.1 27.4 29.9 39.4 14.9 29.0 45.1 17.0 27.0 35.5 0.0 0.8 1.7 3.7 2.4 2.8 9.0 5.0 3.9 1.7 6.3 7.3 8.0 0.0 1.1 8.6 3.6 11.1 2.9 9.6 12.2 4.4 13.5 8.8 11.2 8.7 8.2 8.2 1.8 UBE2U MGC35130 ENSG00000177414 "Ubiquitin conjugating enzyme E2 U (putative)" Q5VVX9 1 64203627-64267368 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 31.8" "Cell line enhanced" "Detected in some" "EFO-21: 2.3;U-266/84: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 19.5" "unprognostic (9.44e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (4.01e-2)" "unprognostic (3.63e-1)" "unprognostic (7.69e-2)" 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli Nucleoli "HPA045161: AB_10960706, HPA073181: " "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" 15.2 14.2 13.5 13.3 21.8 17.5 13.4 18.9 24.4 12.0 9.8 11.3 11.0 7.9 13.4 10.5 16.6 9.4 15.2 14.8 19.0 12.3 21.9 23.4 13.6 11.6 11.6 13.0 11.8 12.7 18.4 20.9 13.6 18.4 12.0 11.5 9.5 12.2 10.6 16.4 10.6 8.5 12.8 12.6 13.6 10.0 16.4 12.3 14.7 17.1 4.8 12.9 16.8 12.8 5.0 8.1 23.0 9.4 4.7 4.3 4.8 8.5 5.6 6.9 7.5 12.1 12.4 6.0 9.4 10.4 9.1 9.5 4.6 9.6 4.0 7.8 9.8 8.7 10.2 9.6 15.2 6.4 6.2 8.1 5.8 7.1 8.2 4.4 11.5 9.7 10.8 10.6 19.0 11.0 4.0 8.6 13.8 6.8 9.6 4.8 5.3 11.1 2.9 7.1 3.4 16.9 9.4 5.1 5.6 7.5 24.5 11.3 11.5 7.9 9.8 11.0 8.4 8.3 6.9 7.3 7.5 2.9 9.6 7.1 9.4 12.9 9.4 11.5 3.5 8.8 4.3 5.0 3.6 2.6 6.3 4.3 3.2 3.8 23.0 4.7 9.4 8.1 4.0 4.8 13.5 21.8 18.9 24.4 19.0 12.3 11.6 13.0 18.4 12.3 UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908369-48929056 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007922: AB_1858551" "unprognostic (6.85e-2)" "unprognostic (5.72e-3)" "prognostic favourable (4.62e-4)" "unprognostic (9.11e-2)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (2.32e-2)" "unprognostic (5.26e-2)" "unprognostic (8.66e-2)" "unprognostic (9.17e-3)" "unprognostic (3.48e-2)" "prognostic unfavourable (1.05e-4)" "unprognostic (2.63e-2)" "unprognostic (2.11e-2)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" 27.1 40.6 29.2 27.7 37.0 22.2 28.8 34.4 50.2 33.7 28.9 59.9 45.1 26.6 36.2 49.5 37.2 36.0 28.0 28.7 30.5 29.2 32.1 25.6 29.2 30.9 46.6 28.0 32.5 29.5 36.6 28.0 35.0 39.7 32.9 32.5 28.4 33.3 43.2 24.1 35.9 30.5 39.1 32.7 36.6 29.4 22.4 43.4 29.4 39.8 22.2 44.2 28.8 32.2 12.8 10.1 11.0 14.5 7.4 13.1 8.6 24.8 30.9 11.6 11.0 29.5 28.7 15.9 27.3 33.5 32.7 31.6 38.5 21.6 20.3 39.2 33.4 16.2 14.5 25.5 41.8 67.1 15.8 18.3 20.4 23.9 34.2 13.0 19.8 24.4 28.3 26.6 34.6 23.9 13.4 26.5 35.1 39.8 14.0 12.9 10.8 27.0 11.3 29.6 11.5 25.6 24.5 12.0 18.2 18.5 10.0 18.6 27.6 10.3 28.1 49.0 23.7 16.0 22.2 20.2 19.2 12.0 24.0 9.5 21.2 6.5 11.0 8.1 13.1 14.5 10.7 9.4 11.4 13.0 8.0 12.8 11.1 12.0 11.0 7.4 13.0 10.1 11.5 8.6 29.2 37.0 34.4 50.2 30.5 29.2 46.6 28.0 39.7 43.4 UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" 19.3 19.4 20.3 23.1 25.0 17.8 20.2 30.0 25.1 21.7 19.9 14.3 19.8 14.1 21.0 22.1 19.8 18.5 17.2 24.0 22.2 20.8 20.2 24.6 19.7 23.1 19.1 19.5 23.0 17.2 26.1 24.6 20.1 20.9 20.6 17.9 13.3 19.3 21.5 70.2 18.4 18.8 21.2 19.9 18.8 16.9 26.4 16.4 36.4 25.0 26.6 19.5 19.9 26.6 15.6 11.9 11.6 14.8 21.1 16.0 5.7 19.3 10.9 27.6 16.4 16.1 19.2 13.6 29.8 18.7 21.1 19.2 25.3 9.7 34.7 22.6 22.2 17.9 34.9 21.0 25.8 17.9 11.7 28.8 18.4 14.9 24.2 34.7 21.3 22.6 19.8 19.9 25.5 16.5 29.0 24.8 33.1 10.5 28.7 10.1 17.9 15.9 29.5 41.2 15.3 19.1 30.4 28.3 21.4 24.1 26.2 34.2 21.4 19.6 21.2 37.0 30.6 17.7 21.7 28.4 33.5 46.8 21.2 18.9 19.2 8.6 8.7 11.6 13.3 7.6 15.2 12.0 14.0 15.9 11.9 15.6 16.0 14.2 2.0 21.1 14.8 11.1 10.1 5.7 20.3 25.0 30.0 25.1 22.2 20.8 19.1 19.5 20.9 16.4 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favourable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 14.5 19.3 17.2 12.9 21.2 9.2 15.3 19.7 27.8 14.4 17.3 23.3 14.0 14.6 17.4 16.2 20.1 19.3 13.9 28.6 14.6 11.6 19.8 16.4 15.5 13.1 18.6 13.9 18.4 20.3 25.5 15.1 16.8 15.8 17.5 21.2 20.7 15.7 17.4 34.0 21.6 16.3 18.6 15.2 17.0 17.3 24.5 18.3 18.2 21.1 17.6 15.9 19.5 19.6 15.9 14.5 22.4 16.7 14.3 18.2 11.4 10.4 16.6 13.0 9.4 22.2 17.9 11.4 13.8 15.9 16.8 11.3 17.3 10.8 6.5 10.3 22.6 13.5 13.2 17.7 16.3 14.3 9.3 12.5 10.8 15.6 14.3 10.1 10.5 20.3 16.6 16.3 19.6 18.1 13.6 6.2 19.1 16.4 6.9 14.8 13.3 20.0 11.5 12.3 12.8 14.4 18.9 12.1 22.4 16.1 22.0 10.8 22.4 10.8 16.5 20.9 6.0 10.6 9.8 13.9 11.5 11.5 20.8 8.5 17.3 22.4 15.3 14.3 15.9 16.7 15.7 15.9 15.3 11.2 14.5 12.9 12.9 17.1 19.5 14.3 13.6 13.5 18.2 11.4 17.2 21.2 19.7 27.8 14.6 11.6 18.6 13.9 15.8 18.3 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138913-157269372 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" Mitochondria "Nucleoplasm, Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favourable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 24.7 21.0 14.0 17.9 23.1 12.4 19.8 25.5 29.9 21.3 23.4 17.2 15.3 17.4 28.8 16.8 26.8 18.8 24.8 31.8 14.4 13.8 21.2 30.5 16.7 16.7 14.5 15.1 20.7 22.1 29.6 20.3 21.3 22.3 19.0 21.0 20.2 31.7 21.5 51.2 21.2 23.9 25.7 16.1 20.5 21.8 35.9 11.1 20.3 15.6 24.5 24.4 23.1 19.1 2.5 4.0 2.1 4.6 3.7 6.6 2.9 22.5 17.9 11.5 23.0 20.7 21.8 12.8 25.0 21.6 21.1 21.4 16.1 18.9 12.2 22.3 27.5 14.4 17.9 23.1 25.2 22.2 16.4 12.4 12.6 11.6 20.7 18.6 18.3 19.3 21.3 23.4 19.5 24.6 18.1 13.7 29.8 19.7 18.2 11.8 18.3 21.7 10.5 13.0 25.1 21.9 24.9 18.5 19.1 24.6 21.2 18.3 10.9 13.1 22.0 26.7 5.7 65.4 31.0 13.7 13.8 12.3 30.6 27.8 30.5 0.5 3.5 2.1 4.8 4.6 6.6 2.5 5.2 5.2 4.0 2.5 4.9 5.9 1.3 3.7 4.5 3.6 5.2 2.9 14.0 23.1 25.5 29.9 14.4 13.8 14.5 15.1 22.3 11.1 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359585-118399211 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA055035: , HPA064010: " "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 19.3 18.5 17.7 20.5 30.1 16.6 19.7 49.4 36.6 19.0 18.5 33.0 16.1 20.3 23.2 21.2 21.2 19.8 17.0 20.3 17.7 18.8 20.3 29.5 18.4 22.2 25.7 25.7 24.2 26.7 31.1 24.2 18.6 35.5 21.5 23.1 21.2 20.3 17.2 32.5 25.6 23.7 19.9 25.5 24.0 25.5 21.8 27.5 22.1 22.1 15.1 22.6 21.6 20.4 5.7 11.0 14.6 13.2 7.1 9.0 5.2 9.1 8.9 11.4 11.4 19.8 18.4 11.4 13.6 14.2 10.1 12.4 24.5 22.6 19.3 26.3 17.0 20.3 16.1 12.8 16.8 10.8 7.5 31.6 8.0 12.6 17.1 17.8 24.3 18.5 9.3 20.6 20.3 16.8 17.9 18.2 14.5 17.3 15.2 17.8 10.6 11.4 9.7 16.6 19.7 11.1 21.4 10.4 10.8 19.6 17.0 6.0 22.7 8.2 17.2 15.0 9.9 12.8 11.2 5.4 6.5 18.4 8.3 20.7 15.3 14.6 10.9 10.5 9.0 12.0 6.9 5.7 6.9 6.4 11.0 4.3 7.4 6.6 11.0 7.1 13.2 6.5 7.7 5.2 17.7 30.1 49.4 36.6 17.7 18.8 25.7 25.7 35.5 27.5 UBE4B "E4, KIAA0684, UBOX3, UFD2" ENSG00000130939 "Ubiquitination factor E4B" O95155 1 10032832-10181239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019219 Approved "HPA019219: AB_1858554" "unprognostic (5.32e-2)" "unprognostic (1.56e-1)" "unprognostic (3.74e-2)" "unprognostic (5.46e-2)" "unprognostic (7.19e-2)" "unprognostic (4.39e-2)" "prognostic unfavourable (3.69e-5)" "unprognostic (2.53e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-1)" "unprognostic (4.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-3)" "unprognostic (2.99e-1)" "unprognostic (3.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" 11.8 18.6 16.4 11.5 20.2 16.5 12.7 27.1 24.2 17.5 19.3 26.5 12.6 15.1 16.7 12.8 20.4 14.1 11.3 22.5 18.9 17.3 13.0 13.9 10.5 11.3 18.5 15.0 22.8 20.4 24.3 15.3 18.3 23.6 14.5 12.8 18.2 12.0 12.7 43.5 24.3 14.5 16.6 16.3 13.0 15.1 8.6 21.4 15.7 19.7 11.2 13.6 16.8 12.0 6.0 6.7 9.4 7.9 2.9 9.8 5.3 21.6 13.9 17.1 18.8 22.7 30.0 13.5 14.3 18.1 14.0 14.4 15.0 25.4 18.7 17.4 25.4 16.0 21.4 16.5 16.7 19.1 12.0 20.1 24.3 17.6 17.2 21.0 14.3 24.7 15.0 18.9 16.1 20.6 34.5 24.9 13.0 11.3 13.5 10.3 22.8 11.5 13.3 17.0 20.1 14.2 9.9 20.9 16.1 22.5 16.1 29.7 12.3 15.5 17.8 12.6 19.4 15.5 11.6 11.4 15.4 21.6 18.5 24.4 15.9 4.2 7.9 3.6 5.3 6.0 8.8 6.0 8.8 8.5 6.7 5.6 8.0 6.5 9.4 2.9 4.4 3.2 9.8 5.3 16.4 20.2 27.1 24.2 18.9 17.3 18.5 15.0 23.6 21.4 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263081-159286040 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavourable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 17.1 16.0 16.7 18.4 19.7 16.7 16.3 20.2 33.0 18.5 12.5 12.2 11.4 9.8 22.5 13.1 22.2 14.7 14.5 13.1 20.9 19.1 17.5 14.4 17.8 24.1 19.7 22.7 16.8 12.6 18.0 23.9 19.6 36.7 14.7 14.7 10.9 15.4 17.6 15.3 14.2 13.8 19.5 20.4 22.2 13.3 24.2 15.4 26.8 14.4 16.1 30.1 18.8 16.8 11.9 10.8 21.9 13.9 25.5 19.2 8.2 14.5 10.6 22.0 23.8 22.9 21.2 13.0 15.9 24.2 16.3 21.8 8.6 10.1 13.0 17.6 19.8 11.1 13.6 30.5 28.5 25.9 13.3 10.0 9.3 7.8 28.9 22.6 15.8 18.7 28.7 14.8 29.6 15.5 13.7 17.6 22.7 4.7 12.2 6.9 15.2 6.4 15.5 21.5 15.2 16.1 11.2 11.7 15.5 16.0 10.7 37.4 11.3 15.1 16.5 16.8 14.1 8.7 20.0 14.1 14.2 19.8 17.8 15.6 24.9 21.9 6.5 16.1 16.6 13.5 18.6 11.9 15.8 17.3 8.5 10.9 18.5 19.2 19.4 25.5 13.9 10.8 16.9 8.2 16.7 19.7 20.2 33.0 20.9 19.1 19.7 22.7 36.7 15.4 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038838 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA038838: AB_10673120" "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 16.7 13.2 13.7 18.3 16.7 28.4 18.8 21.8 18.1 18.2 16.2 14.8 10.5 11.3 21.0 12.9 10.8 15.9 14.2 19.7 10.0 15.4 14.4 10.6 16.6 14.9 11.8 10.5 16.3 16.4 26.3 25.6 16.2 18.9 15.3 12.9 12.5 11.8 16.8 23.6 11.0 14.4 18.2 12.1 14.7 13.8 13.7 14.7 23.2 18.8 9.7 14.3 17.3 19.7 4.6 5.0 5.5 4.2 6.2 7.2 1.8 4.9 7.2 8.3 6.7 13.2 10.2 7.9 12.1 13.4 10.7 13.9 9.1 3.9 5.8 7.2 12.4 8.6 11.9 10.6 12.8 11.9 5.8 22.9 14.4 4.4 9.2 16.1 11.0 11.0 6.0 13.1 10.7 12.0 13.0 8.8 13.3 2.8 8.7 4.8 4.7 7.4 11.4 11.4 5.0 10.8 11.7 8.4 7.5 15.9 8.4 5.6 8.1 8.4 16.5 13.2 8.2 11.7 12.2 10.4 17.6 16.7 9.0 10.2 11.9 4.4 3.0 5.2 5.7 4.2 6.5 4.1 5.9 6.9 2.9 4.6 5.9 7.2 5.5 6.2 3.4 5.0 4.1 1.8 13.7 16.7 21.8 18.1 10.0 15.4 11.8 10.5 18.9 14.7 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564062-42693504 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 25.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favourable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 19.8 18.8 14.4 21.8 16.7 22.1 18.6 26.6 20.4 17.2 19.3 17.8 17.8 20.1 29.5 16.8 16.2 15.6 16.2 16.8 13.8 13.2 17.8 24.0 19.3 18.0 16.7 12.9 20.8 24.6 28.0 26.3 16.3 17.2 16.5 20.1 15.8 18.3 15.6 33.5 18.0 24.6 19.9 15.9 21.3 18.2 9.2 17.2 26.1 20.1 14.9 17.7 18.9 29.8 3.6 3.5 25.2 5.7 3.9 4.4 1.9 15.7 8.0 9.3 14.6 19.2 18.5 12.6 12.2 13.2 10.8 11.3 11.5 6.5 10.9 9.7 13.1 16.0 13.4 10.4 13.8 14.6 9.4 17.2 11.9 14.9 15.6 16.6 11.9 13.0 11.4 10.7 11.8 12.2 20.1 13.8 10.4 12.8 13.0 14.7 8.5 7.8 11.6 13.9 16.2 12.4 13.8 11.1 8.8 12.3 11.9 11.9 11.6 16.1 17.6 9.9 7.7 12.0 8.8 12.8 11.3 16.8 5.2 12.5 6.0 10.4 4.6 9.2 4.4 4.8 3.7 3.4 2.9 3.4 3.5 3.6 3.0 3.3 25.2 3.9 5.7 2.6 3.3 1.9 14.4 16.7 26.6 20.4 13.8 13.2 16.7 12.9 17.2 17.2 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3 (putative)" Q6ZT12 2 169827458-170084131 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 11.9 15.5 10.9 6.1 18.3 5.4 9.6 15.5 18.9 9.9 10.0 9.8 9.1 6.7 11.5 7.1 10.7 8.1 7.8 23.1 10.3 7.2 12.9 16.9 9.2 5.6 11.9 14.0 8.9 9.8 20.9 14.9 7.2 14.7 11.2 7.3 8.0 11.1 9.2 76.3 11.5 8.4 9.6 10.2 6.9 9.2 7.9 11.4 6.3 14.9 10.9 6.0 12.8 8.7 2.0 2.8 1.9 2.1 2.4 4.3 1.2 8.8 7.5 8.0 10.6 16.0 12.7 6.8 16.0 9.3 9.3 7.5 11.5 5.6 10.0 13.9 12.4 11.7 9.5 8.1 11.6 10.4 8.2 36.6 8.0 12.2 8.0 12.1 11.9 7.6 7.6 12.1 8.1 9.1 19.0 10.9 15.7 8.3 7.8 5.9 6.3 6.3 7.5 13.2 10.6 6.7 12.5 15.8 8.6 11.2 10.4 6.5 6.8 6.8 11.5 14.0 5.7 10.9 10.0 8.9 6.9 9.2 11.5 7.1 7.7 0.0 2.1 1.7 3.2 1.8 4.2 2.0 1.9 2.7 2.8 1.2 3.3 4.3 1.9 2.4 1.6 2.4 3.1 1.2 10.9 18.3 15.5 18.6 10.3 7.2 11.9 14.0 14.7 11.4 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074506-19210276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 24.4 25.4 22.4 29.0 25.4 58.3 23.7 28.5 32.5 22.4 28.5 26.3 31.5 18.2 34.0 32.5 22.7 20.3 27.3 20.5 23.3 15.9 25.5 29.7 31.2 20.3 21.0 20.9 35.5 21.0 40.9 31.4 28.4 25.0 30.7 20.5 30.6 24.7 27.1 55.9 69.0 25.5 39.3 20.2 26.5 30.2 41.1 21.6 37.7 26.1 17.3 25.9 43.4 29.0 4.6 9.1 18.3 18.5 2.7 3.4 4.6 22.9 23.2 21.0 15.5 39.3 20.3 18.2 17.9 18.9 19.5 17.8 37.0 19.8 13.9 16.8 23.6 15.7 16.4 17.8 18.3 11.5 14.5 31.7 22.4 24.1 27.7 19.4 21.1 18.1 22.9 39.7 38.3 21.3 21.6 12.9 18.5 16.4 9.1 23.7 17.0 13.1 12.8 16.4 11.6 17.6 13.5 14.9 14.8 21.2 12.2 15.2 8.4 15.3 33.0 22.9 14.3 27.1 20.0 15.3 9.2 16.1 15.7 30.0 19.4 18.3 18.5 2.9 3.4 3.8 2.9 4.6 3.0 1.9 9.1 2.9 2.7 2.5 9.8 2.7 1.3 4.3 2.1 4.6 22.4 25.4 28.5 32.5 23.3 15.9 21.0 20.9 25.0 21.6 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102253012-102412841 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA053688: " "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 27.0 16.7 27.1 29.5 31.7 30.3 29.2 40.8 32.8 24.9 25.0 19.1 21.1 14.4 26.8 24.0 23.8 22.0 17.6 22.7 25.5 15.3 17.9 17.0 24.2 29.6 21.9 20.6 29.7 22.2 32.4 25.5 25.0 23.6 20.2 17.1 19.7 22.9 21.8 39.9 29.7 22.4 29.3 17.5 21.9 21.1 39.7 28.3 37.9 20.3 15.9 27.0 27.5 28.6 5.0 4.0 6.3 5.5 2.4 7.1 2.1 23.2 10.4 20.2 10.3 19.9 20.3 18.6 17.6 15.6 13.8 12.1 10.4 15.7 46.4 15.2 16.5 14.2 17.2 15.3 19.4 20.0 8.4 38.7 14.2 18.7 17.7 12.0 21.4 23.2 15.3 14.2 24.8 16.5 18.6 26.4 13.5 21.0 30.5 14.4 15.2 11.8 17.8 11.9 22.0 12.6 22.9 14.9 12.4 12.3 12.0 12.2 19.2 12.8 16.5 14.7 17.2 13.2 12.2 14.1 13.6 47.7 14.6 18.8 11.9 3.1 3.4 5.0 5.6 3.4 5.6 5.0 6.0 5.9 4.0 3.9 4.8 7.1 6.3 2.4 5.5 3.6 7.1 2.1 27.1 31.7 40.8 32.8 25.5 15.3 21.9 20.6 23.6 28.3 UBR7 C14orf130 ENSG00000012963 "Ubiquitin protein ligase E3 component n-recognin 7 (putative)" Q8N806 14 93207056-93229215 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000861 Approved Approved Nucleoplasm Nucleoplasm "HPA000861: AB_1078321" "unprognostic (9.60e-2)" "unprognostic (5.12e-3)" "unprognostic (1.11e-1)" "unprognostic (9.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "prognostic unfavourable (8.12e-5)" "unprognostic (1.14e-1)" "unprognostic (9.83e-2)" "unprognostic (1.04e-2)" "unprognostic (4.30e-2)" "unprognostic (5.94e-2)" "prognostic favourable (9.76e-5)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" 14.1 12.3 16.4 12.5 22.9 17.0 17.5 20.0 25.8 17.1 15.7 17.7 11.3 11.1 14.9 13.4 14.8 13.7 11.9 19.0 14.2 12.8 15.3 13.2 11.9 18.0 14.0 17.1 17.0 20.4 28.2 11.5 11.4 13.3 13.9 17.1 13.6 13.7 14.9 19.9 15.2 12.7 14.1 16.9 13.8 14.1 21.1 14.3 31.9 15.4 12.9 23.3 13.4 13.3 18.1 10.7 15.8 9.5 11.5 16.5 8.2 6.4 8.7 13.3 11.1 6.3 6.7 4.7 13.7 9.7 15.2 11.6 6.3 7.4 15.4 11.5 6.9 7.8 14.3 7.7 15.7 11.9 7.7 11.1 9.3 6.0 2.9 16.2 12.5 4.0 5.4 8.4 5.3 8.5 10.3 15.5 14.5 18.9 26.3 8.9 6.1 15.7 20.3 23.9 8.4 5.1 10.6 16.8 12.0 9.8 8.2 4.0 14.9 11.2 6.5 11.2 6.1 9.6 14.1 17.9 27.4 15.8 9.8 12.6 9.5 15.8 7.3 11.8 12.7 9.1 13.3 18.1 11.4 11.7 7.8 14.8 10.0 10.6 11.5 11.5 9.5 10.7 16.5 8.2 16.4 22.9 20.0 25.8 14.2 12.8 14.0 17.1 13.3 14.3 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760248-233773299 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 48.6;liver: 120.3" "Cell line enhanced" "Detected in some" "CACO-2: 4.2;HaCaT: 11.0;PC-3: 5.0;RT4: 26.1" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 4.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.2 35.6 0.1 0.1 48.6 0.1 0.1 4.3 0.0 0.3 0.1 0.1 0.0 4.5 120.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.4 0.1 0.7 0.1 0.1 0.9 48.2 0.5 0.1 0.1 1.3 0.2 0.1 0.1 0.2 0.1 0.1 5.2 0.8 1.0 0.4 4.7 0.4 1.1 0.5 0.2 0.2 0.8 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.0 0.0 4.2 0.3 0.1 2.0 0.0 11.0 0.0 0.2 0.0 0.2 0.1 0.1 0.4 1.1 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.2 0.4 5.0 0.1 0.1 0.4 0.0 26.1 0.2 0.3 2.0 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.6 0.3 0.2 2.1 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.3 0.1 1.0 0.4 0.5 4.7 1.1 0.4 0.4 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 9.4;gallbladder: 8.4;intestine: 31.1;stomach 1: 12.4" "Cell line enriched" "Detected in single" 142 "RT4: 106.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavourable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.3 0.0 0.3 2.6 0.3 0.0 0.3 0.3 0.3 0.3 19.2 0.3 0.3 31.1 0.3 0.3 9.4 0.1 8.4 0.3 0.3 0.0 0.3 1.4 0.6 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 14.3 0.3 0.9 0.3 0.3 0.3 20.2 0.5 0.3 0.3 12.4 1.0 0.3 0.3 0.3 0.3 1.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 40.6" "Cell line enriched" "Detected in some" 9 "HaCaT: 16.4" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718778-233773299 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "liver: 99.4" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;HL-60: 1.3;RH-30: 2.2" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A5 UGT1E ENSG00000240224 "UDP glucuronosyltransferase family 1 member A5" P35504 2 233712992-233773299 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 3.7;intestine: 13.9" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;RT4: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.18e-3)" "unprognostic (1.36e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 11.2 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 9.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 111.7;liver: 50.1;urinary bladder: 32.7" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;EFO-21: 20.8;HaCaT: 74.4;RT4: 37.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009819, HPA054065" Enhanced "CAB009819: AB_2241481, HPA054065: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.8 0.5 0.2 0.5 2.0 0.3 0.9 13.0 0.0 1.1 0.1 0.1 0.0 111.7 50.1 1.9 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.3 0.1 3.3 0.4 0.1 1.3 1.2 0.1 3.8 1.2 2.3 0.1 0.1 8.1 0.2 0.1 0.5 0.2 5.6 8.7 32.7 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.4 0.0 20.8 0.0 74.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 37.6 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "esophagus: 54.4;lymphoid tissue: 40.2;tongue: 23.6" "Cell line enriched" "Detected in some" 14 "SiHa: 49.4" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.0 0.1 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 40.2 0.2 2.8 0.2 0.1 1.6 0.2 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 49.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.6 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 13.0;urinary bladder: 15.7" "Cell line enriched" "Detected in single" 58 "RT4: 51.2" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.3 0.0 0.0 0.0 0.0 0.0 3.3 5.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671853-233773300 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 169.8" "Group enriched" "Detected in some" 20 "A549: 4.8;RT4: 3.9" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavourable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.8 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" Q9Y4X1 4 69588417-69653249 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 10.6;liver: 14.5;pituitary gland: 21.2" "Cell line enhanced" "Detected in some" "ASC diff: 3.1;HUVEC TERT2: 1.9;U-266/70: 3.5" "Cancer enhanced" "Detected in some" "liver cancer: 0.7" "Region enriched" "Detected in single" 17 "pons and medulla: 1.7" "Cell type enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "HPA017261, HPA045108" Uncertain "HPA017261: AB_10963582, HPA045108: " "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 14.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.7 0.0 0.0 1.5 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 2.0 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.2 1.7 0.5 0.4 0.2 0.2 0.1 0.1 0.4 0.2 0.1 0.3 0.2 0.1 2.0 0.9 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951791 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 150.5;kidney: 43.2" "Cell line enriched" "Detected in some" 9 "Hep G2: 20.5" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "eosinophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" HPA045108 Supported "HPA045108: " "prognostic favourable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favourable (6.07e-7)" "unprognostic (2.10e-2)" 0.1 0.1 0.1 4.3 0.1 0.0 0.7 0.1 0.1 0.1 63.8 0.1 0.1 31.9 0.1 1.7 0.1 0.1 14.6 0.3 0.1 0.1 43.2 9.6 0.1 0.1 0.1 0.1 0.1 12.0 0.0 0.1 0.1 0.1 0.1 8.6 0.1 0.1 0.1 0.1 0.1 150.5 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815993-68831196 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 277 "liver: 120.4" "Cell line enriched" "Detected in single" 39 "Hep G2: 15.8" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 120.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214731 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "breast: 77.4" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;HL-60: 3.0;NB-4: 2.4;RPTEC TERT1: 3.6;U-2197: 1.4" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "basophil: 6.8;eosinophil: 5.6" "Lineage enriched" "Detected in single" 68 "granulocytes: 6.8" HPA045108 Uncertain "HPA045108: " "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 77.4 0.1 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.0 3.3 0.1 0.1 0.0 1.2 7.3 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 7.0 0.1 0.1 1.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 3.6 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.6 0.0 0.0 6.8 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646630-68670628 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 22.4;intestine: 50.7;liver: 65.4" "Cell line enhanced" "Detected in some" "A549: 3.2;HL-60: 2.1;RH-30: 1.2;RPMI-8226: 1.1" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.7" "Lineage enhanced" "Detected in single" "B-cells: 2.7" HPA045108 Approved "HPA045108: " "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favourable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favourable (4.50e-4)" 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 48.0 0.1 0.1 5.4 0.1 0.1 0.2 0.0 22.4 0.1 0.1 0.0 0.1 65.4 0.1 0.1 0.1 0.1 0.1 5.3 0.0 0.1 0.1 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.0 50.7 0.1 0.1 0.1 5.7 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 1.1 0.0 0.2 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.4 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 68.1;liver: 21.6" "Group enriched" "Detected in some" 7 "BEWO: 3.1;NB-4: 3.5;RPMI-8226: 5.1;SH-SY5Y: 2.3;U-2197: 2.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "memory B-cell: 3.3;naive B-cell: 11.9" "Lineage enriched" "Detected in single" 59 "B-cells: 11.9" HPA045108 Supported "HPA045108: " "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.4 0.1 0.4 4.7 0.4 0.0 0.4 0.4 0.4 0.4 55.6 0.4 0.4 54.1 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.1 0.4 21.6 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 20.7 0.4 0.4 0.4 0.4 0.1 68.1 1.1 0.4 0.4 0.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 11.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.4 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280499-69295050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 71.7;salivary gland: 25.6" "Group enriched" "Detected in some" 10 "Daudi: 6.9;NB-4: 6.3" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 4.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 4.0" HPA045108 Uncertain "Intracellular and membrane" "HPA045108: " "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 71.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 25.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.2 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 105 "liver: 175.1" "Cell line enriched" "Detected in some" 9 "RH-30: 10.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" "CAB033260: AB_2241496, HPA045108: " "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 175.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 125.4;liver: 156.0" "Group enriched" "Detected in some" 5 "EFO-21: 20.5;RPTEC TERT1: 81.6" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favourable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favourable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favourable (5.38e-4)" 0.1 0.1 0.1 0.2 0.1 0.0 0.4 0.1 0.1 3.1 7.9 0.1 2.5 6.4 0.6 4.7 0.1 4.7 1.5 0.1 0.1 0.1 125.4 156.0 0.2 0.1 0.1 0.1 0.6 14.7 0.0 0.1 0.2 0.1 0.3 0.4 0.2 1.0 2.7 0.3 0.2 27.7 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 81.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951010-36001028 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 44.0;liver: 47.7" "Cell line enriched" "Detected in single" 42 "RH-30: 24.7" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA047697: , HPA056290: " "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 5.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 44.0 47.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 3.2 0.1 6.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.2 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035017-36071358 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 37.0;skin 1: 14.4;testis: 13.2" "Cell line enhanced" "Detected in some" "HDLM-2: 5.2;MOLT-4: 9.3;REH: 21.8;T-47d: 5.7;THP-1: 12.9" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Region enhanced" "Detected in single" "pons and medulla: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: " "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.1 1.1 0.1 0.0 0.2 6.4 1.6 0.1 0.6 0.1 0.1 0.5 0.4 0.0 0.1 0.8 0.1 0.1 0.2 0.2 0.1 0.6 5.6 0.8 0.1 0.0 0.5 0.0 0.2 0.0 0.0 1.7 0.2 2.0 0.6 0.0 2.9 0.1 0.0 0.1 14.4 0.1 0.0 0.3 1.4 0.1 13.2 0.0 37.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.4 5.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 4.0 0.0 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.6 0.1 0.6 0.5 0.0 2.0 0.0 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529629 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071190 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA071190: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 21.6 22.0 23.5 18.9 26.2 30.1 23.5 10.8 30.5 14.3 16.3 17.2 30.8 16.3 11.5 12.9 16.0 12.9 12.1 11.4 27.0 31.8 27.9 32.4 16.9 24.3 30.6 20.3 12.1 11.8 25.0 12.5 16.5 33.4 14.7 17.4 14.1 15.9 22.9 30.6 11.5 21.8 9.6 20.5 21.3 16.8 10.4 14.1 23.0 17.1 11.7 24.1 16.1 12.8 5.7 4.3 4.5 9.2 5.9 8.5 4.0 20.8 9.8 5.1 12.5 14.7 11.6 11.6 27.7 15.1 22.7 16.3 6.3 13.1 17.1 24.2 20.6 12.1 9.8 15.2 36.6 23.4 7.1 16.9 12.2 5.7 11.3 24.6 19.8 11.9 16.2 22.3 21.4 13.0 14.7 23.8 38.9 8.8 13.0 6.5 6.8 13.3 8.4 22.9 14.2 15.1 21.6 9.3 8.6 24.4 22.7 17.8 19.6 27.6 20.2 26.0 14.7 17.9 38.5 24.7 34.2 20.2 21.6 12.1 23.4 4.5 3.3 3.7 8.2 8.6 8.5 5.4 6.2 6.8 3.6 5.7 6.3 7.1 2.0 5.9 9.2 4.3 4.9 4.0 23.5 26.2 10.8 30.5 27.0 31.8 30.6 20.3 33.4 14.1 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 75.6" "Cell line enhanced" "Detected in many" "MOLT-4: 62.6;REH: 142.1" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.2" "Group enriched" "Detected in many" 4 "dendritic cells: 8.2;T-cells: 4.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavourable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavourable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 8.2 3.7 16.5 0.7 0.3 4.2 0.3 1.5 1.6 0.0 2.1 0.3 0.2 2.0 0.0 1.0 0.9 1.2 0.1 0.1 0.3 10.0 4.3 0.7 0.3 0.6 0.0 0.0 1.0 1.4 0.0 1.4 0.0 0.0 0.0 0.3 1.9 2.2 0.8 0.7 2.2 1.9 3.1 4.0 75.6 0.0 4.0 6.6 1.1 0.0 0.4 8.2 1.5 0.4 0.9 4.2 0.9 15.6 11.3 17.2 12.2 0.5 2.0 2.7 12.7 6.1 13.3 12.9 13.5 7.9 8.9 3.1 5.6 7.8 11.8 6.9 9.4 14.4 13.4 7.7 10.6 14.4 0.2 18.9 11.7 0.9 0.5 7.2 1.8 3.9 11.0 10.3 7.9 12.2 62.6 11.6 7.7 12.3 142.1 38.3 6.5 3.6 11.5 12.7 10.1 10.0 5.5 1.7 9.9 18.1 4.9 14.1 11.5 18.2 15.3 4.4 4.5 26.2 8.1 18.4 17.9 0.6 0.4 0.2 1.1 0.1 0.1 0.3 1.5 1.9 2.2 0.4 0.4 1.5 1.5 0.9 0.3 8.2 4.2 0.9 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm Nucleoplasm "HPA026633: AB_1858610, HPA026697: AB_1858611" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 14.1 12.9 10.6 25.4 12.2 49.1 19.0 24.8 11.8 18.6 15.6 12.7 17.6 7.9 17.5 15.1 13.3 12.0 11.9 11.3 10.2 10.6 10.1 9.8 13.5 19.3 12.3 10.5 18.9 14.5 12.7 12.7 14.6 11.4 19.3 12.0 10.7 13.0 16.4 15.7 11.0 12.0 17.1 12.2 14.1 11.6 10.6 14.8 40.3 15.2 10.2 19.8 18.7 18.2 5.1 2.5 7.5 1.4 1.2 3.6 1.2 6.6 7.5 10.9 4.6 9.0 12.9 8.0 15.3 9.4 9.6 16.9 4.8 4.8 10.2 3.3 7.6 4.3 10.0 8.9 14.8 18.3 4.7 17.7 14.7 7.6 7.4 8.2 6.0 5.8 5.8 7.5 18.4 37.5 1.7 9.9 22.7 2.3 13.8 32.1 4.2 5.6 15.8 5.0 3.6 7.2 4.6 9.9 3.8 6.6 4.4 9.6 5.5 16.6 31.7 10.3 3.8 4.3 12.8 2.6 7.9 11.9 5.0 7.2 4.1 7.5 1.1 4.3 2.3 0.9 1.7 3.5 3.6 1.8 0.7 5.1 2.3 3.0 1.3 1.2 1.4 2.5 3.5 1.2 10.6 12.2 24.8 11.8 10.2 10.6 12.3 10.5 11.4 14.8 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894651-131923167 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9;plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol Cytosol "HPA063990: " "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 10.9 18.6 14.6 9.2 49.6 33.2 8.9 24.0 24.4 14.4 11.8 6.9 13.3 11.7 16.5 10.7 9.8 10.6 16.2 17.4 11.5 8.3 9.0 15.8 9.0 8.3 7.9 12.0 18.2 59.6 13.8 23.8 17.2 11.6 13.4 4.0 13.9 18.1 13.4 33.4 24.3 11.5 10.2 5.4 16.5 11.4 11.4 11.4 13.8 10.7 9.6 6.5 12.1 10.9 0.6 6.4 6.9 1.7 0.2 0.8 0.6 5.1 16.6 7.7 9.6 3.5 2.8 10.5 8.2 5.9 3.5 2.8 3.6 5.3 1.4 8.6 5.7 5.1 1.7 3.2 1.0 5.5 10.0 3.4 13.6 4.8 6.5 2.5 7.6 5.2 9.0 3.9 1.6 4.3 4.5 4.1 2.3 11.7 15.3 14.5 8.5 15.9 11.6 2.8 6.8 2.0 6.4 19.6 10.8 8.7 9.0 4.5 13.7 16.8 8.2 8.4 5.0 14.6 3.7 18.3 6.6 1.8 14.2 4.3 9.6 0.2 1.7 2.3 0.8 0.7 0.2 0.1 0.7 0.7 0.3 0.6 0.5 0.5 6.9 0.2 0.7 6.4 0.5 0.6 14.6 49.6 24.0 24.4 11.5 8.3 7.9 12.0 11.6 11.4 ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9;non-classical monocyte: 5.8" "Lineage enriched" "Detected in many" 4 "monocytes: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved "CAB037021: AB_1841237" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.11e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-2)" 10.3 7.1 15.5 4.4 19.1 2.8 7.6 15.5 21.8 9.3 7.2 28.3 6.7 3.1 9.5 8.4 6.8 11.5 7.7 8.3 15.0 10.9 7.0 3.7 8.8 4.6 15.8 12.0 12.4 7.5 14.2 4.2 8.5 15.9 9.0 4.8 8.5 5.3 11.0 13.5 7.8 3.6 9.9 28.3 7.1 5.5 33.0 14.6 2.0 7.0 1.4 3.8 7.7 6.3 0.1 1.4 0.5 6.9 0.4 1.6 0.6 8.6 8.9 12.8 1.8 7.5 14.2 0.0 7.2 8.9 7.5 7.1 0.1 1.8 0.0 3.8 9.2 4.1 0.0 1.4 7.1 7.1 9.3 0.2 3.8 0.0 9.8 0.0 4.4 9.2 11.2 3.8 3.2 5.2 0.0 0.0 6.3 2.4 0.0 0.4 1.9 2.3 0.5 0.0 0.0 5.4 3.8 3.2 13.3 11.3 1.4 4.0 8.8 3.3 8.3 0.0 1.1 2.8 4.3 0.0 0.0 0.0 1.1 0.0 2.6 0.0 1.5 0.3 0.6 6.9 0.2 0.1 1.0 1.0 1.4 0.1 1.6 1.0 0.5 0.4 5.8 0.1 0.2 0.6 15.5 19.1 15.5 21.8 15.0 10.9 15.8 12.0 15.9 14.6 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836116-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved "HPA040474: " "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favourable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.0 11.7 11.8 8.4 15.4 2.9 7.4 21.3 20.4 7.9 13.8 9.0 9.0 7.9 5.3 9.5 33.9 6.7 9.6 14.1 11.8 8.9 13.4 9.3 6.4 7.9 11.2 15.3 4.9 14.7 12.1 12.3 5.7 21.1 8.2 14.4 10.4 10.4 7.4 19.1 24.6 20.3 7.2 5.8 9.9 11.1 6.0 7.6 4.2 6.1 10.9 13.7 8.6 10.6 3.8 4.2 3.8 7.8 5.8 12.6 4.9 3.8 10.5 5.5 9.5 6.3 4.1 3.6 3.1 4.5 6.4 7.0 4.1 8.8 8.3 5.9 3.4 3.9 15.4 4.3 2.7 16.0 15.2 24.9 13.5 5.0 9.2 5.9 15.9 5.5 8.5 5.6 5.3 9.7 6.9 9.1 5.2 5.8 4.3 6.1 6.2 5.4 12.8 6.7 15.9 4.1 4.9 10.3 13.0 6.0 5.7 19.0 8.3 14.9 5.4 8.6 5.5 8.4 6.6 12.6 11.4 6.1 4.8 17.4 7.4 3.8 3.6 1.4 12.6 7.8 10.1 3.8 7.4 10.3 4.0 3.5 8.1 5.5 0.9 5.8 6.2 4.2 9.7 4.9 11.8 15.4 21.3 20.4 11.8 8.9 11.2 15.3 21.1 7.6 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 4.3 4.8 5.1 4.7 8.3 10.3 4.2 4.3 5.4 11.9 2.8 5.9 6.0 2.1 10.7 10.9 2.8 12.3 3.1 13.1 5.2 3.0 5.4 3.4 5.5 4.2 3.1 4.2 4.5 3.6 13.5 19.7 9.0 5.8 4.4 2.8 6.7 4.2 4.5 1.4 3.5 3.3 5.1 5.7 4.4 3.4 27.5 3.4 6.3 7.1 1.7 8.4 4.0 6.0 6.4 5.1 10.7 6.3 2.6 10.3 5.2 7.2 1.7 2.6 3.0 1.1 1.7 4.5 2.5 2.6 3.0 2.6 0.9 2.1 8.4 1.4 5.7 3.7 3.2 1.9 2.8 1.1 0.9 1.6 5.3 2.8 3.9 5.5 1.7 1.6 2.2 14.7 3.0 2.1 1.8 7.0 2.2 5.8 6.9 4.4 3.2 3.0 1.5 8.4 3.7 6.4 7.0 1.3 9.7 2.5 1.2 2.0 2.9 1.8 6.1 1.9 2.2 13.0 2.0 4.2 7.9 3.5 10.8 5.8 2.3 5.7 5.8 5.8 8.0 6.3 6.5 5.6 8.6 7.2 5.1 6.4 6.5 9.2 10.7 2.6 3.2 4.6 10.3 5.2 5.1 8.3 4.3 5.4 5.2 3.0 3.1 4.2 5.8 3.4 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm Nucleoplasm "HPA028387: , HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavourable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 11.6 9.0 11.3 17.2 10.7 29.3 15.9 20.6 14.2 19.2 13.3 7.8 8.0 10.8 15.1 12.0 15.6 13.8 8.9 9.0 11.5 9.6 11.8 9.3 11.7 19.2 14.2 9.6 26.7 12.7 14.8 18.4 13.6 10.9 14.8 13.9 7.6 12.7 13.5 11.7 12.3 13.3 15.8 15.5 18.1 11.6 31.6 11.8 70.6 15.0 13.3 20.1 16.5 16.5 14.7 11.8 23.4 12.4 15.5 16.3 9.2 22.0 6.5 27.4 14.8 6.2 7.4 15.2 21.2 14.5 26.4 29.0 11.0 10.8 39.9 15.4 11.9 12.8 22.5 14.6 37.0 19.9 16.2 32.7 22.6 11.5 6.7 35.0 16.5 3.9 9.6 23.9 18.0 12.4 23.7 34.9 18.6 9.8 35.9 13.5 24.1 13.5 34.1 46.5 24.7 9.9 16.5 28.4 15.9 24.0 19.6 23.2 11.2 21.4 8.6 20.4 22.2 29.8 29.7 13.9 19.3 45.8 13.8 28.0 18.2 17.4 9.5 23.4 12.6 9.6 16.3 14.7 15.0 12.7 11.4 10.7 14.3 11.9 16.9 15.5 12.4 11.8 13.6 9.2 11.3 10.7 20.6 14.2 11.5 9.6 14.2 9.6 10.9 11.8 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699978-84779922 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 105.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 105.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favourable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 13.9 18.8 16.0 24.2 19.0 13.4 14.4 24.4 20.4 15.9 18.1 15.6 8.4 16.1 20.2 10.4 19.7 18.2 12.0 16.4 19.3 15.1 16.4 20.7 13.7 18.8 19.7 17.4 18.5 17.1 35.8 15.0 23.5 16.2 15.0 15.6 17.9 15.3 17.8 47.0 17.0 17.5 20.2 16.3 16.0 15.0 15.5 16.2 20.4 17.6 15.7 20.9 19.7 15.8 7.2 10.4 105.5 8.6 7.7 17.3 10.0 13.6 18.9 18.4 22.8 6.8 11.6 24.9 13.5 14.3 22.9 12.6 26.6 11.9 23.7 15.7 14.1 15.7 25.5 21.5 30.5 9.6 13.4 13.6 8.9 17.6 9.0 20.2 8.3 7.3 16.6 23.9 27.7 17.5 37.1 5.2 15.8 28.6 20.9 9.8 22.1 12.8 27.2 10.1 11.2 14.4 11.1 17.2 10.1 32.3 10.5 9.1 24.1 12.9 12.8 15.9 12.7 8.0 12.8 8.7 12.1 60.1 10.3 13.0 16.3 2.5 8.6 1.6 5.7 7.0 6.8 7.2 17.3 6.3 10.4 6.7 9.9 6.0 105.5 7.7 6.3 3.5 6.1 10.0 16.0 19.0 24.4 20.4 19.3 15.1 19.7 17.4 16.2 16.2 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232690-47248328 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavourable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favourable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 11.5 17.3 32.9 11.5 55.0 4.9 9.4 35.7 74.0 17.5 9.1 19.9 5.8 6.0 22.6 12.7 9.7 26.6 12.8 20.6 27.0 44.0 13.6 6.7 12.5 13.8 23.1 47.4 38.2 13.8 28.4 32.3 12.6 27.8 15.7 7.6 17.9 9.3 21.3 13.7 7.8 7.3 19.1 17.0 13.5 9.1 19.2 14.6 19.0 27.2 4.3 14.3 11.0 9.8 21.0 20.6 22.8 8.7 19.8 31.7 16.4 14.3 22.6 38.9 26.5 14.7 9.9 10.8 11.0 17.3 21.9 24.5 21.5 11.8 9.5 8.7 19.8 17.1 31.5 7.7 19.5 14.7 23.9 11.1 17.9 19.1 17.1 12.4 23.2 14.2 3.2 23.1 9.9 8.7 8.3 1.3 17.0 21.8 24.1 13.3 28.9 20.2 27.2 38.1 7.9 10.7 19.8 22.0 37.8 20.1 4.1 11.9 8.5 7.2 9.1 18.5 19.5 26.0 12.5 17.7 11.1 16.6 11.4 15.5 16.4 22.8 3.5 7.4 22.6 7.4 19.9 20.1 10.2 22.1 4.6 21.0 15.4 31.7 2.2 19.8 8.7 20.6 12.7 16.4 32.9 55.0 35.7 74.0 27.0 44.0 23.1 47.4 27.8 14.6 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066142-27171896 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 15.7 10.4 18.3 23.3 17.8 46.0 15.6 16.6 18.3 12.1 30.6 16.1 8.8 13.0 15.3 11.6 23.5 9.5 14.5 11.3 19.3 15.9 18.3 27.9 19.9 19.6 20.5 7.5 12.0 13.4 10.7 16.2 14.8 12.4 17.5 19.1 10.1 8.9 9.5 9.8 17.3 33.0 43.8 18.5 16.5 14.7 11.0 13.1 8.4 12.0 6.6 18.5 42.8 24.2 4.6 3.0 5.3 2.1 2.3 3.6 1.2 12.0 7.6 14.6 7.5 9.8 12.5 5.2 17.0 12.0 9.5 7.1 13.7 19.0 17.2 8.6 13.4 7.5 9.5 9.9 20.3 27.7 8.2 26.6 9.9 9.6 12.3 15.3 18.7 7.8 14.5 10.7 12.3 21.8 8.8 8.4 19.6 7.0 9.4 20.5 10.4 13.5 10.8 18.6 4.0 18.7 8.6 16.1 9.7 14.6 12.3 13.8 5.8 15.0 25.7 9.9 9.6 21.2 15.4 6.4 7.1 12.3 16.7 9.2 11.0 0.0 1.2 5.3 1.5 1.3 2.5 3.2 2.4 2.0 1.6 4.6 1.6 1.7 1.2 2.3 2.1 3.0 3.6 1.2 18.3 17.8 16.6 15.5 19.3 15.9 20.5 7.5 12.4 13.1 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179652755-179789401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.8;skeletal muscle: 90.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "MAIT T-cell: 15.4" "Lineage enriched" "Detected in many" 8 "T-cells: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavourable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (3.06e-4)" 6.4 7.5 2.0 2.3 2.8 0.8 3.5 2.9 4.1 2.7 2.1 4.6 1.5 0.7 3.2 3.8 2.6 2.5 2.5 34.8 2.0 2.3 2.3 3.4 6.0 2.5 2.1 2.1 7.2 3.0 3.3 9.8 1.9 3.0 3.0 1.8 3.1 3.3 2.1 90.3 1.8 1.7 3.7 2.5 1.6 1.6 5.6 1.3 1.7 5.5 17.1 3.2 2.6 1.9 2.0 1.9 0.0 0.4 0.0 15.4 0.7 12.3 5.3 10.1 7.7 4.6 6.4 4.9 7.3 8.4 10.8 9.1 7.8 4.4 15.3 8.2 8.8 0.9 11.3 4.4 12.9 36.2 4.8 4.0 8.0 7.3 3.3 11.2 0.0 6.8 1.6 8.4 10.7 8.6 1.9 19.8 8.9 8.1 6.8 2.0 7.8 4.8 11.7 10.0 12.5 7.3 3.5 5.7 7.4 7.0 9.4 4.2 16.2 8.1 9.3 13.0 10.4 11.1 28.1 9.6 8.0 31.4 6.0 7.6 12.1 0.0 0.2 0.0 1.3 0.4 15.4 2.0 1.3 2.9 1.5 0.6 1.0 1.0 0.0 0.0 0.4 1.9 0.6 0.7 2.0 2.8 2.9 4.1 2.0 2.3 2.1 2.1 3.0 1.3 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported Cytosol 1400000 Cytosol "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavourable (7.81e-5)" "prognostic unfavourable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favourable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 24.8 24.2 25.9 20.7 32.1 19.4 21.7 21.7 28.4 16.5 17.1 17.9 19.1 13.4 19.4 24.3 25.3 14.7 14.4 23.3 22.1 27.6 23.2 24.4 15.8 21.9 22.6 28.8 16.2 16.2 22.3 18.0 25.1 29.2 29.9 19.4 14.5 16.7 20.5 53.3 15.7 12.9 23.9 22.1 15.4 15.6 17.2 16.5 19.5 20.1 25.4 28.6 17.8 17.8 13.1 15.2 7.7 15.2 23.0 21.2 11.0 26.8 22.1 18.8 19.1 18.7 18.7 33.7 35.3 19.4 36.0 33.6 28.7 14.4 39.9 27.0 28.9 15.1 37.1 27.0 41.1 11.3 18.3 22.5 14.8 22.5 18.7 55.2 21.6 14.9 20.9 36.7 21.1 27.6 31.0 29.7 35.4 21.8 30.8 15.1 18.4 26.0 25.7 24.7 29.1 26.6 23.3 22.0 18.5 36.6 17.7 15.0 17.3 14.9 31.2 42.3 32.0 38.8 50.0 19.6 35.6 39.7 24.4 23.0 26.3 5.0 10.7 7.7 17.8 15.2 21.2 13.1 17.7 18.4 15.2 10.1 17.5 16.9 0.8 23.0 11.4 11.1 16.7 11.0 25.9 32.1 21.7 27.1 22.1 27.6 22.6 28.8 29.2 16.5 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 68.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Enhanced Cytosol 280000 Cytosol "HPA006237: AB_1080502, HPA006428: , HPA071014: " "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavourable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 23.1 16.8 11.5 22.5 11.9 88.9 17.8 21.1 15.7 14.5 14.5 5.2 11.9 11.4 12.7 12.4 16.1 14.1 11.2 15.2 9.6 6.2 13.8 20.4 23.8 26.2 11.6 9.4 22.5 15.8 18.9 22.5 31.0 14.9 12.4 13.8 7.6 16.2 10.7 28.5 23.0 19.7 16.3 16.2 35.6 14.3 20.0 11.0 33.1 14.1 15.4 18.9 18.4 17.9 5.7 6.0 68.5 14.2 3.3 12.1 4.8 9.3 8.8 8.8 7.6 13.9 16.3 15.7 15.2 13.5 13.5 12.1 8.8 9.4 10.0 8.7 13.0 10.2 11.7 13.2 15.8 11.0 7.2 13.7 7.5 6.7 13.5 21.7 33.4 11.8 13.8 15.9 14.2 15.9 44.4 19.4 12.4 10.4 12.9 11.0 12.9 13.0 8.3 9.3 16.1 12.5 10.8 11.1 5.3 17.6 11.2 8.6 14.7 13.0 19.0 10.5 10.5 16.3 9.4 9.2 10.2 11.4 12.0 17.7 11.8 27.2 14.2 13.8 3.4 7.3 3.5 5.7 4.6 3.2 4.9 4.7 5.9 3.5 68.5 3.3 5.8 6.0 12.1 4.8 11.5 11.9 21.1 15.7 9.6 6.2 11.6 9.4 14.9 11.0 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 25.4 21.7 24.4 27.4 24.2 20.4 22.8 32.4 23.1 24.2 24.3 13.5 23.6 20.4 22.6 28.2 27.1 19.4 17.0 23.8 23.8 22.6 28.4 34.0 16.8 20.7 25.8 19.5 27.3 23.6 31.6 41.6 45.9 25.3 26.0 22.3 13.3 20.6 28.8 35.8 16.1 33.2 26.2 28.6 29.1 20.8 20.1 25.3 37.6 28.4 25.6 25.5 30.8 17.1 30.9 23.5 21.2 20.5 19.9 26.2 10.1 21.8 8.7 13.9 12.5 9.9 16.3 13.1 21.3 14.2 14.8 14.1 10.9 14.2 22.3 6.5 20.4 10.0 17.2 15.5 19.4 21.3 18.3 29.7 10.6 12.1 14.7 29.1 16.5 13.9 16.4 19.3 17.8 14.2 24.4 39.4 17.1 10.0 17.9 10.6 14.8 11.3 12.0 34.3 25.5 12.2 15.8 15.1 16.1 13.8 22.1 18.7 15.2 20.0 14.2 17.3 21.6 15.9 21.9 33.7 46.2 23.4 18.1 21.2 17.2 21.2 16.2 20.9 25.4 16.1 19.8 26.4 23.9 22.8 14.9 30.9 26.2 24.8 15.5 19.9 20.5 23.5 24.5 10.1 24.4 24.2 32.4 23.1 23.8 22.6 25.8 19.5 25.3 25.3 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17-like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell line enhanced" "Detected in single" "HEK 293: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " "unprognostic (2.01e-1)" 0.1 0.4 0.1 0.1 0.5 0.0 0.2 0.8 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 1.0 1.1 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17-like family member 22" D6RA61 4 9267619-9269570 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17-like family member 24" Q0WX57 4 9325165-9327116 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17-like family member 25" Q0WX57 4 9329911-9331862 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17-like family member 26" Q0WX57 4 9334658-9336609 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17-like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17-like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17-like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17-like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17-like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18149899-18177397 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA044768 Uncertain Approved Cytosol Cytosol "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 20.4 6.4 4.8 13.0 4.8 6.3 15.4 1.9 5.5 5.3 6.3 5.6 3.2 5.2 6.1 9.5 6.0 6.5 7.1 5.4 4.4 4.6 8.8 20.9 14.0 15.9 4.3 4.8 4.9 4.2 3.8 7.8 7.6 4.7 4.8 3.9 5.7 11.7 2.3 9.7 4.2 15.5 4.5 4.1 10.6 6.4 10.6 4.0 22.4 10.6 2.9 7.7 4.3 6.9 4.1 2.9 6.6 8.8 11.0 11.0 4.8 3.7 3.7 1.1 4.8 4.9 3.6 4.9 1.9 4.5 48.0 52.3 0.6 5.2 0.0 2.9 1.0 1.3 5.6 1.6 1.6 16.4 7.8 7.2 0.5 6.8 0.5 1.7 6.9 1.6 0.6 3.4 0.0 10.6 0.3 0.4 0.4 6.3 8.3 4.2 3.4 2.9 3.3 7.5 0.0 0.9 3.1 4.0 3.2 2.3 3.9 17.8 2.6 1.7 17.4 0.3 0.9 1.1 1.9 0.9 11.2 0.0 4.3 4.3 2.7 2.7 3.2 6.6 7.8 8.8 10.0 4.1 6.7 10.1 1.6 2.7 7.9 8.8 0.5 11.0 6.6 2.9 11.0 4.8 4.8 4.8 1.9 4.0 4.4 4.6 4.3 4.8 4.7 4.0 USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (3.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-3)" "unprognostic (2.69e-1)" "unprognostic (3.65e-2)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "prognostic favourable (7.05e-9)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-3)" "unprognostic (7.54e-2)" 13.9 19.5 10.3 14.6 12.2 16.2 14.9 19.4 37.1 17.0 16.3 12.5 19.6 14.6 18.7 17.9 14.3 17.2 19.9 17.9 10.3 9.4 14.8 16.5 14.7 13.8 11.9 9.5 17.2 15.2 22.4 13.2 17.6 11.4 14.2 10.9 14.9 24.7 26.0 57.3 18.4 16.1 13.9 8.5 17.5 15.1 14.9 11.7 23.0 17.7 15.2 12.6 17.4 14.1 5.1 6.7 12.3 5.7 4.3 8.4 5.3 8.1 11.8 14.1 19.9 17.4 11.9 18.0 9.2 12.3 17.2 13.1 11.8 12.5 17.6 9.4 11.5 10.9 17.8 13.4 7.2 13.8 13.8 17.1 23.6 10.8 18.0 19.4 18.1 16.9 10.4 16.2 11.8 11.3 13.4 13.3 8.6 10.6 18.4 20.1 26.7 17.3 8.9 10.4 20.4 10.6 15.6 7.8 22.2 13.6 17.9 16.0 12.1 25.8 8.9 11.5 14.0 17.0 13.9 33.7 32.6 15.6 14.8 15.4 14.3 12.3 4.9 7.5 7.2 5.3 6.8 4.6 5.8 8.4 6.7 5.1 5.7 6.2 8.8 4.3 5.7 3.0 4.1 5.3 10.3 12.2 19.4 37.1 10.3 9.4 11.9 9.5 11.4 11.7 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381726 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 79.9" "Cell line enriched" "Detected in many" 4 "U-266/70: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favourable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 3.1 4.8 6.9 1.4 12.2 1.5 1.6 12.6 16.1 2.5 5.9 10.0 0.0 7.9 2.6 6.4 5.9 7.0 2.2 26.8 5.7 3.1 29.7 10.6 2.2 0.7 5.7 6.2 2.9 10.1 18.4 7.6 1.3 6.7 2.3 3.9 19.1 3.2 2.4 79.9 4.6 11.7 4.2 3.8 0.8 2.7 36.1 8.8 0.0 2.2 25.2 1.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 3.4 0.3 0.5 1.9 0.1 0.1 0.7 0.4 0.2 0.0 0.3 3.6 0.5 5.9 1.1 0.6 0.6 4.7 1.7 0.1 4.2 0.6 1.7 2.5 7.3 1.6 0.0 1.6 0.6 0.3 0.4 1.2 0.3 8.2 0.5 1.0 2.4 0.0 0.4 0.9 0.7 0.0 1.3 0.8 2.7 0.2 7.2 2.2 2.0 1.6 0.4 5.3 3.6 0.0 0.0 0.9 0.5 0.5 34.4 7.6 0.1 0.0 1.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 0.3 0.3 6.9 12.2 12.6 16.1 5.7 3.1 5.7 6.2 6.7 8.8 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881838 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 30.4;MOLT-4: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favourable (8.01e-4)" "prognostic unfavourable (2.48e-4)" "prognostic favourable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favourable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favourable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 7.8 13.2 10.5 15.2 14.6 24.4 8.5 23.0 19.6 13.2 12.1 12.7 10.2 9.7 13.3 6.2 9.3 11.6 12.5 8.8 10.5 13.7 8.0 7.3 9.1 19.6 9.6 16.1 16.8 12.9 11.5 19.0 8.0 11.9 14.9 6.1 10.8 13.7 17.2 10.2 14.0 11.8 20.0 8.8 14.6 10.2 14.0 8.8 51.5 19.3 4.2 15.3 15.6 10.0 3.8 2.4 4.8 1.7 9.0 10.7 5.4 3.0 2.9 5.2 7.0 6.8 5.8 7.4 4.9 4.1 3.7 2.6 2.4 3.3 4.1 4.2 4.7 7.6 3.1 3.5 1.5 22.2 4.1 7.6 8.0 1.6 4.8 7.1 5.7 5.1 5.1 4.9 3.7 4.0 30.4 5.1 2.2 8.0 27.8 16.9 4.1 7.0 4.7 5.8 7.0 2.9 3.3 1.1 5.8 5.7 7.2 4.6 7.5 10.0 5.9 4.1 1.9 5.5 3.2 5.1 7.4 2.9 8.2 9.4 3.8 1.0 1.7 4.8 8.6 1.4 9.3 3.7 8.8 8.3 2.4 3.8 10.4 8.9 2.8 9.0 1.3 2.1 10.7 5.4 10.5 14.6 23.0 19.6 10.5 13.7 9.6 16.1 11.9 8.8 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favourable (3.35e-5)" 11.8 16.4 22.1 12.8 21.2 15.3 19.1 23.6 24.8 18.1 16.1 25.5 14.0 15.5 19.7 14.6 18.3 33.3 14.1 13.7 20.9 12.1 15.4 10.6 14.0 16.7 26.4 14.1 28.3 19.0 24.4 17.2 15.2 20.5 18.1 13.1 17.1 19.0 25.3 19.4 23.5 15.4 15.1 17.0 18.7 16.0 17.0 22.9 16.0 24.5 9.6 15.6 17.9 19.2 14.1 12.0 18.3 11.1 13.4 17.2 10.7 7.4 12.8 16.9 16.3 13.5 11.3 10.4 5.5 9.0 15.2 11.9 11.8 14.7 9.7 9.5 6.8 12.9 10.9 10.7 8.4 18.5 18.3 11.6 18.5 9.2 9.7 10.3 8.7 9.5 14.4 10.4 15.0 10.7 17.1 13.6 9.6 13.7 18.2 16.2 15.8 16.3 17.3 5.6 16.3 8.9 8.9 15.4 19.8 10.3 10.8 8.3 23.8 16.6 6.2 10.9 9.7 7.6 9.4 27.5 21.3 14.4 10.0 8.9 9.8 13.0 11.1 18.3 14.9 7.1 17.2 12.8 13.8 15.4 12.0 14.1 16.0 14.6 9.6 13.4 7.7 12.0 13.3 10.7 22.1 21.2 23.6 24.8 20.9 12.1 26.4 14.1 20.5 22.9 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999593-21043760 "Enzymes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavourable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favourable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 22.5 33.0 40.7 21.5 49.5 25.9 24.6 66.1 66.4 26.8 23.6 31.9 25.1 18.9 36.7 29.3 21.9 33.9 23.0 44.1 38.7 47.6 27.7 22.9 26.1 25.1 31.0 40.7 45.6 24.5 47.4 32.2 22.4 35.1 27.5 20.5 28.7 20.0 29.5 47.6 22.1 21.1 31.2 24.8 23.7 22.7 20.2 23.7 41.2 32.8 24.8 27.3 25.1 23.2 13.7 12.1 13.4 13.3 8.9 15.5 6.9 21.6 39.4 38.3 32.9 22.4 23.3 18.3 25.0 19.3 22.6 19.2 45.4 9.8 29.8 24.1 38.4 23.4 37.1 29.8 33.8 14.2 25.7 24.7 26.2 22.0 26.5 27.1 21.6 25.6 17.9 25.5 26.9 28.1 28.0 10.8 31.9 22.3 37.9 12.9 19.7 13.0 42.0 60.6 20.3 20.8 31.9 18.5 38.1 32.3 13.4 26.3 22.5 16.1 35.6 23.1 30.7 23.6 33.8 11.7 15.6 99.0 23.5 14.5 35.6 6.8 13.3 12.6 11.0 9.8 11.1 10.9 11.7 10.9 12.1 13.7 15.5 14.6 13.4 8.9 12.2 10.2 7.8 6.9 40.7 49.5 66.1 66.4 38.7 47.6 31.0 40.7 35.1 23.7 USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215113 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA026723: AB_10599851, HPA028428: AB_10600991, HPA067124: " "unprognostic (2.28e-1)" "unprognostic (9.81e-3)" "unprognostic (4.70e-3)" "unprognostic (4.86e-3)" "unprognostic (9.31e-3)" "unprognostic (4.84e-3)" "prognostic unfavourable (1.34e-7)" "unprognostic (2.04e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (8.12e-2)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (4.12e-2)" "unprognostic (1.64e-1)" 12.3 7.6 7.5 12.1 8.8 30.1 10.6 20.1 8.5 7.8 10.2 6.8 10.6 5.0 10.1 7.0 7.7 6.9 7.0 14.7 7.9 6.4 10.4 9.3 7.6 12.7 8.0 5.6 10.9 7.3 15.5 16.9 5.8 6.9 7.6 8.5 5.1 9.7 10.7 46.0 8.9 8.7 7.3 6.2 10.9 7.8 4.9 8.7 16.4 7.4 11.5 12.7 9.7 13.7 6.0 10.5 5.9 2.2 3.8 4.5 1.1 17.8 9.8 12.3 6.7 16.1 14.1 14.2 7.9 10.0 11.4 11.9 14.0 6.3 14.3 8.8 14.6 14.5 16.3 13.3 17.9 15.0 9.9 28.7 21.5 16.3 9.6 19.7 22.3 12.3 11.9 17.3 19.7 10.3 26.4 6.0 15.2 4.2 11.9 10.5 18.1 11.9 12.3 15.7 6.2 19.8 12.1 10.9 7.6 13.5 9.7 11.8 6.7 9.8 13.9 10.4 10.1 12.5 12.6 7.6 5.7 18.8 9.9 16.5 9.3 5.9 2.0 2.5 4.5 1.8 2.8 4.8 3.5 3.5 1.8 6.0 3.2 4.2 2.3 3.8 2.2 10.5 1.9 1.1 7.5 8.8 20.1 8.5 7.9 6.4 8.0 5.6 6.9 8.7 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 14.9 8.5 11.0 14.2 15.5 12.4 28.7 11.3 11.1 17.5 11.8 6.6 17.8 6.5 20.7 14.5 12.6 10.6 10.1 17.8 9.9 5.8 12.9 10.4 22.1 14.8 7.6 7.1 14.5 8.2 8.1 8.4 17.7 7.7 12.9 8.6 7.8 11.4 13.6 56.3 8.3 12.3 19.2 7.3 11.6 9.0 26.1 7.5 16.5 10.5 14.6 9.6 13.8 18.1 3.1 2.8 5.8 2.9 2.3 7.2 1.6 13.0 9.9 9.4 1.4 17.3 25.9 11.0 9.4 9.4 7.0 8.9 8.6 7.5 14.1 13.9 14.8 7.0 7.2 12.4 9.7 14.0 8.2 11.5 10.5 6.6 28.8 15.2 5.3 16.8 15.2 11.3 32.7 24.5 14.8 26.6 12.6 5.4 17.3 2.9 11.5 8.8 13.2 8.7 10.7 19.0 3.5 2.0 5.6 13.4 11.4 8.7 6.1 8.9 23.3 10.9 7.1 11.4 5.2 7.8 4.7 11.2 7.1 6.8 8.0 0.0 2.9 3.6 4.0 2.8 4.4 3.1 3.4 7.2 2.5 2.2 3.2 4.8 5.8 2.3 2.5 2.8 4.4 1.6 11.0 15.5 11.3 11.1 9.9 5.8 7.6 7.1 7.7 7.5 USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133024631-133097109 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 3.8" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (7.92e-4)" "unprognostic (3.59e-2)" "unprognostic (1.99e-2)" "unprognostic (2.08e-1)" 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.1 0.1 3.8 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.0 0.0 0.5 0.4 0.5 0.4 0.1 0.1 0.2 0.2 0.7 0.1 0.2 0.1 0.7 0.1 0.1 0.1 0.7 0.1 0.2 0.3 1.0 0.3 1.0 0.3 0.1 0.1 0.0 1.5 0.6 0.4 0.1 0.1 0.4 0.4 0.2 0.2 0.1 0.7 0.4 0.3 0.4 0.1 0.0 0.9 0.5 0.5 0.2 0.1 0.1 0.2 0.1 0.7 0.3 0.9 0.1 0.3 0.4 0.9 0.3 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27, X-linked" A6NNY8 X 49879948-49882565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA077264: " "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favourable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.8 3.3 1.8 5.9 2.9 0.3 7.7 1.7 7.4 3.9 5.9 4.8 2.2 1.1 12.7 4.1 3.1 4.7 3.8 3.9 2.2 3.5 3.5 6.1 1.9 1.3 3.2 8.8 3.2 4.1 0.8 15.5 2.8 4.1 1.7 4.1 5.2 3.9 7.5 2.6 4.7 3.9 1.3 2.0 1.9 3.8 1.9 2.8 3.2 3.6 2.2 3.7 3.1 1.7 1.0 0.7 0.7 0.3 1.3 0.4 2.1 5.6 6.5 7.5 6.2 5.0 5.4 2.4 4.1 2.8 2.3 10.0 2.5 1.4 2.3 6.4 3.6 9.3 6.2 4.1 2.9 4.3 2.3 1.6 9.2 4.2 0.7 5.1 7.0 4.2 4.0 4.0 3.9 4.6 2.4 4.5 5.3 3.5 2.0 7.0 3.9 3.7 5.6 0.5 4.6 2.1 1.7 4.9 4.8 4.5 5.8 5.2 1.7 2.9 3.3 6.4 5.7 0.9 2.2 0.5 1.0 3.8 2.0 3.6 0.7 0.4 0.1 0.6 0.4 0.8 0.6 0.5 0.3 1.0 1.7 0.8 0.6 0.7 0.3 0.7 0.4 1.3 0.4 USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875570 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.1;skeletal muscle: 50.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA006778: AB_1080520, HPA006779: AB_1080517" "unprognostic (2.54e-1)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.30e-1)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.04e-3)" "unprognostic (1.82e-3)" "unprognostic (3.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.11e-2)" "unprognostic (2.06e-2)" "unprognostic (9.03e-2)" "unprognostic (1.35e-3)" "unprognostic (5.03e-2)" 3.9 3.4 4.8 8.6 5.7 2.4 5.7 26.4 8.6 11.6 5.1 4.9 14.0 4.7 6.0 6.0 5.7 5.0 4.0 40.1 5.0 4.8 5.1 5.6 5.1 7.2 6.8 4.5 7.5 4.1 10.6 9.7 3.9 4.8 8.9 6.0 5.7 5.7 12.2 50.2 3.5 5.1 11.6 6.4 6.9 4.4 5.5 3.8 3.6 5.1 10.1 7.7 7.1 4.6 10.3 4.1 2.1 3.7 17.9 16.2 6.0 10.3 11.6 15.7 20.7 12.8 12.7 11.1 7.6 10.5 10.3 17.7 17.1 14.9 13.7 17.4 10.3 20.3 22.1 14.3 14.4 15.3 10.0 7.3 8.1 9.2 7.9 9.4 7.3 7.6 10.9 11.9 14.2 18.6 12.6 8.9 10.8 5.2 7.1 15.3 18.8 8.4 17.6 21.8 16.6 11.4 10.2 6.9 7.4 18.1 6.2 5.9 15.1 3.3 9.8 11.5 17.2 10.4 7.8 6.1 8.7 11.6 1.1 18.3 7.4 0.1 3.2 2.1 16.2 2.4 8.4 10.3 4.1 11.4 4.1 8.4 2.7 9.4 0.9 17.9 3.7 1.2 5.6 6.0 4.8 5.7 26.4 8.6 5.0 4.8 6.8 4.5 4.8 3.8 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "blood: 4.1;bone marrow: 2.7;pancreas: 2.1;skin 1: 2.3;testis: 8.4" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA076515 Enhanced "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.1 0.2 0.0 0.2 2.7 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.2 2.3 0.1 0.0 0.1 0.1 0.4 8.4 0.4 0.0 0.7 0.1 1.1 1.9 4.1 1.1 1.2 0.8 0.6 0.1 0.7 0.8 0.3 0.0 0.0 3.3 0.0 0.0 0.1 0.1 1.7 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 1.0 3.2 0.8 0.0 0.0 1.1 0.0 1.9 0.9 1.0 1.4 0.0 0.0 0.3 0.9 0.0 0.7 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.0 2.1 2.0 0.7 0.6 0.4 0.2 0.8 1.3 1.5 1.2 0.5 0.0 0.0 1.6 0.5 1.5 0.5 0.8 0.0 3.1 1.1 1.1 0.8 0.7 0.6 0.5 0.7 0.3 0.3 1.1 0.7 0.7 4.1 1.2 0.4 1.9 0.5 0.6 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 33.4" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA053275: , HPA060513: , HPA077975: " "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favourable (1.38e-4)" 16.0 9.0 5.9 20.4 6.5 38.6 21.3 33.4 6.6 12.7 19.1 6.0 16.8 16.2 18.1 13.3 13.6 10.4 14.2 7.6 6.6 4.4 12.9 10.8 17.5 28.2 8.1 3.9 19.5 27.1 7.1 8.2 10.2 7.9 12.4 11.5 8.2 18.5 14.8 12.4 15.9 19.0 16.1 8.0 23.6 14.7 10.3 7.8 22.7 12.5 11.4 22.5 21.3 17.9 11.4 20.6 52.6 28.1 7.2 12.9 13.4 9.2 30.1 15.6 9.7 7.7 12.6 13.7 7.9 9.9 7.7 9.4 11.8 17.3 9.3 12.6 7.8 11.7 14.5 12.3 7.5 15.3 7.8 10.6 10.7 12.7 6.5 6.2 12.8 9.0 16.2 9.3 16.2 16.6 14.0 11.9 4.9 14.3 13.0 10.2 19.7 13.0 19.1 9.4 16.5 9.2 31.6 13.7 10.6 4.9 16.1 9.7 9.7 12.2 15.8 8.9 18.5 5.2 10.5 10.8 19.9 20.8 8.5 17.4 7.3 28.8 28.1 3.5 8.4 22.6 9.3 10.3 11.9 8.6 20.6 11.4 12.9 9.3 52.6 7.2 18.7 4.1 9.1 13.4 5.9 6.5 33.4 6.6 6.6 4.4 8.1 3.9 7.9 7.8 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088026 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favourable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 11.7 18.9 12.7 9.0 17.6 12.2 10.4 11.9 21.0 10.3 13.2 29.2 13.6 14.9 12.4 8.5 9.2 11.1 8.4 9.0 10.3 10.6 12.4 21.7 8.9 10.4 16.6 7.8 17.5 12.4 14.7 13.0 6.7 16.0 9.4 11.3 16.4 10.1 12.4 16.4 13.6 14.1 8.6 14.3 9.8 8.5 21.3 16.3 8.7 11.1 5.3 7.1 10.8 8.1 14.2 12.2 12.7 11.0 18.3 17.4 6.0 4.7 3.6 9.7 8.3 6.8 7.8 5.4 5.3 6.9 6.2 5.5 4.3 3.6 11.9 4.5 5.2 5.3 8.4 5.5 7.1 13.8 10.6 3.8 3.3 6.1 7.3 7.6 4.3 9.4 6.7 5.5 5.4 7.1 5.7 5.8 5.2 5.5 11.9 4.3 3.0 10.2 12.9 6.9 7.2 5.0 5.7 8.8 7.9 7.2 5.4 5.6 13.4 5.9 5.1 5.7 3.1 5.5 3.5 14.6 12.1 17.9 6.1 4.6 6.3 9.5 7.1 12.7 15.4 11.0 17.4 14.2 12.9 14.3 4.6 14.2 13.7 12.6 4.2 18.3 8.8 12.2 11.2 6.0 12.7 17.6 11.9 21.0 10.3 10.6 16.6 7.8 16.0 16.3 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavourable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 6.3 5.3 11.2 4.0 16.6 7.1 8.7 12.7 16.5 10.9 4.9 19.7 2.6 3.7 15.3 7.7 9.3 6.5 4.1 11.0 9.0 6.3 6.2 7.7 7.3 3.6 24.6 8.1 3.7 6.3 20.6 10.4 7.4 17.4 9.6 4.9 2.8 6.0 8.5 10.9 15.9 3.4 14.2 14.8 2.8 3.5 20.7 19.3 1.7 4.2 2.4 4.9 13.4 9.5 0.5 0.8 0.6 1.3 0.1 2.1 0.2 9.4 10.0 2.9 4.0 5.3 4.1 2.7 3.3 3.0 4.3 5.1 6.3 5.8 3.2 3.5 4.1 12.5 7.1 12.9 7.1 2.3 2.9 1.3 5.8 13.2 6.6 3.3 3.6 3.5 11.2 7.9 18.3 7.6 3.8 9.9 5.8 6.5 1.6 2.7 5.7 3.1 7.9 8.1 6.3 6.4 14.2 7.7 5.0 5.1 10.2 2.9 4.1 7.3 4.4 8.7 6.4 4.4 8.9 3.3 5.4 3.4 6.2 4.4 3.4 0.1 0.7 0.6 0.8 0.3 2.1 0.1 0.7 1.5 0.8 0.5 0.8 0.8 0.1 0.1 1.3 0.2 1.3 0.2 11.2 16.6 12.7 16.5 9.0 6.3 24.6 8.1 17.4 19.3 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60179094-60422470 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Cell line enhanced" "Detected in all" "MCF7: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 28.4" "Group enriched" "Detected in many" 10 "dendritic cells: 28.4;granulocytes: 13.5" HPA044365 Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA044365: " "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 9.5 13.9 17.3 10.8 19.5 20.6 10.9 14.6 20.3 8.0 8.5 18.9 7.9 7.2 8.2 5.4 13.1 7.4 9.1 11.1 14.7 12.2 15.5 19.7 12.5 8.6 18.8 14.3 7.4 8.5 17.3 11.4 9.8 19.2 8.7 8.9 11.6 8.2 9.0 23.0 12.2 7.2 9.8 16.5 12.1 8.1 58.4 18.1 7.3 15.6 7.9 8.5 8.8 8.5 1.4 28.4 13.5 2.1 0.6 1.1 0.9 10.9 12.5 6.6 10.6 16.8 15.8 6.3 9.0 13.5 11.7 15.1 6.5 7.1 6.8 7.5 16.5 5.8 11.3 12.4 20.7 5.1 5.0 13.5 9.9 7.1 16.8 10.7 12.4 14.8 9.1 15.8 14.6 12.8 13.7 5.6 14.5 60.4 10.8 7.6 7.8 6.0 5.2 17.6 4.1 12.3 8.0 4.7 7.0 7.4 2.2 11.5 9.2 14.9 10.8 17.9 18.7 11.2 8.3 5.8 11.0 6.3 8.9 8.4 11.6 4.3 2.1 7.2 1.0 1.8 0.7 1.4 0.7 0.8 4.1 1.1 0.5 1.0 13.5 0.6 2.0 28.4 1.1 0.9 17.3 19.5 14.6 20.3 14.7 12.2 18.8 14.3 19.2 18.1 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 30.8 27.1 28.1 18.8 32.1 24.6 28.6 55.3 37.5 21.6 20.4 20.6 18.5 20.2 23.3 23.0 17.8 19.2 21.7 17.0 30.7 30.6 26.0 20.3 21.0 20.7 26.0 25.4 25.3 17.0 28.8 23.4 34.6 38.7 24.6 21.0 21.4 19.5 19.8 16.3 19.4 23.8 19.8 21.4 22.3 19.5 19.9 21.6 27.8 25.1 12.9 20.3 21.0 20.0 15.7 12.2 33.2 18.4 12.3 17.8 10.6 16.3 7.5 25.9 17.9 37.3 32.6 22.3 17.9 17.1 21.9 24.6 9.9 14.1 12.2 17.0 17.4 12.9 18.8 12.3 26.8 11.2 14.7 43.1 18.3 8.6 23.2 14.7 10.9 24.0 9.7 21.1 15.5 19.4 16.8 10.7 16.4 6.3 13.2 14.7 25.0 14.8 12.8 27.3 8.6 20.6 16.8 21.8 16.8 12.5 16.7 25.0 9.3 16.0 16.2 20.2 14.4 20.3 16.9 8.7 11.1 11.9 15.3 17.4 10.2 33.2 15.4 20.0 15.1 15.0 15.3 13.4 14.7 15.2 11.5 15.7 17.8 15.6 20.9 12.3 18.4 12.2 13.2 10.6 28.1 32.1 55.3 37.5 30.7 30.6 26.0 25.4 38.7 21.6 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61470769 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm Nucleoplasm "HPA025815: AB_1858681, HPA070764: " "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 17.2 19.6 31.8 37.2 25.6 24.8 28.3 77.1 35.5 22.5 22.7 14.4 31.1 11.4 22.2 44.5 18.6 17.5 20.0 16.9 30.5 24.0 20.5 21.5 29.7 34.2 22.0 21.2 24.7 17.2 33.5 40.3 13.4 22.0 22.7 21.5 21.2 16.9 45.2 27.0 31.6 21.0 22.7 20.8 24.8 19.3 26.4 25.3 21.7 23.2 13.9 33.5 19.1 16.7 6.0 5.8 3.4 4.6 5.2 7.5 2.3 16.6 11.9 15.5 16.0 29.5 19.8 13.0 10.3 14.5 9.2 8.8 16.7 6.4 39.5 10.9 22.1 9.1 12.2 13.5 17.2 14.1 9.6 23.9 11.6 26.8 24.8 17.7 15.2 21.6 17.5 16.7 25.1 19.3 16.3 12.8 20.4 15.6 11.6 25.8 10.5 9.4 12.5 18.9 10.5 27.1 20.4 12.8 13.7 16.2 12.0 17.7 6.3 12.9 17.2 14.6 19.4 8.6 13.4 14.9 7.3 41.5 13.7 16.5 12.5 3.4 2.0 2.8 7.5 2.2 6.7 5.1 5.1 5.5 1.8 6.0 5.8 7.5 3.4 5.2 4.6 5.8 4.5 2.3 31.8 25.6 77.1 35.5 30.5 24.0 22.0 21.2 22.0 25.3 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78214711 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA055213: , HPA058592: " "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 4.9 17.1 5.1 5.4 9.3 3.8 5.2 10.4 15.0 6.4 5.8 8.0 6.3 5.5 6.8 5.4 5.6 5.4 5.6 8.7 6.1 6.7 5.0 13.8 5.6 4.8 6.7 8.8 6.6 6.4 32.4 12.0 7.1 15.0 5.0 3.4 7.7 4.0 5.6 5.6 3.2 5.3 7.8 4.5 4.6 3.9 5.3 4.0 1.9 7.7 2.9 4.1 5.2 6.6 0.0 0.1 3.4 0.6 0.1 0.3 0.2 2.1 3.3 5.7 6.0 9.8 9.0 3.9 4.9 5.8 5.8 4.1 8.3 4.6 1.7 5.1 9.2 5.7 3.8 7.6 3.4 12.2 2.0 2.8 8.6 4.8 7.6 1.8 8.3 7.6 5.1 12.1 3.5 7.1 3.9 4.2 4.5 1.9 4.6 7.2 1.7 5.3 2.8 5.3 2.1 4.6 3.9 2.8 5.4 3.8 5.0 1.8 4.2 1.5 8.6 10.7 6.1 12.6 2.6 5.7 1.9 2.6 3.2 1.9 6.2 0.0 0.2 3.4 0.1 0.6 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.2 5.1 9.3 10.4 15.0 6.1 6.7 6.7 8.8 15.0 4.0 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nuclear speckles" Nucleoli "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: " "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 26.3 23.4 12.9 21.3 16.0 36.5 28.1 28.3 17.4 17.2 16.4 25.4 19.2 12.3 25.1 22.2 14.6 18.0 21.9 17.4 10.4 11.2 15.9 16.4 20.0 17.2 17.5 16.0 41.3 33.6 19.6 30.0 23.4 14.6 21.0 15.1 20.4 21.8 45.5 19.5 29.3 15.1 25.2 14.5 18.2 17.3 20.8 13.7 12.8 19.3 11.2 22.2 24.6 18.1 6.7 12.4 8.9 5.3 5.6 8.8 2.5 15.7 19.1 5.6 10.4 12.1 13.5 10.8 13.0 13.2 12.5 8.4 18.5 8.0 20.2 6.6 11.5 11.6 13.2 9.6 22.4 4.8 20.0 18.4 27.8 19.2 12.4 20.1 10.1 11.7 16.0 17.8 39.9 10.8 14.6 21.3 10.3 12.1 18.3 20.4 8.7 15.3 14.1 12.3 13.5 7.9 16.6 16.6 10.1 9.3 43.5 23.6 11.2 12.8 9.2 29.5 13.7 17.1 22.9 15.8 6.2 24.8 11.6 15.8 9.2 8.9 3.9 3.1 7.6 5.3 8.8 6.4 7.2 6.4 2.3 6.7 8.0 7.7 5.7 5.6 3.3 12.4 4.8 2.5 12.9 16.0 28.3 17.4 10.4 11.2 17.5 16.0 14.6 13.7 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favourable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 10.4 8.4 9.2 9.7 10.5 19.2 9.0 16.2 10.0 8.3 6.6 10.4 8.0 5.8 9.6 15.8 8.2 7.8 7.0 6.9 7.4 5.5 6.1 7.4 8.1 10.5 8.7 7.8 15.3 6.9 10.7 17.1 8.5 8.7 7.3 7.0 7.4 9.7 9.6 11.1 9.9 7.2 8.1 10.2 7.0 6.6 22.2 10.5 13.4 9.8 5.4 9.4 10.5 9.1 7.4 6.1 7.4 4.8 5.9 9.0 2.5 7.3 5.4 11.4 8.8 3.0 3.7 9.7 5.6 4.1 9.9 11.1 10.2 5.9 6.7 6.2 4.4 7.1 12.5 6.3 10.9 9.2 6.6 18.2 10.9 6.7 3.4 11.8 9.1 2.0 3.8 10.3 7.5 4.2 13.1 13.0 6.2 5.5 15.2 8.1 9.8 4.7 12.3 17.1 6.2 3.4 8.8 12.5 6.8 9.0 4.5 5.7 5.2 8.4 5.3 11.1 9.8 6.2 7.4 8.9 7.8 13.8 6.0 8.8 7.5 6.5 4.2 7.4 7.0 4.8 7.3 5.4 5.8 5.9 4.4 7.4 9.0 5.7 3.5 5.9 4.4 6.1 7.3 2.5 9.2 10.5 16.2 10.0 7.4 5.5 8.7 7.8 8.7 10.5 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Cell line enhanced" "Detected in all" "U-266/84: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA036990: , HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favourable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 7.7 7.8 6.6 6.6 6.5 19.1 8.3 7.4 7.8 7.9 12.1 8.6 8.8 8.8 8.3 7.1 8.6 7.1 7.6 12.5 6.6 5.3 9.3 15.2 12.7 11.1 10.3 5.1 6.3 8.8 10.0 6.2 11.4 5.9 6.6 6.6 7.1 7.2 7.0 45.3 8.9 13.2 6.5 10.8 10.6 7.4 7.5 8.2 22.6 8.6 10.2 8.4 7.8 8.8 6.3 8.1 12.5 5.7 12.3 9.9 5.0 4.7 4.5 4.0 6.8 5.2 5.2 2.9 7.6 7.4 7.0 6.0 12.9 7.0 5.9 5.4 6.4 3.8 9.3 7.5 5.8 14.4 6.0 5.4 5.3 2.7 7.2 10.9 5.4 6.3 6.9 7.2 5.8 7.0 11.7 18.5 4.7 7.5 14.2 2.0 3.6 8.7 9.4 5.9 5.6 4.5 5.5 8.1 7.3 5.9 10.3 6.6 6.3 4.1 8.3 6.5 5.3 5.6 7.9 20.7 35.1 10.7 6.6 8.4 5.4 12.5 5.4 11.7 7.5 5.7 9.6 6.3 6.6 6.5 8.1 5.7 6.7 5.7 5.4 12.3 5.7 3.5 9.9 5.0 6.6 6.5 7.4 7.7 6.6 5.3 10.3 5.1 5.9 8.2 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277831-49340712 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favourable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favourable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 22.1 18.4 21.4 22.4 29.3 41.4 23.1 30.3 32.5 20.7 20.1 26.8 16.9 16.1 23.6 20.9 23.5 19.3 17.5 22.8 22.2 18.0 20.2 18.5 25.7 25.5 20.2 17.5 23.6 17.1 23.6 19.7 22.1 24.3 20.9 21.9 23.6 19.1 21.3 25.7 27.6 19.4 25.9 20.4 30.6 17.7 25.0 19.7 36.8 21.2 14.1 42.4 22.1 22.0 17.0 24.1 59.4 27.3 21.5 18.6 22.2 6.2 7.2 10.1 13.4 18.7 20.1 6.8 17.2 15.3 22.3 20.1 7.7 15.9 12.2 6.8 25.0 8.5 13.4 24.4 20.8 18.8 4.0 27.0 14.4 8.5 27.4 14.2 15.6 20.6 10.7 24.4 20.1 25.7 9.4 19.4 20.6 10.7 16.8 24.2 8.5 12.7 6.9 6.3 10.6 17.5 13.1 8.4 11.2 12.5 8.8 6.3 6.1 22.9 22.8 15.0 8.2 18.7 10.0 15.5 7.5 17.8 13.5 22.6 17.2 18.0 27.3 30.0 16.9 22.1 18.6 17.0 17.6 16.9 24.1 14.1 17.1 15.0 59.4 21.5 24.4 9.6 18.6 22.2 21.4 29.3 30.3 32.5 22.2 18.0 20.2 17.5 24.3 19.7 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved Vesicles Vesicles "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 12.5 20.5 11.0 8.2 17.7 3.5 16.1 8.2 13.5 12.4 12.1 26.1 22.5 11.6 16.2 28.1 13.9 13.4 13.2 10.8 11.3 8.5 16.9 15.7 13.9 7.6 22.1 10.1 19.6 17.2 22.8 24.3 16.3 16.5 16.1 11.2 16.4 13.9 19.7 13.6 21.7 15.2 17.1 20.1 11.4 16.3 23.3 18.9 9.8 21.2 9.4 12.0 18.0 11.8 1.9 5.0 0.4 2.8 1.4 2.2 1.4 9.6 11.3 10.4 7.0 15.3 14.3 9.1 9.6 7.4 8.9 9.7 8.0 11.6 0.2 2.8 15.4 17.3 7.9 17.0 12.8 0.0 5.1 7.7 9.3 13.6 13.3 3.2 5.2 13.6 12.3 13.1 18.5 10.2 12.3 1.9 12.5 7.8 3.4 4.7 4.6 9.2 0.0 21.5 4.5 10.6 15.7 5.7 6.2 7.6 7.9 9.8 9.0 7.2 10.1 12.5 7.8 5.2 11.5 3.5 2.6 0.4 16.1 5.8 10.7 0.0 2.7 0.0 1.3 2.8 0.6 1.3 1.5 1.3 4.0 1.9 1.9 2.2 0.4 1.4 2.3 5.0 2.0 1.4 11.0 17.7 8.2 13.5 11.3 8.5 22.1 10.1 16.5 18.9 USP41 ENSG00000161133 "Ubiquitin specific peptidase 41" Q3LFD5 22 20350578-20390758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell line enhanced" "Detected in some" "NTERA-2: 1.6;RH-30: 4.1;RT4: 1.7;SCLC-21H: 4.9;SK-BR-3: 1.7;U-937: 1.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "unprognostic (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (4.63e-3)" "unprognostic (7.44e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (9.91e-5)" "unprognostic (3.43e-2)" "unprognostic (3.51e-2)" "unprognostic (2.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.63e-1)" 0.7 0.3 0.4 0.0 0.6 1.0 0.6 0.0 1.8 0.3 0.3 1.6 0.2 0.0 0.2 0.2 0.0 0.1 0.4 0.4 0.1 0.9 1.3 0.1 0.2 0.1 0.2 0.0 0.4 0.1 0.4 0.2 0.5 0.0 0.7 0.1 0.3 0.0 0.3 0.3 2.0 0.3 0.4 0.3 0.3 0.1 0.4 1.2 0.3 0.4 0.4 0.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.0 1.6 0.4 0.0 4.1 0.0 0.0 1.7 4.9 0.2 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.8 1.2 1.5 0.3 0.0 0.0 0.3 0.2 0.2 0.4 0.4 0.1 0.5 0.1 0.2 0.0 0.2 0.0 0.4 0.4 1.2 0.4 0.1 USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104884-6161564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064800 Approved Nucleoplasm Nucleoplasm "HPA064800: " "unprognostic (1.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.82e-1)" "unprognostic (6.21e-3)" "unprognostic (2.47e-2)" "unprognostic (3.17e-3)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.66e-1)" 6.7 5.6 5.7 5.7 9.5 19.8 7.2 14.1 10.6 8.5 7.4 10.4 5.5 8.1 14.1 7.0 6.9 8.1 6.5 5.4 5.8 6.0 7.4 7.1 7.3 6.5 6.7 4.9 10.6 11.7 10.5 10.9 8.2 6.2 7.4 6.5 8.9 6.6 6.3 7.4 9.2 9.2 8.7 9.9 7.8 6.7 25.2 8.1 14.3 7.7 6.2 8.3 7.6 6.9 1.9 2.2 3.3 2.4 1.9 4.3 0.8 8.3 6.2 11.3 11.0 6.5 5.0 7.7 4.5 5.8 5.4 5.3 4.4 4.4 9.9 3.0 5.6 7.8 9.4 5.0 5.8 2.4 7.3 4.6 5.3 4.5 5.5 10.6 5.3 5.8 5.9 5.7 7.4 6.5 17.6 6.7 3.5 7.4 6.4 12.0 12.7 4.8 12.2 8.8 6.8 5.0 4.4 8.6 15.3 5.8 12.0 3.6 5.5 5.5 5.5 4.8 17.8 6.0 5.4 6.0 5.0 8.6 4.0 6.5 9.4 2.3 1.1 3.3 2.1 2.4 3.0 1.9 2.6 1.3 1.1 1.1 1.7 4.3 1.4 1.9 1.2 2.2 1.8 0.8 5.7 9.5 14.1 10.6 5.8 6.0 6.7 4.9 6.2 8.1 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729691 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell line enhanced" "Detected in many" "BEWO: 12.3;SK-BR-3: 8.5;T-47d: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762" Uncertain "HPA023389: AB_1858691, HPA027762: AB_10603001" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favourable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.2 0.2 4.2 1.2 3.4 0.9 3.0 0.7 6.0 4.9 10.0 0.6 15.7 6.2 2.9 1.7 6.7 6.3 5.1 0.2 4.1 3.8 3.7 8.7 3.4 0.2 1.7 3.1 1.0 7.7 1.7 3.7 61.6 0.7 10.8 5.0 0.3 11.3 12.4 0.2 2.4 12.5 0.3 1.0 0.2 2.6 2.9 0.2 0.4 1.7 4.2 2.7 1.3 2.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 5.6 1.4 0.0 0.6 0.0 0.0 12.3 0.1 0.2 0.6 1.7 2.8 4.6 0.0 1.9 0.2 6.9 0.6 5.4 0.6 3.6 1.9 0.3 2.9 1.0 0.1 0.5 0.0 0.0 7.1 0.3 3.0 0.0 0.0 0.0 0.0 2.6 0.9 4.6 0.7 0.3 3.7 0.0 0.8 4.3 3.1 0.7 0.0 2.4 8.5 1.0 10.2 1.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 4.2 3.4 0.7 6.0 4.1 3.8 1.7 3.1 0.7 0.2 USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551490 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.8" "Cell line enriched" "Detected in some" 5 "NTERA-2: 54.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in many" 5 "cerebellum: 10.9" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.6" "Group enriched" "Detected in many" 39 "B-cells: 5.6;T-cells: 8.6" "Low region specificity" "Detected in all" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center, Microtubules" "HPA026543: AB_1858692" "unprognostic (2.12e-2)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (1.83e-4)" "unprognostic (7.18e-4)" "unprognostic (5.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.97e-2)" "unprognostic (8.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.41e-2)" "unprognostic (7.07e-2)" 1.3 1.0 0.7 1.2 1.3 0.5 1.4 10.9 2.1 1.7 1.7 1.7 1.4 0.5 3.0 1.0 0.9 1.6 1.1 1.0 0.7 0.6 1.9 0.2 4.7 1.9 1.3 1.2 1.6 3.6 4.8 4.0 0.3 1.8 1.7 0.6 2.3 1.8 2.6 0.4 0.6 1.3 1.2 0.6 1.9 1.0 26.8 1.2 0.8 1.7 0.0 1.6 1.1 2.3 5.6 0.1 0.1 0.0 0.1 8.6 1.3 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.4 1.3 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 2.2 10.1 0.0 0.0 2.4 4.1 0.2 0.0 0.0 0.3 0.0 0.2 1.6 0.0 0.0 0.0 5.2 0.0 54.8 0.0 0.0 0.0 0.0 0.9 0.3 3.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 3.4 5.6 2.3 2.0 0.0 4.4 8.6 5.5 0.1 0.1 0.0 0.1 0.3 1.3 0.7 1.3 10.9 2.1 0.7 0.6 1.3 1.2 1.8 1.2 USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432379-99521728 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" 9.8 9.1 8.5 10.2 12.2 7.2 9.0 28.4 11.6 9.0 9.7 8.6 8.9 13.7 15.7 9.6 10.0 8.1 11.9 11.5 7.7 8.5 12.2 9.0 7.1 12.7 9.8 8.0 10.7 9.6 10.2 21.7 9.6 15.0 9.9 13.1 7.9 9.8 8.4 14.6 11.8 12.4 10.8 10.6 9.9 8.9 5.7 9.4 7.1 10.7 10.4 9.5 8.8 15.0 8.6 5.1 3.7 2.5 2.6 6.2 1.4 4.1 3.0 5.9 8.3 10.9 10.4 6.2 7.2 8.1 7.6 10.8 6.1 4.6 11.1 5.4 7.3 5.6 9.0 7.2 10.5 8.7 8.6 10.8 5.9 4.8 8.4 10.0 6.2 11.1 5.7 6.8 11.6 11.2 26.0 11.0 7.1 3.9 3.2 9.5 9.5 6.4 4.7 4.4 6.2 10.5 4.9 8.3 6.8 5.1 6.8 5.3 3.6 4.9 11.2 4.2 5.3 6.1 11.0 4.7 4.3 20.3 7.2 9.5 7.4 3.7 2.0 0.6 4.9 1.3 6.2 7.4 4.2 5.6 3.5 8.6 3.0 2.9 0.5 2.6 2.5 5.1 3.5 1.4 8.5 12.2 28.4 11.6 7.7 8.5 9.8 8.0 15.0 9.4 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590972-52659335 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved Nucleoli Nucleoli "CAB076369: , CAB076370: , HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.7 9.5 26.0 3.5 20.9 2.8 7.0 23.7 29.4 8.9 4.2 12.8 5.2 4.8 7.2 6.2 12.4 7.8 5.8 28.9 21.9 19.0 10.8 3.1 4.4 3.7 19.1 13.9 12.3 5.6 12.2 5.3 10.6 12.7 7.7 4.6 5.3 8.0 7.8 13.7 8.0 4.5 5.5 18.9 3.5 6.3 12.2 15.0 1.0 10.0 4.3 5.8 7.3 5.7 1.4 4.4 2.0 1.4 1.2 3.9 1.0 5.3 3.8 12.3 9.1 13.5 16.9 13.6 8.8 7.1 6.5 5.5 7.6 4.2 3.5 10.4 8.7 3.1 21.4 10.2 12.0 3.1 7.5 5.5 3.6 8.5 13.5 7.3 6.5 14.4 9.6 6.7 6.3 9.6 5.4 5.0 13.8 4.9 3.1 3.8 9.1 4.6 7.9 9.0 0.7 14.0 9.9 7.4 8.9 4.3 14.7 8.5 5.4 5.5 8.9 6.4 14.0 7.5 13.2 5.2 2.4 2.8 9.9 4.4 7.9 2.0 1.4 0.3 2.3 1.2 1.7 1.4 3.9 2.0 2.8 1.2 0.9 0.8 0.3 1.2 0.9 4.4 1.2 1.0 26.0 20.9 23.7 24.3 21.9 19.0 19.1 13.9 12.7 15.0 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11959323 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 16.6 17.0 17.9 18.5 20.9 20.3 16.9 25.7 19.0 16.4 18.1 16.2 21.3 11.6 18.0 15.0 18.7 13.7 13.5 25.5 18.1 13.4 14.6 25.1 16.6 13.4 21.9 12.9 16.9 19.6 38.8 31.8 23.7 19.3 18.0 14.2 10.2 15.1 19.2 58.1 18.4 15.1 21.3 19.5 13.3 18.1 16.8 23.9 27.9 16.8 12.4 15.2 21.3 19.4 9.7 10.1 14.0 13.2 22.8 19.3 9.7 21.0 12.8 23.1 10.9 16.7 18.4 10.6 24.2 18.3 16.0 18.1 12.6 18.8 23.8 11.5 22.5 14.4 17.8 12.1 24.7 23.2 15.0 14.3 23.8 8.9 14.8 18.5 20.1 17.1 16.7 10.5 23.3 17.8 28.5 20.6 19.5 8.3 16.7 8.2 6.2 10.4 17.2 24.3 7.4 17.2 24.4 8.0 16.4 21.6 15.1 13.4 12.1 13.6 19.6 22.7 13.8 19.3 14.7 6.5 14.9 22.6 15.6 11.4 16.2 13.3 7.7 14.0 15.2 9.5 19.3 9.7 13.8 14.7 10.1 8.6 17.9 15.3 3.6 22.8 13.2 6.1 9.9 9.7 17.9 20.9 25.7 19.0 18.1 13.4 21.9 12.9 19.3 23.9 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavourable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 20.1 38.8 18.6 28.9 30.9 30.9 22.1 48.2 27.5 19.9 18.4 25.6 15.4 17.6 21.3 17.6 19.0 17.4 20.5 17.8 16.9 15.8 15.5 18.3 18.3 26.2 26.6 22.5 27.0 19.8 24.6 35.4 23.1 26.8 21.6 22.0 22.1 24.5 16.3 17.0 23.9 22.2 22.2 19.7 29.1 26.2 15.8 23.6 25.8 23.9 14.0 29.0 19.8 21.0 13.7 10.5 33.7 9.6 5.6 11.2 5.6 14.6 7.0 16.5 11.9 14.3 17.7 16.3 18.5 12.6 12.4 16.5 6.4 15.0 16.5 12.5 16.7 13.6 20.3 14.9 18.9 16.0 13.9 35.3 26.1 11.6 12.8 17.7 18.9 14.3 12.9 12.6 14.1 36.6 27.7 46.8 15.2 7.3 14.6 23.0 10.4 12.6 20.6 16.6 19.3 14.3 12.4 20.1 12.5 17.4 16.0 41.8 8.2 21.4 25.9 13.4 11.1 16.4 10.7 37.5 26.6 16.4 12.9 22.0 19.7 33.7 9.6 16.7 6.4 4.6 7.6 13.7 9.5 9.5 10.5 12.8 11.2 7.0 8.9 5.6 5.0 7.7 10.1 5.6 18.6 30.9 48.2 27.5 16.9 15.8 26.6 22.5 26.8 23.6 USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 23.4;U-698: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain "HPA030254: AB_10600198, HPA030255: AB_10601218" "unprognostic (1.71e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "unprognostic (2.57e-4)" "unprognostic (4.46e-2)" "unprognostic (2.84e-4)" "unprognostic (7.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.19e-2)" "unprognostic (3.22e-1)" "unprognostic (5.59e-3)" "unprognostic (8.28e-2)" "unprognostic (1.26e-5)" "unprognostic (5.39e-2)" "unprognostic (4.58e-2)" "unprognostic (4.37e-3)" "unprognostic (3.24e-3)" 2.4 2.4 7.6 3.5 6.0 7.3 2.7 12.7 9.3 2.3 1.9 2.0 4.3 2.2 4.0 2.3 1.8 2.2 2.1 3.5 7.6 4.2 1.6 1.7 2.4 3.7 3.0 5.8 4.0 3.2 2.6 4.8 1.8 4.2 2.4 2.1 3.7 2.7 2.4 3.8 4.1 2.2 3.2 3.2 3.5 2.2 7.4 3.2 7.3 7.7 0.6 3.4 2.8 2.0 1.2 0.7 8.5 1.8 0.8 0.9 0.4 3.0 0.9 12.3 6.0 1.5 1.6 5.1 1.1 1.1 1.8 2.2 3.9 0.7 12.4 1.3 1.5 1.3 7.6 1.1 2.7 3.0 5.6 4.4 4.6 1.3 1.0 3.4 2.7 1.6 0.9 2.6 1.7 1.1 9.2 3.4 1.4 1.7 13.1 5.2 3.4 1.1 23.4 6.0 2.7 0.7 2.1 8.3 3.4 1.6 0.6 0.6 1.8 3.1 3.1 4.3 4.2 1.4 1.5 6.4 5.6 33.3 0.5 3.5 0.8 8.5 1.3 1.4 0.8 1.5 0.4 1.2 0.4 0.8 0.5 0.9 0.9 0.7 2.4 0.8 1.8 0.7 0.4 0.4 7.6 6.0 12.7 9.3 7.6 4.2 3.0 5.8 4.2 3.2 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852128-6866632 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol 820000 "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 18.6 28.7 23.1 17.8 32.6 13.6 12.9 24.6 50.9 15.9 21.5 26.8 13.8 17.6 22.3 12.8 27.7 19.1 14.7 22.4 23.9 28.6 14.9 24.8 14.4 18.6 23.6 33.2 14.4 13.2 29.7 19.6 21.7 36.8 19.5 16.1 11.6 14.1 22.7 41.2 33.5 18.1 25.3 23.6 14.1 15.9 30.9 18.7 22.8 19.2 20.4 19.9 21.3 16.0 10.8 18.6 5.3 16.6 10.8 17.1 16.6 25.3 39.7 26.7 30.2 18.2 16.8 34.1 27.6 21.2 33.0 24.1 37.5 25.2 30.7 14.5 28.6 22.4 29.3 27.4 21.2 57.5 24.8 28.1 31.9 20.3 14.2 25.4 29.6 16.9 15.9 28.5 19.8 28.2 24.1 12.3 27.2 27.8 38.1 12.6 52.0 16.8 30.0 34.8 21.2 18.8 24.7 14.7 29.7 18.8 28.7 12.0 11.5 20.8 27.3 28.0 33.9 21.3 34.3 14.9 34.2 46.7 31.2 16.2 27.2 2.3 12.3 5.3 17.1 16.6 16.1 10.8 15.2 14.4 18.6 10.0 14.6 14.8 0.9 10.8 14.7 13.6 12.9 16.6 23.1 32.6 24.6 50.9 23.9 28.6 23.6 33.2 36.8 18.7 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 34.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 2.4;naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favourable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favourable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 0.6 2.7 2.0 0.3 2.9 0.1 0.9 2.3 1.8 1.4 0.6 0.0 1.8 34.1 0.2 3.4 0.3 1.0 1.8 3.7 2.2 0.5 0.7 0.4 1.6 4.1 0.8 3.6 1.8 1.3 1.3 0.3 0.3 1.5 0.0 0.5 0.5 1.1 1.4 0.9 0.3 1.3 3.2 0.5 0.7 0.5 0.9 0.0 2.4 0.0 0.6 2.4 0.1 0.0 0.9 5.7 1.7 2.9 1.5 0.0 0.9 0.5 1.1 1.3 1.8 0.8 0.0 6.9 1.2 0.3 1.5 0.6 1.8 1.8 0.1 1.5 0.3 0.0 1.2 3.5 0.3 5.9 0.1 0.6 0.0 0.4 4.4 4.4 0.9 3.8 3.4 1.8 7.2 0.3 4.9 1.1 2.2 1.4 0.2 0.0 1.1 1.6 0.2 5.4 1.4 1.8 0.3 2.3 3.1 0.6 0.2 7.0 2.7 1.4 1.5 2.0 1.5 0.0 0.0 2.4 0.3 0.0 0.0 0.6 0.6 0.0 0.0 0.9 2.4 0.2 0.0 0.6 0.0 0.0 0.0 0.1 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116438-5175034 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 18.2;testis: 29.0" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046969 Uncertain Vesicles Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.3 0.3 0.3 0.3 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.3 1.2 0.0 0.6 0.6 0.3 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.3 2.6 0.3 0.0 0.4 0.4 0.3 0.4 0.1 0.3 0.3 0.3 18.2 0.6 0.7 0.9 0.3 0.3 0.0 29.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.9 1.2 1.9 1.0 0.2 0.4 0.1 2.2 1.0 2.2 1.7 0.4 0.2 2.3 1.9 0.1 0.6 0.4 0.8 1.1 2.2 1.7 1.3 1.0 0.7 0.8 0.5 1.6 1.3 1.7 1.3 0.9 1.2 0.5 2.9 1.1 0.5 0.1 0.2 0.3 0.5 0.3 0.5 2.5 1.9 0.7 1.6 0.1 1.4 2.0 0.2 0.5 0.7 0.9 2.2 1.0 0.1 3.3 2.2 2.2 1.2 1.0 3.3 2.1 1.4 2.0 1.7 1.5 0.0 0.1 2.7 0.1 0.4 0.9 0.4 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 0.4 1.9 0.2 1.0 1.2 0.1 0.1 0.3 0.6 0.5 0.3 0.3 0.1 0.3 0.3 0.3 0.3 USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892094-8964514 "Enzymes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641" Approved "CAB008108: AB_2233500, HPA015641: AB_1858700" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.94e-2)" "unprognostic (9.64e-2)" "unprognostic (8.09e-2)" "unprognostic (4.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.81e-1)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (9.93e-2)" "prognostic favourable (8.56e-5)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (7.31e-2)" "unprognostic (2.69e-1)" 17.8 16.8 23.9 25.8 22.9 37.6 21.3 28.7 24.5 21.2 26.3 16.2 18.4 17.7 23.5 16.4 24.4 20.3 18.7 23.7 22.8 20.8 16.5 21.3 21.0 30.5 19.6 22.6 22.5 24.0 44.4 19.7 19.3 16.2 18.5 27.4 16.0 18.4 20.3 42.2 25.2 21.5 22.7 15.3 22.9 22.6 43.3 16.5 68.8 19.5 22.3 35.1 23.9 31.7 7.5 9.8 5.5 7.8 3.9 8.7 1.8 12.7 23.7 21.0 15.7 11.9 15.3 14.5 17.6 15.1 16.5 14.0 21.2 15.6 30.7 11.2 20.3 15.9 32.1 21.0 27.6 20.1 12.8 25.5 16.0 43.8 17.3 28.0 16.5 13.2 13.3 17.9 21.2 23.3 24.6 34.1 16.7 24.3 41.1 5.4 14.7 13.8 36.6 23.6 28.0 11.5 25.0 19.8 12.2 19.7 18.5 9.7 18.5 12.6 19.9 17.8 18.2 27.3 13.1 16.5 40.4 47.0 16.6 16.4 14.3 5.5 3.3 3.8 7.1 3.2 8.7 5.9 6.6 8.2 3.3 7.5 8.0 6.8 5.2 3.9 7.8 9.8 7.0 1.8 23.9 22.9 28.7 24.5 22.8 20.8 19.6 22.6 16.2 16.5 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514419 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA050215: " "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favourable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 19.4 21.9 21.0 20.6 20.6 21.6 18.1 27.3 21.6 21.4 23.9 13.8 19.5 20.2 22.1 17.4 22.3 17.4 15.5 17.4 19.7 18.2 28.2 26.4 17.0 25.4 21.8 15.2 21.9 16.7 42.6 43.2 29.1 29.7 16.7 18.9 10.7 19.9 17.9 24.3 17.8 32.1 19.2 29.3 30.3 17.7 27.5 26.1 28.9 24.1 12.7 20.9 22.3 18.4 16.7 10.6 38.1 15.1 9.5 11.9 6.9 11.0 15.9 8.9 15.7 16.3 18.3 12.4 15.9 18.9 15.5 18.4 10.6 7.3 11.7 12.3 18.2 21.5 12.2 11.9 18.4 10.2 8.1 21.6 14.8 10.9 16.8 14.4 14.6 14.2 14.3 13.7 23.3 15.0 12.3 14.2 14.5 22.7 9.2 5.7 10.2 7.3 8.4 16.6 17.5 14.7 26.1 11.4 10.4 16.8 25.1 20.8 13.7 17.7 17.0 16.1 9.1 49.6 21.0 11.1 23.1 12.9 12.9 29.2 15.5 38.1 13.3 22.4 11.1 12.4 10.7 16.5 11.4 11.1 10.6 16.7 11.9 10.7 22.7 9.5 15.1 9.9 8.5 6.9 21.0 20.6 27.3 21.6 19.7 18.2 21.8 15.2 29.7 26.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9, X-linked" Q93008 X 41085635-41236579 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 18.0 21.8 17.7 14.0 15.9 15.5 16.8 16.6 16.7 18.4 20.6 11.4 25.4 13.2 19.6 19.0 17.3 17.0 17.1 20.9 14.2 14.2 18.5 34.2 16.7 23.1 15.2 15.4 15.7 16.5 45.8 17.0 41.1 12.9 13.4 14.4 13.9 14.2 25.2 42.8 14.8 22.0 17.3 14.0 16.7 16.9 16.9 14.0 21.1 20.3 17.6 16.5 20.3 19.9 6.4 5.5 13.0 5.0 4.9 7.8 3.1 19.0 22.6 20.1 20.5 16.9 17.7 4.6 11.0 14.8 12.5 14.6 10.4 8.9 12.8 6.2 25.0 12.9 34.5 20.0 21.1 16.1 24.8 14.9 21.9 9.3 14.3 12.9 10.9 15.3 9.0 30.0 28.5 19.3 18.0 10.5 19.3 14.0 9.2 5.1 21.2 12.5 10.1 27.5 8.3 11.9 15.8 11.4 10.7 46.2 12.8 12.6 12.4 7.2 20.6 19.2 14.8 18.1 11.8 9.6 11.2 16.4 13.7 5.8 9.5 3.3 4.7 6.0 5.6 4.2 7.8 6.4 6.6 6.2 5.5 4.7 6.7 6.0 13.0 4.9 5.0 4.2 5.6 3.1 17.7 15.9 16.6 16.7 14.2 14.2 15.2 15.4 12.9 14.0 USP9Y DFFRY ENSG00000114374 "Ubiquitin specific peptidase 9, Y-linked" O00507 Y 12701231-12860839 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 16.0;RT4: 8.6" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 2.0;T-cells: 2.7" "Not detected" "Not detected" HPA057687 Uncertain Vesicles Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 1.2 2.2 1.4 0.9 3.1 1.7 1.1 9.6 4.0 0.0 1.6 1.4 0.0 8.6 4.4 0.0 3.8 2.4 1.8 3.4 2.9 2.2 2.2 1.4 2.1 0.0 2.7 0.0 4.8 1.7 9.3 4.8 2.3 7.6 2.8 2.0 1.8 0.0 1.5 2.2 1.5 2.9 2.8 4.5 3.2 0.0 2.4 2.0 0.1 0.2 0.5 2.7 0.2 0.0 2.2 0.0 0.0 0.0 0.0 2.4 7.1 7.1 3.6 3.9 0.0 0.0 4.0 0.0 5.9 0.0 0.0 0.0 3.2 2.2 0.0 2.5 0.0 7.0 4.0 0.0 0.0 5.9 5.2 0.0 0.0 0.0 0.0 0.0 6.4 0.0 4.0 0.0 1.5 0.0 0.0 2.0 0.8 16.0 8.6 2.8 0.0 0.0 0.0 2.1 0.0 0.0 5.5 4.4 0.0 0.0 3.2 0.0 3.7 7.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.2 2.7 1.2 2.2 1.5 0.3 2.4 2.2 1.3 0.1 0.5 0.0 2.0 1.6 0.2 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.3" "Cell line enhanced" "Detected in all" "ASC diff: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 21.3 23.0 9.3 11.5 11.0 12.9 28.1 9.4 14.5 24.3 19.3 17.1 16.5 12.6 24.0 27.4 18.5 17.8 22.6 20.1 9.8 10.2 29.9 173.3 16.4 17.5 13.7 9.1 25.5 55.5 14.0 25.0 22.5 13.3 22.3 12.6 20.8 34.8 21.4 11.4 15.9 26.8 27.7 12.5 15.4 17.5 18.2 10.6 15.8 25.6 13.8 14.6 28.4 18.7 32.3 49.9 59.6 40.6 24.7 43.7 33.6 10.4 26.9 8.9 25.3 98.2 58.5 9.9 38.9 33.8 19.1 32.6 11.2 12.1 8.2 21.0 48.6 9.7 12.2 15.2 21.8 11.6 29.7 7.5 37.3 53.6 15.5 14.5 11.3 33.8 8.2 26.4 22.7 20.7 9.8 19.6 37.4 37.9 10.6 29.8 16.0 25.9 19.3 23.5 40.9 18.9 9.2 18.1 21.9 17.0 12.4 18.8 20.4 17.7 18.0 25.7 9.2 23.6 14.6 11.9 11.0 7.2 66.9 25.1 13.2 21.5 40.6 59.6 40.3 28.1 39.7 29.9 40.5 40.7 39.6 32.3 36.4 35.4 34.2 24.7 28.3 49.9 43.7 33.6 9.3 11.0 9.4 14.5 9.8 10.2 13.7 9.1 13.3 10.6 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132734765 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "blood: 39.5;bone marrow: 29.8;liver: 29.4" "Cell line enhanced" "Detected in some" "Daudi: 2.5;EFO-21: 3.7;hTCEpi: 2.3" "Cancer enhanced" "Detected in some" "liver cancer: 3.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "neutrophil: 39.5" "Lineage enriched" "Detected in single" 40 "granulocytes: 39.5" "Secreted to blood" 150000000 "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.1 0.1 0.4 3.3 0.4 29.8 0.2 0.2 0.6 2.4 1.2 0.2 0.2 0.0 0.2 0.8 0.9 2.4 1.3 1.0 0.4 0.0 0.3 29.4 6.1 1.2 0.4 0.2 1.2 0.2 0.0 0.2 5.8 0.3 0.5 0.0 0.4 1.1 0.2 0.2 0.1 0.2 0.2 0.2 7.6 0.4 0.3 0.2 0.2 0.3 2.4 0.7 0.6 0.3 0.0 0.0 39.5 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 2.5 3.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 6.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.6 0.4 0.0 0.4 0.2 0.3 0.2 VRK1 ENSG00000100749 "Vaccinia related kinase 1" Q99986 14 96797304-96931722 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavourable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 6.0 4.4 7.1 9.8 17.1 39.0 8.7 8.6 10.2 6.1 7.8 4.4 4.1 5.2 5.9 5.7 9.4 6.9 3.3 6.0 7.4 6.5 6.2 4.3 4.5 18.3 6.9 6.1 5.9 3.7 3.8 5.1 7.1 6.7 5.3 9.1 4.1 4.8 4.1 4.3 6.4 6.9 5.4 6.1 15.7 6.7 33.3 6.9 33.0 4.9 6.1 18.4 5.9 5.7 20.8 13.5 20.1 9.5 28.5 22.3 12.5 15.7 9.1 22.5 10.0 2.7 5.0 14.0 11.9 9.3 19.1 19.0 10.8 15.6 40.1 8.1 7.0 17.5 21.0 15.5 26.3 22.8 11.3 25.0 6.0 11.1 2.9 48.0 15.7 2.7 2.8 14.4 10.6 13.2 21.2 25.4 16.4 18.0 38.1 20.7 14.4 17.3 35.7 39.4 13.6 8.7 16.2 15.9 9.0 10.5 10.8 8.0 12.3 19.0 7.1 8.7 7.8 15.0 11.9 13.3 15.7 38.8 13.6 21.0 10.3 20.1 7.6 14.5 15.1 9.3 18.4 20.3 17.6 18.5 9.9 20.8 19.1 19.3 4.5 28.5 9.5 13.5 22.3 12.5 7.1 17.1 8.6 10.2 7.4 6.5 6.9 6.1 6.7 6.9 VRK2 ENSG00000028116 "Vaccinia related kinase 2" Q86Y07 2 57907651-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: " "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavourable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 18.7 17.7 10.9 21.9 28.3 14.9 16.1 2.4 15.1 15.6 13.5 27.3 16.3 9.9 18.4 16.7 26.8 13.2 10.9 21.6 14.4 8.9 12.4 15.2 15.6 19.5 29.2 13.5 14.2 20.0 16.1 18.7 16.1 18.7 15.7 15.6 9.3 20.5 17.6 21.5 12.8 12.9 20.1 19.0 20.1 13.5 12.5 31.2 13.6 17.4 16.7 23.0 18.1 19.4 19.7 17.0 21.6 21.3 11.3 12.2 9.2 14.1 9.5 1.1 6.3 7.1 13.1 19.6 13.1 13.2 9.1 9.3 19.3 15.1 17.3 17.3 11.5 10.8 13.7 14.3 13.7 31.1 9.2 19.5 7.6 13.8 11.3 16.5 11.6 7.2 17.1 14.6 21.0 26.1 19.1 11.1 15.1 8.1 0.1 12.7 12.0 4.8 18.9 4.8 11.8 15.1 11.7 3.8 0.1 20.8 12.4 10.5 8.7 10.2 14.5 0.2 30.2 8.1 0.2 16.4 12.9 9.3 7.3 20.5 15.0 13.7 16.8 21.6 10.1 21.3 12.2 19.7 9.8 11.8 16.6 19.0 7.4 9.5 6.0 11.3 20.6 17.0 11.5 9.2 10.9 28.3 2.4 15.1 14.4 8.9 29.2 13.5 18.7 31.2 VRK3 ENSG00000105053 "Vaccinia related kinase 3" Q8IV63 19 49976467-50025946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 77.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA056489: " "unprognostic (2.09e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.22e-3)" "unprognostic (9.78e-2)" "unprognostic (3.47e-1)" "unprognostic (8.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "prognostic favourable (1.83e-4)" "unprognostic (9.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "prognostic favourable (5.66e-4)" 9.7 11.9 9.2 9.4 12.7 10.7 8.3 12.0 14.1 8.9 13.4 11.9 9.3 13.4 15.7 10.8 8.4 18.0 12.2 7.4 9.3 11.1 16.7 16.2 8.5 13.4 10.4 9.9 11.2 11.5 7.1 11.8 10.7 9.8 9.4 11.7 14.2 14.3 8.5 11.8 7.7 17.3 7.5 11.0 12.8 10.9 77.2 9.1 24.7 14.1 6.0 12.9 9.9 8.0 24.5 19.7 47.3 20.9 33.5 30.1 18.1 16.3 16.9 12.4 13.4 16.5 15.3 12.9 11.8 14.1 17.5 19.3 9.0 18.3 19.7 8.4 11.4 12.2 11.5 10.0 14.2 17.2 23.7 15.3 10.2 15.6 12.4 19.1 27.0 13.7 15.1 10.1 10.7 14.4 18.6 29.4 12.6 6.9 25.8 12.9 6.7 14.6 20.8 13.1 25.1 15.0 17.3 14.0 6.8 11.5 14.2 12.8 13.1 20.4 10.9 18.0 10.5 7.2 9.1 19.1 24.3 10.3 14.4 11.8 12.3 37.0 17.8 32.4 23.8 18.8 19.1 24.5 21.7 22.7 19.7 21.9 22.1 20.4 47.3 33.5 20.9 18.8 30.1 18.1 9.2 12.7 12.0 14.1 9.3 11.1 10.4 9.9 9.8 9.1 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573681-9593457 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004619, HPA068845" Approved Approved Nucleoli Nucleoli "CAB004619: AB_628447, HPA068845: " "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavourable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 6.9 3.5 2.0 26.1 2.1 6.6 27.4 5.3 1.6 12.8 18.0 2.5 15.4 3.7 21.9 14.3 22.1 12.4 20.2 23.0 2.0 2.2 6.8 19.3 10.2 10.9 1.8 1.2 11.1 4.4 4.9 6.1 42.7 4.7 17.0 4.7 5.9 12.8 17.8 12.0 33.3 10.4 22.9 2.4 8.0 12.5 28.3 2.0 35.9 12.0 26.8 26.4 19.8 14.7 8.5 0.1 6.4 0.0 2.1 7.8 0.6 14.2 5.5 21.2 11.7 18.6 9.3 42.0 17.6 13.6 9.9 9.8 10.1 17.5 33.4 6.6 7.7 17.3 14.5 6.8 12.7 11.9 11.9 13.1 8.9 6.7 2.0 19.8 13.1 3.1 7.4 4.6 16.4 6.1 21.3 23.3 17.2 3.4 20.2 10.7 31.9 6.3 19.5 16.6 7.2 7.8 30.1 7.9 10.5 11.9 14.1 8.6 8.9 9.5 7.0 17.8 12.5 7.2 14.1 5.5 16.3 44.2 7.6 10.9 12.5 0.0 0.0 6.4 2.0 0.0 0.2 8.5 2.0 3.3 0.1 3.6 0.1 1.6 0.1 2.1 0.0 0.1 7.8 0.6 2.0 2.1 5.3 1.6 2.0 2.2 1.8 1.2 4.7 2.0 WEE2 FLJ16107 ENSG00000214102 "WEE1 homolog 2" P0C1S8 7 141708353-141731271 "Enzymes, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027418, HPA054280" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" 0.6 0.1 0.5 0.3 1.0 0.0 0.4 0.8 0.6 0.6 0.1 0.0 0.7 0.0 1.3 0.7 1.6 1.3 0.5 0.6 1.3 0.1 0.3 1.6 0.6 1.2 1.1 0.0 1.0 0.0 0.3 0.0 0.9 0.0 0.7 2.8 0.4 0.0 0.8 0.4 0.8 1.3 2.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.3 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.5 1.6 1.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.2 0.1 1.7 1.1 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.0 0.5 0.0 0.0 0.2 0.0 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752593-911452 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol Cytosol "HPA046541: , HPA059157: " "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 30.0 12.4 49.3 19.1 47.5 28.9 45.4 22.5 36.7 21.2 12.6 42.6 10.6 8.5 15.9 19.4 45.5 16.9 16.5 38.5 53.7 36.4 45.6 18.0 33.0 34.3 62.3 27.1 18.5 11.3 29.1 12.7 20.3 41.4 17.1 14.3 12.0 15.4 20.3 43.4 31.3 10.3 22.3 82.8 16.9 15.7 23.8 38.8 23.9 16.7 17.4 24.5 18.9 26.5 3.7 2.6 10.9 7.1 2.1 5.2 1.9 14.2 27.0 35.7 3.3 25.8 24.8 13.6 14.2 17.1 15.4 14.4 15.2 16.3 20.1 5.0 30.5 10.8 24.1 16.4 21.7 34.8 14.4 44.9 35.9 13.1 18.9 24.2 19.6 19.2 25.0 25.5 45.8 20.8 20.4 48.6 23.3 13.1 43.5 4.1 29.1 6.5 20.8 39.6 5.4 22.2 30.9 10.4 12.2 33.2 21.5 9.6 23.7 24.9 23.0 19.1 22.2 26.8 20.9 7.4 12.3 30.5 18.2 12.8 15.5 0.9 2.7 2.6 3.8 4.0 5.2 3.0 4.3 3.6 2.6 3.7 2.3 4.1 10.9 2.1 7.1 1.7 4.9 1.9 49.3 47.5 22.5 36.7 53.7 36.4 62.3 27.1 41.4 38.8 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;pancreas: 18.3;salivary gland: 19.5;skeletal muscle: 23.7" "Cell line enhanced" "Detected in many" "Daudi: 11.2;Hep G2: 18.4;SCLC-21H: 23.4" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 0.0 0.7 3.9 0.9 3.8 0.0 1.2 9.5 7.2 0.7 7.5 7.4 1.3 1.5 2.1 6.6 0.1 21.9 4.0 4.2 0.0 0.0 0.0 0.0 2.6 0.0 18.3 0.8 7.5 0.9 4.9 4.8 19.5 5.5 23.7 3.0 6.2 1.6 1.1 0.5 3.0 1.5 0.0 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 0.3 0.0 4.4 4.0 2.8 8.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 1.6 0.1 11.2 1.5 0.0 0.2 6.4 0.0 0.0 0.0 7.4 0.0 3.5 18.4 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 5.8 0.1 0.1 7.1 0.2 0.0 0.0 9.1 0.0 0.6 23.4 9.2 1.4 6.3 0.6 0.8 1.3 0.1 0.0 3.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.6;testis: 26.7" "Cell line enhanced" "Detected in some" "AF22: 5.8;AN3-CA: 4.4;HAP1: 6.7;NTERA-2: 11.9;SiHa: 5.8;U-2 OS: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.1;T-cells: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles Vesicles "HPA077678: " "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.9 5.0 3.9 0.9 4.3 0.8 1.7 3.0 3.6 1.5 0.7 1.7 13.9 1.0 1.3 31.6 1.1 1.8 1.1 1.5 3.9 3.4 2.8 8.7 0.9 1.0 2.3 3.0 5.7 0.9 2.2 14.0 1.2 3.9 2.2 0.7 1.3 1.2 4.8 0.7 0.9 0.7 1.5 3.3 1.0 1.2 26.7 3.5 0.0 1.7 0.0 0.8 1.3 1.9 1.1 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.0 5.8 4.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.1 0.2 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.8 0.8 0.0 1.1 0.2 1.9 1.8 5.8 0.0 0.7 0.5 0.0 0.3 0.0 5.2 0.0 1.2 0.0 4.0 0.0 1.6 0.0 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.1 1.9 0.4 0.1 0.1 0.0 0.0 0.0 0.1 3.9 4.3 3.0 3.6 3.9 3.4 2.3 3.0 3.9 3.5 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780678-42796936 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1;ovary: 14.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.4;K-562: 21.7;TIME: 21.0;WM-115: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.1 0.0 0.8 5.8 0.2 0.0 2.6 0.6 0.3 0.7 12.9 0.4 0.4 2.1 0.2 2.8 8.7 0.5 1.0 0.2 2.6 0.0 28.1 0.2 0.4 0.1 0.1 0.3 14.6 1.0 0.0 2.4 0.0 1.7 11.1 11.7 12.2 1.4 1.2 0.0 0.5 3.3 0.4 0.8 0.1 2.6 0.4 0.2 0.0 0.0 0.2 2.0 0.3 0.4 0.4 0.0 0.0 0.3 0.0 1.0 0.0 1.2 0.6 0.2 0.0 0.2 0.1 2.9 7.2 2.8 2.7 0.8 0.4 0.5 0.2 4.3 19.4 0.0 0.1 0.2 4.7 0.4 0.9 0.0 0.0 2.8 4.6 0.0 0.4 2.5 0.4 3.9 1.2 0.2 21.7 0.7 0.0 0.6 0.0 0.5 0.2 4.9 0.3 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.9 1.4 1.5 21.0 0.2 1.9 0.2 0.1 3.5 3.0 0.6 0.0 1.2 14.1 0.0 0.3 0.0 0.0 0.0 0.7 0.4 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.3 2.6 0.0 0.1 0.3 1.7 0.2 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342738-86478420 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favourable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 15.4 9.1 9.7 15.6 14.1 5.2 20.9 8.5 9.5 11.5 16.9 7.5 21.1 8.7 11.9 19.3 11.7 7.2 22.0 40.7 8.7 8.5 16.9 37.2 10.2 15.9 10.0 7.8 10.1 11.3 40.7 7.3 15.6 12.7 17.8 11.3 8.9 11.8 9.4 58.0 13.8 13.0 18.4 9.9 19.1 11.4 10.4 9.5 11.1 11.2 18.0 12.5 14.5 12.3 3.7 2.6 6.5 2.8 2.9 10.4 2.3 22.9 10.8 7.5 5.3 9.4 9.3 6.9 8.4 8.9 6.7 8.0 7.6 14.1 9.9 5.7 14.3 19.7 10.5 13.4 11.6 12.2 8.4 11.3 9.6 17.8 6.9 4.5 5.9 8.4 17.2 7.3 13.6 29.4 5.9 11.6 11.3 11.4 10.8 3.4 4.5 12.2 7.1 9.0 8.7 15.0 17.6 2.2 5.2 8.3 42.1 8.9 12.5 4.2 33.8 10.0 11.9 10.6 4.3 13.8 8.4 10.1 12.4 0.8 7.6 6.5 2.8 4.8 7.2 2.4 6.0 3.7 8.7 7.1 1.9 3.6 10.4 6.3 1.7 2.9 2.8 2.6 8.0 2.3 9.7 14.1 8.5 9.5 8.7 8.5 10.0 7.8 12.7 9.5 WWP2 AIP2 ENSG00000198373 "WW domain containing E3 ubiquitin protein ligase 2" O00308 16 69762306-69941741 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-3)" "unprognostic (2.86e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.14e-1)" "unprognostic (7.50e-2)" "unprognostic (2.08e-2)" "unprognostic (9.81e-2)" "prognostic favourable (5.87e-11)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" 21.8 27.0 18.0 21.5 24.4 31.0 19.1 19.1 29.0 18.9 22.8 29.7 19.6 23.9 31.9 17.2 21.3 23.9 19.3 12.2 18.0 17.4 26.9 14.9 22.7 20.6 20.0 15.9 22.5 27.3 34.1 15.9 24.1 21.7 17.7 20.7 28.1 29.0 19.4 17.6 24.4 25.3 15.3 19.7 26.2 24.1 17.0 18.4 25.2 19.7 14.6 37.7 16.5 17.3 7.1 8.2 28.0 15.5 4.6 9.5 8.1 12.5 12.7 8.3 8.6 7.0 5.9 12.7 8.4 9.8 14.6 15.4 11.7 9.7 14.6 9.2 14.8 15.0 10.9 12.7 11.1 6.8 9.4 8.1 7.8 20.2 13.2 14.3 12.1 8.6 9.5 19.9 13.9 13.4 12.3 8.3 9.3 22.2 7.8 16.0 11.6 5.7 17.6 7.0 24.8 14.2 12.2 10.3 11.3 36.0 10.4 7.7 16.2 17.7 13.3 11.4 16.8 15.9 10.1 19.2 12.8 22.1 12.3 12.2 20.1 18.2 10.0 15.6 9.5 12.9 7.3 6.4 7.1 7.6 8.2 7.1 7.5 5.1 28.0 4.6 15.5 4.0 6.3 8.1 18.0 24.4 19.1 29.0 18.0 17.4 20.0 15.9 21.7 18.4 ZC3HAV1 "FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2" ENSG00000105939 "Zinc finger CCCH-type containing, antiviral 1" Q7Z2W4 7 139043520-139109719 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047818, HPA059096" Approved Supported "Golgi apparatus,Cytosol" Cytosol "Golgi apparatus" "HPA047818: AB_10962642, HPA059096: " "unprognostic (1.68e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-2)" "unprognostic (3.92e-1)" "unprognostic (2.61e-2)" "prognostic unfavourable (8.77e-7)" "unprognostic (5.40e-2)" "unprognostic (3.08e-1)" "unprognostic (2.55e-2)" "unprognostic (3.72e-1)" "unprognostic (5.41e-2)" "unprognostic (3.31e-3)" "prognostic favourable (6.86e-4)" "unprognostic (6.47e-2)" "unprognostic (1.99e-1)" "unprognostic (7.84e-2)" 14.3 14.8 6.8 19.8 6.6 52.6 13.8 1.6 5.6 11.2 11.5 6.7 10.8 6.9 10.0 10.9 14.2 9.5 10.4 7.0 5.4 7.2 11.2 13.1 17.2 44.4 7.5 4.0 10.6 11.0 9.8 11.4 8.5 8.6 11.2 10.2 9.3 16.9 11.5 3.8 9.5 14.8 10.8 9.0 22.6 9.6 7.8 6.9 43.9 18.2 8.8 26.1 10.8 29.0 16.3 7.0 28.8 11.9 15.6 27.9 11.8 11.4 14.2 2.0 11.8 18.7 18.0 8.6 13.0 10.0 22.7 23.4 10.1 14.9 10.1 12.2 20.7 13.0 15.8 15.4 12.9 17.9 5.9 20.0 14.4 12.5 10.8 23.2 18.6 18.3 9.9 25.8 5.8 16.9 16.9 11.3 9.7 10.8 19.1 27.1 8.0 8.6 22.7 7.1 9.7 15.6 14.5 3.6 7.5 20.0 14.1 17.3 8.2 14.5 21.2 4.8 7.1 13.2 10.7 8.7 9.1 23.7 10.9 21.7 11.4 28.8 8.2 11.9 19.4 10.6 24.6 14.3 27.9 23.5 6.4 16.3 27.3 26.4 22.1 15.6 11.9 7.0 24.2 11.8 6.8 6.6 1.6 5.6 5.4 7.2 7.5 4.0 8.6 6.9 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999030-75110994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.1" "Cell line enhanced" "Detected in many" "HMC-1: 53.8;MOLT-4: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.5;T-reg: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;monocytes: 1.4;T-cells: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favourable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 10.0 9.5 13.4 8.1 13.7 5.2 16.6 6.3 16.5 13.2 12.5 8.1 6.7 8.3 10.7 9.1 28.2 10.0 11.3 9.1 11.6 14.6 5.6 12.8 12.8 8.7 9.1 9.4 10.1 6.1 12.2 6.2 9.7 7.8 9.1 10.8 7.2 7.5 7.5 58.6 14.5 11.2 10.1 8.8 2.8 11.8 21.6 4.9 80.1 21.4 16.9 13.3 14.0 15.5 0.2 0.8 4.5 1.4 0.0 5.2 0.3 3.1 4.6 8.0 8.2 8.6 6.7 27.7 3.8 5.4 5.3 5.2 7.4 9.9 0.8 3.0 8.3 7.6 3.9 5.3 4.2 7.7 2.2 16.5 1.5 13.6 6.8 7.9 53.8 6.0 4.4 5.5 4.5 8.6 7.9 2.6 4.1 30.2 38.5 29.1 11.1 5.0 17.1 3.0 5.0 7.5 9.0 10.7 11.5 6.1 8.1 2.2 21.5 7.5 5.8 3.7 6.4 6.5 2.3 15.4 15.6 9.1 4.8 8.8 3.7 4.5 1.4 0.9 0.2 1.1 1.3 0.2 1.5 0.2 0.8 0.0 0.0 0.2 1.2 0.0 1.1 0.0 5.2 0.3 13.4 13.7 6.3 16.5 11.6 14.6 9.1 9.4 7.8 4.9 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284307-30367692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 5.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved "HPA072244: " "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavourable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favourable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favourable (8.71e-4)" "unprognostic (8.67e-2)" 7.8 8.0 10.0 9.3 10.6 9.7 16.2 12.8 10.0 5.8 16.1 10.5 7.6 11.3 7.7 9.7 14.2 5.2 8.7 8.4 9.6 6.1 19.3 24.0 7.9 12.0 10.0 7.4 5.8 14.0 8.0 9.9 9.6 11.0 7.0 14.3 5.8 10.5 13.7 17.5 11.5 12.7 8.3 10.5 9.2 12.4 20.6 9.1 7.9 13.3 9.8 10.9 9.4 11.8 1.3 5.8 1.4 1.1 0.7 2.4 0.5 6.6 2.4 2.0 1.7 2.3 1.6 10.5 2.5 2.6 2.8 3.9 1.2 11.2 7.0 6.7 2.0 6.5 6.6 4.3 3.1 6.8 6.0 4.3 5.2 3.2 1.2 3.3 8.3 2.5 7.4 1.9 4.8 2.3 5.3 14.0 3.0 2.5 6.8 8.9 4.6 3.0 5.9 4.3 11.9 8.6 14.4 6.9 6.5 5.1 21.7 4.3 5.8 13.6 2.6 2.8 4.8 2.6 5.3 24.0 20.5 9.1 3.0 7.3 4.0 0.5 0.9 1.1 1.0 0.9 1.5 1.3 1.2 1.4 0.8 0.8 0.7 1.1 1.4 0.7 1.1 5.8 2.4 0.5 10.0 10.6 12.8 10.0 9.6 6.1 10.0 7.4 11.0 9.1 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827835-186849208 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.4" "Cell line enhanced" "Detected in some" "HSkMC: 1.1;U-138 MG: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "unprognostic (2.00e-1)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.1 0.4 0.0 0.0 0.3 0.0