Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"
ACMSD		ENSG00000153086	"Aminocarboxymuconate semialdehyde decarboxylase"	Q8TDX5	2	134838547-134902034	"Enzymes, Predicted intracellular proteins"		"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	21	"kidney: 44.8;liver: 64.1"	"Cell line enriched"	"Detected in some"	22	"RPTEC TERT1: 24.2"	"Group enriched"	"Detected in some"	23	"liver cancer: 21.2;renal cancer: 19.8"	"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"							"HPA010533, HPA011179"	Enhanced						11000			"HPA010533: AB_1844517, HPA011179: AB_1844516"	"unprognostic (1.06e-2)"	"unprognostic (5.30e-2)"	"unprognostic (1.40e-1)"	"unprognostic (7.50e-2)"	"unprognostic (3.79e-2)"	"unprognostic (1.36e-2)"	"unprognostic (4.40e-3)"	"unprognostic (1.15e-1)"	"unprognostic (5.35e-4)"	"unprognostic (7.60e-2)"	"unprognostic (5.17e-2)"	"unprognostic (2.44e-3)"	"prognostic favourable (2.39e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.70e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.65e-5)"	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.2	0.0	0.0	2.5	0.0	0.0	0.0	44.8	64.1	0.1	0.0	0.0	0.0	0.1	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.5	1.4	0.9	0.6	0.2	1.7	0.5	0.3	0.1	0.4	0.3	0.0	0.0	0.2	0.5	0.0	0.0	0.0	0.3	0.0	0.9	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.3	0.2	0.7	0.0	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.3	0.6	0.2	1.0	0.4	0.1	0.5	0.2	24.2	0.3	0.9	0.3	0.1	0.2	0.4	0.2	0.6	0.8	0.0	0.3	0.2	0.7	0.1	0.1	0.4	0.1	0.2	0.6	0.0	0.6	0.9	0.9	0.5	0.4	1.5	0.9	1.3	0.9	1.1	1.7	0.9	0.4	0.2	0.5	1.4	0.8	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
ACO1	"IREB1, IREBP, IRP1"	ENSG00000122729	"Aconitase 1"	P21399	9	32384603-32454769	"Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	"Lyase, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 80.9"	"Cell line enhanced"	"Detected in many"		"ASC diff: 52.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019371, HPA024157"	Enhanced		Supported	Mitochondria,Cytosol			8000000	"Mitochondria, Cytosol"		"HPA019371: AB_1844519, HPA024157: AB_1844520"	"unprognostic (2.11e-1)"	"unprognostic (5.61e-2)"	"unprognostic (8.38e-2)"	"unprognostic (9.12e-2)"	"unprognostic (2.63e-1)"	"unprognostic (3.12e-2)"	"unprognostic (4.25e-3)"	"unprognostic (2.61e-2)"	"unprognostic (1.37e-1)"	"unprognostic (1.19e-1)"	"unprognostic (2.55e-1)"	"unprognostic (3.08e-1)"	"prognostic favourable (5.73e-5)"	"unprognostic (2.54e-1)"	"unprognostic (6.58e-2)"	"unprognostic (1.65e-1)"	"unprognostic (3.23e-2)"	41.4	27.2	9.6	7.1	9.4	1.5	30.1	8.9	8.1	9.3	19.7	6.2	6.4	21.9	12.8	14.6	12.8	7.2	8.9	15.1	6.5	7.6	40.5	80.9	9.2	9.4	6.1	6.2	14.1	27.9	8.9	8.7	11.3	7.7	10.7	9.8	11.7	11.7	9.5	11.2	5.5	28.4	14.5	6.0	6.4	13.5	11.4	5.9	6.0	18.4	7.2	5.1	13.9	11.7	4.7	7.1	21.4	8.8	4.7	7.4	6.2	9.4	8.7	6.7	10.6	52.5	28.5	3.0	17.9	44.1	8.2	6.5	9.1	2.9	1.9	5.7	18.7	1.3	13.3	17.1	16.6	6.0	3.6	13.8	9.4	9.9	26.4	1.3	5.6	24.8	5.3	21.2	15.0	21.3	4.9	4.1	23.4	2.4	7.3	6.6	7.0	9.2	5.7	10.0	1.9	31.4	8.7	0.8	2.8	18.6	0.7	1.9	4.3	3.4	23.0	30.1	10.2	10.0	4.6	2.0	3.8	3.7	21.0	4.6	2.6	21.4	8.7	2.4	7.4	8.8	6.4	4.7	5.2	5.7	7.1	4.2	6.8	7.0	1.0	4.7	7.2	3.4	2.8	6.2	9.6	9.4	8.9	8.1	6.5	7.6	6.1	6.2	7.7	5.9
ACO2	ACONM	ENSG00000100412	"Aconitase 2"	Q99798	22	41469125-41528989	"Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	Lyase	"Disease mutation, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 121.0;skeletal muscle: 157.9"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001097	Enhanced	Approved	Approved	Mitochondria			4000000	Mitochondria		"HPA001097: AB_1078092"	"unprognostic (1.95e-1)"	"unprognostic (2.50e-2)"	"unprognostic (2.35e-2)"	"unprognostic (3.06e-2)"	"unprognostic (6.51e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.99e-2)"	"unprognostic (6.54e-2)"	"unprognostic (1.20e-2)"	"unprognostic (7.32e-2)"	"unprognostic (1.64e-2)"	"unprognostic (6.07e-2)"	"prognostic favourable (0.00e+0)"	"unprognostic (1.46e-2)"	"unprognostic (9.60e-2)"	"unprognostic (6.45e-2)"	"unprognostic (1.12e-2)"	22.8	18.5	41.4	11.1	38.2	9.8	12.2	21.0	43.5	12.2	25.4	27.7	12.3	45.1	9.5	9.9	17.5	15.7	11.1	121.0	33.8	24.2	37.9	22.2	10.0	11.1	27.6	32.7	8.6	17.2	48.5	7.6	9.1	24.9	12.5	20.0	14.7	20.1	15.2	157.9	9.8	46.6	12.5	28.6	10.0	21.0	9.6	23.1	9.5	16.0	42.7	12.0	12.3	8.8	22.9	28.1	7.3	36.6	15.8	16.4	19.4	16.1	18.8	18.9	39.0	32.6	21.3	26.5	14.9	18.8	25.1	23.5	27.7	21.1	37.1	24.4	22.1	37.1	35.1	27.2	13.2	24.5	25.0	18.0	26.3	29.4	28.5	47.9	27.6	37.8	21.9	26.0	27.7	24.8	23.2	40.5	19.7	30.3	24.4	16.2	12.9	37.7	33.2	13.0	51.4	32.3	32.1	13.6	11.6	36.6	43.3	27.6	25.1	25.6	17.6	21.4	24.0	19.5	16.3	24.1	29.9	25.9	34.6	20.9	23.1	4.5	21.1	7.3	14.7	31.3	14.0	22.9	12.5	15.8	28.1	20.2	14.2	14.6	5.3	15.8	36.6	11.2	16.4	19.4	41.4	38.2	21.0	43.5	33.8	24.2	27.6	32.7	24.9	23.1
ACOD1	"CAD, IRG1"	ENSG00000102794	"Aconitate decarboxylase 1"	A6NK06	13	76948497-76958642	"Enzymes, Predicted intracellular proteins"	"Immunity, Inflammatory response, Innate immunity"	"Antimicrobial, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"liver: 3.0;lymphoid tissue: 5.8"	"Group enriched"	"Detected in some"	6	"PC-3: 1.1;U-87 MG: 3.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA040143	Uncertain									"HPA040143: AB_10793916"	"unprognostic (2.39e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.37e-1)"			"unprognostic (3.54e-2)"		"unprognostic (3.09e-1)"	"unprognostic (8.30e-2)"	"unprognostic (4.30e-2)"			"unprognostic (1.64e-5)"	"unprognostic (7.70e-2)"	"unprognostic (3.68e-2)"		"unprognostic (6.51e-3)"	1.4	0.1	0.0	5.8	0.0	0.6	0.0	0.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	1.4	0.0	0.1	0.1	0.1	0.0	0.0	0.3	3.0	1.1	4.3	0.0	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.8	0.8	0.3	0.0	0.6	0.0	0.0	0.1	0.5	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.0	3.4	0.0	0.0	0.0	0.7	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0
ADCY1	"AC1, DFNB44"	ENSG00000164742	"Adenylate cyclase 1"	Q08828	7	45574140-45723116	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Biological rhythms, cAMP biosynthesis"	"Calmodulin-binding, Lyase"	"Cancer-related genes, Deafness, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 29.0"	"Cell line enhanced"	"Detected in many"		"hTERT-HME1: 15.0;SCLC-21H: 9.1;SH-SY5Y: 17.3;SK-MEL-30: 19.9;WM-115: 11.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018364, HPA068274"	Uncertain		Approved	Mitochondria				Mitochondria		"CAB018364: AB_2223098, HPA068274: "	"unprognostic (9.41e-3)"	"unprognostic (7.30e-4)"	"unprognostic (9.31e-2)"	"unprognostic (2.98e-1)"	"unprognostic (4.18e-2)"	"unprognostic (3.07e-3)"	"unprognostic (1.32e-1)"	"unprognostic (7.31e-2)"	"unprognostic (1.64e-3)"	"unprognostic (2.89e-1)"	"unprognostic (7.73e-3)"	"unprognostic (1.54e-1)"	"unprognostic (4.74e-6)"	"unprognostic (2.49e-1)"	"unprognostic (7.65e-3)"	"unprognostic (2.87e-1)"	"unprognostic (2.23e-1)"	2.8	2.8	11.5	0.7	11.7	0.4	6.8	22.7	29.0	7.8	0.9	2.0	0.0	0.7	2.7	1.1	1.2	2.4	1.2	4.0	11.6	4.0	1.8	9.6	1.0	0.8	5.8	13.4	1.2	3.6	1.0	1.5	0.9	6.2	4.1	1.0	5.0	0.8	2.1	9.2	0.6	0.7	1.6	2.2	1.0	1.8	3.9	1.2	0.0	3.0	0.2	0.8	1.0	1.5	0.5	0.4	0.6	0.1	0.0	0.2	0.0	0.5	3.8	1.4	2.2	2.8	0.0	2.7	0.1	0.0	0.5	0.2	0.4	0.0	0.0	0.2	0.1	1.2	2.5	0.1	0.0	6.9	1.8	0.0	0.0	0.3	0.0	0.1	0.0	3.4	1.9	0.3	15.0	0.1	0.2	4.6	0.2	4.6	0.0	0.0	5.6	0.0	0.0	0.0	7.5	0.0	3.7	9.1	17.3	1.4	0.0	19.9	1.3	2.3	0.0	0.4	2.9	0.3	2.3	0.0	0.0	0.0	0.0	0.0	11.3	0.4	0.1	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.4	0.2	0.2	0.0	0.6	0.0	0.0	0.0	0.0	0.0	11.5	11.7	22.7	29.0	11.6	4.0	5.8	13.4	6.2	1.2
ADCY10	"HCA2, RP1-313L4.2, SAC, SACI, Sacy"	ENSG00000143199	"Adenylate cyclase 10"	Q96PN6	1	167809388-167914215	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	16	"liver: 14.9;testis: 38.6"	"Cell line enhanced"	"Detected in some"		"BEWO: 2.6;T-47d: 4.9"	"Cancer enhanced"	"Detected in single"		"liver cancer: 0.7"	"Region enriched"	"Detected in single"	5	"cerebellum: 1.6"	"Cell type enhanced"	"Detected in single"		"neutrophil: 1.4"	"Low lineage specificity"	"Detected in single"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA015243, HPA017749"	Approved									"HPA015243: AB_1856540, HPA017749: AB_1856541"	"unprognostic (1.20e-1)"	"unprognostic (2.53e-1)"	"unprognostic (1.95e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.65e-1)"	"unprognostic (5.35e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.63e-1)"	"unprognostic (3.65e-1)"	"unprognostic (4.43e-2)"	"unprognostic (7.83e-5)"	"unprognostic (5.86e-7)"	"unprognostic (4.73e-2)"	"unprognostic (1.33e-1)"	"unprognostic (7.83e-2)"	"unprognostic (2.59e-1)"	0.1	0.1	0.2	0.1	0.3	0.0	1.3	1.6	0.3	0.1	0.1	0.1	0.1	0.3	0.1	0.1	0.1	0.0	0.1	0.1	0.3	0.2	0.3	14.9	0.1	0.1	0.2	0.3	0.1	0.4	0.0	0.1	0.1	0.1	0.2	0.2	0.1	0.7	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	38.6	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.0	1.4	0.6	0.0	0.3	0.4	0.3	0.1	0.1	0.2	0.6	0.5	2.6	0.1	1.0	0.3	1.1	1.6	0.1	0.2	0.3	0.0	0.0	1.1	0.1	0.2	0.4	1.6	0.5	0.3	0.7	0.1	0.0	0.0	0.1	1.8	0.8	0.6	0.0	1.2	0.1	0.1	0.0	0.5	0.8	1.0	0.0	0.1	0.0	0.3	1.2	0.0	0.4	0.0	0.0	0.0	0.5	4.9	0.8	0.1	0.2	0.0	0.2	0.1	1.2	0.6	0.8	0.7	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.6	0.0	0.0	0.4	0.2	0.3	1.6	0.3	0.3	0.2	0.2	0.3	0.1	0.1
ADCY2	"AC2, HBAC2, KIAA1060"	ENSG00000078295	"Adenylate cyclase 2"	Q08462	5	7396208-7830081	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"brain: 35.9;skeletal muscle: 58.6"	"Group enriched"	"Detected in some"	7	"AF22: 9.2;NTERA-2: 7.0;SK-MEL-30: 7.7"	"Cancer enhanced"	"Detected in some"		"glioma: 4.9"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB031482, HPA038015, HPA038483"	Approved									"CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799"	"unprognostic (6.48e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.49e-1)"	"unprognostic (5.65e-2)"	"unprognostic (3.77e-1)"	"unprognostic (4.03e-4)"	"unprognostic (1.94e-2)"	"unprognostic (1.60e-2)"	"unprognostic (2.20e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.67e-2)"	"unprognostic (7.68e-2)"	"unprognostic (1.09e-5)"	"unprognostic (1.05e-1)"	"unprognostic (7.33e-3)"	"unprognostic (4.90e-2)"	"unprognostic (3.92e-3)"	1.8	3.3	16.8	1.3	14.5	1.2	2.8	6.6	35.9	4.9	1.9	6.7	0.7	1.9	3.9	1.7	4.0	4.1	2.1	1.2	14.5	9.4	1.2	1.1	1.3	1.1	12.8	10.0	5.1	1.9	1.0	5.1	1.8	11.3	6.2	1.6	2.0	1.5	5.1	58.6	6.3	1.8	4.3	12.5	1.2	2.6	3.6	5.4	0.0	1.1	5.1	1.2	1.9	2.1	0.9	0.4	1.5	0.4	0.3	0.6	0.0	0.0	0.0	9.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	7.0	0.0	0.1	1.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	7.7	0.3	0.0	0.0	0.2	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.9	0.4	0.1	0.4	0.2	0.4	0.5	0.3	0.3	0.1	0.9	0.4	0.6	1.5	0.3	0.3	0.4	0.2	0.0	16.8	14.5	6.6	22.5	14.5	9.4	12.8	10.0	11.3	5.4
ADCY3	AC3	ENSG00000138031	"Adenylate cyclase 3"	O60266	2	24819169-24919839	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis, Olfaction, Sensory transduction"	"Calmodulin-binding, Lyase"	Obesity	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB010223	Approved									"CAB010223: AB_630839"	"unprognostic (3.05e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.91e-2)"	"unprognostic (1.39e-3)"	"unprognostic (5.01e-2)"	"unprognostic (7.66e-2)"	"unprognostic (1.28e-1)"	"unprognostic (6.06e-2)"	"unprognostic (8.43e-2)"	"unprognostic (6.89e-2)"	"unprognostic (8.22e-3)"	"unprognostic (2.52e-1)"	"prognostic unfavourable (1.32e-9)"	"unprognostic (3.74e-2)"	"unprognostic (5.56e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.55e-3)"	35.8	8.2	14.4	11.7	26.0	13.2	41.2	15.0	21.7	22.5	15.1	16.5	6.5	7.6	23.3	15.6	17.4	21.4	18.2	18.2	13.7	13.1	9.5	4.6	15.3	13.7	29.6	14.1	29.5	7.7	15.4	16.2	58.6	16.3	15.1	11.7	11.3	8.7	24.9	7.9	14.8	12.3	25.1	12.4	11.7	9.8	11.3	18.2	4.3	14.4	13.9	12.8	13.5	24.2	7.2	11.0	3.2	1.8	1.1	3.1	1.2	28.0	19.3	6.3	10.6	32.0	25.5	12.2	14.1	20.7	12.3	11.3	15.6	9.7	9.8	3.2	20.6	20.6	15.4	19.2	8.6	22.3	20.5	16.0	21.2	2.0	24.3	9.1	10.1	21.3	16.3	12.3	18.7	11.3	8.0	17.2	7.2	20.1	8.8	2.1	6.8	8.4	15.6	32.9	20.3	5.3	16.8	10.2	7.5	17.6	21.0	12.1	5.4	7.6	10.8	21.6	15.5	12.5	21.2	17.9	41.6	38.3	7.0	14.4	13.4	3.2	1.8	0.0	0.6	1.8	0.3	6.4	1.4	0.5	11.0	7.2	0.7	0.6	0.0	1.1	0.4	10.1	3.1	1.2	14.4	26.0	15.0	21.7	13.7	13.1	29.6	14.1	16.3	18.2
ADCY4	AC4	ENSG00000129467	"Adenylate cyclase 4"	Q8NFM4	14	24318349-24335093	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"HUVEC TERT2: 9.7;TIME: 4.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in some"	4	"basophil: 5.0"	"Lineage enriched"	"Detected in many"	4	"granulocytes: 5.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005070, HPA048344"	Approved									"CAB005070: AB_2273639, HPA048344: "	"unprognostic (5.59e-2)"	"unprognostic (1.34e-1)"	"unprognostic (3.47e-4)"	"prognostic favourable (8.20e-4)"	"unprognostic (4.06e-1)"	"unprognostic (2.82e-3)"	"unprognostic (1.75e-4)"	"unprognostic (8.58e-2)"	"unprognostic (2.51e-2)"	"unprognostic (7.88e-2)"	"unprognostic (6.77e-2)"	"unprognostic (7.87e-2)"	"prognostic unfavourable (7.01e-4)"	"unprognostic (8.02e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	15.8	2.7	2.3	4.6	2.0	1.5	14.2	1.1	2.4	13.3	4.4	1.6	6.3	1.7	16.8	10.0	6.0	7.7	10.9	10.3	1.6	1.4	6.3	2.0	14.7	8.4	2.3	1.5	3.2	2.1	4.7	1.8	17.8	2.7	4.8	2.3	5.8	3.6	8.0	6.2	4.4	3.9	7.0	1.9	9.3	3.4	2.6	1.6	0.0	7.4	7.3	3.3	5.9	12.6	0.0	1.1	5.0	0.2	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.4	0.9	0.0	0.9	0.4	1.0	0.1	0.0	0.6	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.5	0.0	0.0	0.0	0.0	0.6	0.1	0.0	0.8	0.0	0.2	0.0	9.7	0.0	0.4	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	1.2	4.0	0.3	0.1	1.0	0.0	0.2	0.0	0.0	0.0	0.4	0.1	5.0	0.2	0.2	0.0	0.0	0.1	0.0	0.1	0.0	1.1	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	2.3	2.0	1.1	2.4	1.6	1.4	2.3	1.5	2.7	1.6
ADCY5	AC5	ENSG00000173175	"Adenylate cyclase 5"	O95622	3	123282296-123449758	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 69.9"	"Cell line enhanced"	"Detected in some"		"MCF7: 17.6;RPMI-8226: 3.1;RPTEC TERT1: 6.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enriched"	"Detected in many"	5	"basal ganglia: 347.3"	"Region enriched"	"Detected in all"	6	"basal ganglia: 205.1"	"HPA017730, HPA077682"	Uncertain		Enhanced	"Intermediate filaments"				"Intermediate filaments"		"HPA017730: AB_1844595, HPA077682: "	"unprognostic (3.55e-2)"	"unprognostic (1.01e-3)"	"unprognostic (7.61e-3)"	"unprognostic (2.05e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.26e-2)"	"unprognostic (1.48e-1)"	"unprognostic (7.61e-2)"	"unprognostic (2.49e-2)"	"unprognostic (2.34e-1)"	"unprognostic (7.27e-3)"	"unprognostic (2.64e-2)"	"prognostic favourable (7.46e-6)"	"unprognostic (1.81e-2)"	"unprognostic (5.65e-2)"	"unprognostic (3.19e-2)"	"unprognostic (5.97e-4)"	13.3	3.0	12.5	3.7	32.0	0.6	9.3	2.6	14.4	4.5	11.7	10.4	3.1	4.2	6.2	4.4	13.8	5.3	7.3	69.9	10.4	8.3	5.3	2.4	2.6	2.0	15.0	8.6	10.1	5.7	1.1	7.7	4.8	9.7	13.8	4.6	4.6	3.1	16.3	2.2	1.1	4.8	13.5	8.8	4.7	9.6	5.9	16.0	0.0	1.0	0.2	2.6	9.5	8.5	0.0	0.0	0.0	0.0	0.0	0.5	0.1	0.0	0.6	1.5	0.1	0.1	0.1	0.4	0.0	0.0	0.4	0.1	0.1	0.1	0.0	0.3	0.2	0.5	0.8	0.0	0.0	0.1	1.0	0.0	0.2	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.1	0.1	17.6	0.0	0.0	1.0	0.1	0.0	0.4	3.1	6.3	0.6	2.2	2.0	0.0	0.6	0.1	0.0	0.1	0.0	0.1	1.5	0.1	0.3	0.2	0.7	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.5	0.1	12.5	32.0	2.6	14.4	10.4	8.3	15.0	8.6	9.7	16.0
ADCY6	AC6	ENSG00000174233	"Adenylate cyclase 6"	O43306	12	48766194-48789037	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"SK-BR-3: 30.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB018365	Approved		Approved	"Golgi apparatus"				"Golgi apparatus"		"CAB018365: AB_2257941"	"unprognostic (1.18e-2)"	"unprognostic (2.20e-2)"	"unprognostic (6.89e-2)"	"unprognostic (1.31e-1)"	"unprognostic (3.84e-2)"	"unprognostic (3.68e-2)"	"prognostic unfavourable (8.23e-4)"	"unprognostic (1.55e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.29e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.64e-2)"	"unprognostic (5.06e-3)"	"unprognostic (5.10e-3)"	"unprognostic (1.09e-1)"	"unprognostic (3.09e-1)"	"unprognostic (2.48e-2)"	25.9	9.6	14.1	12.4	7.5	0.8	19.7	15.0	17.0	9.8	15.2	5.5	16.2	12.3	13.2	12.8	6.2	9.5	17.6	37.5	9.9	8.3	11.3	5.6	8.5	4.7	5.6	11.0	14.6	17.4	15.8	9.1	9.5	8.9	11.1	12.6	11.8	19.9	12.0	7.3	10.2	13.9	9.1	4.7	2.9	13.5	4.0	5.5	0.6	11.1	6.8	3.8	7.8	14.9	1.8	0.4	1.4	0.4	0.5	0.4	0.5	5.9	11.5	13.3	8.3	14.0	7.0	14.4	7.3	7.4	8.9	6.2	20.4	20.0	0.0	16.8	6.3	4.8	3.8	4.9	3.2	0.0	5.9	5.4	15.7	3.7	8.0	0.0	4.5	8.9	6.0	7.4	2.7	8.1	0.7	2.0	6.5	10.3	0.0	0.2	4.5	5.4	1.9	5.1	3.2	10.0	18.5	2.0	8.2	7.5	30.1	6.5	23.5	1.4	9.2	8.4	6.0	4.4	3.2	3.1	1.5	0.2	7.6	0.0	3.8	1.4	0.4	0.4	0.3	0.2	0.2	1.1	0.3	0.2	0.3	1.8	0.4	0.3	0.9	0.5	0.4	0.4	0.2	0.5	14.1	7.5	15.0	17.0	9.9	8.3	5.6	11.0	8.9	5.5
ADCY7	"AC7, KIAA0037"	ENSG00000121281	"Adenylate cyclase 7"	P51828	16	50246137-50318135	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"HEL: 22.9;HMC-1: 63.9;RPMI-8226: 31.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA041218, HPA048241"	Uncertain		Approved	Cytosol				Cytosol		"HPA041218: , HPA048241: "	"unprognostic (1.98e-1)"	"prognostic unfavourable (5.31e-4)"	"unprognostic (1.24e-1)"	"unprognostic (1.78e-1)"	"unprognostic (3.77e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.90e-2)"	"unprognostic (7.75e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.56e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.18e-1)"	"unprognostic (5.59e-3)"	"unprognostic (7.34e-2)"	"unprognostic (2.15e-3)"	"unprognostic (2.18e-1)"	"unprognostic (9.52e-4)"	6.3	4.3	7.0	17.4	9.7	14.9	3.9	1.2	5.2	3.7	5.0	9.8	0.8	2.8	3.7	4.8	13.2	5.3	6.9	7.3	5.3	4.2	3.3	3.6	16.4	16.5	8.8	4.4	17.1	3.7	1.0	3.4	9.7	8.6	3.5	5.9	6.2	6.5	1.6	1.8	7.9	10.4	5.0	12.3	26.9	4.9	2.1	9.2	21.8	3.7	3.1	26.0	6.6	6.1	3.6	12.5	6.5	16.7	8.4	7.0	5.0	3.9	5.4	0.2	0.7	0.5	7.0	0.5	2.8	1.3	2.1	2.0	5.1	8.2	1.6	7.4	11.1	14.3	5.6	2.4	2.7	15.1	2.0	22.9	4.1	1.4	6.4	4.3	63.9	3.7	2.3	1.6	2.5	0.6	8.3	3.2	3.0	2.3	1.6	10.2	0.9	7.7	1.6	2.1	31.7	1.5	0.3	0.9	2.6	1.5	0.6	1.3	0.1	12.8	5.0	0.3	7.5	0.8	0.7	0.3	0.1	3.5	2.4	9.3	1.0	6.5	7.8	2.9	7.0	11.7	5.1	3.2	2.8	5.0	12.5	3.6	2.6	3.7	4.4	8.4	16.7	6.5	3.9	5.0	7.0	9.7	1.2	5.2	5.3	4.2	8.8	4.4	8.6	9.2
ADCY8	"AC8, ADCY3, HBAC1"	ENSG00000155897	"Adenylate cyclase 8"	P40145	8	130780301-131042426	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 9.6;epididymis: 27.8"	"Group enriched"	"Detected in some"	5	"U-138 MG: 13.5;U-87 MG: 26.2"	"Group enriched"	"Detected in some"	5	"glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018652, HPA024291"	Supported									"CAB018652: AB_633654, HPA024291: AB_1844597"	"unprognostic (5.59e-3)"				"unprognostic (3.10e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.09e-1)"	"unprognostic (2.78e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.05e-1)"	"unprognostic (8.22e-3)"	"unprognostic (4.91e-2)"	"unprognostic (7.39e-3)"	"unprognostic (1.92e-1)"	"unprognostic (2.44e-2)"	"unprognostic (6.67e-2)"		0.2	0.2	8.2	0.2	5.1	0.2	0.9	5.3	9.6	0.8	0.2	1.2	1.4	0.2	0.3	27.8	0.2	4.8	0.2	0.3	6.4	6.2	0.5	0.2	1.6	0.2	7.8	0.6	0.3	0.2	0.2	0.0	0.2	5.7	0.2	0.2	0.0	2.8	2.0	0.2	1.5	0.2	0.9	5.0	0.2	0.3	0.7	1.1	0.0	0.2	0.0	0.2	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	3.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	13.5	0.3	0.0	0.0	0.0	0.0	0.0	26.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.2	5.1	5.3	5.0	6.4	6.2	7.8	0.6	5.7	1.1
ADCY9	AC9	ENSG00000162104	"Adenylate cyclase 9"	O60503	16	3953387-4116185	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skeletal muscle: 36.4"	"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 23.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041328, HPA044225"	Approved		Approved	Cytosol				Cytosol		"HPA041328: , HPA044225: "	"unprognostic (1.78e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.57e-1)"	"prognostic unfavourable (2.55e-5)"	"unprognostic (6.62e-2)"	"unprognostic (1.30e-2)"	"unprognostic (2.52e-1)"	"unprognostic (3.61e-2)"	"unprognostic (6.93e-2)"	"unprognostic (4.76e-3)"	"unprognostic (5.40e-2)"	"unprognostic (1.37e-1)"	"prognostic favourable (5.24e-8)"	"unprognostic (1.19e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.55e-2)"	5.2	4.8	7.1	3.2	10.9	0.9	5.4	8.5	9.6	7.0	6.4	4.1	4.4	6.5	6.5	4.4	6.8	7.7	6.5	13.3	6.2	3.0	8.0	9.6	11.1	2.5	3.0	6.2	9.4	12.5	12.3	5.8	7.8	7.7	3.6	5.5	9.0	10.1	5.0	36.4	4.4	10.9	6.3	2.2	3.2	5.5	4.4	3.4	0.7	21.8	7.7	3.0	7.9	4.8	0.1	1.0	3.2	1.5	1.0	1.9	0.9	4.8	7.5	2.3	4.2	8.2	10.1	3.4	8.6	9.0	4.8	3.9	6.2	4.3	0.0	13.3	23.6	4.8	8.9	5.4	3.3	6.0	8.6	0.2	17.2	11.9	8.9	0.6	3.9	10.7	8.3	5.6	3.0	3.2	2.6	0.0	4.9	8.9	0.0	2.5	4.1	4.1	7.7	10.9	0.2	1.7	1.3	5.2	2.3	6.7	7.9	5.8	20.1	8.7	3.0	9.7	2.7	9.4	3.7	1.9	1.1	1.0	2.1	2.6	3.7	3.2	1.5	1.0	1.9	1.5	1.7	0.0	0.6	0.6	0.1	0.1	0.1	1.1	0.3	1.0	0.0	1.0	0.0	0.9	7.1	10.9	8.5	9.6	6.2	3.0	3.0	6.2	7.7	3.4
ADSL		ENSG00000239900	"Adenylosuccinate lyase"	P30566	22	40346500-40390463	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Purine biosynthesis"	Lyase	"Disease mutation, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 79.0"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000525, CAB019285"	Enhanced		Enhanced	Cytosol			180000	Cytosol		"CAB019285: , HPA000525: AB_1078106"	"unprognostic (2.80e-1)"	"unprognostic (2.12e-1)"	"prognostic favourable (2.38e-4)"	"unprognostic (2.64e-1)"	"unprognostic (1.02e-1)"	"unprognostic (6.87e-3)"	"prognostic unfavourable (5.81e-8)"	"unprognostic (1.35e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.99e-1)"	"unprognostic (6.28e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.99e-2)"	"unprognostic (8.43e-2)"	"unprognostic (2.70e-1)"	"unprognostic (4.06e-1)"	"unprognostic (1.44e-2)"	9.3	11.6	5.0	13.7	8.5	11.2	9.0	6.8	10.1	7.9	9.5	7.3	4.4	6.0	10.8	9.4	9.7	9.0	6.9	14.6	4.5	4.7	12.0	17.3	6.8	17.6	4.9	4.9	10.5	21.8	5.4	9.1	9.5	5.1	7.1	9.7	9.2	14.7	6.4	79.0	6.2	9.4	10.7	4.9	14.5	9.6	10.9	4.4	18.8	8.4	23.6	15.5	9.5	7.4	15.3	28.8	11.0	22.7	19.8	34.0	24.6	21.0	24.9	21.4	30.5	14.5	20.4	24.8	19.3	19.1	41.8	32.0	41.1	12.4	61.3	16.4	22.3	15.9	47.7	31.0	43.0	16.3	44.9	27.8	28.1	37.8	30.3	90.4	23.4	21.9	17.6	36.7	39.0	30.9	32.8	26.9	31.2	23.5	27.9	32.3	34.9	26.6	42.6	45.0	43.5	26.9	16.7	13.8	13.6	23.0	12.7	36.5	17.6	28.6	20.4	22.4	41.5	19.7	36.9	25.6	44.6	47.0	18.6	33.6	21.8	11.0	19.3	7.8	16.2	22.7	22.8	15.3	34.0	21.7	28.8	14.9	27.0	20.8	1.9	19.8	20.2	14.9	34.0	24.6	5.0	8.5	6.8	10.1	4.5	4.7	4.9	4.9	5.1	4.4
ALAD	"ALADH, PBGS"	ENSG00000148218	"Aminolevulinate dehydratase"	P13716	9	113386317-113401333	"Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	"Allosteric enzyme, Lyase"	"Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 84.2"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021023, HPA022124"	Enhanced						44000000			"HPA021023: AB_1844716, HPA022124: AB_1844717"	"unprognostic (2.75e-1)"	"unprognostic (6.26e-2)"	"prognostic unfavourable (7.33e-5)"	"prognostic favourable (5.64e-4)"	"unprognostic (4.16e-2)"	"unprognostic (9.49e-2)"	"prognostic favourable (8.80e-5)"	"unprognostic (2.87e-3)"	"unprognostic (3.49e-1)"	"unprognostic (2.95e-1)"	"unprognostic (1.62e-1)"	"unprognostic (3.31e-2)"	"prognostic favourable (1.65e-4)"	"unprognostic (1.75e-1)"	"unprognostic (1.22e-1)"	"unprognostic (3.40e-1)"	"unprognostic (1.31e-2)"	19.9	70.3	24.1	6.4	26.3	27.3	13.7	14.0	24.8	8.3	10.5	28.3	8.8	11.6	7.5	11.5	14.6	6.8	13.0	23.3	24.6	20.8	29.9	84.2	8.4	5.9	37.5	20.6	12.3	18.8	24.1	7.2	10.2	27.9	14.5	10.2	9.8	37.2	15.1	10.6	15.6	10.7	8.9	40.1	5.9	18.1	5.4	28.6	4.7	10.9	6.6	7.5	9.0	8.0	7.6	12.1	19.1	13.1	5.5	9.7	7.6	3.4	6.0	4.7	6.6	32.9	22.7	30.0	9.3	15.7	6.2	7.8	8.3	7.2	4.8	5.7	13.2	12.7	3.4	6.4	3.6	12.0	4.3	9.6	7.5	10.9	7.5	8.7	8.2	19.1	4.8	5.6	2.5	12.1	3.6	7.2	10.1	25.1	10.0	8.7	2.4	11.9	7.9	8.2	8.3	9.6	7.2	4.3	4.1	11.8	14.4	8.5	15.2	10.0	13.1	5.5	4.2	10.8	5.2	10.7	10.0	3.8	15.5	8.1	5.9	7.2	11.5	19.1	9.7	13.1	5.4	5.9	8.4	5.4	12.1	7.6	8.1	8.9	5.6	5.5	12.7	4.9	8.5	7.6	24.1	26.3	14.0	24.8	24.6	20.8	37.5	20.6	27.9	28.6
ALDOA		ENSG00000149925	"Aldolase, fructose-bisphosphate A"	P04075	16	30064164-30070457	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Glycolysis	Lyase	"Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	6	"skeletal muscle: 1296.2"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"HPA004177, CAB006252"	Enhanced		Supported	Cytosol			1200000000	Cytosol		"CAB006252: AB_437007, HPA004177: AB_1078128"	"unprognostic (2.63e-2)"	"unprognostic (3.22e-2)"	"unprognostic (6.80e-2)"	"unprognostic (1.33e-1)"	"unprognostic (6.74e-3)"	"unprognostic (4.28e-3)"	"prognostic unfavourable (5.79e-5)"	"prognostic unfavourable (7.32e-5)"	"unprognostic (1.68e-1)"	"unprognostic (1.81e-1)"	"unprognostic (2.30e-2)"	"unprognostic (1.57e-1)"	"unprognostic (1.81e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.19e-3)"	"unprognostic (4.48e-2)"	27.9	30.9	34.7	24.2	42.3	36.0	25.3	31.2	59.7	21.0	32.8	16.3	25.9	29.4	21.9	33.9	73.5	22.1	24.4	109.3	31.6	33.4	28.2	11.1	17.9	34.0	35.0	49.6	23.4	19.4	51.0	25.2	19.9	38.0	23.6	23.5	24.6	37.9	36.9	1296.2	28.4	21.5	30.1	22.7	17.4	24.4	9.2	18.9	18.5	26.6	189.8	29.0	36.8	27.7	61.1	142.9	165.7	166.3	50.5	93.2	217.0	138.7	104.6	31.5	101.2	48.3	55.1	100.7	84.0	87.6	85.7	107.2	73.9	107.0	94.6	137.8	84.8	106.0	63.1	183.2	62.9	41.6	83.0	77.4	83.9	163.2	75.4	112.5	83.1	75.5	64.7	96.2	64.7	63.1	66.6	62.5	90.8	197.9	68.4	93.0	78.3	88.2	102.1	50.6	211.5	106.7	79.0	63.1	44.4	52.4	221.1	78.4	94.0	76.3	75.0	126.6	50.5	69.0	90.8	123.5	84.3	86.6	235.6	109.3	99.9	106.7	164.0	130.3	70.2	156.8	79.1	61.1	76.8	72.5	142.9	55.5	73.8	70.3	165.7	50.5	166.3	53.8	93.2	217.0	34.7	42.3	31.2	59.7	31.6	33.4	35.0	49.6	38.0	18.9
ALDOA		ENSG00000285043	"Aldolase, fructose-bisphosphate A"	P04075	16	30053090-30070420	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	Glycolysis	Lyase	"Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"											"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"											HPA004177	Uncertain		Supported	Cytosol			1200000000	Cytosol		"HPA004177: AB_1078128"																		1.8	0.9	2.7	1.1	5.0	2.1	7.2	0.7	7.7	4.9	1.5	2.0	2.4	0.0	2.5	3.9	0.9	3.6	1.6	5.3	2.3		1.3	0.0	2.3	2.0	0.8	4.4	2.2	0.8	0.8	3.0	1.4	4.0	2.4	0.5	2.8	1.6	7.5	10.6	0.6	0.1	1.9	0.4	1.7	1.3	11.6	0.8	1.2	4.7	0.2	2.7	1.2	1.0	7.0	6.6	0.9	6.2	4.2	8.5	12.5	3.7	8.8	1.9	6.2	1.5	5.2	1.5	4.0	6.9	5.4	21.6	3.6	5.0	24.5	5.9	6.8	6.3	14.0	10.9	3.8	4.3	7.9	6.0	8.2	5.9	11.5	10.5	2.3	5.1	0.5	10.7	12.2	7.7	1.2	7.1	13.4	3.9	4.9	8.0	2.1	5.5	7.6	4.0	22.4	15.1	0.7	6.1	5.0	1.0	1.6	1.5	5.1	4.0	1.7	8.0	2.4	3.7	5.3	7.3	5.5	8.0	7.6	11.4	3.5	0.1	6.2	0.1	5.3	2.6	7.4	7.0	7.0	5.7	6.6	6.2	8.5	6.6	0.9	4.2	2.3	5.6	5.4	12.5										
ALDOB		ENSG00000136872	"Aldolase, fructose-bisphosphate B"	P05062	9	101420578-101435823	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Glycolysis	Lyase	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	30	"intestine: 804.1;kidney: 253.1;liver: 598.8"	"Cell line enhanced"	"Detected in some"		"BEWO: 14.1;NB-4: 13.2;RPMI-8226: 15.2;SH-SY5Y: 13.2"	"Cancer enriched"	"Detected in many"	31	"liver cancer: 1414.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"HPA002198, CAB020827"	Enhanced						930000000			"CAB020827: , HPA002198: AB_1078129"	"unprognostic (6.58e-3)"	"unprognostic (2.83e-1)"	"unprognostic (1.43e-3)"	"unprognostic (1.03e-1)"	"unprognostic (8.10e-2)"	"unprognostic (1.96e-2)"	"unprognostic (1.44e-3)"	"unprognostic (4.34e-2)"	"unprognostic (4.57e-2)"	"unprognostic (2.66e-1)"	"unprognostic (5.79e-2)"	"unprognostic (7.48e-2)"	"unprognostic (1.66e-2)"	"unprognostic (2.02e-1)"	"unprognostic (2.58e-1)"	"unprognostic (5.19e-2)"	"unprognostic (1.96e-2)"	0.1	0.1	0.1	0.6	0.1	0.0	0.1	0.1	0.2	0.1	334.5	0.2	0.2	145.9	0.2	0.6	0.1	0.1	5.7	0.1	0.1	0.1	253.1	598.8	0.1	0.1	0.1	0.1	0.1	18.3	0.0	0.4	0.1	0.4	0.1	0.0	0.2	0.2	0.1	0.1	0.1	804.1	0.1	0.1	0.2	1.5	0.3	0.1	0.2	0.2	0.2	0.1	0.1	0.1	0.0	0.0	0.0	0.1	0.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	14.1	0.0	0.0	0.0	0.0	0.3	0.0	2.9	1.4	0.0	0.4	0.0	0.0	0.0	0.3	0.0	1.3	0.0	0.4	0.0	3.5	0.3	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.0	0.0	0.2	13.2	0.2	0.0	0.2	3.1	15.2	0.0	0.0	2.5	13.2	1.5	0.0	0.0	0.0	0.1	0.7	0.0	0.7	5.3	0.2	0.4	0.2	1.6	0.0	1.1	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.4	0.1
ALDOC		ENSG00000109107	"Aldolase, fructose-bisphosphate C"	P09972	17	28573115-28577264	"Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	Glycolysis	Lyase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"brain: 166.7;heart muscle: 56.9"	"Cell line enhanced"	"Detected in many"		"RPMI-8226: 62.2;U-266/70: 42.9"	"Cancer enriched"	"Detected in all"	6	"glioma: 128.9"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003282, CAB020828, HPA067442"	Enhanced	Supported	Approved	"Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol"			280000000	"Nucleoplasm, Nucleoli fibrillar center"	"Vesicles, Cytosol"	"CAB020828: , HPA003282: AB_1078130, HPA067442: "	"unprognostic (2.90e-1)"	"unprognostic (4.45e-3)"	"unprognostic (5.69e-3)"	"unprognostic (1.43e-1)"	"unprognostic (3.56e-1)"	"prognostic unfavourable (9.80e-4)"	"unprognostic (1.03e-1)"	"unprognostic (1.70e-1)"	"unprognostic (1.30e-1)"	"unprognostic (6.03e-3)"	"unprognostic (3.90e-1)"	"unprognostic (3.24e-2)"	"prognostic unfavourable (1.29e-7)"	"unprognostic (1.28e-1)"	"unprognostic (2.00e-1)"	"unprognostic (2.74e-2)"	"unprognostic (1.23e-1)"	26.0	9.4	86.7	4.8	78.9	7.5	9.8	100.1	166.7	3.8	5.3	17.4	0.3	7.0	4.4	4.6	7.1	3.9	4.4	56.9	64.6	54.3	3.3	26.2	4.6	6.5	69.9	51.4	12.8	1.6	4.7	2.3	2.1	98.1	6.0	5.6	16.5	4.2	6.1	1.7	12.5	15.0	4.6	34.4	6.7	8.7	4.6	23.4	0.0	2.1	0.5	10.0	3.4	3.5	12.2	4.6	8.8	4.1	13.7	20.5	8.8	7.4	0.5	3.5	14.4	7.2	7.4	0.7	3.8	8.6	2.9	18.1	4.3	0.7	3.5	4.6	3.4	9.7	2.3	23.6	5.5	3.0	2.2	6.7	2.7	7.4	6.8	2.4	7.8	6.8	3.3	0.3	5.9	1.3	4.6	18.8	2.5	3.5	2.8	8.1	5.4	3.9	2.4	0.4	62.2	0.4	1.0	9.2	16.4	2.2	17.7	0.1	9.6	5.5	0.9	0.3	1.4	0.5	0.6	42.9	12.3	2.6	28.1	7.0	0.5	0.1	3.5	1.4	11.4	4.1	16.2	12.2	15.6	9.2	4.6	11.5	20.5	15.1	8.8	13.7	2.3	2.2	19.5	8.8	86.7	78.9	100.1	78.5	64.6	54.3	69.9	51.4	98.1	23.4
ALKBH1	"ABH, alkB, ALKBH, hABH"	ENSG00000100601	"AlkB homolog 1, histone H2A dioxygenase"	Q13686	14	77672404-77708020	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, RNA repair, Translation regulation"	"Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044087, HPA060061"	Approved		Supported	"Nucleoplasm,Endoplasmic reticulum"	"Intracellular and membrane"			Nucleoplasm	"Endoplasmic reticulum"	"HPA044087: , HPA060061: "	"unprognostic (1.92e-2)"	"unprognostic (8.38e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.37e-3)"	"unprognostic (3.41e-2)"	"unprognostic (5.03e-2)"	"unprognostic (3.74e-3)"	"unprognostic (7.45e-3)"	"unprognostic (2.68e-2)"	"unprognostic (3.95e-2)"	"unprognostic (5.05e-3)"	"unprognostic (2.16e-2)"	"prognostic favourable (1.80e-4)"	"unprognostic (1.65e-3)"	"unprognostic (1.46e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.44e-2)"	8.2	8.5	6.2	6.7	8.6	2.7	9.7	9.6	8.8	9.7	9.1	8.2	4.5	6.5	7.0	5.9	7.1	8.0	5.8	11.1	5.4	5.7	7.9	9.4	5.9	8.3	6.5	3.7	8.3	7.9	8.4	11.2	10.2	6.4	9.3	9.1	9.9	7.2	8.7	16.5	8.2	6.7	7.8	5.5	8.3	7.8	9.9	6.6	12.7	8.8	6.5	10.3	8.5	9.4	5.4	4.9	11.4	5.7	5.2	5.3	3.2	5.2	7.8	6.4	4.3	6.9	7.5	8.0	5.5	7.2	12.2	13.7	7.9	3.2	8.1	3.1	5.0	4.8	13.9	5.9	14.4	5.5	5.4	4.3	4.6	6.6	9.7	4.5	2.8	6.4	9.9	7.1	11.3	9.9	6.6	4.7	6.5	8.3	6.0	5.9	7.0	10.1	6.1	6.5	5.4	7.0	4.7	8.2	6.1	4.5	4.7	5.9	11.6	4.7	4.5	5.1	5.2	5.6	4.4	5.9	9.3	7.9	3.4	6.5	5.0	11.4	5.0	2.2	5.0	5.7	4.3	5.4	4.7	5.0	4.9	4.9	5.0	3.9	1.4	5.2	3.8	2.6	5.3	3.2	6.2	8.6	9.6	8.8	5.4	5.7	6.5	3.7	6.4	6.6
ALOXE3	"E-LOX, eLOX3"	ENSG00000179148	"Arachidonate lipoxygenase 3"	Q9BYJ1	17	8095900-8119047	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Dioxygenase, Isomerase, Lyase, Oxidoreductase"	"Disease mutation, Ichthyosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	11	"skin 1: 30.2"	"Cell line enhanced"	"Detected in some"		"A-431: 6.5;HBEC3-KT: 10.6;hTCEpi: 7.8;hTERT-HME1: 14.8;T-47d: 4.7"	"Cancer enhanced"	"Detected in some"		"head and neck cancer: 3.9"	"Group enriched"	"Detected in many"	8	"basal ganglia: 1.1;cerebellum: 1.4;cerebral cortex: 2.3;pons and medulla: 1.1"	"Group enriched"	"Detected in some"	5	"gdT-cell: 1.0;naive CD4 T-cell: 2.7"	"Lineage enriched"	"Detected in single"	28	"T-cells: 2.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA023120, HPA078597"	Enhanced		Approved	"Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"		"HPA023120: AB_10959300, HPA078597: "	"unprognostic (2.40e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.87e-3)"	"unprognostic (2.09e-4)"	"unprognostic (1.07e-2)"	"unprognostic (4.06e-2)"		"unprognostic (3.56e-4)"	"unprognostic (3.60e-1)"	"unprognostic (4.65e-2)"	"unprognostic (3.82e-2)"	"unprognostic (3.72e-1)"	"unprognostic (3.66e-5)"	"unprognostic (9.81e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.08e-2)"	"unprognostic (2.88e-2)"	0.1	0.0	0.1	0.1	1.1	0.0	1.6	1.4	2.3	1.2	0.1	0.1	0.1	0.0	0.1	0.1	0.3	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1	1.1	0.1	0.0	0.1	0.1	0.1	0.1	30.2	0.1	0.1	0.1	0.1	0.0	0.4	0.1	0.1	0.1	0.1	1.0	0.1	0.8	0.0	0.0	0.0	0.0	0.0	2.7	0.2	6.5	0.8	0.0	0.0	0.0	0.0	0.0	0.5	0.5	0.1	0.4	0.1	0.5	0.2	0.2	0.1	0.4	0.9	10.6	0.1	0.0	0.4	0.0	0.2	0.0	0.0	0.0	0.0	0.0	7.8	0.1	14.8	0.0	0.0	0.1	0.0	2.3	0.0	0.0	0.0	2.1	0.0	0.0	0.0	0.1	0.3	0.0	0.1	0.0	0.7	0.0	4.7	0.0	0.1	0.0	2.3	0.0	0.3	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	2.7	0.2	0.0	0.0	0.0	0.0	0.0	0.2	0.1	1.1	1.4	2.3	0.1	0.1	0.1	0.1	1.1	0.1
AMD1	SAMDC	ENSG00000123505	"Adenosylmethionine decarboxylase 1"	P17707	6	110874770-110895713	"Enzymes, Predicted intracellular proteins"	"Polyamine biosynthesis, Spermidine biosynthesis"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"prostate: 104.7"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			"HPA029281, HPA029282"	Approved		Approved	Nucleoplasm				Nucleoplasm		"HPA029281: AB_10600101, HPA029282: AB_10599965"	"prognostic unfavourable (3.87e-4)"	"unprognostic (4.68e-2)"	"unprognostic (1.85e-3)"	"unprognostic (1.01e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.05e-1)"	"prognostic unfavourable (1.91e-6)"	"unprognostic (1.18e-1)"	"unprognostic (2.03e-2)"	"unprognostic (6.50e-2)"	"unprognostic (2.25e-1)"	"unprognostic (4.20e-1)"	"prognostic favourable (4.28e-4)"	"unprognostic (8.62e-3)"	"unprognostic (1.55e-1)"	"unprognostic (4.41e-2)"	"unprognostic (7.71e-2)"	16.7	15.2	29.7	16.9	35.6	38.1	17.8	27.3	34.2	18.6	18.6	45.7	12.5	14.9	18.9	14.2	28.9	14.7	17.5	18.5	32.5	21.5	25.2	16.9	16.9	18.5	39.0	22.0	16.9	20.2	21.8	26.2	33.8	32.7	104.7	19.4	12.8	17.5	19.2	15.3	14.5	13.5	18.4	38.3	16.7	18.4	15.8	46.0	19.4	25.5	20.1	24.6	12.6	16.8	6.6	12.9	42.0	14.0	6.1	9.2	6.5	20.6	14.1	17.3	32.7	26.2	16.6	22.6	29.7	32.9	23.2	27.4	22.4	13.0	36.4	14.4	18.8	14.2	40.8	26.9	32.0	21.3	23.6	37.7	12.9	23.5	15.6	32.5	22.6	11.2	24.9	16.0	32.4	20.2	28.1	31.8	39.0	12.5	43.2	25.0	21.2	12.9	23.8	17.4	21.6	26.3	27.7	22.2	15.8	18.1	23.0	26.2	14.8	27.9	13.2	15.4	11.6	82.0	32.0	8.7	14.1	37.3	17.7	26.0	19.7	15.0	9.8	14.7	7.6	11.6	8.9	6.3	7.6	8.7	12.9	6.6	9.2	9.0	42.0	6.1	14.0	5.8	8.8	6.5	29.7	35.6	27.3	34.2	32.5	21.5	39.0	22.0	32.7	46.0
APEX1	"APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1"	ENSG00000100823	"Apurinic/apyrimidinic endodeoxyribonuclease 1"	P27695	14	20455191-20457772	"Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation"	"Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Lyase, Nuclease, Repressor, RNA-binding"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA000956, HPA002564, CAB004294, CAB047307"	Supported		Supported	Nucleoplasm			98000	Nucleoplasm		"CAB004294: AB_626685, CAB047307: , HPA000956: , HPA002564: AB_1078174"	"unprognostic (2.80e-3)"	"unprognostic (1.39e-1)"	"unprognostic (1.55e-2)"	"unprognostic (4.74e-3)"	"unprognostic (1.97e-2)"	"unprognostic (5.88e-2)"	"prognostic unfavourable (7.82e-5)"	"unprognostic (4.21e-2)"	"unprognostic (3.14e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.38e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.83e-2)"	"unprognostic (2.54e-1)"	"unprognostic (7.08e-2)"	43.9	52.8	30.6	33.2	32.5	55.6	43.6	24.1	44.9	38.5	41.9	37.3	28.4	44.1	53.2	30.1	40.7	42.9	46.4	34.4	28.0	27.4	44.4	61.3	31.8	44.5	30.2	31.1	64.7	48.4	31.8	21.7	29.4	34.4	36.1	39.8	36.0	35.5	38.9	53.2	41.2	37.6	40.9	30.1	51.0	41.7	20.9	28.3	73.2	51.2	38.5	48.4	41.8	32.7	35.0	53.0	1.5	23.7	20.6	32.5	38.4	43.9	54.1	48.5	44.7	34.1	49.3	41.8	41.3	44.5	61.6	53.5	39.4	43.7	84.9	36.9	31.5	47.2	57.7	43.7	57.2	37.9	24.6	34.4	32.0	65.6	35.9	109.2	35.8	50.9	48.3	40.1	39.8	51.4	39.9	28.0	49.3	42.8	69.9	46.0	47.8	48.9	77.8	54.5	35.6	51.7	59.3	58.5	37.3	44.8	55.9	44.4	34.0	49.4	33.1	32.5	54.5	32.7	38.5	37.6	65.1	57.3	14.5	69.4	41.0	0.1	23.7	1.5	19.0	20.5	25.9	35.0	23.8	22.6	46.8	31.4	32.5	28.3	1.5	20.6	12.4	53.0	14.1	38.4	30.6	32.5	24.1	44.9	28.0	27.4	30.2	31.1	34.4	28.3
APEX2	"APE2, APEXL2, XTH2, ZGRF2"	ENSG00000169188	"Apurinic/apyrimidinic endodeoxyribonuclease 2"	Q9UBZ4	X	55000357-55009057	"Enzymes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	"DNA-binding, Endonuclease, Exonuclease, Hydrolase, Lyase, Nuclease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA048577			Supported	"Nucleoplasm,Nucleoli fibrillar center,Vesicles"				"Nucleoplasm, Nucleoli fibrillar center"	Vesicles	"HPA048577: "	"unprognostic (2.90e-2)"	"prognostic favourable (6.17e-4)"	"unprognostic (4.32e-2)"	"unprognostic (2.39e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.62e-2)"	"prognostic unfavourable (6.13e-7)"	"unprognostic (5.89e-2)"	"unprognostic (4.87e-2)"	"prognostic favourable (5.21e-4)"	"unprognostic (7.46e-2)"	"unprognostic (3.16e-1)"	"unprognostic (6.86e-2)"	"unprognostic (1.03e-2)"	"unprognostic (3.17e-2)"	"unprognostic (1.40e-1)"	"prognostic favourable (6.63e-4)"	11.1	12.8	8.6	12.0	12.3	11.9	10.2	8.7	11.8	10.0	12.3	13.7	8.2	12.3	11.5	12.6	20.8	10.7	13.9	10.6	8.7	7.2	15.4	18.5	10.3	14.2	9.7	6.0	14.4	10.7	10.7	12.7	17.8	8.8	11.0	15.1	9.1	10.4	10.0	10.3	16.7	18.7	10.0	9.9	18.0	10.8	7.7	8.9	21.9	10.6	10.2	27.4	11.6	12.7	6.7	9.4	9.2	9.9	26.6	7.5	6.3	22.0	19.8	7.9	11.4	11.5	7.7	13.4	9.1	12.3	17.6	17.3	10.8	18.6	14.6	14.3	8.5	16.6	18.0	17.3	13.4	11.8	13.7	17.7	19.8	10.9	7.4	10.9	16.8	7.6	14.2	24.9	9.0	14.0	9.1	9.9	13.1	21.5	14.7	14.3	15.6	24.0	13.1	13.1	15.9	9.5	11.1	7.3	8.0	17.2	20.9	8.8	16.4	8.5	8.1	10.5	15.2	21.1	11.8	10.3	13.3	12.1	11.2	18.7	12.4	9.2	7.8	8.5	7.5	9.9	6.2	6.1	7.1	7.4	9.4	6.7	6.4	6.2	2.9	26.6	8.3	5.1	7.5	6.3	8.6	12.3	8.7	11.8	8.7	7.2	9.7	6.0	8.8	8.9
APIP	"APIP2, CGI-29, Mmrp19"	ENSG00000149089	"APAF1 interacting protein"	Q96GX9	11	34853094-34916499	"Enzymes, Predicted intracellular proteins"	"Amino-acid biosynthesis, Apoptosis, Methionine biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021188, HPA024131"	Approved		Approved	Nucleoplasm,Cytosol			77000	Nucleoplasm	Cytosol	"HPA021188: AB_10610977, HPA024131: AB_10602171"	"unprognostic (2.80e-1)"	"unprognostic (7.68e-2)"	"unprognostic (5.30e-2)"	"unprognostic (3.68e-3)"	"unprognostic (4.22e-2)"	"unprognostic (1.76e-1)"	"prognostic unfavourable (1.99e-4)"	"unprognostic (2.74e-2)"	"unprognostic (3.84e-2)"	"unprognostic (9.16e-2)"	"unprognostic (2.45e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.51e-1)"	"unprognostic (3.23e-1)"	"unprognostic (5.48e-2)"	"unprognostic (7.44e-2)"	"unprognostic (1.58e-2)"	23.2	29.8	12.0	13.7	18.7	9.6	15.8	7.6	12.6	12.7	13.8	17.9	16.8	10.5	15.3	10.8	12.2	13.9	12.1	15.4	14.5	11.7	24.8	21.8	16.2	14.4	21.5	11.7	13.2	19.7	13.4	10.3	12.5	21.1	14.1	12.6	10.4	18.5	20.4	48.7	6.8	13.9	16.0	27.8	13.9	19.1	9.7	21.1	23.9	19.0	12.9	11.5	19.0	16.1	14.2	25.6	14.9	19.8	17.5	15.8	10.6	8.5	9.1	10.9	2.5	8.9	8.8	4.9	12.6	12.2	12.4	14.2	5.4	7.5	26.2	7.7	4.6	10.2	19.8	8.5	16.1	16.1	18.8	13.5	9.7	13.7	13.7	37.4	10.4	8.6	6.3	7.9	13.0	10.2	31.7	16.1	8.6	8.2	17.9	17.3	8.6	21.7	11.5	31.8	8.9	12.8	12.3	9.2	4.4	15.8	12.7	15.5	13.3	11.6	8.5	9.4	9.4	24.0	3.0	15.8	11.9	29.5	11.7	8.0	11.9	4.7	16.9	14.9	11.0	17.5	13.6	14.2	13.4	11.9	25.6	13.4	13.8	11.7	4.1	17.5	19.8	16.5	15.8	10.6	12.0	18.7	7.6	12.6	14.5	11.7	21.5	11.7	21.1	21.1
APLF	"C2orf13, MGC47799, Xip1, ZCCHH1"	ENSG00000169621	"Aprataxin and PNKP like factor"	Q8IW19	2	68467561-68655862	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"basophil: 9.3"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 9.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA029396, HPA034642, HPA034643"	Uncertain		Supported	Nucleoplasm				Nucleoplasm		"HPA029396: AB_10610285, HPA034642: , HPA034643: AB_10602431"	"unprognostic (9.37e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.14e-1)"	"unprognostic (4.29e-3)"	"unprognostic (5.18e-3)"	"unprognostic (2.39e-3)"	"unprognostic (3.24e-1)"	"unprognostic (1.46e-1)"	"unprognostic (4.00e-2)"	"unprognostic (2.78e-1)"	"unprognostic (1.25e-3)"	"unprognostic (3.28e-1)"	"unprognostic (5.02e-3)"	"unprognostic (8.44e-2)"	"unprognostic (5.95e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.85e-3)"	5.2	4.4	3.8	7.3	6.5	2.8	8.2	1.1	5.0	8.0	5.7	3.1	3.8	2.6	8.8	4.0	10.6	3.3	4.1	3.8	4.7	2.0	3.7	5.1	3.4	5.8	3.6	2.1	4.3	3.8	4.1	5.1	6.2	3.2	8.5	2.7	2.3	6.4	4.8	5.4	9.2	3.3	9.2	5.6	5.7	3.6	4.1	6.1	5.1	4.4	7.5	5.8	6.9	6.9	1.1	1.4	9.3	1.2	1.5	2.2	0.9	3.6	0.9	4.1	4.1	5.5	7.4	2.1	3.2	5.8	1.9	2.4	2.3	3.0	6.7	2.6	2.6	1.2	0.5	4.4	4.5	6.2	0.8	5.5	0.8	1.4	2.6	1.9	4.9	4.1	3.7	2.7	4.1	1.4	1.1	4.8	1.9	0.6	2.6	5.0	2.2	1.6	3.6	1.4	3.0	3.8	2.0	1.2	2.7	3.2	0.4	3.8	0.3	1.1	3.6	6.7	1.5	3.4	2.5	4.4	2.4	5.1	2.9	2.7	4.3	9.3	0.9	3.1	0.9	1.2	1.0	1.1	1.4	1.3	1.3	1.0	1.5	0.8	0.0	1.5	0.9	1.4	2.2	0.9	3.8	6.5	1.1	5.0	4.7	2.0	3.6	2.1	3.2	6.1
ASL		ENSG00000126522	"Argininosuccinate lyase"	P04424	7	66075798-66093558	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 99.5"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB003696, HPA016646"	Enhanced		Approved	Cytosol			10000000	Cytosol		"CAB003696: AB_425316, HPA016646: AB_1845096"	"unprognostic (2.95e-2)"	"prognostic unfavourable (4.05e-6)"	"unprognostic (4.83e-1)"	"unprognostic (4.18e-3)"	"unprognostic (3.52e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.98e-1)"	"unprognostic (2.07e-1)"	"unprognostic (7.28e-2)"	"unprognostic (2.49e-2)"	"unprognostic (7.25e-2)"	"unprognostic (4.95e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.69e-1)"	"unprognostic (1.45e-1)"	"unprognostic (2.19e-1)"	"unprognostic (8.40e-3)"	5.6	4.8	4.0	8.0	4.3	7.3	5.9	7.2	7.4	5.5	17.2	3.7	7.8	20.8	5.0	7.1	7.7	4.9	19.5	4.3	3.7	4.3	16.0	99.5	8.1	4.5	4.4	6.2	5.9	10.4	3.3	5.8	3.3	7.2	5.4	12.4	5.8	7.1	5.7	2.4	4.1	16.6	3.4	3.2	8.6	12.6	2.1	3.5	1.2	7.1	7.9	5.9	5.2	5.9	8.6	19.3	20.7	18.4	30.4	9.2	10.7	18.2	7.5	4.1	14.8	9.4	7.3	9.0	12.8	11.2	18.3	16.7	16.8	22.6	5.6	20.5	16.8	5.0	2.6	21.7	5.3	4.6	3.4	7.4	7.3	26.1	17.7	8.4	21.7	13.7	7.9	12.8	20.5	18.0	13.1	10.7	10.1	13.0	1.7	11.6	6.2	9.7	4.5	4.3	19.2	13.3	11.0	7.1	9.7	11.7	40.8	4.4	17.8	7.6	20.4	23.2	12.0	9.2	16.5	11.7	6.1	7.3	21.9	16.0	18.7	12.1	18.1	20.7	7.7	18.4	6.5	8.6	5.2	6.1	19.3	5.6	3.7	4.0	4.0	30.4	13.8	1.2	9.2	10.7	4.0	4.3	7.2	7.4	3.7	4.3	4.4	6.2	7.2	3.5
AUH		ENSG00000148090	"AU RNA binding methylglutaconyl-CoA hydratase"	Q13825	9	91213815-91361913	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Branched-chain amino acid catabolism"	"Lyase, RNA-binding"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 41.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA004171	Enhanced				"Intracellular and membrane"					"HPA004171: AB_1845215"	"unprognostic (4.10e-2)"	"unprognostic (8.95e-2)"	"unprognostic (5.56e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.54e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.24e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.57e-1)"	"unprognostic (1.11e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.76e-1)"	"prognostic favourable (0.00e+0)"	"unprognostic (8.23e-3)"	"unprognostic (2.84e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.23e-1)"	13.0	39.6	14.3	15.6	20.1	3.8	15.2	22.5	20.7	14.1	19.8	10.5	25.3	19.2	11.1	16.0	8.9	10.7	11.4	30.4	15.4	19.7	50.4	21.3	9.7	6.7	19.1	9.0	11.8	20.7	27.0	10.1	13.1	16.3	23.8	14.4	10.6	20.1	35.4	31.0	6.7	16.0	10.4	15.2	7.7	17.7	6.1	12.1	9.1	17.5	11.8	8.9	10.2	10.5	8.7	5.8	16.1	4.6	9.9	10.0	5.3	4.5	4.4	6.3	3.2	7.8	8.4	9.7	4.1	5.2	3.2	3.7	2.5	5.9	5.4	4.3	4.3	6.7	9.3	5.2	4.6	41.3	7.9	3.6	4.9	14.8	5.9	5.3	3.8	7.0	6.6	2.6	8.9	3.9	5.1	8.1	3.7	4.4	7.2	11.9	7.8	6.5	4.3	5.0	9.2	14.0	2.4	6.4	4.6	6.1	14.7	7.7	2.7	3.5	4.0	3.2	4.0	4.7	3.9	9.3	7.8	1.8	5.1	4.3	2.1	15.2	4.6	16.1	6.9	3.2	7.9	7.8	7.6	10.0	4.2	8.7	9.6	8.8	7.1	9.9	2.1	5.8	9.3	5.3	14.3	20.1	22.5	20.7	15.4	19.7	19.1	9.0	16.3	12.1
CA1	Car1	ENSG00000133742	"Carbonic anhydrase 1"	P00915	8	85327608-85379014	"Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"		Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 156.0;intestine: 203.6"	"Cell line enriched"	"Detected in single"	1206	"HEL: 165.2"	"Group enriched"	"Detected in some"	10	"colorectal cancer: 3.4;stomach cancer: 0.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA006558, CAB025790"	Enhanced						7800000000			"CAB025790: , HPA006558: AB_1845989"	"unprognostic (1.44e-1)"	"unprognostic (7.56e-2)"	"unprognostic (1.70e-1)"	"unprognostic (3.57e-3)"	"unprognostic (2.08e-2)"	"unprognostic (1.66e-1)"	"unprognostic (2.84e-2)"	"unprognostic (2.03e-2)"		"unprognostic (1.73e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.04e-1)"	"unprognostic (5.61e-2)"	"unprognostic (3.01e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.95e-2)"	1.8	0.4	0.5	11.5	0.5	156.0	0.4	0.3	0.4	0.3	95.4	1.5	0.0	0.0	0.3	0.0	0.6	0.7	0.0	17.6	0.5	0.4	0.8	2.9	32.2	0.2	0.9	0.0	0.8	0.5	0.0	1.0	24.0	0.6	1.1	203.6	2.6	0.3	0.1	3.1	0.2	0.4	3.2	0.5	14.3	0.3	0.3	0.0	0.2	7.5	0.0	0.2	4.5	16.0	0.7	0.7	0.0	0.3	0.0	0.1	7.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	165.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.7	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.7	0.0	7.5	0.5	0.5	0.3	0.4	0.5	0.4	0.9	0.0	0.6	0.0
CA12	HsT18816	ENSG00000074410	"Carbonic anhydrase 12"	O43570	15	63321378-63382161	"Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins"		Lyase	"Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 103.5"	"Cell line enhanced"	"Detected in many"		"A549: 38.2;ASC TERT1: 40.3;RT4: 40.5;SK-BR-3: 32.5;T-47d: 52.3;U-138 MG: 55.8;U-87 MG: 67.0"	"Cancer enhanced"	"Detected in all"		"renal cancer: 109.3"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA008773, CAB025181, CAB062549, CAB068179, HPA073203"	Enhanced		Approved	Nucleoplasm,Vesicles			29000	Nucleoplasm	Vesicles	"CAB025181: , CAB062549: , CAB068179: , HPA008773: AB_1078394, HPA073203: "	"unprognostic (2.01e-1)"	"unprognostic (8.38e-3)"	"unprognostic (3.47e-1)"	"unprognostic (3.25e-3)"	"unprognostic (2.73e-2)"	"unprognostic (2.47e-2)"	"unprognostic (7.48e-2)"	"unprognostic (3.43e-3)"	"unprognostic (2.29e-1)"	"unprognostic (4.67e-2)"	"prognostic unfavourable (3.80e-6)"	"unprognostic (2.59e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.38e-1)"	"unprognostic (6.56e-2)"	"unprognostic (7.26e-2)"	"unprognostic (1.21e-1)"	3.7	0.3	4.7	15.0	27.4	0.3	14.5	3.7	2.3	15.7	32.0	2.6	5.0	0.4	9.8	12.3	42.8	8.5	2.6	1.6	4.9	1.4	103.5	0.3	1.2	0.3	1.8	0.2	2.1	43.8	0.3	3.9	5.9	16.9	3.8	30.3	8.5	8.2	17.9	0.5	44.1	2.4	18.1	0.1	0.4	2.2	1.3	6.7	0.0	1.7	18.4	25.9	10.6	14.5	0.3	0.2	0.6	0.7	0.3	0.2	0.0	0.0	38.2	0.6	0.0	5.1	40.3	2.0	2.7	2.5	0.4	0.7	0.2	0.0	0.0	9.4	2.2	0.2	0.0	1.8	1.1	0.0	1.3	0.0	2.6	0.0	0.1	0.0	0.0	15.2	2.1	11.6	3.7	0.4	0.0	0.0	0.5	22.0	0.0	0.0	0.6	6.0	0.0	0.0	0.0	0.0	40.5	0.3	0.0	0.1	32.5	0.0	52.3	0.0	0.0	55.8	3.0	1.8	0.0	0.0	0.0	0.0	67.0	0.0	0.1	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.3	0.1	0.2	0.6	0.3	0.7	0.2	0.1	0.0	4.7	27.4	3.7	1.3	4.9	1.4	1.8	0.2	16.9	6.7
CA13	"CAXIII, FLJ37995, MGC59868"	ENSG00000185015	"Carbonic anhydrase 13"	Q8N1Q1	8	85220587-85284073	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 56.7"	"Cell line enhanced"	"Detected in many"		"HEL: 16.1;RPTEC TERT1: 8.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA024689, CAB025567"	Enhanced		Uncertain	Nucleoplasm,Nucleoli,Vesicles			100000	Nucleoli	"Nucleoplasm, Vesicles"	"CAB025567: , HPA024689: AB_1846004"	"unprognostic (1.12e-2)"	"unprognostic (2.20e-1)"	"unprognostic (1.75e-1)"	"unprognostic (9.16e-5)"	"unprognostic (2.21e-2)"	"unprognostic (2.08e-1)"	"unprognostic (9.39e-2)"	"unprognostic (7.90e-3)"	"unprognostic (1.97e-1)"	"unprognostic (1.34e-2)"	"unprognostic (3.58e-2)"	"unprognostic (3.13e-1)"	"prognostic favourable (9.40e-4)"	"unprognostic (7.59e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.55e-2)"	"unprognostic (3.00e-1)"	2.6	2.6	2.0	1.9	3.1	0.5	2.9	2.4	2.4	3.2	18.2	0.8	0.0	14.2	1.8	1.7	6.7	1.4	25.6	5.8	1.6	1.9	10.4	17.1	9.5	2.4	2.0	0.1	2.2	1.6	9.3	6.5	1.0	5.7	2.6	3.7	1.9	7.0	1.0	1.9	7.1	56.7	1.9	5.2	2.2	7.0	0.9	0.9	0.4	10.3	3.9	5.6	2.9	5.2	0.8	2.1	3.2	2.5	0.5	0.5	1.0	0.3	0.4	0.9	0.1	0.6	0.7	0.4	1.1	1.1	0.1	3.1	7.5	5.8	0.4	0.5	1.3	2.4	2.3	3.0	0.2	1.6	1.0	16.1	2.1	6.9	1.6	0.2	0.7	2.4	0.5	0.2	1.3	1.7	4.1	3.2	2.7	0.1	0.3	0.2	0.5	0.5	0.2	2.4	0.2	8.7	0.3	0.3	0.1	0.5	0.0	1.6	0.6	0.8	1.6	3.0	4.3	0.1	1.6	1.3	0.6	2.0	6.3	2.3	2.8	3.2	2.5	1.3	0.4	0.7	0.2	0.2	0.2	0.1	2.1	0.8	0.3	0.5	0.9	0.5	0.8	0.9	0.1	1.0	2.0	3.1	2.4	2.4	1.6	1.9	2.0	0.1	5.7	0.9
CA14		ENSG00000118298	"Carbonic anhydrase 14"	Q9ULX7	1	150257159-150265078	"Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 20.9;retina: 29.4;seminal vesicle: 16.5;skeletal muscle: 24.1"	"Group enriched"	"Detected in some"	18	"AF22: 28.0;AN3-CA: 16.6;NTERA-2: 21.8;SK-MEL-30: 55.8"	"Group enriched"	"Detected in many"	7	"glioma: 4.9;melanoma: 23.2"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008482	Approved		Approved	"Plasma membrane"				"Plasma membrane"		"HPA008482: AB_1078395"	"unprognostic (3.06e-2)"	"unprognostic (1.67e-1)"	"unprognostic (2.10e-2)"	"unprognostic (3.25e-2)"	"prognostic favourable (8.47e-4)"	"unprognostic (7.28e-2)"	"unprognostic (4.48e-2)"	"unprognostic (1.49e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.47e-1)"	"unprognostic (5.46e-2)"	"unprognostic (1.73e-1)"	"unprognostic (5.89e-3)"	"unprognostic (1.91e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.22e-1)"	"unprognostic (5.80e-2)"	0.1	0.3	4.6	0.2	5.2	0.9	0.3	1.4	6.8	0.1	1.7	10.8	0.1	0.3	0.1	0.5	1.6	1.3	0.7	4.4	6.4	4.1	0.3	6.3	0.2	0.2	11.3	3.2	1.4	0.3	0.8	0.1	0.3	4.4	3.2	0.7	29.4	0.6	16.5	24.1	3.7	0.6	0.5	20.9	0.3	0.8	0.5	2.7	0.1	0.9	0.1	0.1	0.2	0.1	2.8	2.2	2.1	2.0	0.2	1.6	0.2	0.2	0.0	28.0	16.6	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.3	0.1	0.1	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	21.8	0.2	0.0	0.0	0.0	0.0	0.0	0.7	0.4	0.0	0.1	55.8	0.2	0.1	0.0	0.0	0.0	0.0	0.1	0.2	1.2	0.1	0.1	0.1	0.0	0.0	0.9	1.3	1.6	2.0	0.6	2.0	1.0	1.2	0.2	2.8	1.2	1.3	2.1	0.2	0.5	2.2	0.0	0.2	4.6	5.2	1.4	4.7	6.4	4.1	11.3	3.2	4.4	2.7
CA2	"CA-II, CAII, Car2"	ENSG00000104267	"Carbonic anhydrase 2"	P00918	8	85463852-85481493	"Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"		Lyase	"Disease mutation, FDA approved drug targets, Osteopetrosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 108.1;stomach 1: 171.5"	"Cell line enhanced"	"Detected in some"		"HaCaT: 33.1;HEK 293: 139.1;THP-1: 58.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"basophil: 20.3"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA001550, CAB010102"	Enhanced						790000000			"CAB010102: AB_626796, HPA001550: AB_1078393"	"unprognostic (6.78e-2)"	"unprognostic (3.06e-2)"	"unprognostic (1.05e-2)"	"unprognostic (1.63e-1)"	"unprognostic (2.59e-1)"	"unprognostic (9.24e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.72e-2)"	"unprognostic (1.07e-1)"	"unprognostic (5.23e-2)"	"unprognostic (1.57e-1)"	"unprognostic (9.89e-2)"	"prognostic favourable (5.57e-6)"	"unprognostic (2.45e-1)"	"unprognostic (2.03e-1)"	"unprognostic (1.32e-1)"	"unprognostic (6.49e-3)"	1.6	2.2	24.4	21.5	32.6	32.4	6.9	4.3	23.2	1.3	108.1	28.9	42.0	46.9	0.9	2.2	5.6	0.9	33.0	4.3	29.1	14.5	53.5	43.0	10.2	1.3	49.0	14.2	0.5	9.1	3.1	2.0	3.5	65.0	0.8	105.6	7.0	14.0	54.2	9.2	13.3	7.6	6.0	27.5	2.5	171.5	5.1	58.3	0.0	3.8	2.4	1.1	1.0	1.4	1.9	8.0	20.3	8.2	0.0	4.4	17.5	0.5	0.3	1.5	0.0	0.0	0.0	4.3	0.0	0.0	0.0	0.0	1.9	0.1	0.0	1.2	0.0	33.1	4.8	1.6	0.0	0.0	139.1	4.3	2.4	0.0	0.0	3.0	0.6	0.0	8.4	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	5.3	0.4	0.0	2.7	0.1	0.0	0.4	1.1	0.0	0.0	0.7	0.0	0.0	0.0	58.3	0.0	0.0	0.9	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	20.3	3.1	4.4	0.1	8.2	4.4	0.6	0.0	0.4	8.0	1.9	0.0	0.0	6.8	0.0	7.1	0.8	0.0	17.5	24.4	32.6	4.3	23.2	29.1	14.5	49.0	14.2	65.0	58.3
CA3	"CAIII, Car3"	ENSG00000164879	"Carbonic anhydrase 3"	P07451	8	85373436-85449040	"Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"		Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	12	"skeletal muscle: 347.5"	"Group enriched"	"Detected in some"	32	"HEL: 23.3;RH-30: 39.2"	"Group enriched"	"Detected in many"	7	"glioma: 23.1;prostate cancer: 9.4"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in single"		"plasmacytoid DC: 1.8"	"Low lineage specificity"	"Detected in single"			"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"CAB004967, HPA021775, HPA026700"	Enhanced						31000000			"CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991"	"prognostic favourable (4.24e-6)"	"unprognostic (1.40e-1)"	"unprognostic (1.50e-2)"	"unprognostic (2.22e-3)"	"unprognostic (4.71e-2)"	"unprognostic (8.43e-3)"	"unprognostic (3.56e-2)"	"unprognostic (4.04e-2)"	"unprognostic (1.11e-1)"	"unprognostic (3.68e-1)"	"unprognostic (4.71e-2)"	"unprognostic (3.54e-1)"	"unprognostic (3.19e-2)"	"unprognostic (1.18e-1)"	"unprognostic (9.96e-2)"	"unprognostic (1.39e-1)"	"unprognostic (2.19e-1)"	18.0	0.4	0.2	0.1	0.2	0.5	0.6	0.2	0.1	0.5	0.3	0.0	0.1	0.1	0.6	29.0	9.5	1.0	0.2	1.3	0.2	0.1	0.2	0.2	4.1	0.0	0.1	0.0	0.1	0.1	0.0	0.3	0.0	0.0	6.6	0.0	0.0	5.5	0.2	347.5	0.3	0.4	1.4	0.1	0.1	0.3	0.5	0.0	0.0	0.3	14.1	3.4	0.7	0.5	0.5	1.8	0.0	0.0	0.0	0.8	0.2	0.9	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.5	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.2	0.1	23.3	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	39.2	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.3	0.0	0.8	0.0	0.0	0.0	1.8	0.0	0.2	0.2	0.2	0.2	0.1	0.2	0.1	0.1	0.0	0.0	0.0
CA4	"CAIV, Car4, RP17"	ENSG00000167434	"Carbonic anhydrase 4"	P22748	17	60149936-60170899	"Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Lyase	"Disease mutation, FDA approved drug targets, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 81.7"	"Cell line enhanced"	"Detected in some"		"HEK 293: 1.4;HUVEC TERT2: 1.7;NTERA-2: 3.9;RPMI-8226: 1.5;RPTEC TERT1: 2.2"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in many"	4	"cerebellum: 50.1"	"Cell type enriched"	"Detected in some"	7	"neutrophil: 37.0"	"Lineage enriched"	"Detected in single"	370	"granulocytes: 37.0"	"Region enriched"	"Detected in all"	5	"cerebellum: 336.9"	"Low region specificity"	"Detected in many"			"HPA011089, HPA017258"	Enhanced		Supported	Vesicles			190000	Vesicles		"HPA011089: AB_1845996, HPA017258: AB_1845997"	"unprognostic (2.07e-2)"	"unprognostic (7.85e-2)"	"unprognostic (1.55e-2)"	"unprognostic (7.78e-3)"	"unprognostic (8.42e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.19e-2)"	"unprognostic (5.84e-2)"	"unprognostic (7.76e-2)"	"unprognostic (9.74e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.71e-2)"	"unprognostic (2.68e-3)"	"unprognostic (8.59e-2)"	"unprognostic (1.43e-1)"	"unprognostic (2.45e-1)"	"unprognostic (4.57e-2)"	32.2	0.9	3.4	9.8	4.4	5.7	46.4	50.1	11.8	2.3	81.7	2.0	31.5	1.4	2.3	17.4	0.9	1.7	12.2	8.8	4.7	2.6	12.0	0.3	33.3	2.4	3.5	5.2	1.9	9.5	3.3	5.1	3.2	3.0	2.4	54.9	20.3	4.8	24.0	10.0	1.0	3.2	1.1	2.1	4.9	2.5	1.2	0.3	0.2	23.1	5.0	0.2	1.7	7.9	0.0	0.0	37.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.7	0.1	0.3	0.0	0.0	0.0	0.5	0.9	0.0	0.3	0.0	0.0	0.4	1.4	0.0	0.0	0.8	0.0	0.0	0.0	0.3	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.3	3.9	0.0	0.0	0.2	1.5	2.2	0.0	0.8	0.4	0.2	0.0	0.0	0.0	0.6	0.0	0.2	0.9	0.5	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	5.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	37.0	0.0	0.0	0.0	0.0	0.0	3.4	4.4	50.1	11.8	4.7	2.6	3.5	5.2	3.0	0.3
CA5A	"CA5, CAV, CAVA"	ENSG00000174990	"Carbonic anhydrase 5A"	P35218	16	87881546-87936529	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"liver: 26.4"	"Cell line enhanced"	"Detected in some"		"Hep G2: 6.7"	"Cancer enriched"	"Detected in single"	26	"liver cancer: 2.0"					"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"														"unprognostic (1.91e-1)"	"unprognostic (8.64e-3)"	"unprognostic (3.36e-2)"	"unprognostic (6.11e-2)"	"unprognostic (2.49e-2)"	"unprognostic (2.96e-1)"	"unprognostic (8.39e-3)"	"unprognostic (3.50e-3)"	"unprognostic (1.42e-2)"	"unprognostic (1.12e-1)"	"unprognostic (6.55e-2)"	"unprognostic (4.23e-2)"	"unprognostic (7.99e-3)"	"unprognostic (1.77e-1)"	"unprognostic (5.03e-3)"	"unprognostic (3.37e-2)"	"unprognostic (2.76e-2)"	0.0	0.0	0.3	0.8	0.4	2.7	0.0	0.1	0.7	0.0	0.0			0.1	0.1	0.6	0.0	0.0	0.0	0.0	0.4	0.3	0.0	26.4	0.2	0.3	0.4		0.0	0.0	0.0	0.0	0.1		0.0	0.1		0.0	0.0	0.3	0.7	0.1	0.0	0.3	0.8	0.0	0.3			0.1		0.0	0.0	0.0	1.9	1.6	4.7	1.1	1.9	1.1	0.4	0.2	0.3	0.3	0.7	0.1	0.0	0.5	0.4	0.1	0.0	0.1	0.5	0.6	0.6	0.2	0.2	0.5	0.2	0.2	0.1	0.4	0.3	0.4	1.1	6.7	0.0	0.4	1.7	0.7	0.0	0.2	0.4	0.3	0.4	1.6	0.1	0.5	0.2	1.0	0.5	0.6	0.4	0.4	0.2	0.2	0.5	0.4	0.2	0.2	0.3	0.1	0.6	0.3	0.4	0.8	0.2	0.5	0.3	0.7	0.4	0.4	0.5	0.9	0.4	4.1	1.1	1.0	0.8	0.7	0.8	0.9	0.8	0.6	0.3	1.9	1.1	1.1	4.7	1.9	0.7	1.6	0.5	0.4										
CA5B		ENSG00000169239	"Carbonic anhydrase 5B"	Q9Y2D0	X	15688830-15788409	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 15.4;fHDF/TERT166: 17.5;hTERT-HME1: 23.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA012618	Uncertain		Supported	Mitochondria				Mitochondria		"HPA012618: AB_1846000"	"unprognostic (1.62e-2)"	"unprognostic (2.10e-3)"	"unprognostic (2.86e-1)"	"unprognostic (1.55e-3)"	"unprognostic (1.16e-2)"	"unprognostic (4.59e-5)"	"unprognostic (2.50e-1)"	"unprognostic (6.89e-4)"	"unprognostic (4.11e-1)"	"unprognostic (3.89e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.17e-1)"	"prognostic favourable (6.66e-6)"	"unprognostic (2.43e-1)"	"unprognostic (1.38e-1)"	"unprognostic (8.94e-2)"	"unprognostic (3.08e-1)"	9.3	4.6	10.6	4.9	11.1	4.1	10.2	3.1	7.8	28.7	3.6	11.5	1.4	2.2	9.8	3.7	8.1	9.5	9.1	6.5	9.9	8.2	10.3	7.8	7.3	8.8	12.2	6.7	15.2	4.4	16.8	4.4	3.9	13.1	6.2	4.7	29.5	8.3	6.2	2.0	7.5	4.1	9.4	7.1	5.3	5.4	23.0	8.1	2.3	8.9	10.9	11.6	6.3	9.4	4.3	3.5	2.7	3.6	7.9	13.3	7.0	2.7	1.6	1.9	3.1	5.8	15.4	1.1	2.9	3.7	2.1	3.1	0.8	1.8	0.8	3.0	17.5	3.0	6.8	3.3	3.8	0.7	3.2	1.5	2.1	0.7	5.7	1.9	3.3	3.6	3.5	2.8	23.0	3.1	0.7	2.0	10.1	1.5	1.5	1.5	0.7	12.2	0.9	1.4	1.4	3.3	2.0	1.7	3.6	4.0	1.4	2.6	2.0	1.9	4.2	2.5	1.7	13.6	1.6	1.5	1.5	0.8	2.8	3.8	4.7	2.7	3.0	0.3	13.1	3.6	11.4	3.6	13.3	12.3	3.5	4.3	9.8	8.3	1.7	7.9	2.3	0.5	10.0	7.0	10.6	11.1	3.1	7.8	9.9	8.2	12.2	6.7	13.1	8.1
CA6		ENSG00000131686	"Carbonic anhydrase 6"	P23280	1	8945867-8975092	"Enzymes, Predicted secreted proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	50	"salivary gland: 1237.9"	"Cell line enhanced"	"Detected in many"		"Daudi: 5.3;U-2197: 4.6"	"Low cancer specificity"	"Detected in some"			"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"naive CD8 T-cell: 15.4"	"Lineage enriched"	"Detected in many"	10	"T-cells: 15.4"					"Low region specificity"	"Detected in all"			"HPA028550, HPA028692"	Enhanced				"Secreted to digestive system"		34000000			"HPA028550: AB_10600105, HPA028692: AB_10601883"	"unprognostic (2.54e-5)"	"unprognostic (1.09e-1)"	"unprognostic (1.10e-1)"	"unprognostic (2.37e-1)"	"unprognostic (2.90e-1)"	"unprognostic (9.28e-2)"		"unprognostic (2.70e-3)"	"unprognostic (1.24e-1)"	"unprognostic (1.73e-1)"	"unprognostic (5.93e-2)"	"unprognostic (4.41e-2)"	"unprognostic (4.29e-5)"	"unprognostic (1.14e-1)"	"unprognostic (1.31e-1)"	"unprognostic (2.35e-1)"		0.3	0.0	0.1	0.0	0.1	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	1237.9	0.0	0.1	24.9	0.0	0.0	0.1	0.2	0.0	0.1	0.0	0.0	0.0	0.8	0.2	0.0	0.1	0.6	0.4	1.5	0.3	0.4	15.4	1.6	1.1	0.5	0.9	1.8	0.3	0.3	1.4	0.9	0.1	0.2	0.6	1.0	1.5	5.3	0.6	0.5	1.5	0.4	0.1	0.8	0.6	0.6	0.8	1.9	1.0	0.4	2.0	1.9	0.0	1.0	0.9	0.1	0.6	0.7	3.3	0.1	0.8	1.0	1.5	1.1	0.7	1.4	0.6	0.3	0.2	1.0	1.0	0.9	0.2	0.9	0.3	1.4	0.8	0.3	2.7	1.4	4.6	1.2	1.4	0.5	1.7	0.6	1.8	1.3	1.1	0.3	0.2	0.4	0.2	0.4	0.3	0.8	2.8	0.0	0.6	5.6	15.4	1.5	0.4	0.2	0.4	0.3	1.6	0.1	0.1	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0
CA7		ENSG00000168748	"Carbonic anhydrase 7"	P43166	16	66844379-66854153	"Enzymes, FDA approved drug targets, Predicted intracellular proteins"		Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"		"Tissue enriched"	"Detected in some"	5	"intestine: 37.2"	"Cell line enhanced"	"Detected in some"		"CACO-2: 1.2;HAP1: 1.8;NTERA-2: 1.5;REH: 3.3;SCLC-21H: 2.7;THP-1: 5.5"	"Cancer enhanced"	"Detected in some"		"colorectal cancer: 0.9"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA047237	Uncertain									"HPA047237: "	"unprognostic (8.77e-4)"	"unprognostic (5.23e-4)"	"unprognostic (1.57e-1)"	"unprognostic (1.96e-2)"	"unprognostic (2.19e-1)"	"unprognostic (2.16e-2)"		"unprognostic (7.90e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.84e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.69e-2)"	"unprognostic (7.12e-3)"	"unprognostic (8.47e-2)"	"unprognostic (5.20e-1)"	"unprognostic (1.90e-2)"	"unprognostic (6.46e-2)"	0.2	0.2	3.2	0.4	7.5	0.2	0.2	3.9	7.7	0.2	37.2	0.3	0.0	4.8	0.3	0.9	0.3	0.2	0.2	0.2	6.3	0.5	0.2	0.2	0.2	0.2	0.7	2.9	0.2	0.2	0.2	0.0	0.2	1.8	0.2	32.0	0.0	1.1	0.4	0.2	0.2	22.8	1.0	0.1	0.2	0.2	0.5	1.3	0.1	0.2	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.2	0.0	0.4	0.0	0.0	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.9	3.3	0.0	0.0	0.0	0.0	2.7	0.0	0.0	0.0	0.0	0.0	5.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.2	7.5	3.9	7.7	6.3	0.5	0.7	2.9	1.8	1.3
CA9	"CAIX, MN"	ENSG00000107159	"Carbonic anhydrase 9"	Q16790	9	35673856-35681159	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	8	"gallbladder: 70.4;pancreas: 47.4;stomach 1: 70.8"	"Cell line enhanced"	"Detected in some"		"A-431: 39.6;HDLM-2: 20.7;U-87 MG: 83.1"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in single"	10	"cerebellum: 7.3"	"Cell type enhanced"	"Detected in single"		"plasmacytoid DC: 1.1"	"Low lineage specificity"	"Detected in single"			"Region enriched"	"Detected in some"	4	"cerebellum: 13.8"	"Low region specificity"	"Detected in all"			"CAB005100, CAB017107, HPA055207"	Enhanced		Enhanced	"Plasma membrane,Cytosol"	"Intracellular and membrane"			"Plasma membrane"	Cytosol	"CAB005100: AB_2066539, CAB017107: , HPA055207: "	"unprognostic (8.01e-3)"	"unprognostic (1.34e-2)"	"unprognostic (2.28e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.15e-1)"	"prognostic unfavourable (1.71e-5)"	"unprognostic (1.47e-2)"	"unprognostic (3.90e-2)"	"unprognostic (1.29e-1)"	"unprognostic (6.24e-3)"	"unprognostic (1.13e-1)"	"prognostic unfavourable (2.22e-7)"	"unprognostic (7.29e-2)"	"prognostic favourable (9.50e-4)"	"unprognostic (2.97e-3)"	"unprognostic (8.67e-2)"	1.0	0.1	0.0	0.1	0.3	0.0	0.0	7.3	0.7	0.5	7.2	0.1	0.2	6.7	0.1	1.5	0.3	0.1	70.4	0.7	0.0	0.0	0.1	0.7	0.1	0.0	0.0	0.0	0.7	47.4	0.0	0.2	0.7	0.4	0.2	0.0	0.1	0.0	0.0	0.0	2.6	8.0	0.0	0.4	0.0	70.8	1.4	0.0	0.0	0.0	0.0	0.0	1.3	0.2	0.0	1.1	0.0	0.0	0.4	0.1	0.0	39.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.5	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.2	0.3	20.7	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	2.1	0.0	0.1	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	4.2	0.0	0.0	1.0	0.0	0.0	0.0	83.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	1.1	0.0	0.0	0.0	0.3	7.3	0.7	0.0	0.0	0.0	0.0	0.4	0.0
CBS	HIP4	ENSG00000160200	Cystathionine-beta-synthase	P35520	21	43053191-43076943	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Cysteine biosynthesis"	"Allosteric enzyme, Lyase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"		"Tissue enhanced"	"Detected in many"		"liver: 55.7;pancreas: 43.0"	"Cell line enhanced"	"Detected in many"		"BEWO: 40.2;HAP1: 38.3;HHSteC: 51.8;MCF7: 44.3;RPMI-8226: 42.4"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in single"	84	"neutrophil: 8.3"	"Lineage enriched"	"Detected in single"	84	"granulocytes: 8.3"									HPA001223	Supported		Approved	Nucleoli,Vesicles				Vesicles	Nucleoli	"HPA001223: AB_1846112"	"unprognostic (4.86e-2)"	"unprognostic (1.48e-2)"	"unprognostic (6.81e-2)"	"unprognostic (1.12e-3)"	"unprognostic (1.32e-1)"	"unprognostic (1.12e-1)"	"unprognostic (9.68e-4)"	"unprognostic (3.62e-1)"	"unprognostic (6.76e-3)"	"unprognostic (1.06e-1)"	"unprognostic (6.50e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.61e-2)"	"unprognostic (6.73e-3)"	"unprognostic (2.62e-1)"	"unprognostic (1.92e-2)"	"unprognostic (1.02e-1)"	1.3	1.5	6.5	2.4	5.1	0.4	1.0	12.3	6.7	4.8	1.3	2.0	0.8	1.6	0.9	0.8	0.8	2.0	2.1	2.0	5.6	5.5	1.3	55.7	1.7	1.4	4.8	2.8	13.9	43.0	0.3	1.4	1.4	2.3	4.0	0.7	2.8	9.3	3.4	0.8	0.6	2.9	1.4	3.7	0.8	2.7	2.2	3.3	0.8	5.0	0.8	0.9	2.6	0.8	0.0	0.0	8.3	0.0	0.0	0.0	0.0	6.3	3.8	5.0	19.6	11.3	7.3	40.2	7.8	2.0	3.2	3.3	11.8	0.3	0.0	4.2	14.7	0.4	38.3	2.7	0.6	0.0	4.8	2.6	15.3	14.2	51.8	1.6	3.8	4.4	0.4	3.5	3.1	8.6	29.6	22.3	2.4	44.3	2.7	0.0	4.7	6.7	0.0	0.0	42.4	0.1	3.5	10.4	15.3	17.2	1.0	7.4	6.1	20.0	1.1	0.2	9.9	0.1	0.8	7.8	6.2	8.8	3.6	2.3	11.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.3	0.0	0.0	0.0	0.0	0.0	6.5	5.1	12.3	5.2	5.6	5.5	4.8	2.8	2.3	3.3
CBSL		ENSG00000274276	"Cystathionine-beta-synthase like"	P0DN79	21	6444869-6468040	"Enzymes, Predicted intracellular proteins"	"Amino-acid biosynthesis, Cysteine biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 11.5;liver: 21.2;pancreas: 18.5"	"Cell line enhanced"	"Detected in many"		"AN3-CA: 35.7;NTERA-2: 66.2;SH-SY5Y: 21.1;U-266/70: 20.9"	"Low cancer specificity"	"Detected in some"							"Cell type enriched"	"Detected in single"	47	"neutrophil: 4.6"	"Lineage enriched"	"Detected in single"	47	"granulocytes: 4.6"									HPA001223	Supported		Approved	Nucleoli,Vesicles			190000	Vesicles	Nucleoli	"HPA001223: AB_1846112"	"unprognostic (2.39e-1)"	"unprognostic (1.54e-2)"	"unprognostic (1.15e-1)"	"unprognostic (4.78e-3)"	"unprognostic (6.49e-2)"	"unprognostic (1.42e-2)"	"unprognostic (1.28e-2)"	"unprognostic (6.62e-3)"	"unprognostic (1.17e-1)"	"unprognostic (3.62e-2)"	"unprognostic (7.50e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.04e-1)"	"unprognostic (3.17e-3)"	"unprognostic (8.44e-2)"	"unprognostic (2.46e-1)"	"unprognostic (3.61e-1)"	0.0	0.0		0.0		0.0	0.0		11.5	1.8	0.0			0.4	0.0	0.0	0.0	0.3	0.0	1.0			0.0	21.2	0.0	0.0			1.6	18.5	0.0		0.0		1.8	0.0		0.0	3.5	0.0	0.0	0.8	0.0		0.0	0.0	0.0			5.0		0.0	0.3		0.0	0.0	4.6	0.0	0.0	0.0	0.0	0.0	0.0	11.9	35.7	0.0	0.0	0.4	7.4	4.3	2.7	8.3	0.1	4.8	0.0	0.0	0.0	3.1	0.0	3.8	1.7	0.0	9.4	0.0	0.0	0.0	0.2	0.0	5.1	4.2	13.9	0.0	7.0	0.0	0.2	16.5	0.1	0.0	5.6	0.6	66.2	0.0	0.0	0.0	0.0	10.8	0.0	13.8	21.1	0.0	1.1	14.4	0.0	0.0	0.0	0.7	0.0	4.6	1.4	20.9	7.7	0.0	3.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.6	0.0	0.0	0.0	0.0	0.0										
CHAC1	MGC4504	ENSG00000128965	"ChaC glutathione specific gamma-glutamylcyclotransferase 1"	Q9BUX1	15	40952962-40956519	"Enzymes, Predicted intracellular proteins"	"Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"pancreas: 53.0;salivary gland: 39.9;skeletal muscle: 52.4"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 34.7;HHSteC: 26.5;hTCEpi: 42.0;SK-MEL-30: 29.6;U-266/70: 26.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"memory B-cell: 1.8"	"Group enriched"	"Detected in many"	6	"B-cells: 1.8;monocytes: 1.1;T-cells: 1.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA042708, HPA043505"	Approved		Approved	Mitochondria				Mitochondria		"HPA042708: , HPA043505: "	"unprognostic (6.04e-3)"	"unprognostic (2.81e-2)"	"unprognostic (7.47e-2)"	"unprognostic (2.84e-3)"	"unprognostic (6.57e-3)"	"unprognostic (2.00e-2)"	"unprognostic (5.59e-2)"	"unprognostic (2.43e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.72e-1)"	"unprognostic (3.11e-1)"	"unprognostic (1.51e-1)"	"prognostic unfavourable (2.23e-7)"	"unprognostic (1.37e-2)"	"unprognostic (1.44e-1)"	"unprognostic (1.67e-2)"	"unprognostic (3.91e-2)"	6.0	1.0	2.6	1.5	2.1	1.7	1.0	1.7	5.6	1.1	1.9	0.3	1.1	1.9	1.1	1.8	18.6	1.5	5.7	2.2	2.6	4.8	3.1	14.1	1.5	1.1	2.6	2.2	11.3	53.0	0.9	1.3	1.1	6.2	1.5	1.1	0.2	39.9	1.3	52.4	1.3	1.5	1.1	5.3	1.1	11.2	0.9	1.0	0.0	1.7	4.7	4.6	2.7	2.7	1.8	0.1	0.2	1.1	0.0	1.3	0.2	2.8	1.9	0.5	8.7	1.4	1.0	3.5	16.8	34.7	1.8	5.0	4.6	0.7	0.8	1.3	1.5	1.8	3.8	1.3	1.3	3.2	0.7	0.7	0.5	0.0	26.5	2.2	0.0	11.8	42.0	5.5	7.6	1.7	2.3	4.0	1.5	1.6	1.6	0.0	1.6	6.5	1.4	0.0	3.8	0.9	1.0	1.7	2.5	0.5	3.0	29.6	1.1	15.9	0.5	0.3	5.2	0.4	3.0	26.0	5.5	3.3	1.6	3.1	3.9	0.0	0.4	0.0	1.3	0.4	0.0	1.8	0.2	0.8	0.1	0.0	0.0	1.0	0.2	0.0	1.1	0.0	0.0	0.2	2.6	2.1	1.7	5.6	2.6	4.8	2.6	2.2	6.2	1.0
CHAC2	GCG1	ENSG00000143942	"ChaC cation transport regulator homolog 2"	Q8WUX2	2	53767792-53775196	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049235	Approved		Approved	Cytosol				Cytosol		"HPA049235: "	"unprognostic (2.22e-1)"	"unprognostic (1.31e-1)"	"unprognostic (2.11e-2)"	"unprognostic (3.91e-3)"	"unprognostic (1.61e-2)"	"unprognostic (4.74e-3)"	"prognostic unfavourable (3.80e-7)"	"unprognostic (5.52e-2)"	"unprognostic (1.74e-2)"	"unprognostic (1.30e-2)"	"unprognostic (1.36e-2)"	"unprognostic (3.09e-2)"	"unprognostic (4.28e-6)"	"unprognostic (1.52e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.55e-1)"	7.2	8.6	6.5	7.1	6.2	9.3	3.6	4.3	4.4	2.6	6.8	2.1	7.7	11.4	2.4	4.4	8.4	1.8	5.3	10.3	6.2	6.1	8.3	9.8	3.4	9.6	5.0	4.2	1.8	4.8	1.5	6.7	1.7	6.9	2.8	6.1	2.8	4.1	4.6	9.8	2.0	9.0	3.5	4.8	10.2	7.0	16.4	3.7	9.5	3.7	4.2	9.8	5.7	5.1	6.6	2.5	1.8	0.9	1.4	6.7	3.0	18.8	6.3	6.7	5.9	3.4	1.7	1.4	8.7	1.7	6.2	7.4	4.4	4.9	16.0	12.7	3.7	6.8	15.2	10.3	10.9	33.8	13.3	12.7	8.5	7.1	5.2	15.0	5.8	2.1	3.1	11.5	8.8	12.1	13.0	9.5	8.1	6.1	17.7	12.6	8.7	11.3	13.6	14.3	16.3	8.6	5.1	8.4	2.3	10.1	7.5	4.0	4.6	5.9	5.3	3.6	13.1	14.0	14.0	9.4	12.1	13.7	5.0	18.9	5.0	1.8	0.5	1.1	5.2	0.9	5.5	6.6	5.7	5.8	1.1	5.4	6.7	6.1	1.4	1.4	0.7	2.5	5.1	3.0	6.5	6.2	4.3	4.4	6.2	6.1	5.0	4.2	6.9	3.7
CLYBL	CLB	ENSG00000125246	"Citrate lyase beta like"	Q8N0X4	13	99606669-99897134	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Hydrolase, Lyase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 57.7"	"Cell line enhanced"	"Detected in many"		"SCLC-21H: 31.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039959, HPA040691"	Enhanced		Approved	Cytosol				Cytosol		"HPA039959: AB_10793857, HPA040691: AB_10794746"	"unprognostic (1.25e-2)"	"unprognostic (1.94e-1)"	"unprognostic (2.30e-3)"	"unprognostic (7.57e-3)"	"unprognostic (3.69e-1)"	"unprognostic (2.90e-2)"	"unprognostic (1.57e-3)"	"unprognostic (2.91e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.34e-1)"	"unprognostic (2.49e-2)"	"unprognostic (2.85e-1)"	"prognostic favourable (6.66e-16)"	"unprognostic (3.74e-2)"	"unprognostic (5.41e-2)"	"unprognostic (4.78e-2)"	"unprognostic (7.82e-2)"	4.2	11.6	6.2	10.4	9.4	2.6	6.0	6.7	6.4	4.6	11.2	3.8	4.8	13.6	5.2	7.6	6.4	4.7	8.3	12.3	5.1	6.3	35.0	57.7	4.7	9.6	7.9	8.6	3.5	15.0	6.1	5.7	2.2	12.5	4.2	12.3	8.9	8.7	5.5	22.2	5.7	12.5	8.6	4.5	5.5	4.8	10.7	4.3	4.6	7.0	13.3	8.2	4.9	4.4	11.0	7.5	1.2	6.7	9.2	16.7	5.5	0.2	1.3	9.8	4.4	4.6	4.3	2.1	0.4	0.9	0.8	1.5	0.2	7.2	1.7	2.8	0.5	2.2	0.8	1.6	1.1	8.6	1.4	10.9	2.6	6.7	3.2	5.8	0.8	2.3	4.9	0.1	3.8	1.2	1.5	5.7	0.9	2.4	2.6	8.1	6.3	2.0	3.4	0.4	4.0	9.7	0.6	31.7	4.8	1.9	2.2	1.9	4.7	7.6	0.1	0.4	1.1	0.8	1.5	13.3	2.6	0.3	6.8	8.6	1.3	1.2	3.3	0.3	7.5	6.7	9.0	10.9	13.3	10.6	6.7	11.0	10.3	12.1	0.5	9.2	3.2	7.5	16.7	5.5	6.2	9.4	6.7	6.4	5.1	6.3	7.9	8.6	12.5	4.3
CSAD	"CSD, PCAP"	ENSG00000139631	"Cysteine sulfinic acid decarboxylase"	Q9Y600	12	53157663-53180909	"Enzymes, Plasma proteins, Predicted intracellular proteins"		"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 38.7;T-47d: 23.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	5	"neutrophil: 16.3"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 16.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA039487	Approved				"Intracellular and membrane"					"HPA039487: AB_10672776"	"unprognostic (1.00e-1)"	"unprognostic (3.28e-2)"	"prognostic unfavourable (9.50e-4)"	"unprognostic (1.57e-1)"	"unprognostic (7.99e-2)"	"prognostic favourable (6.33e-4)"	"prognostic favourable (1.37e-4)"	"unprognostic (2.46e-2)"	"unprognostic (7.87e-3)"	"unprognostic (1.01e-1)"	"prognostic favourable (3.39e-4)"	"unprognostic (3.48e-2)"	"prognostic unfavourable (1.93e-6)"	"unprognostic (4.59e-2)"	"unprognostic (3.47e-1)"	"unprognostic (1.38e-1)"	"prognostic favourable (6.81e-6)"	30.3	11.4	23.4	12.4	17.8	24.8	26.0	26.4	20.8	17.8	13.1	23.5	24.7	12.4	27.7	39.4	12.3	16.5	14.6	9.9	19.3	10.2	14.9	39.5	12.7	12.5	18.3	22.4	24.6	15.3	16.4	18.4	9.5	17.6	24.8	12.1	19.5	23.2	19.6	12.9	41.9	12.0	14.8	18.9	16.5	12.4	18.5	18.9	12.1	16.0	9.9	10.2	10.5	16.2	2.1	2.2	16.3	2.0	1.5	3.0	0.4	1.6	2.9	7.1	3.0	38.7	16.0	2.6	6.3	1.4	2.7	2.2	1.8	3.9	2.1	4.8	3.4	5.6	3.1	4.9	1.6	2.8	3.8	3.4	7.2	3.7	3.5	1.3	2.2	19.6	6.2	4.0	5.1	2.4	3.5	19.1	2.5	13.4	0.7	4.0	1.4	2.8	2.8	0.4	4.9	3.5	4.2	3.6	2.8	6.2	9.0	2.3	23.5	2.8	5.5	7.9	1.6	2.3	1.8	5.5	1.3	1.1	6.6	3.6	3.1	3.5	2.0	2.2	1.3	1.1	0.8	1.2	1.9	0.8	0.9	2.1	2.5	1.4	16.3	1.5	1.2	2.2	3.0	0.4	23.4	17.8	26.4	20.8	19.3	10.2	18.3	22.4	17.6	18.9
CTH		ENSG00000116761	"Cystathionine gamma-lyase"	P32929	1	70411218-70439851	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Amino-acid biosynthesis, Cysteine biosynthesis"	"Calmodulin-binding, Lyase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	6	"liver: 104.5"	"Cell line enhanced"	"Detected in many"		"HHSteC: 19.7;Karpas-707: 30.6;SK-MEL-30: 40.0"	"Group enriched"	"Detected in all"	5	"liver cancer: 30.0;testis cancer: 8.1"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"B-cells: 4.5;T-cells: 6.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021591, HPA023300"	Enhanced						25000			"HPA021591: AB_1847321, HPA023300: AB_1847322"	"unprognostic (3.41e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.76e-1)"	"unprognostic (7.66e-2)"	"unprognostic (2.45e-3)"	"prognostic favourable (8.69e-4)"	"unprognostic (1.71e-1)"	"unprognostic (1.95e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.05e-3)"	"unprognostic (3.25e-2)"	"unprognostic (1.03e-1)"	"unprognostic (8.97e-2)"	"unprognostic (3.05e-3)"	"unprognostic (1.26e-1)"	2.2	8.3	2.3	1.0	3.2	2.2	2.0	3.7	3.6	1.9	3.3	2.2	1.8	3.3	1.7	1.4	2.7	2.3	1.5	1.6	2.1	2.7	8.2	104.5	2.2	1.0	2.4	2.2	18.3	11.6	1.5	1.7	1.0	3.2	2.9	4.1	11.2	4.8	2.8	2.1	1.0	3.2	1.2	2.4	0.8	3.7	5.4	1.3	0.0	11.4	1.2	1.5	2.7	1.2	4.5	1.3	1.1	0.6	0.6	6.4	1.1	5.0	0.7	3.4	4.8	4.2	2.4	7.6	2.0	1.8	1.7	7.6	1.4	3.1	2.7	1.6	1.4	2.4	13.3	1.4	3.5	8.4	2.9	3.2	2.5	4.3	19.7	3.7	0.8	3.7	11.9	3.6	4.2	1.5	6.4	30.6	1.1	1.4	1.3	0.8	3.5	2.7	1.3	1.8	7.7	3.5	0.0	1.9	1.6	3.2	3.8	40.0	1.3	2.0	0.5	0.5	3.9	2.7	1.9	11.8	6.9	1.4	4.7	7.5	1.3	1.1	0.6	0.2	2.5	0.4	4.6	4.5	2.3	3.5	1.0	2.9	6.4	3.1	0.9	0.6	0.5	1.3	0.7	1.1	2.3	3.2	3.7	3.6	2.1	2.7	2.4	2.2	3.2	1.3
DDC	AADC	ENSG00000132437	"Dopa decarboxylase"	P20711	7	50458436-50565457	"Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins"	"Catecholamine biosynthesis"	"Decarboxylase, Lyase"	"Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	7	"intestine: 90.1;kidney: 68.1"	"Group enriched"	"Detected in some"	8	"CACO-2: 17.4;Hep G2: 15.3;SCLC-21H: 44.0;SH-SY5Y: 45.7"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"midbrain: 7.9;pons and medulla: 3.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	10	"midbrain: 90.4;pons and medulla: 40.7"	HPA017742	Enhanced		Approved	"Actin filaments"			380000	"Actin filaments"		"HPA017742: AB_1847832"	"unprognostic (1.04e-1)"	"unprognostic (3.68e-2)"	"unprognostic (2.57e-2)"	"unprognostic (3.49e-5)"	"unprognostic (1.17e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.28e-1)"	"unprognostic (5.15e-2)"	"unprognostic (4.69e-2)"	"unprognostic (5.44e-2)"	"unprognostic (9.36e-3)"	"unprognostic (5.24e-2)"	"unprognostic (1.76e-3)"	"unprognostic (1.60e-1)"	"unprognostic (3.55e-1)"	"unprognostic (7.65e-2)"	"unprognostic (1.16e-1)"	0.3	10.9	0.3	3.0	0.7	0.0	0.3	0.3	0.4	0.3	36.7	0.4	0.3	33.5	0.3	1.8	0.3	0.0	0.7	0.3	0.3	1.3	68.1	11.7	0.7	0.3	7.9	0.3	0.4	9.8	0.0	0.3	0.3	3.4	0.4	8.1	0.4	0.3	0.3	0.3	0.1	90.1	0.3	0.3	0.3	4.3	0.6	0.5	0.3	0.3	0.4	0.3	0.4	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	17.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.3	0.0	0.0	3.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.4	0.0	44.0	45.7	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.7	0.3	0.4	0.3	1.3	7.9	0.3	3.4	0.5
DDT	DDCT	ENSG00000099977	"D-dopachrome tautomerase"	P30046	22	23971365-23980469	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Melanin biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"blood: 52.8;liver: 58.4"	"Cell line enhanced"	"Detected in all"		"HEK 293: 67.6"	"Low cancer specificity"	"Detected in all"							"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											HPA049871	Approved		Approved	Mitochondria				Mitochondria		"HPA049871: "	"unprognostic (1.77e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.22e-2)"	"unprognostic (8.09e-2)"	"unprognostic (4.00e-3)"	"unprognostic (2.02e-3)"	"unprognostic (6.58e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"	"unprognostic (6.06e-3)"	"unprognostic (1.12e-1)"	"unprognostic (7.34e-2)"	"unprognostic (3.30e-1)"	"unprognostic (3.81e-1)"	"unprognostic (2.61e-3)"	9.7	6.6	5.4	3.4	4.8	8.8	4.5	2.1	4.4	3.0	9.8			11.8	2.7	4.3	5.8	2.8	1.4	7.7	4.2	4.0	11.3	58.4	3.2	2.9	5.4		4.1	14.4	1.3	1.8	2.5		5.8	6.4		7.1	4.4	10.4	3.7	11.6	2.0	4.6	3.2	8.2	1.2			3.7		2.7	4.3	3.2	30.4	52.8	27.8	38.0	23.8	29.0	28.6	26.7	11.4	4.0	9.3	7.6	6.7	24.2	7.8	5.3	6.8	7.1	10.1	7.7	25.6	7.3	4.1	22.2	9.8	9.7	4.5	10.8	67.6	15.4	15.6	21.9	7.7	33.8	15.5	6.7	7.4	6.8	6.0	7.3	13.9	10.4	6.8	13.1	7.4	30.6	12.0	34.5	16.3	7.4	36.6	12.1	9.9	13.5	13.0	16.1	30.4	22.9	7.7	10.6	8.4	7.1	15.8	7.2	8.1	32.0	10.6	16.1	13.9	12.6	13.6	20.7	38.0	27.8	19.9	32.4	20.3	30.4	24.1	21.1	35.7	28.4	21.9	21.3	24.2	23.8	29.6	52.8	29.0	28.6										
DERA	"CGI-26, DEOC"	ENSG00000023697	"Deoxyribose-phosphate aldolase"	Q9Y315	12	15911172-16037282	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA055897			Supported	Nucleoplasm			180000	Nucleoplasm		"HPA055897: "	"unprognostic (3.05e-1)"	"unprognostic (1.26e-1)"	"unprognostic (1.06e-2)"	"unprognostic (7.26e-2)"	"unprognostic (8.12e-2)"	"unprognostic (7.74e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.47e-2)"	"unprognostic (2.76e-1)"	"unprognostic (1.87e-1)"	"prognostic unfavourable (1.32e-4)"	"unprognostic (2.13e-1)"	"unprognostic (1.09e-1)"	"unprognostic (8.74e-2)"	"unprognostic (2.17e-2)"	"prognostic favourable (3.64e-5)"	"unprognostic (3.66e-2)"	20.3	12.0	10.5	10.8	10.8	7.5	11.5	5.2	7.7	11.3	30.3	11.4	12.7	20.2	21.5	14.7	20.0	8.2	11.1	11.7	10.1	9.1	40.9	51.5	13.6	14.1	12.5	6.5	5.8	16.9	6.6	27.5	12.3	11.3	9.2	21.2	11.0	11.4	11.3	15.3	12.4	46.7	10.4	14.6	14.6	10.5	5.5	11.0	13.8	26.6	16.7	14.3	10.1	13.1	12.4	30.2	14.1	28.2	17.1	14.9	15.7	19.9	16.5	13.0	11.4	8.8	20.2	26.6	11.7	11.0	15.9	20.5	19.9	37.1	13.6	10.4	14.9	14.2	14.1	15.0	28.3	22.8	8.2	12.0	8.3	18.7	12.7	12.7	8.2	13.4	17.4	13.0	26.7	22.9	1.7	4.2	29.0	7.3	9.4	10.6	28.4	8.2	14.4	28.6	8.5	39.9	7.2	9.5	16.0	22.0	7.3	22.9	39.7	15.9	22.6	17.0	11.2	7.7	12.4	4.5	6.6	23.5	21.8	12.8	12.5	5.4	24.4	14.1	7.2	27.1	7.9	12.4	7.8	7.7	30.2	11.4	8.6	6.9	6.5	17.1	28.2	16.5	14.9	15.7	10.5	10.8	5.2	7.7	10.1	9.1	12.5	6.5	11.3	11.0
DGLUCY	"C14orf159, FLJ39975"	ENSG00000133943	"D-glutamate cyclase"	Q7Z3D6	14	91060333-91225632	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 82.9"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"neutrophil: 57.9"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA041423, HPA052932"	Approved		Supported	Cytosol				Cytosol		"HPA041423: AB_10795540, HPA052932: "	"unprognostic (5.02e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.56e-1)"	"prognostic favourable (4.28e-4)"	"unprognostic (1.28e-1)"	"unprognostic (2.26e-1)"	"unprognostic (3.58e-2)"	"prognostic favourable (9.48e-5)"	"unprognostic (3.56e-1)"	"prognostic favourable (7.28e-4)"	"unprognostic (2.30e-1)"	"unprognostic (1.74e-1)"	"prognostic favourable (3.77e-15)"	"unprognostic (1.50e-1)"	"unprognostic (9.51e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.57e-3)"	12.5	18.7	23.4	15.9	23.1	10.7	9.3	27.3	22.6	14.6	16.7	18.1	16.0	13.8	16.8	13.1	16.0	21.9	12.5	63.9	18.8	16.6	20.1	13.1	13.7	11.2	20.1	19.2	13.4	9.3	29.3	14.2	9.2	19.0	13.3	17.0	11.3	17.4	22.3	82.9	13.9	12.3	20.0	18.5	17.3	18.9	12.2	21.6	11.2	16.8	29.1	14.1	19.4	11.4	9.4	19.8	57.9	19.3	5.6	12.0	7.0	2.7	7.4	3.8	9.1	15.5	14.7	9.9	2.8	8.0	8.9	9.2	4.8	21.4	18.5	21.5	8.5	8.2	10.4	11.3	3.7	10.2	4.3	12.4	3.7	6.1	22.8	12.6	18.1	22.6	4.9	4.9	1.9	15.8	6.2	25.3	8.4	0.7	9.9	12.0	7.6	0.7	17.1	7.4	13.4	15.1	11.7	10.5	5.3	4.8	8.3	3.4	14.7	10.7	11.3	2.7	2.3	8.0	2.6	14.5	10.3	6.2	13.9	16.6	1.7	13.7	13.6	8.1	8.8	19.3	9.0	9.4	5.9	7.2	19.8	7.0	4.9	6.0	57.9	5.6	15.5	6.2	12.0	7.0	23.4	23.1	27.3	22.6	18.8	16.6	20.1	19.2	19.0	21.6
ECHDC1	dJ351K20.2	ENSG00000093144	"Ethylmalonyl-CoA decarboxylase 1"	Q9NTX5	6	127288710-127343609	"Enzymes, Plasma proteins, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035445, HPA035446"	Uncertain		Approved	Vesicles				Vesicles		"HPA035445: AB_10669860, HPA035446: "	"unprognostic (9.57e-2)"	"unprognostic (1.63e-2)"	"unprognostic (2.46e-3)"	"unprognostic (1.34e-1)"	"unprognostic (4.09e-1)"	"unprognostic (3.68e-2)"	"unprognostic (5.03e-3)"	"unprognostic (4.89e-3)"	"unprognostic (4.97e-2)"	"unprognostic (1.76e-1)"	"unprognostic (3.99e-1)"	"unprognostic (9.97e-2)"	"unprognostic (8.21e-3)"	"unprognostic (6.83e-2)"	"unprognostic (2.86e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.40e-2)"	40.1	16.8	20.8	16.5	23.1	6.8	21.9	16.6	21.4	18.6	27.2	12.0	12.8	21.9	13.7	15.5	20.6	11.4	16.1	20.0	19.4	18.0	44.4	44.3	26.8	17.8	27.3	16.5	11.9	14.2	14.5	16.1	17.0	23.1	19.8	26.3	15.1	22.2	14.5	22.0	13.3	25.8	30.1	27.3	14.1	18.1	8.3	20.9	20.7	42.4	14.2	19.4	24.2	22.6	13.2	29.6	13.4	31.2	6.4	11.6	16.9	15.8	12.6	18.1	16.7	27.0	25.7	15.4	25.8	31.5	22.3	28.5	21.9	12.1	24.0	22.3	24.5	13.1	0.0	19.4	28.3	14.2	12.1	31.9	17.0	34.8	24.1	42.6	18.0	28.9	23.4	20.8	17.7	20.1	39.5	14.6	29.7	14.9	28.1	19.8	15.0	15.7	13.3	22.4	19.6	40.6	19.6	20.9	20.3	14.5	0.5	35.5	0.5	49.9	20.8	13.7	22.0	34.6	28.8	18.7	37.6	31.6	25.1	37.4	32.2	6.2	31.2	10.0	11.0	25.6	11.6	12.8	9.5	10.8	29.6	13.2	11.6	11.6	13.4	6.4	17.9	22.6	9.6	16.9	20.8	23.1	16.6	21.4	19.4	18.0	27.3	16.5	23.1	20.9
ECHS1	SCEH	ENSG00000127884	"Enoyl-CoA hydratase, short chain 1"	P30084	10	133362480-133373689	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Lyase	"Disease mutation, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 148.2"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003783, HPA021995, HPA022476"	Enhanced		Enhanced	Mitochondria			1500000	Mitochondria		"CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975"	"unprognostic (3.68e-1)"	"unprognostic (2.46e-3)"	"unprognostic (9.57e-2)"	"unprognostic (4.70e-2)"	"unprognostic (1.59e-1)"	"unprognostic (3.14e-1)"	"unprognostic (2.51e-3)"	"unprognostic (2.30e-1)"	"unprognostic (1.82e-2)"	"unprognostic (2.28e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.27e-1)"	"prognostic favourable (8.57e-5)"	"unprognostic (2.84e-2)"	"unprognostic (1.19e-2)"	"unprognostic (3.04e-2)"	"unprognostic (2.50e-2)"	36.5	18.7	16.6	9.1	16.6	5.0	15.2	8.2	18.3	8.8	21.8	13.0	34.7	22.8	9.5	14.1	16.5	12.2	17.4	29.8	14.6	11.5	62.1	148.2	6.3	7.8	14.8	10.3	11.6	16.3	9.2	11.0	12.8	11.1	13.9	14.0	11.0	40.2	38.4	35.7	8.8	32.1	9.9	11.9	7.3	11.0	10.2	10.2	3.9	16.2	17.5	13.0	11.2	7.8	39.4	53.7	18.3	45.7	33.5	32.1	44.5	28.7	36.1	19.7	49.1	28.6	18.4	18.0	21.2	28.0	29.6	25.1	79.2	28.0	21.7	18.4	23.8	27.0	25.5	21.5	21.4	16.6	44.8	21.6	21.8	56.3	24.0	28.0	15.4	20.5	18.6	19.6	25.1	26.2	19.5	19.1	28.8	68.2	13.9	54.7	13.7	43.4	24.0	23.9	11.6	36.5	36.9	12.7	20.2	21.9	36.4	27.5	28.3	27.0	21.0	13.4	19.4	27.7	27.9	14.4	8.8	24.6	31.7	15.3	11.0	17.0	41.7	18.3	24.9	45.7	32.1	39.4	28.1	27.1	53.7	32.2	28.9	27.9	4.4	33.5	34.3	23.2	26.0	44.5	16.6	16.6	8.2	18.3	14.6	11.5	14.8	10.3	11.1	10.2
EHHADH	ECHD	ENSG00000113790	"Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase"	Q08426	3	185190624-185281990	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"kidney: 37.1;liver: 91.2"	"Low cell line specificity"	"Detected in many"			"Group enriched"	"Detected in all"	7	"liver cancer: 42.2;renal cancer: 25.4"	"Low region specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036401, HPA042021"	Enhanced									"HPA036401: AB_10670165, HPA042021: "	"unprognostic (1.20e-1)"	"unprognostic (5.99e-2)"	"unprognostic (2.17e-3)"	"unprognostic (2.69e-2)"	"unprognostic (6.82e-2)"	"unprognostic (1.48e-1)"	"unprognostic (4.79e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.73e-1)"	"unprognostic (3.89e-2)"	"unprognostic (3.19e-3)"	"unprognostic (1.87e-1)"	"prognostic favourable (1.28e-5)"	"unprognostic (1.93e-1)"	"unprognostic (1.53e-1)"	"unprognostic (2.96e-2)"	"unprognostic (2.80e-1)"	4.1	1.2	1.2	1.7	1.4	0.1	1.5	0.5	1.2	1.7	6.4	0.8	0.4	5.2	1.0	2.0	2.9	0.8	3.0	3.2	1.2	0.9	37.1	91.2	1.9	1.0	1.7	0.7	0.8	2.5	2.7	0.9	1.3	2.1	1.7	2.6	8.3	2.7	0.4	0.7	1.1	9.9	1.0	1.4	1.7	2.4	0.9	0.9	1.4	2.1	1.7	1.2	1.8	1.0	1.5	6.0	0.2	2.2	2.7	2.7	1.1	8.2	3.5	1.0	0.0	5.2	4.5	1.1	4.0	1.2	2.6	2.9	15.1	5.2	0.0	15.7	3.9	4.0	0.0	3.3	5.5	11.0	3.7	5.8	0.9	15.2	3.4	0.7	0.1	6.3	4.3	2.6	2.4	3.8	3.8	4.3	5.0	4.3	0.1	3.4	2.1	4.4	0.0	7.0	0.3	10.8	4.7	3.1	4.5	7.8	4.5	7.2	16.6	6.8	1.8	1.7	2.6	1.3	0.3	1.2	3.7	0.3	0.5	2.6	2.8	0.2	2.2	0.0	1.6	2.1	1.0	1.5	1.1	2.4	6.0	0.2	1.6	2.7	0.1	2.7	2.0	2.4	1.4	1.1	1.2	1.4	0.5	1.2	1.2	0.9	1.7	0.7	2.1	0.9
ENO1	"ENO1L1, MBP-1, MPB1, PPH"	ENSG00000074800	"Enolase 1"	P06733	1	8861000-8879250	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	"Glycolysis, Plasminogen activation, Transcription, Transcription regulation"	"DNA-binding, Lyase, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			"CAB018614, HPA068284, HPA068721, CAB069394"	Supported		Enhanced	"Plasma membrane,Cytosol"			490000000	"Plasma membrane, Cytosol"		"CAB018614: AB_2099061, CAB069394: , HPA068284: , HPA068721: "	"unprognostic (6.51e-3)"	"unprognostic (9.50e-3)"	"unprognostic (3.56e-2)"	"unprognostic (1.86e-1)"	"prognostic unfavourable (2.71e-4)"	"unprognostic (1.82e-2)"	"prognostic unfavourable (1.30e-8)"	"unprognostic (2.37e-2)"	"unprognostic (5.58e-2)"	"unprognostic (9.72e-2)"	"unprognostic (1.67e-2)"	"unprognostic (1.46e-1)"	"unprognostic (7.53e-2)"	"unprognostic (6.20e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.22e-1)"	"unprognostic (1.36e-3)"	68.6	57.7	92.7	94.9	109.6	121.8	73.4	46.6	119.4	47.3	63.8	74.6	21.7	71.3	44.9	24.2	138.2	52.2	55.0	45.2	79.1	70.7	180.4	165.4	64.8	80.3	74.9	62.7	58.2	31.6	52.7	35.5	70.5	88.6	38.6	66.4	62.6	106.1	69.1	45.0	74.6	70.3	84.0	56.4	80.0	44.3	31.7	48.8	98.8	55.4	91.0	119.3	73.5	62.9	38.7	114.1	22.1	105.4	55.5	63.7	159.3	180.7	158.0	76.2	65.2	63.8	71.3	69.1	98.3	109.0	211.8	199.1	101.1	105.0	130.3	131.2	118.2	89.2	129.4	262.3	216.0	88.9	136.7	110.0	160.5	125.6	95.9	219.2	67.8	73.6	79.6	167.7	255.0	135.6	120.5	51.0	137.3	89.5	82.6	117.4	83.1	158.6	85.6	113.6	212.8	250.7	43.1	103.1	63.7	115.3	167.9	121.2	84.1	65.7	123.9	146.7	129.9	125.1	167.1	145.5	103.2	197.7	227.8	179.8	123.1	13.9	105.4	20.8	52.3	75.8	59.1	38.7	55.8	53.8	114.1	32.7	45.6	47.8	22.1	55.5	72.4	31.2	63.7	159.3	92.7	109.6	46.6	119.4	79.1	70.7	74.9	62.7	88.6	48.8
ENO2		ENSG00000111674	"Enolase 2"	P09104	12	6913745-6923698	"Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	Glycolysis	Lyase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"brain: 119.2"	"Cell line enhanced"	"Detected in many"		"U-87 MG: 81.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"gdT-cell: 8.2;MAIT T-cell: 9.7;memory B-cell: 5.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 9.6;naive B-cell: 3.3;naive CD4 T-cell: 7.1;naive CD8 T-cell: 7.4;neutrophil: 6.2;T-reg: 5.5"	"Group enriched"	"Detected in many"	7	"B-cells: 5.6;granulocytes: 6.2;T-cells: 10.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000063, HPA068284, HPA068721, CAB073539, CAB079023"	Enhanced	Supported	Supported	"Plasma membrane,Cytosol"			89000000	"Plasma membrane, Cytosol"		"CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: "	"unprognostic (8.96e-2)"	"unprognostic (8.28e-2)"	"prognostic unfavourable (6.96e-4)"	"unprognostic (1.28e-1)"	"unprognostic (7.95e-3)"	"unprognostic (1.39e-2)"	"prognostic unfavourable (5.15e-4)"	"unprognostic (1.48e-1)"	"unprognostic (9.43e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.98e-1)"	"unprognostic (2.02e-2)"	"prognostic unfavourable (7.89e-11)"	"unprognostic (7.61e-2)"	"unprognostic (3.06e-1)"	"unprognostic (8.10e-3)"	"unprognostic (1.24e-1)"	4.2	20.7	31.2	8.3	48.0	4.0	4.9	115.2	119.2	7.6	7.9	10.9	2.6	4.9	11.7	6.3	5.9	9.4	8.0	10.3	30.2	39.2	3.5	2.0	10.1	10.5	29.6	47.4	3.7	4.1	19.1	15.5	4.8	47.7	8.0	7.4	28.6	3.1	15.3	2.1	5.8	6.0	15.2	15.7	5.8	6.4	3.2	13.3	1.7	14.2	0.3	10.3	7.1	5.0	5.6	1.0	6.2	0.2	0.4	10.8	4.5	14.0	8.9	3.2	0.1	4.8	5.2	0.2	10.9	7.0	16.2	25.0	1.7	1.1	19.8	1.8	4.7	2.1	33.7	3.0	24.6	39.6	3.1	27.3	9.1	11.8	3.5	1.6	32.9	2.6	0.1	11.9	2.4	3.4	1.8	0.2	10.8	1.9	12.8	1.7	17.1	5.0	14.2	2.7	4.3	7.9	1.9	25.9	18.2	2.8	0.2	18.6	0.9	0.8	4.3	14.2	15.0	19.1	14.1	14.5	14.5	2.9	81.3	0.0	2.9	1.3	0.0	0.1	8.2	0.0	9.7	5.6	10.8	9.6	0.0	3.3	7.1	7.4	6.2	0.4	0.2	1.0	5.5	4.5	31.2	48.0	115.2	91.3	30.2	39.2	29.6	47.4	47.7	13.3
ENO3		ENSG00000108515	"Enolase 3"	P13929	17	4948092-4957131	"Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Glycolysis	Lyase	"Disease mutation, Glycogen storage disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	12	"skeletal muscle: 638.2;tongue: 320.3"	"Group enriched"	"Detected in many"	4	"HDLM-2: 70.1;HeLa: 30.0;HMC-1: 29.6;RH-30: 48.2;RPMI-8226: 25.2"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA000793, HPA068284, HPA068721"	Enhanced		Supported	"Plasma membrane,Cytosol"			100000000	"Plasma membrane, Cytosol"		"HPA000793: AB_1078742, HPA068284: , HPA068721: "	"unprognostic (7.35e-2)"	"unprognostic (5.25e-2)"	"prognostic unfavourable (7.33e-4)"	"unprognostic (1.57e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.86e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.08e-2)"	"unprognostic (8.12e-2)"	"unprognostic (1.42e-1)"	"unprognostic (6.04e-3)"	"unprognostic (2.21e-2)"	"unprognostic (4.63e-2)"	"unprognostic (5.34e-2)"	"unprognostic (3.48e-1)"	"unprognostic (2.15e-1)"	"unprognostic (4.50e-2)"	7.6	0.3	0.2	0.6	0.2	0.7	0.5	0.6	0.2	0.2	0.4	0.0	0.1	0.8	0.4	8.5	8.6	0.4	0.1	38.3	0.2	0.1	0.5	5.0	0.4	0.5	0.2	0.0	0.4	0.3	0.3	0.5	0.2	0.1	2.1	0.1	1.2	11.8	0.1	638.2	0.3	0.7	0.4	0.2	0.8	0.4	0.5	0.0	0.6	4.8	320.3	10.5	0.3	0.3	13.3	21.0	27.1	24.8	18.5	23.3	36.0	2.8	6.2	2.8	2.6	2.4	0.6	6.8	5.0	0.6	0.3	0.3	3.0	1.9	5.2	6.8	0.4	3.6	1.0	0.4	0.2	70.1	5.7	5.1	30.0	4.4	0.9	1.5	29.6	4.1	1.0	0.5	1.0	0.3	2.3	9.7	1.5	1.5	1.8	6.2	3.6	2.6	8.3	48.2	25.2	0.7	1.9	1.8	6.8	3.2	2.8	3.6	2.5	1.6	1.5	3.0	5.5	1.3	3.7	6.9	3.8	4.3	1.7	5.0	2.9	13.5	15.6	27.1	21.8	22.5	14.7	13.3	18.7	20.3	21.0	11.1	12.3	19.7	19.7	18.5	24.8	16.6	23.3	36.0	0.2	0.2	0.6	0.2	0.2	0.1	0.2	0.0	0.1	0.0
ENO4	"AC023283.3, C10orf134"	ENSG00000188316	"Enolase family member 4"	A6NNW6	10	116849512-116911788	"Enzymes, Predicted intracellular proteins"	Glycolysis	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 12.1;epididymis: 12.6;fallopian tube: 13.6"	"Cell line enhanced"	"Detected in some"		"HaCaT: 2.6;MCF7: 8.2;T-47d: 5.1"	"Low cancer specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"naive B-cell: 1.8"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA037937, HPA037938"	Enhanced		Approved	Nucleoplasm,Mitochondria				Mitochondria	Nucleoplasm	"HPA037937: AB_10697089, HPA037938: "	"unprognostic (2.92e-3)"	"unprognostic (1.39e-1)"	"unprognostic (1.07e-1)"	"unprognostic (6.55e-4)"	"unprognostic (8.38e-5)"	"unprognostic (1.88e-1)"	"unprognostic (2.21e-1)"	"unprognostic (5.18e-2)"	"unprognostic (1.22e-1)"	"unprognostic (2.23e-2)"	"unprognostic (3.74e-3)"	"unprognostic (2.06e-1)"	"unprognostic (2.20e-3)"	"unprognostic (1.18e-1)"	"unprognostic (9.77e-3)"	"unprognostic (9.87e-5)"	"unprognostic (1.08e-2)"	0.7	2.1	4.3	0.6	4.3	0.2	2.2	2.6	3.6	1.7	1.0	8.0	0.9	0.3	4.3	12.6	1.4	13.6	1.3	0.5	6.4	4.7	2.3	2.7	3.9	1.2	4.1	4.8	4.2	3.2	3.7	3.4	0.5	12.1	2.1	0.8	3.0	1.6	1.2	0.2	1.1	0.5	0.9	4.4	0.5	0.8	8.8	1.9	0.2	4.2	0.0	0.6	1.8	0.5	1.8	1.0	0.0	0.6	0.0	1.2	0.1	1.4	0.5	0.5	0.1	0.0	0.0	0.0	0.0	0.7	0.6	0.0	0.3	1.1	0.0	0.9	2.0	2.6	0.0	0.7	0.8	0.0	1.5	0.0	1.0	0.3	0.0	0.0	0.0	0.1	0.6	0.6	0.0	0.1	0.1	0.0	0.7	8.2	0.0	0.0	1.4	0.2	0.0	0.0	0.0	1.1	0.6	0.9	0.0	2.1	0.1	0.0	5.1	0.0	0.5	0.0	0.7	0.4	1.1	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.6	0.0	0.0	0.4	0.0	1.6	0.2	0.0	0.3	1.8	0.2	0.0	0.0	0.0	0.2	1.0	1.2	0.1	4.3	4.3	2.6	3.6	6.4	4.7	4.1	4.8	12.1	1.9
ENOSF1	"HSRTSBETA, rTS, TYMSAS"	ENSG00000132199	"Enolase superfamily member 1"	Q7L5Y1	18	670324-712676	"Enzymes, Predicted intracellular proteins"		"Isomerase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA047829	Enhanced									"HPA047829: "	"prognostic favourable (2.27e-4)"	"unprognostic (8.03e-2)"	"unprognostic (2.02e-2)"	"unprognostic (7.87e-3)"	"unprognostic (1.85e-1)"	"unprognostic (4.29e-2)"	"unprognostic (6.48e-3)"	"unprognostic (1.55e-2)"	"unprognostic (3.50e-3)"	"unprognostic (1.33e-3)"	"unprognostic (2.44e-2)"	"unprognostic (5.07e-3)"	"unprognostic (8.02e-2)"	"unprognostic (1.72e-1)"	"unprognostic (1.36e-1)"	"unprognostic (5.03e-2)"	"unprognostic (1.31e-2)"	8.5	22.0	5.4	11.7	9.4	11.0	10.7	2.2	7.6	12.3	12.7	26.1	15.9	12.1	11.8	10.9	10.4	10.4	11.6	10.0	6.3	5.6	36.7	26.0	15.0	10.4	10.2	6.0	9.6	13.3	13.1	19.8	8.9	12.3	16.3	11.5	18.4	16.4	19.6	9.9	8.3	13.8	14.6	7.0	10.1	12.3	6.5	9.8	12.7	21.2	7.8	8.3	8.8	7.7	2.3	4.3	2.4	3.4	2.9	7.0	2.5	4.1	13.9	7.4	6.6	3.8	3.1	5.3	5.8	7.1	3.7	5.4	12.6	12.0	6.9	1.9	5.4	3.2	9.6	8.3	2.7	3.2	5.0	11.1	15.9	7.3	13.5	19.6	2.8	5.9	9.4	3.7	6.4	8.0	7.6	7.0	5.6	12.5	11.9	6.0	5.9	7.6	5.9	1.8	18.8	11.0	18.1	8.4	3.0	13.8	11.9	2.6	4.0	14.2	6.5	1.9	5.1	8.7	1.8	12.8	11.3	11.2	15.1	7.8	2.6	0.0	1.6	2.4	7.0	3.4	6.9	2.3	4.9	4.1	2.5	0.8	6.9	5.6	0.1	2.9	1.6	4.3	3.4	2.5	5.4	9.4	2.2	7.6	6.3	5.6	10.2	6.0	12.3	9.8
ETNPPL	AGXT2L1	ENSG00000164089	"Ethanolamine-phosphate phospho-lyase"	Q8TBG4	4	108742040-108763054	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"brain: 53.5;liver: 111.0"	"Cell line enhanced"	"Detected in some"		"HeLa: 10.8;Hep G2: 4.2;NTERA-2: 2.2"	"Group enriched"	"Detected in some"	23	"glioma: 7.9;liver cancer: 21.7"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044546, HPA072938"	Approved		Approved	Nucleoplasm				Nucleoplasm		"HPA044546: AB_10962867, HPA072938: "	"unprognostic (5.20e-3)"	"unprognostic (1.33e-1)"		"unprognostic (3.93e-1)"	"prognostic favourable (9.52e-5)"		"unprognostic (5.93e-3)"	"unprognostic (3.91e-2)"	"unprognostic (2.82e-1)"	"unprognostic (6.32e-2)"	"unprognostic (2.70e-2)"	"unprognostic (1.30e-1)"	"unprognostic (3.40e-2)"	"unprognostic (1.93e-1)"	"unprognostic (1.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (9.48e-2)"	1.2	1.9	50.8	1.3	51.3	1.2	1.3	7.9	53.5	1.3	1.2	13.4	0.0	1.3	1.4	1.2	1.3	1.2	1.4	3.2	37.5	20.1	6.2	111.0	1.2	1.2	26.0	28.7	1.3	1.2	1.4	0.1	1.2	15.7	1.2	1.2	0.5	19.9	1.3	1.6	1.2	1.2	1.2	7.3	1.6	10.4	1.5	18.7	0.0	1.9	0.0	1.2	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.0	0.1	10.8	4.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.5	0.0	2.2	0.5	0.0	0.1	0.0	0.0	0.0	1.1	0.0	0.3	0.0	0.9	0.2	0.0	0.1	0.0	0.4	0.0	0.1	0.0	0.0	0.1	0.1	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	50.8	51.3	7.9	24.9	37.5	20.1	26.0	28.7	15.7	18.7
FAHD1	"C16orf36, DKFZP566J2046"	ENSG00000180185	"Fumarylacetoacetate hydrolase domain containing 1"	Q6P587	16	1826941-1840207	"Enzymes, Predicted intracellular proteins"		"Hydrolase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025530, HPA043226, HPA043534"	Enhanced		Enhanced	Nucleoplasm,Mitochondria				Mitochondria	Nucleoplasm	"CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535"	"unprognostic (3.71e-1)"	"unprognostic (1.25e-2)"	"prognostic favourable (8.27e-4)"	"unprognostic (1.99e-1)"	"unprognostic (6.74e-2)"	"unprognostic (1.01e-3)"	"unprognostic (2.89e-2)"	"unprognostic (4.32e-1)"	"unprognostic (1.13e-1)"	"unprognostic (5.36e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.38e-1)"	"prognostic favourable (2.80e-14)"	"unprognostic (1.02e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.26e-1)"	"unprognostic (3.31e-2)"	10.4	17.0	10.4	6.7	9.9	6.5	9.2	8.6	12.7	6.8	21.7	9.3	8.2	26.7	9.8	10.9	14.8	5.8	10.2	15.8	10.9	11.4	46.8	43.6	5.6	5.2	10.1	9.4	7.9	17.4	9.0	11.1	10.4	9.9	8.1	11.1	8.5	9.1	9.8	20.2	12.4	24.8	6.9	8.8	6.3	14.9	6.9	9.5	4.7	12.5	19.0	5.7	9.9	7.9	18.5	23.1	8.6	27.5	19.6	16.0	13.7	8.3	18.8	9.0	15.8	12.0	8.7	5.6	13.7	6.8	9.2	10.1	12.0	8.7	5.3	11.6	8.5	17.2	7.0	11.0	8.3	8.0	16.6	4.8	16.2	27.6	11.7	8.2	9.2	11.4	14.5	8.4	5.6	11.9	4.9	5.6	11.5	38.2	4.4	12.5	5.3	14.1	10.2	12.2	15.0	32.9	10.5	17.6	14.6	17.9	14.4	21.5	21.2	5.6	17.4	15.1	10.8	8.8	7.4	8.1	17.0	6.3	9.6	6.0	6.4	6.5	23.5	8.6	14.4	27.5	13.0	18.5	14.5	15.7	23.1	16.9	16.0	14.9	2.0	19.6	19.1	17.9	14.7	13.7	10.4	9.9	8.6	12.7	10.9	11.4	10.1	9.4	9.9	9.5
FASN	"FAS, SDR27X1"	ENSG00000169710	"Fatty acid synthase"	P49327	17	82078333-82098332	"Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	"Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 147.6"	"Cell line enhanced"	"Detected in many"		"SK-BR-3: 152.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005192, HPA006461, CAB015417, HPA056108"	Enhanced		Enhanced	"Plasma membrane,Cytosol"			1600000	"Plasma membrane, Cytosol"		"CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039"	"unprognostic (3.35e-2)"	"prognostic unfavourable (1.42e-5)"	"unprognostic (9.69e-3)"	"unprognostic (4.09e-2)"	"unprognostic (3.46e-3)"	"unprognostic (1.55e-2)"	"unprognostic (3.09e-2)"	"unprognostic (4.74e-3)"	"unprognostic (3.15e-1)"	"unprognostic (3.15e-1)"	"unprognostic (2.87e-3)"	"unprognostic (1.05e-1)"	"prognostic unfavourable (7.16e-5)"	"unprognostic (4.50e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.35e-2)"	"unprognostic (7.03e-3)"	147.6	7.8	8.2	14.2	11.5	11.1	57.5	19.1	23.0	6.6	27.7	17.0	14.1	8.2	4.7	14.2	17.1	4.3	19.4	6.3	7.9	6.7	3.7	30.8	26.8	9.8	7.3	11.5	6.4	10.4	6.7	15.3	8.4	21.7	28.8	3.4	7.6	16.9	10.8	7.5	17.2	6.5	4.6	8.4	5.1	11.9	6.6	8.8	1.9	5.1	10.7	5.4	8.0	6.6	0.5	1.4	0.0	0.8	0.2	1.9	0.8	23.1	24.3	11.3	7.8	18.3	12.4	24.2	4.6	6.0	4.9	9.0	25.4	15.8	7.7	3.8	3.5	19.4	10.9	21.3	0.9	3.6	47.4	16.0	18.2	33.9	5.2	8.6	2.4	11.9	5.6	12.5	2.9	5.5	24.1	6.9	1.7	40.1	9.4	13.7	21.9	14.2	8.3	6.4	15.3	5.5	29.7	28.1	15.6	6.8	152.8	12.4	27.2	16.5	9.6	7.2	14.8	5.9	11.0	9.3	2.0	8.0	4.3	9.4	10.6	0.0	0.8	0.0	1.2	0.5	0.7	0.5	1.9	1.4	1.4	0.2	0.7	0.6	0.0	0.2	0.4	1.1	0.6	0.8	8.2	11.5	19.1	23.0	7.9	6.7	7.3	11.5	21.7	8.8
FECH		ENSG00000066926	Ferrochelatase	P22830	18	57548283-57586772	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 87.9"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044100, HPA048177"	Approved									"HPA044100: , HPA048177: "	"unprognostic (2.30e-1)"	"unprognostic (3.17e-2)"	"unprognostic (4.59e-3)"	"unprognostic (6.85e-2)"	"unprognostic (7.60e-2)"	"unprognostic (1.08e-1)"	"unprognostic (3.86e-2)"	"unprognostic (3.34e-2)"	"unprognostic (2.85e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.92e-1)"	"unprognostic (2.36e-1)"	"prognostic favourable (2.38e-10)"	"unprognostic (1.10e-1)"	"unprognostic (8.30e-2)"	"unprognostic (4.05e-3)"	"unprognostic (3.58e-2)"	10.0	18.0	9.9	6.5	14.1	87.9	9.9	7.9	17.4	7.9	9.5	23.1	8.0	7.6	10.5	7.9	13.6	8.5	6.9	17.6	10.4	9.7	28.2	28.3	7.2	9.8	12.0	13.9	9.1	9.5	11.4	8.8	14.8	15.6	14.5	9.3	12.1	10.1	11.1	36.2	8.6	7.2	12.3	11.7	10.6	8.5	5.8	13.1	18.4	11.6	10.8	7.1	12.1	8.8	4.2	12.4	14.9	10.9	13.8	9.3	9.1	7.3	20.0	7.4	11.9	4.7	10.8	13.0	10.5	10.7	15.2	13.6	5.3	6.7	3.3	10.8	14.4	9.4	10.9	8.8	12.3	19.2	11.6	24.3	13.9	11.0	12.1	16.9	44.4	11.2	9.4	9.4	4.3	11.4	34.5	13.9	8.5	8.7	17.6	3.5	5.6	8.7	12.6	10.3	19.8	15.1	13.9	7.4	11.2	13.6	14.6	6.2	13.9	7.1	9.0	5.3	7.0	2.1	7.6	40.6	17.4	7.1	8.6	8.3	8.9	14.0	9.6	14.9	9.3	10.9	6.7	4.2	5.7	8.3	12.4	2.6	4.2	5.9	0.7	13.8	10.2	9.5	5.9	9.1	9.9	14.1	7.9	17.4	10.4	9.7	12.0	13.9	15.6	13.1
FH	fumarase	ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519761	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease mutation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 93.4"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria			2800000	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favourable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	14.3	28.1	15.7	10.4	20.2	9.3	13.3	15.7	24.4	10.5	22.7	9.9	16.7	23.2	13.7	10.7	17.7	10.3	9.5	59.0	22.9	13.9	35.0	93.4	9.9	13.3	15.2	19.4	9.4	13.9	25.2	11.4	14.3	18.4	12.3	24.4	10.2	18.4	20.6	65.1	13.4	21.4	14.7	14.4	11.1	17.5	14.0	11.7	13.8	12.3	45.2	13.4	13.4	11.2	16.0	26.4	4.5	18.8	10.4	13.9	8.9	29.2	24.5	23.3	21.0	22.9	27.0	36.9	36.3	28.5	41.0	25.8	35.1	18.3	18.6	24.1	27.8	41.7	35.6	27.0	35.8	21.2	11.5	17.4	26.0	29.9	20.5	40.7	15.9	19.5	16.8	23.0	26.0	25.2	53.0	24.1	29.8	14.6	35.1	27.2	24.7	52.7	29.0	25.5	83.5	39.5	24.9	30.0	25.9	30.6	36.3	23.2	27.6	27.7	24.7	18.4	23.8	32.5	60.5	21.6	23.1	22.6	20.6	46.8	26.4	4.5	12.8	2.7	9.7	18.8	12.6	16.0	11.4	9.0	26.4	14.1	13.9	12.7	0.7	10.4	15.7	13.2	13.2	8.9	15.7	20.2	15.7	24.4	22.9	13.9	15.2	19.4	18.4	11.7
FTCD		ENSG00000160282	"Formimidoyltransferase cyclodeaminase"	O95954	21	46136262-46155567	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Histidine metabolism"	"Lyase, Multifunctional enzyme, Transferase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"liver: 126.8"	"Cell line enriched"	"Detected in some"	29	"Hep G2: 44.4"	"Cancer enriched"	"Detected in some"	8	"liver cancer: 87.3"	"Low region specificity"	"Detected in single"			"Cell type enhanced"	"Detected in single"		"T-reg: 2.5"	"Lineage enriched"	"Detected in single"	25	"T-cells: 2.5"									"HPA020073, HPA030928, HPA030929, HPA036114"	Enhanced		Approved	"Plasma membrane,Cytosol"			580000	Cytosol	"Plasma membrane"	"HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947"	"unprognostic (1.71e-1)"	"unprognostic (2.27e-1)"	"unprognostic (4.62e-5)"	"unprognostic (2.90e-2)"	"unprognostic (1.13e-1)"	"unprognostic (2.96e-1)"	"prognostic favourable (1.70e-4)"	"unprognostic (1.85e-1)"	"unprognostic (2.67e-1)"	"unprognostic (1.99e-1)"	"prognostic favourable (6.78e-5)"	"unprognostic (1.80e-1)"	"prognostic favourable (5.78e-4)"	"unprognostic (3.80e-2)"	"unprognostic (3.60e-1)"	"unprognostic (9.37e-2)"	"unprognostic (2.10e-1)"	0.2	0.0	0.6	0.2	1.6	0.0	0.2	0.2	0.7	0.2	0.3	0.2	0.2	0.3	0.2	2.0	0.2	0.0	0.2	0.2	0.5	0.4	25.9	126.8	0.2	0.2	0.4	0.2	0.2	1.0	0.0	0.2	0.2	0.2	0.3	0.0	0.2	0.2	0.2	0.2	0.0	0.4	0.2	0.2	0.2	0.1	1.5	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.0	0.0	0.0	0.0	0.0	2.5	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.0	44.4	0.0	0.2	0.1	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.0	0.3	0.0	0.0	0.9	0.0	0.1	0.1	0.0	0.1	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.2	0.0	0.1	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.5	0.5	0.0	0.0	0.5	0.7	0.0	0.0	0.0	0.0	2.5	0.1	0.6	1.6	0.2	0.7	0.5	0.4	0.4	0.2	0.2	0.2
GAD1	GAD	ENSG00000128683	"Glutamate decarboxylase 1"	Q99259	2	170813213-170861151	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Neurotransmitter biosynthesis"	"Decarboxylase, Lyase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"brain: 53.9"	"Cell line enhanced"	"Detected in many"		"HaCaT: 10.5;HEL: 34.2"	"Cancer enhanced"	"Detected in many"		"endometrial cancer: 4.4"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Region enriched"	"Detected in all"	4	"olfactory region: 888.9"	"CAB004415, HPA031949, HPA058412, CAB078176"	Enhanced	Supported	Approved	Vesicles				Vesicles		"CAB004415: AB_627650, CAB078176: , HPA031949: , HPA058412: "	"unprognostic (1.28e-1)"	"prognostic favourable (7.31e-4)"	"unprognostic (1.87e-2)"	"prognostic favourable (8.61e-4)"	"unprognostic (1.12e-1)"	"unprognostic (3.05e-1)"	"unprognostic (4.97e-7)"	"unprognostic (1.51e-1)"	"unprognostic (7.72e-2)"	"unprognostic (4.27e-4)"	"unprognostic (6.75e-2)"	"unprognostic (9.18e-3)"	"unprognostic (6.90e-5)"	"unprognostic (2.93e-2)"	"unprognostic (6.57e-2)"	"unprognostic (1.56e-2)"	"unprognostic (3.08e-3)"	1.2	2.0	14.5	0.9	28.1	3.7	1.0	10.6	53.9	1.8	1.0	3.1	0.0	1.0	2.6	5.5	1.2	1.1	1.0	1.0	10.8	24.4	6.0	1.0	1.1	1.1	8.6	17.5	1.1	1.1	9.5	2.8	1.4	6.0	1.8	1.0	1.3	1.0	1.3	0.9	1.0	1.1	1.0	2.6	1.0	1.0	4.0	3.4	0.0	1.1	0.0	1.2	1.5	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.7	0.3	0.0	3.7	0.0	0.0	0.0	0.2	0.0	1.4	0.9	2.5	3.5	0.0	0.5	0.2	10.5	1.2	0.3	0.8	1.4	7.2	34.2	3.0	0.1	0.0	0.1	0.6	0.0	3.1	0.0	1.2	0.0	8.8	0.1	0.4	0.8	0.0	0.0	4.2	3.7	0.5	2.5	0.2	4.6	4.9	3.6	1.1	6.5	0.0	1.8	0.1	0.0	0.0	6.4	0.9	1.3	3.7	0.0	0.0	0.0	6.2	1.7	8.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	14.5	28.1	10.6	36.7	10.8	24.4	8.6	17.5	6.0	3.4
GAD2	GAD65	ENSG00000136750	"Glutamate decarboxylase 2"	Q05329	10	26216307-26304558	"Enzymes, Predicted intracellular proteins"	"Neurotransmitter biosynthesis"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"brain: 66.2"	"Group enriched"	"Detected in some"	12	"MOLT-4: 5.0;SCLC-21H: 11.4"	"Group enriched"	"Detected in some"	21	"glioma: 0.7;pancreatic cancer: 3.0;testis cancer: 1.2"	"Region enhanced"	"Detected in all"		"basal ganglia: 66.2"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044637, CAB078177"	Enhanced									"CAB078177: , HPA044637: AB_10794053"		"unprognostic (8.67e-2)"			"unprognostic (1.11e-1)"						"unprognostic (4.93e-2)"		"unprognostic (2.52e-5)"	"unprognostic (5.44e-2)"	"unprognostic (8.08e-2)"			1.0	0.9	6.3	0.9	66.2	1.0	0.9	5.6	28.7	0.9	0.9	1.4	0.0	1.2	0.9	1.1	0.9	0.9	0.9	0.9	5.2	13.2	1.0	0.9	0.9	0.9	5.4	10.0	0.9	12.9	0.9	0.4	0.9	6.8	1.2	1.0	0.0	0.9	0.9	0.9	1.3	1.1	0.9	1.3	0.9	1.2	1.7	8.1	0.0	0.9	0.0	0.9	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	5.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	11.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	6.3	66.2	5.6	18.2	5.2	13.2	5.4	10.0	6.8	8.1
GADL1		ENSG00000144644	"Glutamate decarboxylase like 1"	Q6ZQY3	3	30726200-30894765	"Enzymes, Predicted intracellular proteins"		"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"		"Tissue enriched"	"Detected in many"	6	"skeletal muscle: 21.6"	"Cell line enhanced"	"Detected in many"		"HAP1: 9.7"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA039160, HPA040229"	Uncertain		Approved	"Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"		"HPA039160: AB_10796222, HPA040229: AB_10796118"	"unprognostic (4.96e-2)"	"unprognostic (1.30e-2)"	"unprognostic (9.83e-2)"	"unprognostic (1.39e-2)"	"unprognostic (5.60e-2)"	"unprognostic (7.32e-2)"		"unprognostic (5.05e-3)"	"unprognostic (8.37e-2)"	"unprognostic (1.23e-2)"	"unprognostic (2.02e-3)"	"unprognostic (1.63e-1)"	"unprognostic (1.98e-5)"	"unprognostic (8.81e-2)"	"unprognostic (4.54e-2)"	"unprognostic (4.39e-1)"	"unprognostic (1.06e-1)"	0.5	0.3	0.2	0.2	0.3	1.0	0.4	0.5	0.7	0.4	0.2	0.0	0.0	0.1	0.2	1.6	1.4	0.2	2.0	2.3	0.2	0.3	0.7	0.2	1.6	0.3	0.3	0.8	0.5	0.3	0.1	0.6	0.5	2.1	0.5	0.1	0.3	0.3	0.0	21.6	0.8	0.2	2.5	0.7	0.5	0.2	1.1	0.0	0.0	1.2	3.3	0.7	0.5	0.3	1.7	0.5	1.9	0.8	0.5	1.3	0.3	1.3	0.3	0.8	1.1	0.9	0.5	1.5	0.6	0.3	0.3	0.2	1.3	1.2	1.1	0.5	0.2	0.9	9.7	0.3	0.4	1.7	0.5	1.6	1.5	0.5	0.4	0.9	3.3	0.4	0.5	0.7	0.3	0.6	1.2	4.0	0.9	1.1	0.6	1.3	1.8	0.5	1.9	2.1	1.0	1.0	1.5	1.1	0.9	1.1	0.7	2.9	1.1	0.8	5.0	1.5	1.4	1.9	0.7	1.6	0.8	0.7	0.6	0.9	1.9	1.9	0.7	0.8	1.0	0.6	0.8	1.2	0.9	0.6	0.4	1.7	1.1	1.0	1.7	0.5	0.8	0.5	1.3	0.3	0.2	0.3	0.5	0.7	0.2	0.3	0.3	0.8	2.1	0.0
GGACT	A2LD1	ENSG00000134864	"Gamma-glutamylamine cyclotransferase"	Q9BVM4	13	100530164-100589528	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 47.0"	"Cell line enriched"	"Detected in many"	5	"SCLC-21H: 54.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA065320	Enhanced						75000			"HPA065320: "	"unprognostic (1.93e-1)"	"unprognostic (5.33e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.30e-3)"	"unprognostic (9.12e-3)"	"unprognostic (1.64e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.07e-2)"	"unprognostic (7.41e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.03e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.95e-2)"	"unprognostic (3.09e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.37e-2)"	"unprognostic (2.57e-1)"	3.6	6.6	3.2	3.4	3.4	0.9	3.4	2.6	4.5	2.0	4.9	3.6	1.7	5.7	4.0	3.4	2.8	2.5	5.5	1.7	2.6	2.2	47.0	10.9	2.4	4.6	3.5	2.1	2.5	9.8	1.8	1.9	2.1	4.4	2.4	3.4	4.1	12.0	14.2	2.7	3.1	6.7	3.4	4.3	6.1	4.4	11.0	3.3	3.7	2.5	5.0	6.4	2.5	2.5	5.2	4.2	1.0	7.5	8.0	8.3	4.2	5.5	0.7	4.5	4.9	3.9	6.0	1.9	3.5	0.9	0.6	1.5	0.0	5.0	0.5	2.0	2.5	0.3	0.7	1.0	0.2	7.7	3.0	2.3	0.4	0.2	5.5	3.3	7.7	7.1	4.0	0.1	0.3	2.3	1.1	0.1	0.9	0.3	0.5	0.4	0.2	1.5	0.3	1.1	0.6	5.6	0.9	54.1	2.0	1.1	2.5	2.5	2.3	11.0	2.1	0.0	0.0	1.2	0.9	2.9	1.6	0.2	0.3	2.5	2.5	0.0	5.1	1.0	7.9	7.2	7.3	5.2	6.4	8.3	4.2	5.0	4.0	5.9	0.0	8.0	7.5	3.0	6.5	4.2	3.2	3.4	2.6	4.5	2.6	2.2	3.5	2.1	4.4	3.3
GGCT	"C7orf24, CRF21, GCTG, Ggc, MGC3077"	ENSG00000006625	Gamma-glutamylcyclotransferase	O75223	7	30496621-30504844	"Enzymes, Plasma proteins, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"											"HPA020735, HPA029914"	Approved						2400000			"HPA020735: AB_1845754, HPA029914: AB_10602321"	"prognostic unfavourable (7.68e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.51e-2)"	"unprognostic (2.62e-1)"	"unprognostic (2.54e-3)"	"unprognostic (5.80e-2)"	"prognostic unfavourable (7.23e-4)"	"unprognostic (1.33e-3)"	"unprognostic (2.19e-2)"	"unprognostic (6.42e-3)"	"unprognostic (2.66e-3)"	"unprognostic (1.68e-1)"	"unprognostic (2.27e-2)"	"unprognostic (1.19e-1)"	"unprognostic (8.12e-3)"	"unprognostic (2.00e-3)"	"unprognostic (9.92e-2)"	30.8	18.6	15.5	14.5	15.9	10.2	26.4	10.8	25.6	12.6	20.2	7.3	19.3	16.7	10.4	59.6	33.4	13.5	22.5	12.2	14.6	12.4	22.0	18.7	14.6	13.6	11.6	14.4	15.2	17.2	14.9	11.4	18.5	15.0	14.3	21.9	8.0	23.9	19.2	12.6	29.8	16.8	14.2	9.9	13.2	13.3	8.1	5.8	11.0	28.7	32.1	18.9	17.4	19.1	14.8	21.7	5.6	12.8	15.3	16.4	10.1	40.2	10.6	17.2	23.2	7.3	13.3	20.1	13.8	5.4	13.3	16.1	14.0	14.1	26.0	9.1	5.1	51.4	18.1	14.4	17.4	4.9	20.0	18.4	21.4	18.4	9.5	30.9	14.3	12.9	11.6	13.8	17.9	13.4	26.1	15.0	10.4	22.2	18.7	41.8	24.9	17.1	18.8	20.0	25.9	12.7	36.8	21.9	22.1	12.3	77.4	14.7	49.6	29.3	8.0	8.7	16.4	16.5	26.8	11.1	26.1	20.1	6.8	42.0	16.2	5.6	12.8	4.2	9.6	12.5	13.3	14.8	12.7	12.3	21.7	11.7	12.3	11.9	0.7	15.3	7.3	19.1	16.4	10.1	15.5	15.9	10.8	25.6	14.6	12.4	11.6	14.4	15.0	5.8
GGCX	VKCFD1	ENSG00000115486	"Gamma-glutamyl carboxylase"	P38435	2	85544723-85561547	"Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins"		Lyase	"Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	5	"liver: 74.8"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA018284	Approved									"HPA018284: AB_1849641"	"unprognostic (4.88e-3)"	"unprognostic (1.13e-2)"	"unprognostic (1.22e-2)"	"prognostic unfavourable (1.82e-6)"	"unprognostic (5.67e-2)"	"unprognostic (1.85e-3)"	"unprognostic (2.96e-2)"	"unprognostic (3.77e-2)"	"unprognostic (5.64e-2)"	"unprognostic (2.18e-2)"	"unprognostic (6.45e-3)"	"unprognostic (5.23e-2)"	"unprognostic (8.17e-3)"	"unprognostic (7.85e-2)"	"unprognostic (2.59e-1)"	"unprognostic (7.63e-3)"	"unprognostic (9.38e-2)"	7.1	7.8	4.8	4.2	6.3	1.6	10.8	6.3	6.6	6.4	4.9	5.4	8.3	4.0	6.3	8.1	6.5	5.9	7.0	6.8	5.4	3.6	9.0	74.8	8.1	5.4	5.4	5.0	7.0	11.4	15.1	5.6	13.8	5.9	6.3	5.5	5.8	7.4	7.9	6.8	4.9	5.5	7.2	5.1	4.5	6.0	3.6	5.7	3.4	8.5	5.3	5.4	7.3	6.0	0.9	4.9	6.0	7.2	2.2	3.2	3.2	6.8	11.1	7.9	8.8	40.0	11.4	17.6	12.2	14.4	9.0	12.8	19.0	8.4	2.4	12.5	20.0	11.1	5.6	15.4	10.0	4.3	7.7	4.4	7.4	18.0	14.9	2.7	4.2	14.1	9.1	18.2	12.5	12.7	5.3	3.6	26.1	8.9	1.4	2.1	3.7	9.6	2.6	18.6	6.1	12.5	13.1	3.0	5.0	10.9	21.6	11.3	10.5	2.7	11.6	11.6	10.2	11.2	8.3	2.8	7.8	2.0	11.1	2.8	16.2	6.0	7.2	3.6	3.2	7.2	3.0	0.7	1.3	1.2	4.9	0.9	3.2	3.0	3.2	2.2	4.4	4.0	1.9	3.2	4.8	6.3	6.3	6.6	5.4	3.6	5.4	5.0	5.9	5.7
GLO1	GLOD1	ENSG00000124767	"Glyoxalase I"	Q04760	6	38675925-38703141	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"		Lyase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enriched"	"Detected in all"	4	"HMC-1: 244.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB040541, CAB040542, HPA059791"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Cytosol"			1600000	"Nucleoplasm, Plasma membrane, Cytosol"		"CAB040541: , CAB040542: , HPA059791: "	"unprognostic (4.33e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.37e-2)"	"unprognostic (1.08e-2)"	"unprognostic (3.96e-3)"	"unprognostic (2.51e-1)"	"prognostic unfavourable (5.21e-4)"	"unprognostic (5.09e-2)"	"unprognostic (2.10e-2)"	"unprognostic (1.28e-2)"	"unprognostic (2.61e-2)"	"unprognostic (8.71e-2)"	"unprognostic (1.20e-2)"	"unprognostic (9.29e-2)"	"unprognostic (1.83e-1)"	"unprognostic (2.54e-1)"	"unprognostic (6.21e-2)"	22.2	30.5	42.1	19.5	42.3	11.4	32.0	25.4	42.3	27.1	42.1	19.7	22.9	48.1	25.3	49.2	28.2	31.5	17.8	39.2	37.8	37.7	37.1	65.3	30.7	31.6	38.9	29.7	37.6	25.9	33.2	12.6	26.7	40.6	74.0	22.7	21.7	21.7	28.2	57.5	31.3	64.3	28.9	37.6	25.6	21.3	12.9	21.4	19.8	32.6	42.5	24.3	28.6	24.7	25.9	28.6	8.5	15.6	10.8	24.4	14.7	18.1	8.4	24.2	24.0	11.5	20.8	21.4	15.8	15.0	22.3	23.2	20.5	7.0	20.2	12.5	12.6	12.0	20.7	20.4	28.3	18.3	32.0	29.9	10.9	19.1	17.3	11.3	244.2	17.7	12.6	21.1	15.1	24.0	23.5	13.4	20.8	15.3	17.7	14.4	17.4	16.5	15.4	29.3	13.2	20.3	13.7	18.9	19.1	11.1	15.5	29.8	18.0	57.1	9.9	17.4	16.0	15.0	25.0	10.6	20.0	55.5	6.3	29.4	27.9	8.5	9.8	6.9	18.0	15.6	24.4	24.7	18.1	18.3	18.3	25.9	17.1	17.9	1.2	10.8	12.1	28.6	15.7	14.7	42.1	42.3	25.4	42.3	37.8	37.7	38.9	29.7	40.6	21.4
GLUL	GLNS	ENSG00000135821	"Glutamate-ammonia ligase"	P15104	1	182381704-182392206	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Angiogenesis	"Ligase, Transferase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 138.5;ASC TERT1: 97.9;HSkMC: 84.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"neutrophil: 92.2"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 92.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007316, HPA007571, CAB008636"	Approved		Supported	Mitochondria,Cytosol			28000	"Mitochondria, Cytosol"		"CAB008636: AB_1616669, HPA007316: AB_1078981, HPA007571: AB_1078980"	"prognostic favourable (4.81e-4)"	"unprognostic (1.52e-3)"	"unprognostic (3.89e-1)"	"unprognostic (3.32e-1)"	"unprognostic (1.25e-1)"	"unprognostic (9.52e-2)"	"unprognostic (7.58e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.26e-1)"	"unprognostic (8.92e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.17e-1)"	"unprognostic (1.38e-2)"	"unprognostic (4.17e-2)"	"unprognostic (2.06e-1)"	"unprognostic (5.55e-2)"	"unprognostic (4.53e-3)"	173.3	19.2	83.7	37.2	91.0	47.6	63.1	48.5	80.7	41.9	20.4	49.9	9.4	6.2	20.5	29.7	54.0	31.6	26.2	23.5	74.0	48.7	15.6	64.9	39.5	36.9	71.0	48.8	66.2	49.0	7.4	8.9	41.8	70.6	17.4	23.3	39.3	30.4	25.5	159.8	27.9	16.4	30.5	51.3	36.1	71.4	24.0	55.2	8.6	63.9	15.5	24.2	34.7	32.2	2.5	11.0	92.2	21.1	3.4	6.3	18.6	2.9	1.2	13.7	0.0	138.5	97.9	10.1	5.0	16.2	3.0	2.7	7.2	3.0	2.5	5.4	9.7	6.8	5.9	35.6	2.5	6.8	16.6	33.5	5.7	14.0	7.3	14.7	26.8	84.6	42.8	3.8	45.4	6.1	28.2	1.5	10.7	1.6	22.9	14.1	10.1	6.4	8.3	3.6	4.3	5.3	13.0	9.4	6.2	1.4	18.3	1.9	17.8	18.7	4.5	0.1	0.2	0.0	1.1	0.5	0.3	0.0	2.6	8.4	0.5	43.6	21.1	54.9	6.3	20.5	2.6	1.6	4.5	5.2	11.0	2.5	2.3	3.9	92.2	3.4	17.1	6.1	1.7	18.6	83.7	91.0	48.5	80.7	74.0	48.7	71.0	48.8	70.6	55.2
GMDS	"GMD, SDR3E1"	ENSG00000112699	"GDP-mannose 4,6-dehydratase"	O60547	6	1623806-2245692	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPMI-8226: 41.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031528	Enhanced						41000			"HPA031528: AB_10601016"	"unprognostic (5.94e-2)"	"unprognostic (3.92e-2)"	"unprognostic (1.12e-1)"	"prognostic favourable (5.89e-4)"	"unprognostic (4.37e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.10e-3)"	"unprognostic (7.15e-2)"	"unprognostic (2.29e-1)"	"unprognostic (8.02e-2)"	"unprognostic (2.38e-1)"	"unprognostic (4.41e-1)"	"prognostic favourable (5.93e-4)"	"unprognostic (2.45e-1)"	"unprognostic (2.84e-1)"	"unprognostic (6.68e-2)"	"unprognostic (1.12e-1)"	5.1	4.0	6.6	29.6	8.7	3.2	7.6	6.0	6.8	12.9	34.9	2.7	10.4	42.1	4.1	6.4	29.2	4.9	38.5	4.9	5.6	4.6	9.3	15.1	7.8	11.8	4.1	3.7	4.3	27.1	19.3	8.9	3.0	4.0	8.6	34.2	6.3	40.4	7.6	3.3	4.9	43.7	4.4	3.1	6.0	38.4	9.0	3.4	9.3	5.6	9.0	19.6	6.1	6.7	10.5	13.9	6.8	12.3	12.0	12.4	7.3	16.9	4.0	2.8	20.1	4.7	12.8	6.9	4.7	9.8	8.8	8.3	8.6	9.9	8.1	14.5	5.1	6.7	8.7	16.6	10.2	11.1	10.6	7.8	4.4	40.7	5.2	12.5	8.7	14.1	5.7	6.9	14.6	10.2	5.0	3.8	5.6	9.7	17.2	14.8	4.3	13.5	9.0	6.5	41.5	21.2	22.4	16.1	3.8	4.3	6.8	10.4	6.3	7.9	4.4	6.8	5.0	6.8	8.3	8.6	12.1	8.6	4.4	8.8	8.9	6.8	12.3	1.4	7.9	7.6	10.6	10.5	9.5	7.8	13.9	5.5	8.3	11.1	3.8	12.0	6.1	5.8	12.4	7.3	6.6	8.7	6.0	6.8	5.6	4.6	4.1	3.7	4.0	3.4
GUCY1A1	"GC-SA3, GUC1A3, GUCY1A3"	ENSG00000164116	"Guanylate cyclase 1 soluble subunit alpha 1"	Q02108	4	155666711-155732349	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 55.2"	"Cell line enhanced"	"Detected in some"		"HAP1: 6.0;Karpas-707: 8.5;MOLT-4: 15.6;RPTEC TERT1: 10.7;RT4: 12.5;SH-SY5Y: 7.9"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 24.9"	"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"NK-cell: 7.6;non-classical monocyte: 9.2;plasmacytoid DC: 11.6"	"Group enriched"	"Detected in many"	27	"dendritic cells: 11.6;monocytes: 9.2;NK-cells: 7.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010887, HPA056004, HPA058617"	Uncertain		Supported	Nucleoplasm			6100	Nucleoplasm		"CAB010887: AB_259901, HPA056004: , HPA058617: "	"unprognostic (4.81e-3)"	"unprognostic (2.60e-1)"	"unprognostic (3.03e-1)"	"unprognostic (2.15e-1)"	"unprognostic (1.99e-2)"	"unprognostic (7.77e-3)"	"unprognostic (1.07e-1)"	"prognostic favourable (2.38e-4)"	"unprognostic (1.85e-3)"	"unprognostic (6.46e-2)"	"unprognostic (3.42e-2)"	"unprognostic (7.16e-2)"	"prognostic unfavourable (7.59e-4)"	"unprognostic (1.60e-2)"	"prognostic unfavourable (3.59e-4)"	"unprognostic (2.27e-1)"	"unprognostic (6.55e-3)"	10.9	5.3	12.4	10.2	19.9	0.9	11.1	3.4	11.6	13.7	31.2	7.3	2.8	5.6	14.7	6.0	7.0	6.8	8.3	21.0	9.0	7.2	11.6	5.1	13.2	7.3	4.7	12.5	5.4	8.5	55.2	5.8	16.3	6.3	17.2	6.9	39.7	7.0	9.8	4.5	3.6	10.1	18.8	6.6	8.5	12.9	2.1	8.5	4.5	8.1	7.3	5.9	6.4	10.6	0.1	11.6	0.3	9.2	7.6	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	6.0	0.0	0.0	0.0	4.8	1.1	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.0	0.0	0.0	0.0	8.5	0.0	0.0	15.6	0.0	0.0	0.2	3.5	0.0	2.6	10.7	12.5	2.1	7.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.0	0.1	0.3	0.0	2.3	0.1	0.0	0.0	0.0	2.5	0.1	0.0	0.0	0.0	7.6	9.2	11.6	0.0	1.0	12.4	19.9	3.4	11.6	9.0	7.2	4.7	12.5	6.3	8.5
GUCY1A2	"GC-SA2, GUC1A2"	ENSG00000152402	"Guanylate cyclase 1 soluble subunit alpha 2"	P33402	11	106674012-107018524	"Enzymes, FDA approved drug targets, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 23.0;placenta: 23.6"	"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 12.2;BJ hTERT+ SV40 Large T+ RasG12V: 14.3;HBF TERT88: 7.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB009534	Uncertain									"CAB009534: AB_2279509"	"unprognostic (7.53e-2)"	"unprognostic (6.67e-2)"	"unprognostic (7.99e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.22e-2)"	"unprognostic (1.23e-2)"	"unprognostic (1.24e-1)"	"unprognostic (6.53e-3)"	"unprognostic (9.70e-3)"	"unprognostic (8.00e-2)"	"unprognostic (2.03e-1)"	"prognostic unfavourable (3.02e-5)"	"unprognostic (2.48e-4)"	"unprognostic (1.62e-1)"	"unprognostic (3.50e-2)"	"unprognostic (1.09e-2)"	5.5	3.3	4.6	1.3	10.9	0.6	3.9	4.3	10.7	19.2	1.5	1.2	1.1	0.9	23.0	5.0	1.3	8.4	2.6	3.8	4.6	4.0	3.2	2.8	11.8	1.6	3.7	5.3	3.9	6.2	1.8	1.5	23.6	5.5	3.2	1.3	1.4	1.4	10.1	4.1	1.4	1.2	18.0	2.4	7.9	1.0	2.8	5.4	0.0	2.4	3.0	1.0	2.2	5.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	4.3	0.0	0.2	2.6	2.3	0.3	12.2	1.6	14.3	0.0	0.0	0.0	0.0	0.9	0.0	0.2	0.0	7.6	0.0	1.2	0.0	0.1	0.0	0.2	0.0	1.7	0.7	0.0	1.9	0.2	0.9	0.0	0.0	0.0	0.2	0.1	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	2.7	0.5	3.7	0.0	0.8	0.8	0.2	4.7	3.9	3.2	0.8	1.3	0.0	0.0	0.0	0.1	0.0	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.6	10.9	4.3	9.9	4.6	4.0	3.7	5.3	5.5	5.4
GUCY1B1	"GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3"	ENSG00000061918	"Guanylate cyclase 1 soluble subunit beta 1"	Q02153	4	155758992-155807591	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 71.6"	"Cell line enhanced"	"Detected in many"		"HEL: 24.8;Karpas-707: 13.1;MOLT-4: 15.6;RPTEC TERT1: 25.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	8	"intermediate monocyte: 5.6;non-classical monocyte: 17.8"	"Lineage enriched"	"Detected in many"	12	"monocytes: 17.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010890, HPA020870"	Approved		Approved	Cytosol			5200	Cytosol		"CAB010890: AB_259911, HPA020870: AB_1850444"	"unprognostic (1.44e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.55e-2)"	"unprognostic (9.10e-3)"	"unprognostic (4.69e-2)"	"unprognostic (1.41e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.69e-3)"	"unprognostic (3.03e-3)"	"unprognostic (1.47e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.84e-1)"	"prognostic unfavourable (2.42e-4)"	"unprognostic (7.35e-3)"	"prognostic unfavourable (3.23e-4)"	"unprognostic (2.14e-1)"	"unprognostic (6.36e-3)"	8.8	5.4	18.7	9.8	42.0	1.8	5.5	12.2	36.8	8.1	14.9	5.7	0.4	4.2	11.3	4.7	5.9	9.5	9.2	12.2	16.1	25.0	9.2	5.4	9.4	6.6	14.5	23.2	3.7	7.4	71.6	3.8	28.0	20.6	9.8	6.2	5.8	3.2	8.7	3.8	2.2	5.9	16.3	6.7	7.2	8.9	2.1	5.5	2.6	4.6	2.4	5.1	8.0	6.8	0.2	1.4	1.1	17.8	0.9	0.0	4.8	0.0	0.2	3.5	0.0	1.2	6.6	0.0	1.1	1.9	0.1	0.0	0.0	0.0	0.0	1.7	0.6	0.0	7.3	0.1	0.4	0.0	2.6	24.8	0.0	0.0	0.7	0.0	0.0	2.9	0.2	0.0	0.1	0.0	0.0	13.1	1.7	1.1	15.6	0.0	0.2	1.8	1.8	0.5	0.4	25.2	2.3	0.4	4.4	0.0	0.1	0.0	0.0	0.0	0.0	4.1	0.9	7.1	5.2	0.1	0.0	0.0	9.0	0.0	0.0	1.1	0.4	0.3	0.0	5.6	0.0	0.1	0.0	0.0	1.4	0.2	0.0	0.0	0.4	0.9	17.8	1.2	0.0	4.8	18.7	42.0	12.2	36.8	16.1	25.0	14.5	23.2	20.6	5.5
GUCY2C	"GUC2C, STAR"	ENSG00000070019	"Guanylate cyclase 2C"	P25092	12	14612632-14696585	"Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters"	"cGMP biosynthesis"	"Lyase, Receptor"	"Disease mutation, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	19	"intestine: 85.1"	"Cell line enhanced"	"Detected in some"		"AN3-CA: 3.7;BEWO: 2.2;CACO-2: 3.1;CAPAN-2: 4.5;SiHa: 4.2"	"Group enriched"	"Detected in many"	5	"colorectal cancer: 23.9;stomach cancer: 9.1"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"memory B-cell: 4.3"	"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"HPA037655, HPA073759"	Uncertain		Uncertain	Vesicles				Vesicles		"HPA037655: AB_10672388, HPA073759: "	"unprognostic (1.08e-1)"	"unprognostic (2.12e-1)"	"unprognostic (3.58e-2)"	"unprognostic (2.11e-2)"	"unprognostic (1.60e-2)"	"unprognostic (5.67e-3)"	"prognostic unfavourable (1.37e-5)"	"unprognostic (9.14e-2)"	"unprognostic (1.49e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.58e-1)"	"unprognostic (5.40e-2)"	"unprognostic (2.35e-4)"	"unprognostic (8.02e-2)"	"unprognostic (1.64e-1)"	"unprognostic (1.33e-1)"	"unprognostic (1.98e-1)"	0.2	0.1	0.2	3.4	0.2	0.0	0.2	0.2	0.2	0.2	38.8	0.2	0.2	28.0	0.3	0.2	0.4	0.2	0.3	0.4	0.2	0.1	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.5	0.0	0.2	0.2	0.2	0.2	17.5	0.2	0.5	0.2	0.2	1.0	85.1	0.3	0.2	0.2	0.5	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.3	4.3	0.7	2.7	1.7	0.0	0.0	0.6	1.1	0.1	0.0	3.7	0.0	0.0	2.2	0.1	0.0	0.0	0.0	3.1	4.5	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.7	0.0	0.4	0.4	0.0	0.0	0.0	0.5	0.1	0.6	0.0	0.5	4.2	0.3	0.0	0.3	0.1	0.0	0.0	0.0	0.9	0.1	1.3	0.8	1.3	0.0	0.0	0.1	0.0	1.7	0.0	0.0	0.5	0.0	4.3	0.0	0.0	0.7	2.3	0.0	0.0	2.7	0.0	0.0	0.7	0.0	0.6	0.2	0.2	0.2	0.2	0.2	0.1	0.2	0.2	0.2	0.2
GUCY2D	"CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1"	ENSG00000132518	"Guanylate cyclase 2D, retinal"	Q02846	17	8002594-8020339	"Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters"	"cGMP biosynthesis, Sensory transduction, Vision"	Lyase	"Cone-rod dystrophy, Disease mutation, Leber congenital amaurosis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"blood: 10.6;retina: 33.3"	"Cell line enriched"	"Detected in single"	7	"HMC-1: 5.3"	"Low cancer specificity"	"Detected in single"			"Not detected"	"Not detected"			"Cell type enriched"	"Detected in single"	31	"plasmacytoid DC: 10.6"	"Lineage enriched"	"Detected in single"	53	"dendritic cells: 10.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"														"unprognostic (3.57e-4)"	"unprognostic (5.05e-1)"	"unprognostic (1.49e-1)"	"unprognostic (9.75e-5)"	"unprognostic (5.94e-2)"	"unprognostic (1.86e-1)"	"unprognostic (4.44e-2)"	"unprognostic (3.81e-2)"	"unprognostic (2.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (7.54e-2)"	"unprognostic (4.44e-1)"	"unprognostic (7.59e-5)"	"unprognostic (1.05e-1)"	"unprognostic (3.46e-1)"	"unprognostic (3.08e-1)"	"unprognostic (1.07e-1)"	0.1	0.0	0.1	0.3	0.1	0.5	0.1	0.1	0.2	0.1	0.1	0.2	0.1	0.0	0.1	0.2	0.5	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.2	1.3	0.3	0.1	0.2	0.1	0.0	0.1	0.1	0.1	0.4	0.0	33.3	0.4	0.1	0.1	0.4	0.1	0.1	0.1	0.6	0.1	5.0	0.1	0.2	0.1	0.1	0.9	0.1	0.2	0.0	10.6	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	5.3	0.6	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	10.6	0.0	0.0	0.1	0.1	0.1	0.2	0.1	0.2	0.3	0.1	0.1	0.1
GUCY2F	"CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2"	ENSG00000101890	"Guanylate cyclase 2F, retinal"	P51841	X	109372906-109482072	"Enzymes, Plasma proteins, Predicted membrane proteins"	"cGMP biosynthesis, Sensory transduction, Vision"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	10	"retina: 23.1"	"Group enriched"	"Detected in some"	5	"THP-1: 4.4;U-266/70: 1.6;U-937: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"																	"unprognostic (1.91e-1)"	"unprognostic (4.45e-2)"									"unprognostic (2.96e-1)"	"unprognostic (2.23e-1)"			0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.2	1.6	0.0	0.0	0.0	0.0	0.4	0.0	0.0	2.3	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.0	23.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.4	0.0	0.0	0.0	0.0	0.1	1.6	0.0	0.1	0.0	1.5	0.5	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0
HACD1	"CAP, PTPLA"	ENSG00000165996	"3-hydroxyacyl-CoA dehydratase 1"	B0YJ81	10	17589032-17617377	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	"Developmental protein, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 80.1"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	10	"T-reg: 27.6"	"Lineage enriched"	"Detected in many"	16	"T-cells: 27.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (2.73e-2)"	"unprognostic (3.26e-2)"	"unprognostic (3.54e-1)"	"unprognostic (2.62e-2)"	"unprognostic (4.10e-1)"	"unprognostic (5.67e-3)"	"unprognostic (4.21e-2)"	"unprognostic (3.04e-2)"	"unprognostic (2.38e-1)"	"unprognostic (1.70e-2)"	"unprognostic (2.61e-2)"	"unprognostic (3.43e-1)"	"unprognostic (2.46e-2)"	"unprognostic (2.93e-2)"	"unprognostic (3.40e-2)"	"unprognostic (1.10e-1)"	"unprognostic (6.49e-2)"	6.6	4.7	2.1	3.8	3.9	5.4	12.6	3.4	3.1	5.1	17.6	3.9	7.4	2.3	13.1	6.0	12.6	6.5	4.8	80.1	2.4	3.7	3.6	1.1	7.9	1.1	5.1	1.8	3.9	2.5	0.6	2.4	1.5	3.8	8.8	3.3	9.4	2.1	13.2	22.8	2.5	4.2	21.5	4.8	1.5	9.4	3.0	3.4	2.6	5.9	6.2	1.2	12.6	9.8	0.6	1.6	1.7	0.5	1.6	27.6	0.7	11.0	9.5	2.7	13.1	12.2	2.3	0.2	15.7	9.5	20.6	19.5	6.3	13.5	0.1	2.3	25.5	2.7	6.8	4.7	11.4	7.2	4.0	25.5	6.8	17.3	15.8	0.1	1.9	5.7	6.8	11.8	4.6	4.0	0.2	0.5	27.1	8.0	18.8	2.6	5.7	2.6	16.9	2.8	0.3	8.1	2.1	3.0	7.6	13.4	0.2	22.0	9.5	6.3	3.8	12.2	7.0	7.4	7.1	0.4	0.3	0.1	8.9	2.9	1.7	1.7	0.5	0.4	0.6	0.1	0.1	0.2	2.8	0.5	1.6	0.6	0.5	0.4	1.6	1.6	0.1	0.8	27.6	0.7	2.1	3.9	3.4	2.8	2.4	3.7	5.1	1.8	3.8	3.4
HACD2	PTPLB	ENSG00000206527	"3-hydroxyacyl-CoA dehydratase 2"	Q6Y1H2	3	123490820-123585185	"Enzymes, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SiHa: 64.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019282	Approved									"CAB019282: "	"unprognostic (3.04e-2)"	"unprognostic (2.51e-1)"	"unprognostic (6.11e-2)"	"unprognostic (2.65e-3)"	"unprognostic (5.36e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.32e-2)"	"unprognostic (1.95e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.22e-1)"	"prognostic unfavourable (9.59e-5)"	"unprognostic (6.90e-2)"	"unprognostic (7.03e-3)"	"unprognostic (1.48e-1)"	"unprognostic (3.85e-2)"	"unprognostic (1.94e-2)"	"unprognostic (2.59e-2)"	43.2	9.7	18.0	11.2	30.0	5.7	16.6	20.5	18.7	14.1	20.4	28.6	7.4	21.2	12.4	13.5	18.8	9.9	12.2	9.9	20.7	13.4	20.7	34.3	13.8	14.1	29.4	12.0	13.8	13.4	15.6	12.5	11.1	18.5	22.1	20.4	7.3	15.5	10.2	5.6	23.2	30.8	12.3	24.9	9.6	15.3	13.3	25.7	9.1	16.0	10.5	19.7	10.9	16.6	4.9	6.4	2.4	3.5	2.9	5.3	2.4	19.4	11.0	7.6	5.5	23.9	5.3	28.3	13.9	5.8	14.5	10.5	22.5	17.2	11.2	10.1	13.3	42.5	13.6	17.5	15.3	7.1	4.5	7.8	10.4	17.4	7.8	10.3	7.8	7.3	45.1	7.0	19.7	7.5	1.5	11.2	8.7	15.1	4.9	3.1	9.8	9.8	7.5	8.3	11.9	17.5	12.5	13.4	4.2	64.8	13.8	8.8	14.4	5.4	5.8	15.2	11.4	15.2	13.5	6.7	8.5	9.2	6.8	7.3	8.1	1.5	3.5	2.4	3.6	2.8	5.3	3.4	4.8	4.6	6.4	4.9	4.4	4.3	1.1	2.9	2.2	3.7	5.3	2.4	18.0	30.0	20.5	18.7	20.7	13.4	29.4	12.0	18.5	25.7
HACD3	"B-ind1, HSPC121, PTPLAD1"	ENSG00000074696	"3-hydroxyacyl-CoA dehydratase 3"	Q9P035	15	65530418-65578352	"Enzymes, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA014837, HPA060347"	Enhanced		Enhanced	"Endoplasmic reticulum"			27000	"Endoplasmic reticulum"		"HPA014837: AB_1855914, HPA060347: "	"unprognostic (1.51e-2)"	"unprognostic (2.89e-1)"	"unprognostic (2.29e-1)"	"unprognostic (2.18e-1)"	"unprognostic (3.52e-1)"	"unprognostic (1.92e-2)"	"unprognostic (1.67e-1)"	"unprognostic (2.28e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.57e-1)"	"prognostic favourable (3.09e-5)"	"unprognostic (3.44e-2)"	"unprognostic (5.33e-2)"	"unprognostic (1.10e-2)"	"unprognostic (2.04e-2)"	9.6	37.4	31.0	7.4	36.0	6.2	33.3	28.6	37.6	18.5	12.5	24.2	10.1	12.2	13.1	19.4	8.4	14.3	14.7	5.9	29.2	44.8	35.0	50.0	12.7	7.2	36.5	26.0	21.7	12.6	22.5	33.9	15.9	45.9	18.5	15.1	17.9	11.6	15.8	3.3	11.7	12.0	12.2	41.5	8.5	29.0	13.9	19.7	8.9	30.7	5.6	8.3	18.8	10.4	13.0	9.0	2.7	6.1	11.7	19.9	11.2	19.6	44.0	49.0	24.4	30.9	18.7	23.2	21.8	18.9	24.8	28.1	33.7	29.5	24.8	19.1	23.6	54.4	78.9	18.2	22.3	13.7	44.0	19.6	22.1	36.8	15.7	24.3	15.1	19.1	13.6	17.0	12.3	24.1	25.7	9.4	40.0	23.4	18.0	19.0	41.7	15.0	20.4	41.5	27.9	35.4	34.2	29.6	26.1	23.5	26.5	24.6	26.9	12.9	19.1	31.6	27.8	15.5	30.2	18.4	54.5	34.9	21.0	23.8	18.9	2.7	3.9	1.2	17.6	5.8	19.9	13.0	16.1	16.6	6.8	13.0	18.9	18.5	0.4	11.7	6.1	9.0	12.4	11.2	31.0	36.0	28.6	34.1	29.2	44.8	36.5	26.0	45.9	19.7
HACD4	"Em:AL662879.1, PTPLAD2"	ENSG00000188921	"3-hydroxyacyl-CoA dehydratase 4"	Q5VWC8	9	20999515-21031636	"Enzymes, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 15.5;HDLM-2: 9.4;TIME: 7.7;U-937: 11.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA058666	Uncertain									"HPA058666: "	"unprognostic (1.71e-1)"	"unprognostic (2.58e-2)"	"unprognostic (5.47e-2)"	"unprognostic (1.70e-2)"	"unprognostic (7.66e-2)"	"unprognostic (1.87e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.28e-2)"	"unprognostic (1.11e-4)"	"prognostic favourable (3.14e-4)"	"unprognostic (8.72e-2)"	"unprognostic (1.63e-1)"	"prognostic unfavourable (6.77e-4)"	"unprognostic (3.89e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.00e-3)"	4.3	7.9	4.9	9.2	7.1	16.3	10.3	3.3	3.1	8.9	10.1	2.6	1.2	3.2	6.9	5.6	10.7	6.5	7.6	7.5	4.1	3.2	3.3	1.8	24.1	18.2	5.2	1.8	6.5	1.9	4.0	2.3	9.9	3.7	5.9	5.0	6.3	3.6	3.8	1.5	4.7	7.5	11.5	9.6	10.1	5.4	1.8	5.5	19.9	4.1	6.2	7.9	5.1	5.6	1.2	8.4	13.6	8.8	3.0	3.0	3.9	3.7	1.1	0.4	0.1	0.0	0.1	0.1	3.4	15.5	2.8	3.2	0.0	0.0	3.3	1.9	6.5	1.0	0.2	1.4	3.5	9.4	0.1	0.0	1.1	0.0	2.1	2.7	3.0	6.2	6.1	2.5	0.0	0.9	0.0	1.9	0.5	0.1	0.0	3.8	0.8	0.0	0.0	0.0	0.1	0.1	0.4	0.6	0.0	0.8	0.3	0.0	2.8	5.2	7.7	0.0	0.0	0.2	0.1	0.1	0.1	0.1	0.0	11.9	0.1	13.6	7.1	11.4	2.2	8.8	2.0	1.2	2.4	2.5	8.4	1.2	1.7	2.4	10.2	3.0	8.5	0.9	3.0	3.9	4.9	7.1	3.3	3.1	4.1	3.2	5.2	1.8	3.7	5.5
HADHA	"GBP, LCEH, LCHAD, MTPA"	ENSG00000084754	"Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha"	P40939	2	26190635-26244726	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Lyase, Multifunctional enzyme, Oxidoreductase, Transferase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015536, HPA056070"	Approved		Enhanced	Mitochondria			2700000	Mitochondria		"HPA015536: AB_1850473, HPA056070: "	"unprognostic (2.02e-1)"	"unprognostic (1.38e-2)"	"unprognostic (2.55e-1)"	"unprognostic (3.43e-1)"	"unprognostic (2.67e-2)"	"unprognostic (3.23e-2)"	"unprognostic (1.25e-2)"	"unprognostic (2.02e-1)"	"unprognostic (5.16e-2)"	"unprognostic (3.45e-1)"	"unprognostic (3.81e-1)"	"unprognostic (1.16e-1)"	"prognostic favourable (3.68e-5)"	"unprognostic (7.97e-2)"	"unprognostic (1.71e-1)"	"unprognostic (2.87e-3)"	"unprognostic (2.64e-2)"	41.6	35.3	18.1	13.1	19.5	17.0	23.9	17.4	16.9	20.2	44.9	26.5	15.7	48.1	21.1	15.3	30.8	20.5	15.1	80.0	15.6	15.5	41.3	71.7	17.7	19.3	21.6	13.1	27.3	37.5	29.8	23.5	21.3	24.8	21.9	32.2	23.6	21.1	16.6	117.5	23.3	66.4	25.1	27.8	24.0	24.1	18.7	19.0	25.2	25.1	41.3	24.6	26.9	18.8	15.3	28.9	12.4	32.2	13.5	17.6	26.0	23.3	20.8	13.7	22.4	54.5	34.1	11.7	18.3	19.8	18.9	16.4	26.3	22.7	15.4	12.0	32.1	14.9	24.0	35.5	17.1	34.5	29.4	23.1	22.1	43.8	18.8	29.1	17.0	34.8	23.3	26.8	26.9	31.6	31.4	31.3	24.3	28.6	12.7	32.6	11.7	40.2	11.7	29.6	33.1	21.6	28.2	9.7	19.3	21.5	22.4	24.8	11.9	28.2	28.9	11.0	16.3	16.4	13.4	10.3	20.3	27.4	17.1	34.5	13.2	8.1	27.7	12.4	12.3	32.2	14.8	15.3	14.2	15.0	28.9	11.2	16.7	15.3	7.4	13.5	28.0	11.0	17.6	26.0	18.1	19.5	17.4	16.9	15.6	15.5	21.6	13.1	24.8	19.0
HAL	HIS	ENSG00000084110	"Histidine ammonia-lyase"	P42357	12	95972662-95996365	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Histidine metabolism"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	7	"blood: 29.5;liver: 96.8;skin 1: 26.9"	"Cell line enhanced"	"Detected in some"		"BEWO: 3.1;NB-4: 3.9;THP-1: 15.1"	"Cancer enriched"	"Detected in some"	11	"liver cancer: 23.7"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in many"		"basophil: 20.1;neutrophil: 29.5"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 29.5"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA038547, HPA038548"	Enhanced		Approved	Cytosol			67000	Cytosol		"HPA038547: AB_10669541, HPA038548: AB_10673175"	"unprognostic (3.39e-1)"	"unprognostic (4.46e-2)"	"unprognostic (1.53e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.32e-2)"	"unprognostic (1.20e-2)"	"unprognostic (5.05e-2)"	"unprognostic (2.80e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.33e-2)"	"unprognostic (9.41e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.31e-3)"	"unprognostic (1.89e-2)"	"unprognostic (3.74e-1)"	"unprognostic (4.03e-2)"	"unprognostic (2.87e-2)"	0.5	0.0	0.1	1.1	0.3	4.4	0.9	0.1	0.3	0.3	0.2	0.1	0.1	0.1	1.1	0.3	0.5	0.2	0.3	0.2	0.1	0.0	0.2	96.8	1.7	2.3	0.5	0.1	0.3	0.5	0.0	7.4	0.4	0.2	0.2	0.0	0.1	0.2	0.1	0.2	26.9	0.2	0.2	0.3	2.7	0.1	0.2	0.2	0.1	0.2	0.9	1.3	0.2	0.5	0.0	1.4	29.5	6.3	0.3	0.1	1.6	0.5	0.0	0.2	0.1	0.0	0.0	3.1	0.0	0.2	0.1	0.2	0.0	0.1	0.9	0.0	0.0	0.2	0.3	0.1	0.1	0.2	0.5	0.4	0.2	0.0	0.0	0.6	0.6	0.0	0.9	0.4	0.4	0.3	0.0	0.2	0.1	0.0	0.2	3.9	1.3	0.6	0.2	0.1	0.1	0.1	0.8	0.2	0.4	0.4	0.1	0.0	0.0	15.1	0.2	0.1	0.2	0.2	0.2	0.6	0.7	0.2	0.0	2.4	0.0	20.1	6.3	0.9	0.0	2.2	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	29.5	0.3	5.1	0.1	0.1	1.6	0.1	0.3	0.1	0.3	0.1	0.0	0.5	0.1	0.2	0.2
HCCS	"CCHL, MLS"	ENSG00000004961	"Holocytochrome c synthase"	P53701	X	11111301-11123078	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002946	Approved		Enhanced	Mitochondria	"Intracellular and membrane"			Mitochondria		"HPA002946: AB_1079041"	"prognostic unfavourable (8.69e-5)"	"unprognostic (6.89e-3)"	"unprognostic (8.46e-3)"	"unprognostic (4.92e-2)"	"unprognostic (1.34e-1)"	"unprognostic (5.44e-2)"	"prognostic unfavourable (1.35e-5)"	"unprognostic (9.18e-2)"	"unprognostic (2.73e-1)"	"unprognostic (2.52e-2)"	"unprognostic (2.10e-2)"	"unprognostic (1.60e-1)"	"prognostic favourable (6.17e-8)"	"unprognostic (2.66e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.93e-2)"	10.6	14.2	8.8	9.0	12.7	11.8	9.6	11.0	17.7	6.7	15.5	7.4	8.0	17.2	8.5	5.5	15.8	6.9	9.8	36.9	8.4	8.3	15.9	19.0	9.5	10.1	8.2	11.1	10.0	11.4	11.5	10.0	12.8	10.6	7.8	15.2	9.3	12.8	8.0	41.6	13.8	14.4	10.4	6.3	12.3	12.2	10.5	6.0	10.3	10.8	16.4	11.8	11.4	17.3	18.1	28.4	13.3	29.7	8.4	11.1	8.7	23.2	26.8	12.5	12.0	11.8	11.4	13.3	23.5	17.9	29.7	25.5	31.1	17.0	14.5	12.1	18.8	21.6	25.9	22.4	29.0	13.5	20.3	14.5	34.4	15.5	20.9	15.8	17.7	11.1	17.5	28.2	19.3	21.0	26.8	16.8	19.9	31.5	11.4	12.8	22.7	29.0	11.2	25.2	28.4	20.0	18.3	9.1	10.7	23.4	25.5	15.0	19.7	11.4	20.6	19.3	10.4	49.2	20.0	12.4	12.6	19.2	15.5	12.7	18.4	10.1	22.5	13.3	9.9	29.7	9.5	18.1	9.7	8.9	28.4	15.5	8.5	11.1	6.2	8.4	24.8	25.9	10.4	8.7	8.8	12.7	11.0	17.7	8.4	8.3	8.2	11.1	10.6	6.0
HDC		ENSG00000140287	"Histidine decarboxylase"	P19113	15	50241947-50266026	"Enzymes, Predicted intracellular proteins"	"Catecholamine biosynthesis"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"		"Group enriched"	"Detected in many"	8	"blood: 83.5;brain: 36.0;epididymis: 36.9"	"Group enriched"	"Detected in some"	4	"HEL: 59.8;HMC-1: 143.8"	"Low cancer specificity"	"Detected in some"			"Region enriched"	"Detected in single"	52	"hypothalamus: 36.0"	"Cell type enriched"	"Detected in single"	835	"basophil: 83.5"	"Lineage enriched"	"Detected in single"	835	"granulocytes: 83.5"	"Region enriched"	"Detected in many"	5	"hypothalamus: 51.5"	"Low region specificity"	"Detected in all"			HPA038891	Enhanced		Approved	"Nuclear bodies"				"Nuclear bodies"		"HPA038891: AB_10673231"	"unprognostic (4.97e-2)"	"unprognostic (7.42e-2)"	"unprognostic (1.43e-4)"	"unprognostic (1.08e-1)"	"unprognostic (6.16e-2)"	"unprognostic (3.93e-7)"	"unprognostic (4.18e-5)"	"unprognostic (8.79e-3)"	"unprognostic (1.48e-1)"	"unprognostic (8.46e-2)"	"unprognostic (4.60e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-1)"	"unprognostic (7.20e-2)"	"unprognostic (9.78e-2)"	"unprognostic (2.15e-1)"	"unprognostic (1.50e-1)"	1.7	0.2	0.2	5.1	0.4	2.4	1.1	0.2	0.3	2.7	1.9	0.2	1.2	2.1	3.1	36.9	2.7	0.6	6.6	2.1	0.2	36.0	0.6	0.8	4.9	2.3	0.6	0.1	0.4	0.5	0.3	0.7	0.2	0.3	2.2	1.9	3.0	0.9	1.3	1.8	1.8	2.4	5.4	0.2	0.4	6.9	2.4	0.2	0.4	0.3	0.4	1.7	1.8	2.7	0.0	0.0	83.5	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	59.8	0.0	0.0	0.0	0.1	143.8	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	22.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	83.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.4	0.2	0.3	0.2	36.0	0.6	0.1	0.3	0.2
HMGCL	HL	ENSG00000117305	"3-hydroxymethyl-3-methylglutaryl-CoA lyase"	P35914	1	23801885-23838620	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 81.4"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA004727	Enhanced				"Intracellular and membrane"		120000			"HPA004727: AB_1079074"	"unprognostic (8.24e-2)"	"unprognostic (3.21e-2)"	"prognostic favourable (7.67e-4)"	"unprognostic (1.23e-3)"	"unprognostic (5.47e-3)"	"unprognostic (1.26e-1)"	"unprognostic (2.04e-1)"	"unprognostic (3.85e-2)"	"unprognostic (1.08e-1)"	"unprognostic (2.24e-1)"	"unprognostic (3.05e-1)"	"unprognostic (8.24e-2)"	"prognostic favourable (5.07e-8)"	"unprognostic (1.72e-1)"	"unprognostic (2.46e-2)"	"unprognostic (8.60e-2)"	"unprognostic (3.39e-3)"	7.4	18.5	6.4	8.2	6.6	1.6	14.3	4.3	7.7	7.6	13.9	9.0	12.0	12.0	6.2	13.2	9.1	9.7	12.8	11.2	5.9	6.0	30.3	81.4	8.8	11.1	7.5	7.1	6.1	15.2	13.1	7.8	8.5	7.9	8.7	14.2	10.0	8.9	11.5	15.2	7.0	15.4	11.7	9.3	8.6	10.8	7.2	6.1	8.3	14.5	8.1	8.3	8.8	6.7	24.1	27.7	40.8	33.8	24.5	21.2	26.8	10.7	6.2	7.0	5.2	28.5	21.8	2.7	8.5	15.0	9.3	11.3	3.9	20.9	5.6	17.6	13.3	8.7	8.3	13.8	10.1	11.5	6.3	7.5	5.5	8.8	36.9	2.9	5.0	25.2	20.6	12.2	23.4	12.6	7.6	8.0	16.9	11.0	4.5	5.8	1.8	8.6	6.5	5.7	10.4	21.8	5.6	5.9	5.2	11.1	4.2	18.8	13.3	7.3	9.3	7.7	4.7	14.0	3.6	11.4	5.6	5.0	19.1	10.9	8.9	40.8	32.4	30.1	18.4	30.4	20.1	21.9	20.0	21.2	27.7	24.1	20.3	19.4	12.2	24.5	33.8	20.6	20.8	26.8	6.4	6.6	4.3	7.7	5.9	6.0	7.5	7.1	7.9	6.1
HMGCLL1	"bA418P12.1, DKFZP434G1411"	ENSG00000146151	"3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1"	Q8TB92	6	55434369-55579214	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 18.4;pituitary gland: 14.8"	"Cell line enriched"	"Detected in some"	9	"SCLC-21H: 11.6"	"Low cancer specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (2.74e-3)"		"unprognostic (1.54e-2)"	"unprognostic (4.08e-3)"	"unprognostic (6.11e-2)"	"unprognostic (1.41e-1)"	"unprognostic (9.54e-3)"	"unprognostic (8.97e-3)"		"unprognostic (2.12e-2)"	"unprognostic (9.27e-3)"	"unprognostic (4.11e-2)"	"unprognostic (1.18e-4)"	"unprognostic (3.13e-3)"	"unprognostic (7.57e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.52e-1)"	2.2	7.7	7.7	0.9	14.5	0.5	3.4	10.1	18.4	2.2	1.7	3.1	0.3	0.8	0.8	0.6	2.5	1.5	1.8	4.1	8.7	12.6	2.2	1.8	5.7	1.1	9.1	10.0	1.3	3.6	0.8	14.8	12.5	14.6	7.0	2.2	4.8	2.1	2.9	2.4	0.6	2.4	1.6	10.1	0.6	2.9	5.5	3.3	0.0	0.9	0.0	1.0	2.7	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	11.6	0.3	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.6	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.7	14.5	10.1	12.6	8.7	12.6	9.1	10.0	14.6	3.3
HOGA1	"C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2"	ENSG00000241935	"4-hydroxy-2-oxoglutarate aldolase 1"	Q86XE5	10	97584323-97612802	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 39.8;liver: 31.0"	"Group enriched"	"Detected in some"	4	"AN3-CA: 6.0;EFO-21: 7.2;Hep G2: 18.5;RPTEC TERT1: 22.8"	"Group enriched"	"Detected in many"	5	"liver cancer: 4.5;renal cancer: 9.7"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA039466	Approved						15000			"HPA039466: "	"unprognostic (6.44e-2)"	"unprognostic (3.64e-2)"	"unprognostic (7.50e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.29e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.59e-3)"	"unprognostic (4.72e-1)"	"unprognostic (2.37e-1)"	"unprognostic (1.28e-1)"	"unprognostic (6.80e-2)"	"prognostic favourable (9.08e-4)"	"unprognostic (2.20e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.94e-3)"	"unprognostic (7.20e-4)"	3.3	5.4	3.3	0.6	3.8	0.8	2.1	7.0	4.3	0.8	0.6	8.2	1.5	0.7	0.9	4.0	1.3	2.0	3.8	10.1	4.2	2.8	39.8	31.0	0.9	0.7	9.3	5.2	0.6	12.0	2.0	2.4	0.6	7.2	1.3	0.6	3.6	1.8	2.2	2.0	1.2	0.6	0.8	8.2	0.7	0.6	0.7	6.9	0.0	1.8	4.1	0.6	0.8	0.6	2.1	1.7	4.4	1.2	1.2	1.3	0.5	0.3	2.7	0.1	6.0	1.2	0.3	0.1	0.1	0.2	0.1	0.0	2.2	0.3	0.2	7.2	0.1	2.0	0.1	0.2	0.1	0.2	3.1	0.1	1.0	18.5	0.8	0.2	0.2	0.3	0.6	0.2	0.1	0.3	0.1	0.4	0.4	1.2	0.1	0.2	0.2	0.0	0.2	0.5	0.4	22.8	0.4	0.5	0.9	0.1	1.1	0.7	2.1	0.1	0.3	0.7	0.2	0.4	0.2	0.4	0.6	0.1	1.5	0.3	0.1	2.4	1.1	1.2	1.2	0.9	1.0	1.1	1.3	0.9	0.5	2.1	1.1	1.2	4.4	1.2	1.2	1.7	0.9	0.5	3.3	3.8	7.0	3.9	4.2	2.8	9.3	5.2	7.2	6.9
HSD17B4	"DBP, MFE-2, SDR8C1"	ENSG00000133835	"Hydroxysteroid 17-beta dehydrogenase 4"	P51659	5	119452443-119637199	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	"Isomerase, Lyase, Oxidoreductase"	"Deafness, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021302, HPA021311, HPA021479"	Enhanced		Enhanced	Peroxisomes			6900000	Peroxisomes		"HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352"	"unprognostic (1.03e-1)"	"unprognostic (1.05e-1)"	"prognostic favourable (1.33e-4)"	"unprognostic (3.21e-2)"	"unprognostic (1.24e-2)"	"unprognostic (3.12e-2)"	"unprognostic (2.83e-3)"	"unprognostic (5.47e-2)"	"unprognostic (1.54e-1)"	"unprognostic (2.03e-2)"	"unprognostic (1.02e-1)"	"unprognostic (3.85e-1)"	"prognostic favourable (6.31e-6)"	"unprognostic (1.60e-1)"	"unprognostic (8.26e-2)"	"unprognostic (1.80e-1)"	"unprognostic (6.65e-3)"	25.1	42.4	22.1	15.5	21.3	6.4	46.0	12.3	23.6	27.8	30.1	24.1	83.8	28.6	16.2	20.7	24.6	15.1	20.6	27.3	23.8	21.2	31.3	116.3	30.5	16.7	27.0	21.7	15.1	29.9	33.2	20.5	19.0	23.9	20.9	25.2	10.7	20.0	86.2	20.7	19.2	30.5	15.6	33.6	16.9	20.7	8.1	25.5	10.8	48.9	17.3	14.5	24.1	25.3	6.1	11.1	31.4	13.6	3.2	4.2	5.3	17.7	15.3	28.8	38.1	71.9	33.8	15.2	17.3	23.3	16.4	29.9	12.6	29.5	23.7	35.6	18.7	17.8	21.1	37.6	25.6	25.9	19.5	31.2	16.6	24.1	18.3	9.8	48.9	29.4	15.8	17.6	16.5	28.0	10.6	13.8	17.8	15.4	15.0	6.4	21.3	10.8	19.2	28.8	25.6	26.2	49.0	21.7	18.7	40.6	6.4	18.9	23.6	16.6	19.9	16.1	11.0	17.7	14.1	7.0	14.7	8.7	18.3	26.3	15.8	31.4	13.6	24.7	3.4	8.0	4.2	6.1	3.2	2.9	11.1	5.8	3.1	2.9	2.4	3.2	7.8	6.9	2.0	5.3	22.1	21.3	12.3	23.6	23.8	21.2	27.0	21.7	23.9	25.5
KYAT1	"CCBL1, GTK, KATI"	ENSG00000171097	"Kynurenine aminotransferase 1"	Q16773	9	128832942-128882494	"Enzymes, Predicted intracellular proteins"		"Aminotransferase, Lyase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021176, HPA021177, HPA027736"	Approved		Supported	Cytosol			21000	Cytosol		"HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818"	"unprognostic (6.51e-2)"	"unprognostic (8.67e-3)"	"unprognostic (1.05e-2)"	"unprognostic (5.98e-3)"	"unprognostic (2.15e-2)"	"unprognostic (5.44e-2)"	"unprognostic (2.91e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.47e-1)"	"unprognostic (8.60e-3)"	"unprognostic (1.43e-1)"	"unprognostic (3.65e-2)"	"unprognostic (3.10e-2)"	"unprognostic (5.79e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.98e-1)"	4.4	5.2	12.2	5.1	18.9	3.9	7.0	17.8	17.6	4.7	3.8	14.2	5.5	4.1	5.5	5.4	4.6	8.5	4.8	13.5	12.1	9.3	8.1	12.0	4.1	7.3	18.4	12.1	7.1	5.0	8.9	8.1	4.5	12.2	8.9	2.7	5.8	7.0	8.4	17.0	12.2	4.8	5.8	10.2	5.8	4.0	6.9	17.2	3.7	7.5	2.8	7.4	8.1	8.1	12.1	7.6	3.5	5.1	4.6	9.6	4.9	4.0	9.3	8.5	8.4	7.7	9.7	4.4	5.6	6.4	5.5	8.3	5.1	7.6	7.8	2.8	4.2	13.2	12.6	10.9	7.1	8.7	8.8	5.1	22.5	9.2	6.9	4.9	2.2	4.2	6.9	7.2	6.9	9.7	7.8	6.9	7.2	2.6	11.3	3.3	14.9	7.2	13.5	7.3	14.5	7.6	1.7	9.0	7.7	8.9	2.2	5.1	5.4	1.9	6.4	4.2	7.2	6.2	4.9	12.7	10.7	9.6	8.0	7.6	3.4	0.1	3.1	3.3	7.8	2.2	6.2	12.1	8.1	8.1	7.6	5.8	8.6	9.6	3.5	4.6	5.1	4.8	8.7	4.9	12.2	18.9	17.8	17.6	12.1	9.3	18.4	12.1	12.2	17.2
KYAT3	"CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3"	ENSG00000137944	"Kynurenine aminotransferase 3"	Q6YP21	1	88935773-88992953	"Enzymes, Predicted intracellular proteins"		"Aminotransferase, Lyase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA026538, HPA027168"	Enhanced		Approved	Nucleoli,Cytosol				"Nucleoli, Cytosol"		"HPA026538: AB_1852076, HPA027168: AB_1852078"	"prognostic favourable (3.19e-5)"	"unprognostic (3.36e-3)"	"unprognostic (1.88e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.01e-2)"	"prognostic favourable (1.86e-4)"	"unprognostic (2.61e-1)"	"unprognostic (3.61e-3)"	"unprognostic (2.11e-1)"	"prognostic favourable (2.80e-4)"	"unprognostic (1.04e-1)"	"unprognostic (3.17e-1)"	"prognostic favourable (5.02e-6)"	"unprognostic (1.17e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.51e-1)"	"unprognostic (2.78e-1)"	22.2	26.8	16.6	13.2	19.3	10.6	27.5	14.9	23.5	23.7	17.5	20.0	13.0	19.4	24.1	21.2	27.2	18.9	17.8	13.2	18.6	14.2	27.3	23.8	17.1	17.6	16.9	22.2	27.4	28.6	27.0	19.5	21.9	23.4	19.0	19.6	19.5	21.0	20.7	10.4	22.0	17.2	22.1	14.8	20.7	23.5	15.6	17.2	15.5	24.5	13.4	20.2	25.2	17.7	9.6	17.0	9.2	12.7	11.5	16.7	8.2	20.4	4.3	20.9	7.0	7.5	21.0	18.2	12.6	23.7	16.1	21.0	6.2	7.2	13.5	9.6	9.3	5.8	5.9	9.7	24.7	7.9	8.4	12.1	4.1	10.3	24.6	16.9	3.3	17.7	9.8	11.0	20.0	15.6	15.5	7.1	15.1	6.7	18.0	8.2	12.5	3.8	18.4	14.7	7.2	33.9	20.9	15.3	18.6	16.7	22.3	10.9	12.3	4.1	10.4	6.8	4.5	21.6	9.1	9.6	4.8	9.0	3.3	7.5	5.7	5.6	12.7	7.1	9.1	7.9	12.6	9.6	11.8	10.5	17.0	9.3	12.4	10.4	9.2	11.5	10.2	6.3	16.7	8.2	16.6	19.3	14.9	23.5	18.6	14.2	16.9	22.2	23.4	17.2
L3HYPDH	"C14orf149, FLJ25436"	ENSG00000126790	"Trans-L-3-hydroxyproline dehydratase"	Q96EM0	14	59460363-59484430	"Enzymes, Predicted intracellular proteins"		Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056694	Approved		Uncertain	Vesicles			16000	Vesicles		"HPA056694: "	"unprognostic (3.39e-2)"	"unprognostic (5.55e-3)"	"unprognostic (3.81e-2)"	"unprognostic (5.86e-2)"	"unprognostic (1.10e-1)"	"unprognostic (5.06e-2)"	"unprognostic (8.34e-2)"	"unprognostic (1.16e-1)"	"unprognostic (7.24e-2)"	"unprognostic (9.50e-2)"	"unprognostic (1.26e-3)"	"unprognostic (6.60e-2)"	"prognostic unfavourable (1.72e-9)"	"unprognostic (1.16e-1)"	"unprognostic (2.22e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.14e-1)"	17.9	15.4	13.5	13.5	17.1	4.9	22.8	10.4	16.5	12.6	9.9	18.5	10.9	12.3	17.6	10.3	9.8	16.3	13.2	15.9	13.6	7.2	20.2	17.4	11.5	18.5	22.7	9.6	20.1	12.8	23.1	22.5	11.9	18.2	15.5	12.0	12.9	13.6	15.5	8.7	11.0	13.7	14.0	18.4	14.3	11.0	18.9	17.4	6.6	17.9	9.9	15.0	12.7	18.7	2.3	7.9	0.8	7.0	7.0	5.1	2.5	6.1	16.6	3.6	8.5	7.8	20.7	5.1	16.6	13.2	9.6	9.4	3.3	11.1	2.1	7.0	9.2	16.7	5.8	8.9	9.5	3.5	7.5	5.7	14.5	12.0	8.9	5.0	4.1	14.9	6.1	9.6	14.9	11.7	7.4	9.8	9.9	7.3	1.9	8.3	5.8	15.0	2.8	5.9	8.4	15.4	3.5	3.7	5.3	15.6	6.5	5.9	6.8	3.3	16.3	11.3	13.7	8.7	19.4	2.5	1.1	2.0	19.4	4.3	21.9	0.0	5.0	0.8	5.1	7.0	3.4	2.3	2.5	3.0	7.9	2.2	3.9	1.4	0.0	7.0	3.2	4.3	1.1	2.5	13.5	17.1	10.4	16.5	13.6	7.2	22.7	9.6	18.2	17.4
LTC4S	MGC33147	ENSG00000213316	"Leukotriene C4 synthase"	Q16873	5	179793980-179796647	"Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"	"Leukotriene biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"blood: 31.3"	"Cell line enriched"	"Detected in some"	10	"HMC-1: 50.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 8.5;eosinophil: 31.3"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 31.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA044688			Approved	"Nucleoplasm,Endoplasmic reticulum,Cytosol"				Nucleoplasm	"Endoplasmic reticulum, Cytosol"	"HPA044688: "	"unprognostic (8.94e-2)"	"unprognostic (2.40e-2)"			"unprognostic (9.35e-3)"		"unprognostic (3.57e-2)"	"unprognostic (1.24e-2)"		"unprognostic (9.40e-2)"	"unprognostic (4.53e-5)"	"unprognostic (2.27e-2)"	"unprognostic (1.06e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.65e-1)"	"unprognostic (1.98e-2)"	"unprognostic (4.62e-1)"	9.0	6.7	3.5	2.8	3.5	8.6	4.6	1.7	5.0	6.9	5.0	9.4	5.4	3.6	8.7	10.4	4.2	13.0	15.7	11.3	3.9	3.1	6.2	2.3	28.3	8.0	6.8	4.2	5.8	2.4	2.0	3.2	2.9	4.3	5.6	1.9	3.3	7.4	11.6	2.7	3.5	5.7	4.5	6.3	6.7	5.0	3.3	3.9	0.8	5.3	5.6	3.2	3.6	3.9	0.1	4.5	31.3	0.3	2.2	1.7	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.4	5.1	0.0	0.2	0.2	0.3	50.9	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.5	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.4	0.0	8.5	0.2	31.3	0.5	0.3	1.7	0.1	1.2	0.8	4.5	0.1	0.2	0.5	0.1	2.2	0.0	0.2	0.1	0.3	3.5	3.5	1.7	5.0	3.9	3.1	6.8	4.2	4.3	3.9
MLYCD	"hMCD, MCD"	ENSG00000103150	"Malonyl-CoA decarboxylase"	O95822	16	83899126-83927026	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 39.1"	"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"											HPA031625	Enhanced									"HPA031625: AB_10602028"	"unprognostic (6.23e-2)"	"unprognostic (1.94e-1)"	"unprognostic (9.07e-2)"	"unprognostic (2.76e-2)"	"unprognostic (1.89e-1)"	"unprognostic (1.95e-1)"	"unprognostic (1.26e-1)"	"unprognostic (2.36e-2)"	"unprognostic (1.28e-1)"	"unprognostic (6.23e-2)"	"unprognostic (1.84e-4)"	"unprognostic (2.33e-1)"	"prognostic favourable (2.61e-7)"	"unprognostic (2.39e-1)"	"unprognostic (3.19e-1)"	"unprognostic (9.56e-2)"	"unprognostic (1.51e-3)"	6.6	10.1	3.3	3.7	4.2	2.3	4.6	2.4	5.4	4.1	6.9	6.3	6.2	4.6	4.4	4.4	5.1	4.9	7.0	39.1	3.7	3.3	6.7	17.4	4.1	3.6	6.9	3.1	6.2	21.5	6.9	5.1	3.1	4.6	5.6	4.4	8.0	6.4	4.1	31.0	4.0	5.1	5.8	3.3	3.8	6.7	7.1	5.7	3.3	5.6	5.7	4.6	6.4	5.4	0.7	0.7	2.3	0.8	0.1	0.9	0.2	0.5	2.3	1.6	2.6	4.9	2.4	3.6	1.1	1.7	1.1	0.5	2.2	1.6	0.4	2.8	2.1	2.4	2.7	0.8	1.0	1.8	2.1	1.6	0.9	1.3	2.8	1.4	3.2	3.0	2.7	0.7	1.1	1.2	2.1	0.8	1.3	4.3	1.5	4.4	2.0	1.0	3.4	1.4	2.1	2.9	2.7	2.4	2.2	4.4	0.6	2.0	4.2	1.8	1.6	1.7	0.4	1.3	0.5	2.7	2.6	3.1	1.7	2.1	1.9	0.8	0.7	2.3	0.5	0.5	0.3	0.7	0.8	0.7	0.7	0.3	0.8	0.9	0.3	0.1	0.8	0.3	0.0	0.2	3.3	4.2	2.4	5.4	3.7	3.3	6.9	3.1	4.6	5.7
MOCS1	MOCOD	ENSG00000124615	"Molybdenum cofactor synthesis 1"	Q9NZB8	6	39899578-39934551	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Molybdenum cofactor biosynthesis"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"CACO-2: 26.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.5"	"Group enriched"	"Detected in many"	9	"NK-cells: 1.5;T-cells: 2.9"	"Low region specificity"	"Detected in all"							"HPA045783, HPA058177, HPA075505"	Uncertain		Approved	"Plasma membrane,Cytosol"				Cytosol	"Plasma membrane"	"HPA045783: AB_10960058, HPA058177: , HPA075505: "	"unprognostic (1.22e-1)"	"prognostic unfavourable (1.07e-5)"	"unprognostic (3.26e-2)"	"unprognostic (1.44e-1)"	"unprognostic (9.03e-2)"	"unprognostic (1.99e-1)"	"unprognostic (2.61e-2)"	"unprognostic (4.85e-2)"	"unprognostic (3.14e-2)"	"unprognostic (1.08e-1)"	"prognostic favourable (6.07e-5)"	"unprognostic (5.34e-3)"	"unprognostic (1.21e-1)"	"unprognostic (3.97e-3)"	"unprognostic (2.78e-1)"	"unprognostic (2.93e-1)"	"unprognostic (6.21e-2)"	26.6	9.6	4.6	5.3	7.9	0.2	27.1	5.9	8.7	6.4	17.5	10.5	5.0	15.4	10.1	8.7	6.9	7.9	8.0	18.0	6.2	2.3	17.5	34.9	19.6	9.2	9.5	6.2	9.0	10.9	4.5	6.3	30.2	7.0	6.7	5.2	11.2	5.9	7.6	19.9	7.1	13.1	8.9	7.1	3.5	6.5	4.0	7.6	0.2	15.4	5.9	3.1	9.7	7.7	0.0	0.1	0.0	0.2	1.5	2.9	0.8	0.0	1.4	5.0	8.0	13.5	5.2	10.1	5.4	9.9	7.8	7.1	26.4	0.1	0.0	5.7	5.4	0.4	6.0	6.6	6.1	0.0	5.4	0.0	0.0	8.3	8.6	0.0	2.2	9.1	2.4	5.4	3.0	6.7	5.4	0.5	7.9	3.4	10.2	0.0	4.5	2.9	0.0	3.8	0.8	4.8	5.1	4.1	5.2	0.0	3.2	4.6	3.4	1.0	10.4	7.9	6.8	5.1	2.8	0.0	1.0	0.0	0.9	0.0	2.8	0.0	0.1	0.0	1.2	0.0	0.0	0.0	0.6	0.5	0.1	0.0	2.9	2.5	0.0	1.5	0.2	0.0	0.0	0.8	4.6	7.9	5.9	8.7	6.2	2.3	9.5	6.2	7.0	7.6
MVD	MPD	ENSG00000167508	"Mevalonate diphosphate decarboxylase"	P53602	16	88651935-88663161	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041404, HPA048250"	Uncertain		Approved	"Cell Junctions,Cytosol"			30000	Cytosol	"Cell Junctions"	"HPA041404: , HPA048250: "	"unprognostic (1.67e-1)"	"unprognostic (3.05e-1)"	"unprognostic (2.42e-1)"	"prognostic favourable (2.17e-4)"	"unprognostic (1.89e-1)"	"unprognostic (9.56e-2)"	"unprognostic (9.26e-3)"	"unprognostic (8.33e-2)"	"unprognostic (6.68e-2)"	"unprognostic (5.47e-2)"	"unprognostic (2.51e-1)"	"unprognostic (6.22e-2)"	"unprognostic (1.19e-3)"	"unprognostic (4.12e-2)"	"unprognostic (1.69e-1)"	"unprognostic (2.11e-1)"	"unprognostic (5.00e-2)"	11.9	18.5	15.8	16.9	19.7	7.6	12.5	21.7	27.9	10.8	19.4	17.1	10.8	39.6	8.4	7.3	30.0	7.4	8.7	11.9	17.2	18.2	9.2	25.9	14.6	12.6	14.6	17.3	11.1	19.0	11.0	7.8	7.6	24.5	13.7	5.1	10.8	16.1	8.7	27.8	18.3	20.7	6.6	23.8	11.1	21.2	23.0	14.6	4.3	9.2	18.6	12.2	7.3	13.8	15.0	17.6	2.5	8.9	18.1	18.1	9.4	14.6	9.4	15.7	10.2	5.3	11.8	8.9	7.3	7.6	5.0	4.2	24.8	37.1	7.1	11.7	4.3	21.8	7.0	38.6	1.4	4.4	11.9	5.2	5.2	37.7	10.8	3.3	3.7	9.3	7.4	13.2	4.2	5.3	14.4	3.9	2.7	34.2	11.1	16.8	18.9	9.2	11.7	4.5	18.3	14.6	9.2	15.9	5.3	18.1	4.1	5.3	20.6	14.8	11.3	4.6	9.4	8.2	4.1	10.8	4.8	24.2	5.6	16.2	7.6	2.5	8.2	1.5	18.1	8.6	13.5	10.3	12.1	11.9	9.5	15.0	9.4	11.5	1.1	18.1	8.9	17.6	12.6	9.4	15.8	19.7	21.7	27.9	17.2	18.2	14.6	17.3	24.5	14.6
NAXD	"CARKD, FLJ10769, LP3298"	ENSG00000213995	"NAD(P)HX dehydratase"	Q8IW45	13	110615460-110639993	"Enzymes, Predicted intracellular proteins"		Lyase	"Disease mutation, Neurodegeneration"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA010551	Uncertain						230000			"HPA010551: AB_1848669"	"unprognostic (1.24e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.79e-2)"	"prognostic favourable (3.15e-4)"	"unprognostic (1.78e-1)"	"unprognostic (1.81e-1)"	"unprognostic (3.48e-2)"	"unprognostic (2.89e-1)"	"unprognostic (3.20e-1)"	"unprognostic (9.01e-2)"	"unprognostic (1.94e-2)"	"unprognostic (4.36e-3)"	"prognostic favourable (4.63e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.62e-2)"	9.1	22.8	17.3	10.9	20.5	4.6	12.5	20.4	25.0	11.5	17.2	19.0	18.0	11.6	13.9	15.3	16.3	14.0	13.6	14.7	20.9	12.0	14.3	30.4	12.1	11.7	15.0	19.4	28.8	24.8	12.7	15.2	14.7	14.8	16.5	12.4	12.7	12.7	21.2	15.1	20.8	12.6	13.7	13.8	13.2	16.7	17.9	17.0	9.2	15.5	10.5	9.9	12.7	11.8	7.3	7.6	0.7	6.9	6.2	8.5	6.1	10.9	5.0	8.3	6.4	10.8	6.6	14.3	8.5	8.0	9.3	9.7	17.1	11.3	2.0	9.3	6.6	9.1	4.7	8.9	4.5	8.3	10.5	7.1	15.7	9.5	10.5	9.4	6.7	9.3	16.5	5.9	6.6	9.8	6.0	0.1	7.3	11.9	6.9	18.0	7.5	6.1	2.3	3.2	2.5	9.9	9.4	14.5	8.6	4.9	26.3	5.9	12.0	15.7	5.7	6.3	5.2	0.1	6.7	7.7	5.2	0.1	10.1	2.1	8.2	0.0	5.9	0.5	8.5	6.9	5.4	7.3	7.7	7.6	7.4	6.5	8.3	8.2	0.7	6.2	4.5	7.6	8.4	6.1	17.3	20.5	20.4	25.0	20.9	12.0	15.0	19.4	14.8	17.0
NEIL1	"FLJ22402, FPG1, hFPG1, NEI1"	ENSG00000140398	"Nei like DNA glycosylase 1"	Q96FI4	15	75346955-75357114	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"Daudi: 11.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"gdT-cell: 4.7;memory B-cell: 4.0;naive B-cell: 6.5;NK-cell: 14.1"	"Group enriched"	"Detected in many"	12	"B-cells: 6.5;NK-cells: 14.1;T-cells: 4.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054084	Approved		Supported	Nucleoplasm				Nucleoplasm		"HPA054084: "	"unprognostic (9.84e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.15e-2)"	"unprognostic (4.62e-3)"	"unprognostic (3.21e-2)"	"unprognostic (1.81e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.17e-3)"	"unprognostic (1.67e-1)"	"unprognostic (1.33e-1)"	"prognostic favourable (2.09e-4)"	"unprognostic (3.50e-3)"	"unprognostic (8.60e-2)"	"unprognostic (9.24e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.03e-1)"	"unprognostic (2.27e-3)"	7.1	14.8	12.9	28.2	14.5	6.8	9.3	24.4	15.4	10.8	8.3	4.9	23.2	10.1	8.4	11.6	6.4	10.0	10.2	5.3	12.8	5.7	7.9	9.1	9.3	9.8	6.0	9.8	11.0	10.8	9.1	9.0	4.6	8.0	10.4	2.4	7.1	25.0	24.2	13.6	11.7	9.5	4.3	5.9	6.8	9.9	3.8	7.0	15.4	8.2	5.2	13.3	7.5	8.5	6.5	0.2	0.7	0.5	14.1	4.7	1.0	2.1	3.6	2.4	1.5	0.7	0.8	4.5	1.3	0.0	0.5	0.1	0.6	4.0	11.4	2.1	0.2	6.3	1.4	0.4	0.0	5.6	9.3	1.9	9.9	1.8	0.9	2.2	2.7	0.3	1.8	0.6	0.0	1.4	1.2	3.4	0.4	2.9	0.4	6.2	2.1	0.8	2.1	1.4	0.5	2.1	2.4	1.4	2.8	2.2	1.0	3.1	4.2	3.3	6.2	1.3	2.5	1.9	1.1	5.3	5.2	9.3	1.2	9.3	1.2	0.0	0.5	0.0	4.7	0.1	1.3	4.0	0.8	1.0	0.2	6.5	1.4	1.4	0.7	14.1	0.1	0.2	0.2	1.0	12.9	14.5	24.4	15.4	12.8	5.7	6.0	9.8	8.0	7.0
NEIL2	"FLJ31644, MGC2832, MGC4505, NEH2"	ENSG00000154328	"Nei like DNA glycosylase 2"	Q969S2	8	11769639-11787346	"Enzymes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA073029, HPA073916"			Supported	Nucleoplasm,Vesicles				Nucleoplasm	Vesicles	"HPA073029: , HPA073916: "	"unprognostic (1.52e-2)"	"unprognostic (1.08e-2)"	"unprognostic (1.03e-1)"	"unprognostic (9.88e-2)"	"unprognostic (2.18e-2)"	"unprognostic (5.72e-2)"	"unprognostic (2.70e-1)"	"unprognostic (2.88e-2)"	"unprognostic (5.46e-2)"	"unprognostic (6.85e-2)"	"unprognostic (1.99e-3)"	"unprognostic (1.29e-1)"	"unprognostic (1.12e-2)"	"unprognostic (5.29e-2)"	"unprognostic (1.91e-1)"	"unprognostic (2.09e-1)"	"unprognostic (4.05e-1)"	10.2	21.8	18.7	6.8	17.7	2.7	10.3	11.8	20.9	11.3	5.6	9.0	7.0	3.6	9.9	15.4	6.5	17.9	6.9	14.2	15.4	20.0	9.3	11.0	7.7	8.4	18.4	16.1	12.6	10.9	7.8	13.2	7.6	20.3	10.5	6.1	9.7	11.5	10.3	24.7	18.1	4.6	10.2	12.3	9.5	5.1	26.8	13.3	1.8	15.5	7.1	7.9	7.4	15.8	14.7	5.5	0.8	2.5	9.1	13.6	4.7	5.1	14.5	9.1	17.7	4.4	8.1	4.1	8.2	6.8	8.0	5.5	4.4	5.6	2.0	3.2	9.8	4.5	8.6	9.0	11.0	6.0	4.3	7.1	3.4	8.6	3.5	3.0	5.3	7.2	13.3	6.9	6.4	7.4	9.9	6.9	9.4	5.4	0.5	3.2	8.1	7.8	8.9	11.7	5.5	9.2	7.7	14.0	11.1	6.4	3.4	11.6	5.4	0.5	9.1	9.1	13.1	2.4	11.4	6.5	13.5	3.6	23.9	10.5	18.4	0.4	1.5	0.1	9.1	2.5	12.1	14.7	9.3	10.8	3.0	11.4	13.6	12.0	0.8	9.1	1.1	5.5	5.8	4.7	18.7	17.7	11.8	19.8	15.4	20.0	18.4	16.1	20.3	13.3
NEIL3	"FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3"	ENSG00000109674	"Nei like DNA glycosylase 3"	Q8TAT5	4	177309836-177362943	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"lymphoid tissue: 70.8"	"Cell line enhanced"	"Detected in many"		"HDLM-2: 26.5;HL-60: 28.8;Karpas-707: 37.9;MOLT-4: 29.2"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low cell type specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA065761			Enhanced	Nucleoplasm				Nucleoplasm		"HPA065761: "	"unprognostic (6.03e-2)"	"unprognostic (5.79e-2)"	"unprognostic (1.42e-1)"	"prognostic unfavourable (5.45e-4)"	"unprognostic (4.91e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.64e-7)"	"prognostic unfavourable (1.16e-4)"	"unprognostic (6.09e-3)"	"unprognostic (7.67e-2)"	"unprognostic (6.51e-4)"	"unprognostic (2.82e-3)"	"unprognostic (0.00e+0)"	"unprognostic (3.25e-2)"	"unprognostic (8.13e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.04e-2)"	0.5	0.4	0.2	7.4	0.2	9.3	0.7	0.1	0.2	0.8	1.5	0.1	0.1	1.5	0.5	0.1	5.6	0.2	0.3	0.5	0.2	0.2	0.4	0.4	0.9	5.1	0.2	0.1	0.3	0.2	0.0	0.2	1.6	0.2	0.2	2.1	0.2	0.8	0.1	0.2	3.4	1.7	0.5	0.7	1.5	0.8	3.5	0.3	70.8	0.2	1.1	5.0	0.7	1.3	0.2	0.3	0.8	0.0	1.6	1.6	0.2	7.0	5.9	6.3	3.1	0.7	1.3	3.1	8.8	3.2	9.8	5.8	2.1	6.2	7.8	1.3	2.3	3.3	6.6	3.5	14.2	26.5	4.3	5.4	4.6	5.6	0.2	28.8	3.7	0.1	0.2	10.1	2.2	3.7	5.5	37.9	6.3	3.1	29.2	11.1	2.9	4.3	5.9	4.3	2.5	2.5	0.9	4.9	3.4	4.4	5.1	2.4	4.1	7.5	1.7	5.9	4.6	3.0	8.8	2.6	1.7	12.4	3.9	10.3	9.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	1.3	0.0	0.2	0.0	1.1	0.8	1.6	0.0	0.3	1.6	0.2	0.2	0.2	0.1	0.2	0.2	0.2	0.2	0.1	0.2	0.3
NPL	"C1orf13, DHDPS1, NPL1"	ENSG00000135838	"N-acetylneuraminate pyruvate lyase"	Q9BXD5	1	182789293-182830384	"Enzymes, Predicted intracellular proteins"	"Carbohydrate metabolism"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"blood: 76.0"	"Cell line enhanced"	"Detected in many"		"Karpas-707: 11.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 76.0"	"Group enriched"	"Detected in many"	36	"granulocytes: 76.0;monocytes: 23.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA028345, HPA075808"	Enhanced		Approved	"Vesicles,Plasma membrane"			190000	Vesicles	"Plasma membrane"	"HPA028345: AB_10610145, HPA075808: "	"unprognostic (2.43e-2)"	"unprognostic (5.71e-3)"	"unprognostic (1.72e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.57e-1)"	"unprognostic (3.06e-1)"	"prognostic unfavourable (8.05e-4)"	"unprognostic (4.41e-2)"	"unprognostic (6.54e-3)"	"unprognostic (1.45e-1)"	"unprognostic (1.49e-1)"	"unprognostic (6.18e-2)"	"prognostic unfavourable (6.63e-4)"	"unprognostic (2.11e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.35e-2)"	"unprognostic (7.44e-2)"	14.9	6.8	10.9	14.2	12.3	12.4	5.3	3.5	10.2	3.9	5.3	15.0	11.4	2.4	2.5	23.7	8.0	4.1	10.1	4.7	9.2	8.7	37.4	15.4	14.3	20.4	16.0	8.6	2.8	3.2	2.5	2.5	32.9	15.4	4.4	7.4	3.9	5.7	5.8	2.4	6.5	4.8	5.8	15.3	32.1	4.0	4.0	14.4	3.1	3.4	1.3	10.9	11.8	5.5	0.7	1.3	76.0	23.6	0.0	1.3	10.3	2.7	0.5	0.8	0.0	2.4	2.4	0.7	0.9	1.8	1.0	0.5	0.0	1.2	7.3	1.3	0.0	1.1	1.6	2.0	0.2	0.0	1.2	11.6	0.3	0.1	1.3	4.3	6.9	1.9	7.7	0.2	0.0	0.1	8.7	11.7	1.8	0.9	0.2	2.9	9.3	0.9	1.1	0.6	8.9	0.2	6.1	2.6	3.9	4.2	0.2	3.7	2.4	7.1	0.2	1.0	2.0	0.6	0.1	8.4	10.1	7.4	2.1	7.8	3.0	3.6	23.6	18.0	1.0	20.8	0.9	0.3	0.8	0.9	1.3	0.7	0.7	0.9	76.0	0.0	16.0	0.2	1.3	10.3	10.9	12.3	3.5	10.2	9.2	8.7	16.0	8.6	15.4	14.4
NPR1	"ANPa, ANPRA, GUCY2A, NPRA"	ENSG00000169418	"Natriuretic peptide receptor 1"	P16066	1	153678637-153693992	"Enzymes, FDA approved drug targets, Predicted membrane proteins"	"cGMP biosynthesis"	"Lyase, Receptor, Vasoactive"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 98.4"	"Cell line enriched"	"Detected in some"	6	"ASC diff: 59.1"	"Cancer enhanced"	"Detected in all"		"ovarian cancer: 39.2"	"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Region enriched"	"Detected in many"	5	"olfactory region: 23.0"	"Region enhanced"	"Detected in many"		"olfactory region: 11.1"	HPA031087			Approved	"Nucleoplasm,Nucleoli,Plasma membrane"				Nucleoli	"Nucleoplasm, Plasma membrane"	"HPA031087: AB_10601975"	"unprognostic (2.54e-1)"	"unprognostic (3.03e-3)"	"unprognostic (6.31e-2)"	"prognostic unfavourable (3.97e-4)"	"unprognostic (1.55e-1)"	"unprognostic (6.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.03e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.27e-2)"	"prognostic favourable (2.49e-4)"	"unprognostic (1.27e-1)"	"unprognostic (6.69e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.06e-1)"	"unprognostic (1.74e-2)"	41.1	4.3	0.5	5.9	0.9	0.1	98.4	0.5	0.8	8.1	8.2	0.3	7.3	1.2	16.8	11.1	8.7	25.0	9.3	19.6	0.9	0.5	28.7	3.7	34.8	8.6	0.7	0.0	19.5	4.2	7.8	4.5	11.8	2.5	4.9	1.5	2.0	2.0	9.0	6.9	3.4	4.6	15.6	2.2	1.2	5.0	6.4	0.2	0.8	7.6	5.1	1.1	11.6	26.5	0.0	0.5	0.0	0.3	0.0	0.0	0.0	0.0	0.4	0.0	0.0	59.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	9.8	0.0	7.1	0.0	0.0	0.1	0.0	0.1	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	5.5	0.0	0.0	0.7	0.0	0.0	0.0	0.6	0.0	2.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.9	0.5	0.8	0.9	0.5	0.7	0.0	2.5	0.2
NPR2	"AMDM, ANPb, ANPRB, GUCY2B, NPRB"	ENSG00000159899	"Natriuretic peptide receptor 2"	P20594	9	35792154-35809732	"Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"cGMP biosynthesis, Osteogenesis"	"Lyase, Receptor"	"Disease mutation, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 32.7"	"Cell line enhanced"	"Detected in many"		"ASC diff: 27.2;ASC TERT1: 20.3;BJ hTERT+: 16.6;HSkMC: 20.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"plasmacytoid DC: 3.1"	"Group enriched"	"Detected in many"	6	"dendritic cells: 3.1;T-cells: 2.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"														"unprognostic (2.93e-2)"	"unprognostic (8.22e-3)"	"unprognostic (9.25e-3)"	"unprognostic (3.59e-2)"	"unprognostic (6.13e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.56e-1)"	"unprognostic (2.40e-1)"	"unprognostic (3.06e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.99e-2)"	"unprognostic (6.99e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.24e-1)"	"unprognostic (7.86e-2)"	9.0	4.8	3.8	1.9	6.4	0.0	7.2	32.7	11.2	29.2	7.8	1.8	4.4	1.8	22.6	9.8	5.3	7.6	5.7	7.6	3.7	4.2	3.7	8.4	4.7	2.3	2.5	5.1	8.0	1.3	2.7	7.9	7.1	11.8	8.3	4.0	8.3	3.3	9.5	7.7	6.2	3.7	17.1	3.9	2.6	4.5	5.5	4.0	0.9	3.2	2.4	2.0	6.2	8.9	0.4	3.1	0.0	0.0	0.1	2.1	0.1	0.0	1.6	1.9	0.0	27.2	20.3	1.2	7.5	16.6	6.1	6.6	4.0	2.7	1.1	2.0	14.7	0.7	2.3	0.2	5.5	1.2	0.7	1.0	1.7	1.9	14.8	0.1	0.0	20.1	1.1	6.8	0.5	10.0	0.5	0.1	11.4	0.5	0.3	0.4	2.5	2.8	1.3	0.1	0.5	0.9	0.8	0.5	0.6	0.2	0.0	0.3	0.1	0.0	6.4	6.5	5.0	2.1	0.7	0.2	0.3	2.9	8.3	0.3	3.6	0.0	0.0	0.0	1.1	0.0	0.0	0.4	1.2	0.6	0.0	0.0	0.5	0.4	0.0	0.1	0.0	3.1	2.1	0.1	3.8	6.4	32.7	11.2	3.7	4.2	2.5	5.1	11.8	4.0
NTHL1	"NTH1, OCTS3"	ENSG00000065057	"Nth like DNA glycosylase 1"	P78549	16	2039815-2047866	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Glycosidase, Hydrolase, Lyase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB025152	Supported									"CAB025152: "	"unprognostic (1.06e-1)"	"unprognostic (9.71e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.54e-1)"	"unprognostic (7.89e-2)"	"unprognostic (1.77e-1)"	"unprognostic (2.86e-1)"	"unprognostic (2.46e-2)"	"unprognostic (4.98e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.77e-2)"	"unprognostic (6.78e-2)"	"unprognostic (6.53e-2)"	"unprognostic (2.27e-1)"	"unprognostic (1.34e-1)"	"unprognostic (5.08e-2)"	"unprognostic (1.62e-2)"	10.5	8.2	13.4	10.5	19.9	6.0	7.8	15.6	17.9	14.8	12.3	9.0	15.1	9.7	11.8	6.9	9.4	20.5	14.7	10.6	12.5	12.1	7.4	17.5	11.1	10.4	13.6	15.7	18.8	24.6	5.8	8.7	8.3	13.3	9.8	8.2	9.1	22.2	18.2	12.4	6.3	11.2	7.8	10.4	15.2	11.1	6.4	11.6	9.6	9.5	6.6	8.4	7.8	9.3	21.4	14.7	2.4	14.2	9.7	18.8	8.5	10.7	26.4	7.7	11.6	3.1	6.0	8.5	4.5	4.8	8.6	5.4	18.8	10.5	22.9	9.5	3.7	9.6	9.5	10.6	1.5	10.6	23.3	7.1	16.7	20.8	4.3	8.1	8.4	5.0	5.5	4.5	4.9	11.9	7.7	8.3	3.3	12.0	12.1	30.4	17.1	17.3	29.0	8.1	36.7	6.2	3.9	16.3	16.3	4.9	15.1	8.7	10.8	8.0	4.6	7.3	8.1	6.5	8.3	11.3	13.2	9.3	3.3	11.4	9.1	2.4	8.7	2.0	8.8	14.2	9.8	21.4	10.5	9.8	14.7	17.1	7.8	9.5	0.3	9.7	12.1	14.6	18.8	8.5	13.4	19.9	15.6	17.9	12.5	12.1	13.6	15.7	13.3	11.6
ODC1	ODC	ENSG00000115758	"Ornithine decarboxylase 1"	P11926	2	10439968-10448504	"Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins"	"Polyamine biosynthesis"	"Decarboxylase, Lyase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001536, CAB035996"	Approved		Approved	"Plasma membrane,Cytosol"				"Plasma membrane, Cytosol"		"CAB035996: , HPA001536: AB_1079521"	"unprognostic (2.33e-1)"	"unprognostic (3.41e-1)"	"unprognostic (7.25e-3)"	"unprognostic (5.21e-3)"	"unprognostic (4.22e-2)"	"unprognostic (2.70e-1)"	"prognostic unfavourable (3.07e-5)"	"unprognostic (3.06e-2)"	"unprognostic (4.18e-2)"	"unprognostic (6.27e-2)"	"unprognostic (3.04e-1)"	"unprognostic (6.65e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.18e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.26e-2)"	"unprognostic (5.86e-2)"	13.2	8.2	11.6	33.5	11.1	41.8	9.1	7.2	11.8	11.7	17.4	11.5	33.8	8.6	22.9	21.6	16.5	16.5	30.0	33.8	9.7	10.6	31.5	48.7	14.2	42.3	11.3	6.5	29.2	48.7	13.4	35.4	6.9	11.2	26.3	20.7	18.2	11.0	27.2	64.2	9.6	14.9	26.2	10.2	20.4	19.2	54.6	6.3	31.0	16.4	19.8	39.6	16.1	14.6	13.4	10.8	2.4	2.4	1.2	4.4	3.0	18.6	15.0	20.9	24.7	3.7	11.2	48.5	27.0	13.4	25.6	11.9	79.7	8.7	98.9	13.6	16.5	3.4	63.9	30.7	31.2	37.6	26.7	45.1	25.8	48.6	30.4	76.2	10.8	7.5	8.3	57.9	72.7	20.5	75.0	32.2	14.2	12.3	75.4	30.0	38.1	49.0	53.8	65.7	66.6	15.5	13.7	29.2	24.9	33.9	10.4	13.7	7.0	34.2	14.3	20.8	42.9	26.8	58.0	15.0	45.4	89.9	18.7	50.5	12.8	0.0	1.3	2.4	2.7	2.4	3.2	13.4	3.8	4.4	3.0	11.0	2.7	4.3	0.5	1.2	1.5	10.8	3.8	3.0	11.6	11.1	7.2	11.8	9.7	10.6	11.3	6.5	11.2	6.3
OGG1	"HMMH, HOGG1, MUTM, OGH1"	ENSG00000114026	"8-oxoguanine DNA glycosylase"	O15527	3	9749944-9788219	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Glycosidase, Hydrolase, Lyase, Multifunctional enzyme"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027514, CAB047301"	Approved		Enhanced	Nucleoplasm				Nucleoplasm		"CAB047301: , HPA027514: AB_10602189"	"unprognostic (6.95e-2)"	"unprognostic (7.82e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.24e-3)"	"unprognostic (9.69e-2)"	"unprognostic (1.97e-2)"	"prognostic unfavourable (5.77e-5)"	"unprognostic (7.83e-2)"	"unprognostic (2.45e-2)"	"unprognostic (3.43e-3)"	"unprognostic (9.66e-3)"	"unprognostic (4.23e-2)"	"prognostic favourable (2.65e-4)"	"unprognostic (2.06e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.65e-1)"	"unprognostic (1.59e-1)"	10.4	12.9	15.4	28.5	16.2	12.7	11.5	22.0	17.7	16.7	18.8	16.2	10.5	22.0	16.2	13.1	10.0	14.7	12.1	10.7	14.7	10.8	30.1	17.8	9.9	28.5	12.3	14.1	22.5	12.0	5.8	10.2	10.3	15.3	14.4	10.2	14.6	14.3	13.2	7.4	11.5	28.2	12.1	13.6	14.1	10.8	7.3	15.6	19.8	12.2	6.3	25.5	12.2	13.3	12.2	11.9	15.4	8.5	19.4	15.4	8.3	5.7	10.7	10.9	6.8	10.7	12.3	20.1	7.5	7.7	11.5	13.8	10.3	5.7	35.0	5.0	9.5	5.6	6.4	8.2	4.9	12.4	9.2	17.4	17.3	14.7	11.3	6.7	11.2	12.2	10.5	19.9	8.5	14.2	5.5	5.7	10.9	10.7	5.4	6.7	5.7	15.4	4.0	7.3	11.4	6.4	2.9	4.9	8.6	9.6	7.8	5.8	12.4	11.5	9.2	11.7	12.4	9.1	12.2	5.7	8.1	18.0	9.4	19.5	7.2	11.3	8.5	15.4	15.1	6.6	14.6	10.4	13.0	12.3	7.6	12.2	10.2	9.6	2.1	19.4	5.3	11.9	15.4	8.3	15.4	16.2	22.0	17.7	14.7	10.8	12.3	14.1	15.3	15.6
PAICS	"ADE2H1, AIRC, PAIS"	ENSG00000128050	"Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase"	P22234	4	56435741-56464579	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	"Decarboxylase, Ligase, Lyase, Multifunctional enzyme"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035895, HPA041538"	Uncertain		Approved	Cytosol			340000	Cytosol		"HPA035895: AB_10669660, HPA041538: AB_2677540"	"unprognostic (2.59e-3)"	"unprognostic (7.90e-3)"	"unprognostic (3.84e-3)"	"unprognostic (2.88e-2)"	"unprognostic (9.85e-2)"	"unprognostic (2.82e-3)"	"prognostic unfavourable (1.50e-4)"	"unprognostic (8.07e-3)"	"unprognostic (1.23e-2)"	"prognostic favourable (8.44e-4)"	"unprognostic (1.48e-3)"	"unprognostic (2.05e-1)"	"prognostic unfavourable (5.85e-5)"	"unprognostic (7.11e-2)"	"unprognostic (1.67e-1)"	"prognostic unfavourable (2.41e-4)"	"unprognostic (2.16e-1)"	15.5	27.1	21.6	20.4	17.4	21.4	29.3	15.8	20.6	17.5	22.5	18.5	18.4	17.2	19.6	12.6	29.0	19.6	11.4	13.4	16.7	22.6	26.5	63.7	11.3	25.6	26.4	19.2	23.3	27.7	26.2	17.9	24.3	29.8	17.5	30.5	13.1	15.7	16.8	23.8	20.0	16.1	19.4	23.5	19.8	12.8	18.3	15.9	44.9	17.8	26.8	33.1	18.7	18.9	13.7	12.8	3.2	6.4	10.9	14.4	6.7	33.9	25.5	52.8	32.6	11.3	25.6	45.5	29.5	21.4	42.3	41.8	40.5	40.5	78.8	34.3	19.7	21.0	83.2	42.8	72.7	15.7	29.3	42.8	39.1	44.8	21.7	76.0	19.1	21.6	31.1	44.9	34.0	34.7	73.8	29.4	36.4	22.7	87.3	38.1	60.4	32.0	70.9	22.6	51.8	40.1	23.9	56.7	33.9	29.0	40.6	17.8	26.8	24.4	18.6	33.6	43.9	33.0	60.2	20.8	17.8	82.9	35.4	55.7	36.9	3.2	3.7	0.3	4.1	6.4	11.8	13.7	11.5	7.3	11.4	8.9	14.4	12.1	0.9	10.9	4.8	12.8	8.3	6.7	21.6	17.4	15.8	20.6	16.7	22.6	26.4	19.2	29.8	15.9
PAM	"PAL, PHM"	ENSG00000145730	"Peptidylglycine alpha-amidating monooxygenase"	P19021	5	102753981-103031105	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 304.2"	"Cell line enhanced"	"Detected in many"		"ASC diff: 76.6;fHDF/TERT166: 98.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB026119, HPA042260"	Enhanced		Approved	"Golgi apparatus,Cytosol"	"Secreted in other tissues"		59000000	"Golgi apparatus, Cytosol"		"CAB026119: , HPA042260: "	"unprognostic (4.30e-3)"	"unprognostic (1.60e-2)"	"unprognostic (1.12e-1)"	"prognostic favourable (1.63e-4)"	"unprognostic (4.23e-2)"	"unprognostic (6.30e-2)"	"prognostic unfavourable (6.20e-4)"	"unprognostic (7.58e-2)"	"unprognostic (6.62e-2)"	"unprognostic (2.71e-1)"	"unprognostic (9.91e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.08e-1)"	"unprognostic (9.79e-2)"	"unprognostic (5.51e-2)"	"unprognostic (8.80e-3)"	16.5	24.5	8.2	6.5	16.4	0.8	17.3	6.6	16.5	74.9	14.0	5.4	9.5	5.8	21.3	83.8	11.7	10.6	11.5	304.2	8.8	23.5	13.7	2.1	13.2	5.8	10.0	7.6	17.0	16.4	49.5	18.3	26.3	15.5	13.4	9.5	8.7	53.8	29.4	22.0	8.5	8.5	18.5	4.8	8.9	17.2	7.2	4.6	1.8	21.7	13.2	7.3	15.8	15.3	0.5	2.0	10.1	5.3	16.2	14.1	6.3	14.9	2.2	27.6	12.2	76.6	45.9	11.0	42.6	63.8	12.6	38.5	7.3	19.9	0.0	9.2	98.2	5.1	1.5	18.7	34.9	1.8	6.2	3.1	9.0	2.3	11.6	0.9	3.4	25.1	8.1	9.2	7.0	26.0	0.1	2.1	35.7	3.0	0.0	0.4	4.9	8.3	1.1	15.4	8.3	48.7	1.7	13.1	9.0	18.1	1.1	11.1	4.7	1.0	20.0	40.1	10.4	18.8	12.6	4.7	1.1	0.0	46.0	4.2	34.5	1.9	5.3	0.1	14.1	0.9	10.0	0.5	8.5	10.4	2.0	0.3	2.9	4.8	10.1	16.2	1.9	1.1	12.1	6.3	8.2	16.4	6.6	16.5	8.8	23.5	10.0	7.6	15.5	4.6
PCBD1	"DCOH, PCBD, PCD"	ENSG00000166228	"Pterin-4 alpha-carbinolamine dehydratase 1"	P61457	10	70882280-70888784	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation"	"Activator, Lyase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 99.0"	"Cell line enhanced"	"Detected in many"		"CACO-2: 67.5;Hep G2: 66.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037575, HPA061723"	Approved		Enhanced	Nucleoplasm,Cytosol			210000	Nucleoplasm	Cytosol	"HPA037575: AB_10671761, HPA061723: "	"unprognostic (1.02e-1)"	"unprognostic (5.05e-2)"	"unprognostic (7.43e-2)"	"unprognostic (3.69e-1)"	"unprognostic (5.39e-2)"	"unprognostic (4.80e-3)"	"unprognostic (1.81e-1)"	"unprognostic (1.47e-1)"	"unprognostic (2.35e-1)"	"unprognostic (2.40e-2)"	"unprognostic (2.95e-1)"	"unprognostic (5.63e-2)"	"unprognostic (3.38e-2)"	"unprognostic (9.26e-2)"	"unprognostic (1.74e-1)"	"unprognostic (5.76e-2)"	"unprognostic (7.43e-3)"	18.3	25.5	18.1	9.6	15.6	4.3	19.7	13.2	14.8	13.9	18.4	7.8	24.3	12.6	13.9	21.4	26.5	25.6	22.9	32.5	10.8	23.7	38.7	99.0	14.0	7.8	16.7	12.3	18.5	73.0	15.8	15.5	11.7	16.4	26.9	20.3	16.3	16.2	20.7	23.1	5.8	17.2	18.1	14.5	10.2	19.2	7.0	8.7	4.3	36.8	16.2	12.3	22.4	31.8	11.8	20.9	3.5	19.4	8.0	16.9	7.5	20.4	48.5	2.9	30.1	11.0	10.3	3.9	6.6	11.0	10.3	8.2	67.5	36.2	4.2	19.2	7.2	13.6	18.3	10.6	7.0	10.9	33.1	3.7	7.7	66.3	11.6	3.6	13.6	10.0	11.6	10.2	4.8	27.6	7.2	0.3	7.1	34.1	0.4	12.2	4.1	45.4	2.0	4.0	13.4	43.2	21.1	12.7	21.5	5.5	37.6	14.3	10.9	7.1	11.4	1.7	14.4	2.5	16.2	0.1	0.8	0.1	9.4	11.9	2.6	0.0	10.7	3.5	8.8	19.4	6.9	11.8	11.6	12.6	20.9	4.1	3.8	7.9	0.6	8.0	13.3	15.3	16.9	7.5	18.1	15.6	13.2	14.8	10.8	23.7	16.7	12.3	16.4	8.7
PCBD2	"DCOH2, DCOHM"	ENSG00000132570	"Pterin-4 alpha-carbinolamine dehydratase 2"	Q9H0N5	5	134904906-135007959	"Enzymes, Predicted intracellular proteins"	"Tetrahydrobiopterin biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 47.0"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA036428	Uncertain		Approved	"Plasma membrane"				"Plasma membrane"		"HPA036428: AB_10670103"	"unprognostic (3.70e-2)"	"unprognostic (3.53e-2)"	"unprognostic (3.54e-3)"	"unprognostic (1.36e-2)"	"unprognostic (2.92e-1)"	"unprognostic (1.98e-1)"	"unprognostic (4.22e-1)"	"unprognostic (6.43e-2)"	"unprognostic (4.49e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.22e-1)"	"unprognostic (5.18e-2)"	"unprognostic (1.87e-3)"	"unprognostic (4.57e-2)"	"unprognostic (6.34e-2)"	"unprognostic (9.32e-3)"	"unprognostic (1.50e-1)"	4.9	8.1	5.4	7.0	6.6	6.6	5.3	3.0	4.4	3.9	8.7	6.5	9.4	8.0	6.5	8.4	9.3	4.9	6.9	13.8	5.0	5.3	9.2	9.8	6.5	5.0	5.6	5.2	5.1	12.9	9.6	6.1	4.8	6.8	4.7	6.4	9.6	14.2	7.9	47.0	6.7	12.7	7.6	7.0	5.5	7.1	5.5	5.8	5.3	8.3	13.5	8.1	5.6	5.5	8.2	11.5	7.2	10.1	6.3	6.6	4.3	7.7	7.5	8.0	6.0	5.6	4.7	5.9	6.2	4.8	3.5	3.6	13.9	19.8	9.2	10.4	4.2	5.3	5.4	5.9	3.3	12.9	3.6	5.3	7.9	8.3	5.4	6.0	3.8	2.5	5.8	3.7	8.5	4.1	7.6	13.9	6.2	15.9	6.3	10.2	4.5	7.3	10.0	7.5	8.2	6.5	6.5	6.0	7.9	9.3	4.8	7.7	13.4	7.9	4.5	6.8	5.1	5.9	7.8	10.8	14.8	6.3	6.1	7.3	4.4	2.7	10.1	7.2	5.1	6.3	5.0	8.2	6.3	5.3	8.6	8.2	5.4	5.3	3.3	6.3	6.1	11.5	6.6	4.3	5.4	6.6	3.0	4.1	5.0	5.3	5.6	5.2	6.8	5.8
PCK1	PEPCK-C	ENSG00000124253	"Phosphoenolpyruvate carboxykinase 1"	P35558	20	57561080-57568112	"Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	Gluconeogenesis	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"liver: 419.5"	"Cell line enriched"	"Detected in some"	10	"ASC diff: 21.5"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 99.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA006277, HPA006507, CAB017027"	Approved						380000			"CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578"	"unprognostic (3.50e-2)"	"unprognostic (5.60e-2)"	"unprognostic (4.60e-2)"	"unprognostic (8.62e-3)"	"unprognostic (1.99e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.21e-2)"	"unprognostic (4.43e-2)"		"unprognostic (1.84e-1)"	"unprognostic (2.37e-1)"	"unprognostic (1.64e-1)"	"prognostic favourable (1.47e-5)"	"unprognostic (1.03e-1)"	"unprognostic (6.40e-2)"	"unprognostic (1.05e-3)"	"unprognostic (2.21e-1)"	10.0	0.1	0.4	2.2	0.4	0.0	11.1	0.2	0.6	0.1	52.0	0.2	0.1	19.2	0.1	0.7	0.2	0.1	5.6	0.4	0.3	0.2	72.0	419.5	0.2	0.3	0.2	0.2	0.4	0.2	0.0	5.0	0.1	0.5	0.2	14.0	0.2	0.2	0.1	0.3	0.1	58.5	0.4	0.1	0.1	0.1	0.2	0.2	0.1	0.4	0.4	0.3	0.4	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	21.5	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.4	0.3	0.0	0.0	0.1	0.3	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	2.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.4	0.2	0.6	0.3	0.2	0.2	0.2	0.5	0.2
PCK2	"PEPCK, PEPCK2"	ENSG00000100889	"Phosphoenolpyruvate carboxykinase 2, mitochondrial"	Q16822	14	24094053-24110598	"Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Gluconeogenesis	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	5	"intestine: 156.3;liver: 115.1"	"Cell line enhanced"	"Detected in many"		"HHSteC: 34.9;hTCEpi: 33.9;SK-MEL-30: 32.1"	"Cancer enhanced"	"Detected in all"		"liver cancer: 91.3"	"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018734, HPA051162, HPA053502"	Enhanced		Enhanced	Mitochondria			3300000	Mitochondria		"CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171"	"unprognostic (3.38e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.50e-2)"	"unprognostic (4.07e-1)"	"unprognostic (3.11e-1)"	"unprognostic (2.10e-1)"	"prognostic favourable (2.81e-4)"	"unprognostic (3.91e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.18e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.67e-2)"	"unprognostic (1.33e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.71e-1)"	"unprognostic (2.82e-2)"	"unprognostic (1.17e-1)"	8.2	2.5	1.0	4.9	1.9	1.0	4.3	1.3	1.3	1.3	69.7	1.4	6.9	51.8	1.3	8.5	4.5	1.2	4.2	2.6	1.5	1.0	26.4	115.1	6.0	4.4	1.7	1.2	1.8	8.5	3.4	1.7	1.2	1.8	2.0	5.4	1.9	11.5	4.9	1.0	2.7	156.3	1.1	1.7	6.7	3.3	3.9	1.3	1.3	5.8	1.9	4.6	2.8	1.9	8.8	10.8	2.4	15.1	1.5	6.5	3.9	5.4	3.1	0.9	5.8	3.6	3.7	14.8	6.8	8.2	5.7	9.3	5.1	6.3	13.9	0.8	10.5	8.0	6.0	8.8	4.7	7.1	0.2	2.5	1.7	27.2	34.9	4.8	11.0	4.3	33.9	3.6	8.8	4.6	7.1	25.8	2.2	23.7	1.2	2.4	1.0	4.1	2.8	3.4	7.9	1.7	8.5	3.7	5.9	5.2	6.8	32.1	9.1	7.5	0.8	1.2	6.6	1.8	1.9	17.7	5.5	3.4	3.5	7.7	3.0	0.1	8.2	2.4	3.1	15.1	3.4	8.8	3.5	3.5	10.8	6.1	2.2	2.0	1.0	1.5	14.4	1.9	6.5	3.9	1.0	1.9	1.3	1.3	1.5	1.0	1.7	1.2	1.8	1.3
PHYKPL	"AGXT2L2, MGC15875"	ENSG00000175309	"5-phosphohydroxy-L-lysine phospho-lyase"	Q8IUZ5	5	178208497-178232791	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA036461, HPA063608"	Approved		Approved	Mitochondria			190000	Mitochondria		"HPA036461: AB_10670717, HPA063608: "	"unprognostic (3.29e-3)"	"unprognostic (2.60e-1)"	"unprognostic (5.51e-2)"	"unprognostic (9.75e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.24e-1)"	"unprognostic (1.06e-2)"	"unprognostic (1.68e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.38e-2)"	"unprognostic (1.02e-3)"	"prognostic unfavourable (3.82e-5)"	"unprognostic (3.66e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.02e-1)"	"unprognostic (2.41e-3)"	18.7	13.1	10.5	25.0	10.8	9.8	15.5	8.3	10.9	13.9	24.3	13.4	14.4	15.1	13.5	14.9	10.7	13.6	17.5	15.5	8.9	4.9	18.1	44.4	14.7	16.8	13.7	9.3	13.2	18.0	11.9	11.9	11.8	10.2	12.4	23.9	12.1	12.3	13.7	20.2	7.6	29.8	14.1	10.7	20.2	15.3	16.4	11.7	16.3	16.6	10.5	17.4	14.0	11.8	13.9	32.8	16.7	21.7	10.7	14.0	14.3	5.7	2.4	5.7	2.3	14.4	11.4	8.6	3.6	4.0	4.8	7.7	6.1	7.3	7.5	10.9	11.0	3.7	4.9	9.2	5.6	15.3	4.9	9.6	9.6	4.3	23.4	5.4	6.1	13.1	9.7	6.0	14.8	16.0	6.9	17.3	7.2	8.4	7.5	2.8	1.1	7.9	5.0	2.7	15.0	8.8	5.2	3.5	3.3	5.7	3.3	6.0	3.6	4.4	6.4	5.0	4.6	3.2	3.8	11.1	3.0	4.5	1.4	5.8	3.3	6.3	19.5	16.7	10.0	21.7	10.1	13.9	11.3	11.4	25.2	12.6	14.0	11.3	4.4	10.7	21.3	32.8	12.9	14.3	10.5	10.8	8.3	10.9	8.9	4.9	13.7	9.3	10.2	11.7
PISD	"dJ858B16.2, PSDC"	ENSG00000241878	"Phosphatidylserine decarboxylase"	Q9UG56	22	31618491-31662432	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MCF7: 39.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			"HPA031090, HPA031091"	Approved		Approved	"Golgi apparatus,Cytosol"				"Golgi apparatus, Cytosol"		"HPA031090: AB_10600114, HPA031091: AB_10600893"	"unprognostic (7.96e-2)"	"unprognostic (5.41e-3)"	"unprognostic (2.60e-1)"	"unprognostic (8.31e-2)"	"unprognostic (5.61e-2)"	"unprognostic (4.55e-3)"	"unprognostic (2.44e-3)"	"unprognostic (8.13e-3)"	"unprognostic (6.37e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.11e-3)"	"unprognostic (1.70e-2)"	"unprognostic (4.18e-3)"	"unprognostic (1.91e-2)"	"unprognostic (4.85e-2)"	"unprognostic (3.92e-2)"	"prognostic favourable (5.27e-5)"	38.3	12.3	9.5	15.1	10.9	20.9	18.5	34.5	12.3	5.9	7.3	6.2	7.4	11.4	9.6	14.4	7.0	10.0	9.5	6.9	6.4	6.9	11.9	8.4	12.9	14.6	8.3	10.1	7.5	10.9	6.0	11.7	38.1	8.6	8.2	3.3	7.7	7.9	7.9	6.4	10.2	8.0	6.2	5.8	16.5	9.7	17.8	7.7	4.2	10.6	5.3	9.8	6.2	7.0	6.9	11.0	28.6	12.9	5.7	6.8	7.9	10.4	9.6	2.9	2.9	8.9	3.4	6.7	8.5	6.8	6.0	6.5	13.9	3.3	6.3	9.1	4.3	11.8	3.9	7.6	1.0	6.9	8.4	6.6	5.9	11.4	18.5	13.7	17.3	6.4	4.3	10.7	4.6	5.3	19.0	3.7	3.4	39.0	5.9	5.9	2.8	4.0	8.4	3.2	6.3	3.8	9.2	7.2	4.2	4.9	16.0	5.5	13.2	7.5	10.3	7.6	9.0	4.8	7.9	4.5	6.2	7.8	7.2	9.2	6.0	9.9	12.9	9.3	6.8	9.5	6.5	6.9	4.9	5.7	11.0	6.3	6.7	5.5	28.6	5.7	5.0	5.4	4.7	7.9	9.5	10.9	34.5	12.3	6.4	6.9	8.3	10.1	8.6	7.7
PPCDC	"FLJ14585, MDS018"	ENSG00000138621	"Phosphopantothenoylcysteine decarboxylase"	Q96CD2	15	75023555-75117462	"Enzymes, Predicted intracellular proteins"	"Coenzyme A biosynthesis"	"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Karpas-707: 53.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"dendritic cells: 19.9;granulocytes: 40.4;monocytes: 18.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045667	Approved		Approved	Cytosol				Cytosol		"HPA045667: AB_2679412"	"unprognostic (8.66e-2)"	"unprognostic (1.07e-3)"	"unprognostic (6.03e-2)"	"unprognostic (2.57e-2)"	"unprognostic (2.95e-2)"	"unprognostic (6.53e-2)"	"unprognostic (1.76e-2)"	"unprognostic (8.40e-2)"	"unprognostic (1.72e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.60e-2)"	"unprognostic (7.67e-2)"	"unprognostic (1.73e-1)"	"unprognostic (3.43e-1)"	"unprognostic (2.13e-3)"	10.4	18.5	7.7	11.1	9.3	16.7	14.5	10.8	10.2	8.4	10.8	16.0	15.1	9.4	16.3	13.3	17.5	10.9	12.1	7.8	7.3	7.9	12.5	12.0	13.9	14.0	16.8	5.9	9.2	22.1	14.4	11.3	8.9	11.0	12.0	9.3	15.6	17.5	8.0	10.5	8.3	11.6	6.1	13.6	18.0	10.7	9.7	11.3	7.4	11.0	11.5	16.5	14.2	9.4	4.2	19.9	40.4	18.1	4.5	5.6	4.2	5.9	11.2	4.7	3.6	2.8	2.6	4.0	6.0	2.7	8.1	6.4	6.5	16.2	6.8	10.8	3.0	6.2	7.6	10.0	4.2	23.8	9.2	11.9	6.9	7.0	8.1	6.9	15.5	3.5	6.7	8.3	12.8	6.4	8.0	53.0	5.8	11.4	4.1	10.7	7.5	5.2	6.9	9.2	14.5	6.1	8.6	11.3	3.3	8.8	12.4	12.9	15.3	9.0	3.6	8.3	5.8	4.2	10.6	16.2	10.6	11.2	5.1	17.6	9.3	10.9	6.5	40.4	3.4	17.5	5.6	4.2	3.1	3.8	4.9	2.3	3.6	4.3	39.3	4.5	18.1	19.9	3.3	4.2	7.7	9.3	10.8	10.2	7.3	7.9	16.8	5.9	11.0	11.3
PTS	PTPS	ENSG00000150787	"6-pyruvoyltetrahydropterin synthase"	Q03393	11	112226365-112269955	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Tetrahydrobiopterin biosynthesis"	Lyase	"Disease mutation, Phenylketonuria"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA001481	Uncertain		Approved	Cytosol				Cytosol		"HPA001481: AB_1079716"	"unprognostic (2.08e-2)"	"unprognostic (1.91e-1)"	"unprognostic (9.66e-3)"	"unprognostic (8.38e-3)"	"unprognostic (4.58e-1)"	"unprognostic (3.28e-3)"	"unprognostic (2.38e-2)"	"unprognostic (1.81e-2)"	"unprognostic (2.05e-2)"	"unprognostic (8.74e-2)"	"unprognostic (2.59e-1)"	"unprognostic (7.07e-2)"	"unprognostic (3.81e-2)"	"unprognostic (1.20e-2)"	"unprognostic (2.97e-1)"	"unprognostic (1.52e-3)"	"unprognostic (1.65e-1)"	6.7	37.1	13.9	6.3	16.6	12.2	13.9	8.9	16.5	10.4	12.7	10.2	6.1	10.7	9.3	20.3	17.9	8.2	14.7	11.6	11.8	28.9	21.9	40.7	5.6	10.4	23.5	14.3	6.7	11.9	12.1	21.5	12.1	18.8	14.9	14.4	9.9	10.9	11.4	11.7	11.5	10.9	12.4	16.8	5.1	18.8	6.7	9.8	3.6	16.3	13.2	7.7	9.3	16.1	6.3	6.8	1.9	5.5	3.4	5.9	2.9	10.7	11.3	12.4	5.3	8.9	10.6	16.4	32.0	14.6	17.6	18.7	25.5	10.8	11.4	24.5	18.8	15.6	17.5	20.6	19.0	9.3	14.7	2.9	17.5	20.9	28.1	7.0	1.6	18.4	29.2	16.8	19.9	13.1	11.0	6.2	11.0	11.8	5.4	9.2	9.2	22.4	3.6	2.4	16.4	37.8	15.4	14.0	14.1	18.0	17.6	10.0	13.2	6.3	16.6	17.3	18.9	20.6	25.2	4.3	8.6	27.4	12.0	7.5	18.0	0.9	2.1	1.9	3.8	2.3	3.8	5.5	5.0	4.7	3.6	6.3	3.5	4.5	1.0	3.4	5.5	6.8	5.9	2.9	13.9	16.6	8.9	16.5	11.8	28.9	23.5	14.3	18.8	9.8
RPS3	"FLJ26283, FLJ27450, MGC87870, S3"	ENSG00000149273	"Ribosomal protein S3"	P23396	11	75399486-75422280	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins"	"Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation"	"DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA063339	Uncertain		Supported	"Endoplasmic reticulum,Cytosol"			430000	"Endoplasmic reticulum, Cytosol"		"HPA063339: "	"unprognostic (3.62e-2)"	"unprognostic (6.94e-3)"	"unprognostic (2.64e-1)"	"unprognostic (1.44e-2)"	"unprognostic (5.55e-2)"	"unprognostic (1.08e-2)"	"unprognostic (1.22e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.69e-1)"	"unprognostic (5.75e-2)"	"unprognostic (3.27e-3)"	"unprognostic (1.96e-1)"	"prognostic unfavourable (6.92e-6)"	"unprognostic (3.22e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.89e-2)"	"unprognostic (2.19e-1)"	72.2	52.7	36.6	108.4	41.2	122.2	136.6	32.1	33.8	105.1	102.0	32.5	65.2	65.8	102.4	84.7	136.5	92.2	107.7	58.5	29.7	26.5	52.9	78.1	71.0	218.6	47.6	30.6	224.7	288.7	13.8	51.3	75.9	35.0	105.7	65.7	47.6	151.0	61.8	86.9	117.6	78.0	110.6	42.1	121.4	75.4	54.1	36.5	126.5	119.4	134.7	130.1	110.3	118.9	104.5	69.7	22.6	44.5	64.6	144.2	213.9	85.5	53.1	75.5	83.1	95.5	170.4	97.7	82.1	105.8	109.0	71.1	153.1	102.5	299.4	100.6	73.7	124.1	97.4	152.7	100.5	79.2	76.1	122.6	53.0	67.6	142.6	197.9	80.4	199.9	208.7	74.5	207.1	142.9	122.1	85.3	97.9	94.0	118.7	95.2	94.8	63.0	112.8	264.9	218.1	107.0	71.6	65.0	92.2	60.5	143.9	83.5	146.9	151.7	114.4	52.7	87.8	71.8	74.1	78.3	96.5	331.7	31.6	111.1	53.2	22.6	44.5	14.7	94.2	31.6	129.1	104.5	123.0	99.4	69.7	95.6	144.2	111.8	11.2	64.6	30.1	60.8	78.2	213.9	36.6	41.2	32.1	33.8	29.7	26.5	47.6	30.6	35.0	36.5
SCLY	SCL	ENSG00000132330	"Selenocysteine lyase"	Q96I15	2	238060889-238099413	"Enzymes, Predicted intracellular proteins"		"Lyase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA055760	Uncertain		Approved	"Golgi apparatus"			110000	"Golgi apparatus"		"HPA055760: "	"unprognostic (7.39e-3)"	"unprognostic (1.43e-1)"	"unprognostic (3.29e-2)"	"unprognostic (8.65e-5)"	"unprognostic (8.96e-2)"	"unprognostic (9.85e-3)"	"unprognostic (1.14e-3)"	"unprognostic (4.24e-2)"	"unprognostic (1.59e-2)"	"unprognostic (8.38e-2)"	"unprognostic (3.98e-3)"	"unprognostic (1.03e-2)"	"unprognostic (1.02e-3)"	"unprognostic (3.73e-1)"	"unprognostic (4.37e-2)"	"unprognostic (2.50e-3)"	"unprognostic (1.98e-1)"	4.1	3.8	6.0	6.3	7.4	5.3	3.6	10.2	7.4	4.3	6.3	11.1	5.7	9.8	8.4	8.3	4.5	4.6	5.4	6.5	7.3	6.8	9.9	24.1	4.0	6.5	9.6	4.7	6.3	22.7	5.2	5.1	2.6	6.6	5.0	4.3	6.4	4.5	5.6	5.1	2.8	9.6	5.1	9.4	5.6	3.9	15.3	6.1	8.9	8.1	6.3	5.3	4.6	4.0	5.0	5.7	6.9	5.6	4.2	8.1	4.3	5.7	9.8	6.2	16.6	5.1	3.4	12.6	5.9	2.9	6.2	7.6	6.4	4.7	9.6	1.7	3.4	8.4	24.4	12.4	5.9	10.9	21.9	11.1	13.1	22.0	9.5	9.2	9.6	3.8	6.2	11.6	13.4	11.5	19.3	2.8	6.3	8.6	9.1	17.0	20.1	8.1	10.7	12.0	9.5	5.9	2.0	7.1	15.2	6.4	10.3	10.4	3.3	13.6	5.0	9.4	6.1	12.5	12.4	6.8	6.2	4.8	5.8	18.7	7.4	2.0	5.3	6.9	4.7	4.3	3.7	5.0	5.7	8.1	5.7	3.5	4.3	4.2	0.9	4.2	5.6	1.2	5.3	4.3	6.0	7.4	10.2	7.4	7.3	6.8	9.6	4.7	6.6	6.1
SDS	SDH	ENSG00000135094	"Serine dehydratase"	P20132	12	113392445-113426301	"Enzymes, Plasma proteins, Predicted intracellular proteins"	Gluconeogenesis	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	21	"liver: 276.9"	"Cell line enhanced"	"Detected in some"		"HMC-1: 5.4;SK-BR-3: 3.3"	"Cancer enriched"	"Detected in all"	31	"liver cancer: 165.3"	"Low region specificity"	"Detected in many"			"Cell type enriched"	"Detected in some"	10	"myeloid DC: 12.8"	"Lineage enriched"	"Detected in single"	15	"dendritic cells: 12.8"	"Low region specificity"	"Detected in single"							HPA039230	Uncertain		Approved	Mitochondria,Cytosol				Cytosol	Mitochondria	"HPA039230: AB_10674281"	"unprognostic (1.31e-1)"	"prognostic favourable (5.24e-4)"	"unprognostic (6.37e-3)"	"unprognostic (6.94e-2)"	"unprognostic (9.19e-3)"	"unprognostic (2.65e-2)"	"unprognostic (2.35e-2)"	"unprognostic (8.85e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.55e-1)"	"unprognostic (4.89e-2)"	"unprognostic (3.20e-1)"	"unprognostic (4.08e-3)"	"unprognostic (2.12e-1)"	"unprognostic (2.07e-2)"	"unprognostic (4.35e-1)"	"unprognostic (2.99e-2)"	0.9	0.9	2.2	1.4	5.9	0.5	0.4	0.6	2.1	0.5	0.9	0.8	0.0	0.7	0.4	0.2	0.2	0.2	1.4	0.2	1.7	2.5	0.2	276.9	0.6	0.6	4.2	0.7	0.3	0.4	0.1	0.0	1.0	2.8	0.3	0.8	1.3	0.3	0.2	0.2	0.2	0.7	0.3	1.3	0.5	0.9	0.3	0.8	0.1	0.3	0.0	0.3	0.8	0.0	0.0	12.8	0.6	0.8	0.2	0.0	0.3	0.0	0.4	0.2	1.3	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.4	0.2	0.4	2.3	0.0	0.4	0.0	0.0	0.0	0.5	0.5	1.3	0.6	0.6	0.1	0.8	5.4	0.0	0.0	0.0	0.0	0.0	0.9	0.6	0.0	1.4	0.1	0.4	0.8	0.9	0.0	0.8	0.1	0.2	0.5	0.1	0.1	1.6	3.3	0.7	1.2	1.7	0.6	0.0	0.9	1.1	0.3	0.7	0.4	0.2	1.1	0.8	0.3	0.1	0.8	0.0	0.0	0.7	0.0	0.0	0.0	0.0	12.8	0.0	0.0	0.0	0.6	0.2	0.1	1.3	0.0	0.3	2.2	5.9	0.6	1.6	1.7	2.5	4.2	0.7	2.8	0.8
SDSL	"cSDH, SDS-RS1"	ENSG00000139410	"Serine dehydratase like"	Q96GA7	12	113422237-113438276	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 53.2"	"Cell line enhanced"	"Detected in many"		"HMC-1: 22.2;MCF7: 38.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	8	"classical monocyte: 6.5;intermediate monocyte: 7.1;myeloid DC: 13.2;plasmacytoid DC: 12.8"	"Group enriched"	"Detected in many"	8	"dendritic cells: 13.2;monocytes: 7.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			HPA005740	Approved		Approved	Cytosol				Cytosol		"HPA005740: AB_10601486"	"unprognostic (1.34e-1)"	"unprognostic (8.33e-2)"	"unprognostic (3.62e-2)"	"unprognostic (3.54e-2)"	"unprognostic (2.24e-2)"	"unprognostic (6.17e-3)"	"unprognostic (1.57e-1)"	"unprognostic (6.46e-2)"	"unprognostic (8.22e-2)"	"unprognostic (2.00e-2)"	"prognostic favourable (8.58e-4)"	"unprognostic (2.93e-1)"	"prognostic favourable (3.09e-5)"	"unprognostic (2.22e-2)"	"unprognostic (1.43e-1)"	"unprognostic (2.54e-1)"	"unprognostic (7.33e-2)"	3.1	15.3	4.2	3.8	5.1	1.4	2.8	1.5	7.1	2.6	7.1	5.5	6.2	10.0	2.5	9.7	1.3	4.6	5.2	7.2	3.6	6.1	15.5	53.2	2.8	2.8	9.5	4.2	4.6	15.3	5.0	7.6	3.1	7.8	4.2	5.0	4.6	4.9	4.5	2.1	0.7	7.8	2.9	8.8	3.0	5.2	7.0	2.6	1.5	20.3	1.3	1.6	4.0	1.5	1.1	13.2	0.3	7.1	1.3	0.2	1.7	3.5	14.0	1.9	5.8	0.4	0.8	1.4	2.0	0.5	2.2	1.8	5.9	3.8	0.1	10.5	3.3	3.6	0.9	4.7	0.7	8.4	3.5	9.0	3.4	2.5	11.8	1.1	22.2	1.9	6.7	5.4	8.0	3.2	6.9	2.7	2.6	38.0	0.0	4.5	2.0	6.0	0.0	2.9	6.7	5.7	4.4	0.6	0.2	8.6	9.8	8.3	12.0	10.2	2.9	2.7	5.2	11.9	1.8	0.6	0.5	0.1	11.4	3.7	3.3	0.1	6.5	0.0	0.0	7.1	0.0	1.1	0.0	0.0	13.2	0.1	0.0	0.0	0.3	1.3	0.9	12.8	0.2	1.7	4.2	5.1	1.5	7.1	3.6	6.1	9.5	4.2	7.8	2.6
SGPL1	SPL	ENSG00000166224	"Sphingosine-1-phosphate lyase 1"	O95470	10	70815961-70881173	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Lipid metabolism, Sphingolipid metabolism"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"RT4: 44.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021125, HPA023086"	Enhanced		Supported	"Endoplasmic reticulum"				"Endoplasmic reticulum"		"HPA021125: AB_1856803, HPA023086: AB_1856804"	"unprognostic (1.14e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.07e-2)"	"unprognostic (2.13e-1)"	"unprognostic (2.34e-1)"	"unprognostic (7.60e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.06e-1)"	"unprognostic (1.70e-2)"	"unprognostic (2.12e-1)"	"unprognostic (9.52e-2)"	"unprognostic (3.42e-1)"	"unprognostic (2.14e-1)"	"unprognostic (9.21e-2)"	"unprognostic (4.68e-3)"	9.6	11.2	12.0	20.2	11.4	4.9	24.4	10.8	10.6	16.2	17.1	16.0	21.9	13.3	15.5	16.8	26.7	13.5	13.4	8.3	11.3	9.8	18.2	27.1	10.4	20.1	11.9	9.5	10.0	34.6	15.4	10.2	11.3	10.4	16.1	15.6	7.6	15.0	19.5	7.6	28.6	32.5	12.1	15.7	22.9	10.3	15.3	11.0	14.7	17.6	12.8	18.0	21.4	26.8	5.6	9.7	8.9	24.8	10.9	11.5	6.6	10.5	14.1	13.6	15.5	3.7	4.9	9.0	6.2	6.7	6.8	8.9	15.3	23.4	9.5	7.4	6.3	17.8	11.7	12.5	9.7	15.2	6.2	0.9	7.2	18.2	14.2	4.1	8.6	9.2	21.2	9.1	24.0	4.2	2.8	8.3	9.6	11.7	5.0	2.8	6.1	7.8	6.5	10.4	3.5	10.8	44.8	9.3	11.3	12.4	19.1	11.3	9.9	3.0	8.1	6.1	16.2	4.7	11.9	3.4	4.7	4.4	6.1	7.7	4.3	0.6	11.5	7.9	11.5	20.3	10.4	4.7	7.5	9.4	9.7	5.6	5.7	9.0	8.9	10.9	24.8	5.4	6.8	6.6	12.0	11.4	10.8	10.4	11.3	9.8	11.9	9.5	10.4	11.0
SRR	"ILV1, ISO1"	ENSG00000167720	"Serine racemase"	Q9GZT4	17	2303383-2325260	"Enzymes, Predicted intracellular proteins"		"Allosteric enzyme, Isomerase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007529, CAB015343"	Approved		Approved	Vesicles				Vesicles		"CAB015343: AB_2195009, HPA007529: "	"unprognostic (2.96e-1)"	"unprognostic (7.86e-2)"	"unprognostic (6.01e-2)"	"prognostic favourable (6.20e-5)"	"unprognostic (3.05e-1)"	"unprognostic (1.57e-2)"	"unprognostic (4.32e-2)"	"unprognostic (9.97e-2)"	"unprognostic (9.09e-2)"	"unprognostic (4.85e-2)"	"prognostic favourable (8.16e-4)"	"unprognostic (5.17e-2)"	"prognostic favourable (2.45e-6)"	"unprognostic (6.14e-2)"	"unprognostic (1.99e-1)"	"unprognostic (1.89e-1)"	"unprognostic (5.84e-2)"	11.6	12.6	17.1	7.7	14.7	13.9	16.7	12.2	24.9	8.4	10.4	13.9	11.4	7.9	10.9	11.3	12.9	10.0	9.6	12.6	15.2	13.0	10.3	9.0	10.9	7.0	12.6	15.6	9.8	14.8	11.0	9.7	6.5	12.4	9.6	8.8	10.6	11.9	9.3	16.9	13.4	7.5	15.0	13.2	7.3	9.2	13.8	9.0	13.4	13.8	6.1	6.0	12.1	7.3	9.7	15.5	5.2	12.6	13.9	13.5	8.7	7.2	13.2	24.0	8.9	13.1	13.8	11.7	15.4	9.6	10.2	10.6	12.2	9.2	13.6	2.0	15.9	15.3	6.6	5.6	13.0	15.8	12.9	7.0	9.8	4.6	13.2	2.0	3.9	11.7	5.8	22.8	11.0	14.9	7.2	10.1	22.7	4.3	13.9	2.7	5.0	10.0	23.1	27.2	6.3	11.8	3.3	4.7	12.1	13.4	1.6	7.0	10.5	4.9	11.7	11.0	7.8	12.4	9.1	8.9	12.0	2.5	19.6	6.6	14.9	2.4	8.2	5.2	9.5	8.7	9.9	9.7	12.3	10.1	15.5	8.9	10.4	13.5	1.0	13.9	12.6	10.4	8.9	8.7	17.1	14.7	12.2	24.9	15.2	13.0	12.6	15.6	12.4	9.0
TGDS	"SDR2E1, TDPGD"	ENSG00000088451	"TDP-glucose 4,6-dehydratase"	O95455	13	94574051-94596257	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 41.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039927, HPA040857"	Approved		Approved	Nucleoplasm,Nucleoli,Cytosol				Nucleoplasm	"Nucleoli, Cytosol"	"HPA039927: AB_10795238, HPA040857: AB_10794867"	"unprognostic (4.07e-2)"	"unprognostic (3.56e-1)"	"unprognostic (2.66e-2)"	"unprognostic (2.76e-1)"	"unprognostic (1.27e-1)"	"unprognostic (2.25e-2)"	"unprognostic (1.60e-1)"	"unprognostic (2.87e-1)"	"unprognostic (9.99e-2)"	"unprognostic (1.96e-1)"	"unprognostic (9.17e-2)"	"prognostic unfavourable (2.48e-4)"	"unprognostic (5.51e-2)"	"unprognostic (1.13e-2)"	"unprognostic (2.26e-1)"	"unprognostic (1.71e-2)"	"unprognostic (1.09e-1)"	11.1	12.2	7.9	11.4	11.8	5.8	13.4	8.0	7.8	11.9	9.0	9.0	13.4	11.1	13.7	13.2	10.3	10.5	8.7	7.7	7.0	7.0	11.8	31.9	7.8	12.5	11.8	6.8	13.9	14.1	6.2	24.3	10.8	10.1	10.5	10.6	15.4	12.5	12.7	7.6	7.9	11.1	10.3	12.6	11.9	9.8	7.2	12.6	27.1	15.8	8.9	12.5	10.9	9.2	9.9	8.0	10.5	7.0	10.4	17.4	6.7	7.2	3.0	5.1	4.6	7.6	6.1	6.4	6.6	6.4	6.3	6.1	8.4	7.1	11.2	6.7	4.6	4.6	9.0	5.2	6.5	8.9	3.6	9.0	3.6	7.8	9.6	30.8	6.2	7.1	4.2	3.5	10.1	5.8	8.8	3.9	5.6	4.4	8.4	15.9	6.7	3.9	7.2	5.2	6.6	7.9	3.2	7.3	4.0	5.0	10.5	18.6	4.7	16.7	5.3	2.5	6.6	3.9	5.5	8.9	4.8	41.2	6.9	11.4	6.8	10.5	5.3	9.6	9.6	6.2	14.5	9.9	11.3	10.5	8.0	7.3	17.4	12.4	1.5	10.4	7.0	7.1	12.5	6.7	7.9	11.8	8.0	7.8	7.0	7.0	11.8	6.8	10.1	12.6
TKFC	"DAK, DKFZP586B1621, NET45"	ENSG00000149476	"Triokinase and FMN cyclase"	Q3LXA3	11	61333210-61353295	"Enzymes, Predicted intracellular proteins"		"Kinase, Lyase, Multifunctional enzyme, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 90.2;liver: 42.8"	"Cell line enhanced"	"Detected in all"		"Hep G2: 39.8;RPMI-8226: 42.0;T-47d: 42.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039486, HPA048186"	Enhanced		Approved	Nucleoplasm,Cytosol			4800000	"Nucleoplasm, Cytosol"		"HPA039486: AB_10795402, HPA048186: AB_2680305"	"unprognostic (4.00e-1)"	"unprognostic (3.13e-1)"	"unprognostic (7.42e-2)"	"prognostic favourable (1.32e-5)"	"unprognostic (1.07e-1)"	"unprognostic (1.19e-1)"	"unprognostic (3.02e-2)"	"unprognostic (2.81e-3)"	"unprognostic (1.49e-1)"	"unprognostic (2.47e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.15e-1)"	"prognostic favourable (8.38e-5)"	"unprognostic (2.07e-2)"	"unprognostic (8.96e-2)"	"unprognostic (3.30e-1)"	"unprognostic (4.02e-1)"	3.1	34.7	3.6	6.1	5.3	5.3	4.6	3.7	7.3	3.4	43.4	7.6	8.0	69.5	4.6	7.8	6.2	5.9	8.8	2.8	3.1	2.6	17.4	42.8	3.5	5.2	3.3	5.3	4.5	9.8	3.0	5.5	3.9	4.4	5.0	2.3	7.3	7.2	7.1	4.6	6.1	90.2	2.6	3.1	5.4	5.7	17.1	3.4	5.5	6.4	6.3	6.7	5.4	3.9	9.7	18.4	5.4	11.4	5.3	10.9	7.8	6.0	15.3	2.7	9.3	3.4	3.7	7.6	3.5	3.8	3.3	2.1	6.9	14.6	7.5	12.4	2.5	8.5	5.0	6.6	1.1	12.9	6.7	4.6	8.1	39.8	5.8	3.9	7.8	5.8	4.5	3.1	11.0	3.3	8.1	14.5	2.4	27.4	3.4	3.6	7.4	10.5	6.1	4.2	42.0	5.3	10.7	10.4	9.3	6.5	11.4	5.9	42.0	2.8	3.9	6.6	6.9	5.2	2.1	26.9	22.2	6.7	6.8	3.6	6.0	2.3	11.4	5.4	6.7	6.8	8.6	9.7	7.8	6.5	18.4	9.7	5.6	5.9	0.9	5.3	5.3	9.0	10.9	7.8	3.6	5.3	3.7	7.3	3.1	2.6	3.3	5.3	4.4	3.4
TSEN2	"MGC2776, SEN2, SEN2L"	ENSG00000154743	"TRNA splicing endonuclease subunit 2"	Q8NCE0	3	12484432-12539623	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"mRNA processing, tRNA processing"	Lyase	"Neurodegeneration, Pontocerebellar hypoplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027120, HPA027125, HPA027268"	Approved		Supported	Nucleoplasm,Centrosome,Cytosol				Nucleoplasm	"Centrosome, Cytosol"	"HPA027120: AB_10600197, HPA027125: AB_10601896, HPA027268: AB_10601347"	"unprognostic (5.58e-2)"	"unprognostic (4.49e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.71e-2)"	"unprognostic (9.59e-2)"	"unprognostic (1.13e-1)"	"prognostic unfavourable (1.13e-5)"	"unprognostic (1.42e-1)"	"unprognostic (5.66e-2)"	"unprognostic (1.28e-1)"	"unprognostic (2.71e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.41e-2)"	"unprognostic (6.99e-2)"	"unprognostic (4.90e-2)"	"unprognostic (6.06e-2)"	"prognostic favourable (3.49e-4)"	8.8	10.6	9.7	8.8	19.1	6.7	10.9	16.5	14.0	10.4	9.8	12.7	8.4	5.8	14.0	9.9	7.9	12.8	10.3	14.3	10.5	12.3	9.8	7.3	7.3	10.9	11.5	7.6	18.0	11.9	14.3	15.3	4.9	10.2	10.5	10.9	13.5	7.2	13.1	16.7	15.3	6.1	12.3	12.3	6.1	8.5	11.3	9.1	9.9	12.5	9.6	8.1	8.6	8.3	8.5	7.1	2.6	4.2	5.0	13.7	5.6	8.0	14.0	7.5	9.9	12.8	13.6	17.4	7.6	6.7	8.1	5.9	7.9	8.6	9.7	5.3	6.2	7.5	12.5	13.0	9.3	7.6	15.6	10.6	18.8	8.1	9.9	16.6	4.1	11.7	15.1	14.8	18.2	6.5	15.6	5.3	9.4	15.1	12.6	7.6	10.6	16.9	9.6	5.2	19.3	12.2	8.2	4.9	8.6	7.0	6.3	5.9	11.4	11.6	5.8	5.2	5.1	7.1	11.7	5.0	12.7	12.0	7.0	16.7	6.5	2.4	4.2	0.3	6.4	4.2	10.9	8.5	9.8	7.4	5.9	8.3	13.7	11.7	2.6	5.0	3.6	7.1	3.5	5.6	9.7	19.1	16.5	14.0	10.5	12.3	11.5	7.6	10.2	9.1
TSEN34	"LENG5, SEN34, SEN34L"	ENSG00000170892	"TRNA splicing endonuclease subunit 34"	Q9BSV6	19	54189938-54194536	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"mRNA processing, tRNA processing"	Lyase	"Disease mutation, Neurodegeneration, Pontocerebellar hypoplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"neutrophil: 24.8"	"Group enriched"	"Detected in many"	6	"granulocytes: 24.8;monocytes: 8.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041111, HPA048208"	Approved		Supported	Nucleoplasm				Nucleoplasm		"HPA041111: AB_10794263, HPA048208: "	"unprognostic (3.24e-2)"	"unprognostic (2.95e-2)"	"unprognostic (1.59e-1)"	"unprognostic (3.88e-2)"	"unprognostic (3.48e-2)"	"unprognostic (4.82e-2)"	"prognostic unfavourable (1.44e-7)"	"unprognostic (2.38e-1)"	"unprognostic (7.35e-2)"	"unprognostic (1.51e-1)"	"unprognostic (5.04e-3)"	"unprognostic (8.98e-2)"	"unprognostic (4.55e-3)"	"unprognostic (2.02e-3)"	"unprognostic (1.81e-1)"	"unprognostic (2.81e-1)"	"unprognostic (1.12e-1)"	12.3	28.0	10.4	10.8	10.2	8.2	15.4	4.0	12.8	19.8	19.5	9.4	19.2	3.0	17.3	23.4	20.2	25.3	18.1	20.0	8.8	9.8	15.4	20.0	13.4	18.2	8.7	8.9	31.8	27.3	19.2	14.3	22.0	8.7	23.2	12.3	15.7	17.8	29.5	15.7	14.7	9.8	18.6	7.8	18.0	13.0	27.3	7.7	12.9	28.5	19.6	14.9	19.8	15.5	1.4	2.6	24.8	8.1	0.8	2.4	1.5	28.9	4.2	11.8	16.8	7.0	14.3	12.8	3.6	7.3	8.8	8.2	2.1	4.2	2.2	1.0	5.6	20.4	16.0	21.3	6.4	7.5	24.4	2.6	0.8	2.3	6.7	0.7	3.6	22.9	9.8	6.0	7.1	17.9	5.8	1.3	18.6	3.5	1.5	0.0	2.7	3.1	7.3	8.0	1.0	25.2	2.5	0.6	6.8	0.8	21.6	8.0	17.1	2.1	1.2	0.0	12.2	12.6	22.2	8.2	7.9	2.0	21.1	1.3	13.4	4.1	8.1	17.8	0.9	3.3	1.8	1.0	1.3	2.4	2.3	1.4	2.3	0.9	24.8	0.8	5.2	2.6	0.7	1.5	10.4	10.2	4.0	12.8	8.8	9.8	8.7	8.9	8.7	7.7
TYW1	"FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W"	ENSG00000198874	"TRNA-yW synthesizing protein 1 homolog"	Q9NV66	7	66995173-67239519	"Enzymes, Predicted membrane proteins"	"tRNA processing"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097"	Approved		Approved	Nucleoplasm,Nucleoli				"Nucleoplasm, Nucleoli"		"HPA013568: , HPA014118: , HPA015535: AB_1856487, HPA043136: , HPA047029: , HPA047052: , HPA052097: "	"unprognostic (1.53e-1)"	"unprognostic (5.49e-3)"	"unprognostic (1.62e-1)"	"unprognostic (3.05e-2)"	"unprognostic (1.84e-2)"	"unprognostic (2.20e-1)"	"unprognostic (1.83e-2)"	"unprognostic (1.79e-1)"	"unprognostic (1.47e-1)"	"prognostic unfavourable (1.73e-4)"	"unprognostic (4.86e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.85e-2)"	"unprognostic (4.70e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.79e-2)"	15.4	19.1	10.2	12.3	15.4	11.9	15.1	14.9	15.3	18.8	12.9	21.2	18.2	14.1	22.7	15.3	12.0	15.5	10.8	12.9	10.8	9.8	15.2	17.7	11.1	15.5	14.1	10.8	19.4	23.9	22.9	28.0	13.2	14.5	14.9	16.5	17.8	15.3	14.7	26.2	14.4	12.8	14.0	13.9	15.1	12.6	13.7	13.4	19.7	19.0	13.6	23.3	15.3	15.2	9.6	8.3	3.6	9.1	11.2	11.8	5.3	10.5	13.5	8.3	17.1	12.4	8.6	9.6	11.3	8.6	9.0	8.4	15.4	13.8	18.4	17.4	10.4	12.5	17.1	13.9	13.0	14.4	13.1	7.9	11.2	10.4	12.3	18.3	10.6	8.8	14.1	12.1	18.7	8.1	20.9	11.1	10.2	10.4	11.5	15.3	14.5	12.1	13.1	11.6	23.1	12.2	10.7	12.7	12.6	13.6	26.4	11.3	18.0	13.0	9.5	10.3	7.4	8.2	15.4	11.2	15.8	22.2	8.4	17.2	14.2	2.0	7.0	3.6	8.6	7.8	11.7	8.5	9.4	9.8	8.3	9.6	11.5	11.8	2.0	11.2	9.1	6.6	6.8	5.3	10.2	15.4	14.9	15.3	10.8	9.8	14.1	10.8	14.5	13.4
UMPS		ENSG00000114491	"Uridine monophosphate synthetase"	P11172	3	124730366-124749273	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Pyrimidine biosynthesis"	"Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036178, HPA036179"	Uncertain		Supported	Cytosol				Cytosol		"HPA036178: AB_10673002, HPA036179: AB_10673615"	"unprognostic (6.41e-2)"	"unprognostic (6.70e-2)"	"unprognostic (1.79e-2)"	"unprognostic (1.13e-3)"	"unprognostic (2.70e-1)"	"unprognostic (1.72e-1)"	"unprognostic (1.15e-3)"	"unprognostic (5.51e-2)"	"unprognostic (4.85e-3)"	"unprognostic (1.43e-1)"	"unprognostic (5.36e-2)"	"prognostic unfavourable (9.20e-4)"	"unprognostic (2.18e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.91e-1)"	"unprognostic (4.61e-2)"	"unprognostic (1.31e-1)"	8.4	12.2	4.9	6.8	6.8	4.8	8.0	9.3	7.6	5.9	9.1	8.5	5.2	8.4	6.8	6.7	13.2	8.2	6.6	3.6	4.0	3.9	9.6	20.7	5.2	10.1	7.3	3.6	8.9	19.0	9.5	9.3	11.6	4.7	6.4	7.1	6.4	8.9	4.0	10.9	9.5	8.5	5.5	5.9	9.8	8.3	6.8	6.2	10.6	7.4	12.0	9.3	7.8	6.4	16.6	13.1	4.6	9.8	10.2	13.0	7.9	1.4	4.3	5.0	2.0	3.0	3.4	5.2	7.4	2.3	3.1	2.6	3.7	2.0	3.8	8.2	2.9	8.3	7.0	2.4	5.0	4.3	4.0	7.7	2.8	2.6	2.6	8.0	5.9	3.8	2.3	1.9	3.9	1.4	3.5	1.8	2.3	3.3	9.9	1.5	10.9	2.8	6.5	5.9	3.1	2.5	2.4	4.0	2.6	11.1	4.0	4.1	4.0	3.0	14.2	2.5	5.0	6.8	2.9	7.4	10.1	10.3	2.8	3.3	2.5	4.5	9.0	4.6	12.5	9.8	12.1	13.7	8.9	11.3	13.1	16.6	13.0	10.4	0.6	10.2	8.0	9.7	10.3	7.9	4.9	6.8	9.3	5.7	4.0	3.9	7.3	3.6	4.7	6.2
URAD	PRHOXNB	ENSG00000183463	"Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase"	A6NGE7	13	27977714-27988654	"Enzymes, Predicted intracellular proteins"	"Purine metabolism"	"Decarboxylase, Lyase"		"Evidence at transcript level"	"Evidence at transcript level"				"Group enriched"	"Detected in some"	5	"breast: 8.8;intestine: 16.7"	"Group enriched"	"Detected in some"	13	"BEWO: 6.7;CACO-2: 6.1"	"Cancer enriched"	"Detected in some"	15	"colorectal cancer: 7.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA038972	Uncertain									"HPA038972: AB_10671869"			"unprognostic (2.00e-1)"											"unprognostic (1.05e-1)"	"unprognostic (5.21e-2)"			2.8	0.0	0.1	1.5	0.1	0.0	8.8	0.6	0.1	0.1	16.7	0.1	0.1	8.2	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.1	0.9	0.1	0.1	0.1	0.1	0.0	16.0	0.2	0.1	0.1	0.0	0.2	0.1	0.6	0.1	0.1	0.1	0.1	0.1	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.7	0.0	0.0	0.0	0.0	6.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.6	0.1	0.1	0.0	0.1	0.1	0.1	0.1
UROC1	"FLJ31300, HMFN0320"	ENSG00000159650	"Urocanate hydratase 1"	Q96N76	3	126481281-126517773	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Histidine metabolism"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	32	"liver: 50.7"	"Cell line enriched"	"Detected in some"	8	"NB-4: 9.3"	"Cancer enriched"	"Detected in single"	100	"liver cancer: 12.1"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in single"		"neutrophil: 1.5"	"Lineage enhanced"	"Detected in single"		"granulocytes: 1.5"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA069863	Enhanced						510000			"HPA069863: "	"unprognostic (1.28e-1)"	"unprognostic (2.74e-2)"	"unprognostic (1.08e-1)"	"unprognostic (7.43e-2)"	"unprognostic (6.43e-2)"	"unprognostic (1.43e-1)"	"unprognostic (2.23e-3)"	"unprognostic (2.95e-1)"	"unprognostic (2.57e-2)"	"unprognostic (7.71e-2)"	"unprognostic (9.97e-2)"	"unprognostic (3.04e-1)"	"unprognostic (3.65e-5)"	"unprognostic (3.97e-2)"	"unprognostic (2.66e-1)"		"unprognostic (5.52e-2)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	50.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	9.3	0.0	0.0	0.1	0.0	0.4	0.0	0.0	0.5	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
UROD		ENSG00000126088	"Uroporphyrinogen decarboxylase"	P06132	1	45012147-45015575	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	"Decarboxylase, Lyase"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"K-562: 79.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027468, HPA028668, HPA030350"	Uncertain		Supported	Nucleoplasm,Cytosol			5200000	"Nucleoplasm, Cytosol"		"HPA027468: AB_1858654, HPA028668: AB_10603458, HPA030350: "	"unprognostic (5.90e-2)"	"unprognostic (2.94e-2)"	"unprognostic (2.49e-1)"	"unprognostic (9.61e-2)"	"unprognostic (7.94e-2)"	"unprognostic (1.96e-1)"	"prognostic unfavourable (2.48e-4)"	"unprognostic (2.31e-2)"	"unprognostic (4.76e-2)"	"unprognostic (6.75e-2)"	"unprognostic (7.72e-3)"	"unprognostic (3.92e-1)"	"unprognostic (1.24e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.41e-1)"	"unprognostic (8.73e-2)"	"unprognostic (8.12e-2)"	20.7	50.2	23.1	12.2	26.2	67.5	20.7	14.2	28.6	17.7	24.2	16.5	25.9	11.2	27.8	22.6	17.8	20.8	17.4	34.0	21.1	20.3	29.6	58.1	14.3	14.8	21.6	22.9	27.4	18.4	35.9	17.6	25.8	16.2	19.2	12.3	24.3	45.6	19.2	28.8	12.1	13.2	22.9	18.9	16.6	15.0	16.3	11.5	17.2	26.3	23.6	16.0	15.0	13.0	25.7	48.6	20.6	36.3	26.0	27.4	35.6	12.5	8.2	13.2	17.3	22.8	21.5	6.4	15.3	39.6	32.3	24.9	11.8	6.6	8.9	16.2	23.2	6.5	25.1	29.9	22.5	7.9	26.4	46.0	19.0	39.1	26.6	14.0	8.6	22.3	19.0	30.8	25.0	41.4	79.8	9.8	30.8	10.5	9.5	12.1	20.5	29.1	14.4	19.6	12.9	28.1	10.6	14.1	11.1	16.8	12.6	25.9	9.9	14.7	26.8	18.4	14.4	6.3	24.7	10.2	10.9	7.5	28.8	21.3	9.2	17.6	36.3	20.6	19.7	25.8	20.0	25.7	23.8	19.2	48.6	23.7	22.3	20.3	6.6	26.0	15.5	32.4	27.4	35.6	23.1	26.2	14.2	28.6	21.1	20.3	21.6	22.9	16.2	11.5
UROS		ENSG00000188690	"Uroporphyrinogen III synthase"	P10746	10	125784980-125823248	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Lyase	"Disease mutation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044038	Approved		Approved	Nucleoplasm,Cytosol			15000	Nucleoplasm	Cytosol	"HPA044038: AB_10966692"	"unprognostic (8.86e-2)"	"unprognostic (7.64e-2)"	"unprognostic (2.77e-1)"	"unprognostic (7.19e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.41e-1)"	"unprognostic (1.08e-1)"	"unprognostic (5.82e-2)"	"unprognostic (1.27e-1)"	"unprognostic (4.35e-3)"	"unprognostic (4.23e-3)"	"unprognostic (2.00e-2)"	"prognostic unfavourable (6.27e-4)"	"unprognostic (1.58e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.68e-1)"	"unprognostic (3.93e-1)"	13.8	16.1	48.6	9.0	46.6	33.2	13.9	12.8	35.3	8.9	11.4	15.7	12.8	13.2	9.3	41.2	10.5	11.3	11.5	31.4	36.9	20.4	22.6	25.5	10.0	16.8	22.7	23.4	14.5	14.1	14.4	12.0	7.9	20.0	12.9	12.4	14.0	18.1	14.0	45.6	9.8	12.0	13.0	12.5	11.7	12.5	13.8	13.8	10.8	16.4	14.4	12.7	9.4	6.3	17.3	27.1	2.4	15.6	24.7	21.3	17.8	17.4	18.9	13.8	30.7	18.5	18.8	18.6	22.6	39.1	15.9	15.9	8.2	21.3	24.4	10.6	28.0	10.0	8.0	16.1	15.0	30.1	15.2	51.8	10.7	13.5	26.1	21.8	12.2	23.5	9.2	11.1	29.8	14.5	8.9	23.2	26.5	20.8	19.1	24.6	15.0	19.8	13.5	15.3	14.5	20.8	10.9	10.8	18.6	22.6	17.4	30.7	15.6	20.8	14.4	21.1	7.9	16.2	19.1	21.4	15.5	16.6	29.4	8.9	10.0	2.4	15.6	2.2	16.1	15.4	18.5	15.7	16.0	20.4	27.1	17.3	21.3	16.3	1.2	24.7	14.6	12.9	14.2	17.8	48.6	46.6	12.8	35.3	36.9	20.4	22.7	23.4	20.0	13.8
UXS1	"FLJ23591, SDR6E1, UGD"	ENSG00000115652	"UDP-glucuronate decarboxylase 1"	Q8NBZ7	2	106093303-106194339	"Enzymes, Predicted intracellular proteins"		"Decarboxylase, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPTEC TERT1: 82.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008825	Uncertain				"Intracellular and membrane"		10000			"HPA008825: AB_1858708"	"unprognostic (4.08e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.99e-1)"	"unprognostic (3.63e-2)"	"unprognostic (3.92e-2)"	"prognostic unfavourable (5.45e-4)"	"prognostic unfavourable (1.38e-4)"	"unprognostic (3.20e-3)"	"unprognostic (2.07e-1)"	"prognostic favourable (7.94e-4)"	"unprognostic (3.95e-2)"	"unprognostic (1.40e-2)"	"unprognostic (8.46e-2)"	"unprognostic (3.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (1.86e-2)"	"unprognostic (5.32e-2)"	12.3	11.7	15.2	17.3	19.9	20.7	20.1	23.0	20.5	14.1	13.3	11.9	27.6	9.5	16.1	22.3	15.6	19.2	16.2	20.0	17.0	18.2	40.2	16.1	28.8	20.7	15.1	11.6	16.3	17.0	18.6	13.4	37.9	19.6	16.2	15.6	14.7	11.6	17.6	18.0	11.5	9.9	13.8	22.9	19.7	17.9	19.4	10.6	15.0	26.2	14.1	19.1	21.6	15.3	11.6	7.5	11.2	9.8	11.9	34.1	15.1	16.2	12.4	13.0	9.8	23.3	17.4	28.2	18.0	17.0	12.8	16.0	24.2	27.9	3.0	22.5	18.7	8.2	5.7	14.8	14.0	15.7	9.9	9.0	5.5	27.1	9.2	7.3	10.0	11.2	16.3	13.0	8.8	13.4	5.2	7.2	26.4	11.6	8.1	15.6	15.3	16.6	15.1	9.8	8.4	82.7	15.4	4.3	4.8	12.9	11.7	10.7	4.4	23.3	12.0	14.4	15.1	11.6	11.1	8.9	12.2	4.1	14.3	16.4	26.4	3.9	9.8	11.2	8.8	8.0	9.5	4.9	19.6	14.3	7.5	11.6	25.4	17.6	2.0	11.9	5.3	5.4	34.1	15.1	15.2	19.9	23.0	20.5	17.0	18.2	15.1	11.6	19.6	10.6