Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"
ACVR2A	"ACTRII, ACVR2"	ENSG00000121989	"Activin A receptor type 2A"	P27037	2	147844517-147930826	"Cancer-related genes, Enzymes, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HHSteC: 20.5;RH-30: 17.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046997	Approved		Approved	Cytosol				Cytosol		"HPA046997: AB_10970077"	"unprognostic (4.55e-2)"	"unprognostic (2.26e-2)"	"unprognostic (2.09e-1)"	"unprognostic (7.34e-3)"	"unprognostic (2.75e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.41e-3)"	"unprognostic (8.73e-3)"	"unprognostic (1.30e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.52e-1)"	"prognostic favourable (1.62e-4)"	"unprognostic (1.16e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.95e-1)"	"unprognostic (3.99e-2)"	12.0	6.0	13.6	8.2	9.9	3.8	10.7	14.5	14.2	10.2	14.1	4.7	9.7	10.4	9.3	9.9	13.6	7.6	17.7	5.6	10.0	9.0	9.0	10.3	7.5	4.7	5.9	10.6	7.6	9.8	8.6	15.9	10.6	7.3	12.2	9.1	7.6	12.2	12.0	19.6	29.5	17.8	13.8	5.4	6.5	9.3	11.0	6.4	1.5	9.5	6.9	6.8	13.5	11.8	0.7	3.0	0.5	3.6	7.7	4.6	1.4	1.3	1.5	9.8	3.6	5.8	3.7	4.0	3.0	3.6	5.2	9.1	4.2	5.9	0.0	2.7	4.8	4.6	8.9	4.4	6.7	1.0	5.4	0.6	2.7	7.3	20.5	0.6	0.7	6.2	5.6	3.3	6.7	3.9	1.4	2.5	3.5	3.4	0.3	0.5	11.0	2.6	0.1	17.1	0.9	4.2	8.3	9.7	5.5	2.5	3.1	3.7	1.9	1.0	3.0	4.8	5.7	4.5	2.1	0.7	0.2	1.8	3.0	0.3	3.8	0.4	3.0	0.5	1.2	3.6	0.5	0.3	4.6	2.1	2.3	0.7	3.0	0.7	0.1	7.7	3.1	3.0	0.4	1.4	13.6	9.9	14.5	14.2	10.0	9.0	5.9	10.6	7.3	6.4
AMER1	"FAM123B, FLJ39827, RP11-403E24.2, WTX"	ENSG00000184675	"APC membrane recruitment protein 1"	Q5JTC6	X	64185117-64205744	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 15.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"NK-cell: 2.0"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065214, HPA065265"	Approved		Supported	"Nuclear bodies,Vesicles,Plasma membrane"				"Nuclear bodies"	"Vesicles, Plasma membrane"	"HPA065214: , HPA065265: "	"unprognostic (1.56e-2)"	"unprognostic (8.85e-2)"	"unprognostic (6.86e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.75e-1)"	"unprognostic (6.31e-2)"	"unprognostic (3.43e-1)"	"unprognostic (4.69e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.19e-2)"	"unprognostic (2.89e-1)"	3.0	3.4	3.0	2.8	5.6	2.3	3.0	8.8	4.9	6.8	4.7	3.1	7.8	3.3	9.8	11.3	6.9	5.2	2.4	3.5	3.0	3.4	4.2	7.1	2.8	2.6	4.5	1.6	15.5	8.1	5.1	3.9	2.0	6.3	4.5	3.2	6.8	7.0	5.3	9.0	4.8	3.7	6.6	2.9	3.7	5.1	1.4	4.3	2.4	3.4	6.5	3.4	4.3	5.7	0.4	0.2	0.0	0.3	2.0	1.0	0.1	2.9	2.2	5.6	4.5	2.2	2.1	4.5	1.4	1.2	2.0	1.3	7.1	1.0	5.6	1.8	2.9	4.1	12.0	3.9	2.0	2.6	2.4	3.4	4.4	4.5	1.6	7.2	0.9	3.0	5.2	1.5	3.1	1.2	5.2	5.7	1.1	3.4	4.7	3.9	15.1	4.3	11.3	9.2	4.1	0.9	0.9	2.5	3.8	3.5	4.8	1.9	1.5	2.1	0.7	2.5	5.8	6.5	1.8	2.9	2.0	4.3	1.1	8.2	0.0	0.0	0.3	0.0	0.4	0.1	0.0	0.4	0.0	0.4	0.0	0.3	1.0	0.0	0.0	2.0	0.0	0.2	0.9	0.1	3.0	5.6	8.8	4.9	3.0	3.4	4.5	1.6	6.3	4.3
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC, WNT signaling pathway regulator"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 40.9"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA013349	Supported									"HPA013349: AB_1844913"	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"	7.2	5.4	40.9	6.4	21.7	8.5	6.3	19.1	39.7	6.8	7.1	10.3	2.0	6.6	6.3	3.9	8.4	5.0	5.5	7.4	37.9	12.9	6.9	6.2	6.7	5.6	23.6	20.7	7.6	4.6	13.8	7.2	5.5	39.1	5.9	6.9	4.0	4.0	4.9	7.0	6.1	8.8	8.1	19.1	6.2	5.4	5.3	20.6	3.6	6.5	2.7	6.2	6.2	3.9	3.8	3.0	12.9	2.9	3.0	3.4	1.1	8.3	7.7	12.8	9.3	10.6	8.8	5.2	13.5	6.4	7.5	8.9	6.1	6.8	16.1	13.1	17.2	6.8	13.1	11.0	12.4	9.6	8.9	12.2	11.1	4.6	5.2	6.1	6.7	7.4	7.6	12.7	8.4	10.4	15.0	5.6	10.9	5.8	7.0	3.1	4.6	2.7	6.0	15.9	7.8	6.9	10.6	13.0	7.8	12.8	5.0	5.5	6.9	5.0	16.6	15.3	7.4	15.0	10.2	4.4	6.6	6.3	8.5	11.4	8.5	10.4	2.9	5.0	3.4	1.4	2.9	3.1	1.8	2.1	2.3	3.8	2.9	2.8	12.9	3.0	2.5	3.0	1.6	1.1	40.9	21.7	19.1	31.4	37.9	12.9	23.6	20.7	39.1	20.6
ARID1A	"B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1"	ENSG00000117713	"AT-rich interaction domain 1A"	O14497	1	26693236-26782110	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005456, CAB016334"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB016334: AB_673396, HPA005456: AB_1078205"	"unprognostic (2.83e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.89e-2)"	"prognostic unfavourable (4.18e-4)"	"unprognostic (3.02e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.34e-1)"	"unprognostic (9.69e-2)"	"unprognostic (7.76e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.62e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.66e-1)"	"unprognostic (6.54e-2)"	18.6	18.4	17.4	24.9	17.0	33.8	27.8	23.6	19.1	20.3	23.7	21.7	23.9	15.8	24.1	17.3	23.2	20.6	21.9	15.5	14.8	12.8	13.7	15.9	18.8	35.6	20.3	19.2	24.1	23.9	27.5	15.8	19.3	17.2	16.5	16.4	18.9	21.4	23.1	22.6	20.6	20.7	18.4	15.4	25.9	19.5	16.5	19.8	57.3	24.8	14.2	24.5	24.4	20.4	4.3	5.3	7.4	3.3	4.7	5.1	3.5	18.9	18.0	25.6	26.6	7.4	7.1	12.0	8.9	7.7	12.2	8.7	13.2	12.8	26.8	7.8	11.5	11.5	22.2	9.8	14.3	33.2	8.7	22.8	11.7	8.8	6.1	33.7	7.3	8.2	7.0	14.4	10.3	10.5	27.2	30.0	7.9	9.0	28.4	13.1	27.0	8.4	29.7	16.9	15.2	7.6	12.8	23.9	19.7	15.6	13.2	10.7	3.9	19.2	18.4	13.1	12.7	12.2	14.4	14.3	18.8	12.3	8.0	21.6	11.6	0.4	3.3	2.9	4.0	2.9	5.1	4.3	3.2	4.9	3.1	4.3	4.0	4.4	7.4	4.7	2.8	5.3	1.5	3.5	17.4	17.0	23.6	19.1	14.8	12.8	20.3	19.2	17.2	19.8
ARID1B	"6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R"	ENSG00000049618	"AT-rich interaction domain 1B"	Q8NFD5	6	156777374-157210779	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016511, HPA075291"	Approved		Supported	Nucleoplasm				Nucleoplasm		"HPA016511: AB_1845008, HPA075291: "	"prognostic unfavourable (1.04e-4)"	"unprognostic (9.82e-2)"	"unprognostic (1.73e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.47e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.73e-2)"	"unprognostic (2.89e-1)"	"unprognostic (1.18e-1)"	"prognostic unfavourable (4.16e-4)"	"unprognostic (2.53e-1)"	"unprognostic (5.33e-2)"	"unprognostic (1.07e-3)"	"unprognostic (2.46e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.53e-1)"	"unprognostic (1.16e-1)"	18.3	15.0	20.2	18.8	20.9	25.8	19.3	42.1	32.8	20.0	17.4	26.3	21.7	15.3	23.0	14.2	18.6	20.7	15.9	16.8	20.4	11.3	14.2	10.6	17.0	18.3	19.4	16.7	30.2	18.5	47.4	29.2	12.2	17.7	17.7	13.3	24.0	20.0	20.2	30.6	27.3	17.8	21.7	14.9	21.1	15.0	10.7	24.6	24.0	23.8	13.3	26.3	23.5	21.0	9.5	11.9	5.6	3.0	2.7	5.6	1.6	7.0	10.9	16.1	21.9	13.2	12.2	11.0	7.5	9.9	9.8	9.8	9.6	10.3	22.4	4.7	12.8	9.0	13.7	12.3	9.7	22.5	9.7	16.2	11.0	11.4	9.3	13.5	11.9	13.8	9.9	14.9	13.3	13.6	19.0	17.5	7.0	8.3	15.6	15.2	8.1	5.8	35.6	6.9	12.1	6.7	13.2	14.8	18.9	15.1	15.9	8.8	10.7	21.2	13.9	12.4	13.2	11.4	14.7	12.1	10.8	28.7	10.8	16.2	16.6	5.6	3.0	2.5	5.4	2.4	5.0	6.8	4.7	3.8	2.3	9.5	4.0	5.6	5.5	2.7	2.6	11.9	4.6	1.6	20.2	20.9	42.1	32.8	20.4	11.3	19.4	16.7	17.7	24.6
ARID2	"BAF200, DKFZp686G052, FLJ30619, KIAA1557"	ENSG00000189079	"AT-rich interaction domain 2"	Q68CP9	12	45729665-45908040	"Cancer-related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA063044			Supported	"Nucleoplasm,Plasma membrane"				Nucleoplasm	"Plasma membrane"	"HPA063044: "	"unprognostic (8.41e-2)"	"unprognostic (1.03e-1)"	"unprognostic (4.02e-2)"	"unprognostic (3.94e-2)"	"unprognostic (4.15e-2)"	"prognostic favourable (5.75e-4)"	"unprognostic (1.26e-2)"	"unprognostic (9.71e-2)"	"unprognostic (9.04e-2)"	"unprognostic (5.57e-2)"	"unprognostic (1.34e-1)"	"unprognostic (2.47e-1)"	"unprognostic (1.12e-2)"	"unprognostic (9.21e-2)"	"unprognostic (3.02e-1)"	"unprognostic (2.00e-1)"	"unprognostic (6.53e-2)"	9.0	7.9	7.1	14.6	7.2	14.0	11.8	15.7	8.8	10.2	11.4	8.2	17.9	6.4	12.2	10.7	11.5	8.8	10.6	8.2	7.4	5.8	8.7	6.9	10.2	13.0	9.6	3.8	12.2	10.7	18.4	15.1	10.3	7.5	9.9	8.1	10.1	9.7	20.6	8.6	13.5	12.6	12.5	7.3	10.2	9.0	30.9	11.0	33.3	11.5	8.2	11.2	10.0	10.0	2.1	5.3	10.5	4.9	3.1	4.4	1.3	5.4	7.8	14.0	6.1	6.0	4.2	7.6	3.8	5.4	5.3	5.0	11.1	5.6	10.5	7.0	5.2	6.6	11.3	6.4	7.7	4.6	5.4	13.9	8.6	5.4	4.1	10.9	6.4	3.4	4.9	6.7	10.7	5.4	11.7	10.9	4.7	7.1	15.6	7.8	8.3	4.2	12.1	10.0	10.1	5.1	9.0	7.6	9.7	6.2	7.2	6.0	10.9	21.9	6.4	5.7	6.9	3.8	4.9	7.3	6.0	29.3	4.4	28.7	4.0	10.5	1.7	4.2	4.1	2.2	4.3	1.7	3.7	4.4	2.4	2.1	3.6	3.3	2.4	3.1	4.9	5.3	3.1	1.3	7.1	7.2	15.7	8.8	7.4	5.8	9.6	3.8	7.5	11.0
ASXL1	KIAA0978	ENSG00000171456	"Additional sex combs like 1, transcriptional regulator"	Q8IXJ9	20	32358330-32439319	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation, Ubl conjugation pathway"	"Chromatin regulator, Repressor"	"Cancer-related genes, Craniosynostosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA064156			Approved	Nucleoplasm,Nucleoli				"Nucleoplasm, Nucleoli"		"HPA064156: "	"unprognostic (1.49e-1)"	"unprognostic (5.97e-2)"	"unprognostic (8.36e-2)"	"prognostic unfavourable (2.86e-4)"	"unprognostic (6.69e-2)"	"prognostic favourable (9.16e-4)"	"unprognostic (2.01e-3)"	"unprognostic (2.89e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-1)"	"unprognostic (4.32e-2)"	"unprognostic (3.21e-2)"	"unprognostic (1.84e-3)"	"unprognostic (5.47e-2)"	"unprognostic (1.90e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.06e-1)"	24.3	19.6	19.0	35.0	18.2	39.0	24.7	28.3	23.8	32.4	22.7	17.7	16.9	15.6	32.4	22.2	14.3	20.5	21.6	17.9	19.7	10.7	21.2	25.2	27.3	26.7	20.3	14.7	28.1	27.1	21.2	16.3	19.8	18.2	20.6	16.4	16.6	17.4	23.3	25.5	18.2	21.8	21.8	12.2	28.2	19.7	32.1	23.0	47.4	26.8	15.8	29.0	23.2	35.3	9.8	3.1	1.3	0.8	1.7	14.6	1.9	22.6	13.2	20.7	11.4	9.5	11.8	18.0	15.2	13.0	26.6	19.7	39.1	14.6	21.4	9.8	18.7	15.8	17.4	14.6	21.7	32.0	9.4	34.2	20.9	21.4	8.5	14.2	14.2	13.1	9.8	18.5	13.9	14.6	16.5	11.6	12.3	6.9	19.4	11.5	5.0	15.2	11.3	24.7	9.2	10.9	10.9	9.5	14.9	27.6	9.2	12.1	13.1	10.1	15.1	28.3	24.7	13.0	16.9	13.6	14.5	15.8	14.3	37.9	10.8	0.0	0.8	1.3	4.4	0.7	3.5	9.8	5.2	5.6	0.7	5.8	5.8	5.9	0.9	1.7	0.7	3.1	14.6	1.9	19.0	18.2	28.3	23.8	19.7	10.7	20.3	14.7	18.2	23.0
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222484-108369102	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 47.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Enhanced	Nucleoplasm,Vesicles				"Nucleoplasm, Vesicles"		"CAB000102: , HPA067142: "	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"	8.3	10.9	12.7	26.5	19.3	16.8	9.4	17.7	14.4	10.9	8.5	10.9	8.8	6.0	11.2	11.4	6.9	9.5	9.2	9.6	12.4	8.5	7.7	9.5	10.1	33.4	19.6	6.7	20.5	20.7	15.7	29.2	8.8	14.5	9.1	7.9	7.2	15.1	9.8	6.2	8.4	16.5	10.6	23.4	22.6	8.9	6.1	17.9	19.5	10.7	5.1	26.9	10.7	10.7	13.7	6.1	13.5	12.5	7.6	18.5	4.4	2.6	3.8	7.5	4.0	9.8	14.3	1.9	6.0	6.7	3.5	5.8	4.7	6.3	9.4	8.9	4.8	4.0	5.7	5.0	5.4	7.5	3.3	8.5	4.7	4.7	5.1	10.2	9.2	9.2	3.1	5.2	10.2	7.2	8.2	6.4	6.8	1.9	7.0	9.4	6.1	3.8	5.5	5.2	14.8	3.9	5.4	5.1	6.3	6.9	3.2	10.3	4.9	5.8	11.3	8.6	4.8	4.9	5.6	4.3	4.5	47.4	5.7	11.3	9.6	13.5	5.7	3.8	14.9	5.3	10.4	11.1	10.5	11.3	2.7	13.7	18.5	17.9	10.8	7.6	12.5	6.1	5.3	4.4	12.7	19.3	17.7	14.4	12.4	8.5	19.6	6.7	14.5	17.9
ATRX	"JMS, MRX52, RAD54, XH2, XNP"	ENSG00000085224	"ATRX, chromatin remodeler"	P46100	X	77504878-77786269	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"DNA damage, DNA repair, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001906, CAB009372, HPA064684, CAB068176"	Supported		Supported	"Nuclear bodies"				"Nuclear bodies"		"CAB009372: AB_2061023, CAB068176: , HPA001906: AB_1078249, HPA064684: "	"unprognostic (1.77e-2)"	"unprognostic (1.55e-1)"	"unprognostic (6.65e-2)"	"unprognostic (4.37e-2)"	"unprognostic (1.67e-1)"	"unprognostic (9.69e-2)"	"unprognostic (8.11e-2)"	"unprognostic (1.15e-2)"	"unprognostic (6.04e-2)"	"unprognostic (2.35e-2)"	"unprognostic (1.09e-1)"	"unprognostic (5.80e-2)"	"unprognostic (5.14e-3)"	"unprognostic (1.50e-1)"	"unprognostic (6.19e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.24e-1)"	16.4	16.6	24.5	18.9	29.3	24.3	16.3	48.2	26.4	20.6	15.4	7.1	18.9	10.2	20.2	17.1	13.5	13.8	13.4	15.1	22.9	15.8	16.6	12.2	15.9	18.6	21.1	21.3	25.4	18.3	35.7	28.1	15.9	20.2	18.4	12.6	7.1	15.8	16.5	20.1	14.1	13.5	22.3	15.3	20.1	15.6	6.5	22.4	23.7	19.8	12.7	16.5	19.9	21.1	21.9	12.8	21.5	11.5	14.6	17.7	5.7	15.1	24.4	25.1	16.8	12.5	16.8	8.9	13.1	12.1	9.7	11.5	8.3	13.3	21.0	13.5	13.9	13.5	20.0	7.8	16.6	11.8	13.1	12.7	29.0	6.1	6.8	16.5	4.4	11.1	7.7	14.3	13.7	17.1	14.9	24.2	12.1	11.9	12.7	8.6	18.1	18.9	20.6	34.6	10.8	9.5	20.3	14.3	24.7	26.4	10.4	8.7	8.3	8.4	23.6	13.7	21.3	15.4	9.2	7.2	22.3	18.9	10.1	13.1	12.1	21.3	6.9	13.8	17.7	8.7	17.1	19.2	16.3	13.7	5.1	21.9	16.8	13.5	21.5	14.6	11.5	12.8	12.8	5.7	24.5	29.3	48.2	26.4	22.9	15.8	21.1	21.3	20.2	22.4
AXIN1	PPP1R49	ENSG00000103126	"Axin 1"	O15169	16	287440-352673	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB012987	Approved		Supported	Nucleoli,Vesicles				"Nucleoli, Vesicles"		"CAB012987: AB_2533178"	"unprognostic (3.81e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.90e-1)"	"unprognostic (7.64e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.06e-1)"	"prognostic unfavourable (3.38e-5)"	"unprognostic (1.23e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.56e-1)"	"unprognostic (4.58e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.57e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.94e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.03e-1)"	10.8	8.3	13.7	18.9	17.1	28.1	21.0	26.4	13.6	10.4	15.8	12.7	9.4	17.3	12.6	8.5	14.1	10.7	12.7	11.0	11.5	7.7	9.8	9.6	13.6	13.4	15.6	10.6	13.3	17.7	11.1	11.9	8.4	13.9	11.4	10.2	9.6	13.9	9.5	17.7	16.9	17.6	18.9	9.6	15.1	15.2	9.6	14.6	17.5	12.7	7.5	14.5	11.9	22.9	1.8	1.4	5.5	1.1	3.6	10.4	2.4	9.4	13.8	7.3	12.9	5.5	5.1	15.5	6.4	5.9	8.9	7.7	20.2	11.1	14.7	9.9	6.6	13.7	11.5	10.0	4.0	14.4	18.8	9.5	11.5	14.7	9.4	10.9	10.6	5.0	17.5	9.2	11.3	5.8	23.7	8.1	4.0	25.4	11.7	7.6	16.8	8.4	22.2	6.7	20.4	6.7	5.6	16.8	10.3	12.2	13.7	20.1	9.0	13.9	6.6	8.9	9.5	10.2	9.2	9.4	9.2	18.0	4.2	7.3	8.7	1.4	1.1	5.5	10.4	0.9	9.5	1.8	3.0	7.0	0.8	1.6	3.2	4.3	3.2	3.6	0.7	1.4	3.0	2.4	13.7	17.1	26.4	13.6	11.5	7.7	15.6	10.6	13.9	14.6
AXIN2	"DKFZp781B0869, MGC126582"	ENSG00000168646	"Axin 2"	Q9Y2T1	17	65528563-65561647	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 13.3;CACO-2: 24.7;Hep G2: 36.9"	"Cancer enhanced"	"Detected in all"		"colorectal cancer: 33.4"	"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"naive CD4 T-cell: 5.1"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012283, CAB017783"	Approved		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"				"Nucleoplasm, Plasma membrane"	Cytosol	"CAB012283: AB_2290204, CAB017783: "	"unprognostic (1.31e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.48e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.57e-2)"	"unprognostic (8.84e-3)"	"prognostic favourable (6.58e-4)"	"unprognostic (1.98e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.45e-2)"	"unprognostic (2.10e-1)"	"unprognostic (2.74e-1)"	"unprognostic (1.25e-1)"	7.4	10.1	9.0	7.0	8.9	0.9	5.2	8.2	13.1	16.5	12.2	8.7	10.5	7.2	29.0	7.7	6.5	18.6	6.9	7.3	7.9	5.7	3.5	2.5	15.2	3.4	5.3	10.3	14.7	3.9	3.2	5.8	18.2	10.6	14.8	15.2	7.8	4.6	9.8	12.4	14.9	7.5	18.0	4.8	6.9	14.6	6.8	9.0	27.6	11.3	3.6	3.8	11.8	8.7	4.1	0.0	4.4	0.0	1.9	5.1	0.8	0.0	6.6	13.3	0.2	4.8	2.0	5.9	0.2	0.6	0.4	0.8	24.7	2.4	0.4	0.8	3.8	0.2	2.7	0.0	0.9	1.1	1.5	0.0	1.1	36.9	0.5	0.0	0.0	1.2	1.0	1.0	0.3	1.1	0.1	0.6	0.6	0.1	6.4	0.0	2.6	0.3	4.6	0.7	0.0	1.2	0.1	4.1	2.7	0.2	0.1	2.3	0.4	0.1	3.0	2.6	4.8	3.7	0.8	0.0	1.3	1.7	1.2	0.3	1.2	4.4	0.0	0.0	0.3	0.0	0.8	1.0	2.3	0.4	0.0	4.1	5.1	0.8	0.0	1.9	0.0	0.0	0.0	0.8	9.0	8.9	8.2	13.1	7.9	5.7	5.3	10.3	10.6	9.0
B2M		ENSG00000166710	Beta-2-microglobulin	P61769	15	44711477-44718877	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	Immunity		"Amyloidosis, Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"THP-1: 175.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002572, HPA006361"	Enhanced		Enhanced	"Golgi apparatus,Plasma membrane,Cytosol"	"Intracellular and membrane"		3200000000	"Golgi apparatus, Plasma membrane"	Cytosol	"CAB002572: AB_563434, HPA006361: AB_1078278"	"unprognostic (9.45e-2)"	"unprognostic (5.63e-2)"	"unprognostic (3.02e-1)"	"unprognostic (8.14e-2)"	"unprognostic (1.18e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.69e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.44e-3)"	"unprognostic (2.02e-2)"	"unprognostic (4.77e-2)"	"unprognostic (2.39e-1)"	"unprognostic (5.25e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.17e-2)"	127.2	50.9	24.2	109.2	29.8	131.1	85.2	11.8	23.1	70.5	111.4	29.1	43.3	79.1	72.7	74.7	80.5	36.8	112.8	73.6	26.0	23.1	109.7	140.3	191.2	172.1	42.2	18.8	54.8	42.7	7.8	40.5	91.9	33.1	78.7	128.9	53.5	121.5	40.9	45.7	94.1	178.5	55.1	56.7	272.8	52.5	30.0	29.5	108.0	97.7	71.5	131.6	135.9	73.5	138.9	74.9	341.3	132.8	128.8	215.8	323.7	33.1	14.7	1.4	8.3	54.6	73.6	52.1	22.0	44.9	35.8	60.9	19.1	77.4	15.8	31.1	21.4	29.3	5.5	9.8	17.2	110.7	13.0	60.2	89.2	22.1	41.6	33.7	36.1	37.2	9.1	11.0	11.8	24.4	15.3	2.2	39.6	17.7	13.8	89.0	2.4	31.4	16.8	36.0	100.3	31.2	137.5	5.8	2.1	23.0	18.7	25.9	6.2	175.3	48.5	70.3	7.8	92.6	42.9	41.0	93.8	29.5	68.5	111.3	33.6	221.2	90.4	210.9	126.8	132.8	125.9	138.9	171.7	141.1	58.9	109.4	137.0	167.5	341.3	128.8	106.5	74.9	215.8	323.7	24.2	29.8	11.8	23.1	26.0	23.1	42.2	18.8	33.1	29.5
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401013-52410350	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	"Chromatin regulator, Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: , HPA055560: "	"unprognostic (1.52e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.96e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.41e-3)"	"unprognostic (8.53e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.15e-1)"	"unprognostic (4.64e-3)"	"unprognostic (3.30e-3)"	"prognostic favourable (3.29e-7)"	"unprognostic (6.37e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.92e-1)"	13.8	17.6	35.6	14.7	33.3	37.3	13.5	21.8	50.4	12.5	17.0	16.3	11.5	12.4	14.7	14.6	21.2	12.1	15.7	16.4	41.5	15.5	16.6	19.0	14.9	15.2	19.4	27.6	16.9	16.3	30.0	11.1	14.8	19.6	14.4	14.9	15.6	17.9	14.6	24.8	40.5	13.9	14.5	10.0	16.1	13.3	37.3	14.7	18.6	15.3	12.9	16.0	14.1	11.7	5.5	8.4	11.3	5.0	3.0	8.5	3.9	15.3	17.5	21.2	18.0	20.5	13.2	23.9	15.2	19.7	24.7	19.2	21.1	14.4	22.0	7.6	21.2	12.5	22.3	24.5	15.8	21.8	21.1	27.3	37.0	21.8	19.1	25.6	24.3	19.7	32.9	27.3	14.7	19.7	23.3	19.5	18.6	13.3	30.3	35.1	23.9	21.3	13.1	17.2	21.7	15.2	24.9	8.1	26.1	18.7	5.4	22.2	15.3	35.4	21.1	22.4	20.6	26.8	28.2	29.6	38.9	31.5	24.4	27.0	26.4	3.4	5.0	7.4	8.5	3.9	4.0	5.0	6.8	6.9	3.3	5.5	4.9	6.4	11.3	3.0	3.1	8.4	6.0	3.9	35.6	33.3	21.8	50.4	41.5	15.5	19.4	27.6	19.6	14.7
BCOR	"FLJ20285, KIAA1575"	ENSG00000183337	"BCL6 corepressor"	Q6W2J9	X	40049815-40177329	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Repressor"	"Cancer-related genes, Disease mutation, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA056308, HPA073591"			Enhanced	Nucleoplasm				Nucleoplasm		"HPA056308: , HPA073591: "	"unprognostic (2.75e-2)"	"unprognostic (2.83e-1)"	"unprognostic (2.45e-1)"	"unprognostic (9.26e-2)"	"unprognostic (1.55e-1)"	"unprognostic (9.80e-3)"	"prognostic unfavourable (1.30e-5)"	"unprognostic (3.82e-3)"	"unprognostic (6.86e-2)"	"unprognostic (1.86e-1)"	"unprognostic (4.08e-2)"	"unprognostic (1.18e-1)"	"unprognostic (3.91e-3)"	"unprognostic (6.83e-2)"	"unprognostic (9.57e-2)"	"unprognostic (2.63e-1)"	"unprognostic (1.55e-1)"	9.1	12.8	8.7	8.7	10.5	20.6	13.3	11.5	12.0	10.0	12.6	22.7	11.9	7.8	11.1	13.9	13.6	10.4	8.6	13.0	7.1	5.4	11.2	13.3	11.4	15.2	12.9	8.4	19.8	13.6	19.7	11.9	12.5	10.7	13.2	8.2	13.7	11.1	16.5	28.8	13.6	10.3	12.9	8.6	11.4	11.5	9.8	15.8	18.4	16.0	11.4	13.5	13.8	25.5	6.5	7.3	7.6	7.1	8.2	6.8	11.8	12.9	8.6	17.5	21.4	2.0	1.5	3.0	4.4	7.0	5.6	4.6	3.6	5.2	11.8	5.2	8.2	12.1	28.5	3.7	5.0	20.6	25.9	13.1	13.2	14.1	3.4	10.6	7.6	2.6	5.5	6.2	3.6	7.6	33.7	28.5	6.9	8.3	24.0	22.2	17.2	13.4	11.7	18.1	13.3	10.3	8.2	12.5	22.7	9.2	8.2	6.9	8.8	23.4	6.2	6.1	7.7	8.9	4.9	16.9	13.1	12.3	5.3	9.7	9.3	7.6	5.0	4.5	6.8	6.1	4.3	6.5	4.7	3.9	7.3	5.5	4.7	4.8	1.1	8.2	7.1	3.1	5.5	11.8	8.7	10.5	11.5	12.0	7.1	5.4	12.9	8.4	10.7	15.8
BCORL1	"CXorf10, FLJ11362"	ENSG00000085185	"BCL6 corepressor like 1"	Q5H9F3	X	129981107-130058083	"Cancer-related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Repressor"	"Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"AN3-CA: 20.0;HAP1: 30.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031775, HPA031777, HPA068568"	Uncertain		Approved	"Nucleoplasm,Plasma membrane"				Nucleoplasm	"Plasma membrane"	"HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: "	"unprognostic (8.07e-2)"	"unprognostic (2.78e-2)"	"unprognostic (7.09e-2)"	"prognostic unfavourable (2.20e-5)"	"unprognostic (4.58e-1)"	"unprognostic (1.68e-3)"	"unprognostic (1.96e-3)"	"unprognostic (5.56e-3)"	"unprognostic (2.39e-1)"	"unprognostic (8.02e-2)"	"unprognostic (4.46e-2)"	"unprognostic (2.04e-1)"	"prognostic unfavourable (5.00e-4)"	"unprognostic (9.18e-2)"	"unprognostic (2.60e-2)"	"unprognostic (3.09e-1)"	"unprognostic (1.41e-2)"	7.5	7.9	7.7	5.2	9.1	9.8	9.1	19.8	10.5	8.7	8.3	10.7	8.1	5.4	9.2	5.4	5.8	9.3	4.2	6.9	8.4	4.5	7.5	4.7	6.7	5.3	7.6	5.9	11.4	8.9	13.4	15.0	28.9	7.5	8.1	4.5	6.0	6.5	8.4	6.0	6.5	6.0	8.8	5.3	7.7	6.6	26.1	8.1	6.8	10.3	2.2	5.1	6.7	8.5	1.2	1.6	3.5	1.3	0.8	1.3	0.7	2.2	5.4	12.7	20.0	7.5	5.4	3.5	2.9	3.5	3.8	4.4	6.5	1.4	1.0	6.6	5.9	1.3	30.1	1.2	3.6	2.2	4.4	10.3	2.6	2.2	3.7	2.5	3.0	3.3	2.5	7.5	0.4	4.6	4.9	10.6	2.5	1.3	3.8	7.8	3.5	3.8	8.1	5.1	1.4	2.1	0.3	2.1	7.2	1.6	0.4	1.9	4.4	3.9	3.8	3.1	4.0	3.8	2.8	3.4	6.2	1.6	2.1	5.3	1.4	0.1	1.3	2.8	1.3	0.2	1.0	1.2	0.9	0.8	1.6	1.0	0.6	0.7	3.5	0.8	0.5	0.7	0.2	0.7	7.7	9.1	19.8	10.5	8.4	4.5	7.6	5.9	7.5	8.1
BIRC3	"API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49"	ENSG00000023445	"Baculoviral IAP repeat containing 3"	Q13489	11	102317450-102339403	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 46.0;lymphoid tissue: 46.3"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 37.5;Daudi: 33.0;HDLM-2: 31.2;hTERT-HME1: 32.8;U-266/70: 22.0;U-266/84: 18.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"memory B-cell: 32.9;naive B-cell: 32.9"	"Group enriched"	"Detected in many"	10	"B-cells: 32.9;T-cells: 17.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002317	Enhanced	Approved	Supported	Nucleoplasm,Cytosol				"Nucleoplasm, Cytosol"		"HPA002317: AB_1846748"	"prognostic favourable (3.60e-4)"	"unprognostic (2.89e-1)"	"prognostic favourable (9.35e-4)"	"unprognostic (3.28e-2)"	"prognostic unfavourable (7.28e-4)"	"unprognostic (5.83e-3)"	"unprognostic (2.23e-1)"	"unprognostic (3.88e-3)"	"unprognostic (9.62e-2)"	"unprognostic (1.29e-1)"	"prognostic unfavourable (3.03e-4)"	"unprognostic (3.21e-1)"	"prognostic unfavourable (6.66e-6)"	"unprognostic (6.42e-2)"	"unprognostic (6.23e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.85e-2)"	6.9	3.3	1.4	43.9	2.3	5.1	5.4	0.5	2.0	5.3	13.1	0.5	2.8	6.8	2.9	3.7	8.4	3.9	13.9	6.0	2.2	1.3	10.8	12.5	21.8	46.3	2.8	1.2	3.4	7.0	1.1	14.5	0.9	2.2	8.7	6.2	1.1	9.2	4.7	2.2	5.5	46.0	7.3	3.0	34.9	15.9	3.2	2.7	34.2	3.0	4.1	34.0	12.6	6.2	32.9	0.8	2.0	2.6	2.5	17.1	2.8	6.3	5.1	0.0	0.1	0.1	0.7	0.6	0.5	4.3	0.6	0.7	0.9	37.5	33.0	17.0	0.3	3.6	0.0	0.9	2.1	31.2	0.1	0.1	1.5	0.2	6.5	0.5	0.7	0.7	4.6	2.1	32.8	0.1	0.1	0.0	0.8	0.0	2.2	0.3	0.1	0.2	0.0	0.3	1.6	8.5	3.3	0.0	0.1	0.5	0.5	0.3	1.6	0.3	1.7	7.2	0.7	0.4	6.5	22.0	18.8	11.6	1.3	1.8	0.8	2.0	0.9	0.4	1.4	2.2	2.5	32.9	10.7	3.5	0.8	32.9	7.5	2.2	0.5	2.5	2.6	0.3	17.1	2.8	1.4	2.3	0.5	2.0	2.2	1.3	2.8	1.2	2.2	2.7
BLM	"BS, RECQ2, RECQL3"	ENSG00000197299	"Bloom syndrome RecQ like helicase"	P54132	15	90717327-90816165	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"lymphoid tissue: 36.7"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005689	Approved		Supported	Nucleoplasm,Cytosol				"Nucleoplasm, Cytosol"		"HPA005689: AB_1845372"	"unprognostic (2.77e-1)"	"unprognostic (3.82e-3)"	"unprognostic (4.03e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.75e-2)"	"unprognostic (9.89e-2)"	"unprognostic (6.12e-5)"	"unprognostic (2.82e-2)"	"unprognostic (4.55e-3)"	"unprognostic (5.24e-3)"	"unprognostic (1.80e-3)"	"unprognostic (9.12e-2)"	"unprognostic (1.55e-15)"	"unprognostic (6.53e-3)"	"unprognostic (6.55e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.83e-2)"	1.8	0.4	3.1	11.4	1.5	5.5	0.6	4.7	2.6	0.7	1.9	0.9	0.5	1.4	1.2	1.1	2.9	0.4	1.3	1.0	2.3	2.4	0.9	0.5	2.0	7.7	2.8	0.2	0.9	0.4	0.0	1.2	3.6	0.5	0.7	2.5	0.7	7.8	0.0	1.7	0.6	2.8	0.5	1.9	6.7	1.4	4.9	0.5	36.7	0.6	3.1	9.3	1.4	0.7	7.4	1.2	4.3	1.6	4.6	5.0	1.6	5.4	7.8	8.7	5.1	0.0	0.4	5.5	4.1	1.2	4.7	5.1	6.8	3.8	14.1	2.6	1.1	9.1	13.4	3.7	6.1	8.5	9.9	14.7	8.4	2.2	0.0	14.1	7.3	0.0	0.0	4.7	2.4	3.3	12.7	4.4	4.9	3.4	10.6	7.8	9.3	1.7	10.8	16.4	5.4	1.1	9.8	6.5	6.1	3.3	4.4	2.6	3.1	11.6	1.8	3.4	6.3	3.5	8.7	3.2	13.1	14.7	1.9	10.0	5.8	2.5	1.0	4.3	3.1	1.2	4.8	7.4	2.8	3.8	1.2	4.3	2.0	2.2	0.8	4.6	1.6	1.2	5.0	1.6	3.1	1.5	4.7	1.7	2.3	2.4	2.8	0.2	0.5	0.5
BMPR1A	"ACVRLK3, ALK3, CD292"	ENSG00000107779	"Bone morphogenetic protein receptor type 1A"	P36894	10	86756601-86932838	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019398	Approved		Approved	Cytosol				Cytosol		"CAB019398: "	"unprognostic (1.36e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.34e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.05e-3)"	"unprognostic (9.34e-2)"	"prognostic unfavourable (8.93e-4)"	"unprognostic (3.64e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (9.24e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.07e-1)"	8.9	7.0	9.4	7.9	12.4	0.9	10.7	14.1	9.2	19.4	20.6	10.9	7.7	6.2	16.3	12.3	8.4	10.9	10.8	11.0	7.7	6.1	8.2	4.6	7.4	2.9	7.3	7.6	16.1	10.6	10.0	14.0	7.4	8.5	12.8	9.3	10.9	12.6	14.2	8.4	11.3	9.8	16.5	12.2	3.4	12.1	7.8	9.2	0.3	19.4	7.8	5.7	16.0	11.4	1.8	1.1	3.6	0.8	0.9	1.4	0.3	7.5	3.8	14.7	12.5	7.7	5.0	2.6	7.6	8.0	4.5	5.2	6.5	6.7	2.3	3.5	9.7	8.1	6.5	8.3	6.6	2.5	3.7	2.9	3.6	10.7	4.1	4.0	20.4	4.4	3.5	6.0	4.4	0.0	4.5	1.6	5.2	3.2	2.6	3.2	8.0	1.8	0.0	5.8	0.0	9.2	7.2	1.5	4.8	8.5	4.3	5.1	7.3	2.0	3.8	3.2	5.2	6.6	7.0	0.4	7.0	2.9	2.8	2.7	2.6	2.0	0.8	0.6	1.4	0.5	0.9	1.8	1.4	1.2	0.3	1.5	1.0	1.1	3.6	0.9	0.6	1.1	0.7	0.3	9.4	12.4	14.1	9.2	7.7	6.1	7.3	7.6	8.5	9.2
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1, DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in all"	5	"dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"				"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: "	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"	4.8	4.3	6.0	9.6	11.3	15.3	5.1	12.9	10.6	5.4	9.2	3.4	6.8	4.3	5.4	5.5	9.1	5.5	3.3	6.5	6.6	5.3	4.2	7.7	4.9	13.0	7.5	5.9	5.1	4.7	4.2	11.0	5.3	10.5	4.1	10.4	3.7	5.4	7.4	7.3	8.3	6.7	5.5	9.2	5.9	5.1	17.6	7.0	10.9	15.6	7.3	14.6	5.5	5.6	2.0	9.1	9.7	12.7	1.4	1.3	10.7	15.5	25.2	13.9	11.1	2.3	5.2	13.6	18.3	7.9	15.4	14.7	15.3	12.1	35.9	3.4	7.0	18.0	18.9	10.2	25.9	16.4	13.8	16.9	19.8	13.2	0.5	30.1	14.7	1.4	1.7	23.2	7.4	7.9	25.4	15.4	14.5	10.3	25.2	9.9	7.6	6.7	17.4	29.3	14.7	5.7	15.1	9.6	10.3	14.1	4.7	6.9	12.4	13.9	5.2	13.8	11.2	17.8	19.1	7.2	17.6	27.6	11.1	17.9	14.4	4.6	12.7	1.8	1.3	4.0	1.3	1.1	1.3	1.0	9.1	2.0	1.2	1.3	9.7	1.4	1.5	1.4	0.4	10.7	6.0	11.3	12.9	10.6	6.6	5.3	7.5	5.9	10.5	7.0
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2, DNA repair associated"	P51587	13	32315474-32400266	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 23.2;testis: 16.9"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA026815	Uncertain		Approved	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"	2.4	1.0	0.6	13.8	0.6	11.6	3.2	0.6	0.6	1.8	4.0	0.2	0.2	1.4	1.5	2.7	3.0	1.0	0.7	2.1	0.6	0.7	1.0	1.4	3.5	5.3	0.7	0.5	1.4	3.3	0.4	0.7	7.0	0.8	0.9	2.0	0.1	1.8	0.3	3.3	1.8	3.2	0.8	2.1	6.6	1.5	16.9	0.1	23.2	0.9	4.8	4.2	1.3	1.7	1.3	1.9	0.4	0.2	1.5	0.8	0.0	3.9	3.5	6.0	4.5	0.6	1.6	6.2	4.3	2.7	5.0	4.6	8.2	5.3	14.0	2.8	2.1	5.4	4.9	2.5	9.6	9.1	2.6	8.9	2.2	3.2	0.2	12.7	4.4	0.3	0.3	9.1	6.3	4.0	5.8	4.9	5.7	4.5	10.1	7.5	7.2	1.9	10.0	15.5	2.7	1.3	4.3	2.3	4.3	5.2	2.2	2.1	2.6	6.3	3.1	5.7	6.1	6.3	5.9	1.9	2.9	7.2	2.9	5.1	5.4	0.1	0.2	0.2	0.3	0.2	0.1	0.9	0.4	0.2	0.2	1.3	0.6	0.8	0.4	1.5	0.2	1.9	0.4	0.0	0.6	0.6	0.6	0.6	0.6	0.7	0.7	0.5	0.8	0.1
BRIP1	"BACH1, FANCJ, OF"	ENSG00000136492	"BRCA1 interacting protein C-terminal helicase 1"	Q9BX63	17	61681266-61863521	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 30.1"	"Cell line enhanced"	"Detected in many"		"MCF7: 41.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"B-cells: 2.2;granulocytes: 2.1;T-cells: 3.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005474	Approved		Supported	"Nucleoplasm,Nuclear membrane"				"Nucleoplasm, Nuclear membrane"		"HPA005474: AB_2667333"	"unprognostic (1.88e-1)"	"unprognostic (1.55e-2)"	"prognostic favourable (3.45e-5)"	"unprognostic (6.85e-4)"	"unprognostic (3.09e-1)"	"prognostic favourable (3.62e-4)"	"unprognostic (2.60e-3)"	"unprognostic (5.60e-2)"	"unprognostic (5.66e-3)"	"unprognostic (6.71e-2)"	"unprognostic (1.50e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.41e-12)"	"unprognostic (1.19e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.62e-3)"	1.0	0.9	0.7	6.3	3.5	9.1	1.1	0.6	1.4	1.4	2.6	0.2	0.6	2.8	1.5	1.2	3.7	0.8	1.8	0.4	0.5	0.5	0.6	2.3	1.3	4.0	0.5	0.9	2.1	1.3	0.1	0.4	1.7	0.7	1.0	2.8	0.4	1.4	0.0	0.4	2.7	5.5	1.0	0.5	2.3	1.3	10.8	0.4	30.1	0.4	2.0	6.6	1.3	1.7	2.2	0.5	2.1	0.3	0.6	3.7	0.5	12.3	4.2	12.2	6.9	0.4	1.1	2.7	11.4	6.7	12.2	15.8	4.3	3.9	7.3	2.6	2.4	4.5	6.3	2.3	16.4	1.8	7.7	7.5	6.7	5.3	0.1	9.6	4.4	0.2	0.1	9.7	2.6	2.6	5.2	5.0	7.6	41.4	15.2	3.3	2.6	3.6	9.5	23.4	3.5	1.6	5.6	4.9	12.7	4.4	1.5	1.8	4.1	3.7	2.2	18.0	13.1	6.6	13.1	3.1	6.0	7.9	3.7	4.6	4.5	2.1	0.3	1.5	0.5	0.2	0.6	2.2	1.2	0.6	0.4	1.8	1.8	0.9	1.0	0.6	0.2	0.5	3.7	0.5	0.7	3.5	0.6	1.4	0.5	0.5	0.5	0.9	0.7	0.4
BUB1B	"Bub1A, BUBR1, MAD3L, SSK1"	ENSG00000156970	"BUB1 mitotic checkpoint serine/threonine kinase B"	O60566	15	40161023-40221136	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 49.5;testis: 25.6"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"naive B-cell: 2.8;plasmacytoid DC: 2.8"	"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			HPA008419			Supported	Cytosol				Cytosol		"HPA008419: AB_1078308"	"unprognostic (4.40e-2)"	"unprognostic (2.23e-1)"	"unprognostic (4.65e-2)"	"unprognostic (2.44e-3)"	"unprognostic (9.66e-2)"	"unprognostic (3.52e-2)"	"prognostic unfavourable (7.43e-6)"	"prognostic unfavourable (3.56e-4)"	"unprognostic (3.69e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavourable (1.79e-4)"	"unprognostic (1.76e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.75e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.20e-1)"	"unprognostic (3.94e-2)"	1.0	0.9	0.3	18.4	0.6	11.4	1.5	0.4	0.5	1.3	4.0	0.4	0.1	3.3	1.1	0.8	6.5	0.5	1.1	0.6	0.4	0.4	0.8	0.7	1.8	8.7	0.4	0.3	0.6	0.5	0.0	0.4	3.4	0.5	0.6	4.4	0.3	1.6	0.1	0.7	2.3	2.9	1.2	0.6	5.4	1.7	25.6	0.1	49.5	0.5	3.1	10.6	1.1	2.0	2.8	2.8	0.0	0.2	0.7	0.7	0.5	21.6	11.0	35.1	13.9	0.8	2.5	11.3	20.5	11.5	22.0	19.1	16.0	8.3	19.6	11.5	7.4	24.4	33.1	11.1	24.0	16.8	17.8	28.6	28.4	14.9	0.0	25.7	15.7	0.5	0.6	13.4	12.7	15.9	24.6	20.9	21.9	7.3	20.2	15.7	23.7	12.5	21.7	28.8	14.8	6.7	11.0	22.9	14.1	12.7	12.1	4.5	14.1	13.4	9.2	16.9	17.9	16.8	18.2	10.9	18.5	32.0	9.0	29.0	21.9	0.0	0.0	0.0	0.2	0.2	0.3	2.4	0.7	0.6	0.7	2.8	0.1	0.4	0.0	0.7	0.1	2.8	0.0	0.5	0.3	0.6	0.4	0.5	0.4	0.4	0.4	0.3	0.5	0.1
CASP8	"Casp-8, FLICE, MACH, MCH5"	ENSG00000064012	"Caspase 8"	Q14790	2	201233443-201287711	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"blood: 52.5"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001302, CAB002047, HPA005688, HPA006191"	Approved		Supported	Nucleoplasm,Cytosol				Cytosol	Nucleoplasm	"CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: "	"unprognostic (5.21e-3)"	"unprognostic (2.10e-1)"	"unprognostic (1.83e-2)"	"unprognostic (9.69e-3)"	"unprognostic (2.09e-1)"	"unprognostic (5.60e-2)"	"prognostic unfavourable (3.02e-4)"	"unprognostic (2.10e-1)"	"unprognostic (4.79e-2)"	"prognostic favourable (1.25e-4)"	"unprognostic (7.75e-2)"	"unprognostic (5.11e-2)"	"prognostic unfavourable (1.27e-6)"	"unprognostic (7.67e-3)"	"unprognostic (2.43e-1)"	"unprognostic (2.53e-1)"	"unprognostic (4.53e-3)"	14.1	10.6	2.0	31.6	2.6	27.1	10.2	1.4	1.8	7.9	18.5	3.9	7.0	9.6	9.6	12.0	11.7	9.1	12.1	4.4	2.1	2.3	16.4	14.8	17.1	28.3	3.9	1.1	8.2	7.6	1.8	5.9	12.3	3.2	9.8	8.7	4.4	9.6	8.4	2.7	7.4	34.7	5.1	5.0	37.7	7.4	3.8	2.7	43.7	6.7	10.7	43.4	9.6	7.3	13.8	13.7	52.5	17.0	22.2	26.4	12.0	14.3	12.2	3.6	9.9	10.0	14.6	5.5	6.3	6.2	7.5	12.4	16.4	25.0	1.6	13.9	4.9	7.3	7.8	7.5	14.8	9.3	7.1	14.0	9.9	15.6	8.1	10.8	15.2	12.7	18.5	14.2	11.1	7.1	12.5	31.2	6.8	5.9	14.1	11.5	5.8	10.9	10.6	7.4	25.5	14.1	16.0	1.0	0.5	8.2	13.6	8.1	3.6	8.5	8.8	8.1	8.4	4.2	4.9	28.3	12.6	9.7	12.2	14.6	7.6	20.7	13.0	24.9	25.0	17.0	23.1	13.8	20.5	26.4	13.7	7.8	13.3	16.9	52.5	22.2	15.6	6.1	24.0	12.0	2.0	2.6	1.4	1.8	2.1	2.3	3.9	1.1	3.2	2.7
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121997-193253901	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016359, HPA030772"	Supported		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA030772: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"	23.4	20.0	18.1	16.8	22.9	21.0	20.1	25.6	22.6	20.4	20.1	14.5	16.3	12.0	26.8	15.2	20.6	14.9	16.4	21.4	18.4	15.0	18.8	17.1	17.2	16.6	19.7	15.9	23.3	14.5	27.1	24.8	17.3	19.4	26.9	16.2	13.6	17.3	19.0	44.5	15.0	14.5	25.6	23.9	16.0	15.7	16.3	22.1	20.6	27.1	14.1	15.8	26.8	35.0	6.6	6.7	10.2	7.0	9.0	12.5	5.2	13.3	12.0	15.9	10.2	14.9	14.5	12.2	14.4	14.0	17.4	15.3	8.2	15.9	17.4	10.2	17.7	13.1	14.4	13.6	21.3	11.0	6.8	12.6	10.9	8.0	14.0	17.1	12.6	11.8	13.2	16.3	15.6	14.8	19.1	14.1	23.3	12.3	13.9	8.5	15.3	4.5	12.5	9.6	16.6	20.4	9.3	4.8	13.1	18.0	22.2	20.5	19.1	12.4	16.5	17.0	3.9	14.4	14.7	13.2	9.8	14.3	10.2	10.5	29.6	6.6	7.0	10.2	9.3	6.8	12.5	6.6	9.2	9.2	6.7	5.4	8.4	8.7	7.4	9.0	5.7	4.9	9.3	5.2	18.1	22.9	25.6	22.6	18.4	15.0	19.7	15.9	19.4	22.1
CDH1	"CD324, UVO, uvomorulin"	ENSG00000039068	"Cadherin 1"	P12830	16	68737225-68835548	"Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Disease mutation, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 125.5"	"Cell line enhanced"	"Detected in some"		"BEWO: 105.6;CACO-2: 35.5;CAPAN-2: 49.6;HaCaT: 47.9;hTCEpi: 33.8;MCF7: 29.3;RT4: 36.5;T-47d: 31.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	12	"myeloid DC: 2.8;plasmacytoid DC: 8.5"	"Lineage enriched"	"Detected in single"	18	"dendritic cells: 8.5"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions"			22000000	"Plasma membrane, Cell Junctions"	"Golgi apparatus"	"CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: , CAB072856: , CAB072857: , HPA004812: AB_1078369"	"unprognostic (3.95e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.42e-1)"	"unprognostic (2.78e-1)"	"unprognostic (5.04e-3)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.19e-2)"	"unprognostic (3.61e-1)"	"prognostic favourable (2.06e-4)"	"unprognostic (1.21e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.51e-1)"	"unprognostic (5.92e-2)"	1.1	0.7	1.3	14.8	1.5	0.5	15.3	0.8	1.1	14.4	63.8	1.8	42.4	25.5	4.7	18.6	48.5	9.7	48.9	0.8	1.5	1.0	24.2	64.9	24.4	0.5	1.8	0.9	5.6	71.5	62.2	13.2	55.2	2.8	28.9	25.9	11.8	66.6	43.7	0.8	30.5	125.5	1.5	1.1	3.5	21.6	2.1	1.8	11.7	83.0	26.2	32.6	16.8	21.7	0.0	8.5	0.0	0.0	0.3	0.4	0.1	21.3	2.2	0.0	0.0	0.0	0.0	105.6	0.0	0.0	0.0	0.0	35.5	49.6	0.0	0.4	0.0	47.9	0.0	23.8	0.0	4.1	0.6	0.0	0.1	7.6	0.0	0.0	0.2	0.0	33.8	0.0	0.0	0.0	0.0	0.0	0.0	29.3	0.0	0.1	0.8	0.1	0.0	0.0	0.3	8.7	36.5	1.3	0.1	0.2	0.0	9.0	31.5	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.4	2.8	0.0	0.0	0.0	0.0	0.3	0.0	8.5	0.1	0.1	1.3	1.5	0.8	1.1	1.5	1.0	1.8	0.9	2.8	1.8
CDK12	"CRK7, CRKR, CRKRS, KIAA0904"	ENSG00000167258	"Cyclin dependent kinase 12"	Q9NYV4	17	39461511-39564907	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 85.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008038, HPA073305"	Supported		Enhanced	"Nucleoplasm,Nuclear speckles"				"Nucleoplasm, Nuclear speckles"		"HPA008038: AB_1078570, HPA073305: "	"unprognostic (2.02e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.61e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.05e-1)"	"unprognostic (3.19e-1)"	"unprognostic (2.56e-3)"	"unprognostic (2.37e-2)"	"unprognostic (3.86e-2)"	"unprognostic (3.00e-3)"	"unprognostic (6.87e-3)"	"unprognostic (1.86e-1)"	"unprognostic (3.06e-2)"	"unprognostic (9.10e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.22e-2)"	"unprognostic (5.32e-1)"	16.0	13.1	12.4	17.4	9.2	32.4	14.0	23.4	17.8	18.2	17.6	9.6	15.7	11.1	15.7	12.0	16.9	12.2	12.5	11.0	10.1	6.7	10.2	18.5	13.5	15.2	10.9	14.3	17.4	11.3	19.0	12.2	18.4	9.5	12.7	11.7	10.4	15.6	11.1	11.1	17.0	16.5	11.0	10.6	16.3	11.8	18.9	8.3	29.0	15.0	5.4	17.3	16.3	20.5	5.1	4.0	10.4	2.9	6.6	4.0	0.9	8.7	10.8	6.5	6.1	4.8	5.4	6.1	7.9	6.7	10.9	8.1	13.3	5.4	12.4	7.0	8.3	14.2	13.0	10.0	10.5	8.1	11.2	13.4	7.4	10.3	4.7	18.3	9.4	5.8	6.9	13.2	10.5	6.6	22.7	8.2	6.2	4.1	14.9	4.7	6.8	4.9	9.9	14.1	7.0	4.1	10.5	7.0	4.5	10.1	85.6	6.9	11.0	7.9	7.1	9.9	7.9	6.9	10.2	6.7	4.8	17.5	7.0	7.8	6.4	10.4	2.9	4.1	4.0	2.2	3.0	2.9	2.5	2.7	1.8	5.1	2.9	2.7	9.7	6.6	1.8	4.0	2.0	0.9	12.4	9.2	23.4	17.8	10.1	6.7	10.9	14.3	9.5	8.3
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967753-21995301	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 22.6;pituitary gland: 39.3"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 50.0;HEK 293: 56.7;HeLa: 53.1;SK-MEL-30: 53.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"T-reg: 22.6"	"Group enriched"	"Detected in many"	8	"B-cells: 7.2;T-cells: 22.6"					"Low region specificity"	"Detected in many"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli				Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: "	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavourable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favourable (5.19e-4)"	"prognostic unfavourable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavourable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	5.4	8.6	2.9	4.5	3.9	1.8	5.3	1.7	3.1	1.2	2.5	4.4	0.1	1.2	1.2	1.9	6.3	3.0	2.6	0.7	1.7	1.0	0.9	1.2	3.0	3.0	3.6	1.6	1.5	1.5	8.5	39.3	6.7	5.0	1.9	1.1	1.2	2.4	2.9	0.9	1.3	3.7	1.0	3.0	8.9	6.0	13.0	1.9	3.9	1.4	3.0	14.0	2.7	1.5	7.2	0.2	0.8	1.8	0.4	22.6	2.2	2.1	0.0	0.3	14.1	0.1	0.1	6.1	2.3	0.0	19.6	34.9	3.5	50.0	7.2	32.2	1.6	6.0	5.9	36.4	15.8	30.9	56.7	0.0	53.1	2.3	1.5	3.5	3.0	3.8	0.0	19.8	11.0	2.0	0.0	32.9	17.9	0.1	0.3	0.0	0.4	29.2	0.0	13.3	26.4	4.0	0.0	33.0	2.3	38.0	6.3	53.0	7.5	0.1	6.5	0.1	0.4	0.0	0.1	14.7	8.3	29.4	0.0	9.4	0.1	0.8	1.3	0.2	6.2	0.6	9.7	7.2	8.0	11.0	0.2	7.0	0.5	4.7	0.4	0.4	1.8	0.0	22.6	2.2	2.9	3.9	1.7	3.1	1.7	1.0	3.6	1.6	5.0	1.9
CEBPA	"C/EBP-alpha, CEBP"	ENSG00000245848	"CCAAT/enhancer binding protein alpha"	P49715	19	33299934-33302564	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"breast: 52.3;liver: 44.3"	"Cell line enhanced"	"Detected in some"		"BEWO: 42.6;Hep G2: 22.8;NB-4: 23.5;THP-1: 85.0;U-937: 27.2"	"Cancer enhanced"	"Detected in all"		"liver cancer: 70.6"	"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"basophil: 11.0;non-classical monocyte: 11.8"	"Group enriched"	"Detected in many"	13	"dendritic cells: 4.1;granulocytes: 11.0;monocytes: 11.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA052734, HPA065037, HPA067937"	Approved		Approved	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"HPA052734: , HPA065037: , HPA067937: "	"unprognostic (1.80e-1)"	"unprognostic (7.62e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.21e-2)"	"unprognostic (3.38e-1)"	"unprognostic (3.99e-2)"	"unprognostic (1.94e-1)"	"unprognostic (2.43e-3)"	"unprognostic (5.95e-2)"	"unprognostic (3.96e-2)"	"unprognostic (3.09e-1)"	"unprognostic (9.45e-2)"	"unprognostic (8.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (1.98e-1)"	"unprognostic (2.49e-2)"	"unprognostic (2.72e-2)"	40.7	1.5	2.3	7.6	4.6	8.4	52.3	2.1	4.0	3.5	9.0	5.2	1.1	9.0	2.2	2.1	6.1	2.4	6.4	6.6	3.9	2.4	2.0	44.3	39.9	10.3	4.1	3.1	1.3	9.0	4.5	1.7	17.4	2.7	3.8	5.1	1.9	5.6	1.6	15.4	23.7	12.7	2.9	6.6	3.0	3.5	1.2	2.6	2.2	2.5	10.7	3.5	5.4	7.9	0.1	4.1	11.0	11.8	0.0	0.6	1.5	0.5	1.0	0.0	1.5	12.3	0.0	42.6	0.0	0.3	0.0	0.0	5.1	0.0	0.0	0.6	0.0	1.9	1.2	0.1	0.0	7.3	1.5	0.0	0.0	22.8	0.2	7.5	9.1	0.4	5.5	0.0	0.0	0.0	0.4	0.0	0.0	2.6	0.0	23.5	1.0	0.5	0.0	0.0	0.2	0.0	3.7	0.0	0.3	0.1	0.1	0.1	2.9	85.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	27.2	0.0	11.0	6.0	0.0	0.6	9.4	0.6	0.0	0.1	0.4	4.1	0.1	0.2	0.4	2.1	0.0	11.8	0.2	0.0	1.5	2.3	4.6	2.1	4.0	3.9	2.4	4.1	3.1	2.7	2.6
CHD4	"Mi-2b, Mi2-BETA"	ENSG00000111642	"Chromodomain helicase DNA binding protein 4"	Q14839	12	6570082-6614524	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA012008	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"HPA012008: AB_1846633"	"unprognostic (6.11e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.71e-2)"	"unprognostic (6.40e-3)"	"unprognostic (8.99e-2)"	"unprognostic (3.36e-3)"	"prognostic unfavourable (6.03e-6)"	"unprognostic (2.66e-2)"	"unprognostic (1.05e-1)"	"unprognostic (6.85e-2)"	"unprognostic (3.15e-1)"	"unprognostic (3.94e-1)"	"unprognostic (2.06e-1)"	"unprognostic (3.33e-1)"	"unprognostic (1.82e-1)"	"unprognostic (9.84e-2)"	"unprognostic (1.66e-1)"	23.5	34.9	21.9	50.0	33.5	27.2	25.9	29.4	25.1	28.1	29.5	29.3	38.5	18.6	37.2	35.4	29.1	28.0	40.3	52.8	23.5	19.2	29.5	25.0	25.5	30.9	33.6	19.4	34.6	27.4	58.4	25.3	29.5	27.2	21.5	26.0	26.5	24.8	46.2	33.7	31.1	24.4	36.6	30.3	29.4	27.2	29.7	28.9	75.7	38.4	33.7	38.4	34.7	24.3	12.6	16.8	12.8	9.1	13.5	16.7	5.8	20.5	18.7	46.5	17.4	19.1	21.5	27.3	22.8	22.2	25.2	23.2	31.2	16.0	44.2	9.1	25.7	18.4	43.6	25.1	34.0	33.0	22.4	61.7	29.1	19.5	16.6	48.4	29.6	20.7	12.5	24.3	17.1	29.3	48.5	22.1	23.9	25.7	45.9	15.8	44.5	17.7	39.4	28.6	24.1	15.9	24.3	22.0	28.3	29.3	32.6	22.6	14.9	27.6	27.2	25.7	54.8	18.8	26.6	35.8	21.3	56.4	17.0	29.6	18.8	9.0	7.7	9.2	12.2	9.1	12.0	10.5	10.3	11.1	7.9	12.6	13.0	12.3	12.8	13.5	8.1	16.8	16.7	5.8	21.9	33.5	29.4	25.1	23.5	19.2	33.6	19.4	27.2	28.9
CNOT3	"KIAA0691, LENG2, NOT3, NOT3H"	ENSG00000088038	"CCR4-NOT transcription complex subunit 3"	O75175	19	54137717-54155708	"Cancer-related genes, Predicted intracellular proteins"	"RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation"	"Developmental protein, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HEK 293: 71.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006408	Approved		Approved	Cytosol				Cytosol		"HPA006408: AB_1078543"	"unprognostic (1.23e-1)"	"unprognostic (2.54e-1)"	"unprognostic (1.75e-2)"	"unprognostic (1.40e-1)"	"unprognostic (4.86e-2)"	"unprognostic (1.90e-1)"	"prognostic unfavourable (2.22e-4)"	"unprognostic (9.06e-2)"	"unprognostic (1.43e-2)"	"unprognostic (2.65e-2)"	"unprognostic (9.30e-3)"	"unprognostic (4.08e-3)"	"prognostic unfavourable (2.77e-4)"	"unprognostic (2.18e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.66e-2)"	18.1	25.2	25.5	23.6	26.4	21.4	20.2	46.8	27.9	22.1	20.7	24.5	27.7	21.3	25.0	26.5	22.1	23.6	19.7	16.2	21.9	15.6	21.3	20.2	17.9	23.9	25.5	20.8	28.0	22.7	27.6	30.2	24.2	20.3	23.3	17.5	20.7	22.4	31.4	20.2	25.2	21.4	22.0	16.7	26.3	21.9	34.4	26.9	33.6	26.3	14.3	23.3	23.8	29.9	3.2	6.7	8.4	3.1	1.6	3.6	2.9	13.6	22.0	22.8	13.1	8.5	8.6	16.0	12.8	22.2	17.2	15.4	14.1	11.8	16.8	8.2	14.8	14.4	25.3	12.5	17.8	17.4	71.4	26.1	14.3	12.5	14.8	14.9	18.3	10.9	12.0	15.3	25.9	13.6	19.2	15.8	12.6	16.9	18.4	8.8	13.9	17.7	18.4	17.5	10.9	11.5	27.7	14.7	12.5	24.7	17.8	8.1	10.2	16.0	12.1	14.6	16.9	7.7	17.3	14.8	16.2	23.2	12.7	11.4	15.4	1.4	3.1	5.2	3.6	2.2	2.5	2.9	2.4	3.2	2.8	3.2	2.7	2.6	8.4	1.6	2.6	6.7	2.5	2.9	25.5	26.4	46.8	27.9	21.9	15.6	25.5	20.8	20.3	26.9
COL2A1	"AOM, SEDC, STL1"	ENSG00000139219	"Collagen type II alpha 1 chain"	P02458	12	47972965-48004554	"Cancer-related genes, Disease related genes, Predicted secreted proteins"			"Cancer-related genes, Cataract, Deafness, Disease mutation, Dwarfism, Stickler syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"epididymis: 22.7;pituitary gland: 11.0;retina: 8.1;stomach 1: 11.3"	"Cell line enhanced"	"Detected in some"		"AF22: 54.0;HAP1: 33.8;HEK 293: 12.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"CAB002214, HPA055753"	Supported		Approved	Nucleoplasm	"Secreted to extracellular matrix"			Nucleoplasm		"CAB002214: AB_563666, HPA055753: "	"unprognostic (7.25e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.58e-1)"	"unprognostic (3.44e-1)"	"unprognostic (2.88e-2)"	"unprognostic (3.08e-2)"	"unprognostic (8.63e-2)"	"unprognostic (2.77e-1)"	"unprognostic (1.22e-1)"	"unprognostic (3.12e-2)"	"unprognostic (1.31e-4)"	"unprognostic (2.64e-1)"	"unprognostic (3.44e-3)"	"unprognostic (1.89e-1)"	"unprognostic (2.93e-1)"	"unprognostic (2.07e-1)"	"unprognostic (1.02e-1)"	0.0	0.0	0.1	2.2	0.3	0.0	0.7	0.9	0.9	0.0	0.2	0.3	0.0	0.0	0.3	22.7	0.0	0.0	0.0	0.0	0.5	1.3	0.0	0.0	1.4	0.0	0.0	0.7	1.3	0.0	0.0	11.0	0.4	1.9	2.6	0.4	8.1	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	11.3	2.8	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	54.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	0.2	0.0	0.0	33.8	0.0	0.0	0.0	12.5	0.0	0.0	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.7	0.0	0.0	1.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.9	0.9	0.5	1.3	0.0	0.7	1.9	0.0
CREBBP	"CBP, KAT3A, RSTS, RTS"	ENSG00000005339	"CREB binding protein"	Q92793	16	3725054-3880726	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Transcription, Transcription regulation"	"Activator, Acyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004212, HPA055861"	Supported		Enhanced	"Nucleoplasm,Nuclear bodies"				Nucleoplasm	"Nuclear bodies"	"CAB004212: AB_626817, HPA055861: "	"unprognostic (1.17e-1)"	"unprognostic (8.51e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.63e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.09e-2)"	"unprognostic (9.59e-3)"	"unprognostic (6.98e-2)"	"unprognostic (8.96e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (2.84e-1)"	"prognostic favourable (6.24e-5)"	"unprognostic (1.47e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.97e-2)"	"unprognostic (8.23e-2)"	18.5	10.9	17.2	22.8	17.5	37.0	17.4	42.6	18.8	20.1	17.2	16.8	17.1	9.9	25.1	15.2	14.1	18.9	21.3	14.5	17.1	8.7	11.1	12.3	16.9	14.4	20.5	12.0	31.6	23.4	24.3	13.0	13.3	15.8	18.4	11.6	14.6	14.9	16.7	28.2	20.4	16.4	17.0	13.6	17.4	14.7	29.1	20.2	29.6	19.5	13.8	16.1	19.0	29.9	4.7	2.3	10.6	3.8	2.0	2.7	1.1	5.5	14.3	18.6	8.2	11.4	11.3	9.6	8.0	13.5	13.9	13.5	12.9	10.5	15.4	9.6	15.3	10.8	21.4	6.6	15.8	26.0	8.6	12.1	13.2	8.2	12.6	12.1	17.4	10.0	6.7	15.4	18.6	10.4	13.7	21.1	7.5	19.1	8.0	5.8	15.2	5.9	37.8	14.7	11.8	5.4	7.5	15.5	10.2	13.7	13.5	8.1	12.0	11.9	16.1	17.0	16.9	8.7	7.3	9.9	10.6	29.9	3.4	7.3	11.9	2.9	1.7	1.3	2.7	2.2	1.4	4.7	1.3	2.0	1.0	3.3	1.4	1.7	10.6	2.0	3.8	2.3	1.3	1.1	17.2	17.5	42.6	18.8	17.1	8.7	20.5	12.0	15.8	20.2
CSF3R	"CD114, GCSFR"	ENSG00000119535	"Colony stimulating factor 3 receptor"	Q99062	1	36466043-36483278	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	Receptor	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"blood: 167.3;bone marrow: 88.9;lymphoid tissue: 71.4;placenta: 152.7"	"Group enriched"	"Detected in some"	18	"BEWO: 34.1;NB-4: 9.2;THP-1: 22.4;U-937: 21.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Cell type enriched"	"Detected in some"	8	"neutrophil: 167.3"	"Lineage enriched"	"Detected in many"	8	"granulocytes: 167.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB017116, HPA048086"	Enhanced				"Intracellular and membrane"					"CAB017116: , HPA048086: "	"unprognostic (5.57e-3)"	"unprognostic (8.05e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.87e-2)"	"unprognostic (2.88e-1)"	"unprognostic (2.92e-2)"	"unprognostic (2.86e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.83e-1)"	"unprognostic (5.65e-2)"	"unprognostic (2.47e-1)"	"unprognostic (3.44e-1)"	"prognostic unfavourable (5.72e-4)"	"unprognostic (6.33e-2)"	"prognostic unfavourable (3.79e-4)"	"unprognostic (2.03e-1)"	"unprognostic (2.31e-2)"	8.5	1.5	2.9	39.5	3.2	88.9	2.4	0.7	2.9	1.1	1.1	4.2	0.4	0.6	0.7	1.1	1.2	6.9	4.3	5.6	2.6	2.0	1.7	4.5	26.9	27.5	7.2	1.1	1.1	1.3	0.3	1.1	152.7	3.8	1.3	0.5	2.1	1.6	0.5	0.6	0.3	1.6	3.1	7.1	71.4	2.2	1.4	3.3	1.1	1.0	0.4	0.9	4.6	3.9	0.0	8.2	167.3	22.1	0.2	0.0	10.3	0.0	0.0	0.0	0.0	0.0	0.0	34.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.8	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	9.2	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	22.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	21.6	0.0	0.0	22.1	0.6	0.0	4.8	0.0	0.0	0.0	0.0	8.2	0.0	0.0	0.0	167.3	0.2	1.8	0.2	0.0	10.3	2.9	3.2	0.7	2.9	2.6	2.0	7.2	1.1	3.8	3.3
CTCF		ENSG00000102974	"CCCTC-binding factor"	P49711	16	67562407-67639185	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Chromosome partition, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004122, CAB062550, CAB068181, CAB068182"	Supported		Supported	Nucleoplasm				Nucleoplasm		"CAB062550: , CAB068181: , CAB068182: , HPA004122: "	"unprognostic (2.70e-1)"	"unprognostic (4.21e-2)"	"unprognostic (3.41e-2)"	"unprognostic (4.70e-2)"	"unprognostic (4.41e-2)"	"unprognostic (2.70e-1)"	"prognostic unfavourable (4.21e-4)"	"unprognostic (1.71e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.99e-2)"	"prognostic favourable (4.06e-4)"	"unprognostic (3.47e-1)"	"unprognostic (5.99e-2)"	"unprognostic (4.58e-2)"	"unprognostic (1.11e-2)"	19.1	17.5	22.3	35.0	24.3	32.2	20.2	31.6	26.6	23.0	19.4	20.5	21.0	16.5	24.2	15.4	23.1	21.7	20.3	17.6	21.8	16.7	19.5	19.5	17.2	27.9	22.3	21.0	24.6	21.2	42.4	21.8	23.5	17.9	19.4	23.2	14.3	19.9	24.9	29.4	25.2	21.4	22.0	20.2	26.1	18.5	14.8	22.9	68.8	20.7	16.2	35.5	22.6	26.7	10.1	7.9	9.6	6.2	4.9	7.2	1.9	10.9	16.9	22.5	8.9	10.3	8.8	18.3	10.5	11.1	15.5	14.9	13.8	11.4	34.4	8.5	9.1	14.2	21.7	11.8	17.6	12.2	14.3	20.8	9.6	15.8	7.0	23.6	20.0	7.1	14.3	11.6	13.0	11.8	18.2	14.4	12.8	21.5	49.5	9.0	19.5	11.3	36.2	18.5	18.9	9.5	15.9	19.3	13.4	19.0	11.1	9.3	13.7	14.7	11.2	13.4	13.9	10.2	11.5	12.6	15.8	50.1	7.7	14.2	14.3	9.4	3.4	4.9	6.7	3.4	6.3	7.9	7.2	5.4	3.1	10.1	5.9	6.7	9.6	4.9	6.2	7.9	5.4	1.9	22.3	24.3	31.6	26.6	21.8	16.7	22.3	21.0	17.9	22.9
CUX1	"CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6"	ENSG00000257923	"Cut like homeobox 1"	"Q13948, P39880"	7	101815904-102283958	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation, Transport"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"non-classical monocyte: 21.0"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003277, HPA003317"	Approved		Supported	"Nucleoplasm,Golgi apparatus"				"Nucleoplasm, Golgi apparatus"		"HPA003277: AB_10601804, HPA003317: "	"unprognostic (5.86e-2)"	"unprognostic (5.39e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.73e-1)"	"prognostic unfavourable (7.51e-4)"	"unprognostic (5.85e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.89e-3)"	"unprognostic (2.20e-1)"	"unprognostic (2.50e-1)"	"prognostic favourable (5.72e-7)"	"unprognostic (1.12e-1)"	"unprognostic (8.85e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.97e-1)"	19.3	12.7	22.9	19.2	24.4	19.5	12.3	48.6	29.9	31.6	26.4	23.1	17.3	22.2	52.1	17.4	23.9	24.5	23.2	53.8	18.8	18.3	27.4	16.0	22.0	11.8	20.4	11.7	33.0	41.4	34.4	30.2	24.4	16.9	22.8	17.2	26.8	26.3	16.9	31.0	15.9	25.3	27.5	31.6	15.0	23.4	8.3	17.1	44.0	33.5	23.2	24.1	31.8	21.9	2.0	12.1	4.7	21.0	3.0	2.2	4.5	14.3	15.4	10.9	13.4	8.8	18.3	6.8	14.4	15.3	6.1	4.0	9.1	9.2	18.5	23.2	14.2	11.8	6.9	11.6	3.7	8.9	7.7	6.5	11.4	7.6	23.5	8.4	3.6	12.7	23.7	4.7	10.7	7.9	15.1	15.8	5.7	29.5	27.3	10.3	4.4	16.1	18.1	9.0	22.0	10.1	16.4	10.0	29.8	12.6	31.6	12.3	6.2	10.1	11.7	25.9	17.5	19.5	8.2	10.3	4.9	40.1	23.9	7.8	18.0	2.1	8.6	1.5	2.1	8.8	2.2	2.0	1.6	2.2	7.0	1.7	1.6	2.2	4.7	3.0	21.0	12.1	1.5	4.5	22.9	24.4	48.6	29.9	18.8	18.3	20.4	11.7	16.9	17.1
CXCR4	"CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R"	ENSG00000121966	"C-X-C motif chemokine receptor 4"	P61073	2	136114349-136118165	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 149.9;lymphoid tissue: 186.3"	"Cell line enhanced"	"Detected in many"		"Daudi: 75.5;Karpas-707: 40.5;MOLT-4: 68.5;REH: 36.3;U-266/70: 87.9;U-698: 88.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"														"unprognostic (1.19e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.12e-2)"	"unprognostic (4.99e-2)"	"unprognostic (9.25e-2)"	"unprognostic (6.06e-2)"	"prognostic favourable (2.05e-4)"	"unprognostic (1.23e-1)"	"unprognostic (2.66e-1)"	"prognostic unfavourable (1.41e-7)"	"prognostic unfavourable (5.67e-4)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	"unprognostic (9.33e-2)"	15.4	26.5	3.0	39.1	3.4	149.9	9.7	0.8	2.1	7.7	8.7	6.8	1.5	1.6	8.3	3.8	16.4	9.1	12.0	5.4	4.1	4.7	8.2	7.1	29.3	94.5	6.5	1.3	6.3	3.1	0.7	8.1	7.8	6.1	6.8	7.0	10.0	10.6	2.2	3.2	2.3	57.8	3.8	22.9	82.4	8.0	7.2	3.4	186.3	9.2	4.6	97.5	50.0	6.6	47.3	16.8	37.8	7.2	4.0	32.0	11.9	0.1	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	75.5	0.2	0.0	0.0	0.2	0.0	0.0	3.8	0.9	4.5	12.0	0.0	0.0	10.4	8.2	0.0	0.0	0.0	0.0	7.2	0.1	40.5	0.0	0.2	68.5	9.3	1.2	0.3	36.3	8.4	13.2	0.6	0.0	4.2	3.5	0.0	0.2	0.0	0.0	20.5	1.0	0.0	0.2	0.0	0.0	87.9	14.8	88.4	0.0	17.2	0.0	17.9	7.2	29.6	22.9	3.8	18.7	30.1	21.1	21.7	6.6	47.3	32.0	30.1	37.8	4.0	2.1	16.8	18.9	11.9	3.0	3.4	0.8	2.1	4.1	4.7	6.5	1.3	6.1	3.4
CYLD	"CYLD1, KIAA0849, USPL2"	ENSG00000083799	"CYLD lysine 63 deubiquitinase"	Q9NQC7	16	50742050-50801935	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 46.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011713, HPA050095"	Approved		Supported	"Nucleoplasm,Centriolar satellite"				"Centriolar satellite"	Nucleoplasm	"CAB011713: AB_731794, HPA050095: "	"unprognostic (9.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (5.01e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.84e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.87e-2)"	"unprognostic (3.24e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.18e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (8.42e-2)"	9.3	16.2	13.9	22.9	26.4	51.1	9.1	14.2	20.9	9.2	10.3	18.8	12.8	10.2	16.1	8.1	15.3	8.5	13.3	12.7	15.7	17.0	9.4	13.2	15.6	30.7	16.3	14.3	11.5	12.2	20.3	27.8	9.8	20.0	11.0	12.7	13.3	12.6	10.9	31.7	12.4	14.2	12.5	16.3	23.4	12.4	22.6	13.7	16.9	16.2	8.0	29.3	14.1	12.6	9.2	10.2	31.4	9.8	13.6	19.1	10.2	9.1	2.9	3.3	3.7	5.3	7.7	3.0	13.6	19.9	14.2	8.4	2.4	4.3	10.6	4.9	13.2	3.6	3.9	8.2	21.1	46.4	6.0	5.3	5.1	1.9	10.6	5.2	24.9	8.4	6.7	17.1	17.9	5.7	2.2	9.2	19.8	1.3	5.1	7.6	3.5	4.8	4.6	6.8	10.1	4.6	3.2	4.3	3.3	11.5	3.9	3.3	3.9	6.6	6.4	24.3	5.5	8.5	5.5	24.3	23.1	11.8	17.8	5.9	5.1	31.4	8.6	20.8	10.7	9.8	12.9	9.2	15.8	14.4	10.2	6.2	14.7	11.4	19.4	13.6	9.5	6.2	19.1	10.2	13.9	26.4	14.2	20.9	15.7	17.0	16.3	14.3	20.0	13.7
DAXX	DAP6	ENSG00000204209	"Death domain associated protein"	Q9UER7	6	33318558-33323016	"Cancer-related genes, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction, Transcription, Transcription regulation"	"Chaperone, Chromatin regulator, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002224, HPA008736, HPA008797, CAB025546, HPA065779"	Enhanced		Enhanced	"Nucleoplasm,Nuclear bodies"				"Nucleoplasm, Nuclear bodies"		"CAB002224: AB_563688, CAB025546: , HPA008736: AB_1078625, HPA008797: , HPA065779: "	"prognostic favourable (6.05e-4)"	"unprognostic (2.90e-1)"	"unprognostic (9.66e-2)"	"unprognostic (4.04e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.46e-3)"	"unprognostic (3.48e-1)"	"unprognostic (1.92e-1)"	"unprognostic (8.58e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.01e-2)"	"prognostic unfavourable (6.32e-7)"	"unprognostic (2.43e-1)"	"unprognostic (5.37e-1)"	"unprognostic (1.26e-1)"	"unprognostic (1.04e-1)"	10.4	14.3	10.7	13.5	11.9	8.8	10.8	11.3	14.8	11.8	12.2	9.4	7.3	11.2	13.2	43.7	13.5	12.6	12.1	9.1	9.7	7.3	9.2	12.0	10.3	18.3	10.2	8.5	13.8	18.6	24.4	10.4	11.6	11.6	13.0	14.1	7.3	10.7	15.2	14.8	11.6	12.7	15.5	8.1	20.4	10.5	20.2	11.5	25.0	16.1	6.8	30.9	11.5	10.9	17.0	5.9	12.6	11.2	15.3	18.2	21.8	2.2	0.0	7.1	2.9	1.2	2.3	4.7	7.0	23.1	18.0	13.3	0.8	2.4	7.0	2.5	5.4	1.3	0.1	5.7	16.7	8.3	15.7	9.1	12.5	11.2	3.9	9.6	2.6	6.1	8.5	2.0	5.4	0.5	5.0	4.5	5.6	5.3	3.8	21.5	0.4	3.3	5.9	0.1	7.8	1.4	0.7	8.6	2.2	0.0	0.4	3.7	2.2	0.2	5.9	4.5	5.6	0.2	0.1	7.8	16.3	15.1	3.3	4.4	4.7	7.8	7.5	12.6	16.3	8.0	18.2	16.6	15.4	15.8	5.9	17.0	13.9	14.1	7.4	15.3	11.2	5.9	17.1	21.8	10.7	11.9	11.3	14.8	9.7	7.3	10.2	8.5	11.6	11.5
DDB2	"DDBB, FLJ34321, UV-DDB2, XPE"	ENSG00000134574	"Damage specific DNA binding protein 2"	Q92466	11	47214465-47239240	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB025912, HPA058406"	Enhanced		Supported	"Nucleoplasm,Cell Junctions"				"Nucleoplasm, Cell Junctions"		"CAB025912: , HPA058406: "	"prognostic favourable (7.29e-4)"	"prognostic favourable (1.58e-4)"	"unprognostic (1.49e-1)"	"prognostic favourable (1.20e-4)"	"unprognostic (4.29e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.58e-3)"	"unprognostic (3.53e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.21e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.82e-3)"	"unprognostic (1.07e-1)"	12.2	22.2	5.3	13.3	8.6	8.1	11.3	11.0	8.2	16.8	13.5	7.3	13.4	6.0	18.2	14.1	25.4	14.3	13.0	6.1	4.7	2.9	6.6	20.8	11.3	16.1	15.0	5.0	9.8	15.6	6.1	8.6	5.5	6.3	20.9	12.3	8.1	17.6	14.8	6.3	36.9	11.0	19.0	17.6	15.1	9.1	7.6	7.6	23.3	6.6	16.7	26.0	17.3	15.2	11.4	6.1	11.5	11.0	7.4	27.0	9.0	8.2	22.3	9.3	7.0	6.0	12.2	11.0	9.1	21.3	11.6	13.7	3.6	4.8	19.9	1.9	8.3	14.6	5.3	18.5	5.8	4.9	10.0	4.7	21.3	16.5	5.9	5.4	12.4	16.3	21.0	5.8	13.0	34.0	1.2	9.7	19.0	15.6	20.7	2.6	3.0	8.1	10.4	2.3	10.7	4.9	8.2	4.9	6.1	11.1	3.2	2.9	20.4	1.8	14.6	35.7	16.3	7.8	4.2	10.2	7.7	4.4	13.4	6.9	12.8	5.9	8.1	11.5	12.1	11.0	11.7	11.4	12.7	11.7	6.1	7.4	9.4	10.1	2.2	7.4	9.2	0.1	27.0	9.0	5.3	8.6	11.0	8.2	4.7	2.9	15.0	5.0	6.3	7.6
DDR2	"NTRKR3, TKT, TYRO10"	ENSG00000162733	"Discoidin domain receptor tyrosine kinase 2"	Q16832	1	162631373-162787400	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"	Osteogenesis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"ASC diff: 60.6;ASC TERT1: 59.9;BJ hTERT+: 44.3;fHDF/TERT166: 31.7;HSkMC: 42.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"gdT-cell: 1.1;MAIT T-cell: 1.3"	"Lineage enriched"	"Detected in single"	5	"T-cells: 1.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA070112			Supported	"Plasma membrane,Actin filaments"			850000	"Plasma membrane, Actin filaments"		"HPA070112: "	"unprognostic (4.12e-2)"	"unprognostic (2.73e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.52e-2)"	"unprognostic (1.17e-1)"	"unprognostic (8.16e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.19e-1)"	"unprognostic (6.62e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.15e-1)"	"prognostic unfavourable (1.73e-7)"	"unprognostic (1.56e-3)"	"unprognostic (8.26e-3)"	"unprognostic (7.57e-2)"	"unprognostic (4.10e-3)"	42.1	43.5	4.7	10.9	6.9	0.2	15.6	7.9	7.1	30.3	30.4	9.0	18.6	3.3	24.2	17.7	25.0	13.4	16.6	15.4	7.9	4.7	4.0	3.3	8.9	5.1	12.9	3.4	26.4	2.2	2.1	4.0	6.6	12.7	21.8	9.1	30.7	6.4	19.3	5.2	6.1	10.1	34.3	19.7	3.4	14.1	8.3	7.5	0.0	8.6	12.8	4.1	29.0	18.3	0.1	0.2	0.0	0.0	0.2	1.3	0.0	0.1	0.0	0.0	16.0	60.6	59.9	0.2	23.6	44.3	10.3	14.9	0.0	0.0	0.0	0.0	31.7	0.0	0.0	0.1	14.1	12.7	0.1	0.0	0.0	0.0	26.3	0.0	0.0	42.5	0.1	18.2	0.4	11.8	0.1	5.0	9.4	0.0	0.0	0.0	0.1	0.1	0.0	6.7	0.1	0.0	0.0	0.0	9.7	0.0	0.0	0.8	0.0	0.0	0.6	16.5	3.6	8.3	3.2	0.7	1.3	0.0	14.9	0.0	16.7	0.0	0.0	0.0	1.1	0.0	1.3	0.0	0.8	0.1	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	4.7	6.9	7.9	7.1	7.9	4.7	12.9	3.4	12.7	7.5
DDX3X	"DBX, DDX14, DDX3, HLP2"	ENSG00000215301	"DEAD-box helicase 3, X-linked"	O00571	X	41333284-41364472	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation"	"DNA-binding, Helicase, Hydrolase, RNA-binding"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001648, HPA005631, HPA059585"	Supported	Supported	Approved	Nucleoplasm,Cytosol			110000	Cytosol	Nucleoplasm	"HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: "	"unprognostic (2.42e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.01e-3)"	"unprognostic (1.66e-1)"	"unprognostic (8.12e-2)"	"unprognostic (6.43e-2)"	"unprognostic (1.17e-3)"	"unprognostic (1.88e-1)"	"unprognostic (9.80e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.25e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.95e-1)"	"unprognostic (4.77e-1)"	"unprognostic (9.44e-2)"	"unprognostic (2.93e-2)"	80.9	49.3	26.1	40.0	34.5	49.3	46.5	31.1	36.2	52.4	43.3	35.1	21.3	29.5	56.4	25.9	53.5	56.3	42.6	47.6	30.8	24.5	55.6	77.9	45.3	40.4	41.4	29.0	60.1	30.9	68.7	60.2	79.9	37.9	30.0	29.2	30.8	37.4	26.5	63.4	42.2	54.0	57.2	53.9	46.1	43.0	27.0	39.0	49.2	45.6	44.0	42.6	55.8	50.2	13.1	20.5	32.0	21.6	17.3	21.5	17.9	45.4	50.5	47.2	25.9	55.6	47.2	28.8	33.1	46.6	34.0	27.4	51.9	30.6	0.5	23.7	37.1	30.7	57.7	46.6	56.7	26.9	45.0	28.9	50.3	31.2	28.9	54.1	52.0	34.1	33.1	57.3	55.4	53.3	53.0	28.6	31.6	34.4	34.1	16.9	45.4	20.4	40.0	50.3	37.0	32.0	61.2	32.3	48.9	75.0	38.5	39.7	34.6	36.8	48.1	35.1	37.6	37.5	39.3	33.4	39.6	44.9	35.4	32.8	33.2	22.5	20.2	17.5	14.8	21.1	21.5	13.1	14.5	16.3	20.5	9.0	16.3	15.1	32.0	17.3	21.6	6.9	14.3	17.9	26.1	34.5	31.1	36.2	30.8	24.5	41.4	29.0	37.9	39.0
DICER1	"Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1"	ENSG00000100697	"Dicer 1, ribonuclease III"	Q9UPY3	14	95086228-95158010	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"RNA-mediated gene silencing"	"Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000694, CAB068185"	Approved		Supported	Cytosol				Cytosol		"CAB068185: , HPA000694: AB_1078661"	"unprognostic (2.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.72e-1)"	"unprognostic (6.75e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.52e-3)"	"unprognostic (5.73e-2)"	"unprognostic (9.22e-2)"	"unprognostic (4.22e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.04e-3)"	"unprognostic (3.74e-2)"	23.2	12.5	18.4	22.4	33.3	20.5	23.2	28.5	29.9	19.0	18.1	31.4	22.4	13.0	20.8	20.6	23.4	18.5	16.2	15.3	22.0	14.1	19.5	23.6	22.4	20.3	29.7	19.6	23.8	19.8	26.9	30.9	29.9	23.2	20.3	19.7	14.5	19.5	18.9	28.0	20.7	17.3	19.0	26.8	20.7	17.1	20.6	32.0	17.0	23.8	14.7	20.3	20.7	24.1	2.5	1.8	10.7	7.2	1.2	3.3	1.0	12.8	13.4	25.1	9.3	6.5	9.8	19.9	10.6	6.4	6.8	8.2	17.0	9.9	14.5	11.5	9.8	15.2	19.9	10.0	14.2	22.5	8.9	21.9	7.4	12.2	6.6	13.4	13.5	9.1	8.3	9.1	13.9	10.1	9.2	12.9	11.4	18.0	15.0	8.9	7.1	6.6	12.0	20.5	8.0	9.0	20.5	20.8	11.8	10.7	11.0	12.0	12.4	9.9	10.0	5.2	10.3	10.1	11.9	14.8	21.1	20.6	5.4	10.9	9.3	3.1	3.0	1.2	1.6	3.1	3.3	1.9	1.5	1.2	1.8	2.5	1.5	1.3	10.7	1.2	7.2	1.6	1.6	1.0	18.4	33.3	28.5	29.9	22.0	14.1	29.7	19.6	23.2	32.0
DNM2	"CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII"	ENSG00000079805	"Dynamin 2"	P50570	19	10718079-10833488	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Endocytosis, Phagocytosis"	"Hydrolase, Motor protein"	"Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054246	Supported		Approved	"Golgi apparatus,Cytosol"			500000	"Golgi apparatus, Cytosol"		"HPA054246: "	"unprognostic (2.30e-1)"	"unprognostic (5.23e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.76e-1)"	"prognostic favourable (8.91e-4)"	"prognostic unfavourable (3.63e-4)"	"unprognostic (1.03e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.89e-1)"	"unprognostic (4.75e-2)"	"unprognostic (5.35e-2)"	"unprognostic (5.47e-2)"	"unprognostic (5.40e-3)"	"unprognostic (2.68e-1)"	"unprognostic (1.61e-1)"	"unprognostic (1.99e-3)"	23.8	32.6	18.5	29.3	31.2	53.4	20.4	25.7	29.7	20.1	51.4	57.5	46.0	32.1	20.4	16.8	29.9	19.7	27.0	35.0	20.8	18.0	38.5	25.1	39.2	28.2	48.3	18.0	17.9	32.2	19.5	20.0	32.3	32.2	24.0	42.5	24.5	24.7	37.7	46.6	40.6	50.8	18.6	43.1	37.6	48.2	23.3	36.4	39.1	23.5	21.1	41.5	35.7	31.5	3.4	11.1	8.6	9.8	10.1	5.8	4.6	34.9	28.9	21.2	16.9	21.9	21.5	27.2	23.4	22.2	34.7	29.5	28.8	23.1	25.4	42.2	25.2	30.7	28.9	25.4	29.1	31.1	23.0	48.7	25.8	32.2	27.0	26.7	46.3	22.0	19.6	26.5	25.0	33.7	39.1	43.7	21.3	42.3	37.2	25.5	24.1	35.0	37.8	23.0	28.6	22.8	52.7	30.6	20.0	26.7	22.9	16.7	18.4	31.8	30.5	38.1	12.9	53.5	30.9	36.2	36.9	23.4	28.5	40.9	18.8	3.0	4.5	8.6	5.6	8.2	5.1	3.4	4.2	5.8	5.3	3.1	2.4	4.1	8.5	10.1	9.8	11.1	4.8	4.6	18.5	31.2	25.7	29.7	20.8	18.0	48.3	18.0	32.2	36.4
DNMT3A		ENSG00000119772	"DNA methyltransferase 3 alpha"	Q9Y6K1	2	25227855-25342590	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"		"Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 25.5;REH: 25.1;SH-SY5Y: 31.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009469, HPA026588"	Approved		Supported	Nucleoplasm				Nucleoplasm		"CAB009469: AB_2093990, HPA026588: AB_1847812"	"unprognostic (2.38e-1)"	"unprognostic (2.94e-1)"	"unprognostic (5.65e-2)"	"prognostic unfavourable (1.55e-4)"	"unprognostic (8.38e-2)"	"unprognostic (7.27e-2)"	"prognostic unfavourable (1.58e-4)"	"unprognostic (2.24e-1)"	"unprognostic (7.25e-2)"	"unprognostic (2.72e-1)"	"prognostic favourable (1.18e-4)"	"unprognostic (2.35e-2)"	"prognostic unfavourable (2.49e-4)"	"unprognostic (1.43e-1)"	"unprognostic (1.87e-1)"	"unprognostic (1.14e-1)"	"unprognostic (2.70e-2)"	7.8	12.4	13.7	12.7	15.5	10.8	8.6	21.6	20.1	9.0	12.7	14.5	7.6	9.1	13.0	12.2	8.0	9.6	8.9	8.2	12.3	6.7	9.4	6.9	9.5	13.6	15.3	10.1	18.3	12.1	6.3	12.6	20.8	10.7	9.3	9.2	12.0	8.5	9.2	29.1	6.6	11.4	11.3	7.9	17.5	11.6	6.6	15.2	20.8	9.1	10.5	11.8	9.8	8.4	3.0	4.1	4.9	4.1	8.7	8.3	2.3	1.0	3.5	14.7	3.6	1.6	1.2	19.4	1.0	0.9	2.0	1.6	8.7	5.7	0.0	2.2	1.9	0.9	1.6	2.2	1.2	3.6	2.5	6.3	5.3	10.4	3.8	1.3	4.1	3.6	1.1	2.6	0.9	8.2	7.3	1.3	1.5	8.4	13.8	14.9	25.5	1.9	25.1	16.2	2.1	1.2	1.5	8.8	31.0	1.2	8.4	2.6	0.9	6.7	2.8	2.5	3.2	0.6	1.3	3.1	2.2	8.5	0.9	3.8	2.6	4.7	1.8	3.1	5.2	3.0	7.0	2.3	3.4	4.9	2.0	3.0	8.3	6.6	4.9	8.7	4.1	4.1	2.8	2.3	13.7	15.5	21.6	20.1	12.3	6.7	15.3	10.1	10.7	15.2
DROSHA	"Etohi2, HSA242976, RN3, RNASE3L, RNASEN"	ENSG00000113360	"Drosha ribonuclease III"	Q9NRR4	5	31400497-31532196	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Ribosome biogenesis, RNA-mediated gene silencing"	"Endonuclease, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (8.37e-3)"	"unprognostic (1.81e-1)"	"unprognostic (9.56e-2)"	"prognostic unfavourable (6.79e-4)"	"unprognostic (5.40e-2)"	"unprognostic (6.03e-2)"	"prognostic unfavourable (1.39e-4)"	"unprognostic (3.11e-1)"	"unprognostic (4.08e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.86e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.39e-1)"	"unprognostic (6.94e-2)"	"unprognostic (2.32e-2)"	15.7	16.8	18.4	17.7	32.1	12.2	16.1	33.7	33.7	17.4	16.3	19.1	12.2	15.9	22.3	25.8	16.0	18.2	14.1	15.2	16.6	15.1	15.3	11.7	13.9	17.8	13.6	16.4	26.7	17.8	23.9	38.9	17.0	18.9	17.2	19.2	23.7	17.5	19.2	23.6	16.0	17.5	16.9	19.4	16.8	16.0	12.8	16.4	25.6	21.9	13.4	19.8	18.2	16.2	4.7	6.4	3.3	4.8	4.8	6.4	3.1	12.1	15.4	17.0	23.2	9.1	11.1	24.6	16.1	7.9	15.1	11.3	16.2	15.9	13.7	18.6	11.8	10.7	20.9	12.2	16.8	12.8	14.8	16.8	50.5	11.7	8.2	18.8	50.3	8.8	8.6	16.8	8.1	12.8	21.4	6.5	13.2	12.1	18.1	14.1	16.1	12.3	16.5	32.6	9.9	8.5	13.9	8.9	11.8	41.0	16.8	9.9	15.5	10.8	11.1	14.5	16.9	13.1	15.3	11.8	19.4	15.1	10.1	21.2	13.9	1.8	2.4	3.3	5.2	2.6	5.5	4.2	5.4	6.0	5.2	4.7	6.4	4.4	0.8	4.8	4.8	6.4	5.1	3.1	18.4	32.1	33.7	33.7	16.6	15.1	13.6	16.4	18.9	16.4
EP300	"KAT3B, p300"	ENSG00000100393	"E1A binding protein p300"	Q09472	22	41091786-41180079	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Acyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000146, HPA003128, HPA004112"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746"	"unprognostic (7.67e-2)"	"unprognostic (5.56e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.52e-1)"	"unprognostic (6.10e-3)"	"unprognostic (1.66e-1)"	"unprognostic (2.21e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.54e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.54e-2)"	"prognostic favourable (7.45e-5)"	"unprognostic (7.97e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.66e-2)"	16.8	14.8	19.1	13.9	15.5	45.3	14.5	33.0	20.6	14.8	16.8	15.6	18.9	11.1	18.1	11.6	16.8	15.7	16.5	10.7	16.6	8.3	11.5	12.2	14.1	12.9	16.9	12.7	20.2	15.7	26.4	14.5	27.7	13.8	13.2	12.2	12.3	15.3	17.9	19.5	18.2	17.4	13.8	12.7	15.9	14.7	20.6	18.6	29.3	16.9	10.9	14.1	18.7	22.5	4.3	4.4	9.8	3.9	5.7	3.9	2.3	15.5	11.2	19.0	11.8	12.1	13.0	17.0	7.5	10.9	11.3	10.8	14.2	5.7	16.2	6.6	14.8	12.5	27.4	10.3	12.5	15.8	18.2	12.2	12.8	11.1	13.7	28.8	13.8	12.7	10.8	16.3	13.6	12.5	12.8	22.3	8.9	5.7	8.3	9.0	13.7	7.8	17.1	8.9	10.1	10.7	20.7	6.1	6.4	26.6	13.6	13.0	9.6	16.8	16.1	11.3	13.7	8.0	10.6	15.3	7.2	25.3	8.3	8.9	10.7	5.0	3.2	3.0	3.7	3.9	3.2	4.3	3.6	3.9	4.4	2.9	3.1	2.6	9.8	5.7	2.1	3.0	2.6	2.3	19.1	15.5	33.0	20.6	16.6	8.3	16.9	12.7	13.8	18.6
ERBB3	"HER3, LCCS2"	ENSG00000065361	"Erb-b2 receptor tyrosine kinase 3"	P21860	12	56076799-56103505	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"Hep G2: 31.1;MCF7: 20.3;RT4: 24.3;SK-BR-3: 28.6;SK-MEL-30: 38.1;T-47d: 31.7;WM-115: 40.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"basophil: 5.3"	"Lineage enriched"	"Detected in many"	4	"granulocytes: 5.3"	"Low region specificity"	"Detected in many"							"CAB025331, HPA045396"	Uncertain		Approved	"Plasma membrane,Actin filaments"	"Secreted - unknown location"		420000	"Actin filaments"	"Plasma membrane"	"CAB025331: , HPA045396: "	"unprognostic (2.97e-1)"	"unprognostic (2.71e-2)"	"unprognostic (1.91e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.07e-3)"	"unprognostic (2.31e-3)"	"unprognostic (2.66e-2)"	"unprognostic (9.89e-2)"	"unprognostic (4.30e-2)"	"unprognostic (4.76e-3)"	"unprognostic (5.77e-2)"	"unprognostic (1.06e-2)"	"unprognostic (4.56e-2)"	"unprognostic (1.57e-1)"	"unprognostic (6.72e-3)"	"unprognostic (2.07e-2)"	1.1	1.4	11.6	12.6	16.5	0.6	26.8	2.0	16.7	6.8	40.5	40.3	12.0	37.7	2.8	7.5	29.4	5.7	22.9	3.4	18.6	9.0	16.5	33.9	13.4	0.5	23.5	9.3	0.9	21.5	11.4	1.0	15.4	14.9	16.8	29.7	5.5	36.8	22.3	1.1	30.7	41.3	3.2	27.4	0.5	32.9	1.2	23.8	0.0	4.5	7.4	8.5	11.8	14.4	0.9	0.7	5.3	0.6	1.2	1.2	0.2	10.1	0.6	0.8	0.3	0.0	0.0	16.5	0.8	1.9	1.1	1.1	5.5	18.3	0.0	0.2	0.2	8.6	1.2	1.9	0.6	0.2	0.8	0.0	0.3	31.1	0.0	0.0	0.1	0.4	2.5	0.2	0.0	0.0	0.7	0.3	0.1	20.3	0.1	0.3	2.8	0.4	0.1	1.9	0.5	2.1	24.3	0.9	0.3	0.7	28.6	38.1	31.7	0.1	0.0	0.1	1.1	0.6	0.1	0.3	0.1	0.1	0.1	0.0	40.5	5.3	0.4	0.8	0.9	0.4	0.4	0.4	0.7	0.3	0.3	0.9	0.6	1.2	3.3	1.2	0.6	0.7	0.8	0.2	11.6	16.5	2.0	16.7	18.6	9.0	23.5	9.3	14.9	23.8
ERBB4	"ALS19, HER4"	ENSG00000178568	"Erb-b2 receptor tyrosine kinase 4"	Q15303	2	211375717-212538841	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Lactation, Transcription, Transcription regulation"	"Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"fallopian tube: 24.5"	"Cell line enhanced"	"Detected in some"		"AF22: 9.4;EFO-21: 7.0;HEK 293: 5.2;RPTEC TERT1: 7.7;SCLC-21H: 4.3;T-47d: 6.9"	"Cancer enhanced"	"Detected in many"		"breast cancer: 4.1"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000276, HPA012016, CAB025522"	Enhanced						140000			"CAB000276: , CAB025522: , HPA012016: AB_1846541"	"unprognostic (1.48e-1)"	"unprognostic (3.28e-1)"	"unprognostic (4.31e-3)"	"unprognostic (1.76e-3)"	"unprognostic (3.59e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.88e-1)"	"unprognostic (9.56e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.67e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.61e-1)"	"unprognostic (7.14e-3)"	"unprognostic (1.49e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (4.11e-2)"	1.6	1.9	15.1	1.2	15.0	1.0	13.4	18.6	14.1	7.8	1.1	7.6	8.8	1.1	1.5	1.2	1.3	24.5	1.2	7.0	14.3	6.5	11.9	1.1	2.9	1.2	7.8	10.7	1.3	2.4	10.8	5.1	1.3	8.8	1.7	1.1	2.0	9.7	18.1	3.8	1.8	1.2	1.1	7.3	1.2	1.5	7.6	12.0	0.0	4.5	1.1	1.2	1.4	0.7	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	9.4	0.2	0.0	0.0	0.0	0.0	0.3	0.5	0.1	0.0	0.0	0.0	7.0	1.0	0.4	0.2	0.0	0.0	0.1	5.2	0.0	1.7	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	7.7	0.4	4.3	0.2	0.0	0.1	0.1	6.9	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.1	15.0	18.6	14.1	14.3	6.5	7.8	10.7	8.8	12.0
ERCC2	"EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD"	ENSG00000104884	"ERCC excision repair 2, TFIIH core complex helicase subunit"	P18074	19	45349837-45370918	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005375, HPA038057, HPA069266"	Approved		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB005375: AB_2100152, HPA038057: , HPA069266: "	"unprognostic (1.10e-1)"	"unprognostic (5.48e-1)"	"unprognostic (5.08e-2)"	"unprognostic (9.92e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.41e-1)"	"unprognostic (1.06e-1)"	"prognostic favourable (3.26e-4)"	"unprognostic (3.36e-2)"	"unprognostic (2.44e-3)"	"unprognostic (1.94e-1)"	"unprognostic (5.47e-1)"	"unprognostic (8.99e-2)"	"unprognostic (3.45e-2)"	7.4	15.6	11.4	10.6	17.7	6.7	7.1	9.5	23.8	9.4	8.1	11.7	7.8	7.9	11.7	6.0	6.7	10.0	10.1	7.9	9.4	9.1	8.7	13.2	6.5	9.9	8.2	10.5	9.5	13.1	12.9	10.9	7.2	14.0	8.2	6.4	12.5	9.5	11.8	15.9	10.7	7.1	11.2	5.3	9.7	8.3	17.2	7.8	10.8	10.2	5.1	8.3	9.3	6.6	7.8	17.2	5.0	13.9	11.3	9.8	8.7	12.3	6.0	12.6	17.7	7.5	8.9	6.7	17.6	12.1	22.8	17.5	14.0	8.5	4.4	10.1	17.1	6.4	8.8	14.8	8.7	10.6	14.5	7.5	11.5	14.7	15.9	11.9	13.3	10.2	2.3	26.0	14.8	13.2	18.2	5.0	15.7	6.0	7.0	7.9	5.8	10.6	13.5	8.9	3.7	6.5	10.9	7.4	8.0	15.6	11.1	6.2	10.5	15.8	17.1	21.8	11.9	9.2	39.1	11.6	6.7	6.4	6.4	7.3	9.6	0.0	13.3	5.0	7.7	13.9	9.8	7.8	7.4	7.4	17.2	5.8	7.1	7.4	0.4	11.3	10.9	8.3	7.4	8.7	11.4	17.7	9.5	23.8	9.4	9.1	8.2	10.5	14.0	7.8
ERCC4	"FANCQ, RAD1, XPF"	ENSG00000175595	"ERCC excision repair 4, endonuclease catalytic subunit"	Q92889	16	13920157-13952345	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Disease mutation, Dwarfism, Fanconi anemia, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000156, HPA045828"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Cell Junctions"				"Nucleoplasm, Nuclear bodies"	"Cell Junctions"	"CAB000156: , HPA045828: "	"unprognostic (2.05e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.12e-3)"	"unprognostic (9.41e-2)"	"unprognostic (3.35e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.59e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.49e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.15e-1)"	"unprognostic (6.30e-2)"	"unprognostic (5.88e-4)"	8.4	12.7	8.6	7.0	11.3	5.3	6.4	8.9	9.7	8.1	6.7	9.9	6.0	4.1	8.5	6.8	6.7	8.5	6.8	7.8	7.2	7.1	6.9	7.2	6.9	6.8	10.5	8.8	9.9	7.6	13.3	13.0	5.9	9.6	8.3	5.4	7.1	6.4	7.0	31.3	6.9	5.7	8.5	10.3	7.7	6.6	14.2	8.9	13.7	9.7	5.6	6.4	9.1	7.8	8.4	7.9	8.3	6.8	8.9	7.4	2.6	5.4	7.0	6.4	9.2	10.7	10.1	5.0	7.2	7.7	6.5	8.3	2.4	5.4	9.1	10.4	6.3	6.9	9.5	4.9	10.1	12.3	5.6	4.5	7.8	6.0	9.8	6.0	5.1	7.6	6.9	8.6	7.3	8.6	7.0	10.7	9.1	4.5	8.0	4.1	4.7	3.7	9.2	13.0	11.2	4.0	3.7	5.3	6.3	8.8	7.2	6.7	9.1	4.6	9.7	9.6	7.1	8.6	6.3	9.5	11.1	6.3	9.2	7.3	9.7	8.3	6.2	5.4	6.8	6.8	7.4	6.2	6.4	5.1	5.5	8.4	6.4	6.9	7.2	8.9	5.7	7.9	5.8	2.6	8.6	11.3	8.9	9.7	7.2	7.1	10.5	8.8	9.6	8.9
ERCC5	"ERCM2, XPGC"	ENSG00000134899	"ERCC excision repair 5, endonuclease"	P28715	13	102807146-102876001	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA045845, HPA050126, HPA050374"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"HPA045845: , HPA050126: , HPA050374: "	"unprognostic (1.28e-3)"	"unprognostic (1.32e-3)"	"unprognostic (1.86e-2)"	"unprognostic (9.28e-3)"	"unprognostic (6.19e-2)"	"unprognostic (8.73e-2)"	"unprognostic (1.23e-1)"	"unprognostic (8.72e-2)"	"unprognostic (2.52e-1)"	"unprognostic (2.55e-1)"	"unprognostic (7.77e-3)"	"unprognostic (5.76e-3)"	"prognostic unfavourable (2.96e-6)"	"unprognostic (3.56e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.67e-1)"	"prognostic favourable (6.82e-4)"	22.3	19.1	15.9	16.1	17.8	23.7	20.1	26.4	20.8	19.7	27.0	17.9	27.0	25.0	22.1	25.7	21.0	15.1	21.1	15.4	14.6	13.1	18.7	28.1	19.9	26.4	17.1	16.2	22.9	22.3	15.7	25.6	17.9	19.0	20.1	23.1	15.9	20.5	24.7	14.6	25.8	31.1	17.0	19.4	30.6	21.9	14.0	17.8	40.8	21.8	16.6	26.0	22.4	19.6	10.1	10.8	23.4	17.4	17.7	17.5	12.0	14.7	5.4	10.8	6.7	21.5	20.2	6.5	14.9	19.9	8.7	11.3	8.2	20.6	9.3	7.5	15.1	15.4	9.5	13.7	9.1	14.0	5.3	13.8	15.6	7.2	10.5	28.0	18.0	19.2	13.2	10.0	15.6	15.1	6.4	8.5	15.2	4.0	15.1	19.5	4.6	7.5	8.2	8.0	9.3	17.9	8.2	7.2	10.7	7.8	13.2	8.0	11.8	26.2	15.2	6.7	3.4	5.6	9.4	12.4	3.7	4.7	26.2	11.4	8.4	23.4	9.8	18.3	16.7	12.3	15.5	9.6	15.5	17.5	10.8	10.1	16.6	16.1	7.2	17.7	17.4	7.7	16.6	12.0	15.9	17.8	26.4	20.8	14.6	13.1	17.1	16.2	19.0	17.8
EXT1	"LGCR, LGS, ttv"	ENSG00000182197	"Exostosin glycosyltransferase 1"	Q16394	8	117794490-118111853	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Hereditary multiple exostoses, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 66.4"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 55.1;fHDF/TERT166: 55.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044394	Uncertain						9600000			"HPA044394: AB_10963838"	"unprognostic (1.29e-2)"	"prognostic unfavourable (7.04e-4)"	"unprognostic (2.73e-2)"	"unprognostic (2.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (7.55e-2)"	"unprognostic (1.99e-1)"	"prognostic unfavourable (1.20e-5)"	"unprognostic (1.70e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.31e-2)"	"unprognostic (6.58e-2)"	"unprognostic (1.27e-2)"	"unprognostic (9.84e-2)"	"unprognostic (9.49e-2)"	"prognostic unfavourable (4.64e-4)"	"unprognostic (1.85e-1)"	13.8	11.9	5.8	20.5	4.6	2.1	16.5	7.3	7.4	13.3	17.1	4.1	8.7	23.2	11.5	12.5	11.2	8.8	19.3	14.4	4.6	3.1	8.8	66.4	19.9	8.3	3.0	6.8	10.4	17.9	7.1	6.4	15.6	4.8	9.8	16.0	13.2	9.8	13.3	4.2	12.3	32.0	16.8	4.3	20.1	11.5	5.0	2.7	8.7	12.0	10.3	7.2	11.0	18.5	0.8	1.7	1.2	4.5	0.7	2.4	1.0	17.2	5.0	7.5	2.9	13.6	11.0	3.4	32.3	55.1	23.8	21.9	5.1	1.7	0.3	14.5	55.7	10.9	3.3	18.9	33.5	6.5	5.6	0.6	4.7	4.1	6.4	0.0	1.2	6.9	5.1	28.9	26.6	14.6	0.4	4.8	11.0	1.4	0.8	0.0	2.4	6.4	0.0	2.8	0.5	9.4	6.3	2.3	2.2	4.9	2.3	4.8	3.2	0.2	19.4	20.1	18.4	18.4	9.5	2.7	2.7	1.6	18.6	0.0	5.3	0.3	4.4	0.2	0.2	4.5	1.3	0.8	0.5	0.6	1.0	0.1	0.5	0.9	1.2	0.7	2.2	1.7	2.4	1.0	5.8	4.6	7.3	7.4	4.6	3.1	3.0	6.8	4.8	2.7
EXT2	SOTV	ENSG00000151348	"Exostosin glycosyltransferase 2"	Q93063	11	44095549-44245429	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078409			Supported	"Golgi apparatus"			20000000	"Golgi apparatus"		"HPA078409: "	"unprognostic (5.87e-2)"	"unprognostic (3.05e-3)"	"unprognostic (3.48e-2)"	"unprognostic (3.94e-1)"	"unprognostic (1.42e-1)"	"prognostic unfavourable (2.50e-4)"	"unprognostic (1.77e-3)"	"unprognostic (2.22e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.70e-2)"	"prognostic unfavourable (5.36e-6)"	"unprognostic (7.07e-3)"	"unprognostic (2.97e-1)"	"unprognostic (3.85e-1)"	"unprognostic (1.36e-2)"	24.5	19.5	11.6	17.2	18.5	6.6	25.8	14.5	23.0	26.8	25.0	15.5	17.5	17.6	37.1	25.5	16.7	26.0	23.4	22.7	11.7	13.0	19.2	36.3	22.3	16.8	11.8	12.3	29.3	21.8	25.7	17.3	58.0	16.2	23.7	20.6	22.9	24.7	22.8	16.9	20.2	34.0	35.0	12.2	18.7	19.3	20.0	11.4	16.2	24.7	16.7	13.0	20.2	23.2	6.7	14.9	13.0	12.0	17.8	17.6	9.8	12.9	17.9	9.7	30.2	44.8	33.0	13.4	40.2	50.3	23.8	32.4	12.7	8.9	8.9	18.3	47.0	20.6	10.4	28.5	28.8	17.9	14.3	8.2	9.4	9.7	17.7	8.2	17.8	25.6	18.9	14.4	22.5	33.8	11.0	16.2	17.3	9.9	5.7	5.0	10.4	12.8	7.2	27.8	4.5	13.7	12.3	7.0	7.8	25.4	10.4	6.7	17.3	8.8	30.5	32.2	21.1	31.5	25.7	7.3	9.5	6.5	21.2	6.4	34.3	9.3	11.9	13.0	15.6	12.0	17.6	6.4	12.5	14.4	14.9	6.7	11.9	11.7	2.6	17.8	8.5	5.1	9.6	9.8	11.6	18.5	14.5	23.0	11.7	13.0	11.8	12.3	16.2	11.4
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"Fanconi anemia complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 20.6;testis: 28.8"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm				Nucleoplasm		"HPA063236: "	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"	2.1	2.0	2.2	16.5	3.7	17.1	1.7	5.7	6.6	1.7	5.1	1.1	0.6	5.0	1.7	3.1	6.6	1.9	1.6	1.7	1.8	1.4	2.1	5.8	3.3	11.1	1.3	2.7	1.6	1.8	2.3	1.9	11.2	2.4	1.7	6.3	1.5	2.2	0.5	0.7	5.0	5.4	2.0	1.6	6.9	3.5	28.8	0.8	20.6	1.7	4.6	17.6	2.9	2.5	7.4	6.5	9.9	9.2	7.5	9.5	4.2	9.2	14.2	17.0	14.9	1.1	2.2	13.0	11.5	6.3	19.5	8.2	12.4	15.4	22.7	5.4	3.9	14.2	11.4	8.6	20.6	5.3	19.2	6.7	18.2	25.4	0.7	6.8	7.4	0.7	0.9	15.8	5.0	6.1	16.1	7.0	10.1	21.4	13.6	29.5	11.0	8.9	24.8	13.7	4.1	4.8	8.7	15.3	8.3	17.2	5.1	2.2	9.3	12.3	4.5	15.7	16.5	8.7	12.0	6.3	7.3	22.6	7.4	15.3	14.8	2.6	7.9	9.9	4.7	8.8	3.3	7.4	2.8	4.1	6.5	5.5	0.7	3.0	9.8	7.5	9.2	0.4	9.5	4.2	2.2	3.7	5.7	6.6	1.8	1.4	1.3	2.7	2.4	0.8
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"Fanconi anemia complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 29.7"	"Cell line enhanced"	"Detected in all"		"RH-30: 31.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	6	"basophil: 10.4"	"Lineage enriched"	"Detected in many"	6	"granulocytes: 10.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm				Nucleoplasm		"CAB017793: , HPA030771: "	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favourable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"	4.9	2.7	4.3	8.6	7.0	3.6	4.6	29.7	7.7	4.6	6.4	4.9	5.1	7.1	6.3	4.1	4.5	3.6	5.2	3.2	4.0	2.7	10.0	25.7	6.7	3.7	7.3	1.6	3.3	5.4	2.9	12.1	4.3	6.7	4.4	6.1	4.0	4.0	4.2	4.5	7.7	8.1	2.9	6.4	3.4	4.4	19.6	7.3	7.9	4.3	3.2	6.0	3.5	4.0	1.0	1.3	10.4	1.7	0.3	1.5	0.7	13.4	9.1	12.0	10.5	1.2	3.2	7.6	5.9	3.8	9.4	8.7	10.4	5.7	7.7	4.1	4.3	16.5	12.2	5.1	5.1	7.3	5.7	6.0	10.2	5.3	2.0	6.0	6.8	2.7	2.1	7.5	3.3	5.2	9.0	3.4	6.7	9.5	5.6	3.5	5.8	5.2	12.1	31.2	3.6	3.9	3.5	17.5	9.3	11.1	4.0	3.4	4.1	5.1	2.5	8.3	12.0	9.0	8.3	3.5	6.5	4.0	4.4	5.5	9.7	10.4	0.4	0.0	1.3	0.8	1.3	1.0	0.7	1.5	0.4	1.0	1.2	1.0	0.1	0.3	1.7	1.3	1.3	0.7	4.3	7.0	29.7	7.7	4.0	2.7	7.3	1.6	6.7	7.3
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"Fanconi anemia complementation group D2"	Q9BXW9	3	10026414-10101930	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 24.4;testis: 23.3"	"Cell line enhanced"	"Detected in many"		"BEWO: 45.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"				Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: "	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavourable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"	2.0	1.3	0.8	10.3	2.6	12.2	2.4	1.6	2.7	1.7	2.9	1.1	1.0	2.2	2.2	1.8	4.7	2.4	2.5	1.1	0.8	0.9	2.3	1.0	2.4	9.5	1.3	1.2	3.5	3.5	0.6	1.1	5.3	1.4	2.2	4.9	1.6	3.3	0.4	3.0	3.3	6.2	1.2	2.0	7.3	2.4	23.3	1.6	24.4	1.6	5.6	14.6	2.2	2.4	6.8	3.7	5.3	2.6	2.1	2.9	1.0	8.5	9.1	17.5	4.9	0.9	1.3	45.3	7.9	3.5	11.4	9.3	6.8	8.5	16.8	3.7	2.6	7.5	18.0	6.1	11.4	8.0	12.2	23.0	14.0	6.5	0.1	17.0	14.4	0.4	1.0	12.8	7.1	6.8	14.0	19.3	8.5	9.9	14.2	6.5	21.1	6.4	15.5	14.2	11.9	3.9	9.7	4.9	9.6	9.7	7.6	3.1	11.6	10.8	3.9	9.4	10.8	5.7	11.4	8.2	16.0	28.5	5.4	17.5	16.1	5.3	1.4	3.7	1.5	1.0	1.3	4.9	2.0	1.2	0.9	6.8	2.5	1.9	3.3	2.1	2.6	3.7	2.9	1.0	0.8	2.6	1.6	2.7	0.8	0.9	1.3	1.2	1.4	1.6
FANCE	"FACE, FAE"	ENSG00000112039	"Fanconi anemia complementation group E"	Q9HB96	6	35452361-35467103	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"											CAB014893	Enhanced		Supported	Nucleoplasm				Nucleoplasm		"CAB014893: "	"unprognostic (2.66e-1)"	"unprognostic (8.01e-3)"	"unprognostic (7.73e-2)"	"prognostic unfavourable (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.80e-3)"	"prognostic unfavourable (2.08e-9)"	"unprognostic (8.90e-2)"	"unprognostic (5.70e-3)"	"unprognostic (8.41e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.91e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.05e-1)"	"unprognostic (2.44e-2)"	"unprognostic (5.14e-2)"	7.2	2.1	2.6	7.0	3.8	7.2	8.5	5.5	3.9	6.7	4.1	4.8	1.5	3.1	6.1	4.7	10.0	4.9	5.4	4.1	2.8	3.2	2.4	1.7	5.5	5.4	2.4	1.8	10.8	6.9	2.7	4.0	21.3	3.9	6.7	4.1	3.7	5.3	4.0	20.8	16.8	4.7	4.1	3.7	4.6	3.8	12.1	3.5	3.0	5.9	10.1	8.5	6.7	15.0	2.4	1.8	1.0	1.0	2.6	3.6	0.9	5.6	2.8	7.7	17.3	5.6	10.0	20.7	6.8	5.8	8.9	7.8	6.6	3.2	19.3	4.5	4.2	4.2	8.6	5.8	8.6	6.5	7.5	13.5	6.7	4.3	3.0	7.9	5.5	6.3	17.5	10.9	16.8	5.2	12.4	7.2	7.4	6.6	3.7	9.9	3.2	4.4	10.9	7.3	7.2	2.0	6.2	7.7	7.2	3.9	5.5	6.1	5.4	25.8	3.2	10.8	9.0	6.9	10.6	4.8	16.6	7.0	2.4	14.6	10.1	0.7	1.0	1.0	2.2	0.6	3.0	0.7	2.8	3.6	0.6	2.4	1.9	1.9	0.6	2.6	0.6	1.8	1.7	0.9	2.6	3.8	5.5	3.9	2.8	3.2	2.4	1.8	3.9	3.5
FANCF	FAF	ENSG00000183161	"Fanconi anemia complementation group F"	Q9NPI8	11	22622519-22626787	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 15.2"	"Cell line enhanced"	"Detected in many"		"SCLC-21H: 20.9"	"Low cancer specificity"	"Detected in all"							"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA008899			Supported	Nucleoplasm				Nucleoplasm		"HPA008899: "	"unprognostic (1.16e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.55e-2)"	"unprognostic (8.84e-2)"	"prognostic unfavourable (2.27e-4)"	"unprognostic (4.29e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.74e-3)"	"unprognostic (3.95e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.81e-1)"	"unprognostic (9.14e-2)"	"unprognostic (7.64e-3)"	1.2	4.1	2.9	3.1	2.8	1.1	3.2	1.0	2.7	3.1	3.4			5.3	3.0	6.0	3.0	6.1	1.7	1.9	2.9	3.9	3.2	4.2	1.8	4.9	3.3		4.2	9.0	3.4	4.5	1.5		2.9	3.7		3.8	3.1	0.4	3.1	4.9	1.1	3.5	5.4	4.6	4.3			3.6		4.8	2.6	2.0	15.2	9.7	11.5	5.7	10.0	15.1	7.3	1.4	4.3	5.6	6.1	2.9	3.5	2.3	2.8	3.3	3.2	3.5	2.8	2.2	7.2	0.7	2.8	6.2	4.5	4.6	1.6	11.7	2.1	2.7	1.8	4.9	3.4	4.9	2.9	3.4	9.0	1.1	4.9	5.0	6.8	9.4	2.0	4.5	12.5	4.6	6.4	5.4	10.9	2.6	8.0	6.0	5.6	20.9	9.8	1.5	4.9	4.8	9.9	4.5	3.6	3.3	3.5	5.9	4.0	5.4	6.9	2.1	5.4	2.0	7.6	5.7	5.4	11.5	11.5	5.5	13.5	11.8	10.8	10.8	6.4	15.2	15.1	12.4	0.8	10.0	5.7	9.7	7.3	7.3										
FANCG	"FAG, XRCC9"	ENSG00000221829	"Fanconi anemia complementation group G"	O15287	9	35073835-35080016	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008105, HPA045335"	Approved		Supported	"Nucleoli,Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"	Nucleoli	"CAB008105: AB_2231542, HPA045335: "	"unprognostic (9.41e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.83e-3)"	"prognostic unfavourable (2.02e-4)"	"unprognostic (8.92e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.27e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.62e-2)"	"prognostic unfavourable (2.38e-7)"	"unprognostic (1.14e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.10e-1)"	5.8	5.0	4.4	7.1	6.5	14.9	7.5	13.9	8.5	6.2	5.9	5.3	8.4	6.7	6.8	3.2	9.2	8.6	4.7	5.9	7.6	4.0	5.2	4.5	5.1	9.9	8.7	4.4	9.2	17.0	6.7	4.8	7.6	6.6	7.0	5.5	3.5	8.7	9.7	2.9	8.9	6.5	6.4	4.2	8.6	5.8	8.9	7.6	25.6	9.3	4.8	9.2	6.8	6.9	6.8	4.8	8.9	2.5	8.8	9.2	3.4	15.7	19.5	14.3	13.2	3.2	5.1	12.0	11.1	8.0	21.8	20.9	9.3	9.9	15.6	7.7	3.5	9.7	11.9	10.2	8.3	18.2	7.2	11.1	20.9	5.7	0.9	11.3	12.9	4.2	2.0	19.0	8.6	11.1	7.3	21.0	10.9	14.0	19.1	15.5	14.9	15.1	19.8	16.9	11.0	5.1	6.7	6.9	12.6	7.3	10.4	4.1	13.5	8.1	6.7	10.3	20.7	13.2	14.9	5.7	10.8	9.4	9.2	8.4	14.1	8.9	0.8	7.7	7.4	2.5	6.5	6.8	6.1	5.7	2.2	6.5	4.8	5.0	1.3	8.8	2.3	4.8	9.2	3.4	4.4	6.5	13.9	8.5	7.6	4.0	8.7	4.4	6.6	7.6
FAT1	"CDHF7, CDHR8, FAT"	ENSG00000083857	"FAT atypical cadherin 1"	Q14517	4	186587783-186726722	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 76.4"	"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 63.5;LHCN-M2: 46.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001869, HPA023882"	Enhanced				"Intracellular and membrane"		120000			"HPA001869: AB_1078818, HPA023882: AB_1848429"	"unprognostic (1.98e-1)"	"unprognostic (4.91e-2)"	"unprognostic (2.50e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.53e-2)"	"unprognostic (5.82e-3)"	"unprognostic (2.31e-1)"	"prognostic unfavourable (4.22e-4)"	"unprognostic (6.10e-2)"	"unprognostic (3.05e-2)"	"unprognostic (1.15e-3)"	"unprognostic (6.80e-2)"	"unprognostic (3.57e-2)"	"unprognostic (8.03e-3)"	"unprognostic (9.41e-2)"	"unprognostic (6.25e-3)"	"unprognostic (4.27e-2)"	15.5	1.3	7.9	12.3	9.8	0.4	15.4	11.9	8.4	15.9	40.4	11.8	8.1	17.9	20.6	14.0	9.7	9.6	28.2	21.1	10.0	6.0	29.1	13.3	10.9	1.4	11.4	6.2	9.7	13.8	7.5	10.5	14.6	24.7	15.9	22.9	5.0	13.9	18.2	3.0	13.1	76.4	18.3	12.8	1.7	11.5	7.0	11.2	1.3	10.5	10.2	6.7	17.5	9.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.8	18.6	18.4	0.0	18.5	22.3	4.5	24.8	41.0	12.1	7.7	11.0	11.0	0.0	6.0	63.5	9.0	7.2	30.6	16.5	0.0	2.9	0.0	6.6	11.1	9.2	8.0	6.6	8.0	11.1	22.5	14.7	0.2	0.1	0.0	46.6	5.9	14.3	0.0	4.1	3.1	0.0	5.1	0.3	18.2	17.5	1.9	7.4	4.3	7.3	2.9	0.0	2.9	5.3	34.6	13.4	0.4	15.4	0.1	0.0	0.1	7.9	0.0	11.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.9	9.8	11.9	8.4	10.0	6.0	11.4	6.2	24.7	11.2
FAT4	"CDHF14, CDHR11, FAT-J"	ENSG00000196159	"FAT atypical cadherin 4"	Q6V0I7	4	125316399-125492932	"Cancer-related genes, Disease related genes, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Deafness, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"ASC diff: 12.1;ASC TERT1: 9.0;fHDF/TERT166: 8.8;HSkMC: 10.4;HUVEC TERT2: 10.9;TIME: 17.1"	"Low cancer specificity"	"Detected in many"							"Cell type enriched"	"Detected in single"	12	"NK-cell: 1.1"	"Lineage enriched"	"Detected in single"	12	"NK-cells: 1.1"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA052819	Approved		Approved	Cytosol			7900000	Cytosol		"HPA052819: "	"unprognostic (1.18e-1)"	"unprognostic (1.77e-1)"	"unprognostic (7.99e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.31e-1)"	"unprognostic (2.81e-4)"	"unprognostic (6.17e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.77e-2)"	"unprognostic (2.78e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.39e-1)"	"prognostic favourable (1.89e-4)"	"unprognostic (2.38e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.30e-2)"	"unprognostic (2.49e-3)"	3.8	0.5	0.9	0.8	0.7	0.0	3.2	0.0	0.5	4.4	7.1			0.3	2.7	0.6	1.9	2.1	4.1	5.0	1.0	0.4	2.6	2.0	5.3	0.1	0.9		5.3	0.5	6.7	0.4	2.5		3.6	1.9		1.0	2.3	1.1	1.4	2.4	3.3	0.6	2.1	2.4	0.1			3.9		0.2	3.0	2.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.7	5.9	0.6	12.1	9.0	0.0	2.0	2.3	0.9	1.0	0.0	0.3	0.0	2.4	8.8	0.0	2.2	2.5	0.6	0.0	1.0	1.3	2.5	0.0	3.9	0.8	0.0	10.4	1.3	0.5	5.5	10.9	0.0	1.6	5.0	0.1	0.4	0.0	0.4	0.2	0.7	1.2	0.0	0.1	0.0	0.1	1.2	0.3	0.0	0.0	0.0	0.0	17.1	6.0	1.7	2.1	0.9	0.2	0.0	0.0	1.6	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0										
FBXW7	"AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10"	ENSG00000109670	"F-box and WD repeat domain containing 7"	Q969H0	4	152320544-152536063	"Cancer-related genes, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 60.1;skin 1: 45.0"	"Cell line enhanced"	"Detected in all"		"U-266/70: 37.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013793, CAB029987"	Supported		Supported	Nucleoplasm,Vesicles				"Nucleoplasm, Vesicles"		"CAB013793: AB_2533451, CAB029987: AB_2246842"	"unprognostic (3.32e-1)"	"unprognostic (9.02e-2)"	"unprognostic (1.84e-2)"	"unprognostic (3.08e-2)"	"unprognostic (3.87e-1)"	"unprognostic (1.36e-3)"	"unprognostic (4.37e-1)"	"unprognostic (1.94e-1)"	"unprognostic (8.28e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.32e-3)"	"unprognostic (3.19e-2)"	"prognostic unfavourable (1.52e-4)"	"unprognostic (3.38e-2)"	"unprognostic (1.41e-1)"	"unprognostic (5.49e-3)"	"unprognostic (2.17e-3)"	9.2	6.8	27.0	8.9	27.9	11.1	9.8	27.2	60.1	5.5	6.1	3.6	3.8	4.9	6.0	18.3	9.8	10.6	6.3	10.9	21.4	10.1	4.1	7.3	6.9	9.8	9.1	40.5	6.4	8.0	6.4	7.3	6.2	37.2	5.1	6.9	2.8	7.6	5.3	15.8	45.0	6.5	6.1	6.4	10.1	8.0	13.7	5.7	6.5	6.8	10.6	12.3	7.9	6.5	2.9	2.2	16.6	3.4	7.8	5.0	1.3	4.9	3.9	10.2	7.4	7.1	5.1	8.4	7.1	6.5	4.4	4.2	7.9	6.3	12.7	2.0	6.8	2.9	8.7	16.0	6.2	7.2	4.1	5.9	4.8	5.6	7.2	14.4	5.4	8.1	25.3	7.6	12.9	7.7	9.3	13.6	5.5	6.9	16.5	5.7	5.0	3.1	16.6	4.3	2.5	5.4	8.5	6.5	5.6	4.5	6.2	3.9	3.4	6.8	8.1	6.0	6.8	3.1	4.0	37.4	21.3	12.4	4.8	4.7	4.3	16.6	3.1	1.7	5.0	3.4	3.3	2.9	3.7	3.2	1.8	2.4	3.9	3.2	5.5	7.8	2.5	2.2	3.3	1.3	27.0	27.9	27.2	60.1	21.4	10.1	9.1	40.5	37.2	5.7
FH	fumarase	ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519761	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 93.4"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria			2800000	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favourable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	14.3	28.1	15.7	10.4	20.2	9.3	13.3	15.7	24.4	10.5	22.7	9.9	16.7	23.2	13.7	10.7	17.7	10.3	9.5	59.0	22.9	13.9	35.0	93.4	9.9	13.3	15.2	19.4	9.4	13.9	25.2	11.4	14.3	18.4	12.3	24.4	10.2	18.4	20.6	65.1	13.4	21.4	14.7	14.4	11.1	17.5	14.0	11.7	13.8	12.3	45.2	13.4	13.4	11.2	16.0	26.4	4.5	18.8	10.4	13.9	8.9	29.2	24.5	23.3	21.0	22.9	27.0	36.9	36.3	28.5	41.0	25.8	35.1	18.3	18.6	24.1	27.8	41.7	35.6	27.0	35.8	21.2	11.5	17.4	26.0	29.9	20.5	40.7	15.9	19.5	16.8	23.0	26.0	25.2	53.0	24.1	29.8	14.6	35.1	27.2	24.7	52.7	29.0	25.5	83.5	39.5	24.9	30.0	25.9	30.6	36.3	23.2	27.6	27.7	24.7	18.4	23.8	32.5	60.5	21.6	23.1	22.6	20.6	46.8	26.4	4.5	12.8	2.7	9.7	18.8	12.6	16.0	11.4	9.0	26.4	14.1	13.9	12.7	0.7	10.4	15.7	13.2	13.2	8.9	15.7	20.2	15.7	24.4	22.9	13.9	15.2	19.4	18.4	11.7
FLCN	"BHD, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"				Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favourable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	11.9	15.3	23.6	10.8	41.6	15.6	13.9	49.4	26.9	18.0	21.3	18.5	10.4	25.0	22.1	15.8	11.0	14.5	17.6	17.2	17.2	8.6	9.6	15.5	15.6	11.6	24.2	13.5	25.2	13.7	6.1	20.3	13.3	18.1	15.4	10.7	14.8	10.5	14.8	22.7	12.6	20.2	15.4	14.8	16.5	15.3	12.5	29.1	6.6	15.8	3.9	8.0	15.0	14.8	6.0	2.4	10.5	6.8	4.5	5.0	3.1	6.4	15.7	5.8	7.5	18.9	10.8	8.5	5.8	9.7	9.2	12.8	11.9	5.4	3.2	8.1	7.0	7.5	7.0	3.6	4.8	6.1	5.9	6.5	4.6	6.8	17.5	2.4	18.3	15.8	12.4	14.4	10.7	7.5	8.9	8.3	8.8	8.3	4.3	4.1	5.9	3.9	8.6	26.8	3.7	5.5	7.1	7.0	4.5	6.1	3.7	10.1	5.6	4.5	8.8	21.7	9.4	29.9	7.6	4.1	3.9	3.0	13.7	5.5	8.5	3.6	4.7	2.8	2.9	6.8	4.1	5.3	3.5	2.5	2.4	6.0	3.9	3.4	10.5	4.5	2.2	2.4	5.0	3.1	23.6	41.6	49.4	26.9	17.2	8.6	24.2	13.5	18.1	29.1
FUBP1	"FBP, FUBP"	ENSG00000162613	"Far upstream element binding protein 1"	Q96AE4	1	77944055-77979110	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006149	Supported		Enhanced	Nucleoplasm			200000	Nucleoplasm		"HPA006149: AB_1849172"	"unprognostic (4.17e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.35e-3)"	"unprognostic (3.89e-2)"	"unprognostic (3.77e-1)"	"unprognostic (5.65e-2)"	"prognostic unfavourable (9.83e-9)"	"unprognostic (2.32e-2)"	"unprognostic (2.16e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.31e-3)"	"unprognostic (9.80e-3)"	"unprognostic (9.02e-3)"	"unprognostic (1.37e-1)"	"unprognostic (1.67e-1)"	"unprognostic (6.24e-2)"	"unprognostic (9.46e-2)"	23.9	35.5	21.8	42.4	26.9	56.8	27.0	34.0	31.8	24.3	19.6	18.1	23.0	21.8	29.4	35.0	23.5	25.2	18.4	27.5	22.0	22.3	26.6	16.3	27.2	37.6	17.5	28.8	44.4	31.6	36.0	41.5	27.3	26.3	22.4	28.3	22.0	28.2	35.6	27.4	21.3	24.0	22.7	31.3	28.6	22.6	17.6	19.9	64.9	35.0	26.2	40.3	24.0	29.1	16.1	11.3	10.8	16.1	23.5	22.2	12.8	21.8	19.2	45.6	18.1	7.1	8.9	37.4	22.6	13.5	21.7	15.8	19.5	24.4	39.1	10.6	16.8	21.8	30.5	24.9	29.1	43.0	15.5	25.0	32.0	28.6	15.3	42.8	10.5	11.7	20.6	23.2	18.4	17.3	28.6	17.4	17.1	22.1	34.0	20.7	35.6	13.8	41.7	36.1	15.0	22.5	21.5	24.1	22.7	21.0	19.9	17.8	24.3	15.5	22.2	21.0	30.7	5.9	27.0	16.7	18.0	50.7	9.1	18.9	21.4	3.8	9.6	10.8	18.7	15.7	22.2	16.1	18.3	19.4	8.7	13.1	17.9	20.9	4.0	23.5	16.1	11.3	21.3	12.8	21.8	26.9	34.0	31.8	22.0	22.3	17.5	28.8	26.3	19.9
GATA3	HDR	ENSG00000107485	"GATA binding protein 3"	P23771	10	8045378-8075203	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Immunity, Innate immunity, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Deafness, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"seminal vesicle: 97.8;skin 1: 61.7"	"Cell line enhanced"	"Detected in some"		"BEWO: 32.6;MCF7: 77.8;RT4: 31.8;SH-SY5Y: 27.3;T-47d: 101.3"	"Group enriched"	"Detected in many"	24	"breast cancer: 190.0;urothelial cancer: 87.0"	"Low region specificity"	"Detected in single"			"Group enriched"	"Detected in many"	42	"gdT-cell: 9.7;MAIT T-cell: 13.3;memory CD4 T-cell: 18.2;memory CD8 T-cell: 14.1;naive CD4 T-cell: 10.0;naive CD8 T-cell: 9.0;NK-cell: 16.6;T-reg: 18.9"	"Group enriched"	"Detected in many"	54	"NK-cells: 16.6;T-cells: 18.9"	"Region enriched"	"Detected in single"	6	"midbrain: 7.3"	"Group enriched"	"Detected in some"	46	"midbrain: 25.5;pons and medulla: 17.5;thalamus: 20.0"	"CAB016217, HPA029730"	Enhanced		Supported	Nucleoplasm				Nucleoplasm		"CAB016217: AB_2108591, HPA029730: AB_10601907"	"unprognostic (1.70e-1)"	"unprognostic (7.23e-2)"	"unprognostic (3.58e-2)"	"unprognostic (2.00e-1)"	"unprognostic (7.03e-3)"	"unprognostic (4.68e-3)"	"unprognostic (4.23e-2)"	"unprognostic (9.65e-2)"	"unprognostic (2.06e-1)"	"unprognostic (2.55e-1)"	"unprognostic (3.83e-1)"	"unprognostic (1.17e-1)"	"prognostic unfavourable (3.13e-4)"	"unprognostic (1.48e-1)"	"unprognostic (5.16e-2)"	"unprognostic (6.31e-2)"	"unprognostic (1.82e-3)"	2.0	2.0	0.3	3.4	0.3	0.9	17.8	0.3	0.3	1.8	0.5	0.1	44.4	0.1	0.4	13.5	0.8	0.4	0.4	0.9	0.3	0.4	12.9	0.7	1.6	2.7	0.8	0.0	0.3	0.4	55.0	3.8	53.4	1.4	8.1	0.0	1.8	8.9	97.8	0.8	61.7	1.2	3.4	0.4	2.7	0.5	0.8	0.1	42.4	3.3	0.6	3.4	26.9	16.4	0.2	0.0	0.3	0.0	16.6	18.9	3.0	5.4	1.3	0.0	0.0	0.0	0.0	32.6	0.1	0.0	0.0	0.0	2.0	4.9	0.0	0.0	0.0	4.7	0.5	0.1	0.0	15.6	1.6	0.0	0.0	0.0	0.3	0.0	0.0	0.0	1.1	0.0	0.3	2.5	0.0	0.0	0.0	77.8	8.5	0.0	0.5	0.7	0.4	0.4	0.1	0.0	31.8	1.6	27.3	0.0	4.4	0.0	101.3	0.0	0.0	0.4	1.0	0.2	0.6	0.1	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	9.7	0.0	13.3	0.2	18.2	14.1	0.0	0.0	10.0	9.0	0.3	16.6	0.0	0.0	18.9	3.0	0.3	0.3	0.3	0.3	0.3	0.4	0.8	0.0	1.4	0.1
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985895	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 262.7"	"Group enriched"	"Detected in some"	8	"HAP1: 53.1;Hep G2: 209.8"	"Cancer enhanced"	"Detected in all"		"liver cancer: 269.0"	"Low region specificity"	"Detected in some"			"Group enriched"	"Detected in some"	4	"naive CD4 T-cell: 5.0;naive CD8 T-cell: 3.5;NK-cell: 1.7"	"Group enriched"	"Detected in many"	12	"NK-cells: 1.7;T-cells: 5.0"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA006316			Supported	"Plasma membrane"	"Intracellular and membrane"			"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavourable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"	30.1	5.9	0.4	3.6	0.7	0.0	50.2	0.6	0.4	3.3	4.5	0.5	2.2	0.5	2.5	11.7	2.0	3.4	9.2	8.0	0.4	1.1	21.2	1.1	37.0	1.9	1.6	0.4	6.0	4.6	0.3	16.9	262.7	1.6	3.6	1.0	6.3	3.8	2.3	4.1	5.5	1.8	3.3	2.1	0.9	4.0	2.1	0.3	2.3	7.2	11.2	3.0	7.6	8.0	0.0	0.2	0.0	0.0	1.7	5.0	0.6	0.0	0.0	2.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.4	0.0	0.0	0.0	0.0	0.0	53.1	0.0	0.0	0.0	2.4	0.0	0.1	209.8	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.1	0.0	0.0	0.0	0.0	14.5	0.6	1.7	4.3	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.8	0.5	0.2	0.0	5.0	3.5	0.0	1.7	0.0	0.0	0.0	0.6	0.4	0.7	0.6	0.4	0.4	1.1	1.6	0.4	1.6	0.3
GRIN2A	"GluN2A, NMDAR2A"	ENSG00000183454	"Glutamate ionotropic receptor NMDA type subunit 2A"	Q12879	16	9753404-10182754	"Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters"	"Ion transport, Transport"	"Ion channel, Ligand-gated ion channel, Receptor"	"Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"brain: 25.2"	"Cell line enhanced"	"Detected in some"		"fHDF/TERT166: 7.7;RPMI-8226: 2.9;U-138 MG: 8.4"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			CAB022725	Enhanced									"CAB022725: "	"unprognostic (6.43e-2)"	"unprognostic (2.47e-1)"	"unprognostic (5.97e-2)"	"unprognostic (3.21e-2)"	"unprognostic (3.13e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.08e-1)"	"unprognostic (5.39e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.75e-3)"	"unprognostic (4.79e-3)"	"unprognostic (2.05e-1)"	"unprognostic (3.92e-3)"	"unprognostic (3.33e-2)"	0.9	1.0	5.4	0.5	5.9	0.4	0.6	8.5	25.2	0.6	0.7	1.5	0.0	0.9	0.8	4.5	2.1	4.1	0.5	4.0	8.0	1.9	0.9	0.4	1.0	0.5	1.7	10.3	0.5	0.6	0.4	0.3	0.4	1.4	0.5	0.7	1.4	0.7	1.0	0.5	1.2	0.7	0.9	1.2	0.4	1.1	5.2	0.8	0.0	0.8	0.0	0.7	0.6	0.5	0.6	0.0	0.3	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.1	1.8	0.5	1.4	0.0	0.1	0.0	0.0	7.7	0.1	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	2.9	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	8.4	0.8	0.0	0.1	0.0	0.0	0.0	1.2	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.6	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	5.4	5.9	8.5	17.9	8.0	1.9	1.7	10.3	1.4	0.8
HIF1A	"bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8"	ENSG00000100644	"Hypoxia inducible factor 1 alpha subunit"	Q16665	14	61695513-61748259	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"LHCN-M2: 117.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"eosinophil: 47.8"	"Lineage enriched"	"Detected in all"	6	"granulocytes: 47.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000907, HPA001275, CAB017442"	Supported		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane"				"Nucleoplasm, Nuclear bodies"	"Plasma membrane"	"CAB017442: AB_10621732, HPA000907: , HPA001275: AB_1079057"	"unprognostic (1.07e-2)"	"unprognostic (1.13e-3)"	"unprognostic (9.41e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.51e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.94e-3)"	"unprognostic (3.40e-1)"	"unprognostic (4.05e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.77e-2)"	"unprognostic (8.39e-2)"	"unprognostic (1.24e-1)"	"unprognostic (3.23e-2)"	"unprognostic (3.58e-1)"	"unprognostic (7.35e-2)"	"unprognostic (3.88e-2)"	31.9	62.0	15.6	45.2	17.8	125.2	24.9	22.7	18.5	45.7	15.3	12.3	23.5	10.8	17.7	31.3	31.2	21.7	50.0	19.4	17.5	16.5	76.4	42.7	42.8	27.3	18.3	11.0	34.5	12.7	13.7	26.8	24.2	25.1	17.6	13.9	14.0	24.6	36.2	8.0	17.4	16.9	18.7	27.2	57.3	16.0	21.1	12.4	24.7	26.9	18.4	28.8	37.8	21.5	6.6	6.0	47.8	6.8	6.2	7.9	5.1	37.6	15.0	15.1	43.2	24.0	38.7	20.5	31.3	37.8	39.5	35.6	6.5	12.5	9.2	23.6	38.7	8.9	9.7	51.5	49.4	4.0	5.0	5.6	13.8	11.2	53.6	2.3	6.2	67.6	16.3	28.9	31.0	24.8	3.8	0.0	117.8	7.8	7.3	2.9	13.6	19.8	0.5	34.0	2.7	50.9	25.1	12.7	14.1	58.8	8.4	20.7	8.8	4.5	14.7	89.7	20.1	29.7	26.3	4.9	7.2	10.4	47.3	4.7	24.2	11.2	6.8	47.8	3.8	5.5	4.9	6.5	5.0	4.4	6.0	6.6	7.9	5.1	18.2	6.2	5.6	2.9	3.4	5.1	15.6	17.8	22.7	13.2	17.5	16.5	18.3	11.0	25.1	12.4
KDM5C	"DXS1272E, JARID1C, MRX13, SMCX, XE169"	ENSG00000126012	"Lysine demethylase 5C"	P41229	X	53191321-53225422	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038244, HPA046147"			Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA038244: , HPA046147: "	"unprognostic (1.19e-1)"	"unprognostic (1.13e-1)"	"unprognostic (1.56e-2)"	"unprognostic (7.10e-2)"	"unprognostic (9.75e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavourable (2.11e-4)"	"unprognostic (2.08e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.24e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.58e-2)"	"unprognostic (5.05e-3)"	"unprognostic (1.96e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.00e-1)"	19.5	22.9	22.4	22.6	24.7	26.3	17.9	43.0	31.7	25.9	19.5	23.4	16.7	22.2	29.2	13.3	26.9	24.8	15.2	17.6	21.6	15.3	17.0	18.8	20.6	25.8	24.6	21.8	33.1	22.5	37.7	31.8	34.0	22.8	18.7	13.5	17.0	25.6	17.1	36.6	28.4	22.2	23.6	16.0	25.0	19.4	10.6	26.2	29.0	22.2	11.3	24.5	21.5	26.4	4.5	4.3	4.8	4.0	2.8	6.1	3.8	17.3	23.8	25.5	19.5	17.7	16.2	18.1	10.9	12.8	14.8	13.8	16.0	11.4	16.2	14.2	14.3	15.6	28.8	23.3	11.3	12.1	42.6	15.7	25.3	11.3	21.8	18.6	31.4	12.7	17.2	28.9	35.6	21.8	30.6	10.8	10.8	22.3	13.6	20.9	21.6	22.3	15.4	15.2	17.6	9.4	16.7	19.2	24.8	33.1	30.7	12.4	21.5	16.4	14.9	16.5	14.3	14.8	10.5	15.7	12.8	12.4	21.4	22.1	12.2	3.0	3.8	2.7	6.1	3.6	5.1	4.5	3.7	5.7	3.1	3.2	4.5	2.9	4.8	2.8	4.0	4.3	4.3	3.8	22.4	24.7	43.0	31.7	21.6	15.3	24.6	21.8	22.8	26.2
KDM6A	UTX	ENSG00000147050	"Lysine demethylase 6A"	O15550	X	44873177-45112602	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000568, HPA001165, HPA002111"	Enhanced		Approved	Nucleoplasm,Nucleoli	"Intracellular and membrane"			Nucleoplasm	Nucleoli	"HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704"	"unprognostic (1.73e-3)"	"unprognostic (6.86e-3)"	"unprognostic (1.45e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.58e-3)"	"unprognostic (8.22e-3)"	"unprognostic (3.23e-1)"	"unprognostic (2.44e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.07e-1)"	"unprognostic (2.73e-1)"	"unprognostic (2.24e-2)"	"unprognostic (5.18e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.16e-2)"	12.3	12.1	16.5	17.6	24.5	47.9	21.4	26.1	22.0	16.9	11.8	16.7	12.0	13.1	22.6	11.3	15.4	16.9	15.2	9.1	18.2	6.5	11.6	13.5	19.7	15.1	28.8	11.3	23.8	14.9	21.3	20.2	13.3	18.3	10.3	11.3	10.3	16.1	12.6	15.1	21.3	17.6	13.5	14.9	18.1	15.0	17.7	26.1	19.1	14.5	6.9	13.6	14.9	22.8	5.5	7.1	15.7	7.5	6.2	7.9	3.5	8.9	7.8	11.6	11.7	8.3	8.6	24.9	7.0	5.0	8.4	8.8	18.4	7.7	5.9	3.8	6.5	19.3	14.8	12.3	7.8	8.5	15.9	7.3	9.9	6.8	5.9	3.9	20.7	4.6	10.2	13.8	14.5	6.5	10.1	14.6	5.2	5.8	8.1	11.5	9.7	9.0	9.0	11.1	1.0	4.8	16.8	10.0	5.4	22.3	11.2	9.5	10.8	0.1	5.5	8.0	6.2	8.0	3.6	9.2	11.1	8.9	5.6	4.1	4.6	15.7	3.8	3.5	5.3	7.5	6.0	5.5	7.2	7.9	7.1	3.8	7.0	6.3	7.3	6.2	7.2	3.8	5.6	3.5	16.5	24.5	26.1	22.0	18.2	6.5	28.8	11.3	18.3	26.1
KEAP1	"INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454"	ENSG00000079999	"Kelch like ECH associated protein 1"	Q14145	19	10486120-10503741	"Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins"	"Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005558, CAB025337"	Approved		Supported	"Nucleoplasm,Centriolar satellite,Cytosol"				"Nucleoplasm, Centriolar satellite"	Cytosol	"CAB025337: , HPA005558: AB_1079175"	"unprognostic (1.98e-1)"	"prognostic favourable (3.28e-4)"	"unprognostic (1.61e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.42e-1)"	"unprognostic (1.63e-2)"	"unprognostic (2.64e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.48e-1)"	"unprognostic (5.22e-3)"	"unprognostic (2.04e-1)"	"unprognostic (9.99e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.71e-3)"	"unprognostic (5.06e-1)"	"unprognostic (8.18e-2)"	"unprognostic (1.60e-2)"	16.0	13.7	13.5	10.4	14.3	9.1	12.4	13.2	15.1	13.1	15.7	15.4	13.8	13.6	11.0	12.7	26.3	15.1	12.7	19.7	13.9	13.7	13.2	22.0	10.8	15.5	16.7	7.4	11.8	14.3	11.1	10.2	11.5	14.3	13.9	8.8	11.8	11.3	13.9	63.9	16.8	13.8	11.6	16.5	11.3	10.6	12.2	13.8	13.1	14.5	29.1	16.1	14.5	11.2	14.6	23.7	21.3	19.8	21.0	30.8	19.6	17.2	31.7	8.8	11.7	18.1	15.5	9.4	14.7	11.0	15.1	13.6	22.5	17.4	24.6	38.8	16.3	15.5	17.4	11.5	7.5	23.8	19.1	37.2	9.4	26.6	17.5	19.4	20.2	16.0	15.6	17.0	7.9	14.3	22.7	45.6	13.1	23.9	14.1	53.4	25.6	26.7	25.6	11.0	28.7	9.8	20.7	24.2	12.6	20.5	13.8	12.7	11.9	26.0	17.6	24.4	13.1	27.3	17.8	26.6	33.3	24.1	18.8	23.2	17.9	16.1	19.8	21.3	30.8	17.0	29.3	14.6	21.5	28.3	23.7	5.7	13.5	19.1	10.9	21.0	16.6	16.3	25.4	19.6	13.5	14.3	13.2	12.8	13.9	13.7	16.7	7.4	14.3	13.8
KLF6	"BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9"	ENSG00000067082	"Kruppel like factor 6"	Q99612	10	3775996-3785281	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013529, HPA069585"	Supported		Approved	"Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol"				"Nucleoplasm, Nucleoli fibrillar center"	"Vesicles, Cytosol"	"CAB013529: AB_2533431, HPA069585: "	"unprognostic (1.23e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.47e-3)"	"unprognostic (4.53e-2)"	"unprognostic (1.47e-1)"	"unprognostic (7.55e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.08e-3)"	"unprognostic (1.61e-1)"	"unprognostic (2.83e-2)"	"unprognostic (1.36e-2)"	"unprognostic (2.35e-2)"	"prognostic favourable (2.28e-4)"	"unprognostic (8.07e-3)"	"unprognostic (4.85e-2)"	"unprognostic (6.87e-2)"	"unprognostic (1.37e-2)"	69.8	10.0	8.4	26.3	10.6	80.6	101.1	7.4	10.1	28.6	31.7	10.3	9.7	11.0	24.9	28.8	38.6	28.0	38.6	18.6	7.8	5.1	32.2	32.5	46.0	35.8	13.8	4.2	20.2	23.8	7.5	4.7	26.1	11.2	20.1	21.0	13.2	26.9	16.5	57.8	60.2	44.8	42.8	17.0	20.3	26.7	14.3	10.0	12.5	41.0	28.8	21.5	44.7	30.7	15.6	29.8	77.8	18.7	13.0	30.8	23.2	13.0	3.5	6.8	2.2	39.6	39.8	4.3	22.5	11.5	24.1	16.4	9.1	17.6	3.7	5.2	24.3	7.9	4.2	20.7	20.1	18.3	2.5	0.5	4.1	8.6	17.0	2.4	12.9	13.1	39.6	17.1	32.7	24.5	4.1	29.2	30.5	0.9	4.5	3.8	2.5	6.4	3.0	7.0	13.1	23.6	13.0	3.0	2.9	5.5	16.0	33.7	7.9	2.0	31.9	32.5	4.5	19.2	10.3	5.6	18.2	6.9	8.7	3.3	10.0	50.9	17.0	43.7	27.1	14.2	23.9	15.6	30.8	26.8	13.1	12.5	9.6	14.8	77.8	13.0	18.7	29.8	22.2	23.2	8.4	10.6	7.4	10.1	7.8	5.1	13.8	4.2	11.2	10.0
KMT2C	"HALR, KIAA1506, MLL3"	ENSG00000055609	"Lysine methyltransferase 2C"	Q8NEZ4	7	152134922-152436005	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA074736			Approved	Nucleoplasm				Nucleoplasm		"HPA074736: "	"unprognostic (7.75e-2)"	"unprognostic (3.10e-1)"	"unprognostic (2.83e-1)"	"unprognostic (1.33e-2)"	"unprognostic (1.31e-1)"	"unprognostic (5.23e-3)"	"unprognostic (1.09e-1)"	"unprognostic (1.59e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.17e-1)"	"unprognostic (3.45e-1)"	"unprognostic (1.06e-1)"	"prognostic favourable (8.01e-6)"	"unprognostic (1.78e-1)"	"unprognostic (3.83e-1)"	"unprognostic (3.04e-2)"	"unprognostic (2.64e-1)"	13.9	12.6	11.7	16.7	18.6	29.7	14.5	24.8	14.1	18.4	12.6	15.5	21.4	9.7	20.2	20.6	14.4	12.8	12.7	10.8	13.4	9.5	10.3	11.4	13.0	12.1	17.7	9.4	18.8	18.4	18.8	18.9	38.0	12.6	14.0	11.8	12.6	15.8	22.9	30.3	25.2	13.1	13.6	16.0	14.6	14.9	13.6	19.6	22.6	16.9	9.3	16.8	17.8	31.6	5.6	3.5	16.1	3.9	5.5	2.9	0.6	9.5	4.8	9.0	9.5	16.2	9.8	10.5	5.0	3.8	4.0	4.9	9.1	5.8	15.2	7.3	9.1	5.5	9.6	7.3	6.7	9.6	4.9	9.0	7.2	6.3	7.9	15.3	11.1	8.2	10.1	5.7	7.6	5.7	14.5	13.2	8.7	13.3	11.0	13.9	5.4	4.8	7.4	8.1	7.9	6.9	9.9	13.1	10.3	8.2	14.7	5.4	4.8	12.5	7.2	6.7	3.5	7.1	7.1	13.8	6.7	16.4	8.7	12.5	6.8	8.8	3.5	4.3	2.1	2.2	2.9	5.6	1.7	1.7	1.7	3.8	2.7	1.8	16.1	5.5	3.9	3.5	1.3	0.6	11.7	18.6	24.8	14.1	13.4	9.5	17.7	9.4	12.6	19.6
KMT2D	"ALR, CAGL114, MLL2, MLL4, TNRC21"	ENSG00000167548	"Lysine methyltransferase 2D"	O14686	12	49018975-49059774	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Methyltransferase, Transferase"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"neutrophil: 5.9"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"							HPA035977	Approved		Approved	"Nucleoplasm,Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"	Nucleoplasm	"HPA035977: AB_10670673"	"unprognostic (8.33e-2)"	"unprognostic (1.49e-1)"	"unprognostic (9.14e-2)"	"unprognostic (2.52e-1)"	"unprognostic (8.07e-2)"	"unprognostic (6.91e-3)"	"unprognostic (7.35e-2)"	"unprognostic (2.29e-1)"	"unprognostic (3.57e-1)"	"unprognostic (5.14e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.07e-1)"	"unprognostic (1.68e-2)"	"unprognostic (7.10e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.20e-2)"	"unprognostic (7.60e-2)"	12.1	7.6	4.9	6.7	10.8	26.1	6.8	11.7	10.5	9.5	6.5	5.8	13.0	5.5	15.7	7.4	8.8	8.9	5.8	9.1	6.1	3.5	6.2	6.5	22.9	9.6	6.7	3.3	9.7	11.6	13.3	9.2	12.9	13.7	6.7	6.6	9.8	7.6	8.0	16.1	13.6	9.4	7.1	9.1	13.6	8.3	7.3	5.7	6.2	11.0	6.1	7.6	7.0	6.3	2.0	2.2	5.9	0.5	1.5	0.8	0.6	17.0	16.2	16.4	13.2	17.0	11.4	17.6	9.0	9.4	11.7	6.3	28.4	7.2	17.7	11.7	12.6	11.6	21.6	10.0	9.8	10.3	17.3	22.5	16.9	15.2	11.7	26.7	22.6	9.7	14.3	16.4	17.0	17.4	28.2	9.8	13.2	18.7	13.2	24.9	15.5	14.0	19.9	10.1	6.4	9.8	18.9	13.7	11.6	13.9	13.7	9.5	13.6	23.4	23.1	9.2	16.5	8.1	15.1	14.0	9.0	17.2	10.6	13.8	6.9	0.6	0.5	3.0	0.8	0.2	0.4	0.3	0.3	0.5	0.3	2.0	0.3	0.8	5.9	1.5	0.1	2.2	0.0	0.6	4.9	10.8	11.7	10.5	6.1	3.5	6.7	3.3	13.7	5.7
LEF1	"TCF10, TCF1ALPHA, TCF7L3"	ENSG00000138795	"Lymphoid enhancer binding factor 1"	Q9UJU2	4	108047545-108168956	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation, Wnt signaling pathway"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"lymphoid tissue: 231.5"	"Group enriched"	"Detected in some"	5	"MOLT-4: 103.2;REH: 79.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"naive CD4 T-cell: 42.2"	"Lineage enriched"	"Detected in many"	5	"T-cells: 42.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002087, CAB019405"	Enhanced		Approved	Nucleoplasm				Nucleoplasm		"CAB019405: AB_823558, HPA002087: AB_1079245"	"unprognostic (1.03e-3)"	"unprognostic (7.36e-3)"	"unprognostic (2.97e-2)"	"prognostic favourable (1.37e-5)"	"unprognostic (9.08e-2)"	"unprognostic (5.24e-2)"	"unprognostic (3.81e-2)"	"unprognostic (1.10e-2)"	"unprognostic (1.77e-1)"	"unprognostic (5.21e-2)"	"unprognostic (9.99e-2)"	"unprognostic (1.37e-1)"	"prognostic unfavourable (2.47e-6)"	"unprognostic (1.12e-1)"	"unprognostic (5.22e-2)"	"unprognostic (7.88e-2)"	"unprognostic (8.91e-2)"	0.9	13.5	3.5	9.3	5.4	7.6	2.0	1.6	3.4	3.6	1.0	2.9	0.8	0.4	6.0	3.5	3.4	5.0	2.8	0.5	4.7	5.2	2.7	0.3	2.4	25.3	4.9	1.9	1.8	0.8	0.0	1.1	7.8	3.1	2.8	1.0	1.6	3.1	0.7	0.5	2.4	3.9	2.9	4.4	7.0	0.9	8.2	2.3	231.5	2.7	1.3	20.6	4.8	3.2	0.3	0.1	0.5	0.0	8.9	42.2	9.5	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	1.3	0.3	0.8	4.5	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.6	0.0	3.2	1.2	0.0	0.0	0.0	4.0	0.6	0.0	0.1	0.0	0.1	0.0	2.3	0.0	0.5	0.1	103.2	0.0	0.3	0.2	79.7	1.5	0.0	0.4	0.2	0.5	0.9	0.0	0.0	15.2	0.4	0.0	0.0	2.2	1.8	0.0	2.6	6.7	2.8	18.3	1.3	0.0	8.8	0.0	0.0	0.0	2.6	0.0	0.5	0.1	19.7	8.8	0.0	0.3	42.2	29.2	0.5	8.9	0.0	0.1	25.7	9.5	3.5	5.4	1.6	3.4	4.7	5.2	4.9	1.9	3.1	2.3
LRP1B	"LRP-DIT, LRPDIT"	ENSG00000168702	"LDL receptor related protein 1B"	Q9NZR2	2	140231423-142131701	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Endocytosis	Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 25.7;thyroid gland: 14.9"	"Cell line enhanced"	"Detected in some"		"ASC diff: 4.2;HEK 293: 4.4;HeLa: 2.3;HSkMC: 2.1;U-138 MG: 4.9;U-87 MG: 2.5"	"Cancer enhanced"	"Detected in some"		"glioma: 1.3"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	13	"myeloid DC: 1.4;plasmacytoid DC: 1.2"	"Lineage enriched"	"Detected in single"	14	"dendritic cells: 1.4"	"Low region specificity"	"Detected in all"							"HPA069094, HPA074788"	Approved		Approved	Vesicles			63000	Vesicles		"HPA069094: , HPA074788: "	"unprognostic (5.31e-4)"	"unprognostic (3.68e-2)"	"unprognostic (2.61e-1)"	"unprognostic (7.36e-4)"	"unprognostic (5.19e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.00e-2)"	"unprognostic (3.49e-1)"	"unprognostic (3.75e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.64e-3)"	"unprognostic (1.05e-1)"	"unprognostic (2.94e-3)"	"unprognostic (4.85e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.66e-2)"	"unprognostic (1.36e-1)"	4.8	4.5	17.6	1.3	14.1	1.2	2.6	23.2	25.7	1.4	1.3	6.5	0.0	1.2	1.3	6.8	1.3	1.9	1.4	1.6	18.3	9.3	2.2	1.6	1.4	1.2	10.8	16.7	3.0	1.2	1.1	12.7	1.2	12.8	3.5	1.3	0.1	2.5	3.8	10.5	1.7	1.3	1.3	8.2	1.2	1.5	1.9	10.6	0.0	14.9	0.0	1.3	1.2	1.4	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	4.2	0.0	0.0	0.2	0.9	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.1	0.9	0.2	0.2	0.6	4.4	0.0	2.3	0.0	0.0	0.0	0.0	2.1	0.0	0.0	0.4	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.8	0.2	0.0	0.0	0.0	0.0	0.0	4.9	0.1	0.0	0.0	0.0	0.0	0.0	2.5	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	17.6	14.1	23.2	21.3	18.3	9.3	10.8	16.7	12.8	10.6
LZTR1	"BTBD29, LZTR-1"	ENSG00000099949	"Leucine zipper like transcription regulator 1"	Q8N653	22	20982013-20999038	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067852, HPA068772, HPA071248"	Approved		Approved	Nucleoplasm,Centrosome,Cytosol				Nucleoplasm	"Centrosome, Cytosol"	"HPA067852: , HPA068772: , HPA071248: "	"unprognostic (1.88e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.44e-2)"	"prognostic unfavourable (5.15e-4)"	"unprognostic (9.81e-2)"	"unprognostic (3.55e-1)"	"unprognostic (3.78e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.65e-1)"	"unprognostic (6.25e-2)"	"unprognostic (1.25e-2)"	21.2	16.9	17.3	15.6	17.4	10.3	17.9	20.7	24.7	18.5	18.3	25.3	20.6	18.9	24.9	14.0	16.5	18.3	21.2	15.8	15.4	10.9	17.2	13.1	16.2	12.8	19.6	16.5	21.7	16.2	24.9	26.0	18.8	19.0	16.9	12.9	18.9	17.5	18.0	17.2	15.0	15.7	21.9	14.0	19.3	14.5	10.8	19.2	10.8	19.6	12.6	12.5	18.5	16.4	1.6	2.2	0.2	3.4	1.8	3.0	1.5	6.2	5.1	7.6	9.2	17.6	12.2	6.2	12.8	9.0	7.3	10.0	3.0	2.6	6.6	4.8	14.2	8.4	5.7	10.5	2.9	12.3	13.3	7.1	6.7	4.4	9.4	3.8	9.4	11.2	5.3	9.2	6.7	14.1	29.4	11.5	8.2	3.8	6.8	3.6	2.4	5.6	8.0	11.1	2.6	5.7	8.4	7.5	11.2	6.9	12.1	7.5	5.6	7.1	12.6	17.0	8.7	7.7	6.9	5.0	4.4	2.0	7.7	3.7	8.2	0.0	2.5	0.2	3.0	3.1	1.6	1.6	1.5	2.8	2.2	1.0	2.1	1.5	0.1	1.8	3.4	1.2	0.5	1.5	17.3	17.4	20.7	24.7	15.4	10.9	19.6	16.5	19.0	19.2
MAP2K4	"JNKK1, MEK4, MKK4, PRKMK4, SERK1"	ENSG00000065559	"Mitogen-activated protein kinase kinase 4"	P45985	17	12020824-12143830	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Stress response"	"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 13.2"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB007751, HPA060074"	Enhanced		Approved	"Nucleoplasm,Cell Junctions"				Nucleoplasm	"Cell Junctions"	"CAB007751: , HPA060074: "	"unprognostic (1.55e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.47e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.89e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.93e-3)"	"unprognostic (2.53e-1)"	"unprognostic (2.76e-3)"	"unprognostic (4.82e-2)"	"unprognostic (5.32e-3)"	"unprognostic (3.13e-1)"	"unprognostic (2.30e-1)"	"unprognostic (7.00e-2)"	"unprognostic (1.79e-1)"	10.7	13.2	23.7	9.4	21.0	3.1	14.4	25.0	42.7	12.5	11.5	7.9	8.5	9.6	12.1	17.8	18.5	11.5	10.7	14.9	31.7	29.3	15.8	20.6	11.4	14.6	24.5	27.1	13.0	11.1	19.6	16.7	15.1	23.4	14.5	13.1	6.5	9.8	13.2	20.6	14.4	9.9	13.5	16.3	10.7	10.7	10.3	9.8	10.3	16.5	11.6	13.4	11.1	11.2	2.8	1.8	13.2	4.3	3.5	3.3	2.3	17.9	15.5	20.4	10.5	11.3	14.7	13.0	12.3	16.2	14.0	13.4	9.2	6.2	7.5	10.0	19.1	12.1	17.7	17.1	21.1	13.2	20.8	8.3	9.1	17.3	13.3	7.9	12.6	12.1	17.0	16.4	17.2	12.7	8.8	4.4	17.6	6.7	9.6	7.4	11.9	7.6	11.8	22.9	5.1	19.2	11.6	4.1	12.1	14.2	7.6	11.8	9.6	5.8	11.6	6.9	10.7	9.5	14.5	8.7	9.7	5.9	13.0	6.3	10.0	0.6	2.7	2.0	3.0	1.5	2.7	2.8	2.4	2.4	1.8	2.7	2.0	3.3	13.2	3.5	4.3	1.8	2.6	2.3	23.7	21.0	25.0	42.7	31.7	29.3	24.5	27.1	23.4	9.8
MAP3K1	"MAPKKK1, MEKK, MEKK1"	ENSG00000095015	"Mitogen-activated protein kinase kinase kinase 1"	Q13233	5	56815574-56896152	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"SH-SY5Y: 27.0;THP-1: 25.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Region enriched"	"Detected in many"	6	"olfactory region: 22.5"	"Low region specificity"	"Detected in all"			"CAB004500, HPA046509"	Approved		Approved	Cytosol				Cytosol		"CAB004500: AB_627926, HPA046509: "	"unprognostic (1.77e-1)"	"unprognostic (1.71e-2)"	"unprognostic (4.09e-1)"	"unprognostic (2.18e-1)"	"unprognostic (3.48e-2)"	"unprognostic (5.39e-3)"	"unprognostic (5.20e-3)"	"unprognostic (2.52e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.05e-2)"	"unprognostic (6.73e-2)"	"unprognostic (1.97e-3)"	"unprognostic (2.18e-2)"	"unprognostic (1.58e-1)"	"unprognostic (9.92e-3)"	"unprognostic (1.11e-1)"	6.7	4.9	5.4	14.6	4.8	15.2	14.9	8.0	4.5	7.6	6.7	5.4	7.3	4.3	7.1	9.4	12.7	7.2	5.9	4.3	3.7	3.2	9.5	4.4	8.8	21.4	6.4	3.1	8.4	9.2	6.3	7.9	8.1	4.5	8.3	4.5	12.6	15.4	9.7	3.5	21.8	11.2	4.0	3.8	21.3	5.5	8.5	5.1	11.7	19.2	6.6	18.2	6.0	11.7	6.6	2.8	6.7	7.2	2.7	5.8	2.3	6.4	3.9	6.2	4.1	1.0	0.8	10.4	1.2	1.7	3.9	5.5	18.4	4.9	5.8	0.4	1.5	3.4	5.1	2.3	5.4	2.0	2.2	3.2	1.7	8.6	2.5	5.1	9.0	1.0	2.5	1.2	1.9	1.7	2.8	10.5	1.0	2.8	3.5	6.9	2.8	0.5	5.6	4.4	19.9	6.8	6.8	2.6	27.0	3.8	4.8	11.0	13.2	25.2	4.9	0.3	3.3	1.4	2.3	7.7	3.9	11.1	0.6	3.0	6.6	6.7	4.5	1.0	1.2	6.8	1.2	6.6	3.8	1.8	2.8	5.1	2.5	0.9	2.6	2.7	7.2	1.5	5.8	2.3	5.4	4.8	8.0	4.5	3.7	3.2	6.4	3.1	4.5	5.1
MAX	"bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8"	ENSG00000125952	"MYC associated factor X"	P61244	14	65006174-65102695	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HMC-1: 92.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000328, HPA003474"	Supported		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"				Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB000328: AB_2281783, HPA003474: AB_1079317"	"unprognostic (4.50e-3)"	"unprognostic (1.51e-3)"	"unprognostic (4.08e-2)"	"unprognostic (2.87e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.30e-3)"	"unprognostic (1.53e-2)"	"unprognostic (7.36e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.66e-2)"	"prognostic unfavourable (5.57e-4)"	"unprognostic (2.99e-1)"	"unprognostic (4.68e-2)"	"prognostic favourable (2.12e-4)"	"unprognostic (6.03e-2)"	33.4	25.5	31.3	31.5	38.6	68.7	25.8	59.0	38.2	34.6	29.4	37.2	26.3	31.5	34.3	24.0	47.6	38.2	27.9	30.1	29.9	28.4	26.3	21.8	31.4	43.4	37.1	21.6	39.7	20.0	17.4	23.7	30.2	32.7	31.9	25.0	26.8	33.6	37.7	27.8	32.1	40.2	30.7	34.8	42.9	24.8	15.7	40.9	41.3	30.2	22.5	40.7	35.1	40.7	18.7	19.1	87.5	23.6	19.2	30.0	44.8	28.3	11.1	6.8	11.0	18.0	14.1	8.9	10.0	15.3	12.5	15.4	7.1	19.9	23.6	8.4	12.0	14.1	17.1	13.9	9.4	23.8	10.4	36.7	7.3	7.8	21.1	13.8	92.4	16.8	9.9	11.5	12.7	13.8	17.2	9.6	12.6	15.7	31.9	47.6	9.1	18.2	18.1	10.8	10.6	11.5	9.5	14.7	9.6	13.1	14.0	12.8	13.7	17.7	17.2	11.5	13.9	10.6	8.0	11.8	10.0	14.9	14.3	13.3	11.4	87.5	23.6	80.6	21.7	20.1	23.7	18.7	25.4	22.1	19.1	17.6	26.6	22.3	49.5	19.2	17.4	18.3	30.0	44.8	31.3	38.6	59.0	38.2	29.9	28.4	37.1	21.6	32.7	40.9
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavourable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favourable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"	12.1	20.6	13.2	15.6	17.7	11.8	12.5	25.8	26.9	15.5	14.9	16.4	22.2	16.9	14.8	18.4	18.9	17.6	14.7	9.0	12.4	11.5	15.9	23.0	12.8	22.1	12.5	15.6	19.7	25.9	16.8	18.0	16.1	16.0	15.9	11.6	16.6	23.3	19.9	8.4	21.6	15.8	11.0	9.8	20.6	15.3	21.2	12.3	33.2	23.9	6.2	20.3	13.7	15.5	5.2	2.9	3.4	1.5	1.8	4.8	1.0	16.4	22.1	14.1	22.2	15.8	10.3	16.6	11.8	11.8	18.5	12.4	12.7	16.2	23.4	19.4	9.1	23.5	19.1	16.4	11.1	19.9	28.3	19.4	17.7	17.0	14.0	12.4	13.2	11.8	12.3	15.5	12.9	17.1	28.1	8.9	10.2	30.7	31.4	25.2	18.5	33.2	24.4	16.1	22.4	11.9	15.2	20.0	17.6	14.0	19.8	14.4	29.5	13.9	10.8	17.5	16.8	20.9	10.0	14.1	16.3	11.8	13.8	9.7	11.1	0.9	1.3	3.4	3.7	1.5	4.8	3.7	2.6	4.6	1.3	5.2	4.5	2.6	0.2	1.8	0.5	2.9	1.9	1.0	13.2	17.7	25.8	26.9	12.4	11.5	12.5	15.6	16.0	12.3
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993332-37050918	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: , HPA060714: "	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavourable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"	16.3	20.7	18.2	19.4	21.4	24.4	18.7	19.7	19.6	15.3	17.3	28.8	19.6	12.4	18.7	23.6	15.1	16.2	14.4	32.0	17.3	17.7	18.8	20.5	17.8	22.8	19.9	16.0	17.6	18.1	26.0	29.4	17.3	19.2	18.5	17.7	16.7	15.6	18.1	46.4	14.2	14.1	21.1	21.6	20.7	16.5	27.6	21.5	29.0	22.2	19.5	24.5	16.9	21.4	12.0	12.9	13.2	23.2	6.7	13.4	9.0	14.0	22.2	27.8	0.0	12.4	15.5	12.4	21.0	16.8	24.5	26.1	16.7	15.7	34.9	10.4	17.0	9.7	23.8	17.7	26.2	15.8	12.3	24.4	20.5	23.4	13.7	29.9	17.0	11.5	12.6	22.8	28.4	15.1	31.2	16.7	24.8	11.3	31.1	12.3	20.3	12.2	3.1	33.9	14.7	15.5	15.2	5.9	14.0	21.3	22.6	14.0	32.7	21.3	11.9	19.2	20.8	18.9	24.6	13.2	36.1	32.6	14.9	28.3	17.2	10.9	11.7	13.2	13.4	19.5	9.7	12.0	8.4	10.7	12.9	10.3	9.6	9.7	3.4	6.7	23.2	6.1	12.5	9.0	18.2	21.4	19.7	19.6	17.3	17.7	19.9	16.0	19.2	21.5
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47402969-47663146	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867"	Approved		Supported	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , HPA066845: "	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavourable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavourable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavourable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"	7.3	9.8	14.2	12.2	25.5	11.4	14.1	22.6	18.1	9.4	11.6	7.6	5.6	6.5	10.5	13.3	10.8	11.1	4.9	8.4	13.0	14.0	7.3	5.5	7.1	19.7	12.5	17.0	7.9	8.4	15.3	9.1	9.9	18.5	7.9	13.8	12.3	9.4	7.3	6.7	10.3	8.0	7.8	13.8	9.4	6.7	13.4	13.5	37.0	13.9	6.6	21.4	8.5	7.6	7.4	2.9	3.9	4.2	12.2	12.6	6.2	28.0	9.6	26.3	14.1	1.9	5.5	15.9	16.7	8.3	20.8	20.1	18.0	12.1	34.5	22.6	5.9	11.9	19.6	9.5	31.4	17.8	14.6	24.9	11.1	16.3	2.0	24.3	8.8	3.1	2.8	17.7	4.8	11.4	41.4	8.0	15.8	11.2	28.1	18.3	49.4	11.4	37.7	46.9	20.2	9.0	14.9	21.8	23.6	14.8	11.5	11.8	11.5	9.5	4.6	13.8	18.1	14.2	18.6	5.1	18.3	48.4	8.4	18.0	8.5	2.8	1.0	3.9	7.9	4.2	8.6	6.3	7.4	9.5	2.3	7.4	12.6	11.9	0.7	12.2	3.2	2.9	10.1	6.2	14.2	25.5	22.6	18.1	13.0	14.0	12.5	17.0	18.5	13.5
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810101	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"				Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavourable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavourable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavourable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"	13.0	20.5	9.7	13.1	18.8	13.6	13.0	20.5	13.1	17.9	13.3	17.6	10.7	6.1	28.2	11.0	12.4	18.3	8.4	8.6	11.4	8.8	9.5	14.6	11.0	21.7	23.9	9.6	43.2	27.6	16.2	17.3	14.9	15.0	14.6	10.3	8.7	12.0	13.2	10.4	10.3	10.5	22.1	14.9	11.6	11.1	25.1	22.0	40.4	13.4	10.4	25.8	14.2	16.4	8.4	8.4	7.6	9.8	9.7	15.1	5.7	27.2	20.3	37.9	9.0	11.4	12.1	17.1	15.2	13.4	15.7	16.6	14.9	9.5	45.0	22.7	16.4	11.5	34.1	19.3	20.5	19.6	17.0	28.8	16.2	15.1	7.0	28.9	10.6	9.8	6.2	16.0	10.7	9.8	25.0	16.6	15.3	19.6	30.7	13.7	33.3	9.4	73.0	49.7	20.3	9.6	17.8	21.2	23.0	21.1	10.1	9.2	12.0	10.2	6.0	18.3	22.4	13.8	19.6	15.6	21.0	75.4	15.5	18.5	11.2	7.6	5.8	4.9	8.4	9.8	10.4	8.4	9.5	8.3	8.4	8.1	15.1	7.6	3.9	9.7	9.3	4.2	9.5	5.7	9.7	18.8	20.5	13.1	11.4	8.8	23.9	9.6	15.0	22.0
MTOR	"FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1"	ENSG00000198793	"Mechanistic target of rapamycin kinase"	P42345	1	11106535-11262507	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Biological rhythms"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB069425, HPA071227"	Approved		Approved	Vesicles,Cytosol				"Vesicles, Cytosol"		"CAB069425: , HPA071227: "	"unprognostic (3.18e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.20e-1)"	"unprognostic (2.45e-3)"	"unprognostic (5.50e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.24e-3)"	"unprognostic (3.48e-2)"	"unprognostic (1.88e-1)"	"prognostic favourable (1.49e-5)"	"unprognostic (1.27e-1)"	"unprognostic (2.45e-1)"	"unprognostic (6.60e-2)"	"unprognostic (7.55e-2)"	11.3	13.9	18.7	13.0	22.5	12.3	14.9	25.2	25.2	11.3	14.5	18.2	10.4	11.2	13.8	23.6	13.1	10.5	15.7	14.2	14.5	13.6	15.8	19.4	10.8	14.3	14.0	14.4	10.7	16.6	26.5	16.0	12.5	15.5	15.2	17.1	14.4	14.2	15.2	24.6	16.5	13.6	15.2	10.4	15.4	13.1	38.6	13.1	16.6	13.2	9.9	15.7	11.7	10.2	3.9	4.0	3.0	6.4	2.6	5.6	2.3	15.2	13.8	18.7	14.1	22.6	10.8	9.3	12.9	12.4	17.2	17.0	14.2	14.1	16.9	11.1	15.2	18.2	25.2	19.7	22.3	13.5	18.4	22.5	28.6	17.9	14.2	21.9	16.8	13.8	15.0	24.6	25.0	21.8	25.1	14.6	12.0	17.4	15.1	16.7	14.1	13.1	15.2	22.0	11.3	15.2	13.8	18.9	13.8	27.6	14.9	16.9	12.1	13.0	23.2	15.1	13.7	11.5	17.2	14.4	13.4	33.3	10.9	23.7	15.8	0.7	2.9	3.0	5.2	6.4	4.3	3.9	3.0	2.7	4.0	3.4	3.6	3.1	2.0	2.6	3.3	3.1	5.6	2.3	18.7	22.5	25.2	25.2	14.5	13.6	14.0	14.4	15.5	13.1
NBN	"AT-V1, AT-V2, ATV, NBS, NBS1"	ENSG00000104320	Nibrin	O60934	8	89933336-90003228	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 76.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001429, CAB003836"	Supported		Approved	"Nucleoplasm,Golgi apparatus"				"Golgi apparatus"	Nucleoplasm	"CAB003836: AB_562172, HPA001429: AB_1854460"	"unprognostic (1.52e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.32e-3)"	"unprognostic (7.46e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.05e-2)"	"prognostic unfavourable (5.46e-5)"	"unprognostic (5.05e-2)"	"unprognostic (4.61e-2)"	"prognostic unfavourable (4.20e-4)"	"unprognostic (1.15e-1)"	"unprognostic (6.68e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.28e-1)"	"unprognostic (2.84e-2)"	"unprognostic (1.03e-1)"	19.2	16.1	17.9	23.6	29.5	41.3	23.0	17.4	21.0	19.3	22.6	12.2	16.9	13.3	33.2	16.6	19.7	17.5	20.2	14.2	19.4	16.7	25.9	19.3	17.9	26.7	16.9	18.1	19.3	17.1	21.0	29.4	13.2	18.4	17.6	20.9	7.1	18.4	17.6	15.7	11.2	18.0	22.2	18.1	26.5	14.7	13.9	18.9	23.4	20.8	14.7	22.8	17.5	16.0	10.1	12.0	21.8	18.5	9.7	8.6	7.6	15.1	8.5	8.6	4.5	4.7	11.8	5.5	10.8	14.4	13.8	15.0	4.9	11.5	22.9	12.6	9.8	5.1	10.4	10.1	17.7	10.7	6.0	19.4	5.3	6.9	9.2	11.6	10.3	8.8	5.4	7.7	17.1	11.1	14.2	13.4	15.6	13.5	17.7	7.3	2.5	9.3	11.9	7.5	13.6	17.8	20.9	2.5	7.9	6.8	76.8	6.4	14.4	8.6	8.3	12.0	8.5	7.2	10.6	6.2	7.1	12.8	12.1	10.9	11.0	14.1	11.1	20.3	8.1	12.5	8.6	10.1	5.9	5.9	12.0	6.1	5.7	6.2	21.8	9.7	18.5	6.6	3.7	7.6	17.9	29.5	17.4	21.0	19.4	16.7	16.9	18.1	18.4	18.9
NCOR1	"hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1"	ENSG00000141027	"Nuclear receptor corepressor 1"	O75376	17	16029157-16218185	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA043246, HPA050288, HPA051168, CAB072830"	Supported		Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB072830: , HPA043246: , HPA050288: , HPA051168: "	"unprognostic (1.83e-1)"	"unprognostic (3.05e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.10e-1)"	"unprognostic (7.38e-2)"	"unprognostic (3.59e-2)"	"unprognostic (2.55e-2)"	"unprognostic (4.27e-2)"	"unprognostic (4.87e-2)"	"unprognostic (4.06e-2)"	"unprognostic (7.07e-2)"	"unprognostic (1.52e-2)"	"prognostic favourable (7.92e-5)"	"unprognostic (4.40e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.33e-1)"	"unprognostic (5.42e-2)"	19.6	21.2	25.4	24.0	30.8	27.0	25.0	41.8	31.5	24.0	30.6	19.6	18.6	33.2	29.0	19.5	25.0	20.5	21.9	17.8	22.4	17.8	25.6	33.8	20.1	19.5	25.1	19.1	25.9	24.3	39.9	39.8	19.8	21.6	20.8	29.7	17.1	20.9	29.1	43.0	23.8	36.9	29.7	26.4	23.7	29.8	22.1	26.4	38.8	25.3	15.7	23.8	29.6	27.0	43.4	29.9	78.2	24.8	30.4	35.5	19.7	23.8	39.9	28.5	23.7	23.5	17.9	14.2	17.6	19.9	19.4	17.6	21.3	10.9	25.1	12.4	30.7	18.3	35.0	21.3	28.8	33.4	25.9	25.0	34.5	25.0	23.0	15.6	29.8	18.3	22.4	30.0	35.2	26.9	21.8	10.4	19.0	15.5	27.5	10.1	14.1	10.9	27.5	28.9	11.7	20.1	27.1	9.7	16.2	29.1	12.7	13.8	12.2	17.9	23.4	20.0	11.8	14.6	24.2	7.2	8.3	14.7	19.0	18.6	17.1	78.2	24.8	52.2	31.3	19.5	25.9	40.7	35.5	34.1	17.5	43.4	34.7	34.8	48.5	30.4	24.0	29.9	31.7	19.7	25.4	30.8	41.8	31.5	22.4	17.8	25.1	19.1	21.6	26.4
NCOR2	"CTG26, SMRT, SMRTE, TNRC14, TRAC-1"	ENSG00000196498	"Nuclear receptor corepressor 2"	Q9Y618	12	124324415-124567589	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"basophil: 8.1"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001928	Approved		Supported	Nucleoplasm				Nucleoplasm		"HPA001928: AB_1079454"	"unprognostic (9.51e-3)"	"unprognostic (7.37e-3)"	"unprognostic (4.66e-2)"	"unprognostic (2.55e-3)"	"unprognostic (2.14e-1)"	"unprognostic (7.37e-2)"	"unprognostic (3.19e-2)"	"unprognostic (8.86e-2)"	"unprognostic (2.21e-2)"	"unprognostic (2.90e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.96e-1)"	"unprognostic (9.86e-2)"	"unprognostic (6.26e-2)"	"unprognostic (1.59e-1)"	"unprognostic (7.56e-2)"	"unprognostic (8.90e-2)"	24.0	22.0	21.3	21.3	19.0	16.8	18.3	33.8	33.5	24.5	17.2	24.3	17.7	16.4	21.3	19.0	15.7	16.3	21.5	18.2	22.0	14.8	16.0	11.2	23.4	11.9	19.0	15.6	28.6	30.0	13.8	39.5	13.2	28.3	21.3	7.6	32.7	29.2	24.5	62.4	22.8	22.2	17.4	12.2	17.4	24.0	10.8	22.0	9.3	16.7	25.0	7.6	16.3	14.7	0.6	1.7	8.1	4.0	0.2	1.9	0.4	19.4	36.7	10.5	10.0	6.1	8.3	31.4	20.2	10.1	11.8	5.3	19.5	14.4	19.8	15.0	16.4	18.5	4.1	21.5	4.8	20.8	8.1	15.9	34.6	11.8	12.3	11.9	20.2	13.3	8.1	14.7	8.8	11.2	20.4	5.9	10.5	16.8	42.9	13.8	14.6	35.8	13.9	17.5	10.0	5.6	22.8	27.7	20.2	24.8	21.0	12.7	17.1	15.1	53.9	27.5	47.6	27.1	42.9	11.3	11.4	12.1	15.6	8.9	25.7	8.1	0.7	1.6	1.9	0.4	0.5	0.6	0.5	1.5	0.3	0.4	0.6	0.5	1.6	0.2	4.0	1.7	0.0	0.4	21.3	19.0	33.8	28.4	22.0	14.8	19.0	15.6	28.3	22.0
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	6	"B-cells: 2.3;granulocytes: 6.5;T-cells: 8.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria				Mitochondria		"HPA045502: "	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"	12.9	15.9	22.6	13.3	25.9	5.5	18.5	30.2	26.0	17.6	13.6	19.8	12.2	11.0	16.9	17.0	10.5	15.2	13.1	17.3	21.6	19.6	20.0	15.1	12.7	11.5	19.4	25.6	22.9	16.5	34.1	19.0	19.4	20.9	16.1	14.7	12.1	14.4	20.5	14.8	12.0	12.1	14.5	21.4	11.9	13.0	15.4	21.5	11.6	31.1	7.6	12.4	15.3	19.5	2.3	0.7	6.5	0.4	0.9	8.4	1.0	9.7	12.7	15.5	8.3	13.2	17.2	7.8	8.4	15.3	12.5	14.2	11.4	6.6	9.4	2.4	15.8	17.1	14.0	11.9	21.3	4.5	8.8	8.3	12.0	5.8	9.4	14.8	6.9	13.6	7.6	13.3	16.3	6.0	11.9	9.4	11.9	7.7	12.3	5.4	4.5	4.2	9.7	23.7	7.5	9.5	14.0	6.4	9.6	15.7	5.3	8.7	16.0	9.5	8.8	10.0	14.0	11.8	3.2	8.5	4.1	10.4	8.2	6.3	10.4	6.5	0.4	0.9	2.3	0.2	1.6	2.3	4.4	3.9	0.5	2.1	3.3	3.2	1.0	0.9	0.4	0.7	8.4	1.0	22.6	25.9	30.2	23.5	21.6	19.6	19.4	25.6	20.9	21.5
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"				"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favourable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"	11.8	12.4	23.6	11.1	20.1	10.0	15.4	20.8	28.1	10.8	9.7	9.0	11.8	7.8	10.5	11.3	14.2	11.3	8.0	19.7	26.6	16.4	13.5	11.1	11.9	24.1	18.0	13.5	11.0	12.9	46.8	8.6	6.9	11.4	10.2	8.7	9.5	9.3	15.4	25.7	12.1	8.5	11.9	10.7	10.4	8.8	21.6	10.1	14.9	15.6	11.5	9.9	10.6	10.2	8.5	13.6	6.6	17.3	11.6	15.0	9.8	26.3	10.6	3.7	24.3	7.3	7.3	3.6	21.4	12.1	23.5	20.3	10.5	6.5	7.0	17.8	22.0	9.3	7.7	12.4	21.1	10.2	6.1	8.3	7.9	7.5	7.8	11.9	9.9	6.7	5.7	16.6	20.3	16.5	4.0	6.5	22.8	11.0	7.2	4.7	2.8	10.1	7.5	20.0	6.7	23.8	12.3	5.8	4.0	12.3	8.3	4.8	5.3	4.8	30.6	35.0	39.9	15.2	36.1	10.2	8.1	8.4	9.3	4.7	22.3	6.6	9.5	3.6	15.0	13.5	12.8	8.2	11.3	10.1	13.6	8.5	9.8	9.2	2.3	11.6	17.3	9.3	9.4	9.8	23.6	20.1	20.8	28.1	26.6	16.4	18.0	13.5	11.4	10.1
NOTCH2		ENSG00000134250	"Notch 2"	Q04721	1	119911553-120069626	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Differentiation, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, Receptor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA048743	Approved		Supported	"Nucleoplasm,Plasma membrane"			67000000	"Nucleoplasm, Plasma membrane"		"HPA048743: "	"unprognostic (1.33e-1)"	"unprognostic (1.43e-2)"	"unprognostic (2.66e-1)"	"unprognostic (1.40e-3)"	"unprognostic (7.98e-2)"	"unprognostic (4.01e-2)"	"unprognostic (1.22e-1)"	"unprognostic (7.32e-2)"	"unprognostic (1.18e-2)"	"prognostic unfavourable (5.24e-4)"	"prognostic unfavourable (9.48e-4)"	"unprognostic (3.86e-2)"	"unprognostic (6.12e-3)"	"unprognostic (1.55e-2)"	"unprognostic (2.65e-2)"	"unprognostic (1.12e-2)"	"unprognostic (7.35e-3)"	12.0	7.3	6.0	9.4	6.8	4.4	10.6	3.0	5.6	14.5	7.6	4.4	11.3	1.6	12.3	11.8	13.4	11.4	12.8	7.9	6.8	2.3	5.5	11.4	10.6	5.7	5.3	7.6	15.5	27.6	6.1	3.3	10.3	6.5	9.9	5.2	9.4	17.7	10.0	9.3	17.2	6.1	12.4	6.2	11.5	5.8	15.7	4.4	8.0	11.4	8.6	6.6	9.6	13.0	4.2	5.2	7.7	9.6	1.5	1.7	2.0	14.9	5.0	7.8	6.0	32.7	28.0	7.8	11.4	15.7	15.2	16.5	4.6	4.0	0.3	9.6	21.5	5.7	12.4	10.1	24.3	17.9	7.9	8.6	13.6	0.4	12.2	9.0	2.3	22.4	6.6	45.6	30.4	7.7	0.1	19.0	18.3	16.7	3.8	2.5	10.1	5.6	2.5	27.6	9.6	8.0	9.5	0.3	3.9	15.4	14.5	8.2	8.0	3.1	27.1	19.9	13.7	29.8	17.8	7.9	3.9	4.4	29.2	8.3	18.9	5.6	6.4	6.4	1.5	6.6	1.7	4.2	1.3	1.1	5.2	3.9	1.0	1.7	7.7	1.5	9.6	4.2	0.8	2.0	6.0	6.8	3.0	5.6	6.8	2.3	5.3	7.6	6.5	4.4
PALB2	"FANCN, FLJ21816"	ENSG00000083093	"Partner and localizer of BRCA2"	Q86YC2	16	23603160-23641310	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"CAB014895, HPA057000"	Approved		Supported	Nucleoplasm				Nucleoplasm		"CAB014895: , HPA057000: "	"unprognostic (1.11e-1)"	"unprognostic (5.67e-3)"	"prognostic favourable (2.83e-5)"	"unprognostic (1.43e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.61e-2)"	"unprognostic (2.00e-3)"	"unprognostic (5.18e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.00e-2)"	"prognostic unfavourable (2.35e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.04e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.25e-1)"	"unprognostic (7.20e-2)"	"unprognostic (3.21e-1)"	12.4	9.9	10.7	19.6	11.9	6.8	15.2	16.5	14.1	12.4	14.0	10.8	9.1	14.8	10.9	13.5	17.6	9.6	7.8	10.5	10.0	10.6	13.7	16.1	9.2	13.4	9.7	12.5	15.3	10.6	13.7	16.1	9.1	14.9	10.9	12.7	8.6	11.0	14.7	10.3	17.0	14.1	12.8	10.8	14.1	11.0	16.9	10.5	12.9	12.1	12.0	15.3	13.6	13.3	3.7	3.9	7.2	7.7	3.9	5.5	2.0	11.8	9.2	11.1	7.7	9.2	7.3	9.9	8.6	13.1	14.1	17.1	7.8	12.4	12.5	6.3	6.0	10.6	9.8	14.4	16.9	7.3	5.7	7.6	12.6	21.9	8.6	14.0	12.4	8.2	14.7	13.3	15.2	7.5	15.7	6.7	12.4	11.7	14.4	14.6	24.6	5.3	16.7	13.6	17.1	10.7	10.6	8.2	8.1	8.8	10.0	11.2	9.2	9.6	5.4	16.9	6.5	8.3	9.2	7.9	12.8	12.8	11.1	10.3	10.1	7.2	3.3	3.0	4.4	4.2	5.3	3.7	4.9	5.3	3.9	3.1	5.5	4.3	0.2	3.9	7.7	2.8	3.1	2.0	10.7	11.9	16.5	14.1	10.0	10.6	9.7	12.5	14.9	10.5
PBRM1	"BAF180, PB1"	ENSG00000163939	"Polybromo 1"	Q86U86	3	52545352-52685917	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015629, HPA059373"	Uncertain		Enhanced	Nucleoplasm				Nucleoplasm		"HPA015629: AB_1855012, HPA059373: "	"unprognostic (1.87e-1)"	"unprognostic (1.73e-1)"	"unprognostic (1.91e-2)"	"unprognostic (2.00e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.02e-2)"	"unprognostic (9.54e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.99e-2)"	"unprognostic (4.32e-2)"	"unprognostic (2.89e-3)"	"unprognostic (3.06e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.06e-1)"	24.3	14.8	13.8	20.6	15.9	17.2	24.4	19.1	13.8	18.9	18.5	14.0	22.9	12.2	25.9	13.9	19.9	18.9	13.7	15.9	11.1	10.0	11.7	14.5	14.9	16.5	16.5	8.2	25.1	15.4	14.4	30.6	28.0	14.7	16.1	15.3	12.7	17.5	16.2	21.8	17.2	14.3	21.1	15.6	19.1	14.8	13.1	13.7	51.0	22.0	10.5	17.1	22.4	23.0	6.6	10.7	11.1	8.7	4.6	7.4	1.9	12.3	8.0	28.6	14.0	14.1	14.4	20.0	17.0	11.8	19.7	17.3	8.9	8.4	30.0	2.4	20.0	8.5	24.8	12.9	24.0	32.0	13.3	28.4	15.0	6.9	20.2	23.6	21.6	13.4	14.9	22.0	14.2	19.0	16.2	16.5	19.8	4.1	39.0	7.1	17.3	13.1	20.4	17.9	15.2	8.2	24.2	19.4	21.5	20.5	4.9	16.2	9.2	13.7	21.9	18.5	14.0	15.9	20.8	11.9	18.8	28.5	11.4	19.2	18.4	10.1	5.0	11.1	4.8	3.2	4.9	3.6	4.8	5.3	4.8	6.6	7.4	4.7	2.7	4.6	8.7	10.7	4.5	1.9	13.8	15.9	19.1	13.8	11.1	10.0	16.5	8.2	14.7	13.7
PHF6	"BFLS, BORJ, CENP-31, KIAA1823, MGC14797"	ENSG00000156531	"PHD finger protein 6"	Q8IWS0	X	134373253-134428791	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease mutation, Epilepsy, Hypotrichosis, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001023	Enhanced		Supported	Nucleoplasm,Nucleoli				"Nucleoplasm, Nucleoli"		"HPA001023: AB_1079606"	"unprognostic (2.38e-3)"	"unprognostic (8.21e-2)"	"unprognostic (1.99e-1)"	"unprognostic (3.04e-3)"	"unprognostic (6.03e-3)"	"unprognostic (5.20e-3)"	"prognostic unfavourable (3.38e-4)"	"unprognostic (1.81e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.08e-1)"	"prognostic unfavourable (9.96e-4)"	"unprognostic (1.09e-1)"	"unprognostic (5.96e-2)"	"unprognostic (4.84e-2)"	"unprognostic (7.45e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.29e-2)"	7.4	19.3	10.2	14.1	12.2	6.5	9.7	18.2	13.5	8.7	8.0	11.6	20.3	7.8	9.0	30.1	11.5	7.3	6.1	7.2	11.0	11.1	9.9	7.5	8.4	20.4	12.5	9.3	30.7	10.4	24.1	18.1	8.2	13.3	8.6	9.5	5.4	11.3	16.8	6.2	7.4	10.2	8.1	17.1	17.8	8.1	8.3	14.4	30.2	11.8	6.0	25.0	8.9	9.8	18.4	11.0	5.3	7.4	9.6	9.9	5.0	11.3	9.4	41.3	16.9	7.7	9.9	7.8	11.4	9.1	12.2	15.2	5.6	11.8	18.2	26.2	6.9	10.2	28.8	12.9	20.6	14.8	13.4	17.6	16.1	6.4	8.3	17.5	9.8	6.5	9.8	13.3	16.6	17.0	12.9	9.0	14.9	7.4	28.2	8.7	12.6	12.7	27.9	15.1	13.8	13.0	13.7	14.3	16.9	8.7	8.1	11.9	7.5	9.7	12.9	11.4	8.2	14.3	17.4	4.6	10.7	24.6	7.5	20.9	14.2	5.3	6.1	3.7	7.9	6.0	8.5	18.4	8.2	7.1	8.8	12.8	9.9	8.2	2.5	9.6	7.4	11.0	8.3	5.0	10.2	12.2	18.2	13.5	11.0	11.1	12.5	9.3	13.3	14.4
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5973239-6009125	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA066490, HPA070310"	Approved		Enhanced	Nucleoplasm				Nucleoplasm		"CAB010235: AB_2167281, HPA066490: , HPA070310: "	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favourable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"	6.3	7.4	8.7	6.0	19.8	3.6	8.1	15.5	21.2	6.2	6.0	11.5	6.9	6.4	6.4	6.3	7.5	7.5	5.0	5.3	9.0	10.3	14.2	5.8	5.5	9.1	8.4	9.5	7.5	7.1	16.6	7.1	5.9	16.2	7.0	6.2	8.0	7.1	7.8	5.7	14.8	6.8	7.1	7.5	6.9	6.1	4.8	5.8	7.5	12.4	5.7	10.7	7.7	6.5	6.2	5.8	7.2	7.9	4.0	9.3	6.3	9.5	10.5	8.4	20.9	6.6	9.8	7.2	5.2	3.9	5.0	4.1	9.1	6.9	18.1	6.2	7.4	13.2	12.6	3.3	5.5	7.1	5.1	7.9	8.5	6.5	11.3	9.7	5.4	10.3	9.6	4.0	15.0	9.2	14.7	8.8	8.3	8.8	2.9	6.9	8.5	6.4	9.9	10.1	9.2	10.6	7.2	7.7	16.6	10.1	14.7	11.0	18.2	6.8	7.8	6.4	14.3	9.4	9.3	11.8	19.7	18.2	4.5	9.5	14.6	7.2	5.4	3.1	8.4	7.9	9.3	6.2	6.6	7.2	5.8	5.6	8.8	6.2	2.4	4.0	3.2	5.3	6.4	6.3	8.7	19.8	15.5	21.2	9.0	10.3	8.4	9.5	16.2	5.8
POT1	"DKFZp586D211, hPot1"	ENSG00000128513	"Protection of telomeres 1"	Q9NUX5	7	124822386-124929983	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"											HPA068538			Supported	Nucleoplasm				Nucleoplasm		"HPA068538: "	"unprognostic (1.39e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.04e-1)"	"unprognostic (5.71e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-3)"	"unprognostic (7.88e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (2.48e-2)"	"unprognostic (9.89e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.92e-1)"	"unprognostic (1.75e-2)"	"unprognostic (4.77e-3)"	"unprognostic (7.42e-2)"	12.0	13.2	11.1	8.3	14.3	6.2	15.8	13.0	16.6	13.4	10.1	16.0	12.0	7.8	17.0	13.4	10.1	12.6	11.3	11.2	15.5	11.3	16.6	14.7	9.9	14.0	15.0	12.4	15.7	9.4	15.5	29.6	11.1	16.4	12.0	9.7	12.2	8.7	10.1	9.5	8.0	8.8	13.1	16.4	13.6	9.5	15.8	14.8	17.9	21.5	9.3	12.9	13.6	9.8	4.8	3.6	2.7	3.3	5.2	7.4	2.7	12.7	5.5	8.1	6.2	5.4	10.2	5.7	7.2	8.5	8.2	12.4	4.4	12.9	11.5	5.8	5.4	5.1	8.8	7.3	12.9	14.9	12.9	11.2	5.4	4.7	12.2	10.8	6.7	7.2	8.7	7.5	11.9	10.4	19.9	27.6	9.2	2.5	14.4	11.4	9.1	9.0	8.5	8.5	16.4	7.0	7.1	8.6	11.5	7.3	9.8	10.1	4.3	10.4	3.4	9.9	4.4	11.9	9.5	15.3	15.7	16.4	10.0	12.4	12.2	0.9	3.1	2.7	4.3	3.3	6.3	4.8	4.5	5.0	3.1	3.4	7.4	5.5	0.7	5.2	3.0	3.6	4.4	2.7	11.1	14.3	13.0	16.6	15.5	11.3	15.0	12.4	16.4	14.8
PPM1D	"PP2C-DELTA, Wip1"	ENSG00000170836	"Protein phosphatase, Mg2+/Mn2+ dependent 1D"	O15297	17	60600183-60666280	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MCF7: 26.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA022277	Approved		Approved	"Endoplasmic reticulum"				"Endoplasmic reticulum"		"HPA022277: AB_1858839"	"unprognostic (1.48e-1)"	"unprognostic (1.36e-2)"	"prognostic favourable (3.52e-4)"	"unprognostic (1.76e-1)"	"unprognostic (1.02e-1)"	"unprognostic (5.12e-2)"	"prognostic unfavourable (4.27e-4)"	"unprognostic (5.50e-2)"	"unprognostic (1.70e-2)"	"unprognostic (6.07e-2)"	"unprognostic (2.52e-3)"	"unprognostic (3.46e-2)"	"unprognostic (1.95e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.71e-2)"	"unprognostic (1.98e-1)"	12.2	7.0	6.1	5.7	9.2	13.6	11.9	30.8	6.6	11.1	10.0	10.6	7.8	7.6	12.0	8.3	8.6	11.1	8.3	5.8	7.7	4.4	7.4	7.4	9.2	7.9	10.3	4.6	17.3	12.3	8.1	8.9	18.5	8.8	9.3	9.4	8.2	8.1	6.8	9.7	8.1	8.1	8.2	7.3	9.2	7.3	16.2	12.5	15.5	8.7	6.9	7.0	7.8	11.3	7.3	13.1	20.5	13.2	6.8	8.3	6.8	2.7	5.4	6.1	5.2	4.1	2.5	7.9	4.3	2.8	2.8	4.0	5.5	1.6	7.8	3.5	2.9	2.9	3.9	1.8	3.8	1.4	8.7	5.6	5.4	6.4	3.4	2.2	4.3	2.2	2.9	4.1	2.4	6.3	4.1	3.3	3.0	26.5	6.1	3.4	2.6	4.2	7.4	7.8	4.7	2.5	3.4	8.4	6.1	5.7	1.9	1.3	2.3	3.0	4.6	3.6	10.0	2.8	2.3	5.3	5.6	5.9	1.4	2.3	2.8	8.2	13.2	14.1	6.7	10.2	5.9	7.3	5.6	6.1	13.1	5.9	6.1	6.2	20.5	6.8	6.1	5.8	8.3	6.8	6.1	9.2	30.8	6.6	7.7	4.4	10.3	4.6	8.8	12.5
PPP6C	PP6	ENSG00000119414	"Protein phosphatase 6 catalytic subunit"	O00743	9	125146573-125189939	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity"	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA050940	Uncertain									"HPA050940: "	"unprognostic (6.45e-2)"	"unprognostic (4.01e-3)"	"unprognostic (7.12e-2)"	"unprognostic (5.36e-2)"	"unprognostic (2.78e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.57e-3)"	"unprognostic (1.53e-1)"	"unprognostic (2.14e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.71e-2)"	"unprognostic (2.28e-2)"	"prognostic favourable (4.50e-6)"	"unprognostic (1.54e-2)"	"unprognostic (3.51e-1)"	"unprognostic (1.12e-2)"	"unprognostic (1.12e-1)"	21.7	20.1	20.1	15.7	24.5	24.8	21.2	20.8	26.2	17.0	19.1	25.9	15.1	13.9	15.6	17.2	21.2	14.0	12.9	15.3	19.8	16.6	22.8	17.8	16.3	21.5	20.1	16.1	17.5	27.7	21.3	17.3	17.6	17.8	14.5	21.8	16.8	26.9	14.6	50.5	19.3	17.3	16.3	22.6	19.4	16.5	22.8	23.7	34.1	22.2	20.5	24.0	13.8	15.6	17.3	14.8	32.2	19.5	13.9	23.3	13.8	14.3	10.5	19.2	18.1	20.6	17.3	19.4	15.3	16.6	22.6	18.9	16.8	15.3	20.7	11.9	20.5	29.4	25.9	16.6	26.3	18.5	12.5	17.0	16.5	14.9	16.9	29.6	23.6	14.2	22.8	18.5	17.8	21.0	19.9	24.1	24.3	21.4	27.9	18.7	17.8	19.6	22.8	29.0	27.7	19.2	14.5	19.9	19.7	27.3	22.0	17.7	34.0	18.7	20.4	13.9	13.3	27.0	20.2	26.6	48.0	27.5	18.7	19.4	22.6	27.2	13.2	21.4	14.7	17.4	18.0	17.3	18.9	16.6	14.8	13.3	18.9	17.5	32.2	13.9	19.5	10.7	23.3	13.8	20.1	24.5	20.8	26.2	19.8	16.6	20.1	16.1	17.8	23.7
PRDM1	"BLIMP1, PRDI-BF1"	ENSG00000057657	"PR/SET domain 1"	O75626	6	106086320-106109939	"Cancer-related genes, Predicted intracellular proteins, Transcription factors"	"Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation"	"DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 49.9"	"Cell line enhanced"	"Detected in some"		"Karpas-707: 66.9;RPMI-8226: 12.5;U-266/70: 25.1;U-266/84: 16.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"eosinophil: 5.6;gdT-cell: 12.6;MAIT T-cell: 19.3;memory CD4 T-cell: 12.0;memory CD8 T-cell: 11.6;naive CD8 T-cell: 6.8;neutrophil: 6.8;T-reg: 15.4"	"Group enriched"	"Detected in many"	5	"granulocytes: 6.8;T-cells: 19.3"	"Region enriched"	"Detected in single"	6	"olfactory region: 4.4"	"Low region specificity"	"Detected in all"			HPA030033	Approved		Approved	Nucleoplasm,Nucleoli				Nucleoli	Nucleoplasm	"HPA030033: AB_10601050"	"unprognostic (9.60e-2)"	"unprognostic (3.28e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.98e-2)"	"unprognostic (4.03e-1)"	"unprognostic (3.77e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.81e-1)"	"unprognostic (3.50e-2)"	"unprognostic (7.56e-2)"	"prognostic unfavourable (9.81e-5)"	"unprognostic (1.52e-1)"	"unprognostic (3.51e-1)"	"unprognostic (2.45e-3)"	"unprognostic (7.90e-2)"	11.6	1.5	1.6	26.3	3.2	10.4	7.0	5.3	1.6	14.0	16.5	1.9	1.4	5.4	11.6	2.2	33.4	3.8	8.1	2.3	1.9	2.0	3.1	2.4	18.8	33.3	2.1	0.5	4.2	1.8	1.2	2.1	9.0	4.9	3.6	11.0	4.3	10.6	3.0	2.0	8.9	18.2	3.4	7.4	24.2	8.6	3.0	1.5	3.1	7.7	35.7	49.9	12.8	18.0	1.5	0.2	6.8	0.6	2.5	19.3	1.3	0.4	0.1	0.3	0.0	0.5	0.6	0.0	2.3	7.0	0.7	1.3	0.4	2.7	0.5	0.1	4.5	0.1	0.0	1.0	0.8	6.3	0.0	0.1	1.4	0.0	1.1	0.2	0.5	0.7	3.5	1.0	3.0	0.8	0.4	66.9	0.1	0.0	0.0	0.1	0.2	0.0	0.1	0.0	12.5	0.6	0.1	0.0	0.0	0.3	0.2	0.0	0.3	0.7	0.4	1.1	0.6	0.6	2.1	25.1	16.2	1.4	1.5	0.4	0.6	1.2	0.4	5.6	12.6	0.6	19.3	1.5	12.0	11.6	0.2	0.5	1.1	6.8	6.8	2.5	0.1	0.2	15.4	1.3	1.6	3.2	5.3	1.6	1.9	2.0	2.1	0.5	4.9	1.5
PREX2	"DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129"	ENSG00000046889	"Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2"	Q70Z35	8	67952118-68237030	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"		"Guanine-nucleotide releasing factor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in some"		"AF22: 12.7;HUVEC TERT2: 17.3;NTERA-2: 11.0;RH-30: 5.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015234, HPA075956"	Enhanced		Approved	"Endoplasmic reticulum"				"Endoplasmic reticulum"		"HPA015234: AB_1847604, HPA075956: "	"unprognostic (2.25e-1)"	"unprognostic (3.32e-2)"	"unprognostic (1.30e-2)"	"unprognostic (3.39e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.37e-2)"	"unprognostic (4.19e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.98e-2)"	"unprognostic (2.53e-2)"	"unprognostic (8.77e-2)"	"prognostic unfavourable (1.61e-7)"	"unprognostic (8.30e-3)"	"unprognostic (2.79e-1)"	"unprognostic (3.67e-2)"	"unprognostic (6.64e-2)"	18.8	3.0	14.1	3.3	17.9	1.0	8.5	11.4	16.4	10.8	4.4	13.1	3.0	4.3	6.2	4.5	4.4	12.4	7.6	7.6	15.5	8.1	4.1	3.2	9.1	2.4	12.4	10.0	5.2	3.1	3.7	4.4	17.5	17.2	6.3	4.4	2.6	3.0	5.7	4.9	4.4	4.0	6.1	12.7	3.5	4.1	2.7	16.2	0.0	12.1	3.9	2.9	5.9	15.8	1.1	0.3	0.8	0.1	0.2	0.4	0.0	0.0	0.0	12.7	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	3.3	0.0	0.0	3.6	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	17.3	0.0	0.0	0.0	0.0	2.6	0.0	11.0	0.0	0.0	5.0	0.0	0.6	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.8	0.1	0.1	0.4	0.1	0.2	0.5	0.2	0.2	0.0	1.1	0.2	0.3	0.5	0.2	0.1	0.3	0.0	0.0	14.1	17.9	11.4	13.6	15.5	8.1	12.4	10.0	17.2	16.2
PRKACA	PKACa	ENSG00000072062	"Protein kinase cAMP-activated catalytic subunit alpha"	P17612	19	14091688-14118084	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cushing syndrome, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010361, HPA071185"	Approved		Approved	Cytosol			1300000	Cytosol		"CAB010361: AB_2268772, HPA071185: "	"unprognostic (1.08e-1)"	"prognostic favourable (6.28e-6)"	"unprognostic (2.09e-2)"	"prognostic unfavourable (6.26e-5)"	"unprognostic (1.38e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.64e-1)"	"unprognostic (9.36e-3)"	"unprognostic (7.01e-2)"	"unprognostic (3.41e-1)"	"prognostic favourable (6.47e-4)"	"unprognostic (2.86e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.66e-2)"	"unprognostic (6.14e-3)"	25.6	43.4	19.6	17.8	22.7	9.1	34.1	29.1	39.6	20.6	17.5	16.0	16.2	13.4	19.8	15.6	20.9	18.8	16.4	91.6	20.7	29.4	14.7	34.5	16.5	28.2	21.6	27.5	47.0	15.6	20.8	24.6	15.4	26.9	16.6	16.2	18.4	15.5	24.9	92.4	13.4	14.4	29.0	16.2	28.1	13.9	24.4	11.1	15.2	15.7	26.2	14.8	21.1	17.3	1.7	2.4	8.6	5.3	0.7	1.7	1.2	25.7	15.0	34.0	40.5	30.1	32.0	6.1	27.4	25.4	39.0	35.8	18.2	9.2	11.1	22.2	43.4	16.9	23.9	26.0	37.1	20.3	12.0	20.5	28.3	17.6	25.8	12.6	21.7	30.4	12.5	31.0	10.8	32.8	19.2	29.2	39.8	38.2	28.4	9.5	12.2	33.4	25.7	31.4	25.7	19.0	16.3	26.8	17.1	24.8	15.2	11.3	21.7	12.2	25.4	46.1	12.9	61.6	25.6	20.2	20.7	16.4	30.9	19.2	17.2	0.3	3.4	0.4	1.7	5.3	0.8	1.7	0.9	1.1	2.4	1.3	1.2	1.7	8.6	0.7	4.6	1.6	0.8	1.2	19.6	22.7	29.1	39.6	20.7	29.4	21.6	27.5	26.9	11.1
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol			11000000	Cytosol		"CAB019378: , HPA049979: "	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"	47.1	48.0	41.7	34.5	54.8	14.6	38.7	40.4	57.4	48.2	23.8	44.9	31.4	15.1	43.6	37.7	29.6	43.2	37.4	122.7	42.5	52.3	49.2	43.4	47.3	29.5	50.1	43.6	62.5	19.1	107.8	41.9	47.3	57.7	35.6	24.2	32.2	47.5	43.6	99.8	22.8	19.3	39.4	52.8	35.3	25.1	36.9	40.1	28.2	51.8	23.6	29.2	33.8	33.4	11.3	26.9	52.6	28.7	18.5	13.0	22.9	16.4	31.6	40.6	24.3	54.2	61.6	6.1	22.2	45.8	34.7	30.7	12.3	22.2	16.7	15.3	48.4	13.6	30.0	36.0	49.9	11.3	10.7	25.8	27.5	40.2	39.3	19.7	29.0	44.0	37.4	40.0	33.8	57.6	11.6	26.3	42.0	31.1	21.7	10.6	15.0	21.6	15.2	67.3	18.4	52.6	35.8	14.8	20.0	20.3	37.2	85.5	29.0	27.9	40.8	49.0	23.4	22.1	20.6	21.9	15.5	24.9	29.6	18.8	30.5	31.1	26.1	46.3	13.0	25.5	13.0	11.3	9.8	11.6	26.9	8.5	8.9	9.8	52.6	18.5	28.7	8.8	12.3	22.9	41.7	54.8	40.4	57.4	42.5	52.3	50.1	43.6	57.7	40.1
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease mutation, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 15.5;WM-115: 37.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"gdT-cell: 8.9"	"Lineage enriched"	"Detected in many"	8	"T-cells: 8.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"				"Golgi apparatus"		"CAB013717: , HPA075072: "	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"	4.1	3.8	6.7	6.0	9.5	0.7	7.9	21.0	6.4	28.5	12.5	6.1	8.0	7.8	16.2	4.2	3.0	7.4	13.2	2.8	7.0	6.6	4.9	2.2	7.1	4.5	9.5	3.2	5.2	10.8	3.4	4.0	3.7	6.9	6.9	12.3	11.2	6.9	9.5	2.7	4.3	10.9	8.5	5.1	3.8	12.1	14.3	7.9	1.0	6.3	1.9	3.2	11.3	6.9	1.0	0.0	0.0	0.0	0.3	8.9	1.8	5.0	2.4	10.7	6.7	1.6	2.7	6.1	1.0	0.9	1.2	0.7	2.5	2.5	4.1	1.7	1.9	11.6	6.1	0.8	0.7	4.0	4.0	0.0	2.5	1.1	1.4	0.1	2.2	2.5	1.2	1.1	0.7	2.2	3.6	4.7	0.5	1.0	0.0	1.5	15.5	0.9	0.0	8.2	2.1	0.8	0.7	7.3	3.7	3.6	3.6	1.6	0.9	1.0	0.5	1.4	7.0	7.1	0.7	9.5	8.2	2.7	2.0	2.0	37.0	0.0	0.0	0.0	8.9	0.0	5.3	1.0	1.7	3.8	0.0	0.3	2.8	3.2	0.0	0.3	0.0	0.0	1.4	1.8	6.7	9.5	21.0	6.4	7.0	6.6	9.5	3.2	6.9	7.9
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863113-87971930	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"neutrophil: 29.6"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB004076, HPA031335"	Approved		Supported	Nucleoplasm,Cytosol	"Secreted - unknown location"			Nucleoplasm	Cytosol	"CAB004076: AB_390810, HPA031335: "	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavourable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"	42.4	24.1	17.7	20.9	17.7	13.5	32.8	39.9	19.7	43.1	26.7	9.9	19.0	15.1	29.8	22.8	26.8	30.3	21.0	19.1	16.0	17.4	19.6	32.4	27.2	30.4	15.7	19.5	29.1	21.3	16.4	23.6	36.4	14.2	35.3	17.7	21.6	16.8	20.8	16.8	20.4	25.4	26.0	11.7	40.9	17.8	18.7	12.5	49.7	25.2	13.3	18.6	29.6	30.9	4.3	5.1	29.6	11.0	4.3	4.7	2.0	10.4	4.9	5.7	5.1	13.1	9.0	5.1	5.6	12.5	6.6	9.3	5.0	12.9	12.3	3.8	9.2	6.3	7.5	6.4	10.5	6.2	2.1	4.1	12.8	6.1	14.0	13.8	7.1	6.1	17.9	8.3	10.8	9.3	3.1	33.6	6.0	8.0	7.7	25.1	2.1	0.0	12.0	3.0	9.1	10.3	6.0	2.0	9.2	7.5	3.5	9.4	9.9	20.0	8.1	21.9	5.1	8.5	4.5	11.1	14.3	14.1	6.8	13.1	1.3	8.3	7.9	12.2	3.6	11.0	3.9	4.3	4.0	3.5	5.1	3.7	4.7	4.5	29.6	4.3	7.2	4.2	3.5	2.0	17.7	17.7	39.9	19.7	16.0	17.4	15.7	19.5	14.2	12.5
PTK6	BRK	ENSG00000101213	"Protein tyrosine kinase 6"	Q13882	20	63528001-63537370	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 44.0;intestine: 24.2;skin 1: 24.2"	"Cell line enhanced"	"Detected in some"		"A-431: 11.3;CAPAN-2: 21.8;HaCaT: 17.7;hTCEpi: 24.0;RT4: 13.8;T-47d: 13.3"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB032952, HPA036070, HPA036071"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol"				"Nucleoplasm, Plasma membrane, Cytosol"	"Nuclear bodies"	"CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982"	"unprognostic (2.32e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.42e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.72e-2)"	"prognostic unfavourable (1.96e-4)"	"unprognostic (1.28e-1)"	"prognostic unfavourable (1.26e-9)"	"unprognostic (4.19e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.73e-1)"	"unprognostic (4.24e-2)"	0.7	0.0	0.4	5.3	0.4	0.0	1.7	0.4	0.4	7.6	18.1	0.5	0.8	13.6	0.6	0.5	44.0	0.0	11.7	0.4	0.4	0.0	0.8	1.7	1.1	0.4	0.4	0.4	0.4	1.4	0.0	0.4	0.6	0.4	2.2	7.4	0.4	7.6	0.4	0.4	24.2	24.2	0.9	0.4	0.4	12.5	0.4	0.4	0.4	0.4	18.9	17.2	6.5	15.0	1.3	4.5	1.2	2.4	0.3	1.9	0.9	11.3	1.3	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	21.8	0.0	3.9	0.0	17.7	0.0	0.0	0.0	2.8	0.2	0.0	4.5	0.0	0.0	0.0	3.6	0.0	24.0	0.0	0.1	0.0	0.1	1.3	0.1	6.3	0.0	0.1	0.1	8.2	0.0	0.6	0.2	0.0	13.8	0.2	1.2	1.3	4.3	0.0	13.3	0.8	0.1	0.2	0.2	0.4	0.1	0.2	0.1	0.0	0.2	0.2	0.6	1.2	2.4	0.4	0.5	1.7	1.9	1.2	0.4	0.1	4.5	1.3	0.4	0.6	1.2	0.3	1.3	0.3	0.5	0.9	0.4	0.4	0.4	0.4	0.4	0.0	0.4	0.4	0.4	0.4
PTPN13	"PTP-BAS, PTP-BL, PTP1E, PTPL1"	ENSG00000163629	"Protein tyrosine phosphatase, non-receptor type 13"	Q12923	4	86594315-86815171	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 44.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9"	"Group enriched"	"Detected in many"	7	"monocytes: 4.9;T-cells: 2.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002213, HPA063119"	Approved		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"				Nucleoplasm	"Nucleoli fibrillar center, Cytosol"	"CAB002213: AB_564089, HPA063119: "	"unprognostic (5.36e-2)"	"unprognostic (4.46e-1)"	"unprognostic (1.11e-1)"	"unprognostic (2.54e-3)"	"unprognostic (4.02e-1)"	"unprognostic (9.03e-3)"	"unprognostic (4.43e-2)"	"unprognostic (4.38e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.05e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.28e-3)"	"unprognostic (3.95e-3)"	"unprognostic (2.26e-1)"	"unprognostic (2.66e-1)"	"unprognostic (2.85e-2)"	10.3	5.9	10.8	2.7	16.9	0.7	9.9	5.7	11.6	15.9	4.1	13.0	7.6	1.2	10.8	21.2	18.7	11.4	6.5	5.3	10.4	5.7	22.1	1.6	18.0	4.3	16.9	7.9	24.1	4.3	26.6	38.3	3.0	14.2	12.0	2.4	39.0	5.9	9.4	1.0	43.0	2.3	8.7	10.3	3.5	3.6	12.2	17.6	1.9	16.9	12.4	11.8	15.7	17.6	0.0	0.5	0.1	4.9	0.1	2.3	0.1	5.0	2.5	44.4	4.3	18.8	16.4	0.0	9.3	19.1	3.5	4.5	0.0	2.5	0.0	2.0	10.3	16.7	7.7	14.1	6.9	0.1	5.7	4.2	5.5	0.0	2.3	7.4	0.0	10.5	4.5	2.6	8.6	0.0	0.0	7.2	0.0	2.2	0.6	2.7	10.1	1.9	1.5	0.0	0.0	13.5	21.2	2.6	3.7	2.8	6.2	5.1	3.6	0.2	0.0	3.4	2.7	0.0	1.2	7.6	0.0	0.0	3.6	0.0	1.5	0.0	0.2	0.0	0.2	3.0	2.3	0.0	2.2	0.3	0.5	0.0	0.0	0.0	0.1	0.1	4.9	0.0	0.1	0.1	10.8	16.9	5.7	11.6	10.4	5.7	16.9	7.9	14.2	17.6
PTPRB	PTPB	ENSG00000127329	"Protein tyrosine phosphatase, receptor type B"	P23467	12	70515866-70637440	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Angiogenesis	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"EFO-21: 11.1;HUVEC TERT2: 27.5;TIME: 40.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in single"	7	"memory B-cell: 3.5"	"Lineage enriched"	"Detected in single"	7	"B-cells: 3.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004782, HPA067868"	Uncertain		Approved	"Vesicles,Plasma membrane,Cell Junctions"			6700000	"Plasma membrane"	"Vesicles, Cell Junctions"	"CAB004782: , HPA067868: "	"unprognostic (3.18e-1)"	"unprognostic (2.99e-6)"	"unprognostic (1.56e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.55e-2)"	"unprognostic (1.77e-2)"	"prognostic favourable (6.05e-4)"	"unprognostic (4.59e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.40e-1)"	"prognostic favourable (1.02e-4)"	"unprognostic (2.91e-2)"	"unprognostic (7.18e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.38e-1)"	23.5	7.0	4.5	5.5	7.0	0.1	22.9	3.6	6.1	11.3	8.0	4.3	7.1	5.3	17.1	8.5	5.8	8.2	11.4	17.6	6.2	5.1	18.7	12.0	39.9	3.3	6.9	4.6	5.5	4.4	4.9	5.7	23.3	7.8	6.1	8.2	16.0	3.6	7.1	11.8	4.7	7.4	13.3	7.3	22.9	5.2	3.7	4.3	0.7	14.0	12.2	2.6	6.5	14.7	3.5	0.1	0.2	0.0	0.4	0.3	0.2	1.9	0.1	0.8	0.1	0.0	0.0	0.4	0.4	1.9	1.0	2.4	0.0	1.5	0.7	11.1	0.3	6.8	0.1	0.3	3.5	0.5	0.3	0.1	0.7	0.4	0.1	0.3	0.0	0.0	0.3	2.7	0.0	27.5	1.5	0.4	0.6	0.0	0.0	0.0	1.0	0.4	0.0	0.7	0.3	5.1	0.7	0.0	0.4	0.7	0.0	1.6	0.0	0.6	40.2	0.4	0.4	0.1	2.3	0.5	0.3	0.3	0.2	0.4	0.0	0.2	0.0	0.0	0.2	0.0	0.0	3.5	0.0	0.3	0.0	0.3	0.1	0.0	0.1	0.4	0.0	0.1	0.0	0.2	4.5	7.0	3.6	6.1	6.2	5.1	6.9	4.6	7.8	4.3
PTPRC	"CD45, GP180, LCA, T200"	ENSG00000081237	"Protein tyrosine phosphatase, receptor type C"		1	198638457-198757476	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"				"Group enriched"	"Detected in many"	4	"blood: 116.9;lymphoid tissue: 172.5"	"Cell line enhanced"	"Detected in some"		"Daudi: 51.0;HEL: 28.8;HL-60: 26.0;MOLT-4: 38.5;THP-1: 21.4;U-266/70: 23.9;U-266/84: 21.6;U-698: 30.6;U-937: 23.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000052, HPA000440, CAB002800, CAB056154, CAB068221"	Enhanced		Uncertain	Nucleoplasm,Vesicles	"Intracellular and membrane"			"Nucleoplasm, Vesicles"		"CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: , CAB068221: , HPA000440: AB_1078468"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-2)"	"unprognostic (5.10e-3)"	"unprognostic (2.33e-3)"	"unprognostic (1.30e-1)"	"unprognostic (2.40e-3)"	"unprognostic (1.62e-1)"	"unprognostic (3.17e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.18e-2)"	"unprognostic (8.08e-2)"	"unprognostic (3.95e-1)"	"prognostic unfavourable (2.42e-4)"	"unprognostic (2.31e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.41e-2)"	"unprognostic (7.06e-2)"	9.8	2.9	3.4	48.0	6.2	36.1	4.3	1.3	3.5	3.1	5.6	2.8	0.5	4.9	2.9	3.9	4.8	5.6	8.8	4.9	3.9	4.5	4.4	5.2	27.5	93.2	7.9	1.3	2.9	2.1	0.3	2.5	4.5	5.3	4.2	5.8	3.3	10.7	1.0	1.7	2.5	22.2	4.5	13.2	89.3	6.5	2.3	5.3	172.5	4.6	3.9	53.2	13.1	3.7	28.5	42.8	94.7	103.8	53.7	76.1	116.9	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	51.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	28.8	0.0	0.0	0.0	26.0	0.1	0.0	0.0	0.0	0.0	0.1	0.6	0.8	0.0	0.0	38.5	15.7	0.1	0.1	1.1	0.1	0.1	0.0	0.0	0.3	0.4	0.0	0.1	0.1	0.0	21.4	0.3	0.0	0.2	0.1	0.1	23.9	21.6	30.6	0.0	23.3	0.1	20.8	52.0	56.3	76.1	99.7	64.5	28.5	52.9	72.7	42.8	26.8	60.2	60.3	94.7	53.7	103.8	6.4	54.6	116.9	3.4	6.2	1.3	3.5	3.9	4.5	7.9	1.3	5.3	5.3
PTPRT	"KIAA0283, RPTPrho"	ENSG00000196090	"Protein tyrosine phosphatase, receptor type T"	O14522	20	42072752-43189970	"Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Hydrolase, Protein phosphatase, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"brain: 23.5;fallopian tube: 17.0"	"Cell line enhanced"	"Detected in some"		"BEWO: 4.5;RPMI-8226: 1.2;SCLC-21H: 2.9;U-266/70: 1.0"	"Cancer enhanced"	"Detected in many"		"breast cancer: 5.1"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017336, CAB069423"	Approved									"CAB069423: AB_1622602, HPA017336: AB_1855943"	"unprognostic (7.17e-3)"	"unprognostic (1.02e-1)"	"unprognostic (5.61e-3)"	"unprognostic (1.08e-2)"	"unprognostic (5.95e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.31e-2)"	"unprognostic (6.93e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.37e-6)"	"unprognostic (3.16e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.17e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.17e-1)"	0.6	0.8	5.0	0.6	11.1	0.5	4.6	1.6	23.5	1.6	0.7	0.9	0.0	1.2	0.5	1.8	0.5	17.0	0.7	0.8	4.7	6.5	0.6	0.9	2.1	1.0	2.2	12.6	0.5	0.9	0.5	4.1	4.6	5.1	0.8	0.6	0.5	2.0	4.6	0.5	0.8	1.0	0.5	1.4	0.7	1.8	2.8	0.9	4.9	0.5	0.0	1.1	0.5	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.5	0.0	0.4	0.0	0.0	0.3	0.0	0.0	0.0	1.2	0.0	0.0	2.9	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	11.1	1.6	22.6	4.7	6.5	2.2	12.6	5.1	0.9
RAD21	"hHR21, KIAA0078, SCC1"	ENSG00000164754	"RAD21 cohesin complex component"	O60216	8	116845935-116874866	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Activator, Developmental protein, Repressor"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA020044, CAB022065"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB022065: , HPA020044: AB_1856035"	"unprognostic (7.85e-2)"	"unprognostic (4.92e-1)"	"unprognostic (3.05e-1)"	"unprognostic (5.43e-3)"	"unprognostic (9.56e-2)"	"unprognostic (3.50e-1)"	"prognostic unfavourable (1.71e-4)"	"unprognostic (1.86e-3)"	"unprognostic (8.99e-2)"	"unprognostic (8.80e-2)"	"unprognostic (5.58e-3)"	"unprognostic (3.56e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.95e-1)"	31.6	40.9	48.2	30.5	52.2	78.5	37.7	58.8	55.3	24.2	36.3	37.5	21.5	24.8	30.5	25.3	32.1	23.1	22.0	37.8	45.6	44.1	30.5	27.9	29.6	49.2	54.3	35.4	33.5	18.2	29.1	30.0	38.9	45.5	26.5	37.3	19.0	25.3	31.0	37.8	24.0	26.0	33.4	49.7	31.2	31.5	37.6	56.2	58.3	41.9	20.9	50.4	37.1	36.0	8.7	5.4	17.9	7.1	8.0	25.4	6.2	42.6	21.0	41.1	23.1	20.7	17.9	18.4	29.7	28.2	33.0	30.5	17.2	40.3	63.1	16.4	21.1	23.8	35.0	19.1	38.7	83.7	22.5	64.3	25.8	21.9	13.0	20.6	37.9	15.2	15.7	19.3	23.4	25.8	25.8	88.4	28.4	25.7	94.3	12.1	24.1	26.5	34.6	29.9	31.7	19.6	25.1	52.0	26.8	31.1	84.0	20.0	35.2	25.5	18.8	23.3	34.2	24.4	31.1	46.8	53.8	56.8	19.9	29.7	27.9	17.2	4.5	15.5	11.0	5.3	11.2	8.7	12.9	13.0	5.4	8.3	13.5	13.0	17.9	8.0	7.1	4.5	25.4	6.2	48.2	52.2	58.8	55.3	45.6	44.1	54.3	35.4	45.5	56.2
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303726-48599436	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MOLT-4: 57.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: "	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavourable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"	19.6	21.5	14.9	23.2	18.4	14.7	28.1	25.6	19.4	18.0	13.2	11.5	19.0	12.3	16.8	19.5	27.9	12.7	15.3	19.5	15.4	15.3	18.1	12.1	25.4	30.1	17.0	11.8	15.2	11.6	12.8	17.2	21.5	16.0	15.5	15.3	11.6	20.0	17.4	27.9	20.3	14.3	16.8	23.6	29.4	13.7	14.4	15.3	39.1	19.9	15.8	25.3	17.4	23.6	20.5	10.3	13.2	12.2	3.6	4.6	4.0	9.0	4.9	13.4	14.4	6.6	7.7	6.1	17.9	14.9	18.9	16.1	4.2	16.1	11.7	4.1	11.9	12.6	17.4	14.4	28.9	16.4	6.6	21.6	10.1	7.1	7.1	18.5	20.5	4.3	8.9	12.2	15.7	13.0	7.1	9.7	21.6	4.3	57.9	9.3	6.5	5.4	24.9	13.4	13.5	19.6	8.8	0.6	13.7	17.7	8.9	14.6	9.7	24.2	10.1	11.7	7.7	14.3	16.1	4.3	1.2	0.1	6.2	11.6	15.8	11.0	9.7	5.0	4.6	12.2	3.7	17.4	3.8	4.6	9.3	20.5	3.2	3.8	13.2	3.6	12.1	10.3	4.5	4.0	14.9	18.4	25.6	19.4	15.4	15.3	17.0	11.8	16.0	15.3
RBM10	"DXS8237E, GPATC9, GPATCH9, KIAA0122, ZRANB5"	ENSG00000182872	"RNA binding motif protein 10"	P98175	X	47144869-47186813	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034972, HPA057372"	Approved		Enhanced	"Nuclear speckles"				"Nuclear speckles"		"HPA034972: AB_10602919, HPA057372: "	"unprognostic (9.07e-2)"	"prognostic favourable (6.71e-4)"	"unprognostic (7.83e-2)"	"unprognostic (1.61e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.04e-2)"	"unprognostic (4.47e-3)"	"unprognostic (8.11e-2)"	"unprognostic (9.86e-3)"	"unprognostic (1.76e-1)"	"prognostic favourable (2.86e-6)"	"unprognostic (1.18e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.33e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.40e-2)"	"unprognostic (1.20e-3)"	18.1	22.2	19.8	38.0	21.9	34.0	17.1	41.2	22.9	19.9	20.5	25.7	22.7	21.8	22.1	17.3	23.7	26.2	29.1	21.7	19.8	18.3	18.4	21.6	17.1	27.2	20.1	19.2	36.4	27.4	20.1	28.3	24.9	17.9	23.5	14.2	18.5	25.1	28.8	20.6	23.8	23.7	18.9	17.2	24.7	20.5	8.7	21.4	32.9	26.8	18.0	22.7	17.6	20.9	15.9	14.6	14.4	19.2	12.3	18.3	11.5	20.7	22.5	21.6	25.5	11.6	9.5	25.1	15.8	9.3	16.4	16.0	19.6	17.1	25.4	9.7	10.9	20.3	28.1	19.9	9.0	25.7	25.5	19.0	27.4	20.5	16.9	19.1	22.9	12.5	9.6	27.0	22.0	17.5	15.8	20.4	9.9	31.7	35.0	32.4	35.6	25.3	31.0	18.0	26.2	12.1	18.4	25.6	19.5	23.9	17.9	15.2	22.0	19.1	15.3	19.3	24.5	20.8	16.6	21.5	17.4	20.9	17.1	13.8	26.9	14.0	10.8	14.4	18.3	14.5	17.0	15.9	14.7	15.3	12.3	15.6	14.8	14.1	10.1	12.3	19.2	14.6	16.6	11.5	19.8	21.9	41.2	21.9	19.8	18.3	20.1	19.2	17.9	21.4
RECQL4	RecQ4	ENSG00000160957	"RecQ like helicase 4"		8	144511288-144517845	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"				"Tissue enhanced"	"Detected in many"		"bone marrow: 21.0;lymphoid tissue: 18.9"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in some"			"Group enriched"	"Detected in many"	14	"B-cells: 1.9;monocytes: 1.0;T-cells: 1.6"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"CAB017800, HPA025821"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"CAB017800: , HPA025821: AB_1856168"	"unprognostic (5.92e-2)"	"unprognostic (1.86e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.17e-2)"	"unprognostic (3.17e-2)"	"prognostic unfavourable (1.91e-4)"	"unprognostic (1.12e-2)"	"unprognostic (4.12e-2)"	"unprognostic (7.53e-2)"	"unprognostic (2.65e-2)"	"unprognostic (4.26e-2)"	"unprognostic (1.12e-3)"	"unprognostic (8.82e-3)"	"unprognostic (1.74e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.34e-1)"	2.0	1.6	2.6	12.3	5.6	21.0	2.8	11.5	3.7	1.8	4.3	1.5	1.6	5.6	2.5	4.9	9.4	1.5	1.9	1.9	2.3	1.7	1.6	1.9	1.6	5.9	1.5	2.2	1.9	3.5	0.3	2.4	2.7	2.2	7.7	1.5	1.4	5.4	0.9	2.1	9.4	4.8	1.1	1.7	4.7	3.0	18.1	1.8	18.9	2.5	5.3	8.0	1.6	1.8	1.9	0.1	0.0	1.0	0.0	1.6	0.2	10.3	18.5	8.7	18.2	0.5	0.8	15.2	10.5	1.9	7.8	6.6	18.2	15.3	7.1	7.0	1.7	12.6	5.7	4.5	2.1	12.4	21.8	25.5	31.7	13.5	0.1	6.4	21.2	1.1	0.6	8.7	1.7	2.1	25.3	9.2	2.6	32.0	23.5	17.5	6.0	22.2	24.6	6.8	11.8	2.1	11.2	17.1	10.3	14.2	11.9	3.7	14.5	14.2	2.9	12.6	38.3	15.1	19.3	5.1	5.4	11.9	7.3	20.0	12.6	0.0	0.1	0.0	1.1	1.0	0.0	1.9	0.5	1.1	0.1	0.0	0.9	1.6	0.0	0.0	0.0	0.1	0.0	0.2	2.6	5.6	11.5	3.7	2.3	1.7	1.5	2.2	2.2	1.8
RET	"CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51"	ENSG00000165731	"Ret proto-oncogene"	P07949	10	43077027-43130351	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 63.9"	"Cell line enhanced"	"Detected in some"		"MCF7: 17.6;NB-4: 11.6;SH-SY5Y: 89.7;THP-1: 26.8"	"Cancer enhanced"	"Detected in many"		"breast cancer: 11.0"	"Low region specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"non-classical monocyte: 6.7"	"Group enriched"	"Detected in many"	13	"dendritic cells: 2.1;monocytes: 6.7"	"Low region specificity"	"Detected in many"			"Region enriched"	"Detected in many"	6	"midbrain: 95.5"	"CAB002581, HPA008356, HPA008495"	Approved	Supported	Approved	"Golgi apparatus,Plasma membrane,Cytosol"			260000	"Golgi apparatus, Cytosol"	"Plasma membrane"	"CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: "	"unprognostic (7.94e-2)"	"unprognostic (3.68e-2)"	"unprognostic (4.49e-1)"	"prognostic unfavourable (5.02e-4)"	"unprognostic (1.15e-1)"	"unprognostic (9.13e-4)"	"unprognostic (1.27e-2)"	"unprognostic (3.62e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.54e-3)"	"unprognostic (4.43e-1)"	"unprognostic (9.35e-5)"	"unprognostic (1.64e-3)"	"unprognostic (8.28e-2)"	"unprognostic (3.67e-3)"	"unprognostic (2.02e-2)"	1.8	15.2	1.1	1.8	1.3	0.7	1.2	4.1	9.0	1.9	3.1	0.9	1.1	1.5	0.9	0.6	1.2	0.7	1.0	1.2	1.5	5.8	1.0	11.7	0.7	0.8	17.5	1.2	0.8	1.3	63.9	6.3	0.8	16.8	2.2	1.5	2.8	13.6	2.0	4.5	1.1	2.6	1.1	2.8	0.6	2.1	2.0	0.0	0.1	0.8	5.1	0.6	1.9	1.4	0.2	2.1	0.0	6.7	0.0	0.3	0.4	0.0	0.1	0.0	0.5	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	17.6	0.0	11.6	2.1	0.0	0.0	0.0	0.0	0.0	0.0	1.3	89.7	0.0	0.0	0.0	1.2	26.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.8	0.0	0.2	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	6.7	2.1	0.3	0.4	1.1	1.3	4.1	9.0	1.5	5.8	17.5	1.2	16.8	0.0
RNF43	"DKFZp781H0392, FLJ20315, URCC"	ENSG00000108375	"Ring finger protein 43"	Q68DV7	17	58352500-58417595	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"	"Ubl conjugation pathway, Wnt signaling pathway"	"Developmental protein, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"CACO-2: 14.9;Hep G2: 29.2"	"Cancer enhanced"	"Detected in many"		"colorectal cancer: 41.7"	"Region enriched"	"Detected in many"	7	"cerebellum: 30.6"	"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA008079	Uncertain									"HPA008079: AB_1856371"	"unprognostic (2.53e-1)"	"unprognostic (1.09e-1)"	"unprognostic (7.46e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.33e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.62e-1)"	"unprognostic (2.93e-1)"	"unprognostic (1.05e-1)"	"unprognostic (5.69e-2)"	"unprognostic (3.79e-1)"	"prognostic favourable (6.04e-9)"	"unprognostic (3.61e-3)"	"unprognostic (2.56e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.04e-2)"	0.4	9.4	2.2	6.2	3.5	1.9	4.5	30.6	4.3	3.4	26.4	0.9	21.3	18.5	1.7	9.1	10.0	3.9	8.1	3.3	1.9	1.3	8.0	7.0	6.1	2.7	0.8	1.1	1.6	13.2	3.0	13.3	8.7	4.1	8.0	16.3	3.8	13.7	19.0	0.5	8.9	29.0	0.9	0.8	0.9	4.9	3.1	0.7	3.0	1.8	5.7	6.6	4.0	4.4	0.9	1.1	1.7	1.8	5.6	3.6	1.2	0.7	10.4	1.9	0.0	0.0	0.0	5.8	0.0	0.0	0.0	0.0	14.9	5.0	4.2	5.3	0.0	2.9	0.4	4.0	0.0	8.8	7.3	3.4	0.5	29.2	0.0	4.2	3.0	0.0	8.2	0.0	1.3	0.0	0.3	3.6	0.0	0.1	2.2	3.9	0.3	0.7	6.9	0.0	2.2	3.7	5.6	1.2	0.3	0.9	0.4	0.3	1.3	1.2	0.0	0.1	1.2	0.0	0.0	3.8	1.7	3.3	0.4	0.4	2.4	1.7	0.2	1.6	3.1	0.8	3.2	0.9	2.5	3.6	0.4	0.9	2.3	3.0	0.8	5.6	1.8	1.1	1.2	1.2	2.2	3.5	30.6	4.3	1.9	1.3	0.8	1.1	4.1	0.7
RPL5	"L5, PPP1R135"	ENSG00000122406	"Ribosomal protein L5"	P46777	1	92831983-92841924	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins"		"Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding"	"Cancer-related genes, Diamond-Blackfan anemia, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"HPA043717, HPA054444"	Approved		Supported	"Nucleoli,Endoplasmic reticulum,Cytosol"			130000	"Endoplasmic reticulum, Cytosol"	Nucleoli	"HPA043717: AB_10964719, HPA054444: "	"unprognostic (5.81e-3)"	"unprognostic (3.96e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.52e-1)"	"unprognostic (9.44e-3)"	"unprognostic (1.96e-1)"	"unprognostic (1.03e-3)"	"unprognostic (9.95e-2)"	"unprognostic (8.68e-2)"	"unprognostic (1.23e-1)"	"unprognostic (3.98e-2)"	"unprognostic (3.48e-1)"	"prognostic unfavourable (6.81e-5)"	"unprognostic (2.26e-2)"	"unprognostic (3.12e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.97e-1)"	119.4	80.3	50.0	70.0	50.1	113.8	140.5	46.9	46.8	158.6	111.4	45.0	75.1	61.7	135.2	114.6	159.4	100.5	73.1	73.0	43.5	43.1	99.7	114.9	89.9	148.2	54.5	36.2	296.8	306.5	40.8	90.3	90.2	44.3	175.4	78.8	64.3	121.5	73.2	109.1	97.8	95.3	153.4	61.9	130.1	90.0	68.8	45.7	156.6	210.0	97.7	118.9	191.2	146.6	104.5	85.2	12.8	45.9	72.4	143.0	142.1	116.8	50.2	89.5	75.5	116.4	235.3	143.6	69.9	93.6	87.1	62.4	133.0	51.1	220.5	112.3	78.5	74.7	102.6	131.0	111.3	69.8	140.4	114.4	83.6	122.4	139.7	175.1	48.2	192.4	206.7	77.3	170.2	120.2	141.6	116.3	99.7	66.3	139.4	198.6	138.2	94.9	128.1	173.4	142.4	105.6	97.3	76.3	91.3	45.5	127.1	203.3	70.0	240.9	73.0	44.0	80.4	83.1	126.0	72.0	68.3	149.2	29.8	151.0	29.8	12.8	45.9	7.2	60.9	44.8	122.1	104.5	111.5	91.6	85.2	88.4	143.0	123.9	4.4	72.4	38.3	71.1	83.2	142.1	50.0	50.1	46.9	46.8	43.5	43.1	54.5	36.2	44.3	45.7
SBDS	"CGI-97, FLJ10917, SDS, SWDS"	ENSG00000126524	"SBDS, ribosome maturation factor"	Q9Y3A5	7	66987677-66995601	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ribosome biogenesis"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028891	Approved		Supported	Nucleoplasm,Cytosol			55000	"Nucleoplasm, Cytosol"		"HPA028891: AB_10601500"	"prognostic unfavourable (1.49e-4)"	"unprognostic (1.87e-2)"	"unprognostic (5.73e-2)"	"unprognostic (1.71e-3)"	"unprognostic (8.06e-3)"	"prognostic unfavourable (3.65e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.44e-1)"	"unprognostic (6.99e-2)"	"unprognostic (7.84e-3)"	"unprognostic (4.59e-1)"	"unprognostic (1.04e-2)"	"unprognostic (9.38e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.30e-1)"	"unprognostic (5.06e-3)"	40.9	34.5	37.7	18.7	44.0	41.7	44.5	23.6	43.2	30.7	37.5	35.3	20.2	39.1	35.6	27.3	40.8	27.7	34.0	70.0	39.2	40.9	36.9	38.4	32.1	16.7	50.6	36.6	31.9	27.5	50.4	26.9	38.6	44.6	35.1	35.7	20.1	23.5	40.5	130.7	26.1	34.4	52.0	63.2	16.7	32.8	15.9	48.2	7.2	33.9	38.7	15.6	54.0	38.0	21.6	15.5	20.8	12.6	16.6	39.1	19.4	31.0	13.2	11.7	10.6	42.7	31.9	13.1	52.9	43.6	40.5	31.2	27.1	16.0	11.5	40.2	48.3	15.1	19.7	31.4	43.6	11.0	26.0	5.7	24.6	16.2	38.0	14.4	7.9	28.8	42.3	30.8	53.6	24.9	41.7	12.6	62.9	18.6	7.6	21.0	13.0	31.4	5.8	25.2	24.2	42.7	13.9	18.0	12.4	26.5	45.9	35.1	34.2	12.2	33.1	54.8	18.7	27.7	38.5	7.8	9.2	26.4	18.8	23.7	30.3	20.8	11.1	20.2	23.4	12.6	29.6	21.6	30.6	27.2	11.3	18.7	39.1	31.5	4.7	16.6	11.2	15.5	25.9	19.4	37.7	44.0	23.6	43.2	39.2	40.9	50.6	36.6	44.6	48.2
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-256700	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease mutation, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 100.1;skeletal muscle: 114.0"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria			780000	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavourable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favourable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"	17.6	31.4	15.3	11.5	20.3	10.6	12.8	18.8	29.0	10.2	29.4	17.3	10.0	44.3	11.3	12.1	15.3	12.6	14.8	100.1	15.8	14.5	36.5	55.4	10.7	11.7	19.6	19.3	14.5	14.7	23.2	9.5	9.2	29.7	10.7	24.6	14.5	17.3	12.0	114.0	11.5	39.9	16.5	13.2	13.9	21.2	14.6	14.8	15.7	12.5	39.6	12.5	13.2	11.1	28.3	31.9	29.1	29.2	27.1	48.9	32.4	18.4	29.9	12.3	20.1	21.2	15.9	33.4	14.2	18.1	24.5	25.0	32.4	25.1	22.8	45.0	16.2	23.9	21.7	29.0	14.5	48.6	19.9	11.6	82.6	42.0	13.1	14.4	15.1	15.8	18.7	18.3	9.7	26.5	18.6	19.0	11.5	28.2	19.1	39.0	4.2	37.9	24.7	17.9	44.2	52.2	24.5	13.6	7.8	67.0	43.3	17.6	26.3	18.3	19.2	18.2	17.9	10.8	11.7	20.2	8.6	16.8	17.6	20.9	11.5	17.8	24.4	29.1	36.4	29.2	32.1	28.3	34.8	35.1	31.9	24.5	34.5	31.7	5.9	27.1	24.1	20.5	48.9	32.4	15.3	20.3	18.8	29.0	15.8	14.5	19.6	19.3	29.7	14.8
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054170	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"			Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: , CAB068234: , CAB068235: , HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favourable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"	17.8	25.6	19.8	16.6	21.7	17.0	26.4	18.0	29.1	13.9	30.8	12.3	15.1	34.0	14.2	15.7	19.8	13.6	15.1	86.9	18.2	16.4	51.0	75.1	16.8	24.6	20.1	18.9	10.5	30.7	20.0	11.3	15.6	16.7	13.0	31.5	11.7	15.9	19.5	96.2	13.2	31.4	21.3	16.5	17.2	21.7	18.7	15.7	14.2	15.5	52.2	18.0	15.4	17.1	22.2	45.9	48.5	48.7	18.9	26.7	25.0	25.5	25.4	14.5	18.5	28.2	28.1	16.5	22.4	28.8	51.4	46.5	35.7	30.8	35.1	28.0	30.2	30.2	57.7	44.7	58.0	20.6	47.3	31.6	26.4	27.4	34.6	49.4	23.6	28.8	29.5	44.4	75.3	36.3	26.4	40.7	35.7	21.1	32.8	28.2	12.0	51.1	23.6	27.9	43.5	47.3	14.5	27.3	15.0	30.4	38.1	63.9	22.3	27.9	18.0	19.8	22.3	36.3	29.5	17.0	20.9	35.9	30.3	75.3	21.8	16.6	38.4	37.4	18.3	48.7	18.3	22.2	21.2	19.5	45.9	18.3	19.3	19.5	48.5	18.9	42.2	21.5	26.7	25.0	19.8	21.7	18.0	29.1	18.2	16.4	20.1	18.9	16.7	15.7
SDHC	"CYB560, cybL, PGL3"	ENSG00000143252	"Succinate dehydrogenase complex subunit C"	Q99643	1	161314257-161375340	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"																		"unprognostic (1.48e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.02e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.33e-1)"	"unprognostic (7.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-2)"	"unprognostic (1.29e-1)"	"prognostic favourable (2.20e-4)"	"unprognostic (9.14e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.19e-3)"	"unprognostic (3.77e-1)"	36.8	49.7	25.6	17.1	27.3	14.1	24.1	14.4	36.2	20.6	29.1	31.2	17.0	34.3	22.1	19.7	35.2	21.4	19.3	35.5	21.5	21.8	65.9	75.3	17.8	20.9	28.6	20.1	20.1	17.2	28.8	17.0	19.2	28.0	20.8	28.4	23.9	28.5	21.9	98.0	21.6	33.4	23.2	24.9	21.2	24.3	17.0	16.2	25.7	35.9	45.4	22.4	20.6	19.2	31.3	60.4	28.3	48.2	29.0	38.6	47.9	30.0	22.0	31.0	26.7	40.9	32.8	34.3	33.3	26.6	25.9	20.0	32.5	37.4	8.9	43.4	33.6	35.2	41.4	35.0	30.0	31.9	40.6	20.6	21.0	33.4	23.3	38.2	22.2	34.5	28.9	30.1	20.3	26.9	29.0	8.4	41.7	28.9	27.1	22.1	30.5	23.3	28.5	30.3	37.9	54.6	29.9	21.7	36.9	40.1	75.6	47.7	61.7	48.0	23.7	18.0	27.6	25.4	28.8	44.0	53.7	52.9	26.3	25.0	34.8	27.7	48.2	28.3	36.0	44.9	38.6	31.3	32.3	35.5	60.4	30.6	36.3	35.7	23.9	29.0	38.8	44.8	35.2	47.9	25.6	27.3	14.4	36.2	21.5	21.8	28.6	20.1	28.0	16.2
SDHD	"cybS, PGL, PGL1"	ENSG00000204370	"Succinate dehydrogenase complex subunit D"	O14521	11	112086773-112120013	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes, Disease mutation, FDA approved drug targets, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											HPA045727	Approved				"Intracellular and membrane"					"HPA045727: AB_10963114"	"unprognostic (9.13e-2)"	"unprognostic (3.51e-2)"	"unprognostic (4.47e-3)"	"unprognostic (4.21e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.98e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.83e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.80e-1)"	"prognostic favourable (1.99e-10)"	"unprognostic (5.14e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.56e-2)"	"unprognostic (7.51e-2)"	20.9	23.1	17.1	21.7	19.4	10.9	19.6	14.1	18.4	18.1	33.6	14.2	23.9	36.0	22.7	17.5	35.2	17.3	17.9	42.5	15.1	13.7	66.6	75.4	19.1	23.3	17.1	15.1	18.6	23.2	22.5	16.1	20.1	18.0	23.7	33.9	15.7	32.6	21.7	65.4	15.5	61.2	24.0	15.3	22.8	22.2	8.8	14.8	21.7	46.2	33.9	24.6	23.5	20.3	55.5	74.7	62.1	91.7	46.1	53.7	68.9	16.8	17.3	11.8	17.9	44.2	35.5	19.8	20.6	29.3	21.6	27.1	59.9	44.3	30.7	63.7	27.7	42.4	36.8	29.1	26.5	27.2	18.5	29.2	12.9	31.8	34.4	45.9	22.2	39.1	32.3	25.7	41.2	30.4	30.1	42.4	26.7	21.2	27.5	41.5	16.0	43.0	25.5	31.4	57.2	44.2	41.3	17.1	11.3	28.9	39.0	20.5	40.1	33.1	23.7	21.1	27.7	23.4	18.9	12.6	16.1	56.2	12.0	60.2	20.1	46.1	73.0	48.7	41.4	91.7	44.1	55.5	44.5	43.1	74.7	45.6	53.7	49.8	62.1	46.1	70.7	36.8	44.2	68.9	17.1	19.4	14.1	18.4	15.1	13.7	17.1	15.1	18.0	14.8
SETD2	"FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A"	ENSG00000181555	"SET domain containing 2"	Q9BYW2	3	47016429-47163967	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase"	"Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042451	Approved		Approved	"Nuclear speckles,Cytosol"				"Nuclear speckles"	Cytosol	"HPA042451: AB_10806239"	"unprognostic (2.78e-1)"	"unprognostic (1.01e-1)"	"unprognostic (6.08e-2)"	"unprognostic (1.01e-1)"	"unprognostic (3.37e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.01e-2)"	"prognostic unfavourable (8.19e-4)"	"unprognostic (6.19e-2)"	"unprognostic (2.45e-1)"	"unprognostic (7.84e-2)"	"prognostic favourable (7.99e-6)"	"unprognostic (1.03e-1)"	"unprognostic (1.91e-1)"	"unprognostic (8.79e-2)"	"unprognostic (5.43e-2)"	13.2	10.5	12.2	15.2	15.4	20.0	11.7	22.4	16.4	13.4	14.0	9.1	12.9	9.5	15.8	7.5	10.8	11.4	8.7	8.8	10.6	6.8	11.4	10.3	10.4	11.8	11.7	9.5	16.0	13.4	21.4	16.3	10.7	11.3	12.4	10.9	7.7	12.7	14.8	27.6	12.5	11.5	11.9	9.8	13.8	10.4	12.8	12.8	23.2	15.8	5.5	12.8	16.1	15.5	4.8	2.6	6.0	2.3	7.1	3.9	1.0	11.4	9.0	15.2	7.8	9.1	10.6	6.4	10.6	10.3	12.4	11.3	9.5	7.5	25.3	6.6	14.5	7.0	16.4	10.1	16.8	14.5	6.5	25.9	15.1	7.3	6.8	19.4	15.0	9.1	9.7	12.2	15.2	11.4	16.6	9.6	10.1	6.0	14.2	2.6	11.5	7.5	9.4	14.7	13.1	6.2	15.1	6.6	10.5	17.8	7.0	6.6	7.4	14.4	14.6	13.6	10.2	11.6	16.8	12.2	13.6	25.5	7.9	11.1	7.9	2.4	2.2	5.2	3.9	2.3	2.4	3.7	2.4	3.0	2.5	4.8	3.5	3.0	6.0	7.1	1.9	2.6	1.0	1.0	12.2	15.4	22.4	16.4	10.6	6.8	11.7	9.5	11.3	12.8
SH2B3	"IDDM20, LNK"	ENSG00000111252	"SH2B adaptor protein 3"	Q9UQQ2	12	111405948-111451623	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Diabetes mellitus"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HMC-1: 31.8;hTEC/SVTERT24-B: 36.4;U-87 MG: 55.3;WM-115: 42.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005483	Approved		Approved	Nucleoplasm				Nucleoplasm		"HPA005483: AB_1079260"	"unprognostic (2.77e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.20e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.09e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.18e-1)"	"unprognostic (4.65e-2)"	"unprognostic (8.17e-3)"	"unprognostic (9.08e-2)"	"prognostic unfavourable (6.20e-4)"	"unprognostic (2.86e-1)"	"unprognostic (3.89e-3)"	"unprognostic (1.11e-1)"	"unprognostic (2.24e-2)"	17.6	9.0	7.9	13.7	7.9	34.4	19.8	3.8	9.3	8.9	7.5	7.2	3.1	5.3	8.0	7.1	5.6	7.5	12.7	15.3	5.8	5.5	9.2	12.5	17.6	27.8	6.6	4.0	8.2	11.0	4.7	7.6	16.1	5.2	8.4	9.3	8.7	5.0	4.2	10.2	3.6	10.3	9.1	7.8	31.7	5.5	13.3	6.8	9.5	10.2	3.2	11.8	10.0	5.8	1.8	6.1	3.8	10.3	2.3	1.7	1.9	2.2	1.3	1.8	1.8	6.3	9.5	1.2	7.4	20.3	5.7	6.1	2.1	1.3	3.9	5.3	11.2	0.4	1.4	4.2	9.2	3.2	0.6	13.2	0.6	1.5	6.2	5.8	31.8	5.6	0.9	36.4	3.3	30.4	9.5	1.5	20.6	0.8	2.3	11.6	2.8	5.4	2.3	4.1	2.5	2.7	0.9	1.2	1.2	1.3	0.1	10.6	0.9	8.3	23.5	5.2	2.9	4.5	12.0	3.6	3.7	4.4	55.3	4.2	42.2	1.1	4.3	1.5	1.6	10.3	1.4	1.8	1.4	1.7	5.9	0.7	1.0	1.3	3.8	2.3	7.6	6.1	0.5	1.9	7.9	7.9	3.8	9.3	5.8	5.5	6.6	4.0	5.2	6.8
SMAD2	"JV18-1, MADH2, MADR2"	ENSG00000175387	"SMAD family member 2"	Q15796	18	47808957-47931146	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025507, HPA067203, CAB073546"	Approved		Supported	Nucleoplasm,Nucleoli,Cytosol				"Nucleoplasm, Nucleoli, Cytosol"		"CAB025507: , CAB073546: , HPA067203: "	"unprognostic (1.55e-1)"	"unprognostic (2.49e-1)"	"unprognostic (1.43e-2)"	"unprognostic (9.82e-3)"	"unprognostic (9.88e-2)"	"unprognostic (1.06e-1)"	"prognostic unfavourable (9.44e-5)"	"unprognostic (1.91e-2)"	"unprognostic (7.59e-2)"	"unprognostic (1.41e-3)"	"unprognostic (6.46e-2)"	"unprognostic (4.91e-2)"	"unprognostic (9.20e-3)"	"unprognostic (2.68e-1)"	"unprognostic (6.13e-2)"	"unprognostic (3.20e-2)"	"unprognostic (6.28e-2)"	38.5	39.2	29.0	26.2	25.9	19.6	31.4	19.5	28.9	28.8	34.2	29.4	28.9	21.5	26.6	26.3	33.5	28.8	25.7	31.1	26.1	27.1	26.4	20.9	28.3	23.8	30.9	24.3	36.6	28.1	25.7	24.4	34.8	28.6	27.8	29.8	31.7	29.7	28.7	33.9	28.0	26.4	34.6	35.4	34.1	26.3	29.2	26.2	60.7	46.1	23.6	31.5	35.1	35.7	12.0	21.8	28.9	24.7	24.5	25.9	19.7	22.4	32.2	19.7	19.0	31.5	38.5	22.5	24.5	29.4	25.6	29.9	12.3	21.5	34.9	17.6	31.0	24.8	22.1	27.3	34.3	37.9	11.3	29.6	48.7	19.9	36.7	41.1	30.3	28.4	35.3	21.9	50.7	28.2	13.7	29.3	31.4	14.6	28.2	19.8	9.6	7.7	20.6	28.7	23.8	57.4	38.7	18.2	21.4	29.5	20.2	24.0	15.3	27.4	31.5	38.0	21.9	10.3	17.8	28.7	27.5	30.4	26.3	28.1	27.7	28.9	22.6	25.0	16.9	24.7	21.2	12.0	23.1	20.9	21.8	9.4	25.8	19.8	22.7	24.5	20.8	15.5	25.9	19.7	29.0	25.9	19.5	28.9	26.1	27.1	30.9	24.3	28.6	26.2
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019154	Approved		Supported	Nucleoplasm,Centrosome,Cytosol				"Nucleoplasm, Cytosol"	Centrosome	"HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favourable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"	25.6	17.5	16.0	14.0	16.7	11.4	24.9	29.7	16.0	27.9	22.6	17.9	21.3	15.1	28.2	18.8	21.7	20.5	17.5	19.6	15.3	11.5	21.0	22.0	20.1	16.0	17.2	13.3	30.5	25.0	30.0	28.9	30.6	14.2	27.8	17.4	18.4	23.1	22.8	39.7	18.2	23.4	27.6	13.9	21.7	19.3	17.6	18.4	38.8	35.0	13.9	18.1	29.0	24.1	3.6	3.6	3.4	1.8	2.9	4.7	1.3	8.5	11.3	30.7	8.8	12.7	19.6	17.3	15.0	16.5	20.2	25.4	6.9	2.0	14.2	4.5	13.0	14.1	17.2	6.7	21.5	12.3	9.7	9.8	11.3	7.9	12.6	17.1	7.7	8.9	11.4	9.9	14.6	14.6	11.0	13.1	11.9	4.5	10.1	4.9	16.0	7.1	13.2	15.6	13.9	9.7	3.7	19.0	11.3	14.0	2.6	9.3	7.0	10.0	11.0	17.1	7.9	4.3	9.9	19.7	13.7	12.3	11.1	6.7	11.3	0.8	1.8	1.8	3.2	1.1	3.7	2.2	3.3	2.6	3.6	3.6	4.0	4.7	3.4	2.9	1.3	2.9	4.3	1.3	16.0	16.7	29.7	16.0	15.3	11.5	17.2	13.3	14.2	18.4
SMARCA4	"BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2"	ENSG00000127616	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4"	P51532	19	10960825-11079426	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB004208	Supported		Supported	Nucleoplasm			260000	Nucleoplasm		"CAB004208: AB_626762"	"unprognostic (2.68e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.43e-3)"	"unprognostic (1.40e-1)"	"unprognostic (6.33e-3)"	"prognostic unfavourable (1.11e-4)"	"unprognostic (7.19e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.80e-3)"	"unprognostic (6.83e-3)"	"unprognostic (5.44e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"	10.3	12.4	15.5	18.0	21.3	20.5	10.9	29.1	28.0	13.2	12.8	16.6	9.7	14.3	16.6	9.4	24.7	15.7	12.8	11.6	14.4	17.7	13.0	9.9	13.0	18.1	17.1	16.8	13.6	13.4	18.1	11.5	14.6	16.1	13.3	9.4	17.3	18.2	12.5	21.9	20.4	12.0	10.6	16.1	13.2	14.5	22.2	12.4	58.2	15.5	10.1	21.5	15.2	12.6	9.8	11.2	8.6	13.5	11.4	13.7	5.9	20.5	1.1	36.7	34.7	7.2	6.1	16.1	14.3	8.6	17.5	13.0	28.7	0.9	48.3	22.2	12.5	15.1	28.6	17.7	9.7	19.8	21.5	38.5	18.2	33.3	10.9	27.9	19.2	10.3	8.6	14.7	15.2	15.6	34.4	18.2	13.7	42.0	46.2	23.9	37.3	31.1	49.3	23.2	25.0	11.2	26.1	41.8	37.9	15.2	19.6	16.3	16.6	20.9	20.7	26.1	13.6	23.8	23.6	37.7	41.8	48.0	14.8	26.8	22.2	8.1	8.3	8.6	13.7	9.5	12.2	7.4	10.4	11.6	8.5	9.8	11.4	11.2	5.2	11.4	13.5	11.2	8.8	5.9	15.5	21.3	29.1	28.0	14.4	17.7	17.1	16.8	16.1	12.4
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838008	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease mutation, Hypotrichosis, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"AF22: 19.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"				Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavourable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favourable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"	11.0	15.2	14.6	33.2	15.4	16.9	12.1	30.4	21.9	13.4	25.1	16.4	11.4	41.1	17.2	11.0	15.6	12.3	15.0	12.6	13.2	14.2	14.6	11.7	14.0	32.8	13.0	13.8	21.3	16.1	7.9	15.7	20.8	12.8	11.0	9.4	16.7	40.9	13.1	28.1	14.7	27.4	10.6	12.8	19.8	24.1	37.7	12.9	29.4	15.7	12.0	16.0	21.1	12.2	19.5	9.9	4.8	11.6	7.0	7.5	5.9	1.5	1.0	19.0	1.7	1.8	0.5	3.8	6.0	1.8	1.8	2.9	2.2	1.8	15.5	5.2	0.8	2.9	4.5	2.9	3.0	2.5	6.6	12.9	1.7	1.3	2.0	13.6	3.8	1.1	2.2	2.1	4.7	0.9	3.5	8.6	1.1	3.8	11.1	3.1	5.7	3.8	7.0	15.3	7.0	1.5	3.0	9.0	6.8	1.4	0.4	10.2	1.4	2.1	1.6	1.6	6.6	2.6	1.7	9.5	8.7	10.3	1.3	7.5	4.6	4.0	10.0	4.8	3.8	10.2	5.2	19.5	4.6	4.6	9.3	6.4	3.8	2.5	0.8	7.0	11.6	9.9	7.5	5.9	14.6	15.4	30.4	21.9	13.2	14.2	13.0	13.8	12.8	12.9
SMARCD1	"BAF60A, CRACD1, Rsc6p"	ENSG00000066117	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1"	Q96GM5	12	50084972-50100712	"Cancer-related genes, Predicted intracellular proteins"	Neurogenesis	"Chromatin regulator"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA004101	Supported		Supported	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"HPA004101: AB_1080026"	"unprognostic (1.88e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.11e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.76e-1)"	"prognostic unfavourable (2.53e-8)"	"unprognostic (3.62e-2)"	"unprognostic (1.44e-1)"	"unprognostic (4.23e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.10e-2)"	"unprognostic (1.20e-3)"	"unprognostic (2.18e-1)"	"unprognostic (3.45e-1)"	"unprognostic (1.38e-1)"	"unprognostic (5.04e-2)"	21.3	24.5	16.4	22.6	22.7	29.9	21.3	27.8	28.2	19.8	19.9	29.5	17.6	18.8	23.6	23.4	23.3	19.9	18.2	15.6	16.3	13.8	25.1	18.3	19.4	26.1	15.7	20.4	24.7	19.6	44.3	17.8	24.7	18.8	20.4	22.4	20.3	21.4	25.9	16.6	19.7	24.0	23.8	18.5	28.1	17.4	34.4	14.9	64.3	24.3	17.9	36.7	19.3	18.2	6.0	6.7	4.4	3.4	3.1	6.9	2.3	8.0	13.6	40.3	23.3	12.6	11.9	20.0	10.1	17.9	29.7	17.4	37.4	12.7	31.6	15.2	19.2	10.4	34.0	26.4	25.7	24.4	25.1	31.1	13.8	21.6	15.0	27.5	12.5	12.0	17.8	17.5	31.8	34.9	26.3	19.6	15.0	19.0	39.9	14.8	50.4	22.4	47.9	10.5	27.6	16.8	19.0	21.8	36.3	21.2	10.8	42.1	24.3	23.1	20.9	15.3	17.1	9.6	20.5	27.7	24.3	28.1	12.4	11.2	17.3	4.4	2.3	4.1	6.1	2.1	5.8	6.0	3.3	3.9	3.6	5.6	2.1	6.9	1.1	3.1	3.4	6.7	5.0	2.3	16.4	22.7	27.8	28.2	16.3	13.8	15.7	20.4	18.8	14.9
SMARCE1	BAF57	ENSG00000073584	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1"	Q969G3	17	40624962-40648864	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	Neurogenesis	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003916, CAB037318"	Supported		Supported	Nucleoplasm				Nucleoplasm		"CAB037318: AB_476780, HPA003916: AB_1857279"	"unprognostic (7.91e-2)"	"unprognostic (2.68e-2)"	"unprognostic (2.09e-2)"	"unprognostic (8.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.55e-2)"	"unprognostic (4.48e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-2)"	"unprognostic (2.04e-1)"	"unprognostic (9.80e-2)"	"unprognostic (5.93e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.27e-2)"	25.1	20.2	14.4	17.2	18.8	18.4	20.2	17.0	16.7	37.6	25.1	18.0	12.6	18.4	42.8	19.5	31.0	21.1	20.6	19.6	13.3	12.0	23.0	22.6	20.1	22.3	16.5	14.3	39.5	16.9	13.3	20.4	34.8	15.2	32.4	19.2	17.9	20.6	21.9	32.0	21.3	22.6	33.4	15.8	30.3	19.1	22.0	17.5	53.9	23.8	18.9	25.1	31.2	21.0	40.3	32.0	34.0	30.3	47.2	44.0	39.2	20.5	34.3	42.1	31.3	22.3	32.1	20.7	25.9	35.8	30.5	23.0	22.4	17.9	32.7	37.5	35.0	28.1	26.0	27.4	36.7	30.6	33.8	23.4	18.5	39.4	22.5	42.6	23.8	27.8	21.7	24.3	35.5	32.8	34.0	13.0	29.1	23.1	78.0	8.8	23.5	17.0	43.8	47.4	24.8	36.8	35.3	33.7	32.6	23.0	66.9	21.5	40.1	26.8	26.8	24.8	27.4	22.4	31.9	24.4	28.4	48.9	25.3	19.6	38.2	31.8	26.0	34.0	39.1	26.8	40.5	38.4	35.8	40.9	31.3	40.3	30.2	34.9	11.0	47.2	30.3	32.0	44.0	39.2	14.4	18.8	17.0	16.7	13.3	12.0	16.5	14.3	15.2	17.5
SPEN	"KIAA0929, MINT, RBM15C, SHARP"	ENSG00000065526	"Spen family transcriptional repressor"	Q96T58	1	15847864-15940460	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015825, HPA050257"	Supported		Enhanced	Nucleoplasm				Nucleoplasm		"HPA015825: AB_1856823, HPA050257: "	"unprognostic (3.91e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.76e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.48e-1)"	"unprognostic (3.06e-2)"	"unprognostic (6.93e-3)"	"unprognostic (2.26e-1)"	"unprognostic (4.26e-2)"	"unprognostic (4.88e-3)"	"unprognostic (1.71e-1)"	"unprognostic (5.98e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.49e-1)"	"unprognostic (1.66e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.83e-1)"	18.2	11.2	18.2	18.2	22.2	27.2	17.3	38.2	25.9	18.5	13.4	20.7	17.7	11.9	19.0	12.7	16.7	19.4	11.8	13.5	17.6	11.5	14.4	13.2	17.8	16.6	23.4	17.5	31.2	23.9	35.1	17.5	16.2	19.0	14.9	13.3	11.6	16.2	16.2	24.0	22.8	16.0	15.1	22.0	16.5	13.7	13.6	23.3	18.3	20.1	8.7	18.0	17.1	41.9	5.0	2.7	7.7	2.4	1.3	1.7	0.6	12.5	10.7	13.4	10.0	13.4	8.2	7.2	6.5	8.6	7.1	6.0	9.6	9.8	17.8	7.8	12.8	18.2	12.5	11.6	11.5	15.9	34.7	22.3	9.4	6.1	6.1	18.3	10.7	6.0	8.4	10.6	15.4	8.0	23.1	18.3	5.7	7.0	15.1	7.2	6.0	8.2	14.6	13.0	11.0	4.0	11.3	10.3	10.4	18.3	9.0	7.8	3.2	9.0	14.5	6.5	8.1	12.6	9.3	11.1	7.2	20.3	6.4	14.7	9.1	7.7	1.5	0.9	1.6	2.4	1.3	1.8	1.7	1.4	0.7	5.0	0.9	1.3	4.2	1.3	1.2	2.7	1.1	0.6	18.2	22.2	38.2	25.9	17.6	11.5	23.4	17.5	19.0	23.3
SRC	"ASV, c-src, SRC1"	ENSG00000197122	"SRC proto-oncogene, non-receptor tyrosine kinase"	P12931	20	37344685-37406050	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters"	"Cell adhesion, Cell cycle, Host-virus interaction, Immunity"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"A549: 35.5;HBEC3-KT: 33.0;PC-3: 32.1;RT4: 34.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"intermediate monocyte: 5.3;non-classical monocyte: 4.4"	"Group enriched"	"Detected in many"	6	"dendritic cells: 3.0;monocytes: 5.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004023, HPA030875"	Approved		Supported	"Plasma membrane,Cell Junctions,Cytosol"			20000000	"Plasma membrane, Cell Junctions"	Cytosol	"CAB004023: AB_2106059, HPA030875: "	"unprognostic (5.58e-2)"	"unprognostic (9.83e-2)"	"unprognostic (3.56e-1)"	"unprognostic (4.54e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.54e-2)"	"prognostic unfavourable (4.90e-5)"	"unprognostic (3.89e-2)"	"unprognostic (7.04e-2)"	"unprognostic (8.13e-2)"	"unprognostic (1.54e-2)"	"prognostic unfavourable (1.63e-4)"	"prognostic unfavourable (1.22e-4)"	"unprognostic (2.33e-2)"	"unprognostic (4.72e-2)"	"unprognostic (3.65e-2)"	"prognostic favourable (5.22e-5)"	6.9	17.5	12.8	11.1	12.0	5.4	9.9	6.4	16.0	16.0	16.4	3.5	15.1	29.5	20.3	9.7	16.2	14.2	42.1	5.8	11.3	6.6	13.4	2.9	10.4	7.0	3.3	9.9	15.8	19.1	6.6	11.3	6.3	5.1	19.9	13.1	13.1	7.5	22.5	3.4	7.7	28.1	27.2	3.6	12.2	29.8	27.3	4.8	4.0	6.6	10.5	10.4	26.4	20.0	0.3	3.0	0.1	5.3	0.6	0.1	1.6	7.6	35.5	8.1	7.3	3.1	4.9	17.0	7.1	6.1	8.6	5.5	13.3	6.9	0.2	4.4	12.8	14.0	4.9	33.0	3.4	0.0	4.4	1.9	1.2	20.7	7.4	0.1	3.0	5.3	11.2	5.6	7.5	7.8	0.2	0.0	1.4	5.2	1.8	0.2	3.8	32.1	8.3	2.1	0.2	3.6	34.0	7.6	27.5	8.0	11.3	8.8	10.1	2.8	11.5	10.4	7.0	3.8	6.3	0.1	0.2	0.1	7.3	0.0	7.7	0.0	2.6	0.0	0.0	5.3	0.0	0.3	0.0	0.1	1.1	0.3	0.0	0.0	0.1	0.6	4.4	3.0	0.1	1.6	12.8	12.0	6.4	16.0	11.3	6.6	3.3	9.9	5.1	4.8
STAG2	"SA-2, SA2, SCC3B"	ENSG00000101972	"Stromal antigen 2"	Q8N3U4	X	123960212-124422664	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis"		"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002857	Supported									"HPA002857: AB_1079861"	"unprognostic (1.62e-1)"	"unprognostic (1.01e-2)"	"unprognostic (6.75e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.37e-2)"	"unprognostic (2.70e-2)"	"unprognostic (3.77e-2)"	"unprognostic (9.67e-3)"	"unprognostic (4.68e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.24e-1)"	"unprognostic (3.38e-1)"	"unprognostic (1.59e-3)"	"unprognostic (2.81e-1)"	"unprognostic (2.77e-2)"	"unprognostic (1.63e-1)"	"unprognostic (3.97e-1)"	24.0	18.8	21.5	23.9	23.7	39.7	30.1	35.4	23.5	28.1	25.1	16.4	25.2	14.9	24.3	21.0	24.3	20.0	16.3	15.7	21.4	17.9	22.2	18.1	23.4	26.2	24.9	17.5	31.1	19.7	46.1	27.6	25.5	20.6	25.9	18.3	14.2	20.7	27.8	27.6	18.9	21.9	25.9	30.6	26.7	17.6	9.3	26.4	69.3	32.0	19.7	27.1	37.7	37.8	12.8	12.5	30.3	14.4	12.1	15.5	6.7	17.2	16.3	24.5	15.4	10.5	15.9	15.8	16.4	17.7	17.0	21.5	15.1	18.5	31.9	23.2	14.7	15.8	50.1	13.9	24.2	22.6	21.4	29.5	32.6	9.9	10.9	38.5	23.2	12.5	13.8	20.1	32.6	14.2	28.7	34.0	12.5	18.8	49.2	17.4	12.8	24.2	34.9	32.4	26.6	13.2	33.0	22.1	17.7	37.0	13.8	19.4	8.2	17.7	17.3	0.1	9.1	20.0	18.6	14.7	22.1	40.1	10.7	23.7	17.1	16.8	10.2	18.1	10.8	13.1	12.6	10.0	11.2	10.1	12.5	12.8	15.5	12.4	30.3	12.1	14.4	11.2	8.7	6.7	21.5	23.7	35.4	23.5	21.4	17.9	24.9	17.5	20.6	26.4
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228435	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 11.7"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: "	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favourable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favourable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"	13.4	13.7	13.5	11.8	12.4	19.3	16.7	17.8	16.0	12.2	16.1	8.3	19.8	18.1	10.8	8.7	15.1	10.0	11.8	15.3	12.6	9.8	10.7	22.1	9.4	12.5	9.7	10.4	11.0	16.8	10.7	11.6	12.2	9.9	12.2	5.3	11.9	16.0	12.2	49.2	16.8	18.0	7.7	7.6	16.9	15.5	59.8	7.5	11.8	12.4	14.5	19.0	11.4	9.8	2.7	1.9	11.7	6.3	1.9	1.8	0.5	21.1	10.2	7.8	14.7	7.4	6.7	16.5	10.3	10.8	9.7	10.4	8.3	14.8	13.9	11.5	10.8	13.7	7.6	15.9	3.0	25.9	18.7	14.2	0.6	10.5	15.9	14.2	23.8	12.2	11.6	7.5	11.1	9.7	26.5	19.1	5.5	15.8	13.7	14.4	14.9	12.6	21.7	8.3	15.5	8.8	15.5	18.1	13.0	0.0	7.7	11.1	12.1	23.4	13.1	10.1	11.4	19.7	16.4	37.6	15.8	10.4	10.0	19.0	10.3	2.0	4.2	4.5	0.6	6.0	0.4	2.7	1.0	1.8	1.9	1.0	1.0	0.9	11.7	1.9	6.3	1.0	0.7	0.5	13.5	12.4	17.8	16.0	12.6	9.8	9.7	10.4	9.9	7.5
TBX3	"TBX3-ISO, UMS, XHL"	ENSG00000135111	"T-box 3"	O15119	12	114670254-114684164	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"seminal vesicle: 117.7"	"Cell line enhanced"	"Detected in many"		"BJ: 33.8;BJ hTERT+: 32.2;RT4: 42.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in many"			"HPA005799, HPA075876"			Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA005799: AB_1857817, HPA075876: "	"unprognostic (3.27e-1)"	"unprognostic (2.64e-1)"	"unprognostic (2.84e-1)"	"unprognostic (1.11e-1)"	"unprognostic (3.40e-2)"	"unprognostic (5.97e-3)"	"unprognostic (1.56e-1)"	"unprognostic (2.99e-2)"	"unprognostic (9.43e-2)"	"unprognostic (1.15e-1)"	"unprognostic (3.35e-1)"	"unprognostic (3.06e-1)"	"unprognostic (3.64e-3)"	"unprognostic (1.09e-3)"	"unprognostic (1.43e-1)"	"unprognostic (1.01e-1)"	"prognostic favourable (3.28e-4)"	4.3	60.5	0.9	3.3	1.9	0.0	19.9	0.7	2.3	18.2	12.2	1.7	69.6	14.2	13.1	18.7	1.9	7.5	5.0	6.2	1.2	1.5	4.1	15.1	12.6	0.8	1.2	0.5	15.6	1.1	0.3	5.3	67.8	1.6	32.3	1.5	2.6	7.3	117.7	4.2	4.8	19.4	9.7	1.4	2.6	2.2	3.5	1.2	0.5	36.3	7.3	3.5	24.6	25.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.7	5.9	0.0	0.0	8.9	12.3	13.4	33.8	32.2	13.1	13.0	5.3	1.4	0.0	0.5	5.8	1.5	2.8	1.2	16.2	0.0	4.0	0.0	1.5	15.4	2.9	0.0	0.0	5.4	0.8	4.4	9.1	0.1	1.2	0.0	1.1	0.5	0.0	0.1	0.0	1.8	0.0	0.0	0.8	0.0	42.2	2.2	6.5	4.8	2.2	1.1	1.6	0.0	0.0	4.0	2.6	2.2	10.9	0.0	0.0	0.0	8.4	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	1.9	0.7	2.3	1.2	1.5	1.2	0.5	1.6	1.2
TET2	"FLJ20032, KIAA1546"	ENSG00000168769	"Tet methylcytosine dioxygenase 2"	Q6N021	4	105145875-105279816	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 29.0"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 29.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA043135	Supported		Approved	Nucleoplasm				Nucleoplasm		"HPA043135: AB_10794177"	"unprognostic (6.83e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.69e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.15e-2)"	"unprognostic (5.88e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.19e-3)"	"unprognostic (1.15e-2)"	"unprognostic (1.57e-2)"	"unprognostic (5.77e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.70e-3)"	"unprognostic (6.10e-2)"	"unprognostic (1.89e-1)"	"unprognostic (9.15e-2)"	"unprognostic (7.84e-2)"	9.9	6.1	8.7	11.9	11.4	26.3	8.0	4.1	10.0	9.6	7.4	10.1	5.8	8.2	10.1	7.4	16.2	9.2	6.6	6.8	9.0	4.2	6.7	5.5	9.9	9.8	13.7	5.7	8.5	7.0	7.4	29.0	12.4	9.1	6.5	8.0	4.7	13.5	8.2	9.8	16.0	10.2	7.8	15.5	12.9	6.8	3.2	14.6	9.3	7.2	6.9	8.7	9.8	12.3	2.8	5.1	29.0	7.0	2.6	2.1	1.4	4.7	3.1	10.4	10.6	1.9	4.3	4.3	3.4	4.6	4.9	4.8	3.1	6.4	0.5	3.9	4.3	4.6	10.1	6.0	5.6	6.2	2.7	6.6	5.9	1.1	5.3	15.1	11.1	3.6	8.1	4.7	6.1	6.5	7.1	12.5	4.2	3.6	2.5	4.1	2.3	1.9	7.8	5.2	0.9	4.5	10.0	7.4	6.1	3.8	9.8	0.6	4.4	10.9	8.4	7.5	6.8	2.1	5.8	8.4	6.0	6.3	4.6	3.7	7.3	10.8	7.0	7.2	2.1	5.5	0.8	2.6	1.2	1.2	5.1	2.8	1.0	1.6	29.0	2.6	6.4	4.5	1.5	1.4	8.7	11.4	4.1	10.0	9.0	4.2	13.7	5.7	9.1	14.6
TGFBR2	"MFS2, TBR-ii, TBRII"	ENSG00000163513	"Transforming growth factor beta receptor 2"	P37173	3	30606502-30694142	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins"	"Apoptosis, Differentiation, Growth regulation"	"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB073537			Supported	"Plasma membrane"			560000	"Plasma membrane"		"CAB073537: "	"unprognostic (1.74e-1)"	"unprognostic (1.84e-2)"	"unprognostic (3.70e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.62e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.65e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.81e-2)"	"unprognostic (8.81e-2)"	"unprognostic (8.02e-2)"	91.8	24.6	6.7	24.6	10.3	7.3	88.3	3.6	7.3	36.5	42.6	9.8	18.6	13.2	42.6	23.3	36.2	28.4	42.6	73.5	6.9	5.2	32.6	21.9	52.6	75.7	12.6	3.7	22.2	26.0	17.4	10.3	24.2	9.9	35.2	17.5	27.9	22.5	19.5	34.9	17.0	31.3	37.2	12.0	68.7	26.8	15.4	8.2	19.3	40.9	16.8	26.9	48.0	82.0	5.3	6.8	20.0	6.6	1.4	19.7	3.9	2.4	14.4	0.9	0.0	53.4	80.5	2.4	12.5	17.6	4.3	4.3	3.2	13.3	0.3	45.3	16.8	5.0	0.6	18.3	7.2	1.0	1.3	1.4	1.6	16.2	22.8	2.2	11.8	69.5	16.3	18.6	18.0	46.7	0.2	0.0	65.8	0.2	2.3	1.6	0.4	5.8	2.0	5.8	0.3	23.2	5.8	0.0	0.9	3.7	1.0	3.5	0.0	2.4	60.3	21.2	5.2	9.6	4.7	0.4	0.0	2.0	12.7	2.5	8.5	6.9	2.9	20.0	3.5	3.0	3.2	4.0	5.4	4.2	2.6	5.3	19.7	9.1	12.6	1.4	6.6	6.8	1.2	3.9	6.7	10.3	3.6	7.3	6.9	5.2	12.6	3.7	9.9	8.2
TMEM127	"FLJ20507, FLJ22257"	ENSG00000135956	"Transmembrane protein 127"	O75204	2	96248516-96265994	"Cancer-related genes, Disease related genes, Predicted membrane proteins"			"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (5.15e-3)"	"unprognostic (2.67e-1)"	"unprognostic (1.72e-2)"	"unprognostic (6.51e-2)"	"unprognostic (5.82e-2)"	"unprognostic (2.05e-1)"	"prognostic unfavourable (6.59e-4)"	"unprognostic (6.73e-2)"	"unprognostic (4.25e-1)"	"unprognostic (1.06e-2)"	"unprognostic (7.50e-2)"	"unprognostic (2.17e-1)"	"prognostic favourable (6.69e-5)"	"unprognostic (3.59e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.15e-2)"	"unprognostic (3.65e-2)"	27.6	27.8	16.4	18.7	22.6	31.8	26.1	20.2	40.6	22.9	27.2	18.7	27.3	22.2	24.8	18.9	29.3	18.2	24.2	45.6	15.6	16.5	29.3	43.3	22.9	19.8	14.8	13.1	23.4	26.2	50.7	23.7	21.6	21.4	20.5	21.5	26.5	29.8	31.5	18.7	24.0	41.8	24.4	11.2	28.5	20.0	12.7	12.8	19.6	22.4	19.3	26.9	26.1	22.3	2.4	4.5	14.7	6.7	1.5	3.4	2.9	11.8	16.0	8.5	13.1	37.8	19.2	15.8	15.6	28.0	16.6	15.3	15.8	16.9	7.4	22.9	30.6	19.1	9.8	14.4	11.7	14.9	7.7	12.9	7.7	15.4	24.4	10.9	23.3	23.2	20.6	20.6	15.3	18.8	7.9	16.0	16.9	13.5	7.1	6.9	11.6	17.3	6.7	10.7	11.0	18.6	20.4	9.6	10.1	11.4	27.2	13.0	10.1	11.7	22.0	27.8	15.9	24.0	10.7	12.2	11.7	5.9	18.5	12.9	14.7	4.1	6.5	7.9	3.1	6.7	3.4	2.1	2.3	3.3	4.5	2.4	1.8	2.4	14.7	1.5	5.3	2.7	1.6	2.9	16.4	22.6	20.2	40.6	15.6	16.5	14.8	13.1	21.4	12.8
TNFAIP3	"A20, OTUD7C"	ENSG00000118503	"TNF alpha induced protein 3"	P21580	6	137867188-137883312	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Inflammatory response, Ubl conjugation pathway"	"DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 112.4"	"Cell line enhanced"	"Detected in many"		"Karpas-707: 48.4;REH: 42.0;U-266/84: 36.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA002116, HPA067479"	Approved		Supported	Vesicles				Vesicles		"HPA002116: AB_1858162, HPA067479: "	"unprognostic (5.50e-3)"	"unprognostic (9.98e-3)"	"unprognostic (3.06e-2)"	"unprognostic (1.01e-2)"	"unprognostic (4.01e-2)"	"unprognostic (9.47e-2)"	"unprognostic (5.01e-3)"	"unprognostic (4.40e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.06e-1)"	"prognostic unfavourable (6.05e-4)"	"unprognostic (6.06e-2)"	"unprognostic (3.55e-3)"	"unprognostic (1.27e-1)"	"unprognostic (6.29e-2)"	27.4	6.0	1.5	58.6	1.8	112.4	17.2	0.4	1.5	7.7	15.7	3.2	2.6	5.1	9.7	7.3	12.7	12.1	17.0	11.7	2.1	1.3	6.8	8.1	45.1	38.8	2.1	2.6	37.5	7.2	2.1	3.7	14.5	4.6	13.8	6.3	7.2	8.2	3.5	10.7	20.5	17.2	8.2	3.8	25.9	8.0	9.3	2.1	38.6	5.7	9.2	31.4	23.3	9.5	7.1	18.6	10.0	9.7	7.5	20.5	9.0	8.9	1.5	0.5	0.8	3.0	5.1	2.1	5.1	20.0	1.4	1.8	9.9	3.0	2.0	13.2	5.9	6.8	0.3	14.8	2.6	14.6	0.5	2.0	5.2	5.8	3.3	2.7	3.7	4.7	2.1	16.9	16.1	0.8	4.1	48.4	2.4	0.5	14.7	11.5	0.3	0.4	42.0	10.4	1.4	4.4	4.3	0.2	0.0	1.0	1.5	4.4	1.0	3.4	4.0	14.5	1.7	12.9	2.9	15.6	36.1	4.1	5.3	3.5	1.8	5.6	9.7	5.5	14.8	7.1	20.5	6.2	15.1	13.3	10.3	7.1	10.0	7.4	10.0	7.5	3.7	18.6	14.7	9.0	1.5	1.8	0.4	1.5	2.1	1.3	2.1	2.6	4.6	2.1
TNFRSF14	"ATAR, CD270, HVEA, HVEM, LIGHTR, TR2"	ENSG00000157873	"TNF receptor superfamily member 14"	Q92956	1	2555639-2565382	"Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins"	"Adaptive immunity, Host-virus interaction, Immunity, Innate immunity"	"Host cell receptor for virus entry, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"CAPAN-2: 14.3;HDLM-2: 14.4;HHSteC: 16.9;Karpas-707: 13.3;SK-MEL-30: 27.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"HPA006404, CAB026150, CAB030007"	Approved		Approved	"Cytosol,Rods & Rings"				Cytosol	"Rods & Rings"	"CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348"	"prognostic favourable (4.39e-5)"	"unprognostic (3.48e-2)"	"unprognostic (1.53e-2)"	"prognostic favourable (8.01e-6)"	"unprognostic (1.11e-2)"	"unprognostic (6.83e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.32e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.31e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.72e-2)"	"unprognostic (1.58e-1)"	"prognostic favourable (7.79e-6)"	15.9	24.9	4.9	38.9	2.8	11.0	21.9	2.0	4.5	16.8	36.3	3.2	18.5	36.3	15.2	20.5	13.7	12.3	36.7	12.7	4.9	2.5	19.3	20.5	30.3	33.2	3.6	5.7	12.8	7.3	3.5	9.3	8.3	3.9	21.5	8.2	44.1	20.9	22.6	5.2	8.4	41.9	14.6	4.1	36.7	16.7	5.9	2.7	23.5	10.8	10.6	25.0	15.4	17.2	18.2	9.7	30.2	25.8	8.1	25.1	14.2	1.3	0.1	0.1	2.3	5.0	2.7	0.7	0.7	2.3	1.3	1.9	0.2	14.3	0.8	0.1	2.1	1.3	0.0	0.8	0.2	14.4	0.0	8.4	0.4	2.6	16.9	1.1	10.4	2.6	1.4	0.7	0.1	3.7	1.1	13.3	1.2	0.0	4.6	1.3	0.0	1.2	3.8	0.0	4.1	0.2	2.0	0.4	0.0	0.5	0.1	27.9	0.4	0.3	9.4	0.2	0.6	0.2	0.1	10.8	2.6	0.4	2.3	1.2	1.0	3.0	15.1	8.2	17.2	25.8	14.9	16.6	18.0	14.8	9.7	18.2	17.3	14.9	30.2	8.1	24.1	8.7	25.1	14.2	4.9	2.8	2.0	4.5	4.9	2.5	3.6	5.7	3.9	2.7
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687550	"Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 102.6"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: , HPA051244: , HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favourable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavourable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	18.5	11.1	6.0	28.6	6.8	9.0	17.5	2.5	7.3	18.5	14.6	6.8	8.3	9.7	20.3	15.0	25.3	16.7	22.6	8.1	5.0	3.8	10.6	20.8	11.2	26.0	6.6	3.1	33.8	13.8	4.9	6.0	22.8	6.9	16.5	14.5	9.9	15.3	16.1	12.5	24.6	14.0	12.8	6.2	24.2	12.0	14.1	6.9	102.6	13.2	23.5	31.2	16.9	15.0	15.2	19.6	2.2	14.1	11.0	11.3	8.2	19.2	35.6	19.4	14.0	9.1	10.8	20.6	6.9	15.6	19.2	24.3	1.0	9.9	45.3	31.5	13.6	42.5	28.2	19.1	18.0	10.1	18.9	18.3	20.0	16.9	27.4	0.4	9.5	13.7	22.2	9.3	25.7	18.8	0.9	1.7	9.8	34.2	30.7	22.4	19.6	0.7	59.7	13.7	15.7	14.3	21.3	11.6	20.0	22.8	15.4	5.9	26.7	1.7	24.3	23.0	7.6	0.3	11.6	11.9	8.7	19.5	6.0	2.3	19.4	0.8	13.3	2.2	9.1	14.1	11.1	15.2	9.4	10.2	19.6	14.5	9.9	10.8	1.7	11.0	11.9	17.9	11.3	8.2	6.0	6.8	2.5	6.4	5.0	3.8	6.6	3.1	6.9	6.9
TP63	"EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L"	ENSG00000073282	"Tumor protein p63"	Q9H3D4	3	189631416-189897279	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease mutation, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skeletal muscle: 83.2;skin 1: 54.2"	"Group enriched"	"Detected in some"	5	"HaCaT: 23.3;HBEC3-KT: 44.6;hTCEpi: 33.8;hTERT-HME1: 32.3;RT4: 49.0"	"Group enriched"	"Detected in many"	11	"cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2"	"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000083, HPA006288, HPA006289, HPA007009, HPA007010"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336"	"prognostic favourable (1.07e-4)"	"unprognostic (1.30e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.02e-1)"	"unprognostic (4.38e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.78e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.09e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.87e-5)"	"unprognostic (1.86e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.74e-3)"	2.9	0.1	0.2	0.7	0.1	0.0	7.2	0.1	0.2	9.5	0.1	0.1	5.7	0.0	0.3	8.0	33.7	0.3	0.0	0.2	0.1	0.1	0.4	0.1	1.2	0.2	0.1	0.2	0.1	0.1	0.0	0.3	7.8	0.8	9.6	0.0	0.3	9.0	7.8	83.2	54.2	0.1	2.7	0.6	0.1	0.1	1.2	0.0	9.0	0.4	36.7	26.1	9.6	19.2	3.7	1.3	3.0	0.9	1.2	1.2	0.2	0.6	1.2	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.1	0.0	23.3	0.0	44.6	0.0	0.3	0.0	0.5	0.3	0.1	0.0	0.0	0.1	0.0	33.8	0.0	32.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	49.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	6.8	0.1	0.3	0.1	0.0	0.2	2.0	0.4	1.1	0.9	0.5	0.7	3.7	1.2	1.0	0.4	1.7	0.8	0.7	3.0	1.2	0.9	1.3	0.8	0.2	0.2	0.1	0.1	0.2	0.1	0.1	0.1	0.2	0.8	0.0
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol				Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: "	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavourable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favourable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favourable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"	10.4	13.6	15.8	8.8	26.8	13.6	11.4	32.1	28.3	12.7	10.8	22.6	7.9	9.1	14.6	12.3	10.9	12.4	9.7	17.6	13.0	12.1	13.1	9.4	11.6	10.2	12.5	15.1	21.2	12.1	15.9	19.5	15.8	21.1	11.8	12.6	13.1	11.6	10.4	20.0	13.8	11.2	14.2	12.4	13.7	10.6	36.2	14.9	10.5	16.2	8.6	14.2	10.9	11.1	2.8	3.1	4.8	7.0	4.9	7.1	2.6	6.1	7.3	10.0	8.2	10.3	9.8	18.8	8.3	13.4	8.7	8.6	12.4	7.2	14.4	3.6	15.8	16.0	11.7	8.4	8.9	6.9	6.2	4.6	14.5	10.1	12.3	6.7	6.2	10.5	6.4	11.1	13.6	10.0	8.0	7.9	9.9	11.4	6.0	5.8	13.7	6.1	7.3	18.9	8.1	3.9	8.1	5.0	7.7	9.7	6.1	4.8	11.0	4.0	10.3	14.3	8.6	8.5	5.6	4.4	9.8	14.0	8.1	4.0	6.3	4.1	4.4	4.8	6.5	7.0	7.1	1.9	3.6	5.7	3.1	2.8	5.9	5.3	1.7	4.9	3.2	1.8	5.7	2.6	15.8	26.8	32.1	28.3	13.0	12.1	12.5	15.1	21.1	14.9
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047465-2089487	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol				Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: "	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favourable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"	13.9	11.9	16.9	12.4	20.0	10.9	13.2	35.1	26.9	20.5	17.0	19.4	17.9	14.0	20.1	12.2	13.0	18.6	15.0	14.0	13.3	8.8	11.8	9.8	12.7	10.1	13.8	14.7	21.1	16.1	20.0	18.1	10.6	14.6	13.8	10.8	16.7	22.9	19.6	31.7	14.5	13.2	13.5	11.4	12.9	16.6	21.4	12.9	14.1	20.1	11.3	10.9	18.0	14.0	4.7	5.6	7.7	4.9	3.6	7.0	3.7	7.2	11.6	16.1	18.2	19.2	16.2	13.6	17.4	11.9	13.1	11.2	13.9	13.8	10.9	15.5	14.3	12.0	9.6	12.6	9.8	8.3	15.8	10.3	22.5	5.7	13.2	12.8	12.5	19.1	8.0	10.6	7.9	12.3	10.0	9.8	11.6	14.4	15.2	3.8	16.7	11.4	24.2	17.6	13.9	5.3	6.5	12.2	23.1	24.8	16.4	8.8	15.0	9.5	19.4	13.8	9.4	12.3	8.8	21.9	21.8	21.8	5.7	5.2	16.3	6.2	4.9	5.4	7.0	4.7	6.7	4.4	4.4	4.1	5.6	4.7	3.1	4.8	7.7	3.6	3.7	1.5	3.2	3.7	16.9	20.0	35.1	26.9	13.3	8.8	13.8	14.7	14.6	12.9
UBR5	"DD5, EDD, EDD1, HYD, KIAA0896"	ENSG00000104517	"Ubiquitin protein ligase E3 component n-recognin 5"	O95071	8	102253012-102412841	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA053688			Supported	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"HPA053688: "	"unprognostic (3.79e-3)"	"unprognostic (7.44e-3)"	"unprognostic (1.25e-1)"	"unprognostic (2.10e-2)"	"unprognostic (2.44e-2)"	"unprognostic (1.41e-1)"	"prognostic unfavourable (1.26e-4)"	"unprognostic (2.50e-1)"	"unprognostic (1.75e-2)"	"unprognostic (7.54e-3)"	"unprognostic (8.29e-3)"	"unprognostic (3.84e-2)"	"unprognostic (6.64e-2)"	"unprognostic (3.16e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.45e-1)"	27.0	16.7	27.1	29.5	31.7	30.3	29.2	40.8	32.8	24.9	25.0	19.1	21.1	14.4	26.8	24.0	23.8	22.0	17.6	22.7	25.5	15.3	17.9	17.0	24.2	29.6	21.9	20.6	29.7	22.2	32.4	25.5	25.0	23.6	20.2	17.1	19.7	22.9	21.8	39.9	29.7	22.4	29.3	17.5	21.9	21.1	39.7	28.3	37.9	20.3	15.9	27.0	27.5	28.6	5.0	4.0	6.3	5.5	2.4	7.1	2.1	23.2	10.4	20.2	10.3	19.9	20.3	18.6	17.6	15.6	13.8	12.1	10.4	15.7	46.4	15.2	16.5	14.2	17.2	15.3	19.4	20.0	8.4	38.7	14.2	18.7	17.7	12.0	21.4	23.2	15.3	14.2	24.8	16.5	18.6	26.4	13.5	21.0	30.5	14.4	15.2	11.8	17.8	11.9	22.0	12.6	22.9	14.9	12.4	12.3	12.0	12.2	19.2	12.8	16.5	14.7	17.2	13.2	12.2	14.1	13.6	47.7	14.6	18.8	11.9	3.1	3.4	5.0	5.6	3.4	5.6	5.0	6.0	5.9	4.0	3.9	4.8	7.1	6.3	2.4	5.5	3.6	7.1	2.1	27.1	31.7	40.8	32.8	25.5	15.3	21.9	20.6	23.6	28.3
USP8	"HumORF8, KIAA0055, SPG59, UBPY"	ENSG00000138592	"Ubiquitin specific peptidase 8"	P40818	15	50424380-50514419	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Ubl conjugation pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Cushing syndrome, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050215	Approved		Supported	"Golgi apparatus,Cytosol"				"Golgi apparatus"	Cytosol	"HPA050215: "	"unprognostic (5.81e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.46e-1)"	"unprognostic (9.58e-2)"	"unprognostic (2.35e-2)"	"unprognostic (2.91e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.96e-1)"	"unprognostic (1.68e-2)"	"unprognostic (5.08e-2)"	"unprognostic (2.94e-1)"	"unprognostic (3.99e-2)"	"prognostic favourable (1.29e-5)"	"unprognostic (4.89e-2)"	"unprognostic (1.13e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.58e-1)"	19.4	21.9	21.0	20.6	20.6	21.6	18.1	27.3	21.6	21.4	23.9	13.8	19.5	20.2	22.1	17.4	22.3	17.4	15.5	17.4	19.7	18.2	28.2	26.4	17.0	25.4	21.8	15.2	21.9	16.7	42.6	43.2	29.1	29.7	16.7	18.9	10.7	19.9	17.9	24.3	17.8	32.1	19.2	29.3	30.3	17.7	27.5	26.1	28.9	24.1	12.7	20.9	22.3	18.4	16.7	10.6	38.1	15.1	9.5	11.9	6.9	11.0	15.9	8.9	15.7	16.3	18.3	12.4	15.9	18.9	15.5	18.4	10.6	7.3	11.7	12.3	18.2	21.5	12.2	11.9	18.4	10.2	8.1	21.6	14.8	10.9	16.8	14.4	14.6	14.2	14.3	13.7	23.3	15.0	12.3	14.2	14.5	22.7	9.2	5.7	10.2	7.3	8.4	16.6	17.5	14.7	26.1	11.4	10.4	16.8	25.1	20.8	13.7	17.7	17.0	16.1	9.1	49.6	21.0	11.1	23.1	12.9	12.9	29.2	15.5	38.1	13.3	22.4	11.1	12.4	10.7	16.5	11.4	11.1	10.6	16.7	11.9	10.7	22.7	9.5	15.1	9.9	8.5	6.9	21.0	20.6	27.3	21.6	19.7	18.2	21.8	15.2	29.7	26.1
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141008-10152220	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 53.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB005430, HPA031631, HPA031632"	Uncertain		Enhanced	Nucleoplasm,Cytosol				Nucleoplasm	Cytosol	"CAB005430: AB_2241850, HPA031631: , HPA031632: "	"prognostic unfavourable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavourable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favourable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"	13.8	17.4	18.1	29.2	18.4	24.3	15.4	25.8	21.4	13.3	19.8	19.3	14.5	15.9	15.1	13.6	16.4	14.3	18.9	10.5	17.1	18.5	13.7	16.3	14.6	27.9	13.5	12.3	15.2	22.5	13.8	14.6	18.8	12.8	15.1	16.6	12.5	21.8	13.7	14.8	14.0	22.3	13.4	17.0	22.6	16.2	17.9	11.2	39.2	16.9	11.5	29.3	15.4	19.1	5.4	3.9	8.0	4.1	4.4	4.3	1.7	6.7	6.5	14.3	8.8	13.3	10.3	53.6	5.9	8.5	7.6	9.0	7.6	8.4	23.8	8.1	8.0	5.8	13.2	8.3	9.4	11.4	12.0	18.5	10.5	10.5	12.6	16.3	14.8	10.3	9.5	10.1	12.8	8.7	16.4	18.1	7.5	12.2	15.5	12.0	9.6	8.3	19.7	12.6	11.9	9.3	17.4	5.4	17.9	12.5	6.7	7.2	13.2	20.7	7.5	7.6	10.1	7.0	9.3	12.9	26.4	38.0	8.4	19.5	6.9	2.6	4.1	3.3	3.8	2.5	3.6	4.1	2.9	4.3	3.9	5.4	2.5	2.7	8.0	4.4	3.2	2.4	3.1	1.7	18.1	18.4	25.8	21.4	17.1	18.5	13.5	12.3	12.8	11.2
WAS	"IMD2, THC, WASP, WASPA"	ENSG00000015285	"Wiskott-Aldrich syndrome"	P42768	X	48676596-48691427	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 30.7;lymphoid tissue: 55.9"	"Cell line enhanced"	"Detected in some"		"Daudi: 21.3;HMC-1: 45.7;MOLT-4: 19.4;NB-4: 21.1;RPMI-8226: 26.0;U-266/70: 24.2;U-937: 24.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"eosinophil: 20.3"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002022, CAB004290"	Enhanced		Approved	"Plasma membrane,Cytosol"			320000	"Plasma membrane"	Cytosol	"CAB004290: AB_628445, HPA002022: AB_1080581"	"unprognostic (1.43e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.36e-2)"	"prognostic favourable (4.95e-4)"	"unprognostic (9.89e-2)"	"prognostic favourable (3.78e-4)"	"unprognostic (5.12e-3)"	"unprognostic (7.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.40e-2)"	"unprognostic (3.60e-1)"	"prognostic unfavourable (5.58e-6)"	"unprognostic (2.24e-1)"	"unprognostic (2.37e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.71e-1)"	7.6	4.0	4.9	28.9	7.8	30.7	3.3	2.0	5.1	2.7	4.4	5.9	0.5	4.8	2.4	5.6	3.7	4.5	4.4	3.0	4.6	4.1	4.1	5.0	12.6	29.9	7.6	1.3	2.6	2.2	0.7	2.6	5.4	6.0	3.2	3.2	3.5	5.4	1.9	1.4	2.2	14.3	3.7	12.8	55.9	4.1	1.7	7.3	53.2	2.8	1.4	33.2	5.8	2.5	2.1	3.5	20.3	5.3	2.1	3.2	2.0	0.2	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	21.3	0.0	0.0	0.7	0.0	0.0	0.0	12.2	0.1	18.8	0.2	0.0	0.2	9.6	45.7	0.0	0.0	0.0	0.0	0.0	0.2	13.1	0.0	2.1	19.4	21.1	0.1	0.1	16.9	0.0	26.0	0.0	0.0	0.1	0.2	0.3	0.2	0.2	0.1	19.2	0.1	0.0	0.1	0.3	0.0	24.2	11.8	14.9	0.1	24.4	0.0	1.8	4.6	20.3	3.0	5.0	2.2	1.8	2.3	2.5	3.5	2.1	2.1	2.3	18.1	2.1	5.3	1.8	3.2	2.0	4.9	7.8	2.0	5.1	4.6	4.1	7.6	1.3	6.0	7.3
WRN	"RECQ3, RECQL2"	ENSG00000165392	"Werner syndrome RecQ like helicase"	Q14191	8	31033801-31173769	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028661	Approved		Supported	"Nuclear speckles"				"Nuclear speckles"		"HPA028661: AB_10602255"	"unprognostic (8.73e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.51e-3)"	"unprognostic (3.85e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.27e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.53e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.00e-2)"	"unprognostic (2.66e-1)"	10.1	9.2	5.6	8.5	6.6	15.6	11.1	10.7	7.3	14.2	8.0	7.7	7.7	5.5	24.4	8.8	7.6	9.7	6.9	7.0	5.9	4.0	5.1	7.7	7.2	6.7	8.2	5.3	12.0	9.9	7.8	28.1	8.5	7.0	8.6	7.8	8.3	10.8	7.8	7.7	10.2	7.0	12.1	14.9	8.9	8.3	10.4	7.3	11.8	7.9	6.3	9.3	10.8	8.7	3.9	2.7	1.3	1.9	2.9	6.2	1.6	6.4	6.3	13.1	8.3	7.8	12.5	8.3	7.3	7.1	8.9	9.3	4.0	3.9	15.1	6.7	7.3	3.3	8.1	5.2	13.4	4.2	6.9	15.4	6.0	3.3	9.8	9.1	5.7	9.1	5.8	8.5	10.2	8.6	24.3	9.6	8.2	4.1	18.9	4.4	11.2	4.6	10.9	9.9	6.0	3.7	7.0	2.8	7.5	8.8	5.0	6.9	3.5	4.5	13.7	9.7	6.0	5.0	6.1	2.5	2.7	19.0	7.2	7.2	6.6	1.2	1.9	1.3	3.3	1.9	6.2	3.9	3.8	3.3	2.7	3.5	2.5	3.2	0.5	2.9	0.8	2.0	2.8	1.6	5.6	6.6	10.7	7.3	5.9	4.0	8.2	5.3	7.0	7.3
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"Wilms tumor 1"	P19544	11	32387775-32435630	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 69.0;fallopian tube: 34.5;ovary: 53.4"	"Cell line enhanced"	"Detected in some"		"HEL: 13.2;HMC-1: 17.0;K-562: 11.9;NB-4: 31.9;THP-1: 15.3"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"pons and medulla: 0.5"	"Low region specificity"	"Detected in single"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm				Nucleoplasm		"CAB000327: AB_2304486, HPA035717: , HPA053848: "	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"	10.3	0.0	0.2	1.8	0.6	0.0	0.2	0.2	0.5	20.3	1.5	0.2	3.7	0.0	69.0	9.3	0.4	34.5	0.8	2.1	0.9	0.0	5.3	0.2	0.8	0.5	0.2	0.2	53.4	0.2	0.0	0.2	6.9	0.3	0.9	0.0	0.2	0.2	4.2	0.2	0.0	0.4	23.7	0.2	14.6	0.0	24.5	0.2	0.2	0.3	0.2	0.2	1.3	4.1	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.0	0.1	0.1	0.0	0.0	6.1	0.0	0.0	0.0	4.6	13.2	0.0	1.1	3.7	8.8	17.0	0.0	0.0	2.7	0.0	0.0	11.9	0.1	2.7	0.0	7.7	31.9	0.7	3.7	1.1	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	15.3	0.1	0.0	2.3	0.0	0.3	0.0	0.0	0.0	0.1	2.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.2	0.6	0.2	0.5	0.9	0.0	0.2	0.2	0.3	0.2
XPA	"XP1, XPAC"	ENSG00000136936	"XPA, DNA damage recognition and repair factor"	P23025	9	97674909-97697357	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000155, HPA056856"	Supported		Approved	"Nucleoplasm,Cytokinetic bridge"				Nucleoplasm	"Cytokinetic bridge"	"CAB000155: , HPA056856: "	"unprognostic (8.76e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.60e-1)"	"unprognostic (2.30e-2)"	"unprognostic (4.17e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.26e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.97e-3)"	"unprognostic (9.55e-3)"	"prognostic favourable (4.28e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.56e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.17e-1)"	18.7	17.5	20.1	17.1	21.0	10.6	17.4	26.8	20.8	20.3	25.2	17.2	11.7	20.6	25.5	15.4	18.9	15.0	19.5	12.9	17.2	15.3	24.9	24.2	14.8	16.7	18.6	17.5	17.2	14.5	23.0	23.1	12.8	17.7	20.3	13.6	16.4	16.1	21.7	43.3	16.3	22.2	27.5	17.1	16.2	25.1	6.4	15.8	15.7	31.5	11.9	21.6	22.0	16.4	22.2	23.4	12.7	15.8	19.7	21.6	11.3	23.4	5.5	8.2	10.1	10.1	9.8	5.7	6.4	10.1	11.7	7.9	14.3	19.7	13.2	6.2	7.0	11.8	6.5	7.7	9.9	9.0	13.1	10.4	12.0	7.9	11.0	12.2	12.6	8.5	8.4	5.4	5.6	13.0	14.3	10.4	6.4	7.3	15.9	14.8	5.6	9.2	16.3	17.6	11.2	18.6	9.2	11.6	11.6	9.1	7.1	8.3	10.2	7.5	8.1	4.1	10.2	16.2	13.8	18.4	14.7	8.3	10.2	8.8	8.0	6.0	13.3	12.7	16.2	13.1	18.7	19.5	17.7	15.6	13.5	22.2	21.6	18.6	1.5	19.7	15.8	23.4	18.3	11.3	20.1	21.0	26.8	20.8	17.2	15.3	18.6	17.5	17.7	15.8
XPC	"RAD4, XPCC"	ENSG00000154767	"XPC complex subunit, DNA damage recognition and repair factor"	Q01831	3	14145147-14178783	"Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease mutation, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009932, HPA035707, HPA069673"	Supported		Enhanced	"Nucleoplasm,Plasma membrane"				Nucleoplasm	"Plasma membrane"	"CAB009932: AB_2241587, HPA035707: , HPA069673: "	"unprognostic (7.46e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.50e-2)"	"unprognostic (3.01e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.54e-2)"	"unprognostic (1.97e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.50e-1)"	"unprognostic (7.13e-3)"	"unprognostic (4.39e-2)"	"unprognostic (2.07e-1)"	"prognostic favourable (4.14e-7)"	"unprognostic (1.59e-1)"	"unprognostic (7.88e-2)"	"unprognostic (7.62e-2)"	"prognostic favourable (2.46e-4)"	20.2	17.1	14.2	24.0	30.2	8.4	21.4	16.1	19.3	22.3	18.9	20.8	27.5	18.0	24.6	18.3	16.9	24.9	25.1	12.4	16.2	14.4	24.6	23.4	19.9	21.1	33.4	15.2	35.0	20.9	35.4	26.7	28.0	22.1	20.9	15.9	16.7	17.6	30.3	22.4	30.5	23.6	17.7	22.6	23.3	15.9	12.9	30.6	18.5	25.7	12.4	20.8	22.4	22.3	10.9	7.0	34.6	8.8	8.8	12.2	6.1	4.4	11.5	13.0	8.3	19.5	13.5	44.0	11.1	32.0	10.8	8.4	4.2	5.4	15.0	4.9	13.5	5.6	8.5	17.8	8.9	6.0	7.3	7.9	12.2	7.7	17.3	5.9	15.1	19.1	21.1	14.3	28.8	12.8	10.9	8.1	12.0	9.4	4.9	5.7	7.7	7.8	6.2	5.9	12.0	13.6	13.4	2.8	10.1	12.1	10.1	8.0	10.6	4.8	20.0	4.2	11.4	6.3	5.1	18.7	13.6	8.9	10.0	7.0	15.1	12.0	8.2	9.4	9.8	6.3	9.6	10.7	11.2	9.6	7.0	10.9	12.2	8.7	34.6	8.8	8.8	6.7	9.2	6.1	14.2	30.2	16.1	19.3	16.2	14.4	33.4	15.2	22.1	30.6
ZFHX3	"ATBF1, ZNF927"	ENSG00000140836	"Zinc finger homeobox 3"	Q15911	16	72782885-73891871	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Myogenesis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"NK-cell: 2.5"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA059353	Uncertain									"HPA059353: "	"prognostic unfavourable (1.55e-4)"	"unprognostic (3.57e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.03e-2)"	"unprognostic (2.81e-2)"	"unprognostic (3.12e-1)"	"unprognostic (4.24e-2)"	"unprognostic (6.36e-2)"	"unprognostic (9.94e-3)"	"unprognostic (2.85e-1)"	"unprognostic (1.06e-1)"	"unprognostic (4.16e-2)"	"prognostic favourable (1.37e-5)"	"unprognostic (6.76e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.15e-2)"	7.9	6.0	2.5	2.3	4.6	1.1	11.3	1.5	4.1	7.5	7.7	5.4	14.5	2.0	7.4	7.3	4.5	4.9	18.2	4.9	4.3	4.8	4.4	6.5	6.1	1.4	4.0	2.6	4.4	5.7	23.8	6.3	8.1	5.5	12.0	3.5	10.5	5.0	19.5	16.9	3.6	3.6	15.5	9.7	3.9	5.0	2.3	5.2	0.5	10.8	4.0	1.0	16.7	14.7	0.8	1.0	0.2	1.6	2.5	0.1	0.2	4.4	7.8	12.7	10.5	4.7	6.0	13.1	3.4	3.7	2.1	2.4	8.8	2.5	1.9	5.9	6.3	3.1	8.0	4.0	3.0	7.7	1.9	0.3	10.6	12.6	4.4	1.3	3.2	2.2	2.4	6.3	5.7	4.0	0.9	0.5	5.4	9.1	0.4	2.6	2.2	1.3	5.8	3.4	0.6	3.5	7.4	9.5	3.4	5.9	1.8	4.2	2.6	0.6	8.7	5.3	6.3	5.6	4.4	4.9	1.6	1.3	2.5	1.2	4.0	0.2	1.6	0.2	0.1	0.9	0.1	0.5	0.0	0.0	0.7	0.8	0.0	0.1	0.2	2.5	1.1	1.0	0.1	0.2	2.5	4.6	1.5	4.1	4.3	4.8	4.0	2.6	5.5	5.2