Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713946-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 20.1 11.6 12.4 15.0 18.1 10.7 22.0 6.7 16.0 28.9 34.3 29.1 12.1 11.9 26.6 16.9 21.4 20.8 30.9 14.2 10.3 8.4 9.9 6.7 13.8 8.7 24.1 9.4 24.2 12.2 27.7 14.5 13.6 17.1 27.3 15.8 19.4 14.6 18.0 10.8 14.2 17.0 66.6 14.3 10.8 21.9 9.8 21.2 5.8 19.5 11.4 9.1 35.8 31.9 3.1 3.1 1.1 5.0 2.4 2.6 1.6 7.0 15.7 16.9 20.4 24.8 30.3 6.2 12.4 19.5 14.6 12.4 12.3 9.2 11.6 7.2 16.5 13.7 8.5 11.5 10.8 7.3 5.3 7.6 26.9 10.5 16.9 11.7 10.7 22.1 12.7 26.1 16.2 20.2 42.6 9.3 17.8 13.4 14.8 9.6 18.7 11.6 17.2 21.9 12.6 14.7 8.3 15.8 19.7 20.8 8.1 10.0 15.9 10.8 23.1 56.0 14.5 21.4 19.5 2.8 6.6 15.6 23.1 9.7 17.7 0.2 2.1 1.1 2.0 1.2 2.6 3.1 2.0 1.9 2.0 1.4 1.9 1.7 0.2 2.4 5.0 3.1 0.9 1.6 12.4 18.1 6.7 16.0 10.3 8.4 24.1 9.4 17.1 21.2 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099327-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 31.7;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Supported Nucleoplasm Nucleoplasm "CAB017106: , HPA001866: AB_1078082, HPA072754: " "unprognostic (3.05e-1)" "prognostic unfavourable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavourable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavourable (8.40e-4)" 14.3 5.2 8.6 7.4 13.7 3.7 8.3 14.9 10.6 9.2 6.6 5.8 4.5 4.0 5.4 4.7 3.9 4.3 18.8 6.8 9.7 3.9 4.9 4.3 11.5 3.7 6.5 6.1 5.6 8.4 9.2 8.4 6.1 8.1 5.1 5.2 5.8 4.5 4.4 5.2 6.6 3.7 6.9 6.2 3.9 4.7 9.2 8.6 3.6 5.8 3.1 3.6 6.7 11.2 2.8 2.0 3.8 1.2 1.8 2.2 0.6 10.0 5.5 3.7 2.5 3.2 7.3 2.3 11.1 9.1 13.7 9.9 4.0 3.1 5.8 8.2 7.9 5.0 5.2 3.7 19.4 3.6 4.8 2.8 5.0 2.0 5.8 3.1 0.9 6.7 4.9 19.4 31.7 15.1 6.6 1.7 17.7 2.6 2.4 1.6 3.6 1.8 3.7 6.2 2.8 4.6 1.6 2.3 5.1 9.2 2.9 22.8 2.6 2.6 29.5 14.2 10.6 6.8 17.8 3.1 3.8 6.0 6.7 1.7 13.7 3.8 1.2 0.4 2.2 0.4 1.0 1.8 1.4 1.4 0.9 2.8 1.9 2.0 2.6 1.8 0.5 2.0 0.8 0.6 8.6 13.7 14.9 10.6 9.7 3.9 6.5 6.1 8.1 8.6 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol 3700000 Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavourable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 22.3 59.7 38.0 20.8 40.3 38.0 33.0 27.9 43.7 23.1 29.7 27.4 24.4 31.1 25.2 36.2 24.8 29.5 26.9 27.4 34.6 33.7 42.1 54.8 24.7 29.4 31.5 34.6 33.7 53.0 28.4 43.9 39.7 39.7 27.0 32.8 28.5 46.0 23.8 35.4 21.6 34.5 24.2 28.6 28.1 34.2 38.3 21.2 33.0 32.5 32.8 29.8 22.7 20.3 33.9 20.3 17.3 23.0 35.3 41.0 33.1 17.6 26.4 41.1 22.6 18.7 18.7 33.5 21.5 22.9 21.5 19.1 36.1 17.8 11.1 16.8 20.1 17.4 39.9 23.3 19.4 27.0 40.7 32.5 23.9 79.1 25.9 36.9 18.7 19.0 21.3 20.1 24.9 24.4 32.8 21.7 25.4 24.0 39.7 35.7 49.7 29.8 26.3 41.8 25.4 33.6 25.3 44.9 44.5 13.4 31.7 43.0 18.8 19.8 20.1 23.7 15.8 19.5 32.4 29.5 58.6 34.7 28.1 32.0 27.9 17.3 19.8 17.1 30.1 22.7 39.7 33.9 34.3 34.4 17.7 31.1 41.0 39.7 3.5 35.3 23.0 20.3 35.6 33.1 38.0 40.3 27.9 43.7 34.6 33.7 31.5 34.6 39.7 21.2 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 15.7;HEL: 11.3;HMC-1: 12.7;Karpas-707: 17.3;U-266/70: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB001701: , HPA036961: " "prognostic favourable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 14.3 8.5 2.3 10.9 4.6 2.5 14.8 1.2 2.4 7.1 6.2 4.7 14.6 1.9 7.9 6.2 5.0 5.4 6.6 8.4 2.3 2.4 5.1 5.5 17.4 18.9 3.7 2.7 3.6 11.9 8.1 2.8 23.0 4.0 6.3 3.9 6.8 6.5 14.5 19.7 3.1 6.4 8.8 4.7 13.6 5.1 4.1 3.6 5.3 7.4 5.8 12.0 7.1 6.9 8.2 8.0 13.3 13.0 3.4 9.6 4.9 1.5 2.0 0.4 0.0 1.7 1.9 0.0 1.4 0.3 1.2 1.6 0.6 1.3 0.4 0.6 2.1 0.1 1.4 0.0 1.1 15.7 0.1 11.3 0.2 0.0 2.7 0.0 12.7 2.8 0.0 0.6 0.0 4.9 1.0 17.3 7.4 0.5 0.0 2.7 4.7 3.9 0.0 5.6 0.7 0.7 0.6 0.3 0.0 0.0 0.1 4.2 3.0 7.0 4.0 0.0 0.8 3.1 0.3 16.9 3.7 0.0 2.1 0.0 3.1 7.8 13.0 13.3 0.6 12.0 0.6 8.2 1.4 1.3 8.0 4.9 0.2 0.6 0.4 3.4 9.2 7.0 9.6 4.9 2.3 4.6 1.2 2.4 2.3 2.4 3.7 2.7 4.0 3.6 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921566 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1;pituitary gland: 17.9" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 26.4" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 1.8 3.1 3.6 1.2 4.4 0.3 1.1 0.5 8.1 0.7 2.1 2.0 0.0 0.7 0.5 0.5 0.6 0.5 1.2 0.4 3.4 4.9 0.4 0.5 1.1 0.5 2.7 4.2 0.6 0.4 0.4 17.9 0.5 5.5 0.5 1.2 2.4 0.9 0.8 0.3 0.9 1.5 0.9 2.1 0.5 0.8 4.9 0.9 0.0 1.6 0.0 0.3 0.6 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.5 0.0 0.0 0.1 0.3 26.4 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 4.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 4.4 0.5 5.9 3.4 4.9 2.7 4.2 5.5 0.9 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219203-41261766 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 66.1;U-251 MG: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 8.8;plasmacytoid DC: 18.3" "Group enriched" "Detected in many" 14 "dendritic cells: 18.3;NK-cells: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" 61000000 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: , HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavourable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 38.0 15.4 10.6 11.7 12.7 1.3 27.1 6.3 12.1 26.2 26.8 13.4 8.1 9.1 28.0 19.4 21.8 17.4 17.8 18.5 11.5 6.1 7.8 13.0 20.0 7.6 10.6 9.3 20.9 5.1 9.6 5.6 26.6 10.1 19.5 10.2 16.8 7.8 20.4 14.1 13.8 12.8 29.4 10.7 27.3 16.2 22.4 10.4 3.4 12.0 8.4 5.8 35.6 18.3 0.1 18.3 0.9 0.2 8.8 0.3 0.2 52.5 21.2 1.3 0.1 4.8 4.8 0.0 41.8 37.6 61.4 38.1 1.1 24.7 0.0 17.0 66.1 4.4 0.0 28.1 52.9 0.0 0.0 0.0 14.0 0.8 17.4 0.0 0.0 3.6 0.5 36.2 56.2 22.7 2.0 0.0 38.0 0.0 0.0 0.0 0.5 10.2 0.0 22.4 0.0 27.4 0.0 0.0 0.0 10.8 0.0 0.2 0.1 0.9 46.6 43.5 29.7 41.5 70.8 0.0 0.1 0.1 29.0 0.0 32.3 0.9 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.1 4.2 0.1 0.2 0.2 0.3 8.8 0.1 18.3 0.2 0.2 10.6 12.7 6.3 12.1 11.5 6.1 10.6 9.3 10.1 10.4 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564604 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "blood: 47.8;intestine: 23.5;lymphoid tissue: 39.8" "Cell line enhanced" "Detected in some" "Daudi: 43.0;REH: 11.6;RPMI-8226: 14.2;U-698: 21.0;U-87 MG: 8.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 47.8;naive B-cell: 33.9" "Lineage enriched" "Detected in many" 5 "B-cells: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005093, HPA069571" Approved Approved Nucleoplasm Nucleoplasm "CAB005093: AB_2274756, HPA069571: " "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.2 0.1 32.3 0.1 1.7 0.2 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.0 1.9 0.2 0.4 0.3 0.1 0.1 1.3 0.5 0.6 27.6 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.3 2.4 0.0 0.1 0.1 23.5 0.0 0.1 31.9 1.4 0.2 0.0 3.9 0.7 0.4 39.8 2.5 0.4 47.8 4.3 0.1 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.6 0.0 14.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 3.7 21.0 8.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 9.8 47.8 0.3 1.1 0.0 33.9 0.2 0.1 0.1 0.0 0.0 4.3 0.4 1.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 57.1" "Cell line enriched" "Detected in single" 121 "HUVEC TERT2: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 8.2 0.3 0.1 1.0 0.7 3.6 5.4 0.1 0.3 2.2 5.5 0.1 4.6 2.4 2.6 57.1 1.5 2.5 2.6 10.5 0.5 0.0 0.2 0.9 3.7 6.5 0.4 0.0 1.4 0.9 0.2 0.6 2.6 0.7 2.2 1.4 0.5 1.5 0.6 4.2 1.6 5.5 2.2 0.4 2.4 1.5 1.9 0.1 0.2 2.2 1.1 0.8 2.8 2.4 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.5 0.0 0.4 0.0 0.7 0.1 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 77.5;lymphoid tissue: 37.0" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HEL: 40.0;HMC-1: 144.1;U-937: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 77.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" 610000 "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 7.3 2.4 3.3 23.5 5.6 14.0 2.6 0.8 3.6 2.3 3.0 4.7 0.3 2.2 1.9 2.6 2.4 2.0 3.7 3.3 3.3 2.5 2.2 2.5 10.7 25.1 5.4 1.2 1.2 1.5 0.2 1.4 3.2 4.1 2.5 4.5 1.5 3.2 1.0 1.0 2.5 12.9 3.3 10.8 37.0 3.1 1.3 6.3 4.0 1.7 1.8 36.7 5.8 2.0 13.7 13.2 77.5 20.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.0 0.0 16.0 144.1 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.0 0.0 0.0 11.2 0.2 0.0 12.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 13.7 0.0 20.9 0.0 77.5 11.3 19.3 0.0 18.1 0.0 13.7 0.0 0.0 13.2 13.7 0.0 0.0 4.5 0.0 20.7 6.0 0.0 6.1 3.3 5.6 0.8 3.6 3.3 2.5 5.4 1.2 4.1 6.3 CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "K-562: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" 6.2 2.4 5.8 6.5 5.5 13.7 12.2 1.8 6.2 7.7 11.8 4.8 2.2 7.2 15.1 4.8 3.4 13.7 3.6 4.1 8.8 3.5 6.6 2.4 12.3 15.4 3.8 5.4 5.8 6.7 9.8 8.1 7.6 4.6 10.0 6.3 8.3 7.7 3.9 4.3 5.6 22.6 5.0 3.2 9.6 6.0 38.2 4.7 12.0 6.1 3.4 11.3 5.8 8.4 4.8 6.1 11.6 3.7 3.9 13.0 4.1 2.2 1.8 5.8 6.5 2.1 1.6 4.0 2.8 1.9 2.8 2.3 6.1 1.9 1.1 2.1 1.7 1.7 3.9 1.6 2.9 2.2 9.7 3.9 1.7 1.9 0.8 5.2 7.0 1.3 0.4 3.0 1.0 4.9 30.0 3.4 4.1 0.9 4.2 5.9 3.5 2.3 4.6 7.5 1.1 1.9 5.0 1.0 1.8 3.0 2.9 3.9 1.3 6.8 2.1 1.6 3.5 2.6 1.6 1.7 0.6 1.7 1.9 4.9 0.9 11.6 3.7 8.4 7.3 3.3 13.0 4.8 11.3 8.4 3.5 3.1 11.0 5.8 5.5 3.9 2.3 6.1 5.6 4.1 5.8 5.5 1.8 6.2 8.8 3.5 3.8 5.4 4.6 4.7 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619830 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 15.1;ASC TERT1: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.9" "Lineage enhanced" "Detected in many" "granulocytes: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013312, HPA064747" Approved Supported Nucleoplasm Nucleoplasm "HPA013312: AB_1846354, HPA064747: " "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favourable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (7.40e-2)" 7.3 6.2 6.8 3.0 7.5 4.4 15.7 2.4 6.6 5.3 5.0 14.8 7.1 4.5 4.0 3.7 3.5 7.1 5.9 8.2 6.0 4.6 9.1 16.0 4.9 1.8 9.5 4.0 5.8 7.3 17.1 5.2 3.4 7.1 5.7 5.4 8.3 3.8 7.2 2.2 3.3 7.7 4.2 9.3 2.2 9.3 16.9 8.2 0.2 13.6 2.2 2.1 10.4 10.3 1.6 0.0 9.9 0.0 0.1 2.9 0.8 5.1 2.9 3.1 3.2 15.1 22.7 8.5 3.8 5.0 2.5 4.1 9.9 8.3 0.0 3.7 8.0 5.8 4.4 3.0 3.0 1.3 4.1 0.8 1.0 7.7 2.4 0.0 0.1 9.3 1.5 2.7 2.5 0.5 3.0 0.6 3.5 2.5 0.0 0.8 5.8 2.5 0.0 1.9 0.1 4.0 8.0 0.9 4.9 2.6 0.8 1.5 0.7 1.7 1.5 2.5 3.0 6.5 2.7 0.1 0.0 0.0 2.7 0.0 6.0 9.9 0.0 3.1 2.9 0.0 1.6 1.6 1.3 2.3 0.0 0.8 2.3 1.4 0.0 0.1 0.0 0.0 1.6 0.8 6.8 7.5 2.4 6.6 6.0 4.6 9.5 4.0 7.1 8.2 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188402 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 23.0;testis: 19.4" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005855 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA005855: AB_1846364" "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.8 1.2 1.1 5.5 1.1 13.0 0.8 0.7 1.2 1.1 3.3 0.6 1.0 1.8 0.6 0.9 3.9 0.4 2.2 0.7 1.3 2.4 1.2 0.9 0.7 4.1 1.4 0.2 2.1 3.6 0.4 2.3 4.2 1.2 1.0 4.0 1.5 1.8 0.5 0.7 0.8 2.1 0.8 0.7 3.6 1.3 19.4 0.2 23.0 1.6 8.8 7.4 0.8 1.3 1.7 0.9 0.5 0.1 0.0 1.0 0.1 7.5 3.7 17.8 9.6 0.6 1.2 12.3 10.5 4.0 13.2 10.7 16.1 3.9 22.4 4.1 2.7 5.7 30.5 7.2 13.9 7.3 16.0 28.7 6.8 7.9 0.6 20.2 8.3 0.6 1.1 16.4 7.1 5.0 22.8 11.9 7.1 4.0 25.2 15.7 26.0 8.5 11.3 11.7 12.2 3.3 7.1 8.4 10.4 6.5 7.6 3.3 4.0 14.3 2.5 6.5 10.0 7.2 14.2 6.0 17.9 35.2 4.8 22.5 5.4 0.0 0.0 0.5 0.4 0.0 0.0 1.7 0.6 0.2 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.5 0.0 0.1 1.1 1.1 0.7 1.2 1.3 2.4 1.4 0.2 1.2 0.2 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 4.5;NK-cells: 9.3;T-cells: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Supported "Vesicles,Mitotic spindle" Vesicles "Mitotic spindle" "HPA038892: , HPA038893: , HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavourable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavourable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 12.1 8.7 15.1 27.7 23.3 26.0 28.8 49.6 21.1 13.0 14.7 12.8 4.6 14.9 17.0 10.3 11.7 13.0 18.6 7.5 15.7 12.5 13.3 11.0 33.0 42.8 21.9 12.5 17.3 5.7 7.5 21.0 30.3 13.8 11.0 12.0 7.7 7.4 10.2 6.2 19.8 16.8 14.8 14.7 24.5 14.1 6.3 22.3 33.3 18.7 20.8 31.6 15.3 16.3 4.5 1.3 1.5 1.8 9.3 15.5 5.9 29.8 64.5 8.6 14.3 10.6 10.4 4.3 14.8 22.2 24.8 18.5 11.2 43.3 20.8 6.4 15.1 43.7 11.7 24.6 11.7 8.0 12.6 11.2 20.7 13.5 42.3 8.7 5.8 10.2 19.8 23.0 27.2 13.7 7.2 55.1 14.6 24.0 27.1 12.7 6.4 27.6 14.2 24.4 14.9 16.9 2.8 6.2 13.5 35.1 33.5 17.2 11.3 4.5 11.3 13.3 16.1 24.1 19.6 13.4 21.2 8.4 6.8 8.6 12.8 1.5 1.4 0.0 13.6 1.8 12.7 3.5 13.6 13.7 1.3 4.5 11.4 13.2 0.1 9.3 0.9 0.7 15.5 5.9 15.1 23.3 49.6 21.1 15.7 12.5 21.9 12.5 13.8 22.3 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285265-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 23.3;testis: 22.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 2.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003800, HPA066991" Approved Supported "Nuclear speckles" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: " "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favourable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavourable (3.03e-6)" "prognostic unfavourable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 1.1 0.6 0.3 6.7 0.4 5.2 1.1 0.4 0.6 0.6 3.3 0.1 0.7 3.0 0.3 0.6 2.5 0.2 0.4 0.7 0.4 0.4 0.4 0.6 0.7 2.6 0.4 0.3 0.3 0.3 0.0 0.4 1.9 0.3 0.4 4.0 0.0 1.2 0.7 0.2 1.1 3.7 0.5 0.3 1.7 1.2 22.3 0.2 23.3 0.3 1.8 5.0 0.6 0.9 1.0 0.1 0.7 0.0 2.1 2.7 0.5 13.5 5.6 19.0 14.6 0.4 1.9 4.8 8.1 8.8 18.6 25.7 13.6 26.3 6.3 6.9 4.9 7.3 15.6 12.5 18.0 5.2 10.7 4.8 7.7 10.1 0.1 3.2 4.9 0.4 0.5 11.0 9.0 11.9 7.0 12.4 11.3 7.4 8.8 8.1 4.9 6.2 5.8 17.3 7.3 3.2 4.1 9.6 5.9 18.3 5.6 8.7 9.3 6.7 3.6 10.3 8.7 7.1 13.0 7.6 6.2 6.2 4.1 6.9 7.8 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.5 0.3 0.0 0.2 0.0 0.0 0.7 2.1 0.0 0.1 2.7 0.5 0.3 0.4 0.4 0.6 0.4 0.4 0.4 0.3 0.3 0.2 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: " "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavourable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavourable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.8 21.5 16.5 16.4 2.7 3.3 9.5 13.4 19.7 28.5 31.6 16.1 27.9 27.5 9.8 20.8 41.2 25.0 16.2 53.3 32.9 12.1 14.0 15.4 26.7 2.0 17.5 10.0 1.2 1.0 17.8 31.0 18.1 7.0 35.3 34.2 39.8 24.0 14.2 5.8 46.6 14.9 14.5 5.9 15.1 12.3 6.7 8.6 24.4 14.5 10.7 30.0 14.9 6.6 12.7 43.4 19.9 31.6 8.5 9.8 18.9 21.2 25.2 23.1 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 CHMP4A "C14orf123, HSPC134, VPS32A" ENSG00000254505 "Charged multivesicular body protein 4A" Q9BY43 14 24209583-24213869 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068473 Approved 2600000 "HPA068473: " "unprognostic (4.33e-3)" "unprognostic (3.76e-2)" "unprognostic (4.29e-2)" "unprognostic (5.45e-2)" "unprognostic (4.29e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-4)" "unprognostic (2.02e-3)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavourable (3.91e-8)" "unprognostic (3.30e-1)" "unprognostic (3.42e-1)" "unprognostic (7.37e-2)" "unprognostic (6.90e-2)" 31.6 24.7 37.0 25.1 36.5 21.0 24.2 11.6 28.2 18.6 32.3 23.8 23.6 20.8 18.8 34.5 30.0 22.3 21.5 24.6 29.9 26.7 24.4 26.2 19.3 36.5 39.8 26.6 16.0 23.6 36.9 14.5 18.8 34.2 26.1 32.6 16.8 25.3 32.4 26.3 26.8 22.5 42.7 35.4 28.9 24.7 9.8 28.9 27.5 21.7 15.5 42.7 32.0 24.2 41.8 45.1 30.1 44.3 30.8 41.8 35.9 10.9 19.9 9.4 9.7 10.1 10.9 15.0 13.1 11.2 9.7 11.5 9.6 23.7 19.0 11.8 14.0 11.2 9.7 17.8 9.9 35.3 5.5 15.4 19.0 39.4 25.2 24.4 16.3 12.2 21.7 8.0 29.6 15.3 15.6 25.5 19.6 23.7 23.6 18.4 6.4 18.4 16.3 9.2 17.8 15.5 26.9 6.3 8.0 30.1 17.8 14.4 13.2 17.6 12.3 5.3 8.9 9.1 10.0 27.5 33.5 22.1 6.0 16.6 12.6 30.1 37.0 24.4 31.9 44.3 33.5 41.8 34.2 35.1 42.3 37.3 27.4 28.6 11.3 30.8 41.8 45.1 41.8 35.9 37.0 36.5 11.6 28.2 29.9 26.7 39.8 26.6 34.2 28.9 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: " "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favourable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.1 6.1 10.3 3.1 11.7 12.9 8.1 8.8 12.6 9.0 12.0 11.4 5.3 2.8 6.0 5.5 8.8 13.0 4.1 18.5 12.4 11.4 8.3 15.5 14.1 7.0 8.7 14.2 5.9 18.6 11.3 19.9 5.2 10.0 36.8 12.8 5.5 10.2 26.4 6.5 14.0 10.4 12.2 14.6 6.2 5.3 10.4 8.2 7.7 2.9 12.8 2.4 6.0 8.0 10.1 6.9 9.7 9.7 21.7 9.0 6.5 6.5 7.1 6.8 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA055366: , HPA059507: " "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavourable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favourable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 6.0 5.2 18.9 5.8 9.5 5.1 16.1 5.4 6.6 4.2 4.2 5.5 4.3 13.1 7.5 3.7 8.7 9.4 7.0 4.0 9.5 7.4 10.4 5.4 7.0 8.2 12.9 10.5 4.1 6.4 6.1 12.3 7.3 14.6 9.1 6.3 10.4 8.8 7.7 12.3 7.4 9.8 11.4 14.1 10.6 13.5 9.0 12.8 2.0 6.5 5.0 9.9 15.9 4.8 2.6 6.9 4.7 4.5 17.4 14.8 11.9 5.1 9.3 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavourable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavourable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.5 14.8 15.3 24.2 21.9 26.9 19.2 14.8 20.4 11.3 13.6 15.8 35.0 14.7 14.3 28.9 19.1 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.3 28.7 24.0 23.9 12.1 14.9 12.7 15.8 19.8 22.7 12.0 10.0 16.1 9.0 13.3 17.0 16.2 10.6 12.4 12.2 13.6 13.5 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.4 19.6 16.7 11.4 33.0 16.3 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" "Actin filaments" "HPA043746: " "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.8 6.3 5.9 8.5 17.6 14.8 9.7 6.7 7.6 4.0 7.4 6.7 5.5 3.9 5.4 2.8 9.1 7.5 5.4 6.6 14.1 5.9 1.5 11.9 8.2 6.6 3.1 5.0 6.7 7.9 6.4 8.7 2.7 3.5 11.7 5.1 2.8 4.0 11.4 3.0 3.9 4.0 5.2 5.7 4.0 2.1 6.6 4.4 7.5 4.1 6.9 4.3 6.6 5.6 8.2 3.0 4.2 7.1 7.7 2.9 3.0 5.9 7.6 4.2 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 82.5;lymphoid tissue: 82.6" "Group enriched" "Detected in some" 5 "BEWO: 50.6;SK-BR-3: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 60.7;non-classical monocyte: 82.5" "Lineage enriched" "Detected in many" 4 "monocytes: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" 1500000000 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavourable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 20.9 12.4 18.2 28.1 18.9 1.8 7.7 2.8 13.5 9.3 8.3 25.4 1.1 9.2 5.9 13.1 8.4 7.9 16.1 8.7 16.4 13.7 7.8 15.1 13.7 25.4 21.3 6.0 5.3 5.2 5.9 6.4 52.1 17.1 8.5 8.4 16.8 8.0 8.7 3.0 5.8 14.5 16.2 25.8 82.6 9.0 4.9 23.0 3.1 4.2 2.9 8.2 16.4 4.7 0.0 19.1 2.9 82.5 0.0 0.1 13.9 1.7 0.0 0.0 0.0 0.8 0.2 50.6 0.1 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 19.3 0.0 0.0 7.2 0.0 0.3 0.0 0.0 1.3 0.0 0.1 0.0 2.6 0.9 0.0 0.4 18.1 0.5 0.1 60.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 2.9 0.0 82.5 1.4 0.0 13.9 18.2 18.9 2.8 13.4 16.4 13.7 21.3 6.0 17.1 23.0 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Approved Vesicles,Cytosol 1500000 "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favourable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favourable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavourable (1.74e-4)" "prognostic favourable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 9.3 8.0 9.5 39.3 11.0 19.9 12.6 18.7 13.4 12.1 13.5 11.8 7.3 16.1 13.9 6.4 33.3 10.6 11.2 14.0 9.8 8.5 8.0 20.9 15.6 67.2 11.1 7.4 10.5 6.7 6.6 10.4 8.8 12.2 9.8 8.9 9.8 13.2 7.0 8.7 14.9 26.2 8.5 10.9 62.7 13.1 8.1 10.6 62.7 8.1 9.5 47.4 17.4 13.2 35.6 22.8 49.6 46.8 16.3 30.7 19.9 12.7 18.0 8.8 14.5 8.4 6.5 7.6 8.6 8.2 16.3 11.6 16.4 11.8 57.1 11.4 7.7 13.3 18.5 17.3 4.6 27.6 22.8 48.3 6.6 16.5 11.7 25.2 61.6 9.2 8.5 11.6 10.4 12.3 13.9 19.9 9.7 21.5 18.1 14.9 10.9 12.9 20.1 7.6 41.6 7.5 28.4 14.7 10.2 11.1 23.4 14.8 16.1 37.2 10.6 19.8 10.4 15.5 14.8 10.7 21.5 58.3 10.2 48.2 13.3 20.7 19.7 49.6 23.4 42.4 20.0 29.4 20.3 23.1 22.8 35.6 15.7 18.4 39.1 16.3 46.8 13.2 30.7 19.9 9.5 11.0 18.7 13.4 9.8 8.5 11.1 7.4 12.2 10.6 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 31.2;HBEC3-KT: 24.0;RT4: 31.9;T-47d: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" 2100000 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favourable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 6.7 11.3 23.5 7.9 36.2 2.2 12.5 6.8 42.2 9.7 25.2 57.4 17.6 16.8 7.7 10.5 30.5 31.7 18.9 8.7 27.8 20.8 19.8 3.5 13.2 3.1 55.7 19.8 11.3 20.9 28.2 14.6 13.3 34.7 17.7 14.9 4.0 28.3 20.5 9.1 41.3 32.1 3.1 43.2 5.1 52.2 5.1 37.0 8.7 20.9 10.5 7.6 16.3 16.6 1.8 0.4 0.0 0.2 0.0 1.8 0.9 19.3 6.4 9.1 1.9 0.6 0.8 5.6 0.5 0.1 0.2 0.0 8.6 10.3 0.1 10.8 1.7 31.2 1.9 24.0 0.1 10.7 3.4 0.0 5.8 2.2 1.8 0.0 0.4 1.2 12.4 0.1 0.2 0.7 5.6 0.2 1.3 12.2 0.6 0.0 1.5 1.3 1.3 6.8 0.7 4.6 31.9 1.6 0.8 1.8 14.4 7.0 35.8 0.2 1.4 4.5 4.2 0.4 4.5 0.2 0.0 0.8 2.9 0.0 3.9 0.0 0.2 0.0 1.1 0.0 0.8 0.4 0.2 0.7 0.4 1.8 1.2 1.8 0.0 0.0 0.0 0.4 0.0 0.9 23.5 36.2 6.8 25.0 27.8 20.8 55.7 19.8 34.7 37.0 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787400 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 60.6;ASC TERT1: 59.9;BJ hTERT+: 44.3;fHDF/TERT166: 31.7;HSkMC: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 5 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Supported "Plasma membrane,Actin filaments" 850000 "Plasma membrane, Actin filaments" "HPA070112: " "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 42.1 43.5 4.7 10.9 6.9 0.2 15.6 7.9 7.1 30.3 30.4 9.0 18.6 3.3 24.2 17.7 25.0 13.4 16.6 15.4 7.9 4.7 4.0 3.3 8.9 5.1 12.9 3.4 26.4 2.2 2.1 4.0 6.6 12.7 21.8 9.1 30.7 6.4 19.3 5.2 6.1 10.1 34.3 19.7 3.4 14.1 8.3 7.5 0.0 8.6 12.8 4.1 29.0 18.3 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 16.0 60.6 59.9 0.2 23.6 44.3 10.3 14.9 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 14.1 12.7 0.1 0.0 0.0 0.0 26.3 0.0 0.0 42.5 0.1 18.2 0.4 11.8 0.1 5.0 9.4 0.0 0.0 0.0 0.1 0.1 0.0 6.7 0.1 0.0 0.0 0.0 9.7 0.0 0.0 0.8 0.0 0.0 0.6 16.5 3.6 8.3 3.2 0.7 1.3 0.0 14.9 0.0 16.7 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 4.7 6.9 7.9 7.1 7.9 4.7 12.9 3.4 12.7 7.5 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.4" "Cell line enhanced" "Detected in many" "HDLM-2: 20.9;HEL: 55.8;K-562: 21.7" "Cancer enhanced" "Detected in many" "glioma: 5.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: " "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favourable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 2.1 12.1 18.6 2.2 28.5 5.0 2.0 24.2 91.4 2.2 2.8 26.9 0.0 2.3 1.9 1.8 1.7 2.4 2.3 9.0 25.0 26.7 8.5 1.6 2.7 1.6 28.8 23.8 1.9 3.4 2.1 7.5 8.0 40.5 2.5 3.0 2.2 1.7 2.1 1.6 2.1 2.3 2.2 28.7 3.2 2.9 3.2 21.1 0.0 3.0 0.0 1.7 1.8 0.6 0.5 0.5 0.0 0.0 0.6 1.5 0.3 3.5 0.9 0.0 1.6 0.7 0.2 8.3 7.0 11.4 11.5 11.3 0.9 0.1 3.3 0.6 2.9 0.8 5.0 1.1 9.1 20.9 2.4 55.8 1.9 0.2 0.0 1.8 1.4 1.0 0.8 1.1 4.9 0.2 21.7 0.4 2.3 0.6 0.7 0.0 2.3 0.7 0.0 1.7 0.1 8.7 0.0 13.9 9.6 4.1 5.5 1.9 2.6 0.1 2.1 1.7 1.2 0.2 2.0 2.1 1.3 1.0 4.7 1.4 2.8 0.0 0.0 0.0 1.5 0.0 0.1 0.5 0.5 0.9 0.0 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.3 18.6 28.5 24.2 37.4 25.0 26.7 28.8 23.8 40.5 21.1 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 43.1;hTCEpi: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA069577: " "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.4 1.7 2.3 37.5 22.0 2.9 34.9 10.2 23.5 9.5 5.9 2.5 0.7 10.2 24.5 0.9 1.6 8.6 11.0 19.1 4.6 0.4 11.9 2.5 43.1 0.2 0.8 21.0 75.3 10.6 17.3 7.3 1.7 13.7 15.1 2.5 1.1 1.0 1.5 1.6 40.5 3.2 6.3 16.7 1.1 7.4 3.1 9.4 16.1 1.2 1.3 0.4 19.2 16.7 8.3 16.2 2.6 2.8 1.6 0.6 14.8 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell line enhanced" "Detected in many" "HaCaT: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favourable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.0 2.6 0.2 0.1 18.8 9.7 0.2 4.0 10.6 6.7 5.2 0.1 1.6 4.7 1.4 10.4 41.5 0.9 3.9 5.8 12.0 0.5 8.1 1.1 0.7 4.4 3.6 5.5 13.5 2.9 7.2 7.3 0.2 0.8 1.6 6.4 0.1 0.7 2.7 0.6 0.2 0.4 11.5 0.3 2.3 3.7 15.5 1.2 0.5 0.5 17.2 0.9 2.1 1.4 3.4 0.9 5.1 4.9 2.8 2.0 2.5 5.3 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: " "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavourable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 19.6 16.1 15.1 15.1 17.9 29.5 21.4 31.8 21.5 23.1 16.8 16.4 16.2 16.3 29.9 19.8 38.7 37.4 15.2 15.2 17.2 13.9 19.3 16.5 17.2 21.5 12.7 15.8 26.4 14.9 11.6 28.2 19.1 14.0 18.2 16.8 16.5 22.3 20.3 16.2 27.9 19.7 18.9 13.4 21.5 15.4 19.7 13.8 28.7 16.8 16.2 29.3 20.4 27.3 29.9 20.9 42.6 19.1 28.0 37.6 29.2 19.0 8.3 8.9 9.4 16.2 20.3 16.0 14.0 18.4 18.3 18.7 11.9 14.5 24.8 9.1 15.1 13.4 11.0 28.2 17.7 17.1 11.5 15.2 6.3 18.1 17.0 17.1 14.3 16.4 34.3 16.3 22.7 20.2 16.1 14.6 20.2 10.5 16.4 18.2 14.4 11.4 6.6 24.0 22.3 14.8 15.9 13.3 7.2 13.0 15.5 16.5 8.2 9.1 11.4 13.1 16.1 15.0 16.5 15.6 12.3 32.8 12.1 17.4 12.7 24.7 19.1 42.6 26.8 16.9 34.6 29.9 31.7 31.6 20.9 28.1 33.9 31.8 29.1 28.0 16.9 15.9 37.6 29.2 15.1 17.9 31.8 21.5 17.2 13.9 12.7 15.8 14.0 13.8 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavourable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.0 17.0 18.6 12.5 9.9 10.8 17.6 14.4 18.8 22.2 17.2 24.1 15.8 10.9 15.0 17.5 13.0 14.4 17.7 21.7 14.2 12.8 9.8 15.5 15.6 21.1 20.8 9.8 14.6 19.4 19.3 34.8 15.4 17.3 12.0 15.9 16.8 12.1 23.6 29.7 24.7 17.9 18.2 17.9 12.5 22.2 11.9 25.3 12.2 20.5 23.8 17.8 24.0 10.7 19.2 17.9 14.9 30.6 20.3 16.8 26.1 11.9 21.1 18.9 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 75.2;testis: 18.6;tongue: 26.0" "Cell line enhanced" "Detected in some" "BEWO: 4.9;EFO-21: 5.7;Hep G2: 11.9;K-562: 4.6;LHCN-M2: 10.6;RH-30: 9.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "neutrophil: 3.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 3.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "unprognostic (1.79e-1)" "unprognostic (2.39e-2)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.66e-3)" "unprognostic (2.47e-3)" "unprognostic (8.63e-2)" "unprognostic (1.97e-1)" "unprognostic (2.63e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-1)" "unprognostic (2.22e-7)" "unprognostic (1.93e-2)" "unprognostic (1.54e-1)" "unprognostic (4.81e-1)" "unprognostic (2.09e-2)" 0.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.2 0.0 0.0 5.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.3 0.0 75.2 0.1 0.0 0.0 0.0 0.1 0.0 18.6 0.0 0.0 1.0 26.0 1.9 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.1 0.1 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 11.9 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 4.6 0.0 10.6 0.6 0.0 0.0 0.7 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.7;BJ hTERT+ SV40 Large T+ RasG12V: 12.5;HBF TERT88: 17.9;WM-115: 10.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavourable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.0 6.1 10.7 12.5 0.9 1.8 0.1 0.7 5.8 1.3 0.1 4.7 17.9 0.1 0.5 0.0 1.0 2.0 0.8 0.4 1.2 4.7 2.9 3.8 2.0 0.2 0.4 0.0 7.9 0.3 0.8 0.2 0.2 0.0 0.7 0.5 0.2 2.6 0.7 1.3 0.1 0.4 0.7 1.1 0.6 1.0 0.7 8.6 2.0 0.1 4.0 0.0 0.2 0.1 0.0 0.0 10.3 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.3;REH: 17.4;SH-SY5Y: 5.0;SK-MEL-30: 4.3;U-2 OS: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA076649: " "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favourable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.3 0.1 1.0 2.2 0.3 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.7 0.7 0.0 17.4 2.0 0.1 0.0 0.0 2.4 5.0 2.8 0.0 4.3 1.3 1.0 0.0 0.0 4.2 0.0 0.0 1.8 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 24.2;RT4: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favourable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.1 5.2 2.7 1.8 2.4 8.7 1.7 3.7 4.1 6.0 12.2 5.3 0.2 0.9 1.8 1.8 9.2 1.5 5.9 8.9 4.6 0.4 4.4 13.6 3.9 0.8 1.9 1.9 4.6 3.3 10.9 3.2 2.4 7.5 0.3 6.0 1.0 0.6 24.2 1.3 1.2 1.7 5.0 2.6 22.0 7.9 7.6 6.6 8.9 4.4 3.4 1.5 2.8 1.9 5.5 1.2 1.9 5.3 6.1 0.9 2.5 1.8 2.6 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Nucleoplasm "CAB034070: AB_2094867, HPA051349: " "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.2 5.7 2.6 6.4 6.4 12.9 2.5 5.0 5.7 5.1 5.5 3.1 5.6 3.5 3.5 6.2 3.9 1.6 4.0 5.7 9.8 6.3 1.7 2.0 2.0 2.8 7.3 5.8 3.6 5.7 8.5 3.1 15.5 1.8 3.2 5.5 4.5 4.0 1.8 1.0 3.5 2.9 1.7 1.3 6.1 3.7 6.6 3.8 5.2 2.1 3.7 4.6 2.1 11.2 10.5 5.7 2.7 2.9 2.3 2.6 1.7 11.8 1.3 5.2 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.8 1.4 3.9 2.2 0.0 1.1 1.8 4.5 1.6 2.2 2.9 1.0 5.9 1.2 0.3 5.7 0.8 3.5 5.7 3.1 10.5 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.6 3.1 1.6 2.7 1.0 4.9 2.5 2.4 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 3.9 1.6 2.8 0.8 1.0 2.0 2.4 2.1 1.6 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;Karpas-707: 17.4;NB-4: 14.4;RT4: 17.3;SCLC-21H: 15.5;U-698: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" "Nuclear membrane" Nucleoplasm "HPA071920: " "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavourable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.2 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.5 2.1 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 17.4 0.1 2.6 12.4 14.4 3.4 5.4 0.0 0.2 12.1 0.1 17.3 15.5 0.8 0.7 0.2 2.8 1.0 7.2 0.0 0.0 4.1 0.0 0.8 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844004-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 15.9" "Group enriched" "Detected in some" 5 "CACO-2: 1.7;K-562: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 70.3;U-266/70: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.5 2.2 4.7 7.0 5.4 6.1 6.2 2.6 2.1 2.3 2.8 2.3 4.0 7.5 6.4 2.7 2.5 5.9 4.9 1.7 17.9 6.8 5.1 1.7 6.4 2.8 1.8 6.7 4.5 14.8 1.7 3.1 6.7 4.7 25.2 1.9 2.1 2.6 6.5 2.8 5.1 5.3 3.2 70.3 4.4 1.5 8.1 3.2 2.2 0.9 7.7 4.7 2.3 9.1 2.1 2.8 2.1 1.6 35.8 25.2 10.4 0.8 5.0 4.7 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell line enhanced" "Detected in many" "HSkMC: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm Nucleoplasm "HPA028211: , HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavourable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.0 0.1 5.0 4.1 5.9 4.6 5.3 14.0 0.0 29.9 5.4 0.5 3.4 4.5 3.2 3.0 1.5 16.8 4.7 0.0 19.2 10.1 12.9 46.6 12.2 3.8 13.8 22.4 7.6 6.1 8.2 22.1 1.0 0.4 22.7 18.8 0.0 0.0 5.7 7.1 2.1 5.7 12.7 9.0 19.9 23.2 12.8 15.9 16.4 4.9 0.2 0.6 0.0 4.3 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 45.1" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 45.1 10.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 DUSP27 ENSG00000198842 "Dual specificity phosphatase 27, atypical" Q5VZP5 1 167094045-167129165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "heart muscle: 46.8;skeletal muscle: 64.8;tongue: 18.2" "Cell line enriched" "Detected in some" 10 "RH-30: 17.7" "Group enriched" "Detected in many" 6 "colorectal cancer: 12.8;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA012912 Approved Nucleoplasm Nucleoplasm "HPA012912: " "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.44e-3)" "unprognostic (1.22e-1)" "unprognostic (2.10e-3)" "unprognostic (4.65e-2)" "unprognostic (1.53e-1)" "unprognostic (8.19e-2)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.72e-1)" "unprognostic (7.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 2.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.1 46.8 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.0 0.9 0.0 64.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 18.2 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favourable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.5 1.4 0.7 2.3 1.9 1.1 1.5 1.1 0.9 4.4 2.7 1.0 1.2 4.9 1.7 0.6 1.6 3.3 6.2 3.8 3.3 2.4 1.0 2.5 6.6 1.6 1.7 1.0 1.3 0.7 2.7 3.2 1.3 1.8 3.1 4.0 1.4 1.4 3.8 4.7 3.6 1.1 2.9 4.8 2.7 1.8 1.9 2.1 2.3 4.3 1.7 3.5 2.8 2.2 1.7 12.9 3.7 4.3 2.1 1.9 2.7 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol 1300000 Nucleoplasm Cytosol "HPA063616: " "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favourable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.9 19.8 7.6 8.1 22.3 12.0 6.5 8.3 19.9 19.4 23.5 19.0 7.4 1.7 13.2 15.5 9.5 11.8 10.2 20.5 3.7 9.0 5.5 9.1 15.5 27.3 0.6 5.7 11.1 18.4 14.9 13.1 13.5 4.9 1.9 22.6 7.8 2.8 2.8 3.5 14.5 3.6 23.0 4.1 26.9 11.5 4.3 7.7 9.7 6.5 24.4 29.1 15.4 14.0 22.0 14.9 31.2 13.7 10.2 13.4 0.4 26.1 7.7 7.3 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell line enhanced" "Detected in many" "A549: 30.0;SK-MEL-30: 46.2;WM-115: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm Nucleoplasm "HPA061967: " "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavourable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 30.0 17.8 0.8 2.3 0.0 1.5 2.3 12.8 7.0 3.1 0.3 5.7 0.0 6.3 1.0 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.2 13.1 5.7 0.1 1.3 14.0 12.6 0.0 2.1 3.1 18.4 0.3 0.6 2.3 16.1 5.9 0.1 9.9 3.2 15.2 46.2 3.2 0.3 16.0 5.2 0.0 0.0 1.6 3.6 0.4 0.0 15.6 2.6 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497838-110511544 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 85.9;Karpas-707: 33.3;U-266/70: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.4;non-classical monocyte: 8.8;plasmacytoid DC: 13.3" "Group enriched" "Detected in many" 19 "dendritic cells: 13.3;monocytes: 8.8;T-cells: 3.4" "Region enhanced" "Detected in many" "cerebellum: 68.0" "Region enriched" "Detected in many" 5 "cerebellum: 41.9" "unprognostic (1.25e-1)" "unprognostic (3.57e-1)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" "unprognostic (6.35e-2)" "prognostic unfavourable (8.30e-6)" "unprognostic (1.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.91e-2)" "unprognostic (1.20e-2)" "unprognostic (4.20e-3)" "unprognostic (3.79e-1)" "unprognostic (3.78e-3)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" 13.7 11.0 2.8 12.4 5.1 14.5 11.2 19.8 5.2 15.1 12.5 3.3 7.7 5.4 9.1 8.8 55.5 5.6 24.2 11.3 5.2 3.3 9.1 13.1 12.1 9.3 2.9 2.8 6.5 3.9 5.5 8.0 45.1 5.6 15.6 12.4 21.0 9.4 10.0 1.8 6.5 17.6 10.3 7.1 11.4 10.2 13.1 2.1 4.8 7.8 21.9 47.8 31.6 14.3 0.2 13.3 0.4 8.8 0.0 3.4 0.5 4.3 2.9 0.6 1.5 2.3 9.9 2.2 10.3 23.5 5.6 6.7 1.8 5.9 0.5 1.9 2.5 1.4 0.5 5.4 9.1 12.4 0.3 2.4 0.5 1.1 8.9 0.6 3.1 3.8 7.4 17.8 85.9 3.5 0.4 33.3 16.7 1.1 0.1 1.8 1.9 4.5 0.0 1.3 7.6 19.1 8.5 0.3 0.8 0.6 1.6 3.4 0.9 0.7 5.3 1.9 1.3 4.5 4.9 47.5 8.4 1.2 7.3 3.3 1.3 0.4 0.2 0.0 3.4 2.0 1.2 0.2 1.8 1.0 0.9 0.0 0.0 1.1 0.1 0.0 8.8 13.3 0.0 0.5 2.8 5.1 19.8 5.2 5.2 3.3 2.9 2.8 5.6 2.1 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell line enhanced" "Detected in many" "AN3-CA: 80.6;NB-4: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favourable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.0 80.6 20.8 17.7 0.0 8.7 11.1 1.7 1.3 7.0 1.2 0.0 2.0 3.7 9.3 0.1 21.6 2.5 0.1 0.1 3.6 0.2 11.2 14.7 15.5 39.5 3.4 7.6 15.3 14.3 40.1 0.0 3.8 5.5 0.5 0.5 57.8 14.6 19.7 39.3 3.0 1.5 24.8 23.3 0.4 17.1 0.2 0.1 45.9 1.2 8.6 10.7 5.9 0.1 1.1 4.1 0.6 3.1 0.0 24.5 10.9 37.4 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 40.7;hTERT-HME1: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavourable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.4 1.6 1.9 4.3 6.2 5.4 2.3 7.6 14.5 7.6 5.5 2.0 3.8 2.0 2.1 11.2 8.9 7.2 27.5 5.2 1.7 2.9 9.9 3.8 3.6 5.0 8.8 6.0 5.6 40.7 9.8 34.6 7.2 5.6 6.0 6.0 2.0 6.5 12.4 4.7 13.7 5.5 1.6 5.5 3.1 3.2 2.4 7.0 3.4 3.1 5.3 1.1 21.2 9.4 14.6 9.4 15.3 23.1 2.9 2.7 3.4 8.1 14.9 4.6 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell line enhanced" "Detected in some" "MCF7: 6.1;SH-SY5Y: 5.4;U-251 MG: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favourable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.1 0.4 1.2 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 1.8 0.0 6.1 0.0 0.4 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.4 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Cell line enriched" "Detected in some" 9 "Hep G2: 88.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 8.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.5 0.5 0.0 3.9 0.0 1.8 9.8 0.2 0.0 0.2 1.8 0.0 0.7 88.7 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.1 0.2 3.6 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.5 0.7 0.3 0.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.2 8.0 16.3 11.5 7.8 8.5 14.5 9.1 11.7 9.3 9.8 11.4 9.0 13.8 6.2 16.0 7.0 11.9 8.9 10.9 21.1 5.1 40.8 13.3 6.9 11.7 16.1 15.0 8.6 10.6 12.0 18.5 9.6 15.4 32.0 9.6 10.3 21.1 11.0 17.3 4.8 27.4 9.0 12.7 9.7 13.4 16.9 9.4 20.8 14.3 14.3 13.4 15.0 12.3 12.7 3.8 7.9 7.6 21.8 16.9 19.8 10.1 18.2 13.8 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Cell line enhanced" "Detected in many" "SCLC-21H: 12.1;SH-SY5Y: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported Nucleoplasm Nucleoplasm "HPA028522: , HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favourable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.3 5.9 4.7 4.5 0.7 2.7 1.7 2.5 2.2 0.8 3.3 1.3 10.6 3.2 2.9 1.2 1.9 2.2 4.9 7.2 0.6 5.3 0.8 4.0 0.3 1.8 6.0 1.2 0.8 2.8 0.6 1.3 1.9 0.4 4.2 1.9 0.7 2.0 1.9 0.9 0.1 0.6 5.4 2.1 12.1 13.7 4.2 4.2 0.2 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: " "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.5 7.7 11.5 8.3 5.8 7.9 9.2 13.8 9.0 6.8 3.9 10.1 7.5 25.4 17.1 20.0 15.9 9.2 5.4 7.3 10.9 12.0 4.1 5.1 3.8 2.2 9.2 8.9 6.5 7.8 18.2 14.6 3.8 5.0 13.3 8.6 7.8 7.9 4.5 10.0 12.4 21.1 11.4 11.2 7.9 17.1 15.2 18.0 5.8 7.8 8.0 5.3 7.8 5.6 10.8 10.2 7.4 10.9 6.3 1.0 14.1 10.4 6.3 11.1 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA075041 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA075041: " "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavourable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.4 0.8 4.8 8.6 7.7 0.1 8.1 17.9 7.4 9.6 0.2 1.2 3.7 1.2 9.5 0.7 4.2 6.5 7.9 0.0 2.8 5.4 4.4 0.8 13.7 3.7 3.5 5.4 4.2 12.8 35.2 5.7 10.3 0.7 11.4 0.9 8.1 2.1 6.8 6.4 20.2 2.6 0.0 2.3 0.1 4.9 3.6 7.3 0.3 9.9 0.9 0.9 4.3 15.5 5.9 7.5 6.7 2.9 1.0 4.4 9.2 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Cell line enhanced" "Detected in many" "HHSteC: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028065, HPA056073" Enhanced Enhanced Vesicles Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.9 4.2 5.9 7.2 4.6 2.3 4.7 5.3 5.8 0.6 3.1 5.8 0.3 6.6 4.0 2.9 4.3 4.2 4.4 6.6 4.0 0.8 3.3 16.6 3.5 3.2 4.9 9.3 3.7 12.3 7.5 1.6 6.6 4.8 4.0 3.2 8.6 5.2 1.8 0.7 2.8 2.5 6.5 1.9 0.0 1.5 0.4 2.3 3.3 1.8 3.1 0.5 6.3 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell line enriched" "Detected in many" 12 "A-431: 337.7" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: , CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavourable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 337.7 4.3 1.1 1.5 6.9 4.3 1.1 3.3 4.5 2.0 1.6 0.8 3.7 0.2 0.8 2.8 13.5 0.0 14.9 2.5 0.1 0.2 0.0 1.8 0.2 1.8 0.0 0.0 2.1 13.7 5.2 27.9 0.2 0.0 0.0 4.4 0.2 0.0 0.0 0.3 2.2 0.0 0.6 0.0 2.5 3.6 0.0 1.3 2.8 3.4 0.6 0.3 0.7 1.0 1.9 0.5 14.6 3.1 0.0 0.3 0.1 2.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408892 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 104.4" "Cell line enhanced" "Detected in some" "CACO-2: 10.3;HaCaT: 9.6;HBEC3-KT: 7.8;MCF7: 8.5;NTERA-2: 32.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 3.4;naive CD4 T-cell: 6.9;naive CD8 T-cell: 5.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.9" "Not detected" "Not detected" CAB026144 Uncertain 24000000 "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favourable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.4 0.4 0.0 2.0 0.1 0.5 1.2 0.9 0.3 5.7 7.9 0.0 3.3 3.3 0.9 1.4 29.3 1.6 7.9 0.4 0.0 0.0 2.8 10.6 2.9 5.8 0.0 0.0 1.2 2.9 104.4 1.3 5.5 1.1 2.1 0.9 1.3 5.8 3.9 0.3 9.5 12.3 0.4 0.2 0.5 1.8 0.8 0.0 5.1 6.0 16.4 17.2 1.6 11.8 0.0 0.7 0.2 0.1 0.2 6.9 1.6 4.9 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 10.3 4.1 0.0 0.0 0.0 9.6 0.0 7.8 0.0 0.0 0.0 1.0 0.0 0.9 0.0 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 1.0 32.1 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.0 0.0 4.8 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 3.4 0.9 0.4 0.0 6.9 5.1 0.2 0.2 0.0 0.7 0.2 1.6 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 1.1 0.0 EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.6;intestine: 12.6;testis: 24.8" "Cell line enhanced" "Detected in some" "BEWO: 5.1;HDLM-2: 19.2;SCLC-21H: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" HPA027497 Uncertain "Intracellular and membrane" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 0.4 1.1 5.8 1.7 15.6 0.7 1.9 1.3 10.5 0.6 12.6 3.6 0.2 5.8 0.5 6.8 0.8 1.8 2.1 0.4 4.6 7.4 0.5 0.4 0.5 0.6 3.5 5.0 0.4 5.1 1.1 10.8 0.4 6.4 1.4 10.3 1.6 2.4 0.7 0.4 0.6 7.3 1.0 2.3 0.5 5.3 24.8 2.1 0.0 1.0 0.0 0.5 0.6 0.3 0.4 0.3 1.5 0.3 0.8 0.7 0.1 1.5 1.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.6 2.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 19.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.0 0.2 0.7 0.6 0.0 0.0 0.4 0.3 1.7 8.9 0.4 1.1 0.0 0.0 2.8 0.1 0.0 0.0 1.0 0.1 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.4 0.2 0.1 0.7 0.1 0.4 0.4 0.3 0.3 0.1 0.4 0.6 0.7 1.5 0.8 0.3 0.3 0.2 0.1 5.8 15.6 1.3 10.5 4.6 7.4 3.5 5.0 6.4 2.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156087 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 41.9;EFO-21: 40.4;PC-3: 48.0;U-251 MG: 49.2;WM-115: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 115 "plasmacytoid DC: 11.4" "Lineage enriched" "Detected in single" 115 "dendritic cells: 11.4" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 6.7 3.4 1.3 3.1 2.6 0.0 5.2 0.5 2.1 12.1 4.9 1.6 1.9 4.3 7.8 3.8 51.2 4.6 16.7 6.4 1.1 0.8 5.7 8.2 6.6 4.7 2.7 1.3 4.5 10.2 2.2 2.8 8.9 3.4 5.8 2.6 5.4 31.0 2.8 3.4 12.7 13.1 2.7 3.0 2.8 6.8 2.4 1.2 1.2 5.7 21.8 25.5 15.2 18.5 0.0 11.4 0.0 0.0 0.0 0.0 0.0 15.4 31.3 8.7 4.2 0.6 0.7 5.1 9.3 13.3 17.0 10.8 13.0 41.9 0.0 40.4 5.3 6.3 2.0 21.6 5.9 0.0 1.4 0.0 9.1 8.3 11.1 0.0 0.0 1.0 8.1 9.2 20.5 18.1 0.0 0.0 10.7 4.9 0.0 0.0 4.2 48.0 0.0 7.9 0.0 18.0 8.0 0.0 1.3 18.2 4.4 1.2 0.6 0.1 22.3 6.1 16.3 0.4 49.2 0.0 0.1 0.1 4.7 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 1.3 2.6 0.5 2.1 1.1 0.8 2.7 1.3 3.4 1.2 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107524-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.0" "Cell line enriched" "Detected in some" 6 "AF22: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 9.7 1.1 2.3 1.7 4.5 0.2 5.1 1.3 8.7 12.3 5.8 0.6 1.4 2.2 13.9 1.3 6.3 2.6 17.2 10.0 2.2 2.5 1.5 4.4 2.7 3.0 2.5 3.4 4.2 2.8 1.2 3.4 17.5 11.9 39.0 5.9 5.4 3.8 6.8 1.7 1.7 3.5 17.3 2.9 1.2 3.7 1.3 2.0 0.0 16.3 6.0 3.0 11.8 12.2 0.3 0.1 0.5 0.1 0.3 0.2 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 3.7 0.0 0.2 0.0 0.8 0.0 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.3 0.1 0.1 0.0 0.0 2.3 4.5 1.3 8.7 2.2 2.5 2.5 3.4 11.9 2.0 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6" "Cell line enhanced" "Detected in many" "AF22: 35.0;ASC diff: 15.5;CACO-2: 25.6;U-2197: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 3.0;gdT-cell: 3.4;MAIT T-cell: 3.4;memory B-cell: 2.5;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.3;naive B-cell: 1.8;naive CD4 T-cell: 1.9;NK-cell: 6.0;T-reg: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB028368 Enhanced 8400000 "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favourable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.1 1.8 8.1 1.9 18.3 3.5 5.2 14.7 29.6 4.9 5.9 3.1 3.2 1.1 6.5 3.1 5.0 6.6 3.3 16.7 19.9 4.4 5.2 0.9 3.7 2.5 2.4 16.4 11.7 1.2 2.0 1.2 1.7 4.9 5.9 4.7 0.8 3.7 6.7 3.1 12.8 4.1 8.2 2.1 3.3 4.0 11.4 2.6 0.5 9.8 3.7 3.2 4.6 4.9 2.5 0.2 3.0 0.0 6.0 5.0 0.7 1.1 1.0 35.0 0.0 15.5 9.6 0.0 8.3 3.6 7.5 2.8 25.6 0.4 0.0 0.0 11.6 3.0 5.4 0.0 3.2 4.1 3.0 0.0 0.3 0.0 0.4 0.0 0.6 3.8 1.9 2.3 0.0 7.1 0.0 0.0 1.9 4.1 0.1 0.0 2.5 0.7 0.0 3.8 0.0 11.7 1.8 6.2 0.0 2.7 0.5 0.6 1.3 0.0 0.0 0.8 1.4 17.1 0.4 0.0 0.0 0.0 3.1 0.0 1.5 3.0 0.0 0.0 3.4 0.0 3.4 2.5 5.0 3.3 0.0 1.8 1.9 0.3 0.2 6.0 0.0 0.2 2.1 0.7 8.1 18.3 14.7 29.6 19.9 4.4 2.4 16.4 4.9 2.6 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.5" "Cell line enhanced" "Detected in some" "PC-3: 7.0;TIME: 9.4;U-138 MG: 19.7;U-2197: 12.0;U-251 MG: 15.2" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.9 2.7 17.6 1.0 9.0 0.8 0.8 1.9 25.5 5.9 1.2 1.5 1.8 0.9 1.9 0.9 1.1 1.0 0.9 2.7 17.3 6.8 0.9 0.8 1.1 0.9 5.4 13.2 6.2 0.8 0.8 6.5 2.7 10.2 4.2 1.1 2.6 1.2 4.1 0.8 1.2 0.9 1.4 17.7 1.5 1.1 2.2 0.7 0.0 3.0 0.0 0.8 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.3 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.1 1.9 0.0 0.0 0.0 0.0 7.0 0.0 2.2 0.4 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.0 0.0 9.4 19.7 2.5 12.0 15.2 0.0 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.0 1.9 24.7 17.3 6.8 5.4 13.2 10.2 0.7 EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97752460 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;ovary: 13.2;testis: 15.5" "Group enriched" "Detected in some" 6 "HEK 293: 8.0;U-266/70: 24.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA007397: AB_2667821, HPA058047: " "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" 0.8 0.5 8.7 0.5 9.8 0.3 0.8 27.9 9.9 2.2 5.8 1.1 0.3 0.6 2.2 1.0 2.1 4.2 2.1 1.1 15.4 1.3 1.3 0.5 0.5 0.4 1.1 6.8 13.2 1.4 0.7 0.6 0.5 5.7 2.5 1.8 0.2 0.6 1.7 0.4 0.5 1.1 3.2 0.8 0.4 1.7 15.5 2.8 0.0 4.3 0.0 0.5 2.1 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 8.0 0.0 2.0 0.0 0.0 1.9 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.0 2.1 0.0 0.8 24.3 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 9.8 27.9 9.9 15.4 1.3 1.1 6.8 5.7 2.8 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419547 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 110.4" "Group enriched" "Detected in some" 4 "AF22: 8.7;HEK 293: 25.0;RH-30: 23.8;THP-1: 20.3" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" 340000 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 1.3 1.3 6.0 1.7 24.6 1.2 2.2 21.6 8.6 2.4 24.6 0.0 0.1 2.5 2.0 7.5 14.7 1.7 3.1 4.2 13.8 2.9 6.9 1.3 1.5 1.3 2.4 5.8 3.0 1.3 110.4 5.6 1.6 6.7 17.9 3.6 0.4 8.2 1.9 1.3 1.4 6.5 20.2 4.8 4.7 14.9 2.1 4.4 0.0 1.3 0.0 1.3 9.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.5 0.6 4.4 23.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 24.6 21.6 8.6 13.8 2.9 2.4 5.8 6.7 4.4 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563564-22603594 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 9.4;brain: 5.3;lymphoid tissue: 10.3;pancreas: 8.3;testis: 3.5" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 36.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 25.0" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.2 9.4 1.6 0.2 3.1 0.2 0.1 1.8 3.9 0.2 0.2 2.2 0.0 1.7 0.1 0.3 0.2 0.1 0.2 0.2 2.0 2.6 0.1 0.1 0.2 0.2 2.1 4.1 0.1 8.3 0.2 1.7 0.1 5.3 0.2 0.2 1.6 0.8 0.2 0.3 0.4 0.2 0.1 1.3 10.3 0.2 3.5 0.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 36.4 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.8 3.9 2.0 2.6 2.1 4.1 5.3 0.6 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 74.7" "Group enriched" "Detected in some" 4 "HDLM-2: 33.9;HMC-1: 20.1;RPTEC TERT1: 9.2" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Region enhanced" "Detected in all" "cerebellum: 74.7" "Group enriched" "Detected in some" 33 "neutrophil: 15.9;plasmacytoid DC: 15.4" "Group enriched" "Detected in many" 33 "dendritic cells: 15.4;granulocytes: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: " "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 2.0 1.5 9.0 1.8 16.6 1.5 5.5 74.7 23.6 3.6 3.4 3.4 3.1 2.8 4.1 2.0 3.8 2.8 3.3 1.1 9.4 5.3 2.3 2.9 1.0 3.3 2.8 7.0 1.7 1.1 0.6 3.8 0.9 7.1 3.3 1.4 1.9 3.9 5.1 7.4 6.0 1.7 1.7 6.0 3.4 1.3 16.7 6.0 0.0 11.6 2.9 3.3 4.5 2.6 0.0 15.4 15.9 0.0 0.0 0.4 0.1 0.0 0.0 4.7 0.0 0.1 0.0 0.1 3.5 0.0 0.2 0.0 0.0 0.0 0.6 1.0 1.8 0.0 3.1 0.0 0.6 33.9 0.4 2.5 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 0.1 0.1 0.1 1.3 0.0 0.0 0.5 0.1 9.2 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.6 2.0 0.3 4.2 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 15.4 0.0 0.1 9.0 16.6 74.7 19.0 9.4 5.3 2.8 7.0 7.1 6.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 22.8;HUVEC TERT2: 31.1;TIME: 30.7;U-251 MG: 26.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.5;intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" 290000 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: " "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favourable (4.98e-4)" "prognostic unfavourable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.7 2.9 3.4 15.4 5.4 0.9 2.5 1.9 8.2 3.8 23.9 16.2 4.6 21.6 2.5 3.2 1.1 5.4 4.4 5.4 5.6 6.5 3.5 1.1 3.0 5.5 12.7 3.8 17.9 5.4 6.1 5.4 12.0 8.2 3.3 25.0 2.2 6.6 4.0 0.7 1.8 22.6 4.0 12.1 3.3 2.3 2.9 9.3 0.1 8.4 1.0 2.1 5.3 3.3 0.1 0.6 0.3 2.5 0.1 0.1 0.4 16.7 7.1 6.8 10.9 0.6 0.6 0.0 3.9 0.2 11.8 2.5 2.4 6.7 0.2 8.4 1.7 15.8 4.6 22.8 3.1 0.0 1.6 0.0 0.7 0.0 7.1 0.0 1.7 2.3 7.3 21.1 0.1 31.1 0.6 0.0 2.3 2.5 0.3 0.1 1.6 4.6 2.0 7.0 0.3 5.8 1.6 7.4 7.8 6.8 0.2 0.1 0.4 0.2 30.7 4.7 12.4 11.9 26.8 0.0 0.1 0.0 8.8 0.3 0.1 0.3 2.5 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 3.4 5.4 1.9 8.2 5.6 6.5 12.7 3.8 8.2 9.3 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561784-184582409 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 49.3" "Cell line enhanced" "Detected in many" "BEWO: 17.2;HaCaT: 23.6;SK-BR-3: 18.3;T-47d: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.1;myeloid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;monocytes: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced 20000 "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavourable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.4 0.9 4.5 5.0 2.6 0.5 9.0 9.7 5.7 22.7 8.8 2.3 1.7 5.7 10.0 1.9 19.9 3.0 9.7 1.6 4.7 1.8 1.7 1.0 4.7 1.0 3.3 3.7 9.0 49.3 1.1 1.7 6.3 7.2 7.7 9.7 3.8 27.7 3.5 0.7 32.3 5.6 3.5 1.3 1.2 16.0 1.1 4.0 0.2 1.0 15.7 8.4 4.0 13.6 0.0 3.1 0.3 1.1 0.0 0.4 0.4 3.8 1.3 8.9 0.9 2.7 0.2 17.2 0.6 1.1 1.3 0.7 1.2 0.1 0.0 1.7 3.6 23.6 3.2 1.2 0.3 0.1 0.7 0.0 0.2 0.0 0.2 0.0 0.2 0.7 7.7 1.1 0.1 0.0 0.0 0.0 0.6 10.1 0.0 3.8 0.9 1.5 0.9 5.4 0.0 0.0 3.4 1.1 1.3 0.7 18.3 0.8 12.1 0.1 0.0 2.2 3.2 1.1 1.4 0.0 0.0 0.1 0.2 0.0 8.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.1 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.4 4.5 2.6 9.7 5.7 4.7 1.8 3.3 3.7 7.2 4.0 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827521 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 3.6;neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain 1000000 "CAB013537: " "prognostic unfavourable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavourable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavourable (8.84e-4)" 14.0 20.7 1.8 4.2 2.9 2.2 17.1 1.9 3.0 29.1 9.5 2.9 14.6 4.1 28.8 10.3 11.0 13.1 35.0 19.0 3.4 1.1 16.8 29.8 16.5 12.0 2.2 0.9 24.6 11.6 5.6 3.1 35.5 3.2 13.7 5.4 11.6 10.8 14.7 5.1 14.2 7.0 12.4 2.2 50.5 8.6 12.2 2.1 2.3 10.2 13.1 7.0 7.7 21.5 0.0 1.6 7.4 3.6 0.0 0.0 1.2 12.5 11.1 11.1 32.2 7.1 4.6 32.9 4.9 10.7 7.7 10.1 9.1 9.6 1.6 22.4 5.0 13.1 4.8 12.9 4.1 2.0 8.9 0.4 6.4 14.1 4.1 0.2 0.3 5.4 19.5 4.9 11.4 28.7 23.6 0.6 6.2 21.8 0.2 4.9 19.0 16.7 17.0 5.5 2.9 9.8 6.6 0.0 9.6 7.5 3.5 7.3 8.9 2.2 24.1 9.6 15.3 17.7 7.2 0.1 0.2 0.5 1.4 4.1 17.4 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 7.4 0.0 0.2 0.3 0.0 1.2 1.8 2.9 1.9 3.0 3.4 1.1 2.2 0.9 3.2 2.1 EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 30.1;lymphoid tissue: 26.7;skin 1: 32.1" "Group enriched" "Detected in some" 6 "MOLT-4: 17.8;RT4: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035784 Approved "Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" "HPA035784: " "unprognostic (1.90e-2)" "prognostic favourable (1.80e-4)" "unprognostic (7.08e-3)" "unprognostic (2.95e-2)" "prognostic unfavourable (4.10e-4)" "unprognostic (2.53e-3)" "unprognostic (3.15e-2)" "unprognostic (4.39e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.06e-3)" "unprognostic (3.18e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.16e-1)" "prognostic favourable (4.68e-5)" 3.3 1.7 7.4 3.0 30.1 3.3 2.6 3.1 29.3 9.0 1.5 0.8 3.4 0.9 3.0 4.5 7.5 6.4 2.8 1.4 5.4 4.2 1.7 1.3 2.4 3.6 3.3 14.4 3.9 7.8 0.8 1.1 2.9 1.7 6.8 0.9 1.5 4.7 8.1 1.8 32.1 1.6 2.0 1.4 2.6 3.3 3.8 3.6 26.7 6.6 2.5 3.3 5.1 6.5 4.1 0.9 1.0 1.3 0.0 3.1 1.4 0.1 0.0 0.0 0.4 1.9 1.0 0.0 0.2 0.4 0.1 0.0 0.5 1.3 0.0 0.0 0.1 4.4 0.2 0.0 0.0 1.0 0.1 0.3 0.0 0.2 0.6 4.2 0.1 0.3 0.0 1.1 0.0 0.2 0.6 0.0 0.0 0.0 17.8 3.2 3.0 1.3 0.4 0.0 0.0 0.0 33.8 0.0 0.0 1.2 0.8 0.0 2.8 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 1.3 0.5 0.1 1.0 0.6 4.1 2.5 1.4 0.9 1.0 3.1 1.5 1.0 0.0 0.4 0.1 1.9 1.4 7.4 30.1 3.1 29.3 5.4 4.2 3.3 14.4 1.7 3.6 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm Nucleoplasm "HPA053643: , HPA055468: " "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favourable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.2 6.2 8.0 2.5 1.4 2.9 3.4 2.7 3.4 1.5 1.6 19.9 2.5 3.5 1.7 1.2 1.2 2.5 7.7 1.6 3.2 2.3 2.5 4.9 11.0 2.0 2.0 6.6 1.6 0.5 1.9 1.4 5.1 3.4 2.6 7.3 2.4 3.3 1.7 4.2 2.9 5.8 2.4 1.6 6.0 5.9 5.2 3.1 6.8 1.8 6.4 4.2 2.8 1.3 2.6 2.3 3.7 3.7 8.0 2.4 2.7 4.3 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in many" 27 "SK-BR-3: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.8" "Lineage enriched" "Detected in many" 4 "T-cells: 8.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Plasma membrane,Cytosol" 430000 "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: , HPA001060: , HPA001338: , HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavourable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favourable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 5.8 2.4 5.2 10.4 7.0 0.1 20.1 4.2 7.0 19.1 46.5 9.1 55.2 21.6 14.9 18.7 40.9 22.7 26.6 24.8 6.3 3.1 37.5 21.5 17.6 3.7 5.1 5.6 19.3 16.2 27.7 8.1 60.8 7.5 23.6 16.6 15.9 28.7 58.1 8.9 35.3 47.2 10.9 4.5 4.0 17.1 6.5 3.7 2.8 35.7 20.8 22.9 19.7 20.3 1.3 0.3 2.1 0.4 0.9 8.8 2.2 3.1 3.8 4.2 2.7 5.1 3.6 5.7 2.2 3.7 4.9 4.2 2.8 8.6 0.2 4.6 5.1 9.8 0.2 5.1 2.3 0.4 3.2 0.1 3.0 4.5 3.0 0.0 0.0 3.5 4.8 3.0 1.8 2.0 0.4 0.1 3.6 4.8 0.5 0.2 7.6 0.9 0.3 1.7 0.4 5.0 9.8 0.8 0.2 4.2 263.9 1.3 7.4 0.1 0.2 2.5 3.3 3.2 1.4 0.4 0.2 0.2 0.2 0.0 8.2 1.6 0.4 0.8 8.8 0.3 0.7 0.9 0.5 2.5 0.3 1.3 1.0 2.5 2.1 0.9 0.2 0.2 0.4 2.2 5.2 7.0 4.2 7.0 6.3 3.1 5.1 5.6 7.5 3.7 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 31.1;MCF7: 20.3;RT4: 24.3;SK-BR-3: 28.6;SK-MEL-30: 38.1;T-47d: 31.7;WM-115: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.3" "Low region specificity" "Detected in many" "CAB025331, HPA045396" Uncertain Approved "Plasma membrane,Actin filaments" "Secreted - unknown location" 420000 "Actin filaments" "Plasma membrane" "CAB025331: , HPA045396: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 1.1 1.4 11.6 12.6 16.5 0.6 26.8 2.0 16.7 6.8 40.5 40.3 12.0 37.7 2.8 7.5 29.4 5.7 22.9 3.4 18.6 9.0 16.5 33.9 13.4 0.5 23.5 9.3 0.9 21.5 11.4 1.0 15.4 14.9 16.8 29.7 5.5 36.8 22.3 1.1 30.7 41.3 3.2 27.4 0.5 32.9 1.2 23.8 0.0 4.5 7.4 8.5 11.8 14.4 0.9 0.7 5.3 0.6 1.2 1.2 0.2 10.1 0.6 0.8 0.3 0.0 0.0 16.5 0.8 1.9 1.1 1.1 5.5 18.3 0.0 0.2 0.2 8.6 1.2 1.9 0.6 0.2 0.8 0.0 0.3 31.1 0.0 0.0 0.1 0.4 2.5 0.2 0.0 0.0 0.7 0.3 0.1 20.3 0.1 0.3 2.8 0.4 0.1 1.9 0.5 2.1 24.3 0.9 0.3 0.7 28.6 38.1 31.7 0.1 0.0 0.1 1.1 0.6 0.1 0.3 0.1 0.1 0.1 0.0 40.5 5.3 0.4 0.8 0.9 0.4 0.4 0.4 0.7 0.3 0.3 0.9 0.6 1.2 3.3 1.2 0.6 0.7 0.8 0.2 11.6 16.5 2.0 16.7 18.6 9.0 23.5 9.3 14.9 23.8 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.5" "Cell line enhanced" "Detected in some" "AF22: 9.4;EFO-21: 7.0;HEK 293: 5.2;RPTEC TERT1: 7.7;SCLC-21H: 4.3;T-47d: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 4.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced 140000 "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 1.6 1.9 15.1 1.2 15.0 1.0 13.4 18.6 14.1 7.8 1.1 7.6 8.8 1.1 1.5 1.2 1.3 24.5 1.2 7.0 14.3 6.5 11.9 1.1 2.9 1.2 7.8 10.7 1.3 2.4 10.8 5.1 1.3 8.8 1.7 1.1 2.0 9.7 18.1 3.8 1.8 1.2 1.1 7.3 1.2 1.5 7.6 12.0 0.0 4.5 1.1 1.2 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.4 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 7.0 1.0 0.4 0.2 0.0 0.0 0.1 5.2 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.7 0.4 4.3 0.2 0.0 0.1 0.1 6.9 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 18.6 14.1 14.3 6.5 7.8 10.7 8.8 12.0 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.5;pituitary gland: 30.8" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;RH-30: 12.7;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "NK-cell: 9.8" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028917 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA028917: " "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 1.0 1.1 2.8 0.6 16.8 0.5 0.6 0.2 6.8 4.0 0.6 1.9 0.0 0.7 0.6 2.2 1.0 2.5 0.8 4.6 2.8 2.2 0.6 0.5 1.0 0.6 2.9 2.8 0.8 0.6 45.5 30.8 0.6 4.2 12.4 0.7 15.3 1.2 4.6 3.2 0.6 0.7 3.9 0.4 0.7 0.9 1.3 5.1 4.4 0.9 2.9 0.6 3.5 5.7 0.8 1.9 1.8 2.3 9.8 2.3 0.2 0.1 0.0 3.7 16.4 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.9 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.2 0.9 0.0 12.7 5.4 0.0 0.0 1.3 31.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.2 1.8 0.3 0.6 0.9 0.9 1.9 0.8 0.7 1.9 0.7 0.8 1.3 1.4 1.6 9.8 2.3 1.9 2.3 0.2 2.8 16.8 0.2 2.8 2.8 2.2 2.9 2.8 4.2 5.1 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 47.4" "Cell line enhanced" "Detected in some" "HBEC3-KT: 13.4;SCLC-21H: 20.4;U-266/70: 38.0;U-266/84: 46.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16 "memory B-cell: 2.4" "Lineage enriched" "Detected in single" 16 "B-cells: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol Cytosol "HPA027024: AB_1848334, HPA059291: " "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 10.5 2.0 6.5 2.6 7.4 0.8 13.4 2.4 6.5 47.4 6.4 3.8 21.0 1.0 15.7 10.7 25.9 28.2 2.2 4.3 7.0 4.1 5.2 1.8 2.3 1.3 6.3 4.9 5.2 2.4 11.5 4.7 5.9 9.1 18.5 3.2 15.4 28.6 27.3 2.1 4.2 1.1 2.3 7.2 1.1 8.2 4.9 5.1 14.3 21.4 3.6 14.0 5.5 17.3 2.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.1 13.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 20.4 0.0 0.0 9.1 0.0 1.8 0.0 0.0 0.0 1.6 0.1 3.0 38.0 46.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 7.4 2.4 6.5 7.0 4.1 6.3 4.9 9.1 5.1 EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088696 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA052432: , HPA062889: " "unprognostic (3.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (8.74e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.11e-4)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (4.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (8.98e-2)" "prognostic favourable (3.15e-6)" "unprognostic (5.17e-2)" "unprognostic (2.79e-1)" "unprognostic (7.60e-2)" "unprognostic (6.11e-2)" 12.8 10.0 14.9 24.0 12.9 8.6 13.3 21.9 13.8 14.7 10.2 14.4 12.8 10.7 14.4 12.4 19.4 11.8 8.1 11.7 10.6 11.8 21.6 11.3 12.5 15.6 11.1 8.8 12.4 12.9 20.9 29.2 13.8 12.9 11.8 11.7 16.4 11.8 13.1 14.5 16.3 12.2 10.5 10.1 14.2 10.0 20.6 13.7 17.4 17.3 12.2 25.0 10.7 13.8 8.6 12.4 10.5 11.2 10.4 12.1 2.6 10.4 4.4 8.9 6.6 10.4 8.1 5.0 7.6 7.3 9.0 8.9 4.3 6.4 16.5 8.5 5.2 10.2 16.4 6.3 10.7 8.7 9.2 18.8 8.9 7.6 6.2 18.1 17.3 4.9 5.7 9.9 6.7 11.5 17.2 6.5 8.0 4.5 11.5 12.1 18.7 5.8 8.8 16.4 10.5 10.6 5.8 10.3 5.7 8.2 5.2 7.3 4.2 4.8 11.0 10.8 5.8 9.9 6.3 9.6 9.6 15.3 7.8 17.6 4.7 7.5 11.2 10.5 12.1 10.4 10.8 8.6 9.5 8.7 12.4 7.6 8.3 9.4 9.7 10.4 8.3 7.7 8.2 2.6 14.9 12.9 21.9 13.8 10.6 11.8 11.1 8.8 12.9 13.7 EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240598-133532120 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 65.6" "Cell line enhanced" "Detected in many" "A549: 12.6;HeLa: 35.3;RH-30: 12.0;U-87 MG: 12.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm Nucleoplasm "HPA004805: AB_10669750, HPA038771: AB_10671865, HPA038772: AB_10673119" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (2.04e-9)" "unprognostic (1.64e-1)" "unprognostic (3.08e-2)" "unprognostic (3.44e-2)" "unprognostic (7.21e-2)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (8.27e-4)" "unprognostic (1.82e-3)" "unprognostic (6.67e-2)" "unprognostic (9.55e-2)" "unprognostic (2.51e-2)" 1.6 3.0 1.2 0.2 1.3 0.1 2.4 0.4 1.2 9.7 0.6 2.5 11.1 0.4 2.6 1.9 0.7 8.3 0.7 6.2 1.5 1.2 6.1 0.4 2.0 0.2 2.1 0.8 1.6 0.4 0.2 7.2 0.2 3.5 6.6 0.4 2.7 0.8 13.9 65.6 0.4 0.5 1.9 3.5 0.6 0.7 7.4 1.4 1.8 2.5 5.5 0.7 2.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 1.2 0.0 0.0 0.0 0.0 0.0 10.1 0.2 1.5 0.0 0.0 0.0 10.0 0.0 0.0 7.6 3.2 0.0 0.0 9.9 1.3 35.3 0.0 0.3 0.0 3.4 2.6 0.0 7.3 2.2 0.0 0.0 5.4 4.0 0.0 0.0 0.0 0.0 0.7 0.1 12.0 0.0 0.0 1.9 1.8 2.0 0.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 9.0 3.6 1.6 0.0 12.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.4 1.2 1.5 1.2 2.1 0.8 3.5 1.4 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747822-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favourable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 13.4 5.7 5.5 6.1 13.4 1.8 5.2 6.0 5.0 9.7 6.7 1.4 16.8 2.5 6.5 19.3 8.2 4.6 5.3 4.6 4.8 4.8 7.2 3.6 12.2 1.9 4.9 2.2 7.2 3.0 18.5 15.9 5.7 3.1 6.8 3.6 5.0 4.5 21.9 5.0 6.6 3.5 7.2 6.2 8.1 4.1 15.9 2.6 3.9 10.2 12.8 2.8 7.7 9.0 10.5 5.4 8.0 5.1 1.2 2.8 1.1 4.6 1.6 5.7 9.0 3.4 5.2 3.6 5.6 5.5 3.3 3.9 9.5 2.9 7.5 3.5 6.7 3.3 3.1 7.0 7.5 3.1 4.2 4.9 7.2 3.4 2.3 2.7 4.2 3.1 3.9 7.9 9.0 4.9 6.1 5.6 4.2 1.3 2.1 0.8 0.8 3.3 1.7 5.5 44.2 3.2 1.6 1.9 2.8 9.2 0.5 6.0 2.2 1.2 7.2 6.4 4.9 3.2 4.4 4.8 7.1 2.9 4.0 0.8 3.0 8.0 5.1 5.4 1.7 3.1 2.8 10.5 1.0 1.8 2.8 3.8 1.6 2.0 0.4 1.2 2.4 5.4 2.1 1.1 5.5 13.4 6.0 4.2 4.8 4.8 4.9 2.2 3.1 2.6 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 60.8;lymphoid tissue: 49.7" "Cell line enhanced" "Detected in many" "HEL: 20.9;HL-60: 18.6;HMC-1: 39.8;NB-4: 24.4;THP-1: 36.6;U-937: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Group enriched" "Detected in many" 4 "dendritic cells: 32.6;granulocytes: 60.8;monocytes: 30.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavourable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 14.9 3.4 4.8 9.7 4.1 38.3 12.7 2.4 5.7 6.8 5.4 3.2 4.7 3.0 7.4 5.6 4.9 7.6 7.3 7.9 4.2 2.2 5.2 11.8 12.7 23.3 3.7 0.9 6.4 3.7 1.8 2.7 8.1 7.2 7.7 2.4 5.3 33.8 6.3 3.4 3.5 5.2 5.4 6.9 49.7 4.3 3.2 4.7 3.1 7.2 4.1 4.5 7.2 9.4 1.1 32.6 60.8 30.5 9.3 0.1 13.8 0.1 0.2 0.3 3.5 1.0 3.1 6.0 0.9 0.0 1.7 1.0 0.8 0.0 2.2 0.1 2.0 0.5 0.6 0.1 0.5 1.1 0.3 20.9 0.0 3.7 2.0 18.6 39.8 3.0 0.0 2.6 0.0 10.5 0.6 0.0 0.0 6.8 0.5 24.4 1.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 36.6 8.3 0.0 3.6 0.1 0.0 0.0 2.6 0.8 0.1 15.8 0.8 10.4 30.5 60.8 0.1 17.6 0.0 1.1 0.0 0.0 32.6 0.9 0.0 0.0 20.0 9.3 7.3 12.9 0.0 13.8 4.8 4.1 2.4 5.7 4.2 2.2 3.7 0.9 7.2 4.7 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38411138-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 109.2;BJ hTERT+: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved 120000000 "CAB033614: AB_783377, HPA056402: " "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 41.1 8.6 12.5 14.5 12.2 7.2 39.5 45.0 10.5 36.0 31.5 10.1 11.6 5.5 29.3 20.6 22.9 29.4 32.4 31.7 12.8 10.1 11.8 5.4 18.6 9.7 11.4 14.3 42.0 51.2 11.5 22.3 28.4 20.0 28.2 10.8 35.8 14.0 31.6 12.0 12.9 14.4 52.4 15.6 4.5 16.4 16.4 8.5 11.3 12.6 13.0 9.8 39.6 41.2 1.6 0.7 1.8 1.1 0.8 5.7 0.7 2.4 9.3 40.3 109.2 25.1 17.9 26.6 24.8 49.8 17.3 18.0 6.0 1.4 0.3 6.9 23.8 0.0 19.1 1.2 20.0 6.5 4.2 0.0 1.5 5.9 14.1 5.8 0.1 16.2 0.1 14.0 2.8 16.6 2.2 0.1 8.1 2.8 17.0 1.9 28.4 3.9 15.7 4.2 0.0 8.4 0.0 1.6 3.6 4.4 0.2 1.0 2.2 1.1 10.4 11.3 6.2 31.2 5.9 0.4 0.7 0.0 13.4 0.3 5.9 1.4 1.1 0.4 5.7 0.3 3.9 0.7 2.7 3.7 0.1 1.6 1.5 4.1 1.8 0.8 0.5 0.7 2.2 0.7 12.5 12.2 45.0 10.5 12.8 10.1 11.4 14.3 20.0 8.5 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478334-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.8" "Cell line enhanced" "Detected in some" "AN3-CA: 57.8;BEWO: 19.4;CACO-2: 15.1;HaCaT: 17.4;HAP1: 18.7;NTERA-2: 18.5;T-47d: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 10.8;eosinophil: 4.6" "Lineage enriched" "Detected in single" 35 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" 500000 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favourable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favourable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 2.1 8.8 16.4 3.0 30.3 0.0 9.9 15.8 21.3 6.8 14.1 55.7 5.6 4.2 22.0 6.6 10.2 12.5 12.5 1.4 20.6 11.1 11.4 16.1 13.1 1.0 41.2 13.3 7.4 12.8 25.5 2.5 6.2 30.2 11.7 8.7 16.4 23.8 24.3 0.4 45.4 4.7 18.3 74.8 0.5 9.3 2.9 32.1 0.8 23.4 1.6 3.4 6.9 8.5 0.1 0.1 10.8 0.1 0.1 0.3 0.0 2.2 0.1 9.0 57.8 0.0 0.0 19.4 0.1 0.0 0.0 0.0 15.1 0.3 0.0 4.1 0.9 17.4 18.7 4.0 0.0 0.0 4.0 0.0 0.0 0.3 0.4 0.0 3.8 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 18.5 0.0 0.0 0.0 2.2 5.6 4.9 0.1 0.1 0.1 10.6 0.0 15.5 0.0 0.0 0.1 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 10.8 0.1 4.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 16.4 30.3 15.8 21.3 20.6 11.1 41.2 13.3 30.2 32.1 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease mutation, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 131.7" "Cell line enhanced" "Detected in many" "CACO-2: 19.1;HaCaT: 14.9;Hep G2: 32.1;NTERA-2: 15.6;RT4: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 670000 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: " "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.5 1.5 24.7 1.7 30.3 1.6 4.2 10.2 22.0 4.1 4.9 15.8 3.4 9.9 1.8 2.7 26.9 2.0 5.0 2.0 21.6 11.7 9.6 7.4 4.5 1.3 17.6 21.5 1.1 23.0 1.2 3.0 5.6 15.1 3.7 3.8 1.7 3.8 9.0 1.7 131.7 7.4 1.3 9.0 2.1 4.9 8.1 10.6 0.1 1.3 8.5 7.3 8.5 10.1 0.1 0.6 0.1 0.1 0.2 0.3 0.0 0.0 1.5 9.0 2.6 0.0 0.1 9.2 1.0 0.1 0.4 0.2 19.1 0.4 0.0 7.6 0.3 14.9 2.6 0.1 0.1 0.1 9.6 5.9 1.5 32.1 0.0 0.0 0.1 0.0 5.0 0.1 0.0 0.0 6.4 0.0 0.0 9.5 0.3 0.2 15.6 0.0 0.5 0.5 0.1 1.3 19.1 2.6 0.7 0.8 1.6 0.0 8.9 1.1 0.4 0.0 0.9 0.2 0.6 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.6 0.1 0.0 24.7 30.3 10.2 22.0 21.6 11.7 17.6 21.5 15.1 10.6 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086886-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 33.6;kidney: 37.7;liver: 45.3" "Group enriched" "Detected in many" 4 "CACO-2: 42.0;Hep G2: 42.0;RH-30: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "neutrophil: 3.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" 4300000 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 0.5 5.7 0.7 14.3 0.6 0.1 1.6 2.6 0.5 2.8 10.4 0.9 0.7 13.5 0.9 4.8 1.6 1.7 33.6 0.7 0.8 0.3 37.7 45.3 25.3 2.5 0.7 1.0 13.6 26.0 0.0 0.7 1.3 0.8 4.0 3.7 2.0 1.6 0.3 4.3 0.5 17.3 1.6 0.8 11.2 5.4 2.9 0.4 0.3 0.8 2.3 0.7 1.9 3.6 1.1 0.9 3.0 1.1 0.4 0.4 0.0 0.7 11.8 0.2 2.9 0.0 0.0 5.8 0.0 0.0 0.0 0.0 42.0 1.6 1.2 5.5 0.0 0.6 2.3 0.4 0.0 0.7 2.8 0.1 0.6 42.0 1.3 0.1 1.0 0.2 0.0 2.1 0.0 0.0 3.9 0.1 0.9 9.6 0.0 0.8 7.1 1.0 1.9 67.6 7.1 5.7 0.1 0.4 0.7 0.4 3.0 1.4 2.9 0.6 0.2 0.0 5.7 0.0 0.1 0.4 0.4 0.7 0.0 0.2 0.5 1.5 1.1 0.4 0.4 0.3 0.3 1.1 0.4 0.0 0.1 0.6 0.4 0.4 3.0 0.4 0.3 0.9 0.2 0.0 0.7 0.6 2.6 0.5 0.8 0.3 0.7 1.0 0.8 0.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635277 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 20.8;blood: 68.0;bone marrow: 73.6;lung: 30.9;lymphoid tissue: 54.3" "Group enriched" "Detected in some" 4 "Daudi: 29.4;U-266/70: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 20.8 2.6 2.2 23.6 4.5 73.6 5.6 1.1 4.2 2.9 2.8 1.5 4.2 1.6 4.0 2.3 2.2 6.3 5.3 8.5 2.6 2.3 3.0 4.2 30.9 34.1 6.6 1.7 1.9 2.4 0.4 1.2 3.3 4.2 2.5 1.8 2.1 2.9 2.6 4.4 1.7 3.7 6.4 4.8 54.3 2.5 2.6 4.1 1.9 2.9 2.5 7.8 5.1 6.1 13.3 28.9 40.8 68.0 36.3 29.6 55.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 54.6 0.7 2.2 0.0 6.7 0.0 3.1 52.4 32.3 29.6 68.0 1.7 7.7 2.6 13.6 28.9 13.3 1.3 12.8 40.8 36.3 55.6 1.3 0.1 55.0 2.2 4.5 1.1 4.2 2.6 2.3 6.6 1.7 4.2 4.1 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related tyrosine kinase 1" P17948 13 28300344-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "placenta: 155.3" "Cell line enhanced" "Detected in some" "BJ: 17.0;BJ hTERT+: 13.5;HMC-1: 84.6;HUVEC TERT2: 15.3;WM-115: 30.3" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.1;naive B-cell: 3.7;neutrophil: 2.1" "Group enriched" "Detected in many" 5 "B-cells: 3.7;granulocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" 875697 54000 "Plasma membrane, Actin filaments" "CAB068189: , CAB068190: , HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 18.9 4.0 9.9 4.0 14.3 1.2 13.5 8.0 15.9 7.1 4.6 3.5 1.7 3.5 7.2 2.2 3.4 4.0 6.9 18.3 11.4 7.3 10.3 7.6 12.3 2.5 10.3 3.2 5.1 5.4 13.4 3.7 155.3 13.8 5.1 3.1 9.1 3.0 5.0 12.5 2.6 3.4 7.3 9.6 7.2 4.6 6.8 10.2 0.0 19.1 3.8 2.8 7.6 9.2 3.7 0.5 2.1 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 17.0 13.5 6.2 3.6 0.0 0.0 0.0 0.0 2.2 0.0 1.6 0.0 11.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 84.6 0.1 0.0 0.0 0.2 15.3 0.4 0.0 0.0 0.0 1.0 0.8 9.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 30.3 0.2 0.1 0.1 0.1 0.1 0.0 1.1 0.1 0.1 0.0 3.7 0.4 0.4 2.1 0.2 0.1 0.5 0.2 0.2 9.9 14.3 8.0 15.9 11.4 7.3 10.3 3.2 13.8 10.2 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.9;brain: 19.3;lymphoid tissue: 15.0" "Group enriched" "Detected in some" 11 "REH: 27.8;THP-1: 17.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 19.3" "Group enriched" "Detected in some" 11 "myeloid DC: 29.9;plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 16 "dendritic cells: 29.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" 180000 "Endoplasmic reticulum" "HPA047539: " "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.9 0.6 0.6 7.2 1.1 7.5 2.6 19.3 3.5 0.9 1.2 0.1 0.1 0.4 0.8 0.8 1.0 1.2 4.6 0.5 0.9 1.7 2.8 0.7 2.7 15.0 1.8 1.1 0.5 5.7 0.0 0.4 0.0 7.4 0.6 1.4 0.1 2.3 0.6 0.4 1.2 3.0 1.3 4.4 8.8 0.9 1.2 0.0 8.2 0.6 0.0 5.8 2.4 0.7 0.1 29.9 1.4 1.8 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.5 0.0 27.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 1.4 0.0 0.3 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 0.0 0.8 0.0 12.1 0.0 1.2 0.6 1.1 19.3 3.5 0.9 1.7 1.8 1.1 7.4 0.0 FLT4 "PCL, VEGFR3" ENSG00000037280 "Fms related tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 56.3" "Cell line enhanced" "Detected in some" "AN3-CA: 8.3;BEWO: 10.2;HEK 293: 12.6;HL-60: 7.4;HUVEC TERT2: 8.1;T-47d: 12.0;TIME: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "MAIT T-cell: 7.7" "Lineage enriched" "Detected in single" 35 "T-cells: 7.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted to blood" 270000000 "Plasma membrane" "Nucleoplasm, Cell Junctions" "CAB000099: , HPA046519: , HPA067906: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 14.8 7.1 1.6 4.9 6.0 0.7 28.5 1.3 2.7 6.3 7.3 1.9 2.1 3.1 7.3 6.2 5.7 9.2 5.3 6.4 1.7 0.9 11.7 10.2 14.1 23.6 2.0 0.8 5.8 2.3 2.3 6.2 56.3 2.1 4.9 1.4 6.7 3.3 4.4 4.8 2.8 4.7 4.7 1.5 14.5 2.4 3.5 2.0 0.3 19.4 4.4 2.3 6.1 14.7 0.0 0.1 0.2 0.0 0.0 7.7 0.2 0.1 2.0 2.7 8.3 0.0 0.0 10.2 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.8 0.1 0.3 2.8 0.1 0.2 0.1 12.6 1.0 0.4 0.4 0.1 7.4 0.2 0.2 0.0 0.1 0.3 8.1 0.3 0.3 1.7 4.5 0.1 0.4 5.8 0.5 6.5 0.0 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.0 12.0 0.2 12.7 0.1 5.9 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.9 0.0 7.7 0.0 0.4 1.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 1.6 6.0 1.3 2.7 1.7 0.9 2.0 0.8 2.1 2.0 FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060758 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.4" "Cell line enhanced" "Detected in many" "RT4: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB025217, HPA030479" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB025217: , HPA030479: " "unprognostic (7.70e-3)" "unprognostic (1.99e-2)" "unprognostic (1.11e-1)" "unprognostic (4.68e-3)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (4.23e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "prognostic favourable (9.66e-7)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" 1.5 2.2 0.8 3.0 1.3 1.3 2.6 0.5 0.8 6.4 21.4 0.2 10.2 6.8 1.6 9.0 10.5 2.8 7.3 3.3 1.2 0.8 23.7 19.6 5.6 0.6 1.5 0.5 2.4 5.9 0.3 3.8 2.7 0.8 4.1 5.5 0.8 9.2 6.1 2.9 2.0 41.4 2.5 2.4 1.0 5.5 1.8 0.5 1.2 1.0 5.2 7.4 5.0 3.6 2.2 1.2 3.8 1.2 1.4 2.3 0.3 3.2 5.3 0.8 1.3 0.4 0.4 1.0 0.8 0.2 0.1 0.1 4.1 5.1 1.3 4.9 0.8 7.7 0.4 1.5 0.2 4.4 0.5 1.8 4.6 3.5 0.3 1.2 1.1 0.3 2.2 0.5 0.6 0.3 0.9 3.3 1.3 1.8 1.0 0.8 1.4 0.9 1.5 4.6 1.6 6.5 10.1 1.1 1.2 1.1 6.8 0.7 2.1 1.0 1.3 1.5 1.6 1.2 0.8 5.0 3.5 2.3 1.5 0.8 1.0 3.2 1.0 1.0 1.9 0.6 2.3 1.1 1.4 1.7 0.4 2.2 1.1 1.4 3.8 1.4 1.2 1.2 1.0 0.3 0.8 1.3 0.5 0.7 1.2 0.8 1.5 0.5 0.8 0.5 FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 14.2;epididymis: 7.9;fallopian tube: 11.1;heart muscle: 6.3;retina: 11.4" "Cell line enhanced" "Detected in some" "BEWO: 6.6;HBEC3-KT: 2.8;Hep G2: 1.5;SCLC-21H: 2.8;SK-BR-3: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 7.6" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" 0.4 0.4 5.6 0.4 12.0 0.4 2.1 7.3 4.1 1.4 0.6 12.7 0.0 0.4 0.9 7.9 0.4 11.1 0.4 6.3 6.4 4.0 1.1 0.4 1.5 0.4 3.1 1.3 0.8 0.7 0.4 0.5 0.7 14.2 1.8 1.0 11.4 0.5 0.6 0.4 0.4 0.5 0.4 2.4 0.4 0.4 1.5 6.5 0.0 2.3 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 2.8 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 12.0 7.3 1.7 6.4 4.0 3.1 1.3 14.2 6.5 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "NK-cells: 15.3;T-cells: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" 2000000 "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: " "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favourable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavourable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 29.1 7.2 49.2 29.0 38.4 16.3 18.1 33.9 62.1 25.7 12.1 33.7 4.1 10.1 21.8 21.4 10.2 32.0 19.4 21.2 39.4 34.0 9.5 12.2 25.2 57.2 35.7 23.1 18.6 4.4 15.0 12.5 17.7 25.6 9.6 10.0 11.0 6.4 8.4 7.0 16.5 19.0 24.2 30.9 39.8 15.4 10.1 31.3 34.8 27.5 5.6 38.5 22.6 19.3 1.6 1.7 0.7 1.5 15.3 43.2 10.7 1.9 0.2 34.2 5.7 26.2 16.1 0.6 5.4 17.1 4.6 8.3 0.2 0.3 3.8 3.5 10.4 0.2 4.8 7.5 9.1 0.1 12.6 10.5 2.5 0.5 15.5 3.5 3.6 15.4 11.3 17.4 14.9 18.8 0.8 26.8 16.4 0.2 16.7 3.2 4.9 3.4 5.3 4.6 0.2 0.0 1.7 24.0 9.7 1.0 0.4 22.8 0.2 10.6 11.9 14.0 2.6 103.1 3.4 3.8 3.5 5.9 26.4 8.2 24.3 0.2 1.5 0.0 34.1 1.2 43.2 1.1 21.2 37.5 1.7 1.6 7.0 18.7 0.7 15.3 0.9 1.0 17.6 10.7 49.2 38.4 33.9 35.3 39.4 34.0 35.7 23.1 25.6 31.3 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052188-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 107.1;lymphoid tissue: 72.6" "Group enriched" "Detected in some" 8 "THP-1: 22.6;U-937: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 50.8;eosinophil: 62.5;intermediate monocyte: 96.5;myeloid DC: 31.6;neutrophil: 73.0;non-classical monocyte: 107.1" "Group enriched" "Detected in many" 15 "dendritic cells: 31.6;granulocytes: 73.0;monocytes: 107.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005195, HPA063768" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB005195: AB_631619, HPA063768: " "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavourable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 12.3 5.8 5.9 40.8 13.1 20.8 4.0 1.8 5.3 3.0 5.8 6.1 0.9 5.9 2.5 5.7 3.1 5.9 6.5 8.8 6.0 3.7 4.0 7.9 20.9 50.3 11.2 1.2 3.4 2.8 0.7 2.9 8.8 8.0 3.8 5.9 3.1 4.1 1.9 3.1 2.8 7.8 10.2 9.1 72.6 3.7 2.6 8.2 5.8 3.3 1.2 16.4 9.4 3.5 4.7 31.6 73.0 107.1 1.1 0.1 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 22.6 0.0 0.0 0.1 0.0 0.0 0.6 0.1 3.3 0.0 64.8 0.0 0.5 50.8 62.5 0.1 96.5 0.1 4.7 0.1 0.1 31.6 3.7 0.1 0.0 73.0 1.1 107.1 2.8 0.1 40.2 5.9 13.1 1.8 5.3 6.0 3.7 11.2 1.2 8.0 8.2 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648971-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.7" "Group enriched" "Detected in many" 5 "granulocytes: 7.7;T-cells: 2.9" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved Approved Vesicles 36000 Vesicles "CAB010268: AB_671792, HPA045563: " "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 8.4 12.7 11.5 5.9 13.5 16.3 18.5 23.0 15.7 15.3 13.4 10.4 22.7 4.2 15.3 16.3 9.2 18.9 7.7 11.6 11.7 7.3 17.0 2.0 11.0 4.9 8.0 11.8 23.2 22.5 4.7 13.8 17.5 9.5 21.7 7.2 16.7 12.5 23.2 9.1 13.0 7.5 18.1 8.0 7.3 10.7 12.0 11.5 10.7 16.1 7.0 5.6 12.8 21.6 1.0 0.4 7.7 0.6 1.0 2.9 0.7 3.3 16.5 11.6 0.2 5.8 4.2 7.7 3.7 7.4 1.2 1.1 7.1 8.8 0.8 10.7 7.2 15.8 5.1 15.0 1.0 0.0 5.2 12.5 18.5 14.2 5.1 6.6 1.3 6.6 7.1 2.1 10.2 4.1 0.6 2.9 5.7 23.4 2.5 4.4 10.8 0.9 4.0 9.0 3.0 3.5 20.3 3.9 17.3 26.7 1.5 14.4 8.1 3.1 11.3 1.1 15.0 3.0 5.8 1.0 4.4 2.7 2.2 4.9 2.8 4.0 0.6 1.8 0.9 0.6 0.6 0.4 0.8 0.3 0.4 1.0 2.9 1.0 7.7 1.0 0.5 0.3 0.0 0.7 11.5 13.5 23.0 15.7 11.7 7.3 8.0 11.8 9.5 11.5 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Predicted secreted proteins" Hormone "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 234.1" "Cell line enhanced" "Detected in some" "Karpas-707: 8.8;PC-3: 4.0;SCLC-21H: 8.0;SH-SY5Y: 7.2" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA028615 Enhanced "Secreted to blood" 566000 "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.1 0.4 0.1 1.1 0.2 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.1 0.3 0.1 1.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.1 0.1 9.6 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 1.1 0.1 234.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 2.4 0.3 5.7 1.2 1.3 2.9 1.1 0.3 1.0 0.2 0.7 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 1.7 0.2 2.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.3 0.0 0.1 1.9 1.3 0.9 0.0 0.0 0.0 0.1 8.8 0.0 1.5 0.3 1.5 0.0 4.0 1.3 0.0 0.2 0.2 0.5 8.0 7.2 0.1 2.4 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.7 3.1 0.2 0.1 2.0 0.0 0.8 0.5 0.0 1.8 1.2 1.8 0.3 2.4 2.3 0.3 2.4 2.1 2.9 5.7 1.3 0.3 0.3 2.0 1.1 0.1 0.2 0.2 0.6 0.1 0.0 0.1 0.1 0.1 0.1 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294034 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5" "Cell line enhanced" "Detected in many" "Karpas-707: 30.6;U-266/70: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 8.8;granulocytes: 5.1;monocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" 72000 Vesicles "Plasma membrane" "HPA036302: , HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.9 14.7 7.1 3.5 8.2 4.5 12.0 12.0 8.2 10.3 15.2 11.7 10.6 8.4 15.5 6.1 4.7 13.1 7.7 17.7 6.4 5.8 18.7 32.5 5.3 2.2 10.1 4.9 28.3 64.5 11.6 11.6 26.2 8.0 10.5 8.9 11.0 12.0 10.6 15.1 7.3 16.0 10.6 6.8 47.3 8.7 6.9 9.7 2.2 17.1 5.0 3.2 11.3 16.0 1.1 8.8 5.1 10.5 0.8 0.7 1.3 3.7 2.1 1.9 2.9 10.6 3.7 6.4 2.1 1.9 1.2 1.2 5.3 4.3 4.7 5.3 3.8 1.0 4.6 0.9 0.7 0.0 3.7 0.0 1.5 11.5 4.6 2.2 3.8 5.7 2.4 0.1 2.8 2.1 5.7 30.6 0.9 1.7 1.6 3.8 1.8 3.3 16.3 1.1 4.1 0.1 15.5 3.7 2.8 3.8 2.0 2.1 0.9 10.8 2.0 2.2 1.4 4.7 2.8 22.6 12.3 10.9 2.6 3.8 0.0 2.0 8.2 5.1 0.2 7.8 0.3 0.8 0.3 0.1 8.8 1.1 0.7 0.1 1.7 0.8 10.5 7.4 0.0 1.3 7.1 8.2 12.0 8.2 6.4 5.8 10.1 4.9 8.0 9.7 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859018 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.5;brain: 5.9;kidney: 8.3" "Group enriched" "Detected in some" 7 "SCLC-21H: 5.4;SH-SY5Y: 18.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA025285 Uncertain "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.9 5.5 0.0 0.3 5.9 0.1 0.8 1.9 1.4 1.9 0.1 0.0 0.0 0.1 2.7 0.1 0.1 0.6 0.3 1.9 0.5 1.3 8.3 0.1 0.1 0.4 0.8 0.6 0.3 0.9 0.1 1.7 0.4 5.6 2.7 0.1 2.1 0.6 0.5 0.4 0.1 0.2 0.3 0.0 0.2 3.0 4.2 0.4 0.3 0.3 0.0 0.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 1.4 0.5 1.3 0.8 0.6 5.6 0.4 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255191 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 28.0;lymphoid tissue: 60.5" "Cell line enriched" "Detected in some" 5 "MOLT-4: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 28 "gdT-cell: 13.8;MAIT T-cell: 9.1;memory CD4 T-cell: 19.5;memory CD8 T-cell: 18.9;naive CD4 T-cell: 28.0;naive CD8 T-cell: 22.8;NK-cell: 9.2;T-reg: 23.1" "Group enriched" "Detected in many" 29 "NK-cells: 9.2;T-cells: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 2.3 0.7 0.5 12.2 0.6 2.5 1.3 1.9 0.5 1.4 3.3 0.0 0.0 0.5 1.2 1.1 1.8 1.4 4.3 0.9 0.5 0.5 1.4 1.2 6.6 60.5 0.9 0.0 0.7 0.7 0.0 0.9 0.1 0.3 1.1 1.3 1.5 3.5 1.1 0.5 1.0 8.9 0.4 1.2 10.7 2.3 1.4 0.0 60.3 1.6 2.7 24.3 4.1 1.3 0.0 0.0 0.4 0.6 9.2 28.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 3.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 9.1 0.0 19.5 18.9 0.0 0.0 28.0 22.8 0.4 9.2 0.6 0.0 23.1 13.6 0.5 0.6 1.9 0.5 0.5 0.5 0.9 0.0 0.3 0.0 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-64966504 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved "CAB013088: " "prognostic favourable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favourable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favourable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 46.7 20.4 15.5 31.1 16.5 21.2 56.6 24.3 20.4 27.3 27.1 16.3 16.5 13.8 28.2 22.0 27.0 20.7 27.7 27.3 15.3 16.5 31.4 38.3 36.5 61.4 15.6 14.1 33.3 29.1 28.3 39.8 22.9 25.1 26.0 22.2 18.1 19.8 21.3 45.1 29.7 29.3 30.7 16.3 52.7 20.9 17.3 15.0 62.7 29.0 17.9 42.5 37.2 29.3 20.2 15.4 34.9 17.1 68.1 27.5 25.8 10.9 14.4 6.0 0.6 69.4 39.3 7.8 17.2 25.4 14.3 16.9 4.7 6.1 16.7 13.4 30.5 6.2 4.0 13.3 20.4 22.1 6.4 22.7 7.5 10.2 25.6 8.7 15.8 34.5 18.5 21.6 22.6 44.6 8.2 17.9 15.8 6.3 4.7 5.8 4.1 8.6 6.8 17.3 6.1 36.9 19.4 4.2 12.7 23.6 11.1 10.1 23.5 5.4 40.4 17.2 7.7 38.9 9.1 11.2 5.1 13.3 16.0 11.5 7.7 31.2 10.9 31.5 22.8 15.2 27.5 20.2 22.0 25.7 15.4 16.1 24.3 20.7 34.9 68.1 17.1 10.5 26.5 25.8 15.5 16.5 24.3 20.4 15.3 16.5 15.6 14.1 25.1 15.0 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "ASC diff: 18.9;HDLM-2: 26.7;HEL: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: , HPA043870: " "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.4 1.4 2.5 18.9 4.9 0.4 3.4 2.9 2.6 1.7 0.1 0.8 0.1 0.8 2.0 0.8 1.5 2.1 1.9 26.7 0.5 54.8 2.9 0.7 3.9 3.7 2.8 4.0 0.9 1.1 1.8 2.4 3.9 6.4 4.7 0.9 0.9 5.2 1.3 1.7 1.9 2.7 0.7 2.0 1.3 1.6 0.9 1.0 1.5 1.0 0.7 6.5 5.0 4.0 1.3 4.1 2.4 1.2 2.2 0.5 5.2 1.8 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 68.3" "Cell line enhanced" "Detected in some" "HDLM-2: 20.1;HEL: 9.0;HMC-1: 9.2;Karpas-707: 23.5;U-266/70: 9.1;U-266/84: 13.5;U-937: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA070314: " "unprognostic (5.59e-3)" "prognostic favourable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.8 1.7 4.0 24.5 8.5 12.0 2.7 2.4 3.1 1.9 2.3 1.0 0.0 2.2 1.7 2.0 2.5 3.5 3.6 4.3 2.7 2.8 3.8 2.0 8.4 68.3 7.5 0.0 11.0 2.0 0.4 2.3 4.1 5.3 3.0 2.4 1.6 6.1 1.5 0.7 1.3 9.5 2.5 8.4 36.1 3.2 1.8 5.8 20.9 3.4 1.7 28.8 5.3 2.4 7.4 4.5 16.9 9.6 8.4 15.0 6.8 0.1 0.3 0.3 1.0 0.4 1.4 0.2 0.5 0.0 0.0 0.1 0.0 0.9 0.4 1.9 0.4 0.1 0.0 0.2 0.0 20.1 0.0 9.0 0.0 0.8 0.7 0.0 9.2 5.0 0.2 0.0 0.0 0.2 0.0 23.5 0.0 0.4 3.6 0.0 0.1 0.7 4.6 0.0 0.4 0.5 0.0 0.0 0.3 0.1 0.2 0.0 2.0 1.3 0.4 0.0 0.4 0.0 0.0 9.1 13.5 2.5 0.1 13.7 0.2 1.2 4.9 0.2 12.6 9.6 14.5 6.5 15.0 13.1 4.5 7.4 14.9 13.0 16.9 8.4 8.8 3.7 11.8 6.8 4.0 8.5 2.4 3.1 2.7 2.8 7.5 0.0 5.3 5.8 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078259-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 31.8;TIME: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004028 Enhanced Supported "Plasma membrane" "Intracellular and membrane" 7400000 "Plasma membrane" "CAB004028: AB_2212507" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavourable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 19.7 6.2 1.8 4.4 3.1 0.4 20.5 1.1 2.2 11.4 6.0 1.8 11.5 2.3 28.8 10.2 5.2 9.5 6.2 12.1 2.3 1.7 7.8 10.4 13.2 14.1 3.1 2.9 6.0 8.1 8.0 6.8 34.5 3.9 9.5 1.4 27.6 7.1 10.3 5.3 3.0 3.8 7.7 2.6 4.4 4.2 5.3 1.2 0.5 20.0 5.3 3.0 4.4 12.0 0.1 0.1 0.7 0.0 0.2 0.2 0.1 0.0 0.0 1.7 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 0.2 31.8 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.8 3.1 1.1 2.2 2.3 1.7 3.1 2.9 3.9 1.2 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 65.5" "Group enriched" "Detected in some" 13 "HEL: 47.7;HMC-1: 100.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7" "Group enriched" "Detected in many" 6 "granulocytes: 12.7;NK-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" 48000000 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: , CAB072867: , HPA004471: AB_1078431, HPA073252: " "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favourable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 8.1 1.6 9.5 6.6 11.8 3.7 65.5 18.3 12.0 12.1 10.3 6.5 10.2 5.8 8.9 4.2 9.9 2.5 15.5 2.4 36.0 4.4 9.4 1.1 13.8 3.8 3.6 6.0 28.5 2.1 1.3 2.3 6.2 5.7 9.6 10.4 20.7 12.9 6.9 1.3 14.6 8.9 10.2 3.9 3.2 12.8 4.0 4.5 0.4 28.9 4.3 4.9 9.8 12.5 0.0 1.8 12.7 0.9 9.7 1.9 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.6 0.9 2.5 3.2 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 2.1 0.0 1.1 47.7 0.0 0.0 0.0 0.0 100.2 0.0 0.0 0.0 0.0 5.6 0.6 0.1 0.0 0.0 0.2 0.4 1.3 0.0 0.1 0.0 0.0 0.0 4.7 1.2 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 12.7 0.0 10.0 0.1 0.0 1.9 0.0 0.3 0.7 1.8 0.0 0.0 0.0 0.8 9.7 0.9 0.0 0.0 0.1 9.5 11.8 18.3 12.0 36.0 4.4 3.6 6.0 5.7 4.5 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 112.2;lymphoid tissue: 153.0" "Group enriched" "Detected in some" 6 "MOLT-4: 98.9;U-698: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "gdT-cell: 83.4;MAIT T-cell: 77.5;memory CD4 T-cell: 86.1;memory CD8 T-cell: 90.2;naive CD4 T-cell: 97.0;naive CD8 T-cell: 91.3;NK-cell: 42.8;T-reg: 112.2" "Group enriched" "Detected in many" 13 "NK-cells: 42.8;T-cells: 112.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favourable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favourable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favourable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavourable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 2.6 0.7 0.4 28.2 0.5 3.8 1.3 0.3 0.5 1.7 3.9 0.5 0.9 2.2 1.1 4.5 2.3 1.6 3.8 1.0 0.4 0.4 3.0 2.3 6.6 34.9 0.9 0.5 1.2 0.8 0.0 0.8 0.7 0.6 2.2 1.9 1.3 8.4 1.3 0.9 1.0 16.5 0.7 1.0 28.9 3.5 0.7 0.5 153.0 2.9 1.5 27.1 5.8 2.1 6.1 0.5 2.5 0.3 42.8 112.2 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 12.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 57.0 0.0 0.0 0.0 0.6 0.3 0.4 83.4 0.3 77.5 4.0 86.1 90.2 0.3 6.1 97.0 91.3 2.5 42.8 0.3 0.5 112.2 109.3 0.4 0.5 0.3 0.5 0.4 0.4 0.9 0.5 0.6 0.5 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106885-98209633 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: " "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavourable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favourable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 5.1 10.3 13.7 5.6 21.3 17.3 5.6 16.6 34.3 7.3 13.8 6.1 5.6 12.6 6.1 6.3 12.7 6.4 7.9 16.9 11.0 10.1 10.1 8.5 10.0 5.1 7.5 18.9 8.0 21.0 22.2 10.0 4.8 13.2 7.9 11.8 5.4 10.5 6.5 17.5 11.5 13.8 5.7 5.5 6.8 9.4 8.0 6.9 7.2 8.7 5.7 7.4 8.3 8.1 0.6 0.7 4.8 0.9 0.3 1.6 0.5 9.9 11.7 9.1 9.3 4.9 3.9 8.5 4.1 4.5 4.1 4.9 9.2 9.1 5.2 11.9 5.3 10.9 10.5 6.3 6.4 7.4 7.4 3.5 10.5 9.2 6.0 6.3 6.4 2.7 8.8 8.4 11.4 6.1 9.2 11.1 3.7 13.5 6.6 3.8 11.1 5.7 7.3 6.2 10.3 6.8 17.5 6.5 13.1 8.3 15.2 6.0 4.2 2.6 7.4 8.5 14.0 16.9 9.4 4.9 8.6 10.5 5.7 5.0 10.1 1.2 0.6 0.5 0.8 0.3 0.5 0.6 0.9 0.9 0.3 0.6 1.1 1.6 4.8 0.3 0.9 0.7 0.8 0.5 13.7 21.3 16.6 34.3 11.0 10.1 7.5 18.9 13.2 6.9 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513189 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.1" "Cell line enhanced" "Detected in many" "HMC-1: 8.4;SK-BR-3: 10.0;U-266/70: 9.3;U-266/84: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: " "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favourable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 1.3 4.4 19.8 2.3 28.6 2.0 2.0 20.0 38.1 2.0 1.5 6.0 0.2 6.2 1.4 1.5 2.3 1.6 1.9 1.7 17.2 11.1 2.5 1.3 3.2 2.2 6.5 23.8 1.3 2.1 8.5 6.1 2.1 12.5 3.5 1.2 1.6 5.2 3.1 1.2 2.4 4.0 1.2 6.6 1.8 2.9 1.5 10.3 0.0 2.3 0.0 2.2 1.6 1.2 0.0 0.0 0.0 0.2 0.0 0.4 0.1 4.5 3.0 0.3 0.0 0.0 0.0 4.4 0.0 0.2 0.0 0.1 2.2 3.6 1.6 1.2 0.0 2.1 0.3 1.6 0.0 0.0 1.2 0.2 0.3 0.7 0.0 0.0 8.4 0.2 0.9 0.0 0.0 0.1 1.4 2.8 0.0 3.0 0.6 0.8 1.1 0.9 3.8 0.0 1.3 1.1 0.7 0.7 2.8 0.1 10.0 0.0 3.8 0.2 0.1 0.0 0.8 0.1 0.0 9.3 7.5 0.4 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 19.8 28.6 20.0 38.1 17.2 11.1 6.5 23.8 12.5 10.3 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503638-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1" "Cell line enhanced" "Detected in some" "HEL: 5.3;NB-4: 10.3;RH-30: 5.0;THP-1: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 8.3;plasmacytoid DC: 7.0" "Group enriched" "Detected in many" 10 "dendritic cells: 7.0;T-cells: 8.3" "Low region specificity" "Detected in many" HPA059545 Uncertain Approved Vesicles Vesicles "HPA059545: " "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 1.0 0.5 0.5 5.1 1.6 3.1 0.5 2.0 3.2 0.6 8.2 0.5 1.9 10.6 1.3 1.1 1.2 0.3 2.0 2.2 0.5 0.1 3.5 4.3 15.1 0.6 0.5 0.5 1.0 0.5 1.0 0.7 8.9 0.5 0.7 4.8 4.3 11.7 0.5 2.0 0.9 10.7 0.5 0.5 5.5 8.3 2.4 0.8 0.5 0.7 0.5 2.2 0.6 0.7 0.7 7.0 0.0 0.0 0.0 8.3 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.6 0.9 1.3 2.4 0.0 0.0 0.1 0.7 0.0 2.9 0.0 0.4 0.2 1.4 5.3 0.0 0.0 2.3 0.0 0.0 0.4 0.4 0.0 0.1 0.0 2.0 0.0 2.0 0.0 0.0 10.3 0.4 0.2 0.2 5.0 0.1 0.0 0.0 0.5 3.3 0.1 0.2 0.0 0.2 15.8 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.6 0.0 8.3 0.7 0.5 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.2 0.5 1.6 2.0 3.2 0.5 0.1 0.5 0.5 0.5 0.8 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879813-56014168 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.9" "Cell line enhanced" "Detected in many" "HEL: 56.8;HMC-1: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" 11000000 "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavourable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 8.8 6.8 4.5 34.0 6.3 33.6 11.1 9.5 4.1 5.3 10.5 5.8 7.2 15.6 3.4 7.8 7.2 6.7 13.7 8.9 4.8 3.6 6.1 13.8 34.6 70.9 7.7 2.1 5.3 9.8 3.1 4.9 19.1 5.6 5.7 6.6 6.3 14.9 8.5 2.7 3.4 16.2 6.6 8.5 69.4 7.4 3.6 5.1 3.8 9.4 5.3 25.8 10.7 7.5 8.4 9.2 36.8 26.5 1.9 0.9 2.7 12.6 7.5 1.7 0.3 0.1 0.0 13.7 9.7 14.2 6.1 4.3 5.2 4.4 12.2 4.3 3.8 5.9 7.1 7.2 5.2 19.8 7.1 56.8 2.3 1.8 1.9 5.7 57.7 0.3 2.5 0.1 4.4 8.2 30.0 26.5 0.9 0.7 0.0 6.0 10.9 0.8 0.9 2.8 1.5 3.9 6.0 1.1 22.0 4.8 0.0 2.0 1.1 13.4 9.6 0.0 2.8 0.0 4.4 8.9 3.2 27.6 0.6 11.3 0.4 2.1 7.2 12.3 0.9 16.8 0.7 8.2 0.2 0.3 6.4 8.4 0.1 0.4 36.8 1.9 26.5 9.2 0.0 2.7 4.5 6.3 9.5 4.1 4.8 3.6 7.7 2.1 5.6 5.1 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.1 15.6 31.5 13.1 19.0 14.3 18.2 24.1 20.6 26.2 23.4 23.5 27.3 30.5 29.9 19.8 29.6 29.4 35.2 30.8 24.5 17.5 9.8 16.4 12.7 15.4 12.9 14.6 11.0 21.8 18.9 28.1 20.4 17.3 39.0 38.1 12.8 10.3 16.8 16.1 13.7 11.7 19.5 27.1 25.4 14.3 19.4 10.8 19.5 15.3 20.2 13.8 11.0 28.1 34.1 20.9 24.0 35.7 24.2 43.0 19.4 36.0 22.8 15.9 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol Cytosol "CAB003835: AB_562312, HPA051993: " "unprognostic (4.39e-1)" "prognostic favourable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favourable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favourable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.2 40.0 21.9 30.7 30.3 36.6 21.9 23.9 32.0 32.7 29.7 34.6 19.7 31.0 22.6 27.2 26.2 17.1 25.5 25.4 26.3 20.8 11.3 21.8 38.2 46.5 20.8 23.9 40.4 24.9 22.9 30.6 28.9 21.6 61.3 27.5 45.4 41.1 29.2 25.1 29.1 31.5 14.4 35.4 28.5 23.3 29.7 29.6 21.9 30.4 74.5 23.4 35.7 25.5 26.9 23.3 68.6 36.8 61.7 37.3 21.7 41.7 37.5 45.9 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.6 22.0 2.9 13.3 17.8 11.4 11.1 33.6 36.5 26.8 24.7 24.3 14.0 19.6 13.7 52.5 21.5 9.3 29.8 19.1 20.3 17.0 11.4 12.6 22.0 5.5 14.9 23.4 8.8 8.5 36.5 11.0 12.0 2.2 9.8 22.3 21.5 7.4 14.2 8.4 12.6 15.5 18.9 14.5 15.1 22.9 8.0 2.8 12.4 13.4 23.3 6.7 5.1 10.9 25.5 20.8 27.2 21.6 12.3 6.2 25.2 24.6 12.9 13.1 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 17.9 15.5 20.4 10.5 11.3 14.7 13.0 12.3 16.2 14.0 13.4 9.2 6.2 7.5 10.0 19.1 12.1 17.7 17.1 21.1 13.2 20.8 8.3 9.1 17.3 13.3 7.9 12.6 12.1 17.0 16.4 17.2 12.7 8.8 4.4 17.6 6.7 9.6 7.4 11.9 7.6 11.8 22.9 5.1 19.2 11.6 4.1 12.1 14.2 7.6 11.8 9.6 5.8 11.6 6.9 10.7 9.5 14.5 8.7 9.7 5.9 13.0 6.3 10.0 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favourable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.5 14.6 8.8 10.3 13.0 22.8 6.9 5.5 11.2 10.4 11.4 5.8 9.9 9.1 11.7 9.2 8.3 14.9 8.8 8.6 13.1 14.9 12.3 10.9 6.3 16.4 7.4 7.7 15.6 11.7 7.5 17.1 13.7 10.8 15.2 8.6 7.1 12.1 8.8 12.3 7.1 12.0 10.2 15.1 6.3 10.1 5.5 8.6 6.2 9.2 22.0 11.5 14.6 11.4 10.7 7.1 7.4 7.4 21.5 25.3 10.6 14.4 17.0 7.7 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell line enhanced" "Detected in many" "A549: 23.9;HUVEC TERT2: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favourable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favourable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 23.9 10.8 13.0 4.7 2.5 1.6 0.1 3.5 1.0 1.5 0.7 1.1 0.6 8.8 0.5 1.2 3.7 0.5 0.3 0.8 1.9 0.1 6.7 6.7 4.6 1.0 0.9 11.9 0.3 0.3 0.0 17.2 0.0 1.7 0.0 0.1 12.5 0.4 7.6 4.4 4.5 1.1 0.3 4.8 3.3 4.8 7.3 1.0 0.9 2.2 3.3 1.3 3.0 1.3 1.5 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: " "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favourable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favourable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.7 7.3 6.4 10.4 5.1 5.0 11.9 8.4 4.1 5.7 6.0 10.5 7.8 15.2 13.6 4.4 11.7 5.5 6.4 2.2 12.1 27.4 10.7 9.7 7.8 6.6 9.9 13.6 5.7 8.4 4.5 5.2 5.2 15.6 20.0 3.3 6.7 14.2 24.2 11.2 16.5 14.1 6.9 15.4 5.1 10.7 11.7 11.8 5.7 10.1 11.7 10.8 11.4 7.7 17.5 10.0 12.3 11.3 29.0 13.4 14.3 8.7 14.7 7.0 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.3;bone marrow: 19.1;brain: 27.4" "Cell line enhanced" "Detected in some" "HL-60: 40.7;HMC-1: 12.5;K-562: 18.1;MCF7: 13.2;NB-4: 28.4;SCLC-21H: 12.4;THP-1: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 19.4;NK-cell: 29.3" "Group enriched" "Detected in many" 54 "NK-cells: 29.3;T-cells: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favourable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 11.2 1.6 22.1 6.8 18.1 19.1 2.2 1.5 27.4 1.5 2.3 1.7 0.0 7.0 1.2 0.4 1.1 4.7 5.1 1.7 25.1 10.0 1.1 2.8 7.3 9.6 7.0 11.0 1.0 1.6 0.1 1.4 1.4 6.1 1.2 1.4 0.6 3.8 1.0 0.8 1.6 6.7 1.1 2.8 14.8 4.1 2.1 1.3 3.5 0.9 0.0 4.5 2.4 0.7 0.4 0.3 0.4 0.0 29.3 19.4 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 4.1 5.4 0.1 0.0 0.0 7.0 4.5 0.5 1.1 0.0 40.7 12.5 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 13.2 0.1 28.4 3.3 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 10.7 1.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 13.2 0.0 2.5 12.2 0.3 0.4 1.2 7.1 0.4 29.3 0.0 0.1 0.1 2.7 22.1 18.1 1.5 27.4 25.1 10.0 7.0 11.0 6.1 1.3 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898479-112029561 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 20.8;Hep G2: 21.6;HUVEC TERT2: 21.5;RT4: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 10.3;non-classical monocyte: 6.4" "Lineage enriched" "Detected in single" 48 "monocytes: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Approved Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" 29000000 "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: " "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favourable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favourable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 55.1 13.1 12.5 17.8 1.9 31.8 6.2 13.8 10.8 13.8 6.8 27.7 11.5 11.3 25.4 8.4 12.8 11.7 7.1 16.5 6.3 14.2 18.9 12.7 30.3 8.1 10.1 12.9 9.0 23.9 14.3 18.4 18.6 14.1 7.9 20.4 6.8 24.9 6.4 6.4 12.8 13.6 12.2 38.4 12.3 17.3 9.8 1.7 9.9 2.0 8.4 14.1 26.6 0.0 0.2 0.1 10.3 0.0 0.0 0.3 0.5 0.9 4.3 9.7 0.2 0.1 6.9 0.0 0.1 0.5 1.0 20.8 1.3 0.1 4.6 0.0 0.1 5.7 0.0 0.8 0.8 3.0 3.7 0.0 21.6 0.1 0.1 0.8 0.2 0.0 5.0 0.3 21.5 1.1 2.0 1.6 0.9 0.0 4.9 2.7 3.4 1.4 1.2 1.6 10.9 12.9 0.1 4.1 0.1 0.3 1.7 0.0 0.2 3.2 0.6 2.0 0.0 0.0 1.7 2.5 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 6.4 0.1 0.0 0.3 13.1 17.8 6.2 13.8 16.5 6.3 8.1 10.1 18.6 9.8 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672390-116798386 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 45.4;CAPAN-2: 49.6;EFO-21: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "amygdala: 3.5;basal ganglia: 9.9;cerebral cortex: 7.6;hippocampal formation: 8.0;olfactory region: 9.1" "Low region specificity" "Detected in many" "CAB005282, CAB018577, HPA055607" Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" 178550000 70000000 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: " "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 16.2 1.1 1.8 4.5 2.3 4.3 11.2 0.9 15.2 9.9 6.5 2.4 2.4 4.4 7.5 5.2 5.1 4.6 12.3 5.4 5.7 1.8 20.1 30.2 15.6 1.4 3.6 2.1 2.0 9.3 0.7 8.1 24.4 2.6 8.0 6.6 34.1 12.2 8.4 12.8 7.2 8.6 4.0 2.3 5.7 10.6 2.7 2.4 0.5 21.4 7.0 2.1 10.1 15.0 0.2 0.3 1.2 0.2 0.3 0.4 0.0 45.4 26.1 0.0 0.1 2.0 2.0 1.8 26.0 10.6 14.0 11.8 5.4 49.6 2.0 43.3 16.3 12.0 4.5 24.7 28.7 0.1 5.6 0.0 27.1 4.7 0.3 0.0 0.0 2.6 9.8 9.1 30.1 9.6 0.9 0.2 25.9 1.0 0.0 0.0 3.9 26.7 0.0 22.0 0.0 24.6 5.2 3.8 0.0 10.7 3.4 10.1 0.0 0.2 17.7 20.9 7.4 11.0 20.1 0.5 4.0 0.2 23.0 0.0 2.9 1.1 0.2 0.4 0.4 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 1.2 0.3 0.1 0.3 0.1 0.0 1.8 2.3 0.9 15.2 5.7 1.8 3.6 2.1 2.6 2.4 MST1R "CD136, CDw136, PTK8, RON" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.7;intestine: 34.3;skin 1: 28.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.3;HaCaT: 19.5;HBEC3-KT: 21.2;hTCEpi: 29.8;RT4: 22.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favourable (2.33e-5)" 1.7 0.1 0.4 7.5 0.6 0.0 2.4 0.5 0.7 1.8 20.5 0.7 2.0 11.2 1.2 1.3 6.1 0.6 27.7 0.9 0.5 0.1 1.4 0.4 5.0 1.1 0.4 0.6 0.5 4.1 0.0 1.3 0.8 0.9 1.7 9.7 2.5 2.1 0.4 0.5 28.7 34.3 0.7 0.4 0.6 19.1 1.9 0.4 7.7 1.3 6.0 4.5 4.3 3.5 0.2 0.0 0.0 0.0 0.6 2.1 0.0 12.7 4.9 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.2 35.3 0.5 3.1 0.2 19.5 0.0 21.2 0.0 0.3 0.3 0.0 8.4 0.3 0.3 0.0 0.4 0.1 29.8 0.1 4.2 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.1 10.3 0.8 0.0 0.3 13.0 22.8 0.3 0.0 3.6 8.2 0.0 6.5 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.4 0.6 0.5 0.7 0.5 0.1 0.4 0.6 0.9 0.4 MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883155-30030866 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516, HPA061399" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA034515: AB_10669726, HPA034516: AB_10669727, HPA061399: " "unprognostic (4.39e-3)" "unprognostic (7.84e-2)" "unprognostic (2.46e-2)" "unprognostic (1.76e-2)" "unprognostic (5.61e-2)" "unprognostic (4.51e-3)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (3.42e-1)" "unprognostic (4.39e-1)" "unprognostic (8.33e-4)" "unprognostic (1.28e-1)" "unprognostic (5.35e-4)" "unprognostic (7.96e-2)" "unprognostic (7.64e-2)" "unprognostic (2.49e-1)" "unprognostic (8.38e-2)" 15.8 17.2 15.7 12.6 20.6 66.7 16.0 24.2 18.0 13.7 12.6 18.9 14.8 10.6 18.8 13.5 20.1 16.7 13.0 14.4 13.0 11.7 12.4 9.9 18.3 12.6 14.7 11.4 20.3 15.8 22.1 20.6 20.6 15.8 15.1 12.9 18.1 15.9 14.7 30.7 22.5 13.1 16.0 17.0 20.7 14.1 23.7 14.6 14.0 16.6 11.9 14.9 14.0 19.3 2.6 3.9 16.5 6.6 3.9 4.1 3.5 8.4 6.6 11.4 12.1 11.5 8.4 8.4 7.5 11.4 10.3 11.9 6.1 5.1 6.4 5.0 14.4 10.4 12.0 9.5 10.4 12.7 10.0 11.6 6.6 6.6 10.6 9.8 29.5 8.9 15.8 10.0 18.2 10.2 7.1 11.5 6.3 10.5 6.6 7.2 4.2 4.9 7.8 15.5 6.5 9.7 15.7 12.7 8.7 14.3 13.0 7.7 7.3 9.9 10.9 16.9 11.4 3.4 5.3 10.0 6.7 6.0 7.3 4.9 7.7 6.4 6.6 10.0 3.1 4.6 4.1 2.2 2.5 3.4 3.9 2.6 3.1 2.7 16.5 3.9 4.7 1.5 2.7 3.5 15.7 20.6 24.2 18.0 13.0 11.7 14.7 11.4 15.8 14.6 MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668771-110801620 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 50.0" "Group enriched" "Detected in some" 15 "LHCN-M2: 19.3;RH-30: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Not detected" "Not detected" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (5.39e-2)" "unprognostic (3.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (6.03e-5)" "unprognostic (4.58e-2)" "unprognostic (1.62e-1)" "unprognostic (9.67e-2)" "unprognostic (5.11e-2)" 7.5 0.3 0.6 5.8 0.7 0.0 0.2 0.1 0.2 0.3 6.8 0.0 0.0 2.3 0.2 4.0 3.8 0.1 2.1 3.2 0.9 0.7 0.2 0.5 4.2 0.9 0.2 0.1 0.3 0.3 0.0 0.2 0.6 0.3 1.9 5.3 0.0 0.4 0.0 50.0 0.3 5.0 3.0 0.3 0.2 2.6 5.9 0.0 0.0 0.3 1.4 3.9 3.6 2.9 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.4 0.2 0.0 19.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.2 0.9 0.7 0.2 0.1 0.3 0.0 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 15.8;blood: 32.3;brain: 28.3" "Cell line enriched" "Detected in some" 4 "HMC-1: 41.1" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enriched" "Detected in many" 5 "pons and medulla: 28.3" "Cell type enriched" "Detected in single" 127 "basophil: 32.3" "Lineage enriched" "Detected in single" 323 "granulocytes: 32.3" "Region enhanced" "Detected in some" "basal ganglia: 8.2" "Low region specificity" "Detected in all" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol 140000 "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: , HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 1.0 15.8 0.5 0.8 6.0 0.9 0.4 0.0 0.7 0.9 1.1 0.1 0.0 0.8 1.6 2.0 0.7 0.6 2.1 1.5 0.0 1.2 2.9 0.2 1.9 0.3 2.1 0.6 0.3 0.3 0.3 1.1 0.5 28.3 2.2 0.2 3.1 1.2 0.5 0.7 0.2 0.4 1.1 1.2 0.2 1.0 2.4 1.5 0.4 0.3 0.0 0.4 0.7 0.8 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.6 0.0 6.6 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 1.1 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.7 9.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 32.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.0 0.0 0.6 0.0 1.2 2.1 0.6 28.3 1.5 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027070 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Epilepsy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;thyroid gland: 63.4" "Cell line enhanced" "Detected in some" "AF22: 10.4;HaCaT: 3.7;RPTEC TERT1: 11.6;SH-SY5Y: 13.3" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346" Enhanced Approved Cytosol 13000000 Cytosol "CAB010346: AB_2155274, HPA007637: AB_1080385" "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 19.8 2.7 66.1 2.0 56.7 1.2 33.2 15.1 133.8 6.4 4.4 27.4 0.0 1.4 3.0 3.3 5.6 3.7 18.7 5.8 61.0 30.7 12.5 2.1 6.3 2.7 32.4 41.4 6.6 18.9 1.6 3.0 2.1 34.1 3.8 3.1 2.0 8.6 11.9 2.0 7.2 1.6 3.0 22.1 6.5 1.4 2.4 34.1 0.0 63.4 2.6 3.4 3.5 3.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.6 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.8 0.9 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 66.1 56.7 15.1 45.6 61.0 30.7 32.4 41.4 34.1 34.1 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8" "Cell line enriched" "Detected in some" 8 "U-138 MG: 47.4" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli" 11000000 Nucleoli "Nuclear membrane" "CAB009233: AB_632555, HPA027484: , HPA048065: " "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 20.8 7.4 22.0 2.5 28.1 1.5 6.2 30.4 41.8 7.0 4.0 8.4 1.3 2.0 12.4 6.7 3.4 9.5 3.9 5.5 22.0 11.1 5.1 2.0 5.7 3.1 11.2 18.7 5.1 2.9 1.6 7.9 2.8 14.7 6.8 4.7 8.0 11.5 8.7 1.9 2.9 2.5 7.7 13.7 4.1 3.0 13.8 13.7 0.0 2.5 0.7 4.3 7.1 4.8 0.7 0.4 1.3 0.5 0.5 0.8 0.0 0.0 5.9 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.9 0.0 0.5 0.0 0.0 0.0 1.4 0.0 0.1 1.2 0.5 0.4 0.3 0.1 0.2 0.4 0.3 0.3 0.1 0.7 0.4 0.4 1.3 0.5 0.1 0.4 0.8 0.0 22.0 28.1 30.4 28.9 22.0 11.1 11.2 18.7 14.7 13.7 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205126-17246005 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 48.7;lymphoid tissue: 60.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;EFO-21: 4.5;HaCaT: 2.8;LHCN-M2: 3.6;RPTEC TERT1: 4.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory region: 0.5" "Low region specificity" "Detected in some" HPA062294 Enhanced Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA062294: " "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavourable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.3 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.1 0.0 4.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.1 60.2 1.3 6.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.2 0.0 0.1 9.3 0.0 4.5 0.4 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119435 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.7;skeletal muscle: 126.4" "Cell line enhanced" "Detected in some" "A549: 6.8;RPTEC TERT1: 19.9;SK-BR-3: 30.4;T-47d: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.1;neutrophil: 37.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced "HPA047735: " "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 1.4 16.2 5.0 25.1 10.9 19.2 3.3 25.6 2.7 41.4 76.7 1.3 1.6 1.4 1.3 3.8 2.3 1.8 1.1 21.9 15.6 5.5 1.3 2.2 1.4 36.8 13.6 1.1 1.7 1.3 1.5 1.6 45.6 2.3 43.4 4.6 21.1 1.8 126.4 2.8 3.6 3.9 69.6 4.2 2.1 1.3 26.0 0.0 1.2 14.8 1.6 2.1 0.7 0.0 4.2 37.2 5.1 0.0 0.0 1.7 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 2.9 0.1 0.9 0.3 0.9 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.2 0.3 0.8 0.9 0.0 0.0 0.0 0.2 19.9 0.0 1.2 0.1 0.0 30.4 0.0 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.4 5.1 15.1 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 37.2 0.0 0.1 0.1 0.0 1.7 16.2 25.1 3.3 22.0 21.9 15.6 36.8 13.6 45.6 26.0 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.5;smooth muscle: 9.4;urinary bladder: 28.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.2;RT4: 15.8;T-47d: 11.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavourable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.1 0.0 0.0 3.2 10.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 6.4 0.0 2.3 0.0 9.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 28.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 13.2 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 15.8 0.0 0.0 0.0 2.3 0.1 11.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 48.2;bone marrow: 54.8;lymphoid tissue: 24.2" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HEL: 4.1;NB-4: 1.6;RPMI-8226: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "basophil: 17.0;classical monocyte: 18.6;eosinophil: 24.6;neutrophil: 48.2" "Group enriched" "Detected in many" 9 "granulocytes: 48.2;monocytes: 18.6" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced 12000 "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.2 0.2 0.3 0.5 0.2 54.8 0.2 0.1 0.8 0.2 0.2 0.5 0.0 0.2 0.2 0.1 0.4 0.9 0.4 9.8 0.6 0.1 0.3 1.2 9.7 5.2 1.8 0.0 0.9 0.3 0.1 0.6 4.1 0.6 0.1 0.2 0.9 0.5 0.1 0.2 0.2 0.2 0.4 0.2 24.2 0.3 1.0 0.3 2.6 0.6 0.2 0.2 0.4 7.5 0.4 3.6 48.2 18.6 1.1 1.2 8.1 0.2 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 4.1 0.1 0.4 0.0 0.4 0.5 0.0 0.5 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 1.6 0.2 0.2 0.2 0.0 4.8 0.0 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.1 0.0 0.2 0.5 0.1 17.0 18.6 24.6 0.1 1.4 0.0 0.2 0.1 0.2 3.6 0.4 0.7 1.2 48.2 1.1 0.4 1.6 0.1 8.1 0.3 0.2 0.1 0.8 0.6 0.1 1.8 0.0 0.6 0.3 PADI6 ENSG00000276747 "Peptidyl arginine deiminase 6" Q6TGC4 1 17372196-17401699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "blood: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in single" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (3.02e-2)" "unprognostic (6.56e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.8 0.0 1.9 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 0.1 0.0 0.0 0.2 1.1 3.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Cell line enhanced" "Detected in many" "A-431: 60.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavourable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavourable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 60.7 19.8 19.5 12.3 1.9 3.4 8.2 27.9 13.3 28.8 24.3 6.9 11.3 32.4 9.9 10.7 16.1 18.7 9.4 31.6 7.9 10.2 7.8 14.1 10.0 0.1 5.0 11.6 0.9 7.7 13.3 7.1 14.5 11.4 21.8 33.9 6.9 19.2 5.9 3.5 17.2 12.0 27.2 8.7 10.8 9.4 7.7 12.1 10.4 12.2 15.6 12.9 7.7 8.4 18.9 45.6 23.9 29.6 3.1 8.6 15.0 11.5 8.9 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229097-54298247 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 81.5" "Cell line enhanced" "Detected in some" "ASC diff: 81.0;ASC TERT1: 37.9;BJ hTERT+: 47.0;fHDF/TERT166: 32.7;HHSteC: 27.4;HSkMC: 68.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" 150000 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: " "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favourable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavourable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 35.0 12.4 12.6 16.1 7.6 0.9 17.2 2.4 20.1 33.2 19.1 9.2 6.4 9.6 27.6 14.6 21.9 22.5 16.2 15.3 8.9 7.4 22.8 8.4 24.1 26.9 9.2 4.0 81.5 6.8 1.6 2.1 25.1 7.2 18.6 15.2 19.2 8.5 8.3 11.9 7.0 17.4 19.7 8.8 51.6 13.6 19.0 9.3 0.5 11.3 12.8 4.3 35.9 24.6 0.9 0.4 2.5 0.4 0.3 0.8 0.3 0.0 0.0 0.2 0.1 81.0 37.9 0.1 4.2 47.0 0.0 0.1 11.2 0.0 0.1 0.1 32.7 0.1 3.2 0.0 0.0 0.4 0.1 0.1 0.1 0.2 27.4 0.0 0.0 68.9 0.0 5.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.3 0.1 6.6 0.0 0.1 0.0 0.1 0.0 0.1 14.8 0.5 16.2 0.0 0.0 0.0 0.1 0.4 0.0 0.3 2.5 0.4 0.2 0.5 0.2 0.2 0.6 0.8 0.4 0.0 0.9 0.7 0.4 2.3 0.3 0.3 0.4 0.2 0.3 12.6 7.6 2.4 7.3 8.9 7.4 9.2 4.0 7.2 9.3 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113837-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 169.0;ASC TERT1: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.9;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 8 "monocytes: 4.1;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" 35000000 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavourable (8.11e-4)" 61.8 10.4 8.3 11.0 9.1 0.5 66.1 4.6 10.4 73.1 15.7 6.7 6.9 5.1 44.3 17.3 21.7 26.1 51.7 24.2 8.2 3.9 17.0 4.6 28.9 21.5 7.9 8.1 46.5 7.5 10.4 7.7 46.4 7.7 24.2 6.3 22.9 11.2 19.3 29.8 20.3 11.2 29.8 5.0 19.6 9.2 21.5 6.7 1.4 21.4 16.0 7.3 23.6 35.1 0.4 0.1 0.0 4.1 0.0 2.9 0.6 0.0 0.0 1.0 0.0 169.0 58.5 0.3 5.9 24.5 4.1 7.0 0.6 0.0 0.0 0.7 16.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.4 24.0 0.0 0.0 26.3 0.0 5.7 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 2.2 2.8 0.3 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 2.9 0.6 0.0 0.4 0.1 0.8 0.1 0.1 0.0 1.3 0.0 0.0 4.1 0.0 0.0 0.6 8.3 9.1 4.6 10.4 8.2 3.9 7.9 8.1 7.7 6.7 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 21.5 6.0 14.3 8.7 13.2 9.7 12.4 8.4 14.1 15.1 9.3 12.3 6.2 7.2 16.1 8.7 6.6 7.5 12.2 18.5 12.3 7.5 6.6 4.9 20.5 7.5 13.8 8.8 9.8 5.8 7.6 4.2 19.5 9.8 8.4 10.2 13.7 7.0 9.5 8.8 8.4 9.1 14.8 10.1 41.8 6.7 11.5 15.9 2.7 8.3 9.0 5.7 10.0 12.2 0.9 0.6 1.1 0.6 5.5 1.4 0.4 2.5 3.8 9.0 2.1 17.0 18.4 3.1 14.0 9.7 7.4 7.5 3.0 2.3 2.0 2.5 20.1 1.2 7.2 2.2 8.5 2.0 3.7 3.6 5.7 1.8 6.2 2.1 1.9 14.1 2.2 14.4 2.4 20.8 4.7 2.0 7.9 1.0 1.2 2.3 4.1 1.0 2.5 5.4 1.4 2.2 4.6 2.0 2.4 5.4 1.1 9.4 0.8 1.5 25.4 15.9 7.6 6.6 5.9 3.1 4.4 2.8 2.7 5.1 8.5 0.4 0.6 1.1 0.7 0.2 1.4 0.9 0.2 0.2 0.3 0.8 0.3 0.3 0.6 5.5 0.2 0.6 0.2 0.4 14.3 13.2 8.4 14.1 12.3 7.5 13.8 8.8 9.8 15.9 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386498 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell line enhanced" "Detected in many" "A549: 28.1;NTERA-2: 18.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012066 Uncertain "HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favourable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 7.6 0.2 6.4 8.8 4.9 0.1 5.4 30.4 7.0 2.4 5.7 1.8 3.2 9.8 0.8 1.7 2.6 5.0 4.0 1.8 2.1 1.3 0.9 4.3 9.1 0.0 1.4 1.7 1.0 2.2 0.0 5.4 1.2 1.5 3.4 0.0 1.7 5.7 5.6 2.8 9.4 0.9 1.4 5.7 3.9 0.7 1.2 1.8 15.4 4.7 6.2 1.5 0.2 3.1 4.6 2.2 1.6 1.3 3.9 0.4 3.4 28.1 3.2 0.4 0.0 0.2 8.0 7.1 1.5 2.8 1.2 13.9 8.2 5.6 4.9 3.4 12.2 0.5 8.6 0.6 0.2 0.9 0.0 3.4 7.8 3.1 0.8 8.9 0.7 5.6 0.4 1.3 5.8 0.0 0.0 2.1 4.7 0.7 2.6 18.2 7.2 3.6 3.4 1.3 4.1 9.8 1.6 1.0 2.7 7.9 2.8 6.1 3.5 7.7 0.3 7.5 0.0 1.7 0.4 0.6 7.7 1.8 1.9 4.2 0.0 0.5 2.2 1.2 0.1 0.9 3.1 1.5 0.4 0.7 2.6 3.9 3.2 0.0 1.3 1.6 4.6 0.2 0.4 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" 32000 "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavourable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 22.6 20.4 36.0 14.4 42.3 3.1 19.3 20.5 40.8 24.9 17.9 55.7 23.5 14.5 20.2 29.9 14.6 18.7 18.4 20.0 43.5 23.9 22.3 17.0 21.5 13.0 41.4 31.4 19.4 18.2 33.1 13.0 42.1 30.0 19.2 20.7 11.0 21.9 25.5 17.9 13.5 16.3 21.9 38.0 12.2 17.5 21.2 46.1 2.8 22.5 10.2 14.0 22.2 17.8 8.6 7.2 1.8 3.9 5.2 5.7 4.1 14.6 23.4 32.5 11.7 13.7 14.7 21.0 14.5 20.2 13.6 13.4 10.2 12.2 8.9 33.0 18.6 17.4 19.1 33.3 20.6 0.1 8.9 19.7 12.9 14.0 18.7 0.0 9.4 10.0 16.4 17.0 24.0 40.1 19.8 0.2 18.2 25.5 0.2 0.2 12.6 26.2 13.1 17.8 0.4 28.7 33.5 12.9 16.1 22.7 7.3 14.7 17.2 0.3 24.2 13.4 25.3 15.8 16.3 0.0 0.1 0.9 17.4 0.1 18.1 1.8 3.9 0.0 0.3 1.6 0.0 6.8 0.8 0.1 5.3 8.6 5.7 2.0 1.7 5.2 0.9 7.2 0.2 4.1 36.0 42.3 20.5 40.8 43.5 23.9 41.4 31.4 30.0 46.1 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7;brain: 65.2" "Cell line enhanced" "Detected in many" "Daudi: 37.0;REH: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 202.9;basal ganglia: 236.9;cerebral cortex: 189.7;hippocampal formation: 443.3;olfactory region: 185.5" "Low region specificity" "Detected in many" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" 84000 "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favourable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favourable (5.11e-4)" "unprognostic (3.33e-3)" 7.2 4.7 20.4 24.3 30.0 46.7 4.9 65.2 48.3 5.4 14.5 7.8 5.0 16.6 4.3 4.7 7.9 6.8 6.4 4.7 30.5 7.0 6.8 5.0 11.5 35.6 4.3 25.4 2.4 5.4 5.2 5.3 4.1 3.9 10.1 11.9 8.3 12.6 6.7 2.2 15.1 18.4 5.5 4.8 32.0 10.8 4.3 3.7 37.8 5.6 2.9 35.4 13.0 6.0 26.9 18.7 24.0 25.8 14.7 19.0 21.5 10.9 3.0 0.8 0.9 23.5 1.7 6.4 0.8 0.5 0.6 0.8 2.9 6.3 37.0 1.2 1.7 10.1 0.3 9.2 0.3 2.5 0.2 7.6 2.9 0.5 4.8 8.2 13.8 12.7 13.8 0.8 5.3 0.3 8.9 25.7 0.6 1.1 14.0 16.5 0.6 0.8 41.0 0.2 25.3 2.6 8.6 5.8 1.0 3.9 2.7 1.4 3.3 21.2 5.2 0.4 0.8 0.7 0.3 20.7 8.9 20.0 1.6 17.8 0.7 22.3 23.7 18.0 19.0 22.4 12.5 25.5 9.6 13.3 18.7 26.9 12.1 14.2 24.0 14.7 25.8 6.2 9.5 21.5 20.4 30.0 65.2 48.3 30.5 7.0 4.3 25.4 3.9 3.7 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537370 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.0;intestine: 24.2;skin 1: 24.2" "Cell line enhanced" "Detected in some" "A-431: 11.3;CAPAN-2: 21.8;HaCaT: 17.7;hTCEpi: 24.0;RT4: 13.8;T-47d: 13.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavourable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.7 0.0 0.4 5.3 0.4 0.0 1.7 0.4 0.4 7.6 18.1 0.5 0.8 13.6 0.6 0.5 44.0 0.0 11.7 0.4 0.4 0.0 0.8 1.7 1.1 0.4 0.4 0.4 0.4 1.4 0.0 0.4 0.6 0.4 2.2 7.4 0.4 7.6 0.4 0.4 24.2 24.2 0.9 0.4 0.4 12.5 0.4 0.4 0.4 0.4 18.9 17.2 6.5 15.0 1.3 4.5 1.2 2.4 0.3 1.9 0.9 11.3 1.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 21.8 0.0 3.9 0.0 17.7 0.0 0.0 0.0 2.8 0.2 0.0 4.5 0.0 0.0 0.0 3.6 0.0 24.0 0.0 0.1 0.0 0.1 1.3 0.1 6.3 0.0 0.1 0.1 8.2 0.0 0.6 0.2 0.0 13.8 0.2 1.2 1.3 4.3 0.0 13.3 0.8 0.1 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.2 0.2 0.6 1.2 2.4 0.4 0.5 1.7 1.9 1.2 0.4 0.1 4.5 1.3 0.4 0.6 1.2 0.3 1.3 0.3 0.5 0.9 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076268-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 13.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" 10000000 "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 5.4 1.8 1.4 3.5 3.4 0.8 12.2 3.5 4.9 30.9 4.8 3.4 8.9 2.1 37.7 36.9 11.7 14.3 14.5 3.5 2.2 3.9 10.1 0.8 18.7 4.3 1.3 2.7 42.6 16.3 9.0 9.0 20.9 4.2 18.2 3.3 13.9 15.0 10.9 0.4 13.6 3.4 16.4 3.2 12.4 4.6 14.9 1.4 28.7 19.3 8.1 6.2 9.5 17.6 0.0 13.8 0.3 0.0 0.7 1.5 0.8 2.1 0.6 21.1 35.1 22.7 23.3 30.0 22.6 36.5 19.8 25.4 19.0 7.6 0.0 17.9 26.3 24.5 9.4 21.5 12.6 0.1 11.7 2.0 4.3 25.5 34.5 0.0 0.1 33.3 19.5 26.1 8.3 2.5 1.3 0.0 9.0 1.6 7.6 3.0 9.8 1.7 7.7 30.0 0.0 15.3 10.5 12.1 23.0 3.6 0.3 11.7 12.9 4.6 1.6 21.2 13.4 0.1 12.2 0.1 0.2 0.7 4.9 0.0 3.5 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 1.5 0.2 0.7 0.0 13.8 0.0 0.8 1.4 3.4 3.5 4.9 2.2 3.9 1.3 2.7 4.2 1.4 PTP4A1 "PRL-1, PRL1, PTPCAAX1" ENSG00000112245 "Protein tyrosine phosphatase type IVA, member 1" Q93096 6 63521748-63583587 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 135.1;skeletal muscle: 111.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Approved "HPA003281: AB_1855903" "unprognostic (8.63e-2)" "prognostic unfavourable (5.53e-4)" "unprognostic (9.05e-2)" "unprognostic (7.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.23e-2)" "unprognostic (1.07e-2)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (1.11e-2)" 13.9 42.3 11.3 10.5 14.0 54.3 10.8 7.1 17.0 17.5 30.2 18.9 8.0 17.9 13.1 13.5 16.1 12.3 16.7 10.0 12.0 14.8 14.2 135.1 25.0 9.0 16.1 13.8 24.1 87.4 5.0 12.8 19.8 16.3 17.7 31.2 13.6 20.1 10.0 111.2 17.2 18.3 35.7 24.2 7.1 15.5 19.8 13.3 6.4 11.4 19.9 9.3 31.0 12.6 14.6 18.2 46.9 20.6 15.8 20.1 14.4 18.9 23.6 29.7 28.7 20.3 18.9 59.5 33.4 22.3 12.2 17.0 19.8 11.2 16.2 14.5 19.7 9.4 20.2 42.0 19.6 17.4 13.6 10.1 65.9 89.9 40.2 31.0 16.5 22.9 81.5 26.3 70.5 18.8 23.1 31.5 33.8 25.7 14.8 13.9 12.3 12.8 19.9 12.3 12.8 27.2 22.5 11.2 20.6 73.0 16.0 32.9 15.4 27.6 18.7 30.7 33.7 24.2 32.9 26.3 22.5 29.9 16.4 16.6 36.0 34.6 19.8 15.2 13.7 20.6 20.1 14.6 15.0 14.6 18.2 12.4 14.8 14.2 46.9 15.8 14.2 9.1 18.1 14.4 11.3 14.0 7.1 17.0 12.0 14.8 16.1 13.8 16.3 13.3 PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase type IVA, member 2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain 440000 "CAB011204: AB_532271, HPA003281: AB_1855903" "unprognostic (2.67e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-3)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (6.20e-2)" "prognostic unfavourable (2.62e-5)" "unprognostic (6.90e-2)" "unprognostic (4.63e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "prognostic unfavourable (5.10e-11)" "unprognostic (1.16e-2)" "unprognostic (3.81e-1)" "unprognostic (2.89e-1)" "prognostic favourable (2.72e-5)" 51.6 22.4 41.1 39.6 57.3 74.6 48.8 12.0 34.6 26.3 37.1 68.9 24.9 31.9 23.4 20.8 25.3 23.9 31.6 64.8 50.6 31.4 26.7 36.3 34.6 44.0 56.3 29.5 34.6 28.5 17.1 19.2 25.8 40.9 28.6 36.9 21.1 28.0 27.5 82.8 16.5 29.1 32.7 58.5 40.9 31.3 44.6 48.7 110.5 48.0 20.0 47.2 49.0 40.3 14.7 14.8 50.0 44.6 18.2 29.0 18.2 41.5 24.2 23.8 44.3 47.7 51.1 16.2 40.8 57.0 33.5 34.9 21.2 60.3 73.9 32.2 55.4 16.9 24.2 23.7 62.3 66.4 13.8 51.3 43.0 22.1 51.2 41.6 52.0 46.9 19.8 47.3 46.7 34.0 65.9 30.3 43.0 20.2 133.2 20.4 31.8 35.4 23.2 39.9 30.7 22.4 76.9 23.3 16.8 43.5 28.4 46.2 80.9 23.1 35.1 39.5 33.4 58.9 45.0 31.6 49.2 37.7 38.3 34.2 38.3 50.0 17.2 27.4 25.4 32.6 20.3 14.7 22.6 29.0 14.8 11.3 14.5 24.9 18.0 18.2 44.6 10.7 17.8 18.2 41.1 57.3 12.0 34.6 50.6 31.4 56.3 29.5 40.9 48.7 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase type IVA, member 3" O75365 8 141391993-141432454 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 166.4" "Cell line enhanced" "Detected in some" "HDLM-2: 68.7;Karpas-707: 20.9;RPMI-8226: 21.5;U-266/84: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 30.3;non-classical monocyte: 27.8" "Group enriched" "Detected in many" 7 "granulocytes: 30.3;monocytes: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavourable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 5.9 2.4 2.8 3.9 6.5 1.7 4.1 3.9 10.9 5.5 6.2 2.6 2.5 3.4 7.6 5.4 5.5 6.1 3.0 48.0 2.7 3.0 5.1 1.7 5.5 7.9 2.8 5.0 4.8 13.6 2.4 22.0 4.1 4.6 7.2 2.0 15.7 8.2 3.8 166.4 3.4 3.3 7.6 1.5 5.6 9.9 3.5 0.6 1.7 3.3 15.9 5.1 5.5 3.3 2.8 4.3 30.3 27.8 0.8 3.5 2.5 0.1 0.4 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.0 0.0 6.4 0.1 0.0 0.1 0.0 0.0 68.7 0.5 4.9 0.0 1.0 0.5 0.0 0.2 0.0 0.2 0.0 0.0 0.1 2.7 20.9 0.0 5.2 0.5 0.1 1.3 0.3 11.8 0.0 21.5 0.0 0.1 8.8 2.1 0.4 0.0 1.8 1.0 0.3 0.1 0.0 1.2 0.0 0.0 6.5 22.8 0.2 0.0 2.0 0.2 0.4 1.6 6.6 1.6 14.8 1.1 2.8 3.5 1.6 1.2 0.8 3.4 1.9 30.3 0.8 27.8 4.3 2.5 2.5 2.8 6.5 3.9 10.9 2.7 3.0 2.8 5.0 4.6 0.6 PTPDC1 "FLJ37312, PTP9Q22" ENSG00000158079 "Protein tyrosine phosphatase domain containing 1" A2A3K4 9 94030794-94109856 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 32.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.0" "Group enriched" "Detected in many" 5 "B-cells: 1.1;T-cells: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016747, HPA026832" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA016747: AB_1855908, HPA026832: AB_10602917" "unprognostic (3.99e-2)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.91e-2)" "unprognostic (1.94e-1)" "unprognostic (3.64e-2)" "unprognostic (1.90e-3)" "unprognostic (4.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.56e-1)" "unprognostic (3.49e-2)" "unprognostic (3.55e-2)" "unprognostic (2.48e-2)" "unprognostic (2.45e-2)" "unprognostic (2.17e-1)" "unprognostic (1.28e-1)" "unprognostic (2.61e-2)" 7.0 12.0 7.6 4.4 32.3 1.5 6.4 4.7 16.4 4.7 4.9 25.3 1.4 3.1 6.2 4.9 4.4 4.4 4.7 10.0 12.1 6.9 5.1 2.4 6.8 3.7 13.9 8.9 6.3 12.2 6.8 8.9 3.7 19.9 5.6 5.9 4.1 4.3 4.4 7.0 6.2 3.6 8.3 20.5 3.0 7.1 15.0 13.0 1.6 5.1 1.3 3.9 4.9 3.6 1.1 0.3 0.0 0.2 0.0 2.0 0.1 6.2 2.7 4.9 6.3 6.1 8.5 6.6 4.5 3.2 4.7 3.9 2.6 5.2 5.2 3.1 3.5 4.9 5.0 2.9 4.6 7.0 1.4 1.2 7.2 2.8 8.0 1.4 4.0 8.4 10.5 7.0 9.8 4.9 3.0 0.0 8.7 3.3 5.2 2.2 3.5 5.1 5.7 9.8 0.0 2.6 1.5 4.3 5.5 6.2 5.9 9.7 3.2 2.5 6.9 6.2 3.8 9.5 5.5 7.7 8.4 0.7 4.6 2.6 8.6 0.0 0.2 0.0 0.1 0.0 0.1 0.4 1.1 0.0 0.3 1.1 2.0 0.7 0.0 0.0 0.2 0.2 0.0 0.1 7.6 32.3 4.7 16.4 12.1 6.9 13.9 8.9 19.9 13.0 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040348, HPA043932" Approved Supported Mitochondria Mitochondria "HPA040348: , HPA043932: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.0 12.5 1.5 10.0 11.6 8.9 4.3 13.0 12.3 13.0 12.4 20.7 11.8 15.9 14.4 9.7 18.9 10.3 13.5 13.9 19.4 31.0 7.3 25.6 26.0 17.0 14.2 9.7 8.8 15.3 6.1 18.7 9.2 18.6 12.2 9.5 41.6 12.1 18.3 9.3 23.2 22.2 8.4 13.5 15.6 14.1 9.3 11.4 19.7 7.2 11.7 33.5 15.3 9.9 9.7 14.8 15.6 19.5 18.6 12.4 10.8 7.6 12.3 5.8 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase, non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" 11000 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 22.1 22.2 12.1 31.9 16.0 35.3 17.9 12.9 16.6 18.2 17.8 18.8 14.2 10.5 20.0 16.6 23.2 17.1 18.0 20.5 15.8 9.0 43.8 16.7 42.7 36.1 14.1 14.1 21.8 12.2 31.2 18.8 28.3 18.7 20.0 14.8 21.0 16.3 15.0 41.0 18.6 21.9 16.9 15.8 45.3 17.5 23.5 13.3 26.9 15.7 13.9 42.8 20.0 18.4 15.9 9.4 18.8 16.4 3.9 10.7 6.4 20.7 10.5 12.7 8.7 8.3 11.5 18.0 14.0 13.3 41.1 15.0 30.8 43.8 10.3 24.9 12.9 18.5 10.1 40.1 26.2 15.3 9.0 14.6 10.2 16.2 16.6 15.1 20.0 13.4 28.2 18.5 22.8 23.6 25.3 9.5 22.3 11.5 16.2 12.0 6.7 14.4 14.4 14.8 9.8 23.7 15.6 10.2 11.7 20.1 25.5 22.6 16.5 16.2 35.0 35.9 14.4 16.1 17.3 10.4 8.4 12.6 22.5 10.3 13.2 12.0 5.6 18.8 10.7 9.5 7.9 15.9 9.0 8.2 5.5 13.7 7.7 8.3 12.2 3.9 16.4 9.4 7.1 6.4 12.1 16.0 12.9 16.6 15.8 9.0 14.1 14.1 18.7 13.3 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" 160000 Nucleoli "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 34.8 33.3 24.3 23.0 35.4 34.6 28.8 42.4 46.3 33.4 25.2 33.1 13.5 36.9 22.1 39.2 20.9 31.2 37.6 55.7 28.0 25.7 53.7 31.0 18.1 35.4 43.0 34.3 28.0 37.9 35.9 51.1 27.6 40.7 13.0 32.2 25.2 30.2 20.9 29.4 21.8 31.1 35.9 21.2 30.8 39.2 16.9 20.8 40.8 31.3 26.0 36.0 29.9 33.6 39.4 35.3 23.4 37.1 25.2 41.5 36.9 32.7 30.2 36.8 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase, non-receptor type 12" Q05209 7 77537275-77640071 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" 1100000 "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavourable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavourable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavourable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 29.6 15.1 14.3 20.5 19.6 29.7 25.1 15.7 22.7 20.0 28.9 8.1 13.8 8.8 20.7 9.6 22.0 18.1 19.8 45.6 17.3 12.6 16.9 14.8 34.7 17.4 15.3 13.4 19.0 10.7 12.4 19.8 36.0 18.6 14.1 13.8 9.9 12.8 17.1 17.6 17.6 14.6 23.0 24.0 25.0 14.4 13.9 17.7 9.7 16.7 11.9 12.9 23.2 61.2 2.5 3.9 9.9 4.9 12.8 3.8 2.8 17.5 10.8 25.7 13.1 18.1 18.9 13.8 18.4 23.4 14.5 20.7 5.3 27.6 2.1 5.9 21.5 12.6 8.6 18.4 29.3 5.1 4.8 11.0 10.9 21.7 17.7 6.2 7.4 15.4 20.6 31.5 40.8 30.6 13.2 3.1 46.2 12.0 0.8 17.4 20.7 12.4 3.7 20.6 1.1 24.9 9.5 3.2 17.1 22.6 20.7 17.9 10.0 23.0 22.2 31.4 19.0 11.4 34.6 3.2 1.7 5.4 18.5 16.3 54.4 3.7 4.2 6.6 3.6 2.9 1.4 2.5 1.2 2.7 3.9 1.1 0.6 3.8 9.9 12.8 4.9 0.3 1.5 2.8 14.3 19.6 15.7 22.7 17.3 12.6 15.3 13.4 18.6 17.7 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase, non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 7 "monocytes: 4.9;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 10.3 5.9 10.8 2.7 16.9 0.7 9.9 5.7 11.6 15.9 4.1 13.0 7.6 1.2 10.8 21.2 18.7 11.4 6.5 5.3 10.4 5.7 22.1 1.6 18.0 4.3 16.9 7.9 24.1 4.3 26.6 38.3 3.0 14.2 12.0 2.4 39.0 5.9 9.4 1.0 43.0 2.3 8.7 10.3 3.5 3.6 12.2 17.6 1.9 16.9 12.4 11.8 15.7 17.6 0.0 0.5 0.1 4.9 0.1 2.3 0.1 5.0 2.5 44.4 4.3 18.8 16.4 0.0 9.3 19.1 3.5 4.5 0.0 2.5 0.0 2.0 10.3 16.7 7.7 14.1 6.9 0.1 5.7 4.2 5.5 0.0 2.3 7.4 0.0 10.5 4.5 2.6 8.6 0.0 0.0 7.2 0.0 2.2 0.6 2.7 10.1 1.9 1.5 0.0 0.0 13.5 21.2 2.6 3.7 2.8 6.2 5.1 3.6 0.2 0.0 3.4 2.7 0.0 1.2 7.6 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.2 3.0 2.3 0.0 2.2 0.3 0.5 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.1 0.1 10.8 16.9 5.7 11.6 10.4 5.7 16.9 7.9 14.2 17.6 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase, non-receptor type 14" Q15678 1 214348696-214552449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: " "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 13.6 10.0 3.0 6.5 2.4 0.2 15.0 0.8 3.7 13.6 8.5 2.6 11.0 1.0 15.4 8.0 8.6 9.2 9.7 7.0 3.5 1.9 11.2 2.0 12.2 6.6 2.4 1.3 11.8 5.0 6.3 4.0 13.2 4.9 10.6 2.9 7.2 9.2 23.4 21.6 18.8 3.5 9.4 4.3 5.3 5.7 8.3 2.4 1.4 8.1 6.9 3.7 12.4 17.7 1.0 0.5 1.9 0.4 1.0 0.6 0.1 8.7 3.9 3.2 4.6 5.6 9.5 9.4 9.9 9.3 7.6 6.4 7.9 4.6 0.0 11.1 23.1 7.8 4.3 11.1 13.1 0.1 3.3 0.8 11.1 1.4 10.1 0.1 0.4 7.1 11.6 13.2 21.3 14.7 0.0 0.1 18.4 0.9 0.1 0.1 7.0 4.2 0.1 16.0 0.0 13.7 4.4 0.0 0.7 12.3 8.1 5.0 8.0 0.3 26.2 17.9 7.0 6.4 14.1 0.5 0.0 0.0 9.6 0.1 14.9 1.3 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.4 0.1 1.0 0.5 0.6 1.9 1.0 0.4 0.5 0.6 0.1 3.0 2.4 0.8 3.7 3.5 1.9 2.4 1.3 4.9 2.4 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase, non-receptor type 18" Q99952 2 130356007-130375409 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" 550000 "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: " "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 12.8 7.1 11.0 16.7 13.5 18.9 22.3 26.8 13.7 15.3 22.8 6.6 25.7 16.6 9.3 11.0 11.3 13.3 21.3 7.5 9.8 8.5 13.9 19.2 16.9 29.2 8.4 9.5 7.8 28.9 6.4 11.0 9.4 6.9 17.8 19.3 7.9 18.5 24.0 11.0 6.9 28.8 10.5 9.1 37.7 16.0 3.3 9.1 1.6 13.0 7.1 35.5 11.0 10.7 7.6 7.4 6.2 17.1 2.8 6.6 10.2 5.8 3.9 1.5 7.9 9.8 6.8 16.3 3.0 2.7 3.9 4.3 7.8 8.9 21.8 3.0 7.2 6.7 6.9 6.7 3.8 9.9 3.8 7.9 4.7 9.1 5.1 7.7 21.4 8.0 5.5 4.2 5.9 7.3 7.3 16.6 7.4 11.3 1.4 13.3 1.6 4.2 13.3 4.5 29.5 7.7 3.6 10.1 2.6 5.3 18.9 8.6 6.5 11.3 6.8 5.5 6.3 3.0 2.7 2.6 0.7 20.9 8.5 7.0 6.0 6.2 7.8 6.1 6.6 10.8 4.1 7.6 4.4 6.3 6.7 4.5 2.7 5.4 4.9 2.8 17.1 7.4 5.6 10.2 11.0 13.5 26.8 13.7 9.8 8.5 8.4 9.5 6.9 9.1 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase, non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favourable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 16.7 12.5 12.6 27.0 14.3 33.7 19.9 32.6 19.2 14.7 15.0 7.8 17.8 12.9 12.2 14.9 17.0 13.7 15.7 12.8 13.1 6.8 13.6 20.5 21.6 30.3 15.3 10.3 22.1 28.2 10.4 27.2 13.3 13.8 14.4 17.1 7.9 26.3 16.0 13.1 16.0 15.3 11.8 24.7 24.2 13.1 9.4 15.9 61.3 14.7 11.7 28.9 16.5 15.8 29.1 32.8 19.9 28.0 31.7 29.2 19.6 13.0 7.9 9.3 3.1 10.6 19.2 9.0 8.7 19.4 18.7 16.8 17.2 18.9 20.5 14.7 9.0 7.8 15.1 23.9 24.7 7.9 9.1 14.5 6.9 17.9 14.7 33.9 13.8 16.1 22.7 17.0 33.8 9.5 14.0 27.9 15.0 14.9 33.8 28.0 11.1 9.3 11.4 14.6 23.2 15.7 20.9 16.7 8.7 17.7 10.4 15.1 8.7 19.5 7.2 23.8 23.0 17.7 18.8 8.9 8.9 29.6 11.2 18.7 9.9 11.5 28.0 19.9 21.0 24.6 28.2 29.1 24.8 23.1 32.8 20.3 18.3 20.0 10.2 31.7 22.8 28.0 29.2 19.6 12.6 14.3 32.6 19.2 13.1 6.8 15.3 10.3 13.8 15.9 PTPN21 "PTPD1, PTPRL10" ENSG00000070778 "Protein tyrosine phosphatase, non-receptor type 21" Q16825 14 88465778-88554733 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB011468, HPA073999" Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centriolar satellite" "CAB011468: AB_442979, HPA073999: " "unprognostic (2.18e-1)" "unprognostic (4.21e-2)" "unprognostic (7.60e-2)" "unprognostic (3.09e-2)" "unprognostic (4.60e-2)" "unprognostic (5.71e-2)" "unprognostic (6.55e-2)" "unprognostic (5.19e-3)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-3)" "unprognostic (3.04e-3)" "prognostic favourable (3.16e-9)" "unprognostic (6.52e-2)" "unprognostic (2.69e-1)" "unprognostic (2.56e-1)" "unprognostic (7.67e-2)" 10.5 4.7 5.3 8.6 7.3 0.0 13.2 4.4 5.8 10.7 8.7 10.7 7.4 4.9 10.6 10.7 8.9 8.3 12.7 17.4 7.4 4.2 8.1 6.0 15.3 1.6 6.6 4.2 15.8 7.8 10.6 3.9 15.6 6.4 11.9 6.5 12.6 6.5 10.5 8.8 24.2 10.5 15.7 7.3 3.7 7.4 15.2 6.5 0.8 16.0 8.4 3.1 12.0 26.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 3.5 2.9 7.6 2.9 8.1 7.0 7.8 9.6 7.4 5.7 7.9 5.1 6.5 0.0 2.3 12.2 3.4 1.1 3.4 8.4 0.2 1.7 0.0 3.1 2.1 9.0 0.0 0.1 4.7 6.7 4.8 5.7 4.6 1.1 0.1 14.6 2.9 0.0 0.1 2.2 5.6 0.0 22.7 0.0 4.9 2.6 0.5 8.8 5.5 13.8 3.2 6.8 1.4 9.0 10.6 8.4 4.3 6.5 0.3 1.1 0.0 3.9 0.1 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.3 4.4 5.8 7.4 4.2 6.6 4.2 6.4 6.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase, non-receptor type 22" Q9Y2R2 1 113813811-113871759 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease mutation, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;lymphoid tissue: 46.0" "Cell line enhanced" "Detected in some" "Daudi: 32.9;HL-60: 13.0;U-266/70: 14.2;U-698: 17.6;U-937: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in single" 10 "cerebellum: 5.9" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 4.2 1.4 0.5 17.1 0.8 23.6 1.9 1.0 0.5 2.4 3.3 0.3 1.0 4.1 2.0 2.2 2.0 1.7 3.2 2.5 0.6 0.7 3.4 1.8 9.0 14.9 0.7 0.4 1.5 2.4 0.0 0.9 0.9 1.0 1.7 2.8 1.3 2.7 3.0 0.6 1.0 9.9 0.9 2.1 19.0 3.1 1.1 0.4 46.0 1.5 2.4 12.8 4.8 1.7 7.2 6.2 17.2 3.5 7.5 14.9 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.3 0.0 0.2 32.9 0.0 0.1 0.0 0.0 0.0 0.2 3.1 0.0 4.6 0.0 0.0 0.1 13.0 10.3 2.9 0.0 1.4 0.1 5.1 0.0 7.5 5.0 0.1 9.2 7.4 0.0 0.0 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 2.3 7.8 0.1 0.1 0.2 14.2 3.0 17.6 5.4 13.4 0.0 10.2 3.5 17.2 12.8 0.9 14.9 7.2 6.5 10.1 6.2 4.7 3.9 9.4 1.7 7.5 0.4 3.7 10.0 4.6 0.5 0.8 1.0 0.5 0.6 0.7 0.7 0.4 1.0 0.4 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase, non-receptor type 23" Q9H3S7 3 47381011-47413441 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favourable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 15.9 18.5 23.1 17.4 22.3 19.2 21.6 22.8 25.0 18.1 12.5 21.4 14.6 20.7 20.0 15.1 17.2 17.2 12.8 13.2 17.9 11.7 16.4 13.0 16.8 17.8 24.6 23.7 23.4 19.4 53.4 29.9 17.1 20.5 16.9 10.4 15.2 20.8 19.0 25.7 25.9 16.0 16.0 20.3 19.2 17.9 17.8 22.7 9.7 24.8 9.7 11.1 17.7 18.1 1.4 1.1 3.7 1.2 0.9 1.5 0.8 13.1 18.7 10.4 13.5 13.6 10.5 10.0 11.9 11.9 11.2 9.5 15.8 13.0 9.4 11.0 13.5 11.8 9.0 13.0 5.4 8.6 9.6 12.8 13.7 14.6 15.0 7.5 17.5 14.0 13.3 14.5 14.9 13.7 9.6 12.9 11.9 18.3 7.1 6.3 11.1 13.1 4.4 5.1 11.2 8.4 25.3 5.6 13.1 10.5 22.5 8.7 12.8 7.3 13.8 17.2 14.5 23.8 16.9 18.4 12.1 5.4 18.6 7.1 12.1 3.7 1.2 0.0 0.8 0.5 0.6 1.4 0.6 1.3 0.4 0.7 0.6 0.8 1.4 0.9 0.5 1.1 1.5 0.8 23.1 22.3 22.8 25.0 17.9 11.7 24.6 23.7 20.5 22.7 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase, non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.1" "Cell line enhanced" "Detected in many" "HaCaT: 15.4;RPTEC TERT1: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved "HPA038343: AB_10671741, HPA046728: " "prognostic unfavourable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favourable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 2.7 1.9 3.4 4.8 5.0 0.0 4.8 2.1 11.1 4.4 9.4 2.0 10.7 7.6 3.2 13.4 10.3 6.4 6.3 12.1 3.1 2.8 28.8 21.1 4.9 0.5 1.2 3.9 1.5 17.0 10.6 4.9 14.5 4.5 4.7 6.5 3.8 13.1 13.6 38.1 18.8 18.8 0.8 0.9 0.9 5.9 2.1 0.0 1.1 9.4 7.2 9.5 4.1 5.5 0.6 0.3 2.8 0.6 0.3 0.3 0.1 6.4 8.0 0.3 2.1 0.0 0.0 12.7 1.4 0.0 1.7 1.9 4.2 10.5 0.0 1.5 0.1 15.4 2.2 9.0 1.8 3.5 4.9 0.0 3.8 4.3 0.0 0.0 0.1 0.1 9.7 2.2 4.7 0.0 0.0 0.1 0.1 8.1 11.0 1.9 1.0 6.0 0.0 2.6 0.1 20.7 12.4 5.2 1.1 3.5 13.1 0.0 7.5 1.0 0.0 0.6 5.1 0.8 0.0 6.3 10.3 0.0 6.8 0.0 4.6 0.4 0.6 0.8 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.6 0.3 0.3 2.8 0.3 0.6 0.3 0.1 0.1 3.4 5.0 2.1 11.1 3.1 2.8 1.2 3.9 4.5 0.0 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase, non-receptor type 4" P29074 2 119759631-119983818 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 16 "NK-cells: 12.2;T-cells: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favourable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 6.8 6.9 10.0 5.9 12.2 7.3 7.2 37.4 16.9 9.6 5.5 7.2 5.2 8.1 7.2 6.6 6.9 8.9 6.3 8.9 10.2 8.4 12.0 6.6 8.0 7.9 7.3 13.1 8.9 6.3 11.6 16.3 4.1 8.3 6.2 4.0 7.1 7.9 6.6 11.2 5.8 5.5 4.7 7.3 9.2 8.9 7.7 6.5 18.9 22.5 6.8 6.5 5.3 5.8 0.5 0.3 0.9 0.4 12.2 19.3 4.7 7.3 4.3 5.7 7.6 5.1 5.3 9.7 3.3 9.4 1.9 5.2 6.4 11.4 5.3 8.0 3.7 6.5 4.4 5.2 5.1 12.3 3.7 3.6 4.1 6.1 3.4 3.7 2.7 4.8 9.8 8.8 4.0 8.3 6.2 5.4 5.0 5.6 5.1 4.3 7.5 7.1 3.5 9.8 7.4 6.9 10.0 7.4 9.2 4.6 5.9 3.8 2.8 2.4 10.4 0.2 6.5 2.2 4.0 9.3 13.0 6.7 4.9 0.2 3.1 0.2 0.2 0.9 19.3 0.3 15.6 0.5 9.6 15.1 0.3 0.5 3.2 11.0 0.7 12.2 0.4 0.3 5.6 4.7 10.0 12.2 37.4 16.9 10.2 8.4 7.3 13.1 8.3 6.5 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase, non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 70.0" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HMC-1: 3.6;NTERA-2: 5.7" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 70.0" "Cell type enriched" "Detected in single" 9 "basophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: " "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 2.5 1.6 16.3 1.1 70.0 1.1 1.2 0.9 47.5 1.5 1.1 0.4 0.0 1.1 1.2 1.0 1.3 1.7 1.4 4.3 9.1 8.6 1.1 0.9 2.7 1.1 3.5 16.0 2.5 1.2 1.5 0.5 0.9 6.1 1.6 1.4 0.0 1.3 1.7 1.8 1.0 1.4 1.4 2.1 1.3 1.3 3.4 9.3 0.0 1.2 0.0 1.0 1.5 0.3 0.1 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 5.7 0.3 0.0 0.1 0.1 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 70.0 0.9 25.1 9.1 8.6 3.5 16.0 6.1 9.3 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase, non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 107.1;lymphoid tissue: 69.0" "Cell line enhanced" "Detected in many" "HEL: 28.1;HL-60: 24.9;HMC-1: 110.1;THP-1: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli 7400000 Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favourable (1.87e-4)" "prognostic unfavourable (5.42e-4)" "prognostic favourable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favourable (2.64e-8)" 6.6 8.8 2.4 42.9 4.4 27.7 4.6 1.2 2.7 2.8 7.0 5.1 4.7 7.5 3.7 8.8 7.0 5.0 9.8 2.9 3.1 2.3 7.0 6.8 25.4 58.1 5.2 1.8 2.3 6.7 2.7 5.6 7.7 3.9 5.6 5.2 3.6 10.6 7.0 1.3 6.1 21.0 2.6 4.9 69.0 6.6 1.5 3.3 31.4 6.3 4.1 50.7 8.5 4.2 63.9 38.0 107.1 103.2 22.2 28.2 63.2 2.8 5.5 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.9 6.4 2.0 1.5 0.0 3.3 0.0 3.8 0.0 1.2 1.1 28.1 0.6 2.4 0.0 24.9 110.1 0.0 2.8 0.0 1.2 0.0 0.0 0.2 0.0 6.0 9.0 14.6 1.5 0.9 8.2 0.0 14.2 3.0 5.4 0.5 0.0 0.9 4.5 0.0 1.4 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.9 0.1 54.4 35.9 107.1 28.2 71.3 18.2 62.3 13.7 21.0 38.0 63.9 15.8 19.9 66.7 22.2 103.2 10.0 14.4 63.2 2.4 4.4 1.2 2.7 3.1 2.3 5.2 1.8 3.9 3.3 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase, non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;lymphoid tissue: 63.7" "Cell line enhanced" "Detected in some" "HEL: 16.4;HL-60: 35.6;HMC-1: 48.1;NB-4: 15.5;THP-1: 16.4;U-937: 25.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basal ganglia: 9.4;thalamus: 2.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 17.0;NK-cells: 9.9;T-cells: 10.6" "Region enriched" "Detected in single" 10 "basal ganglia: 5.5" "Region enriched" "Detected in all" 4 "basal ganglia: 10.9" "CAB009530, HPA019118" Approved "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favourable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 2.6 3.1 0.5 27.1 9.4 24.5 0.6 0.4 0.5 0.6 2.3 0.6 0.0 3.0 0.7 0.6 1.7 0.8 2.9 0.5 0.6 0.8 1.1 0.9 3.2 16.5 1.2 0.2 0.6 0.6 0.0 0.7 0.4 0.8 1.3 1.9 0.7 5.3 0.3 0.4 0.6 3.7 0.9 1.6 15.4 1.4 12.7 2.9 63.7 0.9 0.6 24.8 2.9 0.8 2.6 2.6 17.0 1.1 9.9 10.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 16.4 0.0 0.0 0.0 35.6 48.1 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 4.8 15.5 0.0 0.0 0.7 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.4 0.0 0.0 0.1 0.0 0.0 7.2 1.8 10.3 0.0 25.7 0.0 11.5 1.1 17.0 10.6 1.1 9.5 1.9 7.1 10.5 2.0 2.6 5.3 6.4 7.1 9.9 0.4 2.6 9.0 2.8 0.5 9.4 0.4 0.5 0.6 0.8 1.2 0.2 0.8 2.9 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase, non-receptor type 9" P43378 15 75463251-75579289 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favourable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 16.8 12.8 15.0 11.8 17.7 9.2 15.7 11.1 20.0 17.4 22.4 10.5 12.0 17.0 18.9 16.4 10.9 16.4 13.5 12.2 13.1 14.6 17.9 14.0 16.0 12.6 11.6 12.4 16.0 12.3 16.6 12.5 18.9 13.2 16.9 19.5 18.4 14.6 21.9 6.8 11.8 30.6 17.6 15.6 15.6 13.4 8.7 7.5 16.3 34.4 8.0 13.9 14.7 15.3 3.3 5.9 4.6 5.7 6.7 7.2 2.9 9.1 11.0 17.2 11.5 12.9 14.2 5.7 13.7 21.4 17.4 15.9 6.6 13.9 14.8 11.1 23.4 13.8 37.0 15.8 17.6 18.3 9.4 8.3 7.9 7.0 19.4 12.5 12.8 18.4 16.6 13.9 21.8 14.5 5.5 5.4 19.6 6.0 8.9 11.8 15.8 5.6 17.5 8.5 4.1 21.9 14.8 6.8 14.1 19.5 10.9 21.0 5.6 21.7 16.7 16.7 5.4 10.9 14.6 8.0 8.3 13.8 9.7 19.1 16.4 4.6 4.3 4.2 7.2 5.7 5.7 3.3 5.0 6.1 5.9 2.3 2.1 3.9 0.7 6.7 5.4 3.9 3.1 2.9 15.0 17.7 11.1 20.0 13.1 14.6 11.6 12.4 13.2 7.5 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase, receptor type A" P18433 20 2864184-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles 21000 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: " "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favourable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 21.9 18.5 55.6 14.3 48.6 16.4 23.3 44.5 56.0 29.7 19.7 37.5 9.4 14.7 26.3 18.7 22.7 26.5 21.3 14.0 45.9 41.1 22.1 13.5 21.6 16.9 38.0 46.7 28.6 14.9 41.5 23.4 29.0 52.5 23.5 20.0 18.5 16.7 21.8 8.2 21.0 15.3 25.7 52.6 17.9 16.3 27.4 30.4 20.6 32.4 8.5 20.4 22.9 19.2 7.7 5.7 7.9 6.7 6.2 11.0 3.7 20.5 12.6 36.3 11.1 40.2 73.4 7.7 15.5 30.3 19.2 23.5 15.0 28.6 13.5 12.2 20.7 22.1 14.6 22.1 21.7 20.8 9.4 19.2 5.3 19.0 14.4 19.2 9.1 32.8 22.9 15.8 16.7 26.5 19.2 17.3 19.0 8.4 22.2 21.8 14.0 10.1 17.0 17.6 16.8 16.4 16.0 20.1 19.3 15.0 25.5 23.0 15.9 16.5 18.9 17.1 8.5 19.1 13.6 12.7 17.6 17.8 7.9 18.2 16.0 7.9 4.8 7.5 11.0 4.8 9.0 7.7 7.4 7.9 3.7 5.1 7.4 9.0 6.0 6.2 6.7 5.7 8.1 3.7 55.6 48.6 44.5 56.0 45.9 41.1 38.0 46.7 52.5 30.4 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase, receptor type B" P23467 12 70515866-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 11.1;HUVEC TERT2: 27.5;TIME: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "memory B-cell: 3.5" "Lineage enriched" "Detected in single" 7 "B-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" 6700000 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: " "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favourable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favourable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 23.5 7.0 4.5 5.5 7.0 0.1 22.9 3.6 6.1 11.3 8.0 4.3 7.1 5.3 17.1 8.5 5.8 8.2 11.4 17.6 6.2 5.1 18.7 12.0 39.9 3.3 6.9 4.6 5.5 4.4 4.9 5.7 23.3 7.8 6.1 8.2 16.0 3.6 7.1 11.8 4.7 7.4 13.3 7.3 22.9 5.2 3.7 4.3 0.7 14.0 12.2 2.6 6.5 14.7 3.5 0.1 0.2 0.0 0.4 0.3 0.2 1.9 0.1 0.8 0.1 0.0 0.0 0.4 0.4 1.9 1.0 2.4 0.0 1.5 0.7 11.1 0.3 6.8 0.1 0.3 3.5 0.5 0.3 0.1 0.7 0.4 0.1 0.3 0.0 0.0 0.3 2.7 0.0 27.5 1.5 0.4 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.7 0.3 5.1 0.7 0.0 0.4 0.7 0.0 1.6 0.0 0.6 40.2 0.4 0.4 0.1 2.3 0.5 0.3 0.3 0.2 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 4.5 7.0 3.6 6.1 6.2 5.1 6.9 4.6 7.8 4.3 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase, receptor type C" 1 198638457-198757476 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 116.9;lymphoid tissue: 172.5" "Cell line enhanced" "Detected in some" "Daudi: 51.0;HEL: 28.8;HL-60: 26.0;MOLT-4: 38.5;THP-1: 21.4;U-266/70: 23.9;U-266/84: 21.6;U-698: 30.6;U-937: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: , CAB068221: , HPA000440: AB_1078468" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 9.8 2.9 3.4 48.0 6.2 36.1 4.3 1.3 3.5 3.1 5.6 2.8 0.5 4.9 2.9 3.9 4.8 5.6 8.8 4.9 3.9 4.5 4.4 5.2 27.5 93.2 7.9 1.3 2.9 2.1 0.3 2.5 4.5 5.3 4.2 5.8 3.3 10.7 1.0 1.7 2.5 22.2 4.5 13.2 89.3 6.5 2.3 5.3 172.5 4.6 3.9 53.2 13.1 3.7 28.5 42.8 94.7 103.8 53.7 76.1 116.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 51.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 28.8 0.0 0.0 0.0 26.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.8 0.0 0.0 38.5 15.7 0.1 0.1 1.1 0.1 0.1 0.0 0.0 0.3 0.4 0.0 0.1 0.1 0.0 21.4 0.3 0.0 0.2 0.1 0.1 23.9 21.6 30.6 0.0 23.3 0.1 20.8 52.0 56.3 76.1 99.7 64.5 28.5 52.9 72.7 42.8 26.8 60.2 60.3 94.7 53.7 103.8 6.4 54.6 116.9 3.4 6.2 1.3 3.5 3.9 4.5 7.9 1.3 5.3 5.3 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase, receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;parathyroid gland: 37.5" "Cell line enhanced" "Detected in some" "AF22: 23.0;HAP1: 5.0;HSkMC: 7.8;NTERA-2: 5.6;RH-30: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" 2500000 Vesicles Nucleoplasm "HPA054829: " "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favourable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.6 1.7 19.7 1.5 19.2 1.1 1.1 27.9 32.1 5.6 5.4 21.7 0.2 4.0 3.6 1.8 1.5 3.6 2.6 3.0 18.0 13.5 11.4 4.2 3.4 0.9 17.9 22.3 12.7 1.7 37.5 4.4 9.4 15.1 3.3 5.3 1.9 1.1 2.0 1.0 1.2 4.6 2.8 29.7 1.4 1.7 2.5 18.5 0.0 3.2 0.0 1.0 2.7 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 23.0 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.6 4.7 0.6 0.0 0.0 0.0 0.2 7.8 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.7 0.0 5.6 1.4 2.8 8.5 0.0 2.1 0.0 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.7 19.2 27.9 32.1 18.0 13.5 17.9 22.3 15.1 18.5 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase, receptor type E" P23469 10 127907061-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 91.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.9;NB-4: 15.0;TIME: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 91.0;plasmacytoid DC: 65.7" "Group enriched" "Detected in all" 11 "dendritic cells: 65.7;granulocytes: 91.0;monocytes: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 16.8 18.5 12.5 24.0 12.5 39.5 11.0 7.4 15.3 4.8 9.2 14.5 1.6 9.6 5.1 8.1 8.8 6.2 10.7 12.3 15.0 12.2 4.4 4.8 22.5 20.0 12.5 6.5 4.3 3.1 3.4 6.5 8.0 9.8 4.5 9.8 4.8 7.0 3.1 1.9 4.9 12.7 7.7 14.3 26.4 7.7 4.3 10.9 11.4 6.6 6.1 12.2 10.0 5.0 1.2 65.7 91.0 25.5 4.0 5.4 4.9 2.0 0.4 0.2 0.0 1.2 0.2 3.6 0.0 0.0 0.8 1.7 0.8 12.0 1.5 1.3 1.0 1.1 1.0 5.8 0.3 1.8 0.9 0.1 0.7 0.0 2.0 7.4 5.6 0.4 3.3 2.9 5.9 19.9 0.0 0.9 1.2 1.8 2.2 15.0 0.1 0.7 8.8 1.2 2.9 3.3 8.6 0.0 1.2 3.4 0.6 0.1 0.3 9.4 37.5 0.8 0.8 3.7 4.1 0.4 0.6 2.1 5.5 5.8 0.0 17.4 25.5 19.3 5.4 9.0 3.2 0.9 2.4 3.6 13.3 1.2 1.7 2.9 91.0 4.0 6.8 65.7 3.5 4.9 12.5 12.5 7.4 12.7 15.0 12.2 12.5 6.5 9.8 10.9 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase, receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.7;SK-BR-3: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" 95000000 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favourable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 37.1 5.5 22.4 10.4 18.1 0.9 30.7 6.8 19.5 14.2 34.3 16.8 34.4 30.7 12.3 33.4 41.4 32.2 20.0 6.3 17.2 15.0 12.0 45.6 15.7 5.8 17.2 18.5 10.4 25.3 17.5 10.3 38.1 16.1 30.9 23.1 5.9 41.9 23.6 2.9 46.8 35.5 16.8 11.2 2.0 21.8 4.3 15.8 4.6 12.5 11.7 14.9 21.4 21.3 0.9 0.0 0.2 0.0 0.0 0.0 0.7 30.4 14.6 9.6 11.3 2.2 0.1 53.7 17.5 7.0 14.5 12.4 15.5 41.5 0.0 4.9 7.6 23.9 11.1 38.5 17.6 0.3 13.9 0.1 10.0 14.1 6.8 0.2 0.2 2.2 22.2 20.8 34.6 21.5 4.7 1.4 5.3 17.6 0.2 0.2 14.5 4.0 10.6 17.0 0.7 5.6 46.1 14.3 5.3 17.4 61.4 2.3 17.7 3.2 16.9 0.3 23.2 1.4 23.3 0.6 0.5 0.0 1.4 0.7 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 22.4 18.1 6.8 19.5 17.2 15.0 17.2 18.5 16.1 15.8 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase, receptor type G" P23470 3 61561569-62297613 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.5;HSkMC: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" 520000000 "Plasma membrane" "HPA000546: , HPA064237: " "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favourable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 22.2 18.0 12.9 10.1 10.7 1.2 26.1 8.1 16.4 17.2 13.9 5.2 12.0 5.6 15.8 19.0 6.4 13.1 15.7 12.4 24.5 9.9 20.2 8.2 38.9 10.2 8.3 10.5 16.6 6.0 58.6 11.9 13.1 15.1 11.3 8.9 23.3 7.9 17.2 19.2 6.6 8.4 17.4 12.7 9.2 8.7 11.4 5.0 0.1 21.7 7.0 3.2 10.0 14.6 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 11.4 0.0 35.5 18.1 5.5 7.0 11.6 7.5 10.2 5.3 0.2 0.2 4.1 8.3 0.1 5.5 5.5 12.0 0.6 3.1 0.5 0.0 6.1 11.9 2.9 0.0 26.3 2.2 10.7 13.0 8.1 0.0 7.0 6.8 3.0 0.0 0.0 7.0 0.0 4.6 3.5 0.2 7.8 3.3 0.8 1.8 1.7 0.0 2.7 0.0 0.1 18.5 10.6 10.1 16.9 5.9 2.2 2.6 0.0 8.1 1.3 12.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 12.9 10.7 8.1 16.4 24.5 9.9 8.3 10.5 15.1 5.0 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase, receptor type H" Q9HD43 19 55181248-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 29.6;intestine: 84.3;lymphoid tissue: 21.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.0;HHSteC: 10.4;K-562: 12.1;PC-3: 8.2;SK-MEL-30: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042300 Approved Mitochondria Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 0.5 8.9 0.5 5.2 0.7 0.0 0.5 0.5 1.0 0.7 39.9 0.6 0.5 30.1 0.5 0.5 0.6 0.0 29.6 0.5 1.3 1.6 0.6 7.8 0.6 0.5 3.0 0.5 0.6 2.8 0.0 3.0 0.6 0.5 1.0 9.6 0.6 0.5 0.5 0.5 0.0 84.3 0.7 6.9 21.2 10.2 0.5 0.5 0.5 0.5 1.0 0.8 1.1 2.4 0.0 0.7 0.0 1.5 0.0 0.0 0.0 5.6 3.5 0.0 1.4 1.1 3.1 0.1 0.1 3.0 0.6 1.2 1.5 8.0 0.0 0.3 0.5 0.0 0.0 0.0 0.7 0.0 0.1 0.4 0.1 4.0 10.4 0.0 4.1 0.8 2.5 2.0 3.1 0.1 12.1 0.5 0.0 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.4 0.0 0.0 0.3 0.8 0.0 3.6 18.2 0.0 1.6 0.0 0.8 1.2 0.4 0.0 0.0 3.0 0.0 0.9 0.1 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.7 0.5 0.5 1.3 1.6 3.0 0.5 0.5 0.5 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase, receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 25.3;RPTEC TERT1: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in all" 4 "granulocytes: 12.2;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" 840000000 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favourable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 5.6 3.7 10.4 17.7 13.9 22.6 5.6 4.9 9.5 6.1 9.0 8.8 12.3 8.4 3.9 7.6 2.9 5.0 6.7 5.2 9.5 9.2 13.3 12.2 12.2 22.6 10.8 9.4 3.0 9.1 21.1 14.5 20.3 8.3 7.8 8.1 12.9 12.9 9.0 4.6 4.3 13.4 5.5 6.7 33.0 13.8 3.1 9.9 6.7 18.8 0.9 9.7 6.0 3.9 1.0 1.8 12.2 5.3 1.2 2.1 0.9 3.5 13.4 5.9 3.2 0.9 2.1 2.0 3.6 2.6 6.3 4.7 0.8 19.8 3.3 25.3 9.1 2.7 9.2 0.9 7.7 21.7 2.5 0.9 16.6 1.2 5.8 1.2 20.6 1.5 0.3 1.7 0.4 3.8 1.2 2.1 2.2 7.6 0.0 7.4 4.6 2.1 0.7 0.7 1.7 24.6 5.2 4.0 1.2 10.0 5.7 9.0 6.3 9.1 12.4 5.0 5.2 10.0 10.9 0.5 0.7 5.5 5.7 3.8 18.1 0.9 1.5 3.4 2.1 2.5 1.4 1.0 1.2 1.5 1.0 0.7 1.0 1.3 12.2 1.2 5.3 1.8 1.1 0.9 10.4 13.9 4.9 9.4 9.5 9.2 10.8 9.4 8.3 9.9 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase, receptor type K" Q15262 6 127968779-128520674 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.3;naive B-cell: 4.8;naive CD8 T-cell: 1.6" "Group enriched" "Detected in many" 7 "B-cells: 4.8;T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" 13000000 "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: , HPA054822: " "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favourable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 12.0 5.2 18.6 10.7 20.3 1.2 20.9 4.7 24.4 12.2 21.9 25.6 11.2 25.7 12.1 10.3 9.1 13.2 29.6 11.4 17.2 12.6 13.3 23.6 17.4 5.7 20.5 19.3 15.6 25.7 11.4 12.2 17.4 14.9 16.3 23.4 3.9 18.3 17.5 9.1 13.5 27.4 14.6 17.1 6.4 24.6 2.7 23.7 15.3 10.1 6.5 7.6 18.4 15.1 4.8 0.0 0.0 0.0 0.4 1.6 0.2 4.4 4.8 2.9 0.2 6.1 8.2 2.9 12.1 23.5 5.0 4.6 8.0 3.7 0.0 3.7 11.1 12.7 3.0 9.6 7.1 13.4 4.9 0.1 7.4 11.1 7.5 0.0 0.4 6.0 8.9 10.5 14.4 13.7 0.0 0.2 12.3 9.0 6.8 0.0 3.0 6.2 24.5 6.2 0.8 12.4 9.2 15.3 0.0 12.5 14.0 0.7 3.8 0.3 23.1 7.9 5.5 15.3 10.9 0.1 1.6 0.0 10.1 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 4.8 0.4 1.6 0.0 0.4 0.0 0.0 0.1 0.2 18.6 20.3 4.7 24.4 17.2 12.6 20.5 19.3 14.9 23.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase, receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD8 T-cell: 7.2" "Group enriched" "Detected in many" 50 "dendritic cells: 2.7;T-cells: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" 76000000 "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: " "unprognostic (2.59e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favourable (1.07e-4)" 31.4 14.1 9.5 6.3 22.2 0.6 23.6 10.4 17.2 11.0 13.6 6.2 28.1 4.7 15.4 10.9 8.1 13.6 18.1 33.5 10.5 15.0 16.9 6.5 22.0 7.8 8.5 12.0 15.7 7.6 16.3 21.9 18.3 23.2 10.6 6.6 18.3 7.4 21.8 26.0 7.3 8.7 14.1 9.3 12.1 11.0 12.2 9.1 2.9 31.1 7.3 6.3 18.6 25.3 0.0 2.7 0.0 0.0 0.0 7.2 1.4 1.5 11.3 5.4 0.0 34.8 24.1 13.1 13.8 12.2 9.3 13.8 10.3 2.4 0.0 13.6 16.6 0.1 0.0 4.8 12.9 0.1 2.5 0.0 7.5 5.0 9.9 0.0 0.1 27.4 10.2 5.1 14.7 9.3 0.0 4.7 7.4 0.2 4.5 0.1 0.9 2.5 0.1 4.7 20.9 22.8 19.4 0.4 3.0 0.4 0.0 11.6 0.0 0.0 9.6 19.2 12.1 9.1 2.4 0.4 0.1 0.0 16.4 0.0 3.5 0.0 0.0 0.0 4.5 0.0 1.8 0.0 6.0 7.2 0.1 0.0 1.7 3.1 0.0 0.0 0.0 2.7 1.0 1.4 9.5 22.2 10.4 17.2 10.5 15.0 8.5 12.0 23.2 9.1 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase, receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.6;pancreas: 28.9;pituitary gland: 43.4" "Group enriched" "Detected in some" 8 "U-2 OS: 19.8;U-87 MG: 73.7" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA007152: , HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavourable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 1.7 22.3 19.3 4.7 35.7 1.7 1.3 17.3 89.6 1.2 2.4 2.5 0.0 2.5 1.5 1.2 1.5 1.3 1.5 1.4 21.6 40.1 1.5 1.2 1.4 1.3 14.4 19.8 1.3 28.9 1.2 43.4 1.4 22.0 1.4 1.9 3.1 1.2 1.3 1.2 2.0 2.5 2.4 3.5 1.3 6.0 1.4 2.1 0.0 1.5 0.0 1.2 2.7 0.0 0.1 0.3 0.2 0.0 0.0 0.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 2.5 0.0 6.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 4.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.2 73.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.6 3.7 19.3 35.7 17.3 54.0 21.6 40.1 14.4 19.8 22.0 2.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;HDLM-2: 21.5;NB-4: 22.1;SCLC-21H: 12.2;SH-SY5Y: 12.4;THP-1: 10.8;U-87 MG: 15.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavourable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.3 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 0.0 0.4 0.0 0.0 21.5 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.3 22.1 3.0 0.7 0.0 0.7 0.1 0.0 0.0 12.2 12.4 0.0 0.0 0.0 0.0 10.8 3.2 5.0 1.9 0.0 0.3 0.1 0.0 0.0 15.1 9.0 3.6 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase, receptor type O" Q16827 12 15322397-15597399 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;intestine: 28.5;kidney: 21.6" "Cell line enhanced" "Detected in some" "NTERA-2: 9.3;SCLC-21H: 5.7;SH-SY5Y: 11.2;THP-1: 4.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.2;intermediate monocyte: 10.5;memory B-cell: 8.3;myeloid DC: 7.4;naive B-cell: 7.0;naive CD4 T-cell: 2.9;non-classical monocyte: 10.5;plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory region: 215.3" "Low region specificity" "Detected in many" HPA034525 Enhanced "Intracellular and membrane" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 3.3 1.2 16.2 3.1 26.1 0.6 1.1 1.0 15.3 1.7 10.4 1.5 0.0 2.0 4.5 2.1 0.8 1.2 1.6 0.7 11.3 10.6 21.6 1.6 6.7 3.2 4.8 8.8 0.7 0.6 0.6 3.8 4.4 4.0 0.7 28.5 1.1 0.8 1.1 0.5 0.7 1.9 7.1 2.6 3.6 1.0 0.9 3.5 0.0 0.5 0.0 3.5 1.7 0.5 8.3 9.5 0.0 10.5 0.1 2.9 2.7 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 0.0 0.9 2.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.3 0.1 0.2 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.7 9.3 0.1 0.0 0.0 0.1 0.2 0.3 5.7 11.2 1.3 0.0 0.1 0.1 4.6 0.0 0.1 0.4 0.0 0.4 1.4 0.1 0.4 0.1 0.3 1.7 0.0 5.2 0.0 0.0 10.5 0.0 8.3 1.7 0.4 7.4 7.0 2.9 1.3 0.0 0.1 10.5 9.5 1.3 2.7 16.2 26.1 1.0 15.3 11.3 10.6 4.8 8.8 4.0 3.5 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase, receptor type R" Q15256 12 70638073-70920843 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 56.1" "Group enriched" "Detected in some" 5 "HDLM-2: 14.0;RT4: 26.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 56.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "cerebellum: 100.5" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: " "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.40e-5)" 0.4 3.8 18.8 1.6 11.3 0.3 0.4 56.1 20.9 0.5 11.2 0.1 0.0 5.1 8.4 0.3 0.4 0.5 1.9 0.4 8.6 4.9 0.4 0.4 0.4 0.4 1.3 13.2 0.4 0.6 0.3 0.9 0.7 3.3 0.5 7.8 0.8 0.4 2.1 0.4 0.4 11.3 4.9 3.1 0.4 4.4 0.4 1.4 0.0 0.4 0.0 0.3 4.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.5 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 26.7 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.8 11.3 56.1 20.9 8.6 4.9 1.3 13.2 3.3 1.4 PTPRS ENSG00000105426 "Protein tyrosine phosphatase, receptor type S" Q13332 19 5158495-5340803 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 40.7;HaCaT: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 82 "plasmacytoid DC: 13.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" 92000000 "Plasma membrane, Cytosol" "HPA054747: " "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favourable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 59.1 17.3 14.4 9.4 14.8 3.1 32.0 27.6 53.3 28.7 11.4 29.6 14.4 4.6 21.4 15.4 13.3 24.0 22.2 18.6 15.9 15.1 10.7 6.9 13.9 8.6 20.5 12.1 29.2 38.4 10.5 16.6 4.3 12.0 23.1 3.6 28.9 21.5 20.1 11.9 23.8 6.5 17.5 13.8 8.3 12.7 10.8 18.7 4.4 21.1 7.2 7.5 19.1 22.7 0.0 13.4 0.0 0.0 0.0 0.1 0.0 3.6 20.9 18.9 40.7 8.7 7.1 2.5 6.3 7.5 7.7 6.3 0.2 2.0 0.0 15.0 10.6 41.3 5.0 0.0 3.4 0.4 8.0 0.0 8.6 13.0 4.0 0.0 4.7 7.5 1.8 1.6 0.3 0.2 5.8 0.0 3.1 15.4 1.6 3.9 10.6 8.9 0.0 4.2 0.0 1.5 7.3 14.5 19.9 6.0 1.1 11.5 7.3 1.5 0.8 6.9 11.9 15.7 7.6 2.1 0.0 12.0 3.5 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 14.4 14.8 27.6 17.6 15.9 15.1 20.5 12.1 12.0 18.7 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase, receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.5;fallopian tube: 17.0" "Cell line enhanced" "Detected in some" "BEWO: 4.5;RPMI-8226: 1.2;SCLC-21H: 2.9;U-266/70: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 5.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.6 0.8 5.0 0.6 11.1 0.5 4.6 1.6 23.5 1.6 0.7 0.9 0.0 1.2 0.5 1.8 0.5 17.0 0.7 0.8 4.7 6.5 0.6 0.9 2.1 1.0 2.2 12.6 0.5 0.9 0.5 4.1 4.6 5.1 0.8 0.6 0.5 2.0 4.6 0.5 0.8 1.0 0.5 1.4 0.7 1.8 2.8 0.9 4.9 0.5 0.0 1.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 11.1 1.6 22.6 4.7 6.5 2.2 12.6 5.1 0.9 PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase, receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavourable (7.92e-4)" "prognostic unfavourable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" 6.0 3.2 3.1 1.7 5.8 0.6 16.0 6.7 12.7 24.8 3.7 2.6 6.1 1.3 9.5 4.7 3.9 14.5 7.0 8.9 4.5 5.1 3.9 7.0 11.4 1.2 5.2 5.3 12.2 12.0 12.1 8.1 14.3 21.4 11.0 2.3 18.7 11.3 17.9 14.7 7.3 1.7 6.5 6.6 2.4 4.5 4.4 0.9 0.3 4.9 2.1 2.0 12.2 17.6 0.4 0.0 0.0 0.5 0.0 0.2 0.0 3.1 4.3 0.2 0.6 12.1 0.4 39.7 3.4 3.0 0.1 0.2 3.7 14.1 0.5 6.7 0.6 17.1 15.7 11.0 0.0 0.2 7.9 0.6 4.8 15.7 5.1 0.0 0.7 5.6 5.9 0.0 1.0 0.1 0.1 0.5 3.1 5.2 0.2 0.1 6.5 2.0 0.0 4.6 0.2 4.8 15.8 13.4 17.4 3.4 10.8 2.3 6.4 0.7 2.8 0.6 3.9 1.0 0.4 0.3 0.4 0.0 7.8 0.7 0.8 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.1 5.8 6.7 12.7 4.5 5.1 5.2 5.3 21.4 0.9 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase, receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 118.1" "Group enriched" "Detected in some" 9 "AF22: 92.1;NTERA-2: 25.6;WM-115: 40.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" 950000 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavourable (9.36e-4)" 2.0 2.5 33.1 2.3 44.1 1.5 4.0 15.4 118.1 2.4 2.2 19.3 0.0 1.9 1.6 2.0 7.0 1.7 1.9 2.0 39.6 15.9 1.6 1.6 2.1 1.5 18.6 17.8 2.0 3.3 1.5 1.6 1.6 67.6 2.1 2.3 0.8 2.4 2.0 1.5 19.3 1.9 2.4 76.6 2.1 9.8 1.7 23.6 0.0 1.5 1.8 3.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.1 0.0 0.1 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 44.1 15.4 39.6 39.6 15.9 18.6 17.8 67.6 23.6 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077027-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 63.9" "Cell line enhanced" "Detected in some" "MCF7: 17.6;NB-4: 11.6;SH-SY5Y: 89.7;THP-1: 26.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.1;monocytes: 6.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "midbrain: 95.5" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" 260000 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavourable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 15.2 1.1 1.8 1.3 0.7 1.2 4.1 9.0 1.9 3.1 0.9 1.1 1.5 0.9 0.6 1.2 0.7 1.0 1.2 1.5 5.8 1.0 11.7 0.7 0.8 17.5 1.2 0.8 1.3 63.9 6.3 0.8 16.8 2.2 1.5 2.8 13.6 2.0 4.5 1.1 2.6 1.1 2.8 0.6 2.1 2.0 0.0 0.1 0.8 5.1 0.6 1.9 1.4 0.2 2.1 0.0 6.7 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 11.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 89.7 0.0 0.0 0.0 1.2 26.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.7 2.1 0.3 0.4 1.1 1.3 4.1 9.0 1.5 5.8 17.5 1.2 16.8 0.0 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774022-64181498 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 31.2" "Cell line enhanced" "Detected in many" "ASC diff: 19.4;ASC TERT1: 24.3;CACO-2: 16.6;HHSteC: 18.5;HSkMC: 19.9;NTERA-2: 20.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 13.0" "Group enriched" "Detected in some" 5 "NK-cell: 3.3;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;NK-cells: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA057016 Approved Microtubules "Intracellular and membrane" 2800000 Microtubules "HPA057016: " "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 5.5 1.7 1.3 3.5 2.7 0.4 3.4 13.0 2.8 16.7 8.8 2.2 4.4 2.0 14.2 5.0 4.9 5.5 10.7 10.6 1.3 1.1 3.6 0.8 9.7 1.1 1.0 2.4 8.3 9.8 31.2 3.6 2.9 3.0 10.9 3.9 7.9 2.8 6.3 2.1 4.5 4.1 17.8 1.1 3.1 9.2 2.7 0.9 1.8 1.5 4.6 2.1 10.2 8.8 0.4 1.1 0.1 0.1 3.3 0.1 0.0 7.0 5.5 2.8 0.3 19.4 24.3 1.9 1.3 3.8 0.7 2.0 16.6 2.2 0.1 3.2 3.2 1.5 0.0 1.3 0.5 0.0 1.7 0.0 0.7 0.2 18.5 0.0 0.0 19.9 5.1 10.2 12.0 0.3 0.0 0.1 5.1 0.1 0.1 0.0 20.2 2.8 0.1 0.1 4.3 4.1 0.1 1.6 6.5 0.4 0.1 2.9 0.0 0.0 3.8 1.5 2.9 10.8 2.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.1 3.3 0.1 1.1 0.0 0.0 1.3 2.7 13.0 2.8 1.3 1.1 1.0 2.4 3.0 0.9 ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950162 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 12.0;HHSteC: 31.7;HSkMC: 26.4;U-266/70: 18.3;U-266/84: 12.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "pons and medulla: 6.6" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 3.9" "Lineage enriched" "Detected in single" 6 "T-cells: 3.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 13.5" HPA021868 Uncertain "HPA021868: AB_1856406" "unprognostic (9.38e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.76e-2)" "unprognostic (2.66e-1)" "prognostic unfavourable (9.86e-7)" "unprognostic (2.16e-3)" "unprognostic (9.13e-2)" "prognostic unfavourable (4.28e-8)" "unprognostic (1.25e-2)" 4.4 4.3 0.7 5.3 1.1 0.0 3.6 0.2 0.8 23.4 20.7 2.9 11.1 1.9 29.1 9.1 8.0 8.1 18.7 8.5 1.0 0.9 2.0 0.5 4.2 0.7 0.3 0.0 19.1 3.1 20.3 1.3 7.1 6.6 20.3 2.1 11.0 1.2 13.1 1.1 2.9 6.2 30.0 0.3 4.7 10.5 5.2 0.3 2.6 7.9 1.9 3.3 23.7 18.1 0.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 12.0 0.0 2.6 0.2 3.4 0.2 3.1 2.0 3.8 0.0 0.0 0.0 0.0 0.6 0.1 2.5 0.0 0.8 0.0 2.0 0.0 9.2 0.0 31.7 0.0 0.0 26.4 0.0 2.7 0.0 0.0 6.6 0.0 0.0 0.2 0.0 1.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.5 0.2 0.0 0.0 7.1 0.1 0.0 0.0 2.4 1.0 0.0 18.3 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.8 1.0 0.9 0.3 0.0 6.6 0.3 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117288300-117425855 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 38.6;lung: 20.2" "Group enriched" "Detected in some" 5 "HSkMC: 9.3;hTCEpi: 19.3;LHCN-M2: 13.4" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 7.4;olfactory region: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles Vesicles "HPA049098: , HPA072424: " "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.3 0.2 0.2 0.0 0.4 0.0 0.2 0.2 7.4 0.2 0.4 0.0 7.9 0.0 0.2 38.6 0.2 0.2 0.0 0.2 0.2 0.2 0.4 0.2 20.2 0.0 0.2 2.5 0.2 0.2 0.0 0.3 0.7 0.0 0.2 0.3 0.0 0.2 2.3 0.2 0.7 0.3 0.0 0.2 0.2 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 9.3 19.3 0.2 1.7 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.8 0.0 2.3 1.5 0.1 1.8 0.0 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 7.4 0.2 0.2 0.2 2.5 0.0 0.0 RYK "D3S3195, JTK5, JTK5A, RYK1" ENSG00000163785 "Receptor-like tyrosine kinase" 3 134065303-134250744 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034117, HPA045503, HPA075430" Uncertain Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "CAB034117: AB_2183048, HPA045503: , HPA075430: " "unprognostic (7.84e-2)" "unprognostic (5.82e-2)" "unprognostic (2.22e-2)" "unprognostic (2.34e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (2.60e-4)" "unprognostic (2.60e-2)" "unprognostic (6.59e-2)" "unprognostic (1.62e-1)" "unprognostic (1.07e-3)" "unprognostic (9.66e-2)" "unprognostic (2.42e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-1)" "unprognostic (3.43e-1)" "unprognostic (2.85e-2)" 23.8 13.2 8.5 12.1 9.3 6.3 27.5 10.6 9.5 26.5 19.3 12.7 18.2 8.8 25.8 19.1 21.1 16.7 15.8 17.1 8.1 6.7 12.9 12.7 12.4 9.1 10.8 7.3 39.7 17.7 14.1 17.9 18.8 8.6 26.9 12.1 16.4 15.2 21.5 15.3 15.5 13.3 28.6 8.4 13.8 14.3 20.3 10.0 13.6 23.2 11.4 15.2 27.5 31.9 2.8 0.7 6.7 1.6 3.1 4.3 1.1 25.6 6.8 21.6 16.5 27.9 29.7 16.7 17.0 39.7 22.8 25.7 21.6 19.7 5.0 28.4 21.0 24.1 15.3 21.5 32.7 8.4 6.9 13.3 7.4 13.9 21.8 6.5 11.8 19.6 25.3 14.1 28.4 19.0 4.6 2.5 22.3 12.2 9.0 8.4 18.2 8.2 4.4 16.6 10.5 18.7 19.0 10.6 15.7 20.7 15.1 25.8 18.9 11.8 14.0 18.9 17.2 19.7 13.7 1.1 1.3 2.7 12.0 10.9 13.3 6.7 1.6 3.1 2.5 1.6 2.9 1.5 4.2 3.0 0.7 2.8 4.3 3.4 0.6 3.1 1.6 0.0 1.0 1.1 8.5 9.3 10.6 9.5 8.1 6.7 10.8 7.3 8.6 10.0 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" "Nucleoplasm, Actin filaments, Cytosol" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavourable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favourable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 16.8 15.7 30.4 10.1 51.9 3.3 11.6 27.1 59.3 15.3 11.4 14.9 10.6 10.8 14.1 21.7 15.9 26.8 11.7 23.1 28.3 27.0 11.3 8.0 13.1 8.8 21.5 34.9 26.4 20.4 26.5 20.3 8.0 34.2 18.3 10.0 15.6 23.3 25.1 7.4 13.0 9.8 18.3 14.0 9.8 13.4 4.9 12.2 3.7 20.2 6.6 11.4 12.4 11.4 9.4 9.4 26.7 18.4 9.7 21.0 15.6 12.4 19.4 2.5 5.1 20.7 10.3 3.3 19.2 9.9 7.2 4.6 3.2 10.5 8.0 15.9 23.4 11.6 3.3 14.5 4.8 8.7 5.1 5.1 11.8 7.3 15.6 9.6 9.1 9.3 23.0 10.3 15.9 14.9 4.4 20.4 12.6 26.9 6.8 5.0 1.4 13.7 3.0 4.3 16.5 9.2 10.0 4.3 4.2 16.5 15.3 7.8 14.3 7.5 20.6 8.3 8.4 18.6 13.0 11.5 10.2 2.3 24.3 8.5 10.0 15.5 9.8 26.7 21.0 17.5 20.1 9.4 14.5 16.9 9.4 7.5 12.5 14.6 15.5 9.7 18.4 4.5 8.0 15.6 30.4 51.9 27.1 59.3 28.3 27.0 21.5 34.9 34.2 12.2 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 35.5;HBEC3-KT: 33.0;PC-3: 32.1;RT4: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 5.3;non-classical monocyte: 4.4" "Group enriched" "Detected in many" 6 "dendritic cells: 3.0;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Plasma membrane,Cell Junctions,Cytosol" 20000000 "Plasma membrane, Cell Junctions" Cytosol "CAB004023: AB_2106059, HPA030875: " "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavourable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavourable (1.63e-4)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favourable (5.22e-5)" 6.9 17.5 12.8 11.1 12.0 5.4 9.9 6.4 16.0 16.0 16.4 3.5 15.1 29.5 20.3 9.7 16.2 14.2 42.1 5.8 11.3 6.6 13.4 2.9 10.4 7.0 3.3 9.9 15.8 19.1 6.6 11.3 6.3 5.1 19.9 13.1 13.1 7.5 22.5 3.4 7.7 28.1 27.2 3.6 12.2 29.8 27.3 4.8 4.0 6.6 10.5 10.4 26.4 20.0 0.3 3.0 0.1 5.3 0.6 0.1 1.6 7.6 35.5 8.1 7.3 3.1 4.9 17.0 7.1 6.1 8.6 5.5 13.3 6.9 0.2 4.4 12.8 14.0 4.9 33.0 3.4 0.0 4.4 1.9 1.2 20.7 7.4 0.1 3.0 5.3 11.2 5.6 7.5 7.8 0.2 0.0 1.4 5.2 1.8 0.2 3.8 32.1 8.3 2.1 0.2 3.6 34.0 7.6 27.5 8.0 11.3 8.8 10.1 2.8 11.5 10.4 7.0 3.8 6.3 0.1 0.2 0.1 7.3 0.0 7.7 0.0 2.6 0.0 0.0 5.3 0.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.1 0.6 4.4 3.0 0.1 1.6 12.8 12.0 6.4 16.0 11.3 6.6 3.3 9.9 5.1 4.8 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 10.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.7;HaCaT: 2.6;MCF7: 4.9;RT4: 10.1;T-47d: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 8 "B-cells: 1.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: " "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.3 0.0 0.3 0.5 0.3 0.0 1.1 1.1 0.3 0.3 1.8 0.3 0.3 0.4 0.3 10.2 0.4 0.0 0.3 0.3 0.3 0.0 0.9 0.3 0.3 0.3 0.3 0.3 0.3 2.7 0.0 0.3 0.3 0.3 2.2 0.0 0.3 2.5 0.3 0.3 1.7 0.8 0.3 0.3 2.5 4.2 0.9 0.3 0.3 0.3 0.3 0.8 1.5 0.3 1.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 5.7 0.2 2.3 0.0 2.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.2 0.0 0.8 0.0 0.2 0.0 0.0 10.1 0.8 1.0 0.3 2.1 0.4 2.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 1.1 0.3 0.3 0.0 0.3 0.3 0.3 0.3 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavourable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.2 4.0 6.6 14.1 6.0 5.4 3.4 2.5 2.4 4.7 15.5 5.1 2.7 11.1 4.9 4.9 2.6 5.7 3.1 2.1 4.5 2.9 15.1 9.9 3.8 5.5 12.2 5.5 1.3 2.0 15.8 2.9 3.3 4.2 3.1 5.4 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.5 12.7 2.1 2.6 4.3 10.9 4.6 6.5 3.7 3.9 3.5 3.0 5.7 2.4 34.2 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain "CAB017189: , HPA057099: " "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 11.9 9.7 6.2 5.3 17.3 11.9 3.6 5.9 6.8 9.8 10.4 5.2 4.5 9.9 9.5 7.0 13.9 7.6 8.6 11.4 3.5 13.6 6.9 9.9 7.7 8.2 7.3 14.9 13.9 5.8 10.4 6.9 22.4 4.9 7.8 6.9 3.3 34.5 7.5 4.6 5.0 16.6 15.8 17.4 17.0 9.4 10.5 11.7 8.6 9.6 17.2 6.4 7.7 12.3 6.7 13.7 11.7 7.1 11.8 7.8 24.8 7.9 5.8 6.1 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 23.6;RT4: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.1 6.7 0.1 0.2 4.7 4.9 7.3 4.0 5.4 2.1 2.0 7.2 16.3 0.3 12.5 3.7 23.6 2.2 17.0 1.1 1.3 2.5 1.5 10.8 2.9 3.3 0.3 6.0 4.3 15.8 3.1 3.2 2.4 0.0 0.6 2.5 20.8 0.2 3.0 1.5 5.4 7.6 0.2 1.1 6.9 35.7 1.4 2.2 9.4 14.0 4.4 19.6 5.2 3.8 1.7 3.7 4.7 1.1 0.6 0.3 0.2 4.8 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618939-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8;stomach 1: 16.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.2;HDLM-2: 10.8;HMC-1: 11.9;HUVEC TERT2: 16.4;TIME: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA040468: , HPA048569: " "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.6 0.3 2.6 2.3 10.6 1.0 3.8 0.1 13.4 2.2 14.4 0.7 0.5 2.1 0.5 1.1 8.9 1.9 6.2 0.1 1.8 1.6 0.5 0.3 1.2 2.4 1.8 4.2 0.4 0.3 0.0 8.4 3.4 2.1 10.6 15.8 0.0 7.8 2.6 0.2 2.6 10.3 0.6 0.6 1.0 16.0 0.3 0.7 0.0 0.4 0.6 2.8 4.3 3.6 0.0 0.0 0.4 0.0 12.5 1.9 0.2 2.9 0.1 0.0 0.4 0.0 0.0 0.9 4.8 0.5 2.2 2.1 1.6 18.2 0.2 3.1 1.2 0.8 0.9 5.0 4.8 10.8 0.3 0.7 1.3 0.1 0.0 1.4 11.9 0.2 0.2 3.4 0.2 16.4 0.2 0.2 5.2 1.7 0.1 0.8 2.7 1.3 0.0 1.4 0.2 1.6 9.4 0.6 0.0 2.7 2.9 0.0 2.3 0.3 15.2 0.6 2.5 0.3 0.6 0.0 0.6 0.1 2.1 0.1 3.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.4 12.5 0.0 0.0 0.0 0.2 2.6 10.6 0.1 13.4 1.8 1.6 1.8 4.2 2.1 0.7 STYXL1 "DUSP24, MK-STYX" ENSG00000127952 "Serine/threonine/tyrosine interacting like 1" Q9Y6J8 7 75996338-76048004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050261 Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA050261: " "unprognostic (6.24e-2)" "unprognostic (1.12e-1)" "unprognostic (7.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.88e-3)" "unprognostic (9.33e-2)" "unprognostic (1.50e-3)" "unprognostic (4.77e-2)" "unprognostic (8.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.47e-3)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (3.17e-2)" "unprognostic (2.28e-1)" "prognostic favourable (8.22e-4)" 9.4 19.2 16.0 10.2 23.1 12.7 17.5 12.8 19.8 15.7 15.1 19.6 13.9 10.5 10.3 21.0 21.1 28.2 9.4 13.2 16.6 12.1 14.8 20.1 11.3 13.7 20.9 13.5 15.4 30.0 15.9 19.9 24.6 16.8 16.6 20.1 12.2 16.0 13.9 12.4 19.3 10.3 14.0 17.0 17.4 14.0 25.0 19.7 20.8 19.9 12.1 19.5 14.8 14.6 19.7 23.0 30.8 29.3 24.7 22.1 17.4 19.7 10.6 8.3 11.1 13.2 14.4 8.7 8.9 12.7 14.5 14.4 12.2 18.0 4.6 4.5 11.8 8.8 13.5 17.9 21.1 14.7 5.9 5.6 5.0 10.9 18.8 7.8 10.3 14.0 21.0 17.4 43.7 14.1 18.1 13.9 12.9 16.0 3.0 33.4 7.0 25.6 11.9 7.0 12.2 18.4 12.9 11.0 11.4 8.3 19.2 22.3 21.1 15.1 7.0 12.5 5.3 13.7 12.6 15.1 9.6 15.7 11.1 14.9 19.4 30.8 29.3 25.8 13.7 25.3 15.2 19.7 13.2 15.2 23.0 15.6 11.7 13.2 24.6 24.7 23.7 15.1 22.1 17.4 16.0 23.1 12.8 19.8 16.6 12.1 20.9 13.5 16.8 19.7 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.5" "Cell line enhanced" "Detected in many" "Daudi: 38.7;HEL: 22.3;HL-60: 30.8;HMC-1: 20.5;REH: 25.8;THP-1: 23.7;U-698: 18.3;U-937: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 21.4;eosinophil: 23.3;intermediate monocyte: 19.0;memory B-cell: 23.1;myeloid DC: 24.9;naive B-cell: 17.5;neutrophil: 32.8;NK-cell: 8.7;non-classical monocyte: 16.4;plasmacytoid DC: 18.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" 1000000 "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.2 3.3 6.0 38.1 9.6 18.2 6.7 1.1 4.5 3.7 10.3 6.7 1.5 12.3 2.3 6.7 16.2 6.9 6.6 5.5 7.2 3.2 8.6 2.5 13.7 36.4 9.1 2.5 2.1 8.9 25.9 3.1 5.0 6.1 4.1 8.3 2.8 8.9 1.8 1.4 8.3 22.2 3.5 11.3 38.5 7.4 5.5 7.9 30.5 18.1 7.8 32.2 8.6 7.5 23.1 24.9 32.8 21.4 8.7 0.1 10.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 38.7 1.1 0.0 6.0 0.8 3.2 0.0 0.0 5.3 22.3 0.0 0.0 0.0 30.8 20.5 0.0 4.4 0.0 0.4 0.0 0.6 3.1 0.0 4.7 0.0 13.5 0.2 0.0 25.8 0.0 10.6 0.8 5.8 2.0 1.8 0.0 2.7 0.0 2.5 23.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.3 0.0 21.7 0.0 1.4 21.4 23.3 0.1 19.0 0.1 23.1 0.0 0.0 24.9 17.5 0.0 0.0 32.8 8.7 16.4 18.5 0.0 10.2 6.0 9.6 1.1 4.5 7.2 3.2 9.1 2.5 6.1 7.9 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269864 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.4;HMC-1: 16.4;U-266/70: 16.3;U-266/84: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 13.3;eosinophil: 11.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: " "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favourable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 3.9 4.5 0.8 7.2 1.1 9.8 5.1 0.6 2.0 3.4 4.8 0.5 8.4 2.8 3.0 21.6 9.5 3.6 2.1 3.3 0.9 0.9 4.0 5.7 6.4 7.0 1.5 0.3 2.9 2.9 2.6 6.4 2.0 3.2 2.0 2.5 3.0 6.8 4.7 2.1 8.1 6.5 3.0 1.2 6.7 2.2 5.5 0.6 4.4 4.4 5.8 11.1 3.2 6.5 0.9 1.3 13.3 0.6 2.9 0.4 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.4 1.8 1.0 2.2 0.0 1.7 1.5 1.6 0.0 0.5 0.9 0.0 1.5 0.1 0.7 10.4 0.7 0.1 0.0 1.7 16.4 0.0 0.2 1.4 0.0 0.0 5.7 0.4 3.2 0.7 1.0 3.7 0.3 0.7 2.4 2.2 0.0 2.8 0.7 0.0 0.2 0.5 0.2 0.4 0.6 3.3 0.0 0.0 0.0 2.2 0.0 16.3 11.6 2.1 0.0 2.3 0.1 13.3 0.5 11.0 0.1 0.6 0.3 0.9 0.1 0.4 1.3 0.6 0.4 0.4 0.4 2.9 0.1 0.1 0.0 0.3 0.8 1.1 0.6 2.0 0.9 0.9 1.5 0.3 3.2 0.6 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230175 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 35.8;NTERA-2: 17.8;TIME: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 2.2" "Lineage enhanced" "Detected in single" "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" 7750000 8300000 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: " "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favourable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favourable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 28.6 7.8 8.1 4.6 5.9 0.4 17.9 3.4 5.4 10.8 4.7 4.6 3.4 3.2 14.5 5.3 6.7 5.9 9.1 13.0 7.1 6.1 25.4 8.7 27.8 2.9 6.9 3.4 6.1 4.5 3.5 4.0 36.3 6.9 5.4 4.7 12.4 3.4 5.5 7.8 3.0 5.3 10.6 5.3 23.4 4.0 3.7 3.5 0.3 9.7 8.4 2.4 6.4 12.4 0.0 0.1 2.2 0.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.2 2.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.0 0.0 0.6 0.0 0.0 0.7 0.0 0.8 0.3 35.8 0.0 0.0 0.3 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 38.8 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 8.1 5.9 3.4 5.4 7.1 6.1 6.9 3.4 6.9 3.5 TESK1 ENSG00000107140 "Testis-specific kinase 1" Q15569 9 35605305-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 30.9 19.4 13.5 10.8 20.5 5.6 25.4 13.4 26.4 14.3 15.2 15.0 9.7 13.7 15.3 13.4 11.0 12.0 13.0 12.8 13.7 13.1 10.5 10.0 11.5 10.7 14.1 10.3 17.0 16.0 13.1 15.7 12.3 12.6 15.1 8.8 14.2 14.6 21.0 47.2 13.7 12.7 16.9 7.3 11.0 12.9 28.4 12.9 9.2 13.0 12.3 9.0 16.6 20.9 1.0 2.3 0.3 1.8 2.1 4.9 1.5 9.9 9.3 6.4 10.6 25.7 10.7 7.3 11.4 10.2 10.6 6.8 5.4 2.8 18.1 6.5 11.4 3.4 4.0 8.2 2.0 11.6 5.4 2.6 8.8 4.7 15.0 2.2 8.7 10.4 13.0 8.3 11.4 7.4 3.0 6.5 10.5 11.0 5.0 11.0 3.9 10.9 7.8 3.9 4.2 7.8 4.6 5.2 6.4 6.5 7.9 4.8 9.4 3.3 6.4 23.6 10.1 16.9 6.8 4.0 5.6 6.7 17.1 2.6 5.3 0.0 1.8 0.3 3.4 0.4 3.0 0.8 1.4 4.9 2.1 1.0 1.5 1.6 0.0 2.1 0.8 2.3 0.3 1.5 13.5 20.5 13.4 26.4 13.7 13.1 14.1 10.3 12.6 12.9 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.0;RT4: 12.7;SK-MEL-30: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027257: AB_10602477, HPA063869: " "unprognostic (2.95e-1)" "prognostic favourable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.0 0.6 4.3 1.9 3.2 3.6 1.5 5.2 0.6 1.5 2.0 3.4 2.7 1.5 3.7 4.3 3.5 1.8 2.7 1.7 1.2 9.8 1.8 2.9 2.1 3.0 1.5 0.6 10.9 1.2 0.6 3.0 2.4 3.4 1.5 4.4 0.1 1.4 1.7 12.7 0.3 1.4 3.3 6.4 12.1 9.9 1.5 0.0 0.2 2.0 1.6 1.1 7.1 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300993-43323108 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "EFO-21: 27.9;HUVEC TERT2: 61.6;TIME: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "basophil: 3.4;NK-cell: 5.4" "Group enriched" "Detected in many" 22 "granulocytes: 3.4;NK-cells: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" 75000000 "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 39.4 5.4 3.9 6.6 6.0 1.0 43.6 2.5 6.0 10.8 8.4 4.5 4.2 4.5 18.6 10.9 7.8 10.2 11.1 15.1 4.9 4.2 9.4 10.8 22.0 13.1 6.4 3.1 7.0 3.0 2.7 5.1 39.9 5.5 8.6 3.0 6.9 6.0 6.9 17.8 4.2 5.8 12.1 5.3 14.8 5.1 5.1 3.8 1.1 13.9 10.2 3.1 9.0 14.7 0.0 0.2 3.4 0.0 5.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 5.1 0.3 0.0 2.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.5 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.4 0.0 0.1 0.0 0.0 3.9 6.0 2.5 6.0 4.9 4.2 6.4 3.1 5.5 3.8 TNK1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 6.4;HaCaT: 10.4;HBEC3-KT: 6.9;hTCEpi: 7.8;T-47d: 8.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 6.4;cerebellum: 11.4;cerebral cortex: 4.0;pons and medulla: 4.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 1.6;T-cells: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favourable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favourable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favourable (1.52e-4)" 3.4 0.6 1.1 2.2 6.4 0.4 7.9 11.4 4.0 5.4 11.7 0.4 7.7 7.1 5.1 5.3 7.2 3.5 6.3 2.0 1.0 0.4 4.6 6.9 3.2 2.7 1.5 0.8 4.4 6.8 5.4 2.7 2.5 4.3 8.9 4.5 7.7 10.5 4.8 1.8 8.3 11.3 5.1 0.7 2.4 9.6 2.2 0.6 0.6 11.6 5.7 5.2 4.5 4.4 1.6 0.1 0.4 0.0 0.0 3.8 0.6 6.4 1.0 0.2 0.4 0.0 0.0 4.3 0.2 0.0 0.4 0.4 3.3 3.0 0.0 2.6 0.3 10.4 0.0 6.9 0.1 0.7 1.5 0.0 3.7 1.8 0.4 0.0 0.2 0.1 7.8 0.0 1.2 0.0 0.8 0.0 0.0 4.9 0.6 0.0 0.9 0.9 0.2 0.2 0.7 4.8 3.0 0.2 0.5 3.5 5.2 1.0 8.6 0.1 1.7 0.2 0.8 0.2 0.0 0.5 1.0 0.1 0.1 0.4 0.5 0.0 0.0 0.0 1.0 0.0 1.9 1.6 1.8 1.2 0.1 1.5 3.3 3.8 0.4 0.0 0.0 0.0 0.8 0.6 1.1 6.4 11.4 4.0 1.0 0.4 1.5 0.8 4.3 0.6 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041954 Approved Approved Cytosol Cytosol "HPA041954: AB_10794164" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavourable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favourable (1.00e-4)" 9.2 7.6 36.3 16.2 27.6 38.9 8.5 20.7 43.7 6.0 6.3 17.6 3.8 6.6 8.0 6.6 13.0 10.7 6.5 10.6 28.4 21.8 4.1 7.2 9.3 18.1 21.6 31.8 8.6 7.8 5.1 19.3 8.4 20.0 10.8 3.9 5.3 16.8 8.2 30.5 37.1 6.9 7.6 10.3 17.0 12.1 7.7 21.8 3.4 4.6 9.8 12.8 7.7 12.3 6.1 3.1 6.3 3.2 0.9 1.9 1.2 31.3 3.0 5.1 5.4 7.1 4.5 30.5 6.0 5.8 3.6 3.3 4.8 24.3 9.1 21.2 8.2 11.2 4.4 7.5 1.1 21.4 5.6 8.2 10.2 3.5 3.2 4.2 4.1 3.3 11.9 5.0 6.0 4.6 3.3 12.7 3.4 23.1 1.8 15.4 4.8 11.3 5.3 6.1 9.2 3.2 15.2 6.2 6.3 3.9 15.9 7.8 26.0 5.3 7.5 8.4 4.9 4.4 16.8 27.6 3.0 5.6 7.5 13.8 6.2 2.0 2.4 0.9 1.9 3.2 1.1 2.7 1.8 1.0 1.1 6.1 1.4 1.3 6.3 0.9 2.8 3.1 0.2 1.2 36.3 27.6 20.7 33.3 28.4 21.8 21.6 31.8 20.0 21.8 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205199-66420543 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 21.3;neutrophil: 17.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: " "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavourable (8.16e-6)" "prognostic unfavourable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavourable (3.73e-5)" 15.4 12.8 16.7 9.8 28.2 5.6 11.2 12.2 19.2 34.0 7.7 8.8 3.4 3.4 20.2 13.8 10.8 10.9 34.2 6.6 26.1 22.2 13.4 38.9 9.0 5.9 15.3 12.2 11.5 7.1 8.1 19.6 23.2 28.1 15.5 7.9 9.7 5.4 15.8 2.9 6.2 5.9 35.7 27.5 9.0 10.0 19.6 11.4 0.3 10.7 3.2 5.2 27.2 19.9 6.3 0.1 21.3 1.1 3.9 2.0 0.8 4.2 2.6 6.7 8.6 20.6 16.5 2.1 8.2 18.9 10.1 14.3 8.2 2.5 0.5 6.6 16.7 3.3 6.3 9.3 13.4 1.2 3.6 0.9 6.4 6.3 24.4 0.6 0.7 23.3 7.3 19.3 8.5 12.2 0.4 3.8 15.4 2.3 0.0 1.1 6.1 3.5 2.9 5.4 4.3 10.4 4.6 3.9 16.7 10.3 0.8 22.0 3.3 1.7 23.2 12.9 8.2 9.2 14.8 3.5 4.8 1.7 11.4 2.5 18.2 21.3 1.1 10.7 0.4 0.0 0.3 2.4 0.2 0.3 0.1 6.3 1.1 2.0 17.3 3.9 0.0 0.0 0.0 0.8 16.7 28.2 12.2 19.2 26.1 22.2 15.3 12.2 28.1 11.4 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521983-26596717 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 71.0;pancreas: 192.5" "Cell line enhanced" "Detected in all" "HMC-1: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" 33000 "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favourable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 5.8 8.4 4.7 3.7 3.6 5.2 9.0 2.1 6.9 4.6 2.9 3.0 7.4 3.5 4.7 31.8 4.5 4.1 3.2 5.2 5.2 3.2 5.7 20.0 10.7 4.8 3.7 3.6 2.4 192.5 1.1 2.9 11.0 3.2 3.8 2.3 4.0 2.8 7.9 8.6 4.0 3.1 3.2 2.8 8.9 3.0 4.8 3.1 3.0 12.2 2.2 5.2 4.5 6.7 4.3 20.0 71.0 15.1 57.2 46.4 35.2 4.2 3.1 4.1 2.0 8.8 6.7 5.7 9.6 17.3 7.8 7.2 2.1 2.2 7.2 2.5 17.2 6.7 3.0 6.6 4.5 2.9 5.8 17.4 1.9 4.4 3.6 2.0 56.0 7.2 10.6 7.9 2.7 14.4 17.4 22.7 5.9 4.8 8.0 13.6 5.3 3.1 7.5 5.5 20.1 2.3 4.8 3.1 2.1 4.4 3.9 5.3 1.8 8.4 11.4 9.7 21.9 7.9 9.2 7.4 10.2 6.9 7.3 7.8 8.7 71.0 13.4 18.6 46.4 14.5 13.0 4.1 10.9 34.5 8.4 4.3 5.4 31.4 28.4 57.2 15.1 20.0 12.2 35.2 4.7 3.6 2.1 6.9 5.2 3.2 3.7 3.6 3.2 3.1 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 69 "testis: 78.6" "Cell line enhanced" "Detected in some" "BEWO: 7.5;K-562: 8.7;Karpas-707: 7.1;MCF7: 5.2;PC-3: 5.3;RPMI-8226: 9.6;U-2 OS: 4.7;U-266/70: 8.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" Cytosol "Endoplasmic reticulum" "HPA049690: , HPA068342: " "unprognostic (3.63e-2)" 0.1 0.0 0.0 0.7 0.2 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.8 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.4 0.0 0.9 0.0 78.6 0.0 0.4 0.1 0.4 0.8 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 7.1 0.0 5.2 0.0 0.0 1.2 5.3 0.0 0.0 9.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 4.7 2.4 0.0 8.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavourable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.7 1.1 3.5 13.6 15.5 9.6 22.7 27.8 10.9 10.2 19.8 12.1 6.6 17.4 21.2 9.5 31.7 18.0 17.1 18.3 10.7 8.9 0.0 21.5 12.0 0.4 1.0 15.9 10.2 12.8 20.0 20.5 19.3 9.9 12.3 15.6 14.2 9.7 11.0 43.9 8.2 5.7 8.6 16.6 9.7 9.1 9.9 5.6 9.3 16.4 5.3 10.2 10.2 6.6 24.8 4.6 15.5 11.0 3.6 20.1 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134256 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 43.5;lymphoid tissue: 49.1;placenta: 28.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HMC-1: 11.0;U-266/70: 5.4;U-266/84: 6.7;WM-115: 24.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 43.5" "Group enriched" "Detected in many" 26 "NK-cells: 43.5;T-cells: 17.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles Vesicles "HPA062482: " "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 1.8 1.5 0.3 15.3 0.4 3.9 1.5 0.2 0.6 0.8 2.1 0.3 0.2 1.3 1.3 11.6 2.4 2.6 1.7 0.7 0.2 0.4 2.1 2.8 4.0 49.1 0.5 0.5 0.5 1.0 0.4 1.3 28.4 0.6 0.9 1.0 1.0 6.1 0.2 0.5 1.7 7.9 0.4 0.4 17.8 1.0 1.7 0.2 14.0 1.9 0.2 19.3 2.4 1.4 0.0 0.1 1.1 0.0 43.5 17.5 10.6 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 4.7 0.0 1.4 0.0 0.2 0.0 0.0 0.4 0.2 0.1 2.3 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.0 0.0 2.0 0.0 0.8 0.3 0.0 0.0 1.3 1.2 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.4 0.0 0.0 0.3 0.1 5.4 6.7 0.4 0.0 0.4 24.8 1.1 0.0 0.3 13.2 0.0 17.4 0.0 6.8 6.4 0.0 0.0 17.5 11.9 0.8 43.5 0.0 0.1 5.1 10.6 0.3 0.4 0.2 0.6 0.2 0.4 0.5 0.5 0.6 0.2 TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380676 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favourable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favourable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favourable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favourable (4.16e-4)" 16.8 19.0 22.9 36.0 22.6 49.4 17.5 24.4 23.9 17.8 19.4 26.7 13.9 20.0 19.3 20.2 15.0 16.8 21.8 17.0 18.3 14.0 24.0 34.4 27.5 31.5 24.7 17.4 20.0 21.3 19.0 24.8 13.9 19.1 21.1 18.6 21.6 24.4 15.4 15.6 24.4 23.8 16.7 17.9 47.9 18.5 6.4 22.8 33.9 20.9 13.5 34.7 16.7 15.1 5.8 15.8 22.9 13.4 5.3 9.1 7.3 8.5 12.5 7.5 11.7 10.0 14.1 7.2 11.7 12.0 14.9 16.4 9.6 5.7 13.0 13.8 13.1 8.6 9.0 13.8 7.9 22.9 14.0 24.0 24.9 23.5 15.6 10.1 27.7 13.6 9.8 16.9 10.0 14.4 10.1 36.4 13.1 26.9 14.8 62.3 2.4 21.9 14.8 6.4 13.3 12.1 27.6 7.0 8.7 11.5 12.1 8.4 6.7 17.2 12.2 20.1 7.2 23.1 13.7 30.0 23.3 11.9 10.0 21.1 11.2 6.6 13.4 17.0 9.1 10.2 5.9 5.6 5.5 8.1 15.8 5.8 3.8 5.1 22.9 5.3 9.7 9.0 6.8 7.3 22.9 22.6 24.4 23.9 18.3 14.0 24.7 17.4 19.1 22.8 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583586 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 48.2" "Cell line enhanced" "Detected in many" "BEWO: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved 6400000 "HPA071245: " "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 18.3 4.1 18.7 2.1 16.6 1.5 7.7 27.3 39.2 2.3 1.8 25.6 1.2 2.3 5.0 4.2 12.7 11.7 3.1 2.5 15.1 7.8 6.4 1.6 3.2 1.9 19.6 18.2 48.2 9.5 1.3 0.8 5.9 14.0 3.3 1.7 1.7 2.4 6.7 1.4 13.0 2.9 4.8 23.1 5.4 3.6 17.9 16.6 0.0 1.8 2.2 4.1 2.9 2.8 1.2 1.0 5.0 0.9 1.0 0.8 0.2 4.7 3.1 9.9 10.8 9.3 6.4 33.5 6.9 4.4 6.9 6.4 17.6 1.6 0.1 8.9 5.6 11.2 11.1 1.7 3.2 2.7 7.4 1.4 10.0 8.3 6.6 2.4 0.2 2.0 3.5 5.2 1.8 5.1 8.7 2.0 3.7 4.5 1.1 0.4 22.9 3.2 14.7 9.0 1.7 0.6 9.2 11.9 3.4 6.5 10.3 7.7 8.5 2.8 3.9 13.7 6.0 10.1 10.4 0.8 1.6 1.4 8.3 15.8 8.2 2.6 0.9 0.8 0.6 0.5 0.6 0.7 0.6 0.8 0.3 1.2 0.7 0.7 5.0 1.0 0.5 1.0 0.5 0.2 18.7 16.6 27.3 32.7 15.1 7.8 19.6 18.2 14.0 16.6 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 14.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" 4300000 "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 26.2 13.1 17.0 9.4 15.6 2.6 47.2 6.7 12.8 15.8 23.8 8.9 13.7 18.2 13.1 17.4 22.0 10.7 14.9 17.9 14.8 12.4 22.6 43.2 23.6 13.7 15.8 6.6 13.2 21.4 16.7 10.7 31.3 16.8 12.2 17.3 6.5 23.7 21.0 10.6 12.3 24.8 18.8 16.8 34.5 15.5 13.6 12.0 8.1 16.8 15.6 7.1 21.9 17.5 0.1 0.1 14.7 0.0 1.0 2.5 0.6 14.2 7.1 22.4 17.5 13.5 16.7 26.4 9.5 19.4 11.2 15.4 16.8 10.5 0.0 10.1 16.1 8.3 20.9 16.8 22.0 0.0 7.1 4.2 7.0 11.7 11.0 3.2 7.6 12.7 18.1 16.9 18.9 37.8 18.4 6.3 15.9 9.8 1.9 4.2 14.2 9.1 2.4 17.6 1.2 16.3 16.9 4.6 5.3 19.6 14.9 12.4 10.3 6.8 32.5 27.7 30.7 20.8 25.5 5.5 2.7 0.8 10.5 4.7 16.4 14.7 0.0 0.9 2.5 0.0 1.6 0.1 0.5 1.4 0.0 0.0 1.2 1.9 0.0 1.0 0.0 0.1 0.1 0.6 17.0 15.6 6.7 12.8 14.8 12.4 15.8 6.6 16.8 12.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713560-97739862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 37.4;lymphoid tissue: 107.1" "Cell line enriched" "Detected in some" 13 "MOLT-4: 61.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 41 "gdT-cell: 37.4;MAIT T-cell: 25.4;memory CD4 T-cell: 19.6;memory CD8 T-cell: 29.2;naive CD4 T-cell: 14.3;naive CD8 T-cell: 21.9;NK-cell: 26.4;T-reg: 19.9" "Group enriched" "Detected in many" 53 "NK-cells: 26.4;T-cells: 37.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002625, HPA003134" Enhanced "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favourable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favourable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favourable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavourable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 2.2 0.5 0.3 18.1 0.6 11.2 1.5 0.7 0.6 1.2 3.7 0.7 0.3 2.9 1.2 1.1 1.7 1.5 2.8 0.9 0.4 0.8 2.2 2.3 5.8 28.1 0.8 0.6 0.9 1.3 0.0 0.7 0.9 0.6 2.1 0.6 1.0 5.5 1.0 0.7 1.0 12.3 0.7 0.7 24.8 3.2 1.4 0.6 107.1 2.5 1.1 20.8 3.0 1.7 0.4 0.2 0.5 0.2 26.4 37.4 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 61.5 0.1 0.0 0.0 2.4 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.1 37.4 0.1 25.4 0.0 19.6 29.2 0.0 0.4 14.3 21.9 0.5 26.4 0.2 0.2 19.9 14.3 0.3 0.6 0.7 0.6 0.4 0.8 0.8 0.6 0.6 0.6