Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"
ALK	CD246	ENSG00000171094	"ALK receptor tyrosine kinase"	Q9UM73	2	29192774-29921566	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 8.1;pituitary gland: 17.9"	"Cell line enriched"	"Detected in some"	6	"SH-SY5Y: 26.4"	"Group enriched"	"Detected in some"	5	"glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA010694	Approved		Supported	"Plasma membrane"				"Plasma membrane"		"HPA010694: AB_1078133"	"unprognostic (4.96e-2)"	"unprognostic (1.11e-2)"	"unprognostic (1.45e-1)"	"unprognostic (4.56e-7)"	"unprognostic (7.17e-2)"	"unprognostic (1.71e-1)"	"unprognostic (9.07e-3)"	"unprognostic (6.29e-3)"	"unprognostic (1.18e-1)"	"unprognostic (1.01e-1)"	"unprognostic (2.67e-4)"	"unprognostic (3.70e-2)"	"unprognostic (2.06e-2)"	"unprognostic (7.15e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.38e-1)"	"unprognostic (3.61e-2)"	1.8	3.1	3.6	1.2	4.4	0.3	1.1	0.5	8.1	0.7	2.1	2.0	0.0	0.7	0.5	0.5	0.6	0.5	1.2	0.4	3.4	4.9	0.4	0.5	1.1	0.5	2.7	4.2	0.6	0.4	0.4	17.9	0.5	5.5	0.5	1.2	2.4	0.9	0.8	0.3	0.9	1.5	0.9	2.1	0.5	0.8	4.9	0.9	0.0	1.6	0.0	0.3	0.6	1.2	0.0	0.0	0.0	0.2	0.0	0.7	0.0	0.0	0.0	0.4	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.5	0.0	3.5	0.0	0.0	0.1	0.3	26.4	0.0	0.0	0.6	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	3.1	0.0	4.0	0.0	0.1	0.0	0.7	0.0	0.2	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	3.6	4.4	0.5	5.9	3.4	4.9	2.7	4.2	5.5	0.9
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC, WNT signaling pathway regulator"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 40.9"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA013349	Supported									"HPA013349: AB_1844913"	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"	7.2	5.4	40.9	6.4	21.7	8.5	6.3	19.1	39.7	6.8	7.1	10.3	2.0	6.6	6.3	3.9	8.4	5.0	5.5	7.4	37.9	12.9	6.9	6.2	6.7	5.6	23.6	20.7	7.6	4.6	13.8	7.2	5.5	39.1	5.9	6.9	4.0	4.0	4.9	7.0	6.1	8.8	8.1	19.1	6.2	5.4	5.3	20.6	3.6	6.5	2.7	6.2	6.2	3.9	3.8	3.0	12.9	2.9	3.0	3.4	1.1	8.3	7.7	12.8	9.3	10.6	8.8	5.2	13.5	6.4	7.5	8.9	6.1	6.8	16.1	13.1	17.2	6.8	13.1	11.0	12.4	9.6	8.9	12.2	11.1	4.6	5.2	6.1	6.7	7.4	7.6	12.7	8.4	10.4	15.0	5.6	10.9	5.8	7.0	3.1	4.6	2.7	6.0	15.9	7.8	6.9	10.6	13.0	7.8	12.8	5.0	5.5	6.9	5.0	16.6	15.3	7.4	15.0	10.2	4.4	6.6	6.3	8.5	11.4	8.5	10.4	2.9	5.0	3.4	1.4	2.9	3.1	1.8	2.1	2.3	3.8	2.9	2.8	12.9	3.0	2.5	3.0	1.6	1.1	40.9	21.7	19.1	31.4	37.9	12.9	23.6	20.7	39.1	20.6
APOBEC3B	"FLJ21201, PHRBNL"	ENSG00000179750	"Apolipoprotein B mRNA editing enzyme catalytic subunit 3B"	Q9UH17	22	38982347-38992804	"Cancer-related genes, Predicted intracellular proteins"	"Antiviral defense, Immunity, Innate immunity"	"Hydrolase, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.1"	"Cell line enhanced"	"Detected in many"		"A-431: 59.6;Karpas-707: 67.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in some"			"Cell type enhanced"	"Detected in many"		"memory B-cell: 10.2"	"Low lineage specificity"	"Detected in many"											"HPA056980, HPA066719"			Approved	Nucleoplasm				Nucleoplasm		"HPA056980: , HPA066719: "	"unprognostic (2.92e-2)"	"prognostic favourable (2.58e-5)"	"unprognostic (4.29e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.35e-1)"	"unprognostic (6.36e-2)"	"unprognostic (1.08e-2)"	"unprognostic (5.88e-2)"	"prognostic unfavourable (2.78e-4)"	"unprognostic (8.47e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.70e-1)"	"unprognostic (1.04e-1)"	1.6	2.3	0.3	4.4	2.2	20.1	1.4	0.3	1.2	2.3	9.9	0.7	0.3	5.8	2.0	2.4	4.6	1.2	2.2	1.6	0.6	0.2	3.6	0.9	2.5	4.3	0.3	0.3	1.7	5.7	0.4	0.3	6.4	0.8	2.1	10.0	1.3	4.8	0.3	4.1	1.9	8.8	1.0	0.7	10.4	3.8	2.0	0.3	5.9	3.3	0.3	12.0	2.0	2.4	10.2	0.8	1.7	5.8	2.2	3.8	5.9	59.6	6.7	2.6	16.1	0.3	1.5	4.5	5.5	4.8	10.6	13.9	12.8	10.9	0.6	5.0	5.5	25.6	0.3	1.1	10.7	21.6	0.6	17.2	1.4	3.3	0.1	14.2	10.4	0.5	0.1	11.0	0.5	4.1	9.6	67.6	16.4	1.6	0.0	8.0	0.0	6.0	0.4	25.8	21.5	2.1	10.1	0.4	0.0	0.0	0.0	3.7	7.9	4.1	2.5	11.7	20.4	1.8	0.1	15.0	4.1	0.0	8.3	15.9	23.7	0.5	1.3	0.0	0.3	5.8	0.0	10.2	0.8	0.5	0.8	3.2	0.0	0.4	1.7	2.2	1.8	0.1	3.8	5.9	0.3	2.2	0.3	1.2	0.6	0.2	0.3	0.3	0.8	0.3
AR	"AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1"	ENSG00000169083	"Androgen receptor"	P10275	X	67544032-67730619	"Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Receptor"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 49.0"	"Cell line enhanced"	"Detected in some"		"AF22: 11.0;BJ hTERT+: 9.6;HAP1: 14.1;LHCN-M2: 12.4;RH-30: 20.5;T-47d: 8.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Cell type enriched"	"Detected in single"	16	"plasmacytoid DC: 5.4"	"Lineage enriched"	"Detected in single"	16	"dendritic cells: 5.4"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000001, HPA065701, CAB065764"	Enhanced		Approved	Mitochondria				Mitochondria		"CAB000001: AB_2060174, CAB065764: AB_10620739, HPA065701: "	"unprognostic (1.34e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.49e-2)"	"unprognostic (5.95e-2)"	"unprognostic (1.04e-2)"	"unprognostic (3.35e-2)"	"prognostic favourable (8.77e-4)"	"unprognostic (4.99e-2)"	"unprognostic (1.72e-1)"	"unprognostic (7.79e-2)"	"unprognostic (2.30e-1)"	"unprognostic (2.29e-1)"	"prognostic favourable (1.03e-8)"	"unprognostic (8.23e-3)"	"unprognostic (8.90e-2)"	"unprognostic (4.23e-2)"	"unprognostic (7.97e-2)"	10.1	1.2	0.9	1.6	0.9	0.1	10.7	0.4	1.6	34.4	1.9	2.4	25.4	0.2	20.5	20.5	2.2	17.5	4.3	5.7	0.9	1.5	6.3	49.0	1.5	0.2	1.2	0.7	14.4	1.0	0.1	2.3	0.3	1.9	28.0	0.5	3.8	1.6	36.1	8.1	3.9	1.1	7.6	1.9	0.9	1.6	9.3	1.2	5.4	3.1	2.0	1.2	6.3	13.1	0.0	5.4	0.3	0.0	0.1	0.0	0.1	0.0	4.6	11.0	0.0	0.0	0.1	0.0	5.8	9.6	0.4	0.1	0.2	0.0	0.0	0.0	0.7	0.0	14.1	0.0	0.1	0.0	1.8	0.0	1.1	0.0	0.6	0.0	0.0	4.5	0.0	1.6	0.0	3.4	4.0	1.8	12.4	1.2	0.0	0.0	4.4	0.0	0.0	20.5	0.0	0.3	0.0	0.0	0.0	0.0	0.2	0.0	8.6	5.2	0.2	0.2	2.0	0.1	2.9	0.0	0.0	0.0	4.2	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.3	0.1	0.0	5.4	0.0	0.1	0.9	0.9	0.4	1.6	0.9	1.5	1.2	0.7	1.9	1.2
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222484-108369102	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 47.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Enhanced	Nucleoplasm,Vesicles				"Nucleoplasm, Vesicles"		"CAB000102: , HPA067142: "	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"	8.3	10.9	12.7	26.5	19.3	16.8	9.4	17.7	14.4	10.9	8.5	10.9	8.8	6.0	11.2	11.4	6.9	9.5	9.2	9.6	12.4	8.5	7.7	9.5	10.1	33.4	19.6	6.7	20.5	20.7	15.7	29.2	8.8	14.5	9.1	7.9	7.2	15.1	9.8	6.2	8.4	16.5	10.6	23.4	22.6	8.9	6.1	17.9	19.5	10.7	5.1	26.9	10.7	10.7	13.7	6.1	13.5	12.5	7.6	18.5	4.4	2.6	3.8	7.5	4.0	9.8	14.3	1.9	6.0	6.7	3.5	5.8	4.7	6.3	9.4	8.9	4.8	4.0	5.7	5.0	5.4	7.5	3.3	8.5	4.7	4.7	5.1	10.2	9.2	9.2	3.1	5.2	10.2	7.2	8.2	6.4	6.8	1.9	7.0	9.4	6.1	3.8	5.5	5.2	14.8	3.9	5.4	5.1	6.3	6.9	3.2	10.3	4.9	5.8	11.3	8.6	4.8	4.9	5.6	4.3	4.5	47.4	5.7	11.3	9.6	13.5	5.7	3.8	14.9	5.3	10.4	11.1	10.5	11.3	2.7	13.7	18.5	17.9	10.8	7.6	12.5	6.1	5.3	4.4	12.7	19.3	17.7	14.4	12.4	8.5	19.6	6.7	14.5	17.9
ATR	"FRP1, MEC1, SCKL, SCKL1"	ENSG00000175054	"ATR serine/threonine kinase"	Q13535	3	142449235-142578826	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Dwarfism, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054320			Supported	"Nucleoplasm,Golgi apparatus"				Nucleoplasm	"Golgi apparatus"	"HPA054320: "	"unprognostic (1.47e-1)"	"unprognostic (8.90e-2)"	"unprognostic (2.90e-1)"	"unprognostic (4.23e-2)"	"unprognostic (2.25e-2)"	"unprognostic (6.42e-2)"	"prognostic unfavourable (8.39e-5)"	"unprognostic (3.44e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.02e-1)"	"prognostic unfavourable (1.23e-5)"	"unprognostic (1.94e-1)"	"unprognostic (5.61e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.55e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.43e-1)"	10.5	24.3	7.7	11.4	15.9	10.1	14.8	11.3	14.6	10.1	8.5	10.0	10.4	6.0	14.7	16.8	9.4	12.1	9.3	8.8	9.8	7.1	9.6	12.0	10.3	16.0	10.0	8.1	12.3	13.6	18.0	22.5	8.8	12.5	11.0	11.2	9.5	12.5	10.8	7.7	11.2	10.9	9.8	8.8	14.2	9.0	15.3	9.7	19.0	13.8	7.7	15.1	10.9	10.6	5.8	2.8	2.2	4.0	6.7	6.0	0.8	22.5	11.1	7.4	8.4	10.6	11.6	8.8	12.4	7.0	9.3	9.6	5.2	7.2	18.4	12.9	8.8	14.6	10.9	11.5	14.1	5.9	7.2	10.1	8.4	5.0	4.7	16.9	5.7	9.1	6.4	8.8	10.5	9.6	7.0	8.3	9.5	9.9	12.7	7.0	7.1	7.9	10.6	10.8	13.3	9.4	10.5	5.3	5.3	22.9	8.3	8.1	12.1	6.9	12.4	9.5	4.8	12.3	13.3	10.8	6.4	17.1	12.3	6.6	7.5	0.7	2.7	2.2	4.4	4.0	6.0	3.1	3.2	4.2	2.8	5.8	4.1	4.0	1.7	6.7	2.5	2.5	2.4	0.8	7.7	15.9	11.3	14.6	9.8	7.1	10.0	8.1	12.5	9.7
AXIN2	"DKFZp781B0869, MGC126582"	ENSG00000168646	"Axin 2"	Q9Y2T1	17	65528563-65561647	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 13.3;CACO-2: 24.7;Hep G2: 36.9"	"Cancer enhanced"	"Detected in all"		"colorectal cancer: 33.4"	"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"naive CD4 T-cell: 5.1"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012283, CAB017783"	Approved		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"				"Nucleoplasm, Plasma membrane"	Cytosol	"CAB012283: AB_2290204, CAB017783: "	"unprognostic (1.31e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.48e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.57e-2)"	"unprognostic (8.84e-3)"	"prognostic favourable (6.58e-4)"	"unprognostic (1.98e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.45e-2)"	"unprognostic (2.10e-1)"	"unprognostic (2.74e-1)"	"unprognostic (1.25e-1)"	7.4	10.1	9.0	7.0	8.9	0.9	5.2	8.2	13.1	16.5	12.2	8.7	10.5	7.2	29.0	7.7	6.5	18.6	6.9	7.3	7.9	5.7	3.5	2.5	15.2	3.4	5.3	10.3	14.7	3.9	3.2	5.8	18.2	10.6	14.8	15.2	7.8	4.6	9.8	12.4	14.9	7.5	18.0	4.8	6.9	14.6	6.8	9.0	27.6	11.3	3.6	3.8	11.8	8.7	4.1	0.0	4.4	0.0	1.9	5.1	0.8	0.0	6.6	13.3	0.2	4.8	2.0	5.9	0.2	0.6	0.4	0.8	24.7	2.4	0.4	0.8	3.8	0.2	2.7	0.0	0.9	1.1	1.5	0.0	1.1	36.9	0.5	0.0	0.0	1.2	1.0	1.0	0.3	1.1	0.1	0.6	0.6	0.1	6.4	0.0	2.6	0.3	4.6	0.7	0.0	1.2	0.1	4.1	2.7	0.2	0.1	2.3	0.4	0.1	3.0	2.6	4.8	3.7	0.8	0.0	1.3	1.7	1.2	0.3	1.2	4.4	0.0	0.0	0.3	0.0	0.8	1.0	2.3	0.4	0.0	4.1	5.1	0.8	0.0	1.9	0.0	0.0	0.0	0.8	9.0	8.9	8.2	13.1	7.9	5.7	5.3	10.3	10.6	9.0
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401013-52410350	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	"Chromatin regulator, Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: , HPA055560: "	"unprognostic (1.52e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.96e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.41e-3)"	"unprognostic (8.53e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.15e-1)"	"unprognostic (4.64e-3)"	"unprognostic (3.30e-3)"	"prognostic favourable (3.29e-7)"	"unprognostic (6.37e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.92e-1)"	13.8	17.6	35.6	14.7	33.3	37.3	13.5	21.8	50.4	12.5	17.0	16.3	11.5	12.4	14.7	14.6	21.2	12.1	15.7	16.4	41.5	15.5	16.6	19.0	14.9	15.2	19.4	27.6	16.9	16.3	30.0	11.1	14.8	19.6	14.4	14.9	15.6	17.9	14.6	24.8	40.5	13.9	14.5	10.0	16.1	13.3	37.3	14.7	18.6	15.3	12.9	16.0	14.1	11.7	5.5	8.4	11.3	5.0	3.0	8.5	3.9	15.3	17.5	21.2	18.0	20.5	13.2	23.9	15.2	19.7	24.7	19.2	21.1	14.4	22.0	7.6	21.2	12.5	22.3	24.5	15.8	21.8	21.1	27.3	37.0	21.8	19.1	25.6	24.3	19.7	32.9	27.3	14.7	19.7	23.3	19.5	18.6	13.3	30.3	35.1	23.9	21.3	13.1	17.2	21.7	15.2	24.9	8.1	26.1	18.7	5.4	22.2	15.3	35.4	21.1	22.4	20.6	26.8	28.2	29.6	38.9	31.5	24.4	27.0	26.4	3.4	5.0	7.4	8.5	3.9	4.0	5.0	6.8	6.9	3.3	5.5	4.9	6.4	11.3	3.0	3.1	8.4	6.0	3.9	35.6	33.3	21.8	50.4	41.5	15.5	19.4	27.6	19.6	14.7
BARD1		ENSG00000138376	"BRCA1 associated RING domain 1"	Q99728	2	214725646-214809711	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"CAB034106, HPA035354, HPA044864"	Enhanced		Supported	"Nuclear speckles,Cytoplasmic bodies"				"Nuclear speckles"	"Cytoplasmic bodies"	"CAB034106: AB_2061237, HPA035354: , HPA044864: "	"unprognostic (4.85e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.37e-3)"	"unprognostic (2.57e-2)"	"unprognostic (1.03e-2)"	"unprognostic (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.92e-3)"	"unprognostic (2.80e-2)"	"unprognostic (7.41e-2)"	"unprognostic (1.94e-8)"	"unprognostic (3.94e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.08e-1)"	4.4	1.9	3.2	11.8	4.8	16.1	4.9	1.2	5.8	7.3	5.4	5.4	3.6	3.7	6.8	5.0	10.0	4.1	3.9	3.6	3.4	2.8	2.2	2.1	5.3	8.2	5.1	1.9	5.8	3.7	3.6	6.3	3.8	4.5	5.7	6.1	1.9	4.7	6.5	12.4	16.3	4.5	7.5	5.3	4.7	3.8	9.5	3.9	25.8	4.0	8.0	9.9	8.3	7.8	9.7	6.6	6.0	3.4	6.1	16.0	2.0	7.7	4.3	11.7	6.0	1.6	2.0	8.0	9.4	5.5	9.3	10.7	5.4	7.7	8.3	4.5	3.9	8.5	8.4	5.5	13.3	6.6	4.4	8.3	7.9	5.7	0.6	9.2	8.4	2.7	0.8	8.2	4.5	3.1	4.6	23.5	8.9	6.4	16.5	9.6	9.2	2.2	14.3	11.8	7.5	2.7	6.5	3.7	5.9	8.6	9.9	3.4	10.2	9.2	2.7	12.0	8.4	7.0	8.5	7.1	7.9	16.9	4.8	7.0	8.0	2.9	1.7	6.0	4.8	3.4	3.1	8.9	5.3	5.2	3.0	9.7	2.5	3.6	0.5	6.1	2.9	6.6	16.0	2.0	3.2	4.8	1.2	5.8	3.4	2.8	5.1	1.9	4.5	3.9
BLM	"BS, RECQ2, RECQL3"	ENSG00000197299	"Bloom syndrome RecQ like helicase"	P54132	15	90717327-90816165	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"lymphoid tissue: 36.7"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005689	Approved		Supported	Nucleoplasm,Cytosol				"Nucleoplasm, Cytosol"		"HPA005689: AB_1845372"	"unprognostic (2.77e-1)"	"unprognostic (3.82e-3)"	"unprognostic (4.03e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.75e-2)"	"unprognostic (9.89e-2)"	"unprognostic (6.12e-5)"	"unprognostic (2.82e-2)"	"unprognostic (4.55e-3)"	"unprognostic (5.24e-3)"	"unprognostic (1.80e-3)"	"unprognostic (9.12e-2)"	"unprognostic (1.55e-15)"	"unprognostic (6.53e-3)"	"unprognostic (6.55e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.83e-2)"	1.8	0.4	3.1	11.4	1.5	5.5	0.6	4.7	2.6	0.7	1.9	0.9	0.5	1.4	1.2	1.1	2.9	0.4	1.3	1.0	2.3	2.4	0.9	0.5	2.0	7.7	2.8	0.2	0.9	0.4	0.0	1.2	3.6	0.5	0.7	2.5	0.7	7.8	0.0	1.7	0.6	2.8	0.5	1.9	6.7	1.4	4.9	0.5	36.7	0.6	3.1	9.3	1.4	0.7	7.4	1.2	4.3	1.6	4.6	5.0	1.6	5.4	7.8	8.7	5.1	0.0	0.4	5.5	4.1	1.2	4.7	5.1	6.8	3.8	14.1	2.6	1.1	9.1	13.4	3.7	6.1	8.5	9.9	14.7	8.4	2.2	0.0	14.1	7.3	0.0	0.0	4.7	2.4	3.3	12.7	4.4	4.9	3.4	10.6	7.8	9.3	1.7	10.8	16.4	5.4	1.1	9.8	6.5	6.1	3.3	4.4	2.6	3.1	11.6	1.8	3.4	6.3	3.5	8.7	3.2	13.1	14.7	1.9	10.0	5.8	2.5	1.0	4.3	3.1	1.2	4.8	7.4	2.8	3.8	1.2	4.3	2.0	2.2	0.8	4.6	1.6	1.2	5.0	1.6	3.1	1.5	4.7	1.7	2.3	2.4	2.8	0.2	0.5	0.5
BMPR1A	"ACVRLK3, ALK3, CD292"	ENSG00000107779	"Bone morphogenetic protein receptor type 1A"	P36894	10	86756601-86932838	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019398	Approved		Approved	Cytosol				Cytosol		"CAB019398: "	"unprognostic (1.36e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.34e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.05e-3)"	"unprognostic (9.34e-2)"	"prognostic unfavourable (8.93e-4)"	"unprognostic (3.64e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (9.24e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.07e-1)"	8.9	7.0	9.4	7.9	12.4	0.9	10.7	14.1	9.2	19.4	20.6	10.9	7.7	6.2	16.3	12.3	8.4	10.9	10.8	11.0	7.7	6.1	8.2	4.6	7.4	2.9	7.3	7.6	16.1	10.6	10.0	14.0	7.4	8.5	12.8	9.3	10.9	12.6	14.2	8.4	11.3	9.8	16.5	12.2	3.4	12.1	7.8	9.2	0.3	19.4	7.8	5.7	16.0	11.4	1.8	1.1	3.6	0.8	0.9	1.4	0.3	7.5	3.8	14.7	12.5	7.7	5.0	2.6	7.6	8.0	4.5	5.2	6.5	6.7	2.3	3.5	9.7	8.1	6.5	8.3	6.6	2.5	3.7	2.9	3.6	10.7	4.1	4.0	20.4	4.4	3.5	6.0	4.4	0.0	4.5	1.6	5.2	3.2	2.6	3.2	8.0	1.8	0.0	5.8	0.0	9.2	7.2	1.5	4.8	8.5	4.3	5.1	7.3	2.0	3.8	3.2	5.2	6.6	7.0	0.4	7.0	2.9	2.8	2.7	2.6	2.0	0.8	0.6	1.4	0.5	0.9	1.8	1.4	1.2	0.3	1.5	1.0	1.1	3.6	0.9	0.6	1.1	0.7	0.3	9.4	12.4	14.1	9.2	7.7	6.1	7.3	7.6	8.5	9.2
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1, DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in all"	5	"dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"				"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: "	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"	4.8	4.3	6.0	9.6	11.3	15.3	5.1	12.9	10.6	5.4	9.2	3.4	6.8	4.3	5.4	5.5	9.1	5.5	3.3	6.5	6.6	5.3	4.2	7.7	4.9	13.0	7.5	5.9	5.1	4.7	4.2	11.0	5.3	10.5	4.1	10.4	3.7	5.4	7.4	7.3	8.3	6.7	5.5	9.2	5.9	5.1	17.6	7.0	10.9	15.6	7.3	14.6	5.5	5.6	2.0	9.1	9.7	12.7	1.4	1.3	10.7	15.5	25.2	13.9	11.1	2.3	5.2	13.6	18.3	7.9	15.4	14.7	15.3	12.1	35.9	3.4	7.0	18.0	18.9	10.2	25.9	16.4	13.8	16.9	19.8	13.2	0.5	30.1	14.7	1.4	1.7	23.2	7.4	7.9	25.4	15.4	14.5	10.3	25.2	9.9	7.6	6.7	17.4	29.3	14.7	5.7	15.1	9.6	10.3	14.1	4.7	6.9	12.4	13.9	5.2	13.8	11.2	17.8	19.1	7.2	17.6	27.6	11.1	17.9	14.4	4.6	12.7	1.8	1.3	4.0	1.3	1.1	1.3	1.0	9.1	2.0	1.2	1.3	9.7	1.4	1.5	1.4	0.4	10.7	6.0	11.3	12.9	10.6	6.6	5.3	7.5	5.9	10.5	7.0
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2, DNA repair associated"	P51587	13	32315474-32400266	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 23.2;testis: 16.9"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA026815	Uncertain		Approved	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"	2.4	1.0	0.6	13.8	0.6	11.6	3.2	0.6	0.6	1.8	4.0	0.2	0.2	1.4	1.5	2.7	3.0	1.0	0.7	2.1	0.6	0.7	1.0	1.4	3.5	5.3	0.7	0.5	1.4	3.3	0.4	0.7	7.0	0.8	0.9	2.0	0.1	1.8	0.3	3.3	1.8	3.2	0.8	2.1	6.6	1.5	16.9	0.1	23.2	0.9	4.8	4.2	1.3	1.7	1.3	1.9	0.4	0.2	1.5	0.8	0.0	3.9	3.5	6.0	4.5	0.6	1.6	6.2	4.3	2.7	5.0	4.6	8.2	5.3	14.0	2.8	2.1	5.4	4.9	2.5	9.6	9.1	2.6	8.9	2.2	3.2	0.2	12.7	4.4	0.3	0.3	9.1	6.3	4.0	5.8	4.9	5.7	4.5	10.1	7.5	7.2	1.9	10.0	15.5	2.7	1.3	4.3	2.3	4.3	5.2	2.2	2.1	2.6	6.3	3.1	5.7	6.1	6.3	5.9	1.9	2.9	7.2	2.9	5.1	5.4	0.1	0.2	0.2	0.3	0.2	0.1	0.9	0.4	0.2	0.2	1.3	0.6	0.8	0.4	1.5	0.2	1.9	0.4	0.0	0.6	0.6	0.6	0.6	0.6	0.7	0.7	0.5	0.8	0.1
BRIP1	"BACH1, FANCJ, OF"	ENSG00000136492	"BRCA1 interacting protein C-terminal helicase 1"	Q9BX63	17	61681266-61863521	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 30.1"	"Cell line enhanced"	"Detected in many"		"MCF7: 41.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"B-cells: 2.2;granulocytes: 2.1;T-cells: 3.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005474	Approved		Supported	"Nucleoplasm,Nuclear membrane"				"Nucleoplasm, Nuclear membrane"		"HPA005474: AB_2667333"	"unprognostic (1.88e-1)"	"unprognostic (1.55e-2)"	"prognostic favourable (3.45e-5)"	"unprognostic (6.85e-4)"	"unprognostic (3.09e-1)"	"prognostic favourable (3.62e-4)"	"unprognostic (2.60e-3)"	"unprognostic (5.60e-2)"	"unprognostic (5.66e-3)"	"unprognostic (6.71e-2)"	"unprognostic (1.50e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.41e-12)"	"unprognostic (1.19e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.62e-3)"	1.0	0.9	0.7	6.3	3.5	9.1	1.1	0.6	1.4	1.4	2.6	0.2	0.6	2.8	1.5	1.2	3.7	0.8	1.8	0.4	0.5	0.5	0.6	2.3	1.3	4.0	0.5	0.9	2.1	1.3	0.1	0.4	1.7	0.7	1.0	2.8	0.4	1.4	0.0	0.4	2.7	5.5	1.0	0.5	2.3	1.3	10.8	0.4	30.1	0.4	2.0	6.6	1.3	1.7	2.2	0.5	2.1	0.3	0.6	3.7	0.5	12.3	4.2	12.2	6.9	0.4	1.1	2.7	11.4	6.7	12.2	15.8	4.3	3.9	7.3	2.6	2.4	4.5	6.3	2.3	16.4	1.8	7.7	7.5	6.7	5.3	0.1	9.6	4.4	0.2	0.1	9.7	2.6	2.6	5.2	5.0	7.6	41.4	15.2	3.3	2.6	3.6	9.5	23.4	3.5	1.6	5.6	4.9	12.7	4.4	1.5	1.8	4.1	3.7	2.2	18.0	13.1	6.6	13.1	3.1	6.0	7.9	3.7	4.6	4.5	2.1	0.3	1.5	0.5	0.2	0.6	2.2	1.2	0.6	0.4	1.8	1.8	0.9	1.0	0.6	0.2	0.5	3.7	0.5	0.7	3.5	0.6	1.4	0.5	0.5	0.5	0.9	0.7	0.4
BUB1B	"Bub1A, BUBR1, MAD3L, SSK1"	ENSG00000156970	"BUB1 mitotic checkpoint serine/threonine kinase B"	O60566	15	40161023-40221136	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 49.5;testis: 25.6"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"naive B-cell: 2.8;plasmacytoid DC: 2.8"	"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			HPA008419			Supported	Cytosol				Cytosol		"HPA008419: AB_1078308"	"unprognostic (4.40e-2)"	"unprognostic (2.23e-1)"	"unprognostic (4.65e-2)"	"unprognostic (2.44e-3)"	"unprognostic (9.66e-2)"	"unprognostic (3.52e-2)"	"prognostic unfavourable (7.43e-6)"	"prognostic unfavourable (3.56e-4)"	"unprognostic (3.69e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavourable (1.79e-4)"	"unprognostic (1.76e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.75e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.20e-1)"	"unprognostic (3.94e-2)"	1.0	0.9	0.3	18.4	0.6	11.4	1.5	0.4	0.5	1.3	4.0	0.4	0.1	3.3	1.1	0.8	6.5	0.5	1.1	0.6	0.4	0.4	0.8	0.7	1.8	8.7	0.4	0.3	0.6	0.5	0.0	0.4	3.4	0.5	0.6	4.4	0.3	1.6	0.1	0.7	2.3	2.9	1.2	0.6	5.4	1.7	25.6	0.1	49.5	0.5	3.1	10.6	1.1	2.0	2.8	2.8	0.0	0.2	0.7	0.7	0.5	21.6	11.0	35.1	13.9	0.8	2.5	11.3	20.5	11.5	22.0	19.1	16.0	8.3	19.6	11.5	7.4	24.4	33.1	11.1	24.0	16.8	17.8	28.6	28.4	14.9	0.0	25.7	15.7	0.5	0.6	13.4	12.7	15.9	24.6	20.9	21.9	7.3	20.2	15.7	23.7	12.5	21.7	28.8	14.8	6.7	11.0	22.9	14.1	12.7	12.1	4.5	14.1	13.4	9.2	16.9	17.9	16.8	18.2	10.9	18.5	32.0	9.0	29.0	21.9	0.0	0.0	0.0	0.2	0.2	0.3	2.4	0.7	0.6	0.7	2.8	0.1	0.4	0.0	0.7	0.1	2.8	0.0	0.5	0.3	0.6	0.4	0.5	0.4	0.4	0.4	0.3	0.5	0.1
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121997-193253901	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016359, HPA030772"	Supported		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA030772: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"	23.4	20.0	18.1	16.8	22.9	21.0	20.1	25.6	22.6	20.4	20.1	14.5	16.3	12.0	26.8	15.2	20.6	14.9	16.4	21.4	18.4	15.0	18.8	17.1	17.2	16.6	19.7	15.9	23.3	14.5	27.1	24.8	17.3	19.4	26.9	16.2	13.6	17.3	19.0	44.5	15.0	14.5	25.6	23.9	16.0	15.7	16.3	22.1	20.6	27.1	14.1	15.8	26.8	35.0	6.6	6.7	10.2	7.0	9.0	12.5	5.2	13.3	12.0	15.9	10.2	14.9	14.5	12.2	14.4	14.0	17.4	15.3	8.2	15.9	17.4	10.2	17.7	13.1	14.4	13.6	21.3	11.0	6.8	12.6	10.9	8.0	14.0	17.1	12.6	11.8	13.2	16.3	15.6	14.8	19.1	14.1	23.3	12.3	13.9	8.5	15.3	4.5	12.5	9.6	16.6	20.4	9.3	4.8	13.1	18.0	22.2	20.5	19.1	12.4	16.5	17.0	3.9	14.4	14.7	13.2	9.8	14.3	10.2	10.5	29.6	6.6	7.0	10.2	9.3	6.8	12.5	6.6	9.2	9.2	6.7	5.4	8.4	8.7	7.4	9.0	5.7	4.9	9.3	5.2	18.1	22.9	25.6	22.6	18.4	15.0	19.7	15.9	19.4	22.1
CDH1	"CD324, UVO, uvomorulin"	ENSG00000039068	"Cadherin 1"	P12830	16	68737225-68835548	"Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Disease mutation, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 125.5"	"Cell line enhanced"	"Detected in some"		"BEWO: 105.6;CACO-2: 35.5;CAPAN-2: 49.6;HaCaT: 47.9;hTCEpi: 33.8;MCF7: 29.3;RT4: 36.5;T-47d: 31.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	12	"myeloid DC: 2.8;plasmacytoid DC: 8.5"	"Lineage enriched"	"Detected in single"	18	"dendritic cells: 8.5"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions"			22000000	"Plasma membrane, Cell Junctions"	"Golgi apparatus"	"CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: , CAB072856: , CAB072857: , HPA004812: AB_1078369"	"unprognostic (3.95e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.42e-1)"	"unprognostic (2.78e-1)"	"unprognostic (5.04e-3)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.19e-2)"	"unprognostic (3.61e-1)"	"prognostic favourable (2.06e-4)"	"unprognostic (1.21e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.51e-1)"	"unprognostic (5.92e-2)"	1.1	0.7	1.3	14.8	1.5	0.5	15.3	0.8	1.1	14.4	63.8	1.8	42.4	25.5	4.7	18.6	48.5	9.7	48.9	0.8	1.5	1.0	24.2	64.9	24.4	0.5	1.8	0.9	5.6	71.5	62.2	13.2	55.2	2.8	28.9	25.9	11.8	66.6	43.7	0.8	30.5	125.5	1.5	1.1	3.5	21.6	2.1	1.8	11.7	83.0	26.2	32.6	16.8	21.7	0.0	8.5	0.0	0.0	0.3	0.4	0.1	21.3	2.2	0.0	0.0	0.0	0.0	105.6	0.0	0.0	0.0	0.0	35.5	49.6	0.0	0.4	0.0	47.9	0.0	23.8	0.0	4.1	0.6	0.0	0.1	7.6	0.0	0.0	0.2	0.0	33.8	0.0	0.0	0.0	0.0	0.0	0.0	29.3	0.0	0.1	0.8	0.1	0.0	0.0	0.3	8.7	36.5	1.3	0.1	0.2	0.0	9.0	31.5	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.4	2.8	0.0	0.0	0.0	0.0	0.3	0.0	8.5	0.1	0.1	1.3	1.5	0.8	1.1	1.5	1.0	1.8	0.9	2.8	1.8
CDK4	PSK-J3	ENSG00000135446	"Cyclin dependent kinase 4"	P11802	12	57747727-57756013	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in all"	10	"HBEC3-KT: 125.1;LHCN-M2: 138.1;RH-30: 434.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006024, CAB013116, CAB069405"	Supported		Supported	"Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol"				Cytosol	"Nucleoplasm, Nuclear membrane, Nucleoli"	"CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: "	"unprognostic (8.88e-2)"	"unprognostic (2.53e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavourable (2.09e-7)"	"unprognostic (7.39e-2)"	"unprognostic (3.23e-3)"	"unprognostic (2.93e-2)"	"unprognostic (3.19e-2)"	"unprognostic (9.10e-2)"	"prognostic unfavourable (3.15e-5)"	"unprognostic (3.32e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.64e-1)"	"unprognostic (1.57e-2)"	32.2	43.1	13.8	22.2	15.7	24.0	45.0	13.1	17.9	36.3	28.2	20.1	22.8	15.2	51.4	28.1	29.9	31.0	32.3	27.4	14.5	12.1	24.0	36.9	26.8	26.4	18.3	13.7	61.4	54.4	18.9	34.2	25.0	16.0	37.2	26.9	26.2	29.3	24.1	27.8	25.6	20.7	34.1	13.5	27.2	23.9	24.6	17.5	29.2	54.3	32.1	27.5	33.6	30.9	29.6	25.5	2.6	19.9	15.8	32.1	22.2	9.3	10.8	14.3	12.7	13.1	11.5	9.5	5.4	17.6	23.8	19.8	15.4	8.9	13.6	9.7	8.4	7.2	19.7	125.1	18.1	6.7	9.1	12.7	7.3	10.8	15.4	14.4	8.8	11.3	9.2	14.6	16.8	15.3	13.5	11.7	138.1	13.5	13.7	11.7	16.8	11.0	12.4	434.6	12.6	7.4	14.7	12.9	12.1	9.5	7.2	14.4	9.6	17.5	6.9	11.2	10.5	12.6	10.9	5.8	9.5	20.9	10.3	13.3	13.4	1.7	14.3	2.6	26.2	19.9	27.0	29.6	23.1	23.7	21.0	28.1	32.1	28.5	1.2	15.8	12.0	25.5	16.6	22.2	13.8	15.7	13.1	17.9	14.5	12.1	18.3	13.7	16.0	17.5
CDKN1B	"KIP1, P27KIP1"	ENSG00000111276	"Cyclin dependent kinase inhibitor 1B"	P46527	12	12715058-12722371	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle"	"Protein kinase inhibitor"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003691, CAB021888, HPA059086"	Approved		Supported	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"CAB003691: AB_425362, CAB021888: , HPA059086: "	"unprognostic (5.67e-2)"	"unprognostic (9.76e-2)"	"prognostic favourable (5.15e-4)"	"unprognostic (6.90e-3)"	"unprognostic (5.84e-3)"	"unprognostic (1.03e-2)"	"prognostic unfavourable (3.25e-4)"	"unprognostic (4.04e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.85e-3)"	"unprognostic (9.23e-3)"	"unprognostic (2.96e-1)"	"prognostic unfavourable (8.39e-4)"	"unprognostic (1.23e-1)"	"unprognostic (8.68e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.15e-1)"	29.8	30.9	30.2	25.0	30.0	40.2	45.3	64.5	50.6	31.6	34.4	35.6	19.9	29.2	33.1	19.8	26.0	24.3	24.3	21.2	33.0	29.5	20.8	23.3	29.2	38.5	42.9	25.1	46.2	15.1	22.2	15.9	26.8	26.3	25.1	22.2	31.4	23.5	24.2	48.8	26.1	26.4	19.4	46.0	34.3	19.4	19.2	39.0	43.0	29.4	21.4	25.5	34.1	29.1	6.2	3.3	19.2	4.5	6.2	10.6	2.9	12.8	6.4	34.3	5.9	11.8	6.7	16.8	12.1	19.2	16.7	20.6	18.3	14.6	0.1	4.6	6.9	12.3	16.0	5.9	15.0	21.8	11.3	10.0	17.6	18.4	15.8	8.5	7.1	7.4	12.8	5.5	16.1	9.9	10.7	36.7	5.9	16.5	11.9	12.2	13.7	6.0	8.8	11.2	21.5	8.0	13.9	13.0	21.4	17.3	12.5	22.6	6.6	19.1	6.7	8.3	13.2	7.5	11.7	31.8	21.0	11.6	10.3	12.8	8.0	4.5	3.1	6.8	5.4	3.1	5.6	6.2	6.9	6.5	3.2	4.8	7.4	5.2	19.2	6.2	4.5	3.3	10.6	2.9	30.2	30.0	64.5	50.6	33.0	29.5	42.9	25.1	26.3	39.0
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967753-21995301	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 22.6;pituitary gland: 39.3"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 50.0;HEK 293: 56.7;HeLa: 53.1;SK-MEL-30: 53.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"T-reg: 22.6"	"Group enriched"	"Detected in many"	8	"B-cells: 7.2;T-cells: 22.6"					"Low region specificity"	"Detected in many"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli				Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: "	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavourable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favourable (5.19e-4)"	"prognostic unfavourable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavourable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	5.4	8.6	2.9	4.5	3.9	1.8	5.3	1.7	3.1	1.2	2.5	4.4	0.1	1.2	1.2	1.9	6.3	3.0	2.6	0.7	1.7	1.0	0.9	1.2	3.0	3.0	3.6	1.6	1.5	1.5	8.5	39.3	6.7	5.0	1.9	1.1	1.2	2.4	2.9	0.9	1.3	3.7	1.0	3.0	8.9	6.0	13.0	1.9	3.9	1.4	3.0	14.0	2.7	1.5	7.2	0.2	0.8	1.8	0.4	22.6	2.2	2.1	0.0	0.3	14.1	0.1	0.1	6.1	2.3	0.0	19.6	34.9	3.5	50.0	7.2	32.2	1.6	6.0	5.9	36.4	15.8	30.9	56.7	0.0	53.1	2.3	1.5	3.5	3.0	3.8	0.0	19.8	11.0	2.0	0.0	32.9	17.9	0.1	0.3	0.0	0.4	29.2	0.0	13.3	26.4	4.0	0.0	33.0	2.3	38.0	6.3	53.0	7.5	0.1	6.5	0.1	0.4	0.0	0.1	14.7	8.3	29.4	0.0	9.4	0.1	0.8	1.3	0.2	6.2	0.6	9.7	7.2	8.0	11.0	0.2	7.0	0.5	4.7	0.4	0.4	1.8	0.0	22.6	2.2	2.9	3.9	1.7	3.1	1.7	1.0	3.6	1.6	5.0	1.9
CHEK2	"bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53"	ENSG00000183765	"Checkpoint kinase 2"	O96017	22	28687743-28742422	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA001878, CAB002030"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus"				Nucleoplasm	"Golgi apparatus"	"CAB002030: AB_563660, HPA001878: AB_1078514"	"unprognostic (1.54e-1)"	"unprognostic (2.20e-1)"	"unprognostic (5.83e-2)"	"unprognostic (2.93e-2)"	"unprognostic (2.42e-1)"	"unprognostic (3.83e-2)"	"unprognostic (1.49e-3)"	"unprognostic (5.08e-3)"	"unprognostic (3.33e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.28e-2)"	"unprognostic (3.13e-1)"	"prognostic unfavourable (7.80e-9)"	"unprognostic (2.38e-2)"	"unprognostic (1.78e-1)"	"unprognostic (7.27e-2)"	"unprognostic (6.79e-3)"	5.6	8.3	2.5	13.0	7.0	13.7	5.6	0.7	5.6	6.6	9.8	2.5	4.8	6.8	4.8	10.9	10.0	4.3	6.0	6.0	4.1	2.3	5.3	6.5	7.9	10.1	6.7	1.6	12.9	6.7	1.2	4.2	10.1	5.1	8.3	10.6	8.7	7.0	5.8	2.2	6.3	8.5	5.4	5.0	9.8	5.8	9.7	3.6	13.1	7.5	4.8	13.7	6.2	6.7	11.8	8.7	6.5	8.4	2.9	4.4	3.7	14.7	4.7	13.5	16.7	3.8	19.2	8.7	7.3	8.6	9.7	14.2	12.0	10.1	17.4	6.2	5.1	14.2	20.5	13.4	11.3	12.4	15.7	22.9	9.0	19.8	3.8	14.5	16.8	8.1	6.2	12.4	11.0	10.7	13.8	15.2	9.0	20.7	11.6	23.3	19.0	12.0	25.3	9.2	20.3	6.0	6.1	7.9	4.5	8.1	14.5	8.0	9.9	13.4	3.7	7.8	9.3	6.8	3.8	9.2	16.2	34.0	7.4	15.2	9.9	6.5	3.7	1.2	1.1	8.4	2.3	11.8	2.2	2.1	8.7	8.4	4.4	2.8	0.3	2.9	4.1	7.0	2.8	3.7	2.5	7.0	0.7	5.6	4.1	2.3	6.7	1.6	5.1	3.6
CXCR4	"CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R"	ENSG00000121966	"C-X-C motif chemokine receptor 4"	P61073	2	136114349-136118165	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 149.9;lymphoid tissue: 186.3"	"Cell line enhanced"	"Detected in many"		"Daudi: 75.5;Karpas-707: 40.5;MOLT-4: 68.5;REH: 36.3;U-266/70: 87.9;U-698: 88.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"														"unprognostic (1.19e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.12e-2)"	"unprognostic (4.99e-2)"	"unprognostic (9.25e-2)"	"unprognostic (6.06e-2)"	"prognostic favourable (2.05e-4)"	"unprognostic (1.23e-1)"	"unprognostic (2.66e-1)"	"prognostic unfavourable (1.41e-7)"	"prognostic unfavourable (5.67e-4)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	"unprognostic (9.33e-2)"	15.4	26.5	3.0	39.1	3.4	149.9	9.7	0.8	2.1	7.7	8.7	6.8	1.5	1.6	8.3	3.8	16.4	9.1	12.0	5.4	4.1	4.7	8.2	7.1	29.3	94.5	6.5	1.3	6.3	3.1	0.7	8.1	7.8	6.1	6.8	7.0	10.0	10.6	2.2	3.2	2.3	57.8	3.8	22.9	82.4	8.0	7.2	3.4	186.3	9.2	4.6	97.5	50.0	6.6	47.3	16.8	37.8	7.2	4.0	32.0	11.9	0.1	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	75.5	0.2	0.0	0.0	0.2	0.0	0.0	3.8	0.9	4.5	12.0	0.0	0.0	10.4	8.2	0.0	0.0	0.0	0.0	7.2	0.1	40.5	0.0	0.2	68.5	9.3	1.2	0.3	36.3	8.4	13.2	0.6	0.0	4.2	3.5	0.0	0.2	0.0	0.0	20.5	1.0	0.0	0.2	0.0	0.0	87.9	14.8	88.4	0.0	17.2	0.0	17.9	7.2	29.6	22.9	3.8	18.7	30.1	21.1	21.7	6.6	47.3	32.0	30.1	37.8	4.0	2.1	16.8	18.9	11.9	3.0	3.4	0.8	2.1	4.1	4.7	6.5	1.3	6.1	3.4
CYLD	"CYLD1, KIAA0849, USPL2"	ENSG00000083799	"CYLD lysine 63 deubiquitinase"	Q9NQC7	16	50742050-50801935	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 46.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011713, HPA050095"	Approved		Supported	"Nucleoplasm,Centriolar satellite"				"Centriolar satellite"	Nucleoplasm	"CAB011713: AB_731794, HPA050095: "	"unprognostic (9.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (5.01e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.84e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.87e-2)"	"unprognostic (3.24e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.18e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (8.42e-2)"	9.3	16.2	13.9	22.9	26.4	51.1	9.1	14.2	20.9	9.2	10.3	18.8	12.8	10.2	16.1	8.1	15.3	8.5	13.3	12.7	15.7	17.0	9.4	13.2	15.6	30.7	16.3	14.3	11.5	12.2	20.3	27.8	9.8	20.0	11.0	12.7	13.3	12.6	10.9	31.7	12.4	14.2	12.5	16.3	23.4	12.4	22.6	13.7	16.9	16.2	8.0	29.3	14.1	12.6	9.2	10.2	31.4	9.8	13.6	19.1	10.2	9.1	2.9	3.3	3.7	5.3	7.7	3.0	13.6	19.9	14.2	8.4	2.4	4.3	10.6	4.9	13.2	3.6	3.9	8.2	21.1	46.4	6.0	5.3	5.1	1.9	10.6	5.2	24.9	8.4	6.7	17.1	17.9	5.7	2.2	9.2	19.8	1.3	5.1	7.6	3.5	4.8	4.6	6.8	10.1	4.6	3.2	4.3	3.3	11.5	3.9	3.3	3.9	6.6	6.4	24.3	5.5	8.5	5.5	24.3	23.1	11.8	17.8	5.9	5.1	31.4	8.6	20.8	10.7	9.8	12.9	9.2	15.8	14.4	10.2	6.2	14.7	11.4	19.4	13.6	9.5	6.2	19.1	10.2	13.9	26.4	14.2	20.9	15.7	17.0	16.3	14.3	20.0	13.7
DDB2	"DDBB, FLJ34321, UV-DDB2, XPE"	ENSG00000134574	"Damage specific DNA binding protein 2"	Q92466	11	47214465-47239240	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB025912, HPA058406"	Enhanced		Supported	"Nucleoplasm,Cell Junctions"				"Nucleoplasm, Cell Junctions"		"CAB025912: , HPA058406: "	"prognostic favourable (7.29e-4)"	"prognostic favourable (1.58e-4)"	"unprognostic (1.49e-1)"	"prognostic favourable (1.20e-4)"	"unprognostic (4.29e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.58e-3)"	"unprognostic (3.53e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.21e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.82e-3)"	"unprognostic (1.07e-1)"	12.2	22.2	5.3	13.3	8.6	8.1	11.3	11.0	8.2	16.8	13.5	7.3	13.4	6.0	18.2	14.1	25.4	14.3	13.0	6.1	4.7	2.9	6.6	20.8	11.3	16.1	15.0	5.0	9.8	15.6	6.1	8.6	5.5	6.3	20.9	12.3	8.1	17.6	14.8	6.3	36.9	11.0	19.0	17.6	15.1	9.1	7.6	7.6	23.3	6.6	16.7	26.0	17.3	15.2	11.4	6.1	11.5	11.0	7.4	27.0	9.0	8.2	22.3	9.3	7.0	6.0	12.2	11.0	9.1	21.3	11.6	13.7	3.6	4.8	19.9	1.9	8.3	14.6	5.3	18.5	5.8	4.9	10.0	4.7	21.3	16.5	5.9	5.4	12.4	16.3	21.0	5.8	13.0	34.0	1.2	9.7	19.0	15.6	20.7	2.6	3.0	8.1	10.4	2.3	10.7	4.9	8.2	4.9	6.1	11.1	3.2	2.9	20.4	1.8	14.6	35.7	16.3	7.8	4.2	10.2	7.7	4.4	13.4	6.9	12.8	5.9	8.1	11.5	12.1	11.0	11.7	11.4	12.7	11.7	6.1	7.4	9.4	10.1	2.2	7.4	9.2	0.1	27.0	9.0	5.3	8.6	11.0	8.2	4.7	2.9	15.0	5.0	6.3	7.6
DICER1	"Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1"	ENSG00000100697	"Dicer 1, ribonuclease III"	Q9UPY3	14	95086228-95158010	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"RNA-mediated gene silencing"	"Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000694, CAB068185"	Approved		Supported	Cytosol				Cytosol		"CAB068185: , HPA000694: AB_1078661"	"unprognostic (2.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.72e-1)"	"unprognostic (6.75e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.52e-3)"	"unprognostic (5.73e-2)"	"unprognostic (9.22e-2)"	"unprognostic (4.22e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.04e-3)"	"unprognostic (3.74e-2)"	23.2	12.5	18.4	22.4	33.3	20.5	23.2	28.5	29.9	19.0	18.1	31.4	22.4	13.0	20.8	20.6	23.4	18.5	16.2	15.3	22.0	14.1	19.5	23.6	22.4	20.3	29.7	19.6	23.8	19.8	26.9	30.9	29.9	23.2	20.3	19.7	14.5	19.5	18.9	28.0	20.7	17.3	19.0	26.8	20.7	17.1	20.6	32.0	17.0	23.8	14.7	20.3	20.7	24.1	2.5	1.8	10.7	7.2	1.2	3.3	1.0	12.8	13.4	25.1	9.3	6.5	9.8	19.9	10.6	6.4	6.8	8.2	17.0	9.9	14.5	11.5	9.8	15.2	19.9	10.0	14.2	22.5	8.9	21.9	7.4	12.2	6.6	13.4	13.5	9.1	8.3	9.1	13.9	10.1	9.2	12.9	11.4	18.0	15.0	8.9	7.1	6.6	12.0	20.5	8.0	9.0	20.5	20.8	11.8	10.7	11.0	12.0	12.4	9.9	10.0	5.2	10.3	10.1	11.9	14.8	21.1	20.6	5.4	10.9	9.3	3.1	3.0	1.2	1.6	3.1	3.3	1.9	1.5	1.2	1.8	2.5	1.5	1.3	10.7	1.2	7.2	1.6	1.6	1.0	18.4	33.3	28.5	29.9	22.0	14.1	29.7	19.6	23.2	32.0
EGFR	"ERBB, ERBB1"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019021-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 102.3"	"Cell line enriched"	"Detected in many"	12	"A-431: 337.7"	"Cancer enhanced"	"Detected in all"		"glioma: 136.0"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534"	Enhanced		Enhanced	"Plasma membrane,Cell Junctions"	"Secreted to blood"		93000000	"Plasma membrane, Cell Junctions"		"CAB000035: , CAB068186: , CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044"	"unprognostic (2.62e-2)"	"unprognostic (9.56e-3)"	"unprognostic (1.59e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.27e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.88e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.30e-3)"	"unprognostic (1.78e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.93e-3)"	"unprognostic (6.98e-3)"	"unprognostic (1.72e-1)"	"unprognostic (6.62e-2)"	"prognostic unfavourable (2.04e-5)"	16.2	8.4	4.9	7.5	6.8	0.1	39.8	5.1	8.5	13.8	7.8	3.3	10.7	3.6	8.2	11.7	15.6	8.8	8.5	4.8	6.8	2.7	7.6	23.5	14.2	2.3	4.1	3.9	10.4	10.1	1.8	2.1	102.3	5.6	10.9	6.7	9.2	15.4	12.9	10.7	32.5	6.3	15.5	3.5	3.3	7.8	5.5	5.9	3.2	12.8	15.5	8.0	10.2	28.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	337.7	4.3	1.1	1.5	6.9	4.3	1.1	3.3	4.5	2.0	1.6	0.8	3.7	0.2	0.8	2.8	13.5	0.0	14.9	2.5	0.1	0.2	0.0	1.8	0.2	1.8	0.0	0.0	2.1	13.7	5.2	27.9	0.2	0.0	0.0	4.4	0.2	0.0	0.0	0.3	2.2	0.0	0.6	0.0	2.5	3.6	0.0	1.3	2.8	3.4	0.6	0.3	0.7	1.0	1.9	0.5	14.6	3.1	0.0	0.3	0.1	2.5	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.9	6.8	5.1	6.6	6.8	2.7	4.1	3.9	5.6	5.9
ERBB4	"ALS19, HER4"	ENSG00000178568	"Erb-b2 receptor tyrosine kinase 4"	Q15303	2	211375717-212538841	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Lactation, Transcription, Transcription regulation"	"Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"fallopian tube: 24.5"	"Cell line enhanced"	"Detected in some"		"AF22: 9.4;EFO-21: 7.0;HEK 293: 5.2;RPTEC TERT1: 7.7;SCLC-21H: 4.3;T-47d: 6.9"	"Cancer enhanced"	"Detected in many"		"breast cancer: 4.1"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000276, HPA012016, CAB025522"	Enhanced						140000			"CAB000276: , CAB025522: , HPA012016: AB_1846541"	"unprognostic (1.48e-1)"	"unprognostic (3.28e-1)"	"unprognostic (4.31e-3)"	"unprognostic (1.76e-3)"	"unprognostic (3.59e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.88e-1)"	"unprognostic (9.56e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.67e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.61e-1)"	"unprognostic (7.14e-3)"	"unprognostic (1.49e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (4.11e-2)"	1.6	1.9	15.1	1.2	15.0	1.0	13.4	18.6	14.1	7.8	1.1	7.6	8.8	1.1	1.5	1.2	1.3	24.5	1.2	7.0	14.3	6.5	11.9	1.1	2.9	1.2	7.8	10.7	1.3	2.4	10.8	5.1	1.3	8.8	1.7	1.1	2.0	9.7	18.1	3.8	1.8	1.2	1.1	7.3	1.2	1.5	7.6	12.0	0.0	4.5	1.1	1.2	1.4	0.7	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	9.4	0.2	0.0	0.0	0.0	0.0	0.3	0.5	0.1	0.0	0.0	0.0	7.0	1.0	0.4	0.2	0.0	0.0	0.1	5.2	0.0	1.7	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	7.7	0.4	4.3	0.2	0.0	0.1	0.1	6.9	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.1	15.0	18.6	14.1	14.3	6.5	7.8	10.7	8.8	12.0
ERCC2	"EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD"	ENSG00000104884	"ERCC excision repair 2, TFIIH core complex helicase subunit"	P18074	19	45349837-45370918	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005375, HPA038057, HPA069266"	Approved		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB005375: AB_2100152, HPA038057: , HPA069266: "	"unprognostic (1.10e-1)"	"unprognostic (5.48e-1)"	"unprognostic (5.08e-2)"	"unprognostic (9.92e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.41e-1)"	"unprognostic (1.06e-1)"	"prognostic favourable (3.26e-4)"	"unprognostic (3.36e-2)"	"unprognostic (2.44e-3)"	"unprognostic (1.94e-1)"	"unprognostic (5.47e-1)"	"unprognostic (8.99e-2)"	"unprognostic (3.45e-2)"	7.4	15.6	11.4	10.6	17.7	6.7	7.1	9.5	23.8	9.4	8.1	11.7	7.8	7.9	11.7	6.0	6.7	10.0	10.1	7.9	9.4	9.1	8.7	13.2	6.5	9.9	8.2	10.5	9.5	13.1	12.9	10.9	7.2	14.0	8.2	6.4	12.5	9.5	11.8	15.9	10.7	7.1	11.2	5.3	9.7	8.3	17.2	7.8	10.8	10.2	5.1	8.3	9.3	6.6	7.8	17.2	5.0	13.9	11.3	9.8	8.7	12.3	6.0	12.6	17.7	7.5	8.9	6.7	17.6	12.1	22.8	17.5	14.0	8.5	4.4	10.1	17.1	6.4	8.8	14.8	8.7	10.6	14.5	7.5	11.5	14.7	15.9	11.9	13.3	10.2	2.3	26.0	14.8	13.2	18.2	5.0	15.7	6.0	7.0	7.9	5.8	10.6	13.5	8.9	3.7	6.5	10.9	7.4	8.0	15.6	11.1	6.2	10.5	15.8	17.1	21.8	11.9	9.2	39.1	11.6	6.7	6.4	6.4	7.3	9.6	0.0	13.3	5.0	7.7	13.9	9.8	7.8	7.4	7.4	17.2	5.8	7.1	7.4	0.4	11.3	10.9	8.3	7.4	8.7	11.4	17.7	9.5	23.8	9.4	9.1	8.2	10.5	14.0	7.8
ERCC3	"BTF2, GTF2H, RAD25, TFIIH, XPB"	ENSG00000163161	"ERCC excision repair 3, TFIIH core complex helicase subunit"	P19447	2	127257290-127294176	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037153, HPA046077"	Approved		Enhanced	Nucleoplasm				Nucleoplasm		"CAB037153: AB_796181, HPA046077: "	"unprognostic (2.31e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.07e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.85e-2)"	"prognostic unfavourable (1.62e-7)"	"unprognostic (2.74e-1)"	"unprognostic (9.13e-3)"	"unprognostic (9.25e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.46e-2)"	"prognostic unfavourable (4.30e-6)"	"unprognostic (3.71e-1)"	"unprognostic (8.50e-2)"	"unprognostic (5.73e-2)"	"unprognostic (3.92e-2)"	17.4	20.0	26.1	23.8	28.9	20.5	21.0	35.9	32.0	22.1	19.4	19.7	17.1	11.5	21.6	15.7	19.1	23.6	20.4	20.4	23.2	18.8	17.5	17.4	19.4	23.1	19.7	25.8	23.3	22.4	32.0	26.4	16.3	21.5	20.1	17.1	18.3	18.0	21.8	30.1	19.7	17.3	26.1	16.0	24.5	17.4	39.5	20.1	24.1	19.3	15.8	25.9	22.4	20.8	11.8	13.9	7.2	9.7	18.8	16.2	11.7	21.8	15.1	18.6	19.7	20.8	14.2	23.1	20.1	26.2	32.6	31.6	22.9	16.0	16.6	16.7	18.3	19.6	28.4	21.2	28.4	25.9	25.4	20.8	18.4	24.2	15.4	18.1	22.7	14.7	19.9	37.7	16.1	20.9	20.2	10.9	20.5	21.6	25.7	19.5	27.1	23.5	21.2	21.4	13.7	18.2	20.4	22.6	24.4	17.2	26.2	26.3	14.1	20.8	16.6	19.6	22.5	17.8	23.9	19.5	38.1	26.0	17.3	8.7	20.9	6.6	9.5	7.2	16.0	9.7	16.2	11.5	11.8	13.5	13.9	11.8	15.8	10.9	3.1	18.8	7.9	11.3	16.1	11.7	26.1	28.9	35.9	32.0	23.2	18.8	19.7	25.8	21.5	20.1
ERCC4	"FANCQ, RAD1, XPF"	ENSG00000175595	"ERCC excision repair 4, endonuclease catalytic subunit"	Q92889	16	13920157-13952345	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Disease mutation, Dwarfism, Fanconi anemia, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000156, HPA045828"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Cell Junctions"				"Nucleoplasm, Nuclear bodies"	"Cell Junctions"	"CAB000156: , HPA045828: "	"unprognostic (2.05e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.12e-3)"	"unprognostic (9.41e-2)"	"unprognostic (3.35e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.59e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.49e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.15e-1)"	"unprognostic (6.30e-2)"	"unprognostic (5.88e-4)"	8.4	12.7	8.6	7.0	11.3	5.3	6.4	8.9	9.7	8.1	6.7	9.9	6.0	4.1	8.5	6.8	6.7	8.5	6.8	7.8	7.2	7.1	6.9	7.2	6.9	6.8	10.5	8.8	9.9	7.6	13.3	13.0	5.9	9.6	8.3	5.4	7.1	6.4	7.0	31.3	6.9	5.7	8.5	10.3	7.7	6.6	14.2	8.9	13.7	9.7	5.6	6.4	9.1	7.8	8.4	7.9	8.3	6.8	8.9	7.4	2.6	5.4	7.0	6.4	9.2	10.7	10.1	5.0	7.2	7.7	6.5	8.3	2.4	5.4	9.1	10.4	6.3	6.9	9.5	4.9	10.1	12.3	5.6	4.5	7.8	6.0	9.8	6.0	5.1	7.6	6.9	8.6	7.3	8.6	7.0	10.7	9.1	4.5	8.0	4.1	4.7	3.7	9.2	13.0	11.2	4.0	3.7	5.3	6.3	8.8	7.2	6.7	9.1	4.6	9.7	9.6	7.1	8.6	6.3	9.5	11.1	6.3	9.2	7.3	9.7	8.3	6.2	5.4	6.8	6.8	7.4	6.2	6.4	5.1	5.5	8.4	6.4	6.9	7.2	8.9	5.7	7.9	5.8	2.6	8.6	11.3	8.9	9.7	7.2	7.1	10.5	8.8	9.6	8.9
ERCC5	"ERCM2, XPGC"	ENSG00000134899	"ERCC excision repair 5, endonuclease"	P28715	13	102807146-102876001	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA045845, HPA050126, HPA050374"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"HPA045845: , HPA050126: , HPA050374: "	"unprognostic (1.28e-3)"	"unprognostic (1.32e-3)"	"unprognostic (1.86e-2)"	"unprognostic (9.28e-3)"	"unprognostic (6.19e-2)"	"unprognostic (8.73e-2)"	"unprognostic (1.23e-1)"	"unprognostic (8.72e-2)"	"unprognostic (2.52e-1)"	"unprognostic (2.55e-1)"	"unprognostic (7.77e-3)"	"unprognostic (5.76e-3)"	"prognostic unfavourable (2.96e-6)"	"unprognostic (3.56e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.67e-1)"	"prognostic favourable (6.82e-4)"	22.3	19.1	15.9	16.1	17.8	23.7	20.1	26.4	20.8	19.7	27.0	17.9	27.0	25.0	22.1	25.7	21.0	15.1	21.1	15.4	14.6	13.1	18.7	28.1	19.9	26.4	17.1	16.2	22.9	22.3	15.7	25.6	17.9	19.0	20.1	23.1	15.9	20.5	24.7	14.6	25.8	31.1	17.0	19.4	30.6	21.9	14.0	17.8	40.8	21.8	16.6	26.0	22.4	19.6	10.1	10.8	23.4	17.4	17.7	17.5	12.0	14.7	5.4	10.8	6.7	21.5	20.2	6.5	14.9	19.9	8.7	11.3	8.2	20.6	9.3	7.5	15.1	15.4	9.5	13.7	9.1	14.0	5.3	13.8	15.6	7.2	10.5	28.0	18.0	19.2	13.2	10.0	15.6	15.1	6.4	8.5	15.2	4.0	15.1	19.5	4.6	7.5	8.2	8.0	9.3	17.9	8.2	7.2	10.7	7.8	13.2	8.0	11.8	26.2	15.2	6.7	3.4	5.6	9.4	12.4	3.7	4.7	26.2	11.4	8.4	23.4	9.8	18.3	16.7	12.3	15.5	9.6	15.5	17.5	10.8	10.1	16.6	16.1	7.2	17.7	17.4	7.7	16.6	12.0	15.9	17.8	26.4	20.8	14.6	13.1	17.1	16.2	19.0	17.8
EXT1	"LGCR, LGS, ttv"	ENSG00000182197	"Exostosin glycosyltransferase 1"	Q16394	8	117794490-118111853	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Hereditary multiple exostoses, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 66.4"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 55.1;fHDF/TERT166: 55.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044394	Uncertain						9600000			"HPA044394: AB_10963838"	"unprognostic (1.29e-2)"	"prognostic unfavourable (7.04e-4)"	"unprognostic (2.73e-2)"	"unprognostic (2.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (7.55e-2)"	"unprognostic (1.99e-1)"	"prognostic unfavourable (1.20e-5)"	"unprognostic (1.70e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.31e-2)"	"unprognostic (6.58e-2)"	"unprognostic (1.27e-2)"	"unprognostic (9.84e-2)"	"unprognostic (9.49e-2)"	"prognostic unfavourable (4.64e-4)"	"unprognostic (1.85e-1)"	13.8	11.9	5.8	20.5	4.6	2.1	16.5	7.3	7.4	13.3	17.1	4.1	8.7	23.2	11.5	12.5	11.2	8.8	19.3	14.4	4.6	3.1	8.8	66.4	19.9	8.3	3.0	6.8	10.4	17.9	7.1	6.4	15.6	4.8	9.8	16.0	13.2	9.8	13.3	4.2	12.3	32.0	16.8	4.3	20.1	11.5	5.0	2.7	8.7	12.0	10.3	7.2	11.0	18.5	0.8	1.7	1.2	4.5	0.7	2.4	1.0	17.2	5.0	7.5	2.9	13.6	11.0	3.4	32.3	55.1	23.8	21.9	5.1	1.7	0.3	14.5	55.7	10.9	3.3	18.9	33.5	6.5	5.6	0.6	4.7	4.1	6.4	0.0	1.2	6.9	5.1	28.9	26.6	14.6	0.4	4.8	11.0	1.4	0.8	0.0	2.4	6.4	0.0	2.8	0.5	9.4	6.3	2.3	2.2	4.9	2.3	4.8	3.2	0.2	19.4	20.1	18.4	18.4	9.5	2.7	2.7	1.6	18.6	0.0	5.3	0.3	4.4	0.2	0.2	4.5	1.3	0.8	0.5	0.6	1.0	0.1	0.5	0.9	1.2	0.7	2.2	1.7	2.4	1.0	5.8	4.6	7.3	7.4	4.6	3.1	3.0	6.8	4.8	2.7
EXT2	SOTV	ENSG00000151348	"Exostosin glycosyltransferase 2"	Q93063	11	44095549-44245429	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078409			Supported	"Golgi apparatus"			20000000	"Golgi apparatus"		"HPA078409: "	"unprognostic (5.87e-2)"	"unprognostic (3.05e-3)"	"unprognostic (3.48e-2)"	"unprognostic (3.94e-1)"	"unprognostic (1.42e-1)"	"prognostic unfavourable (2.50e-4)"	"unprognostic (1.77e-3)"	"unprognostic (2.22e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.70e-2)"	"prognostic unfavourable (5.36e-6)"	"unprognostic (7.07e-3)"	"unprognostic (2.97e-1)"	"unprognostic (3.85e-1)"	"unprognostic (1.36e-2)"	24.5	19.5	11.6	17.2	18.5	6.6	25.8	14.5	23.0	26.8	25.0	15.5	17.5	17.6	37.1	25.5	16.7	26.0	23.4	22.7	11.7	13.0	19.2	36.3	22.3	16.8	11.8	12.3	29.3	21.8	25.7	17.3	58.0	16.2	23.7	20.6	22.9	24.7	22.8	16.9	20.2	34.0	35.0	12.2	18.7	19.3	20.0	11.4	16.2	24.7	16.7	13.0	20.2	23.2	6.7	14.9	13.0	12.0	17.8	17.6	9.8	12.9	17.9	9.7	30.2	44.8	33.0	13.4	40.2	50.3	23.8	32.4	12.7	8.9	8.9	18.3	47.0	20.6	10.4	28.5	28.8	17.9	14.3	8.2	9.4	9.7	17.7	8.2	17.8	25.6	18.9	14.4	22.5	33.8	11.0	16.2	17.3	9.9	5.7	5.0	10.4	12.8	7.2	27.8	4.5	13.7	12.3	7.0	7.8	25.4	10.4	6.7	17.3	8.8	30.5	32.2	21.1	31.5	25.7	7.3	9.5	6.5	21.2	6.4	34.3	9.3	11.9	13.0	15.6	12.0	17.6	6.4	12.5	14.4	14.9	6.7	11.9	11.7	2.6	17.8	8.5	5.1	9.6	9.8	11.6	18.5	14.5	23.0	11.7	13.0	11.8	12.3	16.2	11.4
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"Fanconi anemia complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 20.6;testis: 28.8"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm				Nucleoplasm		"HPA063236: "	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"	2.1	2.0	2.2	16.5	3.7	17.1	1.7	5.7	6.6	1.7	5.1	1.1	0.6	5.0	1.7	3.1	6.6	1.9	1.6	1.7	1.8	1.4	2.1	5.8	3.3	11.1	1.3	2.7	1.6	1.8	2.3	1.9	11.2	2.4	1.7	6.3	1.5	2.2	0.5	0.7	5.0	5.4	2.0	1.6	6.9	3.5	28.8	0.8	20.6	1.7	4.6	17.6	2.9	2.5	7.4	6.5	9.9	9.2	7.5	9.5	4.2	9.2	14.2	17.0	14.9	1.1	2.2	13.0	11.5	6.3	19.5	8.2	12.4	15.4	22.7	5.4	3.9	14.2	11.4	8.6	20.6	5.3	19.2	6.7	18.2	25.4	0.7	6.8	7.4	0.7	0.9	15.8	5.0	6.1	16.1	7.0	10.1	21.4	13.6	29.5	11.0	8.9	24.8	13.7	4.1	4.8	8.7	15.3	8.3	17.2	5.1	2.2	9.3	12.3	4.5	15.7	16.5	8.7	12.0	6.3	7.3	22.6	7.4	15.3	14.8	2.6	7.9	9.9	4.7	8.8	3.3	7.4	2.8	4.1	6.5	5.5	0.7	3.0	9.8	7.5	9.2	0.4	9.5	4.2	2.2	3.7	5.7	6.6	1.8	1.4	1.3	2.7	2.4	0.8
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"Fanconi anemia complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 29.7"	"Cell line enhanced"	"Detected in all"		"RH-30: 31.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	6	"basophil: 10.4"	"Lineage enriched"	"Detected in many"	6	"granulocytes: 10.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm				Nucleoplasm		"CAB017793: , HPA030771: "	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favourable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"	4.9	2.7	4.3	8.6	7.0	3.6	4.6	29.7	7.7	4.6	6.4	4.9	5.1	7.1	6.3	4.1	4.5	3.6	5.2	3.2	4.0	2.7	10.0	25.7	6.7	3.7	7.3	1.6	3.3	5.4	2.9	12.1	4.3	6.7	4.4	6.1	4.0	4.0	4.2	4.5	7.7	8.1	2.9	6.4	3.4	4.4	19.6	7.3	7.9	4.3	3.2	6.0	3.5	4.0	1.0	1.3	10.4	1.7	0.3	1.5	0.7	13.4	9.1	12.0	10.5	1.2	3.2	7.6	5.9	3.8	9.4	8.7	10.4	5.7	7.7	4.1	4.3	16.5	12.2	5.1	5.1	7.3	5.7	6.0	10.2	5.3	2.0	6.0	6.8	2.7	2.1	7.5	3.3	5.2	9.0	3.4	6.7	9.5	5.6	3.5	5.8	5.2	12.1	31.2	3.6	3.9	3.5	17.5	9.3	11.1	4.0	3.4	4.1	5.1	2.5	8.3	12.0	9.0	8.3	3.5	6.5	4.0	4.4	5.5	9.7	10.4	0.4	0.0	1.3	0.8	1.3	1.0	0.7	1.5	0.4	1.0	1.2	1.0	0.1	0.3	1.7	1.3	1.3	0.7	4.3	7.0	29.7	7.7	4.0	2.7	7.3	1.6	6.7	7.3
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"Fanconi anemia complementation group D2"	Q9BXW9	3	10026414-10101930	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 24.4;testis: 23.3"	"Cell line enhanced"	"Detected in many"		"BEWO: 45.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"				Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: "	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavourable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"	2.0	1.3	0.8	10.3	2.6	12.2	2.4	1.6	2.7	1.7	2.9	1.1	1.0	2.2	2.2	1.8	4.7	2.4	2.5	1.1	0.8	0.9	2.3	1.0	2.4	9.5	1.3	1.2	3.5	3.5	0.6	1.1	5.3	1.4	2.2	4.9	1.6	3.3	0.4	3.0	3.3	6.2	1.2	2.0	7.3	2.4	23.3	1.6	24.4	1.6	5.6	14.6	2.2	2.4	6.8	3.7	5.3	2.6	2.1	2.9	1.0	8.5	9.1	17.5	4.9	0.9	1.3	45.3	7.9	3.5	11.4	9.3	6.8	8.5	16.8	3.7	2.6	7.5	18.0	6.1	11.4	8.0	12.2	23.0	14.0	6.5	0.1	17.0	14.4	0.4	1.0	12.8	7.1	6.8	14.0	19.3	8.5	9.9	14.2	6.5	21.1	6.4	15.5	14.2	11.9	3.9	9.7	4.9	9.6	9.7	7.6	3.1	11.6	10.8	3.9	9.4	10.8	5.7	11.4	8.2	16.0	28.5	5.4	17.5	16.1	5.3	1.4	3.7	1.5	1.0	1.3	4.9	2.0	1.2	0.9	6.8	2.5	1.9	3.3	2.1	2.6	3.7	2.9	1.0	0.8	2.6	1.6	2.7	0.8	0.9	1.3	1.2	1.4	1.6
FANCE	"FACE, FAE"	ENSG00000112039	"Fanconi anemia complementation group E"	Q9HB96	6	35452361-35467103	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"											CAB014893	Enhanced		Supported	Nucleoplasm				Nucleoplasm		"CAB014893: "	"unprognostic (2.66e-1)"	"unprognostic (8.01e-3)"	"unprognostic (7.73e-2)"	"prognostic unfavourable (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.80e-3)"	"prognostic unfavourable (2.08e-9)"	"unprognostic (8.90e-2)"	"unprognostic (5.70e-3)"	"unprognostic (8.41e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.91e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.05e-1)"	"unprognostic (2.44e-2)"	"unprognostic (5.14e-2)"	7.2	2.1	2.6	7.0	3.8	7.2	8.5	5.5	3.9	6.7	4.1	4.8	1.5	3.1	6.1	4.7	10.0	4.9	5.4	4.1	2.8	3.2	2.4	1.7	5.5	5.4	2.4	1.8	10.8	6.9	2.7	4.0	21.3	3.9	6.7	4.1	3.7	5.3	4.0	20.8	16.8	4.7	4.1	3.7	4.6	3.8	12.1	3.5	3.0	5.9	10.1	8.5	6.7	15.0	2.4	1.8	1.0	1.0	2.6	3.6	0.9	5.6	2.8	7.7	17.3	5.6	10.0	20.7	6.8	5.8	8.9	7.8	6.6	3.2	19.3	4.5	4.2	4.2	8.6	5.8	8.6	6.5	7.5	13.5	6.7	4.3	3.0	7.9	5.5	6.3	17.5	10.9	16.8	5.2	12.4	7.2	7.4	6.6	3.7	9.9	3.2	4.4	10.9	7.3	7.2	2.0	6.2	7.7	7.2	3.9	5.5	6.1	5.4	25.8	3.2	10.8	9.0	6.9	10.6	4.8	16.6	7.0	2.4	14.6	10.1	0.7	1.0	1.0	2.2	0.6	3.0	0.7	2.8	3.6	0.6	2.4	1.9	1.9	0.6	2.6	0.6	1.8	1.7	0.9	2.6	3.8	5.5	3.9	2.8	3.2	2.4	1.8	3.9	3.5
FANCF	FAF	ENSG00000183161	"Fanconi anemia complementation group F"	Q9NPI8	11	22622519-22626787	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 15.2"	"Cell line enhanced"	"Detected in many"		"SCLC-21H: 20.9"	"Low cancer specificity"	"Detected in all"							"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA008899			Supported	Nucleoplasm				Nucleoplasm		"HPA008899: "	"unprognostic (1.16e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.55e-2)"	"unprognostic (8.84e-2)"	"prognostic unfavourable (2.27e-4)"	"unprognostic (4.29e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.74e-3)"	"unprognostic (3.95e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.81e-1)"	"unprognostic (9.14e-2)"	"unprognostic (7.64e-3)"	1.2	4.1	2.9	3.1	2.8	1.1	3.2	1.0	2.7	3.1	3.4			5.3	3.0	6.0	3.0	6.1	1.7	1.9	2.9	3.9	3.2	4.2	1.8	4.9	3.3		4.2	9.0	3.4	4.5	1.5		2.9	3.7		3.8	3.1	0.4	3.1	4.9	1.1	3.5	5.4	4.6	4.3			3.6		4.8	2.6	2.0	15.2	9.7	11.5	5.7	10.0	15.1	7.3	1.4	4.3	5.6	6.1	2.9	3.5	2.3	2.8	3.3	3.2	3.5	2.8	2.2	7.2	0.7	2.8	6.2	4.5	4.6	1.6	11.7	2.1	2.7	1.8	4.9	3.4	4.9	2.9	3.4	9.0	1.1	4.9	5.0	6.8	9.4	2.0	4.5	12.5	4.6	6.4	5.4	10.9	2.6	8.0	6.0	5.6	20.9	9.8	1.5	4.9	4.8	9.9	4.5	3.6	3.3	3.5	5.9	4.0	5.4	6.9	2.1	5.4	2.0	7.6	5.7	5.4	11.5	11.5	5.5	13.5	11.8	10.8	10.8	6.4	15.2	15.1	12.4	0.8	10.0	5.7	9.7	7.3	7.3										
FANCG	"FAG, XRCC9"	ENSG00000221829	"Fanconi anemia complementation group G"	O15287	9	35073835-35080016	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008105, HPA045335"	Approved		Supported	"Nucleoli,Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"	Nucleoli	"CAB008105: AB_2231542, HPA045335: "	"unprognostic (9.41e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.83e-3)"	"prognostic unfavourable (2.02e-4)"	"unprognostic (8.92e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.27e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.62e-2)"	"prognostic unfavourable (2.38e-7)"	"unprognostic (1.14e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.10e-1)"	5.8	5.0	4.4	7.1	6.5	14.9	7.5	13.9	8.5	6.2	5.9	5.3	8.4	6.7	6.8	3.2	9.2	8.6	4.7	5.9	7.6	4.0	5.2	4.5	5.1	9.9	8.7	4.4	9.2	17.0	6.7	4.8	7.6	6.6	7.0	5.5	3.5	8.7	9.7	2.9	8.9	6.5	6.4	4.2	8.6	5.8	8.9	7.6	25.6	9.3	4.8	9.2	6.8	6.9	6.8	4.8	8.9	2.5	8.8	9.2	3.4	15.7	19.5	14.3	13.2	3.2	5.1	12.0	11.1	8.0	21.8	20.9	9.3	9.9	15.6	7.7	3.5	9.7	11.9	10.2	8.3	18.2	7.2	11.1	20.9	5.7	0.9	11.3	12.9	4.2	2.0	19.0	8.6	11.1	7.3	21.0	10.9	14.0	19.1	15.5	14.9	15.1	19.8	16.9	11.0	5.1	6.7	6.9	12.6	7.3	10.4	4.1	13.5	8.1	6.7	10.3	20.7	13.2	14.9	5.7	10.8	9.4	9.2	8.4	14.1	8.9	0.8	7.7	7.4	2.5	6.5	6.8	6.1	5.7	2.2	6.5	4.8	5.0	1.3	8.8	2.3	4.8	9.2	3.4	4.4	6.5	13.9	8.5	7.6	4.0	8.7	4.4	6.6	7.6
FAT1	"CDHF7, CDHR8, FAT"	ENSG00000083857	"FAT atypical cadherin 1"	Q14517	4	186587783-186726722	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 76.4"	"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 63.5;LHCN-M2: 46.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001869, HPA023882"	Enhanced				"Intracellular and membrane"		120000			"HPA001869: AB_1078818, HPA023882: AB_1848429"	"unprognostic (1.98e-1)"	"unprognostic (4.91e-2)"	"unprognostic (2.50e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.53e-2)"	"unprognostic (5.82e-3)"	"unprognostic (2.31e-1)"	"prognostic unfavourable (4.22e-4)"	"unprognostic (6.10e-2)"	"unprognostic (3.05e-2)"	"unprognostic (1.15e-3)"	"unprognostic (6.80e-2)"	"unprognostic (3.57e-2)"	"unprognostic (8.03e-3)"	"unprognostic (9.41e-2)"	"unprognostic (6.25e-3)"	"unprognostic (4.27e-2)"	15.5	1.3	7.9	12.3	9.8	0.4	15.4	11.9	8.4	15.9	40.4	11.8	8.1	17.9	20.6	14.0	9.7	9.6	28.2	21.1	10.0	6.0	29.1	13.3	10.9	1.4	11.4	6.2	9.7	13.8	7.5	10.5	14.6	24.7	15.9	22.9	5.0	13.9	18.2	3.0	13.1	76.4	18.3	12.8	1.7	11.5	7.0	11.2	1.3	10.5	10.2	6.7	17.5	9.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.8	18.6	18.4	0.0	18.5	22.3	4.5	24.8	41.0	12.1	7.7	11.0	11.0	0.0	6.0	63.5	9.0	7.2	30.6	16.5	0.0	2.9	0.0	6.6	11.1	9.2	8.0	6.6	8.0	11.1	22.5	14.7	0.2	0.1	0.0	46.6	5.9	14.3	0.0	4.1	3.1	0.0	5.1	0.3	18.2	17.5	1.9	7.4	4.3	7.3	2.9	0.0	2.9	5.3	34.6	13.4	0.4	15.4	0.1	0.0	0.1	7.9	0.0	11.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.9	9.8	11.9	8.4	10.0	6.0	11.4	6.2	24.7	11.2
FH	fumarase	ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519761	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 93.4"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria			2800000	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favourable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	14.3	28.1	15.7	10.4	20.2	9.3	13.3	15.7	24.4	10.5	22.7	9.9	16.7	23.2	13.7	10.7	17.7	10.3	9.5	59.0	22.9	13.9	35.0	93.4	9.9	13.3	15.2	19.4	9.4	13.9	25.2	11.4	14.3	18.4	12.3	24.4	10.2	18.4	20.6	65.1	13.4	21.4	14.7	14.4	11.1	17.5	14.0	11.7	13.8	12.3	45.2	13.4	13.4	11.2	16.0	26.4	4.5	18.8	10.4	13.9	8.9	29.2	24.5	23.3	21.0	22.9	27.0	36.9	36.3	28.5	41.0	25.8	35.1	18.3	18.6	24.1	27.8	41.7	35.6	27.0	35.8	21.2	11.5	17.4	26.0	29.9	20.5	40.7	15.9	19.5	16.8	23.0	26.0	25.2	53.0	24.1	29.8	14.6	35.1	27.2	24.7	52.7	29.0	25.5	83.5	39.5	24.9	30.0	25.9	30.6	36.3	23.2	27.6	27.7	24.7	18.4	23.8	32.5	60.5	21.6	23.1	22.6	20.6	46.8	26.4	4.5	12.8	2.7	9.7	18.8	12.6	16.0	11.4	9.0	26.4	14.1	13.9	12.7	0.7	10.4	15.7	13.2	13.2	8.9	15.7	20.2	15.7	24.4	22.9	13.9	15.2	19.4	18.4	11.7
FLCN	"BHD, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"				Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favourable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	11.9	15.3	23.6	10.8	41.6	15.6	13.9	49.4	26.9	18.0	21.3	18.5	10.4	25.0	22.1	15.8	11.0	14.5	17.6	17.2	17.2	8.6	9.6	15.5	15.6	11.6	24.2	13.5	25.2	13.7	6.1	20.3	13.3	18.1	15.4	10.7	14.8	10.5	14.8	22.7	12.6	20.2	15.4	14.8	16.5	15.3	12.5	29.1	6.6	15.8	3.9	8.0	15.0	14.8	6.0	2.4	10.5	6.8	4.5	5.0	3.1	6.4	15.7	5.8	7.5	18.9	10.8	8.5	5.8	9.7	9.2	12.8	11.9	5.4	3.2	8.1	7.0	7.5	7.0	3.6	4.8	6.1	5.9	6.5	4.6	6.8	17.5	2.4	18.3	15.8	12.4	14.4	10.7	7.5	8.9	8.3	8.8	8.3	4.3	4.1	5.9	3.9	8.6	26.8	3.7	5.5	7.1	7.0	4.5	6.1	3.7	10.1	5.6	4.5	8.8	21.7	9.4	29.9	7.6	4.1	3.9	3.0	13.7	5.5	8.5	3.6	4.7	2.8	2.9	6.8	4.1	5.3	3.5	2.5	2.4	6.0	3.9	3.4	10.5	4.5	2.2	2.4	5.0	3.1	23.6	41.6	49.4	26.9	17.2	8.6	24.2	13.5	18.1	29.1
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985895	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 262.7"	"Group enriched"	"Detected in some"	8	"HAP1: 53.1;Hep G2: 209.8"	"Cancer enhanced"	"Detected in all"		"liver cancer: 269.0"	"Low region specificity"	"Detected in some"			"Group enriched"	"Detected in some"	4	"naive CD4 T-cell: 5.0;naive CD8 T-cell: 3.5;NK-cell: 1.7"	"Group enriched"	"Detected in many"	12	"NK-cells: 1.7;T-cells: 5.0"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA006316			Supported	"Plasma membrane"	"Intracellular and membrane"			"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavourable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"	30.1	5.9	0.4	3.6	0.7	0.0	50.2	0.6	0.4	3.3	4.5	0.5	2.2	0.5	2.5	11.7	2.0	3.4	9.2	8.0	0.4	1.1	21.2	1.1	37.0	1.9	1.6	0.4	6.0	4.6	0.3	16.9	262.7	1.6	3.6	1.0	6.3	3.8	2.3	4.1	5.5	1.8	3.3	2.1	0.9	4.0	2.1	0.3	2.3	7.2	11.2	3.0	7.6	8.0	0.0	0.2	0.0	0.0	1.7	5.0	0.6	0.0	0.0	2.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.4	0.0	0.0	0.0	0.0	0.0	53.1	0.0	0.0	0.0	2.4	0.0	0.1	209.8	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.1	0.0	0.0	0.0	0.0	14.5	0.6	1.7	4.3	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.8	0.5	0.2	0.0	5.0	3.5	0.0	1.7	0.0	0.0	0.0	0.6	0.4	0.7	0.6	0.4	0.4	1.1	1.6	0.4	1.6	0.3
HNF1A	"HNF1, LFB1, MODY3, TCF1"	ENSG00000135100	"HNF1 homeobox A"		12	120978543-121002512	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"				"Tissue enhanced"	"Detected in some"		"intestine: 24.2;kidney: 17.2;liver: 15.6"	"Group enriched"	"Detected in some"	7	"A549: 6.2;CACO-2: 20.6;Hep G2: 22.4"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"CAB010430, HPA035231"	Enhanced		Supported	Nucleoplasm				Nucleoplasm		"CAB010430: AB_2116746, HPA035231: "	"unprognostic (5.92e-3)"	"unprognostic (8.47e-2)"	"unprognostic (4.12e-3)"	"unprognostic (6.18e-3)"	"unprognostic (3.72e-1)"	"unprognostic (1.27e-2)"	"unprognostic (9.18e-2)"	"unprognostic (9.18e-2)"	"unprognostic (2.99e-1)"	"unprognostic (2.01e-1)"	"unprognostic (9.77e-3)"	"unprognostic (5.21e-2)"	"unprognostic (6.25e-3)"	"unprognostic (5.55e-2)"	"unprognostic (2.48e-1)"		"unprognostic (6.93e-3)"	0.1	0.0	0.1	0.8	0.1	0.0	0.1	0.1	0.1	0.1	17.3	0.1	0.1	13.7	0.1	1.5	0.1	0.8	5.1	0.1	0.1	0.0	17.2	15.6	0.1	0.1	0.1	0.1	0.2	6.3	0.0	0.1	0.1	0.1	0.1	2.1	0.1	0.1	0.1	0.1	0.0	24.2	0.5	0.1	0.1	3.6	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.5	0.5	1.8	0.3	0.3	0.4	0.2	0.0	6.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	20.6	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	22.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	0.3	0.2	0.2	0.3	0.2	0.3	0.4	0.4	0.1	0.5	0.4	0.4	1.6	0.3	0.3	0.5	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.1
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"			"Cancer-related genes, Disease mutation, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol				"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: , HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavourable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"	12.3	11.4	25.2	9.1	34.5	5.0	16.2	16.1	25.3	7.9	9.5	8.1	10.8	8.9	6.2	9.2	22.3	8.3	10.9	28.7	22.2	22.4	8.2	6.5	8.9	8.0	23.2	12.9	7.7	9.7	11.7	10.3	10.1	15.0	10.0	6.2	8.2	10.1	12.7	51.8	32.0	8.2	8.4	17.0	6.5	7.2	6.1	11.0	5.9	8.1	24.5	9.3	9.9	19.8	2.1	1.1	0.7	4.6	0.1	2.0	0.3	21.8	19.4	9.3	8.3	5.8	4.1	12.0	10.9	5.8	17.1	14.6	9.8	8.7	8.4	3.4	14.8	17.4	9.9	26.5	4.8	6.9	22.1	4.3	7.8	8.5	8.8	3.4	3.3	6.2	29.6	9.2	10.0	8.5	8.8	12.3	9.6	17.9	12.7	12.1	9.4	19.3	10.2	11.8	7.5	9.6	5.4	36.3	14.4	10.1	18.1	7.8	14.8	6.7	13.5	15.3	12.1	5.6	14.0	4.6	6.1	6.5	14.4	6.3	14.3	0.0	0.6	0.7	1.4	1.2	1.6	0.8	1.4	1.3	0.7	2.1	2.0	0.6	0.0	0.1	4.6	1.1	2.0	0.3	25.2	34.5	16.1	21.1	22.2	22.4	23.2	12.9	15.0	11.0
KDR	"CD309, FLK1, VEGFR, VEGFR2"	ENSG00000128052	"Kinase insert domain receptor"	P35968	4	55078259-55125595	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"	"Angiogenesis, Differentiation, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	9	"HUVEC TERT2: 31.8;TIME: 35.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			CAB004028	Enhanced		Supported	"Plasma membrane"	"Intracellular and membrane"		7400000	"Plasma membrane"		"CAB004028: AB_2212507"	"unprognostic (1.61e-1)"	"unprognostic (2.03e-1)"	"unprognostic (9.65e-2)"	"unprognostic (1.97e-1)"	"unprognostic (9.63e-2)"	"unprognostic (1.22e-2)"	"unprognostic (1.78e-3)"	"unprognostic (2.59e-2)"	"unprognostic (1.19e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.79e-3)"	"unprognostic (1.34e-1)"	"prognostic unfavourable (7.26e-4)"	"unprognostic (4.00e-2)"	"unprognostic (2.30e-1)"	"unprognostic (3.22e-1)"	"unprognostic (1.86e-1)"	19.7	6.2	1.8	4.4	3.1	0.4	20.5	1.1	2.2	11.4	6.0	1.8	11.5	2.3	28.8	10.2	5.2	9.5	6.2	12.1	2.3	1.7	7.8	10.4	13.2	14.1	3.1	2.9	6.0	8.1	8.0	6.8	34.5	3.9	9.5	1.4	27.6	7.1	10.3	5.3	3.0	3.8	7.7	2.6	4.4	4.2	5.3	1.2	0.5	20.0	5.3	3.0	4.4	12.0	0.1	0.1	0.7	0.0	0.2	0.2	0.1	0.0	0.0	1.7	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.9	0.0	0.0	3.7	0.0	0.0	0.3	0.0	0.0	0.2	31.8	0.0	0.0	0.2	0.0	0.0	0.0	0.8	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	35.9	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.4	0.0	0.1	0.1	0.0	0.7	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.2	0.0	0.1	0.0	0.1	1.8	3.1	1.1	2.2	2.3	1.7	3.1	2.9	3.9	1.2
KIT	"C-Kit, CD117, PBT, SCFR"	ENSG00000157404	"KIT proto-oncogene receptor tyrosine kinase"	P10721	4	54657918-54740715	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"breast: 65.5"	"Group enriched"	"Detected in some"	13	"HEL: 47.7;HMC-1: 100.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7"	"Group enriched"	"Detected in many"	6	"granulocytes: 12.7;NK-cells: 9.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003288, HPA004471, CAB068253, CAB072867, HPA073252"	Enhanced	Supported	Supported	"Plasma membrane"			48000000	"Plasma membrane"		"CAB003288: AB_2335702, CAB068253: , CAB072867: , HPA004471: AB_1078431, HPA073252: "	"unprognostic (1.55e-2)"	"unprognostic (1.91e-1)"	"unprognostic (4.04e-2)"	"unprognostic (8.19e-2)"	"unprognostic (3.96e-2)"	"unprognostic (2.18e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.97e-2)"	"unprognostic (3.60e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.20e-1)"	"unprognostic (1.92e-2)"	"prognostic favourable (5.63e-4)"	"unprognostic (1.34e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.29e-2)"	"unprognostic (2.30e-1)"	8.1	1.6	9.5	6.6	11.8	3.7	65.5	18.3	12.0	12.1	10.3	6.5	10.2	5.8	8.9	4.2	9.9	2.5	15.5	2.4	36.0	4.4	9.4	1.1	13.8	3.8	3.6	6.0	28.5	2.1	1.3	2.3	6.2	5.7	9.6	10.4	20.7	12.9	6.9	1.3	14.6	8.9	10.2	3.9	3.2	12.8	4.0	4.5	0.4	28.9	4.3	4.9	9.8	12.5	0.0	1.8	12.7	0.9	9.7	1.9	0.1	0.0	0.0	0.7	0.0	0.1	0.0	0.0	0.6	0.9	2.5	3.2	0.0	0.0	0.0	0.0	1.4	0.0	0.5	0.0	2.1	0.0	1.1	47.7	0.0	0.0	0.0	0.0	100.2	0.0	0.0	0.0	0.0	5.6	0.6	0.1	0.0	0.0	0.2	0.4	1.3	0.0	0.1	0.0	0.0	0.0	4.7	1.2	0.4	0.0	0.0	0.0	0.0	0.5	0.0	0.1	0.0	1.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	12.7	0.0	10.0	0.1	0.0	1.9	0.0	0.3	0.7	1.8	0.0	0.0	0.0	0.8	9.7	0.9	0.0	0.0	0.1	9.5	11.8	18.3	12.0	36.0	4.4	3.6	6.0	5.7	4.5
LMO1	"RBTN1, RHOM1, TTG1"	ENSG00000166407	"LIM domain only 1"	P25800	11	8224304-8268716	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"		"Group enriched"	"Detected in some"	5	"retina: 29.4;skeletal muscle: 29.1"	"Cell line enhanced"	"Detected in some"		"HeLa: 21.2;SCLC-21H: 8.3;SH-SY5Y: 25.4;SiHa: 5.1"	"Cancer enriched"	"Detected in many"	6	"glioma: 6.4"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (3.74e-3)"	"unprognostic (1.45e-1)"		"unprognostic (4.75e-6)"	"unprognostic (9.34e-2)"	"unprognostic (2.37e-1)"		"unprognostic (1.98e-1)"	"unprognostic (7.06e-3)"	"unprognostic (8.09e-2)"	"unprognostic (2.24e-1)"	"unprognostic (9.05e-2)"	"unprognostic (4.36e-12)"	"unprognostic (1.76e-2)"	"unprognostic (8.88e-2)"	"unprognostic (2.58e-2)"	"unprognostic (3.13e-2)"	0.3	1.7	2.5	0.3	2.1	0.2	0.6	0.4	3.0	0.2	0.2	1.5	0.1	0.4	0.3	2.1	0.6	0.3	0.2	0.5	2.3	5.9	1.0	0.2	0.2	0.2	3.5	0.6	0.2	1.6	0.2	2.1	0.3	2.1	0.3	0.2	29.4	0.2	0.2	29.1	6.4	0.3	0.5	1.2	0.6	0.6	1.6	2.0	0.1	0.2	0.1	0.2	0.5	0.1	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.6	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.3	0.0	0.0	0.0	0.9	0.0	21.2	0.0	0.0	0.0	0.4	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.9	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	8.3	25.4	5.1	2.9	0.1	0.0	0.0	0.0	0.0	0.6	0.0	0.2	0.0	0.0	0.0	1.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.5	2.1	0.4	3.0	2.3	5.9	3.5	0.6	2.1	2.0
LZTR1	"BTBD29, LZTR-1"	ENSG00000099949	"Leucine zipper like transcription regulator 1"	Q8N653	22	20982013-20999038	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067852, HPA068772, HPA071248"	Approved		Approved	Nucleoplasm,Centrosome,Cytosol				Nucleoplasm	"Centrosome, Cytosol"	"HPA067852: , HPA068772: , HPA071248: "	"unprognostic (1.88e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.44e-2)"	"prognostic unfavourable (5.15e-4)"	"unprognostic (9.81e-2)"	"unprognostic (3.55e-1)"	"unprognostic (3.78e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.65e-1)"	"unprognostic (6.25e-2)"	"unprognostic (1.25e-2)"	21.2	16.9	17.3	15.6	17.4	10.3	17.9	20.7	24.7	18.5	18.3	25.3	20.6	18.9	24.9	14.0	16.5	18.3	21.2	15.8	15.4	10.9	17.2	13.1	16.2	12.8	19.6	16.5	21.7	16.2	24.9	26.0	18.8	19.0	16.9	12.9	18.9	17.5	18.0	17.2	15.0	15.7	21.9	14.0	19.3	14.5	10.8	19.2	10.8	19.6	12.6	12.5	18.5	16.4	1.6	2.2	0.2	3.4	1.8	3.0	1.5	6.2	5.1	7.6	9.2	17.6	12.2	6.2	12.8	9.0	7.3	10.0	3.0	2.6	6.6	4.8	14.2	8.4	5.7	10.5	2.9	12.3	13.3	7.1	6.7	4.4	9.4	3.8	9.4	11.2	5.3	9.2	6.7	14.1	29.4	11.5	8.2	3.8	6.8	3.6	2.4	5.6	8.0	11.1	2.6	5.7	8.4	7.5	11.2	6.9	12.1	7.5	5.6	7.1	12.6	17.0	8.7	7.7	6.9	5.0	4.4	2.0	7.7	3.7	8.2	0.0	2.5	0.2	3.0	3.1	1.6	1.6	1.5	2.8	2.2	1.0	2.1	1.5	0.1	1.8	3.4	1.2	0.5	1.5	17.3	17.4	20.7	24.7	15.4	10.9	19.6	16.5	19.0	19.2
MAX	"bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8"	ENSG00000125952	"MYC associated factor X"	P61244	14	65006174-65102695	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HMC-1: 92.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000328, HPA003474"	Supported		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"				Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB000328: AB_2281783, HPA003474: AB_1079317"	"unprognostic (4.50e-3)"	"unprognostic (1.51e-3)"	"unprognostic (4.08e-2)"	"unprognostic (2.87e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.30e-3)"	"unprognostic (1.53e-2)"	"unprognostic (7.36e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.66e-2)"	"prognostic unfavourable (5.57e-4)"	"unprognostic (2.99e-1)"	"unprognostic (4.68e-2)"	"prognostic favourable (2.12e-4)"	"unprognostic (6.03e-2)"	33.4	25.5	31.3	31.5	38.6	68.7	25.8	59.0	38.2	34.6	29.4	37.2	26.3	31.5	34.3	24.0	47.6	38.2	27.9	30.1	29.9	28.4	26.3	21.8	31.4	43.4	37.1	21.6	39.7	20.0	17.4	23.7	30.2	32.7	31.9	25.0	26.8	33.6	37.7	27.8	32.1	40.2	30.7	34.8	42.9	24.8	15.7	40.9	41.3	30.2	22.5	40.7	35.1	40.7	18.7	19.1	87.5	23.6	19.2	30.0	44.8	28.3	11.1	6.8	11.0	18.0	14.1	8.9	10.0	15.3	12.5	15.4	7.1	19.9	23.6	8.4	12.0	14.1	17.1	13.9	9.4	23.8	10.4	36.7	7.3	7.8	21.1	13.8	92.4	16.8	9.9	11.5	12.7	13.8	17.2	9.6	12.6	15.7	31.9	47.6	9.1	18.2	18.1	10.8	10.6	11.5	9.5	14.7	9.6	13.1	14.0	12.8	13.7	17.7	17.2	11.5	13.9	10.6	8.0	11.8	10.0	14.9	14.3	13.3	11.4	87.5	23.6	80.6	21.7	20.1	23.7	18.7	25.4	22.1	19.1	17.6	26.6	22.3	49.5	19.2	17.4	18.3	30.0	44.8	31.3	38.6	59.0	38.2	29.9	28.4	37.1	21.6	32.7	40.9
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavourable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favourable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"	12.1	20.6	13.2	15.6	17.7	11.8	12.5	25.8	26.9	15.5	14.9	16.4	22.2	16.9	14.8	18.4	18.9	17.6	14.7	9.0	12.4	11.5	15.9	23.0	12.8	22.1	12.5	15.6	19.7	25.9	16.8	18.0	16.1	16.0	15.9	11.6	16.6	23.3	19.9	8.4	21.6	15.8	11.0	9.8	20.6	15.3	21.2	12.3	33.2	23.9	6.2	20.3	13.7	15.5	5.2	2.9	3.4	1.5	1.8	4.8	1.0	16.4	22.1	14.1	22.2	15.8	10.3	16.6	11.8	11.8	18.5	12.4	12.7	16.2	23.4	19.4	9.1	23.5	19.1	16.4	11.1	19.9	28.3	19.4	17.7	17.0	14.0	12.4	13.2	11.8	12.3	15.5	12.9	17.1	28.1	8.9	10.2	30.7	31.4	25.2	18.5	33.2	24.4	16.1	22.4	11.9	15.2	20.0	17.6	14.0	19.8	14.4	29.5	13.9	10.8	17.5	16.8	20.9	10.0	14.1	16.3	11.8	13.8	9.7	11.1	0.9	1.3	3.4	3.7	1.5	4.8	3.7	2.6	4.6	1.3	5.2	4.5	2.6	0.2	1.8	0.5	2.9	1.9	1.0	13.2	17.7	25.8	26.9	12.4	11.5	12.5	15.6	16.0	12.3
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993332-37050918	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: , HPA060714: "	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavourable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"	16.3	20.7	18.2	19.4	21.4	24.4	18.7	19.7	19.6	15.3	17.3	28.8	19.6	12.4	18.7	23.6	15.1	16.2	14.4	32.0	17.3	17.7	18.8	20.5	17.8	22.8	19.9	16.0	17.6	18.1	26.0	29.4	17.3	19.2	18.5	17.7	16.7	15.6	18.1	46.4	14.2	14.1	21.1	21.6	20.7	16.5	27.6	21.5	29.0	22.2	19.5	24.5	16.9	21.4	12.0	12.9	13.2	23.2	6.7	13.4	9.0	14.0	22.2	27.8	0.0	12.4	15.5	12.4	21.0	16.8	24.5	26.1	16.7	15.7	34.9	10.4	17.0	9.7	23.8	17.7	26.2	15.8	12.3	24.4	20.5	23.4	13.7	29.9	17.0	11.5	12.6	22.8	28.4	15.1	31.2	16.7	24.8	11.3	31.1	12.3	20.3	12.2	3.1	33.9	14.7	15.5	15.2	5.9	14.0	21.3	22.6	14.0	32.7	21.3	11.9	19.2	20.8	18.9	24.6	13.2	36.1	32.6	14.9	28.3	17.2	10.9	11.7	13.2	13.4	19.5	9.7	12.0	8.4	10.7	12.9	10.3	9.6	9.7	3.4	6.7	23.2	6.1	12.5	9.0	18.2	21.4	19.7	19.6	17.3	17.7	19.9	16.0	19.2	21.5
MPL	"CD110, TPOR"	ENSG00000117400	"MPL proto-oncogene, thrombopoietin receptor"	P40238	1	43337849-43352772	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 8.6"	"Cell line enriched"	"Detected in single"	78	"HEL: 40.7"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"Cell type enriched"	"Detected in single"	5	"neutrophil: 1.6"	"Lineage enriched"	"Detected in single"	5	"granulocytes: 1.6"	"Region enhanced"	"Detected in single"		"cerebral cortex: 1.4"	"Low region specificity"	"Detected in all"			HPA007619			Supported	"Nuclear membrane,Plasma membrane"				"Plasma membrane"	"Nuclear membrane"	"HPA007619: AB_1854080"	"unprognostic (2.74e-1)"	"unprognostic (6.56e-2)"	"unprognostic (2.95e-1)"	"unprognostic (8.71e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.22e-2)"	"unprognostic (5.83e-2)"	"unprognostic (1.03e-1)"	"unprognostic (5.94e-4)"	"unprognostic (1.51e-1)"	"unprognostic (1.19e-4)"	"unprognostic (2.39e-1)"	"unprognostic (3.26e-1)"	"unprognostic (1.03e-4)"	"unprognostic (1.42e-1)"	1.1	0.3	0.9	0.5	0.8	2.0	0.9	0.5	2.2	0.6	0.6	0.5	0.5	0.3	0.9	1.7	0.9	2.1	0.5	3.9	0.8	0.6	0.5	0.5	2.0	0.5	0.9	0.5	6.6	1.1	0.6	0.6	2.2	0.5	1.5	0.7	0.5	0.5	0.7	0.6	0.4	1.2	2.1	2.5	8.6	0.5	2.1	0.5	0.5	2.2	2.4	0.5	0.9	0.5	0.0	0.0	1.6	0.3	0.0	0.0	4.0	0.1	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.5	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.2	0.0	40.7	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.3	0.1	0.0	0.0	0.1	0.4	0.2	0.2	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	0.0	0.0	4.0	0.9	0.8	0.5	2.2	0.8	0.6	0.9	0.5	0.5	0.5
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47402969-47663146	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867"	Approved		Supported	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , HPA066845: "	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavourable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavourable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavourable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"	7.3	9.8	14.2	12.2	25.5	11.4	14.1	22.6	18.1	9.4	11.6	7.6	5.6	6.5	10.5	13.3	10.8	11.1	4.9	8.4	13.0	14.0	7.3	5.5	7.1	19.7	12.5	17.0	7.9	8.4	15.3	9.1	9.9	18.5	7.9	13.8	12.3	9.4	7.3	6.7	10.3	8.0	7.8	13.8	9.4	6.7	13.4	13.5	37.0	13.9	6.6	21.4	8.5	7.6	7.4	2.9	3.9	4.2	12.2	12.6	6.2	28.0	9.6	26.3	14.1	1.9	5.5	15.9	16.7	8.3	20.8	20.1	18.0	12.1	34.5	22.6	5.9	11.9	19.6	9.5	31.4	17.8	14.6	24.9	11.1	16.3	2.0	24.3	8.8	3.1	2.8	17.7	4.8	11.4	41.4	8.0	15.8	11.2	28.1	18.3	49.4	11.4	37.7	46.9	20.2	9.0	14.9	21.8	23.6	14.8	11.5	11.8	11.5	9.5	4.6	13.8	18.1	14.2	18.6	5.1	18.3	48.4	8.4	18.0	8.5	2.8	1.0	3.9	7.9	4.2	8.6	6.3	7.4	9.5	2.3	7.4	12.6	11.9	0.7	12.2	3.2	2.9	10.1	6.2	14.2	25.5	22.6	18.1	13.0	14.0	12.5	17.0	18.5	13.5
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810101	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"				Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavourable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavourable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavourable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"	13.0	20.5	9.7	13.1	18.8	13.6	13.0	20.5	13.1	17.9	13.3	17.6	10.7	6.1	28.2	11.0	12.4	18.3	8.4	8.6	11.4	8.8	9.5	14.6	11.0	21.7	23.9	9.6	43.2	27.6	16.2	17.3	14.9	15.0	14.6	10.3	8.7	12.0	13.2	10.4	10.3	10.5	22.1	14.9	11.6	11.1	25.1	22.0	40.4	13.4	10.4	25.8	14.2	16.4	8.4	8.4	7.6	9.8	9.7	15.1	5.7	27.2	20.3	37.9	9.0	11.4	12.1	17.1	15.2	13.4	15.7	16.6	14.9	9.5	45.0	22.7	16.4	11.5	34.1	19.3	20.5	19.6	17.0	28.8	16.2	15.1	7.0	28.9	10.6	9.8	6.2	16.0	10.7	9.8	25.0	16.6	15.3	19.6	30.7	13.7	33.3	9.4	73.0	49.7	20.3	9.6	17.8	21.2	23.0	21.1	10.1	9.2	12.0	10.2	6.0	18.3	22.4	13.8	19.6	15.6	21.0	75.4	15.5	18.5	11.2	7.6	5.8	4.9	8.4	9.8	10.4	8.4	9.5	8.3	8.4	8.1	15.1	7.6	3.9	9.7	9.3	4.2	9.5	5.7	9.7	18.8	20.5	13.1	11.4	8.8	23.9	9.6	15.0	22.0
MUTYH	MYH	ENSG00000132781	"MutY DNA glycosylase"	Q9UIF7	1	45329163-45340470	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Glycosidase, Hydrolase"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA008732	Uncertain		Supported	Nucleoplasm				Nucleoplasm		"HPA008732: AB_1854219"	"unprognostic (6.30e-3)"	"unprognostic (7.12e-2)"	"unprognostic (6.29e-2)"	"unprognostic (8.80e-2)"	"unprognostic (3.43e-1)"	"unprognostic (5.16e-3)"	"prognostic unfavourable (4.76e-8)"	"unprognostic (2.80e-2)"	"unprognostic (7.12e-3)"	"unprognostic (3.05e-2)"	"unprognostic (7.80e-2)"	"unprognostic (1.14e-1)"	"prognostic unfavourable (7.25e-5)"	"unprognostic (3.50e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.57e-2)"	"unprognostic (5.49e-3)"	7.7	8.4	10.3	12.7	14.8	11.1	8.3	31.6	12.4	10.5	10.1	15.1	11.0	11.1	11.5	9.8	8.3	11.0	10.0	6.1	10.9	7.3	9.7	9.0	7.2	14.0	13.6	10.1	12.9	8.4	7.5	12.5	12.5	11.6	9.1	11.0	12.6	9.5	11.7	8.5	11.1	9.8	7.5	12.6	12.8	11.8	4.9	16.6	14.1	11.9	7.4	12.0	9.3	9.2	7.2	6.5	1.9	8.9	6.6	15.4	6.3	4.9	4.4	10.3	7.0	7.4	5.5	17.9	3.5	4.8	7.5	6.2	9.3	7.1	14.1	6.2	2.4	7.8	5.4	6.4	3.5	11.6	4.1	6.9	7.0	6.6	6.8	5.9	5.0	3.6	6.6	10.1	16.9	5.4	10.7	5.5	3.2	8.1	16.2	5.6	25.9	5.4	22.0	7.9	7.6	3.9	9.5	9.3	7.4	7.6	5.9	11.7	4.7	6.8	3.4	6.6	4.1	5.0	5.5	8.4	9.6	8.6	5.7	9.0	5.0	1.5	5.6	1.9	9.8	8.9	15.4	7.2	10.2	9.9	6.5	7.2	11.3	11.0	0.9	6.6	6.8	5.5	10.3	6.3	10.3	14.8	31.6	12.4	10.9	7.3	13.6	10.1	11.6	16.6
NBN	"AT-V1, AT-V2, ATV, NBS, NBS1"	ENSG00000104320	Nibrin	O60934	8	89933336-90003228	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 76.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001429, CAB003836"	Supported		Approved	"Nucleoplasm,Golgi apparatus"				"Golgi apparatus"	Nucleoplasm	"CAB003836: AB_562172, HPA001429: AB_1854460"	"unprognostic (1.52e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.32e-3)"	"unprognostic (7.46e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.05e-2)"	"prognostic unfavourable (5.46e-5)"	"unprognostic (5.05e-2)"	"unprognostic (4.61e-2)"	"prognostic unfavourable (4.20e-4)"	"unprognostic (1.15e-1)"	"unprognostic (6.68e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.28e-1)"	"unprognostic (2.84e-2)"	"unprognostic (1.03e-1)"	19.2	16.1	17.9	23.6	29.5	41.3	23.0	17.4	21.0	19.3	22.6	12.2	16.9	13.3	33.2	16.6	19.7	17.5	20.2	14.2	19.4	16.7	25.9	19.3	17.9	26.7	16.9	18.1	19.3	17.1	21.0	29.4	13.2	18.4	17.6	20.9	7.1	18.4	17.6	15.7	11.2	18.0	22.2	18.1	26.5	14.7	13.9	18.9	23.4	20.8	14.7	22.8	17.5	16.0	10.1	12.0	21.8	18.5	9.7	8.6	7.6	15.1	8.5	8.6	4.5	4.7	11.8	5.5	10.8	14.4	13.8	15.0	4.9	11.5	22.9	12.6	9.8	5.1	10.4	10.1	17.7	10.7	6.0	19.4	5.3	6.9	9.2	11.6	10.3	8.8	5.4	7.7	17.1	11.1	14.2	13.4	15.6	13.5	17.7	7.3	2.5	9.3	11.9	7.5	13.6	17.8	20.9	2.5	7.9	6.8	76.8	6.4	14.4	8.6	8.3	12.0	8.5	7.2	10.6	6.2	7.1	12.8	12.1	10.9	11.0	14.1	11.1	20.3	8.1	12.5	8.6	10.1	5.9	5.9	12.0	6.1	5.7	6.2	21.8	9.7	18.5	6.6	3.7	7.6	17.9	29.5	17.4	21.0	19.4	16.7	16.9	18.1	18.4	18.9
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	6	"B-cells: 2.3;granulocytes: 6.5;T-cells: 8.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria				Mitochondria		"HPA045502: "	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"	12.9	15.9	22.6	13.3	25.9	5.5	18.5	30.2	26.0	17.6	13.6	19.8	12.2	11.0	16.9	17.0	10.5	15.2	13.1	17.3	21.6	19.6	20.0	15.1	12.7	11.5	19.4	25.6	22.9	16.5	34.1	19.0	19.4	20.9	16.1	14.7	12.1	14.4	20.5	14.8	12.0	12.1	14.5	21.4	11.9	13.0	15.4	21.5	11.6	31.1	7.6	12.4	15.3	19.5	2.3	0.7	6.5	0.4	0.9	8.4	1.0	9.7	12.7	15.5	8.3	13.2	17.2	7.8	8.4	15.3	12.5	14.2	11.4	6.6	9.4	2.4	15.8	17.1	14.0	11.9	21.3	4.5	8.8	8.3	12.0	5.8	9.4	14.8	6.9	13.6	7.6	13.3	16.3	6.0	11.9	9.4	11.9	7.7	12.3	5.4	4.5	4.2	9.7	23.7	7.5	9.5	14.0	6.4	9.6	15.7	5.3	8.7	16.0	9.5	8.8	10.0	14.0	11.8	3.2	8.5	4.1	10.4	8.2	6.3	10.4	6.5	0.4	0.9	2.3	0.2	1.6	2.3	4.4	3.9	0.5	2.1	3.3	3.2	1.0	0.9	0.4	0.7	8.4	1.0	22.6	25.9	30.2	23.5	21.6	19.6	19.4	25.6	20.9	21.5
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"				"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favourable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"	11.8	12.4	23.6	11.1	20.1	10.0	15.4	20.8	28.1	10.8	9.7	9.0	11.8	7.8	10.5	11.3	14.2	11.3	8.0	19.7	26.6	16.4	13.5	11.1	11.9	24.1	18.0	13.5	11.0	12.9	46.8	8.6	6.9	11.4	10.2	8.7	9.5	9.3	15.4	25.7	12.1	8.5	11.9	10.7	10.4	8.8	21.6	10.1	14.9	15.6	11.5	9.9	10.6	10.2	8.5	13.6	6.6	17.3	11.6	15.0	9.8	26.3	10.6	3.7	24.3	7.3	7.3	3.6	21.4	12.1	23.5	20.3	10.5	6.5	7.0	17.8	22.0	9.3	7.7	12.4	21.1	10.2	6.1	8.3	7.9	7.5	7.8	11.9	9.9	6.7	5.7	16.6	20.3	16.5	4.0	6.5	22.8	11.0	7.2	4.7	2.8	10.1	7.5	20.0	6.7	23.8	12.3	5.8	4.0	12.3	8.3	4.8	5.3	4.8	30.6	35.0	39.9	15.2	36.1	10.2	8.1	8.4	9.3	4.7	22.3	6.6	9.5	3.6	15.0	13.5	12.8	8.2	11.3	10.1	13.6	8.5	9.8	9.2	2.3	11.6	17.3	9.3	9.4	9.8	23.6	20.1	20.8	28.1	26.6	16.4	18.0	13.5	11.4	10.1
PALB2	"FANCN, FLJ21816"	ENSG00000083093	"Partner and localizer of BRCA2"	Q86YC2	16	23603160-23641310	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"CAB014895, HPA057000"	Approved		Supported	Nucleoplasm				Nucleoplasm		"CAB014895: , HPA057000: "	"unprognostic (1.11e-1)"	"unprognostic (5.67e-3)"	"prognostic favourable (2.83e-5)"	"unprognostic (1.43e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.61e-2)"	"unprognostic (2.00e-3)"	"unprognostic (5.18e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.00e-2)"	"prognostic unfavourable (2.35e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.04e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.25e-1)"	"unprognostic (7.20e-2)"	"unprognostic (3.21e-1)"	12.4	9.9	10.7	19.6	11.9	6.8	15.2	16.5	14.1	12.4	14.0	10.8	9.1	14.8	10.9	13.5	17.6	9.6	7.8	10.5	10.0	10.6	13.7	16.1	9.2	13.4	9.7	12.5	15.3	10.6	13.7	16.1	9.1	14.9	10.9	12.7	8.6	11.0	14.7	10.3	17.0	14.1	12.8	10.8	14.1	11.0	16.9	10.5	12.9	12.1	12.0	15.3	13.6	13.3	3.7	3.9	7.2	7.7	3.9	5.5	2.0	11.8	9.2	11.1	7.7	9.2	7.3	9.9	8.6	13.1	14.1	17.1	7.8	12.4	12.5	6.3	6.0	10.6	9.8	14.4	16.9	7.3	5.7	7.6	12.6	21.9	8.6	14.0	12.4	8.2	14.7	13.3	15.2	7.5	15.7	6.7	12.4	11.7	14.4	14.6	24.6	5.3	16.7	13.6	17.1	10.7	10.6	8.2	8.1	8.8	10.0	11.2	9.2	9.6	5.4	16.9	6.5	8.3	9.2	7.9	12.8	12.8	11.1	10.3	10.1	7.2	3.3	3.0	4.4	4.2	5.3	3.7	4.9	5.3	3.9	3.1	5.5	4.3	0.2	3.9	7.7	2.8	3.1	2.0	10.7	11.9	16.5	14.1	10.0	10.6	9.7	12.5	14.9	10.5
PDGFRA	"CD140a, GAS9, PDGFR2"	ENSG00000134853	"Platelet derived growth factor receptor alpha"	P16234	4	54229097-54298247	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Chemotaxis, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"ovary: 81.5"	"Cell line enhanced"	"Detected in some"		"ASC diff: 81.0;ASC TERT1: 37.9;BJ hTERT+: 47.0;fHDF/TERT166: 32.7;HHSteC: 27.4;HSkMC: 68.9"	"Cancer enhanced"	"Detected in all"		"glioma: 30.8"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004947, CAB018143"	Supported		Approved	"Nucleoplasm,Plasma membrane,Cell Junctions"	"Intracellular and membrane"		150000	"Nucleoplasm, Plasma membrane, Cell Junctions"		"CAB018143: AB_2162351, HPA004947: "	"unprognostic (1.67e-1)"	"unprognostic (9.35e-2)"	"unprognostic (4.59e-3)"	"unprognostic (1.60e-1)"	"unprognostic (8.92e-2)"	"prognostic favourable (9.33e-4)"	"unprognostic (1.24e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.18e-2)"	"unprognostic (2.18e-1)"	"unprognostic (7.01e-2)"	"prognostic unfavourable (9.79e-6)"	"unprognostic (9.58e-3)"	"unprognostic (9.87e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.72e-3)"	35.0	12.4	12.6	16.1	7.6	0.9	17.2	2.4	20.1	33.2	19.1	9.2	6.4	9.6	27.6	14.6	21.9	22.5	16.2	15.3	8.9	7.4	22.8	8.4	24.1	26.9	9.2	4.0	81.5	6.8	1.6	2.1	25.1	7.2	18.6	15.2	19.2	8.5	8.3	11.9	7.0	17.4	19.7	8.8	51.6	13.6	19.0	9.3	0.5	11.3	12.8	4.3	35.9	24.6	0.9	0.4	2.5	0.4	0.3	0.8	0.3	0.0	0.0	0.2	0.1	81.0	37.9	0.1	4.2	47.0	0.0	0.1	11.2	0.0	0.1	0.1	32.7	0.1	3.2	0.0	0.0	0.4	0.1	0.1	0.1	0.2	27.4	0.0	0.0	68.9	0.0	5.3	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.2	0.6	0.1	0.1	0.0	0.0	0.0	0.3	0.1	6.6	0.0	0.1	0.0	0.1	0.0	0.1	14.8	0.5	16.2	0.0	0.0	0.0	0.1	0.4	0.0	0.3	2.5	0.4	0.2	0.5	0.2	0.2	0.6	0.8	0.4	0.0	0.9	0.7	0.4	2.3	0.3	0.3	0.4	0.2	0.3	12.6	7.6	2.4	7.3	8.9	7.4	9.2	4.0	7.2	9.3
PHOX2B	"NBPhox, Phox2b, PMX2B"	ENSG00000109132	"Paired like homeobox 2b"	Q99453	4	41744082-41748970	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"adrenal gland: 14.5;brain: 24.8"	"Cell line enriched"	"Detected in single"	91	"SH-SY5Y: 52.3"	"Not detected"	"Not detected"			"Region enriched"	"Detected in single"	99	"pons and medulla: 24.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enriched"	"Detected in single"	17	"pons and medulla: 5.9"	"Region enriched"	"Detected in single"	38	"pons and medulla: 2.0"	"HPA074325, HPA074941"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"HPA074325: , HPA074941: "			"unprognostic (1.01e-1)"								"unprognostic (2.47e-1)"			"unprognostic (5.27e-2)"				0.0	14.5	0.0	2.1	0.0	0.0	0.0	0.0	0.0	0.0	5.6	0.2	0.0	0.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	1.4	0.0	0.0	0.0	24.8	0.2	1.4	0.8	0.0	0.0	0.0	0.0	3.2	0.5	0.4	0.0	0.9	0.1	0.0	0.1	0.0	0.0	0.0	0.6	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	52.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	24.8	0.0
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5973239-6009125	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA066490, HPA070310"	Approved		Enhanced	Nucleoplasm				Nucleoplasm		"CAB010235: AB_2167281, HPA066490: , HPA070310: "	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favourable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"	6.3	7.4	8.7	6.0	19.8	3.6	8.1	15.5	21.2	6.2	6.0	11.5	6.9	6.4	6.4	6.3	7.5	7.5	5.0	5.3	9.0	10.3	14.2	5.8	5.5	9.1	8.4	9.5	7.5	7.1	16.6	7.1	5.9	16.2	7.0	6.2	8.0	7.1	7.8	5.7	14.8	6.8	7.1	7.5	6.9	6.1	4.8	5.8	7.5	12.4	5.7	10.7	7.7	6.5	6.2	5.8	7.2	7.9	4.0	9.3	6.3	9.5	10.5	8.4	20.9	6.6	9.8	7.2	5.2	3.9	5.0	4.1	9.1	6.9	18.1	6.2	7.4	13.2	12.6	3.3	5.5	7.1	5.1	7.9	8.5	6.5	11.3	9.7	5.4	10.3	9.6	4.0	15.0	9.2	14.7	8.8	8.3	8.8	2.9	6.9	8.5	6.4	9.9	10.1	9.2	10.6	7.2	7.7	16.6	10.1	14.7	11.0	18.2	6.8	7.8	6.4	14.3	9.4	9.3	11.8	19.7	18.2	4.5	9.5	14.6	7.2	5.4	3.1	8.4	7.9	9.3	6.2	6.6	7.2	5.8	5.6	8.8	6.2	2.4	4.0	3.2	5.3	6.4	6.3	8.7	19.8	15.5	21.2	9.0	10.3	8.4	9.5	16.2	5.8
POLD1	"CDC2, POLD"	ENSG00000062822	"DNA polymerase delta 1, catalytic subunit"	P28340	19	50384204-50418016	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA excision, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004375, HPA046524"	Supported		Supported	Nucleoplasm				Nucleoplasm		"CAB004375: AB_675487, HPA046524: "	"unprognostic (2.45e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.59e-1)"	"unprognostic (4.35e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.85e-2)"	"prognostic unfavourable (2.87e-6)"	"unprognostic (4.12e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.83e-1)"	"unprognostic (5.08e-1)"	"unprognostic (3.92e-3)"	"unprognostic (4.01e-3)"	"unprognostic (1.28e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.89e-1)"	"unprognostic (3.70e-2)"	7.9	5.7	5.4	18.3	9.9	31.6	6.6	9.4	5.4	8.2	10.0	6.1	5.9	6.8	9.5	7.2	11.3	6.9	5.2	5.5	4.4	3.2	7.6	9.3	10.9	15.7	7.0	3.6	8.2	8.4	5.2	5.1	10.9	6.7	6.3	5.2	4.9	8.1	5.4	7.2	13.1	9.9	6.2	7.7	14.1	6.5	13.2	6.5	27.4	12.1	8.1	14.2	5.9	7.8	9.3	10.5	2.1	8.5	5.4	7.3	5.6	18.1	25.0	13.7	7.9	1.7	1.5	14.1	11.3	5.0	13.9	17.8	13.6	14.4	26.0	6.4	3.4	14.9	16.2	12.3	4.8	21.9	43.5	22.6	24.2	17.9	1.6	21.5	20.0	2.9	3.8	12.6	3.8	7.1	24.3	20.2	5.8	12.2	33.3	33.7	16.1	18.2	33.1	23.0	22.8	4.4	17.3	14.3	12.9	11.2	13.8	2.6	7.6	20.4	5.6	7.1	23.0	7.6	19.8	19.1	31.4	27.8	7.7	24.3	6.9	1.6	6.2	2.1	7.3	7.8	6.2	7.8	6.5	5.9	5.7	9.3	6.5	5.9	1.1	5.4	8.5	10.5	4.5	5.6	5.4	9.9	9.4	5.4	4.4	3.2	7.0	3.6	6.7	6.5
POLE	POLE1	ENSG00000177084	"DNA polymerase epsilon, catalytic subunit"	Q07864	12	132623753-132687365	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Region enhanced"	"Detected in all"		"cerebellum: 34.8"	"Cell type enhanced"	"Detected in some"		"NK-cell: 4.8"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"HPA058210, HPA067385"			Supported	"Nucleoplasm,Plasma membrane"				Nucleoplasm	"Plasma membrane"	"HPA058210: , HPA067385: "	"unprognostic (1.60e-1)"	"unprognostic (1.77e-3)"	"unprognostic (2.00e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.01e-2)"	"unprognostic (3.96e-3)"	"unprognostic (2.23e-1)"	"prognostic unfavourable (1.44e-4)"	"unprognostic (7.12e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.67e-1)"	"prognostic unfavourable (3.19e-8)"	"unprognostic (8.60e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.28e-1)"	"unprognostic (9.95e-2)"	6.1	3.4	6.7	10.2	4.4	29.3	6.2	34.8	14.4	7.0	6.6	2.0	7.6	7.3	6.1	4.4	7.5	6.2	6.5	4.7	5.6	1.6	3.8	8.6	5.4	8.2	3.3	4.3	8.7	6.8	3.6	3.1	6.5	5.1	6.8	7.7	4.3	8.7	7.4	8.9	17.9	8.5	6.8	3.7	16.7	7.8	25.6	4.4	29.8	5.1	6.0	10.3	6.7	8.7	0.5	1.7	0.8	0.8	4.8	0.7	0.5	11.1	14.9	22.1	10.6	4.7	3.6	19.7	11.4	5.2	13.7	10.0	18.0	6.6	12.8	4.8	6.2	15.5	15.4	7.7	8.4	5.9	19.5	20.2	19.2	8.8	0.9	15.8	11.6	2.8	3.0	14.2	4.7	4.8	22.6	7.2	6.7	18.1	25.9	28.9	17.2	8.9	21.5	12.5	5.8	4.3	18.3	18.5	10.6	13.3	10.9	2.5	16.1	9.8	4.3	12.5	12.8	9.4	11.5	9.6	6.5	20.1	6.8	21.9	8.8	0.0	0.3	0.8	0.5	0.1	0.7	0.5	0.3	0.4	0.7	0.3	0.5	0.3	0.1	4.8	0.8	1.7	0.6	0.5	6.7	4.4	34.8	14.4	5.6	1.6	3.3	4.3	5.1	4.4
POLQ	POLH	ENSG00000051341	"DNA polymerase theta"	O75417	3	121431427-121546641	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 9.5;lymphoid tissue: 21.4"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"basophil: 1.6"	"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in many"		"cerebellum: 5.2"	"HPA048931, HPA053359"			Uncertain	"Nucleoplasm,Golgi apparatus,Cytosol"				"Nucleoplasm, Golgi apparatus, Cytosol"		"HPA048931: , HPA053359: "	"unprognostic (1.59e-1)"	"unprognostic (4.18e-2)"	"unprognostic (2.66e-2)"	"prognostic unfavourable (5.46e-5)"	"unprognostic (2.70e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.09e-5)"	"unprognostic (8.55e-3)"	"unprognostic (1.09e-4)"	"unprognostic (2.86e-1)"	"unprognostic (5.59e-5)"	"unprognostic (2.06e-3)"	"unprognostic (0.00e+0)"	"prognostic favourable (1.04e-4)"	"unprognostic (1.76e-1)"	"unprognostic (6.01e-2)"	"unprognostic (5.76e-2)"	0.5	0.8	0.2	8.2	0.7	9.5	0.6	0.6	0.4	0.9	3.5	0.2	0.8	2.0	0.9	0.6	6.0	0.3	0.4	0.8	0.3	0.2	0.4	0.6	0.9	4.7	0.3	0.0	0.4	0.4	0.0	0.2	2.8	0.3	0.4	3.7	0.1	1.1	0.8	1.2	2.4	3.9	0.5	0.4	2.6	1.1	5.8	0.6	21.4	0.3	5.6	7.5	0.6	1.7	0.5	1.1	1.6	0.4	0.0	0.4	0.0	13.3	9.1	7.8	5.5	0.7	0.9	7.1	6.3	2.4	7.5	10.1	7.2	5.0	15.9	2.9	3.4	10.6	9.2	4.1	12.8	4.6	5.0	10.2	5.6	4.5	0.0	11.0	9.3	0.1	0.3	6.8	4.2	3.7	6.7	12.1	7.8	5.2	9.9	6.4	7.4	4.4	8.4	9.4	5.6	2.4	7.7	4.3	3.8	7.3	4.0	2.6	3.7	10.9	2.8	6.6	8.7	2.6	8.2	6.1	4.9	16.5	3.2	8.2	4.9	1.6	0.2	0.0	0.3	0.2	0.0	0.3	0.4	0.3	0.4	0.5	0.0	0.2	0.0	0.0	0.4	1.1	0.1	0.0	0.2	0.7	0.6	0.4	0.3	0.2	0.3	0.0	0.3	0.6
PRF1	"HPLH2, P1, PFP"	ENSG00000180644	"Perforin 1"	P14222	10	70597348-70602775	"Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters"	Cytolysis		"Cancer-related genes, Disease mutation, Familial hemophagocytic lymphohistiocytosis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 100.3;lymphoid tissue: 38.7"	"Cell line enriched"	"Detected in some"	11	"HDLM-2: 71.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in some"			"Group enriched"	"Detected in many"	4	"gdT-cell: 100.3;MAIT T-cell: 70.9;memory CD8 T-cell: 54.9;naive CD8 T-cell: 36.1;NK-cell: 65.1"	"Group enriched"	"Detected in many"	48	"NK-cells: 65.1;T-cells: 100.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB002436, HPA037940"	Approved		Approved	Cytosol	"Intracellular and membrane"		960000	Cytosol		"CAB002436: AB_563955, HPA037940: "	"unprognostic (6.11e-3)"	"unprognostic (1.26e-2)"	"unprognostic (1.71e-1)"	"prognostic favourable (2.09e-4)"	"unprognostic (1.87e-2)"	"prognostic favourable (3.54e-4)"	"unprognostic (6.98e-3)"	"unprognostic (2.62e-1)"	"unprognostic (1.44e-3)"	"unprognostic (1.69e-2)"	"unprognostic (5.22e-2)"	"unprognostic (1.45e-1)"	"prognostic unfavourable (1.08e-5)"	"unprognostic (7.38e-2)"	"unprognostic (2.70e-1)"	"unprognostic (7.97e-3)"	"unprognostic (5.22e-3)"	8.8	1.3	0.9	5.5	1.1	15.3	2.4	0.5	0.7	1.7	3.8	0.4	0.2	1.4	4.4	2.9	2.7	1.7	5.3	4.1	0.8	0.9	1.8	6.5	19.6	11.3	2.5	0.3	2.1	1.6	0.0	1.1	3.1	1.2	3.3	0.8	3.9	2.5	3.3	2.6	0.9	5.1	1.2	1.4	38.7	3.1	1.6	0.2	12.7	2.8	1.0	10.3	3.2	1.7	0.4	0.3	1.7	0.2	65.1	100.3	46.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	71.0	0.0	0.4	0.0	2.1	0.0	0.0	3.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.4	0.2	0.0	100.3	0.1	70.9	0.4	14.6	54.9	0.2	0.2	6.2	36.1	1.7	65.1	0.2	0.3	11.1	46.7	0.9	1.1	0.5	0.7	0.8	0.9	2.5	0.3	1.2	0.2
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol			11000000	Cytosol		"CAB019378: , HPA049979: "	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"	47.1	48.0	41.7	34.5	54.8	14.6	38.7	40.4	57.4	48.2	23.8	44.9	31.4	15.1	43.6	37.7	29.6	43.2	37.4	122.7	42.5	52.3	49.2	43.4	47.3	29.5	50.1	43.6	62.5	19.1	107.8	41.9	47.3	57.7	35.6	24.2	32.2	47.5	43.6	99.8	22.8	19.3	39.4	52.8	35.3	25.1	36.9	40.1	28.2	51.8	23.6	29.2	33.8	33.4	11.3	26.9	52.6	28.7	18.5	13.0	22.9	16.4	31.6	40.6	24.3	54.2	61.6	6.1	22.2	45.8	34.7	30.7	12.3	22.2	16.7	15.3	48.4	13.6	30.0	36.0	49.9	11.3	10.7	25.8	27.5	40.2	39.3	19.7	29.0	44.0	37.4	40.0	33.8	57.6	11.6	26.3	42.0	31.1	21.7	10.6	15.0	21.6	15.2	67.3	18.4	52.6	35.8	14.8	20.0	20.3	37.2	85.5	29.0	27.9	40.8	49.0	23.4	22.1	20.6	21.9	15.5	24.9	29.6	18.8	30.5	31.1	26.1	46.3	13.0	25.5	13.0	11.3	9.8	11.6	26.9	8.5	8.9	9.8	52.6	18.5	28.7	8.8	12.3	22.9	41.7	54.8	40.4	57.4	42.5	52.3	50.1	43.6	57.7	40.1
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease mutation, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 15.5;WM-115: 37.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"gdT-cell: 8.9"	"Lineage enriched"	"Detected in many"	8	"T-cells: 8.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"				"Golgi apparatus"		"CAB013717: , HPA075072: "	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"	4.1	3.8	6.7	6.0	9.5	0.7	7.9	21.0	6.4	28.5	12.5	6.1	8.0	7.8	16.2	4.2	3.0	7.4	13.2	2.8	7.0	6.6	4.9	2.2	7.1	4.5	9.5	3.2	5.2	10.8	3.4	4.0	3.7	6.9	6.9	12.3	11.2	6.9	9.5	2.7	4.3	10.9	8.5	5.1	3.8	12.1	14.3	7.9	1.0	6.3	1.9	3.2	11.3	6.9	1.0	0.0	0.0	0.0	0.3	8.9	1.8	5.0	2.4	10.7	6.7	1.6	2.7	6.1	1.0	0.9	1.2	0.7	2.5	2.5	4.1	1.7	1.9	11.6	6.1	0.8	0.7	4.0	4.0	0.0	2.5	1.1	1.4	0.1	2.2	2.5	1.2	1.1	0.7	2.2	3.6	4.7	0.5	1.0	0.0	1.5	15.5	0.9	0.0	8.2	2.1	0.8	0.7	7.3	3.7	3.6	3.6	1.6	0.9	1.0	0.5	1.4	7.0	7.1	0.7	9.5	8.2	2.7	2.0	2.0	37.0	0.0	0.0	0.0	8.9	0.0	5.3	1.0	1.7	3.8	0.0	0.3	2.8	3.2	0.0	0.3	0.0	0.0	1.4	1.8	6.7	9.5	21.0	6.4	7.0	6.6	9.5	3.2	6.9	7.9
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863113-87971930	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"neutrophil: 29.6"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB004076, HPA031335"	Approved		Supported	Nucleoplasm,Cytosol	"Secreted - unknown location"			Nucleoplasm	Cytosol	"CAB004076: AB_390810, HPA031335: "	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavourable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"	42.4	24.1	17.7	20.9	17.7	13.5	32.8	39.9	19.7	43.1	26.7	9.9	19.0	15.1	29.8	22.8	26.8	30.3	21.0	19.1	16.0	17.4	19.6	32.4	27.2	30.4	15.7	19.5	29.1	21.3	16.4	23.6	36.4	14.2	35.3	17.7	21.6	16.8	20.8	16.8	20.4	25.4	26.0	11.7	40.9	17.8	18.7	12.5	49.7	25.2	13.3	18.6	29.6	30.9	4.3	5.1	29.6	11.0	4.3	4.7	2.0	10.4	4.9	5.7	5.1	13.1	9.0	5.1	5.6	12.5	6.6	9.3	5.0	12.9	12.3	3.8	9.2	6.3	7.5	6.4	10.5	6.2	2.1	4.1	12.8	6.1	14.0	13.8	7.1	6.1	17.9	8.3	10.8	9.3	3.1	33.6	6.0	8.0	7.7	25.1	2.1	0.0	12.0	3.0	9.1	10.3	6.0	2.0	9.2	7.5	3.5	9.4	9.9	20.0	8.1	21.9	5.1	8.5	4.5	11.1	14.3	14.1	6.8	13.1	1.3	8.3	7.9	12.2	3.6	11.0	3.9	4.3	4.0	3.5	5.1	3.7	4.7	4.5	29.6	4.3	7.2	4.2	3.5	2.0	17.7	17.7	39.9	19.7	16.0	17.4	15.7	19.5	14.2	12.5
PTPN13	"PTP-BAS, PTP-BL, PTP1E, PTPL1"	ENSG00000163629	"Protein tyrosine phosphatase, non-receptor type 13"	Q12923	4	86594315-86815171	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 44.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9"	"Group enriched"	"Detected in many"	7	"monocytes: 4.9;T-cells: 2.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002213, HPA063119"	Approved		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"				Nucleoplasm	"Nucleoli fibrillar center, Cytosol"	"CAB002213: AB_564089, HPA063119: "	"unprognostic (5.36e-2)"	"unprognostic (4.46e-1)"	"unprognostic (1.11e-1)"	"unprognostic (2.54e-3)"	"unprognostic (4.02e-1)"	"unprognostic (9.03e-3)"	"unprognostic (4.43e-2)"	"unprognostic (4.38e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.05e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.28e-3)"	"unprognostic (3.95e-3)"	"unprognostic (2.26e-1)"	"unprognostic (2.66e-1)"	"unprognostic (2.85e-2)"	10.3	5.9	10.8	2.7	16.9	0.7	9.9	5.7	11.6	15.9	4.1	13.0	7.6	1.2	10.8	21.2	18.7	11.4	6.5	5.3	10.4	5.7	22.1	1.6	18.0	4.3	16.9	7.9	24.1	4.3	26.6	38.3	3.0	14.2	12.0	2.4	39.0	5.9	9.4	1.0	43.0	2.3	8.7	10.3	3.5	3.6	12.2	17.6	1.9	16.9	12.4	11.8	15.7	17.6	0.0	0.5	0.1	4.9	0.1	2.3	0.1	5.0	2.5	44.4	4.3	18.8	16.4	0.0	9.3	19.1	3.5	4.5	0.0	2.5	0.0	2.0	10.3	16.7	7.7	14.1	6.9	0.1	5.7	4.2	5.5	0.0	2.3	7.4	0.0	10.5	4.5	2.6	8.6	0.0	0.0	7.2	0.0	2.2	0.6	2.7	10.1	1.9	1.5	0.0	0.0	13.5	21.2	2.6	3.7	2.8	6.2	5.1	3.6	0.2	0.0	3.4	2.7	0.0	1.2	7.6	0.0	0.0	3.6	0.0	1.5	0.0	0.2	0.0	0.2	3.0	2.3	0.0	2.2	0.3	0.5	0.0	0.0	0.0	0.1	0.1	4.9	0.0	0.1	0.1	10.8	16.9	5.7	11.6	10.4	5.7	16.9	7.9	14.2	17.6
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303726-48599436	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MOLT-4: 57.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: "	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavourable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"	19.6	21.5	14.9	23.2	18.4	14.7	28.1	25.6	19.4	18.0	13.2	11.5	19.0	12.3	16.8	19.5	27.9	12.7	15.3	19.5	15.4	15.3	18.1	12.1	25.4	30.1	17.0	11.8	15.2	11.6	12.8	17.2	21.5	16.0	15.5	15.3	11.6	20.0	17.4	27.9	20.3	14.3	16.8	23.6	29.4	13.7	14.4	15.3	39.1	19.9	15.8	25.3	17.4	23.6	20.5	10.3	13.2	12.2	3.6	4.6	4.0	9.0	4.9	13.4	14.4	6.6	7.7	6.1	17.9	14.9	18.9	16.1	4.2	16.1	11.7	4.1	11.9	12.6	17.4	14.4	28.9	16.4	6.6	21.6	10.1	7.1	7.1	18.5	20.5	4.3	8.9	12.2	15.7	13.0	7.1	9.7	21.6	4.3	57.9	9.3	6.5	5.4	24.9	13.4	13.5	19.6	8.8	0.6	13.7	17.7	8.9	14.6	9.7	24.2	10.1	11.7	7.7	14.3	16.1	4.3	1.2	0.1	6.2	11.6	15.8	11.0	9.7	5.0	4.6	12.2	3.7	17.4	3.8	4.6	9.3	20.5	3.2	3.8	13.2	3.6	12.1	10.3	4.5	4.0	14.9	18.4	25.6	19.4	15.4	15.3	17.0	11.8	16.0	15.3
RECQL4	RecQ4	ENSG00000160957	"RecQ like helicase 4"		8	144511288-144517845	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"				"Tissue enhanced"	"Detected in many"		"bone marrow: 21.0;lymphoid tissue: 18.9"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in some"			"Group enriched"	"Detected in many"	14	"B-cells: 1.9;monocytes: 1.0;T-cells: 1.6"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"CAB017800, HPA025821"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB017800: , HPA025821: AB_1856168"	"unprognostic (5.92e-2)"	"unprognostic (1.86e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.17e-2)"	"unprognostic (3.17e-2)"	"prognostic unfavourable (1.91e-4)"	"unprognostic (1.12e-2)"	"unprognostic (4.12e-2)"	"unprognostic (7.53e-2)"	"unprognostic (2.65e-2)"	"unprognostic (4.26e-2)"	"unprognostic (1.12e-3)"	"unprognostic (8.82e-3)"	"unprognostic (1.74e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.34e-1)"	2.0	1.6	2.6	12.3	5.6	21.0	2.8	11.5	3.7	1.8	4.3	1.5	1.6	5.6	2.5	4.9	9.4	1.5	1.9	1.9	2.3	1.7	1.6	1.9	1.6	5.9	1.5	2.2	1.9	3.5	0.3	2.4	2.7	2.2	7.7	1.5	1.4	5.4	0.9	2.1	9.4	4.8	1.1	1.7	4.7	3.0	18.1	1.8	18.9	2.5	5.3	8.0	1.6	1.8	1.9	0.1	0.0	1.0	0.0	1.6	0.2	10.3	18.5	8.7	18.2	0.5	0.8	15.2	10.5	1.9	7.8	6.6	18.2	15.3	7.1	7.0	1.7	12.6	5.7	4.5	2.1	12.4	21.8	25.5	31.7	13.5	0.1	6.4	21.2	1.1	0.6	8.7	1.7	2.1	25.3	9.2	2.6	32.0	23.5	17.5	6.0	22.2	24.6	6.8	11.8	2.1	11.2	17.1	10.3	14.2	11.9	3.7	14.5	14.2	2.9	12.6	38.3	15.1	19.3	5.1	5.4	11.9	7.3	20.0	12.6	0.0	0.1	0.0	1.1	1.0	0.0	1.9	0.5	1.1	0.1	0.0	0.9	1.6	0.0	0.0	0.0	0.1	0.0	0.2	2.6	5.6	11.5	3.7	2.3	1.7	1.5	2.2	2.2	1.8
RET	"CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51"	ENSG00000165731	"Ret proto-oncogene"	P07949	10	43077027-43130351	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 63.9"	"Cell line enhanced"	"Detected in some"		"MCF7: 17.6;NB-4: 11.6;SH-SY5Y: 89.7;THP-1: 26.8"	"Cancer enhanced"	"Detected in many"		"breast cancer: 11.0"	"Low region specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"non-classical monocyte: 6.7"	"Group enriched"	"Detected in many"	13	"dendritic cells: 2.1;monocytes: 6.7"	"Low region specificity"	"Detected in many"			"Region enriched"	"Detected in many"	6	"midbrain: 95.5"	"CAB002581, HPA008356, HPA008495"	Approved	Supported	Approved	"Golgi apparatus,Plasma membrane,Cytosol"			260000	"Golgi apparatus, Cytosol"	"Plasma membrane"	"CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: "	"unprognostic (7.94e-2)"	"unprognostic (3.68e-2)"	"unprognostic (4.49e-1)"	"prognostic unfavourable (5.02e-4)"	"unprognostic (1.15e-1)"	"unprognostic (9.13e-4)"	"unprognostic (1.27e-2)"	"unprognostic (3.62e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.54e-3)"	"unprognostic (4.43e-1)"	"unprognostic (9.35e-5)"	"unprognostic (1.64e-3)"	"unprognostic (8.28e-2)"	"unprognostic (3.67e-3)"	"unprognostic (2.02e-2)"	1.8	15.2	1.1	1.8	1.3	0.7	1.2	4.1	9.0	1.9	3.1	0.9	1.1	1.5	0.9	0.6	1.2	0.7	1.0	1.2	1.5	5.8	1.0	11.7	0.7	0.8	17.5	1.2	0.8	1.3	63.9	6.3	0.8	16.8	2.2	1.5	2.8	13.6	2.0	4.5	1.1	2.6	1.1	2.8	0.6	2.1	2.0	0.0	0.1	0.8	5.1	0.6	1.9	1.4	0.2	2.1	0.0	6.7	0.0	0.3	0.4	0.0	0.1	0.0	0.5	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	17.6	0.0	11.6	2.1	0.0	0.0	0.0	0.0	0.0	0.0	1.3	89.7	0.0	0.0	0.0	1.2	26.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.8	0.0	0.2	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	6.7	2.1	0.3	0.4	1.1	1.3	4.1	9.0	1.5	5.8	17.5	1.2	16.8	0.0
SBDS	"CGI-97, FLJ10917, SDS, SWDS"	ENSG00000126524	"SBDS, ribosome maturation factor"	Q9Y3A5	7	66987677-66995601	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ribosome biogenesis"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028891	Approved		Supported	Nucleoplasm,Cytosol			55000	"Nucleoplasm, Cytosol"		"HPA028891: AB_10601500"	"prognostic unfavourable (1.49e-4)"	"unprognostic (1.87e-2)"	"unprognostic (5.73e-2)"	"unprognostic (1.71e-3)"	"unprognostic (8.06e-3)"	"prognostic unfavourable (3.65e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.44e-1)"	"unprognostic (6.99e-2)"	"unprognostic (7.84e-3)"	"unprognostic (4.59e-1)"	"unprognostic (1.04e-2)"	"unprognostic (9.38e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.30e-1)"	"unprognostic (5.06e-3)"	40.9	34.5	37.7	18.7	44.0	41.7	44.5	23.6	43.2	30.7	37.5	35.3	20.2	39.1	35.6	27.3	40.8	27.7	34.0	70.0	39.2	40.9	36.9	38.4	32.1	16.7	50.6	36.6	31.9	27.5	50.4	26.9	38.6	44.6	35.1	35.7	20.1	23.5	40.5	130.7	26.1	34.4	52.0	63.2	16.7	32.8	15.9	48.2	7.2	33.9	38.7	15.6	54.0	38.0	21.6	15.5	20.8	12.6	16.6	39.1	19.4	31.0	13.2	11.7	10.6	42.7	31.9	13.1	52.9	43.6	40.5	31.2	27.1	16.0	11.5	40.2	48.3	15.1	19.7	31.4	43.6	11.0	26.0	5.7	24.6	16.2	38.0	14.4	7.9	28.8	42.3	30.8	53.6	24.9	41.7	12.6	62.9	18.6	7.6	21.0	13.0	31.4	5.8	25.2	24.2	42.7	13.9	18.0	12.4	26.5	45.9	35.1	34.2	12.2	33.1	54.8	18.7	27.7	38.5	7.8	9.2	26.4	18.8	23.7	30.3	20.8	11.1	20.2	23.4	12.6	29.6	21.6	30.6	27.2	11.3	18.7	39.1	31.5	4.7	16.6	11.2	15.5	25.9	19.4	37.7	44.0	23.6	43.2	39.2	40.9	50.6	36.6	44.6	48.2
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-256700	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease mutation, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 100.1;skeletal muscle: 114.0"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria			780000	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavourable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favourable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"	17.6	31.4	15.3	11.5	20.3	10.6	12.8	18.8	29.0	10.2	29.4	17.3	10.0	44.3	11.3	12.1	15.3	12.6	14.8	100.1	15.8	14.5	36.5	55.4	10.7	11.7	19.6	19.3	14.5	14.7	23.2	9.5	9.2	29.7	10.7	24.6	14.5	17.3	12.0	114.0	11.5	39.9	16.5	13.2	13.9	21.2	14.6	14.8	15.7	12.5	39.6	12.5	13.2	11.1	28.3	31.9	29.1	29.2	27.1	48.9	32.4	18.4	29.9	12.3	20.1	21.2	15.9	33.4	14.2	18.1	24.5	25.0	32.4	25.1	22.8	45.0	16.2	23.9	21.7	29.0	14.5	48.6	19.9	11.6	82.6	42.0	13.1	14.4	15.1	15.8	18.7	18.3	9.7	26.5	18.6	19.0	11.5	28.2	19.1	39.0	4.2	37.9	24.7	17.9	44.2	52.2	24.5	13.6	7.8	67.0	43.3	17.6	26.3	18.3	19.2	18.2	17.9	10.8	11.7	20.2	8.6	16.8	17.6	20.9	11.5	17.8	24.4	29.1	36.4	29.2	32.1	28.3	34.8	35.1	31.9	24.5	34.5	31.7	5.9	27.1	24.1	20.5	48.9	32.4	15.3	20.3	18.8	29.0	15.8	14.5	19.6	19.3	29.7	14.8
SDHAF2	"C11orf79, FLJ20487, PGL2, SDH5"	ENSG00000167985	"Succinate dehydrogenase complex assembly factor 2"	Q9NX18	11	61430042-61447529	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		Chaperone	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039464, HPA039732"	Supported		Approved	Nucleoli,Mitochondria,Cytosol				"Mitochondria, Cytosol"	Nucleoli	"HPA039464: AB_10962146, HPA039732: AB_10962868"	"unprognostic (5.31e-2)"	"unprognostic (1.12e-2)"	"unprognostic (3.13e-1)"	"unprognostic (1.30e-2)"	"unprognostic (1.40e-1)"	"unprognostic (6.71e-2)"	"unprognostic (1.98e-3)"	"unprognostic (9.06e-2)"	"unprognostic (2.17e-1)"	"unprognostic (2.09e-3)"	"unprognostic (4.21e-3)"	"unprognostic (1.50e-1)"	"unprognostic (1.81e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.78e-1)"	"unprognostic (1.45e-1)"	"unprognostic (4.48e-2)"	23.7	33.0	22.2	22.4	27.2	34.1	24.8	19.9	33.8	20.5	22.1	23.4	21.0	22.3	23.3	33.5	25.3	25.8	21.1	32.5	20.8	26.9	26.8	39.1	19.9	36.7	24.3	25.0	25.7	22.7	23.3	38.4	26.7	25.2	26.1	24.9	32.0	28.1	21.5	31.4	22.9	27.9	26.6	20.8	32.2	24.3	19.2	21.1	36.1	27.0	20.2	30.9	24.0	19.2	31.3	23.2	44.6	25.4	32.7	43.7	26.7	15.3	22.0	13.1	9.1	19.0	15.5	10.2	11.9	17.2	16.1	12.4	20.6	16.5	15.4	21.8	17.1	16.6	17.0	16.9	17.3	22.8	16.1	13.3	18.1	29.6	19.8	15.6	18.5	19.2	20.7	17.5	17.1	25.9	15.2	19.9	19.4	33.8	15.9	35.5	20.2	32.4	17.2	16.9	28.5	22.9	22.7	14.0	17.5	16.3	19.1	33.0	29.7	18.7	16.1	16.4	13.3	19.4	14.1	12.3	19.0	19.6	15.9	13.9	17.1	41.9	25.4	44.6	32.4	22.8	38.4	31.3	35.9	34.7	20.3	29.9	39.5	38.4	37.0	32.7	17.9	23.2	43.7	26.7	22.2	27.2	19.9	33.8	20.8	26.9	24.3	25.0	25.2	21.1
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054170	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"			Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: , CAB068234: , CAB068235: , HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favourable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"	17.8	25.6	19.8	16.6	21.7	17.0	26.4	18.0	29.1	13.9	30.8	12.3	15.1	34.0	14.2	15.7	19.8	13.6	15.1	86.9	18.2	16.4	51.0	75.1	16.8	24.6	20.1	18.9	10.5	30.7	20.0	11.3	15.6	16.7	13.0	31.5	11.7	15.9	19.5	96.2	13.2	31.4	21.3	16.5	17.2	21.7	18.7	15.7	14.2	15.5	52.2	18.0	15.4	17.1	22.2	45.9	48.5	48.7	18.9	26.7	25.0	25.5	25.4	14.5	18.5	28.2	28.1	16.5	22.4	28.8	51.4	46.5	35.7	30.8	35.1	28.0	30.2	30.2	57.7	44.7	58.0	20.6	47.3	31.6	26.4	27.4	34.6	49.4	23.6	28.8	29.5	44.4	75.3	36.3	26.4	40.7	35.7	21.1	32.8	28.2	12.0	51.1	23.6	27.9	43.5	47.3	14.5	27.3	15.0	30.4	38.1	63.9	22.3	27.9	18.0	19.8	22.3	36.3	29.5	17.0	20.9	35.9	30.3	75.3	21.8	16.6	38.4	37.4	18.3	48.7	18.3	22.2	21.2	19.5	45.9	18.3	19.3	19.5	48.5	18.9	42.2	21.5	26.7	25.0	19.8	21.7	18.0	29.1	18.2	16.4	20.1	18.9	16.7	15.7
SDHC	"CYB560, cybL, PGL3"	ENSG00000143252	"Succinate dehydrogenase complex subunit C"	Q99643	1	161314257-161375340	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"																		"unprognostic (1.48e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.02e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.33e-1)"	"unprognostic (7.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-2)"	"unprognostic (1.29e-1)"	"prognostic favourable (2.20e-4)"	"unprognostic (9.14e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.19e-3)"	"unprognostic (3.77e-1)"	36.8	49.7	25.6	17.1	27.3	14.1	24.1	14.4	36.2	20.6	29.1	31.2	17.0	34.3	22.1	19.7	35.2	21.4	19.3	35.5	21.5	21.8	65.9	75.3	17.8	20.9	28.6	20.1	20.1	17.2	28.8	17.0	19.2	28.0	20.8	28.4	23.9	28.5	21.9	98.0	21.6	33.4	23.2	24.9	21.2	24.3	17.0	16.2	25.7	35.9	45.4	22.4	20.6	19.2	31.3	60.4	28.3	48.2	29.0	38.6	47.9	30.0	22.0	31.0	26.7	40.9	32.8	34.3	33.3	26.6	25.9	20.0	32.5	37.4	8.9	43.4	33.6	35.2	41.4	35.0	30.0	31.9	40.6	20.6	21.0	33.4	23.3	38.2	22.2	34.5	28.9	30.1	20.3	26.9	29.0	8.4	41.7	28.9	27.1	22.1	30.5	23.3	28.5	30.3	37.9	54.6	29.9	21.7	36.9	40.1	75.6	47.7	61.7	48.0	23.7	18.0	27.6	25.4	28.8	44.0	53.7	52.9	26.3	25.0	34.8	27.7	48.2	28.3	36.0	44.9	38.6	31.3	32.3	35.5	60.4	30.6	36.3	35.7	23.9	29.0	38.8	44.8	35.2	47.9	25.6	27.3	14.4	36.2	21.5	21.8	28.6	20.1	28.0	16.2
SDHD	"cybS, PGL, PGL1"	ENSG00000204370	"Succinate dehydrogenase complex subunit D"	O14521	11	112086773-112120013	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes, Disease mutation, FDA approved drug targets, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											HPA045727	Approved				"Intracellular and membrane"					"HPA045727: AB_10963114"	"unprognostic (9.13e-2)"	"unprognostic (3.51e-2)"	"unprognostic (4.47e-3)"	"unprognostic (4.21e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.98e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.83e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.80e-1)"	"prognostic favourable (1.99e-10)"	"unprognostic (5.14e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.56e-2)"	"unprognostic (7.51e-2)"	20.9	23.1	17.1	21.7	19.4	10.9	19.6	14.1	18.4	18.1	33.6	14.2	23.9	36.0	22.7	17.5	35.2	17.3	17.9	42.5	15.1	13.7	66.6	75.4	19.1	23.3	17.1	15.1	18.6	23.2	22.5	16.1	20.1	18.0	23.7	33.9	15.7	32.6	21.7	65.4	15.5	61.2	24.0	15.3	22.8	22.2	8.8	14.8	21.7	46.2	33.9	24.6	23.5	20.3	55.5	74.7	62.1	91.7	46.1	53.7	68.9	16.8	17.3	11.8	17.9	44.2	35.5	19.8	20.6	29.3	21.6	27.1	59.9	44.3	30.7	63.7	27.7	42.4	36.8	29.1	26.5	27.2	18.5	29.2	12.9	31.8	34.4	45.9	22.2	39.1	32.3	25.7	41.2	30.4	30.1	42.4	26.7	21.2	27.5	41.5	16.0	43.0	25.5	31.4	57.2	44.2	41.3	17.1	11.3	28.9	39.0	20.5	40.1	33.1	23.7	21.1	27.7	23.4	18.9	12.6	16.1	56.2	12.0	60.2	20.1	46.1	73.0	48.7	41.4	91.7	44.1	55.5	44.5	43.1	74.7	45.6	53.7	49.8	62.1	46.1	70.7	36.8	44.2	68.9	17.1	19.4	14.1	18.4	15.1	13.7	17.1	15.1	18.0	14.8
SETBP1	"KIAA0437, SEB"	ENSG00000152217	"SET binding protein 1"	Q9Y6X0	18	44680173-45068510	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"AF22: 9.3;Karpas-707: 37.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"memory B-cell: 4.9;naive B-cell: 7.5"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049022, HPA057259"	Uncertain		Supported	"Nucleoplasm,Nuclear bodies,Cytosol"				Nucleoplasm	"Nuclear bodies, Cytosol"	"HPA049022: , HPA057259: "	"unprognostic (1.25e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.97e-2)"	"unprognostic (4.63e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.91e-1)"	"unprognostic (3.57e-2)"	"unprognostic (3.49e-1)"	"unprognostic (2.01e-2)"	"unprognostic (2.71e-3)"	"unprognostic (6.52e-2)"	"prognostic favourable (6.34e-8)"	"unprognostic (2.18e-2)"	"unprognostic (2.29e-1)"	"unprognostic (6.06e-2)"	"unprognostic (7.81e-5)"	10.6	2.9	3.8	13.2	8.7	2.1	9.8	16.0	12.6	16.9	14.6	4.2	19.9	2.5	14.0	17.5	6.6	11.0	7.9	6.8	3.6	3.5	15.0	7.2	9.8	7.0	2.9	7.4	12.8	8.2	9.1	5.1	10.2	3.2	12.2	5.3	14.0	6.9	21.3	14.5	6.6	6.9	19.9	3.7	5.9	9.1	5.5	1.2	3.4	8.4	8.7	8.8	11.9	13.3	7.5	4.3	0.2	1.6	0.0	0.6	0.2	0.0	1.6	9.3	0.0	2.7	0.7	0.6	0.7	1.7	0.9	0.7	0.1	0.0	0.5	0.3	1.0	2.7	1.0	2.9	0.6	0.8	0.4	0.0	1.0	0.6	0.0	0.0	0.0	2.2	1.1	0.0	1.8	0.3	0.0	37.1	0.2	0.5	0.0	0.0	1.3	0.6	3.0	0.0	3.2	3.1	2.1	4.7	2.5	0.0	0.0	0.5	1.3	0.0	0.0	5.5	2.1	0.0	4.3	4.9	0.3	0.0	3.3	0.1	3.1	0.2	0.0	0.0	0.6	1.1	0.0	4.9	0.1	0.5	0.1	7.5	0.0	0.2	0.0	0.0	1.6	4.3	0.0	0.2	3.8	8.7	16.0	12.6	3.6	3.5	2.9	7.4	3.2	1.2
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019154	Approved		Supported	Nucleoplasm,Centrosome,Cytosol				"Nucleoplasm, Cytosol"	Centrosome	"HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favourable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"	25.6	17.5	16.0	14.0	16.7	11.4	24.9	29.7	16.0	27.9	22.6	17.9	21.3	15.1	28.2	18.8	21.7	20.5	17.5	19.6	15.3	11.5	21.0	22.0	20.1	16.0	17.2	13.3	30.5	25.0	30.0	28.9	30.6	14.2	27.8	17.4	18.4	23.1	22.8	39.7	18.2	23.4	27.6	13.9	21.7	19.3	17.6	18.4	38.8	35.0	13.9	18.1	29.0	24.1	3.6	3.6	3.4	1.8	2.9	4.7	1.3	8.5	11.3	30.7	8.8	12.7	19.6	17.3	15.0	16.5	20.2	25.4	6.9	2.0	14.2	4.5	13.0	14.1	17.2	6.7	21.5	12.3	9.7	9.8	11.3	7.9	12.6	17.1	7.7	8.9	11.4	9.9	14.6	14.6	11.0	13.1	11.9	4.5	10.1	4.9	16.0	7.1	13.2	15.6	13.9	9.7	3.7	19.0	11.3	14.0	2.6	9.3	7.0	10.0	11.0	17.1	7.9	4.3	9.9	19.7	13.7	12.3	11.1	6.7	11.3	0.8	1.8	1.8	3.2	1.1	3.7	2.2	3.3	2.6	3.6	3.6	4.0	4.7	3.4	2.9	1.3	2.9	4.3	1.3	16.0	16.7	29.7	16.0	15.3	11.5	17.2	13.3	14.2	18.4
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838008	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease mutation, Hypotrichosis, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"AF22: 19.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"				Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavourable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favourable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"	11.0	15.2	14.6	33.2	15.4	16.9	12.1	30.4	21.9	13.4	25.1	16.4	11.4	41.1	17.2	11.0	15.6	12.3	15.0	12.6	13.2	14.2	14.6	11.7	14.0	32.8	13.0	13.8	21.3	16.1	7.9	15.7	20.8	12.8	11.0	9.4	16.7	40.9	13.1	28.1	14.7	27.4	10.6	12.8	19.8	24.1	37.7	12.9	29.4	15.7	12.0	16.0	21.1	12.2	19.5	9.9	4.8	11.6	7.0	7.5	5.9	1.5	1.0	19.0	1.7	1.8	0.5	3.8	6.0	1.8	1.8	2.9	2.2	1.8	15.5	5.2	0.8	2.9	4.5	2.9	3.0	2.5	6.6	12.9	1.7	1.3	2.0	13.6	3.8	1.1	2.2	2.1	4.7	0.9	3.5	8.6	1.1	3.8	11.1	3.1	5.7	3.8	7.0	15.3	7.0	1.5	3.0	9.0	6.8	1.4	0.4	10.2	1.4	2.1	1.6	1.6	6.6	2.6	1.7	9.5	8.7	10.3	1.3	7.5	4.6	4.0	10.0	4.8	3.8	10.2	5.2	19.5	4.6	4.6	9.3	6.4	3.8	2.5	0.8	7.0	11.6	9.9	7.5	5.9	14.6	15.4	30.4	21.9	13.2	14.2	13.0	13.8	12.8	12.9
SMARCE1	BAF57	ENSG00000073584	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1"	Q969G3	17	40624962-40648864	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	Neurogenesis	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003916, CAB037318"	Supported		Supported	Nucleoplasm				Nucleoplasm		"CAB037318: AB_476780, HPA003916: AB_1857279"	"unprognostic (7.91e-2)"	"unprognostic (2.68e-2)"	"unprognostic (2.09e-2)"	"unprognostic (8.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.55e-2)"	"unprognostic (4.48e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-2)"	"unprognostic (2.04e-1)"	"unprognostic (9.80e-2)"	"unprognostic (5.93e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.27e-2)"	25.1	20.2	14.4	17.2	18.8	18.4	20.2	17.0	16.7	37.6	25.1	18.0	12.6	18.4	42.8	19.5	31.0	21.1	20.6	19.6	13.3	12.0	23.0	22.6	20.1	22.3	16.5	14.3	39.5	16.9	13.3	20.4	34.8	15.2	32.4	19.2	17.9	20.6	21.9	32.0	21.3	22.6	33.4	15.8	30.3	19.1	22.0	17.5	53.9	23.8	18.9	25.1	31.2	21.0	40.3	32.0	34.0	30.3	47.2	44.0	39.2	20.5	34.3	42.1	31.3	22.3	32.1	20.7	25.9	35.8	30.5	23.0	22.4	17.9	32.7	37.5	35.0	28.1	26.0	27.4	36.7	30.6	33.8	23.4	18.5	39.4	22.5	42.6	23.8	27.8	21.7	24.3	35.5	32.8	34.0	13.0	29.1	23.1	78.0	8.8	23.5	17.0	43.8	47.4	24.8	36.8	35.3	33.7	32.6	23.0	66.9	21.5	40.1	26.8	26.8	24.8	27.4	22.4	31.9	24.4	28.4	48.9	25.3	19.6	38.2	31.8	26.0	34.0	39.1	26.8	40.5	38.4	35.8	40.9	31.3	40.3	30.2	34.9	11.0	47.2	30.3	32.0	44.0	39.2	14.4	18.8	17.0	16.7	13.3	12.0	16.5	14.3	15.2	17.5
SPOP	"BTBD32, TEF2"	ENSG00000121067	"Speckle type BTB/POZ protein"	O43791	17	49598884-49678234	"Cancer-related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (1.96e-2)"	"unprognostic (1.43e-2)"	"unprognostic (8.83e-2)"	"unprognostic (3.23e-1)"	"unprognostic (2.15e-2)"	"unprognostic (4.51e-2)"	"prognostic unfavourable (6.88e-4)"	"unprognostic (1.89e-2)"	"unprognostic (7.20e-2)"	"unprognostic (1.17e-2)"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-3)"	"unprognostic (7.67e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.45e-2)"	"unprognostic (1.10e-2)"	"unprognostic (3.29e-1)"	22.0	16.5	22.5	16.9	24.9	7.9	18.6	39.8	26.9	27.5	59.5	25.0	25.1	15.2	36.2	21.2	35.4	25.2	17.2	22.7	22.7	18.8	17.0	20.2	19.1	19.6	20.9	21.4	26.0	18.5	15.1	28.5	18.2	23.2	38.8	23.5	21.8	22.8	49.5	29.2	15.2	24.1	45.1	18.4	18.8	28.4	10.5	26.8	28.6	26.4	14.3	23.3	35.6	22.3	43.2	55.6	59.6	43.1	40.7	58.4	50.8	14.2	16.1	18.6	7.0	20.9	22.3	12.6	18.7	19.4	24.8	25.8	32.7	15.7	23.6	35.9	17.0	11.5	21.0	13.6	29.7	43.6	23.3	27.3	16.4	18.6	24.0	17.9	22.3	16.7	17.5	19.4	21.1	25.3	28.2	24.3	16.7	13.9	32.9	16.5	4.9	19.6	18.7	27.0	30.4	13.4	8.5	27.9	13.0	11.8	6.0	15.4	23.1	18.7	22.1	26.9	18.7	21.1	15.4	24.3	20.3	20.6	15.8	16.1	13.5	57.0	41.8	50.6	36.2	37.1	36.1	42.4	40.6	39.2	55.6	43.2	58.4	45.3	59.6	40.7	43.1	37.2	36.0	50.8	22.5	24.9	39.8	26.9	22.7	18.8	20.9	21.4	23.2	26.8
STAT3	APRF	ENSG00000168610	"Signal transducer and activator of transcription 3"	P40763	17	42313324-42388568	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Diabetes mellitus, Disease mutation, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001671, CAB003859, HPA058603, CAB068241, CAB068242"	Supported		Supported	Nucleoplasm,Cytosol			220000	"Nucleoplasm, Cytosol"		"CAB003859: AB_347629, CAB068241: , CAB068242: , HPA001671: AB_1080102, HPA058603: "	"unprognostic (1.83e-2)"	"unprognostic (2.42e-1)"	"unprognostic (9.23e-3)"	"unprognostic (2.91e-1)"	"unprognostic (5.59e-3)"	"unprognostic (1.78e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.77e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.26e-1)"	"unprognostic (6.47e-3)"	"unprognostic (7.75e-3)"	"unprognostic (2.21e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.61e-1)"	44.6	30.7	23.2	34.4	27.5	35.3	49.3	15.7	23.5	25.1	31.5	18.4	21.7	20.5	33.2	27.4	36.4	32.7	34.0	82.9	20.1	14.7	34.5	90.0	45.7	45.5	26.0	11.1	40.6	32.1	18.6	27.9	24.6	27.6	28.9	21.8	24.3	29.3	22.9	53.4	28.4	28.6	49.7	25.1	41.4	29.4	15.4	25.7	16.8	38.0	31.2	28.8	40.4	53.1	10.8	13.7	69.7	20.2	13.9	21.7	26.7	16.6	31.7	14.0	13.8	30.0	28.6	10.2	19.6	24.9	17.0	16.6	8.3	16.2	5.2	19.4	19.4	25.5	12.7	20.0	13.9	43.0	8.7	36.2	19.3	17.1	22.2	8.8	23.6	44.6	19.7	13.5	19.6	23.0	22.2	16.6	11.2	11.8	32.6	8.8	8.1	0.0	7.2	37.4	7.7	26.9	21.7	12.9	8.4	22.6	53.6	8.1	28.1	13.3	19.4	26.3	13.5	15.6	16.0	25.7	20.0	4.4	16.3	9.4	11.6	26.2	19.4	24.9	21.7	20.2	17.3	10.8	16.0	16.8	13.7	10.4	16.6	15.8	69.7	13.9	18.7	7.5	12.0	26.7	23.2	27.5	15.7	23.5	20.1	14.7	26.0	11.1	27.6	25.7
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228435	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 11.7"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: "	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favourable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favourable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"	13.4	13.7	13.5	11.8	12.4	19.3	16.7	17.8	16.0	12.2	16.1	8.3	19.8	18.1	10.8	8.7	15.1	10.0	11.8	15.3	12.6	9.8	10.7	22.1	9.4	12.5	9.7	10.4	11.0	16.8	10.7	11.6	12.2	9.9	12.2	5.3	11.9	16.0	12.2	49.2	16.8	18.0	7.7	7.6	16.9	15.5	59.8	7.5	11.8	12.4	14.5	19.0	11.4	9.8	2.7	1.9	11.7	6.3	1.9	1.8	0.5	21.1	10.2	7.8	14.7	7.4	6.7	16.5	10.3	10.8	9.7	10.4	8.3	14.8	13.9	11.5	10.8	13.7	7.6	15.9	3.0	25.9	18.7	14.2	0.6	10.5	15.9	14.2	23.8	12.2	11.6	7.5	11.1	9.7	26.5	19.1	5.5	15.8	13.7	14.4	14.9	12.6	21.7	8.3	15.5	8.8	15.5	18.1	13.0	0.0	7.7	11.1	12.1	23.4	13.1	10.1	11.4	19.7	16.4	37.6	15.8	10.4	10.0	19.0	10.3	2.0	4.2	4.5	0.6	6.0	0.4	2.7	1.0	1.8	1.9	1.0	1.0	0.9	11.7	1.9	6.3	1.0	0.7	0.5	13.5	12.4	17.8	16.0	12.6	9.8	9.7	10.4	9.9	7.5
SUFU	"PRO1280, SUFUH, SUFUXL"	ENSG00000107882	"SUFU negative regulator of hedgehog signaling"	Q9UMX1	10	102503987-102633535	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		"Developmental protein"	"Cancer-related genes, Ciliopathy, Disease mutation, Joubert syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008700	Supported		Supported	Nucleoplasm				Nucleoplasm		"HPA008700: AB_1080125"	"unprognostic (1.55e-1)"	"unprognostic (4.00e-2)"	"unprognostic (5.14e-2)"	"unprognostic (1.33e-1)"	"unprognostic (4.69e-2)"	"unprognostic (5.68e-2)"	"unprognostic (3.69e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.64e-1)"	"unprognostic (3.15e-3)"	"unprognostic (9.60e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.72e-3)"	"unprognostic (1.82e-1)"	"unprognostic (1.44e-1)"	"unprognostic (5.10e-2)"	"unprognostic (3.82e-3)"	10.7	12.8	15.0	15.2	12.8	3.9	18.3	23.0	15.3	13.4	10.4	11.3	12.1	7.7	14.4	13.3	14.7	14.2	16.2	11.0	11.8	7.8	10.8	10.0	21.4	20.5	11.9	11.0	18.0	8.9	20.0	7.8	13.9	10.0	15.4	8.8	11.9	12.6	16.7	14.1	23.1	9.4	14.3	10.7	13.1	7.9	21.1	13.1	19.9	6.2	12.7	15.0	15.2	15.0	2.3	4.5	6.2	5.5	2.8	3.1	2.8	6.4	6.8	11.1	15.9	11.5	9.7	5.4	6.7	13.0	9.7	8.8	6.3	4.8	6.6	19.1	7.4	4.6	13.6	7.4	6.4	4.0	10.5	15.7	3.9	5.9	5.5	5.7	11.3	11.0	5.9	7.2	5.9	12.5	3.5	6.1	5.9	5.4	10.8	8.6	3.2	5.1	11.7	12.0	3.4	6.4	9.7	3.8	6.0	5.3	5.0	6.0	10.9	3.8	13.7	4.3	6.2	4.6	7.3	5.0	3.2	4.8	5.4	11.2	2.9	4.2	4.5	6.2	2.5	5.5	2.0	2.3	3.1	2.8	4.5	2.1	2.2	2.5	1.1	2.8	5.5	2.5	1.9	2.8	15.0	12.8	23.0	15.3	11.8	7.8	11.9	11.0	10.0	13.1
TERT	"EST2, hEST2, TCS1, TP2, TRT"	ENSG00000164362	"Telomerase reverse transcriptase"	O14746	5	1253147-1295069	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"		"DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase"	"Cancer-related genes, Disease mutation, Dyskeratosis congenita"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	6	"bone marrow: 3.4;lymphoid tissue: 12.0;testis: 5.0"	"Cell line enhanced"	"Detected in some"		"ASC TERT1: 61.2;fHDF/TERT166: 58.1;HBEC3-KT: 118.1;hTEC/SVTERT24-B: 74.6;LHCN-M2: 33.7;TIME: 96.1"	"Low cancer specificity"	"Detected in some"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in many"			"HPA054641, HPA065897"	Supported		Supported	"Nucleoplasm,Nuclear speckles,Cytosol"				Nucleoplasm	"Nuclear speckles, Cytosol"	"HPA054641: , HPA065897: "	"unprognostic (1.21e-2)"	"unprognostic (2.88e-2)"	"unprognostic (1.24e-3)"	"unprognostic (1.53e-1)"	"unprognostic (1.43e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-1)"	"unprognostic (6.91e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.59e-1)"	"unprognostic (9.16e-4)"	"unprognostic (8.84e-11)"	"unprognostic (1.92e-1)"	"unprognostic (2.15e-1)"		"unprognostic (3.35e-1)"	0.0	0.0	0.0	7.1	0.9	3.4	0.0	0.0	0.2	0.1	1.1	0.0	0.0	1.0	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	2.4	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.9	0.0	0.0	1.0	0.4	5.0	0.0	12.0	0.0	0.0	2.8	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	30.6	61.2	0.5	0.0	23.3	4.2	7.9	0.1	0.1	0.7	0.0	58.1	0.0	0.2	118.1	5.0	0.0	0.3	0.0	0.0	0.1	0.0	0.3	0.2	0.0	3.0	74.6	0.8	0.2	0.6	0.1	33.7	0.0	0.2	1.6	0.4	0.2	0.8	0.0	0.8	3.4	0.2	0.0	0.3	0.0	0.0	0.0	0.0	0.2	96.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.2	0.0	0.0	0.7	0.0	0.0	0.0
TGFBR2	"MFS2, TBR-ii, TBRII"	ENSG00000163513	"Transforming growth factor beta receptor 2"	P37173	3	30606502-30694142	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins"	"Apoptosis, Differentiation, Growth regulation"	"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB073537			Supported	"Plasma membrane"			560000	"Plasma membrane"		"CAB073537: "	"unprognostic (1.74e-1)"	"unprognostic (1.84e-2)"	"unprognostic (3.70e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.62e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.65e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.81e-2)"	"unprognostic (8.81e-2)"	"unprognostic (8.02e-2)"	91.8	24.6	6.7	24.6	10.3	7.3	88.3	3.6	7.3	36.5	42.6	9.8	18.6	13.2	42.6	23.3	36.2	28.4	42.6	73.5	6.9	5.2	32.6	21.9	52.6	75.7	12.6	3.7	22.2	26.0	17.4	10.3	24.2	9.9	35.2	17.5	27.9	22.5	19.5	34.9	17.0	31.3	37.2	12.0	68.7	26.8	15.4	8.2	19.3	40.9	16.8	26.9	48.0	82.0	5.3	6.8	20.0	6.6	1.4	19.7	3.9	2.4	14.4	0.9	0.0	53.4	80.5	2.4	12.5	17.6	4.3	4.3	3.2	13.3	0.3	45.3	16.8	5.0	0.6	18.3	7.2	1.0	1.3	1.4	1.6	16.2	22.8	2.2	11.8	69.5	16.3	18.6	18.0	46.7	0.2	0.0	65.8	0.2	2.3	1.6	0.4	5.8	2.0	5.8	0.3	23.2	5.8	0.0	0.9	3.7	1.0	3.5	0.0	2.4	60.3	21.2	5.2	9.6	4.7	0.4	0.0	2.0	12.7	2.5	8.5	6.9	2.9	20.0	3.5	3.0	3.2	4.0	5.4	4.2	2.6	5.3	19.7	9.1	12.6	1.4	6.6	6.8	1.2	3.9	6.7	10.3	3.6	7.3	6.9	5.2	12.6	3.7	9.9	8.2
TMEM127	"FLJ20507, FLJ22257"	ENSG00000135956	"Transmembrane protein 127"	O75204	2	96248516-96265994	"Cancer-related genes, Disease related genes, Predicted membrane proteins"			"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (5.15e-3)"	"unprognostic (2.67e-1)"	"unprognostic (1.72e-2)"	"unprognostic (6.51e-2)"	"unprognostic (5.82e-2)"	"unprognostic (2.05e-1)"	"prognostic unfavourable (6.59e-4)"	"unprognostic (6.73e-2)"	"unprognostic (4.25e-1)"	"unprognostic (1.06e-2)"	"unprognostic (7.50e-2)"	"unprognostic (2.17e-1)"	"prognostic favourable (6.69e-5)"	"unprognostic (3.59e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.15e-2)"	"unprognostic (3.65e-2)"	27.6	27.8	16.4	18.7	22.6	31.8	26.1	20.2	40.6	22.9	27.2	18.7	27.3	22.2	24.8	18.9	29.3	18.2	24.2	45.6	15.6	16.5	29.3	43.3	22.9	19.8	14.8	13.1	23.4	26.2	50.7	23.7	21.6	21.4	20.5	21.5	26.5	29.8	31.5	18.7	24.0	41.8	24.4	11.2	28.5	20.0	12.7	12.8	19.6	22.4	19.3	26.9	26.1	22.3	2.4	4.5	14.7	6.7	1.5	3.4	2.9	11.8	16.0	8.5	13.1	37.8	19.2	15.8	15.6	28.0	16.6	15.3	15.8	16.9	7.4	22.9	30.6	19.1	9.8	14.4	11.7	14.9	7.7	12.9	7.7	15.4	24.4	10.9	23.3	23.2	20.6	20.6	15.3	18.8	7.9	16.0	16.9	13.5	7.1	6.9	11.6	17.3	6.7	10.7	11.0	18.6	20.4	9.6	10.1	11.4	27.2	13.0	10.1	11.7	22.0	27.8	15.9	24.0	10.7	12.2	11.7	5.9	18.5	12.9	14.7	4.1	6.5	7.9	3.1	6.7	3.4	2.1	2.3	3.3	4.5	2.4	1.8	2.4	14.7	1.5	5.3	2.7	1.6	2.9	16.4	22.6	20.2	40.6	15.6	16.5	14.8	13.1	21.4	12.8
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687550	"Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 102.6"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: , HPA051244: , HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favourable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavourable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	18.5	11.1	6.0	28.6	6.8	9.0	17.5	2.5	7.3	18.5	14.6	6.8	8.3	9.7	20.3	15.0	25.3	16.7	22.6	8.1	5.0	3.8	10.6	20.8	11.2	26.0	6.6	3.1	33.8	13.8	4.9	6.0	22.8	6.9	16.5	14.5	9.9	15.3	16.1	12.5	24.6	14.0	12.8	6.2	24.2	12.0	14.1	6.9	102.6	13.2	23.5	31.2	16.9	15.0	15.2	19.6	2.2	14.1	11.0	11.3	8.2	19.2	35.6	19.4	14.0	9.1	10.8	20.6	6.9	15.6	19.2	24.3	1.0	9.9	45.3	31.5	13.6	42.5	28.2	19.1	18.0	10.1	18.9	18.3	20.0	16.9	27.4	0.4	9.5	13.7	22.2	9.3	25.7	18.8	0.9	1.7	9.8	34.2	30.7	22.4	19.6	0.7	59.7	13.7	15.7	14.3	21.3	11.6	20.0	22.8	15.4	5.9	26.7	1.7	24.3	23.0	7.6	0.3	11.6	11.9	8.7	19.5	6.0	2.3	19.4	0.8	13.3	2.2	9.1	14.1	11.1	15.2	9.4	10.2	19.6	14.5	9.9	10.8	1.7	11.0	11.9	17.9	11.3	8.2	6.0	6.8	2.5	6.4	5.0	3.8	6.6	3.1	6.9	6.9
TP63	"EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L"	ENSG00000073282	"Tumor protein p63"	Q9H3D4	3	189631416-189897279	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease mutation, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skeletal muscle: 83.2;skin 1: 54.2"	"Group enriched"	"Detected in some"	5	"HaCaT: 23.3;HBEC3-KT: 44.6;hTCEpi: 33.8;hTERT-HME1: 32.3;RT4: 49.0"	"Group enriched"	"Detected in many"	11	"cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2"	"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000083, HPA006288, HPA006289, HPA007009, HPA007010"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336"	"prognostic favourable (1.07e-4)"	"unprognostic (1.30e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.02e-1)"	"unprognostic (4.38e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.78e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.09e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.87e-5)"	"unprognostic (1.86e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.74e-3)"	2.9	0.1	0.2	0.7	0.1	0.0	7.2	0.1	0.2	9.5	0.1	0.1	5.7	0.0	0.3	8.0	33.7	0.3	0.0	0.2	0.1	0.1	0.4	0.1	1.2	0.2	0.1	0.2	0.1	0.1	0.0	0.3	7.8	0.8	9.6	0.0	0.3	9.0	7.8	83.2	54.2	0.1	2.7	0.6	0.1	0.1	1.2	0.0	9.0	0.4	36.7	26.1	9.6	19.2	3.7	1.3	3.0	0.9	1.2	1.2	0.2	0.6	1.2	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.1	0.0	23.3	0.0	44.6	0.0	0.3	0.0	0.5	0.3	0.1	0.0	0.0	0.1	0.0	33.8	0.0	32.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	49.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	6.8	0.1	0.3	0.1	0.0	0.2	2.0	0.4	1.1	0.9	0.5	0.7	3.7	1.2	1.0	0.4	1.7	0.8	0.7	3.0	1.2	0.9	1.3	0.8	0.2	0.2	0.1	0.1	0.2	0.1	0.1	0.1	0.2	0.8	0.0
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol				Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: "	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavourable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favourable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favourable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"	10.4	13.6	15.8	8.8	26.8	13.6	11.4	32.1	28.3	12.7	10.8	22.6	7.9	9.1	14.6	12.3	10.9	12.4	9.7	17.6	13.0	12.1	13.1	9.4	11.6	10.2	12.5	15.1	21.2	12.1	15.9	19.5	15.8	21.1	11.8	12.6	13.1	11.6	10.4	20.0	13.8	11.2	14.2	12.4	13.7	10.6	36.2	14.9	10.5	16.2	8.6	14.2	10.9	11.1	2.8	3.1	4.8	7.0	4.9	7.1	2.6	6.1	7.3	10.0	8.2	10.3	9.8	18.8	8.3	13.4	8.7	8.6	12.4	7.2	14.4	3.6	15.8	16.0	11.7	8.4	8.9	6.9	6.2	4.6	14.5	10.1	12.3	6.7	6.2	10.5	6.4	11.1	13.6	10.0	8.0	7.9	9.9	11.4	6.0	5.8	13.7	6.1	7.3	18.9	8.1	3.9	8.1	5.0	7.7	9.7	6.1	4.8	11.0	4.0	10.3	14.3	8.6	8.5	5.6	4.4	9.8	14.0	8.1	4.0	6.3	4.1	4.4	4.8	6.5	7.0	7.1	1.9	3.6	5.7	3.1	2.8	5.9	5.3	1.7	4.9	3.2	1.8	5.7	2.6	15.8	26.8	32.1	28.3	13.0	12.1	12.5	15.1	21.1	14.9
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047465-2089487	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol				Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: "	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favourable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"	13.9	11.9	16.9	12.4	20.0	10.9	13.2	35.1	26.9	20.5	17.0	19.4	17.9	14.0	20.1	12.2	13.0	18.6	15.0	14.0	13.3	8.8	11.8	9.8	12.7	10.1	13.8	14.7	21.1	16.1	20.0	18.1	10.6	14.6	13.8	10.8	16.7	22.9	19.6	31.7	14.5	13.2	13.5	11.4	12.9	16.6	21.4	12.9	14.1	20.1	11.3	10.9	18.0	14.0	4.7	5.6	7.7	4.9	3.6	7.0	3.7	7.2	11.6	16.1	18.2	19.2	16.2	13.6	17.4	11.9	13.1	11.2	13.9	13.8	10.9	15.5	14.3	12.0	9.6	12.6	9.8	8.3	15.8	10.3	22.5	5.7	13.2	12.8	12.5	19.1	8.0	10.6	7.9	12.3	10.0	9.8	11.6	14.4	15.2	3.8	16.7	11.4	24.2	17.6	13.9	5.3	6.5	12.2	23.1	24.8	16.4	8.8	15.0	9.5	19.4	13.8	9.4	12.3	8.8	21.9	21.8	21.8	5.7	5.2	16.3	6.2	4.9	5.4	7.0	4.7	6.7	4.4	4.4	4.1	5.6	4.7	3.1	4.8	7.7	3.6	3.7	1.5	3.2	3.7	16.9	20.0	35.1	26.9	13.3	8.8	13.8	14.7	14.6	12.9
TSHR	LGR3	ENSG00000165409	"Thyroid stimulating hormone receptor"	P16473	14	80954989-81146302	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Congenital hypothyroidism, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"thyroid gland: 158.0"	"Group enriched"	"Detected in some"	17	"MOLT-4: 18.1;SCLC-21H: 18.7;U-266/70: 9.2;U-266/84: 4.7"	"Cancer enriched"	"Detected in some"	116	"thyroid cancer: 100.4"	"Not detected"	"Not detected"			"Cell type enriched"	"Detected in some"	5	"T-reg: 9.9"	"Lineage enriched"	"Detected in many"	5	"T-cells: 9.9"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			CAB000473	Approved				"Intracellular and membrane"					"CAB000473: AB_2303782"	"unprognostic (3.36e-3)"	"unprognostic (1.31e-3)"	"unprognostic (1.02e-2)"	"unprognostic (4.17e-6)"	"unprognostic (3.01e-3)"	"unprognostic (1.85e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.66e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.70e-1)"	"unprognostic (7.11e-3)"	"unprognostic (5.08e-7)"	"unprognostic (1.32e-1)"	"unprognostic (7.40e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.66e-1)"	0.1	0.2	0.1	0.2	0.4	0.3	0.2	0.1	0.3	0.1	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.3	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.4	0.1	0.0	0.1	0.1	0.1	0.3	0.3	0.5	0.1	0.0	0.8	0.2	0.0	0.1	0.3	0.1	0.0	0.2	0.2	0.1	0.1	0.1	27.3	158.0	0.2	0.4	0.1	0.1	1.8	0.8	1.3	0.3	0.1	9.9	0.1	0.3	0.2	0.6	0.4	0.1	0.1	0.3	0.1	0.1	0.0	0.1	0.3	0.4	0.6	0.2	0.1	0.2	0.7	0.0	0.1	0.2	0.1	0.3	0.6	0.3	0.0	0.2	0.3	0.3	0.1	0.1	0.2	0.1	0.3	0.6	0.1	0.4	18.1	0.4	0.4	0.2	0.6	0.2	0.7	0.0	0.4	18.7	0.3	0.1	0.2	0.2	0.3	0.0	0.2	0.5	0.4	0.5	0.2	9.2	4.7	0.4	0.2	0.2	0.3	0.6	0.2	0.2	0.2	0.1	0.2	1.0	0.8	0.5	0.1	1.8	0.3	0.2	1.3	0.1	0.3	0.8	9.9	0.1	0.1	0.4	0.1	0.1	0.1	0.1	0.1	0.0	0.5	0.1
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141008-10152220	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 53.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB005430, HPA031631, HPA031632"	Uncertain		Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB005430: AB_2241850, HPA031631: , HPA031632: "	"prognostic unfavourable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavourable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favourable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"	13.8	17.4	18.1	29.2	18.4	24.3	15.4	25.8	21.4	13.3	19.8	19.3	14.5	15.9	15.1	13.6	16.4	14.3	18.9	10.5	17.1	18.5	13.7	16.3	14.6	27.9	13.5	12.3	15.2	22.5	13.8	14.6	18.8	12.8	15.1	16.6	12.5	21.8	13.7	14.8	14.0	22.3	13.4	17.0	22.6	16.2	17.9	11.2	39.2	16.9	11.5	29.3	15.4	19.1	5.4	3.9	8.0	4.1	4.4	4.3	1.7	6.7	6.5	14.3	8.8	13.3	10.3	53.6	5.9	8.5	7.6	9.0	7.6	8.4	23.8	8.1	8.0	5.8	13.2	8.3	9.4	11.4	12.0	18.5	10.5	10.5	12.6	16.3	14.8	10.3	9.5	10.1	12.8	8.7	16.4	18.1	7.5	12.2	15.5	12.0	9.6	8.3	19.7	12.6	11.9	9.3	17.4	5.4	17.9	12.5	6.7	7.2	13.2	20.7	7.5	7.6	10.1	7.0	9.3	12.9	26.4	38.0	8.4	19.5	6.9	2.6	4.1	3.3	3.8	2.5	3.6	4.1	2.9	4.3	3.9	5.4	2.5	2.7	8.0	4.4	3.2	2.4	3.1	1.7	18.1	18.4	25.8	21.4	17.1	18.5	13.5	12.3	12.8	11.2
WAS	"IMD2, THC, WASP, WASPA"	ENSG00000015285	"Wiskott-Aldrich syndrome"	P42768	X	48676596-48691427	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 30.7;lymphoid tissue: 55.9"	"Cell line enhanced"	"Detected in some"		"Daudi: 21.3;HMC-1: 45.7;MOLT-4: 19.4;NB-4: 21.1;RPMI-8226: 26.0;U-266/70: 24.2;U-937: 24.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"eosinophil: 20.3"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002022, CAB004290"	Enhanced		Approved	"Plasma membrane,Cytosol"			320000	"Plasma membrane"	Cytosol	"CAB004290: AB_628445, HPA002022: AB_1080581"	"unprognostic (1.43e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.36e-2)"	"prognostic favourable (4.95e-4)"	"unprognostic (9.89e-2)"	"prognostic favourable (3.78e-4)"	"unprognostic (5.12e-3)"	"unprognostic (7.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.40e-2)"	"unprognostic (3.60e-1)"	"prognostic unfavourable (5.58e-6)"	"unprognostic (2.24e-1)"	"unprognostic (2.37e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.71e-1)"	7.6	4.0	4.9	28.9	7.8	30.7	3.3	2.0	5.1	2.7	4.4	5.9	0.5	4.8	2.4	5.6	3.7	4.5	4.4	3.0	4.6	4.1	4.1	5.0	12.6	29.9	7.6	1.3	2.6	2.2	0.7	2.6	5.4	6.0	3.2	3.2	3.5	5.4	1.9	1.4	2.2	14.3	3.7	12.8	55.9	4.1	1.7	7.3	53.2	2.8	1.4	33.2	5.8	2.5	2.1	3.5	20.3	5.3	2.1	3.2	2.0	0.2	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	21.3	0.0	0.0	0.7	0.0	0.0	0.0	12.2	0.1	18.8	0.2	0.0	0.2	9.6	45.7	0.0	0.0	0.0	0.0	0.0	0.2	13.1	0.0	2.1	19.4	21.1	0.1	0.1	16.9	0.0	26.0	0.0	0.0	0.1	0.2	0.3	0.2	0.2	0.1	19.2	0.1	0.0	0.1	0.3	0.0	24.2	11.8	14.9	0.1	24.4	0.0	1.8	4.6	20.3	3.0	5.0	2.2	1.8	2.3	2.5	3.5	2.1	2.1	2.3	18.1	2.1	5.3	1.8	3.2	2.0	4.9	7.8	2.0	5.1	4.6	4.1	7.6	1.3	6.0	7.3
WRN	"RECQ3, RECQL2"	ENSG00000165392	"Werner syndrome RecQ like helicase"	Q14191	8	31033801-31173769	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028661	Approved		Supported	"Nuclear speckles"				"Nuclear speckles"		"HPA028661: AB_10602255"	"unprognostic (8.73e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.51e-3)"	"unprognostic (3.85e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.27e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.53e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.00e-2)"	"unprognostic (2.66e-1)"	10.1	9.2	5.6	8.5	6.6	15.6	11.1	10.7	7.3	14.2	8.0	7.7	7.7	5.5	24.4	8.8	7.6	9.7	6.9	7.0	5.9	4.0	5.1	7.7	7.2	6.7	8.2	5.3	12.0	9.9	7.8	28.1	8.5	7.0	8.6	7.8	8.3	10.8	7.8	7.7	10.2	7.0	12.1	14.9	8.9	8.3	10.4	7.3	11.8	7.9	6.3	9.3	10.8	8.7	3.9	2.7	1.3	1.9	2.9	6.2	1.6	6.4	6.3	13.1	8.3	7.8	12.5	8.3	7.3	7.1	8.9	9.3	4.0	3.9	15.1	6.7	7.3	3.3	8.1	5.2	13.4	4.2	6.9	15.4	6.0	3.3	9.8	9.1	5.7	9.1	5.8	8.5	10.2	8.6	24.3	9.6	8.2	4.1	18.9	4.4	11.2	4.6	10.9	9.9	6.0	3.7	7.0	2.8	7.5	8.8	5.0	6.9	3.5	4.5	13.7	9.7	6.0	5.0	6.1	2.5	2.7	19.0	7.2	7.2	6.6	1.2	1.9	1.3	3.3	1.9	6.2	3.9	3.8	3.3	2.7	3.5	2.5	3.2	0.5	2.9	0.8	2.0	2.8	1.6	5.6	6.6	10.7	7.3	5.9	4.0	8.2	5.3	7.0	7.3
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"Wilms tumor 1"	P19544	11	32387775-32435630	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 69.0;fallopian tube: 34.5;ovary: 53.4"	"Cell line enhanced"	"Detected in some"		"HEL: 13.2;HMC-1: 17.0;K-562: 11.9;NB-4: 31.9;THP-1: 15.3"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"pons and medulla: 0.5"	"Low region specificity"	"Detected in single"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000327: AB_2304486, HPA035717: , HPA053848: "	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"	10.3	0.0	0.2	1.8	0.6	0.0	0.2	0.2	0.5	20.3	1.5	0.2	3.7	0.0	69.0	9.3	0.4	34.5	0.8	2.1	0.9	0.0	5.3	0.2	0.8	0.5	0.2	0.2	53.4	0.2	0.0	0.2	6.9	0.3	0.9	0.0	0.2	0.2	4.2	0.2	0.0	0.4	23.7	0.2	14.6	0.0	24.5	0.2	0.2	0.3	0.2	0.2	1.3	4.1	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.0	0.1	0.1	0.0	0.0	6.1	0.0	0.0	0.0	4.6	13.2	0.0	1.1	3.7	8.8	17.0	0.0	0.0	2.7	0.0	0.0	11.9	0.1	2.7	0.0	7.7	31.9	0.7	3.7	1.1	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	15.3	0.1	0.0	2.3	0.0	0.3	0.0	0.0	0.0	0.1	2.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.2	0.6	0.2	0.5	0.9	0.0	0.2	0.2	0.3	0.2
XPA	"XP1, XPAC"	ENSG00000136936	"XPA, DNA damage recognition and repair factor"	P23025	9	97674909-97697357	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000155, HPA056856"	Supported		Approved	"Nucleoplasm,Cytokinetic bridge"				Nucleoplasm	"Cytokinetic bridge"	"CAB000155: , HPA056856: "	"unprognostic (8.76e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.60e-1)"	"unprognostic (2.30e-2)"	"unprognostic (4.17e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.26e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.97e-3)"	"unprognostic (9.55e-3)"	"prognostic favourable (4.28e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.56e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.17e-1)"	18.7	17.5	20.1	17.1	21.0	10.6	17.4	26.8	20.8	20.3	25.2	17.2	11.7	20.6	25.5	15.4	18.9	15.0	19.5	12.9	17.2	15.3	24.9	24.2	14.8	16.7	18.6	17.5	17.2	14.5	23.0	23.1	12.8	17.7	20.3	13.6	16.4	16.1	21.7	43.3	16.3	22.2	27.5	17.1	16.2	25.1	6.4	15.8	15.7	31.5	11.9	21.6	22.0	16.4	22.2	23.4	12.7	15.8	19.7	21.6	11.3	23.4	5.5	8.2	10.1	10.1	9.8	5.7	6.4	10.1	11.7	7.9	14.3	19.7	13.2	6.2	7.0	11.8	6.5	7.7	9.9	9.0	13.1	10.4	12.0	7.9	11.0	12.2	12.6	8.5	8.4	5.4	5.6	13.0	14.3	10.4	6.4	7.3	15.9	14.8	5.6	9.2	16.3	17.6	11.2	18.6	9.2	11.6	11.6	9.1	7.1	8.3	10.2	7.5	8.1	4.1	10.2	16.2	13.8	18.4	14.7	8.3	10.2	8.8	8.0	6.0	13.3	12.7	16.2	13.1	18.7	19.5	17.7	15.6	13.5	22.2	21.6	18.6	1.5	19.7	15.8	23.4	18.3	11.3	20.1	21.0	26.8	20.8	17.2	15.3	18.6	17.5	17.7	15.8
XPC	"RAD4, XPCC"	ENSG00000154767	"XPC complex subunit, DNA damage recognition and repair factor"	Q01831	3	14145147-14178783	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009932, HPA035707, HPA069673"	Supported		Enhanced	"Nucleoplasm,Plasma membrane"				Nucleoplasm	"Plasma membrane"	"CAB009932: AB_2241587, HPA035707: , HPA069673: "	"unprognostic (7.46e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.50e-2)"	"unprognostic (3.01e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.54e-2)"	"unprognostic (1.97e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.50e-1)"	"unprognostic (7.13e-3)"	"unprognostic (4.39e-2)"	"unprognostic (2.07e-1)"	"prognostic favourable (4.14e-7)"	"unprognostic (1.59e-1)"	"unprognostic (7.88e-2)"	"unprognostic (7.62e-2)"	"prognostic favourable (2.46e-4)"	20.2	17.1	14.2	24.0	30.2	8.4	21.4	16.1	19.3	22.3	18.9	20.8	27.5	18.0	24.6	18.3	16.9	24.9	25.1	12.4	16.2	14.4	24.6	23.4	19.9	21.1	33.4	15.2	35.0	20.9	35.4	26.7	28.0	22.1	20.9	15.9	16.7	17.6	30.3	22.4	30.5	23.6	17.7	22.6	23.3	15.9	12.9	30.6	18.5	25.7	12.4	20.8	22.4	22.3	10.9	7.0	34.6	8.8	8.8	12.2	6.1	4.4	11.5	13.0	8.3	19.5	13.5	44.0	11.1	32.0	10.8	8.4	4.2	5.4	15.0	4.9	13.5	5.6	8.5	17.8	8.9	6.0	7.3	7.9	12.2	7.7	17.3	5.9	15.1	19.1	21.1	14.3	28.8	12.8	10.9	8.1	12.0	9.4	4.9	5.7	7.7	7.8	6.2	5.9	12.0	13.6	13.4	2.8	10.1	12.1	10.1	8.0	10.6	4.8	20.0	4.2	11.4	6.3	5.1	18.7	13.6	8.9	10.0	7.0	15.1	12.0	8.2	9.4	9.8	6.3	9.6	10.7	11.2	9.6	7.0	10.9	12.2	8.7	34.6	8.8	8.8	6.7	9.2	6.1	14.2	30.2	16.1	19.3	16.2	14.4	33.4	15.2	22.1	30.6