Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" A3GALT2 "A3GALT2P, IGB3S, IGBS3S" ENSG00000184389 "Alpha 1,3-galactosyltransferase 2" U3KPV4 1 33306766-33321098 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "HeLa: 5.1;SiHa: 3.2" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 15 "granulocytes: 2.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "unprognostic (1.86e-2)" "unprognostic (2.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.61e-3)" "unprognostic (4.96e-2)" "unprognostic (6.83e-2)" "unprognostic (5.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" "unprognostic (4.90e-8)" "unprognostic (1.17e-1)" "unprognostic (1.12e-2)" "unprognostic (7.87e-2)" 0.7 0.1 0.1 1.2 0.2 1.3 0.4 1.3 0.9 0.4 0.2 0.0 0.5 0.0 0.2 0.2 1.4 0.1 0.2 0.1 0.4 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.4 0.1 0.6 0.0 0.2 0.4 0.2 0.1 0.1 0.2 0.2 0.8 0.3 2.1 0.4 0.0 0.2 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 5.1 0.0 0.2 0.0 0.0 0.7 0.2 0.2 0.6 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692112-42721298 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 21.5;ASC TERT1: 17.6;TIME: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "NK-cell: 1.4;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;NK-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001141 Uncertain Mitochondria Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favourable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 22.7 5.9 3.5 8.2 3.7 3.8 15.3 1.4 3.8 21.2 12.0 2.3 32.6 4.8 13.0 16.9 15.0 11.7 11.0 26.8 2.3 1.3 30.0 4.4 14.0 6.4 2.9 3.0 11.8 3.4 1.4 7.7 12.6 2.9 15.4 2.1 9.9 15.4 39.8 12.5 8.7 7.0 18.6 5.3 11.4 11.3 6.7 2.4 1.3 10.7 13.0 10.1 16.1 25.6 0.1 3.4 0.0 0.0 1.4 0.0 0.0 0.6 7.3 0.0 0.0 21.5 17.6 11.0 2.9 3.1 0.6 1.1 2.3 1.2 7.1 5.1 5.1 0.7 7.0 3.4 0.1 0.0 1.4 0.1 11.5 0.2 6.5 0.0 0.5 10.3 1.0 3.0 0.5 2.5 0.0 0.0 2.7 10.0 0.0 0.0 0.9 1.8 0.0 1.6 0.7 14.5 12.5 0.1 0.0 8.9 0.2 0.0 5.7 0.8 15.4 0.0 1.4 13.1 3.8 1.5 6.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 3.5 3.7 1.4 3.8 2.3 1.3 2.9 3.0 2.9 2.4 AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 56.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favourable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.0 3.1 9.2 2.2 9.0 0.9 4.7 0.8 10.8 8.3 4.7 10.3 2.9 1.9 9.7 5.8 2.8 5.7 3.9 2.8 7.2 6.4 6.3 56.5 4.7 1.1 8.2 8.0 4.7 4.6 7.6 8.9 2.2 6.0 13.3 5.0 6.6 1.7 5.4 3.6 1.8 2.0 7.0 7.0 2.0 3.2 7.2 9.2 0.9 7.0 1.2 1.3 5.5 4.9 0.4 0.4 0.0 0.7 0.0 0.7 0.0 2.1 5.4 16.4 0.0 3.2 12.8 5.9 5.6 2.7 3.2 3.3 5.2 0.6 0.0 0.9 6.2 1.9 7.3 2.6 2.3 0.0 6.3 0.0 6.1 8.8 2.6 0.0 2.4 5.2 1.6 2.6 3.4 3.0 0.9 0.1 12.3 5.5 2.6 0.1 12.4 4.9 0.0 5.1 0.0 2.9 9.8 13.2 15.5 4.4 1.1 5.4 0.0 1.0 2.0 8.3 8.9 9.3 8.7 0.0 0.0 0.0 8.3 0.0 9.7 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.3 0.3 0.4 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 9.2 9.0 0.8 10.8 7.2 6.4 8.2 8.0 6.0 9.2 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 109.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavourable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 5.1 5.9 11.0 5.7 11.9 7.8 6.9 25.2 26.5 4.8 4.2 3.9 6.3 3.8 4.7 7.1 3.8 4.9 4.3 7.9 14.4 12.8 7.2 3.1 7.5 6.8 9.4 11.6 3.3 6.7 109.7 10.3 6.9 10.2 5.0 4.6 4.7 3.6 12.3 6.8 3.7 3.7 5.4 9.3 5.5 5.4 4.1 6.9 4.7 16.0 2.1 5.3 4.9 5.8 1.0 0.8 4.1 3.9 2.8 5.6 1.3 16.5 9.9 9.1 8.8 8.7 9.7 29.3 13.5 10.7 8.2 7.2 10.0 6.6 0.5 3.3 17.5 7.7 7.0 7.0 16.7 12.3 2.9 9.0 6.0 6.8 7.9 6.3 21.4 8.3 6.2 15.4 19.9 17.3 1.9 9.3 14.2 2.8 5.8 3.3 4.4 5.5 3.9 9.9 1.4 6.4 34.7 3.0 4.8 7.8 6.0 7.0 3.5 8.9 17.2 18.3 12.3 13.1 13.2 9.2 2.4 1.0 15.3 10.7 12.5 2.5 1.4 0.6 4.5 0.6 4.2 0.4 4.0 3.0 0.8 1.0 5.6 4.5 4.1 2.8 3.9 0.7 3.1 1.3 11.0 11.9 25.2 26.5 14.4 12.8 9.4 11.6 10.2 6.9 AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 27.7;testis: 8.2" "Cell line enhanced" "Detected in some" "A549: 4.5;SCLC-21H: 5.6;U-266/70: 4.5;U-266/84: 4.7;U-698: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA054321 Supported Cytosol "Intracellular and membrane" Cytosol "HPA054321: " "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" 0.3 0.2 1.2 3.8 0.8 2.7 0.3 1.3 1.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.8 0.4 1.8 0.3 1.2 1.5 0.3 0.3 0.3 3.3 1.7 0.7 0.4 0.3 0.0 0.9 0.3 1.9 0.3 0.0 27.7 0.3 0.3 1.8 3.3 0.7 0.3 1.2 2.2 0.2 8.2 0.3 0.3 0.8 0.3 0.3 0.9 0.3 1.3 1.3 2.2 0.1 1.8 0.2 0.0 0.9 4.5 0.7 0.5 0.0 0.1 0.5 0.0 0.4 0.3 0.1 0.1 3.2 3.7 0.5 0.0 1.1 0.0 0.0 0.3 0.0 1.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.9 0.4 0.5 0.1 0.1 1.2 0.4 0.2 0.2 1.9 0.0 0.1 5.6 0.4 0.1 0.2 1.5 2.8 0.7 0.0 0.0 1.8 0.2 0.1 4.5 4.7 6.6 1.2 0.4 0.8 2.0 0.1 2.2 0.2 0.0 0.0 0.6 0.1 0.0 0.0 1.3 0.0 0.2 0.6 1.8 0.0 1.3 0.1 0.0 1.2 0.8 1.3 0.9 1.2 1.5 1.7 0.7 1.9 0.3 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81117295-81166077 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;intestine: 28.7" "Group enriched" "Detected in some" 6 "CACO-2: 29.6;SH-SY5Y: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "neutrophil: 3.6" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 2.8 4.7 14.3 3.2 16.6 3.7 0.9 19.0 29.0 1.2 3.3 16.5 0.0 28.7 1.0 1.1 1.7 1.2 2.7 2.3 23.6 13.9 1.2 1.2 9.7 1.5 20.1 13.6 1.0 17.9 3.6 6.4 2.6 11.0 2.4 1.1 4.1 5.6 3.6 1.1 1.9 20.3 1.3 35.3 5.9 4.5 1.3 9.8 0.0 1.3 0.0 1.0 1.3 1.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 29.6 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 1.6 1.1 1.4 1.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.1 0.0 0.1 0.5 0.1 1.3 2.4 0.2 0.0 0.0 2.8 10.2 0.2 0.0 1.4 0.3 0.8 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 14.3 16.6 19.0 22.3 23.6 13.9 20.1 13.6 11.0 9.8 ABAT GABAT ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674565-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 53.3;liver: 136.5;pancreas: 54.2" "Cell line enhanced" "Detected in many" "Hep G2: 44.3;MCF7: 28.5;RH-30: 25.1;T-47d: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria 1500000 Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favourable (5.36e-5)" "prognostic favourable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favourable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 2.1 12.6 26.1 2.7 39.3 1.7 3.2 19.9 43.3 2.2 5.2 10.9 0.1 17.5 2.1 5.0 3.0 2.8 2.7 6.2 20.4 30.9 53.3 136.5 2.8 2.8 24.5 26.1 5.3 54.2 4.0 22.1 2.3 14.3 9.9 4.2 2.6 2.6 2.5 1.4 2.1 8.4 2.1 14.1 2.5 3.9 6.3 11.8 1.0 12.7 0.4 3.3 6.4 1.1 2.2 1.9 8.8 5.8 1.6 2.5 1.8 0.2 0.0 11.8 6.7 1.9 0.6 0.5 1.4 0.8 0.7 0.2 4.4 0.3 1.4 0.5 0.8 3.0 0.7 2.8 0.9 0.8 0.6 1.9 0.0 44.3 3.1 0.4 3.0 2.5 1.2 1.2 0.5 0.2 0.3 1.0 0.2 28.5 0.7 0.2 1.0 0.1 3.4 25.1 0.6 0.4 7.0 1.9 5.7 0.6 0.4 0.0 15.6 1.2 0.2 0.2 2.0 0.9 0.0 1.1 0.1 0.3 0.3 2.0 1.4 1.1 3.1 4.1 2.5 3.6 1.1 0.8 1.7 1.7 1.9 2.2 1.1 1.8 8.8 1.6 5.8 0.3 1.6 1.8 26.1 39.3 19.9 35.1 20.4 30.9 24.5 26.1 14.3 11.8 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 70.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 26.1;classical monocyte: 7.6;neutrophil: 21.0" "Group enriched" "Detected in many" 5 "granulocytes: 26.1;monocytes: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Approved Vesicles Vesicles "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favourable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favourable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 26.5 10.5 5.2 7.4 12.2 32.2 70.3 8.5 10.3 7.6 10.2 10.5 5.9 7.4 4.6 4.0 22.7 3.7 10.4 9.8 7.4 4.5 10.1 18.4 14.1 8.7 18.5 4.6 4.2 12.8 9.1 8.6 20.2 14.9 5.8 6.7 4.4 21.1 7.4 10.4 24.8 15.1 8.1 19.0 7.0 8.9 8.1 12.5 3.3 13.2 9.9 6.7 11.2 16.0 1.7 3.6 26.1 7.6 0.9 2.4 2.5 8.3 2.9 3.5 3.7 14.9 5.7 7.3 34.2 13.6 9.4 7.1 4.6 2.9 7.0 4.7 10.7 2.8 5.5 8.3 9.6 25.3 5.4 17.8 11.4 3.1 7.4 4.0 5.8 6.3 28.9 15.8 13.5 15.7 10.6 5.3 20.9 4.5 2.9 2.8 9.5 9.6 1.2 10.2 4.0 12.2 16.7 4.4 5.9 15.0 8.1 3.5 8.7 3.5 8.7 8.3 6.6 15.4 14.8 4.8 13.3 3.3 8.9 7.4 6.4 26.1 7.6 4.4 1.2 3.7 1.0 1.7 0.9 1.4 3.6 1.2 0.8 1.3 21.0 0.9 2.7 0.9 2.4 2.5 5.2 12.2 8.5 10.3 7.4 4.5 18.5 4.6 14.9 12.5 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713946-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 20.1 11.6 12.4 15.0 18.1 10.7 22.0 6.7 16.0 28.9 34.3 29.1 12.1 11.9 26.6 16.9 21.4 20.8 30.9 14.2 10.3 8.4 9.9 6.7 13.8 8.7 24.1 9.4 24.2 12.2 27.7 14.5 13.6 17.1 27.3 15.8 19.4 14.6 18.0 10.8 14.2 17.0 66.6 14.3 10.8 21.9 9.8 21.2 5.8 19.5 11.4 9.1 35.8 31.9 3.1 3.1 1.1 5.0 2.4 2.6 1.6 7.0 15.7 16.9 20.4 24.8 30.3 6.2 12.4 19.5 14.6 12.4 12.3 9.2 11.6 7.2 16.5 13.7 8.5 11.5 10.8 7.3 5.3 7.6 26.9 10.5 16.9 11.7 10.7 22.1 12.7 26.1 16.2 20.2 42.6 9.3 17.8 13.4 14.8 9.6 18.7 11.6 17.2 21.9 12.6 14.7 8.3 15.8 19.7 20.8 8.1 10.0 15.9 10.8 23.1 56.0 14.5 21.4 19.5 2.8 6.6 15.6 23.1 9.7 17.7 0.2 2.1 1.1 2.0 1.2 2.6 3.1 2.0 1.9 2.0 1.4 1.9 1.7 0.2 2.4 5.0 3.1 0.9 1.6 12.4 18.1 6.7 16.0 10.3 8.4 24.1 9.4 17.1 21.2 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099327-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 31.7;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Supported Nucleoplasm Nucleoplasm "CAB017106: , HPA001866: AB_1078082, HPA072754: " "unprognostic (3.05e-1)" "prognostic unfavourable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavourable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavourable (8.40e-4)" 14.3 5.2 8.6 7.4 13.7 3.7 8.3 14.9 10.6 9.2 6.6 5.8 4.5 4.0 5.4 4.7 3.9 4.3 18.8 6.8 9.7 3.9 4.9 4.3 11.5 3.7 6.5 6.1 5.6 8.4 9.2 8.4 6.1 8.1 5.1 5.2 5.8 4.5 4.4 5.2 6.6 3.7 6.9 6.2 3.9 4.7 9.2 8.6 3.6 5.8 3.1 3.6 6.7 11.2 2.8 2.0 3.8 1.2 1.8 2.2 0.6 10.0 5.5 3.7 2.5 3.2 7.3 2.3 11.1 9.1 13.7 9.9 4.0 3.1 5.8 8.2 7.9 5.0 5.2 3.7 19.4 3.6 4.8 2.8 5.0 2.0 5.8 3.1 0.9 6.7 4.9 19.4 31.7 15.1 6.6 1.7 17.7 2.6 2.4 1.6 3.6 1.8 3.7 6.2 2.8 4.6 1.6 2.3 5.1 9.2 2.9 22.8 2.6 2.6 29.5 14.2 10.6 6.8 17.8 3.1 3.8 6.0 6.7 1.7 13.7 3.8 1.2 0.4 2.2 0.4 1.0 1.8 1.4 1.4 0.9 2.8 1.9 2.0 2.6 1.8 0.5 2.0 0.8 0.6 8.6 13.7 14.9 10.6 9.7 3.9 6.5 6.1 8.1 8.6 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Enhanced Peroxisomes 4300000 Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favourable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favourable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favourable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favourable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 9.5 12.7 11.0 5.6 11.9 9.6 10.2 8.1 14.3 6.7 16.1 12.5 10.6 23.4 4.9 13.3 12.1 4.6 16.0 17.7 10.2 8.9 48.7 152.1 8.2 5.9 14.0 9.4 5.0 19.2 7.4 5.9 6.8 11.0 13.4 12.4 7.3 11.5 9.4 9.8 6.2 23.8 4.8 12.7 10.0 8.5 4.4 10.9 5.7 9.3 10.1 10.2 9.4 7.0 9.2 47.0 32.8 45.2 17.8 19.3 18.8 8.4 9.2 3.1 9.9 13.6 7.9 10.9 7.8 11.3 8.9 8.5 12.3 9.5 5.0 5.6 12.4 5.6 8.5 13.1 4.9 7.3 8.8 6.5 8.1 34.8 8.8 14.8 14.5 14.7 9.4 7.6 5.5 12.0 6.0 5.9 9.9 11.0 14.3 10.6 3.3 11.2 3.3 6.0 8.4 25.1 25.1 2.7 4.2 7.6 85.3 5.4 8.8 11.9 8.7 5.4 5.2 10.7 10.6 7.8 5.0 3.9 8.8 12.9 8.5 15.3 29.9 32.8 13.6 40.7 11.4 9.2 13.1 13.3 47.0 8.7 13.0 12.1 20.4 17.8 45.2 27.7 19.3 18.8 11.0 11.9 8.1 14.3 10.2 8.9 14.0 9.4 11.0 10.9 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782167-49813960 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 245.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria 3200000 Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavourable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favourable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 22.7 12.9 9.4 6.9 10.7 4.4 13.0 3.6 7.0 4.1 27.2 8.0 7.8 25.9 5.1 5.1 7.1 4.1 9.2 38.9 6.8 7.0 60.3 245.7 7.9 7.5 10.7 6.1 6.4 13.6 6.3 7.1 7.5 6.7 7.9 18.4 9.5 3.3 6.2 22.9 4.2 37.0 11.3 9.7 6.9 6.0 6.5 7.5 8.4 15.7 8.8 5.0 8.1 4.9 13.0 31.8 27.5 33.0 35.5 40.9 28.6 0.7 13.9 23.2 21.2 30.7 16.2 11.8 7.1 11.6 12.0 9.3 29.5 12.0 12.4 15.2 26.1 0.9 38.6 4.5 11.9 37.9 9.1 8.8 18.1 34.9 14.5 0.1 16.6 21.4 1.5 19.4 6.1 19.6 7.6 11.7 33.2 16.0 0.5 19.1 21.0 5.6 30.4 49.6 45.4 40.5 0.6 33.3 26.4 0.5 16.3 1.1 9.2 12.8 9.3 10.2 12.9 15.4 7.7 23.8 27.4 31.6 7.3 17.9 9.3 13.1 25.9 27.5 32.1 33.0 40.9 13.0 19.2 28.6 31.8 9.7 16.4 24.3 2.5 35.5 31.1 14.9 22.6 28.6 9.4 10.7 3.6 7.0 6.8 7.0 10.7 6.1 6.7 7.5 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108121516-108147776 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 267.1" "Cell line enhanced" "Detected in all" "RPMI-8226: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria 870000 Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favourable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 18.8 28.5 8.9 6.9 9.5 5.4 16.9 5.6 11.6 8.5 16.8 8.5 9.4 15.5 8.8 8.9 8.8 7.6 5.1 53.8 7.4 7.4 88.8 267.1 7.3 6.0 9.9 9.9 10.3 27.3 14.3 6.3 3.8 22.4 7.6 13.1 10.6 27.1 15.9 65.0 8.2 10.9 16.4 8.1 7.7 13.9 14.2 7.2 1.7 10.1 32.1 5.2 12.3 6.9 18.8 20.2 2.3 14.7 7.7 20.7 11.6 15.8 13.0 10.3 29.6 33.3 29.5 5.7 15.2 16.3 16.5 19.3 35.8 16.4 8.8 26.2 17.0 16.8 29.8 14.4 18.0 17.5 24.4 25.3 14.8 32.5 23.0 23.9 15.0 26.7 16.0 14.4 27.0 17.5 35.1 13.1 26.3 9.1 14.1 22.3 10.1 29.1 19.7 20.3 85.2 22.6 10.4 16.5 19.6 24.8 32.2 16.6 27.5 19.6 19.5 17.8 10.4 16.2 18.3 4.4 12.9 16.5 7.9 47.9 12.6 0.8 9.8 2.3 15.6 14.7 17.7 18.8 17.6 17.5 20.2 10.2 15.5 14.3 1.0 7.7 14.4 7.0 20.7 11.6 8.9 9.5 5.6 11.6 7.4 7.4 9.9 9.9 22.4 7.2 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159760328-159779055 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 20.4;liver: 31.0" "Cell line enhanced" "Detected in all" "HBEC3-KT: 48.0" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Supported Nucleoplasm,Cytosol 16000000 Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favourable (1.12e-4)" "prognostic unfavourable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavourable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 1.6 2.6 2.7 1.5 1.7 1.6 2.2 2.2 6.3 2.1 4.3 3.2 1.4 4.8 5.7 1.0 0.7 0.7 2.9 3.6 3.0 31.0 1.8 2.5 2.9 2.1 0.7 1.3 1.2 0.9 4.2 3.9 2.3 0.5 0.1 2.4 1.6 1.4 5.1 1.1 1.7 6.6 0.9 4.2 1.1 2.6 13.3 9.5 12.3 8.4 10.0 20.4 12.2 6.9 6.5 44.3 16.9 6.3 11.8 1.5 6.2 7.3 14.7 25.4 25.4 8.9 5.9 3.1 4.8 6.7 18.3 48.0 17.4 3.5 18.8 13.6 10.6 42.2 6.4 7.8 3.7 6.4 3.5 24.2 10.4 7.1 14.6 9.9 8.9 12.4 13.5 12.5 14.9 4.8 8.4 9.9 18.0 34.2 9.1 11.9 6.7 7.1 4.6 2.4 8.9 15.7 4.4 5.4 4.7 7.6 15.8 4.7 8.7 14.4 1.6 15.5 8.1 6.1 7.1 12.3 13.9 8.4 13.7 13.3 15.9 13.8 9.5 13.3 16.0 12.3 3.2 10.0 5.6 8.7 20.4 12.2 ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866908-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 2100000 "Plasma membrane, Cytosol" Nucleoplasm "CAB007783: AB_562242, HPA022434: AB_1844513, HPA022953: AB_1844514, HPA022959: AB_1844515, HPA028758: AB_10603575" "unprognostic (2.21e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (2.83e-1)" "unprognostic (8.94e-3)" "prognostic unfavourable (3.66e-4)" "unprognostic (3.38e-3)" "unprognostic (4.11e-2)" "unprognostic (5.94e-3)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.88e-3)" "unprognostic (1.66e-1)" "unprognostic (9.36e-2)" "unprognostic (3.90e-2)" "unprognostic (4.67e-3)" 38.3 24.0 16.7 26.2 22.9 19.1 35.7 21.5 29.1 22.9 22.2 25.1 18.0 30.7 27.0 24.9 23.2 23.7 28.2 18.4 18.3 33.7 37.8 22.2 23.3 27.4 23.1 17.9 19.0 30.6 27.1 19.5 26.7 49.0 41.3 23.2 15.6 25.4 19.6 10.9 19.6 29.6 27.2 26.2 24.5 24.6 20.7 21.4 32.0 21.3 18.2 24.6 20.3 21.3 16.1 23.9 25.2 26.3 16.0 23.9 21.4 23.2 79.1 37.4 32.2 57.8 54.3 34.4 32.7 35.8 41.2 51.8 40.1 26.8 37.8 21.0 45.8 37.0 48.2 56.0 34.5 34.0 46.1 21.6 45.6 41.7 26.9 34.9 28.3 43.1 16.9 72.4 14.6 43.4 26.6 30.2 34.1 23.7 57.4 19.6 24.3 14.4 37.7 45.2 48.4 42.2 41.4 70.4 38.7 23.3 73.0 25.0 43.5 33.4 46.6 32.2 26.5 32.3 53.6 17.7 22.5 35.9 54.4 27.1 26.1 18.9 20.7 25.2 23.8 22.1 22.5 16.1 19.0 21.3 23.9 13.8 14.6 16.1 10.7 16.0 26.3 13.9 23.9 21.4 16.7 22.9 21.5 27.7 18.3 33.7 23.1 17.9 49.0 21.4 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157875862 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: " "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.17e-4)" 18.9 9.2 18.0 10.0 12.7 1.6 38.7 15.3 12.2 25.2 14.4 7.4 8.4 8.9 24.8 26.8 11.0 16.6 20.5 18.8 18.7 8.6 21.7 18.9 22.5 15.1 10.4 7.9 18.5 12.3 11.3 17.0 14.2 12.3 16.8 10.5 14.3 18.1 13.6 15.6 12.8 11.5 29.2 12.3 9.2 11.8 8.8 10.9 7.5 34.0 14.6 6.9 16.1 32.5 1.4 2.4 3.8 2.6 1.9 10.0 1.6 2.1 4.2 4.9 6.4 25.0 26.1 6.9 15.1 25.2 12.1 13.0 3.3 4.7 0.0 7.0 16.4 5.9 3.5 8.2 13.1 14.5 3.0 8.6 2.5 4.8 19.8 0.6 10.2 32.6 15.6 24.9 31.8 13.2 3.1 2.4 15.3 3.7 0.1 0.2 7.4 7.7 1.4 6.6 1.8 15.8 7.9 4.4 5.4 5.8 3.3 20.7 1.7 2.3 19.0 18.5 6.1 9.1 5.7 1.6 1.2 0.1 19.0 0.5 19.9 3.8 2.6 0.2 1.1 1.7 1.2 1.4 7.8 2.5 1.8 0.8 3.1 1.5 0.8 1.9 2.3 2.4 10.0 1.6 18.0 12.7 15.3 12.2 18.7 8.6 10.4 7.9 12.3 10.9 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol Cytosol "CAB026126: , HPA063761: " "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.2 13.8 10.7 5.9 12.3 9.7 6.1 7.1 8.1 7.6 5.8 27.8 9.7 2.7 10.0 7.7 11.1 10.2 8.6 7.9 4.0 12.0 6.8 3.5 8.6 14.1 10.9 25.5 18.9 11.2 8.6 10.9 10.7 7.2 8.6 6.7 12.8 10.4 9.5 10.4 4.8 5.6 8.3 3.5 21.5 9.6 13.7 11.4 7.7 11.0 5.0 12.1 7.1 6.7 5.2 8.0 5.9 3.4 5.2 3.7 3.8 5.6 5.3 6.7 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Group enriched" "Detected in some" 4 "ASC diff: 15.1;HDLM-2: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.1 15.1 0.4 0.3 0.4 0.4 0.1 0.5 2.2 0.2 0.0 0.2 1.2 0.0 0.1 0.0 0.3 6.6 1.0 0.0 0.0 0.5 0.0 0.0 1.1 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 1.3 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 20.5;RH-30: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favourable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 12.0 6.0 13.6 8.2 9.9 3.8 10.7 14.5 14.2 10.2 14.1 4.7 9.7 10.4 9.3 9.9 13.6 7.6 17.7 5.6 10.0 9.0 9.0 10.3 7.5 4.7 5.9 10.6 7.6 9.8 8.6 15.9 10.6 7.3 12.2 9.1 7.6 12.2 12.0 19.6 29.5 17.8 13.8 5.4 6.5 9.3 11.0 6.4 1.5 9.5 6.9 6.8 13.5 11.8 0.7 3.0 0.5 3.6 7.7 4.6 1.4 1.3 1.5 9.8 3.6 5.8 3.7 4.0 3.0 3.6 5.2 9.1 4.2 5.9 0.0 2.7 4.8 4.6 8.9 4.4 6.7 1.0 5.4 0.6 2.7 7.3 20.5 0.6 0.7 6.2 5.6 3.3 6.7 3.9 1.4 2.5 3.5 3.4 0.3 0.5 11.0 2.6 0.1 17.1 0.9 4.2 8.3 9.7 5.5 2.5 3.1 3.7 1.9 1.0 3.0 4.8 5.7 4.5 2.1 0.7 0.2 1.8 3.0 0.3 3.8 0.4 3.0 0.5 1.2 3.6 0.5 0.3 4.6 2.1 2.3 0.7 3.0 0.7 0.1 7.7 3.1 3.0 0.4 1.4 13.6 9.9 14.5 14.2 10.0 9.0 5.9 10.6 7.3 6.4 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 16.6;NTERA-2: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "CAB025115: , HPA007398: , HPA040384: " "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.6 1.4 0.6 0.4 8.9 0.3 0.5 0.3 0.7 2.4 1.1 0.1 1.3 0.4 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.6 3.5 0.8 3.0 1.6 0.7 0.9 0.5 1.8 1.1 7.0 1.4 0.3 1.3 5.1 1.9 20.5 0.7 1.7 5.5 1.0 1.1 2.0 3.9 6.8 0.5 2.5 2.2 1.4 4.0 0.9 0.6 2.7 0.4 1.4 4.0 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.0" "Cell line enhanced" "Detected in some" "ASC diff: 18.1;ASC TERT1: 12.4;EFO-21: 16.0;HUVEC TERT2: 58.5;TIME: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 3.6;myeloid DC: 5.0" "Group enriched" "Detected in many" 12 "dendritic cells: 5.0;monocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 25.5 5.1 3.2 9.3 4.3 0.2 15.6 1.6 3.6 15.1 20.1 3.7 13.1 4.9 12.7 11.0 12.1 13.9 11.0 15.4 3.7 3.2 13.6 3.4 55.0 19.1 4.9 3.6 5.9 6.1 21.6 2.7 44.1 5.3 12.3 14.7 12.3 6.9 10.6 14.2 8.0 11.1 8.2 3.7 14.8 8.1 3.5 3.6 1.7 12.9 6.8 5.4 9.3 11.2 0.1 5.0 0.3 3.6 0.0 0.1 0.7 0.0 0.2 0.1 0.0 18.1 12.4 0.0 0.8 1.6 0.0 0.0 0.1 0.1 0.0 16.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 2.7 0.0 0.4 5.0 0.0 0.1 0.0 58.5 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 45.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.7 3.2 4.3 1.6 3.6 3.7 3.2 4.9 3.6 5.3 3.6 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151185-74709303 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 71.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409" Approved Supported Nucleoplasm,Cytosol 320000 "Nucleoplasm, Cytosol" "CAB032876: AB_2242229, HPA038391: , HPA038409: AB_10675798" "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.93e-4)" "prognostic favourable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 13.8 10.7 11.8 13.6 25.4 12.1 14.5 11.2 11.8 9.5 9.3 9.0 9.6 8.8 6.6 10.6 29.4 8.9 6.3 15.7 9.8 11.1 19.0 71.9 15.1 17.9 12.3 9.3 5.2 12.6 15.1 23.5 43.2 11.6 8.7 10.8 8.5 13.1 11.4 18.1 20.8 6.4 8.3 13.2 11.3 7.4 11.9 10.3 13.4 20.8 24.1 21.9 12.6 14.7 49.3 23.0 5.4 21.6 6.5 15.7 9.8 37.5 8.5 9.0 12.0 9.0 13.9 20.7 32.6 25.9 25.3 28.4 23.7 39.2 19.7 8.2 13.1 34.4 10.5 34.7 40.6 13.2 12.1 12.5 13.9 25.5 10.3 20.0 5.1 12.8 23.0 18.4 45.9 22.0 9.9 6.4 19.0 21.0 23.5 27.1 2.5 60.0 22.7 15.6 16.9 27.7 20.7 7.1 8.4 14.3 55.8 10.8 37.1 15.1 18.8 8.4 15.5 22.4 26.9 9.2 10.4 22.2 15.9 28.8 5.1 1.3 10.1 1.4 4.5 18.0 10.0 29.7 9.5 8.2 23.0 49.3 7.9 6.5 5.4 6.5 21.6 16.7 15.7 9.8 11.8 25.4 11.2 11.8 9.8 11.1 12.3 9.3 11.6 10.3 ADPGK "ADP-GK, DKFZp434B195" ENSG00000159322 "ADP dependent glucokinase" Q9BRR6 15 72751369-72785846 "Enzymes, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045194, HPA058525" Approved Approved Centrosome "Intracellular and membrane" 35000 Centrosome "HPA045194: AB_10964638, HPA058525: " "unprognostic (5.96e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (8.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (2.22e-4)" "prognostic unfavourable (4.52e-7)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.07e-2)" 15.3 13.5 6.7 16.4 10.7 23.1 13.2 7.8 11.7 10.2 11.3 14.9 11.2 8.9 9.5 14.3 11.1 11.0 12.0 9.3 7.0 9.0 13.3 12.8 18.7 19.8 11.7 6.3 10.7 15.2 4.9 9.1 18.2 13.4 14.2 13.7 20.4 15.8 9.8 7.5 10.9 13.1 8.9 9.8 21.4 10.5 10.7 8.8 19.6 12.0 7.8 21.2 12.3 9.6 14.2 32.0 22.2 30.3 13.8 13.0 22.6 6.6 14.0 7.5 8.8 17.0 12.9 10.1 19.6 19.1 20.5 28.5 7.9 17.7 12.7 14.6 12.2 18.2 21.2 10.2 15.4 12.4 14.5 9.4 4.1 7.4 10.9 21.7 14.1 14.0 6.0 10.8 10.1 11.9 9.9 21.7 12.4 4.2 6.7 9.7 11.1 6.6 7.9 12.2 17.5 10.6 7.8 5.4 5.6 17.9 7.4 9.4 7.1 26.3 9.7 10.3 8.6 39.0 17.7 22.0 41.9 12.6 18.1 21.4 17.1 22.2 30.3 21.9 10.6 21.0 13.0 14.2 9.7 10.7 32.0 12.5 8.5 9.8 12.0 13.8 17.1 24.4 7.6 22.6 6.7 10.7 7.8 11.7 7.0 9.0 11.7 6.3 13.4 8.8 AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551189-141655244 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 37.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: " "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" 8.7 12.0 11.9 8.0 19.0 5.9 10.6 21.3 23.7 8.8 8.9 10.2 8.8 6.4 16.8 17.1 9.5 11.9 6.8 24.5 16.1 12.3 16.0 10.5 8.4 10.0 11.8 18.8 10.8 8.0 15.7 13.3 9.9 14.2 10.1 13.4 10.6 13.5 10.7 8.4 6.8 8.8 15.0 13.9 12.2 9.0 12.9 9.0 7.8 9.8 8.4 15.6 8.4 8.5 4.6 6.4 0.4 5.5 37.9 10.3 5.7 12.2 13.3 13.2 10.9 10.5 13.0 9.0 13.0 12.7 20.9 20.9 10.3 9.5 13.8 11.7 12.4 9.1 18.4 15.1 22.5 16.2 16.4 12.8 6.3 10.2 15.6 8.8 6.9 14.4 13.3 18.3 18.0 16.0 19.0 19.7 10.1 12.3 23.9 4.1 14.0 15.0 15.5 2.3 41.2 13.3 10.4 11.6 15.9 13.5 16.3 13.4 8.7 9.7 8.9 9.7 7.6 12.9 18.7 15.0 14.8 6.6 15.9 4.1 26.6 0.0 2.6 0.4 9.1 5.5 6.5 4.6 7.4 10.3 6.4 2.5 5.5 9.6 0.2 37.9 3.2 2.5 7.2 5.7 11.9 19.0 21.3 23.7 16.1 12.3 11.8 18.8 14.2 9.0 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850084-99924023 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 23.1;skeletal muscle: 85.6;tongue: 34.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 16000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: " "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favourable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 5.0 4.5 2.5 4.7 3.6 2.0 4.2 5.4 6.1 3.4 4.5 2.1 5.4 3.3 4.8 4.2 9.1 4.1 2.6 8.2 2.2 2.3 5.8 23.1 4.2 5.3 2.4 4.2 3.8 3.6 8.7 4.7 4.8 2.9 5.5 4.2 3.9 5.1 8.7 85.6 3.7 4.0 5.4 2.8 4.8 4.4 2.9 1.2 7.1 4.3 34.4 3.4 6.7 3.6 3.0 2.3 3.5 1.6 6.1 4.3 2.1 11.8 3.5 4.2 6.9 7.0 6.6 14.2 3.8 5.6 3.3 5.9 13.3 4.0 15.6 7.3 6.4 6.7 24.6 7.4 6.3 8.3 7.8 9.1 12.2 7.4 4.6 8.0 5.5 8.1 4.8 4.6 3.9 5.2 14.9 1.1 3.4 3.7 9.4 2.5 6.7 4.6 0.0 1.4 0.8 10.1 16.1 10.5 7.3 10.9 10.5 5.8 7.5 5.4 5.3 4.0 5.8 5.4 3.7 4.5 3.5 18.1 7.1 2.1 2.1 0.1 1.3 3.5 4.3 1.6 4.1 3.0 3.2 2.9 2.3 2.9 3.2 3.2 1.5 6.1 0.9 2.1 3.3 2.1 2.5 3.6 5.4 6.1 2.2 2.3 2.4 4.2 2.9 1.2 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.4;fHDF/TERT166: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: , HPA073355: " "prognostic unfavourable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavourable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 11.7 32.3 21.5 8.3 33.1 7.4 12.1 18.7 32.4 26.9 22.1 19.6 19.6 32.0 25.1 53.3 13.8 26.9 22.3 19.4 22.8 21.1 26.4 20.3 24.3 10.7 20.3 23.6 33.1 18.5 1.3 16.6 18.5 22.4 18.5 24.8 17.5 17.4 19.5 25.5 9.1 46.9 17.9 18.6 11.7 27.8 27.7 17.4 12.1 33.4 9.0 14.6 19.3 12.7 6.7 13.8 13.2 9.6 8.9 10.1 5.7 0.0 0.1 13.5 0.0 35.4 23.9 12.6 0.0 0.0 0.0 0.0 27.6 0.0 0.0 11.6 33.8 3.3 29.1 9.6 0.0 0.0 22.6 0.0 0.0 29.0 0.0 0.0 27.4 13.3 12.5 0.0 12.6 8.2 17.4 17.8 29.3 7.3 0.0 6.3 0.0 4.2 0.1 0.0 0.1 8.8 0.0 0.0 0.0 13.4 4.3 15.1 16.9 0.0 5.8 0.0 5.0 0.0 0.0 10.7 10.1 4.4 17.4 0.0 0.0 2.7 5.7 13.2 9.2 9.6 8.7 6.7 5.8 10.1 10.3 5.9 5.0 7.3 11.0 8.9 6.6 13.8 7.8 5.7 21.5 33.1 18.7 32.4 22.8 21.1 20.3 23.6 22.4 17.4 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687423 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 71.5;liver: 63.1" "Cell line enhanced" "Detected in many" "HDLM-2: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA019544 Uncertain Approved Centrosome Centrosome "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 71.5 5.3 2.3 8.1 2.2 8.4 35.2 2.0 3.0 7.4 20.2 2.2 5.9 31.3 4.7 7.1 11.7 4.1 15.8 12.4 2.8 2.4 10.9 63.1 12.1 11.1 2.5 2.8 5.3 47.7 2.5 6.2 4.9 2.6 5.5 3.3 8.9 12.9 6.2 9.5 7.0 33.6 4.0 1.9 6.8 11.0 5.2 1.9 5.1 13.4 7.0 8.8 6.6 4.9 7.0 20.3 33.2 28.4 2.1 2.5 9.8 14.6 20.6 2.4 11.4 17.7 5.5 10.4 9.7 7.7 6.7 5.1 23.3 29.0 4.8 21.9 5.5 39.7 3.4 6.0 0.7 50.0 15.8 7.1 8.5 5.1 12.2 7.5 17.5 5.3 8.4 5.7 3.0 3.4 8.6 0.8 2.8 26.4 0.5 23.3 6.2 37.5 10.9 8.8 26.6 7.8 9.3 5.5 8.8 12.6 13.3 15.9 8.4 29.5 6.8 8.9 9.1 2.8 6.2 1.2 0.1 3.1 0.1 16.1 8.8 6.0 28.4 33.2 2.2 25.3 2.1 4.1 1.9 2.5 14.9 7.0 1.6 1.8 19.1 2.1 22.2 20.3 2.3 9.8 2.3 2.2 2.0 3.0 2.8 2.4 2.5 2.8 2.6 1.9 AGPAT3 LPAAT-gamma ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865186-43986536 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.36e-2)" "prognostic unfavourable (8.31e-4)" "unprognostic (5.50e-2)" "unprognostic (4.56e-3)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (4.88e-2)" "unprognostic (9.72e-3)" "unprognostic (2.14e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (2.84e-1)" "prognostic favourable (2.29e-4)" "unprognostic (1.50e-2)" "unprognostic (8.91e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" 12.0 10.2 21.5 11.1 23.0 5.8 12.7 14.6 22.7 6.4 20.1 18.9 8.5 27.4 5.1 10.4 13.4 8.1 8.6 11.6 19.9 15.1 33.8 30.2 9.9 9.0 21.7 11.4 5.4 12.7 17.1 7.3 7.6 13.6 7.9 7.6 10.6 24.0 8.0 59.1 10.2 34.6 5.8 25.2 10.2 11.1 11.7 11.4 7.2 14.1 15.0 7.0 9.8 6.6 1.3 4.5 2.4 10.6 0.7 3.5 2.0 26.7 15.2 3.8 10.4 7.7 8.5 2.9 12.4 15.5 15.8 9.7 15.0 19.6 9.1 9.4 14.7 10.4 6.6 13.7 4.6 43.1 17.5 4.0 9.4 20.1 13.5 14.5 9.1 10.1 11.8 13.9 5.8 11.8 22.3 15.0 5.7 11.6 0.1 9.0 1.8 10.9 15.0 4.3 24.4 12.5 26.4 13.2 9.6 15.1 17.2 11.5 11.9 15.9 17.5 10.0 0.1 14.9 12.6 12.0 17.9 5.7 13.0 29.2 9.1 0.0 4.1 2.4 1.5 8.9 1.5 1.3 2.1 2.2 4.5 1.2 1.7 1.9 1.0 0.7 10.6 1.1 3.5 2.0 21.5 23.0 14.6 22.7 19.9 15.1 21.7 11.4 13.6 11.4 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129979-161274061 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.0" "Cell line enhanced" "Detected in many" "AF22: 19.8;HEL: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: , HPA060525: " "unprognostic (5.69e-2)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavourable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 5.6 4.2 10.5 3.5 19.1 8.0 4.5 9.6 26.6 5.3 4.2 35.6 1.0 2.6 10.7 4.5 5.2 7.2 8.0 2.9 14.2 11.8 5.2 2.0 6.1 2.0 25.8 12.4 10.0 2.3 1.3 9.8 14.6 27.4 3.7 4.4 0.7 2.7 4.9 2.1 1.9 2.5 8.5 49.0 5.2 3.0 4.2 19.8 0.6 4.8 2.0 2.2 4.0 3.8 1.1 1.9 0.6 3.5 5.8 7.0 2.1 0.3 0.8 19.8 3.9 3.7 7.6 0.8 0.7 0.2 1.5 2.5 1.1 3.5 0.5 1.4 3.1 0.3 3.6 3.0 1.4 2.2 6.2 14.8 3.5 0.0 2.9 0.1 2.1 9.1 1.5 4.0 2.1 4.6 7.3 6.8 1.8 0.0 1.0 1.6 4.7 7.6 0.0 0.9 0.4 4.3 0.3 11.5 4.4 3.0 1.6 0.8 0.8 1.0 5.1 2.1 2.6 1.4 3.3 0.5 0.7 0.0 7.8 0.8 1.3 0.0 3.5 0.0 7.0 2.8 2.3 0.4 3.3 4.1 1.9 1.1 1.7 2.7 0.6 5.8 2.5 1.5 2.9 2.1 10.5 19.1 9.6 15.8 14.2 11.8 25.8 12.4 27.4 19.8 AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708357-6759666 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favourable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavourable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" 5.9 12.5 20.0 8.5 20.7 5.1 9.8 10.0 21.2 6.0 12.2 16.5 6.8 9.3 9.3 19.1 8.4 9.7 5.9 4.0 19.3 16.9 14.2 14.3 5.1 16.8 18.7 9.5 6.4 16.2 11.4 18.5 16.3 14.2 11.0 12.3 3.3 5.4 16.0 10.2 5.1 8.4 8.6 30.6 8.6 11.0 30.8 12.7 14.3 7.3 6.8 10.4 7.3 5.7 11.0 8.4 3.0 4.8 5.3 3.9 2.9 9.2 7.4 11.7 6.9 3.1 5.0 10.4 4.9 5.1 7.4 7.1 4.6 7.3 20.2 3.3 3.2 11.0 8.9 9.9 12.9 4.4 6.1 24.9 5.8 10.4 7.8 10.4 10.9 6.6 8.4 7.2 9.6 12.8 18.4 10.9 12.1 6.0 18.8 12.8 20.4 5.8 13.6 14.1 7.9 6.7 13.1 23.9 12.5 4.7 8.7 9.3 3.9 13.7 5.3 12.0 5.7 4.6 13.6 4.1 12.6 11.0 7.1 12.6 14.3 3.0 4.1 2.6 1.9 4.8 3.9 8.7 3.0 3.3 2.7 11.0 2.3 2.7 0.4 5.3 4.2 8.4 2.7 2.9 20.0 20.7 10.0 14.6 19.3 16.9 18.7 9.5 14.2 12.7 AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392644-177559299 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease mutation, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Enhanced Peroxisomes "Intracellular and membrane" 9300 Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavourable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favourable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" 22.9 17.7 13.5 21.2 14.9 28.3 17.1 14.9 13.4 16.0 23.5 17.2 14.1 14.1 22.4 10.5 18.4 12.5 16.0 23.9 14.2 13.5 20.8 21.2 15.2 14.7 17.4 11.8 16.4 21.2 37.0 11.7 14.7 15.0 14.7 24.0 8.0 18.2 10.8 23.2 9.6 17.6 21.3 31.8 17.1 14.5 19.1 13.7 29.5 14.2 14.4 14.5 16.9 20.7 3.4 7.6 11.2 6.8 5.6 6.4 3.0 17.7 11.4 8.1 8.3 10.4 11.4 19.3 13.9 6.9 11.9 11.8 21.2 12.4 20.0 30.4 14.4 19.4 21.8 14.2 15.6 26.4 7.4 27.8 19.8 24.9 10.6 30.1 29.6 9.9 9.0 19.1 15.2 23.8 19.0 12.5 14.3 0.0 24.3 10.2 13.8 18.9 19.5 24.2 12.1 20.3 21.3 10.0 12.1 26.4 2.3 16.4 0.1 12.5 24.4 10.7 36.7 10.9 24.3 16.2 28.0 10.0 9.8 13.5 4.1 3.8 6.1 11.2 4.3 6.7 6.4 3.4 5.5 5.3 7.6 2.1 5.3 3.1 1.3 5.6 6.8 0.7 6.2 3.0 13.5 14.9 14.9 13.4 14.2 13.5 17.4 11.8 15.0 13.7 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine-glyoxylate aminotransferase" P21549 2 240868479-240880502 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "liver: 247.3" "Cell line enriched" "Detected in some" 5 "Hep G2: 13.1" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles 5200000 Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favourable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 247.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 13.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.8 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 AGXT2 AGT2 ENSG00000113492 "Alanine--glyoxylate aminotransferase 2" Q9BYV1 5 34998101-35048135 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "kidney: 63.2;liver: 63.3" "Cell line enriched" "Detected in single" 11 "T-47d: 3.5" "Group enriched" "Detected in some" 112 "liver cancer: 9.2;renal cancer: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037382 Enhanced 7300 "HPA037382: AB_10670851" "unprognostic (2.61e-1)" "unprognostic (1.40e-2)" "prognostic favourable (7.47e-4)" "unprognostic (8.24e-2)" "unprognostic (1.28e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.0 63.2 63.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866480-127877743 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 84.5;skeletal muscle: 279.0" "Cell line enhanced" "Detected in many" "U-2197: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006456, CAB009893" Enhanced Supported Cytosol 32000000 Cytosol "CAB009893: AB_2225151, HPA006456: AB_1078116" "unprognostic (6.07e-3)" "unprognostic (1.44e-2)" "unprognostic (2.36e-2)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" "unprognostic (3.09e-1)" "unprognostic (1.52e-2)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-3)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "prognostic favourable (7.31e-4)" "unprognostic (2.62e-1)" "unprognostic (8.40e-3)" "unprognostic (6.99e-3)" 7.7 9.2 19.6 3.7 18.8 6.5 3.9 9.8 17.3 10.5 8.6 18.1 12.2 5.2 3.4 17.3 9.0 84.5 12.0 60.4 17.6 18.5 6.3 10.7 18.7 2.2 16.4 15.3 12.3 4.6 5.6 7.1 2.9 17.5 5.2 10.8 7.0 13.4 15.7 279.0 3.4 2.6 6.3 11.5 5.6 5.8 9.8 11.1 0.0 10.5 61.5 4.0 4.4 4.4 1.2 3.4 2.8 0.4 1.4 1.5 1.2 15.2 6.6 8.4 11.5 20.5 41.8 7.7 10.6 10.7 18.9 11.5 4.8 9.7 0.4 11.6 21.8 22.0 0.0 11.8 7.6 2.4 7.3 2.2 18.9 8.4 11.5 0.0 0.3 31.7 23.0 14.0 10.2 25.2 8.9 0.6 21.4 14.5 0.0 0.3 3.0 20.4 0.4 8.5 3.3 12.6 1.1 13.7 8.5 28.0 16.1 8.1 12.9 9.1 20.8 13.2 5.4 46.5 10.1 1.0 0.1 0.0 16.6 0.0 9.2 0.9 0.4 0.4 1.5 0.3 1.1 0.3 0.6 1.1 0.1 1.2 0.3 1.1 2.8 1.4 0.4 3.4 0.3 1.2 19.6 18.8 9.8 17.3 17.6 18.5 16.4 15.3 17.5 11.1 AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007940-33080996 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018479 Approved 5500000 "HPA018479: AB_1844676" "prognostic favourable (4.37e-4)" "unprognostic (3.25e-2)" "unprognostic (2.80e-2)" "prognostic unfavourable (8.65e-4)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "prognostic unfavourable (9.32e-4)" "unprognostic (7.86e-3)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "prognostic unfavourable (6.40e-4)" "unprognostic (4.95e-2)" "unprognostic (8.33e-3)" "unprognostic (9.56e-3)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-3)" 24.9 27.1 16.0 27.6 20.3 18.3 24.2 19.1 17.6 21.4 31.3 24.6 22.4 36.6 20.6 22.8 31.6 17.6 25.0 33.9 15.1 14.5 51.2 46.5 17.9 18.2 23.1 9.9 24.3 23.2 27.2 16.2 18.6 19.7 22.4 31.8 20.4 31.4 21.5 73.8 20.6 37.1 18.7 25.9 24.7 24.0 29.3 25.0 40.2 37.4 34.4 28.7 26.7 23.3 31.7 51.9 50.9 41.2 27.4 24.4 43.1 44.8 20.0 18.9 21.9 13.1 16.4 19.2 25.4 19.6 38.2 40.2 38.3 40.8 83.7 30.1 18.8 32.6 43.8 43.1 41.2 36.5 32.0 55.4 38.4 29.1 30.6 98.6 31.4 16.2 32.6 32.7 66.1 26.1 58.8 31.5 22.6 22.6 37.3 54.5 26.4 30.7 43.5 32.1 55.1 37.6 27.1 27.8 16.3 29.0 32.2 80.9 26.2 70.1 19.0 23.2 28.0 35.6 47.4 32.9 43.0 78.0 31.5 93.3 26.7 11.0 41.2 50.9 22.0 37.4 23.0 31.7 20.6 20.6 51.9 27.7 21.2 19.8 11.3 27.4 31.5 39.1 24.4 43.1 16.0 20.3 19.1 17.6 15.1 14.5 23.1 9.9 19.7 25.0 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709559-4742043 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.0;HEL: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria 68000 Mitochondria "HPA063324: " "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favourable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 24.6 25.1 20.9 9.8 22.4 6.8 24.0 14.6 17.5 17.7 23.7 15.3 16.0 24.4 18.9 17.5 28.3 14.0 16.1 90.0 22.4 16.4 37.7 75.1 16.4 13.1 25.2 15.2 22.4 15.7 16.9 14.1 13.0 22.9 19.0 23.0 17.4 14.5 19.1 72.0 18.1 22.0 21.2 24.1 12.1 22.5 9.3 24.9 15.2 20.8 32.8 14.9 20.1 17.1 7.0 14.4 17.0 5.6 14.7 17.1 10.2 8.7 7.3 12.5 5.1 17.5 12.9 0.9 11.0 26.0 6.9 10.4 1.2 9.7 8.1 3.8 14.0 5.6 9.1 10.6 11.8 85.0 6.9 54.4 13.0 22.0 13.8 5.7 2.8 20.4 9.5 5.9 8.2 20.3 4.1 11.1 20.7 5.2 5.5 16.5 11.2 2.7 7.4 4.5 4.0 20.2 12.2 20.7 13.0 12.9 4.2 7.4 5.8 11.4 12.6 5.8 5.9 15.2 8.6 2.8 1.8 10.0 10.6 4.3 4.1 6.8 5.6 17.0 16.2 4.4 14.7 7.0 12.5 14.8 10.5 6.9 16.6 17.1 1.9 14.7 3.4 14.4 16.7 10.2 20.9 22.4 14.6 17.5 22.4 16.4 25.2 15.2 22.9 24.9 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 89.7;liver: 50.7" "Cell line enhanced" "Detected in many" "Hep G2: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 6.1;myeloid DC: 5.3" "Group enriched" "Detected in many" 7 "dendritic cells: 5.3;granulocytes: 1.6;monocytes: 6.1" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" 18000 Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavourable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavourable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavourable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavourable (4.36e-4)" "prognostic unfavourable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 12.4 1.6 11.7 3.7 11.2 2.7 13.4 12.0 9.9 4.0 9.5 4.0 4.7 2.7 3.9 4.4 12.3 4.2 8.6 26.0 9.3 7.1 89.7 50.7 1.6 1.4 6.3 9.1 5.8 1.8 8.2 2.6 4.5 7.2 8.9 7.7 4.4 9.4 7.3 2.2 14.0 3.5 13.6 8.1 1.2 7.8 6.0 5.0 0.4 1.9 5.7 3.2 12.4 7.4 0.5 5.3 1.6 6.1 0.6 0.5 1.4 20.2 1.4 1.6 6.9 15.3 14.6 3.5 3.4 4.3 7.4 20.8 30.4 2.4 10.9 9.0 5.3 13.1 5.4 25.6 30.0 9.1 6.2 10.6 6.8 58.2 0.7 8.2 1.3 8.1 14.4 7.3 21.4 0.2 13.1 0.1 11.3 8.7 0.3 0.3 7.1 12.2 0.0 11.9 1.9 11.0 0.9 5.9 4.5 6.1 0.4 4.8 8.5 3.6 1.2 12.4 10.7 0.9 5.8 11.5 5.1 0.6 20.1 3.0 0.7 1.6 6.1 0.0 0.2 1.4 0.4 0.5 0.2 0.5 5.3 0.4 0.2 0.2 1.0 0.6 0.2 0.8 0.1 1.4 11.7 11.2 12.0 9.9 9.3 7.1 6.3 9.1 7.2 5.0 AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282051-77559969 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 95.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.7;BJ: 20.3;fHDF/TERT166: 23.1;LHCN-M2: 58.2;U-2 OS: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 10.9;naive CD4 T-cell: 14.2" "Group enriched" "Detected in many" 15 "dendritic cells: 10.9;T-cells: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" Cytosol "Centriolar satellite" "HPA019128: AB_1844682, HPA057255: " "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (6.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "prognostic favourable (3.88e-4)" "unprognostic (3.56e-3)" "unprognostic (6.17e-4)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (6.76e-2)" 1.8 2.1 43.8 1.9 35.7 3.7 14.1 1.3 95.5 2.0 1.8 20.4 0.0 1.8 1.6 1.5 1.8 1.8 1.7 1.5 35.8 11.8 2.0 1.2 1.4 2.5 13.0 41.1 1.5 2.1 2.4 1.4 1.8 11.4 2.7 1.8 0.0 3.1 2.7 1.3 2.4 1.7 1.7 14.2 2.4 2.9 7.3 13.9 0.0 1.7 0.0 2.1 1.5 0.4 0.8 10.9 0.7 0.7 0.1 14.2 1.9 0.0 1.1 0.8 0.0 10.9 29.7 0.4 20.3 4.3 3.3 1.4 0.1 0.5 0.1 0.1 23.1 0.1 0.0 0.0 1.7 0.7 0.2 0.1 0.1 0.0 0.5 0.1 0.0 3.6 0.1 0.6 1.3 9.5 0.2 0.2 58.2 0.2 0.0 0.1 1.1 7.4 0.5 2.1 0.3 9.0 0.3 4.5 1.1 0.0 0.0 1.2 0.1 0.1 2.3 8.0 18.2 0.4 0.6 4.7 4.2 0.0 1.6 1.0 2.9 0.7 0.7 0.0 3.4 0.1 0.5 0.8 3.2 1.6 10.9 0.8 14.2 7.8 0.5 0.1 0.2 1.2 1.4 1.9 43.8 35.7 1.3 47.1 35.8 11.8 13.0 41.1 11.4 13.9 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavourable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 27.6 27.7 25.1 16.9 25.4 14.8 23.3 21.5 23.6 17.6 22.7 11.3 16.4 18.3 18.3 30.4 26.7 15.4 15.1 17.9 23.2 22.2 30.2 42.3 17.0 18.7 20.9 16.2 18.8 17.2 15.8 26.3 21.5 23.3 18.2 20.6 12.3 14.5 14.6 41.4 11.9 24.0 16.7 19.6 21.8 17.0 46.1 17.5 25.2 24.3 24.2 18.8 19.7 13.7 22.2 22.0 14.3 15.9 16.6 21.2 10.0 17.2 9.6 12.6 16.8 20.7 13.8 23.7 26.0 9.8 12.8 15.9 26.8 14.9 37.0 24.6 11.8 5.8 19.7 12.4 19.6 15.1 9.5 18.2 20.5 20.4 16.9 21.6 7.9 8.0 16.4 12.7 18.3 8.3 17.0 12.2 16.4 20.0 19.9 14.6 10.5 6.4 23.4 15.7 20.5 20.1 14.1 6.5 6.4 13.4 10.8 18.6 11.5 24.4 10.9 9.6 15.4 17.9 21.5 14.7 30.6 32.8 12.4 31.8 12.4 13.7 13.0 14.3 15.5 15.9 16.1 22.2 18.4 19.3 18.0 18.1 20.1 21.2 2.1 16.6 14.2 22.0 18.1 10.0 25.1 25.4 21.5 23.6 23.2 22.2 20.9 16.2 23.3 17.5 AK7 FLJ32864 ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392111-96489427 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.0" "Cell line enhanced" "Detected in some" "BEWO: 10.4;CAPAN-2: 9.0;MCF7: 28.7;REH: 20.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 17 "basophil: 10.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 10.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003543 Enhanced "HPA003543: AB_1078117" "unprognostic (4.18e-3)" "unprognostic (1.14e-1)" "unprognostic (9.40e-3)" "prognostic favourable (3.18e-4)" "unprognostic (4.98e-5)" "unprognostic (8.41e-2)" "unprognostic (9.81e-3)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (3.65e-4)" "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "prognostic favourable (1.14e-4)" "unprognostic (2.00e-2)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (2.25e-3)" 1.5 3.4 4.0 0.9 12.6 2.0 2.1 0.7 3.1 2.7 2.8 8.4 5.1 2.5 2.8 13.1 2.4 29.0 5.0 1.2 6.7 9.2 7.6 3.0 9.2 1.4 2.3 2.6 4.9 2.9 11.7 17.5 0.9 16.7 1.4 2.2 1.5 1.6 2.9 0.5 7.5 3.1 1.6 2.7 4.3 3.5 17.6 4.2 1.1 4.8 1.3 0.8 1.1 1.5 0.4 0.1 10.6 0.3 0.3 0.4 0.2 0.1 2.9 1.2 1.0 0.5 1.7 10.4 0.1 0.3 0.2 0.1 0.3 9.0 0.2 0.2 0.1 1.1 2.8 0.1 0.1 1.3 0.2 0.2 1.3 0.1 0.5 0.1 0.1 0.1 0.4 1.5 0.0 0.1 0.1 0.2 0.2 28.7 0.2 0.2 0.5 0.6 20.4 0.3 0.3 4.5 0.2 2.0 4.1 1.1 0.4 0.0 2.5 0.1 0.0 0.3 0.1 0.3 0.1 0.4 1.3 0.1 0.1 0.0 0.4 10.6 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.1 0.4 0.2 0.2 0.6 0.3 0.3 0.1 0.1 0.2 4.0 12.6 0.7 3.1 6.7 9.2 2.3 2.6 16.7 4.2 AK8 "C9orf98, FLJ32704" ENSG00000165695 "Adenylate kinase 8" Q96MA6 9 132725578-132878777 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.8;fallopian tube: 17.7;testis: 15.6" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;MCF7: 5.2;RPTEC TERT1: 6.0;T-47d: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "NK-cell: 3.9" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021443, HPA023894" Enhanced "HPA021443: AB_1845852, HPA023894: AB_1845854" "unprognostic (4.14e-2)" "unprognostic (1.20e-4)" "unprognostic (1.31e-2)" "unprognostic (1.70e-3)" "unprognostic (2.16e-1)" "unprognostic (2.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.18e-1)" "unprognostic (3.43e-1)" "unprognostic (1.71e-1)" "unprognostic (7.51e-2)" "unprognostic (1.42e-1)" "prognostic favourable (1.61e-4)" "unprognostic (9.89e-2)" "unprognostic (3.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.43e-1)" 0.5 0.7 1.3 0.5 2.2 0.0 0.5 1.6 1.3 1.6 0.5 0.5 0.5 0.0 1.1 12.8 0.5 17.7 0.7 0.5 1.3 2.0 1.4 0.5 1.1 0.5 1.2 0.5 0.9 0.5 2.5 1.7 1.5 2.3 0.5 0.0 0.9 1.0 1.8 0.5 1.1 0.5 0.5 1.7 0.5 0.3 15.6 0.5 0.5 3.1 0.5 0.5 0.5 0.5 0.1 0.0 0.0 0.0 3.9 0.5 0.0 2.0 1.0 0.6 3.1 0.4 0.8 0.6 0.3 0.2 0.2 0.0 0.4 2.1 0.0 0.7 0.3 0.5 0.2 0.0 0.1 0.1 0.7 0.0 0.2 0.0 1.3 0.0 0.0 1.8 0.9 0.3 0.6 0.2 0.1 0.0 0.5 5.2 1.5 0.4 0.2 0.6 0.0 0.0 0.0 6.0 0.0 1.1 1.2 2.6 0.0 0.4 4.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.3 2.2 1.6 1.0 1.3 2.0 1.2 0.5 2.3 0.5 AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492856-109691217 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA030804: , HPA030805: , HPA031779: AB_10603674, HPA031781: , HPA036324: , HPA036711: " "unprognostic (9.68e-3)" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (2.36e-2)" "unprognostic (3.42e-1)" "unprognostic (7.28e-2)" "unprognostic (1.41e-3)" "unprognostic (6.76e-3)" "unprognostic (1.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-4)" "unprognostic (2.58e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (8.39e-2)" "unprognostic (5.56e-2)" 4.6 4.7 7.7 5.6 8.4 4.7 8.3 13.5 8.7 5.0 6.5 8.5 4.1 5.0 6.3 11.1 6.2 11.3 5.2 6.9 9.1 10.3 7.6 4.5 6.7 5.5 9.4 4.9 6.7 4.6 15.4 33.3 4.4 11.5 5.9 6.7 3.7 7.0 6.3 6.1 5.5 6.2 5.7 11.7 6.5 6.1 22.0 7.7 20.5 11.4 4.1 5.0 5.9 4.4 11.2 2.9 15.1 4.1 4.9 6.4 1.6 2.6 1.8 7.7 13.7 7.2 4.5 5.7 4.0 5.0 4.2 5.8 2.9 5.3 5.6 2.1 3.8 4.6 2.2 4.4 9.0 11.9 4.8 4.2 4.5 2.9 5.9 5.3 2.6 3.6 8.5 7.8 10.2 5.5 4.0 4.7 3.1 5.3 4.6 3.6 1.7 2.9 6.1 4.3 5.2 6.2 5.1 9.4 8.0 4.9 4.7 6.7 6.0 6.5 5.9 4.1 2.7 5.9 2.6 2.5 2.1 3.3 8.2 6.7 2.2 15.1 2.8 6.5 5.1 1.5 4.4 10.5 5.1 6.1 2.0 11.2 6.4 5.5 5.4 4.9 4.1 2.9 3.6 1.6 7.7 8.4 13.5 8.7 9.1 10.3 9.4 4.9 11.5 7.7 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favourable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favourable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.1 30.3 25.0 37.2 19.4 20.1 28.0 27.9 34.0 41.3 33.1 19.8 18.3 18.3 21.5 38.2 19.7 17.7 26.0 18.0 41.8 7.2 13.9 18.1 21.3 21.5 22.6 36.3 28.8 21.9 20.7 13.8 30.8 12.1 20.4 26.4 113.2 28.4 28.9 6.5 21.7 26.8 23.2 12.5 19.1 37.7 28.7 23.9 23.3 30.5 17.5 39.9 33.7 24.6 27.7 13.3 39.4 28.0 22.2 10.7 15.8 23.3 19.1 33.3 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: " "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.4 55.4 21.1 21.7 26.3 32.2 11.7 15.0 22.2 31.1 27.8 24.3 20.9 22.9 13.4 33.1 9.8 23.4 31.3 20.1 21.9 26.7 15.0 35.1 15.3 16.5 17.2 18.1 29.7 18.8 21.1 20.1 6.7 19.3 24.0 17.3 18.7 27.3 8.4 11.4 14.9 18.2 11.5 16.5 24.2 36.8 29.1 17.8 15.4 26.4 12.5 20.8 22.2 6.7 19.0 18.8 17.0 23.5 22.4 19.2 18.8 18.6 20.4 15.5 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavourable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.5 2.4 14.9 0.0 11.0 12.6 7.9 13.3 12.2 8.6 7.6 0.1 9.7 0.0 0.0 16.8 0.3 8.2 5.3 11.4 5.9 6.4 0.3 0.0 0.0 5.7 0.1 2.6 6.5 0.0 10.7 9.7 17.6 0.0 0.1 3.9 0.0 5.0 1.1 6.3 3.7 2.7 9.1 0.1 2.9 0.8 19.1 25.3 0.1 0.0 23.8 0.0 8.0 13.8 15.3 11.8 0.1 11.0 1.3 0.4 2.8 11.2 1.2 12.8 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 ALAS1 "ALAS, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 167.6;liver: 136.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 55.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB017498: AB_2225629, HPA035860: AB_10672992" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (6.21e-2)" "prognostic favourable (1.82e-5)" "unprognostic (3.98e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (5.64e-2)" "prognostic favourable (6.06e-7)" "unprognostic (8.45e-2)" "unprognostic (3.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" 9.2 167.6 7.8 6.7 10.6 39.1 8.9 17.0 15.4 6.0 11.0 12.0 15.3 11.4 6.3 11.8 10.5 4.7 8.7 24.8 8.8 7.0 14.1 136.4 13.5 10.0 7.6 9.9 5.8 6.1 8.5 5.8 13.4 12.2 7.3 11.1 8.3 15.7 16.9 24.6 6.8 17.4 6.5 7.3 6.3 12.2 9.7 5.0 7.5 7.4 11.4 9.6 12.1 7.6 6.8 8.4 55.0 12.2 8.8 11.3 6.3 10.4 16.2 11.5 10.6 18.0 13.4 31.4 15.4 14.3 20.6 20.0 21.6 19.8 9.8 3.9 10.7 6.2 16.5 12.6 16.9 19.0 6.4 12.6 12.8 16.4 25.5 20.4 25.3 16.7 11.9 32.7 10.9 18.8 7.4 8.1 18.7 8.5 9.6 31.0 9.9 28.2 5.8 7.2 15.5 18.1 63.4 6.1 4.0 24.9 12.3 13.9 7.0 29.0 13.5 11.5 11.4 23.7 22.2 12.0 20.8 14.8 12.9 22.1 18.3 55.0 9.2 27.8 6.9 12.2 11.3 6.8 7.2 7.7 8.4 6.0 6.5 7.0 14.2 8.8 10.2 4.8 9.7 6.3 7.8 10.6 17.0 15.4 8.8 7.0 7.6 9.9 12.2 5.0 ALAS2 ASB ENSG00000158578 "5'-aminolevulinate synthase 2" P22557 X 55009055-55031064 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 130.9;placenta: 53.5" "Group enriched" "Detected in some" 87 "HEL: 32.0;K-562: 35.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 6 "plasmacytoid DC: 2.0" "Lineage enriched" "Detected in single" 6 "dendritic cells: 2.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (7.82e-2)" "unprognostic (2.01e-1)" "unprognostic (6.41e-2)" "unprognostic (1.14e-2)" "unprognostic (2.98e-3)" "unprognostic (5.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (8.68e-2)" "unprognostic (4.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.45e-1)" "unprognostic (2.32e-2)" "unprognostic (6.63e-3)" "unprognostic (4.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" 1.7 0.4 0.8 0.4 0.8 130.9 0.5 0.2 0.5 0.3 0.4 0.5 0.0 0.4 0.3 0.3 2.3 1.0 0.5 2.9 0.7 0.7 1.6 2.4 17.3 0.3 1.3 0.7 6.1 2.3 0.3 1.0 53.5 2.3 2.6 0.3 1.0 0.5 0.3 3.7 0.4 0.4 1.1 0.9 22.3 0.3 0.5 0.0 0.4 3.2 0.0 0.3 7.0 6.5 0.3 2.0 0.3 0.1 0.0 0.3 10.7 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 32.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.0 0.0 10.7 0.8 0.8 0.2 0.5 0.7 0.7 1.3 0.7 2.3 0.0 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605929-95656706 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 68.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Supported Mitochondria 23000 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favourable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavourable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 6.3 10.4 7.1 10.4 7.9 5.2 7.7 7.3 9.3 13.7 20.1 7.2 20.5 33.8 9.3 12.3 12.8 8.5 15.2 7.2 6.2 7.1 13.0 28.9 6.6 7.4 6.7 5.3 14.5 40.7 12.7 17.4 14.3 7.7 9.6 19.4 7.9 68.8 20.5 3.5 9.6 45.4 10.0 5.4 8.6 15.2 8.4 5.4 12.7 25.9 9.7 15.9 8.6 8.2 13.1 5.2 0.3 4.0 13.0 16.3 8.0 18.2 17.3 16.6 43.6 22.4 21.7 17.9 21.3 32.1 21.7 27.3 34.6 14.6 62.1 20.0 33.5 24.2 33.3 21.9 24.7 17.6 26.2 19.7 12.3 49.1 14.7 34.3 22.0 22.7 13.5 17.7 34.7 22.7 18.3 13.1 16.2 26.2 31.0 22.1 19.6 17.3 29.2 19.1 21.3 25.3 13.9 16.6 16.5 16.9 13.5 15.7 20.1 16.0 18.8 9.0 14.4 23.2 24.4 15.1 11.2 38.0 17.6 39.8 11.5 0.0 1.4 0.1 15.5 2.7 16.3 13.1 14.2 16.0 5.2 9.0 12.1 13.4 0.3 13.0 4.0 3.1 13.3 8.0 7.1 7.9 7.3 9.3 6.2 7.1 6.7 5.3 7.7 5.4 ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033960-5087379 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: " "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favourable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavourable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" 11.0 22.2 8.7 10.8 12.8 6.6 12.8 9.3 18.8 13.7 16.4 14.9 10.1 14.7 12.1 17.0 11.7 12.4 14.3 8.1 8.8 10.4 18.9 31.6 9.9 12.7 10.5 6.5 10.1 27.9 21.5 13.6 10.7 14.6 10.8 17.2 15.5 20.6 12.0 7.3 9.1 12.8 12.1 9.4 16.2 16.5 19.4 11.4 16.0 15.0 8.7 14.5 12.1 8.7 20.7 24.3 7.8 23.3 20.9 26.5 31.7 6.4 17.6 4.4 8.3 17.0 10.1 8.2 14.5 20.4 19.0 19.0 14.5 23.9 13.7 12.5 18.5 17.4 12.1 14.3 12.9 11.2 13.8 7.7 14.6 29.9 13.9 13.4 13.5 12.3 10.9 14.9 9.4 11.3 9.6 18.0 14.1 17.5 8.6 16.5 16.8 10.1 16.0 6.1 38.2 11.8 7.0 7.5 7.6 15.5 24.3 8.3 15.8 11.0 10.8 8.8 8.2 45.0 12.1 13.1 15.8 9.3 7.3 14.4 12.5 3.3 23.3 7.8 26.5 21.6 23.1 19.8 22.9 25.4 24.3 20.7 21.0 23.7 1.5 20.9 21.2 21.2 21.6 31.7 8.7 12.8 9.3 18.8 8.8 10.4 10.5 6.5 14.6 11.4 ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10, alpha-1,2-glucosyltransferase" Q5BKT4 12 34022281-34029694 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" 6.2 7.0 2.7 5.4 5.9 6.9 6.9 4.0 5.5 5.3 4.6 3.8 3.6 3.4 10.3 5.5 6.0 6.2 3.7 4.6 2.6 2.9 4.6 5.7 5.4 6.7 4.1 1.7 7.1 7.8 7.5 6.1 7.2 3.5 5.8 4.1 8.7 9.0 4.4 4.6 5.1 5.0 4.0 3.5 6.1 5.1 8.0 3.6 17.2 6.2 3.0 9.8 5.8 4.8 2.7 1.8 4.5 2.7 2.1 3.8 1.6 4.5 5.3 3.5 5.8 4.2 3.3 12.4 4.4 4.1 4.7 8.6 7.8 11.0 6.9 6.4 2.2 6.9 6.6 5.6 6.5 11.0 6.3 6.3 5.7 3.1 1.7 9.2 6.7 3.6 3.3 10.1 7.7 3.1 9.6 11.6 3.9 6.2 5.9 5.1 13.0 6.8 5.3 12.6 7.0 2.6 6.8 3.1 2.5 7.6 3.2 5.5 7.8 2.5 6.8 6.6 9.8 8.8 5.5 6.3 11.4 13.3 4.6 3.7 5.2 0.0 2.7 4.5 1.9 1.2 3.0 2.5 2.6 1.1 1.8 2.7 3.1 3.8 0.4 2.1 1.2 1.8 3.0 1.6 2.7 5.9 4.0 5.5 2.6 2.9 4.1 1.7 3.5 3.6 ALG10B KCR1 ENSG00000175548 "ALG10B, alpha-1,2-glucosyltransferase" Q5I7T1 12 38316578-38329728 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (4.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.58e-2)" "unprognostic (7.40e-2)" "unprognostic (8.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.30e-3)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" 8.2 8.5 4.3 4.9 7.0 6.6 9.1 5.3 7.2 6.1 4.4 5.4 9.5 4.2 8.5 6.7 6.9 6.4 6.0 5.8 5.0 2.7 5.9 6.6 6.5 7.3 6.6 4.8 8.7 9.6 8.7 7.8 11.6 4.3 6.1 4.5 10.5 9.3 9.7 5.8 7.7 6.5 4.6 4.5 7.5 6.4 8.9 5.0 10.5 7.4 5.6 6.6 7.7 6.8 3.6 2.6 2.0 2.0 1.4 4.1 1.2 5.0 4.7 6.2 6.2 3.2 5.8 6.4 4.0 2.1 5.4 4.8 1.7 15.4 7.7 7.0 2.0 5.3 5.4 4.4 7.8 5.1 6.9 8.2 8.1 3.5 3.5 10.9 5.8 3.2 5.8 7.6 5.6 3.9 9.1 4.7 4.5 3.8 7.2 8.6 7.8 4.7 2.4 13.4 6.1 4.6 6.3 1.8 6.5 7.1 2.4 4.9 10.7 4.4 3.3 5.7 6.6 5.0 5.0 3.7 9.5 12.3 4.8 7.6 7.2 1.2 1.5 2.0 1.1 2.0 2.2 1.8 1.1 1.8 1.1 3.6 2.2 2.7 0.6 1.4 1.4 2.6 4.1 1.2 4.3 7.0 5.3 7.2 5.0 2.7 6.6 4.8 4.3 5.0 ALG11 "CDG1P, KIAA0266" ENSG00000253710 "ALG11, alpha-1,2-mannosyltransferase" Q2TAA5 13 52012398-52029664 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047214 Approved "HPA047214: AB_10961640" "unprognostic (9.21e-2)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (3.04e-2)" "unprognostic (9.15e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" "unprognostic (8.97e-3)" "unprognostic (8.89e-3)" "unprognostic (7.47e-2)" "unprognostic (2.30e-4)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.03e-2)" "unprognostic (9.71e-3)" 14.7 16.9 11.9 9.6 16.2 14.2 13.8 11.8 17.7 13.9 11.9 12.6 15.9 9.8 15.2 13.0 12.6 12.9 11.3 12.2 13.4 9.5 17.3 20.9 11.5 9.3 13.5 11.5 13.1 15.6 18.4 18.4 19.5 15.7 13.5 13.9 11.4 17.6 13.7 13.0 13.7 15.6 14.2 16.6 11.6 13.1 12.2 12.3 13.8 19.6 7.0 10.3 14.7 11.2 10.4 14.4 14.6 14.1 8.7 13.3 6.4 4.9 6.9 12.1 12.1 10.9 10.7 10.6 13.3 11.2 10.2 8.9 9.4 12.1 9.8 3.6 11.4 10.5 12.5 8.8 13.9 11.6 9.4 23.5 7.5 8.5 10.5 19.7 23.6 9.8 13.2 9.4 11.2 9.1 13.4 9.6 12.4 4.5 9.6 7.3 12.5 5.8 12.4 8.7 6.0 10.1 9.8 5.1 9.4 10.2 9.4 8.3 11.5 11.5 13.0 9.4 7.7 9.7 9.6 5.4 7.6 13.0 6.2 7.4 15.5 14.6 7.4 9.8 11.3 6.0 11.2 8.0 10.2 10.5 8.3 10.4 13.1 13.3 4.1 8.7 14.1 14.4 9.8 6.4 11.9 16.2 11.8 17.7 13.4 9.5 13.5 11.5 15.7 12.3 ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12, alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918458 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003076: , HPA051665: " "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (4.39e-3)" "prognostic favourable (6.09e-4)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (4.27e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.21e-1)" "prognostic favourable (3.60e-5)" "unprognostic (1.62e-2)" "unprognostic (3.00e-2)" "unprognostic (9.89e-3)" "unprognostic (6.32e-2)" 9.8 13.3 9.6 11.3 11.2 8.5 9.9 16.0 12.7 10.9 11.7 16.2 15.7 18.0 13.2 11.5 12.1 11.4 11.0 12.0 10.0 5.8 14.1 22.8 10.8 9.2 11.6 7.9 11.8 17.5 14.7 10.6 11.3 10.9 13.5 7.1 12.2 19.4 10.2 8.7 11.5 14.8 7.7 8.9 11.5 14.5 6.5 14.9 12.6 24.5 10.5 12.8 12.1 10.3 7.6 7.8 17.7 9.4 16.1 12.7 7.9 6.9 7.0 7.4 12.3 14.2 6.6 8.2 7.3 6.5 8.6 6.9 11.4 10.0 3.7 6.7 6.4 12.6 9.0 8.6 4.3 5.9 13.2 3.4 11.7 11.4 16.0 8.5 7.6 10.0 8.9 8.4 12.2 8.2 4.2 9.4 4.5 15.8 8.2 6.9 7.1 6.4 13.9 9.3 9.8 9.0 7.9 5.0 8.2 11.6 22.0 9.0 9.0 7.7 6.3 9.6 7.3 6.6 5.5 8.3 3.8 4.9 10.6 6.5 9.1 17.7 8.8 7.4 12.4 8.2 12.7 5.3 9.8 12.2 7.7 7.6 8.3 9.3 6.9 16.1 9.4 7.8 12.3 7.9 9.6 11.2 16.0 12.7 10.0 5.8 11.6 7.9 10.9 14.9 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13, UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002853 Approved "HPA002853: AB_1078131" "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavourable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 20.6 23.0 18.4 23.2 23.2 19.3 24.8 20.9 25.5 21.1 23.3 21.6 22.0 18.0 26.3 28.5 18.3 22.5 22.2 16.8 16.6 16.2 23.5 31.1 19.7 28.4 22.4 16.1 24.2 18.8 13.0 41.7 18.7 19.5 26.7 26.5 16.3 19.5 25.6 11.2 25.2 25.7 23.5 21.6 31.4 20.1 19.0 20.3 23.6 24.5 14.6 25.8 18.3 20.9 10.2 14.4 21.7 12.5 3.4 11.1 7.1 11.5 13.1 11.8 7.5 7.7 11.0 6.7 9.5 9.8 12.2 15.1 13.2 12.2 10.1 18.2 13.1 6.7 14.0 6.6 12.9 7.2 9.4 5.5 14.9 14.9 11.4 10.1 22.3 13.1 12.5 9.8 21.2 13.2 12.3 29.1 12.1 29.5 8.5 9.1 10.8 18.1 6.6 7.5 14.0 19.5 18.0 7.1 10.5 13.5 8.2 8.2 7.3 9.7 8.9 10.6 5.3 13.6 18.1 14.0 23.2 16.2 11.3 13.4 8.0 21.7 12.4 12.2 7.8 12.5 7.6 8.4 8.9 7.6 14.4 10.2 11.1 9.1 2.5 3.4 9.4 7.5 10.7 7.1 18.4 23.2 20.9 25.5 16.6 16.2 22.4 16.1 19.5 20.3 ALG2 "CDG1I, CDGIi, FLJ14511, hALPG2, NET38" ENSG00000119523 "ALG2, alpha-1,3/1,6-mannosyltransferase" Q9H553 9 99216426-99221956 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041512, HPA041601" Approved Enhanced "Actin filaments,Cytosol" "Actin filaments, Cytosol" "HPA041512: AB_10794380, HPA041601: AB_10794302" "unprognostic (8.86e-3)" "unprognostic (4.39e-1)" "unprognostic (2.37e-1)" "prognostic favourable (8.44e-5)" "unprognostic (9.21e-3)" "prognostic unfavourable (1.56e-4)" "unprognostic (1.06e-2)" "unprognostic (5.94e-2)" "unprognostic (3.31e-1)" "unprognostic (3.66e-1)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "prognostic favourable (2.28e-7)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-2)" "unprognostic (4.81e-1)" 12.5 28.0 9.2 9.4 9.7 10.5 16.4 13.1 12.5 18.8 12.9 11.6 31.1 11.0 15.2 39.2 12.3 15.8 13.9 12.1 8.3 9.5 24.8 45.5 16.0 12.8 10.8 6.5 18.4 43.4 14.7 22.4 22.5 12.0 16.7 14.9 14.7 24.1 32.6 13.3 8.7 15.5 12.6 11.3 15.9 15.0 12.6 9.7 14.8 26.0 9.9 15.8 12.9 11.8 16.8 41.0 18.2 18.5 17.5 26.4 17.8 8.1 11.0 8.1 11.6 30.1 19.6 16.7 16.7 26.6 17.1 14.9 13.1 11.8 8.8 7.8 19.2 32.3 13.7 17.9 17.2 13.3 6.3 5.2 8.7 19.4 36.2 9.2 9.9 21.4 23.4 14.5 26.4 19.1 9.1 19.9 15.8 17.1 4.6 10.9 10.5 15.5 5.4 16.5 13.7 22.9 10.4 8.7 7.1 12.3 22.7 21.5 9.2 7.8 13.6 11.7 11.6 14.9 10.4 18.7 10.1 3.8 22.0 7.3 5.7 18.2 18.5 11.2 18.6 14.6 26.4 16.8 17.7 18.4 23.0 13.3 15.4 15.0 5.0 17.5 12.9 41.0 18.8 17.8 9.2 9.7 13.1 12.5 8.3 9.5 10.8 6.5 12.0 9.7 ALG3 "CDGS4, D16Ertd36e, Not56, NOT56L" ENSG00000214160 "ALG3, alpha-1,3- mannosyltransferase" Q92685 3 184242301-184249548 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045103 Approved "HPA045103: AB_10960547" "unprognostic (3.63e-2)" "unprognostic (2.60e-1)" "unprognostic (2.36e-2)" "unprognostic (1.80e-3)" "unprognostic (3.63e-1)" "unprognostic (7.93e-3)" "prognostic unfavourable (1.58e-5)" "prognostic unfavourable (8.67e-5)" "unprognostic (6.18e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-3)" "unprognostic (6.15e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (9.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (5.02e-2)" 14.2 24.1 7.7 12.2 10.3 11.6 15.4 7.2 12.9 11.5 15.5 13.7 15.2 14.3 12.8 11.2 20.5 11.5 15.4 13.0 7.3 6.5 19.7 74.4 12.9 16.8 11.5 7.3 12.7 37.7 18.4 11.7 26.6 10.2 14.0 16.0 12.4 20.9 13.7 18.9 18.4 16.3 14.0 7.9 14.9 15.0 20.8 10.1 13.9 15.9 14.9 18.8 17.4 15.8 14.2 30.1 6.0 25.4 18.7 18.0 15.5 20.3 17.7 4.8 16.3 19.6 11.2 16.5 11.0 12.5 15.1 12.9 27.1 13.7 17.9 30.0 13.5 24.6 17.5 23.8 9.4 12.9 20.3 16.1 13.6 21.8 18.0 26.0 14.5 13.3 20.0 17.8 25.1 8.2 15.8 36.3 9.7 25.0 12.6 21.1 15.3 23.2 13.1 7.5 71.2 16.9 6.8 12.2 10.3 10.2 40.3 17.5 38.2 14.8 6.5 16.0 10.0 13.9 23.4 19.9 34.9 19.0 14.3 34.2 14.3 0.2 25.4 6.0 16.0 25.0 18.0 14.2 17.3 16.2 30.1 12.3 15.6 15.1 0.9 18.7 19.7 27.4 18.0 15.5 7.7 10.3 7.2 12.9 7.3 6.5 11.5 7.3 10.2 10.1 ALG5 bA421P11.2 ENSG00000120697 "ALG5, dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949775-37000261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol Cytosol "HPA007989: AB_1078132" "unprognostic (1.87e-1)" "unprognostic (1.73e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-3)" "unprognostic (3.01e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (1.57e-2)" "unprognostic (5.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.46e-2)" "unprognostic (3.51e-2)" "unprognostic (3.30e-1)" "prognostic favourable (1.40e-5)" "unprognostic (7.44e-2)" "unprognostic (1.66e-1)" "unprognostic (7.14e-3)" "unprognostic (1.86e-1)" 14.7 18.2 11.8 14.0 14.2 11.3 19.9 10.9 13.7 16.7 16.5 10.3 34.2 13.0 13.5 34.8 11.7 12.4 12.9 13.1 10.0 10.5 18.1 36.7 19.1 28.0 16.1 12.8 11.8 60.4 11.8 11.6 17.0 12.1 12.9 20.8 7.3 30.2 37.0 9.0 11.0 12.6 10.9 15.1 12.9 17.6 7.2 14.2 15.4 25.5 12.1 12.4 12.4 11.1 19.1 45.5 17.7 24.8 22.1 25.2 26.9 10.6 14.3 13.3 13.6 36.6 24.5 9.8 29.6 31.5 25.1 20.5 28.1 37.2 15.3 12.3 17.9 26.4 16.3 22.6 23.4 16.4 32.1 35.3 12.0 17.6 35.8 29.9 18.5 25.7 33.3 20.0 26.8 19.1 16.1 19.2 22.6 19.1 20.1 23.9 13.6 11.7 24.6 16.4 37.6 26.6 20.2 10.6 20.6 12.5 23.2 17.1 14.0 29.7 14.5 14.1 8.0 15.4 18.8 16.4 12.6 20.1 21.7 19.0 23.2 17.7 24.1 10.0 24.4 24.8 24.6 19.1 23.0 24.4 23.6 17.0 21.2 23.2 2.7 22.1 20.2 45.5 25.2 26.9 11.8 14.2 10.9 13.7 10.0 10.5 16.1 12.8 12.1 14.2 ALG6 ENSG00000088035 "ALG6, alpha-1,3-glucosyltransferase" Q9Y672 1 63367590-63438562 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062536 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA062536: " "unprognostic (1.21e-1)" "unprognostic (5.60e-3)" "prognostic favourable (4.86e-4)" "unprognostic (1.59e-1)" "unprognostic (3.45e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (9.46e-4)" "unprognostic (2.07e-1)" "unprognostic (9.81e-3)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (3.90e-2)" "prognostic unfavourable (2.63e-6)" "unprognostic (1.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.61e-2)" "unprognostic (3.41e-1)" 9.7 13.7 9.3 13.5 13.5 8.8 11.6 12.2 12.6 9.9 11.8 10.1 9.0 12.1 11.0 14.3 16.7 9.6 9.1 9.9 11.2 7.1 10.3 14.6 10.0 13.4 8.2 11.1 10.8 11.5 10.6 10.0 14.1 11.6 8.9 14.0 10.2 12.9 11.9 8.0 13.7 13.5 7.5 10.5 14.5 10.0 6.9 8.7 25.9 9.7 8.5 21.7 10.0 11.6 7.5 7.9 24.2 7.4 7.4 10.6 5.6 5.3 4.8 8.5 7.8 10.2 8.8 11.2 6.3 2.2 3.3 3.8 5.6 5.4 13.9 15.2 5.2 10.3 12.4 10.1 6.0 15.6 9.8 10.7 5.5 4.6 5.0 12.7 9.3 7.3 6.1 8.1 3.0 12.5 11.3 11.2 7.7 7.0 12.2 10.7 26.0 7.2 12.5 12.0 16.4 9.5 7.4 7.9 4.3 16.8 17.5 16.5 9.7 7.2 6.8 5.5 5.5 11.6 8.1 9.5 13.3 11.5 5.3 12.7 18.4 24.2 7.4 13.6 8.8 6.6 10.6 7.5 7.2 8.5 7.9 5.6 8.7 9.1 4.3 7.4 6.4 6.5 9.4 5.6 9.3 13.5 12.2 12.6 11.2 7.1 8.2 11.1 11.6 8.7 ALG8 MGC2840 ENSG00000159063 "ALG8, alpha-1,3-glucosyltransferase" Q9BVK2 11 78100936-78139660 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm Nucleoplasm "HPA051898: " "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" 20.2 24.5 18.0 11.2 22.3 9.7 23.7 13.8 17.9 16.5 15.0 20.7 23.9 10.3 14.5 30.9 13.3 18.4 12.3 13.0 15.9 16.0 24.9 40.8 12.8 15.7 16.0 11.6 22.9 23.4 24.2 23.6 21.7 17.1 15.5 19.0 17.6 23.2 19.5 8.2 13.3 13.3 14.8 17.6 13.8 13.1 38.9 16.5 18.2 29.7 13.1 17.4 13.2 11.2 21.9 19.4 3.0 20.3 18.2 19.0 14.9 9.3 25.9 24.9 21.2 21.5 15.2 13.4 13.8 20.7 23.7 23.0 49.0 34.4 22.0 25.6 16.5 27.1 28.9 19.9 38.3 15.8 17.4 26.5 22.8 22.0 14.0 25.3 17.6 12.1 12.8 27.6 13.8 17.2 32.8 22.7 31.6 13.7 21.1 28.5 27.6 13.6 22.5 11.4 52.3 23.8 14.5 7.3 18.3 19.9 32.3 10.0 36.0 20.0 10.5 16.1 18.7 36.2 11.9 16.3 31.6 32.5 8.9 24.8 27.8 0.3 17.5 3.0 15.7 19.5 17.5 21.9 16.0 16.1 19.4 16.6 19.0 17.2 1.1 18.2 20.3 18.7 13.0 14.9 18.0 22.3 13.8 17.9 15.9 16.0 16.0 11.6 17.1 16.5 ALG9 DIBD1 ENSG00000086848 "ALG9, alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavourable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" 19.9 13.5 11.8 11.4 17.9 9.0 16.8 19.3 19.3 16.9 13.7 15.6 15.7 16.2 19.1 15.7 13.8 12.5 14.0 14.3 11.6 13.7 13.7 17.7 12.3 13.5 12.2 11.2 19.2 29.9 21.0 16.5 20.3 14.6 14.7 14.9 17.5 34.3 20.1 11.7 17.3 13.2 15.8 13.2 13.0 14.1 25.0 9.8 15.3 17.4 10.9 15.2 13.8 14.2 7.8 9.5 7.0 7.9 7.1 12.2 6.5 9.7 9.8 19.3 18.9 12.0 11.5 14.7 12.7 10.3 10.5 11.4 16.8 16.6 15.7 18.1 14.2 18.3 10.1 15.3 14.9 12.1 7.9 11.9 5.8 12.3 14.0 13.4 8.3 10.0 10.4 11.0 10.9 10.1 11.9 24.6 17.2 7.2 13.4 11.9 6.4 10.9 12.3 17.2 30.6 11.6 8.7 9.5 16.3 11.2 17.1 6.8 18.5 5.5 9.9 22.2 15.6 10.7 13.6 8.0 6.0 14.8 9.2 16.7 15.0 6.7 5.8 7.0 8.5 7.9 9.4 7.8 8.0 8.8 9.5 6.6 12.2 7.3 2.3 7.1 6.9 9.4 7.7 6.5 11.8 17.9 19.3 19.3 11.6 13.7 12.2 11.2 14.6 9.8 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921566 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1;pituitary gland: 17.9" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 26.4" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 1.8 3.1 3.6 1.2 4.4 0.3 1.1 0.5 8.1 0.7 2.1 2.0 0.0 0.7 0.5 0.5 0.6 0.5 1.2 0.4 3.4 4.9 0.4 0.5 1.1 0.5 2.7 4.2 0.6 0.4 0.4 17.9 0.5 5.5 0.5 1.2 2.4 0.9 0.8 0.3 0.9 1.5 0.9 2.1 0.5 0.8 4.9 0.9 0.0 1.6 0.0 0.3 0.6 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.5 0.0 0.0 0.1 0.3 26.4 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 4.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 4.4 0.5 5.9 3.4 4.9 2.7 4.2 5.5 0.9 ALKBH8 "MGC10235, TRM9, TRMT9A" ENSG00000137760 "AlkB homolog 8, tRNA methyltransferase" Q96BT7 11 107502726-107565746 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Multifunctional enzyme, Oxidoreductase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038724, HPA038725, HPA061514" Approved Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA038724: , HPA038725: AB_10674838, HPA061514: " "unprognostic (2.66e-2)" "unprognostic (3.82e-1)" "unprognostic (8.19e-2)" "unprognostic (3.76e-1)" "unprognostic (4.04e-2)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (4.45e-2)" "unprognostic (7.67e-2)" "unprognostic (1.89e-2)" "unprognostic (7.95e-2)" "unprognostic (2.81e-1)" "unprognostic (2.03e-1)" "unprognostic (2.04e-1)" "unprognostic (2.34e-3)" "unprognostic (1.01e-1)" 9.7 6.7 7.2 14.1 12.6 6.1 11.3 9.9 11.7 8.6 7.4 7.6 9.4 6.7 9.5 7.1 9.8 7.4 6.0 12.4 7.4 7.6 9.2 9.5 7.5 11.5 7.2 5.5 9.9 7.0 13.4 10.0 6.9 7.9 8.9 7.9 8.1 7.7 7.5 12.6 9.7 7.8 9.0 7.0 10.8 6.8 5.8 5.8 9.2 11.1 5.7 12.0 8.9 8.1 3.7 3.3 0.5 4.1 4.8 6.2 2.2 4.9 6.0 6.3 6.8 3.5 7.7 5.1 9.5 7.0 7.0 7.6 11.1 9.0 11.5 5.5 9.1 8.9 9.3 7.6 9.2 10.3 6.1 9.6 2.3 5.1 5.2 12.2 11.9 4.7 8.7 9.0 11.5 8.7 13.6 3.9 5.5 4.4 11.0 6.2 8.2 9.9 10.1 9.7 8.0 5.6 5.4 5.7 6.3 5.4 4.1 4.0 6.8 3.7 8.1 15.3 9.2 5.0 11.8 3.6 3.8 9.0 4.3 8.3 15.0 0.0 2.0 0.5 4.5 4.1 4.3 1.9 3.3 3.9 3.3 3.7 6.2 5.2 0.0 4.8 2.7 2.0 3.5 2.2 7.2 12.6 9.9 11.7 7.4 7.6 7.2 5.5 7.9 5.8 AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425538 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: , HPA077835: " "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" 13.9 25.9 21.3 10.6 23.8 14.1 28.7 12.6 25.0 17.2 21.0 24.5 18.5 21.6 16.6 25.2 20.8 15.3 13.7 17.6 20.6 20.2 35.2 50.0 13.3 19.3 22.3 14.3 20.5 14.0 33.3 13.0 41.6 18.9 14.9 11.8 23.8 12.6 18.6 71.6 11.9 18.8 16.0 25.0 14.3 12.2 36.8 17.5 14.6 18.6 10.1 19.3 15.5 16.9 18.3 10.6 21.4 13.1 11.7 9.7 4.0 17.4 24.4 10.7 19.6 33.4 18.8 9.4 18.9 23.4 25.7 20.2 21.6 16.6 45.6 21.9 25.5 16.4 16.3 14.7 24.6 10.2 16.8 13.8 10.1 23.2 29.3 10.7 16.0 21.8 21.3 20.5 24.6 14.9 14.3 6.3 18.6 11.1 16.0 11.4 5.0 16.8 18.1 21.5 17.1 15.9 18.3 10.7 8.2 44.4 15.6 14.3 46.9 11.2 19.3 24.3 13.3 12.3 12.7 13.6 11.9 24.2 17.6 7.8 11.1 21.4 8.5 10.9 6.9 9.9 9.7 18.3 8.7 7.1 7.8 15.6 9.1 9.5 10.5 11.7 13.1 10.6 9.0 4.0 21.3 23.8 12.6 25.0 20.6 20.2 22.3 14.3 18.9 17.5 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 27.1;ovary: 38.2;testis: 15.2" "Group enriched" "Detected in some" 18 "HEL: 27.6;K-562: 15.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "hippocampal formation: 14.3" "HPA060228, HPA069636" Approved "Nucleoplasm,Vesicles,Centriolar satellite,Cytosol" Vesicles "Nucleoplasm, Centriolar satellite, Cytosol" "HPA060228: , HPA069636: " "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.3 27.1 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.0 0.3 0.6 0.4 0.2 0.4 0.8 0.2 0.0 0.2 1.1 0.3 0.2 0.2 0.2 38.2 8.8 0.1 0.2 0.2 0.3 0.4 0.0 0.2 0.2 0.2 2.5 0.0 0.4 0.5 0.2 3.7 0.3 15.2 0.2 0.2 0.2 0.5 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 27.6 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.2 AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416775-49422753 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 10.2;Hep G2: 29.5;NTERA-2: 5.3;SH-SY5Y: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 8.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005566 Supported Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA005566: AB_1844811" "unprognostic (2.10e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (2.17e-3)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.88e-1)" "prognostic favourable (3.90e-8)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (1.98e-3)" 4.7 10.9 6.6 8.0 8.8 6.0 6.6 16.7 10.4 8.4 10.0 7.4 21.3 10.9 9.2 11.1 3.4 9.7 13.0 16.6 7.4 2.0 21.4 41.2 5.6 2.3 7.6 8.3 14.5 18.5 16.3 10.4 2.5 10.7 9.1 10.1 12.2 9.8 20.0 3.8 5.4 11.0 7.1 5.8 7.9 8.1 2.6 7.4 1.7 8.7 0.4 1.8 6.2 8.1 0.7 5.4 4.7 3.2 8.9 1.6 2.3 0.1 0.5 0.7 0.1 0.4 0.0 10.2 0.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.2 0.2 0.1 0.4 0.1 0.2 0.1 0.0 0.3 29.5 1.1 0.0 0.1 0.3 0.7 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.2 0.2 5.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 7.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 3.2 4.7 0.0 1.9 0.1 0.6 0.0 0.0 5.4 0.7 1.6 1.5 0.3 8.9 0.7 0.5 0.0 2.3 6.6 8.8 16.7 10.4 7.4 2.0 7.6 8.3 10.7 7.4 ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92246234-92401384 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA019358: AB_1844831, HPA021780: " "unprognostic (1.77e-1)" "unprognostic (5.96e-3)" "unprognostic (1.23e-1)" "unprognostic (4.97e-3)" "unprognostic (2.75e-1)" "unprognostic (7.67e-2)" "unprognostic (4.88e-3)" "unprognostic (2.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.52e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.00e-1)" "unprognostic (3.00e-2)" "unprognostic (3.20e-1)" 11.9 11.8 21.4 9.2 29.2 5.8 12.3 15.0 25.5 13.6 12.1 34.9 16.0 10.7 12.6 16.4 11.8 10.0 14.7 9.7 22.7 20.0 25.3 10.1 10.6 11.5 31.1 18.4 13.1 12.7 28.5 10.9 12.2 23.4 10.2 12.6 8.4 12.7 18.4 8.6 14.0 11.3 13.4 23.8 11.4 10.9 19.4 35.0 11.5 17.1 4.5 11.1 13.1 13.3 4.8 4.5 3.1 2.0 3.2 4.9 1.1 17.3 10.6 9.4 14.2 17.4 18.6 10.0 13.6 15.6 13.2 17.4 7.7 26.8 10.0 12.0 20.1 8.4 8.6 14.3 20.2 16.9 7.1 6.3 12.2 6.2 11.9 9.0 14.0 12.6 12.1 15.6 20.6 14.9 8.0 21.6 15.6 14.0 19.1 8.4 10.2 12.0 7.2 11.5 10.7 14.0 15.0 13.0 15.4 19.4 21.9 11.5 9.1 5.1 13.3 25.6 20.7 28.8 13.8 13.6 24.2 12.6 14.8 10.9 29.2 2.8 1.3 3.1 2.7 2.0 2.2 3.9 2.6 3.8 1.1 4.8 2.2 2.8 0.8 3.2 1.6 4.5 4.9 1.1 21.4 29.2 15.0 25.5 22.7 20.0 31.1 18.4 23.4 35.0 ANKK1 X-kinase ENSG00000170209 "Ankyrin repeat and kinase domain containing 1" Q8NFD2 11 113387791-113400418 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.7;tongue: 6.3" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 6.5;RT4: 3.1;U-266/70: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "basophil: 1.4;naive B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA012813 Uncertain "HPA012813: AB_1844832" "unprognostic (5.63e-3)" "unprognostic (6.67e-3)" "unprognostic (5.09e-3)" "unprognostic (6.27e-3)" "unprognostic (5.56e-4)" "unprognostic (7.02e-2)" "unprognostic (2.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.50e-1)" "unprognostic (3.15e-1)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (5.39e-6)" "unprognostic (3.17e-2)" "unprognostic (3.83e-2)" "unprognostic (2.79e-1)" "unprognostic (4.65e-2)" 0.6 0.5 0.6 0.6 2.0 0.4 1.2 0.6 1.4 1.5 0.6 0.6 0.6 0.4 0.7 0.9 0.6 3.3 0.6 0.6 0.6 1.2 0.6 0.6 0.6 1.1 0.6 0.6 1.0 0.6 0.4 4.7 0.6 0.6 1.9 0.1 0.6 1.8 1.0 0.7 9.7 0.6 0.6 2.3 0.9 0.2 1.0 0.6 0.6 1.2 6.3 1.5 0.6 1.2 1.3 0.2 1.4 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.5 0.0 0.4 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.1 0.1 0.3 3.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.0 1.3 0.6 0.0 0.0 0.1 0.0 1.4 0.1 0.2 0.4 0.1 0.1 0.0 0.1 0.0 0.0 1.3 0.2 0.1 0.7 0.1 0.0 0.2 0.0 0.1 0.6 2.0 0.6 1.4 0.6 1.2 0.6 0.6 0.6 0.6 APRT ENSG00000198931 "Adenine phosphoribosyltransferase" P07741 16 88809339-88811944 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026681 Approved Supported Nucleoplasm,Cytosol 1200000 "Nucleoplasm, Cytosol" "HPA026681: AB_1844964" "unprognostic (5.87e-2)" "unprognostic (5.10e-2)" "unprognostic (1.98e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.71e-1)" "unprognostic (1.82e-1)" "unprognostic (6.78e-2)" "unprognostic (8.74e-2)" "unprognostic (9.58e-3)" "unprognostic (1.14e-1)" "unprognostic (2.51e-1)" "unprognostic (4.75e-2)" "unprognostic (1.48e-2)" 22.9 37.1 10.9 33.6 13.2 32.9 31.6 10.1 15.3 22.7 31.1 10.7 33.6 27.1 19.9 28.3 50.7 21.0 30.4 22.5 9.1 8.2 27.7 60.4 30.6 94.2 14.8 10.7 17.9 58.2 19.4 15.6 19.3 11.0 25.1 15.1 13.9 48.2 37.4 26.2 49.8 24.3 18.4 12.1 30.4 27.5 16.0 12.2 37.9 29.5 49.7 35.8 18.5 32.8 65.4 92.1 24.2 70.2 58.2 83.7 104.7 25.4 37.4 7.3 33.0 9.0 17.9 39.1 19.3 17.2 22.8 8.9 38.5 30.9 23.7 37.8 10.9 27.3 12.0 31.7 4.6 16.7 71.6 20.2 17.7 40.2 28.6 13.8 16.5 19.1 34.3 18.1 23.0 28.4 42.4 17.8 11.5 93.8 39.0 40.8 28.2 49.0 42.0 11.4 56.1 25.1 17.3 36.5 22.4 36.8 21.5 20.8 71.0 27.5 18.3 20.6 18.0 16.6 18.9 35.0 29.3 65.2 30.3 36.8 18.1 8.5 70.2 24.2 63.0 57.7 83.7 63.2 81.9 67.5 71.6 65.4 75.9 64.3 4.3 58.2 37.1 92.1 66.1 104.7 10.9 13.2 10.1 15.3 9.1 8.2 14.8 10.7 11.0 12.2 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561100-47571920 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046188, HPA066326" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA046188: AB_2679578, HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 22.2 24.2 10.9 16.5 15.5 41.9 19.5 16.0 13.7 18.0 23.2 21.1 24.1 17.8 21.3 18.4 19.4 18.7 21.0 28.6 12.8 7.3 28.0 49.6 21.8 20.2 16.4 9.5 23.4 35.1 28.1 16.9 25.3 13.5 23.5 15.8 25.4 22.1 18.5 60.8 18.9 23.8 18.6 11.2 27.4 24.2 10.2 16.3 27.7 23.1 23.9 27.3 20.2 16.9 23.9 34.3 36.1 38.4 22.4 29.1 27.5 19.9 28.8 12.3 19.9 18.8 15.0 16.7 16.8 17.8 25.2 23.3 23.4 24.5 11.9 13.9 22.6 28.2 21.8 23.3 14.5 21.8 25.6 11.9 30.5 12.1 26.5 23.6 36.5 19.7 23.7 24.0 21.1 19.4 22.0 23.5 17.0 33.8 17.1 25.4 17.7 32.2 15.9 16.1 26.8 14.4 19.1 14.0 10.8 18.2 16.8 9.9 31.6 17.8 18.4 16.4 18.4 32.7 17.0 30.5 19.5 9.2 21.8 26.7 13.0 23.9 29.0 36.1 29.1 35.4 26.9 21.4 25.5 26.7 34.3 23.9 22.7 26.7 23.6 22.4 38.4 24.7 25.1 27.5 10.9 15.5 16.0 13.7 12.8 7.3 16.4 9.5 13.5 16.3 AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713115 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051306 Uncertain "HPA051306: " "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (1.92e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.58e-3)" "unprognostic (9.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-1)" "prognostic favourable (4.67e-6)" "unprognostic (6.73e-2)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (7.18e-2)" 8.5 13.7 11.8 12.2 22.2 17.6 8.8 14.4 25.7 9.3 11.9 16.5 9.8 13.8 12.8 11.4 14.5 12.6 8.4 12.3 11.3 9.7 17.5 9.8 12.1 12.0 8.6 8.4 11.9 15.7 19.4 9.5 11.9 13.3 10.0 15.0 18.3 14.9 9.8 17.9 10.7 16.0 10.1 11.1 12.3 12.0 20.0 7.2 17.1 18.6 11.2 14.9 11.2 10.8 3.2 7.0 9.7 7.6 4.6 7.3 4.5 12.1 15.3 15.2 15.4 13.3 9.6 13.1 13.0 15.3 16.6 16.0 12.8 14.8 10.4 7.0 18.5 15.8 17.5 14.1 21.8 18.6 8.6 16.0 10.2 8.0 8.7 11.3 15.9 12.3 10.3 12.0 13.0 15.6 12.3 11.7 21.3 15.2 11.9 4.9 10.2 15.9 12.7 17.6 6.5 12.7 27.9 16.6 21.8 11.9 15.9 8.4 13.8 12.0 21.8 16.2 19.1 9.6 15.9 14.1 20.7 21.4 19.2 8.6 12.2 2.1 4.8 9.7 7.3 7.6 5.4 3.2 4.2 6.0 7.0 2.1 4.6 3.8 9.7 4.6 4.1 2.3 3.8 4.5 11.8 22.2 14.4 25.7 11.3 9.7 8.6 8.4 13.3 7.2 ARIH1 "ARI, HARI, HHARI, UBCH7BP" ENSG00000166233 "Ariadne RBR E3 ubiquitin protein ligase 1" Q9Y4X5 15 72474326-72602985 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003295, HPA073245" Approved Approved "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA003295: AB_1845017, HPA073245: " "unprognostic (3.31e-2)" "unprognostic (1.92e-1)" "unprognostic (2.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.21e-2)" "unprognostic (5.45e-2)" "unprognostic (1.73e-1)" "unprognostic (9.43e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.96e-2)" "unprognostic (9.19e-2)" "unprognostic (1.78e-1)" "unprognostic (2.93e-1)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (5.70e-2)" 15.3 15.6 11.4 17.4 15.5 24.6 13.3 20.4 21.5 15.8 14.5 10.4 14.0 17.0 21.1 11.2 14.2 12.3 14.4 19.7 10.5 10.5 10.9 10.5 13.7 9.3 10.1 15.0 17.3 13.5 12.9 14.0 15.4 12.6 14.0 7.6 13.0 13.2 13.1 68.3 16.3 13.5 15.8 10.7 11.4 12.5 55.2 10.0 16.9 11.7 13.0 12.7 18.4 20.4 1.9 1.1 4.6 1.5 2.1 2.5 0.3 9.3 9.9 9.7 5.7 5.0 3.6 11.5 10.6 3.8 4.8 3.3 10.0 8.1 9.2 15.9 4.5 13.5 10.0 5.5 2.7 16.3 6.9 6.9 12.2 6.6 3.6 10.3 8.1 4.2 1.9 5.3 6.9 3.5 7.2 11.0 4.7 6.1 10.0 4.0 10.5 3.6 11.4 11.9 5.2 2.7 15.8 9.1 10.4 13.8 6.2 16.2 5.0 11.9 9.1 7.9 11.1 30.6 14.7 11.5 23.2 10.7 5.2 9.5 8.4 4.6 1.0 2.2 1.7 1.5 1.5 0.7 1.3 1.1 0.7 1.9 1.6 1.5 3.4 2.1 0.7 1.1 2.5 0.3 11.4 15.5 20.4 14.0 10.5 10.5 10.1 15.0 12.6 10.0 ARIH2 TRIAD1 ENSG00000177479 "Ariadne RBR E3 ubiquitin protein ligase 2" O95376 3 48918821-48986382 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067381, HPA069715, HPA070963" Enhanced Nucleoplasm Nucleoplasm "HPA067381: , HPA069715: , HPA070963: " "unprognostic (7.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.74e-1)" "unprognostic (2.55e-1)" "unprognostic (4.79e-3)" "prognostic unfavourable (1.70e-4)" "unprognostic (1.90e-2)" "unprognostic (4.01e-2)" "unprognostic (5.01e-2)" "prognostic favourable (7.31e-4)" "unprognostic (5.01e-3)" "prognostic favourable (6.60e-4)" "unprognostic (1.15e-1)" "unprognostic (7.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.39e-2)" 15.0 16.2 14.1 12.8 20.6 16.0 19.2 22.7 22.5 14.1 18.6 25.4 13.9 10.0 18.7 29.2 14.9 16.2 12.8 38.5 15.8 14.9 14.3 17.2 14.5 17.8 24.7 18.3 18.3 20.5 23.1 19.8 15.3 19.7 16.5 15.5 19.2 13.2 19.5 71.3 11.4 14.4 23.0 18.8 17.5 15.7 27.5 21.4 17.7 18.7 15.2 17.2 16.4 14.1 20.6 21.7 27.6 24.5 15.8 32.6 25.3 14.2 14.4 13.9 19.6 20.6 11.3 18.8 16.8 19.6 21.0 23.3 15.0 12.7 29.1 7.9 17.9 8.6 28.5 17.1 25.8 19.5 17.3 29.9 19.0 12.3 18.6 22.1 14.4 12.1 25.9 26.2 35.6 15.7 23.6 20.0 18.6 9.8 22.3 9.1 23.6 21.8 8.3 15.9 24.2 12.3 19.2 6.1 16.4 16.5 20.7 16.1 10.5 15.7 15.0 12.8 18.5 19.1 26.3 26.1 50.3 36.8 14.0 18.5 16.0 27.6 24.5 26.2 32.6 21.6 22.1 19.5 20.9 26.7 21.7 20.6 21.6 27.8 17.2 15.8 13.5 18.7 22.9 25.3 14.1 20.6 22.7 22.5 15.8 14.9 24.7 18.3 19.7 21.4 ART1 "ART2, CD296" ENSG00000129744 "ADP-ribosyltransferase 1" P52961 11 3645128-3664416 "CD markers, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 20 "skeletal muscle: 50.9;tongue: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051148 Uncertain "HPA051148: " "unprognostic (3.73e-1)" "unprognostic (4.58e-2)" "unprognostic (3.12e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" 1.5 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.2 0.1 50.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 13.7 0.5 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.4 0.0 ART3 ENSG00000156219 "ADP-ribosyltransferase 3" Q13508 4 76011184-76112802 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 29.1;heart muscle: 55.1;skeletal muscle: 85.2;testis: 42.6;tongue: 27.2" "Group enriched" "Detected in some" 8 "NB-4: 6.1;NTERA-2: 16.5;SK-MEL-30: 7.3" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Region enhanced" "Detected in many" "cerebellum: 29.1" "Cell type enriched" "Detected in single" 5 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 18 "T-cells: 1.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 5 "cerebellum: 1.2" HPA011268 Enhanced "Intracellular and membrane" 45000000 "HPA011268: AB_1845059" "unprognostic (2.45e-1)" "unprognostic (2.84e-2)" "unprognostic (3.12e-2)" "unprognostic (2.77e-3)" "unprognostic (4.53e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.85e-4)" "unprognostic (2.35e-1)" "unprognostic (5.10e-2)" "unprognostic (1.64e-2)" "unprognostic (2.95e-1)" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (6.61e-3)" 3.5 0.6 4.9 0.9 1.9 0.4 0.7 29.1 9.0 1.0 1.3 6.0 0.0 0.6 0.5 1.1 2.5 0.5 0.5 55.1 3.0 0.9 0.5 0.5 0.6 0.5 3.9 2.0 0.5 3.8 0.4 1.1 0.5 2.7 1.0 1.4 0.4 1.3 1.0 85.2 0.5 0.8 0.6 3.0 1.5 0.9 42.6 7.2 0.0 0.5 27.2 0.5 0.6 0.7 0.0 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 6.1 16.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 4.9 1.9 29.1 9.0 3.0 0.9 3.9 2.0 2.7 7.2 ART4 "CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (Dombrock blood group)" Q93070 12 14825569-14843533 "Blood group antigen proteins, CD markers, Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.7;lymphoid tissue: 17.8;placenta: 17.8" "Cell line enhanced" "Detected in some" "AN3-CA: 5.1;HEL: 10.0;Hep G2: 6.0;HUVEC TERT2: 22.9" "Cancer enhanced" "Detected in some" "liver cancer: 3.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "olfactory region: 2.2" "Low region specificity" "Detected in many" HPA075664 Approved "Rods & Rings" "Secreted to blood" 11000000 "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.7 2.0 0.2 1.7 0.2 2.4 2.1 0.2 0.2 1.4 1.3 0.1 1.9 0.0 1.1 3.7 3.1 1.9 6.1 10.1 0.2 0.2 6.6 33.7 2.1 17.0 0.2 0.0 1.3 1.9 0.0 0.4 17.8 0.3 0.8 0.2 0.0 0.7 0.4 1.9 0.5 0.8 1.5 0.2 17.8 0.5 1.4 0.0 0.1 4.6 1.3 1.3 1.3 1.2 0.6 0.6 1.4 0.4 0.6 1.3 0.3 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 6.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.4 0.5 0.3 0.4 0.5 0.3 0.3 0.2 0.6 0.5 1.3 1.4 0.6 0.2 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.3 0.0 ART5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638503-3642316 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 12.1;testis: 33.3" "Cell line enhanced" "Detected in some" "AF22: 3.3;AN3-CA: 3.5;BEWO: 6.1;BJ hTERT+ SV40 Large T+ RasG12V: 3.5;HEK 293: 4.2;U-2 OS: 4.1" "Cancer enhanced" "Detected in some" "testis cancer: 4.5" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "memory CD4 T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Region enriched" "Detected in single" 5 "olfactory region: 0.5" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" "HPA041637: , HPA044099: " "unprognostic (6.32e-2)" "unprognostic (3.26e-5)" "unprognostic (4.09e-3)" "unprognostic (2.06e-4)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-2)" "unprognostic (5.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "prognostic favourable (1.85e-4)" "unprognostic (3.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.96e-1)" "unprognostic (3.18e-1)" 0.8 0.1 0.3 0.3 0.5 0.0 0.8 0.3 0.6 3.3 0.3 0.3 1.0 0.0 3.3 0.9 0.4 1.5 1.2 2.9 0.3 0.2 0.7 0.6 0.9 0.3 0.3 0.3 9.3 0.3 1.7 0.6 1.7 0.5 1.1 0.0 5.3 1.2 0.8 12.1 0.3 0.4 1.0 0.3 0.5 0.3 33.3 0.5 0.3 3.5 5.2 0.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 3.3 3.5 0.0 0.0 6.1 0.4 3.0 1.5 3.5 0.1 0.0 0.0 1.6 0.4 0.0 2.9 0.0 0.8 0.0 4.2 0.0 0.6 0.3 0.1 0.0 2.7 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.6 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 2.9 0.1 1.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.2 0.3 0.3 0.5 0.5 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869516-102901899 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 92.8;parathyroid gland: 30.0" "Cell line enhanced" "Detected in many" "AF22: 14.2;REH: 27.1;SH-SY5Y: 14.6;T-47d: 22.7" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 2.0 92.8 3.7 0.7 8.6 0.5 2.6 4.5 6.4 4.0 2.0 2.2 0.4 1.3 3.8 3.2 2.1 2.1 5.2 10.0 5.7 3.1 7.4 22.4 1.7 0.9 2.8 4.4 3.9 8.7 30.0 2.4 0.5 4.6 4.2 0.8 8.9 2.2 3.4 6.0 1.8 1.3 3.9 2.7 5.6 1.7 3.5 1.6 0.3 3.2 1.0 0.7 1.8 1.8 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 3.9 14.2 8.9 0.3 0.3 2.6 4.1 3.5 6.2 7.6 10.6 0.6 0.2 1.2 5.3 0.2 12.1 0.7 6.4 0.0 3.5 0.0 1.7 10.4 4.1 0.2 0.1 1.9 1.6 0.8 0.0 0.2 0.0 0.2 5.5 0.1 2.4 0.3 6.8 0.6 27.1 0.0 0.1 1.3 0.1 0.4 14.6 0.0 0.2 1.9 22.7 0.3 0.1 1.3 0.0 2.0 0.0 0.3 0.2 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.7 8.6 4.5 6.4 5.7 3.1 2.8 4.4 4.6 1.6 ASH1L "ASH1, ASH1L1, huASH1, KMT2H" ENSG00000116539 "ASH1 like histone lysine methyltransferase" Q9NR48 1 155335268-155562807 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004806 Approved Supported "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA004806: AB_1845087" "unprognostic (2.98e-1)" "unprognostic (3.15e-2)" "unprognostic (1.10e-1)" "unprognostic (1.70e-2)" "unprognostic (2.05e-2)" "unprognostic (4.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (6.84e-2)" "prognostic favourable (3.80e-4)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (2.45e-2)" "unprognostic (1.94e-1)" 20.1 10.1 12.1 17.7 14.5 12.3 14.5 23.6 15.5 15.4 17.7 15.5 20.4 8.2 18.7 12.5 12.5 12.2 10.0 11.0 11.8 10.6 13.0 8.9 10.6 9.4 16.6 11.5 23.5 10.0 24.4 22.6 12.9 13.2 18.9 10.7 10.7 11.8 22.2 21.8 12.8 12.8 17.4 14.5 8.6 10.4 7.8 14.3 15.6 16.8 7.1 10.6 17.8 19.9 11.0 5.7 16.5 5.3 8.6 10.7 1.7 13.6 11.8 7.7 6.7 17.4 18.8 8.7 11.1 11.7 7.6 6.4 8.7 9.2 6.1 11.3 14.5 14.2 12.1 9.8 12.1 6.0 7.8 7.5 11.6 4.7 8.5 8.4 5.9 11.5 10.9 12.7 12.5 9.0 10.7 9.2 12.7 10.7 5.7 4.5 7.3 11.4 5.2 16.0 7.0 8.4 15.1 7.9 11.8 17.5 15.9 8.6 12.7 18.2 13.9 11.8 12.6 11.1 13.7 8.6 4.9 9.8 9.2 6.3 10.1 16.5 5.3 11.0 8.3 3.2 7.9 10.0 7.8 6.3 2.5 11.0 10.7 5.5 12.8 8.6 3.5 5.7 8.6 1.7 12.1 14.5 23.6 15.2 11.8 10.6 16.6 11.5 13.2 14.3 ASMT "ASMTY, HIOMT, HIOMTY" ENSG00000196433 "Acetylserotonin O-methyltransferase" P46597 X 1615001-1643081 "Enzymes, Predicted intracellular proteins" "Melatonin biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.8;epididymis: 7.0" "Cell line enhanced" "Detected in some" "BEWO: 2.9;NTERA-2: 1.4;U-266/70: 2.1;U-266/84: 3.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "pons and medulla: 8.8" "Group enriched" "Detected in some" 4 "memory B-cell: 2.2;memory CD8 T-cell: 2.0;naive B-cell: 3.8;NK-cell: 1.0" "Group enriched" "Detected in many" 4 "B-cells: 3.8;NK-cells: 1.0;T-cells: 2.0" "unprognostic (1.84e-2)" "unprognostic (1.63e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (8.55e-4)" "unprognostic (1.54e-1)" "unprognostic (2.27e-2)" "unprognostic (4.30e-3)" "unprognostic (1.56e-1)" "unprognostic (1.43e-3)" "unprognostic (2.64e-1)" "unprognostic (4.04e-3)" "unprognostic (1.49e-1)" "unprognostic (3.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" 0.6 2.3 0.6 1.2 0.7 2.4 0.8 1.2 0.6 1.3 0.8 0.6 0.6 0.3 1.4 7.0 0.6 0.9 0.7 0.6 0.8 0.7 0.6 0.6 0.8 0.8 1.8 0.6 0.7 1.3 0.7 3.8 0.6 8.8 1.0 0.2 0.6 1.2 1.0 0.8 1.6 0.7 0.9 4.1 1.4 0.6 0.6 0.6 0.6 1.1 0.6 0.6 0.6 0.9 3.8 0.0 0.5 0.0 1.0 2.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 2.9 0.2 0.0 0.6 0.0 0.0 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.1 0.2 0.8 0.1 0.1 0.0 0.0 0.4 0.1 0.1 0.4 0.0 0.0 0.0 1.2 0.0 2.1 3.7 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.5 2.0 0.0 3.8 0.2 0.1 0.5 1.0 0.0 0.0 0.0 0.1 0.6 0.7 1.2 0.6 0.8 0.7 1.8 0.6 8.8 0.6 ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 10.9;AN3-CA: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046816, HPA050999" Approved Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" "Golgi apparatus, Cytosol" "HPA046816: , HPA050999: " "unprognostic (3.98e-1)" "unprognostic (3.18e-1)" "unprognostic (4.30e-2)" "unprognostic (2.67e-2)" "unprognostic (8.86e-2)" "unprognostic (8.18e-3)" "prognostic unfavourable (1.03e-5)" "unprognostic (1.49e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-2)" "unprognostic (1.29e-3)" "unprognostic (1.25e-2)" "prognostic unfavourable (7.78e-5)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "prognostic favourable (1.35e-4)" 4.8 3.8 16.8 5.4 16.8 4.4 4.1 12.5 20.7 5.5 4.9 16.3 3.0 4.6 10.2 21.0 3.2 8.3 5.4 3.9 15.7 15.9 4.4 3.8 3.9 4.8 14.0 12.2 10.1 4.4 4.4 10.6 4.3 13.0 9.8 5.3 4.1 5.4 4.0 4.5 6.9 6.1 4.9 13.5 4.3 7.9 7.0 12.8 3.3 4.3 1.7 5.6 4.0 3.8 1.7 2.6 2.6 1.7 0.7 2.1 0.8 2.0 1.1 10.9 8.1 1.5 1.1 0.4 0.3 0.1 0.4 0.8 2.9 2.1 0.3 1.7 1.7 2.4 4.0 1.4 0.1 1.5 4.7 0.1 0.4 2.7 0.7 0.2 1.3 2.2 0.9 0.7 0.0 0.9 1.6 0.2 2.0 1.8 1.6 0.7 0.7 0.2 0.9 0.3 0.6 2.0 3.0 0.6 4.3 0.7 1.0 0.7 4.4 0.5 0.8 3.1 2.2 0.1 0.8 1.6 2.1 1.0 2.5 4.8 3.2 2.6 1.7 1.3 0.8 1.5 1.0 1.7 1.0 0.8 1.6 1.2 2.1 1.6 0.3 0.7 1.1 2.6 0.9 0.8 16.8 16.8 12.5 20.7 15.7 15.9 14.0 12.2 13.0 12.8 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740421-121928801 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm Nucleoplasm "HPA038444: AB_10672745, HPA057549: " "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favourable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 15.4 16.9 14.6 16.8 18.8 14.7 16.9 23.1 20.8 17.4 18.8 17.6 12.6 13.5 14.4 14.3 15.7 13.6 14.4 27.5 15.0 18.4 23.1 23.0 14.0 11.7 17.6 14.0 14.4 13.4 23.6 22.5 15.0 15.4 16.5 20.0 19.0 14.1 16.6 33.6 12.0 16.2 25.8 15.6 12.9 12.0 18.1 14.6 21.4 22.0 11.2 14.3 22.8 15.2 14.0 14.4 17.1 11.5 9.9 16.0 8.5 9.8 16.8 13.0 11.0 9.0 10.8 8.9 8.7 15.6 10.4 11.0 21.7 12.2 12.1 7.2 9.9 10.1 12.1 8.6 10.1 20.0 10.7 4.3 7.3 17.6 9.2 18.6 10.2 7.9 8.0 10.8 22.9 11.2 6.7 25.2 8.3 6.2 10.1 7.6 6.7 8.1 9.8 13.7 7.1 13.2 8.5 3.7 12.2 11.7 8.3 17.9 6.1 4.7 13.8 6.0 5.9 8.9 15.4 21.9 30.2 14.8 9.3 12.9 5.0 17.1 11.1 14.7 16.0 11.1 15.5 13.0 13.9 13.7 9.4 14.0 15.7 14.3 8.1 9.9 11.5 14.4 13.6 8.5 14.6 18.8 23.1 20.8 15.0 18.4 17.6 14.0 15.4 14.6 ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Enhanced Nucleoplasm Nucleoplasm "CAB003769: AB_562241, HPA022134: AB_1845138" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-1)" "unprognostic (9.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavourable (7.08e-5)" "unprognostic (2.28e-2)" "unprognostic (3.70e-2)" "unprognostic (6.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.02e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (7.21e-3)" "unprognostic (6.70e-2)" 25.3 21.0 25.3 14.3 29.3 14.3 19.7 39.6 33.4 27.5 15.9 18.0 15.7 12.8 22.4 22.6 16.0 19.5 17.9 14.1 25.1 28.0 23.0 26.8 15.2 17.6 23.2 18.4 27.3 19.0 24.0 33.0 19.9 29.6 19.0 16.0 14.9 16.8 19.1 13.9 10.1 13.2 18.3 22.9 17.5 13.8 19.9 18.9 34.6 32.6 10.2 20.1 21.7 16.7 15.0 18.7 24.2 14.8 15.3 22.0 14.3 7.2 6.4 19.0 12.3 17.0 18.2 8.8 11.9 20.4 14.5 21.0 13.8 13.6 10.9 13.1 14.0 7.1 14.4 7.2 22.7 13.5 8.3 15.4 11.7 30.0 19.1 14.2 16.2 13.6 16.3 18.6 22.2 19.9 12.5 17.1 16.2 5.5 23.0 17.8 17.7 14.6 20.1 8.8 16.9 21.2 6.4 15.8 13.1 14.9 4.6 17.5 10.4 15.9 12.5 16.9 8.8 9.0 7.1 16.3 24.6 14.0 13.2 13.6 11.4 24.2 14.4 16.8 18.2 12.8 22.0 15.0 15.7 18.8 18.7 12.7 18.3 19.9 9.3 15.3 14.8 10.5 19.8 14.3 25.3 29.3 39.6 33.4 25.1 28.0 23.2 18.4 29.6 18.9 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311817-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Enhanced "Plasma membrane,Cytosol" 3400000 "Plasma membrane, Cytosol" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavourable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavourable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 19.4 27.4 21.1 23.0 28.4 16.9 24.8 12.1 32.3 20.6 26.7 29.1 18.1 23.4 27.9 15.6 19.1 21.9 19.1 18.2 20.3 21.1 23.1 35.6 17.3 36.1 29.7 19.9 23.4 32.9 25.1 21.1 31.1 24.4 21.9 35.9 19.5 14.4 29.4 35.5 17.0 20.6 26.7 21.7 29.0 20.4 15.0 28.0 46.3 16.1 13.5 35.3 27.6 18.0 21.7 13.4 2.9 8.9 19.6 22.8 10.0 20.2 30.7 17.1 29.1 23.0 23.3 8.6 20.7 18.0 23.7 27.2 59.1 31.8 29.5 25.7 21.6 21.3 37.6 31.2 34.0 21.9 36.4 35.9 26.3 53.0 29.8 44.9 18.4 19.7 24.0 31.6 38.2 15.8 46.3 24.6 32.5 29.9 39.1 21.8 65.9 17.2 36.4 24.7 26.4 25.1 32.7 26.9 18.6 16.6 20.5 23.4 33.6 16.0 13.9 20.1 20.8 25.9 13.0 31.1 40.6 61.2 17.5 25.1 29.0 2.9 6.0 0.1 13.2 8.9 22.8 21.7 18.6 20.0 13.4 13.2 18.9 17.5 0.7 19.6 7.4 11.7 17.7 10.0 21.1 28.4 12.1 32.3 20.3 21.1 29.7 19.9 24.4 28.0 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB000102: , HPA067142: " "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.6 3.8 7.5 4.0 9.8 14.3 1.9 6.0 6.7 3.5 5.8 4.7 6.3 9.4 8.9 4.8 4.0 5.7 5.0 5.4 7.5 3.3 8.5 4.7 4.7 5.1 10.2 9.2 9.2 3.1 5.2 10.2 7.2 8.2 6.4 6.8 1.9 7.0 9.4 6.1 3.8 5.5 5.2 14.8 3.9 5.4 5.1 6.3 6.9 3.2 10.3 4.9 5.8 11.3 8.6 4.8 4.9 5.6 4.3 4.5 47.4 5.7 11.3 9.6 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavourable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.5 11.1 7.4 8.4 10.6 11.6 8.8 12.4 7.0 9.3 9.6 5.2 7.2 18.4 12.9 8.8 14.6 10.9 11.5 14.1 5.9 7.2 10.1 8.4 5.0 4.7 16.9 5.7 9.1 6.4 8.8 10.5 9.6 7.0 8.3 9.5 9.9 12.7 7.0 7.1 7.9 10.6 10.8 13.3 9.4 10.5 5.3 5.3 22.9 8.3 8.1 12.1 6.9 12.4 9.5 4.8 12.3 13.3 10.8 6.4 17.1 12.3 6.6 7.5 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavourable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavourable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 32.5 24.0 16.1 11.3 0.9 2.1 20.4 26.7 12.5 64.7 27.3 67.2 22.8 10.7 18.4 10.9 26.3 28.5 17.9 69.0 9.6 10.9 19.0 24.6 41.8 0.5 25.4 26.8 1.0 1.9 22.4 20.1 15.1 21.5 8.5 27.5 33.2 15.2 19.7 14.7 24.8 11.6 31.1 11.8 10.3 8.6 13.9 7.5 37.3 43.0 17.9 25.5 15.9 8.6 28.1 27.9 15.5 37.6 11.9 13.8 18.5 15.2 14.8 23.2 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Supported Nucleoplasm,Midbody "Nucleoplasm, Midbody" "CAB005862: AB_449204, HPA037708: " "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavourable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.0 28.2 42.0 20.2 0.9 1.4 16.1 19.7 10.6 40.8 37.7 36.5 12.4 41.0 10.2 7.8 30.2 30.5 13.5 33.8 18.0 50.1 24.4 16.1 30.8 0.1 12.9 24.0 0.7 0.6 23.9 15.0 18.8 15.2 15.9 17.9 19.5 46.8 18.3 26.1 12.6 31.7 38.7 17.0 8.9 8.1 9.1 13.0 17.5 7.9 13.4 13.8 8.7 7.3 16.4 16.9 14.7 51.2 11.6 7.7 30.8 7.9 19.6 33.1 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57230802-57235548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 72.0" "Cell line enriched" "Detected in some" 7 "NTERA-2: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034859 Uncertain "HPA034859: AB_10670298" "unprognostic (7.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.45e-2)" "unprognostic (8.07e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-5)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (6.46e-4)" 0.6 0.5 0.9 0.9 1.2 0.7 1.5 0.7 2.0 0.4 0.6 0.6 0.2 0.0 0.8 1.3 0.5 0.6 2.6 0.9 0.9 1.1 0.8 1.8 1.3 2.2 1.2 0.2 0.4 0.5 0.1 1.3 1.2 1.7 0.5 0.8 1.1 0.5 0.9 2.3 0.6 0.4 1.1 2.1 3.4 0.4 72.0 0.6 0.7 0.8 1.0 1.3 0.5 0.4 2.1 1.0 1.7 1.0 1.0 0.6 0.2 0.2 0.1 0.7 0.3 0.2 0.7 0.3 1.2 0.6 0.9 3.4 0.8 0.1 0.0 0.1 0.5 0.0 0.0 0.7 0.6 0.0 3.7 0.1 0.3 0.0 1.1 0.0 0.2 0.9 0.7 0.7 0.5 0.6 0.1 0.0 1.2 0.0 1.1 0.6 29.3 0.8 0.1 0.2 0.6 0.6 1.2 1.4 0.4 0.0 0.2 0.1 0.1 1.3 0.3 0.2 4.1 0.3 0.7 1.4 1.8 0.6 0.8 0.0 0.0 0.0 0.1 1.7 0.6 1.0 0.0 1.9 0.0 0.0 0.9 2.1 0.0 0.0 0.1 1.0 0.3 1.0 0.0 0.2 0.9 1.2 0.7 1.6 0.9 1.1 1.2 0.2 1.7 0.6 AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240627 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 3.8;skin 1: 6.1" "Cell line enhanced" "Detected in single" "HEK 293: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063412 Enhanced "HPA063412: " "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.96e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "breast: 5.7;skin 1: 14.0" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 2.3;PC-3: 2.6;SK-BR-3: 1.1" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA062748 Approved "HPA062748: " "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219203-41261766 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 66.1;U-251 MG: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 8.8;plasmacytoid DC: 18.3" "Group enriched" "Detected in many" 14 "dendritic cells: 18.3;NK-cells: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" 61000000 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: , HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavourable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 38.0 15.4 10.6 11.7 12.7 1.3 27.1 6.3 12.1 26.2 26.8 13.4 8.1 9.1 28.0 19.4 21.8 17.4 17.8 18.5 11.5 6.1 7.8 13.0 20.0 7.6 10.6 9.3 20.9 5.1 9.6 5.6 26.6 10.1 19.5 10.2 16.8 7.8 20.4 14.1 13.8 12.8 29.4 10.7 27.3 16.2 22.4 10.4 3.4 12.0 8.4 5.8 35.6 18.3 0.1 18.3 0.9 0.2 8.8 0.3 0.2 52.5 21.2 1.3 0.1 4.8 4.8 0.0 41.8 37.6 61.4 38.1 1.1 24.7 0.0 17.0 66.1 4.4 0.0 28.1 52.9 0.0 0.0 0.0 14.0 0.8 17.4 0.0 0.0 3.6 0.5 36.2 56.2 22.7 2.0 0.0 38.0 0.0 0.0 0.0 0.5 10.2 0.0 22.4 0.0 27.4 0.0 0.0 0.0 10.8 0.0 0.2 0.1 0.9 46.6 43.5 29.7 41.5 70.8 0.0 0.1 0.1 29.0 0.0 32.3 0.9 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.1 4.2 0.1 0.2 0.2 0.3 8.8 0.1 18.3 0.2 0.2 10.6 12.7 6.3 12.1 11.5 6.1 10.6 9.3 10.1 10.4 B3GALNT1 "B3GALT3, beta3Gal-T3, galT3, GLOB, P1" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105384 "Blood group antigen proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 36.8" "Cell line enhanced" "Detected in many" "PC-3: 16.9;RT4: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.9;NK-cell: 16.7" "Group enriched" "Detected in many" 7 "granulocytes: 4.9;NK-cells: 16.7" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles 290000 Vesicles "HPA041204: AB_10795585" "unprognostic (3.85e-2)" "unprognostic (5.11e-3)" "unprognostic (3.02e-1)" "unprognostic (1.06e-2)" "unprognostic (7.83e-2)" "unprognostic (4.07e-2)" "unprognostic (9.26e-5)" "unprognostic (1.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-2)" "unprognostic (3.44e-2)" "unprognostic (3.24e-1)" "unprognostic (2.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.66e-2)" "unprognostic (3.19e-3)" 3.8 5.4 14.0 3.0 24.5 3.1 7.4 17.2 24.7 15.5 2.3 5.5 2.6 1.5 8.3 6.9 5.4 10.4 7.1 36.8 15.4 21.6 14.3 1.0 10.8 3.5 11.3 16.2 13.8 7.8 6.5 8.5 10.0 17.7 8.9 2.0 7.5 14.8 6.7 1.1 2.2 1.9 7.2 7.6 4.2 7.5 6.2 5.0 1.1 19.5 2.3 3.9 10.5 4.7 1.4 1.4 4.9 0.2 16.7 0.7 0.5 6.6 0.2 3.1 0.1 0.3 1.0 0.1 3.7 3.2 8.1 2.8 4.4 5.0 0.0 14.8 3.0 1.5 0.0 6.4 2.6 0.1 0.0 3.6 2.8 0.0 4.7 0.1 0.1 9.9 1.9 2.2 0.5 11.8 0.0 0.0 3.3 10.7 0.0 0.0 7.4 16.9 0.1 0.0 0.1 3.8 51.5 6.2 0.0 9.3 3.4 2.7 14.2 5.4 0.0 0.1 6.5 0.2 0.1 1.5 0.0 0.0 5.7 0.0 0.0 4.9 0.2 0.0 0.4 0.1 0.4 1.4 0.2 0.4 1.4 0.3 0.5 0.7 0.4 16.7 0.0 1.0 0.0 0.5 14.0 24.5 17.2 24.7 15.4 21.6 11.3 16.2 17.7 5.0 B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235449923-235504481 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 35.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012502, HPA050662" Approved Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Nucleoplasm "Golgi apparatus" "HPA012502: AB_1845228, HPA050662: " "unprognostic (5.50e-2)" "unprognostic (3.16e-3)" "unprognostic (6.60e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (7.59e-3)" "unprognostic (1.96e-2)" "unprognostic (3.39e-2)" "unprognostic (3.38e-1)" "unprognostic (7.19e-3)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (8.34e-3)" 5.0 6.3 3.9 4.3 5.1 1.3 8.4 4.7 4.5 5.4 7.6 3.5 5.1 3.3 8.0 8.7 10.3 6.1 9.7 7.9 2.8 2.9 3.7 4.6 3.7 3.1 3.0 3.2 5.9 35.7 9.8 8.9 4.5 4.7 8.3 5.8 8.5 8.7 7.3 21.6 6.1 6.9 16.9 2.5 3.3 9.2 5.8 3.9 4.7 7.1 7.0 5.0 9.7 5.9 1.5 5.7 2.4 2.7 1.9 1.9 1.3 10.0 6.6 7.3 10.8 11.8 10.0 17.6 8.8 8.0 6.7 6.2 5.1 9.0 5.3 11.7 10.0 12.7 14.2 10.3 8.2 10.4 9.8 3.3 8.4 5.8 7.5 10.8 3.7 7.2 6.7 6.9 16.6 10.2 8.1 7.1 6.2 4.8 6.8 3.9 10.4 3.8 7.5 12.2 13.4 4.3 12.0 9.4 12.0 15.3 5.8 7.6 11.1 11.0 10.0 5.9 9.7 9.9 11.8 10.4 8.5 3.2 3.8 7.8 13.6 2.4 2.3 1.1 1.1 2.7 1.7 1.5 0.8 1.9 5.7 1.1 1.0 1.3 0.2 1.9 2.5 3.1 0.5 1.3 3.9 5.1 4.7 4.5 2.8 2.9 3.0 3.2 4.7 3.9 B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167868948-167874041 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "blood: 2.4;brain: 5.1;intestine: 5.8;skeletal muscle: 7.1" "Cell line enriched" "Detected in some" 8 "AN3-CA: 27.9" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.22e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-3)" "unprognostic (2.49e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-2)" "unprognostic (8.72e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-3)" "unprognostic (8.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" 0.1 0.6 0.5 0.0 1.6 0.0 0.3 0.9 5.1 0.2 5.6 0.0 0.2 0.3 0.0 0.8 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.8 0.0 0.1 5.8 0.1 0.9 7.1 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 1.4 0.8 2.0 0.5 1.0 2.4 0.4 0.0 0.0 2.2 27.9 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.6 1.0 0.0 0.1 0.0 0.4 0.0 1.8 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 0.0 0.5 0.0 2.6 2.0 0.5 0.3 0.6 0.3 0.7 1.1 0.7 0.7 0.2 1.4 2.4 1.3 1.5 1.0 0.3 0.8 0.6 0.4 B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193179045-193186654 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.9;gallbladder: 19.0;heart muscle: 25.1" "Group enriched" "Detected in some" 4 "AF22: 16.0;ASC TERT1: 7.3;LHCN-M2: 10.9;WM-115: 19.0" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "MAIT T-cell: 11.9" "Lineage enriched" "Detected in single" 57 "T-cells: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane,Microtubules" "Plasma membrane, Microtubules" "HPA078659: " "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" 0.7 2.0 11.3 1.3 8.9 0.7 0.9 1.4 32.9 0.8 1.7 1.2 0.9 1.6 0.6 1.8 1.2 0.7 19.0 25.1 10.1 7.9 1.7 0.8 2.6 0.7 5.7 19.1 13.8 0.8 0.4 0.9 0.9 5.0 6.5 2.0 0.3 0.5 7.1 0.6 0.7 4.1 0.8 6.5 1.4 2.1 1.4 4.7 0.0 1.8 0.0 1.6 2.0 0.7 0.0 0.2 0.1 0.0 0.0 11.9 0.3 0.0 0.0 16.0 0.0 0.4 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.2 0.0 11.9 0.0 2.7 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.3 0.3 11.3 8.9 1.4 32.9 10.1 7.9 5.7 19.1 5.0 4.7 B3GALT4 "beta3Gal-T4, GalT4" ENSG00000235863 "Beta-1,3-galactosyltransferase 4" O96024 6 33277132-33284832 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.1;SCLC-21H: 3.1;SK-BR-3: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043001 Approved "HPA043001: " "unprognostic (3.71e-2)" "unprognostic (1.33e-2)" "unprognostic (6.02e-2)" "unprognostic (1.00e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-2)" "unprognostic (6.00e-2)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.98e-2)" "unprognostic (1.96e-1)" "unprognostic (1.17e-3)" "unprognostic (6.83e-2)" "unprognostic (1.94e-1)" "unprognostic (1.22e-2)" "unprognostic (3.75e-2)" 7.0 6.9 3.0 9.8 4.0 3.0 6.7 5.3 6.3 7.6 9.0 6.2 13.1 8.0 6.2 7.0 14.0 6.1 9.4 5.7 3.6 3.4 7.1 1.7 6.7 11.9 3.7 3.0 3.1 3.1 5.3 4.4 7.4 4.0 6.5 4.9 6.7 9.1 15.9 2.7 10.9 12.5 4.3 4.6 11.1 7.7 19.0 2.5 14.7 5.6 5.3 9.8 8.6 7.9 7.3 4.1 12.4 8.4 6.3 9.5 5.2 0.0 0.3 0.6 0.2 0.9 1.6 0.8 0.3 0.4 0.0 0.1 0.0 5.1 0.0 0.0 0.7 2.6 0.0 0.2 0.0 2.8 0.3 0.9 0.4 0.0 1.0 0.0 2.7 2.1 1.3 0.1 0.1 0.7 0.0 0.3 0.0 0.1 1.3 1.2 0.2 0.3 0.2 0.0 0.0 0.0 0.8 3.1 0.4 0.1 5.2 0.4 0.0 1.4 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.7 12.4 6.9 10.0 9.5 6.7 7.4 6.0 5.9 8.0 4.1 7.3 5.7 5.1 7.3 6.3 8.4 3.3 6.3 5.2 3.0 4.0 5.3 6.3 3.6 3.4 3.7 3.0 4.0 2.5 B3GALT6 beta3GalT6 ENSG00000176022 "Beta-1,3-galactosyltransferase 6" Q96L58 1 1232265-1235041 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SCLC-21H: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.76e-2)" "unprognostic (6.97e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (4.62e-2)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (2.66e-1)" "unprognostic (3.08e-2)" "unprognostic (2.40e-2)" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-2)" 12.2 9.4 13.4 9.9 11.7 3.0 10.2 10.3 17.2 10.0 7.5 11.1 9.5 7.2 11.9 9.3 7.7 11.9 7.1 12.6 13.7 12.9 9.8 19.5 10.1 12.3 9.4 7.9 11.4 14.7 14.1 10.4 12.3 10.4 9.6 6.0 11.4 9.9 8.7 9.6 13.4 7.0 9.3 8.4 12.9 9.2 8.4 10.8 14.7 10.1 7.0 7.7 8.2 9.0 5.2 5.1 2.9 4.1 6.0 6.6 2.2 10.4 5.3 9.1 9.5 9.2 6.2 7.1 11.1 9.5 9.4 7.7 4.7 10.7 7.9 6.7 6.6 9.4 3.9 6.0 5.7 13.7 14.9 14.5 5.3 4.4 9.5 9.0 9.2 5.8 4.5 6.2 6.1 7.0 10.1 7.1 9.5 5.9 12.1 16.2 11.7 20.1 11.7 3.6 6.3 9.3 3.2 37.5 15.4 8.3 9.8 5.6 8.2 12.9 7.5 9.7 4.3 6.0 16.0 4.4 3.8 7.2 7.6 20.2 11.0 2.9 2.8 0.9 3.8 3.5 6.6 3.1 3.9 4.5 3.8 5.2 3.4 4.1 1.4 6.0 4.1 5.1 1.6 2.2 13.4 11.7 10.3 17.2 13.7 12.9 9.4 7.9 10.4 10.8 B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134411918 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 76.0" "Cell line enhanced" "Detected in some" "AF22: 17.0;HMC-1: 18.8;NTERA-2: 16.3;SH-SY5Y: 6.2" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 3.8;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 39 "T-cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468" Enhanced Supported Vesicles "Secreted in brain" Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" 1.5 5.8 38.9 1.7 23.7 2.1 5.6 9.2 76.0 1.7 1.5 25.8 0.0 1.8 1.6 1.7 1.4 1.6 1.7 1.5 43.4 14.9 2.1 6.0 1.8 3.3 30.3 19.5 1.5 1.7 1.4 0.9 1.4 19.7 4.2 1.5 2.1 2.2 1.8 1.4 1.8 1.6 1.5 45.1 2.1 6.0 1.8 25.2 0.0 7.7 0.0 1.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 17.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.9 0.0 0.8 1.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 16.3 0.0 0.3 0.0 1.2 0.0 0.1 2.3 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.2 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.8 1.9 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.4 38.9 23.7 9.2 33.7 43.4 14.9 30.3 19.5 19.7 25.2 B3GAT2 GlcAT-S ENSG00000112309 "Beta-1,3-glucuronyltransferase 2" Q9NPZ5 6 70856679-70957038 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 27.2" "Cell line enriched" "Detected in some" 20 "SCLC-21H: 22.2" "Group enriched" "Detected in some" 20 "glioma: 4.7;testis cancer: 1.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012059 Uncertain "HPA012059: AB_2061050" "unprognostic (7.10e-3)" "unprognostic (7.81e-2)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.96e-2)" "unprognostic (4.88e-2)" "unprognostic (4.22e-2)" "unprognostic (9.16e-4)" "unprognostic (8.09e-2)" "unprognostic (7.43e-3)" "unprognostic (6.88e-7)" "unprognostic (2.72e-2)" "unprognostic (3.35e-2)" "unprognostic (2.53e-2)" "unprognostic (3.45e-3)" 1.8 1.5 9.5 1.9 7.8 1.6 1.1 3.2 27.2 0.8 1.1 26.2 0.0 2.3 1.4 1.1 1.4 1.1 1.4 1.5 19.2 11.5 1.0 1.3 1.2 2.0 9.7 13.6 1.1 2.2 0.8 0.5 1.2 21.0 1.3 0.9 0.4 1.5 0.9 1.5 1.9 2.4 1.1 17.3 2.0 1.5 2.9 16.3 0.0 1.5 0.0 0.9 1.3 0.9 1.2 1.0 2.0 1.2 1.1 2.2 0.2 0.3 0.0 0.6 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.2 1.1 0.1 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.5 0.7 0.1 0.1 0.2 0.2 0.0 0.2 22.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.5 0.0 0.1 0.1 0.1 0.1 1.3 1.2 1.2 1.0 1.0 0.9 1.0 1.5 2.1 0.4 1.2 1.7 1.8 2.0 1.1 1.1 1.0 2.2 0.2 9.5 7.8 3.2 11.2 19.2 11.5 9.7 13.6 21.0 16.3 B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622175 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved "Intracellular and membrane" 1600000 "HPA051328: " "unprognostic (1.55e-1)" "unprognostic (3.93e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "prognostic unfavourable (4.69e-4)" "unprognostic (3.80e-2)" "prognostic unfavourable (5.11e-6)" "unprognostic (4.94e-2)" "unprognostic (2.42e-1)" "unprognostic (3.66e-2)" "unprognostic (1.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.46e-3)" "unprognostic (6.00e-2)" "unprognostic (4.48e-2)" "unprognostic (2.58e-2)" 14.4 21.6 24.8 15.9 29.2 15.0 19.7 28.9 29.1 15.4 12.9 24.2 8.1 17.6 14.9 18.8 10.6 21.1 15.3 13.1 25.8 25.6 17.4 21.5 12.8 22.9 30.0 16.8 17.0 22.4 18.5 25.6 19.9 25.7 18.2 6.8 19.0 24.9 20.9 6.4 23.1 16.5 14.2 24.4 17.5 15.5 12.0 24.8 17.5 14.5 5.4 12.9 14.4 17.4 11.2 15.7 15.7 18.9 24.5 14.1 9.4 9.7 16.1 8.8 15.3 12.1 11.9 6.5 8.1 11.5 7.7 8.7 7.1 14.5 8.6 28.1 8.2 6.3 8.9 8.1 1.7 19.2 17.2 4.1 7.4 9.0 29.2 5.8 9.7 21.2 13.8 10.1 4.2 6.8 13.7 21.7 9.1 24.8 9.9 20.8 13.6 15.1 10.1 6.3 47.4 16.0 1.9 9.3 15.3 9.3 11.0 37.1 14.8 11.5 5.3 7.9 6.1 20.9 15.6 22.7 7.6 10.0 23.9 10.5 16.4 15.7 18.4 15.5 14.1 18.3 9.3 11.2 9.8 11.4 15.7 9.1 9.8 11.4 5.4 24.5 18.9 9.3 11.7 9.4 24.8 29.2 28.9 27.7 25.8 25.6 30.0 16.8 25.7 24.8 B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196113-62224731 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles 43000000 Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" 18.9 14.3 8.6 10.8 23.0 41.6 17.5 3.1 14.1 18.4 17.9 7.4 5.6 17.9 19.8 8.0 24.5 8.7 18.1 20.9 7.6 11.5 24.4 14.2 23.9 13.9 9.7 7.1 9.0 43.2 5.4 25.9 22.8 9.5 7.5 16.3 14.4 17.2 6.0 5.2 13.0 21.7 16.3 7.6 14.6 12.0 7.0 10.6 27.0 15.6 8.5 18.5 11.8 14.7 8.4 6.8 28.3 5.6 20.3 19.3 8.2 7.6 5.3 8.1 3.5 8.9 4.0 23.3 7.5 8.3 6.0 8.0 10.9 12.4 8.3 6.9 6.9 7.4 5.1 6.3 10.4 17.3 4.1 20.5 2.5 6.4 6.7 12.2 9.2 4.9 11.9 11.5 4.1 8.9 11.1 5.2 7.2 5.8 23.2 18.3 7.7 2.2 42.6 5.6 4.5 11.4 7.5 7.8 5.8 5.3 11.5 8.6 3.3 14.4 10.1 7.3 6.4 12.2 7.4 14.8 5.2 35.9 5.7 21.2 7.0 7.2 4.5 28.3 11.0 4.4 15.6 7.6 8.2 19.3 5.5 8.4 9.9 14.4 11.3 20.3 5.6 6.8 13.2 8.2 8.6 23.0 3.1 14.1 7.6 11.5 9.7 7.1 9.5 10.6 B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813082 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 69.9;intestine: 61.6;placenta: 56.0" "Cell line enhanced" "Detected in some" "A-431: 17.8;BEWO: 17.6;CAPAN-2: 47.7;EFO-21: 12.2;RT4: 17.1;SK-BR-3: 16.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.7;memory CD8 T-cell: 1.1;naive CD4 T-cell: 3.2" "Lineage enriched" "Detected in single" 32 "T-cells: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavourable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" 0.4 0.2 0.2 8.7 0.3 0.0 1.8 0.2 0.3 3.5 25.3 0.0 12.0 16.6 0.4 1.2 15.1 0.6 69.9 0.5 0.2 0.3 11.4 2.5 1.0 1.2 0.2 0.0 0.3 9.1 0.0 0.3 56.0 0.0 4.4 22.4 0.3 24.4 12.8 0.3 2.0 61.6 1.9 0.2 0.3 21.8 0.3 0.0 0.3 0.4 2.6 18.3 10.2 5.4 0.0 0.0 0.0 0.0 0.0 3.2 0.6 17.8 4.7 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.2 47.7 0.0 12.2 0.0 1.7 0.0 5.7 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 7.7 0.0 0.0 0.4 10.6 17.1 0.0 0.0 0.0 16.2 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.1 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.2 0.3 0.2 0.3 0.2 0.0 0.0 0.0 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203543-122208952 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.3;skin 1: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 8.0;hTCEpi: 9.7;T-47d: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria Mitochondria Nucleoli "HPA055261: " "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavourable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.7 3.2 7.3 0.8 6.8 4.6 0.8 16.3 9.1 0.5 0.7 0.5 0.0 1.0 0.6 0.7 1.8 1.1 1.1 0.8 4.9 4.0 6.1 0.6 1.1 0.9 1.5 7.3 0.8 0.8 0.8 1.9 0.8 4.0 0.7 0.6 1.0 1.7 0.7 1.1 8.5 1.0 0.6 0.6 1.0 0.7 2.0 0.3 0.0 0.8 0.3 0.8 0.6 0.5 0.8 1.0 0.8 1.7 0.4 1.9 0.4 5.4 1.0 0.3 2.1 0.2 0.1 1.0 0.1 0.0 0.3 0.6 3.4 0.4 0.5 0.9 0.0 2.0 2.6 2.1 0.1 8.0 2.8 0.2 1.5 0.3 0.6 0.7 1.1 0.7 9.7 0.1 0.4 0.0 1.5 0.6 0.2 4.8 0.0 0.7 0.6 2.0 0.4 0.6 1.0 1.4 0.6 1.3 1.7 1.5 1.0 0.5 7.5 0.1 0.1 0.5 2.8 0.5 0.3 0.6 4.9 1.2 0.5 0.8 0.3 0.8 0.4 0.2 0.8 0.1 0.4 0.8 1.3 0.2 0.2 0.5 1.9 0.2 0.5 0.4 1.7 1.0 0.6 0.4 7.3 6.8 16.3 8.1 4.9 4.0 1.5 7.3 4.0 0.3 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253244-183298504 "Enzymes, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 80.2" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.8;hTCEpi: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "neutrophil: 9.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.0" "Region enriched" "Detected in single" 12 "cerebellum: 16.5" "Low region specificity" "Detected in many" HPA017292 Uncertain Approved Nucleoli Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavourable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavourable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavourable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 8.6 1.4 2.2 6.1 2.3 31.6 4.3 1.2 2.5 6.4 29.8 5.4 2.1 17.5 3.2 5.4 23.5 5.4 10.1 3.3 3.0 2.9 3.5 3.0 11.2 5.1 4.0 0.7 4.2 3.5 1.8 5.1 19.8 4.5 3.9 9.2 3.2 8.7 2.5 6.6 8.0 80.2 2.9 6.3 2.3 5.1 2.9 2.3 1.0 4.6 18.9 8.9 5.0 10.6 0.1 1.1 9.0 1.5 0.0 0.3 0.4 16.4 1.6 8.9 5.4 7.4 22.0 8.0 0.2 0.4 1.7 1.4 3.3 8.7 0.0 1.0 0.0 7.6 9.1 25.8 1.4 0.0 5.6 0.8 0.7 0.0 9.5 8.3 4.1 10.3 31.4 1.4 23.5 16.0 9.4 0.0 14.1 0.0 0.0 2.7 3.7 14.3 2.6 4.5 0.0 5.4 4.6 0.4 8.5 4.6 0.0 1.9 0.0 10.1 23.6 0.4 3.5 0.5 4.0 0.0 0.0 0.0 3.3 19.6 8.8 0.0 1.5 1.5 0.0 0.3 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.3 0.4 2.2 2.3 1.2 2.5 3.0 2.9 4.0 0.7 4.5 2.3 B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 15.8;lymphoid tissue: 17.5;stomach 1: 17.9" "Cell line enhanced" "Detected in some" "MCF7: 2.0;RPMI-8226: 1.5" "Group enriched" "Detected in some" 14 "colorectal cancer: 6.3;lung cancer: 3.9;pancreatic cancer: 5.1;prostate cancer: 5.0;stomach cancer: 4.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 2.3;neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039805 Enhanced "Intracellular and membrane" "HPA039805: " "unprognostic (1.71e-1)" "prognostic favourable (2.31e-4)" "unprognostic (4.79e-2)" "unprognostic (5.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" 0.2 0.2 0.3 6.6 0.4 0.0 0.2 0.3 0.4 0.5 15.8 0.0 0.0 3.7 0.2 0.0 2.5 0.2 0.9 0.2 0.3 0.3 0.2 0.2 1.4 0.0 0.3 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 12.4 0.0 1.6 0.0 0.2 0.2 9.4 0.0 0.2 0.2 17.9 0.6 0.0 0.0 0.2 3.4 17.5 0.2 0.3 0.4 0.3 2.3 0.2 0.8 0.5 0.2 0.1 0.0 0.5 0.5 0.0 0.2 0.2 0.1 0.2 0.5 0.1 1.1 0.2 0.7 0.3 0.0 0.0 0.1 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.6 0.2 0.5 0.4 0.0 0.0 0.0 0.2 0.6 0.0 2.0 0.2 0.5 0.7 0.0 0.0 0.1 1.5 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.1 0.3 0.4 0.5 0.3 0.1 0.2 0.2 2.3 0.2 0.3 0.4 0.2 0.5 0.2 0.2 0.2 0.0 0.4 0.3 0.3 2.2 0.8 0.0 0.3 0.1 0.2 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.0 0.0 0.0 B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623410-57633355 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4" "Cell line enhanced" "Detected in many" "EFO-21: 22.0;HDLM-2: 18.7" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.9" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" 9500 "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" 3.0 2.1 12.9 2.3 16.4 1.0 1.5 26.5 32.4 1.9 2.4 1.0 0.0 1.4 2.2 3.8 1.3 1.4 1.5 3.9 15.3 11.2 1.3 1.3 1.7 1.6 6.5 14.3 1.0 1.2 1.1 1.0 1.3 11.6 4.2 2.2 1.6 3.2 6.8 8.1 1.6 1.9 3.2 2.3 1.3 1.4 1.6 2.3 0.0 1.3 0.6 1.8 1.5 0.9 0.0 0.0 0.0 0.0 0.8 1.9 0.0 2.8 14.6 3.2 5.6 0.2 0.0 0.0 1.4 3.0 6.0 6.4 0.9 7.6 0.8 22.0 4.1 1.4 2.5 1.1 2.0 18.7 0.9 0.2 3.7 4.8 0.2 0.7 1.4 0.0 0.4 3.6 0.2 0.1 2.3 4.6 1.0 3.8 0.6 0.0 3.8 2.9 0.0 4.4 2.3 0.0 0.0 12.3 3.1 0.8 0.4 0.1 2.7 1.0 0.0 3.5 8.3 6.9 9.1 11.5 8.6 0.8 8.1 0.9 9.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 12.9 16.4 26.5 25.9 15.3 11.2 6.5 14.3 11.6 2.3 B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 460364-563509 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 43.1" "Cell line enhanced" "Detected in some" "BEWO: 25.8;HDLM-2: 9.1;HEK 293: 9.1;NTERA-2: 11.4;U-937: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favourable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" 0.3 5.7 1.4 2.1 3.8 1.5 1.1 0.3 8.2 6.1 12.8 0.6 0.4 0.8 8.5 2.9 6.0 3.4 9.6 16.8 5.6 0.9 4.1 0.3 6.2 0.2 0.9 1.7 2.1 7.9 2.5 14.7 0.1 2.0 1.6 9.8 1.5 3.8 1.1 2.7 11.0 1.7 1.9 0.5 0.4 43.1 8.0 0.1 1.0 2.1 9.1 4.1 1.8 4.0 0.0 0.0 0.7 0.1 0.0 1.4 0.0 0.0 0.0 0.2 0.9 0.0 0.0 25.8 0.0 0.0 0.0 0.0 6.4 5.0 0.0 0.6 0.0 2.8 6.4 0.7 0.0 9.1 9.1 0.0 0.0 1.3 0.0 0.0 3.8 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.4 0.5 0.4 3.5 0.0 6.2 5.5 3.1 2.0 0.6 0.2 0.7 0.6 2.0 0.0 0.0 2.0 0.2 0.6 0.0 0.1 0.1 0.0 11.1 4.3 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.4 3.8 0.3 8.2 5.6 0.9 0.9 1.7 2.0 0.1 B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369796-382116 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.1;ovary: 18.6" "Cell line enhanced" "Detected in many" "AF22: 19.7;NTERA-2: 17.6;SCLC-21H: 21.9;SH-SY5Y: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053126 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" "Intracellular and membrane" "Nucleoplasm, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA053126: " "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" 1.6 2.5 20.6 2.8 16.7 1.2 3.5 26.5 35.1 5.9 2.0 8.6 0.8 2.4 8.6 2.4 1.8 8.7 2.1 1.4 17.6 16.8 1.2 1.1 1.3 1.6 11.5 14.9 18.6 1.8 6.3 6.1 1.1 13.0 3.8 1.6 2.3 4.0 3.7 1.1 3.8 2.9 3.1 8.3 1.5 1.5 1.8 11.0 0.0 1.1 0.0 1.7 1.3 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.6 19.7 11.3 0.0 0.0 4.6 3.5 0.9 1.6 0.5 2.0 0.0 0.0 2.6 0.4 0.7 2.6 4.7 0.5 0.0 6.7 0.0 6.2 6.1 0.2 0.0 4.8 0.3 2.8 0.1 2.1 0.2 6.0 0.0 0.0 5.8 0.2 0.0 17.6 7.7 0.0 0.0 2.6 0.2 0.0 21.9 26.7 1.3 0.9 0.2 7.7 0.0 4.8 1.1 6.3 1.9 0.2 0.0 0.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.6 16.7 26.5 21.2 17.6 16.8 11.5 14.9 13.0 11.0 B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 55.7;SiHa: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 56.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" 98000000 "Golgi apparatus" "HPA010806: AB_1078255, HPA010807: AB_1078254" "unprognostic (7.57e-2)" "unprognostic (1.24e-2)" "unprognostic (2.09e-1)" "prognostic favourable (6.85e-7)" "unprognostic (1.83e-2)" "unprognostic (9.94e-2)" "unprognostic (3.08e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-3)" "unprognostic (2.78e-1)" "unprognostic (7.93e-3)" "unprognostic (4.98e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.46e-2)" 32.0 19.5 4.5 22.5 4.5 22.1 35.1 5.9 3.5 25.4 20.4 6.4 29.1 6.5 19.5 34.1 24.7 26.3 24.2 33.1 3.2 2.5 31.7 91.2 34.9 44.9 5.8 2.2 56.8 20.1 30.2 11.9 79.0 5.9 22.6 11.1 32.1 39.1 42.7 15.0 17.6 18.9 17.7 6.4 38.5 19.9 37.6 3.6 23.1 39.3 16.9 41.0 26.4 21.6 24.8 56.4 24.9 9.1 18.2 16.5 5.4 15.9 11.8 2.2 3.0 11.2 19.8 39.9 16.6 20.9 10.0 10.0 7.2 18.6 6.1 10.6 24.2 8.6 2.2 20.6 10.1 55.7 2.2 3.5 49.2 5.5 22.1 2.8 5.9 22.1 36.9 11.4 14.0 10.6 3.9 7.6 9.5 13.9 2.5 5.7 1.3 3.6 3.4 2.0 4.0 30.1 13.9 1.6 2.1 105.0 20.5 4.1 25.9 5.2 9.8 7.2 8.5 23.1 6.4 1.2 2.8 3.8 22.3 3.9 2.6 6.2 9.1 5.0 13.0 7.8 16.5 24.8 8.7 11.4 6.1 20.7 5.3 6.7 24.9 18.2 6.0 56.4 5.7 5.4 4.5 4.5 5.9 3.5 3.2 2.5 5.8 2.2 5.9 3.6 B4GALT2 beta4Gal-T2 ENSG00000117411 "Beta-1,4-galactosyltransferase 2" O60909 1 43978943-43991170 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007620, HPA047739" Supported Supported "Golgi apparatus,Vesicles" 12000 "Golgi apparatus, Vesicles" "HPA007620: , HPA047739: " "unprognostic (1.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-1)" "unprognostic (7.59e-2)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "prognostic unfavourable (2.96e-5)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (4.23e-3)" "unprognostic (7.58e-2)" "prognostic unfavourable (3.62e-5)" "unprognostic (6.54e-2)" "unprognostic (1.52e-1)" "unprognostic (7.66e-2)" "unprognostic (3.12e-3)" 18.6 8.6 34.5 10.1 22.4 4.6 15.6 8.1 35.7 18.4 16.1 16.1 10.7 9.4 13.3 8.5 20.2 11.4 11.9 23.3 25.3 18.9 8.4 24.2 7.7 4.4 18.9 15.6 15.3 39.5 9.9 10.6 9.9 12.7 13.5 10.4 8.7 21.4 21.5 41.0 19.5 9.4 21.3 16.1 5.2 11.2 11.4 11.3 1.9 9.0 12.1 10.1 16.5 11.7 1.7 0.4 0.1 0.6 0.2 2.6 0.7 19.8 14.5 15.2 25.8 20.6 18.5 15.2 22.6 18.6 18.0 16.5 9.5 17.6 13.1 11.5 36.0 13.8 13.5 23.1 8.4 13.2 25.7 8.7 10.1 21.8 16.7 8.3 0.3 16.1 27.0 12.9 26.4 20.8 16.4 8.5 14.0 14.3 4.3 8.3 21.1 18.2 15.6 20.4 20.5 12.7 9.3 27.6 22.9 9.9 31.2 15.1 13.6 9.9 16.3 31.3 40.2 21.6 25.1 3.0 5.9 5.6 14.0 6.3 20.9 0.0 0.2 0.0 2.6 0.6 2.4 1.7 1.2 2.2 0.4 0.5 0.0 2.0 0.1 0.2 0.1 0.2 1.1 0.7 34.5 22.4 8.1 35.7 25.3 18.9 18.9 15.6 12.7 11.3 B4GALT3 beta4Gal-T3 ENSG00000158850 "Beta-1,4-galactosyltransferase 3" O60512 1 161171310-161177968 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010793 Approved Supported "Golgi apparatus,Cytosol" 74000 "Golgi apparatus" Cytosol "HPA010793: AB_1078256" "unprognostic (5.67e-3)" "unprognostic (7.68e-3)" "unprognostic (1.20e-2)" "unprognostic (8.15e-3)" "unprognostic (3.91e-1)" "unprognostic (1.10e-2)" "prognostic unfavourable (5.87e-5)" "unprognostic (3.11e-2)" "unprognostic (3.13e-1)" "unprognostic (4.64e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-1)" "prognostic unfavourable (7.12e-7)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" 20.7 18.7 16.5 17.2 22.1 17.3 33.4 20.1 23.2 15.0 19.0 12.4 22.2 18.4 13.6 21.0 20.4 17.2 17.5 17.2 13.4 14.7 22.5 21.7 20.8 21.6 16.4 13.4 25.4 37.5 15.8 29.1 41.0 16.6 18.5 19.3 14.8 33.0 27.8 19.5 20.2 15.1 11.7 14.1 26.6 21.5 28.4 16.4 14.8 28.2 10.7 21.4 20.6 22.9 16.7 22.6 7.1 12.6 15.1 25.5 11.9 9.7 6.5 9.6 12.7 14.3 7.3 15.3 5.6 10.0 11.6 10.7 12.7 19.9 9.0 16.0 6.2 9.9 10.1 6.2 6.9 9.4 12.3 5.1 4.3 10.2 10.3 10.1 14.4 10.2 9.2 10.7 11.6 13.1 16.6 20.3 9.4 10.1 6.6 9.7 12.0 13.8 8.0 5.4 22.2 9.8 6.0 13.7 16.2 5.6 14.8 11.7 14.8 18.5 5.5 5.8 10.5 6.5 16.2 73.3 39.5 12.0 8.6 8.7 9.2 5.1 8.9 7.1 17.6 10.1 15.7 16.7 16.7 16.8 10.8 13.5 16.4 15.4 5.9 15.1 12.6 22.6 25.5 11.9 16.5 22.1 20.1 23.2 13.4 14.7 16.4 13.4 16.6 16.4 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119241103 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: " "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavourable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 9.6 7.7 7.0 8.6 8.5 11.6 8.8 5.3 6.6 10.1 20.8 8.2 12.6 14.6 15.1 43.4 13.2 12.6 21.3 11.1 6.0 6.2 15.0 11.8 8.9 8.0 7.7 7.3 13.5 20.8 8.5 16.2 23.7 9.1 9.4 17.9 10.2 10.1 16.1 4.8 10.9 40.4 11.3 9.3 8.2 16.8 5.8 6.5 8.5 10.8 6.5 11.4 13.0 8.7 3.7 4.7 11.2 4.6 11.7 12.2 4.8 17.3 33.6 3.9 2.8 12.2 10.2 20.0 38.0 16.8 17.7 17.8 19.8 5.6 3.8 8.0 19.9 23.8 6.6 5.1 17.9 7.3 2.3 5.1 5.6 10.5 8.4 3.0 4.6 7.3 7.1 7.6 6.0 1.7 3.5 3.9 7.3 6.5 1.4 2.6 5.1 9.1 1.4 3.6 1.4 9.7 19.0 3.4 8.0 9.1 4.0 8.2 8.7 1.4 1.2 8.4 7.7 4.2 4.2 8.8 6.9 4.9 7.0 2.8 7.0 11.2 3.7 6.8 12.2 4.6 6.9 3.7 6.0 6.4 4.7 2.9 11.3 6.8 2.2 11.7 4.0 3.1 2.3 4.8 7.0 8.5 5.3 6.6 6.0 6.2 7.7 7.3 9.1 6.5 B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622247-31685836 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.3" "Cell line enhanced" "Detected in many" "REH: 18.1;WM-115: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 3.8" "Group enriched" "Detected in many" 5 "NK-cells: 3.8;T-cells: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved "Intracellular and membrane" "CAB020701: , HPA058284: " "unprognostic (3.79e-1)" "unprognostic (4.52e-1)" "unprognostic (6.54e-3)" "unprognostic (2.23e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-2)" "unprognostic (4.50e-2)" "unprognostic (5.18e-1)" "unprognostic (1.13e-1)" "prognostic favourable (5.65e-4)" "unprognostic (2.77e-1)" "prognostic favourable (6.40e-5)" "unprognostic (5.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" 3.6 13.8 7.8 2.8 16.0 4.4 2.1 20.6 22.3 2.2 3.5 2.6 0.0 7.7 2.5 2.2 4.8 2.5 7.2 3.8 10.7 7.9 3.7 2.7 1.8 1.2 6.1 10.0 4.3 2.1 7.3 14.8 2.7 16.3 5.8 3.6 13.2 4.6 4.4 3.3 2.2 9.7 1.7 3.1 1.5 3.4 5.4 2.3 5.0 2.1 1.5 1.0 3.6 2.1 0.0 0.5 0.0 0.4 3.8 1.1 0.3 2.3 5.3 9.5 5.3 0.1 0.2 3.5 0.7 0.0 0.1 0.0 9.8 2.0 3.6 4.4 0.9 0.9 5.0 4.2 0.6 14.3 4.4 4.8 0.5 0.2 1.1 8.6 0.8 1.0 0.9 1.4 3.0 5.2 0.7 0.0 0.0 1.4 9.6 0.6 4.1 2.9 18.1 1.6 0.0 1.1 4.8 5.1 7.9 3.4 0.6 6.2 0.6 2.6 5.2 10.8 2.2 0.0 5.8 3.6 0.2 7.5 4.4 7.9 50.1 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.1 0.9 0.5 0.0 0.0 1.1 0.0 3.8 0.4 0.0 0.0 0.3 7.8 16.0 20.6 22.3 10.7 7.9 6.1 10.0 16.3 2.3 B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600100-177610347 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported "HPA042330: AB_10796576" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (5.97e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (9.53e-2)" "unprognostic (4.19e-3)" "unprognostic (3.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-3)" "unprognostic (2.00e-2)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" 13.8 33.0 16.0 20.4 14.3 20.7 19.1 10.6 19.6 13.3 12.4 14.9 20.4 16.1 15.5 15.9 11.7 13.3 20.3 17.3 13.7 18.0 16.2 21.3 12.0 21.5 15.1 17.9 16.9 37.0 15.5 23.9 15.3 14.3 16.4 11.7 14.7 22.4 20.9 14.4 12.9 13.7 12.2 10.8 16.3 16.2 16.1 11.7 10.4 16.7 9.8 18.6 13.0 10.2 15.8 16.3 11.2 16.1 8.5 12.5 9.0 8.5 15.1 6.4 15.9 12.7 9.6 28.7 13.3 14.1 12.1 13.9 14.3 13.6 11.0 24.6 13.5 10.2 4.3 28.5 5.3 36.7 11.5 5.8 11.8 9.9 18.4 6.0 10.1 14.6 10.1 13.0 10.6 13.4 5.0 10.6 12.3 19.9 5.0 7.3 6.2 22.3 10.4 4.6 12.0 9.2 13.0 5.6 6.5 6.6 13.4 11.7 8.6 7.0 10.3 15.5 8.9 10.1 13.1 13.3 6.1 7.8 13.1 14.4 14.0 11.2 14.6 7.8 12.5 16.1 11.3 12.8 11.6 11.0 16.3 15.8 10.5 10.3 1.0 8.5 15.3 12.8 7.5 9.0 16.0 14.3 10.6 19.6 13.7 18.0 15.1 17.9 14.3 11.7 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101360417-101383519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 128.4" "Cell line enhanced" "Detected in some" "A549: 6.1;CACO-2: 3.4;Hep G2: 2.4" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles 470000 Vesicles "HPA021251: AB_1845247, HPA021330: " "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favourable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.0 0.1 0.1 0.2 128.4 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.1 0.1 6.1 0.4 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.3 3.4 0.1 0.6 0.2 0.0 0.3 0.1 0.2 0.5 0.3 0.1 0.5 0.2 2.4 0.0 0.9 0.3 0.0 1.0 0.1 0.0 0.0 0.7 0.4 0.5 0.1 0.2 0.3 1.0 0.7 0.2 1.1 0.2 0.6 0.2 0.3 0.4 0.4 0.2 0.5 0.0 0.2 0.1 0.6 0.6 0.2 0.4 0.4 0.6 0.5 0.5 0.2 0.6 0.3 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: , HPA044864: " "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 4.4 1.9 3.2 11.8 4.8 16.1 4.9 1.2 5.8 7.3 5.4 5.4 3.6 3.7 6.8 5.0 10.0 4.1 3.9 3.6 3.4 2.8 2.2 2.1 5.3 8.2 5.1 1.9 5.8 3.7 3.6 6.3 3.8 4.5 5.7 6.1 1.9 4.7 6.5 12.4 16.3 4.5 7.5 5.3 4.7 3.8 9.5 3.9 25.8 4.0 8.0 9.9 8.3 7.8 9.7 6.6 6.0 3.4 6.1 16.0 2.0 7.7 4.3 11.7 6.0 1.6 2.0 8.0 9.4 5.5 9.3 10.7 5.4 7.7 8.3 4.5 3.9 8.5 8.4 5.5 13.3 6.6 4.4 8.3 7.9 5.7 0.6 9.2 8.4 2.7 0.8 8.2 4.5 3.1 4.6 23.5 8.9 6.4 16.5 9.6 9.2 2.2 14.3 11.8 7.5 2.7 6.5 3.7 5.9 8.6 9.9 3.4 10.2 9.2 2.7 12.0 8.4 7.0 8.5 7.1 7.9 16.9 4.8 7.0 8.0 2.9 1.7 6.0 4.8 3.4 3.1 8.9 5.3 5.2 3.0 9.7 2.5 3.6 0.5 6.1 2.9 6.6 16.0 2.0 3.2 4.8 1.2 5.8 3.4 2.8 5.1 1.9 4.5 3.9 BAZ1B "WBSCR10, WBSCR9, WSTF" ENSG00000009954 "Bromodomain adjacent to zinc finger domain 1B" Q9UIG0 7 73440398-73522278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037081, CAB037158, HPA067010" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037081: AB_477637, CAB037158: AB_477636, HPA067010: " "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (1.37e-1)" "unprognostic (5.72e-2)" "unprognostic (1.10e-3)" "unprognostic (1.89e-1)" "unprognostic (1.09e-1)" "unprognostic (2.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 23.3 22.3 21.4 26.4 23.9 20.7 24.6 32.4 23.4 24.6 24.2 21.1 34.1 15.3 26.3 19.8 18.1 20.6 16.5 19.8 22.4 21.4 17.1 23.4 19.4 24.7 29.3 19.4 31.8 20.2 34.9 27.0 23.1 22.3 23.1 20.5 16.4 18.0 30.8 28.9 14.6 19.2 28.7 22.9 22.2 18.8 16.2 27.3 46.5 23.5 17.9 27.7 24.7 24.4 5.3 6.2 6.1 3.1 5.6 6.3 1.7 20.6 21.3 29.4 32.8 15.2 16.3 9.8 20.1 15.5 19.4 20.5 17.3 15.7 39.1 4.7 17.9 14.6 35.7 13.4 29.3 22.0 18.1 23.3 25.3 14.9 17.0 35.1 19.7 11.6 13.1 23.9 29.5 15.4 40.5 24.6 21.7 19.6 35.9 16.2 19.0 16.0 36.6 25.8 26.0 11.0 16.3 29.5 25.2 28.7 32.1 16.8 19.7 17.6 18.0 33.7 19.4 20.2 34.2 14.3 22.7 67.1 19.1 33.3 30.5 6.1 3.1 1.9 6.3 2.2 5.5 2.5 4.8 4.6 2.1 5.3 3.8 4.1 2.2 5.6 1.7 6.2 4.7 1.7 21.4 23.9 32.4 23.4 22.4 21.4 29.3 19.4 22.3 27.3 BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810022-24949459 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 52.7" "Cell line enhanced" "Detected in many" "HDLM-2: 51.1;NTERA-2: 58.7;RH-30: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 14.7" "Group enriched" "Detected in many" 9 "dendritic cells: 5.4;monocytes: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain 85000 "HPA048592: " "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavourable (1.38e-4)" "prognostic unfavourable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavourable (8.54e-4)" 12.5 6.1 5.2 6.9 5.7 2.6 6.3 1.3 7.8 4.3 3.0 2.6 0.0 1.4 8.6 3.9 2.9 7.8 4.7 2.4 4.7 7.9 1.8 1.8 13.8 7.4 11.3 2.9 8.3 52.7 1.1 19.1 14.0 18.5 2.0 3.1 12.3 4.4 1.4 1.3 1.2 3.8 5.9 6.3 2.4 2.4 7.3 2.0 7.1 1.7 0.7 5.3 4.3 6.3 1.1 5.4 1.0 14.7 0.0 0.2 0.8 5.9 2.4 22.1 0.0 6.4 12.5 11.4 12.2 8.2 6.9 11.6 13.4 16.9 22.2 0.0 20.3 2.4 15.8 0.1 18.6 51.1 3.1 18.0 0.4 7.2 23.2 20.4 6.6 16.2 0.4 17.6 3.7 23.3 17.3 0.2 5.8 0.1 12.8 5.7 58.7 1.6 0.0 64.1 0.2 0.0 2.1 0.0 12.1 0.0 0.0 0.1 0.0 8.8 30.6 4.1 15.5 16.5 11.4 2.7 2.6 30.9 14.5 12.3 0.0 0.0 2.1 0.0 0.0 3.4 0.1 1.1 0.0 0.1 5.4 0.0 0.0 0.0 1.0 0.0 14.7 3.3 0.2 0.8 5.2 5.7 1.3 7.4 4.7 7.9 11.3 2.9 18.5 2.0 BCAT2 "BCAM, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Supported Mitochondria 3400000 Mitochondria "HPA054091: " "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (2.98e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.68e-5)" "unprognostic (1.87e-3)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (7.50e-3)" 11.8 34.1 6.7 10.9 7.7 3.8 15.0 15.0 10.7 11.9 16.7 11.3 15.8 10.2 12.9 9.8 24.6 11.9 15.2 25.1 6.8 6.9 22.6 8.0 19.9 16.3 9.8 7.8 22.3 42.6 9.0 12.3 27.5 22.0 16.8 12.1 6.3 24.7 17.2 23.3 9.8 10.3 17.5 7.6 10.9 22.8 15.9 10.7 12.5 19.1 23.3 16.7 29.2 12.2 15.0 18.2 1.8 9.8 8.8 15.4 7.1 17.4 21.0 5.6 11.8 23.3 7.9 9.9 7.7 3.9 9.5 9.3 21.0 10.7 20.5 8.9 6.9 8.3 8.6 13.5 4.8 12.8 21.7 7.5 9.4 1.3 22.6 10.1 7.1 11.4 8.6 7.1 10.3 13.2 9.6 12.7 3.4 20.8 13.8 10.8 4.9 10.2 21.1 9.6 22.6 9.0 72.2 30.1 8.6 11.8 19.4 5.7 12.3 5.0 7.3 9.3 9.0 10.9 9.6 11.9 15.8 9.8 5.0 15.8 6.0 0.0 8.7 1.8 9.7 9.8 13.6 15.0 11.7 12.4 16.1 12.8 10.8 9.6 0.4 8.8 3.7 18.2 15.4 7.1 6.7 7.7 15.0 10.7 6.8 6.9 9.8 7.8 22.0 10.7 BCKDK ENSG00000103507 "Branched chain ketoacid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 26.8;granulocytes: 26.6;monocytes: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria Mitochondria "HPA017995: AB_1845309, HPA056067: " "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 15.4 29.7 11.9 13.1 15.0 9.4 18.3 18.8 21.3 11.7 14.1 9.6 19.9 11.2 14.8 14.9 14.9 13.8 15.1 39.2 14.2 10.3 21.3 46.5 18.2 32.5 10.7 17.3 15.1 52.4 17.4 8.9 11.4 13.2 14.9 9.9 10.4 33.9 25.7 67.7 21.5 12.2 19.9 15.6 16.0 19.9 11.2 9.3 8.0 11.7 25.9 10.6 15.3 12.0 6.9 26.8 26.6 33.0 6.3 6.8 13.6 18.1 20.4 11.5 17.3 14.2 14.3 12.5 15.8 19.5 24.6 24.1 13.3 12.1 17.0 23.0 19.7 12.6 8.1 27.5 15.9 13.7 25.3 18.4 13.9 24.2 25.1 9.5 16.9 21.0 11.1 21.1 17.6 26.2 9.3 16.1 36.8 30.9 8.8 12.6 9.8 16.5 17.8 16.8 31.3 18.8 12.5 17.8 16.3 12.3 30.3 9.8 18.2 9.2 16.8 18.8 10.9 19.2 13.1 16.8 6.0 6.0 21.3 13.8 17.6 12.2 33.0 23.1 5.7 27.4 5.6 6.9 5.2 4.2 26.8 5.4 4.4 5.0 26.6 6.3 19.3 5.8 6.8 13.6 11.9 15.0 18.8 21.3 14.2 10.3 10.7 17.3 13.2 9.3 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR, RhoGEF and GTPase activating protein" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favourable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 14.5 8.4 24.0 9.1 41.2 26.7 10.5 14.2 26.5 13.6 9.7 10.3 10.6 8.7 9.2 13.9 19.3 10.8 8.3 7.8 20.9 13.0 16.3 8.3 11.3 10.9 16.0 15.6 8.8 12.9 14.5 14.9 15.7 14.2 7.0 6.8 8.3 15.5 9.7 3.4 12.8 8.7 9.0 9.5 9.1 14.0 9.6 15.4 11.8 16.6 5.5 9.2 9.2 8.8 1.5 0.8 1.2 1.0 2.8 6.6 2.5 18.6 8.1 12.4 12.7 7.4 5.1 18.8 6.8 6.3 6.3 5.1 14.1 7.5 13.0 12.6 5.7 19.2 1.3 18.8 1.8 24.9 12.9 11.4 11.1 11.2 9.7 10.5 6.0 4.3 12.7 9.4 8.2 21.8 43.5 6.1 2.8 12.3 9.8 8.2 10.5 7.9 12.9 5.0 8.6 9.7 11.8 11.4 10.8 12.4 10.7 5.1 6.7 8.6 24.6 3.8 0.4 6.1 5.5 1.4 5.6 4.6 9.7 8.0 5.8 0.0 1.0 0.0 6.6 0.4 2.3 1.4 3.3 3.3 0.8 1.5 2.6 3.6 1.2 2.8 1.0 0.8 1.6 2.5 24.0 41.2 14.2 24.9 20.9 13.0 16.0 15.6 14.2 15.4 BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111779-79132290 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 105.9;liver: 216.2" "Cell line enhanced" "Detected in some" "Hep G2: 8.2;NTERA-2: 3.5;SCLC-21H: 2.2" "Cancer enhanced" "Detected in some" "liver cancer: 90.6;renal cancer: 50.4" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038285, HPA058310" Enhanced Supported Cytosol 9200000 Cytosol "HPA038285: AB_10675791, HPA058310: AB_2683675" "unprognostic (2.61e-2)" "unprognostic (4.12e-1)" "unprognostic (4.45e-1)" "unprognostic (4.14e-3)" "unprognostic (5.62e-2)" "unprognostic (4.14e-1)" "prognostic favourable (7.32e-4)" "unprognostic (5.33e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (9.66e-4)" "unprognostic (6.42e-2)" "unprognostic (8.26e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.30e-3)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.1 1.5 0.0 105.9 216.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 4.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 8.2 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 3.5 0.0 0.0 1.2 0.0 0.0 0.0 2.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.5 0.0 0.0 0.6 0.1 0.0 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069717-79089466 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 87.9;liver: 122.9" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.9;Hep G2: 37.2;hTEC/SVTERT24-B: 22.8;U-87 MG: 9.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044573 Enhanced 1400000 "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 9.3 4.4 1.7 0.9 2.0 0.2 8.2 1.1 1.0 1.7 3.4 1.1 2.9 0.6 3.2 10.5 3.5 1.4 2.9 3.3 1.5 1.5 87.9 122.9 0.6 0.4 1.6 1.0 1.9 0.5 0.5 3.2 0.3 3.5 3.0 0.8 8.2 0.8 4.0 2.2 0.4 1.3 10.5 2.2 0.3 2.4 1.4 0.9 0.0 4.6 1.9 0.4 6.4 4.4 0.9 0.5 3.2 0.4 2.4 0.7 0.3 0.0 0.0 0.0 0.0 4.3 3.1 1.4 3.7 8.9 2.1 4.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.1 37.2 3.4 0.2 0.0 3.8 0.0 22.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 0.2 0.0 2.5 0.4 0.7 0.4 0.3 0.5 0.5 0.6 0.4 0.2 0.9 0.6 0.7 3.2 2.4 0.2 0.5 0.4 0.3 1.7 2.0 1.1 1.0 1.5 1.5 1.6 1.0 3.5 0.9 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 20.9 25.8 19.1 23.3 24.1 25.9 57.0 20.5 28.5 25.1 22.2 18.4 18.7 19.3 24.6 31.1 18.6 17.0 21.1 39.2 19.1 18.3 24.3 36.8 34.0 47.2 23.3 15.8 21.5 40.8 22.0 27.3 24.3 22.3 19.6 22.2 14.3 21.9 22.1 38.8 17.3 24.4 23.8 26.3 27.6 19.0 19.7 15.5 51.2 18.9 17.3 21.9 22.2 20.2 5.8 12.6 37.5 16.6 12.2 12.0 9.8 9.6 7.2 11.1 8.7 14.1 19.5 7.1 37.5 14.4 21.5 13.1 8.9 24.1 10.6 37.2 17.2 10.7 7.2 9.9 25.9 14.2 3.7 10.7 5.3 10.8 14.4 6.4 6.9 12.4 19.3 12.3 15.8 14.7 9.6 0.0 38.7 3.1 6.8 5.7 5.3 7.0 3.4 14.4 7.1 16.6 11.2 4.6 6.1 13.1 8.0 11.2 12.6 7.8 24.1 45.6 10.3 13.7 24.2 4.4 6.0 7.3 9.8 8.2 33.2 31.7 16.6 37.5 9.1 15.2 7.5 5.8 8.7 8.4 12.6 5.6 11.3 11.3 25.5 12.2 16.3 7.6 12.0 9.8 19.1 24.1 20.5 28.5 19.1 18.3 23.3 15.8 22.3 15.5 BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 46.0;lymphoid tissue: 46.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.5;Daudi: 33.0;HDLM-2: 31.2;hTERT-HME1: 32.8;U-266/70: 22.0;U-266/84: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 32.9;naive B-cell: 32.9" "Group enriched" "Detected in many" 10 "B-cells: 32.9;T-cells: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favourable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favourable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavourable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavourable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavourable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" 6.9 3.3 1.4 43.9 2.3 5.1 5.4 0.5 2.0 5.3 13.1 0.5 2.8 6.8 2.9 3.7 8.4 3.9 13.9 6.0 2.2 1.3 10.8 12.5 21.8 46.3 2.8 1.2 3.4 7.0 1.1 14.5 0.9 2.2 8.7 6.2 1.1 9.2 4.7 2.2 5.5 46.0 7.3 3.0 34.9 15.9 3.2 2.7 34.2 3.0 4.1 34.0 12.6 6.2 32.9 0.8 2.0 2.6 2.5 17.1 2.8 6.3 5.1 0.0 0.1 0.1 0.7 0.6 0.5 4.3 0.6 0.7 0.9 37.5 33.0 17.0 0.3 3.6 0.0 0.9 2.1 31.2 0.1 0.1 1.5 0.2 6.5 0.5 0.7 0.7 4.6 2.1 32.8 0.1 0.1 0.0 0.8 0.0 2.2 0.3 0.1 0.2 0.0 0.3 1.6 8.5 3.3 0.0 0.1 0.5 0.5 0.3 1.6 0.3 1.7 7.2 0.7 0.4 6.5 22.0 18.8 11.6 1.3 1.8 0.8 2.0 0.9 0.4 1.4 2.2 2.5 32.9 10.7 3.5 0.8 32.9 7.5 2.2 0.5 2.5 2.6 0.3 17.1 2.8 1.4 2.3 0.5 2.0 2.2 1.3 2.8 1.2 2.2 2.7 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Supported "Golgi apparatus,Vesicles,Mitotic spindle" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: " "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 15.0 16.7 10.3 20.7 14.4 18.4 16.1 21.9 13.7 16.2 13.0 15.3 15.6 8.7 17.2 13.9 13.2 13.1 11.7 11.4 9.8 7.3 14.1 14.8 12.5 16.1 13.9 11.8 23.6 24.8 32.5 17.4 14.1 14.8 11.3 13.6 11.5 14.7 17.1 20.9 14.9 16.0 12.5 13.3 16.1 13.9 13.0 14.4 23.1 21.5 9.2 17.2 16.2 12.0 3.8 2.8 10.6 2.4 2.3 3.4 0.7 15.1 12.7 11.8 5.1 9.3 13.2 7.1 6.7 9.5 8.3 7.9 8.7 3.6 16.3 5.4 12.6 7.0 16.5 10.0 10.3 13.0 7.5 22.0 8.0 7.2 5.1 20.4 7.8 8.8 4.9 13.0 11.6 12.3 17.8 7.0 7.7 5.8 10.2 4.7 7.9 7.5 10.4 19.0 5.5 6.0 15.6 8.8 13.5 13.3 6.9 6.1 4.6 7.3 19.2 8.7 9.8 5.9 10.2 9.4 13.1 21.8 6.3 10.1 5.7 10.6 1.6 0.9 2.7 1.2 3.4 1.7 2.1 2.3 1.3 3.8 2.3 2.6 2.7 2.3 2.4 2.8 1.6 0.7 10.3 14.4 21.9 13.7 9.8 7.3 13.9 11.8 14.8 14.4 BIRC7 "KIAP, ML-IAP, mliap, RNF50" ENSG00000101197 "Baculoviral IAP repeat containing 7" Q96CA5 20 63235883-63240507 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 14.4;placenta: 13.6;retina: 21.1" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 62.2" "Cancer enriched" "Detected in many" 10 "melanoma: 73.7" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 9 "T-cells: 2.0" "Not detected" "Not detected" "HPA047850, HPA061283" Enhanced Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA047850: , HPA061283: " "unprognostic (3.60e-1)" "unprognostic (7.94e-2)" "unprognostic (2.70e-2)" "unprognostic (1.78e-3)" "unprognostic (1.15e-1)" "unprognostic (8.11e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.62e-3)" "unprognostic (1.24e-2)" "unprognostic (6.90e-2)" "unprognostic (2.27e-1)" "unprognostic (8.82e-3)" "unprognostic (1.22e-2)" "unprognostic (4.77e-2)" "unprognostic (2.55e-2)" "unprognostic (4.84e-2)" 1.6 1.3 1.0 0.7 1.0 0.3 0.7 0.1 2.2 3.0 1.3 0.5 0.1 0.4 0.8 14.4 0.3 0.3 0.5 2.8 0.9 1.1 2.6 0.8 2.3 2.2 4.9 1.0 0.2 0.1 0.1 0.6 13.6 1.5 0.4 0.3 21.1 0.8 0.1 0.1 4.9 0.3 0.2 4.3 1.6 0.3 0.4 0.3 0.3 0.3 1.0 0.5 0.4 1.8 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.1 0.4 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 0.2 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 62.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.0 0.1 2.2 0.9 1.1 4.9 1.0 1.5 0.3 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564604 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "blood: 47.8;intestine: 23.5;lymphoid tissue: 39.8" "Cell line enhanced" "Detected in some" "Daudi: 43.0;REH: 11.6;RPMI-8226: 14.2;U-698: 21.0;U-87 MG: 8.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 47.8;naive B-cell: 33.9" "Lineage enriched" "Detected in many" 5 "B-cells: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005093, HPA069571" Approved Approved Nucleoplasm Nucleoplasm "CAB005093: AB_2274756, HPA069571: " "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.2 0.1 32.3 0.1 1.7 0.2 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.0 1.9 0.2 0.4 0.3 0.1 0.1 1.3 0.5 0.6 27.6 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.3 2.4 0.0 0.1 0.1 23.5 0.0 0.1 31.9 1.4 0.2 0.0 3.9 0.7 0.4 39.8 2.5 0.4 47.8 4.3 0.1 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.6 0.0 14.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 3.7 21.0 8.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 9.8 47.8 0.3 1.1 0.0 33.9 0.2 0.1 0.1 0.0 0.0 4.3 0.4 1.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916372 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 37.9;HMC-1: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favourable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 11.4 11.1 15.6 18.6 15.0 15.3 12.0 8.2 12.7 11.1 13.9 20.3 2.1 8.0 11.3 9.6 15.7 10.0 12.3 17.0 18.0 9.5 8.3 10.2 14.1 22.9 20.9 12.0 6.5 6.4 7.7 7.8 14.4 14.5 8.4 18.9 11.4 10.2 6.0 7.5 14.5 15.9 10.4 28.3 19.2 7.4 19.6 16.5 19.9 12.5 5.9 24.4 9.7 12.8 2.7 1.7 3.8 2.6 0.4 0.4 0.5 5.4 2.0 3.0 3.9 5.9 5.6 2.3 5.2 8.1 5.9 7.7 3.7 2.9 6.6 2.7 25.2 1.3 3.5 4.2 10.8 1.8 1.2 37.9 2.4 1.7 6.5 7.9 41.1 8.2 5.5 9.2 8.5 7.9 10.2 19.0 6.9 1.1 4.7 3.3 1.4 1.3 6.8 5.4 1.6 7.2 2.9 4.7 2.5 7.6 3.9 4.6 1.4 4.1 7.7 5.8 2.3 9.6 5.6 3.5 1.4 2.5 5.1 9.9 4.0 0.4 2.2 1.2 0.1 0.9 0.1 2.7 0.1 0.0 1.7 2.7 0.4 0.2 3.8 0.4 2.6 1.3 0.0 0.5 15.6 15.0 8.2 12.7 18.0 9.5 20.9 12.0 14.5 16.5 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932838 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavourable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 8.9 7.0 9.4 7.9 12.4 0.9 10.7 14.1 9.2 19.4 20.6 10.9 7.7 6.2 16.3 12.3 8.4 10.9 10.8 11.0 7.7 6.1 8.2 4.6 7.4 2.9 7.3 7.6 16.1 10.6 10.0 14.0 7.4 8.5 12.8 9.3 10.9 12.6 14.2 8.4 11.3 9.8 16.5 12.2 3.4 12.1 7.8 9.2 0.3 19.4 7.8 5.7 16.0 11.4 1.8 1.1 3.6 0.8 0.9 1.4 0.3 7.5 3.8 14.7 12.5 7.7 5.0 2.6 7.6 8.0 4.5 5.2 6.5 6.7 2.3 3.5 9.7 8.1 6.5 8.3 6.6 2.5 3.7 2.9 3.6 10.7 4.1 4.0 20.4 4.4 3.5 6.0 4.4 0.0 4.5 1.6 5.2 3.2 2.6 3.2 8.0 1.8 0.0 5.8 0.0 9.2 7.2 1.5 4.8 8.5 4.3 5.1 7.3 2.0 3.8 3.2 5.2 6.6 7.0 0.4 7.0 2.9 2.8 2.7 2.6 2.0 0.8 0.6 1.4 0.5 0.9 1.8 1.4 1.2 0.3 1.5 1.0 1.1 3.6 0.9 0.6 1.1 0.7 0.3 9.4 12.4 14.1 9.2 7.7 6.1 7.3 7.6 8.5 9.2 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757968-95158448 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 28.0;ductus deferens: 25.1;prostate: 25.3;seminal vesicle: 32.0" "Cell line enhanced" "Detected in many" "A549: 18.3;MCF7: 9.2;SH-SY5Y: 15.3" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favourable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 1.1 5.6 12.7 0.8 15.0 0.7 1.7 11.6 12.7 28.0 1.2 5.5 25.1 0.7 5.3 3.2 1.1 14.3 3.4 1.3 13.4 5.9 9.3 1.4 2.4 0.5 5.4 8.6 7.6 1.7 0.6 2.4 1.2 12.1 25.3 0.8 0.7 1.4 32.0 3.3 1.4 0.6 1.2 7.5 1.4 2.8 4.3 11.2 10.8 0.8 0.1 0.6 0.7 0.7 0.4 0.5 1.9 0.9 0.8 1.6 0.3 0.0 18.3 4.9 0.0 1.9 4.5 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.8 1.0 2.9 6.7 0.0 0.0 4.5 0.0 1.1 0.0 0.5 0.4 0.0 2.8 7.5 2.8 5.6 0.0 0.0 0.0 7.0 9.2 0.6 0.1 1.8 3.1 0.1 2.7 0.1 3.5 0.1 0.2 15.3 0.2 2.5 2.5 1.9 0.0 0.0 3.9 3.1 0.1 3.3 0.0 0.0 0.0 1.5 0.0 0.4 1.9 0.3 0.5 0.4 0.5 0.7 0.4 0.6 0.3 0.3 0.3 0.5 0.5 0.8 0.8 0.9 0.5 1.6 0.3 12.7 15.0 11.6 11.8 13.4 5.9 5.4 8.6 12.1 11.2 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376936-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA017385: AB_1845397, HPA049014: " "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.1 15.0 12.1 9.8 14.2 1.1 10.2 9.5 17.1 15.7 11.7 8.2 6.5 5.5 12.9 10.2 10.6 10.3 13.2 14.6 10.8 13.5 10.7 11.5 24.9 4.4 10.4 14.5 12.0 7.0 15.5 6.1 21.7 10.8 11.0 7.7 11.4 7.1 9.1 10.6 7.2 8.1 15.3 7.5 8.9 7.2 12.9 3.8 3.9 11.6 5.2 5.4 11.1 8.9 1.6 2.6 0.9 2.7 1.1 3.6 0.9 5.7 5.4 5.5 8.7 13.9 13.4 10.7 11.9 12.0 10.4 10.4 4.7 8.7 2.0 13.9 24.0 10.8 7.2 9.2 16.3 5.9 4.9 6.0 5.7 7.3 9.6 1.7 4.7 9.8 8.7 7.6 10.2 30.0 3.9 9.9 12.8 10.7 1.4 1.5 3.0 4.9 3.9 10.9 3.0 8.9 12.2 5.6 5.6 12.6 7.6 14.0 5.8 4.0 33.0 21.2 11.3 7.2 7.2 1.4 1.7 0.6 5.1 3.8 6.1 0.5 2.0 0.9 3.4 1.8 2.5 1.5 1.3 2.2 2.3 1.6 2.7 1.4 0.6 1.1 2.7 2.6 3.6 0.9 12.1 14.2 9.5 17.1 10.8 13.5 10.4 14.5 10.8 3.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 57.1" "Cell line enriched" "Detected in single" 121 "HUVEC TERT2: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 8.2 0.3 0.1 1.0 0.7 3.6 5.4 0.1 0.3 2.2 5.5 0.1 4.6 2.4 2.6 57.1 1.5 2.5 2.6 10.5 0.5 0.0 0.2 0.9 3.7 6.5 0.4 0.0 1.4 0.9 0.2 0.6 2.6 0.7 2.2 1.4 0.5 1.5 0.6 4.2 1.6 5.5 2.2 0.4 2.4 1.5 1.9 0.1 0.2 2.2 1.1 0.8 2.8 2.4 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.5 0.0 0.4 0.0 0.7 0.1 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: " "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.4 4.6 6.8 8.1 8.3 10.7 10.9 6.1 6.5 4.9 7.1 5.0 5.9 9.3 4.7 6.2 3.0 6.0 4.8 9.0 8.6 4.9 6.0 4.5 4.6 7.0 9.8 6.1 7.1 5.4 5.2 10.8 5.7 9.5 16.7 8.7 2.9 13.0 10.3 6.3 2.9 8.5 5.8 7.6 4.8 10.4 7.9 6.6 7.0 4.3 6.3 4.0 6.7 8.4 5.3 4.1 11.5 4.9 19.4 11.0 14.8 8.7 9.9 5.7 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685986 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" Cytosol "Nuclear membrane" "HPA040357: AB_10967924, HPA058820: " "unprognostic (7.02e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "prognostic unfavourable (7.65e-6)" "unprognostic (2.14e-1)" "unprognostic (9.24e-3)" "unprognostic (2.80e-1)" "unprognostic (1.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (3.66e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-2)" "unprognostic (8.08e-2)" 9.8 9.9 9.8 7.2 11.6 26.5 9.6 10.0 12.8 8.3 9.3 10.0 8.0 8.6 10.1 7.0 9.4 8.4 7.3 8.8 8.6 8.7 8.4 9.3 7.9 9.7 9.2 8.5 9.7 7.8 9.4 10.4 9.8 12.0 8.3 9.0 6.7 8.9 9.7 19.1 12.7 9.3 9.1 11.1 9.6 7.9 55.9 10.1 12.4 9.5 5.6 10.4 10.2 11.8 12.7 11.7 25.7 13.5 16.6 18.5 11.6 9.7 14.4 11.8 13.5 12.6 10.7 19.7 13.7 11.6 16.0 12.3 19.3 6.8 18.8 8.2 13.0 12.0 16.4 11.2 17.1 12.0 10.6 23.3 9.0 13.0 15.9 20.4 15.8 12.0 16.0 13.8 22.4 13.8 24.1 6.2 13.1 12.3 16.9 19.7 15.9 15.2 15.8 12.9 16.8 10.5 20.6 14.7 10.9 16.1 13.7 13.4 15.0 13.0 12.7 10.3 9.6 9.2 9.7 15.9 20.0 20.8 9.7 11.3 11.2 16.1 13.0 24.0 14.7 13.5 14.3 12.7 15.4 14.7 11.7 12.5 14.6 14.8 25.7 16.6 10.6 8.4 18.5 11.6 9.8 11.6 10.0 12.8 8.6 8.7 9.2 8.5 12.0 10.1 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1, DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: " "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 4.8 4.3 6.0 9.6 11.3 15.3 5.1 12.9 10.6 5.4 9.2 3.4 6.8 4.3 5.4 5.5 9.1 5.5 3.3 6.5 6.6 5.3 4.2 7.7 4.9 13.0 7.5 5.9 5.1 4.7 4.2 11.0 5.3 10.5 4.1 10.4 3.7 5.4 7.4 7.3 8.3 6.7 5.5 9.2 5.9 5.1 17.6 7.0 10.9 15.6 7.3 14.6 5.5 5.6 2.0 9.1 9.7 12.7 1.4 1.3 10.7 15.5 25.2 13.9 11.1 2.3 5.2 13.6 18.3 7.9 15.4 14.7 15.3 12.1 35.9 3.4 7.0 18.0 18.9 10.2 25.9 16.4 13.8 16.9 19.8 13.2 0.5 30.1 14.7 1.4 1.7 23.2 7.4 7.9 25.4 15.4 14.5 10.3 25.2 9.9 7.6 6.7 17.4 29.3 14.7 5.7 15.1 9.6 10.3 14.1 4.7 6.9 12.4 13.9 5.2 13.8 11.2 17.8 19.1 7.2 17.6 27.6 11.1 17.9 14.4 4.6 12.7 1.8 1.3 4.0 1.3 1.1 1.3 1.0 9.1 2.0 1.2 1.3 9.7 1.4 1.5 1.4 0.4 10.7 6.0 11.3 12.9 10.6 6.6 5.3 7.5 5.9 10.5 7.0 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 25.9;SH-SY5Y: 23.2;WM-115: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported Nucleoplasm Nucleoplasm "HPA021212: AB_1845455, HPA061719: " "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favourable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavourable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.2 15.3 8.0 0.0 0.6 0.1 2.4 3.4 3.3 4.8 5.9 2.7 3.1 1.7 2.7 0.1 3.2 0.1 3.1 14.4 12.6 2.0 1.6 0.6 3.3 0.6 5.9 2.1 0.3 3.3 0.0 0.1 2.8 18.8 2.9 0.8 3.6 0.7 11.1 1.0 8.3 3.8 0.5 0.2 0.0 25.9 23.2 0.0 0.4 5.6 1.3 1.7 0.0 6.3 6.7 3.5 4.6 15.6 11.4 7.0 6.5 1.4 21.1 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Cell line enhanced" "Detected in some" "AF22: 8.9;AN3-CA: 9.7;CACO-2: 7.7;HAP1: 7.2;NTERA-2: 15.0;SCLC-21H: 35.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.9 8.9 9.7 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.7 0.5 0.0 1.3 0.1 0.0 7.2 0.0 0.6 0.9 3.8 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.9 0.0 0.0 15.0 1.2 0.0 0.0 0.0 0.1 0.1 35.0 5.2 1.7 0.1 2.4 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 77.5;lymphoid tissue: 37.0" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HEL: 40.0;HMC-1: 144.1;U-937: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 77.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" 610000 "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 7.3 2.4 3.3 23.5 5.6 14.0 2.6 0.8 3.6 2.3 3.0 4.7 0.3 2.2 1.9 2.6 2.4 2.0 3.7 3.3 3.3 2.5 2.2 2.5 10.7 25.1 5.4 1.2 1.2 1.5 0.2 1.4 3.2 4.1 2.5 4.5 1.5 3.2 1.0 1.0 2.5 12.9 3.3 10.8 37.0 3.1 1.3 6.3 4.0 1.7 1.8 36.7 5.8 2.0 13.7 13.2 77.5 20.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.0 0.0 16.0 144.1 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.0 0.0 0.0 11.2 0.2 0.0 12.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 13.7 0.0 20.9 0.0 77.5 11.3 19.3 0.0 18.1 0.0 13.7 0.0 0.0 13.2 13.7 0.0 0.0 4.5 0.0 20.7 6.0 0.0 6.1 3.3 5.6 0.8 3.6 3.3 2.5 5.4 1.2 4.1 6.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637698-110678114 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 56.5;testis: 30.9" "Cell line enhanced" "Detected in many" "HEL: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavourable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavourable (1.03e-5)" "prognostic unfavourable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavourable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 1.1 0.9 0.5 15.8 1.0 8.9 0.6 0.3 1.0 1.2 2.8 0.4 0.0 2.4 0.7 2.3 5.8 0.5 1.0 1.1 0.5 0.5 0.9 0.8 2.1 11.6 0.6 0.2 1.0 0.7 0.0 0.4 2.4 0.5 0.7 4.3 0.4 1.4 0.0 0.5 1.8 3.1 1.4 1.3 7.9 1.8 30.9 0.1 56.5 0.6 5.7 12.1 2.5 2.0 1.8 2.4 3.0 0.2 1.4 6.1 1.1 29.9 8.8 23.1 14.5 1.0 1.7 12.3 15.6 10.3 27.2 20.5 18.4 17.2 20.3 9.7 9.0 13.1 29.5 11.3 33.8 16.1 14.4 67.2 9.4 14.7 0.2 19.3 19.0 0.4 0.7 20.9 10.4 15.8 29.4 42.4 22.2 9.8 32.3 16.2 22.3 16.6 21.5 19.8 31.0 5.5 9.5 15.5 6.7 11.1 9.4 8.4 7.4 16.4 6.5 12.4 20.2 9.3 21.6 22.2 20.8 25.0 8.3 15.0 21.7 3.0 0.0 0.7 0.6 0.2 0.9 1.8 2.5 1.0 0.8 1.4 1.6 1.5 0.0 1.4 0.1 2.4 6.1 1.1 0.5 1.0 0.3 1.0 0.5 0.5 0.6 0.2 0.5 0.1 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008419 Supported Cytosol Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (7.43e-6)" "prognostic unfavourable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.6 11.0 35.1 13.9 0.8 2.5 11.3 20.5 11.5 22.0 19.1 16.0 8.3 19.6 11.5 7.4 24.4 33.1 11.1 24.0 16.8 17.8 28.6 28.4 14.9 0.0 25.7 15.7 0.5 0.6 13.4 12.7 15.9 24.6 20.9 21.9 7.3 20.2 15.7 23.7 12.5 21.7 28.8 14.8 6.7 11.0 22.9 14.1 12.7 12.1 4.5 14.1 13.4 9.2 16.9 17.9 16.8 18.2 10.9 18.5 32.0 9.0 29.0 21.9 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 C1GALT1 "C1GALT, T-synthase" ENSG00000106392 "Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1" Q9NS00 7 7156934-7248651 "Enzymes, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "LHCN-M2: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011294, HPA012819" Enhanced Approved "Nuclear bodies,Cytosol" 10000 "Nuclear bodies, Cytosol" "HPA011294: AB_1845623, HPA012819: AB_1845624" "unprognostic (1.52e-1)" "prognostic unfavourable (1.04e-4)" "unprognostic (7.38e-2)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.42e-5)" "unprognostic (2.03e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.83e-1)" "unprognostic (3.28e-1)" "unprognostic (8.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" 11.4 7.7 10.1 12.4 14.1 23.1 11.0 10.6 14.9 13.9 10.7 21.5 4.0 19.3 5.4 7.1 24.7 12.7 16.1 11.6 12.8 10.8 21.5 14.7 10.9 11.7 23.7 8.9 6.2 6.2 42.3 11.0 30.2 19.2 5.7 12.2 8.1 17.6 5.7 8.1 8.6 15.8 5.3 31.0 13.8 15.3 5.4 21.4 12.9 10.6 6.2 11.6 10.3 8.4 15.9 13.5 33.2 26.0 16.6 17.4 12.2 18.7 8.1 2.5 4.3 7.4 15.5 8.7 21.5 16.1 10.0 14.9 5.5 19.4 8.7 5.5 8.5 6.0 3.6 8.0 15.8 5.2 3.0 8.2 4.8 15.3 8.1 8.6 3.6 12.7 5.7 24.6 19.0 8.1 17.7 5.5 80.7 3.2 2.3 4.2 15.6 8.7 7.9 14.7 5.3 11.4 8.3 3.0 8.1 13.6 15.3 14.6 4.8 4.5 8.6 16.1 24.9 22.9 8.7 10.5 8.9 9.9 10.6 11.7 17.8 33.2 11.1 31.2 16.1 16.5 16.9 15.9 15.0 17.4 12.2 13.7 15.7 17.0 24.3 16.6 26.0 13.5 13.0 12.2 10.1 14.1 10.6 14.9 12.8 10.8 23.7 8.9 19.2 21.4 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavourable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.2 22.9 10.2 20.4 16.6 13.7 8.1 10.7 7.5 13.6 9.7 25.9 10.1 22.6 9.7 9.8 14.3 30.0 14.2 10.2 14.8 24.2 32.3 17.4 13.5 8.3 25.4 16.3 10.4 11.7 19.7 22.5 14.5 22.7 12.6 11.9 25.4 16.2 37.8 24.5 17.4 28.4 30.6 23.5 10.0 12.9 20.5 10.3 15.0 10.7 12.5 8.3 10.7 13.0 20.6 17.0 16.0 21.5 26.2 16.9 46.2 8.3 24.5 17.7 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol 550000 Cytosol "CAB031904: AB_630964, HPA051409: " "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavourable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.6 2.9 0.0 15.1 5.6 7.3 8.6 4.8 9.9 9.4 5.3 0.6 0.2 2.0 5.8 0.6 0.0 1.1 6.2 0.1 21.1 11.6 6.9 7.4 8.4 1.0 92.0 5.9 0.9 13.9 1.5 8.3 1.5 0.2 3.7 2.2 0.0 8.5 2.0 5.7 0.0 0.1 0.2 5.9 0.6 0.9 3.7 1.5 0.1 0.8 0.9 14.9 4.3 4.5 5.6 6.4 10.8 0.0 0.0 0.2 9.6 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.7;U-266/70: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favourable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.5 2.9 0.1 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.5 2.0 1.4 0.3 0.2 1.3 3.5 0.5 0.5 46.7 1.8 5.6 8.3 0.2 0.5 0.1 5.1 0.1 2.3 1.2 0.1 0.3 0.1 0.2 0.7 2.9 10.9 2.2 1.9 1.1 8.3 1.6 2.6 0.1 2.7 4.5 2.0 5.5 2.0 0.0 1.5 1.3 0.1 2.4 3.6 7.7 1.6 21.5 6.7 4.7 3.6 3.6 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583717-209613938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 34.4;ovary: 29.2" "Cell line enhanced" "Detected in some" "BJ: 2.0;hTEC/SVTERT24-B: 12.1;NTERA-2: 1.9;SK-MEL-30: 3.6;U-138 MG: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.17e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.49e-3)" "unprognostic (2.56e-2)" "unprognostic (1.93e-1)" "unprognostic (6.79e-2)" "unprognostic (3.98e-1)" "unprognostic (3.59e-3)" "unprognostic (8.55e-3)" "unprognostic (3.17e-2)" "unprognostic (1.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.27e-1)" "unprognostic (9.10e-2)" "unprognostic (3.43e-2)" 0.7 3.5 7.5 0.9 34.4 1.0 0.7 1.3 27.8 1.1 0.8 0.7 1.2 0.8 1.8 6.1 0.6 0.9 1.5 0.6 10.9 9.2 6.9 0.9 1.2 0.8 3.6 17.7 29.2 1.3 0.6 2.0 2.8 3.9 4.6 0.8 0.6 0.6 7.4 0.6 0.6 0.8 2.3 0.9 6.1 0.7 1.4 2.7 0.0 0.7 0.0 0.8 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.0 0.3 0.8 0.3 0.0 0.2 0.0 0.0 0.8 0.2 0.0 0.0 1.3 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 12.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.2 2.1 0.2 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 34.4 1.3 27.8 10.9 9.2 3.6 17.7 3.9 2.7 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;SCLC-21H: 9.5;U-87 MG: 8.0" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: , HPA051785: , HPA053973: " "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 2.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.0 9.5 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.8 0.2 0.1 0.2 0.7 0.0 1.0 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 5.2 0.0 0.2 0.1 2.3 0.1 0.9 0.1 0.0 0.0 41.0 2.2 0.2 0.0 0.0 1.9 0.1 0.2 0.2 0.3 0.2 0.0 0.5 0.4 0.1 0.1 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: , HPA051785: , HPA053973: " "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.3 15.8 5.3 34.6 66.2 5.6 33.5 22.4 13.2 11.4 9.6 4.0 20.5 4.9 23.3 0.5 9.8 5.2 13.5 7.8 2.5 0.0 5.2 11.0 17.5 0.0 0.0 42.3 7.2 10.2 25.3 11.7 0.8 9.2 24.8 3.8 2.0 0.8 2.2 5.3 4.0 18.5 0.1 13.5 9.7 4.3 4.3 4.5 6.8 4.5 0.1 5.5 7.0 34.9 8.2 14.8 6.6 7.1 3.6 17.6 18.0 1.2 16.4 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell line enhanced" "Detected in all" "PC-3: 45.4;SK-BR-3: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 10.9 7.9 7.1 13.6 5.2 8.6 8.4 7.5 12.9 10.4 8.5 12.2 11.8 8.1 7.9 9.7 17.0 5.6 6.4 8.3 7.3 6.7 5.5 6.1 5.5 2.6 7.5 9.3 4.5 5.8 10.3 7.2 8.8 6.0 12.1 5.7 7.6 12.5 11.2 5.2 45.4 11.4 7.5 4.3 5.4 15.9 3.7 8.6 4.3 57.2 3.7 10.7 4.7 10.8 7.7 12.4 4.2 10.1 3.7 4.4 7.5 8.3 21.5 2.7 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.2;MOLT-4: 12.6;SH-SY5Y: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 1.0 0.3 1.1 0.0 0.3 3.2 3.8 3.7 0.0 0.0 0.0 2.0 0.1 0.1 3.1 0.3 2.8 41.2 2.6 0.6 1.3 0.0 0.1 0.2 0.1 0.1 0.0 8.0 0.8 0.6 0.0 1.5 0.2 0.0 12.6 0.0 1.9 0.1 1.9 2.4 0.1 1.4 0.0 9.1 16.1 0.5 0.0 2.7 0.0 0.2 0.0 7.8 4.6 0.0 6.9 1.3 0.1 0.0 3.8 0.0 3.0 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.9;salivary gland: 27.1" "Cell line enhanced" "Detected in many" "HeLa: 17.8;U-87 MG: 20.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favourable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 4.3 10.2 15.3 5.1 21.4 3.7 4.7 23.2 38.9 4.1 3.2 2.2 4.0 3.1 7.5 5.2 4.2 3.7 3.8 5.7 13.8 6.8 1.5 1.0 4.0 2.5 5.5 16.0 6.0 7.5 5.0 10.1 2.3 11.2 3.3 3.1 2.5 27.1 11.2 2.2 7.8 3.7 6.2 2.2 4.3 2.9 6.1 5.0 1.7 7.2 2.3 2.5 5.6 4.9 0.1 1.6 5.6 4.1 0.0 1.0 1.1 4.8 8.4 0.9 4.2 3.0 5.4 0.3 3.4 3.7 3.2 1.5 3.0 1.5 2.9 3.6 6.4 14.5 2.3 4.1 2.0 0.1 7.7 3.3 17.8 1.1 3.1 0.5 2.6 4.1 3.5 6.1 2.1 1.4 2.6 0.1 1.6 1.3 4.0 1.9 0.9 7.9 2.1 3.7 3.4 3.5 3.1 4.9 2.7 1.3 10.0 2.2 3.8 1.1 2.0 5.6 7.6 7.1 2.7 0.4 0.2 0.1 20.5 2.8 0.7 0.0 1.8 3.6 0.6 3.9 1.0 0.0 0.6 0.5 1.6 0.1 0.6 0.3 5.6 0.0 4.1 0.8 0.0 1.1 15.3 21.4 23.2 38.9 13.8 6.8 5.5 16.0 11.2 5.0 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237691-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 125.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 125.5" "Group enriched" "Detected in many" 5 "classical monocyte: 14.2;eosinophil: 26.1;intermediate monocyte: 19.4;myeloid DC: 7.2;neutrophil: 17.2;non-classical monocyte: 16.5" "Group enriched" "Detected in all" 5 "dendritic cells: 7.2;granulocytes: 26.1;monocytes: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 11.7 6.5 19.7 7.8 30.2 13.8 8.8 125.5 45.5 9.0 9.5 7.1 2.6 12.8 8.6 5.3 8.3 11.8 6.3 6.9 11.2 5.1 7.1 8.9 9.6 6.9 6.2 17.3 10.5 5.8 6.4 4.1 7.5 9.1 12.2 9.7 6.2 7.5 13.2 5.1 9.1 13.2 10.3 6.2 14.1 7.6 3.6 5.8 5.2 6.1 4.5 7.2 7.2 7.4 2.2 7.2 26.1 19.4 3.6 2.2 6.3 12.3 9.3 6.9 13.4 20.8 19.4 10.6 10.2 10.9 8.4 7.7 9.7 5.3 19.1 8.6 20.7 10.2 8.5 11.0 6.6 13.1 16.7 9.5 6.2 9.5 14.1 21.6 9.1 12.5 16.4 7.9 18.0 19.6 11.0 10.4 8.1 12.0 23.9 17.8 5.0 10.5 15.6 8.0 16.9 8.1 13.8 26.6 10.6 13.4 7.2 8.5 17.9 26.4 14.3 6.9 5.6 5.8 5.6 39.7 23.6 14.5 12.9 15.1 6.8 0.7 14.2 26.1 2.1 19.4 2.2 2.2 1.7 1.9 7.2 1.2 1.5 1.7 17.2 3.6 16.5 1.6 1.3 6.3 19.7 30.2 125.5 45.5 11.2 5.1 6.2 17.3 9.1 5.8 CAMKMT "C2orf34, CLNMT" ENSG00000143919 "Calmodulin-lysine N-methyltransferase" Q7Z624 2 44361950-44772592 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067912 Supported Nucleoplasm Nucleoplasm "HPA067912: " "unprognostic (2.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.96e-1)" "unprognostic (2.39e-2)" "prognostic favourable (9.10e-4)" "unprognostic (1.03e-1)" "unprognostic (9.58e-3)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (7.42e-2)" "unprognostic (8.76e-2)" "unprognostic (1.37e-1)" "unprognostic (3.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (8.57e-2)" 7.1 8.0 13.9 10.8 21.7 13.9 8.2 15.4 13.1 9.8 10.8 8.2 8.7 8.7 11.0 10.5 8.8 8.1 14.8 7.3 11.8 14.8 11.4 7.0 8.2 8.1 14.1 4.3 6.7 17.6 15.7 17.6 5.2 13.7 5.8 10.9 8.4 12.0 6.4 10.9 9.7 10.8 8.2 10.5 8.4 7.8 19.0 12.6 13.7 12.1 8.1 10.7 7.9 10.0 17.7 9.9 9.3 8.5 7.7 17.2 6.9 7.0 4.4 5.4 4.9 5.7 5.8 11.5 5.9 4.1 3.0 3.9 8.1 6.4 6.8 6.6 3.8 5.9 7.3 9.1 5.3 25.4 10.5 10.0 9.3 15.2 2.2 6.5 7.1 2.4 5.6 4.1 7.8 4.4 7.9 12.1 4.9 7.3 11.8 13.2 9.9 4.7 7.0 6.4 13.6 14.6 7.9 10.6 9.6 5.6 16.8 6.2 6.1 5.5 6.0 4.1 4.8 4.9 4.3 9.7 8.0 12.3 4.5 11.5 3.1 9.3 8.5 5.9 11.7 6.7 11.7 17.7 11.2 9.7 9.5 13.4 17.2 13.5 5.1 7.7 7.1 9.9 16.0 6.9 13.9 21.7 15.4 13.1 11.8 14.8 14.1 4.3 13.7 12.6 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871513-10923070 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 64.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073" Supported Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "CAB032961: AB_2068446, HPA043561: , HPA048073: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (8.37e-4)" 12.2 8.8 12.3 12.6 16.1 13.2 9.6 12.5 17.7 15.8 14.0 9.3 9.0 11.5 19.6 9.1 20.5 14.8 12.4 14.7 11.2 7.2 9.3 14.5 8.9 12.4 7.8 10.2 13.0 16.9 8.2 6.9 15.3 9.5 12.6 10.2 12.0 11.4 13.2 64.3 12.5 12.0 15.6 6.6 9.8 11.1 17.5 8.6 9.4 10.0 12.7 15.6 15.8 15.9 1.3 1.6 0.3 1.4 0.1 2.6 0.4 22.4 16.7 24.1 32.6 20.1 27.5 23.1 16.2 28.1 24.1 23.2 25.8 8.3 31.0 19.4 28.2 21.5 24.5 24.3 15.2 34.7 20.0 9.5 10.9 31.3 17.2 14.3 12.4 18.8 15.9 16.4 19.8 30.4 22.8 27.9 14.1 40.7 24.9 12.3 29.7 27.9 34.9 12.3 36.0 14.5 11.7 17.5 16.8 11.6 14.0 15.6 14.0 12.3 18.2 29.0 16.4 27.5 18.9 27.2 21.4 27.1 19.1 23.0 12.6 0.0 1.4 0.2 1.2 1.4 0.5 1.3 0.9 2.6 1.3 1.3 1.0 0.9 0.3 0.1 0.7 1.6 0.8 0.4 12.3 16.1 12.5 17.7 11.2 7.2 7.8 10.2 9.5 8.6 CARNMT1 "C9orf41, FLJ25795" ENSG00000156017 "Carnosine N-methyltransferase 1" Q8N4J0 9 74981020-75028423 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026756 Uncertain "HPA026756: AB_1845824" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (2.99e-2)" "unprognostic (4.81e-2)" "unprognostic (3.48e-1)" "unprognostic (1.56e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (3.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.00e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" 7.7 8.3 8.0 12.9 17.5 8.4 8.5 22.9 11.6 11.3 13.5 5.7 11.3 14.6 10.0 10.7 15.8 7.8 10.9 7.5 7.6 6.0 14.9 20.2 7.3 10.6 6.3 7.9 8.8 16.5 16.1 12.5 7.6 5.4 10.7 10.5 7.7 13.9 12.3 9.6 10.2 23.3 8.7 6.6 9.9 9.0 22.1 8.6 15.1 16.6 8.7 11.0 9.7 12.8 3.5 1.5 2.1 1.7 3.1 4.7 1.4 14.4 8.7 3.7 9.5 6.1 13.0 13.6 12.8 5.5 5.1 4.7 2.2 9.9 22.8 6.9 9.5 14.4 11.2 14.0 14.6 19.9 8.6 11.6 8.9 10.1 7.4 21.0 11.5 8.8 7.1 9.6 10.0 10.2 9.8 20.6 9.9 3.9 15.3 5.9 17.0 7.8 7.4 11.0 13.8 13.5 10.4 3.6 1.9 9.8 26.1 4.9 13.2 6.4 8.0 8.4 10.9 10.0 11.2 14.7 18.7 6.9 13.1 14.6 5.3 0.0 1.0 2.1 3.2 1.7 4.5 3.5 3.2 4.7 1.2 1.9 3.6 3.8 0.4 3.1 1.0 1.5 4.1 1.4 8.0 17.5 22.9 11.6 7.6 6.0 6.3 7.9 5.4 8.6 CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044404 Uncertain Approved Nucleoplasm Nucleoplasm "HPA044404: AB_10964353" "unprognostic (4.02e-2)" "unprognostic (4.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (3.66e-2)" "unprognostic (2.18e-2)" "unprognostic (9.83e-2)" "unprognostic (4.74e-2)" "unprognostic (4.95e-3)" "unprognostic (2.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (1.93e-1)" "unprognostic (7.07e-2)" "unprognostic (2.59e-3)" 8.6 21.6 16.6 7.1 24.2 4.1 13.2 20.5 24.8 10.0 13.2 10.9 7.5 5.0 11.7 12.5 5.1 9.2 8.1 13.6 25.9 22.2 10.2 7.1 9.0 9.2 13.1 16.6 14.1 7.8 12.7 22.8 9.8 20.0 11.8 15.9 8.4 22.6 8.2 11.3 3.7 6.3 9.7 13.7 8.0 6.0 10.1 11.5 7.3 13.2 2.9 8.3 9.0 6.3 1.8 1.1 0.2 0.7 1.8 4.7 0.7 3.0 5.8 20.1 7.4 6.1 7.4 3.4 4.1 7.3 4.6 6.0 3.7 7.5 7.7 10.8 5.5 1.7 5.0 1.4 9.1 12.3 4.0 6.9 5.0 6.6 5.2 11.3 0.0 6.7 5.3 4.2 6.0 7.2 3.7 17.0 11.2 4.4 15.6 6.4 10.2 4.7 10.8 16.3 6.0 9.2 8.4 7.6 26.0 6.4 12.0 4.0 3.1 7.1 3.8 11.5 9.1 9.4 5.9 16.3 15.2 16.1 6.3 2.6 7.4 0.0 0.6 0.2 1.9 0.7 4.7 1.8 2.8 2.3 1.1 1.7 2.9 2.2 0.0 1.8 0.6 1.0 1.7 0.7 16.6 24.2 20.5 24.8 25.9 22.2 13.1 16.6 20.0 11.5 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.8 13.9 13.3 7.9 9.0 7.4 4.3 9.5 7.9 5.6 5.1 29.9 17.7 0.1 4.9 11.8 21.8 14.7 9.7 9.4 9.6 8.2 0.0 12.5 10.6 9.3 1.7 1.4 8.4 26.7 10.6 13.6 4.5 0.8 8.5 12.1 12.7 3.1 0.7 12.2 9.1 5.1 32.8 5.2 12.6 23.7 12.2 6.5 17.9 7.1 5.4 7.7 0.3 5.3 10.5 10.6 8.9 5.2 3.3 2.0 3.6 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206276-119313926 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 9.9 5.5 9.1 17.0 11.1 11.1 8.8 10.7 12.0 6.2 7.5 8.7 3.0 5.7 9.9 5.3 7.5 7.4 6.3 5.9 8.0 9.6 5.5 4.0 10.3 16.3 8.1 6.9 6.3 5.6 16.6 4.1 9.1 9.3 5.3 7.5 6.4 5.4 7.1 3.9 7.4 8.6 10.6 8.9 13.3 7.3 32.3 5.1 40.9 6.0 5.5 15.6 7.6 7.7 1.8 3.3 11.8 3.7 0.6 1.9 1.0 6.3 4.8 16.8 10.5 5.0 6.0 9.9 6.8 7.1 6.6 6.6 10.2 7.8 15.0 6.2 8.6 9.3 11.5 5.8 14.5 8.5 2.7 15.4 3.6 3.1 6.2 17.9 17.6 5.2 6.5 16.9 18.2 16.3 12.4 6.3 11.9 6.8 9.5 10.0 8.7 5.3 10.3 8.4 2.8 5.9 5.1 2.3 7.0 12.7 5.5 4.5 5.8 15.1 13.6 10.3 7.3 7.2 8.9 2.1 3.1 12.2 4.2 15.5 7.3 0.8 3.2 2.4 1.3 3.7 1.1 1.8 1.6 1.3 3.3 1.8 1.8 1.9 11.8 0.6 3.1 1.8 1.4 1.0 9.1 11.1 10.7 12.0 8.0 9.6 8.1 6.9 9.3 5.1 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 38.4 9.0 3.7 19.5 4.9 15.5 16.3 24.4 3.8 13.7 18.7 5.9 7.7 9.3 13.8 12.2 8.3 12.5 13.4 27.5 3.8 4.8 7.4 6.7 16.3 19.1 4.4 1.9 17.7 6.8 3.4 13.5 25.4 7.9 12.9 8.0 11.6 9.1 6.3 10.3 8.5 13.8 25.6 5.7 16.4 12.4 9.2 5.2 11.6 13.5 7.0 18.0 24.9 24.1 5.1 3.1 2.8 2.1 10.3 9.9 1.6 1.6 2.2 7.6 3.7 8.7 8.8 4.9 5.6 2.8 1.6 2.7 2.9 1.9 3.6 4.0 3.0 2.8 1.0 1.0 2.0 2.7 2.9 1.9 11.7 1.8 12.8 1.3 1.4 8.4 3.0 4.4 12.0 5.5 2.0 11.5 3.5 2.0 1.9 0.9 2.7 3.2 4.1 2.3 0.6 4.0 7.2 5.8 6.4 6.7 0.8 8.8 1.6 2.9 3.1 23.4 2.0 3.2 1.3 6.5 0.5 5.6 6.2 1.2 1.5 0.7 1.5 2.8 9.9 0.9 8.8 2.2 5.1 5.6 1.3 5.1 4.4 8.0 1.0 10.3 2.1 3.1 5.6 1.6 3.7 4.9 24.4 3.8 3.8 4.8 4.4 1.9 7.9 5.2 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800634 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 66.8" "Cell line enhanced" "Detected in some" "A-431: 19.0;BEWO: 13.1;CACO-2: 12.8;CAPAN-2: 26.3;HaCaT: 18.4;HBEC3-KT: 16.0;hTCEpi: 12.2;RT4: 16.0;SK-BR-3: 14.6;T-47d: 10.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm Nucleoplasm "CAB008087: AB_2228531, HPA035266: " "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favourable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.0 0.5 8.5 0.2 0.0 4.8 0.1 0.4 4.4 39.5 0.1 3.2 29.5 1.7 1.7 22.0 1.4 18.8 0.1 0.6 0.0 4.9 15.1 1.3 0.1 0.1 0.3 0.8 18.1 0.9 0.7 4.1 0.2 6.9 6.9 0.5 11.4 5.2 0.1 20.8 66.8 0.4 0.1 0.1 10.2 1.6 0.1 0.5 1.9 13.2 15.7 7.6 8.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 12.8 26.3 0.0 0.0 0.0 18.4 0.0 16.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.0 14.6 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.4 0.6 0.0 0.1 0.3 0.2 0.1 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743697-107761667 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 15.8 12.0 11.7 13.6 20.0 38.8 16.8 18.7 19.4 15.3 17.2 19.2 11.6 10.8 22.9 9.7 14.4 14.2 10.2 11.5 11.9 10.7 11.6 12.5 12.9 16.5 12.6 14.3 18.2 15.5 14.5 17.2 13.5 16.5 18.7 13.0 14.7 12.8 19.6 32.6 16.6 14.4 16.2 15.1 15.8 14.7 21.1 13.3 29.0 15.8 11.8 19.3 17.6 12.7 17.9 16.7 32.2 15.7 23.4 40.3 20.1 13.5 15.5 12.0 15.3 11.0 9.6 8.2 10.2 10.6 11.5 11.4 10.4 13.8 19.6 14.8 11.5 9.6 16.6 12.4 15.8 13.9 10.5 16.0 11.4 8.7 12.8 23.5 15.7 10.0 11.5 15.5 17.0 11.8 25.1 16.7 11.0 23.1 32.1 16.0 17.2 10.6 14.9 13.0 20.3 8.7 12.5 12.8 20.0 15.2 22.4 11.1 7.5 12.0 11.5 17.9 12.9 16.9 15.6 27.2 29.5 31.8 11.0 14.7 15.1 32.2 14.2 23.3 19.0 14.7 28.0 17.9 30.1 21.8 16.7 17.4 20.9 19.6 21.9 23.4 15.7 9.0 40.3 20.1 11.7 20.0 18.7 19.4 11.9 10.7 12.6 14.3 16.5 13.3 CBLL2 "CT138, FLJ25735, HAKAIL, ZNF645" ENSG00000175809 "Cbl proto-oncogene like 2" Q8N7E2 X 22272943-22274461 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favourable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 12.6 9.7 10.9 9.8 13.7 14.2 27.2 14.5 16.4 20.3 13.4 13.2 17.2 9.9 20.4 24.2 17.4 18.8 12.4 33.8 11.1 11.2 31.2 34.4 15.4 11.2 13.4 11.1 49.1 20.6 14.5 12.1 14.4 15.9 18.0 14.5 15.8 14.0 12.3 20.6 14.6 10.0 27.6 15.8 11.3 13.0 9.7 13.9 11.2 35.8 15.3 16.1 33.6 17.7 9.3 13.7 3.5 3.1 4.4 10.7 3.0 6.5 5.4 30.8 29.6 15.8 21.8 24.9 8.1 16.3 12.5 16.5 18.3 7.3 23.0 5.4 5.9 11.9 21.4 15.3 16.9 6.6 18.1 13.5 5.1 17.2 46.5 24.9 12.7 29.6 25.8 8.9 86.7 9.4 16.5 18.2 8.2 10.5 14.4 17.0 18.5 10.3 17.8 15.2 9.6 13.0 9.7 24.6 25.6 5.6 13.0 36.3 4.1 18.3 4.0 7.1 9.1 8.6 10.5 8.6 10.7 15.7 2.4 21.1 8.2 3.5 3.1 0.0 6.7 1.1 9.1 9.3 7.4 8.3 13.7 8.4 7.7 10.7 0.5 4.4 1.1 13.7 9.9 3.0 10.9 13.7 14.5 16.4 11.1 11.2 13.4 11.1 15.9 13.9 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853230 "Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 94.9;seminal vesicle: 104.1" "Cell line enhanced" "Detected in some" "Daudi: 49.8;Karpas-707: 13.9;MOLT-4: 12.6;REH: 10.0;U-266/70: 10.8;U-698: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 15.3" "Group enriched" "Detected in all" 4 "B-cells: 9.0;dendritic cells: 5.1;NK-cells: 15.3" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favourable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 4.1 3.3 3.8 17.6 8.5 9.3 2.6 0.7 12.0 1.0 3.2 10.4 14.6 4.3 0.7 0.9 2.3 2.4 1.5 5.0 4.0 4.2 1.2 5.4 4.7 16.1 4.9 3.1 0.6 0.7 0.0 2.5 0.6 3.1 10.8 2.7 4.4 2.8 104.1 14.2 0.5 6.2 0.9 1.8 20.6 2.0 0.7 2.5 94.9 2.8 2.0 13.2 7.6 0.9 9.0 5.1 1.3 2.2 15.3 2.3 3.7 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 13.9 0.0 0.0 12.6 3.0 0.0 0.0 10.0 0.0 7.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 2.2 0.2 0.0 0.0 0.0 0.0 10.8 0.1 9.4 0.1 2.4 0.1 0.0 1.7 0.0 1.1 2.2 0.3 9.0 1.4 1.2 4.1 6.6 2.3 1.8 1.3 15.3 1.4 5.1 2.1 3.7 3.8 8.5 0.7 6.2 4.0 4.2 4.9 3.1 3.1 2.5 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34" P49427 19 531712-542092 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370" "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavourable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 16.5 15.9 21.3 11.3 19.1 24.7 20.4 25.7 30.9 16.0 20.5 19.5 10.5 15.4 13.3 13.4 15.6 14.5 13.6 35.6 21.1 18.2 12.1 36.0 13.0 9.9 18.5 19.8 17.0 37.4 11.3 17.0 24.9 16.2 17.2 10.6 15.3 26.4 18.5 63.9 19.0 13.2 18.6 14.3 12.7 15.7 43.6 15.0 12.2 13.1 17.0 8.7 19.2 16.4 2.9 2.8 11.5 4.5 1.5 4.1 1.3 18.4 18.4 23.7 19.5 10.8 10.3 23.7 16.6 12.7 17.9 18.7 28.6 11.3 10.2 17.4 11.8 12.8 18.6 14.0 9.2 16.6 50.0 9.4 12.2 30.9 26.9 13.2 11.4 13.3 21.0 15.1 15.8 21.3 40.2 20.4 11.8 26.4 18.0 17.6 29.9 17.9 16.7 12.2 17.1 13.5 11.0 30.9 22.9 14.4 15.0 27.6 12.0 19.4 17.4 13.1 15.6 30.4 22.1 20.4 15.6 13.6 17.9 18.7 13.5 4.5 3.5 6.2 2.3 3.4 1.7 2.9 3.2 4.1 2.8 1.7 2.5 2.4 11.5 1.5 4.5 2.3 3.1 1.3 21.3 19.1 25.7 30.9 21.1 18.2 18.5 19.8 16.2 15.0 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: " "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 17.2 15.2 19.1 8.6 21.1 3.9 14.0 29.2 20.4 21.1 19.3 16.4 13.1 16.9 15.8 9.9 12.3 12.9 16.6 14.1 21.7 17.7 20.8 17.0 11.7 3.5 20.0 16.3 17.4 15.1 29.3 29.6 14.8 19.3 21.1 12.4 11.0 8.4 18.5 11.9 7.6 17.2 27.6 16.6 8.8 25.2 26.7 19.9 0.7 9.8 7.3 2.5 23.4 23.1 0.1 0.7 2.0 0.1 0.0 0.1 0.0 9.3 8.9 9.5 4.4 9.5 11.8 3.3 10.7 15.2 7.4 7.8 7.2 21.3 0.0 11.6 17.8 4.3 6.9 6.0 9.1 0.0 5.6 7.2 10.5 2.8 10.8 5.8 3.2 8.2 7.7 12.0 12.1 24.8 18.4 0.0 12.1 2.5 0.1 1.0 7.7 8.5 0.0 16.0 0.0 12.0 18.1 6.8 10.0 18.2 7.6 10.7 9.9 0.3 24.9 13.7 7.1 15.5 14.2 0.0 0.0 0.0 18.1 0.0 18.2 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 19.1 21.1 29.2 20.4 21.7 17.7 20.0 16.3 19.3 19.9 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932379-103057462 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved 12000 "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favourable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 32.2 22.7 33.1 14.8 33.2 3.1 19.8 30.3 42.1 26.7 21.8 42.3 21.5 26.0 27.0 18.7 28.3 26.0 28.1 30.7 31.4 25.5 23.7 20.1 26.4 7.9 31.2 28.4 29.7 28.8 32.5 25.9 25.6 27.0 25.1 18.2 23.7 23.0 28.8 17.0 23.8 29.6 28.7 24.3 18.3 25.5 21.8 31.0 2.1 26.3 15.9 12.4 25.2 32.6 0.9 0.2 0.0 2.0 0.0 0.4 0.1 13.1 26.4 17.0 12.4 18.9 21.7 17.1 15.1 16.0 16.0 14.8 9.0 15.5 0.0 16.6 29.4 16.8 17.5 18.0 17.1 16.0 7.9 7.2 21.3 9.0 20.6 0.0 7.8 18.7 18.7 16.4 15.8 31.1 5.8 3.7 15.4 27.6 0.1 1.6 8.1 21.8 0.0 14.3 0.3 20.5 25.9 12.4 13.5 26.8 10.1 11.3 15.6 4.6 39.5 15.4 10.4 34.0 14.0 4.9 5.2 3.8 17.3 1.6 14.9 0.0 1.4 0.0 0.0 2.0 0.0 0.9 0.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 33.1 33.2 30.3 42.1 31.4 25.5 31.2 28.4 27.0 31.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823387-64844569 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 19.1;HaCaT: 14.3;MCF7: 19.3;RT4: 11.7;SK-BR-3: 11.9;T-47d: 11.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 19.4" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 4 "cerebellum: 5.9" "Low region specificity" "Detected in single" "HPA027382, HPA061836" Enhanced Supported Cytosol Cytosol "HPA027382: AB_1846378, HPA061836: " "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favourable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 2.7 0.8 2.1 0.5 1.1 3.5 19.4 0.8 2.9 9.1 0.8 6.3 8.2 1.0 8.0 14.3 2.9 10.5 0.5 0.7 0.0 3.5 0.5 4.2 0.7 0.5 0.5 1.5 7.9 7.0 6.5 13.0 2.0 4.4 3.4 1.0 14.3 7.6 0.5 22.4 19.7 1.6 0.8 0.8 8.5 2.5 0.7 1.8 3.9 8.1 7.7 5.4 6.3 0.4 0.0 0.0 0.0 0.2 1.0 0.1 5.5 0.8 0.5 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 7.4 4.7 0.1 2.8 0.0 14.3 0.8 5.6 0.0 0.2 2.2 0.4 3.1 2.3 0.0 0.1 1.4 0.0 7.0 0.0 0.1 0.0 3.7 0.0 0.0 19.3 0.1 1.0 1.7 0.8 0.8 0.3 2.6 3.4 11.7 10.2 0.5 1.8 11.9 0.3 11.6 0.2 0.0 0.0 2.0 0.0 0.0 1.3 1.3 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.8 0.5 19.4 0.8 0.7 0.0 0.5 0.5 2.0 0.7 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500893-91525764 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: " "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavourable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 2.5 3.7 5.7 7.6 8.9 15.4 4.3 19.4 10.3 2.5 4.2 1.4 0.9 4.2 2.8 2.6 4.7 1.7 2.6 1.9 6.8 5.2 3.6 2.3 5.1 11.7 4.0 4.7 3.7 2.4 2.2 12.3 7.9 5.2 2.7 6.8 2.3 2.5 2.3 1.0 6.8 4.9 3.3 5.9 15.1 2.6 21.2 4.7 18.7 2.5 4.5 12.0 4.2 3.0 1.6 3.5 0.1 1.6 2.4 6.5 2.1 14.0 4.2 27.1 7.7 0.6 3.6 8.6 5.3 4.2 10.5 11.5 8.7 5.0 9.7 7.5 3.3 6.1 17.8 6.0 14.6 16.1 15.3 14.8 12.0 4.1 1.0 16.1 5.4 1.9 1.8 9.6 5.5 4.0 19.5 14.2 7.2 5.1 13.7 14.4 22.5 9.9 17.1 22.5 6.2 4.6 10.6 21.6 8.5 16.9 4.7 9.4 4.4 7.9 3.3 12.0 10.6 9.2 8.0 5.2 6.6 26.1 4.3 15.6 4.4 0.0 1.6 0.0 5.9 1.2 5.2 1.5 4.5 5.6 3.5 1.6 2.5 5.1 0.1 2.4 0.3 2.1 6.5 2.1 5.7 8.9 19.4 10.3 6.8 5.2 4.0 4.7 5.2 4.7 CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863736 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Approved Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: " "unprognostic (7.81e-2)" "prognostic favourable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" 40.4 40.8 24.3 20.2 28.1 15.3 42.9 50.7 39.5 37.1 37.2 21.5 33.9 24.8 33.4 23.0 39.4 30.1 34.5 44.4 23.1 27.9 34.8 66.3 27.1 22.4 24.1 26.4 52.7 40.0 47.1 24.9 43.7 21.8 36.8 16.1 29.3 42.2 38.8 21.0 29.6 32.6 31.8 21.0 25.6 29.5 20.2 16.4 30.4 47.1 19.9 17.3 41.8 42.8 4.8 6.1 20.6 6.5 8.2 8.4 2.7 12.3 26.8 7.5 15.1 41.3 28.6 22.4 21.7 24.3 15.4 15.4 15.6 23.8 8.3 41.1 25.0 19.5 12.2 14.0 7.1 20.7 24.5 5.9 20.0 22.8 28.8 8.8 15.4 48.3 24.8 20.7 9.5 19.3 8.8 21.5 13.9 39.4 11.9 17.4 18.0 20.0 23.3 9.4 24.1 20.3 11.9 31.2 17.5 11.5 24.5 17.1 18.3 23.9 16.7 22.9 7.2 18.6 11.1 16.0 18.1 5.9 25.0 14.2 13.8 7.5 6.5 20.6 6.9 4.6 4.6 4.7 6.4 7.3 3.0 4.8 6.3 5.9 16.4 8.2 5.7 6.1 8.4 2.7 24.3 28.1 50.7 39.5 23.1 27.9 24.1 26.4 21.8 16.4 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 88.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 6.1;T-reg: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;NK-cells: 6.1;T-cells: 5.7" "Low region specificity" "Detected in single" "HPA003387, CAB003799" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003799: AB_344898, HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favourable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavourable (1.10e-6)" "prognostic unfavourable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavourable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 4.1 2.2 0.8 17.8 2.4 17.8 4.4 0.7 1.6 4.2 6.5 1.1 3.4 6.1 2.9 4.8 19.0 1.5 2.4 2.3 0.9 0.7 3.1 1.7 5.7 15.1 1.7 0.6 2.2 1.0 0.5 4.4 13.3 1.2 1.5 8.3 1.0 3.8 2.9 1.0 4.9 8.3 2.7 2.5 8.3 5.0 13.8 1.2 88.4 1.8 16.7 20.1 3.2 6.9 0.9 1.7 0.0 0.2 6.1 5.7 1.8 48.2 18.4 48.9 19.3 3.2 4.9 20.1 36.5 26.6 44.5 42.9 43.0 42.7 44.2 14.2 10.0 30.0 33.2 21.2 46.4 31.4 24.2 23.2 18.1 24.9 0.5 35.5 24.0 0.9 2.1 28.8 28.1 26.7 35.3 54.5 49.5 12.8 44.6 25.5 21.5 38.7 38.8 45.5 21.7 17.0 16.0 22.9 20.1 24.5 37.3 18.9 40.2 21.8 11.0 19.0 40.6 20.0 49.8 21.4 34.3 39.9 16.4 39.8 23.6 0.0 0.0 0.0 0.5 0.2 0.5 0.9 1.5 2.7 0.5 0.5 0.5 1.5 0.0 6.1 0.2 1.7 5.7 1.8 0.8 2.4 0.7 1.6 0.9 0.7 1.7 0.6 1.2 1.2 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Nucleoplasm "Midbody, Midbody ring" "HPA007451: , HPA059634: , HPA067060: " "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favourable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favourable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.5 9.5 7.7 3.1 3.2 6.1 8.0 12.0 6.8 8.6 2.9 7.3 11.1 12.9 6.2 10.4 10.2 3.3 16.8 5.4 2.8 8.0 5.1 10.6 0.8 13.2 8.2 9.3 7.4 5.6 5.4 8.2 15.0 13.3 1.7 9.8 19.0 9.9 23.5 15.6 7.2 14.4 10.4 18.1 15.4 11.6 7.5 16.3 15.1 7.0 3.5 16.5 13.0 13.2 5.9 15.1 6.1 8.2 6.6 3.6 4.0 8.9 14.2 8.3 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702730-1724324 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.5" "Low lineage specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: " "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavourable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavourable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 14.3 14.9 17.2 23.7 26.9 39.7 13.0 35.2 32.7 12.5 16.4 14.3 6.1 29.2 16.5 8.5 12.1 12.6 10.2 10.2 19.4 8.4 11.7 12.5 19.0 20.3 22.6 9.0 16.2 12.9 12.2 27.5 12.9 17.1 14.4 14.6 11.6 12.7 10.3 21.5 15.1 34.9 13.1 26.0 24.2 15.7 16.4 25.1 14.9 14.6 7.6 22.4 13.5 15.2 7.4 11.8 33.5 6.3 4.4 5.5 1.4 16.1 9.7 7.0 6.4 9.2 7.4 6.9 15.9 7.1 7.9 9.2 12.2 14.8 17.2 9.7 4.6 12.0 6.5 8.2 6.3 13.1 10.4 15.3 18.3 10.9 6.1 17.1 22.1 8.5 5.6 6.9 4.5 13.6 17.9 14.4 6.6 9.1 7.9 13.4 9.7 8.3 14.5 10.7 8.3 6.4 7.3 7.8 11.3 13.9 16.4 19.1 11.0 7.1 13.8 12.5 12.1 5.6 8.8 20.1 14.6 21.6 4.2 13.9 3.9 16.7 6.3 7.7 5.5 3.4 4.2 6.2 4.7 4.2 2.0 7.4 4.7 4.0 33.5 4.4 3.7 11.8 4.5 1.4 17.2 26.9 35.2 32.7 19.4 8.4 22.6 9.0 17.1 25.1 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.7 10.8 6.5 6.1 4.8 5.4 6.1 7.9 6.7 10.9 8.1 13.3 5.4 12.4 7.0 8.3 14.2 13.0 10.0 10.5 8.1 11.2 13.4 7.4 10.3 4.7 18.3 9.4 5.8 6.9 13.2 10.5 6.6 22.7 8.2 6.2 4.1 14.9 4.7 6.8 4.9 9.9 14.1 7.0 4.1 10.5 7.0 4.5 10.1 85.6 6.9 11.0 7.9 7.1 9.9 7.9 6.9 10.2 6.7 4.8 17.5 7.0 7.8 6.4 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39949646-40099580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA059241: " "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 16.9 15.3 16.0 29.0 14.5 26.7 20.4 23.3 18.2 16.6 18.3 16.4 14.2 11.3 20.3 17.7 20.9 18.1 20.2 13.6 14.3 11.3 14.7 17.5 19.6 21.9 16.5 15.1 24.2 15.3 26.3 15.3 14.8 12.0 15.5 15.5 14.9 17.6 14.5 19.4 16.7 16.3 16.4 11.5 17.4 14.5 20.2 15.7 31.2 23.1 14.6 21.5 18.5 23.6 14.0 3.9 7.9 3.4 5.0 5.0 1.4 15.6 9.3 16.3 15.5 14.7 14.4 11.2 12.5 13.6 11.5 14.4 9.7 10.8 28.4 7.3 13.1 19.1 13.3 11.0 17.0 13.9 9.8 12.6 11.4 8.8 14.1 19.2 13.8 8.5 14.8 13.1 17.6 13.5 21.3 19.7 11.9 8.0 15.2 13.6 23.5 10.9 16.9 10.8 11.4 10.8 15.8 11.6 16.8 15.9 34.4 11.3 14.1 23.9 16.0 15.9 15.2 10.2 17.0 16.2 13.7 23.4 11.6 17.4 20.2 7.9 2.7 4.4 5.0 2.2 3.4 7.6 4.8 3.7 1.5 14.0 4.9 4.9 7.6 5.0 3.4 3.9 4.3 1.4 16.0 14.5 23.3 18.2 14.3 11.3 16.5 15.1 12.0 15.7 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 7.5;memory B-cell: 9.8;naive B-cell: 5.3;neutrophil: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 9.8;granulocytes: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favourable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavourable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 8.2 4.7 19.8 7.1 19.4 6.1 8.3 28.6 34.9 10.6 5.2 3.7 0.6 2.7 8.6 3.2 3.1 12.0 11.9 11.5 25.8 15.5 19.8 12.7 9.2 10.9 17.3 17.4 14.9 14.2 3.8 14.2 5.9 22.8 11.3 3.4 4.3 7.7 7.0 5.4 2.7 3.8 7.4 7.0 7.5 7.4 7.2 4.5 0.9 13.1 1.6 11.9 6.9 6.7 9.8 0.9 7.5 0.7 0.1 0.2 0.6 7.0 0.0 14.1 1.8 13.2 13.4 3.2 5.9 5.6 3.6 3.9 0.1 3.4 25.0 0.7 5.8 2.1 0.7 8.3 7.0 0.0 3.3 0.0 4.7 0.1 6.1 7.1 0.1 9.5 2.1 10.8 3.9 4.6 0.1 30.8 7.3 0.0 0.0 2.7 8.9 3.8 19.2 19.4 19.0 1.9 1.9 3.1 9.1 15.0 0.0 0.3 1.9 3.6 11.3 15.7 20.1 13.1 9.0 17.4 13.3 17.9 5.9 9.4 15.3 7.5 0.3 0.5 0.0 0.7 0.0 9.8 0.0 0.0 0.9 5.3 0.0 0.0 5.6 0.1 0.5 0.1 0.2 0.6 19.8 19.4 28.6 34.9 25.8 15.5 17.3 17.4 22.8 4.5 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2;ovary: 9.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.9;HBF TERT88: 18.2;HMC-1: 34.4;LHCN-M2: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 52 "basophil: 3.5;eosinophil: 6.9" "Lineage enriched" "Detected in single" 69 "granulocytes: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 1.3 0.2 0.1 5.2 0.1 0.0 3.7 0.3 0.1 3.4 2.3 0.1 0.1 0.3 4.1 20.2 1.1 1.0 4.2 0.3 0.1 0.0 0.4 0.1 3.3 0.1 0.1 0.1 9.8 0.2 0.0 0.5 0.1 0.1 2.0 0.7 1.4 0.6 0.3 0.7 1.1 3.0 3.9 0.1 0.1 1.1 2.5 0.1 0.1 0.2 1.2 1.2 1.6 1.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.7 0.0 3.1 14.6 5.5 11.9 0.0 1.5 0.0 0.0 1.3 0.0 0.0 0.0 18.2 0.0 0.0 1.0 0.0 0.0 0.2 0.0 34.4 2.0 0.0 1.5 0.7 0.0 0.0 0.0 10.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Uncertain "Plasma membrane,Microtubules,Cytosol" "Plasma membrane, Microtubules, Cytosol" "CAB016535: AB_785112, HPA000974: , HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 41.2 31.7 30.4 44.9 22.3 19.2 30.4 19.6 24.2 29.9 22.3 35.6 20.0 9.9 12.5 35.2 23.4 32.3 41.8 20.2 11.9 51.3 10.8 44.5 27.7 29.0 11.3 25.2 23.9 26.8 42.4 51.2 26.7 16.0 16.9 26.1 35.9 9.8 26.0 23.8 34.2 10.5 24.1 17.4 22.5 32.7 25.7 19.4 53.3 41.3 20.2 36.8 13.9 26.8 20.0 32.8 30.5 23.4 13.3 13.0 9.7 17.6 52.7 22.4 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400560 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 43.7;TIME: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavourable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 16.3 9.1 20.6 13.9 47.0 31.5 14.7 17.8 35.7 11.8 12.9 23.6 3.4 9.2 20.7 7.5 11.7 10.9 12.9 9.4 25.3 17.3 9.2 12.4 15.9 15.2 23.8 21.0 12.9 8.0 9.9 7.3 24.3 14.8 11.4 9.8 5.7 7.5 9.3 7.3 9.1 9.3 23.4 19.6 15.8 7.9 19.9 28.0 29.6 9.4 6.1 16.6 11.0 10.7 9.6 5.3 29.1 4.7 16.5 14.8 8.6 4.8 4.1 10.8 2.9 5.3 14.0 7.7 10.9 15.4 9.6 9.1 2.4 2.8 7.2 7.6 7.9 4.4 6.4 6.7 13.2 7.6 4.9 10.4 2.8 3.4 11.5 5.5 6.0 10.2 7.0 14.2 25.7 43.7 7.6 5.9 21.7 3.0 5.2 8.7 4.7 7.2 9.1 5.8 6.2 11.4 4.1 5.6 3.8 6.4 6.0 7.9 4.6 5.0 52.4 8.6 3.3 4.6 5.9 8.3 6.3 7.8 3.2 2.4 6.3 29.1 3.4 8.9 12.7 4.7 13.7 9.6 10.4 14.4 5.3 8.8 14.8 12.6 12.8 16.5 4.6 3.9 8.1 8.6 20.6 47.0 17.8 24.6 25.3 17.3 23.8 21.0 14.8 28.0 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504595-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;heart muscle: 58.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 20.9;HeLa: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favourable (2.81e-5)" 2.6 4.3 13.6 2.7 31.8 1.0 2.4 4.2 25.0 7.6 6.9 38.1 20.2 17.3 3.4 4.0 2.7 5.7 6.4 58.9 22.1 16.2 13.7 4.7 6.5 1.9 47.8 16.7 7.5 10.7 3.7 4.0 9.6 22.1 3.1 6.1 5.3 16.5 23.5 3.9 1.6 15.1 4.8 98.7 3.5 9.1 0.9 36.4 0.4 4.8 1.4 2.5 3.7 4.7 0.1 1.4 0.0 2.1 0.6 0.9 0.6 12.2 0.8 0.1 0.6 0.0 0.0 13.2 0.2 2.5 0.6 3.2 5.5 9.2 7.3 1.8 0.1 11.0 2.7 20.9 0.5 2.0 2.4 1.7 18.4 5.6 2.3 0.0 0.0 1.4 1.1 0.0 0.4 0.0 0.1 8.8 0.1 9.9 0.7 0.3 10.4 0.4 0.9 0.0 9.1 2.0 7.8 4.3 1.7 3.7 1.8 8.1 8.2 3.5 0.0 0.0 5.0 0.1 0.0 2.5 1.2 1.5 0.1 5.2 2.1 0.0 0.8 0.0 0.1 2.1 0.9 0.0 0.2 0.0 1.4 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.6 13.6 31.8 4.2 19.7 22.1 16.2 47.8 16.7 22.1 36.4 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007053 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA007053: AB_1846369" "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavourable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavourable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 5.3 3.3 18.1 6.1 29.4 9.7 6.0 13.8 21.3 6.6 6.3 31.1 2.4 4.8 9.6 3.7 7.8 5.3 7.8 4.1 20.8 10.1 6.3 4.6 6.2 8.0 22.1 12.9 9.7 3.1 8.0 4.1 10.5 14.4 25.8 6.1 3.4 4.5 5.9 3.2 7.9 5.9 7.1 20.8 7.0 6.5 16.4 26.3 6.1 5.8 1.3 8.4 5.9 6.4 1.3 1.8 8.5 2.2 1.3 0.8 0.6 3.6 3.8 13.4 16.2 7.3 10.5 7.0 11.6 12.4 4.4 5.8 4.8 4.0 9.1 4.2 8.2 2.1 5.1 2.5 10.1 11.3 3.0 15.6 5.7 5.6 4.4 6.3 11.7 7.2 5.5 6.0 9.3 4.3 4.7 12.8 9.4 5.8 8.4 9.4 1.3 2.6 9.1 6.9 3.5 5.1 6.6 6.9 12.8 8.9 7.2 10.4 2.4 23.2 4.8 9.2 4.9 18.6 7.1 1.4 1.8 7.9 9.7 8.5 9.5 3.3 2.2 1.5 0.8 1.2 0.8 1.1 0.7 0.7 1.8 1.3 0.5 0.7 8.5 1.3 0.7 0.9 0.8 0.6 18.1 29.4 13.8 21.3 20.8 10.1 22.1 12.9 14.4 26.3 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966769-55972784 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 105.5" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: " "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (9.94e-4)" "prognostic unfavourable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavourable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 10.7 7.6 4.5 20.8 6.5 18.7 11.5 4.2 4.3 12.6 11.6 3.5 6.0 6.1 10.7 6.4 13.6 10.8 12.6 10.1 5.4 2.2 8.3 16.7 19.5 12.2 6.0 2.0 14.2 8.3 5.2 4.2 49.0 7.3 10.8 9.1 51.2 9.3 9.9 10.8 14.6 9.3 11.8 5.0 12.5 10.1 7.8 5.1 39.3 9.5 10.7 14.7 16.7 10.1 9.3 10.8 5.2 3.9 4.5 7.6 4.3 16.5 8.9 19.6 10.9 4.0 5.2 36.2 20.6 10.8 25.6 24.0 18.7 15.9 15.7 15.5 7.6 10.6 14.9 9.0 26.1 18.5 14.6 18.1 14.8 7.1 1.3 14.3 13.1 2.7 2.3 17.3 6.0 12.9 17.2 14.3 17.8 12.7 29.6 12.1 7.8 13.3 29.0 18.9 11.8 7.4 16.2 8.1 10.5 23.5 8.6 105.5 18.6 10.5 7.2 17.7 17.2 13.6 15.0 8.2 9.4 19.6 10.0 10.5 15.2 5.2 3.6 3.1 7.0 3.9 7.0 9.3 3.2 5.0 2.7 6.1 3.0 5.3 1.7 4.5 1.6 10.8 7.6 4.3 4.5 6.5 4.2 4.3 5.4 2.2 6.0 2.0 7.3 5.1 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SCLC-21H: 14.4;THP-1: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.2" "Group enriched" "Detected in many" 7 "NK-cells: 7.2;T-cells: 5.0" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favourable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favourable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.6 16.2 10.8 2.4 13.0 1.6 4.1 8.7 17.1 8.7 5.0 6.1 5.1 5.3 7.2 6.0 2.8 19.5 5.6 3.0 8.6 10.7 8.2 3.2 4.0 2.0 5.8 14.3 9.5 4.8 7.6 10.8 3.1 9.3 6.1 3.4 7.7 3.6 8.6 2.1 3.6 7.6 5.5 3.1 1.6 3.7 17.7 5.2 0.8 6.8 1.2 1.1 6.3 3.0 0.1 0.8 0.4 0.8 7.2 5.0 1.3 2.3 3.0 2.4 7.6 1.7 2.4 1.0 2.1 4.2 5.8 5.4 0.7 3.5 0.0 3.3 3.5 3.1 0.0 2.1 2.4 5.9 2.4 0.0 1.9 0.0 7.4 2.8 3.3 1.9 4.4 9.2 3.8 0.0 0.3 0.0 1.7 7.0 1.9 0.8 1.9 1.1 0.0 0.0 0.1 7.4 2.0 14.4 4.0 2.5 3.0 3.6 3.3 21.6 0.0 2.6 1.0 0.5 2.4 3.8 3.6 0.0 9.3 1.9 2.7 0.0 0.7 0.4 1.3 0.8 0.5 0.0 3.0 1.9 0.7 0.1 5.0 3.2 0.1 7.2 0.7 0.8 2.7 1.3 10.8 13.0 8.7 17.1 8.6 10.7 5.8 14.3 9.3 5.2 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 4.1 3.7 2.7 4.7 2.4 5.5 4.7 4.2 2.4 4.9 4.8 6.5 5.6 5.7 4.0 5.0 4.8 2.6 2.8 3.0 5.9 13.0 5.3 5.5 3.0 6.7 5.9 4.2 8.3 5.0 10.3 5.3 5.2 4.5 0.9 14.7 9.1 4.1 3.9 8.8 5.2 5.6 8.2 5.4 3.8 5.1 1.2 1.8 1.5 1.5 1.7 2.7 1.6 4.2 7.7 11.5 6.0 6.8 8.0 23.9 5.2 3.4 5.9 5.5 6.0 8.8 6.3 4.6 4.5 9.7 9.2 3.9 3.8 3.2 14.8 13.2 15.3 6.0 5.6 4.6 13.5 7.2 8.5 5.2 4.2 6.4 5.8 4.5 3.7 10.7 5.3 20.4 5.7 8.4 9.9 5.0 5.9 5.4 14.0 8.3 22.4 3.5 11.3 2.5 15.5 9.3 5.4 15.9 9.4 6.7 5.5 9.5 7.1 5.9 4.8 4.7 3.9 0.0 1.5 0.0 2.1 1.0 0.2 1.2 1.6 1.2 1.8 0.3 2.7 0.5 1.5 1.7 0.6 1.6 2.7 1.6 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 125.1;LHCN-M2: 138.1;RH-30: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: " "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.3 10.8 14.3 12.7 13.1 11.5 9.5 5.4 17.6 23.8 19.8 15.4 8.9 13.6 9.7 8.4 7.2 19.7 125.1 18.1 6.7 9.1 12.7 7.3 10.8 15.4 14.4 8.8 11.3 9.2 14.6 16.8 15.3 13.5 11.7 138.1 13.5 13.7 11.7 16.8 11.0 12.4 434.6 12.6 7.4 14.7 12.9 12.1 9.5 7.2 14.4 9.6 17.5 6.9 11.2 10.5 12.6 10.9 5.8 9.5 20.9 10.3 13.3 13.4 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053812-151058530 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB008909: , HPA064535: " "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 4.5 11.3 24.4 6.9 30.4 6.1 5.3 13.6 36.1 5.3 6.1 6.7 4.5 7.9 4.5 17.4 6.5 5.0 6.2 5.8 25.0 19.7 9.0 7.7 5.3 6.0 15.4 15.4 3.2 5.8 8.9 7.9 5.3 20.8 5.8 6.3 3.2 6.0 6.3 5.7 6.5 6.2 6.0 8.6 5.2 5.7 3.1 7.7 6.8 6.0 3.6 6.9 6.7 3.1 6.6 21.5 9.0 21.7 9.5 14.9 10.6 11.6 14.0 13.1 21.3 14.5 10.7 6.5 7.7 12.8 15.2 12.6 9.9 10.9 11.5 27.7 9.5 8.3 21.0 11.8 7.0 9.1 12.5 12.6 12.3 9.8 9.6 10.2 23.7 11.5 8.8 12.5 3.9 10.2 12.8 8.4 15.2 22.6 27.4 20.8 14.4 22.1 13.4 5.4 12.8 13.2 8.8 8.3 35.7 11.1 13.7 14.6 6.4 9.0 8.6 15.0 3.9 11.2 14.4 19.6 21.4 4.5 23.6 14.7 26.8 7.8 19.0 9.0 6.9 21.7 5.4 6.6 6.8 6.8 21.5 5.9 5.1 6.2 2.8 9.5 16.4 12.8 14.9 10.6 24.4 30.4 13.6 36.1 25.0 19.7 15.4 15.4 20.8 7.7 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.6" "Cell line enhanced" "Detected in many" "MOLT-4: 91.7;REH: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavourable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavourable (2.33e-5)" 6.6 11.3 6.0 9.1 7.5 22.5 5.9 2.4 6.0 7.8 10.0 9.6 5.7 7.5 6.0 5.9 8.5 4.6 7.8 6.6 6.9 4.2 6.5 7.5 7.3 7.4 7.0 5.2 5.0 10.0 25.7 4.2 20.5 7.5 6.1 9.2 4.4 10.9 6.1 2.0 11.6 9.4 9.8 7.5 6.3 10.8 5.4 8.0 74.6 4.3 9.2 10.3 6.7 9.0 3.6 5.6 6.5 4.8 3.9 7.1 2.3 6.0 2.8 7.8 5.0 2.3 2.6 1.6 6.3 3.9 3.1 3.0 7.7 4.7 4.7 3.6 4.2 3.8 4.3 9.0 7.4 10.3 3.0 11.8 5.4 7.4 1.4 7.3 0.5 2.5 4.9 4.2 20.0 1.2 11.2 13.0 5.6 1.2 91.7 0.7 2.4 2.6 44.8 27.6 7.9 4.3 0.1 4.1 26.8 0.7 2.1 3.7 0.1 12.0 4.6 10.3 16.1 4.0 12.6 7.0 0.1 6.3 1.5 25.0 13.6 4.9 1.9 6.5 5.2 3.9 5.9 2.0 5.5 5.6 4.0 3.6 7.1 4.0 1.1 3.9 4.8 5.6 2.8 2.3 6.0 7.5 2.4 6.0 6.9 4.2 7.0 5.2 7.5 8.0 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932" Enhanced "CAB004364: AB_627243, HPA007932: AB_1078492" "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavourable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavourable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 7.9 12.9 10.9 6.2 15.2 44.1 14.0 10.8 14.7 9.4 12.7 6.0 6.3 15.8 9.4 8.6 23.4 18.5 16.5 8.1 11.5 9.3 13.8 10.6 10.1 8.8 7.6 9.7 7.7 9.1 3.3 16.2 22.9 11.2 11.2 14.8 6.6 13.2 6.5 15.9 15.4 9.8 12.1 9.2 7.9 13.9 29.0 7.8 12.1 20.0 15.6 15.5 10.7 11.7 15.6 15.0 22.4 11.3 12.4 15.3 7.8 3.7 7.8 1.8 0.5 2.4 11.6 14.7 6.5 7.7 10.8 17.5 16.7 1.9 2.8 10.2 1.7 2.5 1.4 2.8 5.9 1.3 7.0 0.4 8.2 7.9 0.4 6.7 3.2 14.3 13.9 9.0 2.8 13.6 10.4 4.5 4.9 0.7 4.1 14.8 1.7 7.5 6.7 0.4 1.1 1.6 1.0 0.6 6.5 1.5 5.8 3.4 11.6 0.6 2.6 0.1 3.2 0.9 5.1 4.8 8.4 3.7 0.8 4.0 0.8 7.3 10.9 22.4 8.6 11.3 14.8 12.4 12.9 15.3 15.0 15.6 11.1 13.2 10.0 12.4 8.0 11.2 12.8 7.8 10.9 15.2 10.8 12.7 11.5 9.3 7.6 9.7 11.2 7.8 CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26405238 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm Nucleoplasm "HPA044721: " "unprognostic (3.28e-3)" "unprognostic (2.25e-3)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (2.30e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (2.12e-1)" "prognostic favourable (9.23e-4)" "unprognostic (1.43e-2)" "unprognostic (1.88e-1)" "unprognostic (6.37e-2)" 7.6 8.8 10.1 10.4 8.5 5.2 5.6 26.9 11.3 5.9 24.0 6.0 13.8 13.8 11.2 6.5 10.0 7.0 11.2 7.6 8.3 7.3 9.4 10.4 6.7 5.2 7.8 7.9 6.1 12.7 8.4 10.2 10.6 8.2 7.8 11.2 4.6 9.0 19.2 9.7 6.1 15.0 12.7 6.0 6.4 11.7 16.3 9.9 12.8 6.4 6.9 7.2 15.5 11.0 1.9 1.7 3.4 1.6 1.0 2.1 1.3 6.8 5.6 11.4 11.6 6.0 7.5 7.0 13.2 9.1 9.8 7.1 16.3 9.6 7.3 5.8 6.8 8.4 13.1 8.9 12.4 16.8 7.2 13.8 4.6 5.6 4.2 21.6 7.9 5.4 8.5 7.4 12.4 7.1 21.4 0.0 8.8 7.3 16.5 10.2 9.1 7.0 10.4 11.3 5.0 5.7 6.4 9.7 5.7 5.6 10.7 9.7 3.8 9.9 7.3 6.3 8.0 11.5 7.1 5.6 9.9 13.4 3.9 9.1 7.4 0.4 0.9 3.4 1.1 1.6 1.9 1.0 1.5 2.1 1.7 1.9 2.1 1.7 0.0 1.0 1.2 1.0 0.6 1.3 10.1 8.5 26.9 11.3 8.3 7.3 7.8 7.9 8.2 9.9 CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" Nucleoplasm "Cytoplasmic bodies" "CAB004216: AB_627245, HPA006738: AB_1078493" "unprognostic (3.60e-1)" "unprognostic (1.71e-1)" "unprognostic (5.44e-3)" "unprognostic (1.04e-3)" "unprognostic (1.93e-1)" "unprognostic (3.97e-2)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.66e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "prognostic unfavourable (8.92e-4)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (8.78e-3)" 26.2 27.0 22.8 18.9 22.4 33.9 17.4 31.0 26.8 23.1 21.9 22.9 24.7 16.6 22.5 20.1 22.7 29.1 21.5 22.9 26.3 23.4 18.5 48.7 23.3 26.6 23.4 18.8 43.7 29.1 15.5 28.4 19.8 20.6 20.7 10.8 18.7 20.6 21.6 14.6 26.6 21.4 21.0 17.9 29.0 17.7 22.3 16.1 29.3 25.8 18.3 24.2 17.0 17.6 6.0 8.9 5.1 6.4 18.6 9.9 2.9 8.8 16.1 10.1 11.1 11.5 9.0 13.2 9.1 13.4 9.5 8.6 11.9 10.0 15.5 10.7 10.3 17.9 6.6 14.9 3.6 13.9 8.0 14.5 17.4 9.8 16.8 14.0 23.3 15.8 18.2 10.1 11.4 19.6 12.5 20.9 8.5 23.3 15.3 21.1 22.3 17.2 44.3 8.6 22.3 13.8 9.9 10.0 11.9 13.7 14.5 8.2 18.2 13.3 22.4 11.4 12.9 9.8 8.8 38.1 29.2 13.9 10.7 9.6 10.4 3.7 3.4 4.9 9.9 4.5 9.9 3.5 5.6 7.9 4.4 6.0 6.3 7.7 5.1 18.6 6.4 8.9 3.8 2.9 22.8 22.4 31.0 26.8 26.3 23.4 23.4 18.8 20.6 16.1 CDKAL1 FLJ20342 ENSG00000145996 "CDK5 regulatory subunit associated protein 1 like 1" Q5VV42 6 20534457-21232404 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" Transferase "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SCLC-21H: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057474 Uncertain Vesicles Vesicles "HPA057474: " "unprognostic (9.64e-2)" "unprognostic (7.23e-3)" "unprognostic (8.40e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (1.05e-1)" "unprognostic (1.51e-2)" "unprognostic (3.47e-2)" "unprognostic (4.25e-3)" "unprognostic (6.72e-3)" "unprognostic (1.61e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "unprognostic (5.79e-3)" "unprognostic (3.11e-2)" "unprognostic (1.75e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" 18.5 9.8 10.9 18.0 12.2 14.7 13.9 24.1 10.6 16.6 11.4 14.6 9.6 8.1 19.4 12.1 12.1 13.5 11.4 10.8 9.0 7.8 10.8 9.7 11.9 13.4 12.4 7.7 16.6 14.1 12.0 29.9 12.6 11.2 10.8 12.0 14.3 15.7 11.0 22.2 15.0 11.4 13.7 13.4 13.9 11.7 11.4 13.8 22.9 17.1 13.6 19.4 13.2 12.6 8.1 5.4 3.3 11.2 12.0 9.7 3.6 2.9 1.8 4.2 5.4 2.4 3.2 4.4 3.0 2.8 4.5 6.0 3.3 2.6 6.9 7.7 2.6 2.9 5.6 3.1 6.1 12.4 3.1 5.9 3.1 4.4 3.1 5.8 4.1 2.9 3.3 4.3 4.0 4.1 7.6 2.8 3.3 2.4 7.3 6.9 2.9 2.0 4.3 5.6 6.5 5.8 3.3 66.0 3.9 3.4 5.5 4.4 4.0 2.9 4.0 5.3 3.7 2.1 5.6 4.5 11.9 6.1 1.9 3.3 8.9 1.5 3.6 3.3 7.8 5.9 6.5 8.1 7.7 7.7 4.9 7.8 9.7 8.6 1.9 12.0 11.2 5.4 8.2 3.6 10.9 12.2 24.1 10.6 9.0 7.8 12.4 7.7 11.2 13.8 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50329404-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 16.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA059605: , HPA065919: " "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 7.1 2.1 7.5 1.8 5.1 0.9 3.0 2.7 20.2 14.1 5.9 1.6 2.5 8.4 12.1 2.3 2.6 16.4 2.6 2.9 7.1 2.4 18.8 1.1 4.3 3.0 2.0 12.3 10.5 2.0 1.4 1.4 4.9 2.9 4.0 5.7 1.6 2.5 8.4 1.7 3.0 3.0 7.7 3.1 3.7 2.0 1.9 1.4 1.3 5.0 6.1 2.1 7.0 5.6 5.7 1.3 6.0 2.5 3.8 6.7 2.6 6.0 4.8 0.6 2.4 6.5 7.8 0.3 2.1 3.8 2.2 2.5 1.9 5.7 0.4 2.6 4.6 4.2 0.9 0.6 2.5 6.6 2.3 6.4 2.1 1.7 7.3 5.8 3.5 1.7 3.5 4.5 10.0 8.4 2.6 2.6 1.0 0.3 1.9 3.1 0.7 2.3 0.7 2.8 1.8 6.9 2.3 1.1 1.3 2.4 16.5 0.6 0.2 4.9 2.6 5.7 2.9 5.6 4.7 0.8 0.4 0.4 0.9 6.1 6.9 6.0 2.5 4.4 6.3 2.3 6.2 4.6 4.4 6.7 1.3 5.7 3.4 3.7 1.4 3.8 0.3 1.2 4.1 2.6 7.5 5.1 2.7 20.2 7.1 2.4 2.0 12.3 2.9 1.4 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75578005-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.7" "Cell line enhanced" "Detected in some" "A-431: 5.6;HEK 293: 3.7;HHSteC: 4.3;RPTEC TERT1: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.7 2.4 7.1 1.2 11.1 0.7 1.2 7.7 13.2 1.7 2.0 6.2 0.0 1.0 1.7 2.3 2.3 4.1 1.4 1.3 5.1 6.7 11.8 0.7 9.2 1.3 7.1 7.0 3.8 1.6 5.7 8.9 0.7 12.5 2.0 2.4 3.4 1.2 2.0 0.7 0.9 0.9 1.5 7.4 0.9 1.5 27.7 6.1 0.0 6.9 0.0 2.0 1.1 0.9 0.4 0.0 0.2 0.0 0.0 1.6 0.1 5.6 0.7 0.3 0.0 0.3 0.3 0.0 0.3 1.7 2.4 1.9 0.5 1.2 0.1 0.9 0.1 0.8 0.0 0.5 2.2 0.2 3.7 0.0 0.2 0.0 4.3 0.0 0.1 1.4 2.1 0.4 0.8 0.1 0.0 0.4 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 8.1 0.3 3.0 2.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.4 1.6 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 1.2 0.1 7.1 11.1 7.7 13.2 5.1 6.7 7.1 7.0 12.5 6.1 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027751 Uncertain Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 2.5 2.7 7.0 2.2 7.1 1.6 2.5 7.0 8.5 2.6 2.4 5.9 5.5 2.3 3.9 5.3 2.6 3.7 2.6 6.6 6.1 6.5 4.5 2.8 2.2 2.5 8.0 4.3 3.0 2.4 3.2 6.5 2.2 8.6 2.8 2.6 3.9 2.0 3.2 7.5 2.7 2.5 4.6 8.4 2.7 2.2 33.4 9.3 1.3 3.9 2.1 3.0 2.8 2.2 1.5 2.7 1.0 1.1 1.4 4.0 1.3 1.0 2.2 3.3 2.2 5.6 4.8 1.4 3.0 2.7 1.4 3.3 2.0 1.5 2.8 1.9 1.9 0.9 2.7 1.9 2.7 3.0 2.1 1.5 2.4 3.4 3.4 0.6 1.0 2.2 4.9 4.1 1.3 1.3 1.5 1.2 3.6 1.1 2.1 8.3 2.2 1.0 3.6 1.4 0.8 1.8 1.0 5.0 1.5 2.2 0.6 3.6 1.9 1.7 1.0 2.7 0.6 3.6 1.0 3.4 4.5 5.4 4.1 2.2 2.1 0.0 0.9 1.0 0.9 1.1 4.0 1.5 1.4 2.5 2.7 1.0 3.8 3.8 0.2 1.4 0.4 1.6 2.3 1.3 7.0 7.1 7.0 8.5 6.1 6.5 8.0 4.3 8.6 9.3 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 3.2;testis: 7.9" "Cell line enhanced" "Detected in some" "HAP1: 1.8;HL-60: 4.9;RT4: 3.3;SH-SY5Y: 6.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.6;T-reg: 3.2" "Group enriched" "Detected in many" 25 "B-cells: 1.6;T-cells: 3.2" "Low region specificity" "Detected in many" HPA067895 Uncertain "HPA067895: " "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.3 1.1 0.3 0.0 0.6 0.0 0.3 0.1 0.7 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.5 0.9 0.2 0.0 0.4 0.1 0.2 0.3 0.3 0.0 1.6 1.2 0.4 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.3 7.9 0.3 0.1 0.1 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.3 4.9 1.1 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.2 3.3 0.6 6.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell line enhanced" "Detected in many" "A549: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.7;eosinophil: 2.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Supported Supported Nucleoplasm Nucleoplasm "CAB011577: AB_727019, HPA002847: AB_1080107" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (1.41e-1)" "unprognostic (1.25e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" "unprognostic (9.63e-3)" "unprognostic (2.05e-3)" "unprognostic (1.66e-1)" "prognostic favourable (5.54e-4)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.99e-1)" 3.3 3.2 8.0 1.8 24.7 3.2 4.3 3.9 28.0 5.4 2.7 7.7 1.8 1.5 4.5 2.8 5.2 2.8 3.1 5.0 8.0 3.7 6.3 2.2 6.9 1.4 3.5 13.2 6.7 4.5 6.2 5.0 5.4 5.9 6.7 2.2 2.0 3.9 4.4 3.0 3.5 1.9 4.0 5.7 2.3 4.9 14.0 5.7 1.6 5.1 0.8 2.1 5.6 4.6 0.7 1.0 7.7 1.0 0.5 0.6 0.2 1.7 12.3 3.5 3.1 3.3 4.5 2.5 2.0 3.8 2.8 3.2 4.0 2.3 1.9 0.4 1.3 0.5 4.0 3.0 5.9 0.5 2.6 0.0 7.1 3.1 1.6 0.1 0.8 2.6 3.1 6.8 7.1 1.3 0.1 1.9 4.2 1.7 0.8 0.8 7.1 3.0 0.7 3.8 0.1 2.4 8.9 0.7 4.4 4.5 1.1 2.2 1.6 0.7 7.3 4.3 1.9 7.9 1.5 0.3 0.1 0.3 2.4 0.5 4.2 7.7 1.0 2.1 0.6 0.6 0.3 0.2 0.4 0.3 0.3 0.7 0.6 0.6 4.7 0.5 0.6 1.0 0.2 0.2 8.0 24.7 3.9 28.0 8.0 3.7 3.5 13.2 5.9 5.7 CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84582979-84651338 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 48.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 20.6;hTCEpi: 25.8;SK-BR-3: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced Approved "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA036187: AB_10601797, HPA064546: " "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favourable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favourable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" 0.9 4.6 7.4 2.5 10.4 0.4 6.7 13.3 12.9 4.3 16.7 3.3 9.3 24.8 2.0 19.1 17.4 20.5 8.8 0.5 7.4 8.4 11.9 0.6 10.6 0.8 6.4 4.7 5.5 4.5 19.3 7.1 19.7 14.1 6.1 13.6 4.2 11.2 4.3 0.2 12.9 48.0 0.8 2.4 1.0 11.5 5.1 2.3 0.9 19.3 7.9 6.1 3.5 7.4 0.0 2.1 0.0 0.0 0.0 0.4 0.0 11.5 0.2 0.6 0.1 0.0 0.0 12.1 0.0 0.1 0.3 0.2 4.9 20.6 0.0 0.9 0.0 12.1 3.8 10.2 0.1 0.8 5.7 0.0 1.8 1.1 0.0 0.3 0.8 0.1 25.8 0.0 3.7 0.0 0.0 0.0 0.0 8.1 0.1 0.0 1.7 0.8 0.0 0.0 2.4 5.8 8.8 4.8 0.1 1.3 28.0 0.0 8.5 0.2 0.0 0.0 0.7 1.3 1.5 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.4 10.4 13.3 12.9 7.4 8.4 6.4 4.7 14.1 2.3 CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126786-5197887 "Enzymes, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/84: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum,Cytosol" 200000 "Endoplasmic reticulum" Cytosol "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favourable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" 14.8 16.1 22.2 9.9 25.5 12.1 12.1 36.0 34.5 12.7 11.8 21.4 6.7 5.9 12.9 9.8 10.5 12.5 10.0 26.6 22.0 34.0 16.9 14.2 14.5 10.9 26.7 24.0 10.9 7.2 20.6 15.6 11.1 28.3 15.9 12.3 19.8 8.0 19.7 9.4 6.2 9.9 20.2 16.2 9.8 10.6 13.0 12.5 8.1 14.2 4.6 13.6 11.6 8.2 7.6 7.9 28.3 9.7 6.5 11.1 11.7 9.4 10.6 10.6 5.5 6.3 5.8 4.9 5.2 10.7 8.6 12.5 6.5 9.3 7.2 2.6 9.7 13.6 8.6 10.9 9.2 7.6 3.0 8.3 3.0 10.0 5.9 5.4 3.1 5.0 6.1 11.3 4.4 11.5 4.0 9.3 8.0 1.6 10.6 2.0 5.1 3.2 9.2 8.6 3.3 5.5 9.2 4.4 6.2 5.8 9.9 13.4 6.1 2.5 8.4 6.2 4.9 5.5 5.2 8.1 59.6 6.0 2.8 4.2 3.7 24.1 9.7 11.5 10.0 8.0 10.6 7.6 10.2 11.1 7.9 7.4 8.0 7.8 28.3 6.5 7.3 6.3 11.1 11.7 22.2 25.5 36.0 31.6 22.0 34.0 26.7 24.0 28.3 12.5 CDY1 CDY1A ENSG00000172288 "Chromodomain Y-linked 1" Q9Y6F8 Y 25622162-25624902 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY1B ENSG00000172352 "Chromodomain Y-linked 1B" Q9Y6F8 Y 24045229-24048019 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2A CDY2 ENSG00000182415 "Chromodomain Y-linked 2A" Q9Y6F7 Y 18025787-18028597 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "epididymis: 3.8;testis: 6.0" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2B CDY ENSG00000129873 "Chromodomain Y-linked 2B" Q9Y6F7 Y 17877410-17880220 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CEPT1 ENSG00000134255 "Choline/ethanolamine phosphotransferase 1" Q9Y6K0 1 111139627-111185102 "Enzymes, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.47e-3)" "unprognostic (1.83e-2)" "prognostic favourable (4.96e-4)" "unprognostic (5.52e-2)" "unprognostic (1.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.54e-3)" "unprognostic (1.84e-1)" "unprognostic (9.20e-3)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "unprognostic (5.88e-2)" "unprognostic (1.27e-2)" 22.4 22.9 16.0 22.2 19.5 5.6 20.1 20.7 19.8 14.9 13.7 22.2 17.5 19.0 18.3 19.1 21.3 16.6 15.3 12.2 17.9 16.0 22.6 39.4 16.5 31.7 22.9 15.1 22.9 17.8 19.6 25.5 22.5 18.2 13.9 18.1 16.9 19.2 12.0 11.2 17.8 20.2 16.3 23.3 34.5 17.5 12.5 21.3 22.3 19.4 11.5 24.7 19.5 17.8 14.6 9.0 4.2 19.1 5.3 9.0 5.5 13.9 5.2 6.2 6.0 24.8 12.3 15.2 15.5 8.8 7.2 8.8 4.6 15.9 16.6 17.2 8.0 17.3 9.0 12.1 10.4 12.3 14.1 7.2 9.5 10.1 16.6 17.0 10.4 9.9 23.4 5.3 25.3 9.6 15.6 10.9 9.4 10.1 17.4 16.8 9.6 10.9 9.5 19.8 13.5 11.8 8.8 8.2 4.4 14.3 21.8 16.5 11.7 18.5 8.3 11.8 7.4 25.6 10.4 10.0 10.9 13.0 15.9 15.3 22.3 3.2 7.6 4.2 6.4 13.6 8.4 14.5 7.2 6.7 9.0 14.6 8.4 9.0 1.9 5.3 19.1 7.0 6.2 5.5 16.0 19.5 20.7 19.8 17.9 16.0 22.9 15.1 18.2 21.3 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684411-46738261 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles Vesicles "HPA064699: " "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavourable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favourable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavourable (1.58e-4)" 10.6 15.5 10.6 16.7 10.8 14.5 12.9 29.3 21.7 10.8 14.6 9.8 15.8 24.9 14.1 7.5 10.0 15.3 18.9 36.5 11.4 16.8 15.2 12.1 10.6 19.1 21.7 13.1 22.7 23.2 7.2 33.3 7.9 23.9 8.2 12.2 12.3 11.8 11.6 12.8 11.9 25.1 12.5 10.2 14.5 14.0 6.0 6.5 39.2 16.1 8.7 19.5 10.7 17.4 2.0 4.9 3.6 6.9 2.0 16.4 3.6 9.3 5.6 27.4 8.6 15.8 12.0 2.5 16.4 12.8 9.4 6.6 8.2 3.1 13.0 7.7 17.5 6.1 11.5 7.4 9.6 4.6 12.5 5.8 14.2 10.7 11.0 18.2 1.5 9.9 9.6 10.2 3.5 27.9 4.3 16.9 17.2 0.7 12.3 9.1 12.4 6.2 23.0 31.1 14.8 5.6 0.1 25.6 23.3 8.0 3.9 17.2 4.3 13.9 25.3 19.5 10.4 14.3 23.7 17.6 21.2 8.2 20.7 10.4 15.8 0.6 2.6 3.0 9.4 6.0 16.4 1.8 9.9 9.0 4.5 2.0 5.8 5.4 3.6 2.0 6.9 4.9 8.6 3.6 10.6 10.8 29.3 21.7 11.4 16.8 21.7 13.1 23.9 6.5 CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 25.6;skin 1: 29.0;testis: 37.9" "Cell line enriched" "Detected in some" 6 "hTCEpi: 37.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" 0.4 0.0 0.4 0.4 0.4 0.0 1.9 0.4 0.4 6.0 0.4 0.4 0.4 0.0 0.4 0.4 25.6 0.3 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 0.0 0.4 3.6 0.4 0.4 29.0 0.4 0.4 0.4 0.4 0.0 37.9 0.4 0.4 0.4 0.4 8.5 0.4 11.2 0.0 0.0 1.5 0.6 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.1 0.2 0.2 0.0 0.7 0.3 0.0 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129306-50167533 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026589 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA026589: AB_1852727" "unprognostic (1.59e-2)" "unprognostic (9.83e-2)" "unprognostic (5.17e-2)" "unprognostic (3.64e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-3)" "prognostic unfavourable (4.63e-5)" "unprognostic (5.56e-2)" "unprognostic (1.65e-2)" "unprognostic (9.26e-2)" "unprognostic (1.88e-3)" "unprognostic (5.67e-2)" "prognostic unfavourable (9.33e-11)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "prognostic favourable (5.76e-5)" "unprognostic (3.26e-1)" 18.0 13.2 18.3 13.3 21.6 10.9 18.0 38.3 19.6 21.1 15.0 17.5 8.9 6.3 22.6 20.9 14.1 17.7 14.9 9.9 16.7 11.6 16.0 7.8 14.7 15.1 13.9 19.1 22.5 13.8 23.9 22.4 19.7 14.3 15.6 11.5 14.9 14.6 16.2 5.0 21.5 12.2 21.8 10.3 15.7 13.3 11.6 14.4 12.7 15.5 7.0 14.9 18.4 18.3 21.0 26.1 33.5 35.1 29.0 26.3 22.3 9.3 10.4 23.0 6.5 12.9 10.8 19.5 20.6 17.8 19.8 18.8 24.5 14.7 14.1 17.2 29.1 8.7 10.1 7.9 19.6 22.1 10.3 11.8 8.8 14.8 25.6 11.9 16.0 18.6 12.0 16.3 15.2 18.0 8.8 13.1 24.8 16.2 10.4 32.5 14.8 10.1 13.6 15.1 10.0 25.6 12.0 7.0 11.4 17.4 8.2 27.5 11.2 13.8 17.1 17.0 11.4 12.8 8.9 12.8 12.1 11.3 13.5 8.3 7.8 24.8 19.0 28.1 26.0 25.5 22.9 17.9 22.9 22.4 18.2 21.0 17.9 24.3 33.5 29.0 35.1 26.1 26.3 22.3 18.3 21.6 38.3 19.6 16.7 11.6 13.9 19.1 14.3 14.4 CGAS "C6orf150, cGAS, MB21D1" ENSG00000164430 "Cyclic GMP-AMP synthase" Q8N884 6 73413515-73452276 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 32.0" "Cell line enhanced" "Detected in many" "RH-30: 21.2;RPMI-8226: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA031700, HPA031702" Enhanced Approved "Centriolar satellite,Cytosol" "Centriolar satellite" Cytosol "HPA031700: AB_10601693, HPA031702: " "unprognostic (2.49e-1)" "unprognostic (2.36e-1)" "unprognostic (4.61e-2)" "unprognostic (4.95e-2)" "unprognostic (2.49e-2)" "unprognostic (1.81e-1)" "unprognostic (4.84e-3)" "unprognostic (1.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.25e-2)" "unprognostic (2.20e-2)" "unprognostic (2.77e-1)" "prognostic unfavourable (2.27e-7)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-1)" 6.5 2.0 2.9 10.5 4.5 18.5 8.1 1.2 3.9 4.7 3.7 3.4 2.1 4.1 5.5 2.8 5.3 3.9 4.3 3.2 2.8 2.9 2.5 1.9 9.6 11.8 7.2 0.6 3.4 3.8 2.3 1.8 4.8 4.4 6.6 3.1 2.2 4.2 2.9 1.9 1.8 5.2 3.6 4.7 12.8 3.5 1.7 4.3 6.2 3.9 4.2 15.5 6.6 32.0 6.3 12.5 13.3 12.9 3.0 6.0 3.9 8.8 3.0 0.0 0.1 0.6 1.3 0.0 4.4 1.9 5.8 6.4 9.8 6.7 0.1 9.7 2.1 4.6 4.9 0.0 6.2 14.7 0.0 7.7 3.8 0.0 2.1 5.9 5.4 0.8 1.6 5.7 0.0 1.7 0.0 18.4 4.2 3.6 0.0 13.4 2.9 5.4 11.5 21.2 22.3 0.0 3.7 0.1 0.0 7.8 0.2 4.6 0.0 16.0 2.0 0.0 4.3 3.9 0.1 4.0 8.7 0.1 0.0 8.5 5.8 13.3 9.2 13.2 4.6 12.9 3.6 6.3 6.0 4.6 5.4 4.8 1.4 2.6 5.8 3.0 7.8 12.5 5.8 3.9 2.9 4.5 1.2 3.9 2.8 2.9 7.2 0.6 4.4 4.3 CHAT ENSG00000070748 "Choline O-acetyltransferase" P28329 10 49609095-49665104 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Acyltransferase, Transferase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;placenta: 10.4" "Cell line enriched" "Detected in some" 11 "NB-4: 15.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "basal ganglia: 5.4" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 18.4" "Group enriched" "Detected in many" 4 "basal ganglia: 7.7;pons and medulla: 8.1" "CAB002313, HPA048547, CAB079053" Supported Supported "CAB002313: AB_563661, CAB079053: , HPA048547: " "unprognostic (2.34e-2)" "unprognostic (6.10e-2)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (2.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.09e-1)" 0.2 0.0 0.2 0.3 5.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.2 1.6 0.2 0.5 0.2 0.0 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.9 0.0 0.2 10.4 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 1.1 0.2 0.4 0.2 0.0 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.6 1.0 0.3 0.2 0.6 1.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 15.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 1.3 0.0 0.0 0.2 0.3 0.4 0.1 0.5 0.3 1.0 0.4 0.1 0.6 0.5 0.3 0.0 0.6 0.1 1.0 0.2 0.0 0.2 5.4 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA044364: " "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favourable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavourable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavourable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 12.7 10.4 23.4 14.2 4.8 10.3 10.2 17.9 8.6 11.5 12.4 25.4 28.3 33.4 18.5 7.0 15.4 14.3 9.4 14.2 20.9 6.6 61.9 8.7 13.0 1.5 31.6 11.8 5.3 2.0 14.5 10.3 13.6 31.3 29.4 15.1 6.6 46.9 15.5 23.7 9.4 28.6 21.9 17.5 10.6 17.0 14.8 15.7 14.7 10.2 4.3 27.5 10.3 9.1 16.6 14.1 8.0 16.4 6.6 11.8 47.6 6.1 23.8 19.4 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.7 4.7 13.5 16.7 3.8 19.2 8.7 7.3 8.6 9.7 14.2 12.0 10.1 17.4 6.2 5.1 14.2 20.5 13.4 11.3 12.4 15.7 22.9 9.0 19.8 3.8 14.5 16.8 8.1 6.2 12.4 11.0 10.7 13.8 15.2 9.0 20.7 11.6 23.3 19.0 12.0 25.3 9.2 20.3 6.0 6.1 7.9 4.5 8.1 14.5 8.0 9.9 13.4 3.7 7.8 9.3 6.8 3.8 9.2 16.2 34.0 7.4 15.2 9.9 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: " "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-1)" "unprognostic (2.14e-3)" "unprognostic (6.56e-4)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "prognostic unfavourable (4.21e-9)" "unprognostic (5.03e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.11e-2)" 13.7 11.4 14.1 19.0 15.0 25.8 12.5 20.0 16.9 12.1 15.2 16.5 13.4 19.0 15.6 16.7 21.6 12.6 14.3 13.7 12.5 9.8 12.8 13.4 17.0 21.7 15.1 12.6 9.6 16.8 9.6 20.6 22.9 13.0 14.3 12.8 15.5 13.9 14.7 21.0 16.7 18.7 17.8 15.1 24.9 16.8 19.2 14.2 22.3 13.5 12.7 18.4 18.6 14.2 6.6 12.1 19.7 17.0 12.3 12.5 10.1 4.4 10.8 9.1 0.8 8.0 10.7 17.0 9.1 7.6 9.7 10.1 8.5 3.8 0.1 8.8 10.6 7.1 1.1 9.2 5.6 0.6 9.6 14.4 7.4 8.6 17.5 0.6 25.0 14.4 8.4 8.8 6.6 11.8 6.1 0.0 6.7 14.8 10.4 11.2 10.9 8.6 1.4 1.3 4.4 6.4 20.9 8.9 11.4 7.5 7.7 7.0 13.8 14.9 13.2 0.6 2.2 5.0 3.3 15.9 0.0 2.1 0.0 3.0 8.7 17.6 14.2 19.7 10.8 16.9 10.0 6.6 8.7 11.6 12.1 4.5 8.3 9.1 18.9 12.3 17.0 6.6 12.5 10.1 14.1 15.0 20.0 16.9 12.5 9.8 15.1 12.6 13.0 14.2 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavourable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 8.9 15.5 18.1 6.4 19.5 25.5 18.6 10.2 19.3 10.8 18.2 30.9 28.8 19.0 5.8 19.2 3.9 6.5 10.7 5.4 18.7 15.4 8.0 17.4 11.4 7.5 26.5 12.5 10.4 29.3 9.2 10.0 5.0 21.5 13.5 11.8 17.4 36.9 37.4 3.9 4.2 22.8 8.2 20.9 13.5 18.8 55.9 22.7 3.1 19.9 2.2 5.2 8.7 4.7 1.3 1.5 9.5 2.5 1.6 0.7 0.4 7.9 7.0 8.1 7.8 2.8 1.9 8.3 2.6 4.2 7.2 4.7 29.9 22.7 6.2 9.5 3.7 5.3 11.4 1.8 5.5 2.8 4.0 7.6 9.1 34.6 7.9 8.1 4.2 3.8 3.1 3.3 1.6 4.0 7.2 10.7 3.8 6.2 4.3 22.0 13.2 4.7 6.9 8.6 17.3 6.0 9.0 6.0 6.4 4.9 24.9 57.4 10.6 11.1 2.3 4.5 5.7 10.9 3.3 12.6 12.9 10.8 5.0 10.6 4.2 0.0 1.4 9.5 0.2 2.5 0.0 1.3 0.1 0.4 1.5 0.6 0.7 0.5 0.8 1.6 1.5 1.2 0.3 0.4 18.1 19.5 10.2 19.3 18.7 15.4 26.5 12.5 21.5 22.7 CHKB "CHETK, CHKL" ENSG00000100288 "Choline kinase beta" Q9Y259 22 50578949-50601455 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Congenital muscular dystrophy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018797 Approved Approved Cytosol Cytosol "HPA018797: AB_1846666" "unprognostic (6.03e-4)" "prognostic favourable (4.66e-4)" "unprognostic (4.31e-2)" "unprognostic (2.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (3.25e-3)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (7.84e-2)" "unprognostic (5.23e-3)" "unprognostic (5.43e-2)" "prognostic unfavourable (1.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.54e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-3)" 14.1 13.6 12.7 18.9 14.4 14.8 13.0 21.3 13.4 12.9 15.1 13.8 10.4 9.8 10.1 12.5 10.7 16.2 13.6 10.6 10.7 6.8 14.3 9.3 12.6 8.7 14.7 6.1 9.1 8.4 21.9 19.2 12.3 12.7 11.7 6.9 12.8 13.4 12.5 7.8 10.5 16.9 8.0 9.5 18.5 14.8 19.9 15.8 8.5 14.5 6.6 16.5 12.1 10.9 13.6 21.2 15.0 23.9 20.6 18.6 19.5 3.6 1.0 3.0 1.1 3.1 2.1 10.1 4.3 8.6 1.8 2.4 0.0 1.4 1.8 3.3 0.0 1.7 1.5 0.9 0.3 1.5 4.3 2.4 2.2 0.8 14.4 2.9 6.1 0.9 5.3 0.7 3.6 9.0 1.2 4.7 4.8 3.3 2.6 8.2 0.5 0.6 3.3 0.4 10.1 3.9 2.5 1.4 4.2 3.4 3.4 3.0 1.2 1.8 2.7 1.7 3.6 1.6 1.2 7.7 0.7 2.3 2.9 2.2 1.7 5.7 23.9 15.0 16.3 21.9 15.5 12.9 15.2 17.3 21.2 13.6 14.4 13.3 5.7 20.6 14.2 19.5 18.6 19.5 12.7 14.4 21.3 13.4 10.7 6.8 14.7 6.1 12.7 15.8 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538947-219543787 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 11.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavourable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavourable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavourable (2.96e-4)" 8.6 14.1 9.7 8.4 11.8 1.4 6.8 8.5 19.4 22.1 8.6 11.3 23.0 18.4 17.0 24.6 7.9 9.2 17.1 36.3 12.2 10.7 11.3 52.1 11.6 5.4 9.0 10.5 38.1 60.7 16.3 36.9 62.7 10.4 19.3 3.8 27.4 31.6 19.9 4.3 9.0 13.3 9.1 8.3 4.5 15.6 34.2 7.0 3.8 17.9 7.4 10.6 11.9 8.5 1.3 11.1 6.9 0.1 2.1 3.0 0.8 18.5 3.7 2.7 23.2 10.6 16.6 31.8 18.9 16.0 5.4 4.9 10.3 16.4 5.8 40.7 18.2 23.8 1.8 11.4 0.8 8.9 6.4 2.0 5.2 44.5 14.8 1.8 12.2 22.3 20.1 5.4 5.2 0.0 12.9 14.2 5.1 29.2 0.2 4.8 11.5 14.3 0.0 8.8 11.3 6.4 8.4 6.8 10.4 9.1 8.8 25.8 3.0 6.3 0.4 19.9 10.9 23.7 9.8 17.1 5.3 2.6 18.2 1.8 20.0 2.1 0.0 6.9 2.4 0.1 3.0 1.3 1.9 1.6 0.0 0.1 2.2 0.8 0.0 2.1 0.0 11.1 1.2 0.8 9.7 11.8 8.5 19.4 12.2 10.7 9.0 10.5 10.4 7.0 CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232489-151238827 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "HPA020992: AB_1847267" "unprognostic (8.31e-2)" "unprognostic (2.14e-3)" "unprognostic (1.02e-3)" "unprognostic (1.14e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "prognostic unfavourable (9.47e-4)" "unprognostic (4.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "prognostic favourable (2.51e-4)" "unprognostic (1.04e-1)" "unprognostic (2.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (8.59e-3)" 13.5 29.3 13.4 19.0 12.9 22.6 19.1 13.1 20.2 15.3 14.4 11.4 20.7 14.9 19.5 16.9 13.3 14.9 17.6 18.8 13.7 12.5 14.9 20.7 17.4 23.4 11.4 17.4 14.4 23.7 16.7 41.5 18.6 11.8 18.5 10.8 12.2 25.4 19.8 7.9 14.2 17.1 17.3 9.4 28.1 20.1 12.9 11.1 16.2 17.5 7.4 13.7 18.9 12.8 2.7 9.5 9.9 5.6 2.6 5.7 3.7 8.9 7.3 4.9 14.4 17.2 17.1 7.5 18.9 29.6 10.3 12.6 4.8 15.3 2.7 33.5 30.0 11.3 2.2 13.5 4.5 10.3 6.7 2.8 8.0 6.7 16.2 5.8 24.0 26.2 7.6 9.7 3.5 16.2 2.7 7.9 16.3 14.7 5.4 22.7 6.6 8.5 5.1 2.9 9.0 10.0 7.1 5.4 9.5 10.1 10.0 4.8 3.8 9.6 22.0 11.5 1.9 15.2 16.0 14.6 2.1 3.9 41.7 7.8 15.5 1.2 5.6 7.9 5.7 5.1 5.4 2.7 3.1 5.1 6.3 2.7 2.2 2.3 9.9 2.6 5.0 9.5 3.4 3.7 13.4 12.9 13.1 20.2 13.7 12.5 11.4 17.4 11.8 11.1 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 19.4;eosinophil: 9.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favourable (7.41e-4)" "unprognostic (1.79e-1)" 18.0 21.6 19.3 14.3 20.4 21.4 76.7 12.8 16.7 22.2 40.0 11.0 15.8 36.5 9.3 25.0 10.9 14.7 17.1 71.4 18.5 14.5 30.6 64.6 20.2 30.5 17.8 14.5 11.3 14.2 12.6 7.6 9.6 12.8 16.3 21.0 14.0 53.1 22.8 18.5 13.5 42.9 16.7 17.4 13.0 23.1 28.3 12.6 3.3 26.0 7.4 8.7 17.7 38.7 3.0 2.5 19.4 1.5 3.3 0.8 0.4 3.4 16.3 4.4 9.4 35.2 11.8 12.6 12.7 14.6 12.8 8.3 6.0 2.4 5.3 7.2 17.2 5.3 26.6 4.4 12.2 8.0 22.5 21.6 8.7 35.0 19.7 10.6 4.4 11.1 1.3 5.7 10.6 6.3 31.3 13.8 12.5 8.5 6.3 36.8 11.7 21.6 4.9 8.6 3.8 5.8 13.7 4.3 3.3 11.7 16.9 31.5 17.2 7.3 4.6 11.7 6.1 9.1 12.3 7.9 2.4 6.5 9.2 12.4 17.0 19.4 1.5 9.7 0.4 1.2 0.4 3.0 0.8 0.7 2.0 2.0 0.3 0.4 2.2 3.3 1.4 2.5 0.4 0.4 19.3 20.4 12.8 16.7 18.5 14.5 17.8 14.5 12.8 12.6 CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45648877-45665622 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.5" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 10.1;TIME: 9.6;WM-115: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "unprognostic (1.77e-2)" "unprognostic (1.67e-1)" "unprognostic (6.37e-3)" "unprognostic (1.32e-1)" "unprognostic (2.18e-2)" "unprognostic (2.50e-1)" "prognostic unfavourable (3.95e-4)" "unprognostic (6.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "unprognostic (2.10e-1)" "prognostic unfavourable (4.64e-7)" "unprognostic (5.37e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" 2.2 8.6 21.2 2.0 21.5 1.2 4.8 2.3 42.5 2.2 1.6 5.0 0.0 1.9 2.5 1.2 1.3 6.5 2.1 2.8 18.6 15.5 2.6 1.5 2.5 2.0 13.6 17.0 4.4 2.5 17.7 4.9 1.7 10.6 1.4 1.2 1.3 14.8 1.6 3.6 1.7 1.7 2.0 2.5 4.7 1.9 3.2 5.5 0.1 9.0 0.4 1.7 2.3 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 2.2 0.0 0.0 0.3 10.1 0.0 0.0 0.9 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.5 0.2 0.0 9.6 1.9 2.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 21.5 2.3 35.8 18.6 15.5 13.6 17.0 10.6 5.5 CHST11 "C4ST, C4St-1, C4ST1, HSA269537" ENSG00000171310 "Carbohydrate sulfotransferase 11" Q9NPF2 12 104455295-104762014 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052828 Approved Approved "Golgi apparatus" "Intracellular and membrane" 22000 "Golgi apparatus" "HPA052828: " "unprognostic (6.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.28e-2)" "unprognostic (7.53e-2)" "unprognostic (3.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.64e-3)" "unprognostic (9.21e-3)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (1.22e-2)" "unprognostic (5.44e-2)" "prognostic unfavourable (7.59e-11)" "unprognostic (1.64e-2)" "unprognostic (5.60e-2)" "unprognostic (5.40e-3)" "prognostic unfavourable (8.42e-4)" 6.7 14.3 14.6 21.6 16.6 37.3 4.9 5.7 16.1 6.6 6.2 8.2 9.7 3.9 15.7 16.1 4.4 5.2 11.1 6.6 13.4 11.9 4.4 4.0 15.3 22.5 11.5 6.7 8.7 6.3 1.9 6.8 17.2 10.0 6.4 5.2 16.1 3.3 13.4 1.7 2.7 7.7 12.6 10.5 17.5 8.3 3.3 11.8 26.5 4.3 2.9 15.6 8.5 5.3 2.0 2.6 13.8 1.3 1.3 2.8 0.6 13.5 6.3 2.9 1.8 7.4 3.6 10.3 1.3 0.4 0.6 0.5 0.0 17.8 0.0 2.0 1.8 3.4 1.7 7.1 0.7 0.1 2.5 18.1 1.6 0.0 1.1 21.0 21.5 1.3 1.0 11.6 1.9 4.5 27.9 4.6 1.2 3.3 16.1 24.9 2.4 2.3 18.3 9.7 4.5 6.0 0.1 4.9 8.0 0.8 9.2 17.1 2.7 21.4 10.4 2.0 2.2 10.4 11.2 24.1 25.9 3.4 9.4 14.8 20.2 9.3 1.3 9.4 2.8 1.2 1.6 0.9 1.5 2.1 0.7 2.0 0.7 1.8 13.8 1.3 1.1 2.6 2.8 0.6 14.6 16.6 5.7 10.4 13.4 11.9 11.5 6.7 10.0 11.8 CHST12 "C4S-2, C4ST2" ENSG00000136213 "Carbohydrate sulfotransferase 12" Q9NRB3 7 2403560-2448483 "Enzymes, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 25.6;NB-4: 26.5;U-266/70: 37.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041680 Approved Approved "Golgi apparatus" 430000 "Golgi apparatus" "HPA041680: AB_10959789" "unprognostic (4.12e-2)" "unprognostic (3.56e-1)" "unprognostic (3.04e-3)" "unprognostic (1.59e-1)" "unprognostic (2.05e-3)" "unprognostic (7.15e-2)" "unprognostic (2.01e-3)" "unprognostic (1.34e-1)" "unprognostic (3.20e-2)" "unprognostic (4.88e-2)" "prognostic favourable (1.32e-5)" "unprognostic (9.61e-2)" "unprognostic (1.66e-3)" "unprognostic (4.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" 24.2 12.0 9.4 12.1 10.5 14.5 11.2 17.8 16.5 11.9 10.1 13.2 9.0 13.5 14.4 10.6 5.9 11.7 10.9 12.0 8.8 7.7 9.3 6.8 13.6 10.3 10.4 9.2 9.6 17.5 4.9 14.4 9.6 12.7 11.8 4.2 12.3 14.1 11.6 11.9 11.5 10.1 8.1 9.5 25.0 12.4 10.2 8.6 9.0 11.2 4.4 11.8 10.6 10.3 5.7 21.0 16.4 3.5 37.4 30.2 6.7 3.8 4.0 2.4 4.4 3.7 2.7 12.5 7.0 3.3 3.1 4.2 4.4 1.5 3.4 13.4 3.1 3.2 1.5 1.9 0.8 4.5 8.3 2.3 3.4 4.9 1.7 7.8 25.6 3.6 1.1 2.7 0.3 3.2 6.1 12.4 1.4 3.6 8.2 26.5 8.4 7.2 3.1 3.2 17.9 1.5 2.1 3.0 12.2 3.4 2.6 1.7 3.2 10.0 5.3 4.5 11.8 8.8 6.2 37.9 14.6 1.5 3.6 4.0 7.8 15.5 3.5 16.4 30.2 2.8 18.9 5.2 10.7 24.5 6.6 5.7 4.5 13.5 1.0 37.4 1.2 21.0 10.2 6.7 9.4 10.5 17.8 16.5 8.8 7.7 10.4 9.2 12.7 8.6 CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524283-126543291 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood: 46.8;liver: 42.5" "Group enriched" "Detected in some" 8 "CACO-2: 12.2;Hep G2: 21.9;NB-4: 14.6;THP-1: 8.5" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 4 "eosinophil: 46.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 46.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (6.42e-4)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (8.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (5.16e-2)" "unprognostic (6.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-2)" 0.5 0.2 0.2 0.5 0.3 0.9 0.0 0.2 0.6 0.1 0.9 0.1 0.0 0.8 0.0 1.1 0.1 0.1 0.2 1.1 0.2 0.1 2.6 42.5 0.6 0.6 0.3 0.2 0.4 0.0 0.0 0.0 0.4 0.4 0.2 0.2 0.6 0.5 0.1 0.3 0.0 1.8 0.0 0.3 2.9 0.6 9.7 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 7.0 46.8 10.6 0.0 0.0 3.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 21.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 10.6 46.8 0.0 6.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 9.8 0.0 5.2 0.0 0.0 3.6 0.2 0.3 0.2 0.6 0.2 0.1 0.3 0.2 0.4 0.1 CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470998-40474571 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved Vesicles Vesicles "HPA057697: , HPA071601: " "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" 10.3 7.9 7.1 7.5 6.9 2.3 22.7 6.5 7.4 14.9 7.9 6.0 13.8 3.6 17.5 11.1 6.5 12.3 14.1 12.6 5.5 2.9 8.1 9.6 15.9 20.9 8.1 4.5 18.8 11.6 10.2 11.4 22.4 7.1 10.7 3.8 9.8 12.7 17.2 5.5 6.8 7.1 13.3 5.9 10.5 7.3 9.2 6.3 7.5 12.4 8.3 6.1 12.1 18.2 2.1 3.4 8.0 1.9 5.5 4.0 1.1 11.0 7.3 11.7 31.6 18.4 14.3 18.3 10.9 20.8 19.4 18.4 8.8 5.6 1.8 16.7 18.5 19.1 10.4 6.1 9.1 13.2 6.1 5.7 7.8 8.4 10.0 2.4 14.8 17.4 5.1 6.8 5.2 17.0 5.5 6.6 14.4 8.4 4.0 12.7 7.5 8.5 11.1 14.9 3.2 13.0 5.7 8.5 13.0 9.6 10.8 3.6 15.7 10.2 13.8 32.9 12.2 10.3 10.8 13.4 9.2 5.1 14.8 8.4 23.6 8.0 1.9 3.6 4.0 1.9 1.1 0.5 2.0 3.4 3.4 2.1 1.8 1.4 0.3 5.5 0.9 1.2 1.3 1.1 7.1 6.9 6.5 7.4 5.5 2.9 8.1 4.5 7.1 6.3 CHST15 "BRAG, GALNAC4S-6ST, KIAA0598" ENSG00000182022 "Carbohydrate sulfotransferase 15" Q7LFX5 10 124007666-124093607 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 27.1;REH: 35.6;U-266/70: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 29.4" "Group enriched" "Detected in many" 10 "granulocytes: 29.4;monocytes: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017584 Approved Approved Centrosome,Cytosol 560000 Cytosol Centrosome "HPA017584: AB_1849437" "unprognostic (1.19e-1)" "unprognostic (2.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (4.12e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-2)" "unprognostic (2.40e-2)" "unprognostic (7.62e-3)" "unprognostic (7.90e-2)" "unprognostic (8.16e-2)" "prognostic unfavourable (2.22e-7)" "unprognostic (6.47e-3)" "unprognostic (7.80e-2)" "unprognostic (4.63e-3)" "unprognostic (5.26e-3)" 16.4 10.0 8.7 17.0 20.6 5.7 10.7 3.4 17.9 9.8 15.4 6.6 4.0 8.8 8.6 10.8 11.3 13.1 11.7 6.4 11.3 5.3 9.0 11.9 13.9 35.4 6.5 9.6 35.0 12.6 2.9 7.7 5.9 9.2 8.5 8.3 14.4 8.2 13.4 11.0 8.3 12.5 9.5 9.0 31.5 11.4 4.8 8.7 2.8 19.3 6.1 12.6 12.5 12.0 2.1 2.0 29.4 15.4 0.0 0.1 3.2 12.6 8.5 3.2 0.7 3.1 1.7 0.0 2.6 3.5 1.4 2.0 0.2 6.9 0.0 8.3 10.5 14.4 0.6 8.3 1.2 0.0 2.4 0.0 3.9 6.3 1.0 0.0 16.3 1.0 9.6 3.9 3.3 2.8 0.0 27.1 6.9 7.0 0.0 0.0 2.8 0.0 35.6 4.3 8.4 7.0 1.2 0.3 0.7 6.8 3.9 0.0 2.8 0.0 3.3 0.3 0.1 10.0 0.4 24.6 5.9 6.8 0.1 0.0 0.0 0.0 8.8 6.2 0.0 14.0 0.0 2.0 0.0 0.0 1.8 2.1 0.1 0.0 29.4 0.0 15.4 2.0 0.1 3.2 8.7 20.6 3.4 17.9 11.3 5.3 6.5 9.6 9.2 8.7 CHST3 "C6ST, C6ST1" ENSG00000122863 "Carbohydrate sulfotransferase 3" Q7LGC8 10 71964365-72013564 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-251 MG: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047523, HPA055704" Enhanced Approved "Golgi apparatus,Cytosol" 510000 "Golgi apparatus, Cytosol" "HPA047523: , HPA055704: " "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "unprognostic (1.13e-3)" "unprognostic (1.16e-3)" "unprognostic (2.44e-1)" "unprognostic (4.67e-2)" "unprognostic (4.79e-2)" "unprognostic (7.53e-2)" "unprognostic (7.99e-2)" "unprognostic (3.71e-2)" "unprognostic (2.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.40e-2)" "unprognostic (2.65e-2)" "unprognostic (7.77e-2)" "unprognostic (2.56e-2)" "unprognostic (2.54e-3)" 22.2 11.6 9.2 7.0 19.4 0.7 12.0 2.9 11.6 10.4 9.0 19.4 4.8 1.7 13.7 7.4 8.4 13.6 6.2 11.9 11.3 5.1 8.6 1.8 6.3 2.2 30.1 5.5 25.0 6.1 1.9 4.0 10.0 15.6 10.7 3.3 5.7 6.3 19.5 13.6 7.1 4.0 21.0 16.2 2.9 11.6 19.4 25.2 0.5 7.3 4.8 2.2 7.5 18.5 0.2 0.3 0.8 0.1 0.1 0.2 0.0 6.7 7.3 3.8 9.3 17.3 6.8 0.1 14.4 13.9 8.9 5.9 6.4 13.7 0.0 10.0 17.0 8.9 3.3 9.9 7.1 0.2 2.5 0.0 12.8 6.1 8.8 0.0 0.0 9.4 11.5 8.8 12.1 2.6 2.0 0.0 9.4 0.2 0.0 0.0 1.6 2.4 0.0 4.5 0.0 12.5 7.0 0.2 3.7 10.9 0.2 10.6 0.8 1.4 5.4 11.0 12.7 18.2 28.8 0.0 0.0 0.0 8.0 0.0 7.7 0.3 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.8 0.1 0.0 0.3 0.1 0.0 9.2 19.4 2.9 11.6 11.3 5.1 30.1 5.5 15.6 25.2 CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573784-46598408 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 17.8;HHSteC: 13.2;NTERA-2: 15.8;PC-3: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 15.4" "Group enriched" "Detected in many" 10 "granulocytes: 9.4;monocytes: 8.0;T-cells: 15.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favourable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" 13.1 7.5 4.9 3.8 6.6 4.7 12.1 4.7 10.3 10.5 4.4 3.6 2.5 2.2 5.0 4.1 4.2 3.2 10.7 25.6 4.1 4.0 3.6 11.0 5.4 3.7 4.5 4.7 27.0 3.4 2.4 3.4 5.9 3.6 3.9 2.2 1.4 2.7 3.7 4.3 5.4 3.3 3.5 1.9 17.1 3.4 3.6 1.8 2.4 4.2 1.4 2.0 4.1 8.7 1.0 1.0 9.4 8.0 0.4 15.4 1.6 4.1 3.4 2.9 2.7 8.5 6.0 0.1 5.7 4.1 1.5 2.0 0.9 1.6 0.0 17.8 2.3 3.1 2.8 1.0 1.3 2.4 6.2 0.8 0.3 3.0 13.2 1.4 0.1 2.0 0.8 2.9 2.4 4.7 0.0 3.6 1.1 1.9 0.5 1.8 15.8 13.2 2.7 2.5 7.4 4.2 0.1 6.8 2.6 0.8 0.2 0.6 1.0 0.3 1.1 4.8 0.5 2.5 2.6 8.5 1.7 1.2 5.3 0.0 0.3 1.2 1.9 0.6 1.4 5.9 1.3 1.0 5.3 2.5 1.0 0.6 1.1 1.0 9.4 0.4 8.0 0.6 15.4 1.6 4.9 6.6 4.7 10.3 4.1 4.0 4.5 4.7 3.6 1.8 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175723-101251932 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 72.5" "Cell line enhanced" "Detected in all" "Karpas-707: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048902 Uncertain "Secreted - unknown location" "HPA048902: " "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 23.2 15.6 14.4 14.6 13.7 15.7 17.7 8.5 11.1 17.7 6.5 9.6 8.6 4.9 15.6 11.6 9.1 14.1 19.0 19.0 11.4 7.5 9.0 8.1 20.6 12.4 15.3 5.5 21.9 6.0 5.9 8.7 72.5 12.9 13.6 7.0 12.1 9.8 10.1 7.3 13.7 6.8 16.4 11.9 18.4 9.3 10.8 13.5 8.3 9.7 9.2 8.7 14.3 20.0 1.9 1.5 8.7 2.4 1.2 3.2 1.0 2.7 3.4 11.7 5.9 6.1 8.2 7.8 6.8 6.0 8.2 8.4 2.9 2.2 6.7 4.0 11.2 7.7 7.7 8.6 9.1 7.4 3.9 13.3 3.9 3.5 7.6 20.1 13.7 7.5 7.3 7.1 6.5 9.7 4.8 68.3 6.2 2.4 2.7 13.8 13.4 2.5 6.2 11.7 9.9 5.7 5.5 2.0 11.0 7.1 3.5 12.3 4.0 24.9 8.1 13.5 7.7 6.3 14.2 12.1 28.0 3.9 10.4 19.1 10.0 0.0 2.4 5.1 2.9 1.5 3.1 1.7 1.8 3.1 1.5 1.9 1.0 1.9 8.7 1.2 1.6 0.9 3.2 1.0 14.4 13.7 8.5 11.1 11.4 7.5 15.3 5.5 12.9 13.5 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904472-130186634 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 12.5;ASC TERT1: 11.1;HSkMC: 7.2;TIME: 6.7;U-138 MG: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 11.7 1.6 7.0 2.7 8.9 0.3 5.7 0.4 10.4 12.5 1.7 2.1 0.0 1.5 4.2 1.6 1.8 2.6 7.2 3.0 4.8 2.2 1.0 4.8 4.6 1.4 2.1 8.9 1.1 1.1 2.1 0.9 5.6 1.0 1.4 1.6 6.3 1.3 1.8 2.2 2.8 1.3 5.2 1.5 1.9 1.5 1.9 2.1 0.0 2.9 1.3 1.3 3.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.0 12.5 11.1 1.0 2.7 0.1 0.4 0.4 0.0 0.1 0.0 0.2 4.1 0.0 0.0 0.1 0.0 0.0 1.5 1.7 5.5 0.4 1.2 0.0 0.0 7.2 0.0 0.1 1.1 2.9 0.0 1.8 4.8 0.0 0.0 0.0 0.6 1.1 0.4 5.3 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.2 0.2 0.4 6.7 13.4 2.8 0.1 1.8 0.0 0.0 0.0 0.3 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.0 8.9 0.4 10.4 4.8 2.2 2.1 8.9 1.0 2.1 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Conserved helix-loop-helix ubiquitous kinase" O15111 10 100188298-100229619 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favourable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 16.6 16.6 14.0 14.3 18.9 21.3 14.2 16.0 15.8 11.8 15.0 13.0 13.9 16.1 14.7 12.4 13.5 12.0 11.7 14.5 13.3 17.6 27.2 35.8 14.0 20.8 17.9 6.9 11.4 14.5 19.6 18.2 14.2 16.4 12.9 17.6 9.5 13.9 12.5 23.6 11.0 20.6 16.1 18.6 18.7 15.1 12.5 15.6 22.5 14.5 11.7 15.5 13.8 13.6 3.7 3.4 7.2 4.8 4.0 4.3 1.4 15.6 13.2 13.6 20.2 13.1 11.8 10.5 19.9 19.6 18.6 22.8 14.8 9.3 21.2 11.8 13.5 15.5 22.6 10.6 21.0 22.5 19.5 14.1 10.5 16.3 11.2 26.0 20.7 9.4 11.3 21.5 21.0 13.2 15.9 17.6 20.3 9.5 20.5 16.1 8.8 9.7 13.4 15.1 9.7 11.8 10.1 8.1 12.1 10.8 8.4 17.3 16.7 15.9 13.9 11.7 13.2 12.7 22.6 20.8 18.7 20.7 12.8 21.2 9.2 2.6 3.0 5.1 2.4 4.8 4.0 3.7 3.0 4.3 3.4 2.1 3.3 4.2 7.2 4.0 3.2 2.1 2.8 1.4 14.0 18.9 16.0 15.8 13.3 17.6 17.9 6.9 16.4 15.6 CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Cell line enhanced" "Detected in some" "HDLM-2: 22.8;REH: 40.0;U-698: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" 8.0 5.9 4.6 47.7 7.1 4.3 6.8 1.5 5.5 6.3 3.7 10.6 4.2 10.4 8.1 10.4 4.8 5.2 8.1 4.9 4.7 3.5 8.8 2.9 15.0 27.0 9.4 1.1 2.5 3.5 1.9 4.0 1.2 6.6 5.5 4.3 5.5 13.3 4.3 2.9 4.4 17.4 3.7 15.6 25.9 6.2 1.5 7.4 12.6 6.1 5.2 67.2 6.3 6.8 27.3 19.0 6.5 11.9 0.7 0.5 1.7 0.1 0.2 0.3 0.3 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.3 5.5 5.0 0.8 0.0 0.9 0.0 0.0 0.1 22.8 0.2 2.9 1.0 0.6 0.0 0.4 0.4 1.0 0.0 0.1 0.0 0.0 0.3 2.0 0.1 0.3 0.2 0.4 0.1 0.1 40.0 0.3 3.5 0.0 1.6 0.9 0.1 0.9 0.3 0.9 0.5 1.6 0.3 2.1 0.3 0.6 0.2 8.4 0.6 11.8 7.5 0.5 6.8 0.2 11.9 6.5 0.3 9.5 0.1 17.9 0.1 0.5 17.7 27.3 0.1 0.2 2.8 0.7 10.0 19.0 0.4 1.7 4.6 7.1 1.5 5.5 4.7 3.5 9.4 1.1 6.6 7.4 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685790-119877291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;brain: 35.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol Cytosol "HPA019082: AB_1846803, HPA048812: , HPA075506: " "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 1.4 4.4 14.7 3.3 14.0 15.3 1.6 12.7 35.0 1.6 4.6 2.9 0.0 4.0 1.3 1.5 3.2 0.9 1.6 1.0 9.8 5.7 5.7 1.4 3.0 3.4 3.2 21.9 0.7 0.7 1.2 2.9 2.6 7.4 1.0 5.3 0.6 1.3 1.0 1.3 5.1 3.5 2.6 5.0 5.6 3.5 8.3 9.5 5.9 1.5 0.1 4.9 1.7 1.7 0.4 0.0 0.0 0.1 0.0 1.2 0.8 15.0 13.5 11.9 11.2 1.1 3.3 7.0 11.5 9.6 12.1 9.1 8.6 6.2 10.8 6.2 8.9 9.4 8.1 6.7 16.7 7.7 5.9 13.7 8.7 5.3 0.1 7.2 12.6 0.7 0.7 14.4 8.9 9.2 8.7 9.2 11.3 7.5 13.0 11.0 6.4 9.1 11.9 21.6 3.6 2.4 6.6 8.5 4.7 19.1 3.7 9.1 13.5 5.2 7.0 15.1 13.9 10.3 12.5 6.3 7.0 7.4 10.0 7.9 23.3 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 14.7 14.0 12.7 35.0 9.8 5.7 3.2 21.9 7.4 9.5 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519659-103523111 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 158.5" "Cell line enhanced" "Detected in many" "CACO-2: 53.1;HEK 293: 135.1;SCLC-21H: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 10 "non-classical monocyte: 50.0" "Lineage enriched" "Detected in many" 17 "monocytes: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol 50000000 Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favourable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 32.4 27.3 75.4 10.4 114.6 3.1 5.3 94.3 158.5 29.1 121.5 51.4 23.8 17.6 37.3 8.9 28.6 35.7 17.8 36.4 60.7 43.2 26.7 3.4 12.8 3.6 63.4 93.3 15.8 10.2 20.3 9.7 3.7 63.3 107.5 55.0 43.9 18.3 92.1 19.1 14.4 17.5 53.2 31.9 3.6 66.7 22.1 50.9 0.0 19.8 7.8 3.9 43.0 13.0 0.0 2.9 1.4 50.0 0.0 0.1 0.9 0.3 6.7 26.9 1.4 0.2 0.2 0.5 2.9 0.0 0.3 0.1 53.1 0.8 0.0 3.2 2.0 5.9 7.8 0.1 0.0 1.2 135.1 10.0 29.7 18.2 1.1 0.0 8.2 1.0 0.0 0.2 0.1 0.0 17.4 0.4 0.4 2.2 0.2 0.3 10.5 21.0 1.7 0.5 27.6 4.9 0.2 76.9 31.6 5.7 0.9 2.1 2.5 4.1 0.1 0.1 5.2 0.5 12.6 1.3 0.3 0.9 0.7 0.2 0.9 0.3 0.1 1.4 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 50.0 0.0 0.1 0.9 75.4 114.6 94.3 152.7 60.7 43.2 63.4 93.3 63.3 50.9 CKM CKMM ENSG00000104879 "Creatine kinase, M-type" P06732 19 45306414-45322977 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 1374.7;tongue: 354.9" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 36.8" "Group enriched" "Detected in many" 33 "head and neck cancer: 64.4;prostate cancer: 14.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 2.8;intermediate monocyte: 1.1;myeloid DC: 2.1" "Group enriched" "Detected in many" 25 "dendritic cells: 2.1;monocytes: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047859 Enhanced 190000000 "HPA047859: " "unprognostic (3.51e-1)" "unprognostic (7.63e-2)" "unprognostic (2.61e-2)" "unprognostic (4.14e-1)" "unprognostic (7.68e-3)" "unprognostic (4.04e-3)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (5.19e-2)" "unprognostic (1.81e-1)" "unprognostic (5.00e-1)" "unprognostic (9.46e-3)" "unprognostic (9.67e-8)" "unprognostic (3.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" 13.9 0.1 0.2 0.1 0.2 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 23.5 21.1 0.1 0.1 187.9 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 2.8 0.1 0.8 17.6 0.2 1374.7 0.2 0.2 0.2 0.3 0.1 0.5 0.3 0.0 0.0 11.1 354.9 24.8 0.2 0.1 0.0 2.1 0.0 2.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.9 0.0 0.1 8.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2;esophagus: 19.9;intestine: 25.5" "Cell line enhanced" "Detected in many" "HaCaT: 42.6;hTCEpi: 19.3;SCLC-21H: 15.1;SK-BR-3: 33.5;T-47d: 29.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043491 Uncertain "Intracellular and membrane" 2100000 "HPA043491: " "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" 0.0 0.7 4.8 1.9 6.3 0.0 2.1 17.2 12.6 1.8 25.5 24.7 0.0 0.0 19.9 0.4 3.0 0.0 5.6 7.9 0.9 0.0 0.0 0.0 5.0 0.0 0.1 2.1 1.4 2.5 0.5 24.1 7.2 0.0 0.0 13.0 21.7 0.9 1.1 0.0 7.8 0.0 0.6 4.4 1.4 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.3 0.0 10.6 0.0 0.0 0.0 0.0 2.2 7.3 0.0 0.4 0.0 42.6 6.1 12.5 0.0 0.0 4.7 0.0 0.7 0.2 0.0 0.0 2.0 0.0 19.3 0.0 3.3 0.0 1.9 0.0 0.0 9.9 0.0 0.0 3.0 2.3 0.0 0.0 1.9 2.0 1.5 15.1 5.9 0.0 33.5 2.2 29.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.7;intestine: 28.1" "Cell line enhanced" "Detected in many" "HaCaT: 40.4;HBEC3-KT: 15.5;hTCEpi: 20.8;SCLC-21H: 15.6;SK-BR-3: 49.7;T-47d: 28.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043491 Uncertain "Intracellular and membrane" 2100000 "HPA043491: " "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavourable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" 0.0 0.3 5.4 1.6 8.8 0.0 1.6 52.7 13.6 0.7 28.1 22.4 0.0 0.0 13.8 0.2 2.8 0.0 6.8 7.4 0.9 0.0 0.0 0.0 5.4 0.0 0.2 1.4 1.3 3.7 0.6 23.1 4.8 0.0 0.0 7.6 16.2 1.2 1.8 0.0 10.0 0.0 1.7 4.1 1.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 2.3 6.9 0.0 0.3 0.0 40.4 8.1 15.5 0.0 0.1 4.7 0.0 1.0 1.0 0.0 0.0 2.3 0.0 20.8 0.0 1.8 0.0 2.6 0.0 0.0 9.8 0.0 0.0 3.2 4.3 0.0 0.0 0.2 0.7 1.0 15.6 5.5 0.2 49.7 2.9 28.9 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233285-81266397 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 153.2;skeletal muscle: 182.4;tongue: 103.6" "Cell line enhanced" "Detected in some" "ASC diff: 3.6;BEWO: 5.9;Hep G2: 5.1;HHSteC: 3.9;T-47d: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 9 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 9 "NK-cells: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051880 Enhanced 3200000 "HPA051880: " "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 2.5 5.0 1.3 0.3 1.9 0.2 0.8 0.4 1.2 1.2 0.5 1.2 2.5 0.3 1.3 11.5 3.0 1.2 1.5 153.2 1.5 0.9 2.7 0.3 0.4 0.3 2.3 1.4 1.6 1.3 1.1 0.7 0.3 4.1 2.0 0.3 2.5 9.1 2.1 182.4 0.5 0.6 1.4 2.8 0.4 2.1 0.9 1.5 0.0 3.3 103.6 2.9 1.0 0.6 0.4 0.1 0.0 0.4 3.8 0.3 0.0 0.1 0.9 0.0 0.9 3.6 0.7 5.9 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.5 3.1 0.0 0.7 5.1 3.9 0.4 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.2 0.1 0.7 0.4 0.8 0.9 0.0 0.0 0.1 0.7 0.7 0.5 0.4 0.8 9.5 0.4 0.8 0.5 0.9 0.5 0.3 0.1 0.1 0.8 0.4 0.5 0.9 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.0 0.4 0.1 0.2 0.0 3.8 0.0 0.1 0.2 0.0 1.3 1.9 0.4 1.2 1.5 0.9 2.3 1.4 4.1 1.5 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: " "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favourable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.1 6.1 10.3 3.1 11.7 12.9 8.1 8.8 12.6 9.0 12.0 11.4 5.3 2.8 6.0 5.5 8.8 13.0 4.1 18.5 12.4 11.4 8.3 15.5 14.1 7.0 8.7 14.2 5.9 18.6 11.3 19.9 5.2 10.0 36.8 12.8 5.5 10.2 26.4 6.5 14.0 10.4 12.2 14.6 6.2 5.3 10.4 8.2 7.7 2.9 12.8 2.4 6.0 8.0 10.1 6.9 9.7 9.7 21.7 9.0 6.5 6.5 7.1 6.8 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA055366: , HPA059507: " "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavourable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favourable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 6.0 5.2 18.9 5.8 9.5 5.1 16.1 5.4 6.6 4.2 4.2 5.5 4.3 13.1 7.5 3.7 8.7 9.4 7.0 4.0 9.5 7.4 10.4 5.4 7.0 8.2 12.9 10.5 4.1 6.4 6.1 12.3 7.3 14.6 9.1 6.3 10.4 8.8 7.7 12.3 7.4 9.8 11.4 14.1 10.6 13.5 9.0 12.8 2.0 6.5 5.0 9.9 15.9 4.8 2.6 6.9 4.7 4.5 17.4 14.8 11.9 5.1 9.3 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavourable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavourable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.5 14.8 15.3 24.2 21.9 26.9 19.2 14.8 20.4 11.3 13.6 15.8 35.0 14.7 14.3 28.9 19.1 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.3 28.7 24.0 23.9 12.1 14.9 12.7 15.8 19.8 22.7 12.0 10.0 16.1 9.0 13.3 17.0 16.2 10.6 12.4 12.2 13.6 13.5 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.4 19.6 16.7 11.4 33.0 16.3 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" "Actin filaments" "HPA043746: " "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.8 6.3 5.9 8.5 17.6 14.8 9.7 6.7 7.6 4.0 7.4 6.7 5.5 3.9 5.4 2.8 9.1 7.5 5.4 6.6 14.1 5.9 1.5 11.9 8.2 6.6 3.1 5.0 6.7 7.9 6.4 8.7 2.7 3.5 11.7 5.1 2.8 4.0 11.4 3.0 3.9 4.0 5.2 5.7 4.0 2.1 6.6 4.4 7.5 4.1 6.9 4.3 6.6 5.6 8.2 3.0 4.2 7.1 7.7 2.9 3.0 5.9 7.6 4.2 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55547138 "Enzymes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 9.3 9.2 7.8 5.8 11.7 1.7 8.4 16.2 14.3 12.5 9.5 5.2 9.2 7.1 10.5 8.4 13.9 8.1 6.7 10.5 7.9 7.9 12.4 9.1 8.2 9.4 7.0 9.8 11.7 8.6 18.7 21.9 8.5 8.4 9.7 8.4 5.6 8.2 9.2 16.1 9.4 12.6 13.8 8.3 9.1 9.6 18.5 5.0 4.0 14.7 5.9 5.2 8.4 17.1 2.5 3.6 0.6 3.0 2.9 4.7 1.4 13.4 5.9 5.3 8.3 8.0 8.1 2.6 13.9 11.4 9.7 9.0 3.7 10.7 3.6 7.2 16.1 11.3 6.8 10.8 16.5 4.4 2.4 2.9 6.2 4.6 7.1 4.7 3.4 4.7 10.7 13.4 13.2 9.1 6.6 7.4 14.6 7.4 2.6 2.6 3.8 6.8 1.7 6.1 2.4 7.5 7.3 5.2 4.7 10.0 12.4 6.3 4.2 2.6 12.5 13.2 14.1 4.3 18.7 6.7 4.8 2.3 11.7 4.2 10.4 0.0 3.0 0.6 2.8 3.0 4.7 1.4 3.2 2.5 3.6 2.5 1.9 2.4 0.6 2.9 2.7 2.1 3.1 1.4 7.8 11.7 16.2 14.3 7.9 7.9 7.0 9.8 8.4 5.0 CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage and polyadenylation factor I subunit 1" Q92989 11 57648992-57661868 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057770 Supported Supported Nucleoplasm Nucleoplasm "HPA057770: " "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-3)" "unprognostic (2.13e-2)" "unprognostic (4.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.82e-2)" "unprognostic (7.58e-2)" "unprognostic (8.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.75e-1)" "unprognostic (8.78e-2)" "unprognostic (3.07e-1)" 10.8 11.7 7.0 11.2 8.8 23.5 9.6 7.2 10.9 8.5 9.3 5.6 7.6 9.0 12.0 10.0 13.6 10.1 6.2 8.1 6.0 4.5 9.9 12.8 8.7 9.9 6.5 5.1 7.3 11.8 7.2 6.8 17.3 6.1 10.5 9.2 5.6 10.3 8.1 16.7 11.8 11.7 11.2 5.0 15.4 11.5 11.3 6.5 15.4 11.8 10.8 13.2 8.8 6.9 16.2 19.0 23.7 19.1 12.8 20.9 11.6 14.0 14.1 14.1 14.9 15.6 10.4 13.5 13.8 15.3 20.9 17.6 13.0 12.7 23.3 16.9 11.5 17.3 19.5 22.3 23.3 15.8 11.4 12.6 10.1 14.7 11.9 19.3 15.3 11.5 15.9 17.7 12.7 18.9 20.4 8.1 16.8 10.0 13.9 22.0 21.6 14.8 15.0 22.8 24.7 11.2 10.0 7.7 15.1 11.7 12.1 18.9 22.5 14.8 13.1 11.3 15.2 19.2 11.1 13.0 16.5 25.4 12.3 10.4 11.9 23.7 19.1 19.9 17.6 16.0 20.9 16.2 15.8 17.8 19.0 14.1 18.2 16.6 22.3 12.8 15.7 11.0 16.0 11.6 7.0 8.8 7.2 10.9 6.0 4.5 6.5 5.1 6.1 6.5 CLYBL CLB ENSG00000125246 "Citrate lyase beta like" Q8N0X4 13 99606669-99897134 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced Approved Cytosol Cytosol "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favourable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 4.2 11.6 6.2 10.4 9.4 2.6 6.0 6.7 6.4 4.6 11.2 3.8 4.8 13.6 5.2 7.6 6.4 4.7 8.3 12.3 5.1 6.3 35.0 57.7 4.7 9.6 7.9 8.6 3.5 15.0 6.1 5.7 2.2 12.5 4.2 12.3 8.9 8.7 5.5 22.2 5.7 12.5 8.6 4.5 5.5 4.8 10.7 4.3 4.6 7.0 13.3 8.2 4.9 4.4 11.0 7.5 1.2 6.7 9.2 16.7 5.5 0.2 1.3 9.8 4.4 4.6 4.3 2.1 0.4 0.9 0.8 1.5 0.2 7.2 1.7 2.8 0.5 2.2 0.8 1.6 1.1 8.6 1.4 10.9 2.6 6.7 3.2 5.8 0.8 2.3 4.9 0.1 3.8 1.2 1.5 5.7 0.9 2.4 2.6 8.1 6.3 2.0 3.4 0.4 4.0 9.7 0.6 31.7 4.8 1.9 2.2 1.9 4.7 7.6 0.1 0.4 1.1 0.8 1.5 13.3 2.6 0.3 6.8 8.6 1.3 1.2 3.3 0.3 7.5 6.7 9.0 10.9 13.3 10.6 6.7 11.0 10.3 12.1 0.5 9.2 3.2 7.5 16.7 5.5 6.2 9.4 6.7 6.4 5.1 6.3 7.9 8.6 12.5 4.3 CMAS ENSG00000111726 "Cytidine monophosphate N-acetylneuraminic acid synthetase" Q8NFW8 12 22046174-22065674 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039905 Supported Uncertain Nucleoli,Cytosol Cytosol Nucleoli "HPA039905: AB_10795237" "unprognostic (5.54e-2)" "unprognostic (4.10e-2)" "unprognostic (4.25e-1)" "unprognostic (5.39e-3)" "unprognostic (1.94e-2)" "unprognostic (3.99e-2)" "unprognostic (2.30e-2)" "unprognostic (4.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-1)" "unprognostic (7.53e-2)" "prognostic unfavourable (7.19e-4)" "unprognostic (2.27e-1)" "unprognostic (1.91e-2)" "unprognostic (3.65e-1)" "unprognostic (2.03e-1)" 8.1 28.2 28.1 9.6 31.6 17.6 14.9 16.3 39.3 12.1 34.3 14.5 17.1 29.4 12.8 32.0 33.2 10.0 11.0 18.1 28.8 33.4 12.8 31.9 7.9 9.8 33.9 27.3 11.9 18.6 14.6 14.3 20.2 34.3 17.0 33.1 10.2 14.8 12.9 18.2 12.9 32.9 13.3 18.0 8.5 12.9 30.2 14.8 6.4 10.9 11.9 12.4 11.8 17.2 12.2 19.5 19.4 18.9 22.8 19.9 15.0 19.5 15.8 19.5 9.2 15.3 19.2 28.4 13.7 15.0 14.9 15.7 35.4 22.7 17.4 13.4 11.7 16.0 11.5 19.0 20.1 22.9 14.4 52.4 12.9 17.8 14.3 13.8 27.8 12.9 18.1 18.9 28.3 19.7 32.9 8.9 26.3 25.8 15.8 32.1 47.1 22.1 11.3 20.4 16.5 17.7 21.5 7.8 13.7 10.8 19.1 15.3 26.3 18.9 14.3 16.8 13.9 14.7 25.1 6.1 7.8 23.1 27.3 10.8 16.9 10.3 17.9 19.4 13.7 18.9 17.8 12.2 18.6 18.1 19.5 12.1 16.8 17.4 1.8 22.8 16.5 12.3 19.9 15.0 28.1 31.6 16.3 39.3 28.8 33.4 33.9 27.3 34.3 14.8 CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333797-47378839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" 2100000 Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" 35.0 17.0 28.5 30.4 24.4 14.8 72.2 18.0 35.8 26.8 44.8 17.8 20.9 53.7 16.5 19.3 42.2 13.5 39.2 28.6 28.0 31.4 26.2 88.2 36.8 46.2 35.1 16.8 16.2 42.3 19.3 16.6 16.0 25.4 32.8 48.1 16.2 50.8 18.3 30.4 22.2 64.9 46.9 33.1 21.6 35.9 8.6 18.2 25.6 31.7 26.7 28.0 34.0 39.0 11.2 10.6 23.1 12.4 15.0 17.5 12.1 30.3 17.0 22.0 19.7 40.3 47.2 31.3 54.1 32.6 32.9 33.5 15.1 21.1 45.0 27.9 36.7 20.7 16.3 28.0 45.1 68.1 13.3 35.0 23.5 26.1 26.3 49.8 25.6 26.4 33.9 27.4 30.8 34.0 32.9 36.4 42.8 11.1 40.4 23.5 14.0 23.6 25.2 38.2 33.8 32.0 33.5 20.0 10.6 38.7 45.0 31.0 11.2 29.8 31.8 41.2 23.8 39.3 44.4 26.5 36.6 30.7 32.5 30.9 28.1 23.1 10.2 18.2 13.6 10.7 17.5 11.2 15.5 16.7 10.6 10.2 14.7 14.0 4.2 15.0 12.4 8.9 16.0 12.1 28.5 24.4 18.0 35.8 28.0 31.4 35.1 16.8 25.4 18.2 CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 13.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.7;HEL: 19.7;MOLT-4: 10.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041430 Approved Approved Mitochondria Mitochondria "HPA041430: AB_10796674" "unprognostic (2.37e-1)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "prognostic unfavourable (4.71e-4)" "unprognostic (1.82e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-2)" "unprognostic (8.93e-2)" "unprognostic (6.63e-2)" "unprognostic (4.54e-3)" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (7.69e-2)" "unprognostic (4.32e-2)" 8.8 3.8 3.0 6.8 8.1 14.5 4.2 0.9 5.0 2.7 4.2 4.0 1.3 5.0 2.5 6.4 1.8 2.3 3.4 3.7 3.3 3.9 4.0 3.1 17.9 13.4 3.2 5.7 1.3 3.7 2.9 3.0 4.7 3.6 2.1 2.2 4.7 20.8 4.3 3.0 1.2 6.1 3.1 3.8 7.9 7.4 9.2 0.4 8.8 3.1 1.6 2.6 2.7 1.6 1.4 1.9 7.8 6.4 0.9 0.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.2 13.9 12.7 0.0 1.4 3.1 0.8 0.0 0.2 0.0 0.0 0.0 0.3 0.2 19.7 0.0 0.0 0.0 0.6 1.4 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.0 0.1 10.8 3.6 0.3 1.0 3.4 0.0 0.0 0.0 0.4 0.3 0.5 0.2 0.0 1.7 0.0 1.3 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.0 0.0 3.6 0.8 5.5 2.8 7.8 0.7 6.4 0.4 1.4 0.5 0.4 1.9 0.2 0.5 0.5 1.8 0.9 3.2 0.1 0.6 1.2 3.0 8.1 0.9 5.0 3.3 3.9 3.2 5.7 3.6 0.4 CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029954: AB_10670558, HPA029979: AB_10671363, HPA029980: AB_10671094" "unprognostic (1.33e-1)" "unprognostic (2.12e-2)" "unprognostic (6.43e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.00e-1)" "unprognostic (3.72e-1)" "unprognostic (1.68e-2)" "unprognostic (6.43e-3)" "unprognostic (2.95e-2)" "unprognostic (9.17e-2)" "unprognostic (5.24e-3)" "unprognostic (1.50e-3)" "unprognostic (3.00e-3)" "unprognostic (3.27e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" 14.4 17.4 23.1 17.3 17.7 22.4 14.6 25.0 25.0 14.5 18.0 15.5 21.3 15.0 19.5 19.4 12.6 16.9 15.0 18.8 17.6 16.1 13.9 16.6 15.2 19.2 16.0 22.7 22.6 18.4 24.4 20.2 20.6 16.9 16.3 13.1 17.1 17.6 17.9 28.9 16.6 16.5 17.6 12.5 21.7 15.9 63.9 17.8 18.4 15.7 14.1 20.7 16.2 14.8 11.1 9.8 8.1 13.2 9.7 11.5 7.8 6.9 6.6 9.5 15.5 10.8 9.9 11.5 8.3 11.5 21.1 23.7 9.9 4.6 14.4 9.4 12.2 7.8 12.1 8.6 16.2 9.9 10.7 7.9 7.7 11.0 8.3 11.4 5.4 8.5 6.4 11.6 8.3 9.8 17.6 10.6 11.0 11.3 14.4 10.2 4.8 6.3 11.5 11.3 8.2 6.8 8.4 10.5 7.9 9.3 7.2 11.9 12.2 8.8 9.0 12.7 9.5 5.0 9.3 12.1 6.3 76.3 5.0 12.0 13.9 8.1 10.2 6.4 10.1 13.2 8.5 11.1 8.9 10.7 9.8 8.1 9.9 8.0 6.6 9.7 9.9 8.2 11.5 7.8 23.1 17.7 25.0 25.0 17.6 16.1 16.0 22.7 16.9 17.8 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" "Cell Junctions" "Nuclear speckles" "HPA041700: , HPA048265: " "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favourable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 10.4 14.9 7.1 11.7 9.0 5.4 15.9 5.3 9.1 10.6 13.4 11.5 15.6 14.1 12.5 16.4 20.4 8.8 11.0 9.0 8.5 6.9 13.5 18.2 10.7 14.7 12.4 3.4 16.2 12.2 12.7 24.3 17.4 9.0 11.9 10.5 10.6 13.6 14.1 8.4 9.9 16.1 9.4 9.5 17.5 8.9 16.0 9.3 20.9 14.3 7.6 15.4 9.6 14.2 11.2 10.3 11.0 8.0 13.1 11.2 8.6 11.3 7.9 11.4 11.3 12.9 11.2 6.4 9.3 9.1 10.5 10.1 4.7 15.8 6.1 11.2 7.3 11.2 7.0 8.3 12.9 6.3 4.7 17.0 4.6 5.9 16.1 10.0 23.3 8.1 15.9 7.7 10.4 11.9 7.3 4.6 17.4 10.1 12.1 16.9 7.1 4.7 16.4 7.3 13.2 12.9 7.7 7.5 8.5 10.5 9.2 10.2 13.7 7.3 11.4 11.9 11.0 12.1 7.2 8.6 8.9 10.9 8.9 10.2 10.2 11.0 7.2 7.1 9.8 8.0 11.2 11.2 9.2 10.3 10.3 10.2 10.5 10.3 0.4 13.1 5.2 3.6 8.0 8.6 7.1 9.0 5.3 9.1 8.5 6.9 12.4 3.4 9.0 9.3 CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510127 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved "HPA005737: AB_1078544" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.64e-2)" "prognostic unfavourable (1.19e-4)" "unprognostic (2.82e-2)" "unprognostic (4.18e-2)" "prognostic favourable (1.61e-4)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "prognostic favourable (7.67e-6)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.33e-2)" 19.4 14.3 19.8 12.0 23.3 11.1 13.8 31.6 24.6 18.7 15.0 21.9 7.0 11.3 21.1 15.2 15.8 16.7 13.8 18.7 19.2 18.0 16.0 16.0 13.6 14.4 18.5 15.1 24.7 14.1 22.6 28.6 16.1 21.1 15.3 13.4 16.4 16.8 15.6 35.0 15.6 12.3 17.1 22.6 13.7 12.3 25.8 18.5 18.5 21.1 12.3 18.1 16.2 15.7 12.0 10.0 21.5 12.7 16.7 15.5 9.1 13.5 12.9 13.2 17.6 22.0 17.5 9.6 15.3 16.7 13.1 16.3 11.1 14.0 13.6 13.3 13.9 13.0 16.7 11.6 18.8 15.3 12.8 11.2 11.1 9.8 12.3 12.5 13.4 13.4 14.8 16.7 10.5 13.4 19.5 10.9 19.1 17.0 17.2 20.5 17.3 10.9 11.2 13.0 14.7 15.4 12.6 14.0 16.5 17.8 20.1 11.1 12.4 14.3 18.0 15.9 9.5 14.7 16.5 16.8 15.7 19.4 16.0 14.8 21.1 21.5 11.5 14.9 14.1 11.5 15.5 11.0 12.0 11.7 10.0 12.0 13.1 12.1 10.7 16.7 12.7 8.0 10.1 9.1 19.8 23.3 31.6 24.6 19.2 18.0 18.5 15.1 21.1 18.5 COASY "CoASY, DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" 10000 "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favourable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavourable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" 15.4 28.3 14.6 15.5 16.9 18.1 20.6 19.4 25.9 16.9 22.8 16.7 31.9 30.2 17.7 17.0 32.7 21.4 20.4 12.7 14.6 10.2 40.6 66.0 20.7 15.6 14.1 15.1 18.7 33.9 27.2 19.3 18.0 20.5 20.9 18.5 14.5 43.2 36.6 21.2 25.1 32.1 12.3 14.4 27.1 24.7 25.7 14.6 21.5 30.2 22.7 20.9 16.3 18.2 14.6 28.5 21.2 26.2 16.3 18.8 18.0 28.4 46.3 8.6 17.3 19.1 11.1 28.2 12.0 17.2 21.3 15.2 26.5 28.0 16.3 21.4 15.5 45.0 22.7 26.0 14.3 14.8 39.5 16.4 29.6 42.0 22.9 17.1 23.1 17.1 31.3 21.0 22.3 20.1 30.3 22.0 15.1 17.5 21.6 26.0 11.7 23.7 12.2 29.7 26.7 28.8 20.4 20.7 15.7 11.7 11.9 22.7 49.4 21.7 12.6 21.8 20.2 16.9 12.9 26.6 37.0 9.3 25.3 17.0 15.0 15.3 24.5 21.2 18.2 26.2 18.8 14.5 14.5 17.2 28.5 14.6 14.1 14.5 16.7 16.3 17.8 19.4 15.3 18.0 14.6 16.9 19.4 25.9 14.6 10.2 14.1 15.1 20.5 14.6 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555594-17583162 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA047821: " "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavourable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavourable (3.83e-4)" 29.8 11.4 12.1 26.9 16.5 21.3 36.2 15.6 13.1 18.2 18.5 10.8 9.6 12.0 21.9 20.2 17.6 19.2 18.1 21.7 10.8 7.1 11.1 17.8 25.1 46.1 19.4 7.3 19.0 15.2 7.9 8.1 29.6 11.8 12.6 11.6 9.5 12.0 13.0 10.7 16.7 17.3 25.7 11.3 30.9 13.9 11.2 17.9 10.3 11.3 12.7 11.9 19.6 19.1 2.5 11.5 7.6 17.4 1.4 3.6 7.1 23.0 27.3 13.3 18.3 52.7 32.8 21.2 21.6 12.7 28.5 29.7 20.6 36.4 11.8 38.8 37.9 20.6 13.5 25.1 17.4 6.7 21.7 11.3 35.5 19.5 28.9 27.0 34.6 27.1 22.5 32.0 13.4 32.0 23.1 6.0 10.3 10.2 13.6 17.5 9.8 26.6 14.5 17.0 18.0 6.0 15.3 9.6 7.0 23.2 18.5 21.9 9.6 39.4 22.3 56.8 16.1 50.3 35.1 10.7 27.1 13.0 33.5 51.5 25.7 1.1 15.0 7.6 3.4 17.4 2.0 2.3 3.2 3.2 11.5 2.5 2.3 3.6 2.4 1.4 12.6 4.4 1.9 7.1 12.1 16.5 15.6 13.1 10.8 7.1 19.4 7.3 11.8 17.9 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell line enhanced" "Detected in many" "Hep G2: 12.7;SK-MEL-30: 13.7;U-251 MG: 13.1;WM-115: 17.0" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "basophil: 8.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 2.1 9.4 10.8 1.7 16.6 1.9 2.8 10.6 39.0 2.0 3.0 31.3 0.0 1.4 3.0 5.2 1.7 3.5 3.7 11.7 15.3 7.9 1.8 1.0 4.5 1.1 20.2 12.9 2.3 3.5 1.0 1.9 0.8 17.4 8.1 2.0 3.5 4.4 3.7 11.0 1.1 1.4 3.0 21.8 1.3 3.4 5.0 22.5 0.0 5.1 1.8 1.5 2.4 1.4 0.0 0.0 8.1 0.0 0.7 0.6 0.1 0.1 0.0 4.4 0.2 2.3 3.4 0.1 1.2 0.5 0.6 0.7 2.1 0.2 0.0 0.3 3.3 0.0 4.2 0.0 1.1 4.6 2.3 0.3 0.0 12.7 0.1 4.1 0.0 2.0 0.0 0.6 0.1 0.0 4.1 5.4 4.6 0.1 0.2 0.2 3.0 0.0 0.4 0.0 0.0 0.0 0.9 1.7 2.7 0.2 0.0 13.7 0.0 0.2 0.0 0.5 0.4 0.0 13.1 8.0 0.0 0.0 0.4 2.0 17.0 8.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 10.8 16.6 10.6 17.2 15.3 7.9 20.2 12.9 17.4 22.5 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941607-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.3" "Cell line enhanced" "Detected in many" "MCF7: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Supported "Endoplasmic reticulum,Vesicles" 560000 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favourable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favourable (5.67e-4)" "prognostic unfavourable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 18.6 49.0 29.4 14.3 28.8 24.3 27.8 19.6 32.9 22.4 23.4 42.4 36.1 21.0 19.8 33.8 58.1 19.4 36.8 28.1 28.9 22.3 31.1 139.3 30.9 17.0 29.0 18.4 36.3 27.2 14.1 12.7 59.0 23.3 25.7 8.9 24.9 67.3 30.9 21.5 27.7 28.6 15.5 41.0 17.8 24.8 18.2 23.7 11.5 19.2 44.0 32.0 36.3 28.0 11.2 55.1 10.9 60.0 12.9 15.6 28.0 19.0 19.6 2.2 19.4 22.1 19.7 0.8 21.6 27.3 18.5 21.3 16.6 22.2 7.7 9.6 30.9 26.1 3.7 23.2 4.9 16.6 24.7 13.7 10.5 38.7 41.3 22.8 5.5 25.0 28.7 16.1 16.0 17.4 55.4 16.4 15.0 118.0 8.9 41.0 4.8 6.6 13.5 19.4 10.6 19.6 60.5 9.5 8.3 7.2 61.3 17.8 13.2 64.3 20.8 33.2 12.7 10.9 16.2 6.0 2.5 6.3 35.8 30.9 22.8 10.2 60.0 10.9 15.6 39.9 12.8 11.2 10.8 12.6 47.7 10.7 9.6 10.6 2.4 12.9 26.6 55.1 13.3 28.0 29.4 28.8 19.6 32.9 28.9 22.3 29.0 18.4 23.3 23.7 COP1 "FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1, E3 ubiquitin ligase" Q8NHY2 1 175944831-176207493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavourable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 22.4 15.8 14.8 20.1 16.7 19.1 19.3 24.6 19.7 21.4 23.9 15.3 17.7 16.1 23.5 16.5 22.3 14.9 15.5 14.5 12.8 11.6 17.2 22.9 17.8 24.1 13.1 11.3 14.4 20.8 15.6 24.5 17.2 15.7 15.4 26.1 18.1 20.2 21.4 19.2 25.4 22.1 19.7 10.9 27.1 17.5 23.4 15.0 39.3 18.3 15.8 25.0 22.6 17.6 1.5 2.0 13.7 3.4 0.5 2.7 1.0 14.1 7.6 12.4 6.7 12.5 12.8 23.5 11.0 13.5 11.8 11.2 12.9 15.0 29.0 10.8 12.5 13.4 11.4 16.7 10.6 9.0 7.0 12.3 9.4 12.7 13.2 22.1 14.3 11.3 14.0 11.5 14.7 16.7 17.9 11.4 14.0 17.7 13.0 11.7 21.3 0.8 11.3 10.8 16.9 16.2 43.8 10.0 17.6 12.9 20.6 14.0 14.6 29.6 16.0 10.0 7.0 13.4 9.4 14.7 25.1 26.4 8.4 13.1 11.5 6.1 2.7 10.1 1.8 3.4 1.4 1.4 2.1 1.4 2.0 1.5 2.7 2.0 13.7 0.5 3.1 1.1 1.5 1.0 14.8 16.7 24.6 19.7 12.8 11.6 13.1 11.3 15.7 15.0 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease mutation, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.6 25.5 4.9 8.4 7.0 8.9 9.9 1.9 6.0 7.4 12.1 5.8 8.4 7.8 8.0 10.2 13.1 5.4 7.4 17.5 4.3 4.1 8.0 14.9 9.8 9.0 6.5 3.4 8.0 5.9 6.7 12.3 7.2 5.0 6.6 12.5 5.2 12.7 8.5 21.8 13.8 8.2 5.8 6.7 14.1 4.8 6.6 6.7 2.9 10.1 23.9 9.2 6.2 7.4 3.6 11.8 6.0 17.4 3.7 2.0 6.8 11.6 6.8 6.8 12.8 5.3 5.4 4.8 7.6 12.5 14.4 16.8 4.7 16.8 7.9 5.5 13.4 9.0 11.4 12.3 18.1 8.0 7.2 7.0 8.9 6.7 5.7 14.2 33.9 8.0 7.8 6.9 12.0 14.3 4.5 9.4 13.3 12.0 3.7 9.6 5.0 9.7 6.5 5.3 10.2 20.9 5.6 4.7 3.1 8.7 11.0 3.8 7.1 7.8 9.9 6.7 7.0 5.1 10.5 2.8 2.2 4.6 13.2 16.8 9.2 1.1 16.3 2.3 1.6 14.4 1.2 3.6 1.8 1.5 11.8 3.5 1.3 2.0 6.0 3.7 17.4 6.2 2.0 6.8 4.9 7.0 1.9 6.0 4.3 4.1 6.5 3.4 5.0 6.7 COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369400-99394204 "Enzymes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA031273: AB_10611107, HPA031274: AB_10602176" "unprognostic (1.81e-2)" "unprognostic (2.69e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" "unprognostic (2.41e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.40e-1)" "unprognostic (8.77e-2)" "unprognostic (9.78e-2)" "unprognostic (1.09e-1)" "prognostic favourable (6.86e-5)" "unprognostic (4.61e-2)" "unprognostic (1.81e-1)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" 5.2 7.8 8.6 4.2 10.8 3.2 7.5 13.6 16.3 4.5 8.9 4.5 4.3 6.9 4.3 6.8 8.2 4.5 3.0 21.7 8.2 7.5 10.2 12.4 2.9 7.1 6.9 12.0 6.0 5.7 11.6 7.4 2.5 9.8 6.8 11.0 7.3 11.7 7.6 28.0 5.8 6.3 6.6 4.6 4.8 5.2 2.3 6.0 4.1 4.3 16.8 7.0 7.5 4.6 6.6 8.0 9.4 7.4 9.7 12.5 5.3 11.9 6.9 8.4 11.8 5.4 6.1 11.5 10.4 6.4 15.7 18.2 9.6 5.2 11.8 6.9 7.7 11.2 13.9 16.2 19.2 12.4 17.8 14.3 9.4 10.2 7.2 20.6 5.6 3.9 9.9 9.2 9.4 9.5 21.7 8.9 8.3 11.9 9.0 17.3 10.1 13.3 4.4 8.6 15.6 12.3 10.5 13.1 7.0 7.2 11.1 13.5 13.6 13.7 3.4 6.9 10.1 10.5 15.7 3.1 5.8 18.4 8.8 20.1 10.1 9.4 3.3 2.4 6.0 7.4 6.8 6.6 7.6 9.5 8.0 3.1 12.5 9.5 0.5 9.7 6.3 5.2 5.5 5.3 8.6 10.8 13.6 16.3 8.2 7.5 6.9 12.0 9.8 6.0 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503274-120534434 "Enzymes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria Nucleoli Mitochondria "HPA049487: " "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 14.6 21.7 15.8 16.1 16.7 7.0 29.5 15.6 21.3 12.5 16.4 13.5 21.8 15.7 12.6 16.4 14.0 15.5 13.5 31.9 14.8 13.1 26.0 39.8 17.6 19.1 17.5 15.4 15.1 28.6 14.2 13.4 18.6 19.4 12.7 17.1 11.6 17.9 17.8 58.4 11.1 13.2 14.0 18.5 14.6 12.4 16.9 15.0 17.2 17.7 30.4 15.2 10.1 17.0 21.3 27.4 9.7 19.6 25.1 28.2 22.4 16.3 26.2 23.7 6.8 31.2 24.1 16.3 20.0 13.1 20.5 13.0 10.5 13.8 16.5 23.7 20.9 17.7 21.0 22.2 21.1 20.6 12.4 22.0 16.1 17.3 25.6 23.9 13.8 23.0 24.1 19.1 22.5 18.0 21.5 12.1 23.6 21.5 13.8 27.5 20.8 20.4 25.6 24.0 23.9 26.4 12.5 17.9 14.4 14.5 7.4 27.2 37.2 19.7 17.9 14.2 16.3 10.5 13.2 26.2 22.0 18.8 16.2 22.7 17.0 9.4 19.6 9.7 18.8 19.2 18.2 21.1 20.4 19.9 27.4 21.3 28.2 22.3 2.1 25.1 17.9 18.0 24.4 22.4 15.8 16.7 15.6 21.3 14.8 13.1 17.5 15.4 19.4 15.0 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria 790000 Mitochondria "HPA008835: AB_1078563" "prognostic unfavourable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favourable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 18.0 18.3 9.9 9.9 12.1 15.8 24.4 7.0 10.3 12.8 31.9 8.2 14.1 33.7 17.0 7.2 11.2 12.8 14.7 14.6 12.0 6.6 30.6 62.0 13.1 10.1 10.5 8.6 17.0 24.4 16.9 13.8 8.7 10.8 15.6 22.0 19.7 12.9 11.4 6.9 10.3 33.4 16.9 8.7 18.9 16.8 10.4 9.0 17.9 13.2 7.5 7.6 11.3 30.2 2.5 11.9 10.6 8.6 5.7 8.8 2.5 8.3 14.8 2.1 14.5 9.5 8.6 0.6 6.7 5.5 5.3 1.1 0.5 28.3 0.0 24.8 17.6 27.5 18.8 4.0 1.6 13.4 1.8 20.5 16.2 6.8 14.2 11.9 24.9 8.9 1.9 10.6 6.4 18.8 2.1 16.9 4.8 24.0 9.7 21.1 0.2 15.8 27.1 0.3 36.5 12.5 20.9 0.3 9.5 18.5 35.7 5.9 31.9 11.6 18.8 11.6 0.2 23.2 9.6 13.2 16.8 8.5 12.2 8.8 12.6 9.2 7.8 10.6 8.8 8.6 5.1 2.3 5.5 5.3 5.0 2.5 3.4 7.0 3.8 5.7 7.2 11.9 2.9 2.5 9.9 12.1 7.0 10.3 12.0 6.6 10.5 8.6 10.8 9.0 CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 162.2;skeletal muscle: 59.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA029583 Approved "HPA029583: AB_10600864" "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (6.71e-3)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (8.89e-2)" "unprognostic (7.16e-2)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-3)" "unprognostic (9.76e-3)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" "unprognostic (1.14e-1)" "unprognostic (8.43e-2)" "unprognostic (3.15e-5)" 4.3 1.5 1.7 2.9 2.7 3.3 2.8 9.1 2.0 1.7 3.1 1.8 1.6 3.8 1.6 2.9 3.7 0.9 1.6 162.2 2.1 1.9 4.0 4.2 1.9 3.5 2.5 1.6 1.6 3.1 17.2 4.5 2.3 2.2 2.5 2.9 5.2 4.3 1.6 59.8 3.8 3.7 1.6 2.2 5.0 3.8 19.7 2.3 1.9 5.2 39.6 4.5 2.0 1.6 0.5 2.3 0.7 0.4 2.3 1.6 0.3 5.2 4.8 15.5 5.7 3.5 2.1 12.2 0.6 2.0 2.6 3.0 2.3 4.6 10.4 1.7 1.2 8.7 8.2 1.8 2.3 4.2 9.1 5.2 14.1 2.4 0.9 5.4 15.2 1.2 14.1 1.9 3.1 0.4 1.8 17.6 2.5 7.4 2.1 10.6 3.4 3.2 9.6 5.1 2.3 6.6 12.4 4.3 8.4 3.9 6.3 6.5 6.9 11.4 1.1 7.6 8.1 5.0 1.8 15.0 3.4 5.4 3.5 9.7 5.1 0.0 0.4 0.5 1.0 0.1 0.0 0.5 1.6 0.3 2.3 0.2 0.4 0.2 0.7 2.3 0.2 0.3 0.1 0.3 1.7 2.7 9.1 2.0 2.1 1.9 2.5 1.6 2.2 2.3 CPT1C "CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0" "Cell line enhanced" "Detected in many" "AF22: 18.4;AN3-CA: 15.5;SH-SY5Y: 33.2;U-87 MG: 13.9" "Cancer enhanced" "Detected in many" "glioma: 9.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014529, HPA063621" Approved Approved Centrosome Centrosome "HPA014529: AB_1847206, HPA063621: " "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "prognostic favourable (1.84e-4)" "unprognostic (4.36e-1)" "unprognostic (1.92e-10)" "unprognostic (9.44e-4)" "unprognostic (3.35e-2)" "unprognostic (3.91e-1)" "unprognostic (4.72e-3)" 3.4 9.3 11.2 3.1 18.9 0.8 1.1 16.3 34.0 4.1 1.9 8.9 0.2 2.7 6.4 5.3 1.8 4.1 7.6 2.8 11.9 12.8 1.6 1.6 2.5 2.6 8.0 13.4 3.8 1.2 0.7 15.6 1.9 11.4 2.8 1.7 7.4 1.5 4.8 1.7 1.5 2.4 7.8 6.6 4.2 1.4 4.1 6.3 0.0 1.7 0.2 1.7 4.4 1.9 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 18.4 15.5 6.7 5.2 0.0 5.8 11.7 7.5 10.6 0.3 0.0 0.3 0.0 5.8 1.3 0.0 0.0 4.0 0.2 0.0 0.0 0.0 0.0 10.8 0.0 0.0 6.1 0.0 6.1 0.0 10.4 0.0 0.0 0.4 0.3 0.1 0.0 0.8 3.8 0.0 0.0 0.0 0.4 0.0 12.9 33.2 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.1 3.5 2.9 0.1 1.3 0.1 13.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 11.2 18.9 16.3 23.4 11.9 12.8 8.0 13.4 11.4 6.3 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196429-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria "Nucleoplasm, Nucleoli, Mitochondria" "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favourable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favourable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 7.5 15.5 5.3 6.8 6.1 2.3 6.5 4.0 7.2 5.1 15.4 9.4 10.7 16.6 5.1 7.6 10.5 5.4 11.3 21.4 4.3 4.5 19.8 69.0 6.9 8.3 5.7 3.7 5.3 15.9 10.7 11.5 18.1 6.4 6.0 15.6 13.8 11.8 12.2 13.6 6.0 18.9 5.5 5.2 10.3 10.1 11.2 4.7 9.7 8.3 7.2 10.3 8.0 4.9 5.9 12.4 10.0 13.1 4.8 8.0 6.5 7.8 3.3 7.7 7.5 6.6 3.9 8.8 4.9 5.0 7.1 6.6 1.6 6.7 13.5 7.5 2.3 7.9 14.3 11.3 6.0 7.4 8.4 7.7 4.5 1.3 9.8 7.3 7.4 8.4 9.7 5.1 4.4 4.8 9.8 4.8 4.4 4.6 5.7 6.0 14.4 8.8 6.6 7.3 14.3 8.8 7.4 11.5 7.7 9.8 12.5 18.5 14.5 15.6 4.7 4.0 3.2 7.0 4.0 14.9 9.1 8.3 5.1 8.4 5.8 4.1 8.4 10.0 5.1 12.6 6.2 4.5 4.9 5.9 12.4 5.9 8.0 5.5 5.1 4.8 13.1 6.4 7.0 6.5 5.3 6.1 4.0 7.2 4.3 4.5 5.7 3.7 6.4 4.7 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094810-129111189 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 98.6;testis: 71.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" 13000 "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_1847209" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favourable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favourable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 11.6 13.4 8.4 4.6 9.2 5.9 10.7 7.5 15.9 8.3 15.4 8.6 6.2 24.3 6.5 9.5 9.4 5.4 10.0 17.3 7.7 7.9 12.9 50.0 4.2 3.1 8.3 9.1 7.3 33.1 16.8 3.2 7.9 9.3 10.5 4.4 8.1 14.7 7.9 98.6 7.0 22.8 8.3 5.2 4.6 8.1 71.7 4.4 2.4 8.0 20.2 4.4 9.3 6.8 2.6 11.3 6.0 11.3 6.0 10.0 8.1 0.1 18.3 6.4 13.2 12.0 16.1 9.4 7.8 8.7 9.5 6.0 3.8 7.4 0.7 4.7 13.1 3.3 1.7 2.8 3.4 11.8 0.4 3.6 9.2 14.8 17.1 0.1 14.0 14.7 0.0 8.0 0.2 12.4 1.7 3.8 9.8 3.7 0.3 8.1 1.5 8.2 9.1 12.3 6.1 9.2 0.3 2.1 6.6 0.0 4.2 2.7 26.7 4.0 11.2 14.3 1.0 17.9 7.7 13.0 11.0 0.0 16.9 2.2 9.1 2.5 11.3 6.0 5.0 7.4 10.0 2.4 6.9 6.6 11.3 2.6 4.3 4.7 2.9 6.0 7.3 5.3 6.4 8.1 8.4 9.2 7.5 15.9 7.7 7.9 8.3 9.1 9.3 4.4 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880726 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: " "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favourable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 18.5 10.9 17.2 22.8 17.5 37.0 17.4 42.6 18.8 20.1 17.2 16.8 17.1 9.9 25.1 15.2 14.1 18.9 21.3 14.5 17.1 8.7 11.1 12.3 16.9 14.4 20.5 12.0 31.6 23.4 24.3 13.0 13.3 15.8 18.4 11.6 14.6 14.9 16.7 28.2 20.4 16.4 17.0 13.6 17.4 14.7 29.1 20.2 29.6 19.5 13.8 16.1 19.0 29.9 4.7 2.3 10.6 3.8 2.0 2.7 1.1 5.5 14.3 18.6 8.2 11.4 11.3 9.6 8.0 13.5 13.9 13.5 12.9 10.5 15.4 9.6 15.3 10.8 21.4 6.6 15.8 26.0 8.6 12.1 13.2 8.2 12.6 12.1 17.4 10.0 6.7 15.4 18.6 10.4 13.7 21.1 7.5 19.1 8.0 5.8 15.2 5.9 37.8 14.7 11.8 5.4 7.5 15.5 10.2 13.7 13.5 8.1 12.0 11.9 16.1 17.0 16.9 8.7 7.3 9.9 10.6 29.9 3.4 7.3 11.9 2.9 1.7 1.3 2.7 2.2 1.4 4.7 1.3 2.0 1.0 3.3 1.4 1.7 10.6 2.0 3.8 2.3 1.3 1.1 17.2 17.5 42.6 18.8 17.1 8.7 20.5 12.0 15.8 20.2 CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006090-6040053 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 84.2" "Cell line enhanced" "Detected in all" "Hep G2: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (8.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.89e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (9.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.83e-2)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "prognostic favourable (8.02e-4)" 23.0 30.4 9.1 13.2 9.2 9.9 15.0 6.8 9.9 11.5 30.4 8.2 18.5 24.0 11.6 10.8 11.7 10.5 17.2 84.2 7.9 7.5 32.9 67.4 16.4 8.3 7.9 7.7 12.6 27.0 10.2 10.1 13.3 9.5 14.4 14.8 9.1 18.3 13.4 48.5 7.2 33.1 10.5 6.8 11.0 19.3 12.3 7.1 13.1 17.2 23.7 9.6 11.7 8.6 4.9 3.7 1.1 2.4 3.6 5.2 1.1 20.0 15.2 9.7 12.5 27.1 24.7 10.4 12.7 16.4 13.1 15.7 20.0 13.9 21.9 9.2 16.4 13.1 18.7 22.9 19.7 6.2 10.9 29.9 6.1 73.2 18.4 28.4 9.9 14.5 18.3 13.7 23.4 17.6 20.8 10.0 14.6 8.0 18.8 25.4 17.1 11.9 12.4 14.2 23.3 19.6 7.9 15.7 13.4 12.8 32.4 21.6 11.0 18.2 11.3 14.4 10.1 14.5 16.9 9.8 21.5 22.6 5.7 24.1 13.2 0.0 2.4 1.1 2.6 2.0 5.2 4.9 1.7 2.2 2.6 1.9 3.6 1.9 0.1 3.6 1.0 3.7 1.5 1.1 9.1 9.2 6.8 9.9 7.9 7.5 7.9 7.7 9.5 7.1 CROT COT ENSG00000005469 "Carnitine O-octanoyltransferase" Q9UKG9 7 87345681-87399795 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 34.6;RT4: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019052, HPA019364, HPA019365" Enhanced Approved Vesicles Vesicles "HPA019052: AB_1847172, HPA019364: AB_1847173, HPA019365: AB_1847174" "unprognostic (2.80e-2)" "unprognostic (6.47e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-2)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (9.93e-3)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.84e-2)" "unprognostic (3.48e-1)" "prognostic favourable (2.55e-6)" "unprognostic (3.52e-2)" "unprognostic (1.34e-1)" "unprognostic (7.60e-3)" "prognostic favourable (4.02e-4)" 4.6 10.1 9.3 5.1 9.6 1.6 10.5 7.4 8.4 9.0 9.4 5.5 24.1 19.6 10.0 12.6 17.0 6.8 8.7 5.9 5.2 5.4 12.3 21.5 4.2 3.4 5.4 6.6 7.2 4.6 15.5 9.1 13.7 5.8 14.8 7.0 9.8 8.3 32.3 7.2 15.0 19.1 8.8 6.8 4.8 4.9 3.8 4.7 7.4 27.1 8.4 8.0 22.4 15.3 2.2 2.3 3.4 5.5 13.0 9.5 3.0 7.0 5.2 6.5 2.2 6.2 5.7 4.8 7.5 7.1 4.6 5.0 2.8 3.7 3.0 6.7 6.3 8.9 1.0 10.0 6.5 4.2 4.5 6.5 3.7 3.5 4.0 4.0 4.0 4.6 34.6 3.7 2.9 6.5 0.3 4.3 12.0 6.9 5.0 4.0 1.4 7.9 2.3 8.9 0.5 5.9 33.8 1.0 5.1 9.2 10.6 4.8 6.7 1.4 3.4 10.7 4.6 14.4 7.1 6.6 9.4 4.1 7.2 0.0 6.3 2.0 1.4 3.4 7.4 1.7 9.5 2.2 7.5 6.0 2.0 2.2 6.1 6.6 0.9 13.0 5.5 2.3 6.3 3.0 9.3 9.6 7.4 8.4 5.2 5.4 5.4 6.6 5.8 4.7 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300392 "Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 125.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria 4400000 Mitochondria "CAB075750: , CAB075751: , CAB075752: , CAB075753: , CAB075754: , HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favourable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 37.1 35.5 11.9 16.3 20.4 19.3 55.6 28.5 43.8 17.2 27.4 14.1 11.3 25.3 19.9 10.8 31.7 16.5 14.0 79.2 11.2 14.5 26.7 12.3 17.3 30.8 12.3 14.2 16.9 20.7 28.1 14.3 11.9 24.8 16.2 32.7 19.8 23.1 17.5 125.9 22.8 27.0 21.2 15.0 18.4 21.4 7.9 11.1 20.7 17.9 48.2 26.1 22.9 19.1 19.5 37.1 59.6 27.8 15.9 19.7 18.2 35.4 38.4 31.3 40.7 41.7 38.8 20.4 29.6 29.1 52.1 36.5 54.1 34.9 69.4 29.1 37.3 38.5 86.6 44.5 49.9 24.1 44.0 47.7 27.9 39.0 23.4 58.3 34.3 42.7 42.6 40.9 49.6 58.6 49.3 41.7 45.5 28.5 48.2 18.0 24.9 55.5 47.0 36.8 52.4 32.3 36.1 41.2 27.0 38.3 45.6 30.0 63.5 34.0 38.8 26.3 36.9 37.1 31.2 27.5 41.9 45.2 24.3 42.9 24.7 14.5 22.0 59.6 15.2 27.8 19.7 19.5 18.3 14.3 37.1 16.7 19.4 15.4 9.8 15.9 27.0 20.5 19.3 18.2 11.9 20.4 28.5 43.8 11.2 14.5 12.3 14.2 24.8 11.1 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 82.5;lymphoid tissue: 82.6" "Group enriched" "Detected in some" 5 "BEWO: 50.6;SK-BR-3: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 60.7;non-classical monocyte: 82.5" "Lineage enriched" "Detected in many" 4 "monocytes: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" 1500000000 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavourable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 20.9 12.4 18.2 28.1 18.9 1.8 7.7 2.8 13.5 9.3 8.3 25.4 1.1 9.2 5.9 13.1 8.4 7.9 16.1 8.7 16.4 13.7 7.8 15.1 13.7 25.4 21.3 6.0 5.3 5.2 5.9 6.4 52.1 17.1 8.5 8.4 16.8 8.0 8.7 3.0 5.8 14.5 16.2 25.8 82.6 9.0 4.9 23.0 3.1 4.2 2.9 8.2 16.4 4.7 0.0 19.1 2.9 82.5 0.0 0.1 13.9 1.7 0.0 0.0 0.0 0.8 0.2 50.6 0.1 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 19.3 0.0 0.0 7.2 0.0 0.3 0.0 0.0 1.3 0.0 0.1 0.0 2.6 0.9 0.0 0.4 18.1 0.5 0.1 60.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 2.9 0.0 82.5 1.4 0.0 13.9 18.2 18.9 2.8 13.4 16.4 13.7 21.3 6.0 17.1 23.0 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Enzymes, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 57.7" "Cell line enhanced" "Detected in some" "A549: 28.6;BJ hTERT+: 16.1;RPTEC TERT1: 20.0;U-2197: 18.3;U-87 MG: 13.2" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 20.1;granulocytes: 10.3;T-cells: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061336 Uncertain "Actin filaments" "Intracellular and membrane" "Actin filaments" "HPA061336: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 13.8 8.7 22.7 6.0 15.4 6.8 7.2 3.8 21.4 13.0 3.8 9.2 4.0 2.8 7.1 5.9 21.2 8.7 10.8 23.8 17.7 8.2 5.3 2.3 7.9 10.5 9.1 18.7 38.6 10.9 4.2 5.9 25.1 7.0 21.7 2.1 2.6 5.8 7.3 3.9 4.2 4.2 17.2 8.6 6.3 5.4 2.7 10.3 4.0 57.7 4.5 6.1 18.9 9.7 20.1 1.7 10.3 1.2 3.2 25.5 4.8 0.7 28.6 0.2 0.0 4.8 1.1 3.7 0.6 16.1 0.1 0.1 1.4 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 3.5 0.2 0.0 8.2 0.7 2.1 0.0 0.0 0.4 0.7 0.1 0.1 5.4 0.0 0.0 0.0 1.2 1.1 0.1 0.0 0.9 0.1 0.0 0.0 20.0 0.7 0.1 0.1 8.4 3.4 1.1 0.0 0.0 0.3 0.4 0.4 18.3 0.2 0.1 0.0 0.0 13.2 1.6 5.5 0.0 1.2 10.3 2.5 0.0 0.3 20.1 11.5 3.9 1.1 6.2 20.6 5.2 7.1 3.2 0.1 1.7 25.5 4.8 22.7 15.4 3.8 21.4 17.7 8.2 9.1 18.7 7.0 10.3 CSGALNACT2 "GALNACT-2, GALNACT2, MGC40204, PRO0082" ENSG00000169826 "Chondroitin sulfate N-acetylgalactosaminyltransferase 2" Q8N6G5 10 43138486-43185308 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031540 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA031540: AB_10599943" "unprognostic (1.65e-1)" "unprognostic (2.70e-2)" "unprognostic (9.10e-2)" "unprognostic (6.41e-2)" "unprognostic (1.95e-1)" "unprognostic (8.28e-3)" "unprognostic (2.85e-3)" "unprognostic (4.95e-2)" "unprognostic (2.96e-1)" "unprognostic (3.43e-3)" "unprognostic (7.65e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (3.53e-7)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "unprognostic (4.05e-3)" 18.3 8.2 9.0 16.4 13.0 80.6 11.5 10.0 10.9 11.4 12.5 17.6 4.8 6.8 14.7 7.5 9.8 12.8 18.4 11.5 10.0 9.0 8.2 11.3 24.0 25.7 11.0 6.2 16.2 6.3 7.8 15.0 18.3 11.5 10.4 8.9 19.8 7.9 8.6 12.5 8.1 9.6 15.7 14.4 21.1 8.7 6.7 9.6 24.3 9.2 6.6 12.2 17.8 11.0 2.5 11.6 15.2 16.3 8.7 6.3 5.1 4.8 3.2 6.1 5.8 9.5 16.1 1.5 17.8 24.0 7.9 12.4 1.1 5.1 8.1 4.4 16.0 4.5 5.0 6.7 12.9 9.7 3.7 4.2 3.1 3.3 20.9 9.7 8.9 16.0 7.4 17.5 36.8 10.0 1.7 24.3 16.1 2.5 7.3 5.8 2.6 4.3 4.6 6.1 3.4 6.9 2.6 5.5 10.9 4.6 4.8 11.1 6.3 8.0 14.8 6.8 10.8 21.2 11.9 6.3 8.8 4.3 14.4 23.9 3.1 10.7 9.8 15.2 6.3 11.4 5.5 2.5 4.9 4.9 11.6 2.2 5.8 4.8 9.0 8.7 16.3 3.4 5.6 5.1 9.0 13.0 10.0 10.9 10.0 9.0 11.0 6.2 11.5 9.6 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Approved Vesicles,Cytosol 1500000 "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favourable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favourable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavourable (1.74e-4)" "prognostic favourable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 9.3 8.0 9.5 39.3 11.0 19.9 12.6 18.7 13.4 12.1 13.5 11.8 7.3 16.1 13.9 6.4 33.3 10.6 11.2 14.0 9.8 8.5 8.0 20.9 15.6 67.2 11.1 7.4 10.5 6.7 6.6 10.4 8.8 12.2 9.8 8.9 9.8 13.2 7.0 8.7 14.9 26.2 8.5 10.9 62.7 13.1 8.1 10.6 62.7 8.1 9.5 47.4 17.4 13.2 35.6 22.8 49.6 46.8 16.3 30.7 19.9 12.7 18.0 8.8 14.5 8.4 6.5 7.6 8.6 8.2 16.3 11.6 16.4 11.8 57.1 11.4 7.7 13.3 18.5 17.3 4.6 27.6 22.8 48.3 6.6 16.5 11.7 25.2 61.6 9.2 8.5 11.6 10.4 12.3 13.9 19.9 9.7 21.5 18.1 14.9 10.9 12.9 20.1 7.6 41.6 7.5 28.4 14.7 10.2 11.1 23.4 14.8 16.1 37.2 10.6 19.8 10.4 15.5 14.8 10.7 21.5 58.3 10.2 48.2 13.3 20.7 19.7 49.6 23.4 42.4 20.0 29.4 20.3 23.1 22.8 35.6 15.7 18.4 39.1 16.3 46.8 13.2 30.7 19.9 9.5 11.0 18.7 13.4 9.8 8.5 11.1 7.4 12.2 10.6 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492197-149551552 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Supported Cytosol Cytosol "CAB016680: AB_1614518, HPA051334: " "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favourable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavourable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 33.5 35.8 26.0 26.9 35.2 71.0 40.2 32.0 39.3 33.8 38.2 28.2 40.5 23.2 41.0 29.4 66.1 31.8 36.0 45.7 24.4 26.1 24.0 30.1 37.5 27.3 28.0 29.8 31.7 23.9 46.9 30.9 28.7 38.0 38.1 31.4 25.5 38.5 39.3 51.4 48.4 31.8 45.8 33.9 23.6 34.2 28.6 24.1 38.6 32.0 53.1 41.1 45.0 40.0 28.6 40.6 47.4 39.6 34.2 41.9 40.8 36.1 24.1 40.7 38.5 42.0 51.5 43.5 51.6 49.1 40.2 42.4 47.0 49.0 19.3 57.1 54.8 37.0 28.7 69.5 61.6 27.9 17.3 26.1 28.0 21.6 37.8 40.8 42.0 42.1 72.1 45.2 72.8 46.3 22.0 29.1 45.3 22.6 37.5 16.5 21.4 58.8 28.0 32.2 21.9 28.0 63.0 31.4 28.2 38.3 51.4 62.8 48.2 35.6 45.9 47.4 24.9 31.4 49.1 27.0 34.5 29.7 44.2 29.7 57.2 47.4 36.6 35.4 29.0 38.7 33.1 28.6 36.7 32.9 40.6 23.4 39.9 34.0 31.1 34.2 39.6 24.2 41.9 40.8 26.0 35.2 32.0 39.3 24.4 26.1 28.0 29.8 38.0 24.1 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 10.5;testis: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 42 "granulocytes: 10.5" HPA051334 Uncertain Cytosol Cytosol "HPA051334: " "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.2 10.5 0.2 0.1 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 10.5 0.1 0.2 0.1 0.2 0.2 CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273731 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015410 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "CAB015410: AB_831049" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (7.04e-4)" "unprognostic (2.38e-2)" "unprognostic (3.43e-2)" "prognostic unfavourable (2.38e-6)" "unprognostic (8.05e-2)" "unprognostic (1.09e-1)" "unprognostic (5.00e-2)" "prognostic favourable (9.62e-5)" "unprognostic (2.23e-3)" "prognostic unfavourable (8.34e-4)" "unprognostic (3.54e-1)" "unprognostic (2.52e-1)" "unprognostic (5.52e-3)" "unprognostic (4.74e-2)" 30.1 36.3 30.8 25.9 30.8 21.0 26.3 36.3 42.8 30.9 33.0 27.7 32.9 32.6 37.9 29.8 31.3 38.0 34.9 28.5 26.2 26.9 32.0 33.5 30.1 25.8 27.2 27.8 31.4 42.8 34.2 35.9 32.8 30.3 35.3 19.3 28.4 38.0 37.7 52.3 26.7 42.3 34.1 21.4 36.4 32.5 48.3 24.6 29.2 33.0 31.8 33.7 31.4 26.1 6.4 11.4 29.6 12.1 8.7 7.6 7.1 21.3 25.4 14.5 19.9 19.1 20.4 29.1 31.4 19.8 22.5 21.1 20.8 18.4 19.5 24.8 22.3 20.7 13.6 31.8 18.2 16.5 32.9 24.2 20.2 22.3 55.5 19.9 18.5 30.9 22.6 15.3 22.8 32.8 27.2 10.4 21.2 24.9 25.5 20.8 15.5 40.0 22.0 17.9 17.3 23.7 33.5 17.9 32.3 37.5 31.3 35.1 22.4 26.1 34.5 32.4 29.1 28.1 23.8 22.7 11.0 20.9 26.0 17.1 23.5 4.7 11.0 14.6 7.6 12.1 7.4 6.4 5.9 7.3 11.4 5.6 5.0 5.3 29.6 8.7 11.1 5.5 5.2 7.1 30.8 30.8 36.3 42.8 26.2 26.9 27.2 27.8 30.3 24.6 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Low lineage specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavourable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavourable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 28.5 22.9 30.7 18.3 32.5 21.4 28.6 40.1 42.6 26.4 21.5 32.3 15.7 19.0 37.3 27.3 23.4 28.0 22.1 28.8 31.7 22.3 17.3 11.8 28.4 17.3 28.6 30.1 38.1 25.4 56.2 29.2 33.1 28.7 26.2 17.4 30.5 23.9 23.1 26.3 35.3 17.1 24.0 23.2 20.9 21.8 13.0 33.9 13.3 21.4 14.2 17.4 25.5 28.8 3.7 15.7 4.8 1.8 5.9 4.0 1.2 23.3 11.4 31.0 29.7 15.5 23.8 23.3 30.5 39.1 27.8 27.0 14.6 18.3 17.6 13.3 28.8 20.0 23.5 42.2 20.2 28.1 51.1 5.6 37.7 11.2 32.0 12.3 15.0 22.7 35.8 42.3 57.3 29.5 12.4 36.4 26.8 15.6 17.1 15.1 22.7 16.5 32.0 22.2 27.6 25.5 19.6 45.9 18.0 26.0 27.0 30.5 13.8 17.9 33.5 25.2 27.5 14.5 24.3 16.3 23.3 24.8 37.4 13.9 42.2 3.8 1.8 3.4 3.4 0.8 4.0 2.5 3.8 3.4 1.8 3.7 2.1 3.1 4.8 5.9 0.6 15.7 1.7 1.2 30.7 32.5 40.1 38.8 31.7 22.3 28.6 30.1 28.7 33.9 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165517-64356259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 7.2 7.8 10.2 11.9 15.1 11.6 8.7 12.2 10.6 8.7 7.4 7.6 11.6 7.0 11.1 9.9 15.7 10.8 7.8 5.6 8.9 7.6 8.6 6.0 8.4 9.6 6.6 4.7 8.5 8.8 10.4 16.1 7.2 7.2 6.8 7.9 10.1 8.2 14.5 6.5 10.4 6.8 11.1 5.3 8.2 6.8 41.3 7.3 11.8 11.5 5.6 11.2 8.3 10.6 4.1 4.1 8.8 5.1 5.3 8.0 2.4 5.1 10.7 7.8 10.1 6.7 9.1 7.1 6.3 6.5 10.7 9.7 8.5 10.0 8.0 3.4 9.9 11.7 20.3 12.7 12.6 15.2 5.2 7.4 8.6 5.7 7.7 13.8 8.9 8.1 16.9 10.9 15.7 11.7 9.0 8.4 9.6 7.0 7.0 4.3 7.2 5.6 11.8 9.7 6.4 8.6 20.4 12.5 7.6 8.3 5.0 7.3 8.7 5.4 12.6 9.8 11.7 7.7 7.7 9.7 18.6 6.8 9.1 10.2 6.0 0.9 3.6 5.6 5.7 5.1 8.0 3.6 5.1 4.1 2.7 4.1 5.1 4.7 8.8 5.3 4.3 4.1 3.9 2.4 10.2 15.1 12.2 10.6 8.9 7.6 6.6 4.7 7.2 7.3 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941149-1981338 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles Vesicles "HPA034868: AB_10671235, HPA056572: " "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 18.7 22.2 24.8 34.9 19.5 38.1 16.7 30.8 28.9 14.1 19.0 18.2 18.9 27.0 16.5 19.0 22.1 16.9 20.4 16.0 23.3 18.3 19.3 17.9 21.8 35.1 17.3 21.2 18.6 27.0 11.4 24.4 16.7 18.7 18.7 8.7 19.7 26.6 16.0 29.0 23.3 22.1 15.1 12.7 39.1 24.1 58.5 17.4 20.6 16.5 18.1 32.2 17.1 17.1 4.0 5.9 11.2 14.1 3.5 4.9 2.3 23.2 12.5 17.5 27.4 6.1 11.6 14.6 14.4 9.6 11.0 13.6 10.3 12.8 14.7 12.2 9.2 16.8 9.4 17.6 4.9 13.3 20.4 10.4 20.5 17.4 9.9 16.5 26.3 11.4 11.6 11.5 7.4 13.1 21.6 50.5 7.2 13.6 32.8 21.7 31.7 14.1 28.5 11.1 23.8 8.3 24.6 28.2 23.2 11.0 18.1 16.0 11.5 27.2 15.6 14.0 11.0 29.2 16.8 32.6 17.3 18.0 14.1 15.7 14.6 2.8 4.0 5.0 4.9 6.2 3.5 3.9 3.6 4.2 3.9 4.0 2.9 4.1 11.2 3.5 14.1 5.9 2.5 2.3 24.8 19.5 30.8 28.9 23.3 18.3 17.3 21.2 18.7 17.4 CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512099-123617045 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved "HPA027010: AB_10602803" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "prognostic favourable (9.90e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.92e-3)" "unprognostic (4.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.97e-3)" "unprognostic (4.38e-1)" 20.7 15.0 15.5 21.7 22.7 11.1 37.7 23.7 31.7 18.8 24.0 8.6 11.2 23.5 19.4 18.4 18.8 14.6 17.7 14.0 22.2 18.0 16.2 27.7 29.0 21.8 13.3 17.7 18.7 15.8 18.6 18.1 16.2 16.6 13.2 27.4 9.1 15.3 14.1 15.6 13.4 24.9 18.6 16.1 16.5 18.2 16.4 11.4 17.2 16.2 16.5 17.4 21.9 18.2 13.6 5.3 11.3 5.9 12.7 9.5 5.1 12.9 12.5 18.8 17.8 19.2 21.5 9.3 14.1 16.9 15.7 23.5 11.2 20.8 0.0 18.4 16.9 9.5 15.1 27.9 27.1 19.6 10.3 9.2 14.5 11.8 17.1 4.8 9.5 18.2 18.2 17.6 33.5 17.0 5.1 10.6 13.2 9.0 6.4 5.9 10.6 8.6 7.3 19.9 12.4 11.7 14.3 16.4 11.9 15.7 10.4 22.9 13.6 13.5 15.6 23.1 17.5 14.0 15.5 11.9 13.0 11.7 13.8 13.9 14.9 11.3 5.8 2.5 7.1 5.6 9.5 13.6 5.9 6.2 5.3 12.9 6.1 6.4 4.6 12.7 5.9 4.7 7.3 5.1 15.5 22.7 23.7 31.7 22.2 18.0 13.3 17.7 16.6 11.4 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: , HPA061698: " "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavourable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 21.5 26.7 23.2 20.6 31.3 16.7 24.1 26.3 32.8 22.2 26.1 28.2 19.5 21.9 24.3 15.7 31.9 23.3 17.7 29.2 21.8 21.9 24.5 23.1 18.6 21.9 21.3 22.6 24.9 27.5 27.7 24.6 23.1 29.4 20.7 24.2 19.6 23.8 22.4 58.8 27.0 22.5 23.3 21.3 21.8 26.5 51.6 23.2 30.3 22.4 22.4 25.7 26.2 22.8 19.8 25.4 23.3 27.3 18.7 19.4 15.7 43.6 39.0 35.9 22.1 13.8 24.0 23.3 25.6 25.9 29.7 33.1 39.2 28.6 39.0 16.4 21.0 33.9 39.5 38.3 42.4 13.6 14.3 52.7 10.4 37.9 23.6 45.8 11.7 22.0 40.6 27.3 76.2 32.0 51.7 25.6 27.1 14.4 55.0 16.3 51.5 26.8 32.7 31.5 31.7 25.6 27.6 37.7 30.0 21.9 42.2 38.9 28.1 18.0 30.1 31.6 27.1 20.4 37.9 26.6 62.8 38.4 15.8 27.5 31.8 23.3 19.7 22.2 16.1 27.3 19.4 19.8 15.7 15.5 25.4 18.9 16.0 15.0 12.1 18.7 25.2 21.1 16.4 15.7 23.2 31.3 26.3 32.8 21.8 21.9 21.3 22.6 29.4 23.2 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58197920 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavourable (1.40e-5)" "prognostic unfavourable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 22.8 14.5 15.2 15.2 14.2 14.8 33.5 11.1 17.0 20.4 22.2 12.6 15.1 11.7 19.0 21.4 20.2 15.8 18.7 19.7 12.8 11.5 16.2 21.1 20.0 28.7 10.8 13.9 23.9 28.1 34.3 14.4 29.1 11.6 22.0 15.0 12.9 15.6 15.2 25.4 50.5 18.0 18.8 11.2 26.6 21.1 69.1 10.2 44.3 25.9 12.0 18.5 28.9 33.8 8.9 8.0 8.7 14.1 12.8 14.5 11.7 18.5 20.8 16.1 19.2 22.8 32.3 28.5 14.4 22.1 28.6 18.1 39.0 15.8 33.8 20.2 20.1 21.8 29.0 25.9 36.4 11.1 15.8 18.6 14.0 34.8 35.1 29.9 19.1 31.6 38.8 21.6 38.6 29.9 37.3 9.9 17.3 12.9 29.5 24.8 25.9 24.2 40.2 32.9 17.8 21.2 20.6 13.7 15.5 34.4 16.1 27.4 10.1 25.1 24.5 19.6 23.3 15.4 19.1 22.6 18.6 48.0 17.4 20.7 18.2 8.7 14.1 7.4 11.9 12.4 13.5 8.9 14.2 11.6 8.0 7.8 14.3 14.5 0.7 12.8 10.8 7.6 10.7 11.7 15.2 14.2 11.1 17.0 12.8 11.5 10.8 13.9 11.6 10.2 CSNK2A3 CSNK2A1P ENSG00000254598 "Casein kinase 2 alpha 3" Q8NEV1 11 11351942-11353357 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 5.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA059206, HPA061698" Uncertain Approved Nucleoplasm Nucleoplasm "HPA059206: , HPA061698: " "unprognostic (3.10e-2)" "unprognostic (3.39e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.82e-2)" "unprognostic (1.60e-1)" "unprognostic (6.25e-4)" "unprognostic (4.36e-2)" "unprognostic (5.42e-2)" "unprognostic (1.88e-1)" "unprognostic (5.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.38e-2)" 4.6 1.6 1.3 2.8 1.3 0.6 1.9 1.6 5.5 2.8 3.8 0.5 2.1 3.4 1.8 3.8 3.4 1.1 1.6 2.3 1.5 1.2 5.4 3.0 3.7 1.0 1.1 0.7 2.0 1.4 0.6 1.7 2.9 2.0 2.2 0.7 2.1 1.7 3.6 5.3 1.9 2.9 2.9 1.2 0.9 1.3 3.5 0.3 3.6 1.6 1.8 2.7 1.8 1.3 0.7 0.9 1.1 0.6 0.8 1.0 1.2 5.5 1.1 0.2 2.1 0.0 0.0 0.7 0.5 0.3 0.3 0.3 0.0 0.3 0.0 0.4 0.0 1.8 0.9 0.8 0.0 0.2 0.3 0.0 0.2 0.5 0.0 0.2 0.3 0.6 0.4 0.0 0.6 0.0 0.4 0.8 0.7 0.6 1.3 0.7 1.7 3.0 0.9 0.2 1.0 0.6 1.0 0.4 1.2 1.6 3.1 0.6 1.2 0.4 0.7 0.9 1.1 0.4 0.6 0.4 0.9 0.8 2.6 0.2 2.5 0.7 0.5 1.1 0.6 0.6 0.9 0.7 0.4 0.7 0.9 0.7 1.0 0.3 0.1 0.8 0.6 0.7 0.7 1.2 1.3 1.3 1.6 5.5 1.5 1.2 1.1 0.7 2.0 0.3 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell line enhanced" "Detected in many" "HMC-1: 38.7;HUVEC TERT2: 21.9;RPTEC TERT1: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome Centrosome "CAB037302: AB_1078622, HPA040472: , HPA048436: " "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.2 8.8 6.1 0.2 0.1 14.0 1.2 1.7 7.2 8.1 2.6 0.1 0.1 1.8 0.3 17.0 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.8 0.0 38.7 0.5 2.9 1.3 0.5 21.9 6.6 3.7 6.0 0.5 2.6 0.0 9.9 0.0 0.7 7.8 0.0 20.0 18.2 4.0 4.5 0.0 1.8 7.7 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell line enhanced" "Detected in many" "ASC diff: 10.0;HaCaT: 8.3;HMC-1: 17.0;MCF7: 8.6" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA071581: " "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favourable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.6 1.4 10.0 0.4 0.1 1.9 6.0 1.0 1.1 0.8 1.4 0.2 0.6 6.0 8.3 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.0 1.0 7.2 0.3 0.2 0.6 0.4 0.1 0.7 8.6 0.0 0.3 0.6 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Approved Nucleoplasm Nucleoplasm "HPA028569: AB_10794319, HPA064809: " "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favourable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.5 20.3 12.7 16.0 9.5 10.8 19.6 35.3 28.5 28.9 19.1 37.4 7.7 14.2 17.3 30.9 20.4 12.4 20.0 10.5 20.7 20.6 5.7 24.9 21.4 30.3 13.7 21.5 24.5 25.0 26.1 15.1 23.9 18.0 24.7 17.5 16.6 13.5 10.3 19.7 16.3 17.0 18.8 13.2 17.4 20.1 20.1 14.0 23.7 28.7 20.2 20.6 10.8 44.6 37.1 16.8 33.2 44.0 27.6 22.6 16.4 29.6 14.4 19.8 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 DBT ENSG00000137992 "Dihydrolipoamide branched chain transacylase E2" P11182 1 100186919-100249834 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026481, HPA026485, HPA026533" Enhanced Supported Mitochondria Mitochondria "HPA026481: AB_1847504, HPA026485: AB_1847505, HPA026533: AB_1847506" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (3.67e-2)" "unprognostic (5.29e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "unprognostic (3.88e-2)" "unprognostic (1.65e-2)" "unprognostic (6.01e-2)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.90e-1)" "prognostic favourable (8.79e-12)" "unprognostic (1.63e-1)" "unprognostic (3.77e-1)" "unprognostic (9.67e-2)" "unprognostic (9.92e-2)" 8.6 14.1 8.3 5.0 13.6 3.9 8.7 8.0 11.8 8.5 7.8 7.9 13.6 6.6 9.8 6.6 13.6 8.6 5.2 18.1 8.6 7.3 22.2 29.1 8.0 5.3 10.2 8.2 9.1 13.7 10.2 12.3 7.3 9.4 12.0 7.6 5.2 11.3 8.3 15.7 8.1 5.8 11.2 8.6 6.0 12.6 5.7 8.2 9.6 13.0 8.7 6.3 12.8 7.7 4.4 2.6 3.3 3.1 4.0 5.0 2.1 11.5 5.7 5.2 10.6 11.6 10.1 12.2 7.9 6.4 7.1 8.6 11.8 4.4 10.5 11.6 4.7 10.4 11.6 8.4 8.9 11.1 6.7 7.6 10.9 5.8 9.9 10.0 3.6 9.8 9.3 5.8 9.1 6.6 12.2 11.5 5.6 2.6 8.3 3.2 11.0 11.4 8.1 19.2 7.9 7.8 10.5 9.2 5.7 17.5 15.6 13.2 12.3 6.2 7.6 7.0 4.7 8.9 7.1 8.1 8.2 5.4 8.3 6.2 3.1 3.3 2.2 1.8 4.9 3.1 5.0 4.4 4.4 4.2 2.2 4.1 4.5 4.2 2.1 4.0 2.7 2.6 3.4 2.1 8.3 13.6 8.0 11.8 8.6 7.3 10.2 8.2 9.4 8.2 DCAF1 "KIAA0800, MGC102804, VPRBP" ENSG00000145041 "DDB1 and CUL4 associated factor 1" Q9Y4B6 3 51395867-51500002 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036142, HPA052445, HPA053203" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA036142: AB_10669666, HPA052445: , HPA053203: " "unprognostic (7.51e-2)" "unprognostic (3.19e-1)" "unprognostic (3.71e-3)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (9.75e-2)" "unprognostic (2.58e-2)" "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.15e-1)" "unprognostic (2.89e-2)" "unprognostic (2.21e-2)" "prognostic favourable (7.45e-5)" "unprognostic (5.49e-2)" "unprognostic (5.00e-1)" "unprognostic (6.81e-2)" "unprognostic (1.64e-1)" 13.3 12.5 11.5 16.3 12.3 12.9 12.2 17.9 12.5 9.6 10.3 11.0 12.5 7.6 13.1 10.1 11.3 9.2 8.4 8.8 9.6 6.8 11.0 11.1 10.9 13.0 11.1 9.1 11.9 11.1 24.8 12.9 15.4 10.3 10.1 10.9 8.6 12.5 11.8 28.1 14.1 11.8 10.4 9.1 11.9 10.7 50.7 10.9 18.5 14.2 7.6 16.7 12.5 16.5 7.3 6.4 3.3 6.0 7.3 10.7 6.2 10.7 13.2 12.9 11.6 11.6 9.3 12.2 12.1 9.1 13.1 12.9 14.4 10.5 26.2 6.7 9.5 9.5 24.2 10.8 17.0 18.2 12.0 22.4 18.1 12.4 8.5 29.2 16.3 6.1 12.6 16.9 12.4 10.1 13.1 17.1 10.2 10.9 22.3 11.9 13.5 14.6 9.5 13.8 17.3 10.2 16.8 6.7 11.9 13.3 12.4 7.3 8.4 12.4 12.6 10.8 14.5 17.7 18.5 11.6 15.7 27.0 12.5 20.1 8.8 3.2 4.0 3.3 9.4 4.5 10.7 7.1 8.1 8.0 6.4 7.3 8.9 7.3 1.0 7.3 6.0 5.2 8.7 6.2 11.5 12.3 17.9 12.5 9.6 6.8 11.1 9.1 10.3 10.9 DCK ENSG00000156136 "Deoxycytidine kinase" P27707 4 70992538-71030914 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.9" "Cell line enhanced" "Detected in all" "Daudi: 59.7;U-698: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059609, HPA062773" Enhanced Supported Nucleoplasm Nucleoplasm "HPA059609: , HPA062773: " "unprognostic (9.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.24e-3)" "unprognostic (4.77e-2)" "unprognostic (3.95e-1)" "unprognostic (6.45e-2)" "prognostic unfavourable (6.90e-7)" "unprognostic (3.04e-2)" "unprognostic (7.19e-2)" "unprognostic (8.28e-2)" "unprognostic (4.51e-1)" "unprognostic (1.33e-1)" "unprognostic (3.37e-2)" "unprognostic (4.47e-2)" "unprognostic (6.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.27e-2)" 8.0 8.3 11.9 30.9 16.8 17.2 6.9 11.4 14.8 5.6 8.6 10.4 2.6 7.6 7.5 4.4 8.8 5.5 6.1 5.5 12.3 13.1 5.8 4.8 9.7 42.8 11.7 10.3 6.0 5.0 3.6 4.2 7.9 11.1 5.9 10.4 6.4 6.3 4.0 6.8 7.9 12.4 7.5 17.6 17.5 8.2 5.6 8.6 80.9 8.3 3.8 39.9 9.5 6.5 27.9 34.2 17.5 12.7 18.5 24.9 25.1 6.6 4.4 9.7 5.7 3.0 5.3 5.6 17.2 6.4 13.6 11.4 2.9 14.5 59.7 7.4 7.1 3.9 8.6 5.4 18.4 12.6 5.3 12.3 5.1 4.5 3.1 24.6 15.9 2.7 6.6 8.3 5.0 7.7 4.9 22.7 15.5 3.8 30.4 9.7 4.7 5.4 25.8 19.7 4.7 6.8 4.6 8.6 9.2 6.4 12.7 7.5 5.7 12.9 6.2 15.4 11.6 12.9 9.2 8.6 5.6 48.4 10.7 15.4 11.4 13.1 10.7 17.5 16.2 12.7 20.3 27.9 21.8 20.0 14.3 26.4 23.4 23.5 5.4 18.5 12.1 34.2 24.9 25.1 11.9 16.8 11.4 14.8 12.3 13.1 11.7 10.3 11.1 8.6 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell line enhanced" "Detected in some" "ASC diff: 17.3;ASC TERT1: 16.4;fHDF/TERT166: 13.3;HAP1: 10.3;HSkMC: 15.1;NTERA-2: 21.4" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: , HPA015655: " "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 17.3 16.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 13.3 0.0 10.3 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 15.1 7.5 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 21.4 0.2 0.0 1.2 0.0 0.6 0.0 4.3 2.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.5 4.4 0.7 0.1 0.0 0.0 1.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell line enhanced" "Detected in many" "AF22: 18.2;BJ hTERT+: 19.0;fHDF/TERT166: 8.3" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favourable (3.25e-4)" "prognostic favourable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.2 2.8 0.0 0.9 0.3 8.2 19.0 2.7 0.6 0.1 0.0 0.0 0.3 8.3 0.0 2.6 0.0 3.4 3.7 1.6 0.0 4.7 0.0 3.9 0.5 0.5 0.5 0.0 1.6 0.2 0.9 0.0 0.0 1.9 0.1 0.3 0.0 0.3 1.0 0.0 2.1 0.7 0.0 0.8 7.0 6.6 3.4 2.5 0.8 0.0 0.0 1.6 2.5 1.0 1.6 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712422-36764349 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 10.0;testis: 8.0" "Cell line enhanced" "Detected in some" "NTERA-2: 3.3;SCLC-21H: 3.2;SH-SY5Y: 2.6;U-2 OS: 1.8;U-2197: 2.5" "Cancer enhanced" "Detected in single" "testis cancer: 1.2" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040685 Approved "HPA040685: " "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" 1.1 0.4 2.6 1.4 10.0 0.3 0.1 0.1 2.3 0.5 0.2 0.3 0.0 0.5 0.3 0.1 0.1 0.2 0.6 0.9 1.4 0.9 0.0 0.1 0.3 0.2 0.6 0.0 0.0 0.2 0.4 1.8 1.1 0.4 0.3 0.3 1.3 1.7 0.2 2.7 0.4 0.4 0.9 0.7 0.1 0.0 8.0 3.2 0.0 0.9 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.2 3.2 2.6 0.1 0.3 0.0 0.0 0.4 0.3 0.0 1.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 10.0 0.1 2.3 1.4 0.9 0.6 0.0 0.4 3.2 DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 18.2;skin 1: 6.8;testis: 10.7" "Cell line enhanced" "Detected in some" "HaCaT: 4.8;HeLa: 4.0;RPMI-8226: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA060314 Uncertain "HPA060314: " "unprognostic (1.44e-1)" "unprognostic (7.66e-2)" "unprognostic (3.77e-2)" "unprognostic (1.05e-4)" "unprognostic (3.58e-2)" "unprognostic (8.75e-4)" "unprognostic (1.46e-2)" "unprognostic (2.66e-1)" "unprognostic (6.01e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.89e-2)" "unprognostic (8.33e-15)" "unprognostic (7.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.38e-1)" "unprognostic (1.23e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.7 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.0 18.2 0.7 0.1 0.1 6.8 1.6 0.1 0.1 0.2 0.4 10.7 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.8 0.8 0.9 1.2 0.0 1.0 0.1 1.5 0.7 2.7 1.5 0.1 0.0 1.0 0.5 0.0 0.0 0.0 0.7 3.2 1.5 0.5 0.0 4.8 0.0 0.0 0.0 1.2 0.4 0.4 4.0 0.3 0.0 1.1 0.6 0.0 0.2 0.0 0.0 0.0 1.1 2.3 0.0 1.0 0.0 0.3 0.2 2.2 0.0 1.1 5.4 0.0 0.8 0.9 1.8 0.6 1.8 0.2 3.4 0.1 0.0 0.3 0.2 0.8 0.4 0.9 0.8 0.3 0.7 1.6 0.0 0.0 0.2 0.9 0.1 0.0 0.0 0.8 0.4 0.2 0.3 0.0 1.0 0.2 0.2 0.0 1.2 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 31.2;HBEC3-KT: 24.0;RT4: 31.9;T-47d: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" 2100000 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favourable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 6.7 11.3 23.5 7.9 36.2 2.2 12.5 6.8 42.2 9.7 25.2 57.4 17.6 16.8 7.7 10.5 30.5 31.7 18.9 8.7 27.8 20.8 19.8 3.5 13.2 3.1 55.7 19.8 11.3 20.9 28.2 14.6 13.3 34.7 17.7 14.9 4.0 28.3 20.5 9.1 41.3 32.1 3.1 43.2 5.1 52.2 5.1 37.0 8.7 20.9 10.5 7.6 16.3 16.6 1.8 0.4 0.0 0.2 0.0 1.8 0.9 19.3 6.4 9.1 1.9 0.6 0.8 5.6 0.5 0.1 0.2 0.0 8.6 10.3 0.1 10.8 1.7 31.2 1.9 24.0 0.1 10.7 3.4 0.0 5.8 2.2 1.8 0.0 0.4 1.2 12.4 0.1 0.2 0.7 5.6 0.2 1.3 12.2 0.6 0.0 1.5 1.3 1.3 6.8 0.7 4.6 31.9 1.6 0.8 1.8 14.4 7.0 35.8 0.2 1.4 4.5 4.2 0.4 4.5 0.2 0.0 0.8 2.9 0.0 3.9 0.0 0.2 0.0 1.1 0.0 0.8 0.4 0.2 0.7 0.4 1.8 1.2 1.8 0.0 0.0 0.0 0.4 0.0 0.9 23.5 36.2 6.8 25.0 27.8 20.8 55.7 19.8 34.7 37.0 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787400 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 60.6;ASC TERT1: 59.9;BJ hTERT+: 44.3;fHDF/TERT166: 31.7;HSkMC: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 5 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Supported "Plasma membrane,Actin filaments" 850000 "Plasma membrane, Actin filaments" "HPA070112: " "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 42.1 43.5 4.7 10.9 6.9 0.2 15.6 7.9 7.1 30.3 30.4 9.0 18.6 3.3 24.2 17.7 25.0 13.4 16.6 15.4 7.9 4.7 4.0 3.3 8.9 5.1 12.9 3.4 26.4 2.2 2.1 4.0 6.6 12.7 21.8 9.1 30.7 6.4 19.3 5.2 6.1 10.1 34.3 19.7 3.4 14.1 8.3 7.5 0.0 8.6 12.8 4.1 29.0 18.3 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 16.0 60.6 59.9 0.2 23.6 44.3 10.3 14.9 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 14.1 12.7 0.1 0.0 0.0 0.0 26.3 0.0 0.0 42.5 0.1 18.2 0.4 11.8 0.1 5.0 9.4 0.0 0.0 0.0 0.1 0.1 0.0 6.7 0.1 0.0 0.0 0.0 9.7 0.0 0.0 0.8 0.0 0.0 0.6 16.5 3.6 8.3 3.2 0.7 1.3 0.0 14.9 0.0 16.7 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 4.7 6.9 7.9 7.1 7.9 4.7 12.9 3.4 12.7 7.5 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "intestine: 161.0" "Cell line enhanced" "Detected in many" "Hep G2: 15.8;PC-3: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Endoplasmic reticulum" "Endoplasmic reticulum" Nucleoli "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 11.8 18.5 3.6 5.7 4.7 6.4 6.8 6.6 5.6 3.3 60.2 4.0 6.4 44.7 3.9 3.6 5.5 3.1 7.9 6.3 3.7 2.7 6.7 14.4 3.8 3.1 4.1 2.7 3.3 3.9 5.0 4.0 4.3 3.6 3.4 6.3 4.1 5.9 4.3 10.0 4.8 161.0 3.6 2.6 5.3 5.7 10.7 4.2 5.1 3.8 6.2 5.0 4.7 3.4 0.7 2.2 2.8 2.0 0.3 1.7 0.8 3.8 4.1 1.9 3.6 3.2 1.3 2.3 2.7 2.7 2.6 1.8 9.7 2.6 1.5 10.6 1.7 3.3 1.6 3.7 0.5 2.8 4.0 2.8 3.3 15.8 2.3 0.7 2.9 1.8 2.9 1.6 1.9 2.0 2.2 3.5 1.7 3.2 4.8 3.1 0.9 17.6 6.2 0.8 2.5 2.4 2.1 2.0 3.4 3.6 4.4 1.8 2.5 2.7 1.6 1.4 4.9 2.8 2.2 2.0 0.4 0.6 1.4 4.9 2.3 0.0 2.0 2.8 1.2 1.3 1.7 0.7 0.9 1.1 2.2 0.5 0.7 0.3 2.3 0.3 1.7 1.1 0.7 0.8 3.6 4.7 6.6 5.6 3.7 2.7 4.1 2.7 3.6 4.2 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 104.3;blood: 68.9;liver: 81.3" "Cell line enhanced" "Detected in many" "ASC diff: 33.6;HDLM-2: 24.3;Hep G2: 25.4" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "eosinophil: 26.3;neutrophil: 68.9" "Lineage enriched" "Detected in many" 16 "granulocytes: 68.9" "Low region specificity" "Detected in all" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavourable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 104.3 1.3 1.9 12.5 6.8 1.7 30.4 0.1 4.2 1.0 11.8 0.6 0.4 3.6 0.5 0.6 6.3 0.7 6.3 6.0 1.0 1.2 1.0 81.3 1.8 16.1 0.6 1.2 0.6 1.3 0.4 0.6 0.5 1.0 1.0 1.4 1.2 9.9 0.6 1.3 34.1 8.1 0.9 0.6 3.7 3.3 13.6 0.5 1.0 2.4 3.9 4.5 4.0 2.7 1.5 1.1 68.9 4.2 0.0 0.0 0.9 5.1 2.5 0.1 4.5 33.6 2.7 0.4 0.4 0.6 0.6 0.4 18.5 5.4 8.2 6.8 0.1 0.2 0.7 2.6 1.8 24.3 0.4 0.5 1.7 25.4 0.3 2.9 2.9 11.2 13.8 3.0 4.3 0.4 0.4 11.2 0.2 3.3 1.9 6.3 1.4 12.1 0.0 0.0 9.6 0.4 14.2 9.2 0.5 4.7 0.7 1.2 1.8 10.4 0.6 5.8 2.8 0.1 3.5 6.6 14.6 11.0 4.2 9.3 10.0 3.0 4.2 26.3 0.0 0.8 0.0 1.5 0.0 0.0 1.1 1.2 0.0 0.0 68.9 0.0 0.8 0.3 0.0 0.9 1.9 6.8 0.1 4.2 1.0 1.2 0.6 1.2 1.0 0.5 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.1" "Cell line enhanced" "Detected in many" "HBEC3-KT: 42.2;hTERT-HME1: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria Vesicles "Nucleoplasm, Mitochondria" "HPA041645: , HPA045462: " "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 4.9 4.7 7.1 31.8 8.2 9.7 4.8 6.0 10.8 8.4 13.4 3.6 3.1 20.5 6.9 4.1 42.0 4.9 7.9 3.8 4.6 2.4 3.9 1.5 7.6 28.6 2.1 4.1 4.9 6.4 6.2 3.1 10.2 3.3 10.6 11.0 4.1 16.2 5.3 1.0 33.0 27.2 5.7 3.7 23.1 4.8 4.4 2.6 117.1 4.5 9.6 57.0 13.0 15.1 7.6 4.0 5.4 2.8 5.2 30.2 10.9 6.7 4.3 3.0 4.0 7.5 9.8 0.9 15.2 15.6 6.0 4.4 2.0 11.5 3.8 3.6 10.1 12.4 3.2 42.2 7.2 3.2 0.7 6.1 9.1 1.1 6.5 1.9 6.0 8.4 22.7 8.3 44.8 12.2 0.7 5.9 16.1 0.7 12.5 2.4 0.6 5.1 5.8 1.0 0.6 14.2 19.5 0.5 1.7 5.0 0.2 0.5 2.7 2.0 10.9 3.9 2.8 0.8 0.5 0.7 0.3 9.2 4.7 5.2 1.1 5.2 2.8 5.4 6.5 2.0 11.7 7.6 24.3 11.7 4.0 6.4 30.2 18.1 5.2 5.2 1.2 4.0 26.7 10.9 7.1 8.2 6.0 10.8 4.6 2.4 2.1 4.1 3.3 2.6 DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 37.7" "Cell line enhanced" "Detected in some" "AF22: 2.7;fHDF/TERT166: 5.5;hTEC/SVTERT24-B: 2.1;SCLC-21H: 2.8;SH-SY5Y: 2.1;U-266/70: 7.4" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020321 Supported "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" 1.1 5.2 11.5 1.1 37.7 0.8 0.8 1.3 34.0 4.9 1.6 1.4 0.0 0.9 6.1 0.9 1.6 2.7 1.3 1.4 10.5 4.3 2.6 1.1 0.8 0.8 2.2 11.3 0.8 0.9 0.8 1.8 0.7 4.8 1.1 1.7 0.0 0.9 0.9 1.2 0.9 1.2 3.1 3.5 0.8 0.8 0.9 7.9 0.0 0.9 0.0 0.8 1.5 0.6 0.7 0.6 1.3 0.3 0.6 0.5 0.1 0.1 0.0 2.7 0.1 0.0 0.2 0.1 0.0 1.2 0.0 0.3 0.2 0.0 0.1 0.0 5.5 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 2.8 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 7.4 0.0 0.0 0.1 0.1 0.1 0.7 0.3 0.3 0.5 0.2 0.4 0.3 0.5 0.2 0.1 0.7 0.5 0.4 1.3 0.6 0.2 0.6 0.2 0.1 11.5 37.7 1.3 19.1 10.5 4.3 2.2 11.3 4.8 7.9 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354507-233472104 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 22.1;U-698: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol Cytosol "HPA027530: , HPA049101: " "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavourable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.9 3.6 10.0 10.9 12.4 26.3 5.3 34.3 7.9 3.7 7.8 8.9 12.4 8.1 5.8 12.6 2.7 5.5 8.0 6.4 9.6 4.3 3.1 3.3 9.3 14.0 11.7 4.3 8.6 3.0 2.3 3.7 8.9 7.2 6.0 8.4 6.2 4.9 8.0 25.4 2.9 10.9 7.3 11.1 10.3 19.4 17.4 8.3 4.5 7.6 1.3 13.5 5.6 10.1 6.6 1.0 5.9 2.0 1.8 3.4 2.5 3.2 8.0 4.7 3.0 2.2 2.2 7.2 1.9 1.7 1.8 1.9 13.8 3.2 5.8 1.0 3.0 3.2 5.1 2.3 3.0 8.7 4.8 8.1 22.1 4.7 2.8 7.0 8.8 3.1 4.9 2.3 4.4 2.0 5.7 1.3 1.9 3.1 5.7 7.3 2.5 4.5 11.4 8.7 4.7 1.4 3.8 7.2 5.2 6.5 3.5 3.4 1.5 12.5 1.9 3.9 7.2 2.3 5.8 4.7 2.9 22.4 3.4 10.9 3.0 1.7 2.0 5.9 3.3 0.8 1.6 6.3 1.0 2.9 1.0 6.6 2.3 3.4 2.0 1.8 1.4 0.6 0.5 2.5 10.0 12.4 34.3 7.9 9.6 4.3 11.7 4.3 7.2 8.3 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834099-56869567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favourable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 7.8 4.9 7.8 8.3 17.7 5.5 5.2 21.3 18.6 9.5 7.4 4.4 5.6 5.4 13.3 8.9 5.0 8.2 9.4 4.9 7.4 9.2 4.2 4.9 8.1 9.3 5.6 10.0 7.3 6.5 9.5 14.5 5.5 9.9 8.9 7.0 17.4 4.3 7.3 2.4 3.4 7.1 9.3 6.8 12.7 6.4 12.5 5.4 14.5 8.3 2.5 8.6 6.5 15.3 2.4 2.4 1.2 0.8 1.9 4.5 0.8 1.6 1.6 1.5 0.1 0.2 0.5 0.7 2.8 2.3 1.9 2.3 3.7 2.0 2.4 3.5 1.5 2.0 3.6 1.5 4.0 7.8 4.6 3.1 3.9 2.4 1.7 6.0 4.5 0.9 2.0 2.0 4.1 2.6 2.5 42.7 2.4 2.4 14.2 3.4 1.1 4.8 4.4 6.2 5.8 1.9 3.7 2.3 1.6 2.3 1.2 0.1 2.6 2.9 2.4 0.5 2.7 0.8 0.4 5.6 11.5 1.6 1.7 3.5 0.1 0.3 0.5 0.0 2.7 0.4 2.0 2.4 1.9 2.3 0.6 0.9 1.9 2.5 1.2 1.9 0.8 2.4 4.5 0.8 7.8 17.7 21.3 18.6 7.4 9.2 5.6 10.0 9.9 5.4 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362237 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.4" "Cell line enhanced" "Detected in some" "HDLM-2: 19.8;HL-60: 6.3;U-266/84: 7.5;U-87 MG: 12.5;U-937: 5.9" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 4.2;eosinophil: 2.4;intermediate monocyte: 2.4;myeloid DC: 2.9;neutrophil: 5.3;non-classical monocyte: 2.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.9;granulocytes: 5.3;monocytes: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 3.1 6.9 13.4 3.1 7.1 14.5 1.9 53.4 23.1 2.7 3.5 6.2 1.1 3.0 1.9 14.6 8.5 7.7 2.2 15.0 15.3 7.4 3.1 2.1 4.3 2.1 7.4 11.3 2.0 1.6 4.7 7.5 13.5 25.2 3.1 2.1 7.8 1.9 4.0 2.4 1.4 2.7 5.3 5.6 2.0 3.3 1.2 7.1 0.0 2.5 0.0 2.1 4.8 2.4 0.6 2.9 5.3 4.2 0.0 0.0 1.3 2.6 4.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 2.3 0.0 0.2 0.0 0.0 0.0 19.8 0.0 2.6 0.0 2.9 0.0 6.3 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.3 0.1 0.1 2.2 0.4 1.2 1.4 0.0 2.2 0.0 0.0 0.5 0.0 0.8 0.0 1.6 0.1 4.1 0.0 0.0 0.7 2.0 2.4 0.0 7.5 0.0 12.5 5.9 2.3 0.0 4.2 2.4 0.0 2.4 0.0 0.6 0.0 0.0 2.9 0.3 0.0 0.0 5.3 0.0 2.8 0.5 0.0 1.3 13.4 7.1 53.4 14.7 15.3 7.4 7.4 11.3 25.2 7.1 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039533, HPA040355" Uncertain "HPA039533: AB_10795145, HPA040355: AB_10796452" "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 4.9 2.8 3.3 4.9 12.7 2.3 8.3 9.6 6.2 5.2 6.4 3.4 7.9 3.1 9.4 14.0 5.2 5.9 6.8 10.2 9.0 2.7 6.0 6.8 9.5 4.0 3.5 4.0 4.3 4.2 1.4 3.5 8.9 3.6 4.6 6.9 5.5 7.7 4.8 5.8 6.2 5.1 8.3 3.5 6.1 4.0 7.0 4.3 2.2 4.3 2.0 2.9 8.1 6.0 1.4 1.5 4.3 1.3 0.7 1.7 0.2 4.9 5.7 4.7 3.7 1.8 4.0 0.5 3.2 2.4 2.0 2.6 0.5 4.2 3.8 3.9 3.3 10.8 4.0 7.0 3.2 3.2 11.3 6.9 3.0 0.4 2.3 2.8 1.9 1.5 7.1 3.9 16.1 9.2 2.7 2.6 3.5 4.7 2.9 1.6 1.9 3.9 4.6 3.8 2.6 6.9 14.7 2.7 2.5 2.9 3.7 2.7 3.3 8.1 9.0 4.0 3.5 4.2 4.2 1.4 1.3 4.4 2.1 2.6 2.8 2.4 1.3 0.6 1.1 0.9 1.2 0.8 1.7 1.7 0.3 1.4 1.0 1.6 4.3 0.7 0.7 1.5 1.1 0.2 3.3 12.7 9.6 6.2 9.0 2.7 3.5 4.0 3.6 4.3 DGKI DGK-IOTA ENSG00000157680 "Diacylglycerol kinase iota" O75912 7 137381037-137847092 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;thyroid gland: 32.1" "Cell line enhanced" "Detected in some" "BJ: 4.0;hTEC/SVTERT24-B: 4.1;SCLC-21H: 6.7;U-2197: 18.5;U-87 MG: 6.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-3)" "unprognostic (1.76e-1)" "unprognostic (6.08e-2)" "unprognostic (1.42e-1)" "unprognostic (9.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.09e-1)" "unprognostic (9.01e-2)" "unprognostic (8.74e-2)" "unprognostic (4.46e-2)" "unprognostic (5.98e-5)" "unprognostic (2.85e-3)" "unprognostic (1.85e-1)" "unprognostic (1.26e-2)" "unprognostic (1.73e-3)" 1.5 1.3 5.0 1.1 19.8 0.7 1.1 11.4 12.7 0.8 0.9 2.6 0.0 0.9 1.4 0.9 0.9 0.9 1.9 5.0 4.6 3.3 1.7 0.7 0.8 0.8 2.8 9.0 0.8 0.7 0.8 6.0 0.8 6.6 1.0 0.9 10.8 1.0 1.1 0.7 0.9 0.9 2.7 2.5 0.8 0.8 1.9 5.8 0.0 32.1 0.0 0.8 1.1 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.9 0.0 4.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.0 4.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 6.7 2.8 0.0 0.0 0.5 0.0 0.0 0.3 1.6 0.6 18.5 0.9 0.1 0.0 0.0 6.9 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.0 19.8 11.4 12.7 4.6 3.3 2.8 9.0 6.6 5.8 DGKK ENSG00000274588 "Diacylglycerol kinase kappa" Q5KSL6 X 50365409-50470738 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "adrenal gland: 9.8;brain: 29.6;pituitary gland: 33.5" "Cell line enriched" "Detected in some" 20 "Hep G2: 27.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "gdT-cell: 2.4;memory CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 25 "T-cells: 2.4" "Region enhanced" "Detected in some" "hypothalamus: 12.9" "Group enriched" "Detected in many" 5 "basal ganglia: 3.5;hypothalamus: 1.8;midbrain: 4.3;pons and medulla: 1.1" "unprognostic (3.99e-1)" "unprognostic (1.18e-1)" "unprognostic (4.18e-3)" "unprognostic (1.23e-1)" "unprognostic (5.83e-3)" "unprognostic (9.58e-2)" "unprognostic (2.41e-2)" "unprognostic (1.62e-2)" "unprognostic (2.06e-1)" "unprognostic (4.28e-3)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.49e-2)" "unprognostic (4.64e-3)" 0.1 9.8 0.0 0.0 29.6 0.2 0.3 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 DGKQ "DAGK, DAGK4, DAGK7" ENSG00000145214 "Diacylglycerol kinase theta" P52824 4 958887-986895 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026797, CAB033835" Uncertain "CAB033835: AB_2091307, HPA026797: AB_10600902" "unprognostic (7.39e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (3.37e-1)" "unprognostic (6.39e-2)" "unprognostic (2.90e-2)" "unprognostic (1.06e-1)" "unprognostic (6.45e-2)" "unprognostic (1.06e-2)" "unprognostic (9.77e-2)" "unprognostic (3.08e-3)" "unprognostic (4.38e-2)" "unprognostic (2.65e-2)" "unprognostic (1.65e-3)" 6.4 9.3 15.9 10.7 13.8 10.4 6.9 21.6 17.4 5.4 14.7 7.9 6.9 27.0 6.3 3.8 7.9 5.3 10.3 4.5 15.0 12.1 8.4 8.9 6.9 12.3 9.7 12.3 5.1 9.8 5.5 8.2 4.4 10.2 7.0 8.4 6.7 12.1 5.8 3.7 13.0 28.0 5.9 5.2 12.7 8.6 6.8 7.7 9.1 6.7 3.8 8.7 6.6 7.0 1.3 1.9 4.0 1.4 5.3 5.0 1.8 4.2 6.8 3.0 10.1 3.6 3.0 11.2 8.1 4.6 4.6 4.6 4.9 8.4 5.7 6.8 5.1 4.9 1.7 5.6 1.1 4.4 5.3 8.7 6.3 8.5 6.3 3.7 11.7 5.7 9.6 3.8 1.8 5.6 6.6 0.7 3.5 6.3 7.7 21.7 5.3 11.7 12.5 0.9 0.6 5.0 5.9 1.9 5.1 2.8 3.2 8.4 7.5 9.2 8.1 8.0 3.8 9.0 5.3 15.6 6.6 4.3 6.9 8.1 7.2 4.0 1.4 2.9 5.0 1.1 2.3 1.1 1.8 4.1 0.9 1.3 1.9 3.4 0.9 5.3 1.1 1.9 1.1 1.8 15.9 13.8 21.6 17.4 15.0 12.1 9.7 12.3 10.2 7.7 DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA051336: " "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavourable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" 8.6 6.7 34.5 11.8 27.4 28.0 6.8 22.6 50.7 7.5 7.4 8.5 2.5 21.0 6.1 4.3 7.1 6.3 6.7 16.0 48.0 9.2 5.3 3.3 8.3 20.7 9.4 26.7 5.0 17.3 7.0 18.6 8.4 7.5 5.9 4.2 4.8 24.1 7.0 42.8 8.3 23.2 5.6 7.2 15.6 9.9 5.0 7.5 14.2 4.1 9.1 9.9 7.6 5.0 0.9 12.3 11.2 11.8 7.7 7.5 8.1 11.7 10.5 7.1 10.7 3.8 4.2 33.2 9.2 6.9 9.8 8.6 12.5 5.5 15.1 6.7 9.5 13.7 8.6 13.3 3.5 15.1 20.0 9.9 7.7 9.1 6.8 18.6 19.9 5.7 6.3 5.3 7.3 10.7 13.8 9.4 6.9 31.0 17.9 29.2 20.8 16.2 21.4 12.4 6.4 3.0 11.6 49.0 8.3 10.5 35.3 7.2 25.4 23.5 12.0 12.9 14.0 20.3 16.5 6.2 7.0 12.4 17.6 16.9 11.9 11.2 11.8 5.8 7.5 6.1 4.5 0.4 4.7 6.3 12.3 0.9 4.9 5.0 9.8 7.7 5.9 5.9 4.5 8.1 34.5 27.4 22.6 50.7 48.0 9.2 9.4 26.7 7.5 7.5 DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved "HPA034766: AB_10669850, HPA057246: " "unprognostic (3.40e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (4.17e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (4.10e-3)" "unprognostic (5.07e-2)" "unprognostic (1.41e-1)" "unprognostic (9.84e-2)" "prognostic unfavourable (8.69e-7)" "unprognostic (3.86e-1)" "unprognostic (2.21e-2)" "unprognostic (5.98e-2)" "prognostic favourable (7.47e-4)" 23.8 34.8 25.8 26.2 32.3 26.3 33.7 18.4 33.7 26.1 28.0 23.6 24.9 19.4 30.7 40.9 26.6 35.4 28.0 24.5 28.3 26.5 26.7 31.7 24.7 37.2 23.5 22.6 35.5 20.9 11.2 39.9 30.6 27.1 28.6 34.1 25.2 22.5 28.2 14.1 29.2 29.3 25.8 23.5 33.1 23.6 34.3 17.9 41.7 29.0 21.8 44.2 27.2 27.4 43.5 36.4 50.5 31.4 30.0 42.3 31.3 15.7 26.9 27.9 24.8 18.1 19.9 13.7 10.5 21.2 25.4 23.6 34.0 19.1 29.8 10.1 15.5 12.5 31.7 20.5 30.5 16.3 19.1 23.4 10.2 38.4 26.7 21.4 23.8 18.7 19.4 18.6 21.9 17.9 23.8 13.7 29.1 19.2 20.1 37.8 28.3 19.7 25.9 28.0 19.8 20.2 18.4 32.1 31.4 10.3 10.1 27.1 12.2 12.2 16.8 16.3 26.2 14.1 19.0 11.2 10.8 30.0 23.5 23.2 34.6 41.3 27.4 50.5 25.3 31.4 29.8 40.6 31.4 27.9 32.4 43.5 42.3 33.1 22.5 30.0 30.8 36.4 29.3 31.3 25.8 32.3 18.4 33.7 28.3 26.5 23.5 22.6 27.1 17.9 DHDDS "DS, FLJ13102, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471294 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease mutation, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favourable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 31.8 14.4 11.2 10.8 15.9 6.4 15.0 45.9 18.8 10.4 23.1 12.5 8.3 12.2 15.4 21.9 18.9 9.2 10.9 14.8 9.7 10.7 16.2 15.3 9.5 10.3 12.1 15.8 9.8 14.7 23.2 15.5 13.1 20.6 9.6 23.9 22.0 56.9 9.1 10.3 13.1 12.2 11.3 7.6 10.5 14.2 12.9 8.9 9.7 12.1 11.1 16.9 10.6 9.8 11.1 11.2 11.8 19.5 8.1 11.6 8.2 14.7 12.0 8.0 11.0 16.5 13.9 13.8 25.2 15.7 19.5 19.5 18.5 16.2 16.7 15.4 23.5 10.8 10.8 19.7 18.7 10.2 5.7 16.5 29.9 13.6 15.6 18.0 24.4 19.0 11.8 26.9 15.1 24.6 11.8 18.4 17.9 10.1 9.2 7.6 12.6 16.1 11.0 14.2 14.2 10.6 13.9 11.3 9.0 17.0 18.7 11.1 14.1 10.2 31.2 13.6 13.2 25.5 14.3 22.3 29.9 18.0 21.4 22.7 13.2 6.5 13.4 7.1 11.6 19.5 8.4 11.1 7.7 7.5 11.2 9.3 6.5 9.0 11.8 8.1 18.0 9.1 7.3 8.2 11.2 15.9 45.9 18.8 9.7 10.7 12.1 15.8 20.6 8.9 DHPS MIG13 ENSG00000095059 "Deoxyhypusine synthase" P49366 19 12675717-12681902 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hypusine biosynthesis" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014461, HPA029413" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA014461: AB_1847651, HPA029413: AB_10602217" "unprognostic (4.17e-2)" "unprognostic (2.55e-2)" "unprognostic (2.05e-2)" "unprognostic (2.61e-1)" "unprognostic (3.10e-1)" "unprognostic (1.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (1.85e-1)" "unprognostic (3.59e-2)" "unprognostic (1.20e-2)" "unprognostic (4.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.46e-3)" "unprognostic (1.32e-1)" "unprognostic (1.56e-1)" "unprognostic (8.83e-2)" 16.4 30.3 26.9 18.6 31.2 17.0 24.8 43.3 38.8 20.7 25.7 27.5 25.3 23.1 20.9 16.9 21.3 32.3 18.2 26.0 26.3 28.0 23.4 30.3 18.9 24.2 27.5 28.0 34.8 32.0 28.8 32.6 23.2 22.4 24.1 24.5 20.2 24.8 24.6 65.1 25.6 21.5 24.5 29.1 19.5 24.2 13.3 26.3 31.9 24.9 22.9 26.9 23.5 19.2 39.6 29.5 35.8 30.5 27.8 38.1 29.7 20.7 15.3 24.9 13.2 11.2 18.5 5.8 13.3 19.6 25.5 25.7 10.9 10.1 21.5 15.1 14.5 12.6 17.0 18.9 17.6 18.8 12.0 14.3 16.7 14.3 13.8 17.1 22.9 14.9 23.3 15.4 26.6 17.8 13.0 15.3 18.6 41.2 30.5 24.8 19.5 26.1 20.3 9.3 31.0 19.6 11.2 32.4 44.0 13.4 19.5 22.6 18.1 28.7 8.9 30.0 12.2 29.3 20.2 48.9 52.7 14.6 18.4 21.1 28.3 14.5 27.0 35.8 24.7 24.2 25.9 39.6 28.9 25.6 29.0 36.9 38.1 28.1 9.7 27.8 30.5 29.5 34.3 29.7 26.9 31.2 43.3 38.8 26.3 28.0 27.5 28.0 22.4 26.3 DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIM1 dimethyladenosine transferase 1 homolog" Q9UNQ2 5 62387254-62403939 "Enzymes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "HPA042944: " "unprognostic (1.58e-1)" "unprognostic (2.27e-1)" "unprognostic (6.02e-3)" "unprognostic (7.16e-2)" "unprognostic (8.95e-3)" "unprognostic (1.73e-2)" "prognostic unfavourable (6.93e-4)" "unprognostic (8.88e-2)" "unprognostic (1.18e-2)" "unprognostic (1.62e-1)" "unprognostic (5.31e-2)" "unprognostic (3.70e-1)" "prognostic unfavourable (8.90e-12)" "unprognostic (8.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" 16.7 14.0 18.9 16.7 17.0 10.6 18.9 11.5 23.5 18.6 11.8 12.4 11.8 11.0 16.2 11.9 20.1 14.2 15.3 19.7 19.1 17.0 11.9 16.3 11.7 22.5 18.8 8.5 17.8 28.4 8.9 13.4 16.7 12.3 18.8 9.5 10.0 16.1 18.3 17.9 12.2 11.9 24.6 20.2 22.1 10.2 10.7 9.8 16.3 19.0 19.0 19.2 21.7 13.2 7.9 7.7 5.0 5.6 7.0 13.2 6.1 14.4 8.7 15.9 20.8 11.8 15.7 15.9 18.6 7.0 14.4 15.3 14.1 15.5 29.8 17.0 13.8 11.3 10.7 11.0 18.3 21.2 18.7 20.5 11.4 11.7 14.2 16.8 15.8 13.6 8.9 14.0 13.7 12.5 20.7 13.8 14.6 14.5 24.7 25.9 15.4 18.4 16.0 16.1 41.1 13.0 13.4 17.9 15.6 15.9 14.9 15.9 12.0 15.8 13.8 9.9 10.4 14.0 25.4 18.2 18.9 26.9 15.1 30.2 14.6 5.0 3.1 2.3 7.7 5.6 11.7 7.9 10.4 9.3 5.0 6.6 13.2 11.0 0.8 7.0 4.3 7.7 9.3 6.1 18.9 17.0 11.5 14.7 19.1 17.0 18.8 8.5 12.3 9.8 DLAT "DLTA, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112024814-112064390 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 55.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Enhanced Mitochondria Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favourable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavourable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favourable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 14.1 10.7 10.6 8.8 11.9 4.8 10.9 10.5 14.2 6.7 13.3 6.3 7.8 12.4 6.3 8.1 12.2 7.2 6.4 55.4 10.4 13.5 19.1 12.0 6.6 8.7 11.2 9.7 7.9 6.0 15.8 7.8 8.3 13.0 8.3 13.5 7.6 10.4 9.9 41.0 7.2 13.0 6.6 7.3 6.9 8.1 7.3 4.2 12.7 10.7 22.1 8.8 7.5 6.7 9.2 9.1 7.9 8.9 7.2 10.3 8.0 6.0 6.1 8.1 10.8 11.4 8.5 9.7 8.3 4.8 9.2 10.4 19.3 17.8 24.8 16.3 7.6 13.0 16.9 8.9 10.5 8.9 10.5 15.7 6.5 11.9 8.2 19.9 9.0 10.3 9.8 9.2 9.3 8.4 25.7 11.9 10.8 4.7 9.0 23.9 9.5 11.8 14.0 11.0 27.9 16.9 6.4 15.6 9.5 10.0 28.3 6.3 21.0 12.4 5.6 9.2 10.0 9.2 10.6 3.9 6.2 37.6 2.6 21.8 7.2 7.9 6.6 4.7 8.3 8.9 9.5 9.2 8.2 8.9 9.1 7.5 10.3 8.3 0.5 7.2 8.9 7.4 8.8 8.0 10.6 11.9 10.5 14.2 10.4 13.5 11.2 9.7 13.0 4.2 DLST DLTS ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903745 "Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported 800000 "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favourable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 32.2 38.6 12.0 22.7 19.9 28.5 31.3 19.1 25.6 31.2 36.0 18.5 15.9 24.7 26.3 28.3 31.4 19.2 29.7 47.6 10.8 11.8 43.7 45.1 20.8 26.7 13.5 13.7 21.5 27.1 25.8 16.2 25.2 19.7 20.9 26.8 19.2 22.3 20.1 59.2 26.9 43.2 32.9 11.4 20.8 24.3 21.0 10.4 23.5 27.2 49.8 28.4 26.9 21.1 3.8 6.3 8.4 4.3 7.7 5.3 3.2 26.3 27.5 21.0 14.9 33.0 37.5 32.3 34.4 35.0 35.2 33.0 27.0 28.6 26.8 14.7 39.5 29.7 35.4 34.0 37.3 19.4 14.8 21.8 23.0 23.6 34.2 15.5 15.1 38.4 29.8 34.1 42.1 36.3 16.7 18.2 38.2 35.3 18.4 22.0 18.0 25.9 23.5 30.9 14.7 43.7 32.4 25.1 21.2 32.5 43.4 22.4 39.7 22.4 32.1 21.4 28.1 26.2 23.5 12.9 13.4 23.5 31.4 16.1 22.4 8.4 3.0 5.0 5.0 4.3 4.5 3.8 4.5 3.9 4.7 2.7 4.0 5.3 3.0 7.7 3.9 6.3 4.4 3.2 12.0 19.9 19.1 25.6 10.8 11.8 13.5 13.7 19.7 10.4 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769717-45782552 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.6" "Cell line enhanced" "Detected in many" "RH-30: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favourable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 9.0 18.7 5.1 9.7 6.3 1.7 4.9 8.8 6.2 16.5 23.4 4.4 15.6 8.7 21.2 15.0 31.2 13.7 20.3 56.7 5.0 5.3 4.9 2.2 6.5 4.1 4.8 6.5 8.4 33.3 3.1 10.7 6.8 5.6 16.3 3.8 22.0 6.1 19.7 79.6 5.1 11.3 65.1 4.2 5.3 12.0 5.9 4.0 1.1 6.1 36.6 5.0 44.9 8.2 1.5 0.0 0.0 0.8 0.3 2.2 0.0 7.2 10.1 12.0 7.4 8.1 11.3 7.2 16.2 12.0 6.5 6.3 1.2 3.9 2.3 2.4 18.5 10.6 3.4 1.6 2.4 11.3 10.6 0.9 12.6 1.7 7.9 0.1 4.1 16.5 5.7 5.6 2.7 3.0 7.1 5.8 9.4 8.0 1.1 2.7 7.1 2.2 3.7 44.2 3.7 3.5 8.3 6.5 10.3 8.8 18.5 5.2 15.2 3.5 9.1 7.6 7.5 7.2 11.8 11.2 9.6 2.3 6.9 1.0 10.6 0.0 0.0 0.0 2.2 0.8 0.5 0.3 0.7 0.2 0.0 1.5 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.1 6.3 8.8 6.2 5.0 5.3 4.8 6.5 5.6 4.0 DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133345-10231286 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease mutation, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm Nucleoplasm "CAB005876: AB_731983, HPA002694: AB_1847810" "unprognostic (3.51e-1)" "unprognostic (1.20e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-1)" "unprognostic (7.59e-3)" "prognostic unfavourable (1.46e-4)" "unprognostic (2.90e-1)" "unprognostic (4.23e-3)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-3)" "unprognostic (7.81e-3)" "unprognostic (1.73e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" 12.1 7.6 9.8 20.2 10.8 31.9 11.5 27.1 14.4 12.0 8.6 10.0 4.3 8.1 12.1 8.0 12.0 11.5 7.8 8.0 9.3 8.1 6.9 9.2 11.8 29.7 12.5 7.9 11.1 6.2 10.2 8.8 32.5 8.7 8.3 10.7 7.8 9.3 6.5 6.8 10.8 11.3 11.2 9.1 11.0 9.0 19.9 12.6 31.4 9.5 8.8 28.8 11.4 9.7 12.6 19.0 10.2 13.4 25.0 18.2 6.8 24.0 15.2 19.5 16.5 7.3 7.5 41.8 16.3 13.0 23.5 23.6 14.7 13.1 40.3 10.2 10.0 15.9 21.4 12.7 24.1 15.8 31.9 58.4 13.6 7.6 3.1 23.8 23.7 5.0 2.4 20.5 8.1 12.7 23.1 24.9 17.5 16.0 34.7 32.4 25.5 22.2 35.2 20.4 22.2 7.4 15.3 20.8 16.1 19.8 8.9 6.4 9.3 12.1 9.6 39.5 13.5 23.9 24.1 20.4 21.2 47.7 11.5 22.2 30.6 10.2 13.4 3.3 18.2 13.2 15.9 7.9 14.6 12.5 11.3 12.6 16.6 12.3 3.1 25.0 7.9 19.0 12.9 6.8 9.8 10.8 27.1 14.4 9.3 8.1 12.5 7.9 8.7 12.6 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 25.5;REH: 25.1;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavourable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavourable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 7.8 12.4 13.7 12.7 15.5 10.8 8.6 21.6 20.1 9.0 12.7 14.5 7.6 9.1 13.0 12.2 8.0 9.6 8.9 8.2 12.3 6.7 9.4 6.9 9.5 13.6 15.3 10.1 18.3 12.1 6.3 12.6 20.8 10.7 9.3 9.2 12.0 8.5 9.2 29.1 6.6 11.4 11.3 7.9 17.5 11.6 6.6 15.2 20.8 9.1 10.5 11.8 9.8 8.4 3.0 4.1 4.9 4.1 8.7 8.3 2.3 1.0 3.5 14.7 3.6 1.6 1.2 19.4 1.0 0.9 2.0 1.6 8.7 5.7 0.0 2.2 1.9 0.9 1.6 2.2 1.2 3.6 2.5 6.3 5.3 10.4 3.8 1.3 4.1 3.6 1.1 2.6 0.9 8.2 7.3 1.3 1.5 8.4 13.8 14.9 25.5 1.9 25.1 16.2 2.1 1.2 1.5 8.8 31.0 1.2 8.4 2.6 0.9 6.7 2.8 2.5 3.2 0.6 1.3 3.1 2.2 8.5 0.9 3.8 2.6 4.7 1.8 3.1 5.2 3.0 7.0 2.3 3.4 4.9 2.0 3.0 8.3 6.6 4.9 8.7 4.1 4.1 2.8 2.3 13.7 15.5 21.6 20.1 12.3 6.7 15.3 10.1 10.7 15.2 DNMT3B ENSG00000088305 "DNA methyltransferase 3 beta" Q9UBC3 20 32762385-32809356 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.7;testis: 23.3" "Cell line enhanced" "Detected in many" "BEWO: 55.9;CACO-2: 21.0;HEL: 22.0;K-562: 21.1;NB-4: 18.6;NTERA-2: 75.5" "Cancer enriched" "Detected in all" 25 "testis cancer: 111.7" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001595, HPA001803, CAB069896" Enhanced Supported Nucleoplasm Nucleoplasm "CAB069896: AB_2094115, HPA001595: AB_1847814, HPA001803: " "unprognostic (7.65e-3)" "unprognostic (3.52e-3)" "unprognostic (1.17e-1)" "prognostic unfavourable (5.04e-4)" "unprognostic (3.42e-1)" "unprognostic (7.27e-2)" "unprognostic (4.39e-4)" "unprognostic (4.18e-3)" "unprognostic (8.60e-3)" "unprognostic (8.48e-2)" "unprognostic (6.79e-2)" "unprognostic (4.65e-2)" "prognostic unfavourable (1.87e-7)" "unprognostic (6.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (6.55e-2)" 1.1 0.8 0.9 2.5 0.9 4.7 2.4 4.5 1.4 1.6 2.1 0.7 0.5 0.9 1.3 4.7 1.6 1.1 1.6 1.8 0.8 0.7 2.7 1.2 1.2 1.9 0.9 0.5 1.2 7.5 2.5 1.1 2.8 0.8 1.1 0.8 1.2 3.5 1.6 0.5 5.5 0.8 1.0 0.5 1.3 1.1 23.3 0.8 17.7 2.6 1.7 2.5 2.7 2.2 0.7 1.0 0.0 0.2 0.9 1.3 0.1 0.8 1.1 6.1 1.4 0.1 0.5 55.9 0.7 0.5 0.8 0.8 21.0 0.9 2.2 2.2 0.3 0.5 3.9 0.3 0.6 0.2 3.1 22.0 0.7 4.0 0.2 0.9 2.2 0.5 0.4 1.2 0.2 1.4 21.1 0.6 0.3 3.4 3.3 18.6 75.5 0.7 3.3 1.0 0.5 2.0 0.9 1.9 1.3 1.3 1.9 0.5 1.3 1.2 0.3 1.2 2.8 0.6 0.5 1.3 0.6 0.8 0.6 6.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.7 0.2 0.0 1.0 0.0 1.3 0.0 0.0 0.9 0.1 0.9 0.0 0.1 0.9 0.9 4.5 1.4 0.8 0.7 0.9 0.5 0.8 0.8 DNTT TDT ENSG00000107447 "DNA nucleotidylexotransferase" P04053 10 96304396-96338564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Terminal addition" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 171.0" "Group enriched" "Detected in some" 420 "MOLT-4: 48.7;REH: 168.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "naive B-cell: 1.2;naive CD4 T-cell: 4.5" "Group enriched" "Detected in many" 15 "B-cells: 1.2;T-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036532, HPA044194" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA036532: , HPA044194: AB_10960525" "unprognostic (4.24e-1)" "unprognostic (1.00e-1)" "unprognostic (2.60e-2)" "unprognostic (1.86e-2)" 0.0 0.0 0.1 0.1 0.3 24.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 2.7 0.0 171.0 0.6 0.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 168.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947619 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Enhanced Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA066767: , HPA068706: " "unprognostic (6.35e-2)" "unprognostic (2.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-3)" "unprognostic (3.55e-1)" "unprognostic (2.81e-3)" "unprognostic (8.90e-3)" "unprognostic (3.26e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-2)" "prognostic favourable (5.53e-4)" "unprognostic (3.20e-2)" "unprognostic (1.06e-1)" "prognostic favourable (6.88e-5)" "unprognostic (6.13e-3)" 11.0 20.2 7.9 7.8 13.8 1.4 9.5 7.0 18.6 9.8 8.6 14.9 7.1 8.8 12.4 16.8 10.9 10.8 10.8 12.0 7.6 9.9 17.5 22.0 10.6 10.6 8.1 6.7 13.2 16.9 19.2 8.0 19.5 16.3 12.3 8.0 14.2 15.5 12.8 7.9 11.4 10.9 11.1 5.9 11.6 12.4 22.4 6.0 12.5 11.0 11.9 12.1 10.4 7.3 9.4 14.2 5.6 16.4 9.8 13.7 9.0 5.1 19.1 6.8 10.0 20.1 10.6 9.2 10.7 17.4 13.2 9.8 15.0 8.1 2.8 5.7 15.5 36.4 9.2 13.4 6.8 4.7 8.1 3.5 13.1 10.8 20.3 3.8 6.3 14.6 12.4 14.2 7.8 12.8 8.5 4.5 14.2 25.2 3.1 3.2 8.7 11.9 3.1 9.0 11.1 11.8 7.7 6.2 7.0 14.2 11.7 6.3 20.5 5.0 10.6 11.9 4.3 14.9 8.8 4.3 10.7 2.8 11.2 3.5 9.0 2.3 13.5 5.6 10.2 13.3 9.1 9.4 9.2 11.2 14.2 9.2 12.1 12.3 2.1 9.8 16.4 8.1 13.7 9.0 7.9 13.8 7.0 18.6 7.6 9.9 8.1 6.7 16.3 6.0 DOT1L "DOT1, KIAA1814, KMT4" ENSG00000104885 "DOT1 like histone lysine methyltransferase" Q8TEK3 19 2164149-2232578 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 64.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011875, HPA071217, HPA074977" Approved Enhanced Nucleoplasm Nucleoplasm "HPA011875: , HPA071217: , HPA074977: " "unprognostic (1.41e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-1)" "prognostic favourable (1.69e-4)" "unprognostic (1.08e-1)" "prognostic favourable (6.00e-4)" "unprognostic (2.53e-3)" "unprognostic (2.21e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (5.25e-3)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" 7.3 8.8 7.0 10.7 11.7 20.1 5.1 20.6 11.7 4.5 7.9 9.8 6.0 13.5 6.4 4.9 8.3 5.4 6.9 5.7 7.0 3.6 9.5 8.5 10.0 8.4 11.9 5.3 6.5 10.8 3.6 8.3 11.6 7.1 5.7 4.9 9.5 6.1 7.4 9.8 9.9 13.0 4.2 6.7 10.4 13.3 64.7 9.7 10.5 9.2 7.0 9.1 4.8 5.3 0.7 1.0 3.0 0.9 2.8 1.4 0.6 12.0 6.5 22.1 12.1 1.6 2.4 29.1 6.9 1.5 3.8 3.0 8.3 4.5 14.2 3.3 4.4 10.9 7.3 3.8 1.8 7.2 9.2 13.1 10.6 8.1 2.7 18.6 24.1 2.4 2.9 7.3 3.7 3.1 15.8 14.9 2.9 6.9 14.9 20.6 17.1 11.6 15.4 6.3 9.7 2.1 5.7 14.8 11.4 4.8 14.4 9.1 6.6 14.3 4.4 10.6 9.6 15.6 13.2 13.8 18.0 9.8 10.5 12.9 6.1 0.5 0.7 3.0 0.9 0.3 1.4 0.7 0.8 0.2 0.9 0.7 0.5 0.3 0.3 2.8 0.9 1.0 0.1 0.6 7.0 11.7 20.6 11.7 7.0 3.6 11.9 5.3 7.1 9.7 DPAGT1 "ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT" ENSG00000172269 "Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1" Q9H3H5 11 119096503-119108331 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053878 Approved "HPA053878: " "unprognostic (1.66e-2)" "unprognostic (3.14e-3)" "unprognostic (1.76e-1)" "unprognostic (7.83e-3)" "unprognostic (6.50e-2)" "unprognostic (8.53e-3)" "prognostic unfavourable (2.03e-5)" "unprognostic (2.52e-1)" "unprognostic (3.95e-1)" "unprognostic (9.05e-2)" "unprognostic (2.08e-2)" "unprognostic (7.12e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (1.08e-2)" "unprognostic (2.52e-2)" "unprognostic (4.57e-2)" 13.0 20.0 6.8 9.7 6.7 5.5 10.0 5.2 9.3 13.2 13.1 8.5 13.0 11.0 10.9 12.0 14.5 11.6 11.3 8.3 5.9 5.8 12.5 53.0 10.0 6.9 7.5 3.6 11.6 32.1 18.4 5.8 12.5 7.4 10.6 11.1 8.1 26.3 13.6 8.0 6.9 15.3 10.6 6.4 12.2 11.9 5.4 8.0 7.7 11.8 7.2 12.4 16.1 8.3 10.1 16.4 9.2 14.4 7.6 11.8 8.0 5.5 14.0 4.9 15.1 18.9 11.3 6.7 10.1 10.6 6.8 10.2 13.7 23.5 11.8 16.0 14.4 18.0 13.7 18.4 7.8 6.5 7.5 21.0 4.5 16.7 15.6 13.3 10.5 14.5 15.4 18.5 25.8 15.8 13.0 22.9 15.3 17.6 3.2 8.1 5.6 15.7 5.4 6.7 16.5 17.6 13.1 6.6 6.7 7.4 24.9 4.1 33.5 5.5 8.0 16.9 6.4 7.5 5.3 3.3 8.7 3.8 3.2 17.1 13.1 9.2 14.4 1.4 9.8 13.2 11.8 10.1 7.5 9.7 16.4 7.3 6.0 6.0 1.4 7.6 11.5 15.2 6.7 8.0 6.8 6.7 5.2 9.3 5.9 5.8 7.5 3.6 7.4 8.0 DPH1 "DPH2L, DPH2L1, OVCA1" ENSG00000108963 "Diphthamide biosynthesis 1" Q9BZG8 17 2030110-2043430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069750, HPA073864" Approved Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA069750: , HPA073864: " "unprognostic (5.54e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-1)" "unprognostic (1.86e-2)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "prognostic favourable (1.78e-5)" "unprognostic (2.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (7.30e-2)" "unprognostic (1.41e-1)" 16.6 22.9 17.6 19.0 22.7 10.3 17.0 38.6 26.5 17.8 17.1 17.2 21.1 17.0 22.2 17.0 17.9 29.0 22.6 20.2 14.1 13.1 21.4 32.7 15.7 22.7 17.0 21.6 25.2 29.4 28.4 42.9 17.3 15.4 26.1 13.3 21.3 25.7 23.9 33.3 29.0 17.3 18.9 11.4 17.8 18.4 19.5 19.9 17.5 21.0 25.8 19.0 17.2 16.0 11.3 9.3 0.7 6.8 5.6 12.0 5.5 9.0 15.8 4.3 10.6 13.6 9.9 11.9 11.9 17.9 20.3 13.2 15.1 7.4 17.6 15.4 35.2 7.2 14.5 13.4 11.0 4.6 33.3 4.1 7.4 9.0 12.9 5.1 6.7 14.9 13.7 16.2 13.2 9.1 13.8 7.2 7.9 11.9 9.0 3.3 4.0 16.2 10.4 3.1 13.6 9.0 5.6 8.2 9.5 10.8 12.2 11.9 17.8 4.2 6.3 14.2 6.5 17.4 10.7 7.2 5.0 4.3 13.9 7.0 4.9 0.0 4.6 0.7 9.5 6.8 10.4 11.3 7.8 8.6 9.3 9.5 12.0 8.7 0.3 5.6 4.6 6.7 10.4 5.5 17.6 22.7 38.6 26.5 14.1 13.1 17.0 21.6 15.4 19.9 DPH2 DPH2L2 ENSG00000132768 "DPH2 homolog" Q9BQC3 1 43970000-43973369 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045796 Uncertain Approved Nucleoplasm Nucleoplasm "HPA045796: " "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-3)" "unprognostic (9.13e-3)" "unprognostic (3.83e-2)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.17e-8)" "unprognostic (1.38e-1)" "unprognostic (1.81e-1)" "unprognostic (3.72e-1)" "unprognostic (2.49e-1)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "prognostic favourable (1.37e-4)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (6.37e-2)" 9.6 12.7 13.5 12.4 14.1 7.5 9.8 7.9 18.8 8.3 12.0 12.4 5.9 8.9 9.4 7.5 15.2 10.8 11.5 11.6 11.6 6.3 11.5 21.7 8.5 14.1 13.6 9.3 9.1 21.1 10.4 10.6 8.3 9.7 9.8 11.9 5.8 11.6 9.2 33.4 13.1 9.9 11.2 7.6 13.7 10.6 14.7 12.3 10.8 8.9 14.6 13.5 10.3 7.8 9.0 10.2 0.5 9.2 9.8 10.1 5.8 9.8 11.4 5.1 10.9 3.9 4.1 17.4 5.3 5.7 13.8 11.2 14.5 9.7 16.6 9.0 5.4 11.4 17.2 15.0 7.4 11.4 15.0 17.1 14.2 14.9 10.2 19.7 9.7 6.3 16.7 16.2 9.0 9.5 21.6 9.4 6.8 11.5 17.4 10.9 35.5 13.1 15.0 11.8 27.0 8.6 7.9 17.7 20.5 7.0 17.6 12.8 7.4 13.7 6.2 6.6 15.2 11.7 20.9 23.0 38.1 17.1 5.9 22.0 9.7 0.0 6.6 0.3 6.7 9.2 9.9 9.0 6.8 6.9 10.2 8.8 7.0 10.1 0.5 9.8 4.7 8.5 6.6 5.8 13.5 14.1 7.9 18.8 11.6 6.3 13.6 9.3 9.7 12.3 DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046439, HPA076234" Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA046439: , HPA076234: " "unprognostic (1.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (3.57e-2)" "unprognostic (8.59e-2)" "unprognostic (8.12e-2)" "unprognostic (1.37e-2)" "unprognostic (2.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.88e-1)" "unprognostic (9.00e-2)" 12.6 21.5 11.2 9.1 19.0 7.9 21.4 10.4 11.9 17.3 12.8 11.5 13.2 6.8 20.6 19.0 16.1 19.3 10.0 19.2 11.2 11.9 14.1 18.1 8.5 15.2 11.9 11.4 39.0 28.4 15.5 31.7 9.3 12.3 15.3 13.7 10.8 16.1 12.7 16.8 11.5 9.2 15.4 16.7 13.6 11.5 9.2 11.3 22.2 18.4 15.5 17.7 14.4 14.7 12.1 8.4 3.3 6.2 14.9 16.2 6.7 9.5 8.7 13.0 12.7 16.0 45.7 11.2 8.5 13.8 12.3 10.4 10.4 2.4 16.8 11.2 7.1 6.2 14.4 12.8 18.2 7.0 10.6 8.8 8.4 19.6 25.0 10.7 4.7 30.6 18.7 11.5 37.5 18.4 19.7 5.3 18.6 8.2 13.0 10.5 10.5 13.6 12.1 18.9 9.6 13.9 7.3 15.0 7.3 4.6 12.9 37.3 8.4 6.4 9.3 7.3 10.3 10.6 11.1 6.3 7.3 10.3 10.0 10.1 2.7 3.3 5.1 2.6 11.1 5.5 15.1 12.1 12.3 12.1 8.4 9.6 16.2 14.8 1.9 14.9 6.2 6.2 8.2 6.7 11.2 19.0 10.4 11.9 11.2 11.9 11.9 11.4 12.3 11.3 DPM1 "CDGIE, MPDS" ENSG00000000419 "Dolichyl-phosphate mannosyltransferase subunit 1, catalytic" O60762 20 50934867-50958555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051818 Approved "HPA051818: " "unprognostic (2.21e-2)" "unprognostic (4.94e-2)" "unprognostic (1.16e-1)" "unprognostic (4.24e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavourable (1.94e-6)" "unprognostic (1.10e-1)" "unprognostic (7.49e-2)" "unprognostic (2.53e-2)" "unprognostic (1.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.02e-3)" "unprognostic (4.98e-2)" "unprognostic (2.59e-1)" "unprognostic (3.58e-1)" "unprognostic (2.74e-1)" 32.3 39.7 20.2 23.3 30.0 32.9 29.0 22.5 35.1 31.1 28.1 21.3 28.9 24.0 29.9 32.9 36.0 25.6 24.0 38.7 22.2 21.5 41.7 54.0 24.2 33.0 21.6 17.2 30.8 38.9 21.2 35.1 43.9 31.4 29.8 28.9 22.8 35.9 31.5 44.7 27.1 35.6 24.9 21.1 38.6 30.4 25.6 21.7 36.1 34.5 49.1 36.4 35.3 28.3 20.7 25.0 22.2 19.6 20.3 25.1 15.7 34.6 14.1 21.8 13.0 19.0 21.6 23.9 13.8 15.8 26.7 21.1 63.5 28.2 21.2 30.1 17.8 39.9 17.4 32.7 27.2 10.1 13.9 22.0 18.3 42.7 27.1 34.8 13.2 18.5 48.3 18.5 19.3 20.3 33.1 26.9 26.5 15.3 31.5 36.8 22.3 32.2 17.5 31.9 28.0 26.6 21.1 16.4 17.9 35.6 52.6 46.0 35.8 41.3 16.8 34.3 28.5 20.1 28.3 19.2 24.3 30.4 37.8 23.3 15.5 12.2 16.8 18.6 19.0 19.6 23.0 20.7 21.8 20.3 21.9 19.3 23.7 25.1 22.2 20.3 18.9 25.0 21.0 15.7 20.2 30.0 22.5 35.1 22.2 21.5 21.6 17.2 31.4 21.7 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211566 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Uncertain Uncertain "Nuclear speckles,Intermediate filaments" "Nuclear speckles, Intermediate filaments" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavourable (8.73e-5)" 6.4 9.2 13.8 4.4 13.3 19.6 8.2 20.4 16.4 8.4 6.5 6.8 4.2 3.3 10.5 7.4 6.7 9.2 5.4 5.7 10.7 9.0 9.3 2.5 7.3 5.4 8.1 11.8 14.0 5.9 22.0 11.0 7.1 12.2 7.2 4.6 9.2 6.2 8.8 14.6 14.0 4.8 8.8 11.0 7.0 5.3 11.5 9.2 7.1 8.4 3.6 5.3 7.6 6.4 3.5 3.1 9.8 3.5 4.8 5.1 1.6 6.8 4.5 4.8 5.8 7.0 11.9 3.4 8.6 8.6 9.0 6.2 2.0 3.8 5.1 2.6 14.5 4.9 5.2 5.5 9.2 2.4 5.7 9.2 5.9 2.1 6.3 2.6 4.9 7.0 8.4 9.2 8.8 6.6 11.9 3.4 7.1 4.7 2.0 2.3 5.2 5.4 1.8 8.7 4.4 6.0 4.3 2.7 5.2 7.3 7.6 24.1 5.6 3.4 6.5 5.6 5.7 8.5 5.7 3.5 2.5 3.0 6.6 3.6 20.1 9.8 3.5 6.0 4.6 2.5 4.3 2.7 3.4 3.8 3.1 3.5 5.1 3.7 5.1 4.8 1.8 2.3 2.0 1.6 13.8 13.3 20.4 16.4 10.7 9.0 8.1 11.8 12.2 9.2 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.7;lymphoid tissue: 13.3" "Group enriched" "Detected in some" 12 "Daudi: 40.0;REH: 16.4;U-698: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive B-cell: 2.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: " "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavourable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.7 2.3 6.1 8.9 7.0 3.2 3.9 7.3 8.3 0.8 0.7 1.1 0.5 1.6 2.0 0.5 1.2 1.7 1.0 2.7 5.4 5.9 1.7 6.4 0.5 13.3 3.7 4.2 0.5 2.0 0.0 2.2 0.9 4.6 0.8 0.2 1.4 3.2 0.5 0.5 0.5 2.2 0.5 1.1 9.8 1.0 4.9 0.5 0.5 1.3 0.5 8.1 0.5 0.5 2.3 0.0 0.0 0.0 1.0 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.6 0.0 0.7 0.0 16.4 0.0 0.9 0.0 0.0 1.0 2.7 0.1 0.1 0.9 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.2 0.0 40.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 2.3 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.2 6.1 7.0 7.3 7.1 5.4 5.9 3.7 4.2 4.6 0.5 DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 19.1;esophagus: 19.2" "Cell line enhanced" "Detected in all" "A549: 28.0;CAPAN-2: 46.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA042931: " "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (2.85e-2)" "unprognostic (1.28e-3)" "unprognostic (7.54e-2)" "unprognostic (4.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (1.13e-8)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-2)" 2.9 1.3 0.4 4.8 0.5 1.5 3.2 0.4 0.2 4.8 5.7 4.1 3.0 0.0 19.2 3.2 3.8 1.8 0.5 0.5 1.6 2.8 3.2 3.9 0.7 2.7 4.3 3.8 2.1 1.8 4.6 3.2 10.5 1.3 2.8 11.6 5.5 1.3 1.1 4.9 6.1 8.3 2.7 4.0 4.6 8.8 7.0 14.7 19.1 14.1 3.3 9.0 6.4 12.7 28.0 4.2 6.1 2.4 2.3 9.0 2.7 2.4 3.1 4.2 7.8 46.2 4.0 2.0 2.7 9.6 2.2 13.3 1.9 8.9 4.7 2.3 5.7 6.8 3.2 3.3 5.8 4.1 8.1 7.9 4.3 2.3 6.9 6.0 3.7 6.2 5.0 11.5 6.0 4.2 5.6 3.8 7.1 1.4 10.0 1.6 3.4 4.5 7.7 3.7 7.7 8.8 2.4 17.3 8.2 5.8 11.0 4.5 5.3 4.5 3.7 3.5 8.8 12.4 9.2 13.3 7.6 10.9 5.5 6.0 6.4 7.5 8.4 7.0 6.6 6.9 19.1 3.3 14.1 14.7 9.0 6.4 DTX3 "FLJ34766, RNF154" ENSG00000178498 "Deltex E3 ubiquitin ligase 3" Q8N9I9 12 57604622-57609804 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 54.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 2.0;T-cells: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059654 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA059654: " "unprognostic (2.31e-2)" "unprognostic (8.80e-2)" "unprognostic (2.06e-2)" "unprognostic (3.68e-1)" "unprognostic (3.35e-1)" "unprognostic (2.58e-2)" "unprognostic (6.91e-2)" "prognostic favourable (9.87e-4)" "unprognostic (1.84e-1)" "unprognostic (4.26e-2)" "prognostic favourable (1.44e-4)" "unprognostic (8.62e-2)" "unprognostic (5.44e-3)" "unprognostic (7.99e-2)" "unprognostic (8.81e-2)" "unprognostic (9.51e-2)" "unprognostic (3.48e-2)" 7.2 18.8 22.7 9.0 35.2 3.5 9.4 47.8 53.6 17.6 22.8 23.7 11.0 6.7 29.7 30.6 9.7 31.8 14.1 20.5 23.8 19.8 11.4 2.4 12.2 11.0 18.3 28.4 36.3 12.0 23.9 32.7 16.0 22.5 21.1 10.1 20.4 13.2 29.5 10.9 7.9 9.4 28.7 16.9 11.2 11.2 7.8 21.6 6.8 16.8 5.1 8.8 11.8 13.5 0.3 0.6 0.0 0.0 2.0 5.5 1.8 3.1 8.4 25.0 0.0 0.0 0.0 0.1 5.1 13.3 11.3 11.5 4.3 13.6 4.5 7.9 11.1 5.2 0.0 0.6 8.0 11.3 1.5 2.6 13.0 4.5 19.3 0.0 0.0 9.5 6.3 8.6 0.1 12.6 0.0 15.4 8.6 7.0 13.7 0.1 19.7 0.7 0.0 20.9 0.2 1.0 8.4 18.2 28.8 4.0 1.2 2.4 14.4 6.9 0.0 14.8 5.9 6.8 7.3 25.2 18.9 0.0 9.5 0.0 7.7 0.0 0.0 0.0 5.5 0.0 1.3 0.3 2.1 2.5 0.2 0.3 1.9 3.5 0.0 2.0 0.0 0.6 4.2 1.8 22.7 35.2 47.8 53.6 23.8 19.8 18.3 28.4 22.5 21.6 DTX3L "BBAP, RNF143" ENSG00000163840 "Deltex E3 ubiquitin ligase 3L" Q8TDB6 3 122564238-122575203 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Protein transport, Transport, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 35.3;BJ hTERT+ SV40 Large T+ RasG12V: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010570 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA010570: AB_1847877" "unprognostic (8.15e-2)" "unprognostic (7.36e-3)" "unprognostic (5.04e-2)" "unprognostic (3.74e-3)" "unprognostic (9.51e-2)" "unprognostic (9.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (9.23e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (8.99e-4)" "unprognostic (2.76e-2)" "unprognostic (2.33e-2)" "unprognostic (7.77e-2)" "unprognostic (9.28e-2)" "unprognostic (3.33e-2)" "unprognostic (2.61e-2)" 32.3 13.0 5.9 22.7 8.4 8.1 11.2 2.0 6.8 14.2 18.5 5.9 6.0 14.8 14.0 12.8 17.9 12.0 15.1 21.5 5.0 5.1 17.3 39.2 21.3 18.3 6.4 3.3 21.7 18.5 10.3 13.9 22.2 6.5 20.9 12.1 7.6 13.9 9.8 14.6 6.2 31.8 10.8 9.7 35.2 12.4 4.9 6.9 24.8 23.9 8.0 18.3 17.0 22.1 6.4 6.5 21.9 13.6 7.8 10.2 6.7 11.4 3.5 1.0 3.0 4.7 10.9 3.9 3.0 11.1 35.3 43.7 3.4 11.8 1.3 5.9 4.9 11.6 3.5 4.8 7.8 9.7 1.3 10.0 2.6 3.6 9.3 5.1 7.9 9.4 5.7 5.3 3.0 6.6 1.2 7.2 2.6 3.5 12.4 3.6 0.6 6.5 13.8 8.1 2.2 9.0 7.4 1.5 1.6 6.2 2.8 22.3 3.2 6.5 8.1 4.0 5.7 0.4 3.8 2.6 1.4 6.1 7.0 6.7 4.1 12.5 8.5 8.7 9.3 13.6 10.2 5.9 7.8 10.0 6.5 6.4 7.1 7.6 21.9 7.8 13.5 0.7 7.4 6.7 5.9 8.4 2.0 6.8 5.0 5.1 6.4 3.3 6.5 6.9 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208587 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 42.8" "Cell line enhanced" "Detected in many" "AF22: 13.3;BEWO: 27.0;CACO-2: 14.6;CAPAN-2: 15.5;RT4: 40.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 6.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles Vesicles "HPA056760: , HPA059294: " "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavourable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favourable (5.81e-4)" "unprognostic (2.57e-3)" 7.0 2.2 8.9 7.6 12.8 8.2 7.9 14.0 16.5 8.9 17.7 29.8 1.4 16.7 4.3 2.3 3.7 6.5 9.5 2.1 10.7 10.9 6.5 23.9 17.7 5.2 15.3 8.8 16.3 5.9 1.7 3.3 15.3 24.8 5.6 18.4 7.7 16.0 3.7 1.5 4.2 14.3 3.6 42.8 5.0 12.2 1.9 9.1 0.8 12.4 2.3 6.7 19.8 14.7 3.3 6.1 3.1 1.0 0.1 0.1 0.2 2.0 2.3 13.3 0.2 3.8 0.2 27.0 0.2 1.1 0.1 0.1 14.6 15.5 4.8 0.9 0.3 6.9 4.1 5.0 0.0 0.3 0.2 0.0 2.6 4.7 1.0 0.4 0.9 0.6 8.4 0.0 0.2 0.0 0.0 0.5 0.6 1.1 0.2 0.0 6.8 0.6 1.6 11.7 0.5 1.1 40.5 0.0 0.0 10.3 2.7 0.3 2.0 0.2 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.5 0.1 1.2 1.0 1.5 1.0 0.7 0.1 1.0 0.0 2.2 0.1 0.0 1.4 3.3 0.0 0.0 3.1 0.1 0.5 6.1 0.0 0.2 8.9 12.8 14.0 16.5 10.7 10.9 15.3 8.8 24.8 9.1 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675742-241686991 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.4 17.6 11.6 17.3 15.0 29.1 14.4 14.5 12.4 10.0 13.8 16.5 9.3 12.0 12.4 9.7 20.0 9.7 10.2 9.4 9.0 6.5 15.5 19.5 10.5 21.0 14.0 9.5 9.5 13.6 5.0 8.8 10.4 11.8 11.5 11.7 10.8 9.6 10.0 6.7 17.9 13.0 13.0 9.5 18.8 13.5 11.1 15.1 20.7 9.4 16.1 17.9 11.7 11.9 19.8 21.1 12.0 24.7 15.7 21.8 15.7 25.2 27.9 24.2 30.8 8.0 8.7 25.7 20.7 15.6 27.5 32.5 12.7 30.6 12.2 6.4 16.7 21.3 22.3 25.1 14.8 28.8 26.5 26.2 23.4 24.1 6.6 16.6 21.7 6.1 6.8 26.6 10.8 26.4 29.4 10.3 29.2 26.3 30.6 28.8 23.9 23.5 26.2 35.7 17.0 15.9 14.6 29.3 18.3 13.4 20.7 16.5 18.8 29.7 17.1 40.2 28.9 25.6 38.1 11.6 12.2 34.3 32.2 26.6 46.7 12.0 14.9 9.5 17.4 24.7 16.8 19.2 16.1 18.2 10.5 19.8 16.0 14.7 2.5 15.7 18.8 21.1 21.8 15.7 11.6 15.0 14.5 12.4 9.0 6.5 14.0 9.5 11.8 15.1 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.2 8.0 16.3 11.5 7.8 8.5 14.5 9.1 11.7 9.3 9.8 11.4 9.0 13.8 6.2 16.0 7.0 11.9 8.9 10.9 21.1 5.1 40.8 13.3 6.9 11.7 16.1 15.0 8.6 10.6 12.0 18.5 9.6 15.4 32.0 9.6 10.3 21.1 11.0 17.3 4.8 27.4 9.0 12.7 9.7 13.4 16.9 9.4 20.8 14.3 14.3 13.4 15.0 12.3 12.7 3.8 7.9 7.6 21.8 16.9 19.8 10.1 18.2 13.8 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Cell line enhanced" "Detected in many" "SCLC-21H: 12.1;SH-SY5Y: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported Nucleoplasm Nucleoplasm "HPA028522: , HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favourable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.3 5.9 4.7 4.5 0.7 2.7 1.7 2.5 2.2 0.8 3.3 1.3 10.6 3.2 2.9 1.2 1.9 2.2 4.9 7.2 0.6 5.3 0.8 4.0 0.3 1.8 6.0 1.2 0.8 2.8 0.6 1.3 1.9 0.4 4.2 1.9 0.7 2.0 1.9 0.9 0.1 0.6 5.4 2.1 12.1 13.7 4.2 4.2 0.2 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: " "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.5 7.7 11.5 8.3 5.8 7.9 9.2 13.8 9.0 6.8 3.9 10.1 7.5 25.4 17.1 20.0 15.9 9.2 5.4 7.3 10.9 12.0 4.1 5.1 3.8 2.2 9.2 8.9 6.5 7.8 18.2 14.6 3.8 5.0 13.3 8.6 7.8 7.9 4.5 10.0 12.4 21.1 11.4 11.2 7.9 17.1 15.2 18.0 5.8 7.8 8.0 5.3 7.8 5.6 10.8 10.2 7.4 10.9 6.3 1.0 14.1 10.4 6.3 11.1 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA075041 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA075041: " "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavourable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.4 0.8 4.8 8.6 7.7 0.1 8.1 17.9 7.4 9.6 0.2 1.2 3.7 1.2 9.5 0.7 4.2 6.5 7.9 0.0 2.8 5.4 4.4 0.8 13.7 3.7 3.5 5.4 4.2 12.8 35.2 5.7 10.3 0.7 11.4 0.9 8.1 2.1 6.8 6.4 20.2 2.6 0.0 2.3 0.1 4.9 3.6 7.3 0.3 9.9 0.9 0.9 4.3 15.5 5.9 7.5 6.7 2.9 1.0 4.4 9.2 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Cell line enhanced" "Detected in many" "HHSteC: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028065, HPA056073" Enhanced Enhanced Vesicles Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.9 4.2 5.9 7.2 4.6 2.3 4.7 5.3 5.8 0.6 3.1 5.8 0.3 6.6 4.0 2.9 4.3 4.2 4.4 6.6 4.0 0.8 3.3 16.6 3.5 3.2 4.9 9.3 3.7 12.3 7.5 1.6 6.6 4.8 4.0 3.2 8.6 5.2 1.8 0.7 2.8 2.5 6.5 1.9 0.0 1.5 0.4 2.3 3.3 1.8 3.1 0.5 6.3 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589682-108694846 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 57.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles Vesicles "HPA035066: AB_10601549, HPA049232: " "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favourable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 4.6 9.3 14.1 4.5 25.7 3.1 5.0 14.5 23.7 5.2 4.4 5.8 2.1 2.8 7.4 9.7 3.8 17.4 5.4 10.8 13.2 18.5 10.5 3.9 6.0 8.4 10.3 16.0 10.3 4.9 10.3 57.4 4.5 20.3 9.2 4.5 4.0 3.3 7.0 10.1 3.4 3.6 7.9 9.2 7.0 6.0 29.9 8.0 10.4 12.0 2.8 7.0 5.0 3.5 6.8 1.8 5.2 1.6 11.7 6.5 1.8 6.6 6.0 17.2 10.3 7.6 8.0 5.9 4.2 8.3 7.0 9.5 8.4 4.5 12.0 9.0 4.4 2.5 9.8 3.6 14.8 4.4 4.2 5.5 2.3 5.8 4.6 2.1 3.1 8.3 1.9 6.5 8.1 4.3 5.2 5.9 13.2 6.0 5.3 2.3 10.5 4.3 6.9 14.2 1.1 5.8 3.2 11.7 11.2 7.0 0.7 7.5 10.3 1.9 5.0 6.3 9.6 1.2 3.6 6.8 3.9 23.3 4.8 1.7 7.6 5.2 0.7 1.4 5.0 1.0 6.0 6.8 5.1 6.1 0.6 6.0 4.5 6.0 0.1 11.7 1.6 1.8 6.5 1.8 14.1 25.7 14.5 23.7 13.2 18.5 10.3 16.0 20.3 8.0 E4F1 E4F ENSG00000167967 "E4F transcription factor 1" Q66K89 16 2223566-2235742 "Enzymes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052042, HPA069007, HPA071325, HPA072309" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA052042: , HPA069007: , HPA071325: , HPA072309: " "unprognostic (3.05e-1)" "prognostic favourable (9.13e-4)" "unprognostic (7.31e-2)" "unprognostic (4.57e-3)" "unprognostic (2.89e-1)" "prognostic favourable (1.10e-4)" "unprognostic (9.16e-2)" "unprognostic (4.23e-2)" "unprognostic (3.08e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (8.49e-3)" "prognostic unfavourable (5.50e-4)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (5.12e-1)" "unprognostic (8.93e-3)" 12.4 12.8 18.1 13.8 15.4 21.0 21.0 26.1 18.9 10.8 10.7 11.9 9.3 13.4 14.8 10.4 11.4 10.9 13.5 9.8 14.3 10.7 11.7 12.9 10.0 13.4 16.7 16.4 13.8 17.0 11.6 14.8 12.0 12.8 15.5 5.0 8.7 20.7 13.7 26.7 23.2 14.7 10.3 9.8 18.8 15.9 14.6 17.2 13.3 17.3 9.3 10.6 10.5 13.4 11.5 11.6 15.2 14.2 8.5 14.7 9.3 6.1 11.7 5.0 9.7 2.9 2.6 11.8 8.5 4.0 6.0 4.0 18.8 9.5 9.0 9.3 3.3 8.4 4.1 4.4 1.1 9.7 14.6 6.4 18.9 10.1 5.7 8.1 11.3 4.0 5.0 5.4 2.5 4.0 14.8 6.3 2.2 17.0 10.5 17.2 11.1 10.9 19.6 5.4 15.5 3.7 4.4 12.5 9.2 10.4 13.1 6.0 11.3 11.5 7.1 7.1 9.4 7.0 7.2 12.3 5.9 18.1 3.0 5.7 7.2 7.5 10.7 14.6 14.7 13.1 12.5 11.5 12.0 13.6 11.6 11.5 13.2 11.9 15.2 8.5 14.2 7.0 14.1 9.3 18.1 15.4 26.1 18.9 14.3 10.7 16.7 16.4 12.8 17.2 EEF2K eEF-2K ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206282-22288732 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 3.9;HMC-1: 4.7;NB-4: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm Nucleoplasm "CAB007818: AB_598150, HPA056061: " "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 16.8 5.5 5.3 8.6 3.7 7.6 12.4 17.5 4.8 14.3 10.7 1.3 9.4 5.6 13.2 8.3 6.1 8.2 12.5 9.0 3.2 3.3 3.7 5.5 9.2 6.7 2.4 4.9 6.4 8.1 3.3 3.0 6.4 4.9 12.5 4.6 4.4 12.4 20.5 16.2 37.5 5.1 15.5 1.6 6.1 6.4 4.6 3.1 4.0 4.4 11.5 6.7 13.3 14.2 0.7 2.3 2.2 0.9 1.3 1.6 0.1 0.1 0.0 0.0 0.0 1.0 1.3 1.0 0.0 0.0 0.2 0.0 0.7 0.0 0.9 0.4 0.0 3.9 0.6 0.0 0.0 0.3 0.0 1.6 0.7 2.7 0.0 3.7 4.7 0.0 1.0 0.2 0.3 0.2 0.5 3.3 0.0 0.0 0.2 4.0 0.4 0.0 1.0 2.6 0.7 1.1 0.0 1.0 1.5 0.0 0.0 0.4 0.5 1.2 1.3 2.4 0.9 3.6 0.1 0.7 0.3 1.1 2.7 2.7 0.4 1.5 0.8 0.6 0.5 0.9 0.7 0.4 0.3 0.2 0.2 0.7 0.7 0.3 2.2 1.3 0.5 2.3 1.6 0.1 5.3 3.7 17.5 4.8 3.2 3.3 2.4 4.9 4.9 3.1 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell line enriched" "Detected in many" 12 "A-431: 337.7" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: , CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavourable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 337.7 4.3 1.1 1.5 6.9 4.3 1.1 3.3 4.5 2.0 1.6 0.8 3.7 0.2 0.8 2.8 13.5 0.0 14.9 2.5 0.1 0.2 0.0 1.8 0.2 1.8 0.0 0.0 2.1 13.7 5.2 27.9 0.2 0.0 0.0 4.4 0.2 0.0 0.0 0.3 2.2 0.0 0.6 0.0 2.5 3.6 0.0 1.3 2.8 3.4 0.6 0.3 0.7 1.0 1.9 0.5 14.6 3.1 0.0 0.3 0.1 2.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618963-137870016 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060022 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA060022: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favourable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favourable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" 16.6 18.3 16.4 23.2 22.3 24.9 17.1 23.7 20.4 16.3 20.7 21.6 20.4 17.1 22.0 13.0 17.9 18.5 20.0 12.1 12.8 9.6 12.7 14.9 14.9 25.0 27.8 12.1 21.4 13.6 15.1 16.2 17.9 18.6 16.9 12.4 19.1 16.5 18.0 23.1 17.3 17.9 21.5 12.5 22.1 16.4 30.8 21.5 22.3 18.9 11.0 22.2 19.2 15.7 20.0 19.0 25.0 13.7 13.1 15.6 6.9 11.0 22.1 24.8 22.9 10.5 10.9 20.7 14.6 9.2 10.7 8.7 14.4 13.8 33.8 14.2 11.0 23.7 14.8 15.9 8.5 18.9 10.5 14.3 22.1 9.2 9.2 21.7 17.1 9.8 11.2 12.9 12.6 17.5 21.4 11.7 7.6 25.5 25.4 10.8 24.1 14.7 32.7 21.3 19.5 8.9 20.3 21.9 17.8 27.7 19.5 6.3 21.9 17.5 16.4 12.6 13.1 19.3 13.8 7.5 20.8 27.8 9.3 11.6 13.6 13.6 13.7 16.3 15.6 11.7 10.0 13.3 13.5 13.3 10.4 20.0 13.3 11.8 25.0 13.1 12.0 19.0 11.1 6.9 16.4 22.3 23.7 20.4 12.8 9.6 27.8 12.1 18.6 21.5 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 10.2;NTERA-2: 15.5;U-266/84: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" Nucleoplasm "HPA050550: , HPA060259: " "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 9.4 12.2 13.1 9.6 21.4 7.6 6.3 17.1 17.5 8.0 7.7 12.3 8.4 14.6 15.0 11.7 18.0 7.6 8.1 7.6 12.3 12.4 5.3 4.4 8.5 6.9 12.6 10.6 10.6 13.2 2.2 8.1 6.0 10.3 10.4 4.3 7.2 5.6 9.6 5.2 5.5 10.1 9.6 8.4 9.1 9.8 7.6 14.9 14.6 9.5 4.8 7.2 8.7 7.6 0.3 0.6 0.0 0.7 0.1 1.1 1.3 0.0 3.5 6.3 0.0 2.8 1.5 4.0 2.7 2.2 3.1 2.6 0.0 0.0 0.0 6.2 4.5 0.0 0.0 6.8 1.5 4.1 9.4 0.0 0.0 0.0 0.0 10.2 0.0 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 15.5 0.0 6.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.8 5.2 0.0 0.0 3.0 3.3 2.6 5.6 0.0 9.0 12.2 2.9 3.8 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.2 0.1 0.8 0.6 0.3 0.3 1.1 1.1 0.0 0.1 0.7 0.6 0.2 1.3 13.1 21.4 17.1 16.5 12.3 12.4 12.6 10.6 10.3 14.9 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022244-6059230 "Enzymes, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: " "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavourable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 21.0 38.2 31.7 25.4 32.7 62.8 26.9 23.9 41.1 22.8 34.5 31.0 20.8 26.5 22.6 28.6 28.4 23.4 21.5 40.0 29.9 30.0 32.0 46.3 22.1 23.3 33.3 30.3 23.0 32.4 61.9 25.4 43.9 33.4 26.4 34.9 23.4 46.4 26.3 31.6 28.9 29.9 17.8 35.6 25.4 34.7 16.3 22.6 37.1 29.0 17.4 29.6 22.4 20.1 11.7 7.5 17.4 7.4 10.4 10.6 4.8 41.1 25.9 20.8 31.6 20.0 18.0 27.4 21.2 19.4 19.0 24.1 23.7 27.8 32.2 23.3 23.3 29.1 27.0 19.3 24.5 19.9 41.5 33.2 28.2 35.7 16.4 28.2 30.3 14.5 24.4 17.9 19.3 20.1 53.1 31.2 17.8 41.1 15.4 36.0 26.1 29.3 34.0 21.9 37.8 24.1 20.1 25.9 46.6 40.8 54.5 18.1 41.0 34.6 19.2 10.9 40.7 19.2 22.4 31.7 31.6 32.8 22.0 37.2 31.6 10.6 7.4 17.4 9.5 5.9 6.4 11.7 7.4 10.6 7.5 7.7 8.6 7.7 4.1 10.4 6.5 6.6 8.8 4.8 31.7 32.7 23.9 41.1 29.9 30.0 33.3 30.3 33.4 22.6 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157065 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: " "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 25.5 14.2 15.9 16.3 15.5 36.4 13.9 16.4 19.0 14.7 13.7 9.9 9.3 14.5 17.2 21.5 12.1 12.8 15.4 10.7 13.7 19.2 12.2 11.5 13.7 10.7 14.3 15.0 18.7 11.7 19.2 21.1 18.2 17.3 15.0 12.8 10.2 23.0 17.8 7.1 6.7 15.2 16.2 14.0 15.5 14.3 5.1 12.8 14.1 13.6 8.1 10.6 14.8 15.5 8.8 6.9 27.6 10.8 8.6 9.9 3.3 24.9 12.8 7.9 10.0 8.7 11.9 15.6 13.2 19.0 41.8 40.3 14.6 14.9 13.3 17.2 14.4 14.8 13.6 13.4 18.8 29.3 7.2 14.6 9.8 9.5 8.6 14.0 0.1 9.7 5.3 16.7 12.2 10.3 10.1 13.4 9.4 11.1 17.9 7.2 8.2 9.2 18.1 19.4 6.6 7.8 9.6 8.9 9.4 16.1 11.7 25.4 6.0 4.0 13.4 17.0 18.0 7.2 21.2 9.9 16.3 0.2 8.1 9.5 14.8 17.1 8.2 11.1 8.9 10.6 9.0 8.8 7.5 8.1 6.9 7.0 6.1 7.5 27.6 8.6 10.8 4.7 9.9 3.3 15.9 15.5 16.4 19.0 13.7 19.2 14.3 15.0 17.3 12.8 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.8 3.2 7.1 4.6 13.0 9.1 11.3 7.0 9.0 5.0 7.4 7.2 3.5 37.3 4.2 4.7 4.4 5.1 3.9 7.3 13.1 3.3 4.0 3.3 7.4 8.1 4.9 9.5 3.4 6.3 4.6 10.0 5.3 2.3 13.4 3.8 5.4 4.6 4.0 5.2 3.7 18.1 9.8 6.7 6.2 9.2 5.5 7.5 4.1 10.7 7.0 3.9 2.9 4.2 4.3 4.6 9.7 4.3 25.2 12.6 26.4 6.1 4.5 5.7 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934146-40035591 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 32.9" "Group enriched" "Detected in all" 4 "dendritic cells: 32.9;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol Cytosol "HPA011811: " "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.7 16.5 20.2 19.4 27.3 20.2 36.0 22.4 27.3 16.8 16.3 13.6 17.1 12.2 35.7 17.9 17.8 18.1 19.4 18.2 19.5 20.5 15.4 22.7 22.5 16.6 18.6 14.2 20.1 21.5 20.3 34.7 20.5 17.6 22.0 14.6 17.9 16.7 20.3 20.4 20.7 12.2 24.3 14.6 16.1 16.4 11.5 15.1 17.7 24.1 10.6 15.9 27.0 14.4 5.0 32.9 4.2 9.3 3.8 4.5 2.4 13.8 6.6 11.9 17.9 19.6 33.0 11.3 19.5 22.4 16.0 15.8 9.5 6.0 7.3 10.2 26.5 14.8 15.9 23.6 22.4 34.8 7.9 15.7 12.3 11.4 16.8 9.4 10.9 26.0 16.2 15.2 27.5 22.3 11.6 7.0 31.5 4.6 7.8 13.0 7.3 14.9 9.5 16.5 12.1 19.9 9.4 6.2 9.6 13.9 8.5 12.1 11.9 16.3 23.6 21.4 16.2 10.7 12.6 9.7 17.4 2.3 15.0 13.0 29.8 4.2 5.8 4.0 3.6 6.7 3.1 3.5 4.0 4.1 8.4 5.0 4.5 4.2 1.7 3.8 9.3 32.9 2.7 2.4 20.2 27.3 22.4 27.3 19.5 20.5 18.6 14.2 17.6 15.1 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363397-43368074 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 101.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: " "unprognostic (5.23e-2)" "prognostic unfavourable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavourable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavourable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 21.2 15.6 16.2 15.3 25.3 18.3 24.1 6.8 32.5 16.1 23.6 101.5 11.7 20.7 14.1 13.0 46.6 15.1 17.3 11.5 30.3 18.3 26.6 23.8 22.9 22.7 51.4 14.1 9.3 18.3 16.7 8.4 20.9 45.6 21.6 20.1 8.6 20.6 21.6 6.8 54.0 21.7 20.7 99.5 17.2 22.8 8.4 37.2 7.2 23.9 15.6 21.7 20.4 22.6 30.9 61.1 46.9 54.8 30.5 32.3 48.8 23.5 26.6 5.2 10.2 35.2 33.1 16.1 27.9 35.3 35.7 28.8 23.6 41.5 16.3 21.8 43.8 27.2 18.2 34.4 21.9 20.9 12.3 21.2 18.4 17.0 30.6 18.2 22.6 25.3 39.2 42.2 46.6 35.6 14.6 12.4 40.8 17.4 4.2 15.3 7.6 27.5 9.6 13.7 19.9 45.0 28.8 6.3 6.6 16.5 59.1 23.6 27.7 18.2 29.5 30.3 19.1 36.6 35.4 6.2 6.7 7.8 29.4 18.7 27.2 29.0 54.8 46.9 32.3 50.6 28.6 30.9 30.7 31.4 61.1 25.5 20.1 28.1 38.2 30.5 48.1 42.9 31.4 48.8 16.2 25.3 6.8 32.5 30.3 18.3 51.4 14.1 45.6 37.2 ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044314 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6;liver: 43.1;parathyroid gland: 19.9;placenta: 28.4" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 17.3;HAP1: 12.0;HBF TERT88: 16.8;Hep G2: 12.8;RH-30: 18.2" "Group enriched" "Detected in many" 8 "breast cancer: 11.9;glioma: 25.8;liver cancer: 24.0;melanoma: 14.2;prostate cancer: 9.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "prognostic favourable (6.73e-5)" "unprognostic (4.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-5)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.89e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (6.92e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-12)" "unprognostic (9.98e-4)" "unprognostic (8.86e-2)" "unprognostic (3.41e-1)" "unprognostic (9.47e-2)" 1.4 1.3 10.7 1.7 11.5 0.6 4.7 5.8 12.2 0.6 0.6 8.8 0.0 0.7 0.9 2.5 0.8 0.6 1.1 3.1 6.4 4.8 0.7 43.1 0.7 0.9 7.1 7.1 0.7 2.6 19.9 2.8 28.4 8.0 5.0 0.6 5.9 1.1 0.9 1.3 0.7 0.8 1.1 18.6 0.5 0.6 9.3 4.0 0.0 2.0 0.0 1.3 1.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 11.5 0.0 0.0 0.0 6.5 0.2 0.6 10.1 17.3 0.0 0.0 0.0 0.0 0.6 0.0 12.0 0.0 16.8 0.0 10.3 0.1 0.2 12.8 0.5 0.2 2.7 0.1 0.0 7.8 0.0 0.0 0.6 0.0 0.2 0.0 6.5 0.1 2.1 9.8 9.1 18.2 0.0 0.0 0.1 4.5 5.2 0.0 0.0 4.1 2.1 5.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 10.7 11.5 5.8 10.9 6.4 4.8 7.1 7.1 8.0 4.0 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226328-102229589 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.6" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 8.1;HSkMC: 11.9;NB-4: 9.2;SiHa: 18.5" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 11 "classical monocyte: 9.4;intermediate monocyte: 3.1;myeloid DC: 2.6;non-classical monocyte: 6.6" "Group enriched" "Detected in many" 12 "dendritic cells: 2.6;monocytes: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036236 Enhanced Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavourable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 6.3 1.1 1.2 2.1 2.4 3.6 7.3 0.4 0.9 0.2 0.2 0.0 0.0 0.0 0.9 0.3 0.3 0.3 2.5 2.5 0.6 0.2 0.5 0.2 1.8 0.1 0.7 0.0 0.2 0.2 0.0 1.8 2.4 1.1 0.3 0.2 1.6 3.4 1.7 1.7 24.6 0.3 0.0 0.2 0.8 0.2 6.8 0.0 0.0 0.2 2.8 0.0 0.6 2.6 0.0 2.6 0.5 9.4 0.0 0.0 1.9 2.6 0.2 0.1 6.5 8.2 8.1 2.3 0.1 0.2 0.3 0.4 0.4 2.5 0.0 0.3 0.0 0.0 4.9 0.0 0.4 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.1 11.9 1.4 3.0 0.0 0.0 0.1 2.9 0.7 0.0 0.0 9.2 0.1 0.9 0.0 4.3 0.0 1.6 0.0 0.0 0.3 18.5 0.8 0.6 6.7 2.2 0.0 1.3 0.0 0.3 0.2 0.4 5.7 0.0 2.9 5.3 0.0 0.0 9.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.5 0.0 6.6 0.0 0.0 1.9 1.2 2.4 0.4 0.9 0.6 0.2 0.7 0.0 1.1 0.0 ELOVL4 "CT118, SCA34, STGD2, STGD3" ENSG00000118402 "ELOVL fatty acid elongase 4" Q9GZR5 6 79914812-79947580 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease mutation, Ichthyosis, Mental retardation, Neurodegeneration, Spinocerebellar ataxia, Stargardt disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 92.6;skin 1: 41.9" "Cell line enhanced" "Detected in many" "MOLT-4: 21.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "MAIT T-cell: 19.1" "Lineage enriched" "Detected in single" 191 "T-cells: 19.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.67e-2)" "unprognostic (8.58e-3)" "unprognostic (2.38e-2)" "unprognostic (3.08e-6)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (3.46e-1)" "unprognostic (6.91e-3)" "unprognostic (3.39e-1)" "unprognostic (1.38e-2)" "unprognostic (3.45e-3)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "prognostic unfavourable (6.27e-4)" 1.2 2.6 6.0 1.6 8.8 0.6 4.7 16.0 15.5 2.2 1.4 2.3 0.2 1.1 2.8 1.6 11.0 0.9 2.2 0.9 8.4 10.4 1.9 0.6 0.7 0.9 6.3 4.8 2.3 1.0 10.7 7.6 2.2 19.3 4.7 1.6 15.5 3.0 2.3 0.7 41.9 1.3 3.2 3.5 1.0 1.0 5.8 2.3 92.6 2.0 4.4 2.2 1.8 2.6 0.0 0.0 0.0 0.0 0.0 19.1 0.6 0.0 0.6 7.5 8.3 6.3 6.1 1.1 3.8 4.2 3.3 7.2 1.0 0.0 0.0 0.7 5.2 0.7 9.7 5.4 2.4 0.0 12.6 0.3 1.6 0.0 5.8 2.9 1.2 4.9 2.0 3.3 3.4 5.3 0.0 0.0 6.9 1.3 21.5 0.0 7.2 3.9 0.0 10.8 0.0 0.1 0.0 9.9 2.9 4.1 6.6 1.1 2.6 0.2 0.5 1.5 2.9 2.2 2.9 5.0 10.0 0.0 3.5 0.0 2.2 0.0 0.0 0.0 1.8 0.0 19.1 0.0 2.6 3.1 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.2 0.6 6.0 8.8 16.0 13.5 8.4 10.4 6.3 4.8 19.3 2.3 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB017042: , HPA047752: , HPA054197: " "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavourable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavourable (6.80e-4)" "unprognostic (2.76e-2)" 75.7 48.7 17.9 24.2 22.0 33.9 78.8 13.3 22.1 18.2 13.9 38.3 91.2 9.7 15.7 18.0 10.8 16.5 18.0 14.6 18.3 17.5 13.5 36.8 24.4 33.6 41.1 12.3 13.1 5.7 8.1 11.6 13.6 26.4 45.2 6.7 16.1 9.4 88.4 3.6 11.4 17.3 18.0 46.4 18.5 9.5 34.8 29.1 28.7 17.6 5.6 33.6 16.6 19.4 23.8 18.1 60.7 11.3 8.4 25.3 10.4 25.5 18.7 32.8 59.9 87.1 50.6 14.0 29.9 33.6 24.2 34.0 16.5 29.7 29.1 21.7 31.0 15.2 32.3 27.3 36.3 24.5 22.7 28.7 17.4 23.0 47.9 22.6 21.0 46.7 21.5 24.2 30.4 26.8 35.8 16.9 17.4 2.8 67.2 20.1 17.7 14.3 26.2 22.5 10.1 45.5 15.3 30.6 21.1 24.7 12.9 25.0 29.5 21.2 25.4 26.6 23.6 47.3 39.3 14.3 13.1 22.1 13.8 33.0 18.8 9.0 11.3 40.7 8.8 8.1 14.2 21.6 14.7 10.6 18.1 23.8 7.2 6.7 60.7 8.4 9.6 4.8 25.3 10.4 17.9 22.0 13.3 20.2 18.3 17.5 41.1 12.3 26.4 29.1 ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 4.8;MAIT T-cell: 4.9;memory CD4 T-cell: 2.1;memory CD8 T-cell: 3.2;naive CD8 T-cell: 2.3;NK-cell: 5.6" "Group enriched" "Detected in many" 20 "NK-cells: 5.6;T-cells: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favourable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" 7.6 9.8 7.7 7.9 9.4 3.7 7.9 10.9 12.3 4.0 14.5 8.6 0.9 11.8 3.4 2.7 16.6 2.9 11.1 8.1 6.6 5.9 6.4 43.9 3.3 2.2 7.5 9.4 2.0 2.5 10.6 7.1 2.6 15.7 3.0 14.1 4.3 6.9 3.2 1.4 12.3 10.2 5.7 20.0 1.9 16.9 1.3 7.3 1.1 2.3 7.9 4.0 6.0 5.0 0.1 0.0 0.2 0.1 5.6 4.9 0.8 13.2 7.8 28.8 7.1 19.3 20.3 14.7 9.2 4.5 3.2 7.3 3.8 23.3 1.0 0.8 7.1 12.4 21.8 27.0 7.5 4.5 6.3 15.0 8.5 10.0 12.0 14.5 9.7 17.7 6.2 16.5 7.9 6.4 17.8 30.9 7.2 6.9 3.3 1.5 13.2 4.8 2.2 11.3 3.8 21.0 9.9 5.1 11.0 4.7 31.4 4.0 5.3 0.1 2.3 6.5 7.8 11.0 11.1 1.4 4.8 24.4 10.0 0.0 1.6 0.2 0.1 0.1 4.8 0.0 4.9 0.1 2.1 3.2 0.0 0.1 0.7 2.3 0.2 5.6 0.0 0.0 0.2 0.8 7.7 9.4 10.9 12.3 6.6 5.9 7.5 9.4 15.7 7.3 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844389 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.8;neutrophil: 2.9" "Lineage enriched" "Detected in single" 15 "granulocytes: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036337 Approved "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavourable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favourable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 9.9 5.3 11.4 2.1 15.2 1.1 21.4 7.5 12.4 4.0 7.9 15.0 1.4 10.5 2.8 2.1 5.0 2.4 17.5 1.1 13.8 10.9 15.0 1.2 3.7 2.3 19.0 7.7 0.8 7.6 17.2 3.3 3.1 16.7 20.4 10.8 4.2 3.9 1.5 0.9 23.0 18.9 3.6 26.2 0.9 2.9 1.0 11.7 0.0 15.4 5.0 3.7 5.7 5.0 0.1 0.1 3.8 0.2 0.1 0.1 5.8 11.5 4.3 0.0 0.3 0.0 0.0 10.9 0.0 2.5 1.5 5.1 5.6 12.4 0.0 5.3 0.0 0.6 7.4 4.7 2.2 16.0 3.8 21.0 0.5 1.8 0.1 1.7 9.0 0.1 8.6 0.1 7.5 0.0 3.2 4.2 0.0 10.1 0.1 0.1 1.4 0.0 0.9 1.2 0.7 11.5 11.2 4.7 0.7 6.4 5.1 2.8 8.5 0.3 0.1 1.0 5.3 0.1 4.0 11.0 10.9 0.1 7.8 0.4 0.2 3.8 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 2.9 0.1 0.1 0.1 0.0 5.8 11.4 15.2 7.5 12.4 13.8 10.9 19.0 7.7 16.7 11.7 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Supported Cytosol Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favourable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favourable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 14.8 15.3 18.7 11.5 23.4 6.7 19.4 20.0 27.4 33.4 14.8 21.8 35.2 10.8 27.3 14.4 12.8 18.6 17.5 16.0 17.7 19.0 19.1 22.8 13.6 15.4 17.6 13.6 18.9 12.6 14.3 17.4 12.7 23.3 15.9 18.0 13.9 11.1 36.1 28.8 13.4 12.3 16.0 15.8 16.1 12.1 15.0 15.5 16.0 19.9 13.8 20.3 14.7 12.0 16.2 12.2 11.6 18.2 15.8 20.8 11.0 14.3 15.1 11.5 11.0 17.0 14.9 8.2 7.4 13.4 17.4 15.6 12.5 6.1 27.1 11.7 14.2 9.8 12.6 17.6 20.6 4.9 5.2 18.2 10.0 20.6 15.2 9.8 13.6 15.7 27.2 12.0 18.5 16.3 20.4 16.8 17.8 8.8 20.8 16.7 12.9 5.3 15.8 11.2 10.4 17.4 11.8 6.9 12.0 8.4 7.2 14.1 13.7 11.3 11.4 12.0 15.7 12.4 10.7 7.1 11.4 20.8 11.9 11.0 12.2 11.6 10.1 8.2 19.4 14.4 20.8 12.5 16.6 18.3 11.8 16.2 15.0 17.0 2.8 15.8 18.2 12.2 15.6 11.0 18.7 23.4 20.0 27.4 17.7 19.0 17.6 13.6 23.3 15.5 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975214-69013961 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavourable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 14.9 5.8 3.4 10.1 4.4 3.0 11.9 2.5 4.8 16.8 12.1 4.4 10.2 4.8 23.3 10.4 15.1 11.4 18.1 18.2 3.9 3.6 6.6 5.5 15.8 9.6 4.2 5.0 12.7 7.8 3.9 5.5 15.2 5.1 18.9 5.8 8.7 14.0 24.0 28.0 6.1 7.7 29.4 4.9 10.2 10.1 7.4 2.4 8.3 5.4 14.2 7.3 27.0 9.8 1.7 3.4 5.5 2.2 3.3 9.2 1.8 8.1 2.7 5.4 6.5 7.6 14.9 3.9 11.0 13.5 7.0 9.3 3.7 4.6 0.4 1.7 11.9 2.7 3.7 14.3 8.8 26.3 2.6 8.4 6.2 5.2 8.4 4.7 3.5 12.4 12.2 9.0 11.5 38.4 2.3 5.0 23.4 2.1 0.7 1.5 6.2 1.3 0.3 5.6 3.5 6.0 18.7 0.5 3.0 12.6 1.0 10.0 2.8 6.5 20.3 19.7 6.0 2.2 10.6 2.5 8.3 4.0 7.8 7.3 11.0 5.5 2.2 0.0 3.0 1.9 3.5 1.7 4.8 6.4 3.4 1.2 4.1 4.1 0.3 3.3 0.7 0.6 9.2 1.8 3.4 4.4 2.5 4.8 3.9 3.6 4.2 5.0 5.1 2.4 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41091786-41180079 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favourable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 16.8 14.8 19.1 13.9 15.5 45.3 14.5 33.0 20.6 14.8 16.8 15.6 18.9 11.1 18.1 11.6 16.8 15.7 16.5 10.7 16.6 8.3 11.5 12.2 14.1 12.9 16.9 12.7 20.2 15.7 26.4 14.5 27.7 13.8 13.2 12.2 12.3 15.3 17.9 19.5 18.2 17.4 13.8 12.7 15.9 14.7 20.6 18.6 29.3 16.9 10.9 14.1 18.7 22.5 4.3 4.4 9.8 3.9 5.7 3.9 2.3 15.5 11.2 19.0 11.8 12.1 13.0 17.0 7.5 10.9 11.3 10.8 14.2 5.7 16.2 6.6 14.8 12.5 27.4 10.3 12.5 15.8 18.2 12.2 12.8 11.1 13.7 28.8 13.8 12.7 10.8 16.3 13.6 12.5 12.8 22.3 8.9 5.7 8.3 9.0 13.7 7.8 17.1 8.9 10.1 10.7 20.7 6.1 6.4 26.6 13.6 13.0 9.6 16.8 16.1 11.3 13.7 8.0 10.6 15.3 7.2 25.3 8.3 8.9 10.7 5.0 3.2 3.0 3.7 3.9 3.2 4.3 3.6 3.9 4.4 2.9 3.1 2.6 9.8 5.7 2.1 3.0 2.6 2.3 19.1 15.5 33.0 20.6 16.6 8.3 16.9 12.7 13.8 18.6 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408892 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 104.4" "Cell line enhanced" "Detected in some" "CACO-2: 10.3;HaCaT: 9.6;HBEC3-KT: 7.8;MCF7: 8.5;NTERA-2: 32.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 3.4;naive CD4 T-cell: 6.9;naive CD8 T-cell: 5.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.9" "Not detected" "Not detected" CAB026144 Uncertain 24000000 "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favourable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.4 0.4 0.0 2.0 0.1 0.5 1.2 0.9 0.3 5.7 7.9 0.0 3.3 3.3 0.9 1.4 29.3 1.6 7.9 0.4 0.0 0.0 2.8 10.6 2.9 5.8 0.0 0.0 1.2 2.9 104.4 1.3 5.5 1.1 2.1 0.9 1.3 5.8 3.9 0.3 9.5 12.3 0.4 0.2 0.5 1.8 0.8 0.0 5.1 6.0 16.4 17.2 1.6 11.8 0.0 0.7 0.2 0.1 0.2 6.9 1.6 4.9 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 10.3 4.1 0.0 0.0 0.0 9.6 0.0 7.8 0.0 0.0 0.0 1.0 0.0 0.9 0.0 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 1.0 32.1 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.0 0.0 4.8 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 3.4 0.9 0.4 0.0 6.9 5.1 0.2 0.2 0.0 0.7 0.2 1.6 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 1.1 0.0 EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.6;intestine: 12.6;testis: 24.8" "Cell line enhanced" "Detected in some" "BEWO: 5.1;HDLM-2: 19.2;SCLC-21H: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" HPA027497 Uncertain "Intracellular and membrane" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 0.4 1.1 5.8 1.7 15.6 0.7 1.9 1.3 10.5 0.6 12.6 3.6 0.2 5.8 0.5 6.8 0.8 1.8 2.1 0.4 4.6 7.4 0.5 0.4 0.5 0.6 3.5 5.0 0.4 5.1 1.1 10.8 0.4 6.4 1.4 10.3 1.6 2.4 0.7 0.4 0.6 7.3 1.0 2.3 0.5 5.3 24.8 2.1 0.0 1.0 0.0 0.5 0.6 0.3 0.4 0.3 1.5 0.3 0.8 0.7 0.1 1.5 1.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.6 2.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 19.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.0 0.2 0.7 0.6 0.0 0.0 0.4 0.3 1.7 8.9 0.4 1.1 0.0 0.0 2.8 0.1 0.0 0.0 1.0 0.1 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.4 0.2 0.1 0.7 0.1 0.4 0.4 0.3 0.3 0.1 0.4 0.6 0.7 1.5 0.8 0.3 0.3 0.2 0.1 5.8 15.6 1.3 10.5 4.6 7.4 3.5 5.0 6.4 2.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156087 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 41.9;EFO-21: 40.4;PC-3: 48.0;U-251 MG: 49.2;WM-115: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 115 "plasmacytoid DC: 11.4" "Lineage enriched" "Detected in single" 115 "dendritic cells: 11.4" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 6.7 3.4 1.3 3.1 2.6 0.0 5.2 0.5 2.1 12.1 4.9 1.6 1.9 4.3 7.8 3.8 51.2 4.6 16.7 6.4 1.1 0.8 5.7 8.2 6.6 4.7 2.7 1.3 4.5 10.2 2.2 2.8 8.9 3.4 5.8 2.6 5.4 31.0 2.8 3.4 12.7 13.1 2.7 3.0 2.8 6.8 2.4 1.2 1.2 5.7 21.8 25.5 15.2 18.5 0.0 11.4 0.0 0.0 0.0 0.0 0.0 15.4 31.3 8.7 4.2 0.6 0.7 5.1 9.3 13.3 17.0 10.8 13.0 41.9 0.0 40.4 5.3 6.3 2.0 21.6 5.9 0.0 1.4 0.0 9.1 8.3 11.1 0.0 0.0 1.0 8.1 9.2 20.5 18.1 0.0 0.0 10.7 4.9 0.0 0.0 4.2 48.0 0.0 7.9 0.0 18.0 8.0 0.0 1.3 18.2 4.4 1.2 0.6 0.1 22.3 6.1 16.3 0.4 49.2 0.0 0.1 0.1 4.7 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 1.3 2.6 0.5 2.1 1.1 0.8 2.7 1.3 3.4 1.2 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107524-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.0" "Cell line enriched" "Detected in some" 6 "AF22: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 9.7 1.1 2.3 1.7 4.5 0.2 5.1 1.3 8.7 12.3 5.8 0.6 1.4 2.2 13.9 1.3 6.3 2.6 17.2 10.0 2.2 2.5 1.5 4.4 2.7 3.0 2.5 3.4 4.2 2.8 1.2 3.4 17.5 11.9 39.0 5.9 5.4 3.8 6.8 1.7 1.7 3.5 17.3 2.9 1.2 3.7 1.3 2.0 0.0 16.3 6.0 3.0 11.8 12.2 0.3 0.1 0.5 0.1 0.3 0.2 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 3.7 0.0 0.2 0.0 0.8 0.0 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.3 0.1 0.1 0.0 0.0 2.3 4.5 1.3 8.7 2.2 2.5 2.5 3.4 11.9 2.0 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6" "Cell line enhanced" "Detected in many" "AF22: 35.0;ASC diff: 15.5;CACO-2: 25.6;U-2197: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 3.0;gdT-cell: 3.4;MAIT T-cell: 3.4;memory B-cell: 2.5;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.3;naive B-cell: 1.8;naive CD4 T-cell: 1.9;NK-cell: 6.0;T-reg: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB028368 Enhanced 8400000 "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favourable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.1 1.8 8.1 1.9 18.3 3.5 5.2 14.7 29.6 4.9 5.9 3.1 3.2 1.1 6.5 3.1 5.0 6.6 3.3 16.7 19.9 4.4 5.2 0.9 3.7 2.5 2.4 16.4 11.7 1.2 2.0 1.2 1.7 4.9 5.9 4.7 0.8 3.7 6.7 3.1 12.8 4.1 8.2 2.1 3.3 4.0 11.4 2.6 0.5 9.8 3.7 3.2 4.6 4.9 2.5 0.2 3.0 0.0 6.0 5.0 0.7 1.1 1.0 35.0 0.0 15.5 9.6 0.0 8.3 3.6 7.5 2.8 25.6 0.4 0.0 0.0 11.6 3.0 5.4 0.0 3.2 4.1 3.0 0.0 0.3 0.0 0.4 0.0 0.6 3.8 1.9 2.3 0.0 7.1 0.0 0.0 1.9 4.1 0.1 0.0 2.5 0.7 0.0 3.8 0.0 11.7 1.8 6.2 0.0 2.7 0.5 0.6 1.3 0.0 0.0 0.8 1.4 17.1 0.4 0.0 0.0 0.0 3.1 0.0 1.5 3.0 0.0 0.0 3.4 0.0 3.4 2.5 5.0 3.3 0.0 1.8 1.9 0.3 0.2 6.0 0.0 0.2 2.1 0.7 8.1 18.3 14.7 29.6 19.9 4.4 2.4 16.4 4.9 2.6 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.5" "Cell line enhanced" "Detected in some" "PC-3: 7.0;TIME: 9.4;U-138 MG: 19.7;U-2197: 12.0;U-251 MG: 15.2" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.9 2.7 17.6 1.0 9.0 0.8 0.8 1.9 25.5 5.9 1.2 1.5 1.8 0.9 1.9 0.9 1.1 1.0 0.9 2.7 17.3 6.8 0.9 0.8 1.1 0.9 5.4 13.2 6.2 0.8 0.8 6.5 2.7 10.2 4.2 1.1 2.6 1.2 4.1 0.8 1.2 0.9 1.4 17.7 1.5 1.1 2.2 0.7 0.0 3.0 0.0 0.8 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.3 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.1 1.9 0.0 0.0 0.0 0.0 7.0 0.0 2.2 0.4 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.0 0.0 9.4 19.7 2.5 12.0 15.2 0.0 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.0 1.9 24.7 17.3 6.8 5.4 13.2 10.2 0.7 EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97752460 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;ovary: 13.2;testis: 15.5" "Group enriched" "Detected in some" 6 "HEK 293: 8.0;U-266/70: 24.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA007397: AB_2667821, HPA058047: " "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" 0.8 0.5 8.7 0.5 9.8 0.3 0.8 27.9 9.9 2.2 5.8 1.1 0.3 0.6 2.2 1.0 2.1 4.2 2.1 1.1 15.4 1.3 1.3 0.5 0.5 0.4 1.1 6.8 13.2 1.4 0.7 0.6 0.5 5.7 2.5 1.8 0.2 0.6 1.7 0.4 0.5 1.1 3.2 0.8 0.4 1.7 15.5 2.8 0.0 4.3 0.0 0.5 2.1 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 8.0 0.0 2.0 0.0 0.0 1.9 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.0 2.1 0.0 0.8 24.3 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 9.8 27.9 9.9 15.4 1.3 1.1 6.8 5.7 2.8 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419547 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 110.4" "Group enriched" "Detected in some" 4 "AF22: 8.7;HEK 293: 25.0;RH-30: 23.8;THP-1: 20.3" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" 340000 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 1.3 1.3 6.0 1.7 24.6 1.2 2.2 21.6 8.6 2.4 24.6 0.0 0.1 2.5 2.0 7.5 14.7 1.7 3.1 4.2 13.8 2.9 6.9 1.3 1.5 1.3 2.4 5.8 3.0 1.3 110.4 5.6 1.6 6.7 17.9 3.6 0.4 8.2 1.9 1.3 1.4 6.5 20.2 4.8 4.7 14.9 2.1 4.4 0.0 1.3 0.0 1.3 9.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.5 0.6 4.4 23.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 24.6 21.6 8.6 13.8 2.9 2.4 5.8 6.7 4.4 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563564-22603594 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 9.4;brain: 5.3;lymphoid tissue: 10.3;pancreas: 8.3;testis: 3.5" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 36.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 25.0" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.2 9.4 1.6 0.2 3.1 0.2 0.1 1.8 3.9 0.2 0.2 2.2 0.0 1.7 0.1 0.3 0.2 0.1 0.2 0.2 2.0 2.6 0.1 0.1 0.2 0.2 2.1 4.1 0.1 8.3 0.2 1.7 0.1 5.3 0.2 0.2 1.6 0.8 0.2 0.3 0.4 0.2 0.1 1.3 10.3 0.2 3.5 0.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 36.4 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.8 3.9 2.0 2.6 2.1 4.1 5.3 0.6 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 74.7" "Group enriched" "Detected in some" 4 "HDLM-2: 33.9;HMC-1: 20.1;RPTEC TERT1: 9.2" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Region enhanced" "Detected in all" "cerebellum: 74.7" "Group enriched" "Detected in some" 33 "neutrophil: 15.9;plasmacytoid DC: 15.4" "Group enriched" "Detected in many" 33 "dendritic cells: 15.4;granulocytes: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: " "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 2.0 1.5 9.0 1.8 16.6 1.5 5.5 74.7 23.6 3.6 3.4 3.4 3.1 2.8 4.1 2.0 3.8 2.8 3.3 1.1 9.4 5.3 2.3 2.9 1.0 3.3 2.8 7.0 1.7 1.1 0.6 3.8 0.9 7.1 3.3 1.4 1.9 3.9 5.1 7.4 6.0 1.7 1.7 6.0 3.4 1.3 16.7 6.0 0.0 11.6 2.9 3.3 4.5 2.6 0.0 15.4 15.9 0.0 0.0 0.4 0.1 0.0 0.0 4.7 0.0 0.1 0.0 0.1 3.5 0.0 0.2 0.0 0.0 0.0 0.6 1.0 1.8 0.0 3.1 0.0 0.6 33.9 0.4 2.5 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 0.1 0.1 0.1 1.3 0.0 0.0 0.5 0.1 9.2 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.6 2.0 0.3 4.2 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 15.4 0.0 0.1 9.0 16.6 74.7 19.0 9.4 5.3 2.8 7.0 7.1 6.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 22.8;HUVEC TERT2: 31.1;TIME: 30.7;U-251 MG: 26.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.5;intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" 290000 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: " "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favourable (4.98e-4)" "prognostic unfavourable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.7 2.9 3.4 15.4 5.4 0.9 2.5 1.9 8.2 3.8 23.9 16.2 4.6 21.6 2.5 3.2 1.1 5.4 4.4 5.4 5.6 6.5 3.5 1.1 3.0 5.5 12.7 3.8 17.9 5.4 6.1 5.4 12.0 8.2 3.3 25.0 2.2 6.6 4.0 0.7 1.8 22.6 4.0 12.1 3.3 2.3 2.9 9.3 0.1 8.4 1.0 2.1 5.3 3.3 0.1 0.6 0.3 2.5 0.1 0.1 0.4 16.7 7.1 6.8 10.9 0.6 0.6 0.0 3.9 0.2 11.8 2.5 2.4 6.7 0.2 8.4 1.7 15.8 4.6 22.8 3.1 0.0 1.6 0.0 0.7 0.0 7.1 0.0 1.7 2.3 7.3 21.1 0.1 31.1 0.6 0.0 2.3 2.5 0.3 0.1 1.6 4.6 2.0 7.0 0.3 5.8 1.6 7.4 7.8 6.8 0.2 0.1 0.4 0.2 30.7 4.7 12.4 11.9 26.8 0.0 0.1 0.0 8.8 0.3 0.1 0.3 2.5 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 3.4 5.4 1.9 8.2 5.6 6.5 12.7 3.8 8.2 9.3 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561784-184582409 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 49.3" "Cell line enhanced" "Detected in many" "BEWO: 17.2;HaCaT: 23.6;SK-BR-3: 18.3;T-47d: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.1;myeloid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;monocytes: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced 20000 "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavourable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.4 0.9 4.5 5.0 2.6 0.5 9.0 9.7 5.7 22.7 8.8 2.3 1.7 5.7 10.0 1.9 19.9 3.0 9.7 1.6 4.7 1.8 1.7 1.0 4.7 1.0 3.3 3.7 9.0 49.3 1.1 1.7 6.3 7.2 7.7 9.7 3.8 27.7 3.5 0.7 32.3 5.6 3.5 1.3 1.2 16.0 1.1 4.0 0.2 1.0 15.7 8.4 4.0 13.6 0.0 3.1 0.3 1.1 0.0 0.4 0.4 3.8 1.3 8.9 0.9 2.7 0.2 17.2 0.6 1.1 1.3 0.7 1.2 0.1 0.0 1.7 3.6 23.6 3.2 1.2 0.3 0.1 0.7 0.0 0.2 0.0 0.2 0.0 0.2 0.7 7.7 1.1 0.1 0.0 0.0 0.0 0.6 10.1 0.0 3.8 0.9 1.5 0.9 5.4 0.0 0.0 3.4 1.1 1.3 0.7 18.3 0.8 12.1 0.1 0.0 2.2 3.2 1.1 1.4 0.0 0.0 0.1 0.2 0.0 8.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.1 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.4 4.5 2.6 9.7 5.7 4.7 1.8 3.3 3.7 7.2 4.0 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827521 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 3.6;neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain 1000000 "CAB013537: " "prognostic unfavourable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavourable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavourable (8.84e-4)" 14.0 20.7 1.8 4.2 2.9 2.2 17.1 1.9 3.0 29.1 9.5 2.9 14.6 4.1 28.8 10.3 11.0 13.1 35.0 19.0 3.4 1.1 16.8 29.8 16.5 12.0 2.2 0.9 24.6 11.6 5.6 3.1 35.5 3.2 13.7 5.4 11.6 10.8 14.7 5.1 14.2 7.0 12.4 2.2 50.5 8.6 12.2 2.1 2.3 10.2 13.1 7.0 7.7 21.5 0.0 1.6 7.4 3.6 0.0 0.0 1.2 12.5 11.1 11.1 32.2 7.1 4.6 32.9 4.9 10.7 7.7 10.1 9.1 9.6 1.6 22.4 5.0 13.1 4.8 12.9 4.1 2.0 8.9 0.4 6.4 14.1 4.1 0.2 0.3 5.4 19.5 4.9 11.4 28.7 23.6 0.6 6.2 21.8 0.2 4.9 19.0 16.7 17.0 5.5 2.9 9.8 6.6 0.0 9.6 7.5 3.5 7.3 8.9 2.2 24.1 9.6 15.3 17.7 7.2 0.1 0.2 0.5 1.4 4.1 17.4 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 7.4 0.0 0.2 0.3 0.0 1.2 1.8 2.9 1.9 3.0 3.4 1.1 2.2 0.9 3.2 2.1 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in many" 27 "SK-BR-3: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.8" "Lineage enriched" "Detected in many" 4 "T-cells: 8.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Plasma membrane,Cytosol" 430000 "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: , HPA001060: , HPA001338: , HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavourable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favourable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 5.8 2.4 5.2 10.4 7.0 0.1 20.1 4.2 7.0 19.1 46.5 9.1 55.2 21.6 14.9 18.7 40.9 22.7 26.6 24.8 6.3 3.1 37.5 21.5 17.6 3.7 5.1 5.6 19.3 16.2 27.7 8.1 60.8 7.5 23.6 16.6 15.9 28.7 58.1 8.9 35.3 47.2 10.9 4.5 4.0 17.1 6.5 3.7 2.8 35.7 20.8 22.9 19.7 20.3 1.3 0.3 2.1 0.4 0.9 8.8 2.2 3.1 3.8 4.2 2.7 5.1 3.6 5.7 2.2 3.7 4.9 4.2 2.8 8.6 0.2 4.6 5.1 9.8 0.2 5.1 2.3 0.4 3.2 0.1 3.0 4.5 3.0 0.0 0.0 3.5 4.8 3.0 1.8 2.0 0.4 0.1 3.6 4.8 0.5 0.2 7.6 0.9 0.3 1.7 0.4 5.0 9.8 0.8 0.2 4.2 263.9 1.3 7.4 0.1 0.2 2.5 3.3 3.2 1.4 0.4 0.2 0.2 0.2 0.0 8.2 1.6 0.4 0.8 8.8 0.3 0.7 0.9 0.5 2.5 0.3 1.3 1.0 2.5 2.1 0.9 0.2 0.2 0.4 2.2 5.2 7.0 4.2 7.0 6.3 3.1 5.1 5.6 7.5 3.7 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 31.1;MCF7: 20.3;RT4: 24.3;SK-BR-3: 28.6;SK-MEL-30: 38.1;T-47d: 31.7;WM-115: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.3" "Low region specificity" "Detected in many" "CAB025331, HPA045396" Uncertain Approved "Plasma membrane,Actin filaments" "Secreted - unknown location" 420000 "Actin filaments" "Plasma membrane" "CAB025331: , HPA045396: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 1.1 1.4 11.6 12.6 16.5 0.6 26.8 2.0 16.7 6.8 40.5 40.3 12.0 37.7 2.8 7.5 29.4 5.7 22.9 3.4 18.6 9.0 16.5 33.9 13.4 0.5 23.5 9.3 0.9 21.5 11.4 1.0 15.4 14.9 16.8 29.7 5.5 36.8 22.3 1.1 30.7 41.3 3.2 27.4 0.5 32.9 1.2 23.8 0.0 4.5 7.4 8.5 11.8 14.4 0.9 0.7 5.3 0.6 1.2 1.2 0.2 10.1 0.6 0.8 0.3 0.0 0.0 16.5 0.8 1.9 1.1 1.1 5.5 18.3 0.0 0.2 0.2 8.6 1.2 1.9 0.6 0.2 0.8 0.0 0.3 31.1 0.0 0.0 0.1 0.4 2.5 0.2 0.0 0.0 0.7 0.3 0.1 20.3 0.1 0.3 2.8 0.4 0.1 1.9 0.5 2.1 24.3 0.9 0.3 0.7 28.6 38.1 31.7 0.1 0.0 0.1 1.1 0.6 0.1 0.3 0.1 0.1 0.1 0.0 40.5 5.3 0.4 0.8 0.9 0.4 0.4 0.4 0.7 0.3 0.3 0.9 0.6 1.2 3.3 1.2 0.6 0.7 0.8 0.2 11.6 16.5 2.0 16.7 18.6 9.0 23.5 9.3 14.9 23.8 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.5" "Cell line enhanced" "Detected in some" "AF22: 9.4;EFO-21: 7.0;HEK 293: 5.2;RPTEC TERT1: 7.7;SCLC-21H: 4.3;T-47d: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 4.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced 140000 "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 1.6 1.9 15.1 1.2 15.0 1.0 13.4 18.6 14.1 7.8 1.1 7.6 8.8 1.1 1.5 1.2 1.3 24.5 1.2 7.0 14.3 6.5 11.9 1.1 2.9 1.2 7.8 10.7 1.3 2.4 10.8 5.1 1.3 8.8 1.7 1.1 2.0 9.7 18.1 3.8 1.8 1.2 1.1 7.3 1.2 1.5 7.6 12.0 0.0 4.5 1.1 1.2 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.4 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 7.0 1.0 0.4 0.2 0.0 0.0 0.1 5.2 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.7 0.4 4.3 0.2 0.0 0.1 0.1 6.9 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 18.6 14.1 14.3 6.5 7.8 10.7 8.8 12.0 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 40.4;RPMI-8226: 18.1;U-266/70: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.7 0.9 2.3 2.2 1.8 4.4 1.9 4.2 1.3 1.1 1.2 1.2 2.8 1.3 1.4 1.4 1.2 1.8 3.2 0.8 1.0 2.6 0.9 1.8 13.5 1.2 0.9 2.0 5.1 3.6 11.5 2.4 1.8 40.4 1.1 1.5 1.8 0.5 0.3 1.6 1.9 1.9 18.1 1.1 2.9 3.2 1.9 1.8 3.0 4.4 1.6 2.6 2.3 1.1 2.6 2.5 1.1 38.1 10.0 2.2 2.1 1.3 1.8 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690326-23713500 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.5;stomach 1: 30.0" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.6" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 0.7" "Low region specificity" "Detected in all" HPA076875 Approved "Intracellular and membrane" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.3 0.1 8.1 0.2 0.0 0.1 0.1 0.2 11.4 17.3 0.2 0.1 7.0 1.1 0.1 0.9 0.1 64.5 0.1 0.1 0.0 0.2 0.1 1.0 0.5 0.1 0.1 0.1 0.5 0.0 0.8 0.1 0.1 2.6 12.6 0.2 14.0 0.1 0.1 0.1 11.8 0.9 0.1 0.1 30.0 0.1 0.1 0.2 0.1 2.2 7.6 6.3 3.9 0.9 0.6 3.6 0.4 1.5 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 12.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 3.6 0.4 0.5 0.3 0.3 0.2 0.3 0.3 0.3 0.1 0.9 0.3 0.4 2.1 1.5 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA010712: , HPA029407: " "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favourable (1.75e-4)" 15.7 17.7 15.2 41.1 19.4 13.7 16.9 19.7 22.2 12.9 33.2 16.4 14.6 27.2 16.6 24.1 14.7 13.1 27.3 10.4 15.6 23.9 22.0 30.2 19.6 18.5 17.2 15.8 17.2 14.9 15.8 30.6 13.4 18.9 13.8 19.5 15.9 16.7 14.7 8.2 17.8 24.5 10.0 17.1 18.3 53.7 22.3 17.5 33.4 17.6 8.2 16.5 14.2 18.6 16.2 10.7 28.1 17.6 14.0 15.7 13.4 6.7 14.0 15.5 14.3 11.2 11.4 11.6 8.0 6.0 8.3 8.5 10.8 17.0 20.0 7.2 5.2 5.1 13.6 3.8 14.9 16.6 11.0 16.5 6.1 9.2 10.7 15.8 15.2 7.4 3.7 11.1 9.5 10.2 19.8 8.5 10.9 4.6 17.2 32.2 30.0 9.1 15.6 13.8 16.1 13.7 9.1 5.0 8.8 8.7 7.5 12.5 11.8 15.3 8.8 6.6 10.6 8.9 12.0 6.2 7.7 21.5 8.4 10.3 11.0 28.1 11.7 12.1 12.9 17.5 12.7 16.2 14.1 11.9 10.7 13.0 15.7 15.5 11.5 14.0 17.6 9.7 15.3 13.4 15.2 19.4 19.7 22.2 15.6 23.9 17.2 15.8 18.9 17.5 ETNK2 "EKI2, FLJ10761" ENSG00000143845 "Ethanolamine kinase 2" Q9NVF9 1 204131062-204152003 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 65.9;liver: 80.5;testis: 45.0" "Cell line enhanced" "Detected in many" "hTCEpi: 26.4;MCF7: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 4.8;MAIT T-cell: 4.6;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.9;naive CD4 T-cell: 2.9;naive CD8 T-cell: 3.6;NK-cell: 1.5" "Group enriched" "Detected in many" 11 "NK-cells: 1.5;T-cells: 4.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 8 "basal ganglia: 24.7" HPA057167 Enhanced "HPA057167: " "unprognostic (1.64e-1)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (7.81e-2)" "prognostic unfavourable (4.11e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-3)" "unprognostic (4.28e-2)" "unprognostic (6.54e-2)" "unprognostic (4.35e-2)" "prognostic favourable (6.50e-4)" "unprognostic (5.50e-3)" "unprognostic (4.69e-2)" "unprognostic (2.00e-2)" "unprognostic (1.20e-1)" 3.3 2.3 4.0 0.8 4.7 0.9 6.3 0.9 4.0 5.1 1.6 1.9 6.5 0.8 3.1 11.0 8.3 4.9 1.9 2.6 2.6 2.5 65.9 80.5 1.2 2.0 2.7 1.9 13.1 4.3 6.2 8.8 2.3 2.7 3.8 0.9 4.8 7.6 7.8 0.6 5.1 0.8 2.4 1.5 2.4 1.1 45.0 1.9 1.1 4.0 3.9 12.9 3.8 6.2 0.2 0.0 0.2 0.2 1.5 4.8 1.0 5.2 1.8 5.3 10.1 2.0 0.6 5.3 5.4 12.0 7.5 3.3 9.0 2.6 0.2 9.1 1.3 4.7 9.3 7.6 5.2 0.2 8.4 0.1 1.0 13.8 8.0 0.2 0.3 2.7 26.4 1.6 0.3 5.4 0.7 0.2 0.9 25.5 1.5 0.1 11.1 4.0 0.4 6.3 0.2 6.5 2.0 1.4 7.6 3.4 16.1 2.5 15.6 0.3 0.3 2.1 11.7 0.4 3.9 0.2 0.1 0.2 0.1 0.2 3.0 0.1 0.2 0.0 4.8 0.0 4.6 0.0 1.3 2.9 0.0 0.2 2.9 3.6 0.2 1.5 0.1 0.0 0.7 1.0 4.0 4.7 0.9 4.0 2.6 2.5 2.7 1.9 2.7 1.9 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111853 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 55.1;fHDF/TERT166: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain 9600000 "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavourable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavourable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavourable (4.64e-4)" "unprognostic (1.85e-1)" 13.8 11.9 5.8 20.5 4.6 2.1 16.5 7.3 7.4 13.3 17.1 4.1 8.7 23.2 11.5 12.5 11.2 8.8 19.3 14.4 4.6 3.1 8.8 66.4 19.9 8.3 3.0 6.8 10.4 17.9 7.1 6.4 15.6 4.8 9.8 16.0 13.2 9.8 13.3 4.2 12.3 32.0 16.8 4.3 20.1 11.5 5.0 2.7 8.7 12.0 10.3 7.2 11.0 18.5 0.8 1.7 1.2 4.5 0.7 2.4 1.0 17.2 5.0 7.5 2.9 13.6 11.0 3.4 32.3 55.1 23.8 21.9 5.1 1.7 0.3 14.5 55.7 10.9 3.3 18.9 33.5 6.5 5.6 0.6 4.7 4.1 6.4 0.0 1.2 6.9 5.1 28.9 26.6 14.6 0.4 4.8 11.0 1.4 0.8 0.0 2.4 6.4 0.0 2.8 0.5 9.4 6.3 2.3 2.2 4.9 2.3 4.8 3.2 0.2 19.4 20.1 18.4 18.4 9.5 2.7 2.7 1.6 18.6 0.0 5.3 0.3 4.4 0.2 0.2 4.5 1.3 0.8 0.5 0.6 1.0 0.1 0.5 0.9 1.2 0.7 2.2 1.7 2.4 1.0 5.8 4.6 7.3 7.4 4.6 3.1 3.0 6.8 4.8 2.7 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095549-44245429 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" 20000000 "Golgi apparatus" "HPA078409: " "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavourable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavourable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 24.5 19.5 11.6 17.2 18.5 6.6 25.8 14.5 23.0 26.8 25.0 15.5 17.5 17.6 37.1 25.5 16.7 26.0 23.4 22.7 11.7 13.0 19.2 36.3 22.3 16.8 11.8 12.3 29.3 21.8 25.7 17.3 58.0 16.2 23.7 20.6 22.9 24.7 22.8 16.9 20.2 34.0 35.0 12.2 18.7 19.3 20.0 11.4 16.2 24.7 16.7 13.0 20.2 23.2 6.7 14.9 13.0 12.0 17.8 17.6 9.8 12.9 17.9 9.7 30.2 44.8 33.0 13.4 40.2 50.3 23.8 32.4 12.7 8.9 8.9 18.3 47.0 20.6 10.4 28.5 28.8 17.9 14.3 8.2 9.4 9.7 17.7 8.2 17.8 25.6 18.9 14.4 22.5 33.8 11.0 16.2 17.3 9.9 5.7 5.0 10.4 12.8 7.2 27.8 4.5 13.7 12.3 7.0 7.8 25.4 10.4 6.7 17.3 8.8 30.5 32.2 21.1 31.5 25.7 7.3 9.5 6.5 21.2 6.4 34.3 9.3 11.9 13.0 15.6 12.0 17.6 6.4 12.5 14.4 14.9 6.7 11.9 11.7 2.6 17.8 8.5 5.1 9.6 9.8 11.6 18.5 14.5 23.0 11.7 13.0 11.8 12.3 16.2 11.4 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.1;heart muscle: 6.0;skeletal muscle: 20.5" "Cell line enriched" "Detected in some" 10 "WM-115: 57.4" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA037749 Approved "Intracellular and membrane" 68000 "HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.6 2.1 15.3 0.6 9.5 0.5 2.0 1.1 21.1 1.3 0.6 1.4 0.0 0.7 2.5 0.7 1.5 1.7 1.2 6.0 12.7 3.7 0.7 0.5 0.7 0.8 3.7 7.9 2.3 1.0 0.5 0.5 1.0 2.9 1.2 0.6 2.7 0.8 0.9 20.5 1.6 0.7 2.9 2.7 2.2 0.6 1.0 0.8 0.0 0.9 3.2 0.6 0.9 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 57.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.1 15.3 9.5 1.1 21.1 12.7 3.7 3.7 7.9 2.9 0.8 EXTL2 ENSG00000162694 "Exostosin like glycosyltransferase 2" Q9UBQ6 1 100872372-100895998 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020716, HPA068921" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" 83000000 Nucleoplasm Cytosol "CAB020716: , HPA068921: " "unprognostic (3.14e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-2)" "unprognostic (8.20e-2)" "unprognostic (9.07e-3)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (6.84e-2)" "unprognostic (7.83e-2)" "unprognostic (1.24e-2)" "unprognostic (4.34e-2)" 7.5 23.0 9.8 4.1 19.9 1.7 10.4 14.7 22.8 13.4 8.7 8.1 9.9 4.5 16.7 13.1 6.0 10.1 10.3 8.2 9.5 13.3 11.2 10.0 7.6 3.4 14.0 12.0 18.8 7.7 17.5 18.7 21.8 20.1 12.3 7.1 8.6 6.0 11.4 5.3 5.9 4.6 15.4 11.4 5.4 6.2 9.7 16.3 6.4 9.3 5.0 3.4 9.0 6.2 2.1 7.4 3.3 1.1 5.3 5.6 1.9 5.1 2.7 19.8 20.7 22.0 16.2 12.6 8.9 14.6 7.0 15.7 2.5 3.9 5.7 8.6 8.1 5.0 7.2 7.6 14.2 11.6 5.0 7.0 9.6 7.1 7.2 10.9 3.7 19.2 2.7 14.0 2.7 25.5 8.8 0.7 17.6 2.6 5.7 6.0 24.9 6.0 4.2 20.4 4.7 7.5 3.9 8.2 23.3 6.8 1.7 15.9 4.3 4.9 10.7 17.5 10.3 11.2 9.3 6.1 5.4 3.5 27.9 11.3 5.7 3.3 0.8 0.0 5.6 1.1 2.8 1.9 1.9 3.7 2.5 2.1 2.1 4.8 0.2 5.3 0.9 7.4 0.0 1.9 9.8 19.9 14.7 22.8 9.5 13.3 14.0 12.0 20.1 16.3 EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavourable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favourable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" 12.1 19.0 15.4 7.9 19.5 4.0 11.6 14.8 26.9 11.3 10.5 16.2 8.8 6.3 15.0 7.9 14.0 13.7 9.6 34.6 15.4 13.4 8.5 6.7 10.1 5.9 11.6 18.1 12.2 13.0 26.1 13.8 15.7 12.9 10.2 6.5 15.2 8.8 14.8 20.7 13.5 6.8 19.8 11.7 9.3 9.6 14.3 10.8 5.4 9.2 8.7 5.9 12.2 9.5 0.8 2.4 10.0 2.3 1.0 3.6 1.5 19.0 14.4 32.2 16.5 8.8 9.1 7.1 14.4 14.6 9.2 7.7 12.2 6.9 5.1 20.9 17.5 12.9 14.8 23.7 9.9 3.7 8.2 7.3 7.2 6.2 5.1 3.5 20.8 10.2 16.1 7.0 6.4 19.6 6.7 6.7 7.2 3.6 6.4 2.3 21.8 5.9 7.7 13.8 3.0 15.7 12.4 6.9 12.0 6.1 3.8 8.3 3.7 4.4 14.9 12.0 28.4 11.1 12.2 3.6 7.2 5.8 10.1 4.4 10.7 4.0 2.0 3.3 3.6 2.3 2.1 0.6 1.3 1.9 2.4 0.8 1.1 0.9 10.0 1.0 2.3 2.3 0.8 1.5 15.4 19.5 14.8 26.9 15.4 13.4 11.6 18.1 12.9 10.8 EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm Nucleoplasm "HPA005478: AB_1848340, HPA077684: " "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" 21.7 10.4 15.0 10.1 25.0 9.9 18.7 39.6 26.1 18.4 15.1 21.4 10.0 9.7 29.8 21.2 10.6 18.8 9.7 17.2 19.0 11.2 13.6 5.3 12.6 14.0 13.7 22.0 38.2 8.1 20.0 19.1 9.3 25.6 13.1 12.1 21.5 10.7 19.3 25.4 16.0 14.0 16.4 19.9 16.0 10.6 8.6 16.7 11.9 15.0 7.5 14.9 16.0 15.9 6.2 6.0 18.8 5.4 4.8 8.3 2.3 5.4 5.8 7.9 5.4 31.7 19.2 6.7 8.8 8.1 7.3 7.5 2.7 6.8 8.3 5.5 9.3 12.4 5.1 5.9 10.6 9.2 9.2 2.8 10.7 3.3 10.9 6.2 6.9 10.9 10.7 5.5 13.4 5.9 7.5 11.7 6.4 2.3 10.0 7.9 2.1 3.0 6.6 8.0 8.8 7.6 5.8 5.4 4.3 4.9 2.4 5.8 8.4 4.0 6.1 7.9 3.3 9.2 5.5 12.3 6.2 4.9 5.6 6.4 4.0 10.2 5.2 6.9 5.9 5.4 8.3 5.7 5.2 6.0 1.9 6.2 7.7 5.7 18.8 4.8 3.3 6.0 5.7 2.3 15.0 25.0 39.6 26.1 19.0 11.2 13.7 22.0 25.6 16.7 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.5;lymphoid tissue: 44.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009589 Enhanced Supported Nucleoplasm Nucleoplasm "CAB009589: " "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavourable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavourable (8.18e-12)" "prognostic favourable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 2.0 1.7 1.8 10.6 1.6 25.5 1.4 4.9 2.7 2.6 4.8 1.1 0.1 3.8 1.7 2.8 11.0 0.9 3.0 0.9 0.8 0.6 1.7 3.3 2.3 12.6 1.3 0.3 2.2 3.8 0.6 1.7 3.4 1.4 1.4 5.1 1.8 3.2 1.6 3.7 6.4 4.8 1.5 1.2 5.8 2.7 19.6 1.3 44.1 0.9 5.5 12.4 2.6 3.5 1.5 4.7 1.3 3.9 8.5 10.3 1.7 16.9 7.9 27.1 18.0 0.8 1.4 14.8 13.2 5.3 10.9 11.0 11.9 19.6 29.9 6.4 4.9 10.4 13.9 4.5 13.9 42.8 13.9 12.7 9.8 9.2 2.2 28.4 10.5 1.2 2.6 8.1 4.3 6.4 27.1 19.9 9.7 19.2 55.1 23.7 21.5 10.7 34.1 15.2 18.5 5.0 8.1 25.9 16.5 16.6 12.6 4.3 9.2 12.2 3.9 11.6 5.4 23.1 23.6 17.9 19.4 30.1 10.6 19.4 22.7 0.5 2.2 1.3 1.7 1.5 1.3 1.5 3.4 2.9 4.7 0.8 1.9 1.2 0.2 8.5 3.9 1.0 10.3 1.7 1.8 1.6 4.9 2.7 0.8 0.6 1.3 0.3 1.4 1.3 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144085-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 110.1" "Cell line enhanced" "Detected in some" "AF22: 15.3;LHCN-M2: 5.7;RH-30: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 27.6;myeloid DC: 33.7" "Group enriched" "Detected in many" 5 "dendritic cells: 33.7;monocytes: 27.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001804, CAB002155" Enhanced "Secreted to blood" 1400000000 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 56.6 19.4 2.2 11.4 6.5 3.1 57.9 2.2 1.8 13.3 21.8 2.6 2.5 2.2 4.7 35.6 13.4 16.8 12.6 55.4 2.0 2.2 17.5 1.3 14.5 52.7 5.8 1.4 10.2 8.9 5.3 9.3 110.1 7.5 16.4 15.1 11.6 11.5 3.3 18.5 10.4 10.6 20.1 5.0 5.1 11.5 16.7 2.5 2.7 22.4 8.3 6.1 23.7 6.5 0.0 33.7 6.6 27.6 0.0 0.1 63.5 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 28.9 0.5 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 27.6 0.2 0.1 4.9 0.1 0.0 0.0 0.0 33.7 0.0 0.0 0.0 6.6 0.0 0.1 2.4 0.0 63.5 2.2 6.5 2.2 1.8 2.0 2.2 5.8 1.4 7.5 2.5 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C, golgi associated secretory pathway kinase" Q8IXL6 7 192969-260745 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 80.6" "Cell line enhanced" "Detected in many" "HSkMC: 52.0;U-87 MG: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" 160000000 "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavourable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavourable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 27.5 10.2 10.8 19.3 16.6 3.3 25.6 7.4 14.9 8.3 20.1 13.5 15.1 12.9 9.5 6.9 11.1 9.7 15.0 15.0 8.8 7.2 31.8 31.6 12.7 5.1 16.9 5.6 11.8 14.8 2.6 9.2 7.2 15.8 15.0 4.6 8.8 80.6 11.8 20.4 6.8 16.5 17.0 17.0 6.9 20.0 5.9 14.8 0.4 9.6 8.4 4.4 20.5 17.5 0.0 0.6 0.0 1.6 0.2 0.0 0.0 13.8 6.7 0.2 9.6 12.3 20.4 0.0 12.3 20.9 6.7 5.4 0.8 8.5 0.0 6.8 18.4 12.0 1.0 0.6 1.7 2.9 0.6 0.0 3.2 3.7 9.3 0.0 0.9 52.0 1.5 0.2 0.7 4.6 0.0 0.1 1.7 1.8 0.0 0.7 6.5 0.4 1.5 0.4 0.0 5.0 0.0 3.2 0.1 12.8 0.0 1.9 9.1 6.3 12.9 8.4 4.2 7.1 3.7 0.0 0.0 0.0 32.0 0.8 23.8 0.0 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.8 16.6 7.4 14.9 8.8 7.2 16.9 5.6 15.8 14.8 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "Fanconi anemia complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 62.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavourable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favourable (7.80e-5)" 6.3 29.2 16.0 11.2 22.9 10.6 16.2 7.1 18.1 11.6 9.6 30.7 7.9 9.2 16.6 15.7 8.6 11.7 9.8 10.2 17.0 23.5 7.1 16.7 7.7 10.9 25.0 15.2 21.3 10.8 16.8 62.5 10.0 33.5 11.6 12.4 13.7 14.8 9.1 6.5 14.4 10.1 11.3 23.4 12.0 10.5 14.7 28.2 8.6 14.2 6.9 12.0 10.1 12.7 10.8 7.1 5.6 6.9 8.8 5.5 2.7 18.4 13.5 27.6 13.5 4.9 6.5 14.7 13.6 8.5 13.5 17.6 11.9 23.3 12.8 17.7 4.4 10.8 15.3 10.3 22.6 30.0 24.2 21.0 19.0 16.1 5.3 20.2 11.6 4.8 4.9 9.8 3.9 10.5 19.5 11.7 9.1 9.4 7.1 25.1 29.8 2.8 13.5 20.9 10.0 11.8 18.3 31.3 15.7 19.4 8.0 12.7 7.3 13.6 6.2 12.1 18.2 8.8 14.9 12.1 7.6 7.5 25.7 13.7 18.3 2.7 3.7 5.6 4.9 6.9 3.8 10.8 4.1 5.4 7.1 10.0 1.4 3.1 1.1 8.8 4.9 6.5 5.5 2.7 16.0 22.9 7.1 18.1 17.0 23.5 25.0 15.2 33.5 28.2 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078333-82098332 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 147.6" "Cell line enhanced" "Detected in many" "SK-BR-3: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" 1600000 "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavourable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavourable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 147.6 7.8 8.2 14.2 11.5 11.1 57.5 19.1 23.0 6.6 27.7 17.0 14.1 8.2 4.7 14.2 17.1 4.3 19.4 6.3 7.9 6.7 3.7 30.8 26.8 9.8 7.3 11.5 6.4 10.4 6.7 15.3 8.4 21.7 28.8 3.4 7.6 16.9 10.8 7.5 17.2 6.5 4.6 8.4 5.1 11.9 6.6 8.8 1.9 5.1 10.7 5.4 8.0 6.6 0.5 1.4 0.0 0.8 0.2 1.9 0.8 23.1 24.3 11.3 7.8 18.3 12.4 24.2 4.6 6.0 4.9 9.0 25.4 15.8 7.7 3.8 3.5 19.4 10.9 21.3 0.9 3.6 47.4 16.0 18.2 33.9 5.2 8.6 2.4 11.9 5.6 12.5 2.9 5.5 24.1 6.9 1.7 40.1 9.4 13.7 21.9 14.2 8.3 6.4 15.3 5.5 29.7 28.1 15.6 6.8 152.8 12.4 27.2 16.5 9.6 7.2 14.8 5.9 11.0 9.3 2.0 8.0 4.3 9.4 10.6 0.0 0.8 0.0 1.2 0.5 0.7 0.5 1.9 1.4 1.4 0.2 0.7 0.6 0.0 0.2 0.4 1.1 0.6 0.8 8.2 11.5 19.1 23.0 7.9 6.7 7.3 11.5 21.7 8.8 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Approved "Nuclear speckles,Mitochondria" Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavourable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favourable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 13.8 16.8 18.8 15.7 19.0 6.4 10.2 19.0 26.4 18.0 20.6 13.4 20.3 21.2 12.4 14.6 20.3 16.7 16.8 35.7 17.6 12.9 17.7 25.6 9.5 10.4 12.0 15.0 14.4 20.7 20.2 21.8 18.5 12.0 16.8 10.6 14.0 21.7 17.9 89.5 14.4 25.8 11.3 9.2 14.9 14.8 10.6 10.9 11.2 16.8 28.1 16.9 17.4 11.8 15.4 26.0 19.7 22.3 13.1 19.0 14.5 15.7 18.4 5.9 14.1 22.0 9.9 9.8 12.7 17.3 10.8 13.0 12.7 13.7 3.7 17.3 17.1 10.3 5.6 15.2 2.9 10.8 10.1 4.6 4.6 10.8 27.9 3.2 10.4 13.0 22.3 12.5 9.2 12.7 6.7 7.9 12.5 31.7 7.7 9.2 9.9 21.7 5.1 7.1 11.8 14.7 10.9 7.0 7.3 16.7 26.0 16.9 14.0 12.6 10.4 13.8 3.0 12.9 11.2 21.2 12.9 2.4 27.5 7.2 15.8 10.5 22.3 19.7 16.4 21.7 17.1 13.7 17.3 16.9 19.4 15.4 19.0 16.3 4.8 13.1 20.8 26.0 18.7 14.5 18.8 19.0 19.0 26.4 17.6 12.9 12.0 15.0 12.0 10.9 FDFT1 ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839309 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favourable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favourable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" 20.8 44.3 26.3 22.7 27.7 30.6 57.5 19.5 43.6 27.6 41.7 45.9 20.0 44.6 26.9 29.1 59.4 27.5 19.9 27.1 29.8 32.1 24.9 45.9 30.7 23.4 36.2 34.4 22.9 18.0 17.1 18.2 22.1 47.4 38.8 32.9 32.4 46.5 20.6 71.2 38.4 30.2 18.0 56.5 18.4 35.4 41.3 40.5 25.9 24.7 32.2 25.4 25.8 34.2 44.0 30.5 42.2 19.6 22.6 31.0 29.0 21.6 10.5 47.1 18.8 10.2 17.5 14.3 8.5 14.5 9.0 18.7 14.7 26.8 30.1 4.2 8.5 18.0 23.3 71.0 7.3 5.0 24.9 14.1 8.0 35.0 21.7 7.3 9.9 15.7 18.0 20.1 10.0 11.3 20.3 39.7 8.8 14.1 25.7 17.4 41.2 6.2 15.8 10.9 61.8 41.8 78.8 15.1 9.4 7.4 12.6 21.3 20.7 21.3 14.1 4.2 10.5 1.9 5.3 8.2 20.7 32.8 7.4 24.8 12.4 42.2 19.6 22.6 21.6 17.2 20.8 44.0 22.7 21.2 30.5 35.3 21.5 20.3 18.6 22.6 11.7 22.7 31.0 29.0 26.3 27.7 19.5 43.6 29.8 32.1 36.2 34.4 47.4 40.5 FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol 2000000 Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavourable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" 21.0 57.8 19.3 17.6 26.5 16.5 19.8 12.8 32.2 19.0 25.0 22.6 14.5 45.9 18.0 21.7 41.4 16.7 18.8 19.6 18.6 23.4 23.7 100.8 25.7 19.2 19.5 24.3 15.2 27.5 15.6 12.3 20.2 47.3 16.5 29.7 20.5 29.2 12.9 15.7 29.3 32.3 18.9 23.0 17.7 23.4 15.1 16.5 25.1 19.5 41.7 27.3 13.7 20.8 41.1 39.7 49.4 37.1 45.3 45.5 48.3 35.6 19.4 71.3 25.7 16.7 61.3 25.4 17.0 33.7 27.2 44.3 31.4 84.9 27.2 41.4 14.9 39.8 42.4 147.8 25.5 14.8 30.4 15.8 34.6 37.8 27.5 25.5 18.1 43.6 23.4 43.2 21.7 47.3 28.1 73.3 28.3 38.3 32.6 24.8 42.8 28.4 28.2 30.9 75.4 71.6 23.8 27.7 23.7 17.5 31.9 29.4 23.0 69.4 34.4 15.2 18.7 9.4 31.1 31.1 23.9 48.5 14.8 27.2 23.9 30.5 36.0 49.4 39.4 37.1 35.0 41.1 34.8 39.8 39.7 34.2 31.5 39.3 16.5 45.3 27.2 31.4 45.5 48.3 19.3 26.5 12.8 32.2 18.6 23.4 19.5 24.3 47.3 16.5 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747822-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favourable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 13.4 5.7 5.5 6.1 13.4 1.8 5.2 6.0 5.0 9.7 6.7 1.4 16.8 2.5 6.5 19.3 8.2 4.6 5.3 4.6 4.8 4.8 7.2 3.6 12.2 1.9 4.9 2.2 7.2 3.0 18.5 15.9 5.7 3.1 6.8 3.6 5.0 4.5 21.9 5.0 6.6 3.5 7.2 6.2 8.1 4.1 15.9 2.6 3.9 10.2 12.8 2.8 7.7 9.0 10.5 5.4 8.0 5.1 1.2 2.8 1.1 4.6 1.6 5.7 9.0 3.4 5.2 3.6 5.6 5.5 3.3 3.9 9.5 2.9 7.5 3.5 6.7 3.3 3.1 7.0 7.5 3.1 4.2 4.9 7.2 3.4 2.3 2.7 4.2 3.1 3.9 7.9 9.0 4.9 6.1 5.6 4.2 1.3 2.1 0.8 0.8 3.3 1.7 5.5 44.2 3.2 1.6 1.9 2.8 9.2 0.5 6.0 2.2 1.2 7.2 6.4 4.9 3.2 4.4 4.8 7.1 2.9 4.0 0.8 3.0 8.0 5.1 5.4 1.7 3.1 2.8 10.5 1.0 1.8 2.8 3.8 1.6 2.0 0.4 1.2 2.4 5.4 2.1 1.1 5.5 13.4 6.0 4.2 4.8 4.8 4.9 2.2 3.1 2.6 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 60.8;lymphoid tissue: 49.7" "Cell line enhanced" "Detected in many" "HEL: 20.9;HL-60: 18.6;HMC-1: 39.8;NB-4: 24.4;THP-1: 36.6;U-937: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Group enriched" "Detected in many" 4 "dendritic cells: 32.6;granulocytes: 60.8;monocytes: 30.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavourable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 14.9 3.4 4.8 9.7 4.1 38.3 12.7 2.4 5.7 6.8 5.4 3.2 4.7 3.0 7.4 5.6 4.9 7.6 7.3 7.9 4.2 2.2 5.2 11.8 12.7 23.3 3.7 0.9 6.4 3.7 1.8 2.7 8.1 7.2 7.7 2.4 5.3 33.8 6.3 3.4 3.5 5.2 5.4 6.9 49.7 4.3 3.2 4.7 3.1 7.2 4.1 4.5 7.2 9.4 1.1 32.6 60.8 30.5 9.3 0.1 13.8 0.1 0.2 0.3 3.5 1.0 3.1 6.0 0.9 0.0 1.7 1.0 0.8 0.0 2.2 0.1 2.0 0.5 0.6 0.1 0.5 1.1 0.3 20.9 0.0 3.7 2.0 18.6 39.8 3.0 0.0 2.6 0.0 10.5 0.6 0.0 0.0 6.8 0.5 24.4 1.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 36.6 8.3 0.0 3.6 0.1 0.0 0.0 2.6 0.8 0.1 15.8 0.8 10.4 30.5 60.8 0.1 17.6 0.0 1.1 0.0 0.0 32.6 0.9 0.0 0.0 20.0 9.3 7.3 12.9 0.0 13.8 4.8 4.1 2.4 5.7 4.2 2.2 3.7 0.9 7.2 4.7 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38411138-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 109.2;BJ hTERT+: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved 120000000 "CAB033614: AB_783377, HPA056402: " "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 41.1 8.6 12.5 14.5 12.2 7.2 39.5 45.0 10.5 36.0 31.5 10.1 11.6 5.5 29.3 20.6 22.9 29.4 32.4 31.7 12.8 10.1 11.8 5.4 18.6 9.7 11.4 14.3 42.0 51.2 11.5 22.3 28.4 20.0 28.2 10.8 35.8 14.0 31.6 12.0 12.9 14.4 52.4 15.6 4.5 16.4 16.4 8.5 11.3 12.6 13.0 9.8 39.6 41.2 1.6 0.7 1.8 1.1 0.8 5.7 0.7 2.4 9.3 40.3 109.2 25.1 17.9 26.6 24.8 49.8 17.3 18.0 6.0 1.4 0.3 6.9 23.8 0.0 19.1 1.2 20.0 6.5 4.2 0.0 1.5 5.9 14.1 5.8 0.1 16.2 0.1 14.0 2.8 16.6 2.2 0.1 8.1 2.8 17.0 1.9 28.4 3.9 15.7 4.2 0.0 8.4 0.0 1.6 3.6 4.4 0.2 1.0 2.2 1.1 10.4 11.3 6.2 31.2 5.9 0.4 0.7 0.0 13.4 0.3 5.9 1.4 1.1 0.4 5.7 0.3 3.9 0.7 2.7 3.7 0.1 1.6 1.5 4.1 1.8 0.8 0.5 0.7 2.2 0.7 12.5 12.2 45.0 10.5 12.8 10.1 11.4 14.3 20.0 8.5 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478334-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.8" "Cell line enhanced" "Detected in some" "AN3-CA: 57.8;BEWO: 19.4;CACO-2: 15.1;HaCaT: 17.4;HAP1: 18.7;NTERA-2: 18.5;T-47d: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 10.8;eosinophil: 4.6" "Lineage enriched" "Detected in single" 35 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" 500000 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favourable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favourable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 2.1 8.8 16.4 3.0 30.3 0.0 9.9 15.8 21.3 6.8 14.1 55.7 5.6 4.2 22.0 6.6 10.2 12.5 12.5 1.4 20.6 11.1 11.4 16.1 13.1 1.0 41.2 13.3 7.4 12.8 25.5 2.5 6.2 30.2 11.7 8.7 16.4 23.8 24.3 0.4 45.4 4.7 18.3 74.8 0.5 9.3 2.9 32.1 0.8 23.4 1.6 3.4 6.9 8.5 0.1 0.1 10.8 0.1 0.1 0.3 0.0 2.2 0.1 9.0 57.8 0.0 0.0 19.4 0.1 0.0 0.0 0.0 15.1 0.3 0.0 4.1 0.9 17.4 18.7 4.0 0.0 0.0 4.0 0.0 0.0 0.3 0.4 0.0 3.8 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 18.5 0.0 0.0 0.0 2.2 5.6 4.9 0.1 0.1 0.1 10.6 0.0 15.5 0.0 0.0 0.1 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 10.8 0.1 4.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 16.4 30.3 15.8 21.3 20.6 11.1 41.2 13.3 30.2 32.1 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease mutation, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 131.7" "Cell line enhanced" "Detected in many" "CACO-2: 19.1;HaCaT: 14.9;Hep G2: 32.1;NTERA-2: 15.6;RT4: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 670000 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: " "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.5 1.5 24.7 1.7 30.3 1.6 4.2 10.2 22.0 4.1 4.9 15.8 3.4 9.9 1.8 2.7 26.9 2.0 5.0 2.0 21.6 11.7 9.6 7.4 4.5 1.3 17.6 21.5 1.1 23.0 1.2 3.0 5.6 15.1 3.7 3.8 1.7 3.8 9.0 1.7 131.7 7.4 1.3 9.0 2.1 4.9 8.1 10.6 0.1 1.3 8.5 7.3 8.5 10.1 0.1 0.6 0.1 0.1 0.2 0.3 0.0 0.0 1.5 9.0 2.6 0.0 0.1 9.2 1.0 0.1 0.4 0.2 19.1 0.4 0.0 7.6 0.3 14.9 2.6 0.1 0.1 0.1 9.6 5.9 1.5 32.1 0.0 0.0 0.1 0.0 5.0 0.1 0.0 0.0 6.4 0.0 0.0 9.5 0.3 0.2 15.6 0.0 0.5 0.5 0.1 1.3 19.1 2.6 0.7 0.8 1.6 0.0 8.9 1.1 0.4 0.0 0.9 0.2 0.6 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.6 0.1 0.0 24.7 30.3 10.2 22.0 21.6 11.7 17.6 21.5 15.1 10.6 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086886-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 33.6;kidney: 37.7;liver: 45.3" "Group enriched" "Detected in many" 4 "CACO-2: 42.0;Hep G2: 42.0;RH-30: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "neutrophil: 3.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" 4300000 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 0.5 5.7 0.7 14.3 0.6 0.1 1.6 2.6 0.5 2.8 10.4 0.9 0.7 13.5 0.9 4.8 1.6 1.7 33.6 0.7 0.8 0.3 37.7 45.3 25.3 2.5 0.7 1.0 13.6 26.0 0.0 0.7 1.3 0.8 4.0 3.7 2.0 1.6 0.3 4.3 0.5 17.3 1.6 0.8 11.2 5.4 2.9 0.4 0.3 0.8 2.3 0.7 1.9 3.6 1.1 0.9 3.0 1.1 0.4 0.4 0.0 0.7 11.8 0.2 2.9 0.0 0.0 5.8 0.0 0.0 0.0 0.0 42.0 1.6 1.2 5.5 0.0 0.6 2.3 0.4 0.0 0.7 2.8 0.1 0.6 42.0 1.3 0.1 1.0 0.2 0.0 2.1 0.0 0.0 3.9 0.1 0.9 9.6 0.0 0.8 7.1 1.0 1.9 67.6 7.1 5.7 0.1 0.4 0.7 0.4 3.0 1.4 2.9 0.6 0.2 0.0 5.7 0.0 0.1 0.4 0.4 0.7 0.0 0.2 0.5 1.5 1.1 0.4 0.4 0.3 0.3 1.1 0.4 0.0 0.1 0.6 0.4 0.4 3.0 0.4 0.3 0.9 0.2 0.0 0.7 0.6 2.6 0.5 0.8 0.3 0.7 1.0 0.8 0.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635277 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 20.8;blood: 68.0;bone marrow: 73.6;lung: 30.9;lymphoid tissue: 54.3" "Group enriched" "Detected in some" 4 "Daudi: 29.4;U-266/70: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 20.8 2.6 2.2 23.6 4.5 73.6 5.6 1.1 4.2 2.9 2.8 1.5 4.2 1.6 4.0 2.3 2.2 6.3 5.3 8.5 2.6 2.3 3.0 4.2 30.9 34.1 6.6 1.7 1.9 2.4 0.4 1.2 3.3 4.2 2.5 1.8 2.1 2.9 2.6 4.4 1.7 3.7 6.4 4.8 54.3 2.5 2.6 4.1 1.9 2.9 2.5 7.8 5.1 6.1 13.3 28.9 40.8 68.0 36.3 29.6 55.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 54.6 0.7 2.2 0.0 6.7 0.0 3.1 52.4 32.3 29.6 68.0 1.7 7.7 2.6 13.6 28.9 13.3 1.3 12.8 40.8 36.3 55.6 1.3 0.1 55.0 2.2 4.5 1.1 4.2 2.6 2.3 6.6 1.7 4.2 4.1 FICD "HIP13, HYPE" ENSG00000198855 "FIC domain containing" Q9BVA6 12 108515185-108525837 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" "Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021390, HPA071134" Approved Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA021390: AB_1851340, HPA071134: " "unprognostic (1.00e-1)" "unprognostic (8.76e-2)" "unprognostic (1.76e-2)" "prognostic favourable (4.61e-5)" "unprognostic (6.92e-2)" "unprognostic (2.68e-2)" "unprognostic (5.73e-2)" "unprognostic (2.84e-2)" "unprognostic (8.68e-2)" "unprognostic (2.57e-1)" "unprognostic (3.15e-2)" "unprognostic (1.19e-1)" "unprognostic (7.66e-2)" "unprognostic (1.56e-2)" "unprognostic (6.22e-2)" "unprognostic (3.12e-2)" "unprognostic (3.65e-2)" 4.2 9.6 5.6 6.1 8.2 3.0 4.5 4.0 6.7 8.5 3.8 7.3 10.5 3.9 4.6 15.8 2.3 4.1 4.1 3.5 5.4 5.9 5.2 16.4 5.0 4.9 8.9 5.1 4.8 27.9 4.8 15.3 7.9 6.0 6.1 3.6 10.2 19.7 7.9 2.6 3.4 3.3 4.6 7.5 4.8 5.1 8.5 6.6 5.4 13.6 1.0 6.2 4.1 4.5 5.0 15.2 10.9 5.4 3.1 8.0 1.8 1.9 4.7 1.9 3.8 4.6 3.2 5.3 12.5 6.6 5.9 4.2 2.9 1.9 2.6 4.7 5.9 2.5 2.0 1.4 5.3 4.4 3.1 1.5 3.6 4.1 18.2 2.2 5.6 1.5 3.0 8.3 11.9 4.2 1.0 9.0 5.2 4.3 2.9 2.3 2.1 7.9 1.7 2.6 6.4 2.8 3.7 1.8 1.3 5.6 2.6 6.1 4.2 2.1 4.7 6.1 2.2 10.6 4.8 17.9 2.9 0.9 8.4 1.9 4.2 10.9 2.8 4.2 6.8 4.8 8.0 5.0 5.0 6.2 2.7 3.3 2.9 5.6 5.5 3.1 5.4 15.2 3.1 1.8 5.6 8.2 4.0 6.7 5.4 5.9 8.9 5.1 6.0 6.6 FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA028476: AB_10599974, HPA028486: AB_10600206, HPA028563: AB_10602286" "unprognostic (2.64e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (7.34e-2)" "unprognostic (1.45e-1)" "prognostic unfavourable (3.04e-4)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (8.08e-2)" "unprognostic (6.51e-2)" "unprognostic (9.74e-2)" "prognostic unfavourable (2.55e-6)" "unprognostic (1.67e-2)" "unprognostic (5.06e-2)" "unprognostic (5.50e-2)" "unprognostic (1.17e-2)" 16.5 16.5 20.3 15.5 18.9 12.1 17.4 15.9 20.8 14.1 16.4 19.3 14.7 19.6 15.9 21.2 19.8 16.7 11.8 16.1 18.2 10.4 19.0 36.5 13.5 20.0 20.8 15.6 14.5 19.0 13.6 12.0 18.5 15.9 18.7 19.0 16.1 16.2 16.3 26.3 23.3 23.9 17.6 12.4 22.9 16.1 19.1 18.9 15.7 20.8 18.4 22.0 15.5 15.4 25.1 24.5 15.2 24.1 14.9 26.4 22.7 13.1 21.2 13.5 23.0 11.8 8.7 25.7 10.0 8.3 14.6 12.5 18.8 16.3 15.4 20.2 9.2 17.3 25.8 20.7 9.5 16.0 19.4 12.5 16.8 13.2 16.1 18.0 16.3 12.4 27.2 16.6 17.8 16.9 20.0 12.5 12.3 28.4 12.4 12.6 29.4 22.0 20.9 6.7 35.3 13.9 18.4 22.8 31.3 15.6 35.4 19.7 30.3 27.4 10.7 9.2 12.7 11.8 15.7 19.6 24.3 26.5 11.1 14.7 14.7 15.2 23.0 14.8 24.0 20.9 26.4 25.1 22.1 22.7 24.1 20.5 20.5 20.2 5.2 14.9 24.1 24.5 23.3 22.7 20.3 18.9 15.9 20.8 18.2 10.4 20.8 15.6 15.9 18.9 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related tyrosine kinase 1" P17948 13 28300344-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "placenta: 155.3" "Cell line enhanced" "Detected in some" "BJ: 17.0;BJ hTERT+: 13.5;HMC-1: 84.6;HUVEC TERT2: 15.3;WM-115: 30.3" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.1;naive B-cell: 3.7;neutrophil: 2.1" "Group enriched" "Detected in many" 5 "B-cells: 3.7;granulocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" 875697 54000 "Plasma membrane, Actin filaments" "CAB068189: , CAB068190: , HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 18.9 4.0 9.9 4.0 14.3 1.2 13.5 8.0 15.9 7.1 4.6 3.5 1.7 3.5 7.2 2.2 3.4 4.0 6.9 18.3 11.4 7.3 10.3 7.6 12.3 2.5 10.3 3.2 5.1 5.4 13.4 3.7 155.3 13.8 5.1 3.1 9.1 3.0 5.0 12.5 2.6 3.4 7.3 9.6 7.2 4.6 6.8 10.2 0.0 19.1 3.8 2.8 7.6 9.2 3.7 0.5 2.1 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 17.0 13.5 6.2 3.6 0.0 0.0 0.0 0.0 2.2 0.0 1.6 0.0 11.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 84.6 0.1 0.0 0.0 0.2 15.3 0.4 0.0 0.0 0.0 1.0 0.8 9.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 30.3 0.2 0.1 0.1 0.1 0.1 0.0 1.1 0.1 0.1 0.0 3.7 0.4 0.4 2.1 0.2 0.1 0.5 0.2 0.2 9.9 14.3 8.0 15.9 11.4 7.3 10.3 3.2 13.8 10.2 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.9;brain: 19.3;lymphoid tissue: 15.0" "Group enriched" "Detected in some" 11 "REH: 27.8;THP-1: 17.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 19.3" "Group enriched" "Detected in some" 11 "myeloid DC: 29.9;plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 16 "dendritic cells: 29.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" 180000 "Endoplasmic reticulum" "HPA047539: " "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.9 0.6 0.6 7.2 1.1 7.5 2.6 19.3 3.5 0.9 1.2 0.1 0.1 0.4 0.8 0.8 1.0 1.2 4.6 0.5 0.9 1.7 2.8 0.7 2.7 15.0 1.8 1.1 0.5 5.7 0.0 0.4 0.0 7.4 0.6 1.4 0.1 2.3 0.6 0.4 1.2 3.0 1.3 4.4 8.8 0.9 1.2 0.0 8.2 0.6 0.0 5.8 2.4 0.7 0.1 29.9 1.4 1.8 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.5 0.0 27.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 1.4 0.0 0.3 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 0.0 0.8 0.0 12.1 0.0 1.2 0.6 1.1 19.3 3.5 0.9 1.7 1.8 1.1 7.4 0.0 FLT4 "PCL, VEGFR3" ENSG00000037280 "Fms related tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 56.3" "Cell line enhanced" "Detected in some" "AN3-CA: 8.3;BEWO: 10.2;HEK 293: 12.6;HL-60: 7.4;HUVEC TERT2: 8.1;T-47d: 12.0;TIME: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "MAIT T-cell: 7.7" "Lineage enriched" "Detected in single" 35 "T-cells: 7.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted to blood" 270000000 "Plasma membrane" "Nucleoplasm, Cell Junctions" "CAB000099: , HPA046519: , HPA067906: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 14.8 7.1 1.6 4.9 6.0 0.7 28.5 1.3 2.7 6.3 7.3 1.9 2.1 3.1 7.3 6.2 5.7 9.2 5.3 6.4 1.7 0.9 11.7 10.2 14.1 23.6 2.0 0.8 5.8 2.3 2.3 6.2 56.3 2.1 4.9 1.4 6.7 3.3 4.4 4.8 2.8 4.7 4.7 1.5 14.5 2.4 3.5 2.0 0.3 19.4 4.4 2.3 6.1 14.7 0.0 0.1 0.2 0.0 0.0 7.7 0.2 0.1 2.0 2.7 8.3 0.0 0.0 10.2 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.8 0.1 0.3 2.8 0.1 0.2 0.1 12.6 1.0 0.4 0.4 0.1 7.4 0.2 0.2 0.0 0.1 0.3 8.1 0.3 0.3 1.7 4.5 0.1 0.4 5.8 0.5 6.5 0.0 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.0 12.0 0.2 12.7 0.1 5.9 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.9 0.0 7.7 0.0 0.4 1.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 1.6 6.0 1.3 2.7 1.7 0.9 2.0 0.8 2.1 2.0 FNTA "FPTA, PGGT1A, PTAR2" ENSG00000168522 "Farnesyltransferase, CAAX box, alpha" P49354 8 43034194-43085788 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010149, HPA018830" Approved Approved Cytosol 220000 Cytosol "CAB010149: AB_2106299, HPA018830: AB_1848992" "unprognostic (2.09e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-1)" "unprognostic (1.86e-3)" "unprognostic (2.64e-1)" "unprognostic (4.70e-3)" "unprognostic (1.83e-2)" "unprognostic (3.69e-2)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (3.25e-2)" "unprognostic (4.10e-1)" "prognostic unfavourable (2.94e-12)" "unprognostic (3.63e-2)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (1.29e-3)" 32.5 21.5 25.3 20.9 31.9 15.3 29.8 21.2 28.8 26.7 25.7 36.9 25.0 23.7 23.7 29.4 28.0 22.9 18.1 32.6 25.6 23.1 24.0 30.5 22.7 27.4 43.3 23.8 21.5 26.0 17.9 24.7 32.6 33.4 25.1 22.5 14.1 23.6 25.9 45.2 29.7 20.4 23.9 75.9 22.9 20.9 18.3 36.8 26.0 25.4 26.8 28.1 27.1 29.8 11.7 11.7 11.1 8.9 13.9 11.9 5.3 23.5 11.7 16.1 5.2 28.4 37.0 13.4 13.7 16.1 16.1 14.8 18.9 18.2 27.7 10.6 17.2 12.9 19.8 22.8 18.9 7.2 13.1 21.7 8.0 16.3 37.0 8.8 11.6 28.6 37.3 11.5 33.1 27.6 26.2 16.3 17.6 2.8 21.1 13.5 28.0 8.5 18.5 25.6 14.9 22.0 17.5 9.6 14.9 17.8 14.8 23.5 18.8 16.8 22.1 5.4 7.1 21.8 14.5 15.2 12.9 27.1 14.2 17.2 12.6 3.0 6.6 11.1 8.7 8.9 10.3 11.7 9.1 11.7 11.7 11.6 11.9 11.9 1.6 13.9 6.7 11.0 11.5 5.3 25.3 31.9 21.2 28.8 25.6 23.1 43.3 23.8 33.4 36.8 FNTB FPTB ENSG00000257365 "Farnesyltransferase, CAAX box, beta" P49356 14 64986720-65062652 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 75.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062743 Uncertain Approved Centrosome Centrosome "HPA062743: " "unprognostic (2.79e-1)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (8.57e-3)" "unprognostic (1.88e-1)" "unprognostic (6.88e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (6.21e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-2)" "unprognostic (1.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-3)" "unprognostic (2.36e-2)" "unprognostic (3.60e-1)" "unprognostic (5.56e-2)" "unprognostic (1.11e-3)" 7.4 9.0 6.3 4.9 21.9 2.3 7.8 11.4 13.7 8.0 6.3 24.3 6.2 5.6 6.4 6.6 13.5 9.0 5.1 12.0 8.1 7.9 8.0 5.6 7.0 5.1 34.0 7.2 7.4 5.9 13.6 7.9 8.2 25.4 8.9 7.9 4.4 8.0 9.6 14.3 10.3 5.1 11.6 75.0 4.6 5.7 9.0 22.2 4.7 5.6 5.8 7.3 7.4 7.8 2.4 6.4 12.3 10.3 2.8 8.8 5.3 18.3 13.4 10.4 5.9 6.7 5.9 7.6 10.6 7.8 12.0 12.4 7.1 7.6 3.1 6.1 11.2 12.2 25.0 8.3 9.9 4.4 7.0 12.4 3.6 10.3 4.4 4.2 17.2 5.0 7.2 5.2 2.8 10.0 6.7 4.5 7.0 12.1 6.4 7.0 4.5 13.6 6.3 9.7 3.9 8.3 6.8 6.6 6.6 6.6 13.0 14.4 12.0 7.4 7.9 8.7 18.0 3.9 6.8 2.3 2.6 3.2 10.1 5.5 20.1 12.3 10.3 9.2 3.6 8.6 8.8 2.4 5.5 4.3 6.4 1.9 4.5 3.3 2.7 2.8 4.3 4.9 5.1 5.3 6.3 21.9 11.4 13.7 8.1 7.9 34.0 7.2 25.4 22.2 FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198212-74234086 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Uncertain Vesicles Vesicles "HPA072331: " "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (8.18e-3)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (7.88e-2)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" 14.6 11.6 10.9 9.1 12.6 3.4 13.0 19.0 15.8 15.9 11.7 13.0 7.5 11.5 17.7 11.1 15.7 15.4 13.3 12.8 10.9 7.1 15.9 13.7 10.8 8.0 15.5 10.6 14.1 10.2 14.2 27.7 10.6 14.4 11.1 11.3 10.6 11.7 9.1 15.7 12.0 12.0 11.8 16.3 11.0 12.3 8.7 13.9 6.6 20.0 6.8 9.2 17.9 12.9 4.3 9.2 15.2 14.9 3.8 5.4 7.4 9.2 7.7 5.8 8.5 13.5 12.7 8.7 12.2 8.1 8.4 10.0 4.3 7.0 5.7 15.1 7.2 7.8 10.4 11.1 13.4 11.5 4.4 12.9 9.3 7.2 11.3 9.8 9.9 10.4 14.5 8.4 4.0 8.7 13.2 6.8 13.2 2.4 5.4 2.0 6.3 7.0 5.8 13.6 8.0 7.4 6.7 6.1 6.1 9.0 13.2 14.0 15.9 11.2 7.8 3.7 7.1 20.2 9.2 7.5 5.3 7.6 15.0 9.7 12.5 12.0 14.9 15.2 4.3 14.5 5.0 3.6 4.4 3.9 9.2 4.3 4.9 4.4 4.4 3.8 12.5 0.9 5.4 7.4 10.9 12.6 19.0 15.8 10.9 7.1 15.5 10.6 14.4 13.9 FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060758 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.4" "Cell line enhanced" "Detected in many" "RT4: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB025217, HPA030479" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB025217: , HPA030479: " "unprognostic (7.70e-3)" "unprognostic (1.99e-2)" "unprognostic (1.11e-1)" "unprognostic (4.68e-3)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (4.23e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "prognostic favourable (9.66e-7)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" 1.5 2.2 0.8 3.0 1.3 1.3 2.6 0.5 0.8 6.4 21.4 0.2 10.2 6.8 1.6 9.0 10.5 2.8 7.3 3.3 1.2 0.8 23.7 19.6 5.6 0.6 1.5 0.5 2.4 5.9 0.3 3.8 2.7 0.8 4.1 5.5 0.8 9.2 6.1 2.9 2.0 41.4 2.5 2.4 1.0 5.5 1.8 0.5 1.2 1.0 5.2 7.4 5.0 3.6 2.2 1.2 3.8 1.2 1.4 2.3 0.3 3.2 5.3 0.8 1.3 0.4 0.4 1.0 0.8 0.2 0.1 0.1 4.1 5.1 1.3 4.9 0.8 7.7 0.4 1.5 0.2 4.4 0.5 1.8 4.6 3.5 0.3 1.2 1.1 0.3 2.2 0.5 0.6 0.3 0.9 3.3 1.3 1.8 1.0 0.8 1.4 0.9 1.5 4.6 1.6 6.5 10.1 1.1 1.2 1.1 6.8 0.7 2.1 1.0 1.3 1.5 1.6 1.2 0.8 5.0 3.5 2.3 1.5 0.8 1.0 3.2 1.0 1.0 1.9 0.6 2.3 1.1 1.4 1.7 0.4 2.2 1.1 1.4 3.8 1.4 1.2 1.2 1.0 0.3 0.8 1.3 0.5 0.7 1.2 0.8 1.5 0.5 0.8 0.5 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 126.8" "Cell line enriched" "Detected in some" 29 "Hep G2: 44.4" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "T-reg: 2.5" "Lineage enriched" "Detected in single" 25 "T-cells: 2.5" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" 580000 Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favourable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favourable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favourable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.2 0.0 0.6 0.2 1.6 0.0 0.2 0.2 0.7 0.2 0.3 0.2 0.2 0.3 0.2 2.0 0.2 0.0 0.2 0.2 0.5 0.4 25.9 126.8 0.2 0.2 0.4 0.2 0.2 1.0 0.0 0.2 0.2 0.2 0.3 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.2 0.1 1.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 44.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 2.5 0.1 0.6 1.6 0.2 0.7 0.5 0.4 0.4 0.2 0.2 0.2 FTSJ1 "CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7" ENSG00000068438 "FtsJ RNA methyltransferase homolog 1" Q9UET6 X 48476021-48486364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002718 Approved Approved Cytosol Cytosol "HPA002718: AB_1078914" "unprognostic (2.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.44e-1)" "unprognostic (3.37e-1)" "unprognostic (2.13e-1)" "unprognostic (6.77e-2)" "prognostic unfavourable (1.74e-5)" "unprognostic (1.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.96e-3)" "unprognostic (2.06e-3)" "unprognostic (7.82e-2)" "prognostic unfavourable (5.24e-10)" "unprognostic (2.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" 17.6 19.4 12.3 18.2 21.6 18.4 17.1 18.7 21.2 23.3 11.7 13.6 20.8 10.7 18.5 12.6 19.0 15.9 12.8 15.0 9.9 10.3 15.9 21.3 16.9 22.9 13.6 9.2 17.4 36.6 13.9 16.2 11.3 14.9 13.3 10.6 12.4 20.8 18.6 17.3 18.0 12.0 16.6 11.0 19.6 17.8 14.6 15.2 17.2 20.0 24.8 18.6 17.3 17.2 17.1 16.8 10.7 16.1 15.9 26.9 15.1 25.5 17.7 6.8 26.9 9.7 10.2 11.1 12.6 12.1 18.4 14.6 10.5 35.9 14.9 9.4 19.2 17.3 13.5 44.3 8.3 11.3 12.7 9.5 22.4 11.8 27.7 13.0 24.0 9.5 22.4 23.1 22.8 12.8 8.0 12.5 23.8 14.5 16.8 9.3 15.3 30.4 13.7 22.2 30.9 17.3 8.6 9.2 9.1 20.0 11.0 9.2 12.6 7.5 12.5 14.6 19.8 30.3 15.3 16.9 13.1 10.7 32.2 24.5 15.2 9.2 14.1 10.7 21.9 16.1 26.9 17.1 18.9 22.1 16.8 16.9 17.3 21.9 2.0 15.9 15.1 11.6 17.5 15.1 12.3 21.6 18.7 21.2 9.9 10.3 13.6 9.2 14.9 15.2 FUK FLJ39408 ENSG00000157353 Fucokinase Q8N0W3 16 70454421-70480274 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles Vesicles "HPA041971: AB_10795648" "unprognostic (4.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.73e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (4.82e-3)" "unprognostic (4.85e-2)" "prognostic favourable (8.91e-4)" "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (8.89e-2)" "prognostic favourable (8.38e-4)" 6.7 11.3 11.5 9.8 13.2 8.5 7.3 13.9 13.5 7.5 12.1 15.5 15.1 18.5 8.3 11.5 8.2 10.8 9.4 7.2 9.4 7.4 13.1 11.9 8.1 9.1 12.5 12.4 10.5 12.2 17.1 16.4 11.0 9.8 9.1 7.7 12.9 10.8 9.4 9.0 13.0 13.1 6.3 9.3 9.7 12.2 6.1 12.5 7.2 12.0 4.2 11.1 7.6 6.8 4.3 3.2 3.9 4.4 2.9 6.7 2.5 3.0 4.3 2.6 5.6 1.5 1.8 9.7 1.8 2.9 2.4 3.1 3.8 10.1 2.2 8.6 1.7 4.5 1.7 4.4 1.5 4.1 6.2 2.8 7.9 4.4 3.7 3.6 2.1 3.0 5.3 1.8 4.5 4.4 5.4 2.7 1.8 9.7 4.3 8.4 1.6 2.4 6.4 0.6 9.6 6.1 5.4 4.2 5.0 10.1 3.5 5.1 14.8 7.1 4.6 1.9 2.5 4.1 2.0 9.5 4.5 4.5 3.4 3.5 4.2 0.6 4.4 1.8 4.8 2.5 4.1 1.9 4.8 4.8 2.7 4.3 6.7 3.1 3.9 2.9 2.8 3.2 3.2 2.5 11.5 13.2 13.9 13.5 9.4 7.4 12.5 12.4 9.8 12.5 FUT1 "H, HSC" ENSG00000174951 "Fucosyltransferase 1 (H blood group)" P19526 19 48748011-48755390 "Blood group antigen proteins, Enzymes, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 19.5" "Cell line enhanced" "Detected in many" "CACO-2: 8.1;HEL: 10.1;hTCEpi: 8.0;RT4: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (2.90e-2)" "unprognostic (3.09e-2)" "unprognostic (8.05e-3)" "unprognostic (4.65e-3)" "unprognostic (2.92e-3)" "unprognostic (8.73e-2)" "unprognostic (2.58e-2)" "unprognostic (3.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (4.19e-2)" "unprognostic (1.29e-1)" "prognostic favourable (3.99e-4)" "unprognostic (1.33e-1)" "unprognostic (3.22e-2)" "unprognostic (8.67e-3)" "unprognostic (3.98e-2)" 2.5 0.8 0.9 0.9 0.9 1.5 1.6 3.5 1.4 0.9 0.9 0.9 0.9 1.0 0.9 0.9 1.5 1.2 0.9 1.4 0.9 0.2 1.1 0.9 6.8 0.9 0.9 0.9 0.9 19.5 1.0 1.7 2.8 0.9 0.9 0.0 0.9 0.9 0.9 0.9 0.8 0.9 0.9 0.9 3.4 7.6 0.9 0.9 0.9 1.0 0.9 0.9 0.9 0.9 0.9 0.9 3.3 0.7 1.5 0.6 0.3 3.2 0.1 0.1 0.2 0.0 0.0 1.7 0.2 0.1 0.2 0.2 8.1 4.7 0.3 0.3 0.2 5.5 1.6 5.0 0.1 0.0 0.8 10.1 0.4 0.1 2.4 0.4 4.5 0.0 8.0 0.4 3.7 3.5 0.5 1.5 0.0 3.7 0.2 6.2 0.9 0.4 0.3 0.0 1.6 0.3 9.7 7.6 0.5 0.4 7.0 0.1 4.6 0.2 3.5 0.3 2.5 0.2 0.3 1.4 3.6 1.0 0.1 0.3 0.3 3.3 0.7 0.5 0.5 0.3 0.3 0.8 0.6 0.4 0.3 0.9 0.6 0.5 2.1 1.5 0.3 0.9 0.2 0.3 0.9 0.9 3.5 1.4 0.9 0.2 0.9 0.9 0.9 0.9 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705950 "Blood group antigen proteins, Enzymes, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.3;salivary gland: 58.1" "Cell line enriched" "Detected in some" 6 "CAPAN-2: 40.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebellum: 8.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favourable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.4 0.6 0.7 5.3 0.8 0.0 0.8 8.7 1.6 9.3 25.0 0.3 13.9 24.1 1.3 0.1 16.0 1.2 23.3 0.5 0.7 0.7 0.8 0.4 1.1 0.1 0.7 0.1 1.0 7.5 0.0 1.5 0.2 0.7 1.2 10.9 0.1 58.1 14.5 0.5 2.6 41.3 0.4 0.7 0.6 15.8 0.7 0.2 0.5 0.6 16.1 19.3 3.1 5.4 1.7 1.8 3.5 1.0 1.4 2.5 0.6 1.1 1.0 0.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.8 40.9 0.3 0.3 0.0 7.2 0.0 0.0 0.0 0.4 0.3 0.4 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.5 0.9 0.3 0.3 0.3 0.1 1.8 0.0 0.3 2.2 0.3 0.1 0.3 0.0 6.1 0.0 0.1 0.2 0.3 0.3 0.1 0.3 0.2 0.0 0.2 0.2 0.1 3.5 0.8 0.4 2.0 0.7 1.1 1.5 2.3 1.0 0.5 1.7 2.1 0.7 3.4 1.4 1.0 1.8 2.5 0.6 0.7 0.8 8.7 1.6 0.7 0.7 0.7 0.1 0.7 0.2 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.6;intestine: 49.3;lymphoid tissue: 38.4" "Group enriched" "Detected in some" 4 "A-431: 30.2;RH-30: 10.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" HPA046966 Supported "HPA046966: " "prognostic unfavourable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favourable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.2 0.1 0.2 14.5 0.2 0.0 0.4 0.2 0.2 10.9 40.4 0.2 32.5 18.8 0.4 0.5 53.6 0.7 21.5 0.1 0.2 0.2 3.8 0.9 5.1 0.1 0.2 0.1 0.5 4.7 0.0 0.3 0.6 0.1 1.0 18.1 0.2 27.5 31.6 0.1 1.0 49.3 1.0 0.2 0.1 8.1 1.3 0.1 0.3 0.1 14.9 38.4 2.9 16.1 0.2 1.6 0.8 0.6 0.0 0.5 0.0 30.2 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.4 0.0 1.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.2 1.0 0.0 0.5 0.0 0.1 0.0 4.8 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.8 0.0 0.0 1.6 0.5 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.1 FUT5 FUC-TV ENSG00000130383 "Fucosyltransferase 5" Q11128 19 5865826-5870540 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6" "Cell line enhanced" "Detected in some" "MCF7: 1.8;SH-SY5Y: 2.9;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046966 Uncertain "HPA046966: " "unprognostic (7.72e-2)" "unprognostic (3.59e-1)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" 0.2 0.1 1.0 0.1 0.5 3.6 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.5 0.3 0.3 1.1 0.4 0.3 0.2 1.1 0.1 0.2 0.9 0.2 0.5 0.1 0.3 0.1 0.1 0.1 0.4 0.1 1.2 0.5 0.1 0.1 0.8 0.2 0.1 1.6 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830610-5839731 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;intestine: 44.4;lymphoid tissue: 33.9;salivary gland: 37.0" "Group enriched" "Detected in some" 7 "Hep G2: 14.6;RPMI-8226: 5.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 3.7;neutrophil: 1.2;NK-cell: 2.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.7;NK-cells: 2.1" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Golgi apparatus" "HPA043707: , HPA046966: " "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favourable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favourable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.2 0.2 0.2 7.2 0.2 0.1 0.8 0.2 0.2 9.2 26.4 0.0 9.5 15.6 0.7 7.6 40.8 0.6 25.4 0.2 0.2 0.2 27.2 6.5 1.3 0.2 0.2 0.0 0.2 2.2 0.0 0.8 0.0 0.0 0.3 6.9 0.0 37.0 19.1 0.2 0.2 44.4 0.2 0.2 0.2 2.8 0.3 0.0 0.0 0.2 16.4 33.9 0.2 12.4 0.4 0.3 3.7 0.3 2.1 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.2 14.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 5.4 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.1 3.7 0.3 0.4 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.3 0.2 1.2 2.1 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 13.5;NK-cells: 12.0;T-cells: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA040863, HPA043410" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA040863: , HPA043410: " "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.65e-3)" "unprognostic (2.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (2.00e-2)" "unprognostic (1.33e-3)" "unprognostic (8.09e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" 7.2 7.6 16.2 12.0 21.1 3.3 9.4 24.1 18.1 6.7 9.8 29.1 16.1 15.4 8.7 5.0 6.5 14.0 10.1 5.2 19.8 12.9 6.2 2.9 7.0 11.2 20.5 11.2 7.2 10.5 6.2 5.2 18.8 17.3 5.4 10.4 7.1 33.7 13.7 3.5 4.9 15.1 9.5 39.8 8.5 27.6 13.1 23.6 8.4 7.5 2.4 15.2 14.4 5.6 13.5 2.2 0.5 1.7 12.0 8.2 2.5 34.9 6.9 3.3 30.7 14.8 11.2 20.8 11.2 17.2 7.8 8.7 5.4 12.9 9.3 9.6 11.1 2.6 7.9 3.1 12.0 34.5 3.4 9.4 2.5 7.0 7.6 2.1 7.7 28.1 2.0 10.8 5.1 19.8 3.4 7.9 5.6 18.0 9.9 5.1 4.5 24.2 6.8 2.9 5.3 14.0 9.8 7.1 5.3 6.0 2.8 2.4 2.8 3.4 43.1 10.3 11.0 4.5 9.1 15.9 6.0 22.2 20.8 3.7 3.2 0.5 1.7 0.5 3.5 0.6 3.5 13.5 5.6 5.1 2.2 6.8 6.1 6.0 0.2 12.0 1.1 2.2 8.2 2.5 16.2 21.1 24.1 17.3 19.8 12.9 20.5 11.2 17.3 23.6 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "NK-cells: 15.3;T-cells: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" 2000000 "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: " "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favourable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavourable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 29.1 7.2 49.2 29.0 38.4 16.3 18.1 33.9 62.1 25.7 12.1 33.7 4.1 10.1 21.8 21.4 10.2 32.0 19.4 21.2 39.4 34.0 9.5 12.2 25.2 57.2 35.7 23.1 18.6 4.4 15.0 12.5 17.7 25.6 9.6 10.0 11.0 6.4 8.4 7.0 16.5 19.0 24.2 30.9 39.8 15.4 10.1 31.3 34.8 27.5 5.6 38.5 22.6 19.3 1.6 1.7 0.7 1.5 15.3 43.2 10.7 1.9 0.2 34.2 5.7 26.2 16.1 0.6 5.4 17.1 4.6 8.3 0.2 0.3 3.8 3.5 10.4 0.2 4.8 7.5 9.1 0.1 12.6 10.5 2.5 0.5 15.5 3.5 3.6 15.4 11.3 17.4 14.9 18.8 0.8 26.8 16.4 0.2 16.7 3.2 4.9 3.4 5.3 4.6 0.2 0.0 1.7 24.0 9.7 1.0 0.4 22.8 0.2 10.6 11.9 14.0 2.6 103.1 3.4 3.8 3.5 5.9 26.4 8.2 24.3 0.2 1.5 0.0 34.1 1.2 43.2 1.1 21.2 37.5 1.7 1.6 7.0 18.7 0.7 15.3 0.9 1.0 17.6 10.7 49.2 38.4 33.9 35.3 39.4 34.0 35.7 23.1 25.6 31.3 G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559123-30620063 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Approved Approved "Golgi apparatus,Vesicles,Cytosol" Cytosol "Golgi apparatus, Vesicles" "HPA001601: AB_1079198" "unprognostic (4.75e-2)" "unprognostic (6.31e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (9.10e-2)" "unprognostic (3.99e-2)" "unprognostic (5.44e-6)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.12e-2)" 7.6 5.1 5.6 7.6 14.2 8.5 6.6 10.8 10.4 8.1 5.8 5.8 4.2 5.9 8.5 4.8 7.0 5.4 4.5 4.9 6.7 5.2 5.4 5.5 5.4 8.6 7.3 4.9 7.1 5.7 6.0 10.9 6.9 7.6 6.0 6.1 5.3 5.9 7.1 5.2 6.1 5.8 6.7 7.1 7.9 5.4 39.6 8.8 20.9 7.3 4.8 9.5 6.0 8.3 11.5 8.1 16.5 12.5 7.9 12.4 5.0 20.8 9.5 21.3 9.8 6.9 8.5 18.0 19.6 7.1 11.9 13.4 9.2 12.7 17.5 6.3 10.7 17.6 20.4 11.2 24.2 14.4 8.3 9.6 10.4 16.9 6.2 18.5 12.2 5.3 4.5 9.5 21.7 14.0 11.8 14.6 16.6 12.1 12.4 4.6 17.8 16.7 11.4 0.0 4.8 7.0 13.0 18.1 12.2 15.8 10.7 4.5 12.2 6.3 10.4 12.7 13.6 9.3 12.8 8.4 24.6 21.0 3.8 9.3 18.8 16.5 7.5 14.1 9.6 9.7 12.4 10.8 9.4 7.7 6.4 11.5 12.0 10.1 6.8 7.9 12.5 8.1 7.3 5.0 5.6 14.2 10.8 10.4 6.7 5.2 7.3 4.9 7.6 8.8 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favourable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favourable (7.41e-4)" 16.5 18.9 16.8 42.2 22.7 29.9 16.7 32.4 27.7 18.0 32.5 19.7 18.6 48.2 22.4 18.6 23.7 20.5 26.8 11.4 16.2 13.9 25.0 22.1 22.2 22.4 17.6 19.4 21.1 33.0 19.5 18.9 16.6 17.9 20.3 15.2 16.9 70.8 20.6 26.2 25.6 41.1 15.2 14.3 30.9 39.2 28.6 18.5 23.6 19.7 19.2 22.3 18.9 18.9 4.7 7.1 10.8 19.3 4.0 8.5 6.9 15.7 12.7 7.8 13.2 7.8 6.7 20.1 15.0 9.0 10.3 8.6 16.0 22.6 13.5 10.2 9.0 13.8 8.0 12.4 4.9 13.7 14.1 15.6 12.8 12.0 14.7 15.8 24.5 9.7 10.7 10.4 5.1 11.2 16.8 17.1 6.9 15.2 26.8 40.9 13.9 23.3 22.2 9.0 12.0 8.3 12.9 13.4 14.5 8.7 11.1 10.4 17.8 13.6 18.4 14.4 8.4 14.6 20.0 27.8 18.6 15.0 16.2 19.4 13.1 2.6 9.0 10.8 8.5 8.9 7.4 4.7 5.6 5.7 6.0 4.0 3.2 4.7 6.7 4.0 19.3 7.1 5.0 6.9 16.8 22.7 32.4 27.7 16.2 13.9 17.6 19.4 17.9 18.5 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574587 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 28.7;gallbladder: 13.4;intestine: 25.1;kidney: 13.3;stomach 1: 7.2" "Cell line enhanced" "Detected in some" "A549: 22.6;CACO-2: 6.2;EFO-21: 12.3;K-562: 5.2" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001220 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA001220: AB_1078933" "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 0.8 0.6 8.4 0.7 9.6 1.2 0.8 1.4 12.3 1.4 11.3 25.8 0.0 24.2 1.3 2.3 0.8 2.2 13.4 0.5 12.1 8.3 13.3 1.6 1.5 0.9 14.0 2.6 1.2 2.9 0.6 0.5 1.3 12.4 1.2 2.8 0.3 1.0 1.9 1.9 2.1 25.1 0.7 28.7 0.7 7.2 2.5 7.8 0.0 0.6 0.0 0.4 1.0 0.7 2.3 2.8 2.3 0.7 0.3 0.8 0.0 0.1 22.6 0.4 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.2 3.1 0.3 12.3 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.3 0.2 4.1 0.5 0.1 0.3 0.2 0.0 0.1 0.1 0.0 5.2 0.6 0.0 0.1 0.3 0.8 3.2 0.3 0.2 0.1 0.6 0.9 0.1 0.3 1.5 0.0 0.4 0.2 0.1 0.1 0.6 0.2 0.1 0.2 0.0 2.0 1.2 0.3 0.1 0.1 0.2 0.9 0.7 0.1 0.4 0.5 0.7 1.8 0.7 0.8 0.2 2.3 0.5 0.8 2.3 0.3 0.3 2.8 0.1 0.0 8.4 9.6 1.4 10.3 12.1 8.3 14.0 2.6 12.4 7.8 GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765711 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" 8600 Cytosol "Golgi apparatus" "HPA007094: AB_1078939, HPA016960: AB_1849430" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "prognostic unfavourable (1.55e-6)" "unprognostic (3.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.77e-1)" "prognostic unfavourable (1.62e-5)" 6.4 3.3 3.8 6.2 4.4 3.6 14.2 4.6 5.1 4.7 9.3 3.7 3.5 15.9 4.7 5.0 9.0 4.8 3.8 7.2 3.6 3.6 12.3 31.6 4.7 11.7 4.3 3.8 5.2 16.0 1.9 2.6 4.6 3.2 4.7 1.3 3.6 14.9 4.7 5.4 6.2 17.3 3.7 4.0 7.2 5.3 5.7 3.3 7.6 3.3 5.1 4.8 3.6 5.0 10.6 36.7 20.7 30.2 5.7 9.4 14.6 8.0 30.3 1.8 8.5 2.7 6.8 7.1 6.5 5.4 6.7 6.3 16.8 1.6 12.5 8.2 3.4 4.7 2.0 1.9 0.7 5.4 19.0 7.8 11.5 28.1 9.2 5.2 17.3 6.0 2.6 3.3 1.4 15.6 6.2 7.7 4.1 34.4 14.4 19.7 2.1 15.7 17.3 21.1 20.8 3.7 3.3 4.1 11.4 5.6 14.4 14.2 11.7 8.6 13.7 10.0 9.6 9.5 5.7 19.5 4.8 3.2 11.2 12.2 7.7 2.6 30.2 8.3 9.4 25.5 8.5 10.6 7.8 8.6 27.2 6.8 4.2 6.2 20.7 5.7 20.2 36.7 8.7 14.6 3.8 4.4 4.6 5.1 3.6 3.6 4.3 3.8 3.2 3.3 GALK2 GK2 ENSG00000156958 "Galactokinase 2" Q01415 15 49155656-49367869 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043564, HPA048267" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA043564: AB_2678557, HPA048267: " "unprognostic (2.27e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "prognostic favourable (7.31e-4)" "unprognostic (3.04e-1)" "unprognostic (9.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-1)" "unprognostic (2.30e-1)" "unprognostic (8.67e-3)" "unprognostic (2.25e-2)" "unprognostic (2.43e-1)" "prognostic favourable (1.88e-5)" "unprognostic (2.33e-1)" "unprognostic (9.79e-2)" "unprognostic (2.13e-2)" "unprognostic (1.93e-1)" 12.7 24.9 10.2 9.2 15.3 6.5 12.4 15.7 15.3 14.7 16.3 15.3 25.6 21.5 16.0 9.9 11.5 13.5 9.9 14.2 11.3 10.3 32.3 28.4 12.7 8.0 16.2 9.4 11.5 18.5 19.4 34.2 10.8 15.3 11.1 17.9 13.2 12.2 16.3 12.5 11.6 17.9 11.8 13.9 12.8 13.9 9.2 14.8 14.6 16.7 10.9 11.5 10.3 11.6 9.6 10.4 24.2 11.3 12.8 23.1 8.7 6.2 7.3 3.4 4.5 8.7 13.6 9.9 6.5 8.7 6.5 7.7 9.3 6.6 2.0 5.2 6.8 9.1 13.4 9.3 9.2 11.2 3.9 11.7 7.0 7.8 9.5 8.0 3.7 7.0 17.1 6.9 17.3 13.1 11.6 11.4 7.0 6.7 5.8 6.4 1.4 7.0 7.1 4.1 30.3 12.0 5.9 4.1 2.7 7.2 15.0 12.3 7.4 7.8 7.2 6.4 4.4 25.9 6.1 9.4 32.3 3.8 9.9 30.7 8.7 24.2 10.6 18.6 12.8 11.3 13.6 9.6 13.1 12.6 10.4 6.7 10.5 10.7 5.4 12.8 10.8 9.2 23.1 8.7 10.2 15.3 15.7 15.3 11.3 10.3 16.2 9.4 15.3 14.8 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" 1600000 "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 15.0 14.2 11.3 11.4 16.0 9.7 24.2 14.3 12.3 15.1 18.7 11.3 8.3 18.9 10.3 13.7 31.8 8.9 13.0 18.4 15.3 9.7 12.9 21.8 12.0 27.4 14.9 13.3 10.5 22.2 4.6 15.0 22.9 12.5 11.7 18.7 15.7 28.3 8.4 19.9 27.6 24.7 15.8 13.7 17.9 11.9 9.8 12.6 13.8 13.5 16.0 17.3 32.3 19.3 6.2 6.7 11.1 9.1 6.6 5.8 2.0 7.7 8.5 10.1 9.3 20.2 19.2 13.4 8.2 8.8 7.6 7.0 5.1 15.3 9.2 8.8 8.8 6.0 5.0 15.7 12.2 10.8 4.6 11.7 16.7 11.7 10.1 25.4 15.7 13.0 15.0 11.9 13.2 82.2 3.5 12.3 29.6 6.2 7.4 9.7 10.4 4.1 9.3 13.3 4.4 31.4 36.4 5.5 10.8 14.6 10.7 8.6 8.2 20.0 28.5 14.1 5.7 9.2 9.0 17.7 8.4 17.7 9.9 17.4 7.3 8.4 5.4 11.1 5.1 6.7 5.8 6.2 3.6 4.7 6.1 3.8 3.4 4.9 6.4 6.6 9.1 6.7 3.6 2.0 11.3 16.0 14.3 12.3 15.3 9.7 14.9 13.3 12.5 12.6 GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 43.7" "Cell line enhanced" "Detected in many" "TIME: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" 830000 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favourable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavourable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" 9.5 13.5 8.4 15.4 9.1 10.1 8.7 3.2 6.2 15.9 10.6 14.4 1.0 8.8 4.9 11.5 5.9 9.2 17.8 7.7 6.9 7.5 6.8 3.4 10.1 11.5 7.2 5.2 43.7 9.2 14.1 9.7 5.2 10.1 8.3 9.4 31.6 11.6 2.4 5.6 4.0 12.4 14.1 7.7 16.7 13.8 4.3 9.2 5.6 10.6 4.2 9.3 7.5 10.0 4.7 3.1 5.7 3.8 3.9 7.5 2.1 7.4 25.4 6.2 5.4 13.2 11.8 4.8 21.5 12.0 8.6 8.2 3.5 17.1 4.8 15.2 36.1 1.3 2.8 16.8 7.9 12.6 2.0 13.3 4.8 4.8 10.2 2.8 13.0 14.6 3.9 6.9 10.3 16.4 3.0 15.4 14.6 7.7 0.3 2.0 2.4 5.2 1.5 3.3 4.8 11.9 5.1 0.8 2.0 9.5 35.6 2.8 13.8 2.2 48.2 20.9 5.0 5.1 22.8 4.4 4.3 2.6 13.7 5.7 6.3 3.4 2.7 5.3 7.5 3.6 6.6 4.5 4.3 4.8 3.1 4.7 1.9 5.3 5.7 3.9 3.8 2.7 3.5 2.1 8.4 9.1 3.2 6.2 6.9 7.5 7.2 5.2 10.1 9.2 GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122347 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 82.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039330 Uncertain "HPA039330: AB_10795249" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (4.98e-2)" "unprognostic (3.48e-2)" "prognostic unfavourable (9.54e-4)" "unprognostic (1.76e-1)" "unprognostic (9.10e-3)" "unprognostic (1.56e-3)" "unprognostic (1.38e-1)" "unprognostic (3.65e-1)" "unprognostic (3.82e-2)" "unprognostic (1.64e-1)" "prognostic favourable (2.24e-6)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (9.51e-2)" 10.7 9.4 11.1 5.1 18.7 3.8 10.4 20.8 21.8 9.1 7.5 11.4 7.1 5.1 9.6 9.2 9.8 8.3 9.3 9.2 11.4 9.3 82.0 7.1 9.6 4.9 7.0 13.4 10.6 29.7 19.3 10.5 15.9 34.1 12.0 6.5 21.7 7.8 9.8 8.8 8.3 6.9 9.5 6.5 8.5 7.6 7.3 4.4 4.6 12.5 5.6 6.4 9.4 8.1 6.3 8.3 8.2 12.5 15.7 19.3 8.7 10.5 9.4 14.0 15.6 32.5 32.1 14.4 8.4 9.6 7.1 6.7 7.6 11.1 0.0 22.0 13.6 5.0 6.6 11.9 8.8 8.7 9.8 2.1 8.6 6.7 10.7 9.4 11.2 28.2 15.4 5.9 5.0 12.8 10.6 0.1 17.7 9.1 8.1 8.6 11.5 7.6 0.0 6.1 0.3 23.4 16.3 12.5 16.6 14.0 6.8 11.3 10.1 8.2 11.5 9.6 3.4 12.0 9.2 3.1 4.0 0.1 19.9 9.2 32.6 5.8 8.3 8.2 19.3 9.4 19.0 6.3 10.7 17.7 8.3 3.8 9.2 14.0 4.4 15.7 12.5 2.5 7.9 8.7 11.1 18.7 20.8 21.8 11.4 9.3 7.0 13.4 34.1 4.4 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807699-98850081 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 34.7" "Cell line enriched" "Detected in many" 4 "U-2197: 58.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 17.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048292 Enhanced "Intracellular and membrane" 15000 "HPA048292: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favourable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 7.5 1.7 1.0 9.5 2.3 0.6 3.7 17.7 1.6 4.0 29.6 1.7 7.4 14.6 1.8 34.7 15.2 3.2 20.5 1.1 1.4 1.6 2.9 0.4 13.8 1.1 3.3 1.0 1.0 9.2 4.0 3.1 1.0 2.7 4.2 24.8 4.0 15.2 6.6 1.1 2.6 22.4 15.4 1.3 1.5 23.5 3.4 1.1 2.8 9.3 8.1 23.9 9.0 3.4 0.8 0.4 1.6 0.0 2.2 2.5 0.4 1.8 1.4 1.2 4.8 3.7 2.9 0.0 0.5 0.7 0.7 1.7 0.3 7.7 0.0 1.8 0.3 13.5 1.0 0.4 0.6 9.1 0.6 0.8 0.1 0.0 0.1 0.5 0.2 1.4 0.3 2.3 0.0 0.8 10.3 0.0 0.2 4.8 0.9 1.6 6.0 2.0 2.2 0.1 0.0 0.8 2.7 4.5 0.4 0.2 11.0 1.0 1.6 1.6 1.5 0.0 0.1 58.4 0.0 0.7 1.6 0.8 13.6 0.0 0.3 0.0 0.0 1.6 1.4 0.0 2.5 0.1 1.9 0.8 0.2 0.8 2.3 1.5 0.1 2.2 0.0 0.4 0.1 0.4 1.0 2.3 17.7 1.6 1.4 1.6 3.3 1.0 2.7 1.1 GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871913-154453849 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell line enhanced" "Detected in some" "SH-SY5Y: 27.7;U-251 MG: 7.2;WM-115: 20.7" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "eosinophil: 2.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved "HPA060775: " "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" 3.0 7.7 8.5 0.7 6.2 0.6 1.4 39.0 29.1 3.1 0.9 7.9 0.6 0.7 3.1 2.3 0.7 1.0 1.1 0.6 7.8 8.9 0.6 0.4 3.4 0.4 8.3 3.1 1.1 1.0 0.5 3.1 1.0 10.5 3.6 1.0 1.1 10.9 2.6 1.7 0.8 0.8 2.0 10.4 0.5 1.1 1.3 4.3 0.0 0.4 0.0 0.5 1.5 0.2 0.2 0.6 2.2 0.9 0.2 0.8 0.0 0.0 3.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.7 0.0 3.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.1 4.6 4.3 0.0 0.2 0.6 0.0 0.0 4.7 27.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.2 0.3 0.0 0.0 4.5 0.0 20.7 0.0 0.9 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.1 0.2 0.0 0.6 0.4 0.0 8.5 6.2 39.0 7.4 7.8 8.9 8.3 3.1 10.5 4.3 GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 42.7" "Cell line enhanced" "Detected in many" "A549: 12.9;RPMI-8226: 14.9;RPTEC TERT1: 22.0;RT4: 16.3" "Cancer enriched" "Detected in many" 7 "renal cancer: 45.9" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "neutrophil: 10.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 10.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030138 Approved "Nucleoplasm,Golgi apparatus" 9400 "Golgi apparatus" Nucleoplasm "HPA030138: " "unprognostic (5.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (2.82e-3)" "unprognostic (3.85e-2)" "unprognostic (2.10e-2)" "unprognostic (3.32e-1)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (5.18e-3)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (9.51e-3)" 1.2 1.5 1.5 0.9 3.7 4.3 1.1 1.8 9.6 1.4 0.6 1.8 0.3 0.6 0.6 1.0 10.2 1.1 3.7 0.4 1.6 1.5 42.7 1.2 0.6 2.6 1.2 2.3 0.9 2.7 7.6 5.7 0.2 0.9 1.7 0.2 2.1 1.7 0.2 0.4 1.9 3.1 0.7 0.8 1.8 0.6 1.6 0.3 0.1 1.1 1.0 4.2 2.0 1.4 1.4 0.0 10.6 0.0 0.0 0.0 0.1 10.9 12.9 0.0 0.0 0.0 0.0 0.0 3.6 1.9 2.4 0.3 0.0 0.0 10.2 3.7 0.2 0.0 0.4 0.5 0.4 0.3 1.3 5.7 0.0 0.0 0.0 8.2 0.0 0.0 2.3 0.0 8.5 0.0 0.0 9.1 0.0 5.0 0.0 0.0 6.1 0.0 7.1 0.0 14.9 22.0 16.3 12.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.2 0.9 2.8 0.0 0.0 5.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.1 1.5 3.7 1.8 9.6 1.6 1.5 1.2 2.3 0.9 0.3 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174649-16231992 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 66.7;brain: 52.3" "Group enriched" "Detected in some" 5 "ASC diff: 43.8;ASC TERT1: 43.2;HSkMC: 32.9" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebellum: 10.7;pons and medulla: 6.7" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" 25000 "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 66.7 5.3 7.6 2.6 17.4 1.1 22.8 2.3 31.5 3.9 8.6 28.1 1.1 2.8 3.5 3.3 11.4 5.3 5.2 7.3 14.8 6.6 8.3 2.8 3.1 3.4 38.9 8.4 8.4 3.2 1.6 1.0 35.5 24.8 4.9 3.8 1.3 8.0 4.1 17.3 11.6 5.3 10.5 52.3 12.8 4.6 8.1 19.9 0.0 6.3 1.6 1.5 16.6 23.5 0.6 0.9 0.9 0.3 0.3 0.4 0.3 0.0 0.0 0.0 0.0 43.8 43.2 0.0 0.9 0.7 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 32.9 0.0 0.4 0.5 0.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 7.7 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.2 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.0 0.6 0.4 0.2 0.9 0.3 0.3 0.9 0.3 0.3 7.6 17.4 2.3 13.6 14.8 6.6 38.9 8.4 24.8 19.9 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 7.7;ASC diff: 10.2;hTEC/SVTERT24-B: 14.4;SCLC-21H: 7.6;U-2 OS: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059136 Approved Approved Nucleoplasm 250000 Nucleoplasm "HPA059136: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favourable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 13.6 15.5 20.0 2.9 17.9 0.8 14.5 16.1 21.7 7.8 4.1 5.0 4.0 3.2 6.4 6.0 5.1 6.5 4.8 27.6 18.3 27.2 5.6 3.0 4.2 4.2 6.6 25.2 2.8 5.6 4.0 4.1 1.2 13.0 4.6 3.4 1.7 28.9 6.6 5.3 7.0 5.0 11.3 8.7 14.3 2.4 3.3 3.3 0.0 3.5 6.3 2.2 5.0 3.8 0.5 0.2 1.3 0.5 0.3 0.3 0.2 0.0 0.7 7.7 0.2 10.2 4.6 0.0 1.1 0.0 1.4 1.9 0.4 0.0 0.0 0.2 1.2 0.0 2.5 0.0 0.2 0.1 5.3 0.0 0.1 0.3 0.1 0.0 0.5 0.5 0.0 14.4 0.0 0.8 0.0 0.0 2.4 0.4 0.0 0.0 1.4 0.1 0.0 4.0 0.0 0.5 0.0 7.6 2.5 1.7 0.3 0.0 0.2 0.0 0.1 1.6 17.3 2.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.5 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.0 0.5 0.3 0.2 1.3 0.3 0.1 0.2 0.1 0.2 20.0 17.9 16.1 16.2 18.3 27.2 6.6 25.2 13.0 3.3 GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132169-71713600 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.9" "Cell line enhanced" "Detected in some" "AF22: 9.5;NTERA-2: 7.2;RPMI-8226: 7.9;SK-BR-3: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Uncertain "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: AB_1858787, HPA047986: " "unprognostic (2.79e-2)" "unprognostic (6.83e-2)" "unprognostic (5.54e-2)" "unprognostic (3.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (6.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.00e-1)" "prognostic favourable (4.60e-4)" "unprognostic (2.00e-1)" "unprognostic (4.73e-1)" "unprognostic (1.96e-2)" "unprognostic (9.63e-3)" "prognostic favourable (3.91e-4)" "unprognostic (1.92e-1)" "unprognostic (7.94e-3)" 1.8 7.8 8.2 2.1 13.9 0.5 1.2 25.7 42.9 2.3 4.9 1.7 1.9 0.8 7.9 4.6 8.9 4.4 2.7 19.4 13.2 4.6 2.3 0.6 3.5 0.5 2.1 12.0 22.3 9.4 0.6 4.1 0.7 4.5 9.1 1.4 1.2 1.7 8.3 1.9 0.8 1.5 12.3 1.2 3.3 1.1 3.8 0.8 0.3 9.4 0.0 1.8 10.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 7.9 0.0 0.0 0.5 0.0 0.0 30.4 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 13.9 25.7 22.5 13.2 4.6 2.1 12.0 4.5 0.8 GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270876-11622005 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 18.5;HaCaT: 23.8;HBEC3-KT: 16.6;PC-3: 16.7;RPMI-8226: 17.4;SK-BR-3: 21.7;U-87 MG: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 17 "gdT-cell: 1.7" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012955 Approved Approved Mitochondria 200000 Mitochondria "HPA012955: AB_1849460" "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" "unprognostic (3.69e-2)" "prognostic unfavourable (1.29e-4)" "unprognostic (7.37e-2)" "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (2.05e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-1)" "unprognostic (2.66e-3)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" 18.6 6.0 15.5 4.9 13.5 0.8 9.1 21.3 16.2 7.0 13.3 5.8 8.3 3.9 15.0 6.4 7.8 7.6 12.6 21.9 13.1 7.0 19.7 6.6 31.2 5.8 10.0 12.1 3.8 9.5 9.1 4.3 26.6 12.8 8.2 4.3 7.1 10.4 11.5 6.1 7.6 4.9 15.0 6.5 4.0 4.1 13.3 8.4 0.7 39.2 5.6 4.2 10.3 9.1 0.0 0.0 0.0 0.0 0.0 1.7 0.3 18.5 6.8 0.9 4.2 0.0 0.0 0.1 2.0 5.1 0.2 0.0 0.7 2.4 0.0 1.4 0.0 23.8 4.5 16.6 0.0 0.0 6.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 6.9 0.0 6.3 0.0 0.0 0.0 0.9 4.5 0.2 0.0 0.7 16.7 0.0 0.0 17.4 12.8 2.3 0.3 1.9 3.4 21.7 0.1 4.5 0.0 0.0 0.3 3.8 0.1 0.1 0.0 0.0 0.0 15.8 0.0 4.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 15.5 13.5 21.3 16.2 13.1 7.0 10.0 12.1 12.8 8.4 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282124 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 140.3" "Cell line enhanced" "Detected in all" "WM-115: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" 11000000 "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavourable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavourable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavourable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 19.5 25.6 11.1 19.6 10.1 6.9 20.4 7.7 12.5 11.7 12.7 9.1 10.5 11.3 13.7 11.5 11.5 13.2 17.0 13.9 12.5 8.5 17.5 140.3 13.2 20.4 8.4 9.0 24.8 35.9 4.3 7.3 16.6 12.6 10.8 7.5 10.5 11.1 9.6 42.2 8.4 11.3 14.6 13.6 9.5 18.0 12.7 8.2 28.4 10.7 10.7 7.0 14.9 13.1 6.7 13.5 3.5 10.1 2.7 5.3 6.3 15.9 21.3 12.6 14.9 24.2 20.7 26.0 30.3 18.8 12.3 11.8 9.2 30.4 4.0 22.5 15.9 31.2 8.3 25.4 10.4 40.3 10.8 12.3 47.7 10.2 13.2 4.7 24.2 29.6 12.6 16.4 6.6 14.4 15.3 6.2 13.6 4.4 24.3 4.7 17.2 20.4 27.1 18.0 12.4 12.1 19.0 4.0 14.9 30.7 1.6 18.4 9.7 8.8 34.1 12.1 23.3 27.2 24.0 20.7 11.9 9.0 31.2 9.4 89.5 1.1 10.1 3.5 4.7 9.6 3.6 3.8 2.9 4.7 7.9 6.7 2.8 5.3 3.2 2.7 9.6 13.5 3.4 6.3 11.1 10.1 7.7 11.8 12.5 8.5 8.4 9.0 12.6 8.2 GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747591-165794682 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.5;HaCaT: 37.5;HBEC3-KT: 25.3;hTCEpi: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007613 Enhanced Supported "Golgi apparatus" 88000 "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavourable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" 1.5 1.7 1.5 6.3 1.7 14.6 12.0 2.2 1.7 11.9 21.3 3.6 6.5 15.5 2.4 8.8 23.4 15.7 26.4 0.9 1.9 2.1 15.1 2.1 15.3 0.6 4.2 1.2 6.4 31.2 3.0 23.0 7.0 4.2 13.8 21.2 1.7 35.7 5.4 0.7 6.7 37.4 0.5 4.8 23.3 28.9 17.6 3.3 1.5 37.6 15.1 20.8 11.7 9.3 3.3 7.5 21.1 5.7 5.8 5.3 2.3 20.1 0.0 0.1 0.0 0.0 0.8 13.4 4.4 1.7 1.7 4.5 12.4 32.5 0.1 0.0 0.0 37.5 0.0 25.3 3.8 0.2 3.6 0.0 3.7 0.1 0.1 3.7 0.1 0.1 35.7 0.0 9.5 0.0 0.0 16.7 1.4 14.4 0.1 1.5 0.0 2.0 0.0 0.0 0.6 6.7 16.9 2.0 0.0 0.0 18.2 4.1 8.1 0.1 0.1 0.0 0.3 0.0 0.0 8.6 4.2 0.3 0.0 3.9 0.1 21.1 3.1 13.8 5.3 4.5 4.1 3.3 1.7 3.3 5.3 3.1 0.6 1.9 10.5 5.8 5.7 7.5 2.9 2.3 1.5 1.7 2.2 1.7 1.9 2.1 4.2 1.2 4.2 3.3 GALNT4 GalNAc-T4 ENSG00000257594 "Polypeptide N-acetylgalactosaminyltransferase 4" Q8N4A0 12 89519408-89524806 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 18.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA076116 Approved "Golgi apparatus" 270000 "Golgi apparatus" "HPA076116: " "unprognostic (2.96e-2)" "unprognostic (7.65e-3)" "unprognostic (8.76e-2)" "unprognostic (3.94e-5)" "unprognostic (3.50e-1)" "unprognostic (4.87e-2)" "unprognostic (2.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.24e-1)" "unprognostic (5.81e-6)" "unprognostic (2.34e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-2)" "unprognostic (2.52e-1)" 5.0 2.4 4.0 5.8 3.2 3.9 2.6 1.4 3.4 11.1 14.3 3.7 2.7 11.1 9.5 1.9 3.7 7.7 15.8 2.9 1.9 1.7 8.3 5.6 3.2 1.7 4.4 1.1 4.3 8.6 1.1 5.9 2.9 3.7 2.9 11.4 3.3 22.6 1.2 1.1 1.8 20.8 2.0 2.6 7.5 21.0 1.4 3.7 0.2 2.7 2.0 8.2 4.1 2.8 2.8 3.4 5.9 7.5 7.3 5.8 2.7 2.5 7.7 2.7 14.9 5.5 7.9 1.9 6.2 2.9 2.5 2.7 3.0 4.8 0.0 1.5 4.6 4.0 0.8 4.1 4.3 6.5 1.7 3.1 1.4 2.3 2.6 2.8 7.0 3.6 1.8 5.2 2.3 8.1 1.9 1.4 3.9 1.9 0.2 5.5 1.8 18.5 0.6 0.5 1.2 7.6 8.0 0.1 1.2 0.8 4.2 5.7 8.2 2.8 7.5 5.3 1.9 3.2 2.0 1.3 2.2 1.2 2.7 1.4 3.0 5.9 5.2 2.4 3.2 7.4 5.8 1.9 1.8 2.4 3.4 2.8 2.6 2.3 5.0 7.3 7.5 1.2 1.9 2.7 4.0 3.2 1.4 3.4 1.9 1.7 4.4 1.1 3.7 3.7 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257598-157314211 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell line enhanced" "Detected in some" "A-431: 23.1;BJ: 15.2;BJ hTERT+: 27.2;fHDF/TERT166: 31.7;HaCaT: 27.1;K-562: 15.7;LHCN-M2: 27.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "cerebellum: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" 630000 "Nucleoli, Golgi apparatus, Cytosol" Vesicles "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.4 0.2 0.2 1.5 0.2 0.5 1.1 28.2 0.2 7.5 12.0 0.7 0.0 2.3 0.5 0.5 9.0 0.2 17.1 0.9 0.4 0.2 0.3 0.2 15.5 0.0 0.2 0.0 0.3 1.5 0.0 6.8 0.1 4.4 1.6 16.1 0.3 18.9 0.2 0.2 0.5 8.4 0.8 0.3 0.3 15.2 0.5 0.0 0.1 0.3 12.2 11.7 2.3 6.6 0.2 0.1 0.2 0.1 0.1 0.5 0.0 23.1 2.5 0.0 0.0 1.0 8.1 0.0 15.2 27.2 0.2 0.6 1.0 13.4 0.0 0.0 31.7 27.1 0.4 5.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.1 0.0 0.5 0.0 15.7 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.2 28.2 0.2 0.4 0.2 0.2 0.0 4.4 0.0 GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 35.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 33.6;CACO-2: 33.2;SK-BR-3: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 23.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 2900000 "Nucleoplasm, Golgi apparatus" "HPA011762: AB_1849450, HPA017086: AB_1849452" "unprognostic (2.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.26e-2)" "prognostic favourable (9.85e-4)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-3)" "unprognostic (2.05e-1)" "unprognostic (2.27e-2)" "prognostic favourable (5.40e-4)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (7.13e-4)" "unprognostic (5.65e-3)" "unprognostic (3.18e-1)" "unprognostic (2.16e-2)" "unprognostic (1.18e-2)" 3.1 1.8 4.0 4.1 9.5 4.4 10.6 1.0 5.1 19.5 13.4 15.4 0.5 11.8 0.9 14.4 2.8 3.7 6.8 0.8 7.1 3.6 2.5 0.8 4.1 4.0 14.4 3.6 1.4 6.3 0.4 1.6 9.9 5.8 1.3 3.9 0.9 23.8 6.3 0.6 5.5 16.9 0.8 8.3 5.5 35.4 0.8 9.7 6.6 1.8 2.3 6.6 2.2 2.2 2.9 3.7 23.8 6.5 10.8 3.4 2.8 11.5 1.2 0.2 0.0 0.0 0.1 18.5 19.4 33.6 8.3 5.6 33.2 6.1 0.1 1.8 10.9 11.1 0.6 8.4 5.3 2.6 1.2 7.4 0.2 0.2 0.3 3.9 26.1 0.7 7.8 7.4 7.1 20.4 1.6 0.3 0.0 22.6 12.5 2.9 1.6 21.0 0.0 0.0 3.3 6.5 0.8 0.1 7.5 0.1 33.9 0.0 18.8 1.7 23.9 0.0 4.2 0.0 0.0 0.6 0.1 1.0 2.3 8.7 0.1 4.5 4.4 23.8 3.4 3.7 1.4 0.8 1.7 2.6 3.7 2.9 2.7 2.3 0.8 10.8 6.5 3.1 1.1 2.8 4.0 9.5 1.0 5.1 7.1 3.6 14.4 3.6 5.8 9.7 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" "Q9NY28, P17658" 12 4720341-4851927 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Glycosyltransferase, Ion channel, Potassium channel, Transferase, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 12.7;intestine: 33.2;testis: 18.5" "Group enriched" "Detected in some" 4 "Karpas-707: 26.3;NTERA-2: 9.3;U-266/84: 7.5" "Cancer enhanced" "Detected in some" "testis cancer: 2.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012638, HPA073461" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: " "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 1.1 2.2 5.3 2.2 6.5 0.5 3.1 1.4 12.7 1.0 15.5 9.4 0.0 7.2 0.9 0.4 0.7 1.2 1.1 3.7 8.0 1.7 1.2 0.8 0.9 1.0 5.7 9.6 1.6 0.9 0.2 3.7 0.5 6.0 1.1 33.2 0.1 1.0 0.9 0.7 0.9 14.7 2.1 3.5 1.2 1.3 18.5 11.5 0.0 0.8 0.5 0.9 1.2 0.9 1.0 0.7 0.1 0.1 0.9 3.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 26.3 0.0 0.0 0.2 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 7.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.4 0.3 0.7 1.2 0.0 1.0 0.0 0.1 0.1 0.9 0.0 0.7 3.0 0.0 5.3 6.5 1.4 12.7 8.0 1.7 5.7 9.6 6.0 11.5 GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329349 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 52.4" "Cell line enriched" "Detected in some" 5 "U-87 MG: 26.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 2.6;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles Vesicles "HPA075016: " "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-3)" "unprognostic (2.85e-1)" "unprognostic (6.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" "unprognostic (5.69e-2)" 2.6 2.2 9.3 1.0 6.7 0.6 0.5 52.4 27.9 1.1 0.8 0.8 0.0 1.1 1.8 7.7 0.5 1.9 0.7 0.6 12.9 6.8 3.2 0.5 0.9 1.3 4.3 10.8 1.3 0.4 1.9 2.7 0.5 6.9 1.0 0.6 0.3 1.2 1.7 0.5 0.9 1.0 0.6 1.7 1.2 0.7 0.9 1.1 0.0 6.1 0.0 0.4 0.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 26.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 2.6 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.3 6.7 52.4 20.2 12.9 6.8 4.3 10.8 6.9 1.1 GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.5;lymphoid tissue: 7.3;testis: 6.4" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;SCLC-21H: 2.4;SK-MEL-30: 1.9;U-266/70: 2.8;WM-115: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 4.5;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031019 Uncertain "Intracellular and membrane" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" 0.2 0.7 3.9 1.2 8.3 1.1 0.7 1.0 9.5 3.3 1.0 0.6 0.0 0.7 0.3 0.3 0.2 0.3 0.5 0.5 3.6 4.1 0.3 0.5 0.5 1.3 7.6 2.4 0.1 0.5 0.1 0.0 0.1 1.8 2.2 0.7 1.3 0.3 0.2 0.5 0.6 1.2 0.3 0.5 7.3 2.9 6.4 1.2 0.0 0.5 1.1 0.4 0.5 0.6 4.5 0.5 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.5 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.7 1.2 0.0 1.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.7 2.3 0.2 1.1 0.3 0.6 1.4 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.0 0.0 0.5 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.3 0.1 1.7 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.3 1.0 5.9 3.6 4.1 7.6 2.4 1.8 1.2 GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol 120000 Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favourable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favourable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" 6.3 16.1 8.0 13.8 12.5 7.4 6.6 9.3 7.3 8.5 19.4 5.8 12.4 18.1 7.2 8.4 7.7 6.5 10.5 10.9 6.7 8.6 11.8 47.0 6.8 10.8 9.0 6.0 8.7 7.6 12.1 10.3 21.7 7.5 7.2 6.8 11.0 12.5 13.4 9.5 14.4 26.1 5.9 5.0 9.4 8.1 2.6 7.1 11.3 8.5 7.2 10.6 7.0 6.5 16.3 15.9 10.9 17.5 20.5 21.1 13.1 4.9 6.6 6.0 2.4 8.3 8.3 7.0 3.7 10.6 3.9 4.4 8.2 4.6 5.6 3.8 4.4 2.7 1.1 10.3 0.7 8.3 4.5 2.3 13.2 8.3 8.1 1.3 2.9 12.1 6.6 2.5 3.1 9.3 1.9 6.1 6.2 4.3 4.7 9.4 2.1 1.2 7.3 5.5 2.9 10.7 6.9 1.4 5.3 4.7 9.3 5.0 8.3 7.2 1.4 1.7 3.2 3.3 0.0 3.5 2.0 1.1 4.0 3.9 9.8 10.9 17.5 8.3 12.1 15.0 16.7 16.3 19.8 16.3 15.9 9.3 12.2 12.0 3.3 20.5 14.1 13.3 21.1 13.1 8.0 12.5 9.3 7.3 6.7 8.6 9.0 6.0 7.5 7.1 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.0;skeletal muscle: 222.2" "Cell line enhanced" "Detected in many" "Hep G2: 51.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved 38000 "HPA051806: " "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavourable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 5.1 4.6 9.1 1.5 8.7 2.2 3.2 5.1 11.4 2.3 1.4 15.1 5.1 1.3 2.0 31.3 5.3 3.8 2.6 10.8 9.2 7.7 8.0 73.0 1.5 2.0 8.7 5.2 3.8 47.0 5.4 4.9 1.6 5.9 5.6 1.1 4.5 9.1 4.7 222.2 6.0 1.4 2.1 8.8 2.1 3.2 7.7 4.5 5.6 3.3 26.7 2.8 1.9 1.7 15.7 23.0 6.9 2.6 8.0 21.6 7.7 6.2 7.1 7.6 17.2 9.6 11.7 10.4 7.5 12.5 9.7 8.8 16.0 4.5 3.3 5.3 8.9 2.7 12.0 4.6 2.6 23.8 13.7 10.2 5.9 51.2 5.7 0.2 3.5 13.0 1.6 10.3 0.0 2.1 14.5 8.0 15.8 6.4 29.8 3.5 8.6 22.6 29.9 6.8 23.8 11.4 5.8 2.5 17.9 0.5 4.3 9.2 19.8 14.2 3.6 10.7 11.1 0.6 3.4 36.3 7.0 5.6 9.9 13.5 12.2 1.6 1.2 6.9 9.9 1.6 13.9 10.6 13.7 12.2 5.4 15.7 21.6 16.1 0.8 8.0 2.6 23.0 7.5 7.7 9.1 8.7 5.1 11.4 9.2 7.7 8.7 5.2 5.9 4.5 GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Uncertain Nucleoplasm,Mitochondria,Cytosol 1300000 "Nucleoplasm, Mitochondria, Cytosol" "HPA002119: AB_1849482, HPA005779: AB_1849484" "unprognostic (3.77e-2)" "unprognostic (2.25e-2)" "unprognostic (4.51e-3)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "prognostic unfavourable (5.05e-5)" "prognostic unfavourable (9.82e-5)" "unprognostic (2.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.92e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.98e-3)" "prognostic unfavourable (3.95e-6)" "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" 24.9 24.7 16.0 20.0 22.3 14.2 22.2 14.5 20.3 16.2 20.1 20.5 13.3 18.9 21.7 15.9 28.1 19.9 14.3 19.3 16.4 14.9 19.2 33.6 18.3 24.4 21.9 14.6 21.0 30.6 21.6 22.9 23.1 21.0 16.4 26.9 19.5 18.6 16.1 33.2 17.6 19.1 23.5 17.9 21.4 21.9 47.0 21.7 40.8 20.0 19.4 32.8 21.6 17.6 18.7 19.5 9.7 20.9 27.1 21.1 13.3 30.0 14.3 21.2 23.5 15.6 16.1 23.8 19.5 16.5 22.8 24.2 27.1 25.6 40.0 11.6 13.0 15.9 44.4 30.6 33.3 21.0 26.4 60.3 17.1 17.7 21.3 33.5 15.9 14.2 21.4 26.9 39.6 21.5 70.1 25.7 20.6 14.4 35.3 22.5 46.2 16.9 29.5 39.5 56.6 18.3 16.1 22.6 20.3 27.0 21.3 25.2 27.0 21.5 15.8 15.5 18.6 13.4 20.8 25.6 35.4 43.7 16.3 39.5 22.9 5.3 15.2 9.7 17.3 20.9 21.1 18.7 16.9 17.9 19.5 14.4 17.7 17.4 7.0 27.1 17.7 14.7 20.6 13.3 16.0 22.3 14.5 20.3 16.4 14.9 21.9 14.6 21.0 21.7 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 186.3;liver: 252.2;pancreas: 286.1" "Group enriched" "Detected in some" 4 "RH-30: 55.9;RT4: 14.7;U-266/70: 34.5;U-266/84: 43.6" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 12.8;myeloid DC: 6.9;naive B-cell: 5.9;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 6 "B-cells: 12.8;dendritic cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria 620000 Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favourable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 1.8 2.5 18.5 1.6 14.7 0.6 2.9 11.4 16.2 1.5 3.1 24.9 0.3 17.8 1.3 2.2 3.0 1.7 5.0 5.5 15.2 10.3 186.3 252.2 1.2 2.1 20.6 14.3 17.6 286.1 0.7 1.2 7.8 14.5 1.7 1.7 1.5 5.5 2.1 13.5 13.9 10.8 2.7 26.1 3.5 10.0 8.0 18.4 0.7 6.6 2.5 3.1 2.2 2.0 12.8 6.9 0.3 1.5 0.1 1.5 0.8 3.4 1.7 1.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 5.7 8.8 0.3 0.0 0.6 4.4 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.2 5.1 0.7 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.6 0.1 3.1 0.0 0.1 55.9 0.4 0.9 14.7 6.5 1.1 1.8 0.1 0.3 0.7 5.8 0.0 0.0 0.1 0.0 1.7 34.5 43.6 0.2 0.4 0.1 0.3 0.0 1.1 0.3 0.3 1.5 0.0 12.8 0.0 0.3 6.9 5.9 0.0 1.5 0.0 0.1 0.6 6.8 0.0 0.8 18.5 14.7 11.4 16.2 15.2 10.3 20.6 14.3 14.5 18.4 GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489699-81762161 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.9" "Cell line enhanced" "Detected in all" "ASC diff: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Nucleoplasm,Cytosol 5900000 "Nucleoplasm, Cytosol" "HPA038073: AB_10673040, HPA038074: AB_10672403, HPA038075: AB_10674545" "unprognostic (3.10e-1)" "unprognostic (1.02e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.89e-1)" "unprognostic (9.01e-3)" "unprognostic (1.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" "unprognostic (5.68e-2)" "unprognostic (1.46e-1)" "unprognostic (5.36e-2)" "unprognostic (4.42e-1)" "unprognostic (2.83e-3)" "unprognostic (3.78e-3)" 23.1 22.4 2.2 7.8 4.2 5.6 19.2 4.2 4.6 6.4 7.7 5.2 5.2 4.1 8.4 4.9 7.5 4.9 11.5 19.7 3.6 4.3 14.0 36.3 11.3 7.5 7.9 3.4 8.2 5.7 8.2 11.6 11.4 8.4 5.7 4.5 9.9 8.0 10.1 56.9 5.9 6.3 7.2 6.1 8.0 4.5 4.6 4.1 5.4 6.5 11.2 4.5 9.6 10.0 11.6 13.6 14.5 11.4 13.0 7.2 6.1 12.0 7.3 2.4 34.6 60.9 46.3 4.4 20.0 28.6 12.0 20.4 1.4 3.1 13.5 8.8 24.6 1.4 2.0 9.2 28.3 6.3 1.1 4.2 15.1 4.5 41.9 14.1 3.7 34.1 6.9 19.3 19.9 26.6 3.2 7.8 39.0 3.5 2.3 16.8 2.4 11.1 4.4 11.0 15.8 8.5 4.1 1.2 1.6 13.0 3.8 4.1 2.7 11.7 37.0 24.9 5.8 17.4 18.5 35.7 4.1 4.9 40.5 9.5 10.1 6.3 11.4 14.5 5.6 10.4 5.4 11.0 6.0 5.9 13.6 11.6 7.0 7.2 11.0 13.0 10.8 4.5 5.0 6.1 2.2 4.2 4.2 4.6 3.6 4.3 7.9 3.4 8.4 4.1 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 81.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020460 Uncertain Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548" "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 2.9 6.0 8.9 2.4 8.8 8.1 4.2 8.3 12.3 4.5 4.7 5.2 8.0 3.5 3.0 4.0 6.3 3.9 6.0 21.5 8.6 8.4 8.1 19.1 2.3 2.1 10.1 7.4 4.0 81.6 3.5 3.7 2.2 7.4 12.2 3.5 4.3 12.0 5.0 10.3 3.2 3.2 3.1 6.3 1.1 4.4 5.9 4.3 2.8 10.7 9.3 4.3 3.3 2.2 0.3 2.5 0.8 1.3 2.3 7.1 2.8 8.7 2.3 5.9 33.6 12.2 9.9 4.1 12.6 13.3 9.6 8.2 5.1 1.0 2.7 5.9 5.6 5.1 5.9 8.9 2.2 1.2 10.7 6.1 7.3 20.1 19.9 10.8 8.0 11.6 5.4 6.3 14.0 7.8 15.6 3.2 4.5 7.7 11.3 20.0 2.5 9.4 11.9 1.2 16.1 12.1 6.9 12.2 8.3 9.8 15.9 6.7 12.8 5.3 5.9 9.7 5.3 6.4 4.3 10.7 5.2 5.7 6.7 10.1 10.1 0.2 1.3 0.8 1.5 1.2 0.6 0.3 3.4 1.0 2.4 0.1 7.1 2.9 0.6 2.3 0.8 2.5 3.3 2.8 8.9 8.8 8.3 12.3 8.6 8.4 10.1 7.4 7.4 4.3 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44144271-44198170 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 46.8" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 12.0" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 4.4;naive CD4 T-cell: 4.8" "Group enriched" "Detected in many" 17 "B-cells: 4.4;T-cells: 4.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 1.1 0.5 3.2 0.7 2.8 0.0 0.7 9.5 3.7 1.4 1.4 1.3 0.7 0.3 1.5 1.5 0.7 2.3 0.9 7.1 2.1 7.5 0.7 8.7 0.7 0.7 2.9 1.2 2.2 2.9 0.0 46.8 3.3 1.6 0.8 0.5 0.8 0.7 1.6 0.7 1.2 0.7 0.7 1.7 0.7 0.9 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.9 4.4 0.2 0.0 0.0 0.0 4.8 0.7 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.6 0.3 0.0 0.0 0.0 0.1 0.8 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.6 0.9 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.6 4.4 1.6 0.4 0.2 0.7 4.8 0.9 0.0 0.0 0.0 0.0 0.0 0.7 3.2 2.8 9.5 2.4 2.1 7.5 2.9 1.2 1.6 0.7 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1, core 2" Q02742 9 76419850-76507416 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.0;parathyroid gland: 57.8" "Cell line enhanced" "Detected in many" "HHSteC: 25.8;HSkMC: 21.9;U-2197: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 16.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "cerebellum: 8.2;olfactory region: 30.1" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" 72000 "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favourable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavourable (4.96e-4)" 5.6 1.1 1.6 7.9 3.9 2.2 8.2 10.9 2.7 5.3 24.5 0.7 3.0 23.2 5.2 1.2 2.1 1.8 4.1 3.1 2.1 1.4 1.4 1.0 4.5 9.2 1.6 2.1 0.9 2.0 57.8 1.9 3.9 1.0 4.9 4.6 0.5 9.1 1.8 0.8 1.5 32.0 2.5 1.2 7.6 18.6 1.4 0.6 2.8 16.9 1.2 6.4 2.4 3.3 9.4 4.7 16.8 6.4 4.7 1.9 1.6 2.4 0.2 0.1 0.0 3.1 14.9 3.6 10.0 4.5 8.1 5.8 2.5 0.6 1.7 1.0 7.4 2.1 5.0 4.1 9.1 1.2 0.8 4.2 0.2 0.4 25.8 3.1 1.4 21.9 1.1 7.9 8.5 7.4 0.0 1.7 8.1 3.7 1.6 5.0 4.7 0.6 2.8 5.0 0.8 9.5 4.4 1.0 0.0 1.2 1.3 0.0 0.0 2.1 3.0 5.1 3.3 18.3 4.4 2.6 0.4 0.0 10.3 5.3 1.2 4.3 2.7 16.8 1.3 6.4 0.4 1.3 1.5 1.3 4.7 9.4 0.2 1.0 0.9 4.7 5.7 2.3 1.9 1.6 1.6 3.9 10.9 2.7 2.1 1.4 1.6 2.1 1.0 0.6 GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.1" "Cell line enhanced" "Detected in many" "EFO-21: 26.2;Hep G2: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 54.8" "Low region specificity" "Detected in all" HPA026776 Approved Supported "Golgi apparatus" 560000 "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" 2.0 0.9 2.5 7.9 2.8 0.7 12.7 7.6 1.9 6.0 13.0 2.0 0.9 7.8 5.6 1.3 3.7 1.7 2.8 11.8 2.2 2.4 19.6 14.3 10.4 3.3 2.4 0.4 0.9 5.5 1.0 6.2 3.1 4.0 21.9 3.7 8.1 7.4 0.9 2.3 2.5 25.1 2.6 2.2 4.2 8.3 9.0 2.9 0.9 2.4 1.2 7.2 2.0 3.0 2.1 2.5 4.2 3.1 0.5 0.4 0.7 4.2 3.5 1.2 2.9 0.0 0.0 3.5 0.0 3.1 0.8 0.2 6.2 3.1 2.4 26.2 0.0 0.1 0.3 3.2 1.8 1.6 0.9 0.5 1.8 10.9 0.0 1.1 2.9 0.0 0.0 0.3 0.0 6.9 0.3 0.0 0.3 0.0 0.0 2.2 3.9 2.4 0.1 2.4 3.8 9.3 2.3 2.6 1.8 0.0 9.2 8.8 0.1 0.4 5.9 0.5 0.4 0.0 3.4 0.0 0.0 1.7 0.5 0.2 1.4 4.2 3.1 1.3 0.3 2.3 0.1 2.1 0.3 0.4 2.5 1.3 0.4 0.4 0.2 0.5 0.8 0.6 0.2 0.7 2.5 2.8 7.6 1.9 2.2 2.4 2.4 0.4 4.0 2.9 GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 29.6;intestine: 103.3;salivary gland: 27.4" "Cell line enriched" "Detected in some" 5 "A549: 55.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 29.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favourable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavourable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" 0.3 0.5 0.3 8.8 0.4 0.0 0.3 0.3 0.3 5.3 37.6 0.3 0.3 25.4 1.3 0.4 8.7 0.7 29.6 0.3 0.3 0.2 9.9 0.4 0.7 0.3 0.3 0.3 1.1 1.7 0.0 0.4 1.0 0.5 1.0 33.4 0.3 27.4 0.3 0.3 0.2 103.3 0.9 0.3 0.3 6.5 1.7 0.3 0.5 0.7 5.2 15.5 0.7 14.0 1.2 1.4 3.4 0.8 1.1 0.7 0.1 0.0 55.8 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.0 0.0 2.3 2.3 0.2 9.6 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 11.2 0.0 0.1 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 3.9 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.1 0.1 0.2 3.5 0.1 0.0 2.6 0.8 0.6 0.7 0.4 0.4 0.6 0.5 0.3 0.2 1.2 0.4 0.6 3.4 1.1 0.4 1.4 0.5 0.1 0.3 0.4 0.3 0.3 0.3 0.2 0.3 0.3 0.5 0.3 GCNT4 C2GNT3 ENSG00000176928 "Glucosaminyl (N-acetyl) transferase 4, core 2" Q9P109 5 75025346-75030899 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 13.6;intestine: 13.1;stomach 1: 10.4" "Cell line enriched" "Detected in some" 5 "RT4: 26.3" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 13.6" "Group enriched" "Detected in many" 54 "granulocytes: 13.6;T-cells: 11.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037431 Approved Supported "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA037431: AB_10670382" "unprognostic (1.88e-2)" "unprognostic (5.63e-2)" "unprognostic (6.05e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" "unprognostic (4.98e-2)" "unprognostic (4.11e-3)" "unprognostic (1.63e-2)" "unprognostic (3.47e-1)" "unprognostic (2.20e-2)" "unprognostic (4.49e-3)" "unprognostic (6.04e-2)" "prognostic favourable (1.93e-7)" "unprognostic (8.39e-2)" "unprognostic (1.93e-1)" "unprognostic (6.06e-2)" "unprognostic (5.82e-2)" 0.6 0.6 0.3 1.0 0.7 0.0 0.9 0.0 2.3 1.1 1.1 13.1 1.4 0.6 1.3 1.1 2.5 0.3 0.3 0.1 1.8 0.4 1.0 1.7 0.1 0.9 3.0 8.4 0.1 3.0 1.0 0.2 0.5 2.4 1.0 1.5 10.8 0.7 0.0 0.6 10.4 1.0 0.5 1.1 6.4 2.0 0.0 0.0 13.6 0.1 0.2 11.6 1.6 0.2 0.1 1.0 1.6 1.8 0.6 0.1 2.0 5.2 1.0 0.9 2.5 0.1 0.0 0.2 1.5 0.7 1.0 1.8 0.2 0.0 0.0 0.8 0.2 0.2 0.8 0.0 0.0 0.3 2.9 0.1 0.3 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.4 0.0 0.0 0.0 2.6 0.2 26.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.7 0.1 0.0 0.0 0.0 0.3 0.0 0.1 13.6 0.0 0.0 0.9 0.0 3.5 0.0 8.1 2.6 0.0 0.0 8.1 5.9 0.1 0.2 0.1 0.0 11.6 1.6 GDPGP1 C15orf58 ENSG00000183208 "GDP-D-glucose phosphorylase 1" Q6ZNW5 15 90233808-90245811 "Enzymes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA048189, HPA059841" Approved Approved Cytosol Cytosol "HPA048189: , HPA059841: " "prognostic favourable (6.32e-4)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-1)" "unprognostic (3.68e-2)" "unprognostic (4.46e-3)" "unprognostic (1.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-2)" "unprognostic (2.93e-3)" "unprognostic (8.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" 3.9 9.2 9.8 5.7 9.8 5.1 4.8 9.9 12.4 4.4 10.7 8.0 7.2 10.1 5.0 7.5 6.2 9.4 6.0 10.8 12.9 7.1 7.7 12.2 5.8 6.1 5.9 11.6 6.1 9.1 11.9 10.2 2.1 8.8 7.5 14.8 7.2 9.9 10.0 12.5 4.5 9.4 5.8 5.1 8.2 6.9 9.5 8.4 8.5 7.6 3.1 7.8 7.2 3.9 8.3 4.6 7.4 5.2 6.7 7.8 2.9 3.2 13.0 1.6 4.8 4.9 1.0 4.4 3.0 1.9 4.0 3.8 3.8 12.9 8.0 5.9 2.3 5.4 5.1 3.4 1.6 7.2 8.6 7.2 7.5 5.5 5.3 3.9 4.8 1.3 2.4 2.8 1.4 4.6 2.6 3.2 2.3 7.3 2.9 1.9 2.0 5.4 5.1 1.2 4.0 4.6 6.4 5.1 2.2 4.7 7.4 5.0 8.5 4.0 4.6 2.1 2.2 3.0 2.9 6.6 7.5 3.6 4.6 3.3 3.8 6.8 4.6 2.2 6.6 5.2 5.6 4.8 6.2 7.8 4.1 8.3 6.7 6.2 7.4 6.7 4.1 4.6 7.5 2.9 9.8 9.8 9.9 12.4 12.9 7.1 5.9 11.6 8.8 8.4 GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319769-69387254 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favourable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" 16.7 11.4 6.4 12.7 7.8 5.6 18.3 7.8 10.1 16.8 27.0 6.4 41.2 14.5 10.1 18.7 11.6 9.5 19.4 11.3 6.0 9.8 17.8 49.1 14.1 4.7 6.5 5.7 11.1 34.9 13.9 39.6 36.5 7.0 17.2 27.5 7.7 39.7 34.0 9.2 6.1 28.2 8.7 6.2 8.2 24.6 13.9 4.8 8.5 35.2 7.7 18.1 10.6 16.2 5.6 4.1 5.9 3.4 4.1 6.8 3.0 9.5 6.6 8.5 5.3 24.0 16.5 18.5 18.2 17.0 8.6 11.0 21.2 8.7 8.6 6.7 16.9 4.6 10.7 5.6 14.3 7.8 4.1 10.0 4.9 21.8 28.4 6.8 4.0 10.4 27.3 16.7 32.0 8.0 8.3 14.0 16.8 5.6 7.2 7.1 11.1 5.5 7.2 17.8 4.4 14.0 7.6 5.3 3.0 6.8 12.6 24.4 5.0 4.3 12.2 7.7 10.3 13.2 8.7 10.0 6.7 6.5 12.5 4.6 8.8 5.9 2.8 3.4 6.8 3.2 6.5 5.6 6.1 6.6 3.6 3.4 6.1 5.6 1.3 4.1 3.4 4.1 4.3 3.0 6.4 7.8 7.8 10.1 6.0 9.8 6.5 5.7 7.0 4.8 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300690-180353387 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 65.6" "Cell line enhanced" "Detected in many" "ASC diff: 24.0;ASC TERT1: 41.2;HSkMC: 26.4;hTEC/SVTERT24-B: 49.0;U-87 MG: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 7.1" "Lineage enriched" "Detected in single" 49 "T-cells: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Supported Vesicles Vesicles "HPA056892: , HPA059910: " "unprognostic (3.48e-1)" "prognostic unfavourable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavourable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavourable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.52e-3)" 65.6 3.9 4.5 15.8 5.6 0.9 11.0 17.0 9.2 10.0 9.2 9.3 5.4 2.1 9.0 16.7 5.9 15.9 14.6 16.4 7.1 3.8 2.8 2.6 11.0 3.1 6.2 6.8 17.5 11.1 3.5 2.5 6.0 8.4 7.7 3.6 2.9 4.0 8.0 6.0 4.0 5.0 10.0 17.2 1.7 6.6 6.3 7.7 0.0 5.6 5.4 3.5 14.3 14.6 0.0 0.1 0.0 0.0 0.1 7.1 0.2 0.0 5.3 4.2 5.4 24.0 41.2 0.4 0.6 0.1 0.4 0.1 0.1 0.0 0.0 0.2 4.4 0.0 2.3 0.0 0.2 0.5 0.8 0.0 2.6 0.0 10.0 0.0 0.0 26.4 0.2 49.0 0.1 7.9 0.0 0.0 21.0 0.7 0.0 0.0 9.0 2.4 0.1 0.0 0.0 0.0 0.0 0.2 0.3 8.3 0.1 0.3 0.3 0.0 3.7 13.5 2.1 8.7 9.9 0.0 0.0 0.0 85.2 0.0 0.3 0.0 0.0 0.0 1.4 0.0 7.1 0.0 0.8 2.4 0.1 0.0 0.8 1.1 0.0 0.1 0.0 0.1 0.0 0.2 4.5 5.6 17.0 9.2 7.1 3.8 6.2 6.8 8.4 7.7 GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029472 Enhanced "HPA029472: AB_10696206" "unprognostic (7.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-3)" "prognostic unfavourable (6.69e-4)" "unprognostic (4.50e-2)" "unprognostic (3.66e-2)" "unprognostic (3.77e-3)" "unprognostic (2.66e-2)" "unprognostic (8.77e-3)" "unprognostic (1.95e-2)" "unprognostic (1.99e-1)" "unprognostic (3.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-2)" 24.5 24.8 26.8 16.2 25.7 6.8 33.4 30.1 28.7 24.9 23.1 19.9 21.8 19.8 22.8 30.3 24.1 20.9 19.2 21.8 25.4 25.8 26.4 20.0 18.9 18.3 24.4 22.0 23.5 16.0 19.0 29.3 24.2 25.8 29.0 23.2 15.9 27.8 21.9 26.8 19.0 20.6 24.9 28.3 20.4 20.1 42.5 25.6 22.6 27.9 21.2 20.0 26.9 17.9 28.5 22.2 33.9 35.9 22.1 31.3 26.0 17.6 9.6 24.0 18.1 18.7 27.1 9.4 15.7 22.0 10.4 14.7 7.4 28.2 12.0 22.9 17.3 14.4 12.7 16.2 13.8 12.1 23.7 10.1 9.1 12.5 21.1 12.4 8.7 17.6 29.3 14.1 19.1 18.4 24.2 10.8 13.7 10.3 15.5 14.9 20.5 5.0 9.6 7.5 13.6 29.0 9.6 19.3 26.7 11.8 27.1 22.6 33.8 19.9 15.5 12.5 9.4 21.1 14.7 18.9 22.8 14.6 15.8 14.1 22.4 26.6 22.8 33.9 24.8 26.8 24.9 28.5 31.3 26.4 22.2 23.4 29.2 26.5 20.6 22.1 35.9 18.4 30.0 26.0 26.8 25.7 30.1 28.7 25.4 25.8 24.4 22.0 25.8 25.6 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Cell line enhanced" "Detected in many" "HDLM-2: 35.8;Karpas-707: 52.7;RPMI-8226: 51.8;RPTEC TERT1: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Approved Vesicles "Intracellular and membrane" 4600000 Vesicles "HPA045635: , HPA047534: , HPA065444: " "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favourable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.4 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.3 0.2 4.3 0.0 2.8 1.4 0.2 0.1 35.8 2.9 0.1 8.6 14.1 1.5 0.3 12.0 0.4 0.2 0.6 0.4 0.1 2.0 52.7 0.2 0.4 0.3 14.6 1.4 0.2 0.2 2.2 51.8 48.2 0.6 0.2 0.3 0.1 9.4 0.2 9.4 11.1 2.2 3.5 2.3 10.9 0.3 15.8 6.0 0.2 7.4 15.1 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 38.7;ASC TERT1: 29.4;HHSteC: 55.2;HSkMC: 63.6;TIME: 24.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (6.36e-5)" "prognostic unfavourable (4.06e-4)" "prognostic unfavourable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 38.7 29.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.0 55.2 0.6 1.3 63.6 0.0 0.7 0.7 10.3 0.1 0.1 9.9 0.1 0.0 4.8 0.6 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.3 0.0 1.6 0.0 0.2 0.3 24.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Group enriched" "Detected in some" 8 "RT4: 29.8;SK-BR-3: 10.2;T-47d: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favourable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favourable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 29.8 0.1 0.1 0.0 10.2 0.0 31.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: " "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavourable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 0.6 5.0 1.2 5.3 3.8 1.7 3.4 3.9 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731456 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.4;intestine: 37.9;kidney: 35.4;liver: 40.7" "Cell line enhanced" "Detected in many" "Hep G2: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "neutrophil: 51.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 51.4" HPA060687 Supported "HPA060687: " "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favourable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" 2.8 4.9 2.4 17.0 7.6 1.6 1.8 2.5 4.7 3.0 7.5 2.7 1.5 28.4 2.5 4.0 4.9 2.7 7.9 4.9 4.6 2.6 35.4 40.7 11.7 8.1 3.8 2.5 2.0 1.9 3.2 5.3 2.3 4.1 1.9 3.4 2.9 6.6 0.6 1.4 3.1 37.9 1.9 6.0 6.4 2.0 2.0 2.2 5.4 2.2 3.8 4.5 4.3 1.7 1.7 4.0 51.4 6.6 1.2 3.2 1.6 2.5 2.0 2.7 4.7 1.7 6.4 1.1 6.2 22.1 4.6 5.2 3.3 2.4 7.4 1.0 2.4 0.1 5.0 2.0 6.1 4.7 5.6 4.3 4.2 26.8 10.6 8.0 9.4 3.9 3.1 14.5 13.8 3.6 2.3 10.5 1.2 3.7 6.2 8.6 4.5 2.4 8.6 4.2 7.6 3.4 8.7 2.9 3.6 5.5 5.6 12.3 6.4 5.8 1.4 3.3 1.4 0.1 2.8 5.5 5.9 7.2 5.8 5.3 3.3 1.3 6.6 2.2 0.5 2.0 0.4 0.8 0.9 0.6 4.0 1.7 0.5 0.6 51.4 1.2 2.4 1.2 3.2 1.6 2.4 7.6 2.5 4.7 4.6 2.6 3.8 2.5 4.1 2.2 GK2 "GKP2, GKTA" ENSG00000196475 "Glycerol kinase 2" Q14410 4 79406352-79408293 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "testis: 61.0" "Cell line enriched" "Detected in single" 52 "SCLC-21H: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 2.0" HPA060687 Uncertain "HPA060687: " "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GK3P "GKP3, GKTB" ENSG00000229894 "Glycerol kinase 3 pseudogene" Q14409 4 165277812-165279679 "Enzymes, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.0" "Cell line enhanced" "Detected in single" "TIME: 1.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 2.9" HPA060687 Uncertain "HPA060687: " "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "unprognostic (2.11e-2)" "unprognostic (3.94e-1)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (6.19e-2)" "unprognostic (6.99e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (4.56e-1)" "unprognostic (3.34e-4)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.2 1.0 0.0 0.1 0.0 0.1 0.0 0.4 0.8 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.1 0.0 GK5 MGC40579 ENSG00000175066 "Glycerol kinase 5 (putative)" Q6ZS86 3 142157527-142225607 "Enzymes, Predicted intracellular proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042606, HPA057998" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA042606: AB_10795509, HPA057998: " "unprognostic (7.79e-2)" "unprognostic (5.15e-2)" "unprognostic (2.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (3.60e-2)" "unprognostic (9.89e-3)" "unprognostic (3.13e-1)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (7.76e-2)" "unprognostic (2.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-3)" "unprognostic (4.49e-2)" "unprognostic (1.32e-1)" "unprognostic (5.59e-3)" 6.1 12.2 5.6 5.7 7.2 10.8 10.9 9.0 9.4 11.5 10.9 8.4 11.5 14.4 10.9 14.8 7.9 7.2 8.3 5.4 5.5 4.1 5.7 3.1 6.2 3.5 9.3 6.0 11.5 4.8 5.4 20.3 3.7 12.6 13.5 11.8 6.7 14.8 14.7 5.0 8.8 14.0 9.4 11.6 3.5 8.1 6.2 5.3 4.6 7.4 4.2 6.1 8.5 6.7 1.3 1.1 3.6 5.3 3.8 3.8 0.5 10.9 2.7 4.0 2.7 8.3 15.8 6.9 3.6 2.5 4.0 2.5 4.2 6.1 7.9 3.3 3.5 4.7 4.5 3.5 5.3 2.8 4.4 5.1 6.6 3.1 4.5 5.8 6.9 6.5 3.1 2.6 3.5 2.3 4.5 4.8 7.3 7.0 5.1 4.9 2.6 3.2 4.9 4.2 2.9 4.2 6.9 3.9 2.9 10.1 10.7 3.2 14.9 3.9 2.5 3.2 2.7 7.0 4.0 5.1 4.8 8.1 5.8 3.7 5.4 3.6 1.1 0.7 3.8 0.9 1.9 0.5 1.3 1.4 0.8 1.3 1.0 1.7 3.2 3.8 5.3 1.1 0.6 0.5 5.6 7.2 9.0 9.4 5.5 4.1 9.3 6.0 12.6 5.3 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 91.2;liver: 115.1" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 2.9" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 0.7" "HPA040251, HPA044094" Enhanced "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favourable (1.31e-6)" "unprognostic (2.69e-1)" 11.1 0.0 0.1 0.1 0.1 0.0 1.8 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 4.5 0.1 0.0 0.1 0.2 0.1 0.0 91.2 115.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.3 1.1 0.7 2.9 0.7 0.2 0.8 0.0 1.5 0.6 1.0 3.2 3.2 2.1 2.1 0.8 0.9 1.5 0.8 0.4 2.0 2.4 1.3 1.4 1.5 2.3 2.4 1.9 0.1 0.7 3.1 0.6 3.3 2.4 1.8 1.8 2.4 7.5 2.6 2.6 2.9 0.9 1.3 3.7 1.2 2.0 3.5 2.9 1.0 1.3 2.2 0.5 6.7 1.6 0.8 2.5 1.7 1.3 1.4 2.3 1.5 1.6 1.8 1.9 2.1 1.2 1.5 2.2 1.1 0.6 4.5 2.0 1.0 0.7 0.3 0.4 0.3 0.4 0.1 0.4 0.8 0.2 1.1 0.5 0.5 2.9 0.2 0.3 0.7 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 113.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.9;Daudi: 9.6;RPTEC TERT1: 3.2;U-2197: 2.5" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA039501: " "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favourable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favourable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.1 27.7 113.8 0.1 0.0 0.2 0.0 0.2 0.2 0.9 0.1 0.0 0.5 2.1 0.0 0.5 1.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.1 1.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.4 1.3 0.0 0.5 0.2 1.1 0.8 3.9 0.0 9.6 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.4 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.4 3.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.1 2.5 1.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.1 GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 11.2;cervix, uterine: 18.8;lymphoid tissue: 9.9;salivary gland: 25.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.8;BJ hTERT+ SV40 Large T+ RasG12V: 4.1;HAP1: 6.5;SK-BR-3: 15.5;U-2197: 7.5" "Cancer enhanced" "Detected in many" "breast cancer: 16.7;endometrial cancer: 15.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Not detected" "Not detected" "HPA060292, HPA065454" Uncertain Approved Mitochondria Mitochondria "HPA060292: , HPA065454: " "unprognostic (1.02e-2)" "unprognostic (3.79e-3)" "unprognostic (8.11e-4)" "prognostic favourable (9.05e-7)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "unprognostic (2.66e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-1)" "unprognostic (9.18e-3)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (7.42e-5)" "unprognostic (7.79e-3)" "unprognostic (8.28e-2)" "unprognostic (9.11e-3)" "unprognostic (2.31e-2)" 0.4 0.0 0.4 0.1 0.2 0.0 11.2 0.1 0.3 18.8 0.1 0.1 0.1 0.1 1.2 0.1 0.8 0.1 6.6 0.2 0.3 0.4 0.1 0.1 0.6 0.2 0.6 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.0 0.1 25.8 0.1 0.1 1.2 0.1 0.1 1.5 1.1 0.1 0.1 0.1 0.1 0.1 4.4 9.9 0.1 0.3 0.4 0.1 2.1 0.4 0.2 0.2 0.9 0.0 0.0 0.5 0.0 0.9 3.0 0.0 1.9 5.8 2.5 4.1 0.0 0.0 0.2 0.0 1.6 0.5 6.5 0.0 2.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.3 0.6 0.0 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.2 15.5 0.0 0.0 0.0 0.0 2.1 0.1 7.5 2.2 0.0 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.1 2.1 0.2 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.3 0.3 0.4 0.6 0.1 0.1 0.1 GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52293476 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 108.4" "Cell line enhanced" "Detected in many" "CACO-2: 18.9;Hep G2: 25.1" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favourable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" 6.4 4.9 1.9 8.4 5.0 5.2 4.8 2.7 6.2 2.3 7.9 7.1 4.2 23.8 4.3 4.8 2.8 2.5 7.2 2.7 1.9 2.2 10.7 108.4 3.1 6.5 2.5 4.9 2.3 3.6 1.9 2.5 3.1 3.9 2.8 3.5 4.7 3.2 3.0 7.0 1.9 17.8 1.9 1.8 5.5 6.0 2.7 1.8 3.3 3.1 2.4 5.9 2.7 2.2 8.3 9.1 10.9 9.5 5.7 11.8 6.3 2.2 5.5 3.0 1.1 16.0 2.2 1.8 2.5 2.6 4.7 3.5 18.9 1.9 5.9 1.5 2.2 1.5 1.7 6.2 0.9 1.6 1.9 8.3 6.7 25.1 1.5 2.7 5.0 2.1 3.1 6.9 2.7 9.0 2.2 4.3 3.6 1.7 4.6 2.2 1.6 4.6 1.5 2.7 8.9 4.8 3.1 2.2 2.2 2.4 1.3 2.5 3.1 1.3 3.8 3.7 4.4 2.4 4.8 4.5 3.1 3.8 2.5 4.5 2.8 3.0 9.5 10.9 11.8 5.1 6.1 8.3 9.0 10.3 9.1 5.7 6.8 10.1 7.8 5.7 6.1 5.6 11.7 6.3 1.9 5.0 2.7 6.2 1.9 2.2 2.5 4.9 3.9 1.8 GMPPB KIAA1851 ENSG00000173540 "GDP-mannose pyrophosphorylase B" Q9Y5P6 3 49716844-49723951 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014657 Uncertain Supported Nucleoplasm 10000 Nucleoplasm "HPA014657: AB_1849852" "unprognostic (3.48e-2)" "unprognostic (9.84e-2)" "unprognostic (2.77e-2)" "prognostic favourable (6.19e-6)" "unprognostic (1.01e-2)" "unprognostic (5.11e-3)" "unprognostic (1.54e-2)" "unprognostic (4.01e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-2)" "unprognostic (5.01e-3)" "unprognostic (5.73e-2)" "prognostic favourable (3.17e-4)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" 7.5 17.1 7.6 17.5 8.1 7.4 9.7 4.3 9.6 14.4 13.2 7.2 28.7 12.1 11.5 23.2 15.3 12.6 13.3 10.9 5.2 4.7 13.1 41.3 12.9 15.9 8.3 6.8 10.1 32.0 8.9 23.0 15.3 6.9 16.6 11.3 7.9 50.8 37.2 7.2 8.2 12.2 7.9 4.3 16.8 18.1 6.9 5.8 16.5 16.8 8.6 17.5 8.8 9.3 13.4 34.5 10.1 11.1 5.5 11.2 8.1 17.6 17.2 12.5 7.6 10.0 7.6 12.9 20.4 12.1 20.7 19.7 11.2 13.1 10.3 9.1 12.7 10.2 10.4 22.0 7.0 9.3 8.6 7.4 19.1 13.2 23.1 11.2 11.9 5.3 9.5 29.3 23.4 18.7 5.5 17.1 11.9 13.3 15.1 5.7 6.9 20.8 5.3 6.4 17.7 11.5 16.6 8.3 8.8 9.3 22.7 6.7 12.9 7.3 12.9 14.9 14.5 20.2 21.8 19.7 5.3 7.3 15.8 7.9 17.1 10.1 8.6 3.7 10.8 11.0 11.0 13.4 9.5 11.2 8.2 10.3 7.3 8.8 2.2 5.5 11.1 34.5 6.3 8.1 7.6 8.1 4.3 9.6 5.2 4.7 8.3 6.8 6.9 5.8 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 55.0;salivary gland: 45.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favourable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 7.7 6.7 6.0 6.5 8.3 8.3 16.6 11.1 12.1 7.9 20.7 7.0 4.6 2.9 8.0 3.9 7.6 6.7 5.2 7.6 7.8 6.8 6.8 55.0 5.5 6.0 6.0 7.8 9.8 8.4 4.1 7.0 20.2 10.2 10.1 30.1 4.8 45.3 5.0 10.5 3.7 7.2 11.7 10.9 4.5 4.9 3.4 5.3 3.2 4.6 4.2 7.9 8.6 7.9 3.9 2.2 1.2 2.7 2.4 4.2 1.8 4.4 19.9 8.9 7.6 10.1 10.1 12.9 6.2 7.9 8.6 11.1 4.8 14.2 5.8 6.6 10.3 1.7 6.7 2.0 9.6 10.9 0.6 5.0 11.7 6.6 6.9 0.1 14.3 6.6 2.0 14.3 13.5 3.6 6.3 12.1 8.3 0.7 8.1 2.6 5.1 11.2 6.7 7.5 1.6 47.6 8.2 7.6 6.9 6.6 2.3 5.7 2.1 5.1 5.2 5.7 5.9 6.8 5.4 5.3 11.3 3.2 7.8 4.3 8.1 0.7 1.7 0.9 2.7 2.2 1.8 2.4 3.4 2.9 1.4 3.9 4.0 4.2 1.2 2.4 2.7 2.2 1.5 1.8 6.0 8.3 11.1 12.1 7.8 6.8 6.0 7.8 10.2 5.3 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960758-42963880 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 83.9;pancreas: 100.1" "Cell line enhanced" "Detected in many" "Hep G2: 10.3;SCLC-21H: 12.2;T-47d: 7.8" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 17.7" "Low region specificity" "Detected in all" HPA027501 Enhanced Approved Cytosol 150000 Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favourable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.3 0.1 0.2 0.2 0.2 0.7 1.8 0.5 0.5 0.3 0.5 0.2 1.3 0.0 0.2 0.9 0.3 0.1 0.2 1.3 0.2 0.2 0.3 83.9 1.3 0.1 0.1 0.2 0.4 100.1 0.0 2.5 0.1 0.4 5.2 0.0 0.9 8.2 0.9 0.6 0.1 0.2 0.4 0.1 0.3 6.5 0.6 0.1 0.2 0.9 0.3 0.4 0.2 0.1 0.7 3.2 2.0 0.9 0.0 1.2 0.3 0.5 0.4 1.8 5.0 0.6 0.2 0.3 0.4 2.0 0.8 1.2 0.1 0.1 1.6 0.2 0.4 0.5 0.3 0.3 0.2 2.0 1.6 1.3 1.0 10.3 0.0 1.1 2.4 0.4 0.0 0.4 0.2 0.0 1.4 1.9 0.3 2.2 2.0 3.7 0.2 0.5 1.7 1.6 1.0 0.8 0.2 12.2 1.7 0.1 1.7 0.6 7.8 3.5 0.4 0.9 0.9 0.5 1.0 1.3 1.1 1.4 0.2 2.0 1.0 0.0 0.8 0.1 0.2 0.9 0.1 0.7 0.3 0.3 0.9 0.1 0.6 1.2 2.0 0.0 0.1 3.2 0.3 0.3 0.2 0.2 0.5 0.5 0.2 0.2 0.1 0.2 0.4 0.1 GNPAT "DAP-AT, DAPAT, DHAPAT" ENSG00000116906 "Glyceronephosphate O-acyltransferase" O15228 1 231241207-231277973 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cataract, Disease mutation, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (8.87e-2)" "unprognostic (3.28e-2)" "unprognostic (3.36e-2)" "unprognostic (2.56e-2)" "unprognostic (5.25e-3)" "unprognostic (1.91e-1)" "unprognostic (5.07e-2)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "prognostic unfavourable (8.29e-6)" "unprognostic (5.69e-2)" "unprognostic (1.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.68e-1)" 14.7 20.1 18.3 17.9 17.0 9.6 34.6 18.9 17.8 12.6 18.6 14.7 16.6 18.9 13.9 16.0 14.5 18.4 13.5 39.3 16.9 13.9 16.7 19.5 20.3 24.4 17.1 15.0 15.3 26.7 14.3 15.0 12.3 16.5 15.3 16.3 10.8 20.6 18.0 61.1 14.9 19.1 24.7 17.7 13.5 18.0 26.5 15.0 16.2 13.6 20.2 15.9 14.4 13.6 23.7 23.8 23.4 30.3 16.4 23.9 18.5 15.2 17.0 24.2 18.3 20.0 29.6 16.3 12.9 14.7 13.7 15.9 21.7 19.1 22.0 16.3 19.3 16.5 16.0 17.5 20.3 24.8 14.7 15.8 16.7 31.3 20.3 26.9 12.6 20.5 21.5 14.2 16.0 32.1 23.1 21.1 28.4 5.0 23.9 15.6 38.7 19.6 26.4 32.4 25.7 17.1 11.4 16.1 23.0 21.7 12.2 18.8 21.3 42.8 16.7 14.0 13.1 20.1 32.0 27.4 34.8 25.3 20.2 22.7 25.8 17.7 24.1 23.4 16.5 24.0 19.0 23.2 21.6 21.6 23.8 23.7 19.1 17.4 9.5 16.4 30.3 11.3 23.9 18.5 18.3 17.0 18.9 17.8 16.9 13.9 17.1 15.0 16.5 15.0 GNPNAT1 "FLJ10607, Gpnat1" ENSG00000100522 "Glucosamine-phosphate N-acetyltransferase 1" Q96EK6 14 52775194-52791668 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044647 Approved 17000 "HPA044647: AB_10795986" "unprognostic (4.55e-3)" "unprognostic (1.19e-2)" "unprognostic (4.47e-3)" "unprognostic (5.18e-3)" "unprognostic (4.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (3.19e-3)" "unprognostic (1.03e-1)" "unprognostic (6.81e-2)" "prognostic unfavourable (8.52e-5)" "unprognostic (5.82e-2)" "unprognostic (3.22e-3)" "unprognostic (2.16e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (4.05e-2)" 13.4 6.9 6.4 6.7 6.6 2.1 10.6 9.2 9.2 10.0 11.2 4.6 6.8 9.3 8.1 6.4 8.4 6.3 9.3 6.3 5.8 6.3 11.5 47.3 6.4 8.6 5.4 5.2 9.3 28.4 6.9 12.4 6.5 7.1 10.1 14.0 4.1 22.2 4.7 9.4 4.8 8.5 8.2 6.3 7.3 12.0 12.5 4.2 3.6 5.4 6.0 7.1 7.3 7.2 6.1 5.1 6.6 5.7 7.7 8.4 4.2 34.1 13.7 10.8 12.3 11.8 26.7 17.9 22.3 14.4 19.5 20.2 15.5 20.3 19.5 12.5 22.0 13.9 20.8 22.4 33.8 11.1 11.1 13.0 13.1 19.2 17.0 14.4 7.1 11.1 19.2 33.0 35.3 21.8 12.6 4.8 24.9 29.7 17.3 7.5 11.4 24.1 12.0 5.0 11.7 18.4 18.3 11.2 15.4 18.5 25.0 15.9 28.6 5.0 24.2 19.8 20.8 35.0 17.2 5.0 9.6 8.6 9.3 9.5 11.5 6.6 2.2 0.1 7.1 2.7 8.4 6.1 7.3 6.2 5.1 5.4 8.4 6.8 0.7 7.7 5.7 3.2 8.4 4.2 6.4 6.6 9.2 9.2 5.8 6.3 5.4 5.2 7.1 4.2 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase alpha and beta subunits" Q3T906 12 101745497-101830938 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease mutation, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" 47000 "Golgi apparatus" "HPA014558: , HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favourable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 15.2 6.5 21.9 11.9 23.0 15.2 12.2 13.9 25.6 14.0 21.3 10.3 5.9 10.3 9.0 6.5 11.7 7.1 11.0 15.9 17.9 13.7 11.0 7.3 19.6 20.3 14.4 13.0 6.6 11.4 29.9 9.0 10.8 10.9 15.6 22.5 11.3 37.6 10.2 10.8 18.1 14.5 11.7 13.1 15.4 15.2 7.4 10.8 24.5 10.5 8.6 12.6 14.7 14.8 3.9 5.8 5.9 3.4 14.2 16.4 2.7 8.3 8.1 3.0 5.1 25.6 12.2 9.4 11.9 24.6 11.8 15.5 6.2 5.9 17.5 8.6 16.3 10.9 14.0 15.3 18.5 8.2 7.3 7.5 7.5 8.8 4.8 6.8 15.2 9.4 8.5 11.2 6.6 20.7 11.6 5.2 11.0 12.7 20.4 9.6 10.4 5.9 4.8 15.5 23.5 19.0 21.7 6.6 5.4 19.8 14.1 28.0 14.5 4.5 20.3 11.2 6.1 9.3 6.6 14.3 14.6 10.0 12.7 10.1 6.9 5.9 3.1 3.4 16.4 2.9 5.4 2.4 3.6 8.9 5.8 3.9 4.6 7.1 1.2 14.2 3.4 5.8 2.6 2.7 21.9 23.0 13.9 25.6 17.9 13.7 14.4 13.0 10.9 10.8 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 116.9;liver: 82.9;skeletal muscle: 102.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol 130000000 Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favourable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favourable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 3.3 14.0 15.7 3.6 32.1 2.0 5.9 22.9 56.4 13.5 12.0 9.7 5.9 14.7 3.4 7.0 10.3 4.6 12.2 116.9 19.4 19.0 34.6 82.9 3.5 3.4 17.8 16.4 3.8 8.2 15.9 4.9 3.7 49.9 5.9 14.7 9.0 12.4 7.2 102.1 4.5 12.7 5.4 7.7 3.6 10.1 9.3 4.7 3.3 11.7 31.3 7.1 4.9 4.0 10.6 21.4 3.9 16.8 11.4 15.6 8.8 16.9 9.4 11.1 28.0 8.6 7.4 31.4 13.9 25.6 24.3 26.5 21.3 13.8 16.6 4.8 11.7 21.3 25.3 18.3 26.8 5.7 10.8 6.3 12.1 27.7 45.6 18.0 10.8 11.6 19.8 20.6 55.9 11.7 16.2 26.0 15.5 15.3 9.6 13.5 7.1 13.1 10.5 10.6 17.3 42.4 9.3 4.8 7.1 10.5 14.9 51.9 28.5 6.2 5.4 6.2 13.8 6.7 15.9 18.6 21.9 16.9 16.3 9.4 8.2 2.4 5.3 3.9 12.4 14.7 11.4 10.6 13.5 12.9 12.9 10.2 10.2 14.5 0.5 11.4 16.8 21.4 15.6 8.8 15.7 32.1 22.9 56.4 19.4 19.0 17.8 16.4 49.9 4.7 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734357 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 167.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018139 Enhanced "Intracellular and membrane" 7000000 "HPA018139: AB_1849903" "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavourable (1.61e-4)" "prognostic favourable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favourable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 6.1 21.0 12.7 8.0 19.1 5.5 10.7 19.4 35.7 10.6 15.9 16.0 33.3 10.6 10.4 19.5 17.7 13.5 8.9 78.1 15.8 16.7 24.6 85.5 7.1 11.1 16.2 17.8 8.7 8.8 27.0 13.0 7.3 27.7 17.2 18.8 23.4 13.0 20.5 167.8 10.4 9.4 13.5 12.3 8.0 13.6 10.8 9.9 10.7 12.3 53.9 15.0 15.5 11.2 14.3 17.6 3.5 9.9 14.5 24.5 14.3 27.1 36.9 19.5 23.6 14.1 12.8 25.5 20.9 22.3 41.2 22.6 31.9 24.6 60.8 24.9 23.1 40.2 41.6 40.6 52.6 16.7 38.2 16.4 20.1 35.6 17.9 26.2 15.1 12.3 23.1 25.9 22.7 41.3 32.8 6.3 20.9 24.3 32.6 25.4 26.4 71.7 35.8 29.7 58.3 38.9 40.0 31.1 22.6 40.0 43.1 15.0 21.8 8.6 16.6 15.0 27.5 11.7 26.5 14.6 13.5 49.8 16.1 26.3 15.1 2.3 9.9 3.5 15.2 8.6 23.5 14.3 18.0 18.4 17.6 10.6 16.7 15.3 0.9 14.5 8.5 15.5 24.5 14.3 12.7 19.1 19.4 35.7 15.8 16.7 16.2 17.8 27.7 9.9 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149864-112215377 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 107.3;liver: 56.6" "Cell line enhanced" "Detected in all" "ASC diff: 75.2;Hep G2: 20.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria Mitochondria "HPA046339: , HPA060090: " "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favourable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 107.3 17.2 11.4 2.6 12.1 1.8 30.8 6.6 11.0 2.0 3.2 6.5 5.1 2.2 4.1 32.1 2.4 1.9 3.0 5.8 12.2 2.9 2.4 56.6 2.2 2.3 7.2 7.3 3.5 2.8 3.2 2.3 1.8 5.6 2.3 2.6 12.0 6.8 2.9 3.6 1.8 3.3 3.4 3.8 1.7 2.4 2.8 7.2 2.8 6.1 2.4 2.3 3.2 1.6 3.2 2.0 0.5 1.2 1.1 3.4 1.0 2.7 2.1 2.8 3.7 75.2 2.7 3.7 2.6 3.0 1.9 1.5 4.9 1.6 1.9 1.4 1.8 3.5 4.5 2.2 3.6 1.4 2.4 1.8 2.3 20.2 2.3 3.1 1.0 13.1 3.8 3.4 7.0 1.6 2.3 1.7 2.2 1.5 2.6 2.4 2.3 2.9 2.7 7.4 1.4 1.2 1.9 1.2 3.6 3.6 1.7 4.1 1.8 1.1 1.2 2.2 1.3 2.7 4.2 1.8 2.0 4.1 2.6 2.7 1.6 0.0 1.0 0.5 2.5 1.2 3.2 1.9 1.9 1.9 1.2 3.2 2.0 3.4 0.0 1.1 1.0 2.0 1.9 1.0 11.4 12.1 6.6 11.0 12.2 2.9 7.2 7.3 5.6 7.2 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 7.3;BJ hTERT+ SV40 Large T+: 18.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.7;HBF TERT88: 4.1;U-2 OS: 10.3" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" HPA036841 Uncertain Approved Mitochondria Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 4.3 1.1 1.5 1.9 3.1 1.5 3.6 0.2 1.6 0.8 1.0 0.0 1.1 5.1 0.9 1.0 2.2 3.9 1.1 0.7 0.5 0.5 1.3 3.2 1.2 0.9 1.1 0.0 0.2 2.0 0.6 1.5 1.8 4.9 1.4 0.5 1.3 2.4 2.3 4.4 3.0 7.3 1.2 2.6 2.6 0.8 4.3 1.1 0.5 2.5 0.2 3.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.3 0.0 18.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.4 0.0 2.6 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 2.6 1.9 2.8 4.3 1.3 2.0 1.1 4.1 0.8 3.0 0.0 0.2 2.5 0.0 1.3 1.5 GPAT3 "AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324" ENSG00000138678 "Glycerol-3-phosphate acyltransferase 3" Q53EU6 4 83535914-83605875 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.2;kidney: 43.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 54.5;HMC-1: 20.0;U-87 MG: 23.8;WM-115: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 42.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA029414, CAB033749" Approved Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB033749: AB_2224941, HPA029414: AB_10601562" "unprognostic (9.51e-2)" "unprognostic (1.43e-2)" "unprognostic (5.67e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-3)" "unprognostic (2.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (2.92e-1)" "prognostic favourable (2.71e-9)" "unprognostic (3.74e-1)" "unprognostic (3.45e-2)" "unprognostic (2.53e-3)" "prognostic unfavourable (8.21e-4)" 7.9 0.7 0.7 5.2 1.4 5.2 17.5 4.2 2.9 3.7 18.0 1.2 1.3 20.2 3.0 2.1 5.1 2.1 6.0 24.8 1.2 2.2 43.7 9.0 3.2 4.5 1.9 0.8 12.9 1.7 11.8 5.8 1.2 9.5 2.6 5.7 1.3 3.6 1.9 35.9 1.9 47.2 3.7 3.0 4.3 7.4 4.6 1.4 0.9 26.6 14.6 3.4 4.5 7.2 0.0 23.2 42.0 9.7 0.5 1.8 2.9 10.4 10.3 0.0 0.1 0.5 1.3 0.2 0.8 1.5 0.2 0.2 0.7 54.5 0.0 1.1 2.0 2.3 4.9 0.9 0.1 0.7 2.3 0.0 3.2 10.0 1.4 2.9 20.0 0.7 0.0 0.4 1.2 5.1 8.3 8.2 0.2 1.0 0.7 0.7 0.2 4.4 0.1 2.3 3.9 10.3 0.7 0.2 0.0 2.0 2.1 5.7 0.4 0.5 0.2 2.5 4.4 2.4 9.8 0.4 0.7 0.0 23.8 5.9 18.2 42.0 9.7 1.0 0.2 7.7 1.8 0.0 1.0 0.6 23.2 0.0 0.7 0.3 26.4 0.5 6.1 0.1 0.6 2.9 0.7 1.4 4.2 2.9 1.2 2.2 1.9 0.8 9.5 1.4 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavourable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavourable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favourable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favourable (5.65e-4)" 15.7 27.4 14.4 17.8 17.2 16.6 28.1 43.8 21.9 16.9 14.0 23.1 22.7 13.0 22.8 12.0 13.1 14.6 15.8 14.1 14.0 13.1 20.8 26.7 18.7 13.8 18.5 13.6 16.6 17.3 35.7 22.3 23.3 20.5 15.1 15.1 21.0 20.8 15.5 42.1 14.5 14.6 23.0 18.0 17.5 17.8 15.5 16.6 15.2 14.5 12.4 19.4 16.6 14.9 9.1 18.9 10.8 15.0 4.9 12.1 11.1 14.6 16.3 19.5 15.2 21.4 26.0 17.2 31.9 27.5 24.2 25.3 10.9 29.5 20.4 22.4 26.3 8.5 22.8 14.4 31.4 21.8 12.5 23.8 18.1 10.0 12.5 2.5 34.4 16.3 10.6 25.2 9.1 24.8 17.7 24.1 24.8 6.2 22.2 6.5 20.8 8.7 13.0 19.5 11.0 14.7 22.0 12.8 17.7 12.4 17.1 34.2 23.7 16.1 18.1 25.1 17.6 28.7 23.8 13.0 17.4 22.3 20.6 14.1 24.5 10.8 15.0 6.6 12.1 14.3 11.3 8.3 9.3 11.9 18.9 9.1 8.5 8.2 3.5 4.9 12.0 7.1 8.7 11.1 14.4 17.2 43.8 21.9 14.0 13.1 18.5 13.6 20.5 16.6 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Uncertain "Cytoplasmic bodies" "Cytoplasmic bodies" "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favourable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavourable (4.61e-5)" 13.0 12.4 26.1 10.9 31.1 5.2 17.1 40.9 31.2 11.0 18.2 9.3 15.6 11.1 12.3 20.8 8.6 7.5 8.2 11.9 26.4 22.9 34.5 49.0 14.1 7.3 18.3 11.5 7.2 22.9 17.4 24.5 5.8 13.9 11.1 13.2 7.4 10.8 21.3 23.4 10.7 10.8 11.6 16.4 5.6 13.5 7.8 16.2 3.1 12.2 10.0 6.8 7.4 15.1 3.1 3.0 0.5 2.5 2.3 6.2 1.5 22.3 4.4 7.8 8.6 9.3 7.9 5.0 6.4 3.1 6.5 6.6 1.3 10.1 0.0 1.1 3.1 7.9 7.8 12.4 8.6 6.8 8.5 6.6 6.3 13.6 4.8 3.7 9.9 6.7 7.3 1.8 7.2 7.6 4.5 8.5 3.6 11.9 6.6 14.0 3.3 10.2 0.0 15.1 6.5 10.5 4.4 13.9 5.4 4.3 19.0 7.0 10.2 6.4 2.8 6.6 14.6 6.4 6.5 11.3 4.8 0.1 5.2 0.5 6.3 0.0 1.3 0.5 3.9 2.5 6.2 2.4 4.9 2.9 1.9 3.1 3.5 3.3 0.0 2.3 1.9 3.0 5.3 1.5 26.1 31.1 40.9 27.0 26.4 22.9 18.3 11.5 13.9 16.2 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 56.8;skeletal muscle: 27.0" "Cell line enhanced" "Detected in many" "Hep G2: 4.7;Karpas-707: 5.6;U-266/70: 6.0" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.3;non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 6 "monocytes: 2.9" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced 15000000 "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favourable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favourable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 9.0 0.8 1.7 8.7 2.2 1.1 3.9 1.5 2.3 0.2 17.4 2.0 4.6 10.9 0.2 1.7 0.9 0.5 19.8 16.9 1.7 0.9 8.7 56.8 0.2 0.2 1.3 2.2 0.4 3.6 0.5 1.1 0.1 2.0 0.7 3.5 1.6 17.0 2.7 27.0 6.1 19.2 0.2 0.7 0.4 8.6 0.8 1.6 0.0 0.6 13.9 3.3 0.3 0.5 0.0 0.5 0.0 2.9 0.0 0.0 0.0 0.5 1.5 0.4 1.1 0.9 0.0 1.3 0.8 0.0 0.0 0.0 0.4 1.9 0.8 0.7 0.0 4.3 0.0 0.0 0.0 1.5 2.7 0.7 2.5 4.7 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.5 5.6 0.0 2.6 0.9 0.9 0.6 1.0 0.9 0.3 3.0 0.0 1.8 1.2 1.7 0.5 1.4 0.2 3.8 0.2 0.4 0.3 1.3 1.3 0.2 6.0 0.4 0.4 0.8 1.9 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.7 2.2 1.5 2.3 1.7 0.9 1.3 2.2 2.0 1.6 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884378-46931297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 103.0;skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Hep G2: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 4.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria Mitochondria "HPA051514: " "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favourable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 19.9 4.1 20.2 2.1 17.8 1.9 6.4 3.9 15.1 2.5 3.4 11.8 10.0 1.3 2.1 13.4 30.8 3.7 4.4 3.0 13.4 8.0 9.8 40.4 1.4 2.1 12.9 7.8 1.5 103.0 4.3 4.3 1.8 11.3 10.2 2.6 1.5 27.6 8.5 60.9 14.9 1.7 1.9 11.3 1.4 15.4 6.0 12.3 0.7 3.6 19.0 14.6 1.9 2.1 4.2 1.4 1.3 0.7 0.0 0.4 0.4 12.9 5.9 7.5 28.5 10.6 2.3 13.7 9.0 3.4 9.7 6.2 20.1 5.5 9.1 7.9 6.4 10.4 13.5 13.3 6.5 4.2 6.6 3.2 3.4 48.5 7.3 22.7 3.0 4.9 11.7 9.5 14.8 4.7 2.6 7.3 3.2 23.1 4.5 19.0 7.9 17.0 0.1 8.3 21.1 3.9 6.4 23.5 12.0 4.6 24.1 12.2 6.2 20.8 3.5 6.8 13.3 4.5 7.2 35.1 10.6 25.7 10.4 14.8 3.6 1.3 0.7 0.0 0.3 0.0 0.0 4.2 0.0 0.3 1.4 2.5 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 20.2 17.8 3.9 15.1 13.4 8.0 12.9 7.8 11.3 12.3 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667155-113737735 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 51.5" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266410-67286556 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.2" "Cell line enhanced" "Detected in all" "NB-4: 55.2;REH: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA048330" Approved Approved Vesicles Vesicles "CAB005021: AB_562360, CAB037248: AB_1078280, HPA048330: " "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 13.1 10.7 24.5 35.8 17.0 78.2 17.0 32.9 35.3 12.8 17.2 12.2 12.6 17.5 11.4 9.9 20.2 12.6 17.6 13.6 21.9 17.4 13.0 14.1 19.1 42.8 13.4 19.0 9.8 10.4 9.7 12.2 12.7 15.7 17.8 16.2 9.3 17.4 20.8 20.8 23.5 26.3 12.2 12.5 59.6 17.4 6.8 11.1 35.9 10.1 13.6 37.5 17.1 15.5 4.1 6.0 21.0 18.3 3.8 5.3 7.4 7.5 5.3 5.2 8.8 4.2 3.8 5.2 4.5 4.3 6.2 5.1 11.8 12.5 38.8 7.3 4.2 10.2 7.6 6.1 3.2 47.2 4.7 22.0 6.1 5.3 5.2 46.1 44.2 3.4 7.1 4.9 6.6 7.9 7.9 19.9 5.3 14.0 25.6 55.2 6.5 8.0 73.3 10.3 11.5 6.3 9.9 10.5 5.7 6.7 9.8 16.0 9.1 50.2 4.3 4.9 6.5 6.2 5.0 12.7 11.6 34.8 6.4 27.3 4.5 6.9 10.3 10.5 5.3 15.9 4.0 3.8 4.0 4.3 6.0 4.1 3.2 3.1 21.0 3.8 18.3 5.3 2.6 7.4 24.5 17.0 32.9 35.3 21.9 17.4 13.4 19.0 15.7 11.1 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564849-25729294 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.0" "Cell line enhanced" "Detected in many" "HDLM-2: 22.6;SH-SY5Y: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.8;eosinophil: 5.6;intermediate monocyte: 8.0;memory B-cell: 4.9;myeloid DC: 3.7;naive B-cell: 6.2;non-classical monocyte: 7.4;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favourable (1.29e-4)" 28.0 6.0 11.9 12.4 10.8 7.0 11.3 7.9 18.9 4.7 4.0 3.1 0.7 3.0 5.7 3.1 2.7 9.1 5.0 4.6 15.7 8.3 3.0 3.4 9.4 14.1 9.7 9.8 4.1 8.4 4.4 8.2 4.5 9.6 8.2 4.3 4.8 3.7 1.9 1.4 4.1 6.1 6.2 4.9 23.2 4.0 14.8 2.7 11.6 4.5 1.3 15.2 6.7 2.5 6.2 3.7 5.6 8.0 0.0 0.4 1.6 0.0 2.1 6.5 2.1 4.5 0.6 9.4 0.7 2.0 2.0 3.5 3.4 3.7 11.8 0.2 0.1 0.1 6.4 4.8 6.1 22.6 4.2 5.4 0.7 7.4 0.2 17.5 9.2 1.1 3.3 1.4 2.5 0.3 0.5 0.0 2.4 2.9 12.5 1.2 4.6 0.0 5.6 10.3 2.0 0.0 3.5 15.1 20.5 1.1 0.0 4.9 1.8 7.0 0.2 0.0 13.3 0.1 2.5 1.4 4.6 9.2 8.7 6.2 2.0 0.6 4.8 5.6 0.0 8.0 0.3 4.9 0.0 0.3 3.7 6.2 0.1 0.2 0.3 0.0 7.4 3.2 0.4 1.6 11.9 10.8 7.9 18.9 15.7 8.3 9.7 9.8 9.6 2.7 GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963608-3040747 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028737, HPA057023" Approved Supported Vesicles Vesicles "HPA028737: , HPA057023: " "unprognostic (1.86e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (3.65e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (3.90e-4)" "unprognostic (3.20e-1)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" 3.4 3.6 5.4 1.6 5.1 1.7 4.8 12.5 5.9 3.0 2.1 4.2 1.0 1.5 2.7 3.1 2.4 2.0 3.0 5.6 5.2 4.8 2.8 2.3 2.4 1.6 5.3 5.3 3.4 7.9 3.9 6.2 2.2 5.9 2.4 2.0 3.1 4.0 2.9 5.0 2.9 1.7 2.8 5.4 1.9 2.5 41.2 3.7 1.6 4.1 1.6 1.7 2.5 3.3 1.2 2.5 4.5 2.0 1.6 1.7 1.0 2.4 0.9 3.0 8.5 7.3 7.0 1.8 4.8 2.1 2.7 2.4 2.4 0.8 5.5 2.1 7.6 0.8 3.9 4.0 2.4 3.8 3.9 6.0 3.4 2.8 4.3 2.4 2.2 4.7 6.2 4.8 2.3 5.1 5.6 7.2 6.4 2.8 5.1 5.1 2.3 6.7 6.5 3.8 2.2 2.6 3.1 17.3 5.3 2.9 1.3 4.3 6.5 3.7 5.9 7.4 1.9 5.0 4.2 7.4 4.2 4.2 3.7 5.3 2.5 4.5 1.1 2.1 1.1 2.0 1.4 1.1 0.7 0.7 0.3 1.2 1.7 1.6 4.0 1.6 0.7 2.5 0.4 1.0 5.4 5.1 12.5 5.9 5.2 4.8 5.3 5.3 5.9 3.7 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207589-119459742 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 36.5;HUVEC TERT2: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: " "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 15.9 8.3 3.4 16.8 7.8 2.7 10.2 6.5 5.0 12.5 18.8 3.9 4.5 12.4 13.4 12.2 8.1 7.7 19.5 45.4 4.2 4.2 4.3 5.7 27.6 8.8 3.7 2.5 16.5 3.5 26.2 6.3 24.0 4.5 7.5 6.4 5.6 5.0 6.7 12.8 4.7 10.4 10.8 4.8 17.0 13.9 3.5 4.7 9.8 8.9 10.7 8.6 9.5 13.6 9.3 2.2 6.5 3.7 0.2 11.3 4.2 4.0 2.3 6.0 6.1 13.8 13.3 1.8 7.8 36.5 4.9 2.7 1.9 5.9 4.3 1.8 12.2 1.0 2.6 8.6 3.2 17.1 2.1 0.7 5.0 7.7 9.5 0.2 2.2 1.8 1.3 9.8 1.4 28.8 0.4 4.2 1.7 0.6 4.0 3.9 0.9 6.0 1.4 0.8 1.0 0.8 1.6 2.0 5.5 2.7 1.2 7.5 0.1 1.0 8.7 2.6 1.9 15.8 3.0 0.9 4.6 2.6 5.5 4.8 2.5 0.9 3.7 6.5 5.3 3.2 0.4 9.3 7.7 3.8 2.2 9.1 11.3 5.0 5.0 0.2 0.9 0.0 9.2 4.2 3.4 7.8 6.5 5.0 4.2 4.2 3.7 2.5 4.5 4.7 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015327, HPA018903" Approved Approved Mitochondria 7500 Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavourable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favourable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 6.8 5.5 7.8 26.8 7.3 68.1 10.2 7.7 10.9 5.9 9.2 6.6 5.0 10.9 8.0 6.0 11.0 6.6 9.3 6.2 8.0 7.3 5.7 6.6 11.1 37.6 7.1 10.7 6.1 12.1 3.5 5.6 4.9 6.7 8.1 5.5 5.0 10.8 5.2 7.4 7.7 14.5 7.8 5.4 34.3 9.1 10.5 5.1 32.3 5.3 6.4 26.5 11.4 6.5 9.2 5.7 32.1 22.6 17.4 11.7 9.1 12.1 13.2 4.8 21.1 1.4 2.4 20.7 8.9 4.7 11.3 11.2 30.8 10.4 14.4 13.7 4.7 8.9 7.5 20.4 4.4 39.6 23.4 12.8 10.8 10.4 7.8 17.2 16.3 3.8 5.1 11.2 6.6 6.3 13.3 52.2 3.4 34.7 17.7 18.0 8.3 14.6 17.0 7.8 20.8 3.3 9.9 11.2 15.2 7.4 13.1 17.2 10.3 19.0 8.0 9.1 13.8 9.7 22.3 15.1 18.2 11.7 6.2 28.2 8.9 4.5 9.5 32.1 11.7 16.5 8.4 9.2 9.8 10.7 5.5 9.2 10.4 9.0 23.2 17.4 22.6 5.7 11.7 9.1 7.8 7.3 7.7 10.9 8.0 7.3 7.1 10.7 6.7 5.1 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 2.4" "Cell line enhanced" "Detected in some" "BEWO: 4.0;HeLa: 1.4;U-937: 1.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.2 0.5 0.3 0.5 0.4 1.5 0.2 0.9 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.3 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.2 0.2 0.6 0.3 0.7 0.2 0.2 0.3 0.0 0.4 0.2 1.6 1.5 0.4 0.0 0.2 0.4 0.1 1.0 0.1 0.3 0.1 0.3 0.7 0.2 2.4 0.4 0.5 0.6 0.1 0.0 0.1 0.1 0.6 0.4 0.0 4.0 0.1 0.0 0.0 0.1 0.2 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.4 0.5 0.2 1.4 0.2 0.0 0.4 0.3 0.1 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.2 0.7 0.4 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.4 0.2 0.0 0.0 0.5 0.2 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.1 1.7 0.2 0.2 0.4 0.3 0.4 0.2 0.6 0.6 0.5 0.3 0.1 0.7 0.5 0.5 2.4 0.5 0.3 0.2 0.2 0.1 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42230186-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 15.3 19.8 31.0 16.8 38.0 14.4 12.0 31.4 62.2 15.9 16.8 24.3 11.4 28.6 16.9 18.0 17.3 16.7 11.8 21.3 31.3 23.6 17.5 13.1 14.2 15.0 21.8 26.3 20.0 19.3 16.1 14.2 14.7 31.7 15.8 16.1 15.5 18.1 20.3 41.0 25.1 27.0 18.5 18.0 14.5 14.7 19.1 17.7 16.6 15.8 11.9 15.8 15.8 15.5 1.6 2.2 4.0 1.9 1.7 2.0 1.0 23.6 42.0 24.1 22.3 14.4 12.9 10.2 16.7 15.9 22.1 20.0 15.7 15.1 17.1 17.2 13.1 10.9 19.8 19.4 15.5 13.8 31.8 17.8 13.5 15.5 19.0 20.2 21.8 12.6 20.6 18.1 20.7 20.0 29.9 25.6 18.9 28.7 26.2 17.9 17.8 17.4 23.9 14.0 13.2 20.4 24.8 28.1 28.4 22.9 30.0 15.2 17.3 26.8 17.7 22.8 17.1 13.2 29.5 26.2 30.0 13.4 26.5 20.4 25.0 2.5 1.5 1.6 2.0 1.9 1.4 1.2 1.2 1.3 1.4 1.6 0.7 1.5 4.0 1.7 1.1 2.2 1.0 1.0 31.0 38.0 31.4 62.2 31.3 23.6 21.8 26.3 31.7 17.7 GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821323-120094417 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016263, HPA028017" Approved Supported Nucleoplasm 81000 Nucleoplasm "CAB016263: AB_2279451, HPA028017: AB_10600708" "unprognostic (1.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "prognostic unfavourable (8.20e-5)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.05e-3)" "unprognostic (6.79e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" 17.6 17.6 17.4 13.8 21.3 25.0 13.7 32.7 28.3 15.8 16.0 15.6 7.1 15.5 14.5 12.6 20.3 12.4 14.4 20.8 17.1 22.4 15.7 21.7 17.1 17.5 17.0 22.6 14.0 14.9 25.0 19.2 24.1 18.1 13.9 17.9 14.9 18.5 11.7 23.9 21.6 18.2 17.1 13.4 26.3 13.3 30.8 14.4 46.5 17.4 8.4 14.1 14.2 15.7 1.7 2.0 10.6 3.1 1.4 3.0 1.0 28.3 13.7 23.0 13.3 15.3 15.6 22.3 16.0 30.8 15.4 14.1 14.8 11.6 11.5 9.8 22.8 19.4 10.8 31.1 23.9 7.8 3.0 16.8 10.3 11.0 17.5 17.2 22.5 15.7 20.9 16.4 33.5 16.9 7.1 22.4 20.1 15.3 18.3 4.8 12.5 14.2 7.3 19.6 11.1 11.2 20.3 17.3 10.7 18.8 13.7 18.5 17.0 11.6 21.6 22.1 24.9 6.9 9.5 14.9 13.7 22.2 13.7 11.5 17.6 4.3 2.9 7.5 2.4 2.6 2.1 1.1 2.0 3.0 2.0 1.7 2.0 1.5 10.6 1.4 3.1 1.6 1.3 1.0 17.4 21.3 32.7 28.3 17.1 22.4 17.0 22.6 18.1 14.4 GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791664-52803910 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 119.4;intestine: 202.4;kidney: 79.7;liver: 214.4;testis: 78.2" "Cell line enriched" "Detected in some" 13 "Hep G2: 87.7" "Group enriched" "Detected in many" 6 "liver cancer: 555.4;renal cancer: 135.0" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favourable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" 0.6 119.4 0.6 0.7 4.2 0.0 0.6 0.6 0.7 0.8 64.3 4.3 0.6 59.9 0.6 1.2 0.7 6.9 16.4 0.6 0.6 0.0 79.7 214.4 7.1 0.6 0.6 0.6 8.5 16.9 0.0 0.7 0.9 0.7 1.8 0.2 1.0 2.6 0.8 0.6 0.1 202.4 0.6 0.6 0.6 10.7 78.2 0.6 0.7 0.6 2.1 4.4 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 87.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 4.2 0.6 0.7 0.6 0.0 0.6 0.6 0.7 0.6 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750089-52763569 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 63.4;liver: 192.2;pancreas: 54.1" "Group enriched" "Detected in some" 20 "CACO-2: 20.3;Hep G2: 15.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.2 1.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 6.4 0.2 0.2 13.4 0.2 0.3 0.2 0.0 9.9 0.2 0.2 0.0 63.4 192.2 5.3 0.2 0.2 0.2 0.3 54.1 0.0 0.2 0.3 0.2 0.7 0.0 0.2 0.3 0.2 0.2 0.0 27.6 0.2 0.2 0.2 1.5 14.1 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 20.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 15.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909685 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 36.5;fallopian tube: 32.4;placenta: 51.9" "Cell line enhanced" "Detected in some" "BEWO: 2.5;BJ hTERT+: 1.1;CACO-2: 1.5;HAP1: 2.8;HEK 293: 1.5;SK-BR-3: 2.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "pons and medulla: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.2 36.5 0.2 0.2 0.6 0.0 0.7 0.3 0.2 0.9 0.2 1.0 0.2 0.0 0.3 6.6 0.2 32.4 0.2 0.2 0.2 0.2 0.2 0.2 1.3 0.2 0.2 0.2 3.8 0.2 1.1 0.2 51.9 2.1 0.2 0.0 0.5 0.6 0.2 0.2 12.5 0.2 0.2 0.2 0.2 1.0 6.4 0.3 0.2 0.2 0.9 0.2 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.2 0.2 0.2 0.2 0.2 2.1 0.3 GSTA4 ENSG00000170899 "Glutathione S-transferase alpha 4" O15217 6 52977948-52995378 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 105.4" "Cell line enhanced" "Detected in many" "AF22: 32.2;ASC TERT1: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "non-classical monocyte: 17.4" "Lineage enriched" "Detected in many" 6 "monocytes: 17.4" "Low region specificity" "Detected in all" HPA048934 Approved "HPA048934: " "unprognostic (5.13e-3)" "unprognostic (2.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.38e-1)" "unprognostic (5.24e-2)" "unprognostic (3.63e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-2)" "unprognostic (5.05e-3)" "unprognostic (9.26e-2)" "unprognostic (3.31e-3)" "unprognostic (2.29e-2)" "unprognostic (1.34e-2)" "unprognostic (2.21e-1)" "unprognostic (4.07e-3)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 6.3 105.4 15.0 3.4 27.0 0.8 12.2 23.8 29.6 11.2 6.7 13.2 4.3 7.2 12.2 21.0 18.6 8.8 7.8 6.7 16.7 17.8 10.7 11.3 15.1 2.8 11.7 19.2 18.4 10.2 29.1 27.3 16.2 21.6 14.0 8.5 15.5 13.9 10.1 10.6 45.2 6.6 8.9 11.3 5.1 12.1 12.7 6.8 0.9 8.5 18.4 9.4 5.9 13.6 2.8 1.9 0.0 17.4 3.1 3.1 0.9 0.4 3.4 32.2 26.3 18.5 31.9 2.9 4.8 11.1 3.1 5.2 4.9 0.1 0.3 3.2 8.6 1.4 22.7 4.4 3.9 0.8 10.3 1.1 2.8 17.2 13.6 0.0 0.7 27.1 6.6 4.1 3.3 18.9 4.0 5.1 10.3 0.0 0.4 0.1 12.1 5.9 0.8 13.5 5.7 11.0 0.5 14.3 20.8 0.1 3.3 8.2 0.8 1.0 9.9 3.4 7.9 3.3 3.6 7.0 0.8 0.1 5.1 0.6 3.6 0.0 0.0 0.0 3.1 1.0 2.0 0.9 0.8 1.5 0.8 2.8 0.6 0.9 0.0 3.1 17.4 1.9 0.9 0.9 15.0 27.0 23.8 29.6 16.7 17.8 11.7 19.2 21.6 6.8 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52846095 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes 1300000 Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favourable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favourable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 38.0 45.3 14.0 45.3 19.9 29.0 43.0 5.6 19.6 30.4 69.0 19.9 35.7 58.0 24.8 39.8 37.8 27.4 55.2 56.4 15.0 13.1 67.6 97.1 35.4 52.2 24.3 16.3 22.7 39.9 46.2 20.7 41.5 23.9 28.0 43.5 34.4 72.9 35.8 38.9 30.0 91.0 22.2 17.5 58.5 34.8 18.9 20.8 27.1 48.0 56.6 50.3 29.4 26.6 32.8 57.1 35.7 75.4 22.3 99.0 95.2 27.1 19.6 2.7 24.4 43.3 62.2 13.0 16.1 27.6 14.4 28.8 11.8 69.8 15.5 23.0 23.2 41.2 10.7 25.2 12.6 29.8 11.6 12.6 14.7 18.5 29.8 15.2 20.6 56.1 31.0 16.6 11.8 38.2 17.6 18.9 38.5 20.9 15.5 27.6 6.5 29.7 13.4 0.4 30.6 49.9 15.0 11.3 15.4 29.5 48.1 24.4 23.1 21.3 22.5 7.8 7.3 20.5 13.6 32.4 15.2 3.5 28.3 61.3 16.1 35.7 67.9 25.8 41.1 74.8 39.6 32.8 76.4 52.4 57.1 21.9 39.5 38.1 21.2 22.3 75.4 23.9 99.0 95.2 14.0 19.9 5.6 19.6 15.0 13.1 24.3 16.3 23.9 20.8 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 163.2;seminal vesicle: 101.4" "Cell line enhanced" "Detected in some" "HEL: 26.6;HeLa: 31.8;HHSteC: 25.4;hTEC/SVTERT24-B: 23.0;HUVEC TERT2: 19.5;MOLT-4: 34.3" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved Cytosol Cytosol "CAB022669: , CAB047357: , HPA048652: , HPA055972: , HPA055973: " "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 14.5 25.4 15.2 6.9 15.6 2.9 8.2 5.6 19.2 22.0 7.8 16.9 0.0 7.7 9.8 20.2 22.5 13.8 8.2 6.4 14.4 6.8 14.1 163.2 7.7 1.0 7.8 32.1 29.0 18.2 41.4 5.3 2.9 8.2 38.1 6.6 25.7 11.8 101.4 25.1 18.8 17.7 18.2 6.8 21.7 7.5 15.1 11.2 10.9 7.6 1.6 14.5 30.8 19.5 14.6 34.9 14.1 18.9 13.3 17.3 10.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 2.2 8.2 0.0 12.7 0.4 0.0 0.1 0.2 0.0 0.1 26.6 31.8 0.5 25.4 0.0 0.2 0.0 0.0 23.0 0.1 19.5 0.0 17.8 0.7 0.0 34.3 0.2 17.1 0.0 0.1 0.1 3.3 2.8 0.0 1.6 0.2 0.0 0.1 0.1 0.3 14.0 0.0 11.4 0.6 0.2 0.0 14.3 18.8 1.1 9.8 0.3 0.6 0.7 12.2 14.1 14.8 18.9 15.7 14.6 15.8 13.7 34.9 14.6 16.5 15.6 1.0 13.3 7.4 19.2 17.3 10.0 15.2 15.6 5.6 19.2 14.4 6.8 7.8 32.1 8.2 11.2 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 41.0;HSkMC: 40.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" 930000 Cytosol "Cytokinetic bridge" "CAB040547: , HPA055972: , HPA055973: " "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favourable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 23.8 27.3 30.7 14.7 48.3 5.7 31.7 13.7 25.0 36.4 20.9 19.9 54.3 14.5 24.0 37.1 15.4 31.4 15.7 35.2 32.5 21.7 15.9 6.0 11.1 7.5 17.0 21.1 90.1 17.8 20.4 40.2 5.8 22.4 30.7 10.7 36.0 26.6 87.5 88.5 39.2 13.6 22.0 24.9 10.7 16.4 9.2 28.9 6.7 20.4 25.6 8.7 20.2 31.0 5.2 16.5 16.0 3.5 8.9 20.9 5.8 0.0 1.2 12.9 13.1 15.4 41.0 2.4 8.1 14.3 7.5 9.6 2.3 0.0 0.2 8.7 20.3 0.0 1.0 0.0 9.8 0.4 0.2 4.6 0.1 3.0 10.4 0.4 8.6 40.5 0.3 11.2 0.0 5.3 1.3 0.2 16.3 0.1 6.3 8.0 2.3 10.9 7.8 0.0 0.0 2.3 0.2 2.8 6.4 0.0 0.3 4.2 13.1 2.3 0.1 8.4 0.4 12.0 0.6 4.0 5.9 0.4 12.6 0.1 0.1 1.0 2.2 16.0 1.9 3.5 1.8 5.2 5.3 2.0 12.7 3.7 20.9 8.9 1.3 8.9 2.1 16.5 4.5 5.8 30.7 48.3 13.7 25.0 32.5 21.7 17.0 21.1 22.4 28.9 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 115.3;testis: 96.0" "Cell line enhanced" "Detected in many" "SK-BR-3: 44.8;T-47d: 94.8;WM-115: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 11.1" "Group enriched" "Detected in many" 7 "granulocytes: 4.1;T-cells: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Supported Cytosol 560000 Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: " "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavourable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 7.5 11.3 21.4 2.9 27.8 0.9 23.1 8.5 18.4 15.4 11.7 9.9 51.0 12.6 9.0 67.2 11.1 8.8 12.3 27.6 14.0 14.4 54.0 5.3 5.2 2.4 9.6 22.0 32.3 26.5 7.3 9.4 5.8 30.7 13.6 5.6 13.4 4.5 115.3 15.5 15.0 7.5 15.9 13.3 3.3 14.2 96.0 6.4 0.1 15.8 15.6 3.3 17.4 12.0 0.6 0.8 4.1 0.3 1.0 11.1 1.4 0.0 1.3 9.7 0.0 13.2 8.1 1.6 10.5 1.8 11.5 11.2 4.2 0.3 0.0 6.1 5.3 0.5 1.9 4.3 16.0 0.0 2.9 9.8 31.8 6.3 14.1 0.0 22.8 8.1 5.3 17.3 0.0 14.2 0.8 0.1 5.1 5.7 2.6 0.2 1.0 18.2 0.0 6.2 0.4 3.2 22.5 17.1 9.2 21.9 44.8 2.0 94.8 14.3 11.1 0.1 4.2 11.8 6.9 1.5 2.4 0.0 0.1 0.0 36.8 0.8 0.3 4.1 4.2 0.1 1.2 0.6 5.3 3.1 0.1 0.6 11.1 5.5 2.0 1.0 0.2 0.8 2.3 1.4 21.4 27.8 8.5 18.4 14.0 14.4 9.6 22.0 30.7 6.4 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656081-109674836 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 85.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "eosinophil: 69.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.8" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" 660000 Cytosol "Cytokinetic bridge" "HPA048652: , HPA055972: , HPA055973: " "prognostic favourable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 12.5 17.6 14.0 12.3 20.2 3.6 10.9 12.9 24.7 12.6 33.2 18.0 9.4 85.3 12.1 15.3 15.9 11.0 14.5 14.7 13.7 12.3 27.2 22.0 7.4 10.1 14.8 16.9 31.4 12.2 23.1 9.9 5.1 15.8 14.7 23.2 20.5 15.4 26.3 47.4 10.6 77.2 19.0 16.1 16.2 14.7 11.8 14.0 4.0 14.9 14.5 12.8 22.2 14.2 3.6 7.8 69.8 3.0 2.5 3.1 2.3 5.3 2.4 4.3 32.5 9.7 15.0 5.5 1.7 14.0 4.1 5.4 17.1 0.6 5.0 6.7 7.7 5.5 11.1 5.8 2.6 7.4 0.0 10.8 10.0 15.3 15.8 3.7 13.2 9.4 5.8 5.2 0.0 3.3 5.0 7.5 2.8 4.9 3.1 16.4 3.3 12.9 6.6 2.4 7.3 16.0 3.8 3.0 7.2 0.0 28.1 21.7 7.6 8.0 1.4 4.7 18.7 5.2 2.5 11.2 19.6 0.4 15.5 5.5 13.3 2.0 2.9 69.8 2.7 3.0 1.6 3.6 2.0 3.1 7.8 2.8 2.0 2.3 0.4 2.5 0.7 2.7 2.8 2.3 14.0 20.2 12.9 24.7 13.7 12.3 14.8 16.9 15.8 14.0 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109712255-109775428 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "breast: 237.6;ovary: 66.1" "Group enriched" "Detected in some" 7 "fHDF/TERT166: 17.6;HHSteC: 7.6;HSkMC: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 5.7;T-cells: 1.9" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Cytosol "Cytokinetic bridge" "HPA048652: , HPA055972: , HPA055973: " "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 5.8 3.5 25.7 2.6 23.4 1.6 237.6 15.8 24.6 27.2 4.2 14.0 4.7 2.1 14.0 12.0 4.8 19.8 9.0 4.8 24.9 6.2 2.9 2.1 5.7 2.6 4.9 17.9 66.1 2.7 1.6 2.7 1.6 8.9 12.8 4.0 23.0 3.9 11.9 2.4 3.7 3.5 9.8 11.0 3.5 3.9 5.1 11.9 0.0 2.6 2.1 3.2 10.5 16.1 0.0 5.7 0.6 0.2 0.7 1.9 0.9 0.0 0.0 0.0 0.0 1.5 1.5 0.2 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.1 1.3 0.0 0.2 0.2 0.0 0.7 0.0 5.7 1.9 0.9 25.7 23.4 15.8 24.6 24.9 6.2 4.9 17.9 8.9 11.9 GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 137.3" "Cell line enhanced" "Detected in many" "SK-MEL-30: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced Approved Nucleoplasm,Cytosol 200000000 Cytosol Nucleoplasm "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favourable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavourable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" 29.6 31.9 19.9 21.8 24.4 35.8 20.0 15.0 24.3 17.8 29.7 16.8 17.8 36.3 16.5 21.4 22.6 15.2 24.7 67.9 19.7 21.5 32.7 137.3 32.0 35.7 23.2 23.1 19.7 21.2 18.6 23.2 26.3 17.0 18.2 20.8 18.0 25.3 21.2 42.7 13.3 41.0 21.4 18.9 26.8 19.8 7.0 14.2 30.8 32.9 24.0 16.8 28.0 18.8 18.7 55.4 85.5 68.3 21.8 25.5 68.0 31.0 21.3 16.5 28.2 23.2 44.3 7.2 40.6 72.1 26.9 29.4 26.7 33.2 27.7 17.6 26.9 17.9 10.8 36.0 28.4 13.8 25.9 20.4 15.2 58.3 41.5 26.1 34.3 33.6 15.4 39.1 47.3 51.5 41.9 17.3 56.4 16.9 20.3 36.8 15.2 14.9 14.9 10.8 11.7 40.0 20.0 8.2 10.3 13.1 9.4 121.1 10.3 21.1 47.5 32.0 16.8 49.7 36.1 0.3 0.4 0.2 59.9 45.5 12.6 85.5 68.3 19.2 18.3 57.2 22.0 18.7 22.6 23.4 55.4 15.0 19.7 19.8 19.5 21.8 43.9 25.7 25.5 68.0 19.9 24.4 15.0 24.3 19.7 21.5 23.2 23.1 17.0 14.2 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304945 "Enzymes, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 24.8;hTCEpi: 21.6;hTERT-HME1: 23.4;MCF7: 14.1;T-47d: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048141 Approved "HPA048141: " "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favourable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.9 3.8 7.5 2.2 15.7 2.1 13.1 2.1 9.8 6.7 6.8 6.9 15.5 6.2 4.3 16.7 11.0 10.6 6.7 1.0 4.6 4.8 10.6 3.3 3.7 0.6 3.5 7.6 7.1 37.3 18.1 24.0 1.3 3.2 10.6 8.8 9.4 13.2 18.0 1.8 12.3 6.0 2.8 3.2 1.0 9.8 30.3 5.4 1.7 10.7 9.6 4.5 5.9 6.7 1.3 1.0 5.1 0.7 2.9 3.7 0.8 9.5 0.8 0.2 0.4 0.3 0.9 1.1 4.5 8.3 2.3 2.4 0.2 24.8 1.3 4.3 0.5 13.1 0.3 5.6 0.7 0.5 1.7 0.2 2.1 1.4 2.2 0.3 0.3 1.8 21.6 0.1 23.4 0.4 0.7 2.0 0.6 14.1 0.1 0.2 0.9 0.8 0.3 0.3 0.3 6.0 7.1 0.4 0.5 3.2 2.4 1.3 18.4 0.1 1.2 0.7 3.8 0.4 0.2 1.7 3.4 0.2 0.7 0.4 0.2 0.5 0.5 2.4 1.3 0.7 1.3 1.0 1.9 0.8 0.2 1.3 2.1 1.3 5.1 2.9 0.3 1.0 3.7 0.8 7.5 15.7 2.1 9.8 4.6 4.8 3.5 7.6 3.2 5.4 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583595-67586656 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 298.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol 120000000 "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 24.2 25.3 20.2 23.8 21.7 46.2 39.5 15.5 19.8 51.8 51.9 23.5 125.4 35.2 43.5 41.9 181.6 60.8 51.1 45.3 18.3 23.5 44.2 5.9 61.0 39.4 25.5 19.9 33.4 60.7 44.1 33.8 57.9 46.0 37.0 17.9 59.9 50.2 110.8 33.7 58.5 34.0 30.1 22.8 25.1 48.5 15.4 15.4 29.8 91.6 131.5 75.6 40.8 79.5 25.3 191.4 12.4 168.2 70.1 40.7 167.2 68.1 93.0 45.3 70.5 35.1 39.6 41.9 29.8 40.0 45.6 35.5 170.8 71.7 0.1 68.4 47.1 99.7 122.4 131.2 12.9 47.5 44.5 3.3 67.7 0.0 52.1 22.4 39.9 49.1 298.4 36.3 35.1 68.3 73.9 19.0 35.6 0.2 51.3 62.5 86.7 39.9 47.9 7.6 0.2 72.5 0.2 15.4 44.0 41.8 13.6 135.0 0.2 37.7 36.8 21.0 53.4 44.0 21.6 11.8 73.8 25.0 23.9 37.1 43.6 2.3 168.2 12.4 40.7 125.7 15.0 25.3 18.4 33.3 191.4 24.3 15.3 27.3 7.0 70.1 79.4 76.2 18.3 167.2 20.2 21.7 15.5 19.8 18.3 23.5 25.5 19.9 46.0 15.4 GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B (gene/pseudogene)" P0CG30 22 23957414-23961186 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "breast: 83.4" "Cell line enhanced" "Detected in many" "AN3-CA: 22.4;HHSteC: 33.0;SK-MEL-30: 22.8;T-47d: 25.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA000750 Uncertain Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA000750: AB_1849804" "prognostic favourable (5.06e-4)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (4.51e-2)" "unprognostic (7.13e-2)" "unprognostic (8.41e-3)" "unprognostic (2.58e-1)" "unprognostic (7.99e-2)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (4.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-2)" "unprognostic (2.19e-3)" 1.6 11.7 2.7 0.7 1.9 0.0 83.4 0.0 4.2 2.6 1.5 0.1 1.7 2.9 2.6 1.4 1.1 2.4 1.7 2.9 1.3 6.1 2.0 0.1 2.5 3.1 3.2 0.9 3.6 0.8 6.1 0.2 1.2 2.5 1.3 11.4 0.7 2.7 1.4 0.9 2.6 0.5 2.5 0.1 0.7 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 6.4 0.3 0.0 22.4 0.4 0.5 0.9 3.1 1.8 4.6 4.8 9.6 0.0 0.0 5.1 7.8 9.4 0.0 9.9 2.1 0.0 0.8 0.3 12.6 1.5 33.0 0.0 3.6 13.6 1.6 13.1 2.7 3.6 0.0 0.0 2.7 0.1 0.0 0.0 0.1 4.7 0.0 16.7 0.0 10.1 0.0 0.4 9.4 3.1 0.0 22.8 25.2 0.3 12.2 3.8 2.5 0.5 2.4 0.0 0.0 0.0 2.4 0.0 9.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320884-77331597 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 90.4" "Cell line enhanced" "Detected in all" "MCF7: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol 62000 Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favourable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favourable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favourable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 4.6 12.9 5.6 5.9 6.8 2.8 8.5 2.1 9.0 5.0 8.1 10.8 7.5 8.1 4.1 9.5 9.0 5.5 8.0 5.5 5.4 5.0 8.9 90.4 4.4 10.7 6.9 6.9 2.8 7.1 9.3 5.1 11.0 5.8 8.0 8.0 9.5 22.5 4.7 14.8 7.4 7.2 3.8 7.9 5.0 5.9 18.2 5.2 8.6 8.3 14.3 8.9 4.9 4.5 8.2 15.3 7.2 16.0 3.4 5.6 5.0 6.4 12.4 9.8 6.9 6.2 8.6 16.6 4.1 4.1 7.6 10.8 4.2 16.4 14.4 5.8 4.8 8.3 6.7 7.8 7.3 7.6 6.6 7.0 4.7 8.8 9.8 2.6 5.8 8.1 8.5 4.4 7.5 6.5 5.8 13.3 5.1 60.2 4.0 5.5 2.9 9.9 6.9 10.3 11.2 11.6 8.0 10.8 9.8 9.0 18.0 12.7 29.4 3.8 4.4 5.9 20.2 6.7 3.0 10.0 10.7 12.7 15.5 3.9 7.5 6.6 11.1 7.2 1.9 16.0 1.9 6.4 3.4 2.8 15.3 8.2 2.9 2.4 1.1 3.4 13.5 10.4 5.6 5.0 5.6 6.8 2.1 9.0 5.4 5.0 6.9 6.9 5.8 5.2 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694955 "Enzymes, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA069369: " "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favourable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 6.9 8.5 12.3 6.6 11.6 7.8 11.6 23.8 13.9 10.8 8.0 7.0 5.6 5.3 10.2 9.3 11.4 9.5 7.4 7.8 8.7 8.1 8.7 7.4 8.9 10.9 9.4 11.6 15.0 8.4 16.6 10.1 9.7 8.9 8.9 7.7 7.6 11.3 8.4 11.6 14.5 6.6 8.6 5.6 6.3 8.1 16.9 6.4 11.6 13.3 5.3 9.3 8.8 7.9 2.3 2.1 1.5 1.5 2.1 3.1 0.9 8.3 12.0 15.3 13.0 7.6 8.9 11.0 8.1 10.7 11.5 8.5 14.6 6.3 13.1 5.5 10.5 19.5 23.3 13.2 12.8 7.9 9.6 11.0 17.3 6.2 7.4 16.2 7.0 6.9 10.1 11.7 15.4 9.8 17.9 6.7 8.3 13.7 9.9 7.6 19.3 11.7 9.8 18.5 11.5 8.5 7.1 21.2 14.4 14.5 14.8 9.0 20.6 6.7 10.2 19.1 10.7 8.7 12.1 2.8 6.3 14.6 8.1 10.3 11.7 0.1 1.5 1.2 2.5 1.3 2.0 2.3 2.2 3.1 1.2 2.2 2.3 2.4 1.5 2.1 1.2 2.1 2.0 0.9 12.3 11.6 23.8 13.9 8.7 8.1 9.4 11.6 8.9 6.4 GUK1 ENSG00000143774 "Guanylate kinase 1" Q16774 1 228139962-228148984 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028118, HPA048587" Approved Uncertain Nucleoplasm,Cytosol 240000 "Nucleoplasm, Cytosol" "HPA028118: AB_2756308, HPA048587: AB_2680453" "unprognostic (9.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.60e-3)" "unprognostic (7.91e-2)" "unprognostic (8.54e-3)" "unprognostic (1.24e-1)" "unprognostic (3.55e-3)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (7.32e-2)" "unprognostic (3.38e-2)" "unprognostic (5.28e-2)" "prognostic unfavourable (8.85e-5)" "unprognostic (2.91e-1)" "unprognostic (5.41e-1)" "unprognostic (2.39e-2)" "unprognostic (6.12e-2)" 44.6 38.2 106.4 32.5 76.0 76.7 43.0 25.2 74.4 31.5 33.3 30.1 27.3 41.5 26.3 34.1 77.0 28.0 42.5 61.6 93.1 43.9 31.9 43.5 34.6 39.0 60.0 52.9 24.7 62.2 12.8 26.0 29.2 40.1 25.5 12.1 37.4 66.5 29.4 35.8 59.6 42.1 34.8 49.6 36.1 44.3 22.2 34.9 27.5 31.6 29.3 24.1 45.9 44.5 43.9 97.7 110.1 62.9 55.8 83.7 84.5 57.4 20.3 8.9 27.7 27.0 32.6 45.0 38.3 19.7 22.4 17.6 11.6 40.0 21.7 45.5 25.0 38.2 7.7 42.1 2.4 33.0 59.7 12.9 50.1 25.2 49.2 14.5 22.7 45.2 25.6 15.6 12.6 30.2 34.7 34.6 18.3 48.0 65.7 31.5 28.1 88.0 25.2 16.9 57.5 21.0 27.1 29.6 53.1 24.7 42.3 49.6 31.2 31.5 52.6 40.9 27.0 59.8 63.0 32.0 34.6 23.9 51.5 23.8 41.2 55.5 57.1 110.1 77.3 59.8 75.2 43.9 64.8 83.7 48.9 36.6 48.7 61.1 74.9 55.8 62.9 97.7 64.6 84.5 106.4 76.0 25.2 74.4 93.1 43.9 60.0 52.9 40.1 34.9 GXYLT1 "FLJ43151, GLT8D3" ENSG00000151233 "Glucoside xylosyltransferase 1" Q4G148 12 42081845-42144879 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" 3000000 "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (1.22e-1)" "unprognostic (9.89e-2)" "unprognostic (5.22e-3)" "unprognostic (1.77e-2)" "unprognostic (4.42e-3)" "unprognostic (1.46e-2)" "unprognostic (1.64e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-2)" "unprognostic (8.16e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-2)" "prognostic favourable (3.91e-4)" 9.1 7.6 9.7 8.3 10.9 9.4 8.6 12.5 8.9 8.7 5.9 9.7 5.2 5.9 8.6 5.8 7.7 7.9 6.1 6.4 8.1 6.2 9.7 18.4 8.8 7.0 8.7 4.4 10.4 7.9 11.2 25.6 16.0 11.5 7.5 7.4 9.0 8.6 8.2 5.5 6.3 8.1 5.5 7.4 9.2 6.7 13.4 7.8 6.0 13.2 2.8 9.0 7.6 7.8 1.4 2.7 4.9 4.0 2.4 2.0 0.9 6.5 5.6 6.4 6.3 4.6 12.1 24.3 14.8 10.0 11.0 11.2 12.9 13.5 5.7 11.7 8.1 3.1 10.8 4.8 20.5 9.5 12.2 9.5 4.7 10.5 7.3 10.1 9.0 9.3 4.1 16.8 7.5 14.5 5.9 10.2 14.0 4.5 6.5 6.2 7.8 5.4 3.1 13.1 5.1 6.7 9.9 3.3 5.6 10.5 6.0 8.7 12.3 8.0 12.4 7.9 26.9 4.6 9.3 13.4 15.1 7.3 10.7 27.7 4.8 0.3 1.8 4.9 1.2 3.6 0.8 1.1 1.9 1.6 2.7 1.4 1.7 1.5 1.4 2.4 4.0 0.9 2.0 0.9 9.7 10.9 12.5 8.9 8.1 6.2 8.7 4.4 11.5 7.8 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888073-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.5;HSkMC: 12.9;MOLT-4: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: " "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavourable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavourable (2.42e-5)" 8.7 7.2 3.1 6.2 4.0 2.1 5.2 1.1 4.0 10.2 4.5 8.1 3.4 0.9 8.4 9.3 4.2 6.7 12.4 20.6 3.4 2.4 2.2 1.0 5.2 2.4 5.6 4.7 24.8 11.9 2.8 3.8 4.9 4.2 11.3 2.7 10.7 8.0 5.2 2.2 2.6 2.5 12.0 5.4 1.0 2.6 8.4 4.7 14.9 12.1 3.7 2.3 12.2 6.9 0.4 3.0 1.7 0.1 0.8 1.4 0.1 0.1 1.2 0.0 7.5 6.9 13.5 1.1 1.2 2.8 2.7 6.6 0.3 0.8 0.0 2.1 3.2 0.1 0.7 1.5 2.6 0.0 0.9 0.0 5.0 7.9 8.7 3.1 0.0 12.9 0.7 6.5 1.0 0.0 3.7 0.1 1.6 1.7 23.1 0.1 4.4 1.5 0.1 6.4 0.0 0.8 1.1 0.7 3.4 6.4 0.3 0.8 2.5 1.0 0.0 2.9 9.3 9.0 4.2 0.7 0.1 0.1 7.6 1.5 5.1 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.7 0.8 0.1 3.0 1.4 0.1 3.1 4.0 1.1 4.0 3.4 2.4 5.6 4.7 4.2 4.7 GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991341-149027668 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030497 Approved Supported Vesicles Vesicles "HPA030497: AB_10602326" "unprognostic (2.68e-2)" "unprognostic (6.31e-3)" "unprognostic (3.21e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (6.15e-5)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (7.75e-3)" "unprognostic (1.29e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" 10.8 7.9 7.0 8.5 8.5 55.7 10.0 9.2 7.5 10.6 31.0 6.0 11.9 4.8 15.6 15.4 18.1 11.1 12.0 32.0 8.0 9.0 8.5 6.3 9.1 14.7 11.6 7.1 13.3 14.3 6.5 7.8 6.5 10.0 16.3 7.6 7.7 11.3 19.4 113.0 4.7 8.4 32.5 8.1 13.6 12.8 47.3 7.4 4.2 9.4 39.6 8.5 28.7 14.6 7.0 26.7 16.8 26.7 17.7 32.5 17.5 18.5 12.0 9.0 10.0 24.9 26.1 12.2 27.4 22.8 40.0 37.4 15.7 19.0 0.0 13.6 31.7 5.7 23.5 12.1 40.4 6.2 10.1 14.2 5.7 17.8 22.5 14.4 21.4 14.3 19.8 13.2 16.7 22.9 8.7 33.8 22.9 32.6 2.8 11.5 10.7 9.8 7.9 13.6 26.6 11.0 17.4 7.4 3.5 14.4 19.9 15.5 19.8 15.4 19.0 20.5 6.1 14.6 20.0 30.7 17.1 13.2 17.3 22.2 6.6 7.2 23.4 16.8 17.4 24.5 32.5 7.0 11.6 18.1 26.7 5.1 6.3 10.7 11.6 17.7 26.7 10.7 15.9 17.5 7.0 8.5 9.2 7.5 8.0 9.0 11.6 7.1 10.0 7.4 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828788-2882820 "Enzymes, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 76.7;brain: 21.2;breast: 30.4" "Cell line enhanced" "Detected in many" "AF22: 17.7;BEWO: 12.8;CACO-2: 13.1;Hep G2: 14.2;NTERA-2: 17.4;SK-MEL-30: 37.7" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: " "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favourable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 76.7 1.4 4.6 1.3 4.6 0.5 30.4 2.1 3.7 2.1 3.5 8.2 0.7 1.2 4.2 0.9 1.0 3.6 1.7 1.7 3.9 2.9 1.4 9.9 0.7 0.7 5.5 2.9 1.9 3.2 0.4 0.5 1.6 12.9 2.7 2.0 4.2 2.8 4.4 0.5 1.2 1.3 2.8 21.2 0.5 2.2 0.8 5.1 0.0 1.3 0.5 0.6 2.9 1.4 1.0 0.6 0.6 0.4 1.2 0.7 0.0 0.0 5.4 17.7 0.0 10.6 0.0 12.8 0.5 3.1 3.1 3.9 13.1 0.3 0.0 1.4 2.2 0.0 10.0 0.2 3.0 0.1 2.8 0.0 0.2 14.2 3.1 0.0 4.3 3.8 0.1 0.3 0.0 0.0 0.1 0.0 3.2 0.8 0.0 0.4 17.4 0.1 2.9 5.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 37.7 1.7 10.7 0.0 0.0 3.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.2 0.7 0.5 0.4 0.3 0.1 1.0 0.3 0.2 0.6 1.2 0.4 0.6 0.4 0.0 4.6 4.6 2.1 3.7 3.9 2.9 5.5 2.9 12.9 5.1 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968125-48993310 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol 10000 "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: " "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavourable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 9.7 7.3 5.1 6.1 6.5 16.0 10.6 11.3 6.2 5.3 7.3 6.2 5.8 6.1 6.2 6.9 11.5 5.9 6.1 37.3 6.8 4.0 7.2 4.3 5.0 6.3 5.3 5.5 6.8 4.4 6.4 5.1 5.0 5.9 8.7 6.1 12.4 7.2 7.6 106.1 8.1 6.1 6.8 6.0 5.8 7.3 2.2 5.5 6.4 5.2 42.6 9.0 7.9 6.9 6.7 15.9 8.2 10.5 12.8 10.9 7.3 28.3 11.3 8.4 11.5 19.6 7.7 16.7 19.7 13.9 20.8 24.4 11.0 9.3 11.8 12.0 19.2 20.3 14.0 25.0 18.2 7.3 20.3 9.8 14.5 9.7 11.0 10.7 7.3 19.0 12.0 13.4 11.4 17.4 6.8 15.9 26.0 10.8 13.2 9.3 4.5 13.1 11.2 14.7 11.6 20.6 30.4 5.2 7.3 17.5 22.9 4.6 12.1 11.1 13.4 25.6 9.9 11.5 21.3 13.2 13.6 5.8 26.1 9.4 5.7 8.2 10.5 7.5 8.8 6.3 10.9 6.7 7.6 8.2 15.9 5.5 6.3 5.6 4.4 12.8 8.5 8.6 10.1 7.3 5.1 6.5 11.3 6.2 6.8 4.0 5.3 5.5 5.9 5.5 GYS2 ENSG00000111713 "Glycogen synthase 2" P54840 12 21536189-21604847 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.1;HEL: 1.8" "Cancer enriched" "Detected in single" 29 "liver cancer: 12.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 8 "T-cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039482 Approved "HPA039482: AB_10795107" "unprognostic (7.22e-3)" "unprognostic (2.85e-2)" "unprognostic (8.88e-2)" "unprognostic (1.78e-2)" "unprognostic (5.68e-2)" "unprognostic (3.16e-1)" "prognostic favourable (7.62e-5)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.68e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.66e-4)" 8.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.1 75.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 2.4 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.6 1.8 0.2 0.0 0.3 0.5 0.4 0.5 0.2 0.0 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.3 0.2 0.0 0.5 0.2 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728093-104859919 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 41.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: " "unprognostic (6.32e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (1.12e-2)" "unprognostic (3.75e-2)" "unprognostic (3.75e-3)" "unprognostic (1.22e-3)" "unprognostic (4.63e-2)" "unprognostic (7.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (1.12e-2)" "unprognostic (2.06e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (1.75e-1)" 6.4 5.4 12.7 3.7 16.1 4.3 6.1 15.5 13.1 6.6 4.8 6.8 2.5 3.6 8.5 2.9 8.1 5.4 5.0 5.2 7.5 8.6 9.4 2.9 5.7 3.5 8.8 9.6 6.4 3.8 12.0 7.4 41.9 10.2 6.1 3.3 7.7 6.2 6.9 4.4 4.8 3.6 6.5 9.5 4.1 3.9 14.1 8.9 5.4 7.1 2.7 3.9 6.4 5.8 2.9 2.4 2.2 2.9 2.2 3.9 1.6 3.5 2.5 10.7 13.4 6.4 8.5 12.7 7.2 11.1 4.6 6.9 2.3 2.1 2.0 3.2 5.4 2.4 2.7 4.9 9.7 8.2 6.8 7.1 2.3 3.1 6.4 6.1 2.3 5.7 4.5 5.9 5.0 7.5 6.8 2.3 9.0 2.6 4.5 3.6 4.7 2.4 7.2 12.2 0.8 3.7 6.1 5.8 8.7 3.9 4.1 2.1 2.6 8.4 7.9 3.7 3.1 9.9 6.8 3.3 3.6 6.9 3.9 5.8 6.7 0.0 1.9 2.2 3.7 2.9 3.9 2.9 3.7 3.6 1.9 2.7 3.9 3.0 0.4 2.2 1.5 2.4 1.2 1.6 12.7 16.1 15.5 13.1 7.5 8.6 8.8 9.6 10.2 8.9 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290468 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 126.0;skeletal muscle: 155.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria 1100000 Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favourable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 23.3 45.5 24.8 11.0 24.7 9.9 16.6 16.6 17.4 13.8 21.4 31.1 19.3 43.6 17.1 16.2 20.6 13.9 12.6 126.0 18.0 20.0 45.8 62.4 12.8 16.1 34.8 18.3 16.2 23.7 19.9 13.1 12.6 27.8 15.8 22.8 19.9 27.2 15.9 155.6 13.2 35.0 20.3 29.5 15.3 19.5 15.8 23.8 10.6 22.4 44.9 14.5 18.5 12.8 20.2 45.2 21.5 49.1 23.8 26.8 33.9 22.7 18.0 12.6 22.5 77.7 43.0 12.7 19.2 29.4 19.8 19.4 21.5 22.2 11.4 13.5 31.4 18.0 20.9 27.1 24.3 25.7 18.2 26.2 10.7 42.0 33.3 21.1 20.1 41.6 44.8 20.5 33.5 36.6 21.9 18.5 41.2 16.7 11.8 40.8 8.7 19.6 13.1 41.6 21.7 40.7 32.4 6.0 20.7 32.9 37.5 50.4 23.2 37.8 25.3 18.7 19.5 17.5 13.8 13.9 20.9 20.1 21.5 33.8 18.5 21.0 49.1 18.9 14.2 43.4 18.1 20.2 19.3 17.6 45.2 14.8 18.0 16.3 21.5 23.8 33.2 15.3 26.8 33.9 24.8 24.7 16.6 17.4 18.0 20.0 34.8 18.3 27.8 23.8 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.7;lymphoid tissue: 13.7;ovary: 23.6" "Cell line enriched" "Detected in some" 4 "U-87 MG: 49.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "eosinophil: 5.9;neutrophil: 1.6" "Lineage enriched" "Detected in single" 15 "granulocytes: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA067602: " "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 23.7 0.5 0.6 13.7 1.3 2.8 1.0 1.5 1.9 0.6 1.2 0.4 1.1 0.1 0.8 2.5 1.3 5.8 5.5 5.9 1.4 2.0 0.3 0.6 4.5 0.3 0.6 0.3 23.6 2.2 0.0 0.3 0.3 0.6 0.4 0.5 1.0 0.3 1.2 2.1 2.7 4.0 3.6 0.9 0.7 0.7 0.9 0.3 0.3 0.3 0.8 0.3 1.8 0.3 0.1 0.1 5.9 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 11.7 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 49.8 0.0 0.1 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.6 1.3 1.5 1.7 1.4 2.0 0.6 0.3 0.6 0.3 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641390 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.8" "Group enriched" "Detected in some" 4 "HBF TERT88: 33.9;hTEC/SVTERT24-B: 32.6;LHCN-M2: 43.3;U-138 MG: 85.2;U-251 MG: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052060 Approved "Nuclear speckles" "Nuclear speckles" "HPA052060: " "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.8 0.9 1.6 9.1 2.4 0.0 5.5 0.8 1.7 4.0 8.5 2.0 0.0 2.6 1.5 2.5 4.8 3.9 7.7 8.3 1.7 1.7 1.2 2.7 6.5 4.5 1.8 0.6 1.2 1.8 0.3 0.7 2.1 5.7 4.3 5.6 2.7 1.9 0.1 2.7 3.8 9.5 3.7 4.2 0.3 2.3 3.2 2.6 0.4 1.7 5.5 2.1 5.7 1.4 0.0 0.2 0.7 0.2 0.3 0.1 0.0 0.0 0.5 0.0 0.0 1.0 2.5 0.0 4.8 3.6 6.3 11.0 0.0 0.0 0.0 0.0 4.3 0.8 0.0 0.0 33.9 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 6.7 0.0 32.6 3.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.7 0.0 5.6 0.0 0.0 0.4 0.0 0.1 2.0 0.0 1.1 0.0 0.0 0.0 85.2 0.3 7.9 25.2 0.0 0.0 0.0 1.8 0.0 1.7 0.5 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.7 0.3 0.2 0.2 0.1 0.0 1.6 2.4 0.8 1.7 1.7 1.7 1.8 0.6 5.7 2.6 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105564-69118719 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 22.6;urinary bladder: 22.9" "Cell line enhanced" "Detected in some" "HaCaT: 14.1;PC-3: 75.1;RT4: 29.7" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031554, CAB033850" Supported Approved Microtubules Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavourable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.4 0.2 0.4 0.4 1.0 0.3 5.5 1.1 1.3 3.3 3.7 0.4 0.4 1.9 0.8 1.1 22.6 0.7 3.5 2.4 0.6 0.6 1.2 0.7 18.0 0.4 0.4 0.4 0.9 2.2 0.1 1.0 3.3 1.1 3.5 2.3 0.6 7.6 2.1 0.6 5.7 2.1 1.4 0.4 0.4 9.0 2.0 0.4 0.5 4.0 11.7 11.1 22.9 13.6 1.5 1.2 2.2 1.4 0.4 2.0 1.1 0.9 4.7 0.2 0.2 0.1 0.1 1.8 0.3 0.1 0.2 0.1 1.0 2.4 0.2 0.5 0.1 14.1 0.7 8.4 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.3 0.3 0.8 0.1 0.0 0.1 0.0 0.5 0.3 0.1 4.2 75.1 0.5 0.0 0.0 7.7 29.7 5.3 0.2 0.5 0.0 0.0 0.2 0.2 0.1 0.2 0.2 8.2 0.4 0.3 0.2 0.0 0.3 0.0 0.1 0.8 1.4 2.2 1.4 0.7 1.3 0.7 1.1 0.5 1.2 1.5 2.0 0.7 0.5 0.4 1.1 1.0 1.5 1.1 0.4 1.0 1.1 1.3 0.6 0.6 0.4 0.4 1.1 0.4 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 7.5;lymphoid tissue: 26.7;testis: 26.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027422, HPA030698" Approved Supported Nucleoplasm Nucleoplasm "HPA027422: AB_10601812, HPA030698: " "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 1.2 0.3 0.3 11.8 0.6 7.5 1.8 0.5 0.3 0.5 1.5 0.2 0.0 2.2 0.3 0.4 2.8 0.6 1.3 0.6 0.2 0.2 0.8 0.4 2.6 5.8 0.4 0.0 0.4 0.5 0.0 0.3 1.3 0.2 0.7 1.5 0.2 1.0 0.0 1.2 0.9 3.6 0.4 1.2 4.9 1.7 26.7 0.3 26.7 0.7 1.7 7.3 0.8 1.0 2.8 1.5 2.1 0.6 0.0 1.2 0.4 7.5 8.2 7.6 8.6 0.5 1.0 6.4 6.9 5.3 13.7 13.5 6.4 3.1 18.5 4.0 3.8 12.3 13.7 6.7 13.1 0.1 11.5 9.2 6.7 3.8 0.3 5.3 9.5 0.6 0.5 10.3 6.4 6.2 8.1 16.3 6.9 3.9 10.7 3.1 6.7 5.7 11.1 9.6 5.0 2.0 5.3 3.1 4.5 6.1 4.2 2.4 4.2 5.0 3.2 6.1 7.0 6.8 12.1 3.1 3.5 9.0 3.6 7.7 7.3 0.4 0.6 2.1 0.2 0.5 0.2 0.7 0.8 0.0 1.1 2.8 1.2 0.2 0.2 0.0 0.0 1.5 0.1 0.4 0.3 0.6 0.5 0.3 0.2 0.2 0.4 0.0 0.2 0.3 HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983682 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" 24.3 23.7 14.3 20.8 21.4 30.9 25.7 18.4 16.7 17.6 18.2 14.0 17.7 11.8 20.7 15.6 21.3 17.7 14.8 26.2 16.7 13.0 27.5 22.1 18.8 26.9 21.2 12.9 21.8 23.0 22.3 32.2 21.1 21.4 20.8 19.3 13.1 25.5 15.6 53.9 18.6 15.8 22.9 20.5 22.5 20.2 15.9 21.5 35.4 26.1 31.8 27.8 22.1 16.9 21.0 16.0 29.9 32.1 25.9 28.1 19.2 34.0 16.3 28.8 26.3 15.3 15.9 20.3 35.6 23.8 39.3 41.1 37.7 23.6 38.2 23.1 21.5 27.1 31.1 29.1 60.8 21.5 30.9 33.7 26.9 34.0 7.5 42.5 21.2 9.5 16.9 51.8 17.4 24.8 34.8 25.1 44.6 23.8 33.3 38.9 23.9 17.1 26.7 36.3 25.9 23.4 34.4 18.4 15.1 29.8 16.7 30.2 23.2 43.2 12.5 35.4 27.3 29.7 35.8 11.0 25.4 45.0 23.8 30.5 30.5 23.8 21.1 29.9 20.8 24.5 25.8 21.0 22.1 21.3 16.0 18.4 22.2 24.2 24.0 25.9 32.1 8.2 28.1 19.2 14.3 21.4 18.4 16.7 16.7 13.0 21.2 12.9 21.4 21.5 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052188-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 107.1;lymphoid tissue: 72.6" "Group enriched" "Detected in some" 8 "THP-1: 22.6;U-937: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 50.8;eosinophil: 62.5;intermediate monocyte: 96.5;myeloid DC: 31.6;neutrophil: 73.0;non-classical monocyte: 107.1" "Group enriched" "Detected in many" 15 "dendritic cells: 31.6;granulocytes: 73.0;monocytes: 107.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005195, HPA063768" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB005195: AB_631619, HPA063768: " "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavourable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 12.3 5.8 5.9 40.8 13.1 20.8 4.0 1.8 5.3 3.0 5.8 6.1 0.9 5.9 2.5 5.7 3.1 5.9 6.5 8.8 6.0 3.7 4.0 7.9 20.9 50.3 11.2 1.2 3.4 2.8 0.7 2.9 8.8 8.0 3.8 5.9 3.1 4.1 1.9 3.1 2.8 7.8 10.2 9.1 72.6 3.7 2.6 8.2 5.8 3.3 1.2 16.4 9.4 3.5 4.7 31.6 73.0 107.1 1.1 0.1 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 22.6 0.0 0.0 0.1 0.0 0.0 0.6 0.1 3.3 0.0 64.8 0.0 0.5 50.8 62.5 0.1 96.5 0.1 4.7 0.1 0.1 31.6 3.7 0.1 0.0 73.0 1.1 107.1 2.8 0.1 40.2 5.9 13.1 1.8 5.3 6.0 3.7 11.2 1.2 8.0 8.2 HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100112-31207804 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA002929: AB_1850574, HPA054461: " "unprognostic (6.71e-2)" "unprognostic (4.86e-2)" "unprognostic (5.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (1.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.29e-2)" "unprognostic (3.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.51e-1)" "prognostic favourable (1.20e-6)" "unprognostic (6.53e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (9.91e-3)" 22.0 22.3 14.2 21.0 16.8 22.0 18.5 22.3 18.9 19.4 17.9 15.2 20.2 11.5 17.6 15.7 30.4 16.1 15.2 26.2 13.5 14.3 18.0 35.2 15.0 14.1 14.5 14.5 18.2 15.1 34.8 20.5 27.0 18.8 16.8 15.5 16.8 18.9 16.4 88.5 24.3 16.3 15.6 13.7 16.4 18.8 18.9 14.4 16.7 24.8 23.0 18.6 18.6 22.3 10.6 9.3 12.6 8.6 8.9 8.1 3.3 28.4 17.8 15.7 9.8 49.6 26.0 15.0 17.4 17.6 15.6 13.5 13.3 15.4 22.3 18.5 31.8 19.3 20.8 15.7 23.7 13.6 8.5 22.8 14.7 53.1 23.1 23.7 16.8 22.8 21.8 17.5 27.5 28.6 16.4 10.4 24.2 23.3 9.2 10.1 11.9 16.2 17.0 18.1 9.7 24.3 29.5 11.6 13.6 25.5 17.7 15.4 18.6 15.3 28.6 18.1 14.2 13.0 14.7 11.4 16.1 25.2 8.6 12.0 15.2 12.6 8.6 11.3 7.1 7.1 8.1 7.2 8.0 6.3 9.3 10.6 6.7 6.6 4.4 8.9 5.3 7.8 8.0 3.3 14.2 16.8 22.3 18.9 13.5 14.3 14.5 14.5 18.8 14.4 HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "NK-cell: 6.7" "Lineage enriched" "Detected in many" 7 "NK-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037767 Approved Approved Nucleoplasm Nucleoplasm "HPA037767: AB_10671378" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.26e-2)" "unprognostic (3.34e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-2)" "unprognostic (9.37e-4)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.54e-3)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.67e-5)" "unprognostic (6.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.84e-2)" 8.7 8.8 16.5 6.9 17.9 2.4 10.8 20.3 19.5 14.3 10.1 5.1 9.1 4.6 17.2 16.6 8.3 12.1 11.4 8.1 11.9 8.7 7.3 4.7 8.7 4.7 5.8 11.3 16.8 7.4 14.4 18.6 10.2 6.5 24.8 7.6 7.5 7.7 24.3 7.7 6.8 6.0 18.4 6.8 5.3 7.5 9.7 6.4 2.9 9.8 5.1 3.6 13.7 10.5 0.6 0.4 0.1 0.8 6.7 1.0 0.5 4.0 2.1 21.2 8.7 4.7 5.1 3.8 3.3 4.5 6.8 6.3 0.2 3.9 0.0 2.9 3.4 0.3 5.7 2.4 8.4 4.4 7.1 2.3 14.9 1.3 2.3 0.4 1.5 5.2 2.2 4.9 4.2 5.1 3.1 10.6 10.5 1.9 2.5 1.3 8.8 2.1 6.3 14.0 2.4 4.7 1.1 5.0 5.3 6.5 1.5 6.6 9.6 1.4 5.3 6.9 4.7 0.4 6.3 0.7 1.4 5.9 6.0 0.0 3.9 0.0 0.1 0.0 1.0 0.8 0.6 0.2 0.5 0.7 0.4 0.6 0.5 0.6 0.1 6.7 0.2 0.0 0.1 0.5 16.5 17.9 20.3 19.5 11.9 8.7 5.8 11.3 6.5 6.4 HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved 34000 "HPA027467: AB_10600710" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.14e-5)" "unprognostic (1.74e-2)" "unprognostic (2.92e-2)" "unprognostic (7.42e-2)" "unprognostic (2.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.35e-1)" "prognostic favourable (1.85e-6)" "unprognostic (3.19e-1)" 18.4 16.9 9.6 16.7 11.1 9.2 25.9 12.4 14.8 11.2 38.0 14.8 11.7 34.1 12.4 12.4 16.7 9.1 14.6 8.7 9.9 8.4 16.4 22.9 10.5 11.3 10.9 7.9 14.1 24.1 22.9 8.0 11.8 10.8 10.4 19.5 9.7 27.0 15.4 24.2 20.1 59.3 12.0 9.9 14.0 13.9 11.7 9.7 11.9 13.3 14.8 12.5 13.8 12.0 8.7 9.9 10.4 15.1 5.0 10.9 7.5 11.2 10.2 6.5 10.6 23.1 14.5 13.0 10.8 16.4 11.9 13.5 14.5 3.5 5.3 9.2 17.6 10.5 15.5 11.2 10.7 9.8 12.0 8.5 14.9 12.7 20.2 6.6 14.3 15.6 19.2 20.3 7.9 26.5 18.9 6.0 15.1 9.6 8.3 5.4 9.0 15.6 9.9 11.8 7.6 17.5 13.3 15.8 6.6 14.5 25.2 12.8 8.2 6.2 19.8 13.8 11.0 17.1 12.2 7.7 9.0 2.9 22.1 7.2 6.7 9.4 10.4 10.4 10.9 15.1 9.1 8.7 8.9 9.3 9.9 5.1 7.5 8.9 4.0 5.0 8.2 7.5 9.0 7.5 9.6 11.1 12.4 14.8 9.9 8.4 10.9 7.9 10.8 9.7 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112599-43566001 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;kidney: 15.4" "Cell line enhanced" "Detected in some" "A549: 5.5;U-266/70: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Approved Supported Cytosol Cytosol "HPA007203: , HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.7 0.5 10.3 0.8 12.1 1.4 0.8 13.6 24.0 0.6 0.8 1.1 0.0 0.4 0.8 1.7 2.6 0.5 4.0 0.4 3.9 4.1 15.4 0.6 0.6 1.3 3.8 15.5 1.0 0.4 1.7 0.4 0.6 10.2 3.2 0.5 0.6 1.0 0.8 1.8 2.1 0.6 0.7 1.4 0.6 1.0 3.7 1.6 0.0 1.5 0.0 0.8 1.2 0.6 2.4 1.6 7.0 1.7 1.6 0.7 0.1 0.1 5.5 0.6 0.8 0.0 0.0 0.0 1.6 2.8 0.1 0.6 0.0 0.0 0.2 3.0 2.7 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.4 0.2 0.2 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.3 0.9 0.5 0.0 0.0 0.0 0.1 0.2 0.7 0.5 0.1 0.0 0.4 0.0 0.0 0.8 1.1 1.3 0.4 15.6 0.5 0.0 3.5 0.4 0.0 6.4 1.7 1.1 0.7 1.0 0.5 1.0 0.7 0.3 0.2 2.4 0.6 0.7 7.0 1.6 0.9 1.6 0.2 0.1 10.3 12.1 13.6 24.0 3.9 4.1 3.8 15.5 10.2 1.6 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593692 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 26.6;HUVEC TERT2: 15.0;SCLC-21H: 17.4;TIME: 19.7;U-138 MG: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.7;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 9 "granulocytes: 7.7;monocytes: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034609 Enhanced "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 8.8 3.3 6.7 2.6 12.6 0.6 4.2 15.7 17.2 4.6 1.2 11.6 0.0 1.1 3.0 1.0 5.5 6.3 4.8 14.0 6.7 4.3 3.4 5.6 16.4 3.5 8.2 9.3 1.3 2.1 14.7 5.9 15.5 9.5 1.5 1.3 1.2 2.2 1.3 2.7 2.7 1.7 3.1 5.8 11.6 2.1 5.8 8.8 0.0 7.9 1.6 4.2 2.4 2.5 0.6 0.7 7.7 5.2 0.0 0.1 0.1 0.0 0.7 1.2 0.0 0.7 2.3 0.9 1.5 3.9 1.2 1.4 0.1 0.0 0.7 0.3 7.2 1.7 0.5 0.1 2.5 26.6 0.9 0.0 1.1 0.1 0.1 0.2 0.2 0.5 0.7 8.9 3.1 15.0 0.1 0.0 3.6 0.9 0.0 0.3 1.4 0.6 0.0 0.3 0.0 0.0 0.0 17.4 1.4 1.1 0.2 0.0 0.0 0.1 19.7 12.0 0.8 2.6 0.3 0.1 0.0 0.7 3.0 0.0 0.1 0.2 0.5 1.3 0.0 1.9 0.0 0.5 0.1 0.0 0.7 0.6 0.1 0.0 7.7 0.0 5.2 0.0 0.1 0.1 6.7 12.6 15.7 17.2 6.7 4.3 8.2 9.3 9.5 8.8 HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 28.8;testis: 45.2" "Cell line enhanced" "Detected in many" "MOLT-4: 23.9;NB-4: 26.7;THP-1: 20.0;U-937: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 16 "cerebellum: 18.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favourable (2.56e-4)" "prognostic favourable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" 3.5 2.2 6.7 5.1 10.2 7.7 5.5 3.6 11.6 6.1 4.4 4.2 1.4 3.4 2.8 3.4 1.9 1.8 4.5 3.1 9.5 10.1 1.8 1.4 4.9 9.8 8.2 5.6 3.8 1.5 0.6 3.9 3.8 10.7 2.7 6.6 1.3 2.4 2.6 2.0 2.6 5.2 2.5 6.9 8.0 3.2 45.2 2.5 10.3 1.7 1.2 7.3 5.5 1.6 5.4 10.6 18.2 12.0 22.9 28.8 15.9 5.9 3.0 0.2 0.0 0.2 0.2 0.0 1.4 0.5 3.5 0.5 8.9 9.4 0.0 3.3 2.7 0.0 0.0 0.0 2.2 1.9 0.0 15.1 11.5 0.0 3.1 8.9 13.5 2.9 0.1 0.7 0.0 0.7 0.0 6.8 0.1 15.1 23.9 26.7 8.8 1.3 10.4 0.0 0.5 0.0 6.5 14.9 0.0 12.8 3.6 0.0 0.0 20.0 0.1 0.0 11.8 6.4 0.0 4.1 5.2 0.0 0.0 35.2 0.1 16.0 8.8 18.2 28.8 10.1 26.0 5.4 14.2 26.0 10.6 2.9 11.8 21.7 8.6 22.9 12.0 8.5 13.1 15.9 6.7 10.2 3.6 11.6 9.5 10.1 8.2 5.6 10.7 2.5 HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833942 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain "HPA049749: " "unprognostic (9.72e-2)" "unprognostic (7.51e-2)" "unprognostic (3.43e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-1)" "prognostic favourable (4.87e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.89e-3)" "prognostic favourable (3.66e-4)" "unprognostic (1.24e-1)" "prognostic favourable (1.36e-6)" "unprognostic (2.87e-1)" "unprognostic (3.36e-2)" "unprognostic (9.04e-3)" "unprognostic (3.94e-1)" 14.4 11.7 20.3 12.9 23.5 28.9 15.5 30.4 29.7 17.4 15.3 14.7 13.8 7.0 15.8 8.9 10.3 10.7 12.1 17.6 19.4 14.3 11.9 11.4 14.9 15.2 12.8 23.7 23.8 11.5 44.8 20.1 12.7 19.1 11.4 11.8 11.0 11.4 14.0 31.7 14.6 13.9 15.7 11.7 17.4 13.5 13.5 15.8 16.6 17.2 11.3 15.3 12.9 11.6 9.8 7.0 17.6 5.7 2.8 6.6 1.4 7.4 9.8 10.9 3.8 19.4 12.5 3.6 5.9 7.6 6.2 7.1 6.0 3.0 11.1 5.5 11.0 8.1 17.6 5.0 8.4 8.5 6.0 24.1 13.9 4.3 3.2 17.8 14.5 8.9 4.9 8.6 8.5 12.8 24.2 5.0 5.3 12.1 6.2 3.5 5.4 5.0 6.8 12.1 6.5 2.5 18.4 9.8 4.9 10.4 7.1 6.2 3.5 7.1 14.2 8.0 7.4 6.8 7.7 5.5 9.4 7.8 4.5 13.3 2.7 17.6 3.7 7.4 5.0 3.3 3.8 5.3 5.5 4.4 3.2 9.8 5.6 5.6 12.9 2.8 5.7 7.0 6.6 1.4 20.3 23.5 30.4 29.7 19.4 14.3 12.8 23.7 19.1 15.8 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 32.6" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB017188: , HPA048389: , HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favourable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 2.5 3.3 3.2 2.2 4.5 3.9 3.1 7.0 5.7 3.2 4.6 2.7 4.4 1.7 2.8 4.1 2.1 4.6 3.5 3.6 3.3 1.6 2.5 2.1 3.8 8.5 3.6 9.2 3.5 2.7 3.0 3.0 2.3 3.3 8.2 3.1 3.1 4.1 4.1 2.3 3.4 3.2 5.6 2.4 3.3 2.3 1.0 1.1 0.5 0.4 0.2 1.1 0.4 5.1 10.1 7.0 2.9 5.9 4.4 2.0 3.7 4.4 4.8 4.6 5.2 0.6 5.1 4.5 6.3 5.2 7.4 3.6 3.5 3.1 4.8 32.6 11.7 1.7 2.2 7.6 2.6 3.7 2.9 5.7 7.1 6.3 12.5 2.1 4.5 2.3 1.7 2.5 2.1 4.4 6.1 10.0 0.4 1.6 11.1 7.8 4.5 8.9 2.5 2.9 3.0 9.0 9.4 8.9 5.8 3.4 5.5 1.4 1.9 4.8 4.1 3.6 4.7 0.0 0.4 0.5 1.1 0.1 0.6 0.5 0.2 0.5 1.1 1.0 0.9 0.5 0.0 0.2 0.3 0.9 0.4 0.4 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592423-88708542 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039170 Approved Approved Cytosol Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favourable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 12.7 13.3 16.9 13.0 27.1 21.0 15.3 37.8 20.1 14.4 12.0 17.9 11.6 11.2 12.0 10.5 16.8 10.7 12.1 22.0 15.2 13.7 15.8 13.0 15.0 15.3 21.9 15.0 12.7 9.7 33.8 16.1 10.0 21.1 22.0 13.4 22.0 14.0 14.0 17.3 19.1 12.8 13.8 16.3 15.7 12.9 3.6 21.5 16.6 15.7 12.6 16.4 13.3 16.7 5.2 7.0 18.2 9.7 3.1 9.0 3.9 7.2 1.1 1.3 2.3 7.7 16.4 4.6 8.2 15.0 8.6 5.7 1.8 8.4 7.7 3.9 27.0 2.5 1.9 7.4 8.2 3.4 2.2 5.3 3.3 1.2 4.4 13.1 9.6 7.8 9.2 8.1 36.8 9.4 3.8 3.4 17.3 2.1 9.0 3.1 0.4 2.0 10.2 9.5 3.1 5.5 1.3 1.9 1.8 9.4 6.0 3.2 1.0 5.9 14.7 9.7 5.3 9.1 6.1 6.4 1.6 4.4 6.1 6.0 4.0 5.7 5.7 7.7 4.7 6.2 5.5 5.2 5.5 4.7 7.0 4.9 8.2 5.8 18.2 3.1 9.7 2.4 9.0 3.9 16.9 27.1 37.8 20.1 15.2 13.7 21.9 15.0 21.1 21.5 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075348 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 55.1;fHDF/TERT166: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: " "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavourable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 25.3 29.4 21.9 28.0 28.4 14.6 22.7 30.5 24.9 24.2 20.5 22.2 26.7 20.0 28.1 24.3 22.2 19.2 20.2 20.5 21.9 22.7 20.6 24.5 20.6 30.2 30.9 14.8 24.5 17.1 25.2 35.6 23.8 26.8 19.4 23.9 17.8 17.7 24.1 19.6 20.9 25.8 23.0 28.7 27.0 17.3 22.2 33.6 23.6 19.5 13.8 28.3 24.7 47.9 7.7 10.4 13.5 9.3 9.9 11.5 6.5 22.4 8.0 5.1 8.5 13.2 18.1 4.6 55.1 34.1 20.7 13.4 4.5 10.6 7.9 4.3 61.8 11.9 5.6 8.1 28.0 5.2 2.7 3.6 13.3 3.5 7.0 4.4 6.5 8.9 9.5 11.0 9.8 12.8 3.8 4.0 31.9 9.6 3.1 5.2 3.0 14.0 4.2 2.1 2.8 9.4 6.4 2.4 2.8 17.9 7.7 7.8 4.8 5.6 17.4 10.9 6.1 26.8 9.4 2.8 3.3 5.0 20.0 8.6 3.7 13.5 9.3 11.1 8.2 7.9 11.5 7.7 9.1 9.8 10.4 7.5 8.8 9.0 11.7 9.9 7.6 2.7 10.6 6.5 21.9 28.4 30.5 24.9 21.9 22.7 30.9 14.8 26.8 33.6 HERC6 FLJ20637 ENSG00000138642 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 6" Q8IVU3 4 88378739-88443111 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 46.0;BJ hTERT+ SV40 Large T+ RasG12V: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035846 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA035846: AB_10673487" "unprognostic (1.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.23e-2)" "unprognostic (2.67e-2)" "unprognostic (8.61e-2)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (5.95e-2)" "unprognostic (1.52e-2)" "unprognostic (6.22e-2)" "prognostic favourable (7.14e-5)" "unprognostic (1.80e-1)" "unprognostic (2.59e-1)" "unprognostic (8.43e-3)" "unprognostic (3.77e-2)" 8.0 7.5 7.8 7.2 10.2 7.3 6.3 2.1 14.6 13.6 6.3 5.9 3.4 5.4 13.2 9.6 23.9 10.4 11.2 9.8 7.7 8.4 10.4 5.0 8.3 4.6 7.3 15.8 9.8 6.3 5.2 8.4 7.1 8.5 9.1 6.5 7.2 28.4 5.7 2.9 4.3 7.1 8.5 5.6 8.0 7.3 3.9 5.3 9.0 5.9 7.6 7.8 7.2 13.8 3.6 2.7 4.5 6.4 5.6 13.4 4.2 2.5 1.7 0.1 0.3 0.1 1.5 0.5 0.3 8.6 46.0 34.3 0.1 3.2 0.0 0.6 0.8 0.9 4.2 2.2 3.0 5.2 0.8 2.4 1.4 0.2 1.5 4.2 1.6 2.1 0.5 3.5 0.1 1.3 0.0 0.5 1.0 1.5 1.9 1.3 0.6 0.8 1.3 0.0 0.1 3.1 3.1 0.1 1.1 3.2 1.0 5.1 1.9 0.7 0.4 0.6 0.8 0.1 0.8 0.1 0.0 0.0 2.1 0.9 2.1 4.4 3.1 4.5 6.7 3.1 13.4 3.6 9.4 6.5 2.7 2.7 7.5 5.1 1.9 5.6 6.4 0.3 11.8 4.2 7.8 10.2 2.1 14.6 7.7 8.4 7.3 15.8 8.5 5.3 HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140455-43202855 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease mutation, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavourable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favourable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" 24.8 16.9 21.4 16.0 18.8 16.0 29.6 18.5 20.6 28.5 17.8 20.3 24.5 15.4 27.5 29.7 20.4 24.0 22.1 18.7 18.0 16.5 16.9 19.9 21.8 14.9 12.9 19.8 31.1 28.8 26.5 24.8 25.6 15.7 21.6 14.7 20.9 20.7 20.7 11.9 29.5 18.1 25.3 18.2 14.9 18.6 8.5 11.7 9.1 21.9 18.4 18.2 21.1 23.2 2.3 14.5 8.3 8.0 8.2 3.1 4.0 11.5 15.6 3.9 7.9 32.3 24.4 5.9 13.2 15.7 9.6 8.6 2.2 17.0 7.0 9.2 18.4 6.7 1.7 8.0 5.6 2.8 3.2 6.9 9.9 3.9 10.4 1.5 1.1 16.3 11.5 5.3 11.1 17.0 3.1 9.9 17.5 5.2 6.2 3.0 3.7 2.3 0.7 7.2 3.4 15.8 9.8 2.1 6.2 17.2 5.5 7.6 19.1 8.9 19.9 14.8 2.5 9.2 5.4 8.0 7.5 2.6 11.9 2.7 9.0 0.2 8.0 8.3 2.8 5.0 3.1 1.8 2.3 2.8 14.5 2.3 1.7 1.9 3.0 8.2 7.2 1.9 1.5 4.0 21.4 18.8 18.5 20.6 18.0 16.5 12.9 19.8 15.7 11.7 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929192-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.1" "Cell line enhanced" "Detected in all" "MCF7: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 15.1 16.8 21.2 14.7 23.0 90.1 13.6 38.1 20.4 20.4 14.4 20.7 14.5 10.2 15.5 14.2 18.7 27.3 17.5 27.9 22.9 17.2 14.8 13.8 19.3 14.7 15.0 16.4 18.7 16.8 20.7 23.8 13.8 21.3 14.4 15.2 20.7 13.0 14.9 19.7 18.5 13.4 15.1 18.3 15.9 14.8 33.5 21.3 47.2 23.3 13.1 15.5 17.3 26.7 2.3 6.2 9.8 4.2 4.3 6.0 2.3 8.1 6.6 9.2 7.0 10.8 5.7 6.2 5.6 6.8 8.0 7.7 7.6 3.1 10.9 7.7 8.9 5.5 11.8 6.6 11.6 7.9 6.0 15.9 8.3 8.0 9.0 12.7 19.7 6.1 9.6 10.2 10.5 11.8 10.8 11.8 11.5 61.5 16.6 7.2 9.4 5.9 10.1 27.0 3.8 7.2 7.0 4.1 5.4 10.2 11.0 7.2 6.4 18.3 11.5 7.9 10.7 12.8 8.5 7.4 5.8 9.5 8.8 10.3 17.9 3.4 4.2 8.2 5.5 3.7 5.2 1.7 4.9 4.9 3.1 2.3 5.0 6.0 9.8 4.3 2.6 6.2 3.6 2.3 21.2 23.0 38.1 20.4 22.9 17.2 15.0 16.4 21.3 21.3 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.1" "Cell line enhanced" "Detected in many" "HDLM-2: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favourable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.6 9.8 58.8 7.4 53.6 14.4 12.6 8.5 39.8 5.5 7.4 54.5 5.2 8.2 4.7 5.2 10.2 9.9 5.5 30.5 60.0 39.9 28.2 17.5 8.6 5.3 66.1 16.4 6.6 12.3 17.2 7.6 10.8 26.4 10.7 5.8 9.4 11.5 7.1 21.6 3.2 6.2 4.8 56.2 7.3 15.4 2.6 38.6 1.7 10.4 2.8 4.9 6.8 7.4 0.6 0.5 17.8 2.9 0.2 1.4 0.5 4.1 18.2 8.4 5.2 20.7 14.8 1.0 2.2 2.2 2.5 2.6 1.3 2.2 0.0 5.3 4.2 0.2 3.8 5.9 6.4 42.0 1.6 18.7 3.0 6.5 11.6 5.1 5.1 22.6 3.9 11.7 17.6 6.3 10.8 5.2 19.5 3.1 6.4 3.7 2.1 12.5 7.7 4.6 0.5 11.6 0.7 5.1 4.7 5.1 0.1 2.6 2.9 2.1 21.2 8.9 4.3 10.3 11.1 25.4 15.1 3.7 18.3 2.7 4.8 17.8 1.1 2.7 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.3 1.4 0.4 1.5 0.2 2.9 0.2 0.0 0.5 58.8 53.6 8.5 25.2 60.0 39.9 66.1 16.4 26.4 38.6 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 46.3 13.4 12.7 15.9 15.9 12.7 49.2 11.7 13.7 23.6 24.8 11.9 15.9 9.9 28.3 22.8 22.9 24.1 18.8 69.0 13.4 11.8 23.4 21.1 20.2 20.9 15.5 8.2 23.6 15.4 49.7 21.2 20.5 15.2 23.2 12.8 15.6 18.8 18.1 45.9 18.7 25.0 32.9 15.9 20.1 20.5 14.7 14.2 15.2 37.9 26.0 14.4 33.6 34.6 3.1 11.3 17.6 10.1 3.3 4.4 3.7 9.4 9.0 6.8 7.7 31.6 20.0 6.8 10.0 11.6 8.1 6.9 9.9 6.9 10.2 8.5 12.2 12.1 5.1 11.2 11.5 14.8 8.0 10.3 10.2 7.5 13.1 11.0 6.5 18.7 22.0 3.1 9.2 9.9 3.2 20.5 13.1 4.9 9.1 7.7 1.7 5.5 12.3 24.2 10.2 13.4 14.8 1.0 5.7 13.6 15.6 9.3 17.5 20.4 12.7 12.8 8.8 14.7 7.1 11.3 17.7 10.8 6.2 11.7 11.9 6.6 10.1 4.8 3.5 7.6 4.4 2.4 3.2 3.7 11.3 3.1 2.9 3.5 17.6 3.3 8.6 1.4 3.2 3.7 12.7 15.9 11.7 13.7 13.4 11.8 15.5 8.2 15.2 14.2 HIPK4 FLJ32818 ENSG00000160396 "Homeodomain interacting protein kinase 4" Q8NE63 19 40379271-40390187 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 34.7" "Cell line enhanced" "Detected in some" "A549: 3.0;AN3-CA: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027733 Uncertain "HPA027733: AB_1850734" "unprognostic (2.07e-2)" "unprognostic (6.25e-2)" "unprognostic (2.58e-2)" "unprognostic (5.53e-3)" "unprognostic (4.00e-2)" "unprognostic (1.36e-1)" "unprognostic (3.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (7.48e-3)" "unprognostic (8.85e-2)" "unprognostic (9.09e-2)" "unprognostic (3.06e-2)" "unprognostic (8.71e-3)" "unprognostic (3.64e-2)" "unprognostic (2.03e-2)" "unprognostic (4.63e-2)" 0.3 0.1 2.3 0.3 7.4 0.2 0.3 1.2 5.7 0.3 0.3 0.3 0.3 0.2 0.4 0.3 0.5 0.2 0.3 0.8 2.9 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.1 0.3 0.4 0.3 1.4 0.2 0.3 0.3 0.3 0.3 0.1 34.7 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.7 0.0 0.4 1.1 0.3 0.1 0.1 3.0 0.2 2.3 0.1 0.3 0.0 0.7 1.1 0.8 0.4 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.5 1.2 0.3 0.3 0.1 0.3 0.0 0.2 0.7 0.1 0.1 0.1 0.4 0.1 0.3 0.3 0.0 0.4 0.0 0.3 0.4 0.1 0.0 0.4 0.1 0.6 1.3 1.2 1.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 2.3 7.4 1.2 3.5 2.9 0.3 0.3 0.3 0.3 0.3 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052, HPA011956" Supported Supported Mitochondria 16000000 Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049, HPA011956: AB_1850758" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavourable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 17.5 10.5 21.1 19.9 30.4 23.5 15.8 40.0 48.6 16.6 16.9 10.1 7.6 6.3 13.5 9.4 44.8 15.2 12.6 61.6 19.8 23.3 10.8 4.4 17.2 14.3 19.8 31.3 9.0 4.6 12.5 14.7 22.6 31.3 25.5 15.4 21.2 21.5 26.8 62.1 30.7 8.6 25.6 9.7 13.3 20.3 28.9 10.6 18.9 33.6 32.6 23.0 25.8 23.1 11.4 25.5 17.8 39.3 8.9 23.0 29.6 17.4 9.9 13.3 12.7 14.9 11.2 8.5 17.4 45.8 23.3 25.2 2.9 1.9 1.2 13.8 29.1 15.3 12.4 38.9 22.3 11.6 9.7 43.4 10.6 0.2 17.0 0.8 32.9 16.9 22.7 33.3 74.5 24.1 72.3 9.2 31.9 28.9 5.0 2.2 20.4 44.3 7.7 8.1 0.1 16.1 20.6 13.7 16.1 19.9 38.7 11.5 21.1 2.8 24.7 34.8 15.9 19.1 24.2 11.0 7.2 3.0 45.1 22.8 10.0 17.8 27.3 13.4 14.0 39.3 23.0 11.4 16.2 15.8 25.5 6.8 14.5 11.5 6.6 8.9 39.3 2.9 17.8 29.6 21.1 30.4 40.0 48.6 19.8 23.3 19.8 31.3 31.3 10.6 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74833981-74893359 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 26.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028587 Enhanced "HPA028587: AB_10602605" "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavourable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 27.0 2.2 4.4 9.5 5.0 20.4 10.8 0.7 4.5 5.3 23.2 7.3 5.7 1.3 2.6 40.1 13.6 4.8 9.1 8.3 2.8 2.3 2.1 1.4 16.5 5.0 8.5 1.1 14.9 3.5 1.1 1.7 13.2 5.4 4.0 19.2 9.6 10.3 0.5 29.3 9.7 8.9 1.7 10.9 7.4 8.7 24.8 7.4 4.3 7.1 22.3 9.2 29.0 8.3 0.8 6.2 26.2 7.1 0.0 0.8 2.0 16.2 0.1 3.8 13.7 32.3 3.4 14.0 6.3 9.2 7.1 10.3 13.0 2.9 11.8 6.1 2.9 5.6 17.2 13.3 20.8 3.3 3.7 16.0 3.7 17.8 10.2 23.3 26.3 5.6 14.5 13.6 23.8 3.4 13.9 0.0 2.0 11.5 5.6 23.9 13.6 11.3 9.2 7.9 9.2 4.3 22.9 2.7 13.4 4.0 20.4 8.0 1.0 3.7 2.7 22.8 4.0 9.4 11.4 8.1 2.3 5.9 53.2 17.1 5.8 6.6 7.1 26.2 0.1 5.7 0.3 0.6 0.4 0.1 6.2 0.8 0.7 0.7 5.9 0.0 3.7 0.1 0.8 2.0 4.4 5.0 0.7 4.5 2.8 2.3 8.5 1.1 5.4 7.4 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899332 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 76.2;bone marrow: 55.0;lymphoid tissue: 40.6" "Cell line enriched" "Detected in some" 4 "U-937: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "basophil: 76.2" "Group enriched" "Detected in many" 11 "granulocytes: 76.2;monocytes: 31.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056743 Enhanced 1700000 "HPA056743: " "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavourable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 9.2 2.6 0.6 8.5 1.0 55.0 1.3 0.3 1.2 0.4 1.7 0.3 0.0 0.9 0.8 2.6 1.9 3.0 0.9 5.4 0.6 0.3 1.6 4.1 16.3 24.1 1.2 0.5 1.2 1.0 0.0 0.4 2.9 0.5 0.9 0.6 0.9 0.9 0.1 0.8 0.3 1.6 3.4 0.6 40.6 1.2 0.6 0.2 1.3 1.5 0.2 1.2 1.8 5.3 0.0 5.1 76.2 31.4 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.6 0.1 0.2 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 20.8 0.0 76.2 15.4 32.9 0.0 29.5 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 5.4 0.0 31.4 0.2 0.0 6.0 0.6 1.0 0.3 1.2 0.6 0.3 1.2 0.5 0.5 0.2 HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220303-69267559 "Enzymes, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 77.4" "Cell line enhanced" "Detected in some" "A549: 14.7;CACO-2: 20.9;CAPAN-2: 41.4;EFO-21: 12.8;Hep G2: 12.1;RPTEC TERT1: 30.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 8.3;T-reg: 6.6" "Lineage enriched" "Detected in single" 29 "T-cells: 8.3" "Region enhanced" "Detected in some" "cerebral cortex: 12.2" "Low region specificity" "Detected in all" "HPA011956, HPA064198, HPA064230" Approved Enhanced Mitochondria Mitochondria "HPA011956: AB_1850758, HPA064198: , HPA064230: " "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" 0.2 0.0 0.9 1.2 1.6 0.0 0.2 0.8 1.4 0.5 29.8 0.5 0.2 29.9 0.5 1.0 0.3 2.5 11.2 0.2 0.5 0.6 15.6 4.6 1.3 0.3 0.3 0.2 1.0 4.7 0.0 0.5 0.2 0.4 0.2 2.3 12.0 0.2 0.2 0.2 0.0 77.4 0.2 0.2 0.2 0.4 0.6 0.2 0.2 5.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.2 8.3 1.6 0.4 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.9 41.4 0.0 12.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.1 1.0 0.0 0.0 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.7 0.0 4.4 1.4 0.0 0.0 8.3 3.2 0.0 0.2 0.0 0.0 6.6 1.6 0.9 1.6 0.8 0.4 0.5 0.6 0.3 0.2 0.4 0.2 HLTF "HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3" ENSG00000071794 "Helicase like transcription factor" Q14527 3 149030127-149086554 "Enzymes, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015284, HPA049001" Uncertain Supported Nucleoplasm Nucleoplasm "HPA015284: AB_1857263, HPA049001: " "unprognostic (3.21e-2)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (1.95e-3)" "unprognostic (4.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavourable (7.27e-4)" "unprognostic (3.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.27e-1)" "unprognostic (4.78e-2)" "unprognostic (9.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (3.42e-1)" "unprognostic (2.83e-2)" "unprognostic (1.07e-2)" 10.2 22.1 12.6 8.4 17.6 9.0 12.4 29.3 23.8 11.1 11.0 12.4 6.2 4.8 12.4 9.6 7.1 10.8 8.6 16.5 15.8 16.6 15.6 16.3 7.1 9.8 15.7 19.0 17.6 12.0 16.5 25.1 7.3 29.9 14.7 7.0 11.3 9.3 11.1 9.7 5.1 6.6 12.7 19.0 7.5 8.7 37.7 14.0 17.1 19.0 4.8 9.6 10.0 7.8 8.4 9.2 8.8 2.3 5.4 10.4 3.5 24.6 12.0 17.1 13.3 11.4 14.9 1.7 16.7 10.0 12.4 14.5 9.7 17.2 15.9 20.4 7.7 0.7 22.9 6.6 20.7 8.7 11.2 38.2 9.4 3.9 7.1 10.0 15.8 9.4 3.6 9.2 5.4 7.1 13.3 10.4 16.9 12.4 20.5 15.4 12.9 15.1 23.7 19.3 2.5 10.2 8.0 16.9 10.0 25.3 11.7 22.9 35.2 9.8 5.0 14.5 8.8 20.5 18.1 15.3 8.6 20.8 14.3 13.7 5.6 8.8 1.3 4.0 5.6 2.1 10.4 8.4 4.9 7.2 3.9 5.4 7.2 7.4 0.2 5.4 2.3 9.2 4.4 3.5 12.6 17.6 29.3 23.8 15.8 16.6 15.7 19.0 29.9 14.0 HMBS "PBGD, PORC, UPS" ENSG00000256269 "Hydroxymethylbilane synthase" P08397 11 119084866-119093549 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006114, HPA050659" Supported Approved "Lipid droplets" 28000000 "Lipid droplets" "HPA006114: AB_1079067, HPA050659: " "unprognostic (6.24e-2)" "unprognostic (9.10e-3)" "unprognostic (1.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (2.29e-3)" "unprognostic (2.81e-1)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (6.83e-2)" "unprognostic (5.06e-2)" "unprognostic (2.90e-3)" "unprognostic (3.91e-3)" "unprognostic (9.53e-2)" "unprognostic (1.32e-1)" "unprognostic (6.11e-2)" 5.5 11.0 5.3 6.2 9.3 75.2 8.6 5.2 8.0 5.5 8.3 6.0 6.0 7.9 6.9 7.9 9.4 5.5 6.4 11.5 5.9 5.5 9.9 22.2 5.8 14.5 8.8 4.5 3.7 21.2 7.9 5.9 9.7 8.4 5.5 9.2 4.1 10.1 7.2 17.4 6.0 7.9 6.8 9.7 10.4 7.1 7.4 7.5 6.0 8.4 13.0 9.3 5.7 4.8 7.7 19.1 12.0 14.0 3.8 7.4 9.4 9.1 14.0 6.7 11.9 5.4 6.7 10.1 7.3 8.3 10.8 9.3 17.3 14.5 14.2 16.4 9.3 13.0 10.0 14.2 6.9 9.7 10.2 23.3 5.6 12.6 9.9 8.7 7.6 7.3 9.1 17.0 13.0 5.0 34.5 6.3 8.5 36.8 8.4 16.8 7.5 8.9 9.7 6.6 13.8 10.8 8.4 7.4 10.1 5.9 9.2 6.4 15.7 12.1 4.6 8.2 6.2 8.0 8.5 3.4 4.0 8.4 5.4 11.5 9.7 12.0 14.0 1.4 5.1 12.2 6.7 7.7 4.8 5.7 19.1 7.2 7.4 5.6 0.4 3.8 7.3 12.3 4.9 9.4 5.3 9.3 5.2 8.0 5.9 5.5 8.8 4.5 8.4 7.5 HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43289395-43313512 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 117.0" "Cell line enhanced" "Detected in all" "AF22: 123.5;HBEC3-KT: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 310000 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: , HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favourable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" 6.0 16.5 13.3 8.1 24.4 4.3 12.8 8.4 38.2 16.9 15.5 16.9 9.5 27.8 6.8 11.5 53.0 4.1 7.5 5.1 19.4 18.8 10.5 117.0 26.9 6.2 10.4 20.7 15.4 8.4 10.8 5.0 6.9 59.3 12.9 14.2 13.0 18.5 7.7 5.0 25.2 17.1 6.3 25.8 4.4 13.4 9.8 8.1 3.3 7.5 58.1 23.3 6.1 21.4 9.3 7.8 6.9 7.7 6.7 7.9 3.3 15.3 7.4 123.5 14.2 7.2 28.7 8.4 2.4 9.7 3.5 7.0 12.8 22.2 16.3 5.5 3.5 12.1 30.7 71.2 3.7 3.4 36.9 6.0 6.8 17.3 11.3 13.1 4.3 15.6 8.6 18.5 7.4 3.6 10.7 44.6 2.9 7.1 11.8 16.0 22.1 3.9 8.5 17.3 18.0 54.7 23.8 10.6 5.1 12.6 6.3 3.7 9.9 17.5 4.3 2.6 13.3 2.8 2.3 6.0 9.1 22.2 2.3 15.8 2.3 5.5 4.0 3.7 5.6 7.4 5.6 9.3 6.2 7.9 7.8 7.5 5.3 7.3 6.9 6.7 7.7 6.5 5.7 3.3 13.3 24.4 8.4 32.1 19.4 18.8 10.4 20.7 59.3 8.1 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119747996-119768905 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 257.0" "Cell line enriched" "Detected in some" 16 "RT4: 66.2" "Cancer enhanced" "Detected in many" "liver cancer: 441.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Supported Mitochondria 820000 Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favourable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favourable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favourable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 0.3 0.1 0.3 8.7 0.3 0.0 20.6 0.3 0.3 0.3 30.8 0.4 0.3 13.8 0.3 0.3 0.7 0.1 4.4 42.0 0.4 0.0 7.4 257.0 0.8 0.3 0.3 0.3 0.3 1.4 0.0 0.3 0.8 0.7 3.8 19.8 18.9 5.1 0.3 1.4 1.8 12.2 1.9 0.3 0.3 8.1 6.1 0.3 0.4 0.3 0.6 2.1 7.4 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 66.2 0.0 0.2 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.4 0.0 0.3 0.3 0.7 0.3 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 61.3;HSkMC: 25.1;RT4: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 34.6;intermediate monocyte: 26.7;myeloid DC: 20.9;non-classical monocyte: 14.6" "Group enriched" "Detected in many" 22 "dendritic cells: 20.9;monocytes: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol 64000 "Nucleoplasm, Cytosol" Centrosome "HPA035480: , HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favourable (4.68e-4)" 41.4 5.8 12.2 12.3 11.1 3.3 28.8 10.7 11.3 27.6 16.3 8.6 13.9 8.7 22.2 21.4 11.6 14.6 21.6 14.7 12.7 7.8 33.4 74.2 21.9 17.0 13.7 9.2 33.1 14.1 24.5 5.5 14.3 11.2 22.3 17.7 8.7 14.1 20.1 4.9 8.1 11.1 13.2 14.8 18.5 11.5 11.7 14.6 1.0 7.3 8.5 6.5 21.3 12.0 0.5 20.9 1.2 34.6 0.1 0.2 9.2 0.2 0.3 1.5 4.1 17.6 18.9 0.1 1.1 1.7 0.1 0.7 7.8 4.4 0.2 13.9 4.6 0.4 3.2 0.0 0.0 0.2 1.6 0.1 13.1 61.3 7.9 0.0 0.2 25.1 0.0 6.2 0.0 4.4 0.2 0.3 13.2 1.0 0.0 0.2 7.8 1.6 0.1 0.5 0.0 18.9 31.8 0.1 0.4 6.0 7.7 0.0 0.2 14.4 1.3 1.3 3.4 1.8 4.4 0.1 0.0 0.2 6.0 7.5 0.9 0.8 34.6 0.2 0.2 26.7 0.1 0.5 0.1 0.1 20.9 0.3 0.1 0.2 1.2 0.1 14.6 0.6 0.2 9.2 12.2 11.1 10.7 11.3 12.7 7.8 13.7 9.2 11.2 14.6 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 24.8" "Group enriched" "Detected in some" 8 "HEL: 31.6;HMC-1: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 15.8" "Lineage enriched" "Detected in single" 25 "granulocytes: 15.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol 170000 "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 14.3 2.9 8.0 1.6 12.1 1.6 5.8 2.0 7.7 5.4 6.9 4.4 0.2 7.5 4.7 3.3 4.1 2.5 9.3 3.0 8.4 3.6 2.5 1.3 12.7 0.9 9.6 2.4 1.5 1.8 1.7 1.5 24.8 9.0 6.4 7.5 2.9 3.8 2.2 1.4 5.8 8.6 5.8 14.6 1.4 4.4 1.8 12.1 1.5 1.2 2.8 1.5 4.5 3.5 0.0 0.1 15.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 2.4 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 8.0 12.1 2.0 7.7 8.4 3.6 9.6 2.4 9.0 12.1 HPRT1 "HGPRT, HPRT" ENSG00000165704 "Hypoxanthine phosphoribosyltransferase 1" P00492 X 134460153-134520513 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease mutation, FDA approved drug targets, Gout" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006360, CAB012200" Enhanced Supported Cytosol 15000000 Cytosol "CAB012200: AB_297217, HPA006360: AB_1079082" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.46e-1)" "unprognostic (2.32e-3)" "unprognostic (8.55e-2)" "prognostic unfavourable (1.35e-5)" "unprognostic (1.58e-2)" "unprognostic (4.77e-3)" "unprognostic (4.93e-2)" "unprognostic (2.02e-2)" "unprognostic (7.05e-2)" "unprognostic (1.38e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" 7.9 14.9 31.0 12.6 30.2 25.3 11.3 24.2 49.8 7.5 13.7 5.8 9.8 11.0 7.9 36.2 10.3 9.4 8.1 12.8 27.6 37.3 18.4 24.7 7.3 15.9 23.5 28.9 9.8 20.2 9.9 18.6 8.8 34.4 8.8 13.2 9.7 7.1 9.5 10.7 8.0 14.2 9.5 9.8 8.7 17.1 39.7 4.9 13.7 12.3 8.6 15.9 10.8 7.5 13.5 19.7 10.1 18.5 19.9 29.3 12.6 31.0 15.0 4.2 8.7 9.5 13.7 12.8 16.6 16.0 21.3 28.0 13.4 19.9 35.2 37.9 10.8 19.1 27.4 22.8 36.8 29.2 51.3 19.1 21.3 13.6 9.4 41.0 17.6 10.1 8.6 18.9 30.3 24.5 14.6 0.9 16.6 31.7 31.6 35.6 8.7 40.3 19.0 21.6 36.1 25.6 15.1 26.9 14.7 12.0 9.7 11.3 8.3 17.2 12.1 14.5 10.9 41.4 41.2 13.4 23.2 0.2 17.8 45.6 7.9 2.2 11.6 10.1 11.6 18.5 16.7 12.3 17.3 15.3 19.7 13.5 14.3 15.1 2.9 19.9 17.2 8.2 29.3 12.6 31.0 30.2 24.2 49.8 27.6 37.3 23.5 28.9 34.4 4.9 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429765 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.4;gallbladder: 31.9;ovary: 30.3" "Cell line enhanced" "Detected in some" "A-431: 4.4;CAPAN-2: 14.0;HaCaT: 4.2;RPTEC TERT1: 12.4;RT4: 10.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "cerebellum: 27.4;cerebral cortex: 9.0" "Group enriched" "Detected in some" 39 "memory B-cell: 7.3;naive B-cell: 15.8;plasmacytoid DC: 22.3" "Group enriched" "Detected in many" 99 "B-cells: 15.8;dendritic cells: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favourable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favourable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favourable (8.67e-4)" 2.3 2.9 1.6 2.8 2.2 2.8 2.0 27.4 9.0 3.3 2.7 1.1 3.6 3.5 4.3 5.0 10.2 4.3 31.9 2.2 1.7 1.8 10.4 0.9 3.4 2.1 1.9 1.5 30.3 1.1 0.7 8.9 1.0 2.4 3.2 1.7 1.7 3.7 2.4 0.7 0.8 2.9 1.7 2.2 3.0 7.0 3.0 0.3 3.8 1.8 7.0 7.4 7.3 2.4 15.8 22.3 0.1 0.1 0.0 0.1 0.6 4.4 0.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.0 0.0 0.4 0.0 4.2 0.0 2.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.9 1.1 1.0 0.0 0.0 12.4 10.1 3.7 0.0 0.0 0.1 0.5 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 7.3 0.0 0.0 0.3 15.8 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.6 1.6 2.2 27.4 9.0 1.7 1.8 1.9 1.5 2.4 0.3 HS3ST2 3OST2 ENSG00000122254 "Heparan sulfate-glucosamine 3-sulfotransferase 2" Q9Y278 16 22814177-22916338 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 12.7;brain: 38.2;lung: 13.4" "Group enriched" "Detected in some" 5 "HaCaT: 10.2;SH-SY5Y: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017736 Approved "HPA017736: AB_1851095" "unprognostic (4.09e-2)" "unprognostic (2.90e-3)" "unprognostic (5.97e-3)" "unprognostic (3.46e-3)" "prognostic unfavourable (1.57e-4)" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-1)" "unprognostic (2.75e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "prognostic favourable (1.35e-4)" "unprognostic (4.89e-2)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (3.00e-2)" 12.7 1.7 3.8 1.1 6.5 1.1 2.4 0.5 38.2 2.0 1.4 0.3 0.3 1.0 1.0 1.0 1.2 1.0 1.1 3.8 7.8 4.3 1.0 2.2 13.4 2.1 2.2 8.4 4.5 1.0 1.0 0.4 1.2 1.5 2.0 1.4 5.0 2.9 1.1 1.0 2.0 1.0 1.2 1.0 1.1 1.1 1.1 0.0 0.0 1.8 0.4 1.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 6.5 0.5 19.1 7.8 4.3 2.2 8.4 1.5 0.0 HS3ST3A1 "30ST3A1, 3OST3A1" ENSG00000153976 "Heparan sulfate-glucosamine 3-sulfotransferase 3A1" Q9Y663 17 13495689-13601927 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 16.9;U-251 MG: 46.9;U-87 MG: 29.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 1.0;cerebral cortex: 2.2;pons and medulla: 3.0" "Cell type enhanced" "Detected in many" "T-reg: 5.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.9;T-cells: 5.1" "HPA062518, HPA071530" Uncertain Approved Microtubules Microtubules "HPA062518: , HPA071530: " "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (8.35e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-3)" "unprognostic (4.44e-2)" "unprognostic (2.01e-1)" "unprognostic (4.46e-3)" "unprognostic (2.12e-4)" "unprognostic (1.12e-2)" "unprognostic (8.52e-2)" "unprognostic (1.55e-1)" "unprognostic (1.85e-9)" "unprognostic (1.83e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (4.70e-3)" 1.3 3.3 0.2 2.8 1.0 1.5 2.3 0.1 2.2 7.8 1.6 0.3 5.8 2.3 3.3 1.3 8.1 1.9 1.3 3.8 0.3 0.2 1.7 3.4 2.2 9.3 0.1 0.4 12.1 0.4 0.0 1.2 6.8 3.0 9.9 0.5 2.0 3.3 8.6 0.9 1.1 1.7 0.4 1.3 11.7 1.0 2.9 0.0 0.6 0.6 6.3 12.7 1.4 5.3 0.1 3.9 0.5 0.1 0.7 5.1 0.8 0.0 0.1 1.1 0.0 0.8 2.2 2.0 7.5 1.6 1.2 0.8 0.0 0.2 0.0 1.0 4.1 0.0 0.0 0.0 1.0 0.4 7.7 1.9 0.5 0.7 0.6 0.0 0.5 1.9 0.0 3.3 0.7 0.0 7.4 0.0 1.3 0.9 0.0 1.3 1.4 16.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.0 46.9 0.0 0.0 0.0 29.1 0.0 3.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 1.2 1.4 0.0 0.1 1.4 1.4 0.5 0.7 0.1 3.9 5.1 0.8 0.2 1.0 0.1 2.2 0.3 0.2 0.1 0.4 3.0 0.0 HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301083-14349404 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 20.6;liver: 29.1;lymphoid tissue: 26.6;placenta: 33.5;salivary gland: 12.6" "Cell line enhanced" "Detected in many" "AF22: 15.2;BEWO: 10.9;Hep G2: 13.2;HSkMC: 15.1;U-251 MG: 13.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.7;pons and medulla: 6.0" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 20.6" "Group enriched" "Detected in many" 5 "dendritic cells: 20.6;T-cells: 14.7" HPA064126 Approved Vesicles Vesicles "HPA064126: " "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (2.85e-3)" "unprognostic (5.22e-2)" "unprognostic (5.03e-3)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (8.13e-3)" "unprognostic (8.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-3)" "unprognostic (7.77e-3)" "unprognostic (9.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-3)" 1.4 1.4 0.6 8.7 0.8 1.3 3.0 0.9 2.7 3.8 1.8 0.0 0.8 1.4 1.0 0.3 2.8 1.7 2.6 2.0 0.6 0.7 3.6 29.1 3.7 26.6 0.6 0.0 4.7 1.3 0.4 1.4 33.5 6.0 2.4 1.9 5.3 12.6 2.5 1.8 2.2 2.5 0.6 2.9 4.9 1.4 0.7 0.0 13.2 1.5 2.5 5.9 1.5 5.3 0.4 20.6 0.5 0.4 3.8 14.7 2.7 0.0 0.3 15.2 0.0 4.6 5.2 10.9 4.3 6.3 3.9 4.1 0.0 0.1 0.0 0.0 5.9 0.0 0.4 2.4 2.0 1.2 3.1 0.3 2.0 13.2 6.0 0.5 2.3 15.1 0.8 1.3 3.6 0.0 4.5 0.0 3.1 0.8 0.7 0.6 0.5 0.4 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 3.8 0.0 0.0 13.9 0.0 0.0 0.0 3.0 0.0 0.9 0.1 0.2 0.0 6.3 0.4 5.0 0.4 7.6 4.9 0.4 0.4 7.7 7.5 0.5 3.8 0.4 20.6 14.7 2.7 0.6 0.8 0.9 2.7 0.6 0.7 0.6 0.0 6.0 0.0 HS3ST4 3OST4 ENSG00000182601 "Heparan sulfate-glucosamine 3-sulfotransferase 4" Q9Y661 16 25692026-26137688 "Enzymes, Predicted membrane proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 23.9" "Group enriched" "Detected in some" 4 "NTERA-2: 5.4;SCLC-21H: 2.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "unprognostic (1.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (1.43e-3)" "unprognostic (1.27e-1)" "unprognostic (3.84e-1)" "unprognostic (8.81e-3)" "unprognostic (6.71e-2)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (3.67e-2)" 0.7 0.8 6.9 0.6 9.3 0.6 5.1 6.8 23.9 1.1 0.6 2.6 0.0 0.6 0.7 1.3 0.9 0.7 0.6 0.6 11.5 10.0 0.7 0.6 0.6 0.6 5.9 10.8 0.7 0.6 0.6 0.1 0.6 14.3 2.0 0.6 0.3 0.8 0.6 0.6 0.7 0.6 0.6 2.2 3.7 1.1 1.3 1.5 0.0 0.6 0.0 0.8 1.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 9.3 6.8 13.4 11.5 10.0 5.9 10.8 14.3 1.5 HS3ST5 3-OST-5 ENSG00000249853 "Heparan sulfate-glucosamine 3-sulfotransferase 5" Q8IZT8 6 114055586-114343045 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;seminal vesicle: 9.4;skeletal muscle: 10.1" "Cell line enhanced" "Detected in some" "PC-3: 4.9;RT4: 9.0;SCLC-21H: 17.5;U-266/70: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021823, HPA064677" Approved "HPA021823: AB_1851100, HPA064677: AB_2685318" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-2)" "unprognostic (1.04e-2)" "unprognostic (1.72e-2)" "unprognostic (3.00e-2)" "unprognostic (7.98e-4)" "unprognostic (5.39e-2)" "unprognostic (6.29e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.53e-2)" 0.5 1.9 3.3 0.9 13.1 1.3 0.5 0.6 11.9 0.8 1.0 9.1 3.5 0.7 0.8 0.5 0.6 0.6 0.7 0.5 4.2 3.5 0.9 0.5 1.1 0.5 6.1 2.7 0.6 1.3 0.5 0.3 0.6 7.8 0.7 0.9 0.6 0.7 9.4 10.1 1.3 1.2 0.9 7.5 0.5 1.2 0.9 8.0 0.0 0.6 0.0 0.5 2.5 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 4.9 0.0 1.0 0.0 0.0 9.0 17.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 4.4 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.3 13.1 0.6 5.7 4.2 3.5 6.1 2.7 7.8 8.0 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911463-1918440 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.8;skin 1: 15.0" "Group enriched" "Detected in some" 5 "A549: 2.8;HaCaT: 2.7;U-2 OS: 1.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "unprognostic (5.72e-2)" "prognostic favourable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.1 0.1 6.6 0.4 0.0 0.4 0.0 0.3 0.9 18.8 1.2 0.0 0.1 0.1 0.1 0.2 0.1 1.9 0.1 0.1 0.0 0.5 0.1 0.0 0.2 1.9 0.0 3.6 0.0 0.6 0.4 0.1 0.3 15.0 0.1 1.0 0.1 0.1 0.1 0.1 0.0 2.1 0.1 2.7 3.2 6.7 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.4;BEWO: 12.9;RH-30: 14.2;SCLC-21H: 11.6;SiHa: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA027295: , HPA027372: " "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favourable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.4 0.1 0.0 0.0 12.9 1.0 0.0 0.2 0.0 4.1 0.1 0.0 0.4 4.8 0.0 6.2 0.0 0.0 0.0 3.1 0.0 2.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.9 7.9 0.1 0.1 14.2 0.0 1.1 0.0 11.6 7.7 10.2 0.8 0.4 4.2 1.1 0.0 0.0 7.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 4.9 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase" Q7Z6Z7 X 53532096-53686729 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol 3400 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 24.6 28.2 27.7 23.8 43.3 22.4 28.0 37.0 41.1 31.8 25.9 34.3 26.6 17.1 31.9 52.4 27.4 26.5 23.1 27.1 28.0 31.8 30.3 26.2 20.3 23.1 30.0 30.2 43.3 27.8 59.8 34.2 27.2 34.6 27.3 22.7 25.6 26.4 29.6 59.1 50.1 22.1 33.9 23.9 26.6 25.7 28.4 27.7 32.4 27.6 20.7 28.6 27.0 22.9 5.1 7.2 8.2 7.0 6.9 8.9 3.5 50.1 30.9 20.1 14.2 35.3 21.1 24.8 15.1 19.5 15.9 16.7 23.5 16.2 26.3 10.3 27.4 24.1 45.4 25.3 21.8 37.9 20.1 20.9 27.7 18.3 32.5 31.3 12.9 20.1 19.0 38.2 43.9 27.5 20.8 17.1 20.6 30.9 16.9 17.5 27.5 22.3 15.7 27.8 15.9 26.4 34.8 16.8 12.1 42.6 19.0 13.6 27.2 15.2 35.0 14.7 21.1 20.9 19.2 15.0 14.7 23.0 15.7 30.7 21.1 4.0 4.7 8.2 7.2 3.8 8.9 5.1 6.9 7.6 6.7 5.1 4.9 4.9 4.2 6.9 7.0 7.2 5.7 3.5 27.7 43.3 37.0 41.1 28.0 31.8 30.0 30.2 34.6 27.7 HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 17.5;U-266/84: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 7.1" "Lineage enriched" "Detected in single" 8 "T-cells: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040706 Approved Approved Vesicles,Aggresome Vesicles Aggresome "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" 6.3 7.5 6.4 4.8 8.0 1.7 7.7 2.3 6.1 8.2 14.3 2.5 6.8 11.1 6.4 11.0 7.0 6.5 7.5 8.5 4.3 3.5 19.4 10.5 3.6 4.3 3.5 3.6 9.7 15.5 4.0 8.8 1.5 4.3 8.0 6.2 10.1 7.9 10.1 8.9 3.9 21.2 9.4 3.4 1.6 6.8 7.8 2.2 5.7 7.3 3.7 4.1 7.1 5.1 0.4 0.6 0.8 0.2 0.5 7.1 1.2 3.1 5.1 0.5 9.0 2.0 4.4 1.9 1.0 2.1 3.0 3.5 1.7 3.7 2.5 1.1 2.0 3.6 8.2 2.7 2.8 1.1 17.5 1.1 2.2 4.2 5.1 0.3 1.4 4.0 5.1 1.1 2.3 2.1 3.0 6.5 1.7 3.8 2.9 0.5 0.5 6.5 1.7 9.9 2.0 5.6 3.5 0.9 1.2 2.2 6.7 7.9 7.6 0.2 0.9 1.9 1.4 3.6 3.3 10.2 17.8 0.1 2.2 0.1 2.7 0.8 0.2 0.5 0.3 0.1 0.4 0.4 2.4 0.4 0.1 0.4 7.1 1.3 0.8 0.5 0.1 0.6 1.0 1.2 6.4 8.0 2.3 6.1 4.3 3.5 3.5 3.6 4.3 2.2 ICK "KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Intestinal cell kinase" Q9UPZ9 6 53001279-53061802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Approved "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA000791: , HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 9.8 28.2 10.1 6.5 10.7 2.8 13.4 14.3 12.7 11.5 12.3 20.1 6.6 11.3 10.6 6.8 10.4 9.2 8.3 9.6 10.8 7.7 5.4 9.6 8.2 5.5 13.3 8.1 11.8 8.2 9.0 5.3 44.3 12.3 12.2 13.0 9.7 20.7 12.7 5.9 10.1 14.2 13.7 16.8 6.2 15.0 5.6 12.6 14.8 7.6 7.0 7.9 10.6 9.1 4.5 4.1 6.2 3.1 3.2 5.0 2.1 5.2 2.0 10.3 7.0 6.4 10.1 11.9 4.7 8.6 7.6 8.7 2.8 1.7 3.8 2.8 14.3 3.5 12.2 4.9 10.1 13.2 4.8 2.9 2.4 15.0 3.2 3.5 3.8 9.0 5.3 3.2 3.7 7.1 5.4 15.8 17.3 4.5 3.7 4.3 3.9 4.3 5.9 4.5 5.1 3.1 3.8 16.6 7.4 4.6 11.4 6.5 6.6 7.4 5.8 12.2 5.7 4.5 11.6 4.4 3.1 1.5 2.5 3.4 5.9 6.2 3.1 5.6 5.0 2.3 4.8 3.7 3.6 4.1 2.9 4.5 4.2 3.6 1.7 3.2 2.5 4.1 4.8 2.1 10.1 10.7 14.3 12.7 10.8 7.7 13.3 8.1 12.3 12.6 ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 126.5" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" 19.0 20.9 11.2 11.4 22.6 3.2 37.4 20.1 19.8 19.8 16.6 12.9 13.3 17.3 18.0 19.7 19.0 15.1 17.7 28.5 11.5 10.3 23.5 14.5 17.2 13.9 13.9 8.4 8.7 20.2 26.2 24.0 20.3 12.7 16.2 16.0 21.5 15.4 18.2 41.3 16.9 22.8 19.8 11.1 11.3 13.5 9.1 7.8 13.0 18.1 30.3 17.2 15.4 13.6 4.1 6.2 4.1 5.1 4.6 7.4 3.9 12.5 11.7 16.1 15.7 49.4 19.7 6.9 30.3 20.4 18.0 13.8 12.5 10.2 13.8 11.6 23.9 17.1 18.3 12.8 19.2 27.4 17.7 9.4 17.2 9.5 9.7 14.8 13.4 12.6 8.6 18.9 7.2 14.0 9.1 10.9 20.3 7.9 14.8 10.3 10.8 16.3 12.5 22.7 8.0 21.7 9.3 21.9 10.7 14.9 35.3 12.9 9.2 12.5 17.3 20.6 8.1 24.0 21.7 10.2 19.7 11.0 10.1 34.4 10.6 4.1 4.2 3.6 7.4 5.1 6.5 2.7 6.0 7.3 3.9 4.1 5.4 4.5 1.8 4.6 4.0 6.2 3.4 3.9 11.2 22.6 20.1 19.8 11.5 10.3 13.9 8.4 12.7 7.8 IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK, gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 35.9;liver: 39.1" "Cell line enhanced" "Detected in many" "MCF7: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: " "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favourable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" 4.3 6.1 9.4 2.9 20.3 2.2 4.5 12.3 8.3 2.3 11.3 7.0 3.1 14.2 2.5 7.4 4.1 6.8 4.5 2.8 7.6 8.6 27.2 39.1 3.7 4.7 7.3 6.3 3.2 6.6 3.6 5.2 1.8 6.2 4.2 4.7 5.2 4.6 5.0 1.2 3.3 20.2 3.5 7.0 4.2 4.3 2.0 6.8 14.5 7.0 1.2 4.3 2.8 2.1 17.5 9.6 35.9 20.5 15.0 23.0 11.4 3.4 8.4 1.1 1.3 3.8 5.5 6.1 2.4 7.0 2.6 2.1 2.2 3.1 4.4 4.1 3.7 5.9 0.9 1.6 2.8 9.6 1.0 1.6 3.3 9.6 16.7 1.0 2.0 3.7 2.2 5.8 5.5 6.0 1.3 4.6 3.9 19.3 2.7 1.1 1.0 3.8 3.3 3.2 2.5 7.0 4.0 5.4 6.9 5.6 4.4 5.9 4.4 5.9 6.1 1.2 0.8 10.9 4.5 6.8 7.8 0.6 6.0 1.8 2.1 35.9 6.1 8.6 14.7 10.6 12.3 17.5 12.7 12.1 8.5 11.4 10.2 13.8 1.1 15.0 20.5 9.6 23.0 11.4 9.4 20.3 12.3 8.3 7.6 8.6 7.3 6.3 6.2 6.8 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648971-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.7" "Group enriched" "Detected in many" 5 "granulocytes: 7.7;T-cells: 2.9" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved Approved Vesicles 36000 Vesicles "CAB010268: AB_671792, HPA045563: " "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 8.4 12.7 11.5 5.9 13.5 16.3 18.5 23.0 15.7 15.3 13.4 10.4 22.7 4.2 15.3 16.3 9.2 18.9 7.7 11.6 11.7 7.3 17.0 2.0 11.0 4.9 8.0 11.8 23.2 22.5 4.7 13.8 17.5 9.5 21.7 7.2 16.7 12.5 23.2 9.1 13.0 7.5 18.1 8.0 7.3 10.7 12.0 11.5 10.7 16.1 7.0 5.6 12.8 21.6 1.0 0.4 7.7 0.6 1.0 2.9 0.7 3.3 16.5 11.6 0.2 5.8 4.2 7.7 3.7 7.4 1.2 1.1 7.1 8.8 0.8 10.7 7.2 15.8 5.1 15.0 1.0 0.0 5.2 12.5 18.5 14.2 5.1 6.6 1.3 6.6 7.1 2.1 10.2 4.1 0.6 2.9 5.7 23.4 2.5 4.4 10.8 0.9 4.0 9.0 3.0 3.5 20.3 3.9 17.3 26.7 1.5 14.4 8.1 3.1 11.3 1.1 15.0 3.0 5.8 1.0 4.4 2.7 2.2 4.9 2.8 4.0 0.6 1.8 0.9 0.6 0.6 0.4 0.8 0.3 0.4 1.0 2.9 1.0 7.7 1.0 0.5 0.3 0.0 0.7 11.5 13.5 23.0 15.7 11.7 7.3 8.0 11.8 9.5 11.5 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332653 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Approved Cytosol Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favourable (1.46e-6)" 9.1 10.8 10.9 17.0 16.7 9.3 10.0 26.1 16.9 10.3 10.3 12.4 11.4 4.7 15.3 13.2 17.9 16.4 14.9 7.9 13.1 6.9 12.4 9.9 14.9 12.2 20.3 7.9 9.6 13.3 18.0 13.6 11.2 11.9 14.0 10.9 10.5 11.4 9.7 17.6 22.2 9.8 16.4 10.5 18.7 10.8 8.3 18.6 12.9 14.3 8.4 17.1 18.1 12.8 12.6 14.8 14.1 9.6 11.9 11.2 5.8 3.6 13.1 3.7 6.4 14.5 12.6 4.8 3.2 11.5 9.7 8.5 3.0 6.8 7.2 5.6 8.9 4.2 5.1 13.0 12.5 7.0 5.8 10.1 6.1 2.3 11.1 1.9 10.6 8.4 9.9 9.3 14.4 14.3 8.5 3.5 21.2 4.2 7.0 3.2 3.6 4.1 7.2 6.4 4.2 10.9 3.3 1.1 2.1 2.1 3.6 5.3 4.8 8.5 7.4 6.8 3.6 5.3 2.3 2.1 2.2 5.1 8.1 4.8 7.7 14.1 9.6 10.4 10.1 7.6 10.3 9.4 10.5 11.2 8.9 12.6 10.2 10.4 11.4 11.9 9.0 14.8 9.9 5.8 10.9 16.7 26.1 16.9 13.1 6.9 20.3 7.9 11.9 18.6 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 19.5" "Cell line enhanced" "Detected in many" "NB-4: 25.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.1 0.9 1.0 17.3 3.4 4.3 1.4 1.1 1.7 2.2 4.8 1.5 1.7 3.9 2.0 3.9 6.1 1.2 3.6 1.1 2.9 1.5 0.6 3.7 13.6 2.1 0.7 1.0 1.5 0.0 0.8 2.5 1.9 1.8 4.3 1.5 8.3 2.9 0.1 8.9 4.2 1.0 2.9 12.8 4.0 0.0 2.4 18.8 2.6 4.4 19.5 4.4 0.4 12.9 4.6 4.2 15.9 10.8 24.8 12.3 8.8 7.0 1.9 0.2 3.5 5.0 2.0 3.6 11.3 4.9 5.5 5.5 14.4 17.5 9.7 7.2 12.0 0.0 9.1 1.0 2.8 1.7 2.4 4.2 3.8 4.6 14.9 8.0 6.5 1.6 4.0 0.8 7.1 1.1 5.4 5.1 1.8 9.5 25.1 2.8 5.4 5.1 2.1 14.0 5.8 15.1 0.0 0.0 1.5 12.0 2.2 7.2 10.6 13.7 4.9 3.0 3.5 4.0 1.8 0.8 11.4 9.2 12.5 2.0 4.2 15.9 0.3 10.5 11.2 7.5 12.9 16.7 15.2 4.6 7.4 13.3 13.6 1.1 10.8 6.4 1.5 24.8 12.3 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Cell Junctions,Focal adhesion sites" 130000000 "Cell Junctions, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: " "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favourable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 20.9 17.6 11.0 22.3 11.9 7.5 37.0 9.4 14.6 40.2 75.1 14.7 41.9 13.5 75.4 25.2 35.7 33.2 41.1 35.1 11.1 9.2 21.6 15.1 21.9 18.9 11.5 14.0 24.2 22.3 20.4 10.9 22.2 11.5 39.9 24.6 19.3 19.4 89.9 18.5 12.4 22.2 103.5 10.6 20.2 33.2 14.2 11.0 8.2 17.5 14.1 13.6 60.8 25.9 19.5 45.9 76.5 49.4 45.3 25.8 63.7 23.8 18.4 29.1 10.0 44.9 31.9 13.2 35.1 69.4 41.6 50.8 19.2 28.1 9.0 9.3 57.4 19.2 16.2 29.7 41.8 15.7 14.8 12.9 17.6 14.9 30.1 10.3 14.8 30.6 14.0 28.1 21.5 39.6 11.8 10.7 54.2 17.9 9.1 17.7 18.3 21.6 9.6 15.2 9.5 30.5 19.1 5.0 11.4 16.6 23.0 19.3 16.0 11.8 45.8 52.2 23.6 21.6 17.0 7.8 4.8 12.6 38.7 15.6 24.3 48.3 49.4 76.5 25.8 47.9 25.1 19.5 23.3 24.4 45.9 17.1 14.7 18.5 31.7 45.3 44.4 18.5 25.7 63.7 11.0 11.9 9.4 14.6 11.1 9.2 11.5 14.0 11.5 11.0 INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 73.5" "Group enriched" "Detected in some" 5 "CACO-2: 18.2;HHSteC: 7.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.2" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA061343 Approved "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA061343: " "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (5.26e-2)" "unprognostic (6.78e-3)" "unprognostic (1.59e-1)" "unprognostic (3.39e-4)" "prognostic favourable (5.72e-4)" "unprognostic (3.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (9.07e-2)" "unprognostic (4.97e-2)" "unprognostic (1.62e-2)" "unprognostic (1.43e-2)" "unprognostic (9.71e-2)" "unprognostic (1.58e-2)" 19.7 18.0 0.3 3.0 0.7 0.0 5.9 0.3 0.6 4.9 3.7 1.3 14.0 0.8 9.8 18.9 12.4 16.3 14.7 24.6 0.6 0.4 11.8 24.3 73.5 12.1 1.1 0.8 20.2 4.0 0.7 3.2 12.9 2.5 10.1 1.6 13.0 6.1 19.9 4.7 1.5 3.9 11.3 1.3 6.5 5.0 28.2 0.2 0.5 9.4 3.8 2.8 9.6 6.4 1.7 1.1 4.2 1.0 2.2 1.0 0.6 0.0 0.1 0.1 0.1 1.8 2.5 0.4 0.2 2.3 0.0 0.0 18.2 0.1 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 7.8 0.1 0.3 0.9 0.0 0.0 0.1 0.4 0.1 0.3 0.3 0.1 0.0 0.4 0.8 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.1 0.7 0.0 0.2 0.1 1.1 0.1 0.8 0.3 0.1 0.8 0.3 0.1 0.2 0.1 0.3 4.2 1.0 0.8 0.7 0.4 0.7 1.2 0.7 0.6 0.4 1.7 1.0 0.8 3.0 2.2 0.4 1.1 0.6 0.6 0.3 0.7 0.3 0.6 0.6 0.4 1.1 0.8 2.5 0.2 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294034 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5" "Cell line enhanced" "Detected in many" "Karpas-707: 30.6;U-266/70: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 8.8;granulocytes: 5.1;monocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" 72000 Vesicles "Plasma membrane" "HPA036302: , HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.9 14.7 7.1 3.5 8.2 4.5 12.0 12.0 8.2 10.3 15.2 11.7 10.6 8.4 15.5 6.1 4.7 13.1 7.7 17.7 6.4 5.8 18.7 32.5 5.3 2.2 10.1 4.9 28.3 64.5 11.6 11.6 26.2 8.0 10.5 8.9 11.0 12.0 10.6 15.1 7.3 16.0 10.6 6.8 47.3 8.7 6.9 9.7 2.2 17.1 5.0 3.2 11.3 16.0 1.1 8.8 5.1 10.5 0.8 0.7 1.3 3.7 2.1 1.9 2.9 10.6 3.7 6.4 2.1 1.9 1.2 1.2 5.3 4.3 4.7 5.3 3.8 1.0 4.6 0.9 0.7 0.0 3.7 0.0 1.5 11.5 4.6 2.2 3.8 5.7 2.4 0.1 2.8 2.1 5.7 30.6 0.9 1.7 1.6 3.8 1.8 3.3 16.3 1.1 4.1 0.1 15.5 3.7 2.8 3.8 2.0 2.1 0.9 10.8 2.0 2.2 1.4 4.7 2.8 22.6 12.3 10.9 2.6 3.8 0.0 2.0 8.2 5.1 0.2 7.8 0.3 0.8 0.3 0.1 8.8 1.1 0.7 0.1 1.7 0.8 10.5 7.4 0.0 1.3 7.1 8.2 12.0 8.2 6.4 5.8 10.1 4.9 8.0 9.7 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859018 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.5;brain: 5.9;kidney: 8.3" "Group enriched" "Detected in some" 7 "SCLC-21H: 5.4;SH-SY5Y: 18.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA025285 Uncertain "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.9 5.5 0.0 0.3 5.9 0.1 0.8 1.9 1.4 1.9 0.1 0.0 0.0 0.1 2.7 0.1 0.1 0.6 0.3 1.9 0.5 1.3 8.3 0.1 0.1 0.4 0.8 0.6 0.3 0.9 0.1 1.7 0.4 5.6 2.7 0.1 2.1 0.6 0.5 0.4 0.1 0.2 0.3 0.0 0.2 3.0 4.2 0.4 0.3 0.3 0.0 0.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 1.4 0.5 1.3 0.8 0.6 5.6 0.4 IP6K1 "IHPK1, KIAA0263" ENSG00000176095 "Inositol hexakisphosphate kinase 1" Q92551 3 49724294-49786542 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040825 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040825: AB_10960426" "unprognostic (6.18e-2)" "unprognostic (1.33e-1)" "unprognostic (3.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.99e-1)" "prognostic favourable (2.08e-4)" "unprognostic (9.97e-3)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "prognostic favourable (6.85e-4)" "unprognostic (1.29e-2)" "prognostic favourable (5.77e-5)" "unprognostic (8.75e-2)" "unprognostic (1.67e-1)" "unprognostic (9.24e-2)" "unprognostic (1.64e-2)" 14.2 17.5 23.5 12.9 26.9 12.1 15.8 38.6 40.4 17.7 16.1 20.7 16.1 13.6 21.4 14.5 19.6 20.0 14.7 13.7 23.8 23.5 16.3 15.9 16.9 16.3 17.9 18.3 30.2 21.9 30.3 16.7 18.3 21.2 14.3 13.2 18.6 18.3 21.1 9.0 18.2 12.7 19.5 16.9 16.9 13.7 27.3 14.8 22.3 17.1 8.4 14.4 16.3 15.6 6.8 4.1 24.0 4.8 6.9 9.7 6.0 12.3 15.0 17.6 20.6 18.4 14.2 14.2 16.5 17.4 27.1 23.8 19.4 12.9 10.8 10.7 18.2 9.2 24.8 14.9 15.4 21.6 19.7 24.4 23.0 13.1 20.3 14.9 17.1 16.5 18.6 29.2 17.7 22.6 15.9 12.7 13.3 11.0 18.1 15.6 18.9 25.0 11.5 12.5 21.6 17.5 18.9 9.5 19.0 21.0 13.7 18.9 11.0 22.0 20.2 15.2 15.3 20.8 19.1 15.5 20.8 11.5 13.9 17.3 15.5 2.5 4.8 8.2 8.7 3.9 8.8 4.6 8.0 9.6 4.1 6.8 9.7 9.5 24.0 6.9 4.8 2.9 8.2 6.0 23.5 26.9 38.6 40.4 23.8 23.5 17.9 18.3 21.2 14.8 IP6K2 IHPK2 ENSG00000068745 "Inositol hexakisphosphate kinase 2" Q9UHH9 3 48688003-48740353 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007532, HPA070811" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA007532: AB_1851542, HPA070811: " "prognostic favourable (1.25e-4)" "unprognostic (2.55e-2)" "unprognostic (8.86e-2)" "unprognostic (6.69e-3)" "unprognostic (1.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.76e-3)" "prognostic favourable (2.95e-4)" "unprognostic (6.57e-3)" "unprognostic (1.56e-1)" "unprognostic (1.92e-3)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (3.50e-2)" "prognostic favourable (1.83e-4)" 18.3 31.1 40.4 20.0 55.9 51.7 28.2 74.1 37.3 29.5 32.5 23.7 34.0 36.9 34.6 56.1 30.0 28.1 24.0 19.0 30.7 19.2 32.4 24.3 18.4 22.5 35.4 27.6 33.9 28.1 23.5 42.3 20.7 29.4 34.9 41.9 22.2 28.3 32.1 19.1 50.0 31.6 21.1 28.3 25.5 27.6 26.0 37.4 31.7 35.7 21.6 19.5 24.1 34.0 27.3 22.8 50.7 25.7 27.9 35.1 19.0 8.7 17.2 35.7 25.1 20.1 25.2 25.8 16.8 18.9 19.3 22.4 14.2 23.6 15.6 13.8 15.6 23.0 17.8 25.1 18.0 18.3 15.7 17.8 53.2 30.4 16.3 16.8 17.4 23.9 36.6 26.1 21.6 26.6 13.3 19.6 22.3 19.5 36.0 23.1 27.4 31.9 15.1 11.8 17.0 26.2 42.2 22.3 33.7 36.3 24.7 17.8 23.9 28.5 18.9 21.0 20.9 13.1 16.5 18.1 21.4 21.9 19.1 19.7 18.3 50.7 22.5 38.5 29.7 21.6 26.5 27.3 25.8 27.7 21.7 25.7 24.2 24.9 35.3 27.9 25.7 22.8 35.1 19.0 40.4 55.9 74.1 37.3 30.7 19.2 35.4 27.6 29.4 37.4 IP6K3 "IHPK3, INSP6K3" ENSG00000161896 "Inositol hexakisphosphate kinase 3" Q96PC2 6 33721670-33746905 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 22.5;skeletal muscle: 87.9" "Cell line enhanced" "Detected in some" "HHSteC: 15.8;HSkMC: 5.7;LHCN-M2: 25.1;RH-30: 11.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 13.0;cerebral cortex: 6.2;midbrain: 22.5;pons and medulla: 7.7;thalamus: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA053644 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA053644: " "unprognostic (3.23e-2)" "unprognostic (2.87e-1)" "unprognostic (2.07e-5)" "unprognostic (1.07e-3)" "unprognostic (2.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.45e-1)" "unprognostic (2.47e-2)" "unprognostic (1.24e-2)" "unprognostic (2.94e-3)" "prognostic unfavourable (6.09e-4)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (2.66e-3)" "unprognostic (1.33e-1)" 2.2 1.0 2.1 0.8 13.0 0.5 0.9 0.6 6.2 1.2 2.2 11.8 1.4 0.8 1.6 1.4 5.2 1.3 0.6 10.0 3.2 1.3 4.7 7.7 2.0 0.6 22.5 1.1 0.6 0.7 0.5 0.5 3.8 7.7 2.8 1.0 1.2 1.4 1.8 87.9 0.5 1.1 1.8 9.2 1.4 0.9 0.6 15.2 0.0 9.9 8.1 0.5 1.5 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.5 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 5.7 0.8 0.1 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.1 0.0 0.0 11.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.1 13.0 0.6 6.2 3.2 1.3 22.5 1.1 7.7 15.2 IPMK ENSG00000151151 "Inositol polyphosphate multikinase" Q8NFU5 10 58191517-58267934 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 6.4" "Group enriched" "Detected in many" 4 "granulocytes: 6.4;monocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037837, HPA057542" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA037837: AB_10670166, HPA057542: " "unprognostic (4.52e-2)" "unprognostic (3.29e-2)" "unprognostic (4.22e-3)" "unprognostic (6.85e-2)" "unprognostic (2.41e-2)" "unprognostic (1.99e-1)" "unprognostic (1.39e-3)" "unprognostic (2.10e-1)" "unprognostic (9.39e-2)" "unprognostic (2.23e-1)" "unprognostic (1.55e-1)" "unprognostic (8.56e-2)" "prognostic unfavourable (9.96e-7)" "unprognostic (1.79e-1)" "unprognostic (4.33e-1)" "unprognostic (1.27e-3)" "unprognostic (9.02e-3)" 12.2 4.1 5.4 6.8 5.6 2.8 6.7 8.7 5.6 5.9 19.4 3.5 2.1 9.5 3.2 5.6 10.8 3.8 8.6 7.4 5.2 5.5 5.3 21.3 11.0 13.8 4.9 3.3 4.8 6.0 22.5 6.1 13.8 4.3 4.4 7.5 4.8 6.4 4.4 9.8 9.0 28.1 4.9 6.0 14.1 4.4 2.9 3.8 11.7 5.9 4.9 5.9 10.4 12.3 0.7 1.0 6.4 2.1 0.4 0.9 0.4 14.6 3.7 5.6 5.4 5.4 6.4 4.8 3.9 8.3 3.3 6.7 7.5 9.4 11.7 7.9 4.6 4.5 4.7 5.1 10.7 5.3 3.5 2.9 3.8 7.2 3.3 4.5 6.7 7.0 4.7 5.6 11.4 7.1 1.9 6.0 5.8 3.6 6.2 8.8 3.5 3.6 0.4 12.0 5.4 6.2 3.8 3.9 6.7 5.0 13.4 3.9 11.2 5.5 6.1 3.6 7.0 7.6 4.9 13.0 7.6 9.3 6.9 4.8 1.4 2.3 1.5 3.3 0.4 1.6 0.4 0.7 0.4 0.2 1.0 0.4 0.9 0.3 6.4 0.4 2.1 0.4 0.1 0.4 5.4 5.6 8.7 5.6 5.2 5.5 4.9 3.3 4.3 3.8 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613184-92670265 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavourable (1.28e-4)" 5.0 7.5 7.6 5.2 12.3 8.3 7.5 13.4 14.1 7.9 4.7 9.7 6.8 3.7 6.0 5.9 29.7 6.4 5.3 8.1 7.9 5.9 5.2 5.8 4.9 6.0 7.1 5.7 6.5 4.2 11.3 11.0 7.1 10.0 5.1 5.3 6.0 10.8 4.3 6.9 31.5 4.6 6.3 6.4 5.8 4.8 12.0 7.7 5.7 5.5 17.8 16.1 4.9 13.7 4.2 3.9 5.8 3.2 1.4 7.5 3.1 11.7 6.3 5.8 5.0 7.2 5.4 19.3 8.4 5.2 8.6 5.0 3.9 4.7 7.3 4.2 11.7 16.9 10.2 11.7 7.2 9.1 6.6 6.0 13.4 6.0 5.1 10.1 7.1 5.3 11.6 10.3 8.1 6.4 8.1 8.9 8.5 16.0 5.8 4.7 9.9 9.4 5.1 6.3 2.9 5.1 7.2 12.2 7.2 6.8 28.2 4.9 6.7 2.5 12.4 6.4 7.3 17.9 8.8 8.2 9.6 4.1 8.4 4.6 6.2 0.0 2.3 5.8 6.4 3.1 7.3 4.1 5.6 5.7 3.6 4.2 4.4 4.8 3.6 1.4 3.2 3.9 7.5 3.1 7.6 12.3 13.4 14.1 7.9 5.9 7.1 5.7 10.0 7.7 IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010500-154019980 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB004461: AB_2249106, HPA054476: " "unprognostic (4.46e-3)" "unprognostic (9.32e-2)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (7.09e-3)" "unprognostic (4.43e-3)" "prognostic unfavourable (3.03e-4)" "unprognostic (7.89e-3)" "unprognostic (3.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "prognostic unfavourable (2.06e-4)" "unprognostic (2.76e-3)" "unprognostic (2.36e-1)" "unprognostic (2.21e-3)" "unprognostic (3.04e-1)" 22.3 23.7 12.1 25.0 11.4 48.3 38.5 7.7 14.8 11.1 24.8 10.8 13.4 29.9 13.2 12.4 25.5 12.2 23.1 14.1 9.9 12.3 23.7 46.9 18.5 37.5 12.6 7.9 15.1 34.6 8.1 15.2 14.3 11.9 18.0 11.0 10.1 31.9 15.9 32.6 15.9 34.6 11.5 12.7 34.0 19.3 14.3 9.8 17.0 12.6 20.4 26.7 17.2 15.3 10.0 13.0 6.7 10.6 6.3 6.7 3.4 76.3 29.7 4.2 34.3 8.4 6.7 18.3 11.4 10.8 17.6 16.4 23.5 34.0 32.6 64.3 12.2 20.9 9.7 18.6 6.9 25.6 29.0 11.9 26.7 14.0 19.4 28.1 20.5 9.3 16.4 16.8 18.6 10.5 20.9 37.8 12.3 28.1 11.5 25.1 10.4 59.3 30.0 21.3 54.8 11.7 14.5 23.6 17.0 13.6 15.2 22.5 5.9 29.9 14.3 21.4 33.9 48.9 70.7 47.6 30.4 59.8 31.3 33.8 22.2 1.3 8.7 6.7 6.7 10.6 5.9 7.5 5.3 5.3 5.4 10.0 3.1 6.1 5.9 6.3 8.1 13.0 2.5 3.4 12.1 11.4 7.7 14.8 9.9 12.3 12.6 7.9 11.9 9.8 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66188879-66254622 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.0" "Cell line enhanced" "Detected in some" "ASC diff: 14.7;ASC TERT1: 12.2;HEL: 12.6;HL-60: 16.7;NB-4: 13.3;THP-1: 20.2;U-937: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 5.6;classical monocyte: 13.1;intermediate monocyte: 13.2;myeloid DC: 6.2;neutrophil: 7.2;non-classical monocyte: 20.6" "Group enriched" "Detected in many" 12 "dendritic cells: 6.2;granulocytes: 7.2;monocytes: 20.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavourable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 21.8 3.7 2.1 10.6 3.6 58.0 13.4 1.0 2.4 8.7 6.5 2.3 5.5 1.7 6.2 8.6 4.9 7.0 7.6 16.0 2.9 2.1 3.6 2.9 22.1 25.6 4.6 0.3 5.9 2.7 1.3 17.9 6.1 3.7 7.0 3.0 5.5 6.0 5.5 5.5 3.3 4.9 6.4 5.9 25.3 6.2 5.1 2.8 1.0 4.9 4.5 5.4 9.5 11.4 0.4 6.2 7.2 20.6 0.9 0.3 3.6 0.0 0.0 0.2 0.0 14.7 12.2 0.0 1.6 0.0 0.9 1.3 0.0 1.2 0.0 0.8 3.0 0.0 1.8 0.0 0.7 0.0 0.0 12.6 0.7 0.0 7.7 16.7 2.3 7.7 0.0 0.7 0.0 4.3 0.0 0.0 0.5 0.0 0.0 13.3 0.7 0.0 0.0 3.6 0.0 0.1 1.8 0.1 0.0 6.5 0.0 0.7 0.0 20.2 4.6 0.0 0.0 0.0 0.0 0.5 0.1 1.2 0.0 14.7 0.0 5.6 13.1 2.2 0.0 13.2 0.0 0.0 0.0 0.0 6.2 0.4 0.0 0.0 7.2 0.9 20.6 0.0 0.3 3.6 2.1 3.6 1.0 2.4 2.9 2.1 4.6 0.3 3.7 2.8 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favourable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favourable (4.42e-5)" 18.0 9.4 5.1 15.0 10.4 10.3 11.3 3.7 6.0 10.3 12.2 9.1 12.5 10.2 13.0 14.1 15.0 9.4 10.8 7.6 6.7 5.2 13.3 11.8 12.0 24.0 13.2 3.9 9.3 20.1 9.1 16.1 14.0 9.8 10.5 10.0 11.9 11.9 15.1 4.1 15.2 15.0 11.8 13.0 25.0 12.3 7.1 11.7 30.3 17.0 7.7 18.9 11.1 10.7 5.1 5.8 16.9 6.0 8.8 7.7 4.7 5.3 3.9 2.8 3.7 10.1 17.0 4.0 7.5 5.3 6.0 5.5 3.3 5.1 9.1 7.4 6.2 4.4 3.1 4.8 8.6 13.0 2.9 8.7 3.0 2.1 5.8 12.0 10.7 9.0 7.8 7.6 4.4 8.8 8.0 6.8 16.4 2.9 10.4 6.8 1.0 4.6 6.9 3.4 4.8 4.6 5.1 2.0 1.9 3.6 4.7 3.6 5.9 10.7 7.8 7.4 1.4 9.0 5.1 8.4 10.8 7.9 7.6 32.4 4.0 16.9 4.6 9.4 7.4 5.4 7.7 4.0 6.1 6.3 4.5 5.1 5.5 5.9 9.3 8.8 6.0 5.8 7.5 4.7 5.1 10.4 3.7 6.0 6.7 5.2 13.2 3.9 9.8 11.7 IRF2BP1 "DKFZP434M154, IRF-2BP1" ENSG00000170604 "Interferon regulatory factor 2 binding protein 1" Q8IU81 19 45883607-45886170 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042164, HPA049480" Approved Supported Nucleoplasm Nucleoplasm "HPA042164: , HPA049480: " "unprognostic (5.90e-2)" "unprognostic (1.34e-1)" "unprognostic (8.86e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-1)" "unprognostic (1.01e-1)" "prognostic favourable (2.32e-4)" "unprognostic (2.60e-1)" "prognostic favourable (3.85e-5)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (2.66e-1)" "unprognostic (5.07e-3)" 14.2 11.9 12.2 9.0 14.1 6.7 8.7 23.1 26.2 12.7 11.2 12.6 10.6 14.4 15.3 8.1 8.2 12.4 12.6 10.8 11.8 11.7 12.0 14.8 10.0 9.5 13.2 12.8 20.3 18.5 12.4 15.6 8.6 12.5 13.5 4.8 12.6 19.6 15.2 33.4 13.4 12.4 9.3 8.7 15.6 16.4 8.0 12.8 17.4 13.7 8.0 8.6 12.0 8.7 2.7 2.0 1.4 1.7 2.4 3.6 1.6 8.2 12.6 3.1 6.9 2.7 1.7 5.1 6.1 3.5 4.9 4.3 4.7 3.9 6.7 4.6 3.1 7.8 2.2 2.3 1.4 8.4 21.9 6.7 3.6 5.9 5.4 6.9 6.3 2.3 3.1 2.5 1.8 3.0 10.5 5.3 1.8 6.4 14.0 37.8 5.8 11.3 16.1 3.6 5.7 3.4 4.6 9.3 16.0 6.4 8.5 7.7 7.0 12.9 4.3 4.2 8.6 3.2 8.6 14.6 16.1 3.9 5.7 6.6 6.1 0.0 1.2 0.4 2.8 1.7 2.8 2.7 2.5 2.3 1.1 2.3 3.6 2.2 1.4 2.4 0.7 2.0 2.3 1.6 12.2 14.1 23.1 26.2 11.8 11.7 13.2 12.8 12.5 12.8 ISPD "hCG_1745121, IspD, Nip" ENSG00000214960 "Isoprenoid synthase domain containing" A4D126 7 16087527-16421322 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 8.3;HEL: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 17 "basophil: 10.7" "Lineage enriched" "Detected in single" 22 "granulocytes: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043810, HPA053554" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA043810: AB_10964489, HPA053554: " "unprognostic (4.65e-3)" "unprognostic (5.92e-2)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (3.39e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-1)" "prognostic favourable (1.38e-11)" "unprognostic (4.01e-2)" "unprognostic (1.78e-4)" "unprognostic (6.26e-2)" "unprognostic (2.79e-1)" 3.0 3.8 4.2 1.9 4.5 2.6 3.0 7.7 7.7 3.7 2.9 3.9 3.4 1.8 4.7 2.4 2.0 2.8 3.2 7.1 4.4 4.5 7.0 10.0 2.9 1.5 4.7 3.9 2.7 3.9 3.6 5.7 8.0 4.6 3.5 3.0 5.7 5.5 10.1 4.5 2.6 1.8 3.7 4.9 1.4 10.2 3.9 2.4 1.1 2.6 2.4 1.4 3.2 3.7 0.3 0.4 10.7 0.1 0.4 0.3 0.0 0.3 2.3 1.2 1.8 1.0 1.5 8.3 1.8 1.2 1.6 1.3 2.6 2.2 0.0 4.0 2.6 3.0 1.4 0.0 2.9 1.0 1.4 11.5 1.4 0.6 1.3 0.9 1.4 2.7 1.2 1.3 0.2 1.2 2.7 0.2 4.1 0.5 1.1 1.0 2.2 0.3 0.0 1.8 0.1 2.7 0.8 2.0 1.3 1.3 2.4 2.5 1.7 2.6 1.3 2.3 2.1 0.3 2.2 0.2 0.0 0.0 1.9 2.7 2.8 10.7 0.1 0.4 0.3 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.3 0.2 0.6 0.4 0.0 0.4 0.0 0.0 4.2 4.5 7.7 7.7 4.4 4.5 4.7 3.9 4.6 2.4 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511393 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: " "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 20.7 16.7 18.9 15.4 26.9 20.5 17.5 19.8 26.7 23.9 18.2 37.9 15.2 16.9 18.4 15.1 35.9 14.5 14.5 17.9 20.4 15.9 21.1 46.5 18.5 16.8 29.2 16.5 19.3 17.1 21.6 26.3 26.9 29.0 17.5 20.4 16.7 20.1 18.4 24.0 19.2 20.3 19.8 30.4 17.3 17.3 34.8 32.3 22.3 22.7 13.0 23.6 19.6 21.0 7.3 11.4 19.6 6.2 6.2 11.4 2.7 20.0 13.2 13.5 9.7 14.9 21.3 16.2 16.3 18.7 20.4 20.0 37.2 30.9 9.8 15.8 20.8 25.4 20.5 32.9 24.9 7.4 6.6 28.4 11.2 22.2 15.6 11.6 12.9 10.8 16.8 17.2 27.0 15.3 16.1 17.0 15.9 10.0 17.0 6.2 6.5 15.7 14.3 28.5 22.6 12.1 34.8 8.3 6.1 30.5 11.9 18.3 14.3 10.5 14.8 24.4 14.7 15.9 12.0 13.5 14.1 14.3 15.1 7.5 14.3 3.6 5.8 6.1 10.8 6.2 11.4 7.3 3.8 5.7 4.5 6.9 3.3 4.9 19.6 6.2 3.8 11.4 4.8 2.7 18.9 26.9 19.8 26.7 20.4 15.9 29.2 16.5 29.0 32.3 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255191 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 28.0;lymphoid tissue: 60.5" "Cell line enriched" "Detected in some" 5 "MOLT-4: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 28 "gdT-cell: 13.8;MAIT T-cell: 9.1;memory CD4 T-cell: 19.5;memory CD8 T-cell: 18.9;naive CD4 T-cell: 28.0;naive CD8 T-cell: 22.8;NK-cell: 9.2;T-reg: 23.1" "Group enriched" "Detected in many" 29 "NK-cells: 9.2;T-cells: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 2.3 0.7 0.5 12.2 0.6 2.5 1.3 1.9 0.5 1.4 3.3 0.0 0.0 0.5 1.2 1.1 1.8 1.4 4.3 0.9 0.5 0.5 1.4 1.2 6.6 60.5 0.9 0.0 0.7 0.7 0.0 0.9 0.1 0.3 1.1 1.3 1.5 3.5 1.1 0.5 1.0 8.9 0.4 1.2 10.7 2.3 1.4 0.0 60.3 1.6 2.7 24.3 4.1 1.3 0.0 0.0 0.4 0.6 9.2 28.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 3.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 9.1 0.0 19.5 18.9 0.0 0.0 28.0 22.8 0.4 9.2 0.6 0.0 23.1 13.6 0.5 0.6 1.9 0.5 0.5 0.5 0.9 0.0 0.3 0.0 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.2" "Group enriched" "Detected in all" 5 "granulocytes: 24.2;monocytes: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria Mitochondria "HPA055230: " "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favourable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 32.0 10.2 44.3 11.9 49.5 12.2 14.4 19.3 50.5 23.8 20.0 29.7 9.6 34.9 20.2 10.2 18.7 15.9 16.1 18.4 49.0 30.6 11.4 13.4 13.0 7.6 42.1 27.1 11.4 15.0 13.2 5.3 11.2 18.5 15.1 13.6 14.5 8.3 19.1 9.4 5.5 36.6 19.4 44.8 14.1 11.9 9.4 26.1 3.4 10.0 3.2 5.5 16.7 16.2 1.9 3.9 24.2 13.0 1.3 1.9 2.4 10.2 21.3 4.0 10.0 8.9 5.0 10.6 4.4 6.6 8.8 5.4 12.2 18.5 6.5 22.0 6.9 12.2 11.4 18.9 2.8 24.1 4.9 14.4 5.7 10.5 6.6 6.5 16.0 3.2 11.4 4.5 10.2 8.6 7.8 7.5 4.2 27.5 5.6 9.3 8.3 9.6 10.6 5.8 9.7 5.9 17.3 10.8 13.6 11.1 22.5 18.8 30.2 8.0 6.7 6.2 6.7 10.3 6.9 7.4 6.7 4.2 5.6 5.1 42.1 2.5 5.2 9.5 1.9 8.6 1.1 1.9 1.2 1.2 3.9 0.7 0.7 1.3 24.2 1.3 13.0 1.9 1.7 2.4 44.3 49.5 19.3 50.5 49.0 30.6 42.1 27.1 18.5 26.1 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.8;intestine: 19.8;stomach 1: 10.7" "Cell line enhanced" "Detected in many" "Hep G2: 22.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 12.3;basal ganglia: 21.2;cerebral cortex: 28.8;hippocampal formation: 10.4;olfactory region: 8.2" "Cell type enriched" "Detected in single" 8 "MAIT T-cell: 4.7" "Lineage enriched" "Detected in single" 13 "T-cells: 4.7" "Group enriched" "Detected in many" 13 "amygdala: 120.1;basal ganglia: 97.6;cerebellum: 62.9;cerebral cortex: 164.4;hippocampal formation: 162.9" "Group enriched" "Detected in many" 7 "amygdala: 12.1;basal ganglia: 40.8;cerebral cortex: 32.2;hippocampal formation: 28.6" HPA040454 Enhanced Approved Approved Vesicles Vesicles "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.4 3.0 12.3 1.1 21.2 0.8 0.4 3.0 28.8 0.6 8.5 0.3 0.0 19.8 0.6 0.5 0.4 0.6 0.6 0.7 10.4 0.9 0.4 0.8 0.4 0.4 1.6 8.2 0.6 2.5 1.7 0.0 0.7 0.3 0.8 3.4 0.0 2.1 0.8 1.4 0.4 19.7 0.7 0.2 0.4 10.7 3.5 0.6 0.0 0.4 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.3 4.7 0.0 4.8 1.3 0.2 5.6 0.0 1.8 10.2 3.0 2.4 2.0 2.1 11.2 0.2 0.0 2.5 0.2 0.5 2.4 0.2 0.1 4.5 3.0 6.8 3.0 22.7 9.2 2.3 0.3 0.1 0.1 1.9 0.6 0.1 8.6 1.3 0.7 3.2 0.2 4.4 0.6 4.0 1.1 1.0 0.4 0.2 0.3 0.5 1.1 2.2 0.0 0.2 0.6 3.4 0.2 4.9 5.1 5.5 8.1 0.7 7.1 0.0 9.1 9.0 1.6 0.0 0.0 0.0 0.3 0.0 4.7 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.3 21.2 3.0 28.8 10.4 0.9 1.6 8.2 0.3 0.6 ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm Nucleoplasm "HPA030273: AB_10601127, HPA072923: " "unprognostic (4.54e-2)" "unprognostic (3.85e-2)" "unprognostic (8.41e-3)" "unprognostic (9.37e-3)" "unprognostic (1.53e-1)" "prognostic favourable (1.72e-5)" "unprognostic (1.24e-1)" "prognostic favourable (6.65e-4)" "unprognostic (2.29e-1)" "unprognostic (9.57e-2)" "unprognostic (1.41e-2)" "unprognostic (1.75e-2)" "unprognostic (3.23e-3)" "unprognostic (2.90e-2)" "unprognostic (7.46e-2)" "unprognostic (6.54e-3)" "unprognostic (7.87e-2)" 23.8 4.2 34.7 13.0 35.1 14.8 15.2 11.1 33.6 14.3 19.7 32.4 8.5 6.0 27.1 15.6 12.6 15.3 8.9 7.8 27.9 24.8 9.7 3.2 13.4 22.7 50.4 16.3 8.8 4.8 10.1 4.2 13.5 40.0 13.1 6.3 20.8 24.9 21.3 9.8 10.5 12.5 32.6 63.1 19.0 12.4 3.2 34.0 20.0 5.9 4.3 17.1 19.6 8.5 3.1 0.9 7.7 3.5 3.0 7.9 2.6 2.8 3.0 4.9 5.6 3.8 2.5 1.3 0.7 3.3 1.5 3.6 0.5 3.5 12.8 4.6 0.7 4.1 6.2 2.5 0.7 1.7 4.2 5.7 3.3 0.0 1.5 5.3 10.2 2.8 3.6 1.7 1.6 10.5 0.0 1.8 0.2 2.6 9.7 7.1 10.6 4.9 3.8 8.8 2.8 11.3 4.5 2.9 3.7 2.3 1.7 28.1 7.2 6.0 7.3 2.0 1.5 1.8 4.5 0.1 4.6 15.7 0.5 4.8 7.4 1.2 1.4 7.7 4.4 2.1 3.9 1.9 5.3 4.5 0.9 3.1 7.9 5.7 5.4 3.0 3.5 0.8 3.0 2.6 34.7 35.1 11.1 27.9 27.9 24.8 50.4 16.3 40.0 34.0 ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717103-40740860 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA050760: , HPA053003: " "unprognostic (4.27e-2)" "unprognostic (3.73e-2)" "unprognostic (8.31e-2)" "unprognostic (9.12e-3)" "unprognostic (1.10e-2)" "unprognostic (9.81e-2)" "unprognostic (6.06e-2)" "prognostic unfavourable (4.91e-4)" "unprognostic (1.48e-1)" "unprognostic (1.54e-3)" "unprognostic (1.84e-3)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.45e-2)" "unprognostic (3.32e-1)" 26.0 8.2 6.6 9.8 10.9 2.4 13.4 4.4 7.7 14.2 9.3 3.7 7.6 8.5 8.8 5.2 46.8 11.0 17.1 10.8 13.2 3.7 7.3 7.7 18.4 6.9 4.4 2.7 6.8 16.4 6.4 9.9 10.8 23.8 12.1 5.2 6.0 15.4 8.4 8.1 21.6 9.8 11.9 17.8 6.5 11.4 3.8 5.2 3.2 7.8 31.4 28.0 10.6 17.1 3.3 2.3 3.9 3.2 0.9 3.5 1.7 6.5 6.2 3.8 6.0 17.5 15.2 6.2 3.9 8.3 4.1 3.6 8.9 6.8 1.8 4.5 5.0 6.9 3.8 16.9 1.7 3.4 3.9 1.4 2.2 6.2 17.3 1.5 1.9 21.1 24.7 3.8 14.2 9.9 5.3 3.2 3.9 8.0 2.2 2.3 1.9 2.8 2.4 1.9 2.5 6.3 11.1 2.7 3.4 3.9 16.1 3.6 7.4 3.9 6.3 2.6 3.9 1.7 2.6 1.8 0.4 1.9 4.1 1.5 2.8 3.9 3.2 1.7 3.5 1.6 1.4 1.4 2.7 1.9 1.5 3.3 1.9 2.2 1.6 0.9 2.2 2.3 2.6 1.7 6.6 10.9 4.4 7.7 13.2 3.7 4.4 2.7 23.8 5.2 JADE2 "JADE-2, KIAA0239, PHF15" ENSG00000043143 "Jade family PHD finger 2" Q9NQC1 5 134524312-134583230 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025959, HPA055789" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA025959: AB_1855289, HPA055789: " "unprognostic (8.98e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (7.69e-2)" "unprognostic (5.56e-2)" "unprognostic (8.25e-2)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.58e-2)" "unprognostic (3.49e-2)" "prognostic favourable (5.36e-6)" "unprognostic (3.73e-1)" "unprognostic (1.76e-3)" "unprognostic (2.68e-1)" "unprognostic (2.87e-2)" 15.6 19.8 16.7 16.1 22.0 9.7 13.9 22.8 21.7 16.0 13.4 15.3 9.2 12.7 13.9 8.4 11.8 20.6 13.2 13.4 17.8 14.5 14.8 4.7 15.0 25.8 30.8 16.0 28.4 14.0 30.9 14.4 8.5 20.1 12.8 8.2 16.4 15.0 16.9 12.0 11.5 17.8 13.0 16.8 22.9 12.9 8.1 30.8 13.0 20.6 6.0 19.2 20.0 22.7 7.3 2.0 6.8 3.0 3.1 6.2 2.4 28.1 20.1 0.6 0.8 7.0 8.5 9.2 5.1 13.4 9.4 11.1 15.2 21.9 31.0 11.4 6.6 6.0 3.6 26.9 4.7 18.7 1.4 7.3 14.0 4.1 7.0 8.0 1.1 5.7 13.1 11.4 14.4 7.1 4.5 11.7 5.7 10.1 13.7 7.2 6.6 10.5 12.3 0.6 12.1 8.8 7.8 4.3 2.8 12.6 0.4 18.0 5.5 9.9 9.9 6.6 6.0 18.7 12.7 5.4 22.5 28.7 10.3 14.3 9.3 6.8 1.2 4.4 6.2 1.1 6.0 7.3 5.7 5.6 2.0 5.5 5.6 5.6 1.3 3.1 3.0 1.2 5.8 2.4 16.7 22.0 22.8 21.7 17.8 14.5 30.8 16.0 20.1 30.8 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-64966504 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved "CAB013088: " "prognostic favourable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favourable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favourable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 46.7 20.4 15.5 31.1 16.5 21.2 56.6 24.3 20.4 27.3 27.1 16.3 16.5 13.8 28.2 22.0 27.0 20.7 27.7 27.3 15.3 16.5 31.4 38.3 36.5 61.4 15.6 14.1 33.3 29.1 28.3 39.8 22.9 25.1 26.0 22.2 18.1 19.8 21.3 45.1 29.7 29.3 30.7 16.3 52.7 20.9 17.3 15.0 62.7 29.0 17.9 42.5 37.2 29.3 20.2 15.4 34.9 17.1 68.1 27.5 25.8 10.9 14.4 6.0 0.6 69.4 39.3 7.8 17.2 25.4 14.3 16.9 4.7 6.1 16.7 13.4 30.5 6.2 4.0 13.3 20.4 22.1 6.4 22.7 7.5 10.2 25.6 8.7 15.8 34.5 18.5 21.6 22.6 44.6 8.2 17.9 15.8 6.3 4.7 5.8 4.1 8.6 6.8 17.3 6.1 36.9 19.4 4.2 12.7 23.6 11.1 10.1 23.5 5.4 40.4 17.2 7.7 38.9 9.1 11.2 5.1 13.3 16.0 11.5 7.7 31.2 10.9 31.5 22.8 15.2 27.5 20.2 22.0 25.7 15.4 16.1 24.3 20.7 34.9 68.1 17.1 10.5 26.5 25.8 15.5 16.5 24.3 20.4 15.3 16.5 15.6 14.1 25.1 15.0 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "ASC diff: 18.9;HDLM-2: 26.7;HEL: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: , HPA043870: " "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.4 1.4 2.5 18.9 4.9 0.4 3.4 2.9 2.6 1.7 0.1 0.8 0.1 0.8 2.0 0.8 1.5 2.1 1.9 26.7 0.5 54.8 2.9 0.7 3.9 3.7 2.8 4.0 0.9 1.1 1.8 2.4 3.9 6.4 4.7 0.9 0.9 5.2 1.3 1.7 1.9 2.7 0.7 2.0 1.3 1.6 0.9 1.0 1.5 1.0 0.7 6.5 5.0 4.0 1.3 4.1 2.4 1.2 2.2 0.5 5.2 1.8 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 68.3" "Cell line enhanced" "Detected in some" "HDLM-2: 20.1;HEL: 9.0;HMC-1: 9.2;Karpas-707: 23.5;U-266/70: 9.1;U-266/84: 13.5;U-937: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA070314: " "unprognostic (5.59e-3)" "prognostic favourable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.8 1.7 4.0 24.5 8.5 12.0 2.7 2.4 3.1 1.9 2.3 1.0 0.0 2.2 1.7 2.0 2.5 3.5 3.6 4.3 2.7 2.8 3.8 2.0 8.4 68.3 7.5 0.0 11.0 2.0 0.4 2.3 4.1 5.3 3.0 2.4 1.6 6.1 1.5 0.7 1.3 9.5 2.5 8.4 36.1 3.2 1.8 5.8 20.9 3.4 1.7 28.8 5.3 2.4 7.4 4.5 16.9 9.6 8.4 15.0 6.8 0.1 0.3 0.3 1.0 0.4 1.4 0.2 0.5 0.0 0.0 0.1 0.0 0.9 0.4 1.9 0.4 0.1 0.0 0.2 0.0 20.1 0.0 9.0 0.0 0.8 0.7 0.0 9.2 5.0 0.2 0.0 0.0 0.2 0.0 23.5 0.0 0.4 3.6 0.0 0.1 0.7 4.6 0.0 0.4 0.5 0.0 0.0 0.3 0.1 0.2 0.0 2.0 1.3 0.4 0.0 0.4 0.0 0.0 9.1 13.5 2.5 0.1 13.7 0.2 1.2 4.9 0.2 12.6 9.6 14.5 6.5 15.0 13.1 4.5 7.4 14.9 13.0 16.9 8.4 8.8 3.7 11.8 6.8 4.0 8.5 2.4 3.1 2.7 2.8 7.5 0.0 5.3 5.8 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell line enhanced" "Detected in many" "CACO-2: 32.1;HEL: 19.6;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.6 1.4 0.8 1.4 0.6 32.1 2.5 0.1 0.4 3.6 0.2 0.8 0.0 1.1 0.0 0.3 19.6 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.6 4.5 0.1 0.4 2.3 0.0 0.0 2.0 3.1 1.0 1.6 0.0 0.1 0.3 1.2 9.2 0.4 0.3 0.3 0.7 0.1 8.1 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113108-42121358 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain "HPA048958: " "unprognostic (1.71e-1)" "unprognostic (9.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (9.07e-2)" "unprognostic (1.91e-3)" "unprognostic (3.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "prognostic favourable (3.57e-4)" "unprognostic (2.78e-2)" "prognostic unfavourable (1.41e-8)" "unprognostic (3.97e-2)" "unprognostic (2.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.29e-3)" 16.9 15.9 30.2 13.6 28.6 8.6 14.0 24.0 42.0 11.2 11.9 10.9 13.1 14.9 13.9 8.9 11.4 14.2 11.8 7.6 27.8 11.5 10.0 11.8 7.2 11.2 27.6 18.0 23.5 16.5 14.8 11.9 10.7 26.0 12.9 9.6 6.0 17.3 14.5 20.1 19.9 13.4 9.7 13.9 15.6 13.0 7.8 29.7 5.3 11.7 6.4 10.4 11.2 21.7 2.0 1.6 0.1 0.4 0.6 2.7 0.8 11.0 21.4 3.2 11.8 4.5 3.7 14.0 7.2 3.9 16.1 8.0 14.4 9.1 21.8 18.3 5.5 16.6 13.0 11.5 5.7 12.1 26.9 5.4 13.2 13.0 4.7 14.4 14.5 4.3 9.8 9.0 5.7 6.4 13.6 4.2 4.2 11.9 34.4 10.6 6.8 0.0 8.2 6.3 14.4 4.3 11.2 15.3 6.7 7.7 17.0 5.9 12.6 6.9 4.9 8.2 8.3 11.8 12.8 11.2 10.7 12.1 5.9 12.5 4.5 0.0 0.4 0.0 0.8 0.0 1.7 2.0 1.9 2.4 1.6 1.6 2.7 0.7 0.1 0.6 0.1 0.4 0.3 0.8 30.2 28.6 24.0 42.0 27.8 11.5 27.6 18.0 26.0 29.7 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040023-20154404 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526" Supported Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB004526: AB_2128417, HPA002470: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 10.6 6.6 30.1 9.4 27.5 24.9 6.8 22.0 20.1 10.2 9.4 27.6 7.9 10.9 7.8 5.4 17.3 7.7 8.0 21.9 24.7 18.0 10.8 24.0 10.1 12.7 26.8 15.9 18.2 11.6 38.1 8.7 8.5 24.2 9.5 8.1 10.7 20.9 9.2 33.4 8.9 13.0 8.7 21.4 11.7 9.0 1.8 31.1 8.7 10.0 7.4 12.0 8.7 11.0 2.1 2.7 5.5 1.5 1.1 4.8 0.8 1.5 3.9 2.2 3.6 9.0 8.4 5.1 5.0 7.4 5.3 7.8 1.1 2.6 13.4 2.1 9.4 1.1 5.4 1.6 4.5 12.2 5.1 11.8 6.2 0.4 4.2 1.8 15.3 3.6 2.9 4.6 3.0 5.0 7.5 19.0 7.5 1.8 3.8 3.5 0.9 3.9 5.1 4.1 2.8 7.2 8.0 1.1 2.4 2.8 4.5 17.0 4.7 8.0 4.8 9.0 3.6 3.3 5.7 7.3 15.1 3.2 8.2 7.8 18.9 1.3 1.1 2.8 3.6 1.5 3.4 1.0 3.1 2.5 0.9 2.1 1.1 2.1 5.5 1.1 1.1 2.7 4.8 0.8 30.1 27.5 22.0 20.1 24.7 18.0 26.8 15.9 24.2 31.1 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016953 Approved Supported Nucleoplasm Nucleoplasm "HPA016953: AB_1851277" "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favourable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 18.5 19.5 21.2 16.0 27.4 34.3 21.6 29.4 37.1 22.1 24.1 28.2 22.3 16.5 30.1 24.8 21.2 32.9 24.5 21.1 18.3 19.2 22.6 16.1 20.8 18.3 19.0 25.7 29.5 23.2 38.8 22.0 32.7 24.6 21.2 19.4 29.3 23.6 27.5 24.6 27.6 19.2 25.2 20.1 22.0 21.9 30.7 22.8 26.9 26.5 19.1 22.1 24.4 22.0 25.0 24.0 40.4 23.6 24.8 28.6 23.3 19.1 23.4 21.3 16.2 16.9 17.9 22.4 13.9 22.7 23.3 20.3 17.0 22.9 17.6 19.9 24.3 16.2 26.5 23.3 14.1 22.9 17.0 25.8 19.3 20.1 24.3 28.1 31.0 19.0 26.1 15.3 31.4 14.6 26.6 27.6 22.0 34.8 23.8 32.9 18.6 15.1 19.6 14.1 32.2 21.3 29.1 19.9 20.9 13.2 25.0 26.5 24.5 18.2 18.7 18.9 16.7 14.9 14.9 21.2 21.8 25.9 16.3 13.8 15.4 23.4 23.6 40.4 25.7 22.3 22.1 21.1 22.5 25.5 24.0 25.0 28.6 23.3 26.1 24.8 23.3 14.5 21.5 23.3 21.2 27.4 29.4 37.1 18.3 19.2 19.0 25.7 24.6 22.8 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051990 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Approved "Nucleoli,Nuclear speckles,Cytosol" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: , HPA065052: " "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 20.8 10.9 15.3 19.8 20.3 36.8 22.6 29.9 18.7 19.7 14.6 19.4 14.4 10.7 20.6 12.1 16.9 16.5 14.3 13.0 15.5 11.5 12.3 13.6 26.9 28.2 23.2 10.3 27.2 13.1 26.8 22.3 20.9 15.7 14.1 12.0 12.8 15.1 17.0 21.0 25.5 18.0 25.0 22.9 20.4 14.0 14.1 21.7 30.4 17.9 14.3 20.1 16.9 24.2 4.7 1.8 10.9 1.6 3.1 3.9 1.4 12.9 10.6 17.5 11.1 9.8 11.2 5.9 8.7 11.3 10.8 8.4 6.7 6.2 19.2 8.7 8.5 8.3 13.6 8.2 12.7 9.9 7.9 27.6 6.6 5.0 7.4 14.5 12.7 9.3 9.4 10.0 12.4 10.3 23.1 12.2 9.8 5.7 29.5 4.6 6.7 4.2 23.6 19.6 6.1 5.3 14.9 10.9 9.4 10.1 6.8 7.0 15.6 6.4 12.0 13.3 9.4 11.8 9.3 10.0 16.1 20.8 7.1 6.6 11.5 3.5 1.6 2.8 3.5 1.2 3.9 2.4 2.6 3.3 1.0 4.7 3.6 2.9 10.9 3.1 1.2 1.8 3.5 1.4 15.3 20.3 29.9 18.7 15.5 11.5 23.2 10.3 15.7 21.7 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74825582-75032622 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favourable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 11.6 9.5 11.1 13.2 11.9 15.1 12.4 19.0 11.6 16.7 12.2 13.3 15.3 7.2 25.1 13.0 12.0 13.2 12.0 10.0 10.6 9.5 9.0 7.3 9.2 9.0 9.0 9.9 24.6 13.3 24.8 31.1 9.4 8.9 13.5 9.6 10.1 17.9 12.0 15.3 10.6 11.3 16.2 9.3 10.4 13.0 12.8 12.1 26.6 13.0 8.9 12.5 14.3 12.7 3.2 1.9 1.6 1.1 5.3 3.7 1.5 3.9 4.1 7.4 6.2 5.8 8.6 3.6 3.5 6.9 3.0 3.3 2.7 4.6 8.4 1.9 6.4 3.1 3.9 3.0 4.9 3.5 5.7 3.1 3.3 3.8 4.4 7.3 2.1 5.6 5.0 4.1 6.6 3.4 3.3 7.3 3.8 4.2 7.0 3.4 4.1 22.7 11.0 3.8 1.8 2.2 2.0 3.7 6.1 3.6 6.5 3.2 3.7 2.9 4.2 4.2 5.0 2.8 3.3 5.4 6.2 5.6 4.6 7.8 0.9 0.7 1.1 1.6 3.2 0.9 3.4 2.4 2.4 2.7 1.2 3.2 3.7 3.4 0.9 5.3 0.8 1.9 2.4 1.5 11.1 11.9 19.0 11.6 10.6 9.5 9.0 9.9 8.9 12.1 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788555-49835030 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 15.8 14.3 16.9 16.2 25.9 44.4 17.5 37.0 35.0 19.5 17.3 23.8 17.9 13.1 27.3 18.6 18.8 19.5 14.6 25.3 16.8 21.8 18.7 11.3 13.9 15.3 17.0 23.6 21.9 13.6 44.4 19.8 19.8 21.9 20.4 14.9 20.8 18.9 23.3 31.7 22.7 14.7 21.8 17.9 15.8 15.5 63.7 19.1 25.9 28.6 14.5 20.6 22.7 17.4 13.0 12.7 15.2 11.4 20.6 20.7 14.2 13.0 18.4 17.8 12.5 8.4 11.2 21.6 11.4 13.3 20.5 14.7 28.4 9.3 15.0 18.5 12.1 11.5 17.0 11.9 24.2 16.3 16.8 17.8 13.4 11.8 12.6 18.2 14.8 10.6 11.9 18.4 23.0 15.1 19.7 14.9 19.1 19.9 25.8 13.1 44.3 16.1 16.3 28.5 12.9 9.6 14.8 19.4 16.5 11.6 7.0 10.7 25.6 16.1 9.0 26.0 14.1 11.3 14.7 21.9 23.9 17.6 11.8 10.9 16.2 15.2 11.0 15.1 16.9 8.9 20.7 13.0 16.3 17.1 12.7 12.2 20.6 16.2 13.1 20.6 11.4 6.6 14.3 14.2 16.9 25.9 37.0 35.0 16.8 21.8 17.0 23.6 21.9 19.1 KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31115754-31131393 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 17.8;neutrophil: 17.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm Nucleoplasm "HPA066324: " "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favourable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" 18.4 21.7 22.7 29.4 23.6 26.6 29.7 48.9 30.8 28.0 24.8 18.3 27.5 15.7 29.8 48.3 16.7 35.0 28.2 32.7 23.0 21.2 20.8 18.9 26.3 29.0 20.2 21.0 52.8 31.4 38.0 22.2 31.5 16.8 21.2 17.7 22.1 35.1 26.2 39.8 22.1 19.7 25.9 20.5 27.4 18.6 27.3 18.4 30.2 31.7 22.6 22.2 20.2 26.6 2.1 4.1 17.8 4.6 1.7 2.9 1.9 7.6 11.8 14.8 4.4 17.6 13.2 15.2 6.8 13.1 11.0 12.1 5.9 16.7 18.1 10.8 8.5 9.1 23.6 11.5 10.9 15.1 16.0 7.8 8.7 18.7 15.8 12.9 14.2 12.4 23.1 8.2 23.8 10.5 20.8 14.9 5.6 22.3 19.9 24.4 16.7 7.2 32.1 12.1 21.2 8.9 4.6 15.6 15.8 4.1 11.5 5.8 12.5 21.5 6.2 4.7 9.9 5.2 4.9 14.2 14.3 10.2 7.1 17.3 7.0 3.9 4.4 17.8 1.9 2.4 2.4 2.1 2.2 2.6 4.1 1.8 2.9 2.1 17.4 1.7 4.6 1.4 1.3 1.9 22.7 23.6 48.9 30.8 23.0 21.2 20.2 21.0 16.8 18.4 KCMF1 "DEBT91, DKFZP434L1021, PCMF, ZZZ1" ENSG00000176407 "Potassium channel modulatory factor 1" Q9P0J7 2 84971093-85059472 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030383, HPA030384" Enhanced Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA030383: AB_10599977, HPA030384: AB_10601230" "unprognostic (8.01e-2)" "unprognostic (1.98e-2)" "unprognostic (9.95e-2)" "unprognostic (7.42e-3)" "unprognostic (1.24e-2)" "unprognostic (8.54e-2)" "prognostic unfavourable (2.33e-7)" "unprognostic (5.68e-3)" "unprognostic (1.43e-1)" "unprognostic (9.81e-2)" "prognostic unfavourable (6.10e-5)" "unprognostic (4.98e-2)" "prognostic unfavourable (4.18e-6)" "unprognostic (6.11e-2)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (1.01e-1)" 19.2 13.3 17.9 20.2 16.0 23.6 26.1 13.4 18.6 15.0 20.2 10.7 20.3 15.4 16.3 18.8 28.5 12.8 17.9 30.4 16.5 12.0 14.8 20.7 16.4 18.8 13.7 11.1 17.2 48.6 14.7 18.7 20.5 14.4 17.5 21.4 14.0 19.4 15.7 67.2 17.6 20.6 25.7 10.3 16.7 16.8 29.0 11.5 19.7 18.7 21.8 22.5 23.9 34.0 4.0 4.2 8.1 3.4 2.8 8.8 1.5 27.1 21.4 19.1 14.7 20.2 19.5 32.5 29.1 27.1 28.0 18.7 26.1 29.4 29.6 29.3 39.4 18.1 14.8 28.2 36.9 22.1 10.4 18.9 16.1 26.6 39.5 20.7 18.1 20.1 44.6 27.4 76.0 21.0 18.7 23.6 27.9 25.1 20.0 11.5 20.8 18.0 14.4 26.8 18.5 25.3 23.9 18.4 13.8 16.9 21.6 28.2 10.0 13.2 17.9 28.6 27.9 26.6 30.2 26.9 33.2 30.0 21.5 15.3 21.4 5.0 2.6 8.1 4.5 2.2 3.6 3.5 3.2 3.4 2.2 4.0 2.8 3.1 7.5 2.8 3.4 4.2 8.8 1.5 17.9 16.0 13.4 18.6 16.5 12.0 13.7 11.1 14.4 11.5 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078259-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 31.8;TIME: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004028 Enhanced Supported "Plasma membrane" "Intracellular and membrane" 7400000 "Plasma membrane" "CAB004028: AB_2212507" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavourable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 19.7 6.2 1.8 4.4 3.1 0.4 20.5 1.1 2.2 11.4 6.0 1.8 11.5 2.3 28.8 10.2 5.2 9.5 6.2 12.1 2.3 1.7 7.8 10.4 13.2 14.1 3.1 2.9 6.0 8.1 8.0 6.8 34.5 3.9 9.5 1.4 27.6 7.1 10.3 5.3 3.0 3.8 7.7 2.6 4.4 4.2 5.3 1.2 0.5 20.0 5.3 3.0 4.4 12.0 0.1 0.1 0.7 0.0 0.2 0.2 0.1 0.0 0.0 1.7 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 0.2 31.8 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.8 3.1 1.1 2.2 2.3 1.7 3.1 2.9 3.9 1.2 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100772 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 60.2;kidney: 38.4;liver: 67.0" "Cell line enhanced" "Detected in many" "HEL: 18.5;Hep G2: 26.9" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Cytosol 320000 Cytosol "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavourable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 0.9 1.9 2.1 1.2 2.7 0.7 1.9 5.2 3.9 1.1 22.3 1.9 0.2 40.0 1.5 0.9 1.1 1.6 0.6 0.6 2.2 2.2 38.4 67.0 0.7 0.8 3.5 1.9 1.8 4.2 0.6 0.7 0.4 3.0 0.9 0.6 0.6 1.7 0.7 1.4 1.0 60.2 0.9 1.8 0.8 1.0 1.6 3.6 0.0 0.5 1.2 0.6 0.7 0.9 5.1 7.3 0.6 6.6 5.4 8.8 6.0 13.9 10.6 1.6 6.4 1.2 0.3 1.4 0.9 0.6 1.3 0.8 5.1 3.0 2.1 3.4 0.0 6.2 5.5 1.8 0.4 4.9 10.0 18.5 2.8 26.9 0.6 2.5 2.2 0.1 0.8 1.6 0.1 1.2 3.3 3.5 0.1 9.1 3.0 2.0 2.3 4.2 10.6 0.8 11.8 1.6 1.7 6.0 9.3 2.0 3.6 3.9 1.6 1.1 1.1 0.4 2.1 0.9 3.7 4.4 7.8 3.6 1.8 6.0 1.0 0.0 6.6 0.4 5.4 3.8 7.4 5.1 8.8 7.8 6.1 5.1 6.4 7.8 0.6 5.4 1.6 7.3 5.5 6.0 2.1 2.7 5.2 3.9 2.2 2.2 3.5 1.9 3.0 3.6 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 65.5" "Group enriched" "Detected in some" 13 "HEL: 47.7;HMC-1: 100.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7" "Group enriched" "Detected in many" 6 "granulocytes: 12.7;NK-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" 48000000 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: , CAB072867: , HPA004471: AB_1078431, HPA073252: " "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favourable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 8.1 1.6 9.5 6.6 11.8 3.7 65.5 18.3 12.0 12.1 10.3 6.5 10.2 5.8 8.9 4.2 9.9 2.5 15.5 2.4 36.0 4.4 9.4 1.1 13.8 3.8 3.6 6.0 28.5 2.1 1.3 2.3 6.2 5.7 9.6 10.4 20.7 12.9 6.9 1.3 14.6 8.9 10.2 3.9 3.2 12.8 4.0 4.5 0.4 28.9 4.3 4.9 9.8 12.5 0.0 1.8 12.7 0.9 9.7 1.9 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.6 0.9 2.5 3.2 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 2.1 0.0 1.1 47.7 0.0 0.0 0.0 0.0 100.2 0.0 0.0 0.0 0.0 5.6 0.6 0.1 0.0 0.0 0.2 0.4 1.3 0.0 0.1 0.0 0.0 0.0 4.7 1.2 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 12.7 0.0 10.0 0.1 0.0 1.9 0.0 0.3 0.7 1.8 0.0 0.0 0.0 0.8 9.7 0.9 0.0 0.0 0.1 9.5 11.8 18.3 12.0 36.0 4.4 3.6 6.0 5.7 4.5 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: " "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 14.4 11.3 17.7 17.0 19.2 28.6 16.8 43.8 21.2 17.3 14.6 19.8 18.1 8.5 21.8 17.1 10.6 15.7 14.1 10.2 17.3 13.4 13.1 9.3 15.3 19.6 16.6 18.7 35.6 16.8 28.9 21.8 10.2 15.4 15.6 12.4 14.4 14.2 19.2 11.1 16.8 14.2 15.2 12.1 15.7 12.3 7.9 23.4 16.6 16.6 7.8 19.4 18.8 24.6 6.7 3.5 8.3 2.0 6.5 5.3 0.8 11.9 5.5 14.9 11.2 9.1 10.9 4.4 5.4 7.8 5.7 6.6 11.1 8.7 14.7 11.1 7.9 10.4 15.8 5.9 11.3 16.2 6.1 28.8 5.1 6.0 5.1 17.2 5.6 5.2 6.1 12.4 16.7 8.8 18.7 12.6 7.1 9.3 11.4 10.1 9.0 8.2 8.7 14.3 4.9 8.4 9.0 12.3 8.0 13.5 4.4 2.8 7.6 5.8 13.0 9.8 8.8 7.1 9.6 3.7 2.8 9.9 3.7 12.7 5.8 8.3 2.0 4.6 5.3 1.3 4.3 6.2 4.8 4.6 0.8 6.7 4.9 4.8 1.3 6.5 1.4 3.5 3.9 0.8 17.7 19.2 43.8 21.2 17.3 13.4 16.6 18.7 15.4 23.4 KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35718019-35738878 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006487: AB_1080587" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.41e-2)" "unprognostic (7.95e-2)" "unprognostic (9.92e-2)" "unprognostic (3.53e-3)" "unprognostic (2.33e-2)" "unprognostic (4.57e-2)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (3.13e-3)" "unprognostic (2.63e-3)" "unprognostic (9.47e-3)" "unprognostic (2.10e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" 10.2 9.3 11.4 14.2 13.1 18.4 10.4 23.9 11.4 10.0 12.0 14.2 12.9 13.8 13.0 7.1 11.4 11.6 12.6 7.5 11.0 5.3 9.9 8.9 10.6 14.7 14.7 6.8 15.3 19.6 10.8 13.3 9.3 11.2 12.1 5.6 13.8 14.7 10.0 13.3 19.9 12.3 12.2 12.4 15.8 12.1 21.5 14.9 14.1 14.9 7.0 14.2 12.4 14.2 0.4 0.7 3.2 0.7 2.1 0.7 0.2 11.3 19.2 8.9 9.7 4.6 4.5 9.3 5.5 4.0 5.6 4.3 12.8 5.8 10.1 8.7 4.6 7.5 8.0 4.7 2.5 15.0 8.9 18.2 9.0 6.4 4.5 11.1 20.9 6.1 6.4 5.7 6.3 5.5 15.2 12.7 3.6 11.6 9.4 9.6 8.2 6.8 14.8 5.8 5.5 3.1 10.1 10.1 8.1 8.4 13.6 5.8 8.3 11.8 7.6 11.3 12.2 7.5 11.7 17.5 10.7 8.1 6.1 10.3 7.8 1.0 0.7 0.6 0.7 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.4 3.2 2.1 0.3 0.7 0.2 0.2 11.4 13.1 23.9 11.4 11.0 5.3 14.7 6.8 11.2 14.9 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436005 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm Nucleoplasm "HPA074736: " "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favourable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 13.9 12.6 11.7 16.7 18.6 29.7 14.5 24.8 14.1 18.4 12.6 15.5 21.4 9.7 20.2 20.6 14.4 12.8 12.7 10.8 13.4 9.5 10.3 11.4 13.0 12.1 17.7 9.4 18.8 18.4 18.8 18.9 38.0 12.6 14.0 11.8 12.6 15.8 22.9 30.3 25.2 13.1 13.6 16.0 14.6 14.9 13.6 19.6 22.6 16.9 9.3 16.8 17.8 31.6 5.6 3.5 16.1 3.9 5.5 2.9 0.6 9.5 4.8 9.0 9.5 16.2 9.8 10.5 5.0 3.8 4.0 4.9 9.1 5.8 15.2 7.3 9.1 5.5 9.6 7.3 6.7 9.6 4.9 9.0 7.2 6.3 7.9 15.3 11.1 8.2 10.1 5.7 7.6 5.7 14.5 13.2 8.7 13.3 11.0 13.9 5.4 4.8 7.4 8.1 7.9 6.9 9.9 13.1 10.3 8.2 14.7 5.4 4.8 12.5 7.2 6.7 3.5 7.1 7.1 13.8 6.7 16.4 8.7 12.5 6.8 8.8 3.5 4.3 2.1 2.2 2.9 5.6 1.7 1.7 1.7 3.8 2.7 1.8 16.1 5.5 3.9 3.5 1.3 0.6 11.7 18.6 24.8 14.1 13.4 9.5 17.7 9.4 12.6 19.6 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49059774 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 12.1 7.6 4.9 6.7 10.8 26.1 6.8 11.7 10.5 9.5 6.5 5.8 13.0 5.5 15.7 7.4 8.8 8.9 5.8 9.1 6.1 3.5 6.2 6.5 22.9 9.6 6.7 3.3 9.7 11.6 13.3 9.2 12.9 13.7 6.7 6.6 9.8 7.6 8.0 16.1 13.6 9.4 7.1 9.1 13.6 8.3 7.3 5.7 6.2 11.0 6.1 7.6 7.0 6.3 2.0 2.2 5.9 0.5 1.5 0.8 0.6 17.0 16.2 16.4 13.2 17.0 11.4 17.6 9.0 9.4 11.7 6.3 28.4 7.2 17.7 11.7 12.6 11.6 21.6 10.0 9.8 10.3 17.3 22.5 16.9 15.2 11.7 26.7 22.6 9.7 14.3 16.4 17.0 17.4 28.2 9.8 13.2 18.7 13.2 24.9 15.5 14.0 19.9 10.1 6.4 9.8 18.9 13.7 11.6 13.9 13.7 9.5 13.6 23.4 23.1 9.2 16.5 8.1 15.1 14.0 9.0 17.2 10.6 13.8 6.9 0.6 0.5 3.0 0.8 0.2 0.4 0.3 0.3 0.5 0.3 2.0 0.3 0.8 5.9 1.5 0.1 2.2 0.0 0.6 4.9 10.8 11.7 10.5 6.1 3.5 6.7 3.3 13.7 5.7 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409358 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA064495: " "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 7.6 5.4 8.9 14.0 7.5 20.2 7.9 9.8 14.1 13.9 9.1 9.9 21.4 7.3 15.7 9.5 22.3 12.3 8.3 10.9 8.1 5.5 6.7 7.4 8.7 8.4 7.8 10.6 7.2 13.1 6.8 7.4 9.9 12.8 18.6 9.1 7.9 19.3 12.5 13.6 15.6 9.1 11.0 10.3 13.3 9.0 5.2 8.6 42.2 17.2 8.9 19.7 12.3 14.2 3.5 3.8 7.8 3.8 4.1 5.4 0.6 12.2 7.8 9.3 14.3 6.0 10.7 12.8 18.2 8.8 10.6 9.4 8.9 7.2 28.3 10.6 12.1 11.4 13.3 6.7 11.4 11.9 13.8 23.7 8.2 4.4 9.0 18.4 6.0 4.6 8.4 11.5 10.7 8.7 42.9 13.1 8.7 8.9 18.6 27.5 4.3 8.9 22.2 8.0 7.6 7.4 14.9 12.8 10.1 18.2 9.3 8.4 12.9 23.5 11.0 12.0 8.7 14.2 13.1 7.3 7.6 25.9 8.2 9.7 10.0 4.1 2.5 7.8 2.8 3.8 5.4 3.5 3.3 4.3 2.0 2.3 1.8 2.3 3.4 4.1 3.6 3.8 2.7 0.6 8.9 7.5 9.8 14.1 8.1 5.5 7.8 10.6 12.8 8.6 KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063648 Supported Nucleoplasm Nucleoplasm "HPA063648: " "unprognostic (5.82e-2)" "unprognostic (4.25e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (3.52e-1)" "unprognostic (2.94e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "unprognostic (5.54e-2)" "unprognostic (1.21e-1)" "unprognostic (3.79e-3)" "unprognostic (2.62e-1)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "prognostic favourable (9.30e-4)" 17.6 19.1 20.9 23.4 22.5 23.7 27.3 38.8 26.7 22.4 21.2 19.9 32.3 21.8 26.2 22.7 19.7 20.4 18.2 15.1 23.8 15.3 19.1 21.5 17.4 16.9 18.6 22.2 27.4 24.0 27.4 28.1 26.6 17.0 24.9 21.5 15.4 25.2 30.4 18.8 20.8 24.0 23.4 18.4 19.6 19.7 19.1 23.6 38.0 30.9 17.5 19.1 20.5 22.5 4.5 5.5 16.0 5.2 8.9 5.9 2.7 10.1 7.7 15.8 10.2 3.7 9.3 17.1 7.3 5.1 9.1 5.4 24.2 16.3 8.3 12.8 10.0 5.4 10.9 8.5 13.5 9.3 6.3 7.9 9.1 10.0 13.4 11.0 10.9 9.1 17.6 11.0 11.6 9.0 11.6 9.7 7.8 21.0 7.7 11.6 16.9 5.8 12.9 12.3 22.3 6.8 9.9 13.8 16.5 11.3 11.5 51.5 14.6 7.3 9.5 12.4 16.5 9.5 7.4 12.5 5.4 17.6 7.8 7.0 13.2 7.8 3.7 16.0 4.7 5.2 3.3 3.4 5.1 5.7 3.6 4.5 5.9 5.2 11.3 8.9 4.8 5.5 4.0 2.7 20.9 22.5 38.8 26.7 23.8 15.3 18.6 22.2 17.0 23.6 KMT5C "MGC2705, SUV420H2" ENSG00000133247 "Lysine methyltransferase 5C" Q86Y97 19 55339853-55348120 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 16.4;SCLC-21H: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052294 Uncertain Approved Nucleoplasm Nucleoplasm "HPA052294: " "unprognostic (4.02e-2)" "unprognostic (3.45e-2)" "unprognostic (2.92e-3)" "unprognostic (6.77e-3)" "unprognostic (2.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (8.69e-2)" "unprognostic (3.04e-1)" "unprognostic (9.48e-3)" "unprognostic (1.49e-2)" "prognostic unfavourable (1.05e-8)" "unprognostic (7.39e-2)" "unprognostic (2.96e-1)" "unprognostic (9.41e-2)" "unprognostic (2.39e-2)" 5.0 5.6 8.5 7.3 15.7 13.4 5.4 20.0 10.7 5.1 7.5 11.2 4.9 11.9 7.0 5.4 4.6 11.0 7.4 4.2 11.2 4.5 5.1 4.4 5.5 4.6 17.1 5.3 6.1 8.5 6.2 11.7 6.5 9.6 6.6 3.8 6.3 7.7 6.3 6.6 13.5 8.5 3.6 6.2 6.2 9.8 7.0 14.7 10.1 5.1 2.3 3.5 6.3 4.6 0.3 0.8 0.9 0.6 1.1 0.8 0.3 4.9 3.5 3.3 2.7 0.7 0.9 9.2 1.4 0.6 0.5 1.3 2.2 4.2 4.9 1.8 1.1 2.7 2.1 1.8 0.6 4.4 16.4 3.9 2.5 2.2 1.2 2.3 4.7 0.8 2.4 1.6 0.9 1.1 9.6 2.8 0.6 5.7 6.5 5.1 5.9 5.1 9.7 3.8 4.8 0.8 1.2 16.0 6.8 0.7 3.7 2.0 4.1 2.9 1.2 1.6 4.0 0.5 1.0 8.1 4.0 3.1 0.8 5.5 2.2 0.3 0.6 0.3 0.7 0.4 0.0 0.1 0.5 0.7 0.6 0.3 0.3 0.8 0.9 1.1 0.0 0.8 0.2 0.3 8.5 15.7 20.0 10.7 11.2 4.5 17.1 5.3 9.6 14.7 KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968983 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.4;pituitary gland: 24.6" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 7.2;SCLC-21H: 5.3;TIME: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced "HPA035536: AB_10673485" "unprognostic (1.74e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-2)" "unprognostic (9.11e-2)" "unprognostic (8.42e-2)" "unprognostic (6.91e-3)" "unprognostic (1.10e-2)" "unprognostic (5.78e-2)" "unprognostic (5.80e-2)" "unprognostic (2.05e-4)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (5.02e-2)" "unprognostic (5.68e-2)" "unprognostic (8.14e-3)" "unprognostic (5.74e-2)" 0.9 5.0 13.2 1.1 13.8 1.1 1.7 27.4 17.2 1.0 1.9 1.3 2.2 1.0 0.8 2.6 0.9 1.7 1.0 0.8 12.9 4.8 3.5 0.8 1.2 1.6 2.2 10.8 0.8 3.0 0.9 24.6 0.9 7.7 1.3 2.3 0.2 1.2 3.4 0.9 1.0 1.0 0.9 2.9 1.0 1.7 3.2 3.0 0.0 3.8 0.0 1.5 2.3 0.5 0.1 0.2 0.8 0.1 0.2 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.1 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 1.5 0.1 0.0 0.5 1.2 0.0 0.0 0.1 0.7 1.4 5.3 0.1 0.0 0.0 0.0 1.1 0.0 10.8 0.0 0.8 0.0 0.2 0.9 1.5 0.0 0.4 0.0 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.1 0.2 0.0 0.0 13.2 13.8 27.4 17.2 12.9 4.8 2.2 10.8 7.7 3.0 KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol 21000 Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" "unprognostic (6.51e-2)" "unprognostic (8.67e-3)" "unprognostic (1.05e-2)" "unprognostic (5.98e-3)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-2)" "unprognostic (2.47e-1)" "unprognostic (8.60e-3)" "unprognostic (1.43e-1)" "unprognostic (3.65e-2)" "unprognostic (3.10e-2)" "unprognostic (5.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" 4.4 5.2 12.2 5.1 18.9 3.9 7.0 17.8 17.6 4.7 3.8 14.2 5.5 4.1 5.5 5.4 4.6 8.5 4.8 13.5 12.1 9.3 8.1 12.0 4.1 7.3 18.4 12.1 7.1 5.0 8.9 8.1 4.5 12.2 8.9 2.7 5.8 7.0 8.4 17.0 12.2 4.8 5.8 10.2 5.8 4.0 6.9 17.2 3.7 7.5 2.8 7.4 8.1 8.1 12.1 7.6 3.5 5.1 4.6 9.6 4.9 4.0 9.3 8.5 8.4 7.7 9.7 4.4 5.6 6.4 5.5 8.3 5.1 7.6 7.8 2.8 4.2 13.2 12.6 10.9 7.1 8.7 8.8 5.1 22.5 9.2 6.9 4.9 2.2 4.2 6.9 7.2 6.9 9.7 7.8 6.9 7.2 2.6 11.3 3.3 14.9 7.2 13.5 7.3 14.5 7.6 1.7 9.0 7.7 8.9 2.2 5.1 5.4 1.9 6.4 4.2 7.2 6.2 4.9 12.7 10.7 9.6 8.0 7.6 3.4 0.1 3.1 3.3 7.8 2.2 6.2 12.1 8.1 8.1 7.6 5.8 8.6 9.6 3.5 4.6 5.1 4.8 8.7 4.9 12.2 18.9 17.8 17.6 12.1 9.3 18.4 12.1 12.2 17.2 KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA026538: AB_1852076, HPA027168: AB_1852078" "prognostic favourable (3.19e-5)" "unprognostic (3.36e-3)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" "prognostic favourable (1.86e-4)" "unprognostic (2.61e-1)" "unprognostic (3.61e-3)" "unprognostic (2.11e-1)" "prognostic favourable (2.80e-4)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" "prognostic favourable (5.02e-6)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" 22.2 26.8 16.6 13.2 19.3 10.6 27.5 14.9 23.5 23.7 17.5 20.0 13.0 19.4 24.1 21.2 27.2 18.9 17.8 13.2 18.6 14.2 27.3 23.8 17.1 17.6 16.9 22.2 27.4 28.6 27.0 19.5 21.9 23.4 19.0 19.6 19.5 21.0 20.7 10.4 22.0 17.2 22.1 14.8 20.7 23.5 15.6 17.2 15.5 24.5 13.4 20.2 25.2 17.7 9.6 17.0 9.2 12.7 11.5 16.7 8.2 20.4 4.3 20.9 7.0 7.5 21.0 18.2 12.6 23.7 16.1 21.0 6.2 7.2 13.5 9.6 9.3 5.8 5.9 9.7 24.7 7.9 8.4 12.1 4.1 10.3 24.6 16.9 3.3 17.7 9.8 11.0 20.0 15.6 15.5 7.1 15.1 6.7 18.0 8.2 12.5 3.8 18.4 14.7 7.2 33.9 20.9 15.3 18.6 16.7 22.3 10.9 12.3 4.1 10.4 6.8 4.5 21.6 9.1 9.6 4.8 9.0 3.3 7.5 5.7 5.6 12.7 7.1 9.1 7.9 12.6 9.6 11.8 10.5 17.0 9.3 12.4 10.4 9.2 11.5 10.2 6.3 16.7 8.2 16.6 19.3 14.9 23.5 18.6 14.2 16.9 22.2 23.4 17.2 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718256 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 15.4 12.9 17.6 12.5 17.6 19.4 14.7 38.4 16.9 15.9 13.6 17.4 9.5 10.1 17.7 11.8 12.2 14.6 11.1 11.7 15.1 8.8 11.5 11.1 12.7 12.6 18.2 8.8 23.6 12.2 22.3 21.8 17.2 15.5 16.3 12.5 14.1 13.8 11.9 12.4 12.8 14.7 15.8 13.0 13.5 11.6 10.6 19.6 20.5 12.9 6.5 12.8 14.7 14.7 7.4 4.6 9.5 11.4 4.2 8.9 2.9 6.1 4.8 10.2 14.4 9.6 12.6 7.8 8.1 8.2 8.8 8.8 7.8 5.3 9.9 8.3 11.3 8.6 13.3 8.7 13.9 9.1 10.6 20.0 6.1 7.0 8.9 18.7 14.6 8.4 14.0 9.9 17.0 10.9 24.6 10.2 8.6 7.3 9.7 7.7 6.0 4.7 9.5 12.2 4.6 8.1 8.7 6.8 10.9 11.4 8.3 6.0 8.6 16.2 13.4 7.0 11.0 8.3 13.0 8.5 9.3 11.4 6.4 10.6 10.3 9.5 4.2 6.6 8.9 7.7 8.0 5.8 7.0 7.4 4.6 7.4 6.0 7.8 2.9 4.2 11.4 4.1 6.7 2.9 17.6 17.6 38.4 16.9 15.1 8.8 18.2 8.8 15.5 19.6 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973032-21061547 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA039191: , HPA049037: " "unprognostic (2.77e-1)" "prognostic unfavourable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 22.9 13.0 3.0 8.6 5.7 12.8 33.0 7.9 3.7 16.6 14.0 6.8 9.3 2.9 21.2 12.7 15.1 11.0 20.6 14.1 5.4 2.6 12.4 11.0 19.8 10.9 5.2 2.4 17.4 10.2 5.0 3.5 18.3 6.3 13.7 4.5 16.7 8.0 11.1 23.0 9.3 7.4 34.6 7.5 15.2 10.4 27.8 5.2 1.4 17.2 13.8 7.0 20.3 28.0 0.1 1.5 3.3 1.9 1.3 3.1 0.5 3.3 3.7 8.3 5.0 9.8 12.9 7.6 11.2 11.7 11.8 10.1 10.6 5.1 0.0 5.5 17.1 4.9 4.9 5.1 17.5 1.9 1.2 6.2 4.7 7.9 15.3 1.6 2.2 19.1 9.4 7.7 5.2 16.4 1.1 0.2 14.8 5.8 0.1 5.8 2.0 1.8 1.4 14.8 0.0 8.4 1.6 0.1 0.0 8.8 5.8 11.6 5.0 3.2 20.6 12.5 8.4 9.1 7.1 1.5 0.8 0.0 3.0 1.9 9.5 0.4 1.9 1.8 1.6 1.5 3.1 0.1 0.2 0.5 1.5 0.0 0.1 0.3 3.3 1.3 0.6 0.1 0.0 0.5 3.0 5.7 7.9 3.7 5.4 2.6 5.2 2.4 6.3 5.2 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 64.4;liver: 154.2" "Cell line enhanced" "Detected in many" "BEWO: 35.1;Hep G2: 27.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 64.4" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044767 Approved Nucleoplasm "Secreted to blood" 6470000000 9500000000 Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavourable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favourable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 4.4 3.6 6.3 2.2 3.7 0.9 4.3 64.4 9.6 4.5 4.4 7.3 1.4 1.3 5.3 3.0 1.8 3.5 3.5 4.5 8.4 1.8 3.9 154.2 5.6 1.9 5.5 6.3 4.7 2.5 5.9 2.7 5.5 9.2 6.4 1.3 1.8 2.4 6.2 3.4 9.9 2.4 3.8 7.5 3.9 2.3 2.2 6.1 1.4 7.6 1.6 1.4 2.6 4.5 1.8 0.8 5.0 1.1 1.3 1.4 0.1 2.4 4.0 5.9 6.7 5.2 7.3 35.1 9.8 4.2 6.6 4.7 13.1 3.0 1.3 1.8 14.1 8.7 1.4 13.4 4.1 0.6 3.6 1.7 8.7 27.3 7.1 0.3 4.7 12.6 12.8 13.7 4.8 4.8 3.7 0.5 4.7 4.0 1.6 4.2 3.9 2.2 1.7 6.5 1.4 1.8 4.3 0.2 3.0 14.8 0.7 1.6 8.4 2.6 9.2 8.6 13.4 9.4 3.5 8.1 2.1 3.7 4.1 1.1 7.4 2.4 1.1 5.0 0.9 0.1 1.3 1.2 0.7 0.8 0.2 1.8 1.4 0.4 2.8 1.3 0.5 0.8 0.0 0.1 6.3 3.7 64.4 9.6 8.4 1.8 5.5 6.3 9.2 6.1 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 112.2;lymphoid tissue: 153.0" "Group enriched" "Detected in some" 6 "MOLT-4: 98.9;U-698: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "gdT-cell: 83.4;MAIT T-cell: 77.5;memory CD4 T-cell: 86.1;memory CD8 T-cell: 90.2;naive CD4 T-cell: 97.0;naive CD8 T-cell: 91.3;NK-cell: 42.8;T-reg: 112.2" "Group enriched" "Detected in many" 13 "NK-cells: 42.8;T-cells: 112.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favourable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favourable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favourable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavourable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 2.6 0.7 0.4 28.2 0.5 3.8 1.3 0.3 0.5 1.7 3.9 0.5 0.9 2.2 1.1 4.5 2.3 1.6 3.8 1.0 0.4 0.4 3.0 2.3 6.6 34.9 0.9 0.5 1.2 0.8 0.0 0.8 0.7 0.6 2.2 1.9 1.3 8.4 1.3 0.9 1.0 16.5 0.7 1.0 28.9 3.5 0.7 0.5 153.0 2.9 1.5 27.1 5.8 2.1 6.1 0.5 2.5 0.3 42.8 112.2 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 12.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 57.0 0.0 0.0 0.0 0.6 0.3 0.4 83.4 0.3 77.5 4.0 86.1 90.2 0.3 6.1 97.0 91.3 2.5 42.8 0.3 0.5 112.2 109.3 0.4 0.5 0.3 0.5 0.4 0.4 0.9 0.5 0.6 0.5 LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: " "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavourable (9.67e-4)" "prognostic unfavourable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" 7.7 9.7 7.0 13.7 8.7 12.3 7.1 10.2 10.1 11.6 10.7 5.2 12.6 15.7 18.7 15.0 13.0 9.9 12.6 21.7 7.5 9.2 15.2 13.8 10.0 12.5 6.1 6.0 15.4 16.7 10.8 21.8 5.7 7.0 10.7 10.6 9.7 9.5 16.3 10.9 9.4 25.0 11.3 5.5 8.0 8.4 12.1 4.2 20.7 17.9 11.9 11.7 9.1 10.4 9.6 2.8 10.5 3.9 4.1 12.6 2.8 10.9 14.6 7.9 13.3 1.8 4.2 11.2 8.0 7.9 8.5 7.2 14.6 13.0 7.1 7.4 12.3 12.5 26.0 10.7 8.4 8.9 8.9 13.0 9.1 14.1 8.4 18.4 10.0 3.2 8.5 9.0 12.5 5.9 11.9 6.8 6.5 8.5 10.5 10.9 8.6 8.4 10.3 15.8 14.5 6.7 16.2 9.2 14.2 17.8 11.9 10.3 8.6 6.3 6.7 15.5 12.8 8.2 12.5 4.9 10.2 16.0 15.8 13.5 11.8 10.5 2.5 4.8 5.6 3.9 6.6 7.5 8.7 7.1 2.8 9.6 12.6 12.1 7.4 4.1 3.5 2.2 4.0 2.8 7.0 8.7 10.2 10.1 7.5 9.2 6.1 6.0 7.0 4.2 LCMT1 "CGI-68, PPMT1" ENSG00000205629 "Leucine carboxyl methyltransferase 1" Q9UIC8 16 25111729-25178231 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041559, HPA043530" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA041559: , HPA043530: " "unprognostic (9.08e-2)" "prognostic favourable (2.78e-4)" "unprognostic (1.18e-1)" "unprognostic (3.71e-1)" "unprognostic (3.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavourable (5.85e-4)" "unprognostic (1.41e-2)" "unprognostic (7.41e-2)" "unprognostic (4.45e-2)" "unprognostic (4.62e-2)" "unprognostic (1.16e-1)" "prognostic favourable (7.53e-6)" "unprognostic (1.23e-1)" "unprognostic (8.99e-2)" "unprognostic (1.84e-3)" "unprognostic (6.71e-2)" 9.8 18.0 27.9 11.6 30.6 13.9 18.1 27.5 36.4 15.4 17.1 15.5 17.5 13.1 16.2 26.7 13.4 16.8 14.1 25.3 22.8 27.5 17.8 7.5 10.8 11.9 21.7 26.7 23.8 31.4 25.3 20.5 18.9 24.8 15.7 17.2 15.0 14.4 18.3 31.6 16.5 12.7 15.1 18.9 10.1 12.6 29.8 14.4 16.9 15.5 14.3 15.3 11.7 12.1 19.7 17.6 21.6 18.9 15.8 38.9 19.5 16.8 15.9 14.9 20.5 13.4 19.6 15.3 10.6 17.5 15.5 20.4 20.1 15.5 10.3 15.2 16.0 8.7 15.4 14.5 21.0 10.5 23.4 5.5 16.2 32.5 30.5 13.3 9.2 22.1 16.1 17.6 18.4 14.1 8.8 13.6 17.0 43.1 15.8 25.5 22.7 16.5 18.8 13.6 20.0 17.5 11.9 24.3 15.1 12.6 19.6 24.1 19.9 6.1 8.3 15.4 10.8 10.0 10.4 17.7 17.9 10.9 18.9 11.6 11.3 12.7 18.9 21.6 20.6 16.7 22.6 19.7 25.6 22.3 17.6 14.3 23.1 21.1 7.4 15.8 17.5 9.1 38.9 19.5 27.9 30.6 27.5 36.4 22.8 27.5 21.7 26.7 24.8 14.4 LCMT2 "KIAA0547, MGC9534, PPM2, TYW4" ENSG00000168806 "Leucine carboxyl methyltransferase 2" O60294 15 43323649-43330605 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039401, HPA048176" Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA039401: AB_10805478, HPA048176: " "unprognostic (4.32e-2)" "unprognostic (1.44e-1)" "unprognostic (1.55e-1)" "unprognostic (4.11e-2)" "unprognostic (1.99e-1)" "unprognostic (2.27e-1)" "unprognostic (9.08e-2)" "unprognostic (5.14e-2)" "unprognostic (3.52e-2)" "unprognostic (2.20e-1)" "unprognostic (3.33e-3)" "unprognostic (9.57e-2)" "prognostic favourable (5.69e-9)" "unprognostic (2.28e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.57e-1)" 7.9 10.9 6.5 8.3 8.1 2.5 25.9 11.4 10.1 10.8 7.4 7.2 10.6 5.2 10.3 12.7 11.0 10.2 6.7 8.4 6.7 8.4 11.9 9.2 6.2 9.9 6.1 7.6 13.0 8.2 13.7 10.1 6.4 9.6 10.2 7.5 8.9 10.3 13.8 7.9 6.2 8.4 8.6 4.8 9.6 8.7 7.1 9.6 12.2 9.8 11.2 13.9 7.4 9.6 6.3 6.9 5.5 4.0 3.3 10.5 5.0 6.0 4.8 11.3 9.8 12.1 3.7 5.5 7.4 8.9 9.7 10.7 7.1 2.8 5.1 15.2 8.4 14.3 0.0 9.8 7.4 7.9 5.2 9.2 12.9 4.1 7.4 0.0 6.9 5.8 9.5 7.2 6.6 3.1 11.6 6.9 11.6 9.4 10.3 4.3 4.9 4.0 12.2 10.0 5.0 16.9 6.9 15.2 12.9 9.8 8.3 4.2 10.1 14.1 2.6 11.4 5.2 13.0 12.0 4.7 11.0 2.1 7.1 7.6 11.8 2.4 4.0 5.5 4.0 3.8 5.5 5.0 6.7 4.8 6.9 6.3 10.5 6.8 1.3 3.3 3.5 3.9 5.3 5.0 6.5 8.1 11.4 10.1 6.7 8.4 6.1 7.6 9.6 9.6 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 55.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.9;RH-30: 23.5;U-2 OS: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved "Intracellular and membrane" 620000 "HPA069130: " "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favourable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 10.4 4.9 8.3 12.6 13.5 6.5 15.7 8.3 12.0 10.9 17.3 11.2 0.8 11.9 15.0 5.9 7.9 4.1 16.9 10.1 7.1 11.8 6.6 1.9 15.6 18.1 15.0 6.6 3.0 55.0 1.7 2.6 6.2 19.4 13.0 9.6 8.4 16.5 7.3 3.7 43.0 11.6 6.0 10.2 13.2 28.4 3.4 5.2 5.8 4.4 10.4 19.8 9.0 8.3 2.6 2.5 12.8 7.7 1.3 4.5 1.5 0.7 7.0 9.3 1.3 1.0 0.9 0.6 2.7 1.4 2.4 3.0 3.0 18.9 0.5 8.5 7.3 13.5 1.4 2.5 1.2 4.1 0.3 2.1 3.7 1.5 0.0 3.0 3.9 1.7 6.4 3.9 0.4 0.9 0.3 0.1 1.8 16.8 0.0 4.2 11.3 5.2 0.8 23.5 1.4 0.9 2.2 8.6 2.1 3.1 0.7 0.1 5.1 3.6 2.2 5.4 26.0 0.2 7.4 0.1 0.0 0.7 6.0 8.1 1.0 5.3 5.9 12.8 2.0 7.7 2.4 1.3 2.0 1.0 2.5 2.6 2.2 2.0 3.2 1.3 7.0 0.6 4.5 1.5 8.3 13.5 8.3 12.0 7.1 11.8 15.0 6.6 19.4 5.2 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39458587-39485109 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria,Cytosol Mitochondria "Nucleoplasm, Cytosol" "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favourable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 9.8 12.9 9.9 7.0 12.7 10.2 11.3 10.2 13.3 7.0 10.7 12.9 8.1 10.4 9.1 10.7 11.6 11.9 7.4 14.0 10.6 10.6 15.7 15.5 5.7 9.0 12.3 10.5 19.2 12.4 10.0 11.5 6.8 15.7 8.2 12.4 9.0 7.8 7.0 42.7 8.8 9.9 13.6 12.4 8.9 9.9 20.1 13.2 8.7 8.8 13.5 8.3 10.0 7.9 9.6 5.8 3.7 7.1 6.9 16.7 4.3 3.9 3.0 4.0 3.7 8.3 8.1 3.4 4.6 2.5 4.3 2.9 5.0 5.5 14.4 5.3 1.7 3.5 11.1 6.3 5.7 1.6 2.8 6.0 1.6 5.0 7.6 13.1 3.9 7.8 10.4 5.0 16.0 4.9 14.3 3.6 5.2 2.5 7.3 16.8 5.2 10.0 6.4 10.7 8.7 5.1 2.1 4.3 3.7 2.6 3.5 14.8 3.9 6.0 1.8 3.4 7.6 4.5 10.6 7.0 10.6 10.1 5.3 15.3 2.9 2.0 6.2 3.7 6.1 7.1 12.6 9.6 8.3 8.0 5.8 8.5 16.7 11.5 3.3 6.9 5.1 5.4 5.2 4.3 9.9 12.7 10.2 13.3 10.6 10.6 12.3 10.5 15.7 13.2 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.2" "Cell line enhanced" "Detected in all" "U-87 MG: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028064, HPA028516" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles, Cytosol" "HPA028064: AB_10600111, HPA028516: AB_10601751" "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavourable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavourable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavourable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 8.8 8.6 31.6 18.2 18.6 6.3 7.4 14.3 44.1 11.5 6.6 7.1 6.6 6.9 7.3 5.3 6.4 6.0 10.8 6.3 26.8 32.9 5.2 2.6 12.5 22.0 33.4 22.2 12.1 8.1 4.0 7.2 8.0 45.2 6.1 4.7 4.8 18.1 9.6 10.9 6.8 7.2 7.6 10.8 18.4 7.8 10.4 6.5 4.3 7.5 3.7 18.1 14.1 7.2 4.6 8.6 3.8 7.7 6.9 2.4 3.1 17.2 13.5 10.3 17.1 13.6 18.5 7.5 10.7 10.3 8.7 9.7 7.8 17.0 10.7 4.8 13.1 10.4 3.8 6.6 3.3 18.5 6.7 7.9 4.6 8.9 15.6 6.0 29.0 18.2 5.9 7.0 3.7 12.9 5.3 3.4 10.8 15.1 5.1 10.8 19.5 8.4 7.5 16.0 6.7 9.6 3.7 4.1 9.4 6.9 16.5 8.6 5.2 5.4 15.3 13.9 12.9 35.7 17.1 3.9 4.3 19.5 51.4 4.4 9.4 0.1 6.5 3.8 2.4 7.7 1.8 4.6 0.6 1.5 8.6 2.4 0.2 0.7 0.7 6.9 4.7 0.8 0.4 3.1 31.6 18.6 14.3 44.1 26.8 32.9 33.4 22.2 45.2 6.5 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 37.8;hTCEpi: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 14.7;neutrophil: 37.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB019313: , HPA008183: AB_1079252, HPA053882: " "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 9.4 6.6 23.5 23.6 26.2 29.4 17.0 9.9 16.8 11.0 20.9 15.6 10.7 13.1 12.9 8.7 33.7 22.1 28.7 6.0 15.4 10.7 15.4 19.9 21.6 18.1 20.8 7.2 11.4 19.9 20.0 12.8 64.3 23.3 17.1 22.1 10.1 25.7 16.2 9.7 36.7 13.3 10.1 28.3 17.4 18.5 16.8 17.9 12.4 25.8 15.6 15.3 13.1 20.0 1.0 1.6 37.2 1.9 2.4 5.6 1.6 7.0 1.1 4.9 2.7 2.1 2.5 37.8 4.7 2.2 4.7 4.0 6.1 3.3 6.9 8.4 7.0 14.4 5.7 24.6 3.0 5.0 6.2 5.0 5.6 6.5 3.2 9.2 9.2 4.0 70.1 3.8 11.5 12.0 2.8 5.0 6.4 5.5 5.6 3.2 4.6 1.8 7.5 8.3 3.8 5.5 16.8 6.3 5.7 3.5 22.7 9.4 18.9 3.7 7.2 4.2 6.6 2.3 4.3 2.8 4.1 6.0 2.7 4.4 1.8 2.1 1.9 14.7 1.3 1.3 2.4 0.8 2.3 1.7 0.7 1.0 2.3 1.8 37.2 2.4 0.5 1.6 5.6 1.6 23.5 26.2 9.9 16.8 15.4 10.7 20.8 7.2 23.3 17.9 LIPT2 ENSG00000175536 "Lipoyl(octanoyl) transferase 2" A6NK58 11 74491712-74493733 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040249 Approved Approved Vesicles,Centrosome Vesicles Centrosome "HPA040249: AB_10795275" "unprognostic (8.80e-2)" "unprognostic (9.67e-2)" "unprognostic (5.12e-3)" "unprognostic (1.09e-1)" "unprognostic (6.74e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-2)" "unprognostic (8.96e-2)" "unprognostic (1.11e-2)" "prognostic favourable (1.63e-4)" "unprognostic (6.11e-2)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (9.45e-2)" "unprognostic (1.01e-1)" "unprognostic (1.51e-2)" "unprognostic (1.35e-1)" 2.0 4.1 2.6 2.6 3.0 2.1 5.8 2.3 4.3 3.1 4.0 3.4 6.5 5.8 3.4 6.5 3.6 5.8 8.8 2.9 3.3 2.6 8.1 5.3 4.0 8.4 3.5 1.0 6.2 10.8 6.2 4.3 8.3 2.9 4.6 3.6 3.8 5.9 6.9 11.3 2.4 6.3 3.1 2.9 4.2 5.6 19.0 0.8 8.7 6.4 5.5 4.3 4.6 3.8 11.2 7.2 6.6 4.9 8.1 14.8 5.4 2.5 3.2 7.0 3.3 2.9 0.6 9.9 0.9 1.6 4.4 2.8 10.5 3.5 15.5 6.0 0.6 3.7 3.2 2.4 1.7 3.6 3.2 4.5 2.8 2.8 3.3 5.2 6.2 1.6 2.6 2.2 2.9 0.3 3.5 4.4 1.3 4.0 6.9 7.9 6.2 4.2 5.6 7.7 4.3 2.9 8.7 7.1 4.5 6.5 2.0 9.4 6.3 3.9 1.2 1.0 2.6 1.5 2.3 7.3 6.5 10.5 0.8 3.0 3.4 0.0 4.9 6.6 5.9 3.0 8.8 11.2 7.9 7.2 5.3 11.0 14.8 11.2 1.1 8.1 3.7 7.2 3.7 5.4 2.6 3.0 2.3 4.3 3.3 2.6 3.5 1.0 2.9 0.8 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106885-98209633 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: " "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavourable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favourable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 5.1 10.3 13.7 5.6 21.3 17.3 5.6 16.6 34.3 7.3 13.8 6.1 5.6 12.6 6.1 6.3 12.7 6.4 7.9 16.9 11.0 10.1 10.1 8.5 10.0 5.1 7.5 18.9 8.0 21.0 22.2 10.0 4.8 13.2 7.9 11.8 5.4 10.5 6.5 17.5 11.5 13.8 5.7 5.5 6.8 9.4 8.0 6.9 7.2 8.7 5.7 7.4 8.3 8.1 0.6 0.7 4.8 0.9 0.3 1.6 0.5 9.9 11.7 9.1 9.3 4.9 3.9 8.5 4.1 4.5 4.1 4.9 9.2 9.1 5.2 11.9 5.3 10.9 10.5 6.3 6.4 7.4 7.4 3.5 10.5 9.2 6.0 6.3 6.4 2.7 8.8 8.4 11.4 6.1 9.2 11.1 3.7 13.5 6.6 3.8 11.1 5.7 7.3 6.2 10.3 6.8 17.5 6.5 13.1 8.3 15.2 6.0 4.2 2.6 7.4 8.5 14.0 16.9 9.4 4.9 8.6 10.5 5.7 5.0 10.1 1.2 0.6 0.5 0.8 0.3 0.5 0.6 0.9 0.9 0.3 0.6 1.1 1.6 4.8 0.3 0.9 0.7 0.8 0.5 13.7 21.3 16.6 34.3 11.0 10.1 7.5 18.9 13.2 6.9 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513189 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.1" "Cell line enhanced" "Detected in many" "HMC-1: 8.4;SK-BR-3: 10.0;U-266/70: 9.3;U-266/84: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: " "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favourable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 1.3 4.4 19.8 2.3 28.6 2.0 2.0 20.0 38.1 2.0 1.5 6.0 0.2 6.2 1.4 1.5 2.3 1.6 1.9 1.7 17.2 11.1 2.5 1.3 3.2 2.2 6.5 23.8 1.3 2.1 8.5 6.1 2.1 12.5 3.5 1.2 1.6 5.2 3.1 1.2 2.4 4.0 1.2 6.6 1.8 2.9 1.5 10.3 0.0 2.3 0.0 2.2 1.6 1.2 0.0 0.0 0.0 0.2 0.0 0.4 0.1 4.5 3.0 0.3 0.0 0.0 0.0 4.4 0.0 0.2 0.0 0.1 2.2 3.6 1.6 1.2 0.0 2.1 0.3 1.6 0.0 0.0 1.2 0.2 0.3 0.7 0.0 0.0 8.4 0.2 0.9 0.0 0.0 0.1 1.4 2.8 0.0 3.0 0.6 0.8 1.1 0.9 3.8 0.0 1.3 1.1 0.7 0.7 2.8 0.1 10.0 0.0 3.8 0.2 0.1 0.0 0.8 0.1 0.0 9.3 7.5 0.4 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 19.8 28.6 20.0 38.1 17.2 11.1 6.5 23.8 12.5 10.3 LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" "Cell Junctions" Cytosol "HPA002235: AB_1079261, HPA071091: " "unprognostic (4.95e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "prognostic favourable (3.08e-7)" "unprognostic (2.67e-1)" "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" 16.9 2.5 11.8 1.7 24.6 0.8 13.2 4.4 33.3 5.9 7.2 1.5 11.2 8.3 4.5 3.2 21.7 5.6 4.8 6.9 6.1 5.5 10.0 3.7 2.5 1.8 3.8 11.6 2.1 12.9 10.8 5.0 21.6 4.8 5.1 5.6 2.0 22.1 10.0 5.1 10.0 8.2 2.8 1.3 0.9 8.0 4.1 2.0 0.7 15.0 5.7 7.8 5.8 7.7 1.4 1.1 1.5 1.9 3.8 1.6 0.6 1.6 0.6 1.9 1.0 3.5 7.3 9.2 1.5 0.7 0.0 0.0 2.7 8.4 2.1 1.2 4.2 1.6 0.0 0.3 0.0 0.5 4.6 2.9 1.7 1.6 1.4 2.7 0.8 5.4 0.3 0.5 0.0 2.8 1.7 1.0 6.6 4.7 2.4 1.8 4.8 1.0 1.5 0.7 0.9 6.3 8.8 2.3 2.6 0.7 9.7 1.0 5.2 1.4 8.0 10.5 3.1 3.4 1.8 3.9 0.6 1.4 9.6 2.4 1.9 1.5 0.5 0.3 1.0 0.5 1.5 1.4 1.5 1.5 0.8 0.9 1.6 1.2 0.4 3.8 1.9 1.1 1.3 0.6 11.8 24.6 4.4 33.3 6.1 5.5 3.8 11.6 4.8 2.0 LPCAT1 "AGPAT10, AGPAT9, AYTL2, FLJ12443" ENSG00000153395 "Lysophosphatidylcholine acyltransferase 1" Q8NF37 5 1456480-1523977 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 35.6" "Cell line enhanced" "Detected in many" "BEWO: 34.2;EFO-21: 32.9;PC-3: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012501, HPA022268" Enhanced Supported "Endoplasmic reticulum,Lipid droplets" "Endoplasmic reticulum" "Lipid droplets" "HPA012501: AB_1845224, HPA022268: AB_1845225" "unprognostic (5.33e-3)" "prognostic unfavourable (7.11e-5)" "unprognostic (3.11e-1)" "prognostic unfavourable (3.67e-4)" "unprognostic (3.13e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (1.88e-8)" "unprognostic (5.90e-2)" "unprognostic (6.37e-2)" "unprognostic (2.08e-2)" "prognostic favourable (4.90e-5)" "unprognostic (4.89e-2)" "prognostic unfavourable (2.64e-7)" "unprognostic (2.60e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (4.03e-1)" 9.8 5.6 5.2 9.0 5.7 5.1 7.4 9.2 9.5 5.4 7.5 2.9 4.5 3.9 7.0 3.2 3.2 5.9 5.8 4.3 5.3 5.2 4.9 3.1 35.6 8.5 3.2 3.7 5.0 5.4 3.1 5.6 10.0 4.6 5.2 2.3 13.6 4.5 4.4 3.5 3.2 5.9 5.5 3.3 28.8 9.4 3.0 2.9 5.8 4.7 1.4 8.1 6.6 10.6 0.9 0.7 2.4 1.7 1.7 3.6 0.6 2.0 3.0 0.5 3.2 0.3 0.5 34.2 7.7 0.4 0.4 0.3 1.1 0.9 6.7 32.9 0.2 5.7 0.6 0.2 0.2 16.2 13.9 1.6 4.8 2.0 0.6 1.7 4.6 0.6 0.1 0.3 0.1 0.4 3.6 1.2 0.0 4.2 6.3 2.6 12.0 22.9 12.0 0.5 4.9 1.3 2.7 4.3 4.2 6.1 5.5 1.8 2.6 2.6 3.8 0.6 7.5 2.3 2.7 4.3 4.1 1.5 1.4 2.8 2.0 0.0 0.6 0.8 3.6 1.7 3.6 0.9 0.8 1.8 0.7 0.7 0.1 1.0 2.4 1.7 1.2 0.2 0.8 0.6 5.2 5.7 9.2 8.0 5.3 5.2 3.2 3.7 4.6 2.9 LPCAT2 "AGPAT11, AYTL1, FLJ20481, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55508998-55586670 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 33.5;HaCaT: 25.7;HL-60: 28.7;HMC-1: 47.8;WM-115: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 28.8;eosinophil: 49.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favourable (3.43e-4)" "prognostic favourable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" 10.5 7.5 10.5 8.0 16.2 43.5 9.9 1.7 7.5 11.0 5.2 18.2 36.5 4.3 17.0 21.5 7.2 8.5 6.2 5.7 9.6 6.3 6.7 2.4 7.4 10.3 18.6 3.1 11.0 3.8 12.7 1.9 9.0 16.1 8.2 5.5 5.1 7.7 33.2 3.0 10.2 5.4 8.9 30.7 8.9 5.3 4.6 14.9 0.9 49.0 5.2 2.6 8.5 8.5 0.0 5.4 49.4 9.3 0.0 0.0 1.4 9.4 1.2 1.0 0.1 3.3 1.2 1.7 4.0 3.9 2.0 2.0 2.1 33.5 0.0 13.8 5.7 25.7 0.6 5.5 3.2 2.5 2.8 9.6 3.1 4.9 1.2 28.7 47.8 0.6 5.6 2.2 1.8 15.4 0.4 0.1 3.3 0.6 0.0 11.6 1.5 0.1 2.9 1.1 1.4 1.9 3.7 0.6 7.4 7.7 3.1 5.6 1.3 7.3 17.3 0.3 0.0 2.0 2.7 0.1 0.0 0.0 0.8 14.0 34.0 28.8 4.5 49.4 0.0 6.9 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 12.1 0.0 9.3 0.1 0.0 1.4 10.5 16.2 1.7 7.5 9.6 6.3 18.6 3.1 16.1 14.9 LPCAT3 "C3F, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976186-7018510 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 85.5;liver: 78.2" "Cell line enhanced" "Detected in all" "RT4: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.74e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" "unprognostic (3.86e-1)" "unprognostic (2.40e-2)" "unprognostic (6.90e-2)" "unprognostic (1.88e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-1)" "unprognostic (2.58e-2)" "prognostic favourable (4.89e-5)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.23e-1)" 16.4 24.4 4.2 8.8 5.0 8.1 15.1 15.7 5.4 7.9 37.5 6.1 8.1 43.4 8.2 7.8 13.6 9.1 11.3 20.2 4.1 2.7 37.3 78.2 20.3 17.9 5.2 5.3 13.9 38.7 4.6 9.4 29.0 4.8 13.7 17.2 8.3 22.2 8.2 19.4 13.3 85.5 12.4 4.9 11.3 22.8 7.6 4.0 14.1 14.6 10.3 13.7 15.7 8.5 5.3 13.9 32.3 33.7 11.5 10.8 12.4 6.2 11.5 5.0 13.9 35.0 16.5 10.7 3.6 15.3 9.9 16.9 24.4 32.3 6.7 2.0 5.8 15.7 5.9 13.2 7.7 16.5 7.2 13.6 10.2 21.9 7.5 7.0 14.5 26.1 7.7 9.5 4.7 9.2 7.2 4.9 6.4 9.4 8.5 8.6 16.6 6.7 9.0 7.1 6.9 12.1 48.4 4.3 4.2 21.7 33.5 2.4 3.4 9.8 3.8 6.2 9.2 10.7 2.6 6.1 4.3 9.9 7.7 7.4 5.3 13.9 20.8 32.3 8.6 30.0 10.0 5.0 9.0 9.7 13.9 5.3 8.5 8.7 20.0 11.5 33.7 7.9 10.8 12.4 4.2 5.0 15.7 5.4 4.1 2.7 5.2 5.3 4.8 4.0 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358618-34367278 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavourable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 9.7 5.3 20.1 9.6 35.1 5.0 11.0 38.6 32.2 11.9 30.5 4.3 3.5 25.3 8.0 8.6 17.7 16.4 19.0 17.1 14.2 21.0 4.9 1.8 7.8 7.2 13.2 18.2 9.6 6.8 6.4 6.1 4.6 28.9 5.7 30.0 2.9 6.4 8.3 6.1 15.2 23.8 14.4 7.1 8.5 33.1 2.6 13.1 4.5 4.4 4.5 9.3 15.4 14.2 2.6 6.2 4.7 1.8 2.1 9.4 1.0 5.5 13.3 6.6 5.3 18.1 18.5 3.2 7.8 13.3 7.5 10.3 4.8 15.1 5.0 16.4 10.9 45.3 5.8 14.8 3.3 10.2 3.2 5.0 5.6 4.6 3.7 5.4 5.2 13.7 6.7 7.1 9.2 12.2 3.3 9.9 13.9 5.4 4.7 10.6 6.6 10.6 5.9 7.5 10.2 16.4 13.4 5.2 4.0 4.7 6.3 3.0 4.9 7.3 15.1 13.9 8.5 21.9 7.4 12.1 9.5 1.7 10.4 15.1 3.2 0.1 1.1 4.5 3.9 1.4 9.4 2.3 4.6 6.0 1.8 2.6 2.8 2.5 4.7 2.1 1.8 6.2 7.3 1.0 20.1 35.1 38.6 32.2 14.2 21.0 13.2 18.2 28.9 13.1 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753118 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 82.4" "Cell line enriched" "Detected in some" 8 "NTERA-2: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.9 0.8 2.2 0.8 3.2 1.8 1.4 0.7 1.1 0.9 4.2 3.0 0.8 3.7 0.5 1.2 0.5 0.9 2.3 0.6 3.1 4.2 0.6 3.3 1.0 0.5 2.9 2.4 1.0 2.9 0.3 1.0 0.3 8.9 1.6 0.4 82.4 0.5 1.6 2.3 1.4 11.1 0.3 7.0 0.7 0.9 2.9 3.1 0.0 4.9 0.2 0.6 0.5 0.7 0.9 3.7 2.0 4.5 0.6 0.3 3.9 0.6 0.5 0.4 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.8 0.6 0.1 0.1 0.2 0.5 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.3 16.1 0.0 0.1 0.0 0.1 1.9 0.5 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.4 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.2 0.5 1.0 4.5 0.4 0.3 1.6 0.3 0.5 0.3 0.3 3.7 0.9 0.3 0.3 2.0 0.6 0.5 0.5 0.2 3.9 2.2 3.2 0.7 1.1 3.1 4.2 2.9 2.4 8.9 3.1 LRRK1 "FLJ23119, KIAA1790, RIPK6, Roco1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919215-101078254 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.3" "Cell line enhanced" "Detected in many" "Daudi: 23.1;Karpas-707: 17.0;U-266/84: 15.4;U-698: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.2;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA010537: AB_1079283" "unprognostic (3.74e-2)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-1)" "unprognostic (6.68e-2)" "unprognostic (6.35e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (3.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.95e-2)" "unprognostic (8.50e-2)" "prognostic unfavourable (5.71e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.25e-2)" 6.1 1.9 4.5 26.3 3.9 6.5 5.0 2.1 8.1 6.4 8.0 5.9 2.2 2.9 7.9 6.0 5.4 7.1 4.2 3.4 4.0 1.5 2.7 1.0 4.7 15.0 4.5 4.0 6.3 5.3 2.8 2.3 4.4 2.5 7.1 6.5 2.8 7.7 6.8 1.6 7.3 8.5 5.7 3.7 11.1 3.9 5.1 3.4 1.2 3.5 2.1 17.4 7.5 6.7 2.3 3.3 3.2 1.1 0.0 0.0 0.1 0.8 4.7 0.0 0.0 7.3 7.5 0.0 2.8 2.1 2.6 1.8 0.8 2.1 23.1 1.0 7.7 4.7 0.6 0.5 1.3 0.4 1.1 7.0 1.0 0.0 0.5 3.7 5.4 5.9 1.0 1.7 1.5 4.7 1.1 17.0 0.5 0.0 0.0 2.3 0.2 2.0 1.6 0.4 6.3 0.0 0.0 0.0 1.6 1.8 2.7 5.3 0.3 4.5 5.4 0.0 0.8 1.0 0.0 8.7 15.4 15.0 0.3 0.5 4.3 0.0 0.7 3.2 0.0 0.3 0.0 2.3 0.0 0.0 0.9 1.5 0.0 0.0 0.8 0.0 1.1 3.3 0.0 0.1 4.5 3.9 2.1 8.1 4.0 1.5 4.5 4.0 2.5 3.4 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell line enhanced" "Detected in some" "A549: 9.7;ASC TERT1: 10.0;BJ hTERT+: 5.6;RPTEC TERT1: 10.7" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favourable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.7 0.1 0.0 3.9 10.0 0.1 2.1 5.6 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.4 0.0 0.7 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 0.6 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.6 0.0 0.2 2.7 2.8 2.2 1.4 1.1 1.1 1.2 0.7 0.0 0.0 0.0 2.3 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 LRSAM1 "CMT2P, FLJ31641" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451486-127503501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favourable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favourable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 9.5 13.6 15.6 10.1 17.2 15.3 9.2 24.2 22.6 10.7 18.0 15.3 10.9 10.8 12.6 17.6 12.3 11.0 11.9 18.7 13.3 17.3 11.2 15.6 11.7 11.5 13.5 22.7 16.0 9.6 17.6 11.8 9.2 17.9 13.6 8.6 10.2 11.9 13.7 20.4 28.3 11.1 16.0 18.7 12.6 12.2 6.1 13.9 5.5 11.6 9.6 11.5 17.2 12.9 4.1 5.4 17.4 6.6 1.3 4.8 3.2 5.7 8.7 5.3 10.1 8.9 8.8 8.3 5.4 6.7 8.3 6.2 10.0 5.6 9.8 5.5 7.5 18.9 6.4 11.3 3.3 10.4 4.9 5.3 11.3 8.7 7.1 5.8 11.2 5.1 9.3 5.7 10.9 8.9 4.7 10.2 3.6 14.4 4.1 5.1 5.0 8.8 6.7 4.7 15.3 9.0 5.0 9.7 8.0 3.5 12.0 7.0 24.6 3.1 10.4 5.6 5.7 7.0 3.6 11.3 8.4 1.6 9.2 5.4 2.9 14.6 4.9 17.4 4.4 6.6 4.8 4.1 3.0 3.7 5.4 3.1 1.5 2.0 5.7 1.3 5.5 4.6 2.4 3.2 15.6 17.2 24.2 22.6 13.3 17.3 13.5 22.7 17.9 13.9 LRTOMT "CFAP111, COMT2, DFNB63, LRRC51" ENSG00000184154 "Leucine rich transmembrane and O-methyltransferase domain containing" "Q8WZ04, Q96E66" 11 72080331-72110782 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 49.8;testis: 47.8" "Cell line enhanced" "Detected in many" "T-47d: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favourable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" 3.5 3.7 10.6 2.0 11.1 2.1 7.1 3.7 8.9 7.1 4.2 14.0 6.1 3.2 6.0 13.6 3.5 49.8 5.3 2.6 8.8 7.6 9.0 6.2 6.2 2.6 7.7 8.5 8.5 7.0 7.1 8.9 4.4 10.6 7.5 6.2 7.3 4.3 4.7 5.2 4.5 2.5 4.8 7.7 3.2 3.6 47.8 8.9 3.1 9.3 2.4 3.5 3.5 2.6 4.3 4.2 9.2 2.9 10.1 6.2 2.0 2.6 9.8 6.2 5.0 5.4 4.8 1.5 3.1 2.5 2.8 2.5 4.7 14.3 3.4 4.8 5.3 5.3 4.4 7.5 3.2 6.4 4.3 2.5 4.5 3.3 0.9 2.0 2.7 2.1 3.8 4.3 3.3 1.0 2.7 5.3 4.1 9.4 6.0 4.0 3.1 2.6 7.3 6.3 5.2 11.0 3.2 5.8 4.5 6.1 14.1 7.5 27.8 2.4 4.7 3.0 4.2 8.0 2.1 5.7 6.2 4.0 2.9 1.7 3.3 2.3 2.9 5.0 3.1 2.8 3.2 4.2 3.3 2.6 1.7 4.3 3.0 3.0 9.2 10.1 1.8 4.2 6.2 2.0 10.6 11.1 3.7 8.9 8.8 7.6 7.7 8.5 10.6 8.9 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503638-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1" "Cell line enhanced" "Detected in some" "HEL: 5.3;NB-4: 10.3;RH-30: 5.0;THP-1: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 8.3;plasmacytoid DC: 7.0" "Group enriched" "Detected in many" 10 "dendritic cells: 7.0;T-cells: 8.3" "Low region specificity" "Detected in many" HPA059545 Uncertain Approved Vesicles Vesicles "HPA059545: " "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 1.0 0.5 0.5 5.1 1.6 3.1 0.5 2.0 3.2 0.6 8.2 0.5 1.9 10.6 1.3 1.1 1.2 0.3 2.0 2.2 0.5 0.1 3.5 4.3 15.1 0.6 0.5 0.5 1.0 0.5 1.0 0.7 8.9 0.5 0.7 4.8 4.3 11.7 0.5 2.0 0.9 10.7 0.5 0.5 5.5 8.3 2.4 0.8 0.5 0.7 0.5 2.2 0.6 0.7 0.7 7.0 0.0 0.0 0.0 8.3 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.6 0.9 1.3 2.4 0.0 0.0 0.1 0.7 0.0 2.9 0.0 0.4 0.2 1.4 5.3 0.0 0.0 2.3 0.0 0.0 0.4 0.4 0.0 0.1 0.0 2.0 0.0 2.0 0.0 0.0 10.3 0.4 0.2 0.2 5.0 0.1 0.0 0.0 0.5 3.3 0.1 0.2 0.0 0.2 15.8 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.6 0.0 8.3 0.7 0.5 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.2 0.5 1.6 2.0 3.2 0.5 0.1 0.5 0.5 0.5 0.8 LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol Cytosol "CAB034164: AB_2180094, HPA029143: AB_10671360, HPA055604: " "unprognostic (3.67e-2)" "unprognostic (7.07e-2)" "unprognostic (7.78e-2)" "unprognostic (3.99e-1)" "unprognostic (1.42e-2)" "unprognostic (3.66e-3)" "unprognostic (5.38e-2)" "unprognostic (5.40e-2)" "unprognostic (9.98e-2)" "unprognostic (4.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (9.87e-2)" "unprognostic (1.72e-1)" "unprognostic (8.22e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" 17.9 15.1 10.3 12.4 19.8 21.2 17.9 19.9 23.2 16.6 14.7 17.8 12.1 12.4 16.5 15.4 15.2 14.5 10.8 13.1 12.0 10.6 14.1 19.3 12.0 15.7 19.6 14.2 16.4 23.7 18.4 22.6 29.0 28.7 19.0 15.6 9.7 16.1 12.6 22.5 14.8 17.1 13.4 17.4 16.7 15.4 20.7 15.8 23.0 17.6 14.6 14.9 16.6 14.7 7.8 6.2 12.2 11.9 8.6 8.4 3.3 12.6 5.5 11.3 5.1 9.7 13.3 11.5 10.7 8.7 9.2 12.8 7.6 10.6 8.3 5.2 9.5 6.5 12.0 8.8 16.8 9.7 8.3 24.8 7.5 6.0 7.3 8.2 9.7 9.2 7.9 13.1 10.9 9.7 20.2 20.0 10.5 3.9 5.3 8.0 16.2 6.5 7.1 22.7 17.4 10.4 10.9 6.2 12.9 12.3 9.4 10.7 9.6 11.6 12.8 8.1 15.2 10.9 9.0 16.4 15.3 11.8 12.7 17.9 9.6 12.2 6.4 9.5 8.4 9.8 7.0 7.8 5.8 5.6 6.2 7.1 6.2 4.7 11.3 8.6 11.9 3.9 6.1 3.3 10.3 19.8 19.9 23.2 12.0 10.6 19.6 14.2 28.7 15.8 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879813-56014168 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.9" "Cell line enhanced" "Detected in many" "HEL: 56.8;HMC-1: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" 11000000 "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavourable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 8.8 6.8 4.5 34.0 6.3 33.6 11.1 9.5 4.1 5.3 10.5 5.8 7.2 15.6 3.4 7.8 7.2 6.7 13.7 8.9 4.8 3.6 6.1 13.8 34.6 70.9 7.7 2.1 5.3 9.8 3.1 4.9 19.1 5.6 5.7 6.6 6.3 14.9 8.5 2.7 3.4 16.2 6.6 8.5 69.4 7.4 3.6 5.1 3.8 9.4 5.3 25.8 10.7 7.5 8.4 9.2 36.8 26.5 1.9 0.9 2.7 12.6 7.5 1.7 0.3 0.1 0.0 13.7 9.7 14.2 6.1 4.3 5.2 4.4 12.2 4.3 3.8 5.9 7.1 7.2 5.2 19.8 7.1 56.8 2.3 1.8 1.9 5.7 57.7 0.3 2.5 0.1 4.4 8.2 30.0 26.5 0.9 0.7 0.0 6.0 10.9 0.8 0.9 2.8 1.5 3.9 6.0 1.1 22.0 4.8 0.0 2.0 1.1 13.4 9.6 0.0 2.8 0.0 4.4 8.9 3.2 27.6 0.6 11.3 0.4 2.1 7.2 12.3 0.9 16.8 0.7 8.2 0.2 0.3 6.4 8.4 0.1 0.4 36.8 1.9 26.5 9.2 0.0 2.7 4.5 6.3 9.5 4.1 4.8 3.6 7.7 2.1 5.6 5.1 MAK "dJ417M14.2, RP62" ENSG00000111837 "Male germ cell associated kinase" P20794 6 10762723-10838555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 38.1;testis: 19.3" "Cell line enhanced" "Detected in some" "HDLM-2: 4.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 7 "pons and medulla: 10.6" "Cell type enriched" "Detected in single" 13 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "unprognostic (1.23e-3)" "unprognostic (8.77e-3)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-3)" "unprognostic (1.97e-2)" "unprognostic (2.53e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (6.73e-2)" "unprognostic (6.59e-5)" "unprognostic (1.55e-1)" "unprognostic (8.40e-2)" "unprognostic (7.71e-3)" "unprognostic (4.59e-2)" 0.6 0.3 0.7 0.7 1.5 1.4 0.7 0.4 0.4 0.8 0.2 3.5 0.3 0.2 0.6 2.9 0.3 8.6 1.0 0.3 1.1 1.2 0.3 0.2 1.8 3.7 0.2 0.1 2.2 0.5 9.3 3.6 0.2 10.6 0.5 0.0 38.1 0.5 0.4 0.2 1.1 0.4 0.1 0.7 1.4 0.5 19.3 0.7 0.0 0.6 0.4 0.2 0.2 1.2 0.6 0.4 11.7 0.8 0.3 0.7 0.1 3.0 0.9 1.8 1.8 0.1 0.0 1.7 0.0 0.2 1.0 1.0 1.3 1.7 0.9 0.7 0.0 0.5 0.6 0.3 0.4 4.7 1.9 0.7 0.7 1.2 0.0 3.2 2.9 0.1 0.0 0.2 0.3 0.0 1.6 0.6 0.1 0.4 0.4 1.9 0.8 0.4 0.6 0.8 0.3 0.1 0.4 1.9 0.9 0.1 0.5 0.1 1.1 0.3 0.2 0.7 1.1 0.2 1.1 0.5 0.1 0.4 0.5 0.6 1.0 0.5 0.8 0.9 0.4 0.5 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.7 11.7 0.3 0.8 0.4 0.1 0.1 0.7 1.5 0.4 0.4 1.1 1.2 0.2 0.1 10.6 0.7 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.1 15.6 31.5 13.1 19.0 14.3 18.2 24.1 20.6 26.2 23.4 23.5 27.3 30.5 29.9 19.8 29.6 29.4 35.2 30.8 24.5 17.5 9.8 16.4 12.7 15.4 12.9 14.6 11.0 21.8 18.9 28.1 20.4 17.3 39.0 38.1 12.8 10.3 16.8 16.1 13.7 11.7 19.5 27.1 25.4 14.3 19.4 10.8 19.5 15.3 20.2 13.8 11.0 28.1 34.1 20.9 24.0 35.7 24.2 43.0 19.4 36.0 22.8 15.9 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol Cytosol "CAB003835: AB_562312, HPA051993: " "unprognostic (4.39e-1)" "prognostic favourable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favourable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favourable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.2 40.0 21.9 30.7 30.3 36.6 21.9 23.9 32.0 32.7 29.7 34.6 19.7 31.0 22.6 27.2 26.2 17.1 25.5 25.4 26.3 20.8 11.3 21.8 38.2 46.5 20.8 23.9 40.4 24.9 22.9 30.6 28.9 21.6 61.3 27.5 45.4 41.1 29.2 25.1 29.1 31.5 14.4 35.4 28.5 23.3 29.7 29.6 21.9 30.4 74.5 23.4 35.7 25.5 26.9 23.3 68.6 36.8 61.7 37.3 21.7 41.7 37.5 45.9 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.6 22.0 2.9 13.3 17.8 11.4 11.1 33.6 36.5 26.8 24.7 24.3 14.0 19.6 13.7 52.5 21.5 9.3 29.8 19.1 20.3 17.0 11.4 12.6 22.0 5.5 14.9 23.4 8.8 8.5 36.5 11.0 12.0 2.2 9.8 22.3 21.5 7.4 14.2 8.4 12.6 15.5 18.9 14.5 15.1 22.9 8.0 2.8 12.4 13.4 23.3 6.7 5.1 10.9 25.5 20.8 27.2 21.6 12.3 6.2 25.2 24.6 12.9 13.1 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 17.9 15.5 20.4 10.5 11.3 14.7 13.0 12.3 16.2 14.0 13.4 9.2 6.2 7.5 10.0 19.1 12.1 17.7 17.1 21.1 13.2 20.8 8.3 9.1 17.3 13.3 7.9 12.6 12.1 17.0 16.4 17.2 12.7 8.8 4.4 17.6 6.7 9.6 7.4 11.9 7.6 11.8 22.9 5.1 19.2 11.6 4.1 12.1 14.2 7.6 11.8 9.6 5.8 11.6 6.9 10.7 9.5 14.5 8.7 9.7 5.9 13.0 6.3 10.0 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favourable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.5 14.6 8.8 10.3 13.0 22.8 6.9 5.5 11.2 10.4 11.4 5.8 9.9 9.1 11.7 9.2 8.3 14.9 8.8 8.6 13.1 14.9 12.3 10.9 6.3 16.4 7.4 7.7 15.6 11.7 7.5 17.1 13.7 10.8 15.2 8.6 7.1 12.1 8.8 12.3 7.1 12.0 10.2 15.1 6.3 10.1 5.5 8.6 6.2 9.2 22.0 11.5 14.6 11.4 10.7 7.1 7.4 7.4 21.5 25.3 10.6 14.4 17.0 7.7 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell line enhanced" "Detected in many" "A549: 23.9;HUVEC TERT2: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favourable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favourable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 23.9 10.8 13.0 4.7 2.5 1.6 0.1 3.5 1.0 1.5 0.7 1.1 0.6 8.8 0.5 1.2 3.7 0.5 0.3 0.8 1.9 0.1 6.7 6.7 4.6 1.0 0.9 11.9 0.3 0.3 0.0 17.2 0.0 1.7 0.0 0.1 12.5 0.4 7.6 4.4 4.5 1.1 0.3 4.8 3.3 4.8 7.3 1.0 0.9 2.2 3.3 1.3 3.0 1.3 1.5 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: " "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favourable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favourable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.7 7.3 6.4 10.4 5.1 5.0 11.9 8.4 4.1 5.7 6.0 10.5 7.8 15.2 13.6 4.4 11.7 5.5 6.4 2.2 12.1 27.4 10.7 9.7 7.8 6.6 9.9 13.6 5.7 8.4 4.5 5.2 5.2 15.6 20.0 3.3 6.7 14.2 24.2 11.2 16.5 14.1 6.9 15.4 5.1 10.7 11.7 11.8 5.7 10.1 11.7 10.8 11.4 7.7 17.5 10.0 12.3 11.3 29.0 13.4 14.3 8.7 14.7 7.0 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.0;THP-1: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol Cytosol "CAB004500: AB_627926, HPA046509: " "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.4 3.9 6.2 4.1 1.0 0.8 10.4 1.2 1.7 3.9 5.5 18.4 4.9 5.8 0.4 1.5 3.4 5.1 2.3 5.4 2.0 2.2 3.2 1.7 8.6 2.5 5.1 9.0 1.0 2.5 1.2 1.9 1.7 2.8 10.5 1.0 2.8 3.5 6.9 2.8 0.5 5.6 4.4 19.9 6.8 6.8 2.6 27.0 3.8 4.8 11.0 13.2 25.2 4.9 0.3 3.3 1.4 2.3 7.7 3.9 11.1 0.6 3.0 6.6 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191744-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favourable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favourable (2.13e-4)" 7.7 7.0 29.6 4.7 22.8 3.7 2.2 14.3 32.0 3.3 3.4 5.3 1.8 4.4 4.5 1.8 3.7 3.1 4.0 8.2 28.2 11.2 4.7 2.1 4.2 4.6 11.5 9.4 4.3 8.1 4.7 5.2 3.7 9.0 4.6 2.0 2.4 6.9 4.8 22.9 5.6 5.0 4.0 5.3 6.7 6.2 6.6 7.1 2.3 3.3 2.6 2.4 3.8 5.4 0.8 0.0 0.0 0.2 0.0 0.9 0.0 6.2 7.5 2.3 5.5 2.2 1.3 6.5 4.4 2.2 2.0 2.1 1.7 1.8 5.7 4.6 1.5 2.0 0.9 2.2 0.3 10.9 7.1 1.5 3.2 1.7 4.2 1.2 3.7 1.2 5.4 2.2 1.5 1.9 5.4 9.8 0.6 3.7 4.7 2.3 2.8 4.9 5.9 2.5 3.4 1.8 4.0 7.8 11.3 5.1 1.8 10.3 2.5 2.3 3.1 5.3 5.1 7.8 8.4 13.0 7.5 2.5 6.2 2.4 7.7 0.0 0.1 0.0 0.4 0.2 0.0 0.8 0.2 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 29.6 22.8 14.3 28.7 28.2 11.2 11.5 9.4 9.0 7.1 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597755-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 75.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 23.2 10.8 11.4 23.7 21.2 14.2 27.4 7.9 13.8 8.6 15.8 29.8 6.1 31.9 11.0 8.1 14.7 11.6 12.0 11.6 13.3 8.1 16.1 31.2 21.1 14.4 30.9 8.2 8.4 12.5 8.3 10.3 14.7 16.7 13.4 8.2 15.4 13.5 9.5 11.9 13.7 31.9 8.6 17.7 28.8 16.9 8.6 19.0 8.9 13.6 7.6 12.7 8.9 75.8 2.3 7.6 13.8 12.0 1.8 3.5 5.6 16.5 14.6 7.9 8.4 2.5 3.2 8.1 6.4 4.5 7.7 5.3 14.6 16.0 6.2 23.7 5.0 14.4 4.7 6.9 2.8 13.6 6.0 17.5 10.0 17.4 7.0 10.0 26.5 5.0 6.7 5.7 5.2 21.5 7.5 12.5 4.0 20.4 11.7 18.9 8.6 18.7 19.5 5.1 12.6 7.2 14.3 7.1 8.0 7.5 21.8 37.5 17.4 16.3 23.9 11.8 12.8 17.2 11.3 8.0 9.0 5.5 13.8 11.6 27.3 4.3 7.7 9.2 2.4 12.0 2.4 2.0 2.6 3.5 7.6 2.3 2.0 1.5 13.8 1.8 11.7 2.3 1.4 5.6 11.4 21.2 7.9 13.8 13.3 8.1 30.9 8.2 16.7 19.0 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell line enhanced" "Detected in many" "ASC diff: 28.4;HHSteC: 27.1;HSkMC: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 3.4;monocytes: 1.7;T-cells: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "HPA039936: AB_10795239, HPA071996: " "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favourable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavourable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 8.0 8.7 12.3 5.8 16.0 3.0 5.1 40.3 20.6 14.1 6.1 7.0 7.8 3.6 15.1 5.8 4.6 11.5 16.1 4.2 9.4 7.7 4.5 1.4 8.8 4.5 6.4 14.7 13.7 1.8 3.0 12.7 7.3 10.8 5.9 4.6 9.5 2.4 13.5 1.2 4.5 4.1 16.9 5.3 5.3 3.9 6.5 7.4 2.7 4.3 1.4 3.2 11.3 6.4 0.3 0.6 3.4 1.7 0.6 2.8 0.5 0.2 7.5 4.7 7.3 28.4 15.2 0.6 5.1 9.6 5.6 5.6 0.1 0.9 1.7 2.9 5.4 0.0 2.1 3.4 2.2 2.5 2.6 1.8 3.8 0.0 27.1 0.0 1.9 27.0 2.4 7.6 4.0 8.7 0.0 8.1 5.3 3.3 1.8 0.4 1.6 2.8 2.6 3.2 0.4 2.8 0.0 4.7 6.4 2.7 3.5 7.2 2.4 4.7 6.4 5.4 5.8 2.4 1.3 3.3 3.7 0.0 8.7 3.3 5.2 0.0 1.7 0.0 1.5 1.3 2.8 0.3 2.1 2.3 0.6 0.0 0.9 1.2 3.4 0.6 0.4 0.3 0.4 0.5 12.3 16.0 40.3 20.6 9.4 7.7 6.4 14.7 10.8 7.4 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489097 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavourable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favourable (1.11e-4)" "prognostic unfavourable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 9.8 24.8 21.7 8.7 22.2 9.5 15.1 16.4 26.1 12.9 16.9 18.4 10.5 16.8 12.9 42.1 15.2 14.6 13.1 8.1 19.2 18.6 21.9 20.7 15.2 7.4 23.2 17.1 16.5 24.9 20.9 24.5 9.1 21.8 14.5 18.9 18.6 26.2 11.4 3.3 9.8 23.4 12.1 26.4 8.7 16.4 12.9 15.8 4.4 18.6 8.3 10.3 12.5 11.5 23.7 21.5 21.1 13.2 11.5 17.4 7.8 29.1 5.8 11.3 0.3 10.3 12.7 6.6 6.7 4.6 10.9 13.2 11.2 11.0 0.2 23.0 12.2 16.7 0.3 15.5 19.4 32.4 15.0 0.1 7.9 9.2 11.2 15.3 8.4 11.5 13.6 9.3 11.7 12.1 0.3 23.7 9.7 9.1 1.8 7.2 13.0 13.7 0.2 13.5 16.0 19.2 7.6 18.6 12.4 11.3 17.1 23.2 25.8 8.6 8.0 9.0 11.7 16.2 14.5 12.1 15.6 9.6 13.2 7.8 14.7 6.4 13.2 5.1 10.3 12.2 15.8 23.7 12.4 12.8 21.5 19.0 17.4 16.8 21.1 11.5 8.6 9.4 4.8 7.8 21.7 22.2 16.4 26.1 19.2 18.6 23.2 17.1 21.8 15.8 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263121-45317040 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 22.0;HDLM-2: 22.6;U-251 MG: 22.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_10600302, HPA027270: AB_10600884" "unprognostic (1.05e-2)" "prognostic favourable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 3.7 3.4 3.0 14.7 4.0 3.4 2.7 4.9 3.6 5.0 7.3 4.5 3.5 6.0 5.5 3.3 6.8 4.2 6.2 4.5 3.0 4.4 5.1 4.9 12.0 3.0 0.6 3.5 5.7 3.5 7.7 1.5 4.6 5.2 3.5 4.3 7.5 4.8 14.5 6.1 9.6 5.2 4.1 8.4 4.0 4.5 4.5 7.1 2.2 6.9 18.0 4.9 2.8 9.5 4.8 7.7 3.6 5.6 5.2 2.3 9.4 22.0 2.2 3.9 1.5 3.7 5.6 2.6 1.8 8.3 5.1 3.4 11.6 4.2 13.3 2.7 6.6 1.0 3.5 4.3 22.6 1.7 0.9 6.0 1.5 4.0 0.7 4.4 5.8 2.2 4.1 2.2 1.6 1.8 18.0 4.2 3.4 3.9 1.5 1.2 3.1 5.2 6.7 9.5 6.0 1.9 2.3 1.9 4.0 2.7 2.8 1.7 0.4 3.5 3.8 5.9 3.2 22.1 17.2 6.4 2.2 2.1 2.4 5.1 1.5 3.4 1.6 3.5 3.6 2.0 7.6 2.4 2.5 2.3 9.5 2.6 2.5 7.7 5.6 2.2 4.8 5.2 2.3 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 13.2" "Cell line enhanced" "Detected in some" "A549: 3.4;HAP1: 8.6;HEK 293: 7.2;HEL: 2.9;REH: 4.4" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "pons and medulla: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004006 Approved Vesicles Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.1 17.3 0.5 0.4 0.3 0.5 0.1 2.3 0.1 0.1 0.1 5.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.5 3.6 0.1 0.5 0.0 0.1 0.0 1.3 4.1 0.4 5.7 0.0 13.2 0.1 0.0 4.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 2.6 0.1 2.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.4 7.2 2.9 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.2 2.2 0.9 4.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.3 0.1 0.4 0.5 0.1 0.0 13.2 0.0 MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964491-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.3;fallopian tube: 23.9" "Group enriched" "Detected in some" 5 "RPMI-8226: 4.0;U-266/70: 2.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "pons and medulla: 18.3" "Cell type enriched" "Detected in single" 6 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 20.2" HPA011388 Uncertain Cytosol Cytosol "HPA011388: AB_1848822" "unprognostic (7.12e-3)" "unprognostic (6.55e-3)" "unprognostic (6.96e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (2.83e-4)" 0.1 0.2 1.7 0.2 6.2 0.1 0.1 0.0 0.5 1.1 0.2 7.3 0.0 0.2 1.0 6.7 0.2 23.9 0.1 0.1 2.9 3.8 0.2 0.2 5.6 0.2 0.5 1.5 7.3 0.1 0.1 1.0 0.1 18.3 0.3 0.2 0.0 0.2 0.2 0.3 0.2 0.2 0.1 0.5 0.2 0.2 7.6 3.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 4.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.7 6.2 0.0 0.5 2.9 3.8 0.5 1.5 18.3 3.1 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021540: " "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 18.5 14.5 13.7 20.1 14.5 41.0 22.6 20.1 16.3 16.6 19.6 12.7 18.9 18.8 19.8 18.0 13.4 15.9 18.6 13.3 12.5 10.2 15.5 27.6 20.0 28.5 17.9 13.0 20.3 15.4 23.8 21.2 13.9 12.3 13.6 13.1 12.2 18.1 25.5 24.5 19.4 22.5 18.1 14.9 17.0 18.0 14.9 14.3 25.8 22.5 13.7 16.8 17.1 20.3 3.1 5.1 13.6 2.9 2.3 2.1 1.1 16.3 7.0 5.6 5.6 7.8 10.4 9.3 10.2 11.1 10.1 8.2 8.3 7.3 10.8 17.6 14.5 13.9 8.9 6.8 11.3 27.0 6.9 10.0 12.6 7.3 9.1 10.0 21.7 9.3 7.6 12.2 15.0 4.6 4.7 21.6 9.9 5.9 11.7 7.1 5.7 9.1 7.7 10.5 8.0 4.1 15.3 11.1 5.9 14.8 9.1 9.2 5.9 7.7 10.6 19.8 18.6 9.1 13.8 22.4 16.1 11.1 9.5 6.6 8.5 4.0 2.9 2.0 1.7 1.8 2.1 3.1 1.6 1.7 2.4 2.6 1.9 2.0 13.6 2.3 2.2 5.1 1.4 1.1 13.7 14.5 20.1 16.3 12.5 10.2 17.9 13.0 12.3 14.3 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268010 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 96.1" "Cell line enhanced" "Detected in many" "U-138 MG: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 13.7" "Group enriched" "Detected in many" 5 "dendritic cells: 13.7;monocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 21.7 5.0 2.9 7.4 3.3 0.8 9.2 2.8 3.1 25.7 24.8 2.1 10.7 3.1 30.2 15.4 26.2 13.1 14.9 52.5 3.5 3.0 2.4 8.5 7.5 2.5 4.5 3.0 21.7 4.4 22.6 3.1 6.9 4.2 25.6 5.4 11.5 6.7 15.8 96.1 5.8 8.0 68.4 4.7 3.7 15.8 6.6 3.5 2.8 6.7 38.0 4.9 46.7 24.0 2.1 13.7 2.3 8.0 0.4 1.6 2.7 8.7 7.3 5.8 7.6 16.9 25.2 3.6 31.6 24.7 14.8 15.9 5.0 5.8 6.7 8.3 31.6 5.9 8.6 16.7 33.3 13.1 5.8 11.0 8.3 1.0 6.7 9.8 11.6 20.2 7.2 27.8 43.9 9.7 4.9 1.3 9.7 3.7 6.1 4.9 3.2 4.2 9.1 11.9 0.0 3.6 5.0 3.4 3.3 12.2 3.0 5.1 3.4 5.3 9.7 47.2 19.4 14.0 7.1 0.0 0.0 1.4 33.9 2.7 4.9 0.1 8.0 0.0 0.9 7.5 0.9 1.5 0.8 1.6 13.7 2.1 0.0 0.8 2.3 0.4 6.6 0.3 0.7 2.7 2.9 3.3 2.8 3.1 3.5 3.0 4.5 3.0 4.2 3.5 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327768-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.9" "Cell line enhanced" "Detected in many" "HEK 293: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.6 3.2 2.0 3.4 2.2 1.3 2.2 10.0 3.3 1.5 11.4 0.6 9.1 9.9 0.8 5.2 2.4 3.9 3.9 0.7 1.3 2.1 12.5 13.3 5.6 0.5 0.9 1.7 0.8 28.9 4.4 2.6 1.0 1.2 1.3 6.0 1.0 3.7 2.5 0.4 2.7 17.2 0.3 0.9 0.7 10.1 12.4 0.6 0.5 2.4 0.8 1.3 1.1 1.6 0.5 0.8 0.1 0.3 5.0 0.2 0.1 7.3 12.5 0.2 0.0 0.0 0.0 6.3 0.2 0.0 0.3 0.5 6.9 6.4 0.7 5.2 0.1 3.9 9.4 3.8 0.8 13.6 18.0 0.1 7.0 0.0 0.4 11.9 2.9 0.1 5.1 0.2 7.3 0.4 0.1 2.4 0.0 1.6 3.8 4.3 8.9 5.5 0.0 0.0 13.1 8.6 3.1 9.2 2.5 4.3 0.2 0.0 3.7 3.8 0.0 0.0 1.2 0.0 7.3 2.2 2.8 0.0 1.2 3.3 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.8 0.5 0.0 0.0 0.1 5.0 0.0 0.2 0.2 0.1 2.0 2.2 10.0 3.3 1.3 2.1 0.9 1.7 1.2 0.6 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm Nucleoplasm "CAB007764: AB_562314, HPA035410: , HPA035411: " "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.1 7.6 9.7 9.4 18.6 15.0 4.4 10.0 11.0 12.5 10.1 3.5 2.1 10.9 7.1 19.6 3.8 6.3 7.1 7.9 9.5 13.9 8.9 10.3 4.9 9.7 6.8 9.5 10.7 4.9 15.5 8.2 30.3 5.4 14.5 9.9 7.1 12.2 7.1 6.0 8.1 6.5 24.8 7.1 4.5 4.6 5.0 11.9 6.8 8.2 8.3 8.2 6.8 27.2 32.0 8.5 17.3 12.1 14.4 14.6 4.0 6.9 5.5 8.3 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.6 5.3 10.1 8.6 6.3 7.4 6.5 5.3 4.7 6.1 6.5 7.5 3.4 9.6 3.8 13.5 11.7 10.3 10.6 7.5 7.0 8.4 12.5 4.9 7.4 4.8 13.0 6.1 4.6 12.3 6.4 5.8 7.9 31.6 11.1 6.5 4.8 8.7 6.6 6.1 8.2 9.6 9.3 7.6 5.6 3.4 5.8 5.2 9.9 10.6 0.9 4.3 15.9 7.4 7.5 9.6 6.9 25.0 6.5 5.2 8.8 8.8 13.4 7.8 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557047-136792518 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 55.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol Cytosol "CAB007824: AB_598175, HPA063245: " "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favourable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavourable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 7.7 55.6 13.0 7.5 17.6 7.6 5.5 12.9 12.7 4.0 5.4 6.9 3.6 4.6 7.2 5.1 6.4 6.1 4.9 7.3 11.8 6.8 6.8 5.5 7.7 8.8 8.2 6.4 32.4 28.2 1.5 9.9 3.4 7.9 11.6 6.2 5.8 4.2 4.9 3.7 5.0 4.6 4.3 7.5 9.8 8.7 7.3 8.6 2.0 10.0 3.4 9.0 10.8 18.9 2.5 2.5 8.5 3.0 4.1 7.0 1.4 2.8 1.7 0.0 0.0 4.1 11.1 1.0 4.1 22.3 2.1 2.0 0.1 2.9 1.7 6.1 5.7 4.0 7.1 2.1 5.6 2.3 5.6 14.7 3.9 0.0 19.8 6.8 0.0 14.6 2.8 3.3 9.6 7.1 3.6 16.5 15.0 5.5 0.1 5.8 0.7 2.4 3.8 4.7 6.7 8.6 18.3 5.2 3.4 3.4 3.3 0.9 0.7 6.1 6.2 3.6 1.1 0.2 3.8 13.5 8.9 0.0 2.8 9.6 3.1 5.7 3.0 3.3 2.7 2.3 4.9 2.0 4.3 3.7 2.5 2.5 0.4 1.4 8.5 4.1 2.1 2.4 7.0 1.4 13.0 17.6 12.9 9.4 11.8 6.8 8.2 6.4 7.9 8.6 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366892 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: " "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.13e-4)" "prognostic favourable (7.26e-4)" "prognostic unfavourable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 37.5 6.3 7.4 6.9 8.6 1.3 22.1 12.6 8.3 19.9 9.0 2.7 8.9 3.3 13.1 10.3 25.7 12.8 12.4 14.9 6.2 2.6 13.6 5.0 21.7 5.5 11.4 1.9 11.7 8.3 8.2 15.8 7.3 9.8 13.9 5.9 15.7 11.5 9.7 6.3 63.9 6.2 16.0 11.7 8.7 9.0 6.7 7.0 0.6 12.0 16.1 14.3 14.3 18.3 2.7 3.3 5.1 6.9 1.1 7.6 2.4 7.4 6.9 6.2 6.9 8.7 15.3 1.6 9.3 5.4 7.0 5.3 2.0 10.0 0.1 8.3 14.1 11.8 2.1 6.5 3.5 6.2 5.1 0.5 16.0 3.1 2.7 0.5 0.6 12.2 15.9 7.3 2.6 4.7 2.3 4.1 11.1 18.4 0.3 8.4 1.9 5.7 2.7 4.1 1.7 10.5 7.8 2.3 3.4 9.8 8.6 7.3 4.6 6.4 9.8 17.6 7.4 19.7 4.8 3.3 4.1 0.1 15.6 6.1 5.1 1.8 1.5 5.1 5.3 3.3 7.6 2.7 5.5 5.9 3.3 2.3 4.4 3.6 2.4 1.1 6.9 0.0 5.6 2.4 7.4 8.6 12.6 8.3 6.2 2.6 11.4 1.9 9.8 7.0 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587045 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 15.5 17.6 19.6 17.3 26.3 10.3 21.6 27.5 27.3 21.1 16.4 15.7 15.8 12.5 23.1 23.6 15.2 15.5 17.6 22.2 20.5 17.5 15.9 15.5 20.0 22.2 22.9 16.4 25.0 13.5 25.8 25.6 23.6 20.7 21.2 15.3 12.4 17.0 23.3 24.3 18.7 14.7 19.4 23.0 23.3 14.7 13.8 21.7 28.2 20.3 10.8 21.9 17.2 18.9 14.2 15.9 19.4 17.7 18.2 22.1 13.6 7.7 6.9 20.1 17.2 14.7 19.7 14.2 15.6 18.1 14.1 17.8 8.8 7.5 17.3 10.0 16.9 8.3 12.6 12.2 24.0 8.8 13.4 15.4 9.5 11.7 15.4 17.1 11.9 16.2 14.9 13.7 16.9 13.2 30.8 14.2 20.1 9.5 7.9 14.5 16.5 8.7 13.7 36.1 8.4 11.8 8.7 10.2 14.5 10.9 7.6 11.8 7.5 30.5 12.6 11.5 7.3 10.5 14.5 12.7 11.3 7.5 17.6 18.8 16.8 15.5 12.7 19.4 15.1 17.4 16.8 14.2 14.5 14.4 15.9 10.5 16.5 16.0 12.5 18.2 17.7 9.8 22.1 13.6 19.6 26.3 27.5 27.3 20.5 17.5 22.9 16.4 20.7 21.7 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30433937-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.6" "Cell line enhanced" "Detected in many" "HMC-1: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavourable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 28.0 7.6 3.6 15.6 4.1 104.6 26.1 1.5 2.6 8.2 8.4 2.7 11.3 3.4 11.5 16.5 13.8 19.5 15.3 20.1 4.3 2.9 6.3 7.6 29.0 33.7 4.3 2.0 9.8 3.6 2.8 4.1 27.5 8.3 7.9 6.8 9.4 6.1 18.4 8.6 15.3 9.6 23.4 9.7 25.6 10.7 6.7 3.6 2.4 7.0 13.2 17.2 13.2 15.6 19.6 13.8 23.7 16.8 12.4 7.8 4.0 7.9 7.1 1.9 4.1 10.3 8.7 9.1 2.0 11.9 4.4 5.3 4.9 18.5 5.2 5.1 4.2 14.9 4.5 1.9 1.6 12.0 2.3 9.7 12.1 15.7 8.7 3.0 24.0 10.8 1.1 4.4 0.8 1.9 4.3 7.8 0.7 4.5 0.1 11.6 0.7 2.5 0.6 1.6 3.0 4.4 16.1 0.2 0.8 7.1 6.1 0.9 2.0 6.4 0.1 2.7 2.3 9.7 0.3 11.9 11.1 1.5 3.9 13.2 0.1 17.9 7.0 23.7 7.8 12.0 4.3 9.6 1.7 4.9 6.6 19.6 0.1 3.0 16.7 12.4 16.8 13.8 0.4 4.0 3.6 4.1 1.5 2.6 4.3 2.9 4.3 2.0 8.3 3.6 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell line enhanced" "Detected in many" "A-431: 17.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.5 2.2 5.8 2.0 9.2 1.4 2.8 20.1 16.5 2.4 3.1 1.8 0.4 3.0 1.1 3.4 10.1 2.2 1.5 1.2 5.7 7.1 3.1 2.4 3.9 2.6 5.9 5.9 1.4 4.3 6.8 4.7 2.8 12.8 2.0 3.1 3.1 3.2 1.3 1.9 7.8 2.9 0.7 1.6 1.9 3.4 10.1 1.8 0.6 5.3 3.2 6.8 2.0 3.9 2.3 0.5 1.3 0.2 1.1 1.4 0.3 17.7 8.2 1.6 2.0 0.0 0.0 5.5 0.3 0.2 1.7 1.5 5.9 6.8 3.6 2.4 0.1 8.4 5.2 10.0 1.8 2.4 1.5 0.2 2.9 3.9 0.2 0.4 0.8 0.1 5.5 1.2 10.4 0.0 1.3 0.8 0.4 7.1 2.8 0.4 3.5 3.8 1.0 3.1 0.7 3.9 8.2 11.3 2.4 5.1 6.1 1.0 5.5 0.6 0.0 0.0 7.2 0.0 2.8 1.9 4.3 1.9 2.7 0.3 1.0 0.5 0.2 0.8 0.6 0.1 0.1 1.0 0.6 1.0 0.0 2.3 1.0 0.7 1.3 1.1 0.2 0.5 1.4 0.3 5.8 9.2 20.1 16.5 5.7 7.1 5.9 5.9 12.8 1.8 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.2;intestine: 16.9;lymphoid tissue: 39.2" "Cell line enhanced" "Detected in some" "Daudi: 20.5;HDLM-2: 20.3;Karpas-707: 21.1;REH: 11.2;RPMI-8226: 12.7;U-266/70: 16.6;U-266/84: 16.3;U-698: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007419, CAB007754" Enhanced Uncertain "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favourable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favourable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 1.6 0.9 1.2 31.4 2.3 6.3 1.1 1.0 1.2 1.0 3.1 1.7 0.1 2.1 0.9 1.4 2.6 1.2 2.9 0.9 1.1 1.4 2.2 1.6 3.9 23.0 2.3 0.7 0.8 1.2 0.2 1.2 1.4 2.1 1.6 1.9 2.0 4.4 0.8 0.5 1.2 16.9 0.7 3.4 34.4 2.3 0.9 1.3 19.1 1.9 1.4 39.2 3.1 1.3 16.2 15.9 1.3 6.2 3.7 14.6 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.3 0.0 0.0 0.0 0.0 0.0 20.3 0.1 4.3 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 21.1 0.0 0.1 4.9 5.1 0.6 0.0 11.2 0.0 12.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 4.6 0.0 0.0 0.1 0.0 0.0 16.6 16.3 25.8 0.0 5.8 0.0 1.3 3.2 1.2 13.4 6.2 12.4 16.2 11.2 14.0 15.9 10.7 6.2 8.7 0.3 3.7 3.4 14.0 14.6 7.3 1.2 2.3 1.0 1.2 1.1 1.4 2.3 0.7 2.1 1.3 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784914-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavourable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 6.9 6.2 9.4 15.2 10.0 19.1 5.8 12.1 15.6 5.2 5.8 10.1 6.9 4.9 6.2 4.0 4.3 4.4 6.3 5.5 9.4 9.2 6.2 3.1 12.0 22.3 8.3 7.3 4.2 7.2 5.2 8.0 12.3 12.5 6.1 4.7 6.7 9.0 8.9 3.4 5.0 9.9 5.6 6.7 22.6 7.1 5.5 6.6 11.5 8.7 3.9 18.8 6.1 5.1 10.8 5.0 8.2 14.8 2.3 9.6 7.1 6.1 5.5 3.6 6.6 3.3 2.0 8.6 4.6 4.3 5.6 3.9 2.4 2.9 10.7 8.6 5.2 1.8 4.4 4.5 3.3 13.9 2.1 18.8 7.7 5.1 4.0 9.9 7.1 2.0 2.3 4.3 2.8 13.6 1.6 1.0 1.7 7.6 5.8 9.9 2.4 7.5 12.2 0.4 12.3 3.1 3.1 4.4 6.3 4.0 5.2 4.1 10.5 15.2 10.5 4.7 10.5 4.3 1.9 1.2 2.4 11.6 4.1 15.0 3.4 2.2 4.2 5.6 5.2 12.2 5.3 10.8 7.0 4.7 4.4 7.6 8.6 6.3 8.2 2.3 14.8 5.0 9.6 7.1 9.4 10.0 12.1 15.6 9.4 9.2 8.3 7.3 12.5 6.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437312 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 40.8;RT4: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 19.7 18.9 17.6 15.4 17.6 9.6 17.8 37.1 19.6 19.2 16.9 14.6 9.8 13.7 23.5 14.8 11.1 15.3 18.7 19.5 15.4 12.5 26.2 15.4 15.6 5.8 15.4 13.4 24.6 14.0 25.7 24.6 30.8 14.4 18.6 14.1 17.9 13.3 15.7 33.0 17.8 17.2 18.6 15.3 11.5 26.1 21.0 16.5 9.4 25.9 11.3 7.5 18.8 32.6 0.7 0.5 2.5 1.9 1.0 1.3 0.4 9.7 6.1 40.8 6.4 6.6 13.4 11.2 8.7 11.1 8.6 7.4 5.1 4.9 2.1 9.8 5.9 5.3 15.3 7.7 13.2 2.4 6.3 3.5 4.3 11.9 17.3 1.5 5.8 11.9 7.7 11.2 12.1 7.4 4.5 4.0 11.5 5.3 3.4 2.3 12.3 9.3 3.7 13.3 1.6 11.4 37.8 7.3 8.3 5.1 8.2 22.6 5.5 2.2 6.0 6.7 8.0 6.0 4.7 6.1 3.4 0.7 8.3 2.5 7.8 2.5 0.7 0.0 1.2 1.1 0.1 0.1 1.2 0.9 0.1 0.7 1.1 1.3 0.0 1.0 1.9 0.5 0.6 0.4 17.6 17.6 37.1 19.6 15.4 12.5 15.4 13.4 14.4 16.5 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavourable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 18.8 14.3 30.7 14.6 29.1 52.3 38.6 24.0 19.8 21.5 17.8 23.7 25.1 27.5 20.9 35.9 7.8 9.7 21.1 21.5 36.8 6.6 20.6 10.8 61.8 24.6 9.8 0.9 46.9 9.7 53.0 23.7 55.8 13.3 0.0 56.4 10.3 22.7 6.1 15.6 22.8 27.5 21.0 0.1 14.3 6.6 12.0 20.0 16.5 0.0 17.9 3.9 17.8 70.1 42.7 18.3 12.3 28.5 0.0 0.0 16.7 27.5 12.5 31.2 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21754500-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.3" "Cell line enhanced" "Detected in all" "K-562: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069" Approved 250000 "CAB004229: AB_627547, HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 16.1 21.1 32.9 18.3 80.3 20.2 13.6 31.0 54.5 18.6 18.5 23.2 9.6 13.7 17.4 10.6 25.7 16.9 14.9 22.8 32.4 23.4 21.7 16.4 19.9 16.6 18.4 23.6 16.0 19.8 27.4 10.9 17.2 27.6 16.4 19.9 14.2 15.8 17.8 28.2 17.5 15.1 22.8 20.4 19.8 17.2 24.2 21.5 19.5 23.0 11.1 21.4 17.7 15.3 2.5 3.2 13.5 4.9 7.0 13.7 2.5 19.3 12.2 15.7 9.0 18.7 18.9 6.0 21.4 20.0 19.2 18.6 9.7 10.3 10.7 10.6 28.6 18.4 18.5 17.1 25.1 43.1 17.3 19.4 11.5 11.4 15.4 27.3 20.1 14.0 13.7 23.2 21.5 26.2 79.5 12.2 23.4 7.9 17.6 6.0 5.9 12.1 19.4 39.0 2.9 11.0 15.9 12.9 7.1 23.1 14.0 12.5 10.5 9.2 22.9 16.1 21.0 18.4 13.6 11.7 14.3 16.7 15.2 13.3 17.4 1.0 4.0 5.8 13.7 4.6 3.9 2.0 2.9 4.9 3.2 2.5 2.8 5.1 13.5 7.0 4.9 3.2 2.7 2.5 32.9 80.3 31.0 54.5 32.4 23.4 18.4 23.6 27.6 21.5 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.3" "Cell line enriched" "Detected in many" 6 "AF22: 58.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favourable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favourable (5.57e-4)" 17.2 11.9 31.6 3.7 34.5 9.7 6.2 26.1 58.3 11.4 4.0 12.6 8.1 3.2 11.0 14.2 7.4 11.9 10.4 5.1 36.0 28.6 15.0 2.7 6.5 3.9 31.5 36.4 11.3 5.6 10.9 31.5 3.4 37.9 16.6 4.3 5.4 3.4 18.9 2.0 3.5 3.9 11.4 23.1 5.3 4.3 18.2 15.8 0.0 15.3 0.4 3.6 11.1 10.2 3.7 3.0 6.9 1.8 3.3 3.6 2.3 1.0 1.9 58.9 1.8 1.6 1.3 2.2 1.2 1.1 1.0 0.4 1.1 1.7 2.6 2.0 0.7 3.6 0.6 1.5 1.7 3.7 1.6 2.1 2.3 1.9 1.4 0.9 1.2 1.6 0.7 1.4 1.9 1.2 1.9 9.7 0.6 1.5 1.7 1.1 3.4 1.2 1.8 1.5 0.9 4.2 6.2 3.6 3.2 1.2 4.8 0.8 3.5 1.2 2.7 2.6 2.6 1.1 1.0 3.2 1.9 1.6 3.7 1.3 1.4 6.9 1.8 3.3 2.3 1.6 2.4 3.7 1.9 2.5 1.6 3.3 2.7 3.6 6.2 3.3 1.5 3.0 2.7 2.3 31.6 34.5 26.1 58.3 36.0 28.6 31.5 36.4 37.9 15.8 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria Mitochondria "CAB012961: AB_2533144, HPA045069: " "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavourable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 20.4 5.7 14.2 7.5 17.3 0.8 8.2 22.0 23.7 6.6 2.7 2.8 1.0 1.9 8.2 6.2 5.3 7.0 8.8 8.8 11.7 9.1 5.0 1.5 8.5 8.5 7.2 19.9 5.3 3.1 6.4 10.9 8.4 6.6 7.2 2.7 4.1 5.7 8.0 5.0 6.4 2.6 9.8 5.5 7.3 4.6 3.1 4.1 0.9 4.5 5.3 6.1 6.0 4.4 1.1 0.0 0.0 0.3 0.0 0.9 0.0 1.7 4.2 4.6 17.3 6.1 9.2 0.1 6.4 4.6 4.3 1.7 1.6 3.2 0.0 5.8 6.0 4.2 3.0 2.6 0.3 8.9 2.1 6.1 5.5 0.4 7.0 1.5 9.5 12.8 7.6 1.2 0.5 9.4 4.9 16.7 4.2 7.4 0.3 5.6 0.4 4.8 16.7 0.1 5.9 6.5 0.0 4.3 11.5 5.5 2.3 4.6 7.6 4.8 14.7 12.9 10.8 0.9 2.4 0.7 1.9 7.1 6.5 1.7 10.8 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.4 0.2 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 14.2 17.3 22.0 23.7 11.7 9.1 7.2 19.9 6.6 4.1 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261825 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 104.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31 "NK-cell: 3.0" "Lineage enriched" "Detected in single" 31 "NK-cells: 3.0" "Region enhanced" "Detected in many" "cerebellum: 35.4" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: " "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 3.0 1.6 4.5 2.1 4.5 1.0 1.8 9.0 7.0 2.1 1.4 2.1 1.6 2.0 5.4 5.1 3.3 2.9 2.4 5.1 3.9 3.6 2.5 1.0 2.1 2.0 3.5 5.7 3.0 1.4 1.2 7.0 2.3 2.6 2.9 1.1 2.2 1.4 3.7 104.2 0.9 1.5 4.2 2.6 1.6 1.5 1.6 2.4 0.0 1.3 10.8 1.1 2.4 1.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 10.3 6.4 2.4 7.4 5.6 6.2 3.5 7.9 6.9 13.3 8.5 9.2 3.2 19.4 10.8 8.7 6.9 11.0 1.6 2.5 5.6 15.4 12.7 19.3 11.4 17.9 11.9 25.2 13.4 2.9 3.0 0.0 15.0 11.2 18.1 6.1 5.7 0.0 15.9 7.5 10.4 18.1 6.7 19.7 7.9 1.4 8.5 2.9 6.1 0.2 9.8 3.3 13.8 7.8 13.7 12.4 2.9 4.9 4.2 3.2 10.4 3.5 11.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 4.5 4.5 9.0 7.0 3.9 3.6 3.5 5.7 2.6 2.4 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 45.7;RPMI-8226: 27.6;RT4: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 16.5;T-cells: 27.8" "Region enhanced" "Detected in some" "cerebellum: 6.5" "Region enriched" "Detected in some" 15 "cerebellum: 59.9" "HPA007667, CAB025854" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favourable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 6.5 22.0 2.2 5.4 4.0 2.9 6.8 2.8 7.3 6.8 18.9 0.5 36.8 18.8 1.9 10.3 41.1 2.4 12.0 1.2 1.7 1.8 6.5 2.8 9.6 11.2 0.8 3.8 3.9 24.6 18.8 12.4 10.5 2.5 6.8 16.0 2.4 20.7 26.3 0.9 28.6 37.7 2.1 0.8 5.9 12.2 23.7 1.1 5.0 13.8 16.0 18.5 7.3 13.9 16.5 0.1 5.2 0.3 2.8 27.8 6.7 19.3 0.1 0.3 0.2 1.1 5.6 2.7 1.5 0.2 0.2 0.5 16.2 19.1 4.6 1.2 1.5 15.1 0.0 45.7 0.4 11.8 5.1 0.1 0.5 16.0 1.9 0.1 1.2 4.8 16.2 2.9 0.6 3.0 0.3 5.2 0.5 10.2 0.1 1.2 0.1 0.3 11.4 0.2 27.6 8.8 28.6 19.3 0.3 1.7 0.3 0.1 21.7 2.5 4.0 1.4 0.2 0.5 0.3 0.3 6.9 1.4 0.0 0.5 0.1 5.2 0.3 4.5 16.2 0.0 10.5 10.8 11.6 13.0 0.1 16.5 10.6 11.9 3.9 2.8 0.0 0.0 27.8 6.7 2.2 4.0 2.8 7.3 1.7 1.8 0.8 3.8 2.5 1.1 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 32.1;neutrophil: 12.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" 7100000 "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 21.5 20.6 11.7 18.4 15.5 49.9 20.7 26.5 18.1 22.0 20.5 12.5 11.9 16.9 38.8 12.1 24.0 18.9 16.0 16.4 9.3 9.5 16.0 29.8 21.5 29.0 12.0 11.3 17.7 18.5 15.0 27.2 27.3 10.2 23.4 18.3 17.0 16.7 16.5 21.2 25.6 22.5 26.0 10.6 35.5 18.2 11.1 10.3 34.1 20.9 17.6 20.8 25.0 30.0 2.3 4.0 32.1 4.9 3.0 2.8 2.1 18.3 10.1 10.9 17.5 24.8 24.8 24.0 19.2 25.0 22.8 23.8 24.7 9.5 14.9 19.1 21.1 13.2 18.0 16.6 23.9 16.8 14.3 34.4 14.4 20.6 13.7 21.6 20.8 17.4 16.2 16.4 16.3 25.8 19.0 18.7 15.5 8.7 22.2 26.0 6.7 10.1 26.4 17.7 13.8 16.1 25.3 8.2 7.0 17.3 13.0 20.1 15.3 40.4 18.1 20.5 11.9 12.9 17.6 9.2 21.0 14.9 9.3 42.8 16.8 32.1 4.9 3.0 2.4 3.5 2.8 1.5 2.2 2.6 4.0 2.3 2.5 2.4 12.3 3.0 4.7 1.9 2.6 2.1 11.7 15.5 26.5 18.1 9.3 9.5 12.0 11.3 10.2 10.3 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716259-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9;epididymis: 27.6;fallopian tube: 29.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.1;HeLa: 14.0;MCF7: 13.6;T-47d: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 0.6 0.1 3.6 0.3 8.1 0.1 1.1 0.2 2.1 4.5 0.4 8.7 5.2 0.5 2.2 27.6 1.3 29.5 0.4 1.1 5.4 4.6 3.9 0.2 7.4 0.5 0.2 1.5 4.7 2.0 9.1 4.2 0.6 26.9 0.9 0.4 1.6 3.0 2.4 0.2 4.9 0.7 0.5 0.4 0.5 0.9 7.3 2.4 0.1 8.4 0.5 0.4 0.5 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.7 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 7.1 0.0 1.3 0.0 5.3 0.0 0.2 0.0 1.1 1.6 0.0 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 13.6 0.0 0.0 2.0 1.1 0.0 2.9 0.3 0.9 1.3 3.9 3.9 0.0 2.8 0.0 12.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 8.1 0.2 2.1 5.4 4.6 0.2 1.5 26.9 2.4 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 25.1;neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Approved Nucleoplasm Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavourable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 24.9 18.5 63.3 15.3 43.2 15.6 21.1 24.8 52.0 21.3 45.1 30.4 6.3 39.7 24.2 11.4 44.1 28.7 25.6 21.2 37.1 34.0 13.4 8.8 23.3 13.1 33.8 27.4 32.7 13.0 26.1 15.2 27.6 27.6 20.1 36.7 26.2 17.1 18.3 13.9 18.7 49.2 24.0 27.8 15.9 33.7 11.6 19.5 8.4 20.5 18.7 26.0 18.2 22.2 1.4 1.5 25.1 2.7 0.8 3.1 1.4 13.7 7.5 16.1 9.1 40.5 53.8 9.0 10.3 25.6 16.4 19.6 9.0 27.8 13.9 10.2 28.8 5.1 13.5 12.1 16.0 26.3 15.7 4.3 8.3 15.0 40.7 3.1 11.9 33.1 7.0 18.7 8.4 41.6 5.8 17.9 21.6 36.3 14.3 5.0 4.3 6.6 17.0 9.6 31.2 14.9 8.7 14.2 10.1 5.9 20.8 6.0 13.6 7.6 29.4 10.8 9.3 12.3 3.5 20.3 9.3 7.1 21.6 6.7 7.6 2.4 2.7 25.1 0.9 1.9 1.4 1.3 2.1 1.6 1.4 1.4 1.5 1.6 11.3 0.8 1.0 1.5 3.1 1.4 63.3 43.2 24.8 52.0 37.1 34.0 33.8 27.4 27.6 19.5 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560078-50731824 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.4;brain: 33.4;parathyroid gland: 43.5" "Cell line enhanced" "Detected in some" "HAP1: 3.0;HeLa: 4.4;NTERA-2: 3.0;SCLC-21H: 15.4;SH-SY5Y: 3.7" "Group enriched" "Detected in many" 5 "glioma: 15.2;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 1.9 26.4 16.9 1.1 33.4 0.9 1.8 15.9 23.9 1.4 2.6 9.5 3.8 1.6 1.8 4.5 3.5 1.5 3.0 16.9 13.0 14.3 4.5 7.0 3.5 0.9 17.1 9.1 4.2 2.5 43.5 8.3 3.7 20.5 5.3 1.8 4.1 1.8 12.4 1.7 1.0 1.9 5.2 11.8 1.1 1.3 3.5 12.4 1.7 7.8 0.0 0.9 2.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.5 1.4 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.1 15.4 3.7 0.0 1.1 2.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 33.4 15.9 14.5 13.0 14.3 17.1 9.1 20.5 12.4 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067372 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262" Approved Supported Enhanced Cytosol Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868" "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 11.8 7.4 14.4 10.9 23.2 25.6 13.7 33.0 24.5 16.3 18.7 12.5 9.3 16.3 15.9 13.3 32.3 8.2 17.0 9.1 13.3 15.9 14.4 32.6 12.6 9.4 13.1 16.8 11.5 8.5 12.2 15.3 13.9 23.8 10.5 18.1 9.5 17.9 11.4 27.1 24.0 26.2 17.8 14.2 9.2 15.7 25.7 13.0 11.7 13.4 22.7 12.4 18.9 22.4 4.9 4.2 3.0 4.5 6.5 7.9 3.6 8.7 11.8 23.3 8.9 7.2 11.9 17.0 12.5 12.6 11.6 13.7 14.1 5.3 12.6 8.8 16.0 12.4 17.9 23.9 15.9 7.7 5.6 18.8 7.0 22.3 17.4 14.0 40.2 12.7 43.9 14.0 36.4 10.9 24.3 21.5 14.7 19.7 9.8 11.0 8.2 5.7 8.6 15.0 20.2 11.1 36.9 11.4 10.8 10.1 8.2 18.3 7.5 20.9 10.8 13.9 15.0 9.0 16.7 11.2 32.9 15.6 17.2 20.6 17.0 3.0 4.5 1.2 3.8 4.3 4.7 4.9 5.6 4.3 4.2 2.6 5.4 3.8 0.6 6.5 2.8 1.9 7.9 3.6 14.4 23.2 33.0 24.3 13.3 15.9 13.1 16.8 23.8 13.0 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: " "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.5 15.0 6.4 7.3 7.6 9.2 11.8 12.5 7.9 13.4 15.3 7.2 6.0 9.2 13.1 14.1 17.3 9.4 11.8 8.2 5.9 4.7 10.8 4.8 9.9 9.2 8.2 5.2 25.4 5.7 7.3 7.5 12.5 6.7 14.0 6.9 10.5 7.8 12.3 7.5 13.1 11.2 13.8 7.1 13.2 8.0 13.3 7.5 4.5 8.6 11.3 10.6 12.7 15.9 2.2 2.6 11.5 7.4 5.5 4.7 3.0 4.1 6.5 5.4 4.2 27.1 11.3 6.3 5.6 5.2 7.8 7.2 7.5 0.7 2.5 4.6 9.7 4.6 6.3 5.1 4.9 4.3 4.8 1.2 4.7 3.3 11.7 1.1 4.2 11.9 3.6 11.8 4.2 5.7 2.2 0.9 7.7 2.7 8.3 4.4 6.2 4.3 4.5 7.9 1.7 2.6 2.3 2.4 7.2 5.7 0.5 2.9 3.5 1.4 3.2 8.4 6.2 9.2 3.8 1.6 2.4 0.6 9.7 1.0 5.0 1.0 3.6 11.5 4.7 7.4 2.5 2.2 2.2 4.1 2.6 1.4 2.1 2.6 1.3 5.5 6.5 1.7 1.0 3.0 6.4 7.6 12.5 7.9 5.9 4.7 8.2 5.2 6.7 7.5 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favourable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 13.4 11.7 15.3 11.5 18.5 13.3 22.1 33.6 35.2 15.2 13.9 12.9 19.5 16.7 17.1 10.8 16.1 12.4 15.1 11.2 20.0 18.0 20.1 23.6 11.7 12.0 15.9 16.7 18.9 15.3 12.7 23.7 12.2 23.6 13.0 14.3 12.4 17.2 15.9 18.9 10.8 17.7 14.6 13.7 9.6 12.2 23.4 12.2 20.5 22.3 9.0 13.8 11.8 13.0 4.5 4.3 5.2 4.3 4.7 5.7 3.5 15.7 4.3 14.3 8.1 5.5 6.5 11.1 23.8 16.3 14.3 11.7 4.9 16.4 5.7 6.5 13.3 9.7 5.0 9.2 18.7 34.1 8.2 8.2 5.0 6.7 9.1 14.0 9.6 5.5 10.6 10.6 21.1 13.1 13.1 10.6 9.3 4.6 17.1 7.4 8.9 3.1 11.2 14.7 5.7 8.7 6.1 24.1 19.1 9.3 7.8 10.7 8.5 6.7 11.2 10.7 25.6 8.1 17.9 3.3 8.1 11.6 7.4 14.9 6.1 0.0 3.3 3.0 4.1 2.8 4.7 4.5 5.7 5.0 3.3 2.9 5.6 3.9 5.2 4.7 4.3 4.3 2.9 3.5 15.3 18.5 33.6 35.2 20.0 18.0 15.9 16.7 23.6 12.2 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell line enhanced" "Detected in all" "HDLM-2: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "basophil: 13.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008910 Approved "CAB008910: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favourable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 10.3 12.4 22.9 9.6 31.8 10.3 11.4 48.7 41.4 10.8 12.4 10.6 4.7 10.1 8.7 9.5 8.7 8.8 7.8 14.0 24.3 25.0 12.2 9.7 10.8 10.0 22.0 21.0 8.5 25.9 16.3 8.8 10.9 29.4 11.7 15.3 7.0 9.9 13.1 20.5 6.3 10.4 11.4 16.8 8.6 12.3 9.4 10.3 7.1 15.4 5.1 11.3 9.9 7.3 1.4 1.4 13.2 2.4 1.3 3.1 0.3 17.0 14.1 12.5 15.6 12.4 13.9 26.9 16.4 14.6 13.9 13.9 18.5 12.2 18.3 28.4 17.4 13.1 12.8 27.6 16.3 68.7 12.4 7.6 15.7 13.1 9.4 15.7 13.3 10.2 12.4 13.4 13.0 16.4 8.4 13.3 18.8 22.4 15.6 6.6 8.7 8.4 15.2 21.3 8.7 10.5 16.4 14.4 10.2 19.3 18.8 13.1 19.1 13.7 11.7 16.6 16.8 23.4 24.5 9.6 11.3 12.5 17.6 14.7 11.0 13.2 0.6 2.5 2.0 1.3 2.0 1.0 1.5 1.8 1.0 1.4 1.0 1.2 0.9 1.3 2.4 1.4 3.1 0.3 22.9 31.8 48.7 41.4 24.3 25.0 22.0 21.0 29.4 10.3 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: , HPA063708: , HPA064435: " "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 20.9 8.3 11.5 12.9 34.0 20.0 14.3 14.6 33.1 22.3 21.1 15.8 10.2 10.1 10.2 29.4 15.9 8.6 15.5 16.1 11.7 6.5 16.9 10.3 10.2 26.3 24.9 56.6 27.5 19.9 21.4 23.7 18.2 19.4 45.9 18.0 26.0 10.0 18.0 13.3 11.6 25.8 24.1 3.2 16.8 12.8 9.2 11.9 17.2 29.1 20.2 14.1 24.2 17.3 20.1 17.0 23.3 19.8 59.8 53.1 8.2 22.8 15.2 6.6 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm Nucleoplasm "HPA058275: " "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favourable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favourable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.0 7.1 3.0 8.5 4.6 11.5 6.7 5.6 8.0 8.7 7.4 11.1 21.5 9.3 5.7 18.7 8.2 20.5 22.1 7.8 20.4 4.9 48.7 10.2 10.1 9.1 35.0 25.9 9.1 13.8 20.2 27.5 7.6 13.6 6.1 18.2 9.4 14.9 35.3 11.2 29.5 6.6 7.2 13.9 40.3 13.2 5.6 4.0 5.0 14.2 6.4 8.9 21.7 5.5 6.8 15.7 35.3 13.8 4.1 7.6 7.7 36.4 55.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavourable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 15.1 20.2 19.5 16.4 14.1 14.3 29.7 15.2 18.4 23.4 16.2 26.0 12.5 22.9 11.3 17.9 15.2 25.6 15.9 22.0 15.2 14.0 20.4 14.0 20.8 17.1 25.6 14.5 15.1 22.9 22.3 26.6 17.1 28.1 9.1 17.0 17.0 25.4 40.5 27.7 14.2 25.2 14.2 22.0 18.6 22.0 24.1 20.4 17.3 29.5 21.1 23.8 29.3 14.9 13.3 13.4 13.6 19.0 18.6 22.7 27.1 16.2 18.7 18.8 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 MARCH1 "FLJ20668, MARCH-I, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4;lymphoid tissue: 32.4" "Cell line enhanced" "Detected in many" "Daudi: 9.4;U-266/70: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 95 "classical monocyte: 16.8;eosinophil: 9.9;intermediate monocyte: 17.0;memory B-cell: 18.5;myeloid DC: 18.1;naive B-cell: 15.7;non-classical monocyte: 17.2;plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014600 Uncertain Supported Mitochondria Mitochondria "HPA014600: AB_1853573" "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 7.7 4.2 11.6 20.5 19.7 3.9 4.0 3.1 14.5 3.7 3.9 8.5 0.1 4.4 3.9 4.6 3.6 4.2 5.9 2.6 12.6 10.1 3.0 4.5 8.3 28.5 17.3 6.3 4.2 4.1 1.5 4.1 10.2 13.5 3.5 5.1 2.4 4.6 1.8 1.6 4.9 9.0 6.5 24.4 32.4 4.1 2.3 17.9 2.6 3.2 1.4 24.6 9.0 4.2 18.5 18.1 9.9 17.2 0.1 0.0 6.6 0.8 0.7 2.9 1.7 0.0 0.0 1.8 1.2 0.1 0.0 0.0 1.6 3.3 9.4 3.5 0.0 1.4 0.0 0.0 0.0 1.0 1.0 6.7 3.7 0.6 0.0 4.1 2.2 0.0 0.0 0.0 0.2 0.0 2.5 4.9 3.3 1.0 2.3 2.6 3.6 1.3 2.6 0.5 0.7 0.1 1.5 1.5 1.3 0.9 1.4 0.5 4.0 0.7 3.1 1.1 2.0 0.7 2.3 9.7 3.2 2.6 1.3 2.1 1.5 0.0 16.8 9.9 0.0 17.0 0.0 18.5 0.0 0.0 18.1 15.7 0.0 0.0 0.1 0.1 17.2 6.8 0.0 6.6 11.6 19.7 3.1 12.5 12.6 10.1 17.3 6.3 13.5 17.9 MARCH10 "FLJ35757, MARCH-X, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 80.2" "Cell line enhanced" "Detected in some" "BEWO: 3.8;EFO-21: 7.2;HSkMC: 3.2;SCLC-21H: 12.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.2 0.1 0.7 0.2 1.6 0.0 0.1 0.1 0.3 0.5 0.1 1.9 0.6 0.0 0.3 4.8 0.1 7.9 0.1 0.1 1.0 1.0 0.6 0.1 1.4 0.1 0.2 0.5 1.0 0.1 0.3 4.5 0.1 1.8 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 80.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.0 0.6 3.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 3.8 1.6 0.2 1.2 0.3 0.0 0.1 0.0 7.2 0.5 0.0 0.0 0.4 1.3 0.0 0.0 1.2 0.7 0.0 1.5 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.4 0.1 0.1 0.3 0.2 0.0 0.0 0.2 1.1 0.0 12.4 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.7 0.3 0.7 0.1 0.6 1.8 0.0 0.6 0.0 0.0 0.7 0.3 0.7 1.6 0.1 0.3 1.0 1.0 0.2 0.5 1.8 0.3 MARCH11 "MARCH-XI, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 42.1" "Cell line enriched" "Detected in some" 14 "SH-SY5Y: 43.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (9.91e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" 0.4 1.1 1.8 0.3 3.4 0.3 0.4 3.7 3.7 0.3 0.4 0.0 0.0 0.3 0.4 0.3 0.3 0.3 0.3 2.2 2.0 3.2 0.5 0.5 0.4 0.3 1.5 2.0 0.5 1.0 0.3 6.8 0.4 2.1 0.6 0.4 0.6 1.4 0.3 0.3 0.3 0.4 0.3 0.5 0.3 0.4 42.1 0.0 0.0 0.3 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.4 3.7 3.7 2.0 3.2 1.5 2.0 2.1 0.0 MARCH2 "HSPC240, MARCH-II, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavourable (6.48e-4)" "prognostic favourable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favourable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favourable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 37.7 12.4 30.7 13.5 28.3 17.5 23.9 8.6 39.1 9.8 29.8 20.7 9.7 11.2 12.5 39.0 19.3 10.0 11.4 38.9 23.5 21.9 11.0 17.9 18.2 15.0 30.8 19.8 8.2 10.0 10.5 11.3 13.9 20.2 16.0 10.3 12.7 13.4 21.8 46.9 12.7 11.7 28.5 27.8 18.9 13.3 8.6 13.3 8.4 21.3 14.1 10.0 20.4 9.7 3.6 26.5 20.4 14.6 3.7 7.3 10.1 5.4 7.0 3.2 14.7 19.5 6.4 5.4 6.0 7.3 4.8 5.0 3.4 2.6 2.2 17.6 12.8 3.9 4.1 8.4 3.7 10.9 9.7 16.7 3.3 7.6 10.5 2.4 25.1 7.6 9.7 4.6 4.1 18.7 2.3 12.3 3.7 10.5 3.3 7.9 6.6 17.0 5.3 1.0 5.5 11.0 6.5 1.6 8.9 0.4 6.4 11.3 4.9 5.2 18.8 6.7 4.1 22.3 5.0 11.0 13.0 2.5 10.9 5.0 5.1 20.4 10.0 15.4 5.7 14.6 5.9 3.6 5.9 4.6 6.7 3.5 4.0 5.4 12.5 3.7 12.8 26.5 7.3 10.1 30.7 28.3 8.6 39.1 23.5 21.9 30.8 19.8 20.2 13.3 MARCH3 "MARCH-III, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030808 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 24.6;HUVEC TERT2: 16.4;TIME: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 8.8;naive B-cell: 13.1" "Lineage enriched" "Detected in many" 5 "B-cells: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043406 Uncertain Supported Vesicles Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 11.3 6.0 5.6 11.0 9.4 6.6 6.2 5.3 4.8 2.0 10.8 8.2 0.5 2.4 3.7 3.6 3.4 3.2 10.4 15.2 7.8 6.8 2.0 1.9 5.2 5.2 9.5 2.3 4.0 5.0 1.7 10.8 4.0 12.3 2.9 11.8 9.7 11.2 1.1 11.9 11.5 5.2 6.5 16.0 3.7 5.5 14.2 7.6 2.1 3.6 3.4 5.8 6.5 6.7 13.1 0.7 2.5 0.4 1.9 2.6 0.7 0.3 1.2 2.3 1.2 2.1 2.0 0.7 8.4 3.5 6.8 10.0 1.1 0.5 2.2 0.8 1.3 0.7 2.9 1.5 9.6 0.5 2.7 7.0 1.9 1.1 3.4 2.8 1.8 1.4 0.5 24.6 2.9 16.4 2.9 0.4 5.5 0.8 0.3 1.2 2.0 2.8 0.9 9.4 0.6 0.5 1.2 0.7 0.5 1.9 0.3 1.0 1.7 2.9 19.9 1.3 1.0 7.7 0.9 1.1 1.3 1.3 5.0 2.3 1.1 0.0 0.2 2.5 0.5 0.4 0.1 8.8 0.6 0.3 0.1 13.1 2.4 0.5 0.8 1.9 0.3 0.7 2.6 0.7 5.6 9.4 5.3 4.8 7.8 6.8 9.5 2.3 12.3 7.6 MARCH4 "KIAA1399, MARCH-IV, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372027 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 16.6;pituitary gland: 13.1" "Cell line enhanced" "Detected in many" "BJ: 33.3;fHDF/TERT166: 21.2;TIME: 15.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014348 Approved "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.7 2.9 7.0 0.7 11.9 0.7 0.6 1.0 16.6 0.6 1.1 0.3 0.0 1.5 0.7 0.7 0.6 2.5 0.6 0.6 5.8 5.6 0.6 0.6 0.8 0.6 2.0 4.8 0.6 1.5 0.6 13.1 3.1 3.4 0.7 1.2 0.1 0.6 0.6 0.6 0.7 1.4 0.6 1.6 0.6 5.1 0.7 1.1 0.0 0.6 0.0 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.5 1.2 0.0 0.0 0.1 0.8 0.0 33.3 11.4 7.2 2.5 0.0 0.5 0.0 5.2 21.2 0.0 0.0 13.1 7.1 0.0 0.0 2.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.5 9.9 9.3 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.9 0.0 0.0 0.0 0.0 0.0 15.6 11.2 11.6 0.0 8.9 0.0 0.0 0.0 2.5 0.0 7.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.0 11.9 1.0 16.6 5.8 5.6 2.0 4.8 3.4 1.1 MARCH5 "FLJ20445, MARCH-V, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291163-92353964 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria Mitochondria "HPA056596: " "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" 18.2 21.7 17.5 17.7 18.3 20.7 27.1 16.8 25.7 15.5 15.4 12.7 20.7 15.8 19.3 18.8 28.0 14.8 15.4 18.4 15.8 15.1 21.7 27.6 16.5 16.6 16.3 17.9 20.9 16.7 16.3 12.3 16.3 14.8 22.2 14.8 14.5 19.4 19.3 42.6 13.7 16.0 18.1 14.0 12.1 14.4 20.1 13.5 25.0 24.5 21.5 17.3 14.7 21.0 7.3 9.4 16.8 10.2 6.5 8.7 6.6 16.4 8.9 17.6 20.2 12.1 12.6 9.1 14.7 16.2 18.4 18.9 5.9 11.8 9.6 10.2 14.4 13.6 12.3 12.3 26.5 7.2 14.5 7.7 8.4 13.9 14.6 12.3 7.7 12.8 16.7 12.1 25.5 16.1 8.4 12.0 14.7 10.4 10.8 14.1 4.1 13.5 11.8 18.1 5.7 18.8 10.7 8.2 15.2 12.8 9.5 15.6 16.5 9.6 15.6 8.6 9.5 9.4 20.1 12.2 9.3 8.5 7.9 17.0 5.7 5.2 8.3 9.0 7.6 10.2 7.6 7.3 8.4 8.0 9.4 6.7 8.7 8.3 16.8 6.5 8.5 6.2 7.8 6.6 17.5 18.3 16.8 25.7 15.8 15.1 16.3 17.9 14.8 13.5 MARCH6 "MARCH-VI, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353703-10440388 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA040841: , HPA063246: " "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" 22.5 25.6 28.6 21.2 25.5 57.0 62.4 42.0 53.8 21.4 23.0 24.0 18.3 28.6 24.7 24.2 22.8 25.1 22.0 35.5 27.6 23.7 31.9 28.9 35.0 33.2 29.8 39.1 34.0 41.5 56.0 27.4 20.3 33.4 21.4 18.4 20.3 28.0 23.4 49.8 23.9 32.1 27.4 38.6 31.2 26.0 25.6 26.9 18.0 26.8 17.1 20.3 24.6 36.4 13.4 7.3 15.6 12.1 9.9 15.7 9.4 12.4 18.7 31.4 24.3 18.0 14.5 25.7 19.7 18.4 17.0 21.8 17.8 33.3 13.1 30.1 18.4 17.3 16.6 12.8 23.1 27.7 15.1 17.1 62.2 12.1 12.7 20.2 19.2 16.9 14.2 17.1 18.7 15.8 20.4 29.6 15.5 14.2 10.9 15.6 11.4 13.2 17.0 13.1 18.9 13.3 24.2 13.5 19.6 36.7 20.1 12.9 16.7 11.0 15.2 20.7 20.2 10.2 14.7 20.8 29.8 18.7 15.2 14.1 14.7 15.6 8.5 13.6 13.5 9.6 15.4 13.4 13.4 13.4 7.3 11.5 15.7 14.6 13.7 9.9 12.1 5.6 11.7 9.4 28.6 25.5 42.0 53.8 27.6 23.7 29.8 39.1 33.4 26.9 MARCH7 "AXOT, MARCH-VII, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavourable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 31.6 21.1 18.3 27.4 29.0 22.6 28.9 33.1 23.0 33.4 25.3 17.0 22.0 17.1 32.3 24.1 47.6 22.7 22.4 28.1 16.9 14.4 21.8 30.9 29.5 32.9 21.6 17.8 31.6 15.4 25.3 31.5 41.3 21.5 28.8 22.3 24.8 25.7 22.6 48.0 24.2 25.2 33.8 20.4 28.9 20.0 34.1 21.8 60.4 28.5 25.5 32.9 30.0 35.1 10.0 10.1 46.1 14.5 14.0 14.6 10.5 18.5 12.8 34.5 15.5 25.0 33.1 33.4 31.2 31.6 32.1 29.5 26.4 22.3 26.4 14.2 32.5 23.5 21.2 28.8 41.2 27.0 15.6 35.8 18.6 19.9 24.3 29.3 28.0 29.4 32.9 39.2 34.0 38.5 27.2 25.5 32.4 15.2 18.7 28.1 32.5 18.4 27.9 25.5 21.9 29.5 38.7 20.5 19.3 25.5 18.8 25.0 21.8 35.6 34.7 34.4 20.8 21.1 17.6 20.4 21.4 36.0 21.3 17.8 32.0 24.8 10.3 20.6 11.1 10.6 13.3 10.0 12.1 12.6 10.1 9.7 14.6 14.1 46.1 14.0 14.5 7.9 12.5 10.5 18.3 29.0 33.1 23.0 16.9 14.4 21.6 17.8 21.5 21.8 MARCH8 "c-MIR, CMIR, MARCH-VIII, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favourable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favourable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 10.0 17.6 13.5 11.4 16.0 28.8 12.1 37.5 12.2 10.3 14.6 24.5 8.5 9.7 14.3 8.2 7.5 11.1 9.9 14.1 12.7 11.8 11.0 16.7 10.3 13.5 19.0 9.3 14.2 18.2 15.1 18.1 13.2 14.5 8.8 12.9 12.9 11.5 11.4 9.0 8.9 18.8 12.4 18.2 14.3 9.7 43.2 14.9 10.5 11.5 8.5 13.6 11.0 8.0 5.3 1.7 13.6 1.8 7.3 4.7 2.4 9.1 9.2 7.9 7.0 11.5 14.4 5.9 4.2 19.8 7.8 8.6 2.3 9.5 13.2 7.3 12.3 1.7 8.6 7.2 7.3 20.0 9.5 5.1 4.2 5.5 8.0 6.1 22.7 11.7 9.3 4.0 10.5 12.8 14.3 13.0 6.0 3.2 6.2 3.9 2.6 3.0 7.0 7.9 3.8 5.9 5.3 7.0 9.8 8.3 2.0 7.9 12.2 2.9 8.7 6.2 8.0 9.0 6.6 23.0 18.4 5.8 12.2 8.6 1.6 9.7 1.1 10.0 3.1 1.8 4.7 3.5 3.4 3.3 1.6 5.3 2.7 3.3 13.6 7.3 0.9 1.7 3.1 2.4 13.5 16.0 37.5 12.2 12.7 11.8 19.0 9.3 14.5 14.9 MARCH9 "FLJ36578, RNF179" ENSG00000139266 "Membrane associated ring-CH-type finger 9" Q86YJ5 12 57755098-57760407 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 12 "RH-30: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.96e-2)" "unprognostic (6.78e-2)" "unprognostic (1.90e-3)" "prognostic favourable (3.07e-4)" "unprognostic (2.16e-1)" "unprognostic (6.85e-2)" "unprognostic (8.15e-3)" "prognostic favourable (1.54e-5)" "unprognostic (7.76e-2)" "prognostic favourable (1.59e-4)" "unprognostic (1.08e-2)" "unprognostic (1.06e-1)" "prognostic favourable (2.98e-5)" "unprognostic (2.44e-1)" "unprognostic (2.86e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" 5.9 11.8 11.0 10.7 14.1 6.1 8.8 25.0 16.6 9.5 9.3 7.8 17.5 10.1 6.8 11.9 8.3 9.6 14.3 12.2 10.8 9.9 16.9 5.6 16.5 16.6 7.7 11.0 6.4 14.4 26.3 24.6 10.3 7.4 11.0 9.0 16.8 12.3 17.6 10.5 13.4 12.7 7.0 6.1 19.4 11.6 5.2 6.8 37.6 20.2 6.2 17.8 9.2 7.7 6.8 11.0 2.2 0.7 3.0 6.1 1.3 3.0 1.5 2.4 2.6 0.2 0.0 3.1 0.4 3.2 1.8 1.8 1.9 2.4 7.5 2.5 0.0 2.7 3.9 3.3 1.2 4.4 4.3 0.9 1.1 1.0 2.3 0.9 1.5 0.3 3.5 0.5 1.9 0.8 1.3 7.7 0.4 2.8 4.7 1.1 1.5 3.3 3.9 107.7 8.0 3.6 2.7 5.4 3.6 0.2 0.2 2.0 5.4 1.8 0.0 2.4 1.9 1.3 1.5 8.7 3.9 4.5 2.6 0.2 2.4 2.2 0.5 0.1 4.0 0.7 5.9 5.3 6.0 5.2 1.5 6.8 6.1 4.6 0.2 3.0 0.2 11.0 3.6 1.3 11.0 14.1 25.0 16.6 10.8 9.9 7.7 11.0 7.4 6.8 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 9.4;RT4: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favourable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.8 1.5 2.2 1.5 2.3 0.0 0.0 0.0 0.0 0.0 2.3 9.4 6.1 1.1 0.0 6.9 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.7 2.2 0.0 7.0 0.0 0.0 35.3 6.5 5.8 0.3 0.3 0.4 0.7 0.0 0.0 0.0 3.5 4.8 6.1 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: " "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.4 15.0 12.3 12.9 6.7 8.9 17.1 9.1 8.8 13.2 10.2 16.1 23.7 16.6 16.2 9.5 29.0 11.8 14.3 11.5 11.4 9.3 18.2 11.8 10.4 7.6 19.8 24.1 4.9 19.5 12.1 10.5 10.8 15.5 19.1 8.7 27.6 20.7 14.1 14.0 10.9 17.1 9.1 18.3 9.8 18.6 17.0 11.4 15.8 40.4 10.6 29.4 11.8 10.3 14.0 8.8 18.0 10.1 11.6 12.0 16.2 9.5 10.4 11.1 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.2 16.1 23.5 17.7 28.2 22.1 20.3 23.6 24.9 28.6 27.5 12.6 20.9 15.8 15.0 22.1 25.0 25.6 25.4 36.4 18.4 11.3 20.4 17.1 15.8 53.2 23.3 13.6 25.6 23.6 23.1 47.4 26.4 21.0 37.0 21.4 35.6 15.9 20.7 17.2 24.3 20.9 24.0 12.7 25.3 28.3 20.7 20.6 25.0 17.2 22.9 23.4 20.0 22.8 15.4 10.9 28.6 21.0 24.0 30.4 19.0 18.7 18.7 20.7 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavourable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.8 3.8 15.0 10.9 10.7 17.1 4.2 6.6 10.3 9.8 9.2 2.3 5.1 4.3 5.6 12.0 6.0 10.6 9.6 5.5 7.8 8.7 8.5 4.6 8.2 19.7 2.1 7.4 21.2 13.7 8.2 9.5 13.1 10.8 10.7 10.6 7.4 7.5 6.7 6.4 3.3 29.3 4.9 2.8 9.3 7.2 28.1 12.4 9.7 8.6 5.0 4.1 12.4 10.6 8.8 6.7 6.0 4.2 12.0 9.5 4.8 9.4 4.0 7.0 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874951 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8;SCLC-21H: 26.2;SH-SY5Y: 13.0;U-266/70: 10.7" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "MAIT T-cell: 3.6;T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Approved Vesicles Vesicles "HPA028181: AB_10603872, HPA073106: " "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 1.2 5.2 20.4 1.7 13.6 1.6 1.5 51.0 40.1 1.1 1.5 1.4 0.0 1.7 1.3 1.2 1.3 1.2 1.6 1.3 16.1 16.3 1.2 1.3 1.2 1.3 8.8 19.5 1.5 1.6 1.2 10.4 1.2 19.9 1.2 1.3 1.6 1.3 1.2 1.2 4.1 1.6 1.3 4.2 1.2 1.5 3.9 2.7 0.0 1.2 0.0 1.3 1.2 0.2 0.4 0.0 0.0 0.2 0.0 3.6 0.1 2.2 1.0 0.9 14.8 0.0 0.0 1.2 0.1 0.1 0.2 0.6 0.5 0.9 3.6 1.6 0.0 0.0 4.3 0.0 0.0 2.5 2.9 0.3 3.6 1.6 0.0 0.7 0.7 0.3 0.0 0.5 0.5 0.0 3.1 1.9 0.0 0.5 1.5 0.4 4.4 4.5 9.8 2.9 5.1 0.2 0.1 26.2 13.0 0.5 0.9 2.6 2.4 1.3 0.0 1.8 2.8 2.0 0.4 10.7 8.5 2.1 3.3 2.0 0.1 0.0 0.2 0.0 0.0 0.2 3.6 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 2.0 0.1 20.4 13.6 51.0 34.3 16.1 16.3 8.8 19.5 19.9 2.7 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavourable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 15.2 12.4 12.5 9.6 16.4 23.6 13.9 16.3 11.8 15.1 16.9 14.2 5.0 23.9 7.7 19.9 7.6 15.1 9.3 16.0 11.5 8.1 10.8 14.0 13.0 14.3 5.8 13.9 18.1 12.1 25.3 20.3 14.1 8.3 7.3 18.0 10.4 8.4 6.0 10.3 14.2 12.4 21.0 4.5 7.8 8.3 17.5 10.4 19.2 25.1 8.2 11.4 5.7 13.7 29.3 18.9 15.3 16.1 10.0 8.9 8.7 19.6 7.9 12.1 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favourable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favourable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.6 3.5 20.7 8.3 36.1 12.3 1.8 1.1 72.5 3.8 5.3 19.0 0.2 9.1 3.6 4.9 2.2 4.9 3.1 2.1 19.7 9.3 3.6 6.4 4.6 9.9 13.0 33.6 4.6 14.3 7.1 7.7 2.6 13.0 2.7 4.4 0.7 4.6 4.2 2.6 6.9 8.8 3.0 7.9 11.4 3.9 2.1 12.5 1.8 2.4 0.3 9.4 3.3 2.4 4.4 10.3 23.2 9.7 5.8 8.4 3.1 3.3 4.9 2.3 10.0 6.8 5.5 5.4 3.4 2.2 2.4 3.4 4.9 4.6 8.6 5.1 3.4 1.8 3.3 1.9 1.7 7.3 4.1 3.9 5.2 7.8 5.7 2.1 13.2 6.2 5.7 3.6 1.4 1.0 4.0 5.7 2.7 5.9 4.4 6.9 2.4 6.1 11.9 1.9 6.3 1.8 1.5 3.7 6.1 4.7 2.8 2.0 3.1 4.9 3.9 3.1 3.3 12.9 1.4 6.2 8.3 7.9 6.7 11.1 2.8 0.1 4.5 9.4 8.4 5.6 6.2 4.1 4.7 3.3 2.1 4.4 3.7 6.4 23.2 5.8 9.7 10.3 5.0 3.1 20.7 36.1 1.1 72.5 19.7 9.3 13.0 33.6 13.0 12.5 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 17.5;HDLM-2: 22.2;HEL: 18.4;RT4: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favourable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 16.2 12.9 10.2 6.9 11.8 2.5 12.6 6.2 19.4 13.9 6.9 6.3 6.3 6.3 14.4 8.9 31.2 11.6 9.7 24.5 9.9 8.1 14.2 9.5 13.1 5.0 6.5 9.2 20.2 5.9 35.6 16.7 18.4 11.1 10.1 5.3 5.7 13.7 8.7 12.7 16.9 6.8 11.4 5.6 6.0 8.2 10.7 5.0 37.5 8.1 21.8 20.6 13.6 22.3 3.4 1.1 12.1 0.9 2.4 7.5 1.4 7.4 4.1 2.0 0.1 6.8 6.1 4.9 1.7 2.6 0.6 0.5 3.8 2.0 0.5 3.5 1.4 6.7 6.3 17.5 0.7 22.2 2.0 18.4 2.3 1.6 0.5 0.0 6.5 10.1 9.7 3.8 7.7 13.9 1.7 2.1 4.7 6.5 2.6 0.1 1.3 3.3 0.6 1.8 0.4 1.6 22.5 3.0 2.4 2.2 0.9 0.1 1.5 0.1 13.2 1.6 2.2 2.4 2.8 5.4 2.4 0.1 4.2 0.0 1.3 12.1 0.4 0.8 1.2 0.5 2.9 3.4 4.7 1.2 0.4 2.1 5.0 2.1 4.1 2.4 0.9 1.1 7.5 1.4 10.2 11.8 6.2 19.4 9.9 8.1 6.5 9.2 11.1 5.0 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27186924 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm Nucleoplasm "HPA027175: AB_1853591, HPA054273: " "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavourable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavourable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 9.1 7.0 3.6 8.9 6.1 21.1 8.3 4.0 7.5 7.4 7.6 3.8 5.7 5.7 6.0 6.7 12.3 5.4 5.3 5.6 6.8 4.5 6.5 7.1 10.2 14.8 5.4 5.7 7.0 12.7 6.7 6.3 14.2 6.7 5.5 7.1 5.6 8.0 4.7 4.0 10.1 10.0 6.1 5.6 8.7 6.2 11.3 2.3 21.1 6.5 4.3 12.3 8.7 7.5 3.9 2.6 5.6 4.9 2.3 4.0 1.8 11.7 9.5 18.1 6.7 2.8 4.1 10.7 17.6 7.4 29.2 36.0 11.4 11.8 9.4 6.7 7.4 11.4 11.5 6.9 20.8 8.0 11.1 11.1 6.6 6.6 1.6 4.2 8.4 2.4 3.1 17.6 3.5 6.3 8.4 21.3 17.7 7.8 13.7 4.7 13.4 3.9 8.8 30.2 7.7 7.2 4.4 8.1 11.6 11.1 7.4 7.8 7.5 9.0 5.4 7.3 15.3 18.6 15.4 2.6 4.1 13.9 8.0 12.9 6.0 0.1 4.4 3.8 2.0 4.3 3.0 2.6 2.5 1.8 2.5 3.9 2.5 2.3 5.6 2.3 4.9 2.6 4.0 1.8 3.6 6.1 4.0 7.5 6.8 4.5 5.4 5.7 6.7 2.3 MAT1A "MAT, MATA1, SAMS, SAMS1" ENSG00000151224 "Methionine adenosyltransferase 1A" Q00266 10 80271820-80289684 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 178.8" "Cell line enriched" "Detected in some" 15 "Hep G2: 44.8" "Cancer enriched" "Detected in many" 54 "liver cancer: 209.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048627 Supported 530000 "HPA048627: " "unprognostic (6.92e-2)" "unprognostic (2.63e-1)" "unprognostic (2.88e-2)" "unprognostic (9.43e-2)" "unprognostic (3.79e-2)" "unprognostic (2.49e-2)" "unprognostic (2.03e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.66e-2)" "unprognostic (1.11e-16)" "unprognostic (8.59e-3)" "unprognostic (9.90e-2)" "unprognostic (3.58e-1)" "unprognostic (5.98e-2)" 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 12.5 0.1 0.2 0.2 0.1 0.0 0.0 0.3 178.8 0.1 0.1 0.1 0.0 0.7 9.9 0.0 0.6 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.7 0.0 0.0 0.4 0.2 0.0 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 44.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 MAT2A "MATA2, MATII, SAMS2" ENSG00000168906 "Methionine adenosyltransferase 2A" P31153 2 85539165-85545280 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 205.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009968, HPA043028" Approved Approved Nucleoplasm,Cytosol 950000 Nucleoplasm Cytosol "CAB009968: AB_675710, HPA043028: AB_10960707" "unprognostic (1.38e-3)" "unprognostic (2.58e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (5.29e-5)" "unprognostic (9.89e-3)" "unprognostic (5.90e-3)" "prognostic unfavourable (4.87e-4)" "prognostic favourable (8.94e-4)" "prognostic unfavourable (5.94e-5)" "unprognostic (4.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.59e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-2)" 55.9 68.9 37.4 35.3 54.1 20.4 30.3 37.5 50.0 28.6 35.3 74.5 39.7 33.6 35.8 59.8 33.5 44.9 51.6 35.0 41.7 28.5 52.3 26.4 32.9 27.0 74.8 37.6 44.2 205.8 38.8 60.5 29.3 48.9 40.6 36.8 35.0 28.2 31.3 51.4 33.7 35.8 47.6 57.7 24.7 44.6 34.9 69.4 22.7 94.0 34.1 30.8 46.9 33.4 13.8 15.3 4.9 17.2 16.9 22.8 14.9 29.7 44.2 51.9 32.2 35.7 43.7 30.7 37.4 34.5 39.4 42.1 36.1 100.4 69.8 24.7 45.4 46.4 65.2 55.8 50.7 35.3 47.9 41.7 64.0 31.1 65.3 61.8 46.6 39.5 56.7 42.5 29.7 37.3 46.8 55.0 89.4 25.5 56.3 68.1 34.4 56.9 60.0 49.2 45.2 59.5 47.2 40.9 37.7 33.8 32.7 60.3 27.7 33.2 36.3 48.4 29.2 26.6 44.7 33.9 26.9 50.5 31.6 77.6 25.4 4.8 15.2 4.9 15.4 17.2 22.8 13.8 17.5 16.2 15.3 12.2 16.4 14.3 1.6 16.9 13.7 10.9 15.3 14.9 37.4 54.1 37.5 50.0 41.7 28.5 74.8 37.6 48.9 69.4 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.3;bone marrow: 19.1;brain: 27.4" "Cell line enhanced" "Detected in some" "HL-60: 40.7;HMC-1: 12.5;K-562: 18.1;MCF7: 13.2;NB-4: 28.4;SCLC-21H: 12.4;THP-1: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 19.4;NK-cell: 29.3" "Group enriched" "Detected in many" 54 "NK-cells: 29.3;T-cells: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favourable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 11.2 1.6 22.1 6.8 18.1 19.1 2.2 1.5 27.4 1.5 2.3 1.7 0.0 7.0 1.2 0.4 1.1 4.7 5.1 1.7 25.1 10.0 1.1 2.8 7.3 9.6 7.0 11.0 1.0 1.6 0.1 1.4 1.4 6.1 1.2 1.4 0.6 3.8 1.0 0.8 1.6 6.7 1.1 2.8 14.8 4.1 2.1 1.3 3.5 0.9 0.0 4.5 2.4 0.7 0.4 0.3 0.4 0.0 29.3 19.4 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 4.1 5.4 0.1 0.0 0.0 7.0 4.5 0.5 1.1 0.0 40.7 12.5 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 13.2 0.1 28.4 3.3 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 10.7 1.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 13.2 0.0 2.5 12.2 0.3 0.4 1.2 7.1 0.4 29.3 0.0 0.1 0.1 2.7 22.1 18.1 1.5 27.4 25.1 10.0 7.0 11.0 6.1 1.3 MBOAT1 "dJ434O11.1, LPEAT1, MGC44669, OACT1" ENSG00000172197 "Membrane bound O-acyltransferase domain containing 1" Q6ZNC8 6 20102145-20212399 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 29.9;HEL: 24.5;T-47d: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "unprognostic (1.26e-2)" "unprognostic (4.18e-2)" "unprognostic (2.06e-2)" "unprognostic (5.85e-3)" "unprognostic (3.88e-2)" "unprognostic (5.31e-2)" "unprognostic (2.55e-2)" "unprognostic (6.57e-3)" "unprognostic (1.87e-1)" "unprognostic (1.62e-3)" "prognostic unfavourable (9.15e-4)" "unprognostic (2.90e-2)" "unprognostic (5.59e-2)" "unprognostic (5.17e-2)" "unprognostic (2.56e-1)" "unprognostic (1.70e-1)" "unprognostic (4.24e-2)" 9.9 3.3 1.4 16.5 2.1 6.2 16.5 1.5 1.8 22.5 17.3 6.4 7.1 9.7 18.8 9.9 9.6 18.1 18.8 8.4 1.7 1.7 4.4 4.0 14.0 7.6 6.5 0.7 10.5 4.4 4.7 2.7 3.2 6.2 9.3 15.4 7.2 6.5 9.4 2.2 4.3 21.1 17.2 10.0 4.6 10.6 2.6 3.2 3.9 6.6 6.5 11.1 10.4 12.8 0.3 2.8 6.4 6.8 0.5 4.1 0.9 3.2 3.5 6.5 4.4 0.7 2.2 0.3 5.2 1.4 3.6 4.0 1.9 12.7 0.0 11.0 5.0 29.9 6.3 2.7 5.1 8.2 3.0 24.5 5.6 0.0 4.1 7.8 8.6 0.9 2.4 1.5 6.6 1.9 4.0 4.7 0.8 3.0 4.3 4.6 1.4 1.7 1.5 7.4 17.2 3.7 6.5 0.2 4.1 1.1 5.2 5.6 22.5 2.7 1.8 4.3 2.9 2.4 2.2 6.8 15.1 0.0 0.3 5.4 5.2 6.4 4.4 6.0 0.7 4.7 4.1 0.2 1.2 1.7 2.6 0.3 0.3 0.3 5.7 0.5 6.8 2.8 1.3 0.9 1.4 2.1 1.5 1.8 1.7 1.7 6.5 0.7 6.2 3.2 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003813 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 34.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 6.3;eosinophil: 2.8;neutrophil: 6.7" "Lineage enriched" "Detected in single" 8 "granulocytes: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavourable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavourable (5.32e-4)" 2.3 2.9 12.8 2.9 18.0 24.2 10.1 10.1 20.2 6.0 8.2 16.6 1.2 3.1 5.3 3.5 14.2 3.7 4.3 5.1 14.7 12.4 8.0 1.3 10.9 2.9 23.3 10.3 6.8 2.1 34.7 5.5 3.8 16.2 16.1 9.3 6.4 5.6 4.1 1.2 12.3 4.3 4.6 18.5 2.5 6.9 2.7 17.8 1.9 5.3 16.1 10.3 4.4 7.5 0.0 0.8 6.7 0.7 0.0 0.2 0.3 8.3 2.5 7.8 3.3 3.5 7.9 4.6 4.0 1.4 5.2 3.5 0.7 13.3 2.4 4.8 9.5 6.4 6.9 8.1 7.9 7.4 11.9 10.0 3.7 0.0 4.4 0.0 3.2 5.7 4.8 5.0 3.4 2.7 8.5 1.9 4.5 2.1 2.9 0.2 3.1 9.9 4.4 12.3 0.1 7.7 1.2 4.7 14.3 4.2 25.1 3.9 4.7 2.8 1.5 9.2 4.9 7.1 11.4 0.7 0.2 2.6 14.5 1.4 3.1 6.3 0.7 2.8 0.0 0.2 0.0 0.0 0.2 0.1 0.8 0.0 0.2 0.1 6.7 0.0 0.2 0.1 0.0 0.3 12.8 18.0 10.1 15.8 14.7 12.4 23.3 10.3 16.2 17.8 MBOAT7 "BB1, hMBOA-7, LENG4, LPIAT" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "basophil: 15.7;eosinophil: 30.6;neutrophil: 30.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol Cytosol "HPA055967: " "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavourable (5.55e-6)" "prognostic unfavourable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favourable (4.31e-4)" 10.7 63.1 16.8 14.8 24.2 15.9 7.9 11.3 37.8 10.3 17.7 9.2 15.6 30.3 10.5 8.0 10.5 11.5 14.3 6.9 18.5 23.4 10.5 11.6 11.5 14.7 10.0 18.8 15.1 24.4 23.8 12.4 11.9 21.6 11.4 6.1 8.1 10.8 28.8 7.9 10.0 28.5 6.5 9.2 14.4 16.4 30.8 6.8 7.6 12.7 5.0 6.3 22.6 17.5 0.3 2.9 30.6 2.1 0.9 0.5 0.8 14.0 8.4 1.3 13.8 4.5 3.6 12.2 24.7 8.8 5.7 11.3 4.8 16.0 3.6 11.1 5.3 28.8 0.0 5.0 1.1 5.0 16.4 3.9 9.0 3.1 4.4 8.9 56.5 6.6 3.4 2.8 1.9 10.2 14.5 11.6 2.0 8.5 2.6 3.1 5.8 17.9 8.3 2.4 7.4 5.7 17.0 0.5 3.7 16.5 10.0 5.0 10.2 0.8 20.4 12.1 4.3 3.6 9.7 5.3 9.2 1.5 17.4 6.3 8.0 15.7 2.1 30.6 0.2 1.5 0.5 0.2 0.2 0.2 2.9 0.3 0.1 0.2 30.0 0.9 0.8 0.8 0.2 0.8 16.8 24.2 11.3 37.8 18.5 23.4 10.0 18.8 21.6 6.8 MCAT "fabD, FASN2C, MCT, MCT1, MT, NET62" ENSG00000100294 "Malonyl-CoA-acyl carrier protein transacylase" Q8IVS2 22 43132206-43143394 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003122, HPA035471" Approved Supported Mitochondria Mitochondria "HPA003122: , HPA035471: AB_10670590" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.39e-2)" "prognostic favourable (5.53e-4)" "unprognostic (3.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-3)" "unprognostic (4.71e-2)" "unprognostic (5.13e-2)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" "unprognostic (9.86e-2)" "prognostic favourable (2.18e-4)" "prognostic favourable (3.89e-4)" "unprognostic (3.67e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-1)" 10.4 18.2 13.3 8.2 17.2 11.0 12.8 10.4 24.6 10.6 11.9 9.4 10.7 9.5 11.0 17.2 12.3 20.7 21.4 12.9 14.4 14.2 25.6 24.3 8.6 7.1 12.0 12.0 14.4 16.2 20.3 14.3 9.2 15.1 12.8 10.6 9.9 14.5 10.2 17.7 11.7 9.7 8.6 6.0 7.6 12.1 19.6 5.2 18.4 20.1 14.0 9.9 8.5 8.1 10.2 13.9 2.5 9.5 11.6 10.3 5.6 7.1 9.4 6.7 11.7 5.6 6.0 6.8 8.0 7.1 10.8 10.1 9.4 7.3 12.0 8.3 5.9 12.0 12.6 10.6 8.1 4.1 37.3 4.5 10.8 10.4 9.0 21.3 5.4 4.5 10.3 10.5 8.4 7.7 10.5 4.9 5.2 13.2 9.9 23.2 6.4 16.7 13.2 6.6 19.0 13.5 6.2 8.8 4.7 8.6 16.8 12.1 8.7 13.8 4.6 4.7 9.3 10.2 11.2 8.8 9.0 8.6 10.1 8.1 5.6 0.0 9.5 0.7 7.7 9.1 10.3 8.3 8.6 10.1 13.9 10.2 10.1 7.1 2.5 11.6 5.5 13.7 5.5 5.6 13.3 17.2 10.4 24.6 14.4 14.2 12.0 12.0 15.1 5.2 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808176-68850686 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 93.7;U-698: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303" Supported Supported Nucleoplasm Nucleoplasm "CAB000086: AB_563872, CAB016303: AB_627920" "unprognostic (1.16e-1)" "prognostic favourable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favourable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 16.6 15.3 11.1 12.5 10.8 23.1 12.5 12.0 11.3 13.1 16.6 13.6 11.9 5.2 8.8 9.4 14.2 12.6 12.3 9.0 8.8 8.6 11.2 25.7 15.9 13.3 14.2 7.1 11.0 21.4 11.4 10.4 24.5 11.9 12.6 21.5 7.8 10.5 11.1 19.5 9.8 7.2 10.8 10.8 15.3 9.8 6.5 11.5 29.5 13.6 10.8 14.1 13.5 12.6 4.9 4.0 19.3 6.4 3.6 4.4 3.0 3.1 7.3 7.7 3.9 10.0 9.3 39.4 8.7 8.7 4.6 7.4 4.4 1.4 32.6 2.4 5.7 1.8 5.2 93.7 7.5 8.6 3.7 6.0 6.2 19.8 9.8 5.3 5.5 14.3 8.0 18.4 12.5 12.9 6.1 7.9 8.8 5.0 7.0 1.7 6.5 1.4 24.8 5.3 2.7 2.8 26.1 5.9 3.4 5.5 4.3 1.9 10.1 3.5 13.8 3.5 6.7 2.9 3.1 12.1 7.6 90.1 5.4 2.1 14.4 5.3 5.4 4.8 4.4 4.0 3.9 4.7 3.7 4.1 2.8 4.9 4.0 3.7 19.3 3.6 6.4 4.0 3.8 3.0 11.1 10.8 12.0 11.3 8.8 8.6 14.2 7.1 11.9 11.5 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavourable (2.91e-7)" "prognostic unfavourable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.4 18.2 24.6 14.5 3.4 5.9 14.3 26.3 18.6 36.9 45.6 14.0 14.0 11.9 8.5 12.9 12.2 21.4 16.5 40.8 32.3 8.5 9.3 21.7 13.9 1.3 14.4 11.8 2.1 3.0 28.5 16.2 18.6 11.9 19.0 30.2 11.8 17.9 6.8 19.6 14.3 16.6 16.6 7.6 11.3 12.0 16.7 12.4 14.0 13.5 8.5 11.3 6.9 9.1 19.9 25.2 16.8 23.9 3.7 13.5 17.8 12.6 10.7 27.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898479-112029561 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 20.8;Hep G2: 21.6;HUVEC TERT2: 21.5;RT4: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 10.3;non-classical monocyte: 6.4" "Lineage enriched" "Detected in single" 48 "monocytes: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Approved Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" 29000000 "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: " "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favourable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favourable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 55.1 13.1 12.5 17.8 1.9 31.8 6.2 13.8 10.8 13.8 6.8 27.7 11.5 11.3 25.4 8.4 12.8 11.7 7.1 16.5 6.3 14.2 18.9 12.7 30.3 8.1 10.1 12.9 9.0 23.9 14.3 18.4 18.6 14.1 7.9 20.4 6.8 24.9 6.4 6.4 12.8 13.6 12.2 38.4 12.3 17.3 9.8 1.7 9.9 2.0 8.4 14.1 26.6 0.0 0.2 0.1 10.3 0.0 0.0 0.3 0.5 0.9 4.3 9.7 0.2 0.1 6.9 0.0 0.1 0.5 1.0 20.8 1.3 0.1 4.6 0.0 0.1 5.7 0.0 0.8 0.8 3.0 3.7 0.0 21.6 0.1 0.1 0.8 0.2 0.0 5.0 0.3 21.5 1.1 2.0 1.6 0.9 0.0 4.9 2.7 3.4 1.4 1.2 1.6 10.9 12.9 0.1 4.1 0.1 0.3 1.7 0.0 0.2 3.2 0.6 2.0 0.0 0.0 1.7 2.5 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 6.4 0.1 0.0 0.3 13.1 17.8 6.2 13.8 16.5 6.3 8.1 10.1 18.6 9.8 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672390-116798386 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 45.4;CAPAN-2: 49.6;EFO-21: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "amygdala: 3.5;basal ganglia: 9.9;cerebral cortex: 7.6;hippocampal formation: 8.0;olfactory region: 9.1" "Low region specificity" "Detected in many" "CAB005282, CAB018577, HPA055607" Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" 178550000 70000000 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: " "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 16.2 1.1 1.8 4.5 2.3 4.3 11.2 0.9 15.2 9.9 6.5 2.4 2.4 4.4 7.5 5.2 5.1 4.6 12.3 5.4 5.7 1.8 20.1 30.2 15.6 1.4 3.6 2.1 2.0 9.3 0.7 8.1 24.4 2.6 8.0 6.6 34.1 12.2 8.4 12.8 7.2 8.6 4.0 2.3 5.7 10.6 2.7 2.4 0.5 21.4 7.0 2.1 10.1 15.0 0.2 0.3 1.2 0.2 0.3 0.4 0.0 45.4 26.1 0.0 0.1 2.0 2.0 1.8 26.0 10.6 14.0 11.8 5.4 49.6 2.0 43.3 16.3 12.0 4.5 24.7 28.7 0.1 5.6 0.0 27.1 4.7 0.3 0.0 0.0 2.6 9.8 9.1 30.1 9.6 0.9 0.2 25.9 1.0 0.0 0.0 3.9 26.7 0.0 22.0 0.0 24.6 5.2 3.8 0.0 10.7 3.4 10.1 0.0 0.2 17.7 20.9 7.4 11.0 20.1 0.5 4.0 0.2 23.0 0.0 2.9 1.1 0.2 0.4 0.4 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 1.2 0.3 0.1 0.3 0.1 0.0 1.8 2.3 0.9 15.2 5.7 1.8 3.6 2.1 2.6 2.4 METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase like 1" Q9UBP6 12 57768471-57772793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "RH-30: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm Nucleoplasm "HPA020914: AB_1853830, HPA050450: " "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavourable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" 12.2 16.6 6.7 13.8 8.8 8.4 12.3 2.2 6.9 7.6 7.6 4.5 10.8 3.3 9.4 21.2 10.3 9.0 10.7 8.1 5.8 5.0 20.9 15.3 7.7 8.8 7.4 4.6 17.6 34.9 10.9 10.6 8.3 6.5 11.0 10.3 5.3 17.9 17.2 20.4 8.5 5.7 10.5 5.0 8.2 7.3 11.4 5.4 4.5 15.1 15.6 9.8 8.8 7.8 6.1 12.6 0.7 6.7 7.3 18.6 5.1 5.9 11.0 4.6 4.2 6.2 4.3 6.3 6.5 5.8 10.9 5.9 7.6 8.4 7.2 12.0 7.8 7.2 7.1 10.0 10.6 4.3 8.2 8.4 4.2 9.3 4.4 9.1 4.4 3.8 9.1 12.2 8.5 5.7 7.7 7.3 5.5 11.7 6.3 10.9 10.8 11.0 5.6 77.0 10.7 9.5 7.5 4.9 4.4 6.7 7.5 6.0 9.8 8.6 4.3 4.4 4.9 7.7 8.5 3.4 2.5 8.8 6.2 6.5 9.1 0.0 4.7 0.0 5.3 6.7 18.6 4.7 6.9 6.5 10.3 6.1 9.5 9.2 0.7 7.3 1.1 12.6 3.3 5.1 6.7 8.8 2.2 6.9 5.8 5.0 7.4 4.6 6.5 5.4 METTL11B "C1orf184, HOMT1B" ENSG00000203740 "Methyltransferase like 11B" Q5VVY1 1 170146001-170167790 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "heart muscle: 7.0;skeletal muscle: 3.6" "Cell line enriched" "Detected in single" 12 "NTERA-2: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028049 Uncertain "HPA028049: AB_10610139" "unprognostic (1.12e-1)" "unprognostic (2.57e-1)" "unprognostic (5.62e-2)" "unprognostic (7.59e-2)" "unprognostic (7.25e-2)" "unprognostic (1.19e-1)" "unprognostic (8.68e-2)" "unprognostic (5.24e-2)" "unprognostic (2.76e-3)" "unprognostic (5.43e-2)" "unprognostic (4.56e-1)" "unprognostic (5.79e-4)" 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 METTL16 "METT10D, MGC3329" ENSG00000127804 "Methyltransferase like 16" Q86W50 17 2405562-2511891 "Enzymes, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020352, HPA059798" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA020352: AB_1853828, HPA059798: AB_2684128" "unprognostic (4.94e-3)" "unprognostic (2.86e-2)" "unprognostic (2.29e-2)" "unprognostic (5.66e-3)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (3.35e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-1)" "prognostic favourable (3.06e-4)" "unprognostic (5.35e-2)" "unprognostic (4.85e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-1)" "unprognostic (1.61e-1)" "unprognostic (2.68e-2)" 12.7 14.0 13.1 11.0 15.2 13.1 14.1 22.5 14.4 14.9 13.1 19.8 11.2 8.6 21.6 10.6 11.0 16.5 9.6 12.4 12.6 9.7 11.5 6.9 12.2 13.1 18.3 9.7 22.5 13.5 19.7 22.8 7.5 13.6 13.5 10.4 18.3 12.1 13.1 14.2 14.7 10.4 16.5 14.6 11.1 11.2 11.0 17.5 15.7 16.5 8.8 17.5 15.3 12.7 5.7 3.1 2.3 3.2 2.0 8.1 2.0 6.0 16.1 9.1 8.8 6.9 8.7 8.5 7.7 6.6 8.8 7.3 21.3 3.9 18.9 8.3 6.9 8.7 21.0 10.5 12.0 7.2 13.3 9.7 13.2 9.7 7.5 8.9 7.9 7.3 10.0 12.1 17.8 9.0 12.6 10.2 5.8 6.5 12.7 5.3 10.4 6.8 21.3 9.6 8.5 6.3 5.4 4.8 7.6 11.4 6.3 6.7 7.9 5.7 6.5 8.0 5.2 11.3 11.1 6.0 7.3 13.5 10.9 7.5 10.9 2.3 3.2 1.2 5.7 2.1 7.2 5.7 5.6 5.5 2.2 5.0 8.1 5.9 0.1 2.0 1.5 3.1 3.5 2.0 13.1 15.2 22.5 14.4 12.6 9.7 18.3 9.7 13.6 17.5 METTL3 "M6A, MT-A70, Spo8" ENSG00000165819 "Methyltransferase like 3" Q86U44 14 21498133-21511375 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, Immunity, Innate immunity, Spermatogenesis" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.19e-5)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "prognostic favourable (2.78e-4)" "prognostic favourable (2.72e-4)" "unprognostic (4.52e-2)" "unprognostic (4.64e-3)" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (5.36e-2)" "unprognostic (1.22e-1)" 13.1 21.0 15.7 18.3 20.4 6.8 17.4 27.1 16.4 13.5 12.8 16.3 20.4 7.7 17.1 19.8 14.3 20.9 11.2 17.3 16.3 8.6 14.6 14.0 14.2 18.4 21.7 15.2 18.2 14.2 25.8 21.3 16.0 16.3 19.3 13.9 12.2 17.0 19.3 18.8 17.0 11.9 17.6 13.8 17.5 12.9 21.6 20.6 15.4 19.2 13.3 21.8 15.1 14.8 13.0 12.6 7.7 10.3 15.3 14.3 8.1 16.8 25.2 24.0 9.6 18.6 15.4 12.1 15.5 11.4 18.6 21.9 9.5 20.0 17.6 10.0 9.6 17.9 29.3 15.3 29.5 16.6 17.4 10.9 13.9 37.6 7.6 14.7 12.4 11.5 13.5 11.5 13.6 24.2 13.4 10.1 24.6 12.4 13.0 11.7 20.4 31.1 13.1 19.0 15.6 17.0 11.3 14.9 16.1 16.9 22.3 15.8 17.6 9.7 15.8 6.6 11.1 12.1 10.5 10.7 13.3 12.2 8.1 11.8 14.0 5.1 8.1 7.7 8.7 10.3 12.7 13.0 10.5 9.6 10.5 10.3 11.0 9.7 0.9 15.3 8.4 12.6 14.3 8.1 15.7 20.4 27.1 16.4 16.3 8.6 21.7 15.2 16.3 20.6 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218304 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavourable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 12.6 12.2 13.8 14.5 13.5 27.5 19.4 21.7 13.7 14.7 11.3 10.7 8.8 8.7 13.4 9.5 11.7 11.1 13.0 11.3 15.1 9.1 9.3 10.3 12.0 19.8 16.3 8.3 14.5 10.1 16.6 9.5 11.7 12.3 10.3 9.8 7.6 12.4 10.1 9.0 10.2 12.7 13.6 12.6 16.3 10.5 43.7 12.7 40.0 13.6 9.3 18.4 13.0 17.5 2.8 2.0 10.3 1.3 5.8 3.8 1.5 7.5 4.5 21.8 8.1 12.1 15.0 17.0 10.8 14.1 6.3 7.7 7.2 5.8 15.4 3.8 14.3 13.8 9.4 15.4 12.1 11.3 4.2 3.3 4.5 9.4 19.6 20.9 6.3 12.6 21.7 8.8 27.6 16.2 3.5 27.0 16.2 5.5 15.6 10.4 10.5 4.5 15.8 11.4 15.8 14.5 2.5 9.7 13.3 8.1 4.4 42.5 4.4 11.7 12.1 15.2 10.1 4.6 9.2 19.6 2.9 24.6 10.4 10.6 34.3 10.3 1.3 1.5 3.6 1.3 3.1 2.8 3.8 3.7 2.0 2.1 1.6 3.8 0.7 5.8 0.9 2.0 3.1 1.5 13.8 13.5 21.7 13.7 15.1 9.1 16.3 8.3 12.3 12.7 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 72.7;lymphoid tissue: 42.1" "Cell line enhanced" "Detected in many" "Daudi: 32.2;HL-60: 40.5;HMC-1: 53.7;HUVEC TERT2: 43.3;U-698: 31.1;U-937: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" 28000 Vesicles "HPA048936: , HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavourable (5.12e-4)" "prognostic favourable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 10.0 4.5 2.6 16.6 5.1 14.4 13.4 1.0 3.3 6.0 6.5 3.0 2.0 3.7 6.5 3.5 4.4 7.1 6.3 6.7 2.8 2.6 6.1 5.6 14.9 42.1 5.6 1.2 3.6 3.7 0.8 2.2 14.0 8.3 5.6 3.7 4.4 5.7 2.5 3.4 3.0 14.1 5.1 4.4 37.6 4.1 2.6 3.6 33.9 6.3 4.5 19.3 8.8 4.2 24.1 40.5 72.7 40.8 40.9 53.3 53.2 1.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.6 32.2 0.1 0.0 2.3 9.4 1.8 0.0 12.7 0.2 24.8 0.1 0.3 0.1 40.5 53.7 0.0 0.5 0.3 0.7 43.3 0.1 15.3 0.0 0.1 4.6 0.5 0.1 0.1 11.9 0.4 24.2 0.1 0.0 19.4 0.1 0.1 0.0 0.0 0.2 2.8 24.1 0.0 1.2 4.8 0.1 0.0 0.1 31.1 0.2 36.4 0.5 36.8 40.1 72.7 41.3 38.8 45.1 21.8 48.0 43.3 40.5 24.1 52.9 45.5 25.5 40.9 40.8 10.1 53.3 53.2 2.6 5.1 1.0 3.3 2.8 2.6 5.6 1.2 8.3 3.6 MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" P26572 5 180784782-180815652 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved 7200000 "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavourable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" 67.7 20.9 14.9 30.8 20.1 25.5 53.3 15.6 19.3 22.3 29.0 14.6 22.4 24.8 26.1 26.8 31.2 26.4 19.8 26.4 16.1 10.6 20.8 55.6 42.7 50.5 25.6 10.3 27.2 37.1 8.5 20.8 84.9 17.7 26.6 15.3 24.1 28.4 21.8 18.5 22.9 35.1 20.7 31.1 45.7 24.5 19.2 21.9 27.0 32.1 16.9 29.8 38.2 39.1 13.2 40.8 37.7 54.9 16.5 24.9 47.2 14.1 14.2 7.8 16.7 41.5 18.9 27.4 33.8 41.6 21.2 26.5 20.3 11.7 12.1 19.0 32.6 17.0 4.2 50.4 12.6 65.1 11.7 10.6 8.2 15.7 20.2 9.7 34.9 21.9 24.2 17.1 17.1 18.3 6.1 21.8 18.9 20.1 9.1 13.9 7.6 18.4 11.1 11.5 15.9 8.1 16.9 6.7 8.1 14.1 14.6 27.9 11.2 17.4 19.6 25.9 11.6 11.0 15.2 41.3 34.1 10.6 21.1 19.7 13.0 19.5 54.9 25.3 22.4 45.9 24.9 13.2 16.4 18.7 40.8 12.1 14.4 16.0 37.7 16.5 35.1 38.9 18.8 47.2 14.9 20.1 15.6 19.3 16.1 10.6 25.6 10.3 17.7 21.9 MGAT2 GNT-II ENSG00000168282 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" Q10469 14 49620795-49623481 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" 5000000 "Golgi apparatus" "HPA043721: , HPA056824: " "unprognostic (1.20e-2)" "prognostic unfavourable (3.22e-4)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (3.77e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (7.44e-2)" "unprognostic (7.12e-2)" "unprognostic (5.63e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-2)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" 14.0 17.0 7.4 14.0 7.1 5.0 12.3 7.3 8.4 11.7 16.5 7.8 16.5 13.9 12.9 14.1 11.7 11.4 16.8 10.1 6.2 6.6 13.2 34.4 10.3 20.5 6.1 7.2 15.3 27.9 4.8 8.2 14.1 5.8 9.4 13.7 10.7 34.9 19.1 5.1 6.3 29.1 9.7 7.1 20.9 12.3 27.7 5.8 18.2 9.0 7.2 14.8 11.6 9.1 15.5 28.2 22.1 22.8 12.0 24.7 23.2 18.7 9.3 7.1 12.0 17.0 16.5 4.6 20.8 20.7 19.3 17.5 11.2 14.3 19.0 17.8 18.9 15.0 10.0 12.0 20.9 19.4 8.9 12.1 6.9 11.0 13.4 27.8 28.4 12.6 9.7 11.4 16.2 23.1 9.2 52.6 20.3 7.1 9.6 17.8 7.3 15.0 10.9 20.8 16.4 15.1 10.9 7.4 8.0 14.9 3.9 11.7 12.0 19.0 23.9 17.6 19.1 12.7 14.8 56.9 27.3 17.0 8.5 13.9 11.8 21.7 22.8 22.1 23.0 20.0 24.7 15.5 21.3 20.7 23.6 10.4 12.6 17.3 6.8 12.0 21.6 28.2 18.2 23.2 7.4 7.1 7.3 8.4 6.2 6.6 6.1 7.2 5.8 5.8 MGAT3 GNT-III ENSG00000128268 "Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase" Q09327 22 39457344-39492194 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0;intestine: 27.1" "Cell line enhanced" "Detected in some" "BEWO: 28.7;HMC-1: 24.8;U-266/70: 32.2;U-266/84: 13.0;U-698: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.5;eosinophil: 3.3;memory B-cell: 1.7;naive B-cell: 1.2" "Group enriched" "Detected in many" 9 "B-cells: 1.7;granulocytes: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" 78000 "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavourable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 5.3 1.2 17.1 3.9 18.7 9.2 3.6 29.0 24.6 7.1 11.9 8.9 0.0 21.1 3.4 1.2 1.4 4.0 7.9 3.0 18.1 14.9 3.3 0.4 14.9 7.2 13.1 13.4 1.0 3.1 0.9 1.4 10.5 10.7 1.0 4.9 1.7 2.1 1.4 1.6 2.5 27.1 3.2 10.4 3.3 7.8 4.9 9.0 0.2 1.1 0.0 8.9 3.0 2.7 1.7 0.1 3.5 0.2 0.0 0.2 0.1 0.1 0.1 4.7 0.4 0.0 0.0 28.7 0.2 0.3 0.2 0.0 6.3 1.6 9.9 3.5 0.0 0.5 2.4 0.0 0.0 0.0 0.2 8.0 0.0 0.0 0.1 0.0 24.8 0.0 0.0 0.0 0.0 0.0 6.5 1.2 0.0 0.1 0.2 0.6 1.4 0.0 0.5 0.0 1.6 0.2 0.2 2.6 1.9 0.0 0.0 0.0 0.3 0.4 0.0 0.0 3.7 0.0 0.0 32.2 13.0 13.9 0.0 0.0 0.7 3.5 0.1 3.3 0.1 0.2 0.1 1.7 0.0 0.0 0.1 1.2 0.2 0.2 0.4 0.0 0.0 0.0 0.1 0.1 17.1 18.7 29.0 24.6 18.1 14.9 13.1 13.4 10.7 9.0 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A" Q9UM21 2 98619106-98731126 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.2" "Cell line enhanced" "Detected in many" "BEWO: 47.2;HUVEC TERT2: 17.6;TIME: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted in other tissues" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavourable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavourable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 8.1 5.1 11.3 11.9 15.6 49.2 8.2 28.5 14.3 6.1 14.6 8.3 6.8 17.6 5.2 4.1 4.1 6.2 8.0 5.1 11.3 10.4 17.1 6.0 13.7 16.7 9.9 8.3 2.9 26.7 33.3 14.1 11.9 10.4 6.6 15.8 5.6 14.5 4.4 3.3 3.4 38.5 7.2 16.1 7.0 8.4 3.9 14.3 20.3 6.4 3.1 11.6 8.3 5.0 2.0 9.3 7.6 2.9 7.7 19.7 7.4 3.1 0.6 1.2 2.6 0.0 0.0 47.2 0.0 0.0 0.3 0.0 7.5 3.8 0.0 7.1 0.0 0.1 2.6 0.3 0.0 3.7 2.8 0.2 0.0 13.0 0.0 6.2 2.3 0.0 1.7 0.0 0.2 17.6 0.5 3.4 0.0 6.1 13.7 10.9 0.4 0.5 3.4 0.0 3.7 9.2 6.3 3.8 1.2 0.9 11.8 1.7 2.8 8.5 28.5 0.0 1.5 0.0 0.9 1.2 2.6 0.8 0.0 9.5 0.2 3.3 2.9 6.6 12.3 0.5 15.9 2.0 14.9 13.7 2.0 1.1 19.7 16.1 7.6 7.7 1.1 9.3 8.4 7.4 11.3 15.6 28.5 14.3 11.3 10.4 9.9 8.3 10.4 14.3 MGAT4B GnT-Ivb ENSG00000161013 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B" Q9UQ53 5 179797597-179806952 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 125.6;liver: 100.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9 "eosinophil: 8.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052134 Uncertain "Intracellular and membrane" "HPA052134: " "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavourable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favourable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 13.2 22.8 9.1 19.5 8.2 9.5 18.7 15.3 13.5 8.7 77.3 5.9 10.1 61.7 9.2 10.4 16.8 10.7 26.0 20.6 9.5 5.4 31.9 100.0 17.1 15.6 6.3 5.2 9.1 13.4 10.3 8.3 14.4 6.3 8.8 30.9 10.1 19.2 8.2 8.4 12.1 125.6 7.5 4.9 12.5 22.3 11.2 5.6 7.0 16.6 14.6 10.0 9.5 13.7 0.9 0.6 8.5 0.7 0.0 0.6 0.2 21.9 22.2 10.9 25.3 33.6 18.0 19.0 13.0 26.2 11.9 9.4 24.3 61.1 3.7 33.5 30.0 16.6 16.0 29.3 9.0 30.6 8.5 11.2 20.1 21.2 23.7 14.2 3.5 19.5 20.6 12.0 15.0 24.4 7.3 10.1 20.0 24.4 2.1 11.8 6.7 8.9 5.5 8.7 10.4 35.6 42.6 18.0 10.6 19.5 20.2 35.1 13.8 14.4 29.7 30.0 13.3 16.8 20.8 8.6 9.9 9.3 36.0 17.8 21.6 0.0 0.7 8.5 0.3 0.1 0.1 0.0 0.5 0.2 0.6 0.9 0.4 0.6 0.3 0.0 0.5 0.5 0.0 0.2 9.1 8.2 15.3 13.5 9.5 5.4 6.3 5.2 6.3 5.6 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 12.8;epididymis: 10.9;pituitary gland: 25.9;testis: 7.8;thyroid gland: 18.0" "Group enriched" "Detected in some" 13 "NTERA-2: 10.9;SCLC-21H: 4.8" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016418 Approved "HPA016418: AB_1853854" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 1.0 3.0 5.5 1.0 12.3 1.1 0.9 4.9 12.8 1.3 1.2 2.5 0.4 0.9 1.0 10.9 1.1 1.1 1.2 3.6 9.4 3.9 1.0 0.9 1.0 0.9 3.0 9.3 0.9 0.9 0.9 25.9 0.8 10.6 1.1 1.2 0.0 0.9 2.4 0.8 1.0 1.0 1.0 4.3 0.9 1.0 7.8 5.1 0.0 18.0 0.0 0.8 0.9 0.6 0.5 0.3 0.8 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.0 10.9 0.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.1 0.8 0.2 0.1 0.3 0.2 0.0 5.5 12.3 4.9 12.8 9.4 3.9 3.0 9.3 10.6 5.1 MGAT5 GNT-V ENSG00000152127 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved 96000 "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" 8.4 9.8 13.0 21.7 15.7 12.0 8.0 21.3 17.6 9.0 13.2 17.2 4.6 14.2 8.5 6.3 8.2 17.5 15.1 33.9 13.9 17.5 14.3 4.9 9.3 20.1 23.6 11.6 11.3 11.1 18.8 7.9 22.0 28.0 7.9 13.8 8.3 11.9 9.1 3.2 6.6 19.2 10.1 28.7 23.1 15.0 6.6 13.2 16.5 10.3 5.1 28.9 11.0 9.2 7.5 1.8 2.3 0.8 2.4 3.1 1.1 10.0 4.0 10.3 7.3 9.2 17.6 7.2 13.4 20.5 5.4 4.6 1.6 5.0 16.1 10.3 10.6 3.5 8.0 6.3 10.4 15.7 4.7 9.0 5.2 21.0 6.0 8.7 32.2 4.8 6.6 11.4 7.1 40.4 4.6 11.0 9.8 6.4 4.7 4.1 4.7 10.0 5.8 12.1 10.1 4.2 12.3 17.0 21.0 4.3 3.7 25.6 2.9 6.1 18.2 17.2 9.1 12.4 7.0 3.1 1.4 6.1 14.4 12.6 27.2 1.2 0.7 1.8 1.6 0.7 2.7 5.6 3.1 2.1 0.6 7.5 1.3 1.6 2.3 2.4 0.8 1.8 1.9 1.1 13.0 15.7 21.3 17.2 13.9 17.5 23.6 11.6 28.0 13.2 MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B" Q3V5L5 17 76868456-76950393 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 28.1" "Cell line enhanced" "Detected in many" "A549: 21.6;SCLC-21H: 11.1;U-138 MG: 13.1;U-2 OS: 14.2" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: " "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" 1.1 1.2 9.3 1.1 13.4 1.0 0.9 4.4 28.1 1.0 0.9 1.1 0.0 0.8 1.1 0.7 0.9 1.0 0.9 0.8 5.5 2.8 0.9 0.7 1.0 0.9 2.3 8.1 1.2 0.8 1.0 0.6 1.1 2.6 0.8 0.8 1.1 0.8 0.8 0.7 0.9 0.9 0.8 0.7 1.4 1.0 2.3 1.7 0.0 0.8 0.0 0.9 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 21.6 4.4 2.2 0.0 0.0 2.3 0.3 0.9 7.9 4.7 0.0 0.5 0.0 1.7 1.0 0.1 1.0 0.2 2.1 0.0 0.3 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 1.2 1.4 0.1 0.0 0.0 1.0 0.0 0.0 1.2 2.2 3.0 3.8 4.5 6.2 0.0 11.1 4.2 3.8 1.7 3.4 0.1 0.1 4.0 13.1 14.2 0.2 4.1 0.0 0.0 0.5 0.4 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 13.4 4.4 27.4 5.5 2.8 2.3 8.1 2.6 1.7 MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467184-129768007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: , HPA032136: , HPA069497: " "unprognostic (1.10e-1)" "prognostic favourable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favourable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" 11.7 11.3 7.4 15.5 7.6 7.1 11.3 3.5 9.1 8.3 12.2 10.0 19.6 10.8 15.3 17.1 9.9 15.2 14.1 10.5 7.1 7.1 12.6 45.6 7.5 11.6 8.6 6.6 12.3 16.5 5.7 5.8 4.5 9.2 11.2 3.4 11.8 14.9 24.5 14.4 9.2 9.6 10.9 8.1 8.6 9.9 11.7 3.9 16.0 10.2 14.9 14.7 12.6 13.0 20.3 17.7 6.5 15.3 18.2 21.2 16.6 0.0 2.6 2.8 13.3 5.8 12.1 10.4 5.9 6.6 4.3 4.2 16.2 17.3 12.1 9.5 7.6 7.9 1.7 6.3 1.9 0.0 1.0 2.4 5.9 10.3 9.0 0.2 6.9 7.7 0.0 2.5 0.0 0.0 0.0 8.5 5.3 21.8 9.5 12.4 0.6 10.4 11.0 0.0 4.7 7.9 5.9 2.8 7.0 7.1 2.9 0.0 11.4 9.4 0.0 5.7 2.9 0.0 0.0 0.0 0.0 6.1 0.0 3.9 0.0 2.6 15.3 6.5 19.1 14.8 18.6 20.3 17.5 17.8 15.8 19.9 17.6 18.9 1.8 18.2 13.7 17.7 21.2 16.6 7.4 7.6 3.5 9.1 7.1 7.1 8.6 6.6 9.2 3.9 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 16.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 16.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Approved Vesicles Vesicles "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 18.7 23.1 22.9 24.0 24.3 29.7 19.9 43.1 37.6 16.3 16.6 28.7 16.8 28.9 23.7 13.8 14.7 20.9 20.2 20.7 24.3 18.6 15.9 30.4 21.6 22.2 27.9 21.5 21.3 34.9 19.7 21.5 18.8 18.6 19.0 11.6 20.7 23.8 22.9 29.9 13.5 28.6 20.0 17.2 26.2 25.2 11.5 24.5 12.9 19.7 10.4 11.0 18.7 14.2 1.7 4.1 16.6 3.9 1.4 3.3 2.9 5.2 25.1 13.0 13.3 7.8 7.6 17.8 11.3 8.0 9.6 8.1 16.6 12.6 15.6 14.7 13.7 8.5 10.4 9.3 2.8 21.6 11.5 8.5 17.6 22.8 14.3 12.3 21.2 14.1 6.1 13.3 5.7 9.1 12.4 11.4 6.5 23.1 12.8 16.5 19.2 11.0 23.5 6.8 20.9 8.4 15.4 20.9 17.4 18.8 20.3 11.3 12.3 12.2 16.1 17.8 9.9 50.1 9.7 18.2 14.1 10.5 7.6 12.4 12.8 4.5 3.5 3.4 2.7 3.9 2.5 1.4 1.5 2.3 2.3 1.7 3.3 2.0 16.6 1.4 2.4 4.1 1.7 2.9 22.9 24.3 43.1 37.6 24.3 18.6 27.9 21.5 18.6 24.5 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 382.8" "Cell line enhanced" "Detected in many" "ASC diff: 335.0;ASC TERT1: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 46.1;myeloid DC: 34.1" "Group enriched" "Detected in many" 15 "dendritic cells: 34.1;monocytes: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavourable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favourable (1.97e-4)" "unprognostic (4.19e-1)" 127.9 106.0 18.5 10.8 32.6 9.5 116.8 10.3 14.0 9.3 39.7 9.6 2.6 17.0 4.1 6.4 19.5 6.9 26.6 12.1 19.6 13.9 56.9 382.8 42.0 2.7 18.9 8.9 3.1 12.4 0.8 5.3 8.7 18.4 23.5 28.3 3.0 14.7 8.2 8.9 7.0 15.5 11.5 20.1 0.9 10.3 6.8 12.0 0.0 69.9 13.9 3.6 32.6 37.2 0.2 34.1 2.7 46.1 0.0 0.2 13.0 0.0 30.0 7.1 8.3 335.0 129.3 0.0 24.6 25.2 13.4 20.9 11.3 50.2 0.0 3.0 31.4 0.1 18.6 39.3 12.2 0.0 2.5 10.2 16.6 39.9 78.3 19.8 0.0 83.9 43.9 40.9 43.2 23.5 7.2 0.0 28.8 6.1 0.0 8.0 59.7 23.8 0.0 4.2 13.5 30.2 59.3 1.3 1.0 38.4 24.6 1.0 26.6 11.2 14.8 13.8 1.8 27.1 31.7 0.0 0.0 0.0 45.5 31.6 0.4 2.7 46.1 0.4 0.0 7.0 0.1 0.2 0.0 0.0 34.1 0.0 0.0 0.0 1.5 0.0 1.5 9.6 0.2 13.0 18.5 32.6 10.3 14.0 19.6 13.9 18.9 8.9 18.4 12.0 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 53.8;U-937: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 46.9" "Group enriched" "Detected in many" 4 "dendritic cells: 46.9;monocytes: 25.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA010707 Approved "HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favourable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favourable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 26.9 30.2 6.9 9.7 10.8 7.4 29.0 12.6 9.3 16.4 27.3 7.3 31.3 27.3 12.2 19.4 54.9 14.7 42.0 26.9 7.4 9.0 25.3 79.1 20.6 21.6 10.1 5.9 10.6 27.8 16.4 18.2 19.2 10.2 23.3 25.4 14.7 30.4 36.7 20.4 24.2 60.3 13.3 10.7 19.6 15.2 29.0 8.8 8.3 23.7 40.9 26.8 19.1 22.6 0.5 46.9 8.1 25.9 5.8 8.8 8.8 7.5 11.1 5.7 0.0 0.9 3.0 3.5 1.3 12.5 0.6 2.1 11.5 53.8 0.0 31.5 3.3 14.4 10.1 15.5 0.9 4.2 9.1 33.3 12.1 45.4 2.7 28.6 25.7 10.5 38.2 0.4 2.4 31.5 13.8 5.1 4.5 6.2 0.0 4.6 1.3 11.2 2.3 6.6 10.1 29.3 16.3 14.4 4.3 10.2 16.0 12.1 10.2 38.0 19.9 1.1 5.5 1.5 1.2 5.9 4.0 1.8 0.7 48.5 2.5 8.1 25.9 7.0 1.1 15.4 0.7 0.3 1.9 0.9 35.7 0.5 0.6 0.6 4.4 5.8 4.8 46.9 8.8 8.8 6.9 10.8 12.6 9.3 7.4 9.0 10.1 5.9 10.2 8.8 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165630861-165661796 "Enzymes, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 92.7;HDLM-2: 98.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053311 Approved Nucleoplasm 40000 Nucleoplasm "HPA053311: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 42.8 30.8 52.5 9.7 30.5 19.0 51.2 17.9 56.0 18.4 39.7 18.4 19.1 65.2 19.5 101.8 19.7 20.6 26.5 133.6 38.1 33.9 45.2 29.5 20.8 11.0 44.2 37.6 22.7 17.7 11.1 18.3 30.9 39.6 21.2 40.4 20.3 29.8 20.6 87.2 15.6 53.4 24.7 38.7 12.4 29.8 19.4 23.3 2.7 25.7 41.8 8.2 19.9 17.3 21.3 35.1 20.7 47.0 15.7 38.0 40.7 23.1 17.0 18.4 14.5 64.7 38.9 92.7 19.4 31.3 15.1 26.4 17.7 30.3 1.4 15.4 23.7 28.4 4.5 19.0 15.3 98.4 11.5 3.5 13.4 8.0 18.2 5.6 7.8 33.2 15.3 20.9 8.0 24.6 8.7 8.9 28.3 5.1 6.1 12.8 40.3 21.9 5.8 7.9 2.9 79.8 21.7 14.3 17.5 19.5 25.4 38.6 19.2 27.3 22.3 18.8 11.2 12.9 14.0 6.6 4.5 0.8 34.8 14.7 12.0 10.4 45.7 20.7 30.1 37.0 30.3 21.3 38.0 33.5 35.1 19.9 24.4 26.7 9.8 15.7 47.0 15.1 32.3 40.7 52.5 30.5 17.9 56.0 38.1 33.9 44.2 37.6 39.6 23.3 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 12.1 9.1 15.3 7.9 20.6 5.9 15.7 16.1 17.4 16.6 10.9 16.3 9.7 6.9 19.1 13.7 11.4 11.5 12.0 9.4 16.3 12.9 15.7 14.1 10.1 9.6 17.4 16.5 17.2 11.7 18.4 11.5 14.9 15.5 14.7 10.1 14.6 12.0 12.6 9.6 12.5 8.4 17.9 13.8 9.4 10.7 11.5 18.1 13.9 19.1 9.8 10.6 13.0 13.8 1.2 1.2 3.5 1.7 2.5 2.0 0.6 8.4 3.3 16.5 11.4 8.8 10.6 3.9 6.8 7.6 4.9 7.1 4.9 3.1 7.2 6.3 9.4 5.7 9.6 9.2 11.1 9.4 4.5 8.0 4.3 6.8 7.2 16.3 3.4 6.8 10.2 5.7 14.7 12.2 11.0 21.3 7.5 4.1 7.8 6.2 4.2 4.4 51.5 13.6 17.8 8.3 7.5 5.4 13.3 11.7 5.4 6.0 3.9 10.7 10.4 12.5 6.3 5.2 9.0 11.2 3.9 11.1 5.3 10.4 7.4 3.5 1.7 0.6 1.0 0.9 1.2 1.2 1.5 1.0 0.6 0.6 1.2 0.9 1.5 2.5 0.5 1.2 2.0 0.6 15.3 20.6 16.1 17.4 16.3 12.9 17.4 16.5 15.5 18.1 MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "Mindbomb E3 ubiquitin protein ligase 2" Q96AX9 1 1615415-1630610 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 72.5" "Cell line enhanced" "Detected in many" "HaCaT: 13.1;SCLC-21H: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced "HPA068322: " "unprognostic (3.93e-2)" "unprognostic (6.02e-2)" "unprognostic (2.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.17e-2)" "unprognostic (2.22e-3)" "unprognostic (1.29e-1)" "unprognostic (3.58e-2)" "unprognostic (2.49e-1)" "unprognostic (1.01e-2)" 6.4 3.9 8.7 6.4 10.0 4.5 4.7 8.8 11.5 4.8 6.9 7.1 4.7 5.3 5.1 5.4 11.4 4.1 3.7 6.1 9.1 7.9 5.5 6.2 5.1 3.7 5.3 7.1 5.8 7.0 3.7 9.4 4.0 5.7 4.7 3.7 6.6 5.4 6.5 72.5 9.6 4.6 5.4 3.4 9.0 8.5 5.2 5.8 7.4 5.9 9.7 4.1 4.5 4.1 2.9 9.2 1.9 0.1 7.3 4.7 1.0 6.5 0.9 0.4 1.5 1.7 0.6 9.1 3.1 1.4 1.0 2.3 1.3 1.6 0.7 4.4 0.9 13.1 0.5 2.0 0.0 3.4 5.6 0.5 1.9 1.2 2.4 0.8 2.2 1.4 1.4 0.6 0.2 0.5 2.6 1.2 0.2 1.0 3.6 8.3 1.1 10.4 6.1 1.9 8.9 0.1 0.8 14.0 5.1 5.2 0.7 5.0 1.0 3.2 0.6 0.9 2.1 5.1 0.9 6.8 2.0 1.8 2.3 2.6 1.1 0.0 0.1 1.9 4.3 0.1 4.3 2.6 3.3 4.7 0.0 2.9 3.9 2.9 0.5 7.3 0.0 9.2 2.3 1.0 8.7 10.0 8.8 11.5 9.1 7.9 5.3 7.1 5.7 5.8 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 56.8;AF22: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Approved "Centriolar satellite" "Centriolar satellite" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 13.4 3.6 6.5 10.4 8.4 0.3 8.6 16.3 7.1 17.5 21.5 3.8 11.7 7.7 17.9 11.3 12.2 7.7 13.1 13.2 6.2 4.2 7.9 4.9 10.4 4.2 4.5 3.7 12.0 4.8 2.7 6.6 7.8 4.9 14.6 12.8 15.9 7.1 19.1 2.8 3.9 8.7 30.6 2.6 1.3 5.3 6.5 4.1 0.8 6.2 7.1 5.8 17.1 20.5 1.0 0.7 3.3 0.0 0.0 0.1 0.1 12.2 56.8 43.0 6.6 2.5 3.6 5.3 7.7 6.4 7.9 8.1 10.4 3.7 4.1 2.5 7.0 8.4 3.5 5.3 5.9 0.2 5.1 0.9 8.1 0.2 1.1 0.0 0.2 4.1 2.8 5.2 5.5 7.6 0.6 0.7 3.1 1.9 1.6 0.1 13.7 4.1 1.2 11.0 0.0 5.8 11.3 3.0 1.1 3.3 9.7 3.6 6.7 0.0 4.8 2.6 0.3 13.3 6.7 0.6 0.3 0.1 5.6 0.0 12.8 0.1 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.1 6.5 8.4 16.3 5.2 6.2 4.2 4.5 3.7 4.9 4.1 MID2 "FXY2, MRX101, RNF60, TRIM1" ENSG00000080561 "Midline 2" Q9UJV3 X 107825755-107927193 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 23.8;Karpas-707: 20.8;MCF7: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 4.2" "Lineage enriched" "Detected in single" 5 "T-cells: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (8.28e-2)" "unprognostic (8.51e-2)" "unprognostic (3.69e-4)" "unprognostic (6.40e-3)" "unprognostic (1.16e-1)" "unprognostic (7.50e-2)" "unprognostic (3.87e-1)" "unprognostic (7.20e-2)" "unprognostic (1.09e-2)" "unprognostic (4.87e-2)" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.19e-2)" "prognostic unfavourable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (3.77e-1)" "unprognostic (5.97e-3)" 12.7 11.3 3.6 4.8 11.4 0.4 13.0 9.3 8.0 10.8 9.0 5.1 9.4 2.0 12.6 9.7 15.1 10.0 8.6 4.4 4.0 5.2 6.6 6.2 9.0 6.2 4.3 5.8 11.5 10.2 16.0 11.1 4.7 7.1 12.9 4.0 12.4 12.7 10.9 16.6 14.5 4.6 17.2 5.4 5.8 7.7 4.7 4.7 0.5 14.5 8.3 6.6 16.7 11.9 0.7 0.0 0.0 0.0 0.0 4.2 1.1 4.7 4.1 0.1 6.6 5.3 7.5 0.1 3.4 8.6 2.9 2.2 0.3 0.8 0.0 4.5 6.5 3.0 2.4 6.9 0.7 0.0 3.2 0.0 2.5 0.0 7.9 0.0 0.0 4.7 7.9 0.1 8.7 23.8 0.0 20.8 3.2 15.1 0.0 0.0 0.7 7.6 0.0 1.9 0.0 3.6 4.3 0.4 0.0 7.2 0.3 10.9 2.7 0.2 4.9 0.0 1.2 5.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.3 0.1 1.8 3.5 0.0 0.7 4.2 2.3 0.0 0.0 0.0 0.0 0.3 1.1 3.6 11.4 9.3 8.0 4.0 5.2 4.3 5.8 7.1 4.7 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833388-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved "HPA056296: " "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favourable (2.77e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 12.7 14.8 31.4 18.2 46.8 14.9 14.2 30.8 43.5 15.2 26.0 32.6 8.8 33.1 12.4 7.7 40.0 14.3 15.6 9.0 28.4 12.8 13.8 10.0 23.3 17.1 28.6 27.3 27.5 21.5 16.5 15.4 17.4 29.0 14.3 20.7 14.5 21.1 11.3 8.3 47.3 31.1 11.4 24.8 20.0 22.3 14.5 30.9 9.0 12.7 14.6 16.8 14.9 24.1 2.6 1.2 6.4 1.6 0.3 3.0 2.3 18.4 33.9 7.9 12.8 12.6 9.2 22.8 14.8 13.5 11.8 10.0 12.8 12.9 13.2 17.1 15.5 37.6 5.9 26.6 5.8 18.9 16.5 9.4 21.5 10.0 8.3 3.5 18.5 9.8 20.0 11.1 10.3 12.7 10.1 11.5 8.7 11.0 5.6 8.0 6.2 11.0 7.0 6.5 8.0 18.1 19.0 8.3 6.6 15.3 12.8 9.6 11.5 4.9 18.4 12.6 5.7 21.3 14.0 6.6 5.3 2.7 11.3 7.6 8.5 0.0 1.6 6.4 2.7 1.6 3.0 2.6 2.8 2.1 1.2 1.5 2.0 0.8 1.3 0.3 0.8 0.8 2.8 2.3 31.4 46.8 30.8 43.5 28.4 12.8 28.6 27.3 29.0 30.9 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: " "unprognostic (4.05e-3)" "prognostic favourable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavourable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavourable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.3 13.1 8.7 9.6 7.8 11.6 11.6 9.8 9.8 11.9 16.2 15.1 8.0 12.8 12.1 9.8 23.5 14.5 16.0 12.7 21.9 12.9 27.0 15.0 12.9 12.2 14.4 22.0 15.2 11.1 15.5 8.5 13.9 14.1 9.4 6.4 12.7 10.3 12.9 5.9 15.6 9.5 18.2 12.8 12.7 20.3 6.1 5.5 18.9 17.1 15.8 11.5 16.1 11.2 4.3 0.9 13.5 10.9 8.0 13.3 10.9 8.4 18.6 7.9 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Cell line enhanced" "Detected in all" "HHSteC: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: " "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favourable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favourable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.1 14.8 6.3 13.8 46.9 17.0 14.2 7.8 5.6 5.6 5.7 9.5 23.1 18.6 10.8 15.7 16.3 7.9 22.8 2.5 25.3 7.4 7.5 12.5 10.1 78.8 14.7 13.6 18.1 55.5 10.6 22.6 13.2 12.9 33.3 3.8 7.7 8.8 12.3 16.5 16.2 16.9 1.8 23.5 9.9 8.6 8.7 10.4 18.3 27.1 33.4 11.2 18.3 19.8 2.0 8.0 8.2 9.3 54.3 21.0 18.2 16.5 11.1 3.7 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453040-140479569 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA000567: AB_1079299" "unprognostic (9.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (4.87e-3)" "unprognostic (1.24e-2)" "unprognostic (8.02e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-3)" "unprognostic (5.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.22e-2)" 16.8 17.6 26.8 20.8 28.8 69.9 20.1 37.2 32.6 20.4 39.6 16.1 19.7 28.4 20.1 18.6 23.3 22.2 22.4 38.5 24.9 29.8 20.6 17.5 23.6 18.3 25.7 23.3 24.9 27.3 28.2 21.5 31.7 29.4 21.0 33.7 19.4 24.8 23.1 38.5 24.4 26.6 26.3 20.5 22.5 21.7 95.4 20.2 21.0 23.6 18.8 22.3 25.3 36.4 13.1 7.5 39.3 10.5 12.8 17.8 6.4 27.9 21.6 16.9 25.0 26.8 23.5 23.9 19.3 25.1 15.2 17.6 8.8 29.5 20.3 30.3 18.8 13.6 19.0 21.2 19.3 40.2 16.5 21.1 13.0 16.3 21.6 18.0 32.7 23.4 32.0 17.1 16.2 15.1 16.6 25.7 14.6 24.1 21.1 32.4 43.4 16.0 15.3 14.5 31.1 24.4 32.4 23.4 24.2 24.2 32.8 34.5 16.1 15.7 21.4 10.7 8.5 26.1 17.6 61.3 44.9 17.8 30.6 28.4 22.0 19.4 9.2 39.3 6.7 8.7 8.0 13.1 13.0 10.1 7.5 10.9 17.8 11.3 18.1 12.8 10.5 2.5 14.0 6.4 26.8 28.8 37.2 32.6 24.9 29.8 25.7 23.3 29.4 20.2 MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557014-12583713 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037559: AB_10672460, HPA037560: AB_10696936" "unprognostic (4.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-2)" "unprognostic (5.99e-2)" "unprognostic (3.89e-2)" "unprognostic (1.47e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (4.38e-1)" "unprognostic (8.49e-2)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-3)" "prognostic favourable (6.04e-4)" "unprognostic (3.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-2)" "unprognostic (3.32e-2)" 13.7 10.4 15.1 11.1 18.3 16.4 11.6 29.3 19.5 13.7 12.7 12.4 16.1 12.5 15.2 12.3 16.2 13.1 10.9 26.3 14.0 15.1 13.7 12.5 12.1 12.6 15.2 14.8 20.8 26.6 17.3 11.9 14.4 16.0 11.3 11.5 13.2 12.8 13.1 24.5 12.8 10.9 15.9 16.2 10.1 11.7 46.1 14.7 15.4 18.2 17.0 13.7 13.0 12.6 21.3 19.0 30.0 20.3 25.3 26.2 18.7 10.7 12.4 14.8 11.1 23.2 22.6 28.7 16.6 17.8 21.2 17.8 12.0 10.7 15.2 9.5 18.3 6.6 19.3 16.3 18.9 17.2 16.2 21.7 14.2 16.0 26.7 21.3 9.9 25.1 15.2 24.6 15.6 17.4 20.2 21.6 18.2 15.1 26.1 11.1 9.9 21.8 25.2 14.3 17.1 14.9 14.2 8.7 14.7 14.4 7.4 14.8 16.7 18.9 17.5 14.5 14.3 17.2 22.5 16.4 33.6 32.7 15.7 25.5 21.8 18.9 17.2 30.0 21.5 15.6 26.2 21.3 22.1 22.0 19.0 16.4 23.9 22.3 15.0 25.3 20.3 15.1 23.4 18.7 15.1 18.3 29.3 19.2 14.0 15.1 15.2 14.8 16.0 14.7 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565678-23630075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell line enhanced" "Detected in many" "K-562: 17.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 4 "T-cells: 5.7" "Low region specificity" "Detected in many" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 1.0 0.7 5.1 1.2 10.4 4.0 1.2 1.0 11.1 0.5 1.1 8.4 0.0 1.3 1.3 3.2 5.6 0.9 0.8 0.8 6.4 3.4 1.1 0.7 1.0 1.9 14.4 3.0 1.2 1.7 0.5 3.8 8.5 5.1 1.2 0.8 3.1 5.2 1.0 1.4 1.2 1.9 0.8 8.2 1.5 0.9 5.7 13.3 5.0 0.9 1.1 1.7 0.7 0.6 1.0 0.9 1.3 0.5 0.4 5.7 0.7 4.7 3.4 3.0 3.1 0.0 0.0 7.1 0.3 0.0 2.9 2.0 8.5 0.0 0.2 0.1 0.0 8.2 1.3 0.0 0.7 0.0 0.3 6.8 9.1 0.3 0.2 8.0 6.1 0.1 0.0 6.0 0.0 0.0 17.5 7.5 0.8 0.0 8.4 3.5 0.0 10.4 6.0 1.1 4.2 0.0 0.1 0.7 2.4 0.0 3.4 0.0 2.7 2.4 0.1 8.0 6.7 0.4 5.6 9.4 11.5 5.6 4.7 0.1 0.1 1.3 0.5 0.4 1.8 0.2 1.0 1.0 0.6 1.4 0.2 0.9 2.0 5.7 1.3 0.4 0.3 0.9 0.4 0.7 5.1 10.4 1.0 6.8 6.4 3.4 14.4 3.0 5.1 13.3 MMAB "cblB, CFAP23" ENSG00000139428 "Methylmalonic aciduria (cobalamin deficiency) cblB type" Q96EY8 12 109553737-109573874 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Approved Approved Mitochondria Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favourable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 7.3 26.1 12.7 7.2 12.2 5.2 13.0 7.2 17.2 7.0 12.2 12.6 9.4 12.7 7.7 21.9 14.8 9.8 11.8 18.1 11.6 11.5 13.6 47.9 11.8 13.0 12.4 8.2 14.2 20.2 9.1 11.7 5.3 14.0 15.7 8.3 11.2 15.1 10.6 16.5 8.9 8.5 8.7 15.7 6.7 10.7 7.8 14.8 4.3 16.6 15.7 7.5 6.0 7.5 14.1 9.4 3.8 8.1 8.5 13.9 9.2 13.2 9.0 9.4 7.4 3.8 7.8 4.8 2.9 6.9 4.3 4.6 10.5 12.5 8.5 8.6 3.3 13.9 6.2 23.0 2.0 3.3 25.3 3.5 6.7 17.2 13.7 7.4 3.1 10.5 14.4 9.5 4.2 4.1 11.1 6.5 3.1 30.7 6.7 12.0 11.6 12.9 5.6 3.6 22.1 19.2 12.6 14.6 6.3 6.7 12.4 5.1 25.9 20.9 2.2 3.8 1.5 2.6 4.3 5.1 3.8 9.6 8.2 9.1 10.2 3.8 5.9 0.8 13.5 8.1 10.8 11.1 9.9 10.7 9.4 14.1 13.9 13.1 1.7 8.5 8.0 7.7 4.7 9.2 12.7 12.2 7.2 17.2 11.6 11.5 12.4 8.2 14.0 14.8 MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187519-36272157 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.0;liver: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;hTERT-HME1: 25.1;SiHa: 26.9;SK-MEL-30: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol Mitochondria Cytosol "HPA039412: , HPA047958: " "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavourable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavourable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" 3.7 12.7 0.6 1.6 0.5 0.2 6.4 0.4 0.4 1.4 10.4 0.7 8.0 6.7 1.3 4.6 4.8 1.9 5.8 1.3 0.4 0.5 1.7 36.6 1.8 0.2 0.4 0.1 17.2 3.2 1.1 9.4 11.2 2.2 2.8 1.8 2.1 2.5 7.2 1.3 2.6 33.0 1.0 0.4 0.7 1.7 1.3 0.2 0.0 1.2 2.9 3.5 2.6 1.7 0.4 0.3 1.9 0.3 1.1 0.3 0.1 6.8 2.3 0.1 0.0 2.2 2.8 1.4 4.0 2.2 1.9 5.0 1.5 2.1 0.0 1.2 6.5 4.2 1.4 6.3 2.7 1.1 1.1 0.1 6.8 5.6 7.5 0.0 1.9 4.4 20.4 7.6 25.1 0.3 2.3 0.0 3.1 1.7 0.0 0.0 0.4 2.0 0.0 0.0 0.0 2.7 9.0 0.0 0.6 26.9 1.7 18.7 1.2 0.1 1.3 1.5 1.9 3.3 0.6 0.0 0.0 0.0 3.9 0.0 0.6 1.7 0.3 0.3 0.3 0.2 0.2 0.3 0.2 0.3 0.1 0.4 0.2 0.3 1.9 1.1 0.2 0.3 0.1 0.1 0.6 0.5 0.4 0.4 0.4 0.5 0.4 0.1 2.2 0.2 MOCS2 MOCO1 ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favourable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 18.1 34.6 41.5 9.8 38.0 4.0 19.6 21.7 41.8 16.0 17.1 20.7 10.4 17.6 14.8 28.2 17.0 12.9 15.9 39.9 36.7 32.1 49.7 52.0 13.1 11.4 30.0 22.4 21.2 18.4 30.4 23.3 16.2 28.7 18.6 14.9 17.2 21.2 20.8 38.3 8.9 17.6 16.1 27.1 10.7 16.6 11.0 20.0 8.2 31.5 19.4 11.2 16.9 15.4 16.9 12.5 6.3 10.9 17.3 25.8 12.9 20.1 16.6 12.0 28.6 24.6 22.7 15.2 24.8 26.1 22.2 26.3 22.6 15.2 20.7 37.5 19.6 12.3 24.0 25.5 35.0 5.2 23.4 15.9 16.3 20.4 25.3 17.1 11.9 18.0 12.8 25.2 22.4 23.8 15.3 11.3 36.9 30.0 18.5 9.8 10.6 34.5 9.3 25.8 18.8 38.4 15.4 8.9 10.3 18.1 14.8 18.6 28.6 4.4 15.2 21.3 22.0 18.9 31.9 13.2 19.6 23.4 30.5 4.9 32.8 5.2 9.2 6.3 16.9 10.9 20.2 16.5 19.0 19.2 12.5 16.9 25.8 22.2 1.7 17.3 9.8 11.4 18.3 12.9 41.5 38.0 21.7 41.8 36.7 32.1 30.0 22.4 28.7 20.0 MOCS3 "dJ914P20.3, UBA4" ENSG00000124217 "Molybdenum cofactor synthesis 3" O95396 20 50958826-50963931 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis, tRNA processing" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027556 Uncertain "HPA027556: " "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" "unprognostic (3.16e-1)" "prognostic unfavourable (5.82e-4)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "prognostic unfavourable (1.39e-4)" "unprognostic (3.76e-1)" "unprognostic (3.19e-1)" "unprognostic (1.33e-2)" "unprognostic (8.67e-3)" "unprognostic (4.90e-2)" "prognostic favourable (7.55e-4)" "unprognostic (8.39e-2)" "unprognostic (8.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" 5.3 9.2 5.4 6.4 9.0 3.4 6.6 5.6 13.7 7.4 6.7 7.0 8.8 7.1 9.0 9.9 9.8 9.3 8.7 7.2 5.3 6.6 6.9 9.8 5.3 10.5 4.7 6.3 10.2 7.9 6.2 7.7 11.0 6.1 7.6 5.8 7.2 7.7 6.8 10.3 8.4 8.1 6.0 3.7 9.5 7.3 19.4 3.3 12.1 9.7 8.8 8.8 8.3 5.7 8.9 8.6 6.7 9.7 7.5 11.2 6.5 3.4 5.8 3.6 5.0 5.1 4.2 6.6 4.0 4.3 10.1 4.4 12.4 5.0 5.1 5.3 3.6 9.8 3.7 9.9 6.5 1.8 3.9 4.0 4.8 7.1 5.3 4.0 4.3 4.7 8.4 4.1 4.1 3.4 5.8 3.1 3.7 5.5 6.5 4.8 5.3 10.0 2.6 5.6 4.4 4.0 5.3 5.2 6.1 6.2 20.2 6.4 8.4 7.7 4.1 7.7 4.4 4.1 4.3 7.7 6.9 2.2 6.9 2.4 3.2 4.9 7.5 6.7 6.4 6.8 8.1 8.9 6.6 7.0 8.6 7.0 11.2 8.7 4.1 7.5 9.7 4.8 10.0 6.5 5.4 9.0 5.6 13.7 5.3 6.6 4.7 6.3 6.1 3.3 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671786-222709930 "Enzymes, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "gallbladder: 40.9" "Cell line enhanced" "Detected in single" "Hep G2: 1.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 7 "dendritic cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA049944 Uncertain "HPA049944: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 2.3 0.1 0.6 0.1 0.5 0.1 1.3 0.2 0.9 0.3 0.6 0.5 0.2 0.0 1.0 1.1 0.5 0.1 40.9 0.8 0.5 0.2 5.7 7.6 1.1 0.3 0.2 0.9 0.1 1.5 2.3 0.4 0.0 0.9 0.2 0.1 0.0 1.4 2.6 0.5 1.6 0.2 0.1 0.3 0.1 1.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 3.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.5 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.6 0.5 0.2 0.9 0.5 0.2 0.2 0.9 0.9 0.0 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717819-75732958 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 90.2;liver: 40.5" "Group enriched" "Detected in some" 7 "Hep G2: 8.4;RPMI-8226: 5.6" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028834 Uncertain "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.1 0.0 0.1 4.8 0.1 0.0 2.1 0.1 0.1 0.2 34.0 0.1 1.4 22.3 0.1 0.1 0.2 0.0 2.6 0.1 0.1 0.0 0.2 40.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 7.0 0.1 0.4 2.2 0.4 0.9 90.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 5.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 MOGAT3 "DC7, DGAT2L2, MGAT3" ENSG00000106384 "Monoacylglycerol O-acyltransferase 3" Q86VF5 7 101195007-101201021 "Enzymes, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 61.6;liver: 16.0" "Group enriched" "Detected in some" 6 "CACO-2: 4.7;Hep G2: 15.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.0;liver cancer: 11.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "neutrophil: 5.3" "Low lineage specificity" "Detected in many" HPA011940 Approved Approved Centrosome Centrosome "HPA011940: AB_1854057" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (7.14e-2)" "unprognostic (6.11e-2)" "unprognostic (3.20e-1)" "unprognostic (9.54e-3)" "unprognostic (9.36e-2)" "unprognostic (3.08e-1)" "unprognostic (1.05e-3)" "unprognostic (1.87e-1)" "unprognostic (1.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.59e-2)" 0.2 0.1 0.2 2.6 0.2 0.4 0.2 0.2 0.2 0.2 17.3 0.2 0.2 19.7 0.2 0.5 0.2 0.1 0.2 0.2 0.2 0.1 0.9 16.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 7.1 0.2 0.2 0.2 0.2 0.1 61.6 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.7 1.2 5.3 0.9 1.9 1.2 0.3 0.6 0.2 0.2 0.5 0.0 0.1 0.4 0.6 0.0 0.0 0.0 4.7 1.1 0.3 0.6 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.6 0.6 15.8 0.2 0.5 0.6 0.1 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.3 0.3 0.5 0.2 0.6 0.3 0.1 0.4 0.7 0.6 0.3 0.3 0.3 0.6 0.1 0.3 0.3 0.8 0.9 0.2 1.0 0.5 0.4 0.2 0.1 1.7 0.6 1.4 2.2 0.9 1.1 1.0 0.7 0.7 1.0 0.8 0.7 0.5 1.7 0.9 1.2 5.3 1.9 0.6 1.2 0.5 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305200 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 28.0;hTEC/SVTERT24-B: 71.2;NB-4: 88.6;U-138 MG: 37.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027292 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 5.9 6.8 12.9 2.7 17.3 3.7 7.8 9.7 15.9 7.6 3.6 8.7 6.2 4.7 7.6 10.2 3.9 26.4 6.4 8.3 13.5 10.2 7.7 3.6 6.1 2.5 6.0 13.7 12.4 8.6 9.4 22.1 3.6 16.6 5.1 3.0 15.2 6.1 5.4 1.9 8.6 4.1 5.9 6.2 3.8 11.7 45.0 6.2 0.4 11.7 2.3 2.2 6.2 3.9 0.7 3.9 0.9 1.1 10.6 2.4 1.3 3.3 3.0 0.4 1.7 0.7 2.5 0.7 6.8 2.0 9.9 11.9 0.2 8.3 2.5 0.5 1.3 0.7 0.6 3.5 28.0 2.8 2.5 0.6 0.3 2.2 3.0 0.2 3.3 2.1 0.9 71.2 6.6 0.3 0.6 0.1 6.4 2.2 0.2 88.6 0.1 7.2 0.4 0.1 0.0 4.0 0.1 1.1 0.7 1.2 0.4 19.2 2.0 0.2 0.2 37.6 1.9 1.4 2.1 0.2 0.4 0.2 7.5 0.2 17.0 0.0 1.1 0.0 0.7 0.7 1.2 0.0 0.5 1.9 3.9 0.7 1.1 2.4 0.9 10.6 0.1 0.0 0.0 1.3 12.9 17.3 9.7 15.9 13.5 10.2 6.0 13.7 16.6 6.2 MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (3.28e-1)" 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029822 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 106.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol 2800000 Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favourable (5.89e-4)" 8.7 7.2 4.5 6.8 6.4 10.5 22.7 2.6 5.4 8.8 39.1 8.0 2.8 36.8 6.1 3.0 19.8 4.3 15.3 14.1 4.6 2.3 14.1 106.2 10.3 5.4 8.8 3.8 12.6 20.7 0.7 2.7 4.2 5.6 6.6 5.7 3.8 13.4 3.9 11.5 15.9 33.7 4.8 4.8 4.1 12.8 24.9 7.1 2.1 6.3 6.2 5.1 8.7 11.6 9.6 37.1 18.5 26.5 28.8 16.1 12.5 14.1 16.7 8.2 16.9 9.6 6.0 13.0 7.7 6.9 8.4 11.4 15.9 6.3 22.3 11.2 5.5 9.9 7.1 11.2 1.2 13.4 39.7 8.6 7.3 37.4 30.6 9.2 12.1 10.5 21.9 5.5 5.1 17.0 15.3 6.5 2.3 11.0 0.8 31.5 15.4 17.4 23.9 9.7 16.6 8.5 4.6 4.2 31.6 5.1 8.1 14.7 8.7 15.0 13.1 7.3 20.7 8.0 5.2 11.4 5.3 6.7 2.6 11.3 3.7 15.3 26.5 18.5 11.8 9.4 16.1 9.6 7.7 9.9 37.1 9.6 1.1 4.1 7.9 28.8 4.3 6.0 15.2 12.5 4.5 6.4 2.6 5.4 4.6 2.3 8.8 3.8 5.6 7.1 MST1R "CD136, CDw136, PTK8, RON" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.7;intestine: 34.3;skin 1: 28.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.3;HaCaT: 19.5;HBEC3-KT: 21.2;hTCEpi: 29.8;RT4: 22.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favourable (2.33e-5)" 1.7 0.1 0.4 7.5 0.6 0.0 2.4 0.5 0.7 1.8 20.5 0.7 2.0 11.2 1.2 1.3 6.1 0.6 27.7 0.9 0.5 0.1 1.4 0.4 5.0 1.1 0.4 0.6 0.5 4.1 0.0 1.3 0.8 0.9 1.7 9.7 2.5 2.1 0.4 0.5 28.7 34.3 0.7 0.4 0.6 19.1 1.9 0.4 7.7 1.3 6.0 4.5 4.3 3.5 0.2 0.0 0.0 0.0 0.6 2.1 0.0 12.7 4.9 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.2 35.3 0.5 3.1 0.2 19.5 0.0 21.2 0.0 0.3 0.3 0.0 8.4 0.3 0.3 0.0 0.4 0.1 29.8 0.1 4.2 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.1 10.3 0.8 0.0 0.3 13.0 22.8 0.3 0.0 3.6 8.2 0.0 6.5 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.4 0.6 0.5 0.7 0.5 0.1 0.4 0.6 0.9 0.4 MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802543-21937651 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046915 Approved Cytosol 3100000 Cytosol "HPA046915: " "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.21e-1)" "unprognostic (2.58e-3)" "unprognostic (2.78e-1)" "unprognostic (6.16e-2)" "prognostic unfavourable (4.68e-4)" "unprognostic (9.47e-2)" "unprognostic (2.03e-1)" "unprognostic (8.63e-2)" "unprognostic (4.76e-3)" "unprognostic (4.27e-2)" "unprognostic (6.28e-3)" "unprognostic (2.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" 17.0 12.6 7.8 12.6 10.4 8.4 13.9 4.6 10.2 17.3 14.5 12.8 13.4 8.0 21.2 11.6 19.6 12.2 16.9 11.4 7.9 7.7 13.0 17.5 11.4 13.0 12.0 6.2 20.5 17.2 17.6 14.4 17.5 12.3 17.0 13.1 14.3 14.6 15.9 10.8 11.8 10.3 19.9 14.3 17.9 11.7 7.9 10.1 19.1 11.7 14.3 16.2 19.7 17.2 9.3 8.4 1.4 6.9 8.5 8.2 3.5 14.2 2.2 11.6 9.7 9.5 9.8 13.0 20.8 10.2 10.6 12.2 9.8 6.7 7.1 6.5 9.9 6.6 11.8 29.4 18.0 0.1 9.7 0.1 27.0 12.9 9.3 11.4 12.7 11.8 0.0 19.5 21.4 11.0 0.1 9.6 11.1 2.0 13.0 0.3 13.5 17.4 0.1 8.8 12.5 9.1 0.1 6.6 7.5 6.8 8.0 10.3 5.2 0.2 11.9 0.1 7.5 0.1 16.6 6.4 11.3 14.9 0.1 11.3 6.1 1.4 6.9 0.3 5.0 5.4 8.2 7.7 7.2 5.6 8.4 9.3 6.5 5.9 1.0 8.5 3.4 8.0 4.1 3.5 7.8 10.4 4.6 10.2 7.9 7.7 12.0 6.2 12.3 10.1 MTFMT FMT1 ENSG00000103707 "Mitochondrial methionyl-tRNA formyltransferase" Q96DP5 15 65001512-65029639 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040710 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040710: AB_10794879" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (9.28e-3)" "unprognostic (4.35e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (6.63e-2)" "unprognostic (2.02e-1)" "unprognostic (6.95e-2)" "unprognostic (2.18e-2)" "unprognostic (2.41e-2)" "unprognostic (1.78e-1)" "prognostic favourable (3.31e-8)" "unprognostic (2.75e-2)" "unprognostic (4.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.85e-2)" 8.7 10.2 7.9 10.0 11.5 11.6 7.5 13.5 12.7 9.5 12.7 6.8 8.0 9.7 11.8 10.6 9.5 10.9 9.7 13.8 8.0 7.8 12.8 13.4 8.4 8.6 6.8 9.4 14.0 5.9 7.3 9.3 7.5 10.3 10.8 10.8 12.2 8.7 9.8 13.3 11.6 13.9 12.0 5.7 9.2 8.7 7.2 5.2 9.2 11.7 4.6 8.8 12.0 9.1 5.0 9.6 16.9 3.6 4.6 5.9 1.9 2.6 3.6 3.5 6.1 5.0 3.5 3.1 2.4 4.3 3.2 3.0 2.2 3.0 9.1 3.3 4.4 7.7 6.5 4.3 3.1 3.5 4.8 3.9 3.4 2.5 5.9 5.3 1.2 5.1 5.4 1.7 3.8 2.9 4.1 4.4 4.8 3.6 4.2 5.6 4.8 6.2 3.9 5.1 4.2 5.2 3.1 3.6 3.6 5.8 5.4 4.4 3.3 3.8 5.3 3.8 3.9 4.4 4.8 3.7 5.4 3.6 3.3 8.6 3.9 3.1 3.6 2.4 4.9 2.9 4.9 4.7 4.9 5.2 5.6 5.0 5.5 5.9 16.9 4.6 2.0 9.6 4.9 1.9 7.9 11.5 13.5 12.7 8.0 7.8 6.8 9.4 10.3 5.2 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262507 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "CAB069425: , HPA071227: " "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favourable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 11.3 13.9 18.7 13.0 22.5 12.3 14.9 25.2 25.2 11.3 14.5 18.2 10.4 11.2 13.8 23.6 13.1 10.5 15.7 14.2 14.5 13.6 15.8 19.4 10.8 14.3 14.0 14.4 10.7 16.6 26.5 16.0 12.5 15.5 15.2 17.1 14.4 14.2 15.2 24.6 16.5 13.6 15.2 10.4 15.4 13.1 38.6 13.1 16.6 13.2 9.9 15.7 11.7 10.2 3.9 4.0 3.0 6.4 2.6 5.6 2.3 15.2 13.8 18.7 14.1 22.6 10.8 9.3 12.9 12.4 17.2 17.0 14.2 14.1 16.9 11.1 15.2 18.2 25.2 19.7 22.3 13.5 18.4 22.5 28.6 17.9 14.2 21.9 16.8 13.8 15.0 24.6 25.0 21.8 25.1 14.6 12.0 17.4 15.1 16.7 14.1 13.1 15.2 22.0 11.3 15.2 13.8 18.9 13.8 27.6 14.9 16.9 12.1 13.0 23.2 15.1 13.7 11.5 17.2 14.4 13.4 33.3 10.9 23.7 15.8 0.7 2.9 3.0 5.2 6.4 4.3 3.9 3.0 2.7 4.0 3.4 3.6 3.1 2.0 2.6 3.3 3.1 5.6 2.3 18.7 22.5 25.2 25.2 14.5 13.6 14.0 14.4 15.5 13.1 MTPAP "FLJ10486, mtPAP, PAPD1, SPAX4" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Mitochondria Mitochondria "HPA038620: AB_10673015, HPA058232: " "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" 10.9 12.7 9.9 10.2 12.4 32.8 11.1 12.4 16.1 9.6 9.9 7.3 6.5 11.0 10.4 7.0 12.6 9.5 7.6 11.5 7.8 7.2 10.6 11.1 9.4 10.5 11.9 13.0 11.4 18.9 9.5 7.2 10.0 11.4 8.0 12.0 8.2 10.7 10.2 22.3 13.1 10.0 14.3 9.0 9.3 9.7 10.6 8.3 6.7 11.0 12.4 10.5 11.7 9.1 15.6 22.9 18.4 24.4 16.9 17.1 8.3 14.2 14.2 9.0 13.1 8.9 8.4 11.7 9.9 3.5 10.1 10.6 15.0 20.0 20.3 7.1 6.5 16.8 17.4 11.5 12.4 10.2 13.6 20.6 13.4 15.1 9.3 13.4 16.2 8.2 10.8 11.3 6.8 11.0 22.2 16.0 7.6 11.9 16.1 11.9 6.1 7.7 16.3 16.0 18.9 9.3 9.5 14.9 12.0 9.0 9.4 13.8 9.0 8.7 10.5 10.7 13.8 14.9 11.0 3.6 8.6 27.8 9.2 24.7 3.7 16.4 18.5 18.4 16.2 24.4 17.1 15.6 15.4 15.6 22.9 13.1 16.7 16.8 3.0 16.9 18.1 12.0 15.5 8.3 9.9 12.4 12.4 16.1 7.8 7.2 11.9 13.0 11.4 8.3 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795281-236903981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol Cytosol "HPA044474: AB_10966696, HPA054915: " "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavourable (5.75e-4)" "unprognostic (8.10e-2)" 14.5 11.4 9.9 13.2 13.5 7.6 13.6 14.8 14.4 16.9 16.4 16.2 16.0 7.5 18.1 27.3 10.4 18.4 16.3 21.9 9.4 9.8 21.2 9.5 11.7 14.3 12.6 12.8 24.7 20.8 27.4 12.4 17.5 13.0 14.0 8.9 17.7 11.1 17.3 27.0 15.4 11.7 23.3 12.1 13.9 14.9 20.1 12.1 20.8 22.4 11.1 13.2 18.4 14.4 3.3 1.6 3.0 2.0 2.3 5.8 2.1 9.9 6.7 8.2 6.8 15.3 14.1 9.7 8.7 7.8 9.6 10.0 6.3 7.6 22.1 8.1 9.8 6.9 10.6 7.8 11.5 10.2 9.1 13.0 8.9 11.6 10.3 20.6 8.1 20.1 4.9 12.7 12.2 12.7 18.7 10.4 8.0 6.9 10.7 6.6 11.0 3.6 11.7 14.6 14.2 6.9 11.5 6.7 18.7 9.8 7.2 8.8 10.2 8.4 16.4 15.9 6.1 12.2 11.2 22.6 7.0 12.9 10.3 13.0 15.6 2.7 1.6 3.0 3.2 2.0 5.8 2.7 4.2 4.5 1.5 3.3 5.0 4.0 0.1 2.3 1.5 1.6 2.9 2.1 9.9 13.5 14.8 14.4 9.4 9.8 12.6 12.8 13.0 12.1 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508161 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favourable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 13.3 15.9 10.3 12.9 12.3 20.6 20.4 9.2 22.2 13.1 15.8 19.0 8.0 11.6 18.2 10.7 17.2 17.0 18.5 26.2 11.7 12.5 20.5 20.1 16.3 12.1 16.8 9.5 17.5 26.8 21.9 13.0 21.6 17.6 13.9 13.3 14.3 15.3 18.1 26.7 17.4 19.5 17.0 11.7 13.6 15.2 14.1 11.6 18.5 15.1 14.6 14.0 16.3 13.6 23.2 26.0 31.9 30.4 25.2 32.1 27.5 16.9 16.4 9.5 19.6 20.6 11.6 10.3 16.9 20.2 21.0 20.3 10.1 28.2 12.8 18.9 23.8 25.9 17.0 24.4 15.3 12.7 13.5 9.8 11.1 14.6 24.3 13.4 16.8 18.9 32.2 21.5 22.4 13.7 12.7 15.6 22.8 8.6 8.0 9.0 9.7 15.7 7.9 11.9 16.5 24.7 9.5 9.7 14.3 15.1 16.2 20.7 11.4 12.9 15.4 20.5 11.8 17.8 15.1 18.3 15.9 13.8 16.1 18.2 19.0 26.3 26.5 31.9 30.9 30.4 32.1 23.2 23.6 31.4 26.0 21.5 27.1 26.3 24.0 25.2 25.4 20.1 32.1 27.5 10.3 12.3 9.2 22.2 11.7 12.5 16.8 9.5 17.6 11.6 MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668771-110801620 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 50.0" "Group enriched" "Detected in some" 15 "LHCN-M2: 19.3;RH-30: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Not detected" "Not detected" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (5.39e-2)" "unprognostic (3.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (6.03e-5)" "unprognostic (4.58e-2)" "unprognostic (1.62e-1)" "unprognostic (9.67e-2)" "unprognostic (5.11e-2)" 7.5 0.3 0.6 5.8 0.7 0.0 0.2 0.1 0.2 0.3 6.8 0.0 0.0 2.3 0.2 4.0 3.8 0.1 2.1 3.2 0.9 0.7 0.2 0.5 4.2 0.9 0.2 0.1 0.3 0.3 0.0 0.2 0.6 0.3 1.9 5.3 0.0 0.4 0.0 50.0 0.3 5.0 3.0 0.3 0.2 2.6 5.9 0.0 0.0 0.3 1.4 3.9 3.6 2.9 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.4 0.2 0.0 19.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.2 0.9 0.7 0.2 0.1 0.3 0.0 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598117 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 4.7 14.3 6.8 5.9 11.7 6.8 11.2 6.3 13.1 7.1 7.8 16.7 5.1 11.5 4.2 9.5 23.0 5.1 5.3 6.7 7.8 9.0 16.5 33.1 8.7 4.9 12.5 8.3 8.5 9.3 7.0 6.5 5.5 22.5 9.0 6.3 6.4 8.1 5.8 6.3 19.5 6.9 3.7 18.0 3.8 6.1 17.5 10.5 2.8 11.9 8.5 8.8 5.5 9.9 11.5 7.4 3.4 5.9 8.3 12.2 5.4 12.3 10.4 12.7 6.3 4.1 10.1 6.8 4.5 8.4 11.8 12.9 15.0 15.1 8.7 3.5 4.5 15.1 13.5 21.2 5.7 8.5 9.6 4.6 7.1 22.4 12.7 4.9 5.9 11.0 17.9 21.4 5.8 8.0 8.0 8.3 5.3 15.6 5.0 15.7 10.7 16.1 4.6 9.7 17.0 27.2 18.4 11.8 10.2 8.8 25.1 6.2 23.1 8.6 7.0 5.4 7.1 5.2 5.7 7.0 9.2 12.8 6.5 12.7 7.4 0.7 5.9 3.4 12.2 5.8 9.9 8.4 7.4 11.6 7.4 11.5 11.7 8.3 1.7 8.3 3.7 6.2 6.2 5.4 6.8 11.7 6.3 13.1 7.8 9.0 12.5 8.3 22.5 10.5 MYCBP2 "FLJ10106, KIAA0916, PAM" ENSG00000005810 "MYC binding protein 2, E3 ubiquitin protein ligase" O75592 13 77044655-77327050 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA058807: " "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favourable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 28.0 13.4 31.0 26.1 28.8 24.1 22.4 31.3 32.7 15.5 10.9 8.1 11.5 8.0 16.2 26.7 18.9 11.7 11.1 13.5 24.1 18.6 12.3 13.2 12.4 29.8 15.3 31.1 22.8 12.6 14.5 17.2 9.6 20.0 17.9 11.5 9.6 12.9 12.4 13.7 57.6 13.6 13.2 14.0 24.1 10.3 14.1 16.2 18.6 11.6 12.6 30.7 13.3 34.0 8.3 4.6 3.3 3.7 4.2 7.3 2.5 7.7 3.9 4.8 5.2 24.0 10.7 2.8 4.9 7.3 4.3 5.5 3.5 4.0 22.1 3.1 9.6 7.1 8.2 9.0 5.8 8.7 8.2 18.7 8.0 7.2 8.2 39.2 6.6 12.0 7.5 3.9 7.9 9.7 3.9 7.0 7.6 4.6 10.7 26.5 2.5 5.0 12.2 4.9 5.3 7.2 7.7 7.5 3.5 5.9 8.6 4.4 3.2 30.1 12.8 4.1 3.4 2.7 4.7 7.6 5.2 15.7 8.3 32.3 4.1 2.0 3.5 3.2 5.8 3.7 5.1 7.9 6.5 5.0 3.2 8.3 7.3 5.8 3.3 4.2 2.5 4.6 7.3 2.5 31.0 28.8 31.3 32.7 24.1 18.6 15.3 31.1 20.0 16.2 MYLIP "IDOL, MIR" ENSG00000007944 "Myosin regulatory light chain interacting protein" Q8WY64 6 16129125-16148248 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 84.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.54e-1)" "unprognostic (4.84e-3)" "unprognostic (2.79e-1)" "unprognostic (9.65e-3)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-2)" "prognostic favourable (6.44e-6)" "unprognostic (2.75e-2)" "unprognostic (2.67e-2)" "unprognostic (5.44e-3)" "unprognostic (1.03e-2)" "prognostic favourable (3.67e-4)" "unprognostic (1.42e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "prognostic favourable (4.11e-5)" 23.4 12.5 7.3 10.3 10.6 44.2 19.5 5.4 11.4 28.5 14.4 18.9 16.4 7.5 31.8 16.1 12.1 22.2 19.1 9.0 8.6 6.1 13.1 3.5 19.0 19.4 12.9 8.8 22.3 10.5 9.8 6.1 84.0 7.4 20.1 9.7 20.2 16.2 20.9 20.6 16.7 15.7 18.0 7.0 23.5 14.8 15.2 12.2 8.8 39.1 10.9 15.7 19.0 33.7 4.9 1.4 14.2 2.3 3.2 8.4 1.5 1.9 4.0 1.6 2.0 17.1 4.6 4.4 1.4 3.4 3.4 7.5 11.4 2.1 9.1 7.3 2.2 5.1 8.0 2.5 2.9 3.3 8.3 6.1 4.3 2.1 2.5 4.2 6.1 7.3 3.3 1.7 1.4 7.9 17.6 10.8 1.3 7.6 0.1 20.6 4.8 3.7 2.0 7.8 33.5 3.7 24.3 8.5 3.6 1.7 18.6 9.4 3.4 10.3 2.3 1.6 3.9 1.2 3.5 10.0 4.4 4.8 1.0 12.1 5.4 8.5 2.3 11.1 8.4 2.2 7.3 4.9 5.3 5.9 1.4 4.9 5.9 5.4 14.2 3.2 2.0 0.7 3.2 1.5 7.3 10.6 5.4 11.4 8.6 6.1 12.9 8.8 7.4 12.2 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell line enhanced" "Detected in many" "BJ: 36.5;BJ hTERT+: 55.2;fHDF/TERT166: 45.0;HBF TERT88: 29.0;RPTEC TERT1: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: " "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavourable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.1 1.3 2.1 0.4 0.9 36.5 55.2 23.6 17.0 1.6 1.4 0.1 8.2 45.0 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 11.0 0.1 1.9 6.8 0.7 4.6 6.9 1.8 0.2 0.1 17.5 0.3 0.0 0.5 2.2 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell line enhanced" "Detected in some" "Karpas-707: 5.2;RH-30: 13.2;RPMI-8226: 10.7" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA059704: , HPA059890: " "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favourable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.0 0.2 5.2 0.1 0.8 0.7 0.4 0.6 0.4 0.7 13.2 10.7 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 2.6 0.2 1.0 0.6 2.9 0.1 0.9 0.2 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell line enhanced" "Detected in some" "BEWO: 9.5;HEL: 28.5;K-562: 4.4;SK-BR-3: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in some" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA073447: " "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 1.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell line enriched" "Detected in some" 6 "HEL: 12.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.1 0.6 1.1 1.0 1.2 0.6 0.7 1.5 0.5 0.4 0.5 1.0 1.0 1.6 0.8 1.9 0.2 0.4 0.7 0.2 0.6 12.4 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.5 0.1 0.1 0.3 0.5 0.1 1.3 0.2 0.0 0.9 0.0 0.0 0.8 0.3 1.0 0.6 0.3 0.2 0.5 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.2 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934071-26212536 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.1;testis: 12.5" "Cell line enhanced" "Detected in some" "AF22: 2.3;CAPAN-2: 2.2;HEK 293: 2.6;SCLC-21H: 2.4;U-2 OS: 4.3;U-698: 10.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 5.0;cerebral cortex: 1.9;hypothalamus: 1.3;pons and medulla: 5.4" "Cell type enriched" "Detected in single" 12 "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 12 "B-cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048951, HPA051893" Approved Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA048951: , HPA051893: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.8 0.7 0.4 0.3 5.0 0.5 1.5 0.3 1.9 2.1 0.6 0.1 0.7 0.4 0.3 3.2 0.9 1.1 0.3 0.3 0.5 1.3 0.9 0.2 1.0 0.3 0.2 0.0 0.5 2.1 0.2 8.1 0.2 5.4 0.5 1.1 3.8 0.2 0.6 0.3 2.2 0.6 1.0 0.4 0.3 0.9 12.5 0.8 0.0 1.3 1.4 0.9 0.5 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.0 0.0 1.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.3 1.9 0.5 1.3 0.2 0.0 5.4 0.8 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.0;parathyroid gland: 12.6;retina: 21.6" "Group enriched" "Detected in some" 10 "HDLM-2: 11.0;HEL: 10.1;RT4: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "gdT-cell: 1.4;naive CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.4" "Region enriched" "Detected in single" 5 "basal ganglia: 4.7" "Not detected" "Not detected" HPA045483 Approved "HPA045483: " "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.2 0.2 0.3 0.0 0.3 0.0 0.2 0.2 0.3 0.6 0.2 0.0 4.6 0.0 0.3 20.0 0.3 0.5 0.0 0.3 0.3 0.5 8.5 0.2 0.3 0.5 0.3 0.3 0.4 2.2 12.6 1.0 0.0 0.3 0.3 0.0 21.6 1.4 1.1 0.2 0.5 0.2 0.5 0.2 0.3 0.2 4.2 0.0 0.0 2.2 0.0 0.8 4.4 0.3 0.1 0.3 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.3 0.3 0.0 NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N(alpha)-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929242-153935223 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB006269: AB_425759, HPA030711: " "unprognostic (7.57e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (1.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (9.01e-2)" "unprognostic (9.63e-2)" "prognostic unfavourable (3.29e-8)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (7.48e-3)" 18.9 21.2 17.7 20.3 14.0 12.5 31.8 15.5 20.8 12.4 15.3 8.1 19.2 16.7 17.2 17.6 19.7 16.5 17.6 26.4 15.0 14.2 16.3 18.6 20.7 30.0 15.0 18.0 14.1 33.3 12.3 12.0 13.7 17.5 13.6 11.7 9.3 19.0 17.9 57.8 14.1 14.7 21.7 14.7 14.9 17.7 7.1 11.8 11.4 12.2 25.3 16.3 17.1 22.1 33.7 34.8 35.0 31.9 27.6 44.8 29.0 31.8 33.6 6.3 20.6 9.1 9.5 18.0 11.2 6.6 15.3 13.5 21.8 10.1 24.2 37.4 9.3 15.3 13.3 13.5 6.0 10.1 61.9 8.7 23.5 21.9 12.4 16.9 19.3 7.2 15.2 14.3 14.8 17.3 17.4 10.3 10.1 41.9 27.0 25.3 10.6 46.6 21.5 16.4 26.6 11.2 14.7 13.6 16.4 4.4 17.7 26.5 9.5 14.1 10.0 6.4 22.1 22.3 34.0 21.8 24.3 45.5 8.7 21.9 18.7 12.0 24.2 35.0 29.0 28.0 38.0 33.7 31.2 31.7 31.6 32.6 18.7 28.0 22.6 27.6 31.9 34.8 44.8 29.0 17.7 14.0 15.5 20.8 15.0 14.2 15.0 18.0 17.5 11.8 NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N(alpha)-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326050 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 166 "placenta: 32.1;testis: 30.5" "Group enriched" "Detected in some" 6 "K-562: 9.1;U-266/70: 26.0;U-266/84: 8.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA035922: AB_10673490" "unprognostic (7.37e-2)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 32.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 30.5 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 26.0 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N(alpha)-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017116-20033655 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol Cytosol "HPA063344: " "unprognostic (2.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (6.18e-2)" "unprognostic (9.30e-2)" "unprognostic (3.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" 15.9 20.0 14.2 10.0 21.4 17.4 23.2 15.5 34.1 17.3 12.7 12.0 22.7 9.7 20.5 17.7 58.4 15.8 12.3 24.1 14.7 14.1 24.6 25.0 15.7 19.0 13.1 18.3 12.9 43.2 24.8 20.0 18.5 19.4 14.4 12.2 11.2 22.0 20.6 35.2 15.6 11.0 17.3 13.1 11.0 14.5 43.7 10.2 9.5 23.6 37.5 22.1 14.0 23.7 18.6 28.3 20.4 27.5 17.7 25.8 26.4 40.2 24.5 8.8 13.8 18.7 19.7 13.3 29.8 20.4 26.9 25.2 12.5 29.3 21.9 16.2 20.1 32.0 15.1 47.8 21.9 9.8 16.4 16.4 6.5 18.7 26.8 17.3 12.2 22.4 31.5 27.2 27.5 23.0 26.5 22.6 23.4 31.6 24.3 18.0 6.9 40.0 13.4 34.8 29.0 26.4 9.3 16.8 11.4 18.0 50.9 24.9 31.4 27.9 25.0 22.3 13.1 26.8 27.3 24.6 30.7 23.6 13.6 15.2 15.9 8.0 27.5 20.4 17.6 27.5 25.8 18.6 20.5 20.2 28.3 16.5 19.9 22.0 3.6 17.7 23.2 22.9 20.8 26.4 14.2 21.4 15.5 34.1 14.7 14.1 13.1 18.3 19.4 10.2 NAA30 "C14orf35, FLJ35355, MAK3, Mak3p, NAT12" ENSG00000139977 "N(alpha)-acetyltransferase 30, NatC catalytic subunit" Q147X3 14 57390544-57415917 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057824 Uncertain Supported Cytosol Cytosol "HPA057824: " "unprognostic (5.13e-2)" "unprognostic (7.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (6.31e-2)" "unprognostic (1.84e-2)" "unprognostic (5.44e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (5.21e-2)" "prognostic favourable (1.25e-8)" "unprognostic (1.77e-1)" "unprognostic (1.67e-1)" "unprognostic (5.75e-3)" "unprognostic (1.63e-1)" 10.7 10.3 15.8 10.7 18.3 15.0 16.4 18.1 18.9 9.9 15.0 9.2 8.6 11.4 12.1 8.8 13.5 9.1 12.5 18.8 13.9 15.6 14.7 19.1 8.2 9.6 12.9 16.4 18.1 10.5 16.2 13.4 15.4 12.0 12.3 9.6 9.6 10.8 12.8 34.9 10.5 13.5 13.0 9.9 9.8 8.6 21.4 10.1 15.0 12.6 13.6 10.3 12.8 13.7 2.6 1.5 1.7 5.3 5.5 4.2 0.8 13.8 13.3 7.7 12.4 12.9 17.0 12.9 16.3 15.8 12.5 11.4 12.0 10.3 10.2 14.4 13.4 14.7 13.7 10.5 20.8 17.7 7.0 8.2 7.7 10.4 13.5 16.5 9.6 11.5 15.6 11.3 18.9 19.1 8.0 10.2 16.4 16.0 13.7 9.6 8.2 14.9 11.0 22.0 7.9 12.8 12.7 16.5 8.6 13.7 13.6 16.4 17.5 8.6 16.6 19.6 20.5 10.7 10.3 7.5 9.2 12.5 13.0 8.3 13.8 1.7 0.9 0.5 2.9 2.1 3.0 2.3 2.8 4.2 0.8 2.6 3.0 2.8 0.4 5.5 5.3 1.5 3.7 0.8 15.8 18.3 18.1 18.9 13.9 15.6 12.9 16.4 12.0 10.1 NAA40 "FLJ13848, NAT11" ENSG00000110583 "N(alpha)-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957328 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037816 Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA037816: AB_10672289" "unprognostic (3.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-1)" "unprognostic (6.88e-3)" "unprognostic (1.50e-1)" "unprognostic (2.11e-1)" "prognostic unfavourable (1.43e-7)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (7.01e-3)" "unprognostic (6.29e-3)" "unprognostic (3.42e-2)" "unprognostic (6.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.25e-2)" 4.9 12.4 9.8 10.0 11.6 4.1 7.6 16.7 13.5 7.1 7.3 12.2 10.8 9.2 5.0 7.7 9.2 11.2 7.6 13.8 9.8 10.0 10.0 5.1 6.1 10.7 8.3 8.6 4.2 8.9 28.0 22.7 10.5 8.9 6.0 7.9 12.2 9.7 11.3 7.5 4.5 9.8 5.4 7.6 12.5 6.3 19.2 8.9 10.1 10.1 4.1 11.7 8.1 4.9 4.1 5.0 3.5 0.8 6.7 10.1 2.8 10.5 12.4 15.5 8.3 4.4 4.2 9.8 7.8 8.4 19.5 13.8 10.2 13.5 6.5 9.8 7.0 9.6 12.9 5.7 14.5 8.5 8.0 8.9 7.8 11.5 5.8 14.0 7.7 4.4 5.2 12.1 3.3 12.6 15.0 5.0 9.0 8.0 15.0 11.1 14.3 8.3 14.9 13.9 8.3 13.0 8.2 20.5 10.9 12.3 10.8 6.4 17.6 6.3 8.1 10.9 13.2 6.3 6.4 5.9 3.7 11.5 6.5 6.1 8.4 3.3 0.8 3.5 10.1 0.6 3.6 4.1 2.7 4.8 3.6 3.9 1.7 4.1 0.3 6.7 0.3 5.0 0.8 2.8 9.8 11.6 16.7 13.5 9.8 10.0 8.3 8.6 8.9 8.9 NAA50 "FLJ13194, MAK3, NAT13, NAT5, San" ENSG00000121579 "N(alpha)-acetyltransferase 50, NatE catalytic subunit" Q9GZZ1 3 113716460-113746300 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 86.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074489 Approved "HPA074489: " "unprognostic (9.74e-2)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "prognostic unfavourable (2.32e-4)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "prognostic unfavourable (1.51e-5)" "unprognostic (1.62e-3)" "unprognostic (6.82e-2)" "unprognostic (3.43e-1)" "prognostic unfavourable (7.92e-5)" "unprognostic (2.97e-3)" "unprognostic (1.09e-1)" "unprognostic (2.25e-2)" "unprognostic (9.59e-2)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" 23.4 23.6 15.9 18.0 19.8 19.7 25.6 17.1 16.5 14.7 16.2 9.3 12.9 12.7 18.4 13.3 32.6 14.7 13.6 17.0 14.1 10.8 17.6 31.8 17.3 20.7 13.8 13.7 17.8 20.7 18.4 14.1 14.9 15.6 14.5 14.7 10.7 21.6 13.8 86.5 17.7 14.0 16.1 15.7 17.7 16.9 19.0 12.9 22.5 18.3 37.0 23.2 19.9 19.8 32.3 24.7 28.7 22.6 17.4 27.3 26.2 88.9 38.9 21.4 24.9 29.1 23.6 44.7 47.9 27.0 29.6 34.1 55.8 32.1 61.6 29.7 25.4 36.8 37.2 32.8 54.4 12.9 19.0 66.4 29.3 33.5 26.7 69.0 21.6 20.1 25.9 33.1 47.9 26.4 41.7 24.9 30.5 42.1 45.6 15.0 47.9 57.3 47.0 32.8 48.6 22.5 67.9 33.0 19.1 34.7 25.9 34.8 35.9 23.0 24.3 40.9 40.7 17.2 36.0 27.7 45.8 114.3 32.1 38.9 25.1 8.5 22.5 11.9 27.3 22.6 24.3 32.3 20.6 25.5 24.7 20.5 18.2 24.0 28.7 17.4 19.8 14.4 21.9 26.2 15.9 19.8 17.1 16.5 14.1 10.8 13.8 13.7 15.6 12.9 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N(alpha)-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443611-3486963 "Enzymes, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favourable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favourable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 18.5 28.7 24.2 17.9 30.8 26.6 16.2 38.1 40.2 17.1 29.4 29.1 34.0 36.8 24.3 18.6 21.3 21.7 23.7 26.2 25.6 21.3 35.8 40.3 23.6 19.4 21.6 17.7 21.2 41.8 46.4 29.0 27.0 24.4 23.7 21.4 29.1 20.7 31.6 38.9 16.9 42.2 19.9 25.7 28.1 34.8 25.3 19.0 22.8 21.8 21.8 24.1 21.7 22.1 8.5 11.2 34.8 13.2 11.6 13.4 10.0 8.1 32.0 22.7 23.8 18.1 12.4 20.3 15.6 16.6 16.1 14.6 21.9 17.6 16.9 15.9 17.7 19.1 22.4 18.2 15.8 25.5 15.1 20.6 20.2 25.6 19.7 26.4 27.3 15.2 14.1 11.1 21.4 25.9 21.7 24.2 11.4 37.3 16.6 19.4 27.7 9.4 20.8 17.2 25.6 16.7 17.2 12.0 26.0 23.2 25.9 12.3 23.0 18.6 19.1 20.8 17.8 6.7 14.4 20.2 18.7 16.5 6.6 16.3 15.8 19.8 10.5 34.8 11.8 12.3 12.5 8.0 10.8 11.5 11.2 8.5 9.3 10.8 13.2 11.6 13.2 7.8 13.4 10.0 24.2 30.8 38.1 40.2 25.6 21.3 21.6 17.7 24.4 19.0 NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 80.4" "Group enriched" "Detected in many" 7 "granulocytes: 80.4;monocytes: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA048909: , HPA053368: " "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" 24.7 34.3 11.1 19.0 11.9 49.0 25.5 9.9 12.6 12.4 18.2 10.8 14.1 20.3 13.9 14.5 12.5 14.3 17.1 11.9 9.9 7.9 12.7 52.3 17.5 27.0 15.8 8.6 16.9 32.2 8.3 11.9 22.5 10.3 13.7 14.1 13.9 21.4 14.5 10.6 11.7 19.4 14.4 8.3 39.4 22.1 17.3 9.6 10.8 14.0 12.0 19.2 13.7 28.3 1.8 7.2 80.4 24.7 0.5 1.4 10.4 15.1 14.6 13.1 19.2 18.7 13.6 16.9 15.3 13.4 17.5 15.6 15.6 27.9 20.1 11.7 11.3 12.9 14.0 12.1 7.8 19.5 22.3 16.4 22.9 26.9 18.1 23.0 27.7 15.9 11.0 10.8 15.5 16.9 20.1 28.8 13.0 17.4 17.3 20.0 8.9 16.6 22.1 11.2 41.1 15.1 12.6 17.7 13.5 17.1 37.7 15.7 13.0 16.1 16.3 12.8 9.2 13.1 13.7 25.7 11.6 45.0 12.6 25.6 6.6 11.8 21.1 49.5 1.2 24.7 1.4 1.8 0.7 0.9 7.2 1.7 0.5 0.7 80.4 0.5 23.8 5.9 1.0 10.4 11.1 11.9 9.9 12.6 9.9 7.9 15.8 8.6 10.3 9.6 NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192592-36242279 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 128.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced 28000 "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: " "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" 5.7 10.2 13.7 4.1 12.5 4.4 6.8 6.7 13.4 6.6 6.0 13.3 5.9 7.0 5.9 4.1 4.9 6.0 5.5 8.3 14.3 8.5 10.0 128.6 4.0 4.2 11.6 12.0 8.8 12.2 4.8 3.1 7.2 11.6 9.5 6.2 3.9 5.6 7.7 11.1 3.3 5.5 24.8 20.3 3.8 7.6 7.3 11.4 2.5 7.6 3.5 5.1 15.2 5.9 5.1 3.3 9.1 4.2 9.5 3.2 1.7 8.9 5.9 9.0 10.3 13.8 11.8 12.3 8.4 5.6 7.8 5.7 16.5 11.3 32.2 6.3 9.6 6.3 8.4 6.1 10.8 8.9 7.4 8.6 17.4 9.6 10.1 18.7 3.5 12.9 9.5 8.5 12.9 8.1 22.7 11.6 7.7 3.6 17.4 7.2 5.0 8.5 16.9 22.3 6.9 9.9 7.7 4.0 9.2 43.4 13.8 4.5 9.8 16.4 6.1 15.1 8.2 11.3 10.0 10.5 12.7 9.5 6.4 24.3 5.9 9.1 2.0 1.9 2.1 2.0 2.7 2.2 3.2 2.5 3.3 5.1 2.7 2.2 0.1 9.5 4.2 1.5 2.9 1.7 13.7 12.5 6.7 11.4 14.3 8.5 11.6 12.0 11.6 11.4 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079805 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol 690000 Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavourable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favourable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 20.0 17.6 21.8 30.9 24.5 9.8 15.7 13.9 18.8 23.6 15.5 23.7 17.4 11.4 16.4 19.7 67.0 13.7 20.0 14.0 17.6 20.4 16.9 20.2 18.3 30.6 31.1 20.3 15.0 25.8 27.5 21.8 43.9 26.2 15.8 15.8 14.7 49.0 17.8 11.3 29.5 14.6 22.8 21.6 43.4 15.5 24.8 26.7 20.2 13.0 27.2 39.9 24.5 26.1 14.3 53.0 37.4 79.3 8.5 7.1 52.2 18.8 15.3 8.6 8.8 34.5 21.1 33.9 42.1 18.2 28.2 25.7 17.9 9.9 10.5 10.1 29.2 9.1 6.6 12.5 17.5 15.0 5.2 5.9 5.0 11.1 25.9 3.7 15.1 18.9 13.1 30.3 4.7 29.6 2.7 11.9 39.1 17.3 9.3 13.2 9.2 11.9 7.3 24.1 5.4 17.1 33.8 9.0 4.9 12.7 20.1 13.2 10.4 4.7 26.0 33.7 13.1 13.0 14.7 8.3 7.2 6.2 23.0 10.1 18.4 10.3 79.3 31.5 5.4 69.8 5.5 14.3 6.4 5.2 53.0 13.3 5.5 4.5 37.4 8.5 46.6 42.4 7.1 52.2 21.8 24.5 13.9 18.8 17.6 20.4 31.1 20.3 26.2 26.7 NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004546-44009063 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;liver: 30.2" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.3;HHSteC: 6.4;TIME: 7.9;U-87 MG: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA027300: " "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" 0.6 0.6 0.5 0.4 2.4 0.0 1.0 0.7 1.5 0.3 7.2 0.5 5.6 16.4 0.5 2.6 0.9 0.3 0.3 0.9 0.7 1.5 4.4 30.2 2.5 0.2 1.8 0.6 0.5 0.3 3.6 0.4 0.4 1.2 0.8 0.4 0.1 0.9 6.5 0.1 0.6 13.4 0.3 2.0 0.5 0.3 0.4 1.1 0.2 2.9 0.0 0.1 0.8 0.8 1.5 2.0 2.3 2.7 1.0 3.5 1.3 3.4 0.2 0.0 0.5 0.0 6.3 0.1 0.6 0.0 0.2 0.0 2.2 0.8 0.0 1.3 0.0 1.4 0.0 1.2 0.1 0.3 0.8 0.1 0.2 2.6 6.4 0.0 0.0 2.7 0.1 0.2 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.0 0.4 2.6 0.1 0.2 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.0 0.2 0.1 7.9 3.0 0.8 0.2 0.7 0.2 0.2 0.2 11.9 0.1 0.4 1.8 1.4 2.3 3.5 1.5 2.8 1.2 2.2 2.9 2.0 1.5 1.1 1.7 0.8 1.0 2.7 0.3 1.7 1.3 0.5 2.4 0.7 1.5 0.7 1.5 1.8 0.6 1.2 1.1 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248285-106286326 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 18 "neutrophil: 143.5" "Lineage enriched" "Detected in many" 20 "granulocytes: 143.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" 2140000 410000 "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: , HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavourable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavourable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavourable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavourable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 67.3 22.2 8.1 113.6 18.1 110.4 52.6 7.8 12.9 11.6 18.2 2.9 9.5 9.3 9.9 13.5 53.4 27.8 28.1 84.4 13.4 6.3 13.5 92.9 48.9 117.5 10.3 5.2 27.3 18.3 5.5 10.0 23.9 29.2 17.4 10.5 8.2 32.9 14.3 41.0 12.9 14.1 44.9 59.1 41.1 26.4 11.9 7.1 6.2 13.5 40.7 13.2 48.8 26.4 0.8 2.0 143.5 7.3 1.0 1.5 1.3 18.9 12.6 4.6 7.6 19.4 22.6 7.5 6.0 34.0 12.2 21.6 7.4 11.5 15.9 14.4 6.7 15.0 8.4 18.1 26.8 9.4 9.1 6.4 5.4 5.8 72.5 12.4 11.9 21.6 20.7 21.8 25.5 38.8 13.4 60.9 14.5 9.9 12.3 5.2 8.8 10.2 5.9 6.5 34.9 11.6 17.8 9.3 5.1 8.4 18.5 21.4 5.9 3.6 33.0 18.2 14.1 26.1 11.0 42.0 23.8 22.8 108.1 14.1 26.9 8.1 2.3 3.5 0.4 5.6 0.7 0.8 0.5 0.6 2.0 0.7 0.8 0.4 143.5 1.0 7.3 0.8 1.5 1.3 8.1 18.1 7.8 12.9 13.4 6.3 10.3 5.2 29.2 7.1 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056739-98083075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Approved Nucleoplasm 200000 Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favourable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavourable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 17.2 10.1 8.8 20.2 11.4 22.2 16.4 7.0 11.7 20.2 47.6 6.4 17.0 19.4 11.0 15.1 18.6 10.4 25.0 20.9 14.4 12.4 15.0 49.6 17.1 20.1 11.5 10.6 14.1 59.2 6.1 16.3 15.8 12.1 37.2 49.6 9.4 80.0 18.3 11.9 10.3 18.9 11.0 9.0 22.2 28.3 11.5 9.8 10.6 19.7 15.2 25.0 15.7 14.8 12.3 41.9 16.4 49.8 7.4 12.1 18.3 74.0 21.9 6.5 18.8 13.1 14.2 14.1 23.7 18.6 19.4 15.9 26.2 10.6 22.8 11.5 26.0 26.4 12.1 20.4 16.3 18.3 18.0 13.5 24.5 52.1 36.3 15.3 11.1 12.0 13.9 20.6 23.6 20.7 24.5 23.9 14.1 50.9 10.2 22.0 11.2 28.5 19.8 17.8 23.2 15.5 22.8 13.2 6.9 15.2 82.6 20.1 27.4 16.5 53.7 15.2 14.7 38.7 24.3 22.2 18.5 8.7 17.9 18.5 11.8 5.3 42.1 6.0 8.0 49.8 12.1 12.3 10.5 8.3 41.9 10.1 11.5 7.8 16.4 7.4 43.0 38.4 11.9 18.3 8.8 11.4 7.0 11.7 14.4 12.4 11.5 10.6 12.1 9.8 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 23.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB017782, HPA043704" Approved "CAB017782: , HPA043704: " "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favourable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.7 3.2 1.5 8.5 1.5 1.9 7.9 1.3 1.5 5.4 15.6 1.0 5.1 9.3 4.4 13.0 4.8 3.5 5.9 2.9 1.7 1.0 8.6 14.3 6.2 6.6 2.5 1.0 3.3 4.2 1.1 4.6 6.0 3.1 7.4 10.3 4.5 3.6 5.4 2.0 1.6 23.4 2.6 2.3 9.8 4.8 4.1 0.5 10.8 2.6 4.3 6.2 3.1 3.0 6.3 8.1 12.3 7.1 8.6 8.5 3.9 18.8 2.4 2.1 2.8 5.7 5.8 4.6 6.9 7.2 7.7 8.9 3.1 4.0 9.1 5.5 4.4 3.0 3.8 4.5 7.9 8.6 2.0 6.2 2.6 2.4 5.5 2.8 8.6 4.7 5.8 5.2 0.5 6.7 5.4 2.6 8.5 3.4 8.1 8.8 2.1 2.9 4.0 2.1 3.8 8.2 11.0 1.1 1.4 0.3 8.1 4.7 6.7 8.3 6.8 4.6 2.7 7.0 1.1 1.7 3.3 8.0 4.1 6.3 2.1 5.3 6.4 12.3 4.8 7.1 3.5 6.3 5.0 4.8 8.1 5.4 4.8 5.8 11.2 8.6 6.8 4.7 8.5 3.9 1.5 1.5 1.3 1.5 1.7 1.0 2.5 1.0 3.1 0.5 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391245-18401218 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "intestine: 28.4;liver: 75.5" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.8;RT4: 4.1;SCLC-21H: 5.7;SK-BR-3: 3.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043704 Uncertain "HPA043704: " "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.2 0.1 0.2 2.3 0.3 0.0 0.3 0.1 0.2 0.3 14.0 0.1 0.1 13.0 0.4 0.4 0.1 0.2 0.3 0.4 0.1 0.1 0.6 75.5 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.3 5.1 0.1 0.1 0.1 0.1 0.1 28.4 0.4 0.2 0.6 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 1.4 0.0 0.0 0.2 0.3 0.1 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 0.9 0.0 2.8 4.1 5.7 0.1 0.1 3.6 0.0 1.0 0.5 1.5 1.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.1 0.2 0.2 0.3 0.1 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640832-73642393 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 140.4" "Cell line enriched" "Detected in some" 15 "Hep G2: 16.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA067855: , HPA074519: " "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.7 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 140.4 15.8 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 1.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 16.5 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 NAT8L "FLJ37478, Hcml3" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059512-2069089 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 45.9;brain: 45.9;testis: 11.8" "Cell line enhanced" "Detected in many" "NB-4: 14.4;SCLC-21H: 18.6;SK-MEL-30: 14.8" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 28 "plasmacytoid DC: 3.8" "Lineage enriched" "Detected in single" 28 "dendritic cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria Mitochondria "HPA040677: AB_10794745" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavourable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 45.9 2.0 23.5 1.3 28.3 1.2 7.9 16.4 45.9 1.2 1.5 7.4 0.3 1.3 1.6 2.8 1.3 2.4 1.3 2.1 20.8 12.9 8.2 1.2 1.2 1.4 16.4 12.6 1.4 3.9 1.2 5.6 1.3 12.8 2.4 1.3 1.2 3.8 3.2 7.3 2.4 1.5 1.4 6.5 1.5 1.6 11.8 8.2 0.0 1.6 0.0 1.2 1.2 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 6.5 3.6 7.2 0.7 0.0 4.1 0.1 0.0 0.2 0.0 2.9 0.2 0.0 1.3 0.0 0.1 8.0 0.0 0.1 0.0 9.4 0.1 1.4 4.6 1.2 9.9 4.9 0.0 0.1 0.0 0.0 0.0 7.7 0.0 0.2 4.3 0.1 14.4 10.1 2.9 0.5 1.7 0.2 0.1 0.3 18.6 6.2 4.7 0.0 14.8 0.5 5.8 0.0 0.0 2.4 0.1 3.8 0.0 0.0 0.1 0.0 4.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 23.5 28.3 16.4 32.7 20.8 12.9 16.4 12.6 12.8 8.2 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: , HPA070520: " "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 9.8 10.0 15.3 7.3 18.0 8.9 10.5 15.9 17.1 13.7 8.9 13.5 4.9 12.5 13.0 11.5 10.8 10.0 8.3 8.8 20.8 12.2 11.9 8.8 9.4 8.2 10.8 9.9 17.2 10.3 23.9 16.0 10.1 14.2 9.6 10.1 19.9 10.6 13.0 42.5 9.3 10.9 11.6 9.7 9.6 7.6 11.4 10.7 8.5 7.0 12.2 9.3 9.7 10.8 2.5 5.5 14.2 3.5 3.4 4.1 1.8 6.6 4.9 8.7 4.5 9.6 8.8 13.3 3.5 7.1 4.5 4.0 4.6 2.8 4.8 1.5 6.4 1.6 5.2 3.0 4.9 22.8 7.5 17.2 2.0 1.9 6.0 7.9 14.4 14.0 4.6 4.3 3.5 4.5 10.4 8.0 6.8 4.4 7.0 2.8 4.1 3.3 5.5 40.1 2.4 4.9 9.0 8.0 6.3 8.2 5.0 3.6 6.0 4.0 4.9 7.5 5.9 5.1 3.5 9.3 8.0 8.4 4.3 5.0 3.7 11.0 3.5 6.9 3.8 2.7 4.1 1.8 3.4 4.1 2.6 2.5 3.3 4.0 14.2 3.4 2.8 5.5 3.7 1.8 15.3 18.0 15.9 17.1 20.8 12.2 10.8 9.9 14.2 10.7 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501902-47656877 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavourable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 20.1 8.9 6.6 34.0 7.4 11.1 15.7 11.9 9.9 12.3 10.1 8.1 9.0 6.7 15.5 8.8 16.7 12.0 8.6 11.5 6.7 4.8 9.1 9.3 17.4 25.8 7.9 4.7 13.3 10.7 13.5 13.5 54.7 7.9 9.7 9.0 10.8 13.5 10.0 32.5 15.0 17.1 11.3 9.5 30.8 11.4 9.2 7.2 17.6 13.5 10.5 33.3 15.1 17.7 13.0 6.7 6.0 7.3 2.7 4.0 3.5 5.7 18.8 5.3 7.2 12.5 14.7 37.3 5.6 8.4 9.6 5.1 9.0 6.4 20.1 3.7 9.6 14.2 4.1 6.9 7.3 10.6 2.2 2.7 5.3 12.5 7.4 2.1 15.0 6.7 19.8 9.1 10.6 6.8 6.2 4.7 5.3 62.6 3.2 3.7 1.8 7.2 6.0 3.7 8.6 5.3 13.6 1.0 1.9 14.1 17.6 6.0 8.1 5.5 11.8 5.7 5.0 6.9 2.4 12.9 11.8 20.7 6.6 2.2 3.8 3.4 5.2 4.0 3.5 7.3 3.2 13.0 3.2 3.1 6.7 10.0 3.7 4.0 6.0 2.7 7.0 5.5 4.0 3.5 6.6 7.4 11.9 9.9 6.7 4.8 7.9 4.7 7.9 7.2 NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 10 "dendritic cells: 5.5;granulocytes: 7.2;monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved 1000000 "HPA060532: " "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavourable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavourable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" 26.3 15.5 17.3 9.9 20.2 4.9 21.3 8.6 28.3 12.9 10.2 41.7 7.3 9.3 11.8 10.0 25.5 11.0 16.9 19.6 17.9 14.4 11.4 49.2 25.2 6.1 28.5 13.8 17.3 28.9 16.5 4.7 10.0 26.1 11.3 7.3 10.8 25.4 13.5 15.3 24.9 14.7 14.3 32.8 30.1 10.2 12.6 19.6 1.4 17.3 11.9 9.8 10.5 11.5 0.6 5.5 7.2 6.5 0.1 0.6 2.9 9.8 8.7 14.6 17.7 14.7 14.7 14.7 18.1 23.8 18.1 27.2 25.8 10.4 6.7 18.4 36.0 16.9 7.8 36.7 12.1 0.8 12.2 7.9 5.7 4.0 10.9 5.9 14.5 20.0 15.3 21.8 9.9 24.6 7.5 2.4 17.6 8.3 0.7 1.8 6.8 10.4 11.4 12.2 2.9 10.6 10.0 4.4 15.4 10.9 34.3 14.5 18.3 1.4 12.0 31.0 28.1 13.4 14.8 5.4 1.4 2.5 25.4 9.2 11.9 1.7 6.5 4.4 0.1 2.3 0.0 0.6 0.0 0.6 5.5 0.1 0.1 0.2 7.2 0.1 5.5 0.4 0.0 2.9 17.3 20.2 8.6 28.3 17.9 14.4 28.5 13.8 26.1 19.6 NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 50.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA051515 Approved Approved Cytosol 72000 Cytosol "HPA051515: " "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" 12.6 14.6 7.9 19.2 11.3 37.5 11.8 30.2 12.2 16.6 10.7 13.8 13.4 8.9 18.4 14.8 14.4 12.8 15.5 9.3 9.6 8.4 11.0 9.4 14.7 21.9 7.3 8.8 15.1 12.3 17.3 26.5 14.1 9.2 13.6 10.5 14.7 20.1 17.2 16.4 15.1 14.4 13.4 7.5 31.8 11.8 13.5 9.2 35.3 12.2 8.2 19.3 12.3 13.3 3.1 6.8 5.8 5.3 2.2 7.1 3.2 4.3 3.6 7.4 11.4 9.2 10.6 3.8 5.0 10.8 5.8 6.0 1.9 5.3 3.9 3.1 9.6 5.0 3.6 5.3 4.8 10.3 3.6 3.9 2.7 3.0 16.2 4.9 50.2 10.1 6.5 10.1 10.4 7.6 3.6 14.9 7.4 3.3 5.8 5.5 2.1 15.2 3.5 3.7 2.4 5.0 3.0 2.5 4.2 4.5 10.6 3.5 8.1 7.6 12.2 2.9 3.5 3.9 3.6 7.5 3.3 5.1 3.4 7.6 2.3 1.4 5.3 2.1 5.5 3.7 6.5 2.5 4.7 4.8 4.0 3.1 5.6 7.1 5.8 2.2 3.5 6.8 3.1 3.2 7.9 11.3 30.2 12.2 9.6 8.4 7.3 8.8 9.2 9.2 NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258648 "Enzymes, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 22.2;lymphoid tissue: 6.8;pituitary gland: 7.6" "Cell line enriched" "Detected in single" 19 "MOLT-4: 18.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 17.0;cerebellum: 22.2;cerebral cortex: 5.7" "Cell type enhanced" "Detected in some" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056189 Uncertain "HPA056189: " "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" 0.3 2.0 3.2 0.3 17.0 0.6 0.3 22.2 6.9 2.1 0.4 0.0 0.0 0.3 0.4 0.2 0.3 1.3 0.4 0.3 2.3 2.0 0.9 4.6 0.4 0.6 0.9 1.7 0.6 0.2 0.2 7.6 0.4 1.7 0.5 0.4 1.3 0.2 1.2 0.3 0.4 0.4 0.4 0.6 6.8 1.0 0.5 2.4 6.8 0.6 0.0 0.4 0.3 0.3 0.3 0.4 1.3 0.2 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.9 1.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 1.3 0.4 0.1 0.4 0.0 0.0 3.2 17.0 22.2 5.7 2.3 2.0 0.9 1.7 1.7 2.4 NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 34.6" "Cell line enriched" "Detected in some" 4 "RH-30: 17.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 17 "pons and medulla: 34.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain "HPA011129: AB_1079460" "unprognostic (5.58e-2)" "unprognostic (5.90e-2)" "unprognostic (4.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (6.55e-2)" 0.1 0.0 1.3 0.0 1.7 0.0 0.1 0.2 3.4 1.4 0.3 0.3 0.3 0.1 1.5 0.0 0.1 0.1 0.3 0.1 0.7 1.9 0.1 0.0 0.1 0.0 1.3 1.4 5.7 0.1 0.0 0.6 0.0 34.6 1.5 0.1 0.0 0.5 0.6 0.1 0.2 0.1 1.6 1.0 2.5 1.1 0.7 0.0 0.0 0.1 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.7 0.2 1.7 0.7 1.9 1.3 1.4 34.6 0.0 NDUFAF7 "C2orf56, MidA, PRO1853" ENSG00000003509 "NADH:ubiquinone oxidoreductase complex assembly factor 7" Q7L592 2 37231631-37253403 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045217 Uncertain "HPA045217: AB_10960395" "unprognostic (6.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.13e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (1.48e-4)" "prognostic favourable (3.08e-4)" "unprognostic (5.44e-2)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (8.12e-3)" "unprognostic (5.94e-2)" "unprognostic (3.48e-2)" "unprognostic (1.03e-1)" "unprognostic (5.73e-2)" "unprognostic (8.67e-3)" 7.1 14.3 10.1 7.5 15.9 7.3 8.3 24.1 17.0 9.3 12.6 7.7 6.1 6.4 10.0 11.0 6.7 6.4 8.1 18.3 9.4 9.7 12.2 13.5 6.6 8.3 9.4 10.5 8.8 7.6 9.4 15.2 7.9 14.5 7.7 8.1 7.8 7.0 7.9 21.0 5.8 7.3 9.8 7.2 7.8 7.1 44.4 10.5 8.2 6.4 6.5 7.5 7.8 7.2 8.9 9.9 5.3 8.1 6.9 8.3 4.1 16.0 8.6 10.8 9.7 7.0 15.0 6.1 5.2 8.6 9.3 11.8 18.3 6.9 13.6 6.7 5.0 12.1 13.4 6.8 11.0 9.3 9.8 10.0 10.7 16.6 8.7 9.8 5.2 11.6 11.4 7.7 4.7 14.3 12.2 9.3 5.4 6.0 9.9 10.8 14.3 7.4 9.0 8.5 11.5 12.9 6.0 11.5 9.2 6.8 11.6 11.4 7.0 4.0 2.8 7.8 10.4 9.5 9.7 8.1 4.6 15.4 11.4 13.6 6.6 4.6 8.1 4.5 8.3 7.0 3.8 8.9 7.4 7.1 9.9 7.8 7.4 6.4 5.3 6.9 4.9 8.1 8.3 4.1 10.1 15.9 24.1 17.0 9.4 9.7 9.4 10.5 14.5 10.5 NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase" P46934 15 55826922-55993746 "Enzymes, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" 14.1 4.1 2.5 3.1 3.3 4.5 8.7 1.5 2.7 9.9 9.4 2.8 3.4 3.4 10.1 4.1 8.2 3.8 4.5 4.1 2.9 2.4 8.6 21.5 7.2 2.1 3.5 1.3 6.6 2.8 6.5 6.7 20.1 3.5 8.4 3.4 5.4 4.0 6.4 57.7 7.1 15.2 10.9 6.0 5.9 4.4 2.6 3.1 9.4 5.7 9.0 3.3 11.9 8.9 0.1 1.6 1.2 2.8 1.2 2.9 0.9 7.3 11.4 3.1 3.0 4.1 6.8 5.1 14.1 22.3 10.4 10.5 5.1 2.2 1.8 3.7 5.3 12.2 3.4 9.3 17.1 4.1 2.1 9.1 2.7 2.6 21.9 4.0 0.9 11.5 23.0 12.5 21.1 8.5 3.9 0.0 30.5 3.8 5.3 0.0 0.8 1.7 3.9 24.7 1.0 4.3 14.6 0.3 2.0 6.3 4.5 5.6 5.6 3.0 29.6 23.2 7.7 4.9 22.9 1.2 2.6 4.8 15.7 8.5 5.5 0.6 1.0 0.0 1.3 2.8 2.9 0.1 1.5 1.2 0.8 0.0 1.4 1.6 1.2 1.2 1.9 1.6 1.3 0.9 2.5 3.3 1.5 2.7 2.9 2.4 3.5 1.3 3.5 3.1 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" Q96PU5 18 58044367-58401540 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 50.1;SK-MEL-30: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favourable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 5.9 6.8 9.1 5.4 38.8 13.2 15.8 21.4 24.7 5.0 22.6 3.2 18.2 11.1 3.6 6.1 7.0 6.0 7.6 12.7 9.8 7.1 29.9 10.1 26.9 2.5 7.2 14.9 3.0 33.2 9.2 16.5 13.0 4.1 30.6 25.2 12.2 16.5 23.2 38.3 5.9 26.8 8.2 3.2 3.1 26.0 4.6 8.8 0.8 9.1 5.5 5.1 14.9 9.3 1.4 0.4 4.7 0.7 0.9 8.1 0.5 18.4 6.6 3.9 5.8 1.4 0.5 13.6 5.2 23.7 13.4 20.5 7.7 10.0 3.9 16.1 2.0 13.4 5.2 23.1 27.7 9.2 4.6 2.8 4.1 50.1 0.7 0.1 1.7 3.5 15.1 18.1 22.0 1.0 4.8 1.7 5.5 4.5 0.2 0.2 3.4 10.2 3.8 5.3 4.5 13.3 24.1 4.9 1.3 4.3 1.3 39.1 7.9 1.6 7.9 36.2 10.9 2.0 22.3 2.3 3.9 2.4 7.4 2.8 2.9 4.7 0.6 1.7 0.4 0.7 1.0 1.4 1.3 0.3 0.3 0.6 0.8 0.6 0.3 0.9 0.1 0.4 8.1 0.5 9.1 38.8 21.4 24.7 9.8 7.1 7.2 14.9 4.1 8.8 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392857-169612629 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favourable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 9.6 10.5 13.5 9.2 15.8 6.0 8.7 20.7 14.5 13.6 8.4 12.5 7.1 5.4 12.4 9.1 7.9 15.7 10.2 11.4 13.7 13.2 10.2 6.9 7.7 8.0 15.9 11.3 16.3 6.6 15.3 16.5 7.2 16.0 11.6 7.7 8.9 6.4 10.6 7.1 4.7 5.7 11.1 18.2 8.0 8.1 18.3 14.8 14.7 13.3 6.4 7.4 10.0 8.2 4.5 3.3 6.7 3.3 2.2 5.3 1.3 4.2 1.9 7.8 8.4 12.1 13.6 2.5 9.0 8.1 7.2 6.9 2.4 5.1 11.3 1.7 7.8 1.4 7.3 7.6 8.2 12.4 5.0 7.6 7.8 2.9 7.2 7.7 6.1 10.8 4.4 7.3 12.9 7.0 13.5 21.6 9.2 2.7 9.9 3.4 2.5 4.5 6.1 5.1 3.6 7.6 5.0 8.5 9.7 6.5 3.2 6.0 4.0 3.4 8.4 4.6 4.2 4.8 6.0 8.7 13.4 8.7 7.6 3.8 8.0 6.7 2.1 1.8 4.4 3.3 4.8 4.4 3.4 2.7 1.5 4.5 5.1 5.3 1.1 2.2 1.6 3.3 3.2 1.3 13.5 15.8 20.7 12.9 13.7 13.2 15.9 11.3 16.0 14.8 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 31.4" "Cell line enhanced" "Detected in many" "BJ: 7.6;LHCN-M2: 10.5;U-2 OS: 8.9" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favourable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.4 0.5 4.5 0.5 14.6 0.4 14.2 0.6 6.8 1.6 2.0 1.1 2.0 2.5 0.9 8.3 2.0 10.5 2.1 3.1 8.4 3.8 1.4 2.5 4.5 0.6 0.8 6.7 2.7 0.8 0.5 9.0 0.3 3.4 1.9 0.7 1.3 0.5 1.4 10.5 0.4 1.0 1.2 0.8 0.6 1.1 31.4 1.3 0.3 0.8 0.3 0.7 1.4 0.4 0.4 0.2 1.9 0.1 0.1 0.6 0.1 1.0 2.0 1.0 1.2 0.9 2.0 0.4 7.6 1.2 2.1 1.9 0.0 0.5 0.7 1.9 3.2 0.1 0.5 0.5 2.3 1.4 0.8 0.2 4.1 3.7 0.2 0.4 1.0 2.4 0.5 3.2 0.1 1.4 0.1 0.7 10.5 0.1 0.8 0.5 0.7 0.3 1.0 0.4 0.3 4.0 0.6 0.2 0.2 1.2 0.4 0.6 6.1 0.4 0.9 5.6 8.9 0.3 0.7 0.3 0.2 0.5 4.8 0.8 2.1 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.5 0.4 0.0 0.4 0.1 0.5 1.9 0.1 0.0 0.2 0.0 0.1 4.5 14.6 0.6 6.8 8.4 3.8 0.8 6.7 3.4 1.3 NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm Nucleoplasm "HPA016908: AB_1854364" "unprognostic (9.15e-3)" "prognostic favourable (7.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (4.85e-3)" "unprognostic (2.48e-5)" "unprognostic (5.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "prognostic favourable (5.92e-6)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" 3.9 5.8 9.3 2.7 11.1 0.5 8.7 2.7 7.6 7.3 2.8 11.2 8.4 2.0 6.5 16.0 3.2 26.9 6.0 2.9 9.1 10.0 8.2 1.1 5.5 1.7 7.8 5.4 8.7 2.8 5.0 9.3 4.6 17.3 4.0 3.3 3.0 3.8 6.7 1.7 2.8 2.6 4.3 7.3 1.8 2.3 17.8 5.5 0.2 12.3 2.5 1.7 4.2 3.0 0.9 1.0 1.1 1.3 0.3 2.9 0.3 5.8 2.4 1.7 5.1 6.9 10.4 1.0 2.9 5.4 4.4 3.4 2.2 8.2 0.3 2.1 5.1 3.2 0.5 5.0 6.2 0.5 0.7 0.8 0.4 1.0 2.3 0.6 1.5 4.3 8.4 4.7 2.1 0.9 0.2 0.9 7.4 4.1 0.1 0.5 0.5 2.3 0.0 0.2 0.1 10.1 2.3 2.2 2.4 1.4 0.1 1.9 4.8 0.1 0.9 4.6 2.2 3.6 1.3 1.3 2.3 0.1 3.2 0.2 0.8 0.0 0.3 1.1 0.6 1.3 1.2 0.9 2.9 2.6 0.5 0.6 1.0 0.8 0.9 0.3 0.9 1.0 1.5 0.3 9.3 11.1 2.7 7.6 9.1 10.0 7.8 5.4 17.3 5.5 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0;testis: 41.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.2" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: " "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavourable (9.47e-6)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 1.1 0.7 0.6 6.7 0.5 7.4 1.3 0.3 0.9 0.9 2.5 0.3 0.3 3.4 0.3 1.2 4.2 0.7 1.4 0.9 1.0 0.3 0.6 0.6 1.0 3.9 0.3 0.3 0.6 0.3 0.0 0.3 1.2 0.4 0.9 3.6 0.4 1.0 0.3 0.3 1.8 3.0 0.6 0.6 1.6 1.1 41.0 0.4 14.0 0.3 1.5 4.8 0.6 1.6 1.8 0.9 2.7 0.5 3.9 4.3 0.9 30.3 21.9 16.8 12.0 1.0 1.7 18.5 11.7 11.0 20.7 17.8 11.7 29.8 16.1 5.7 9.0 16.3 14.5 8.8 26.1 24.6 12.1 7.7 19.1 15.7 0.1 15.2 10.5 0.5 1.0 15.9 17.2 13.2 21.1 28.4 20.7 8.4 16.5 10.3 15.9 11.2 16.4 25.7 24.5 7.2 8.7 15.2 16.9 16.9 19.0 14.7 29.2 9.1 6.9 10.3 20.5 20.3 31.4 11.8 21.7 21.3 9.0 11.7 17.1 2.7 0.5 0.4 0.5 0.3 0.2 1.5 0.6 0.3 0.1 1.8 1.1 0.7 2.4 3.9 0.4 0.9 4.3 0.9 0.6 0.5 0.3 0.9 1.0 0.3 0.3 0.3 0.4 0.4 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules Microtubules "HPA019062: , HPA043230: " "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 7.7 2.8 7.1 5.4 12.9 7.1 7.3 3.2 7.1 7.0 13.8 20.4 3.1 7.8 9.1 5.8 3.9 6.0 6.4 5.0 8.7 5.2 6.1 5.7 7.2 4.2 14.0 9.5 7.9 6.4 2.2 3.7 14.8 11.3 5.4 15.0 6.8 5.2 5.0 4.1 5.4 11.7 7.3 9.6 3.9 4.6 14.7 13.3 2.4 5.0 2.7 4.3 6.5 6.0 4.4 7.8 5.9 7.7 2.0 3.5 1.6 0.2 1.4 13.1 7.5 4.2 6.6 0.2 4.2 4.3 5.1 5.7 5.0 7.3 0.0 0.2 5.2 0.9 0.2 3.2 3.1 8.7 6.9 1.0 1.4 13.6 5.4 12.6 6.8 4.8 5.8 2.6 12.2 7.7 1.8 4.4 5.2 3.6 0.6 15.2 12.9 0.3 0.3 1.1 4.7 7.3 1.3 1.3 9.1 1.9 4.0 8.8 1.7 16.2 6.6 0.7 4.3 4.0 4.5 4.7 1.6 8.8 1.1 5.0 7.1 5.9 7.7 5.3 2.1 6.6 1.3 4.4 2.5 1.3 7.8 2.5 1.7 0.6 0.5 2.0 1.5 6.9 3.5 1.6 7.1 12.9 3.2 7.1 8.7 5.2 14.0 9.5 11.3 13.3 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708449-52770949 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol Cytosol "HPA015750: AB_1854367, HPA058543: " "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favourable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 7.2 10.7 15.5 9.1 15.7 7.3 11.0 20.2 16.1 10.6 8.4 10.6 9.6 7.6 10.3 10.7 8.1 15.8 7.5 7.4 12.5 14.2 11.6 12.4 7.7 8.8 12.7 8.6 15.8 10.2 13.4 17.6 8.7 11.9 9.4 9.7 9.1 8.5 11.3 10.8 5.3 6.6 9.5 10.7 7.9 11.0 47.7 12.4 11.1 15.5 5.0 10.4 9.3 10.7 5.1 6.4 12.4 11.8 4.6 5.2 5.5 12.8 10.0 13.7 10.8 12.6 9.1 14.9 9.1 12.3 17.1 17.3 8.7 9.6 13.2 4.3 8.9 6.0 16.7 10.7 23.0 13.1 7.0 10.3 12.2 11.1 7.8 25.1 10.4 5.6 9.9 21.9 14.6 6.4 12.8 10.7 10.7 10.9 13.5 9.2 11.9 9.9 11.9 12.0 9.7 9.6 18.5 10.1 6.1 19.1 11.8 9.0 11.0 15.2 5.8 11.5 11.7 18.3 16.8 12.0 17.5 13.0 13.1 11.9 12.4 12.4 11.8 5.8 4.6 7.3 5.2 3.6 4.0 4.8 6.4 5.1 4.9 4.2 1.8 4.6 4.8 3.2 3.1 5.5 15.5 15.7 20.2 16.1 12.5 14.2 12.7 8.6 11.9 12.4 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129078 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.8;fallopian tube: 12.7;testis: 15.7" "Cell line enhanced" "Detected in some" "T-47d: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035565, HPA041399" Enhanced "HPA035565: AB_10672095, HPA041399: " "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.6 0.3 3.2 1.4 3.2 0.7 0.9 0.4 2.6 0.9 0.4 5.4 0.3 0.5 2.5 3.0 0.4 12.7 0.5 1.3 3.2 1.6 0.9 0.3 4.9 0.5 0.7 1.3 2.8 0.5 0.9 5.3 0.8 11.8 1.5 0.4 0.3 0.5 0.3 0.6 0.5 0.4 0.5 0.9 0.4 0.3 15.7 2.1 0.0 0.7 0.0 0.3 0.4 0.4 0.9 1.1 2.5 0.5 0.6 0.4 0.0 0.5 0.6 0.4 2.2 0.3 1.4 2.8 0.0 0.0 0.0 0.3 0.2 1.4 0.7 0.2 0.0 0.5 0.3 0.5 0.1 0.2 0.4 0.8 0.8 0.5 0.4 1.4 1.7 0.4 1.1 0.2 0.8 0.3 1.5 1.0 0.0 1.7 0.7 1.1 0.6 0.8 0.3 0.2 0.0 2.4 0.6 0.8 1.1 0.5 0.0 1.2 4.2 1.7 0.6 0.2 0.3 0.2 0.3 0.4 0.2 0.4 0.1 0.3 0.4 2.5 0.5 0.1 0.3 0.3 0.4 0.5 0.2 0.2 0.1 0.9 0.3 0.3 0.9 0.6 0.1 1.1 0.2 0.0 3.2 3.2 0.4 2.6 3.2 1.6 0.7 1.3 11.8 2.1 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB045993: AB_2150651, HPA056828: " "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavourable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 14.8 5.3 26.1 22.2 29.1 12.8 18.8 7.2 21.2 20.5 15.6 13.4 4.3 12.5 9.2 7.5 6.8 8.5 18.4 7.0 17.1 16.6 12.9 51.9 17.0 18.1 19.4 13.3 11.2 20.5 1.6 6.4 21.4 14.7 14.8 16.6 18.5 16.9 13.2 5.5 5.1 18.2 23.4 13.0 11.3 19.0 5.8 12.9 4.0 6.3 1.9 22.0 17.7 10.1 21.9 11.5 29.0 18.8 8.3 3.8 7.6 7.7 12.7 12.3 4.8 23.4 30.4 15.3 9.7 15.6 15.1 12.6 12.1 14.5 9.4 15.6 18.8 1.5 6.3 28.3 10.3 10.3 5.6 25.9 10.7 21.1 27.9 4.6 65.0 40.6 4.6 14.3 14.9 16.4 4.6 0.4 27.0 8.1 0.2 5.1 3.1 11.6 10.0 9.2 4.8 16.2 2.8 5.5 1.9 3.2 6.1 13.8 13.1 19.1 32.1 11.1 11.2 7.6 6.6 2.1 2.6 5.4 13.9 10.6 14.7 10.2 18.8 29.0 3.8 12.3 2.4 21.9 2.3 3.2 11.5 9.0 0.4 1.6 23.4 8.3 14.7 10.6 2.8 7.6 26.1 29.1 7.2 21.2 17.1 16.6 19.4 13.3 14.7 12.9 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156963-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 83.7;fHDF/TERT166: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 31.7 31.4 24.9 15.2 23.0 5.6 23.7 7.8 15.6 19.3 20.6 25.5 13.7 11.3 24.5 11.4 18.7 12.8 15.1 74.7 23.9 20.4 16.1 16.0 22.3 14.9 26.8 13.4 17.2 11.1 14.6 17.6 40.5 18.0 20.0 13.2 11.8 13.5 21.3 29.9 10.6 15.8 30.9 34.9 16.4 11.7 9.5 22.6 18.0 14.9 12.8 12.5 27.4 20.7 1.6 2.1 6.1 2.2 3.8 14.7 1.4 7.0 1.8 2.2 0.9 5.9 6.8 2.6 83.7 35.0 34.1 16.2 3.4 7.0 2.5 6.0 113.0 4.3 3.4 4.5 34.5 7.9 4.9 3.4 8.0 1.4 7.1 5.8 7.1 4.2 3.9 22.4 6.7 6.4 2.7 6.3 15.6 2.2 5.0 3.4 1.2 1.4 2.6 5.6 4.4 5.8 3.6 1.4 2.6 13.9 8.0 9.3 5.9 5.3 14.2 9.6 8.1 27.4 8.7 4.4 4.0 1.7 4.2 5.3 7.4 1.9 2.2 3.0 3.2 1.9 14.7 1.3 3.6 4.6 2.1 1.6 2.9 3.6 6.1 3.8 1.7 1.4 6.0 1.4 24.9 23.0 7.8 15.6 23.9 20.4 26.8 13.4 18.0 22.6 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 14.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavourable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favourable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 3.5 4.6 2.9 11.9 4.5 2.0 4.3 1.7 4.9 5.3 4.0 4.7 1.4 4.2 2.1 5.0 4.8 5.9 4.4 1.6 2.9 1.9 10.4 6.9 5.7 7.8 2.3 2.1 4.4 6.4 8.5 9.7 8.7 5.6 5.6 3.2 5.2 5.3 4.1 0.9 4.4 6.5 1.7 3.0 8.4 4.9 4.9 1.4 4.8 10.7 3.5 15.6 4.5 3.0 4.7 14.7 3.2 1.0 1.3 1.1 0.8 2.1 3.5 3.7 2.9 2.0 2.2 11.4 1.0 2.2 1.4 1.8 5.4 5.1 13.2 3.7 2.8 3.9 5.4 4.9 1.4 3.5 6.6 2.9 5.6 10.0 3.5 1.8 3.9 5.1 1.9 2.6 6.1 0.9 4.3 1.3 1.5 4.7 1.8 3.4 3.4 1.1 4.9 2.4 5.8 7.3 5.8 6.7 1.6 3.1 6.5 1.6 9.7 2.4 0.9 1.3 2.4 1.7 1.0 1.5 1.7 8.9 2.1 1.6 3.2 3.2 0.9 1.2 0.8 0.4 0.9 3.0 0.7 0.7 0.1 4.7 0.8 1.1 0.5 1.3 1.0 14.7 0.5 0.8 2.9 4.5 1.7 4.9 2.9 1.9 2.3 2.1 5.6 1.4 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved Approved Mitochondria 190000 Mitochondria "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favourable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 17.0 20.4 12.7 17.7 17.4 7.3 15.1 15.4 13.3 18.6 18.7 18.3 23.5 14.0 25.0 13.8 15.6 20.0 15.9 23.5 11.4 8.7 14.0 13.3 12.9 16.2 20.2 10.6 25.6 15.7 24.7 23.6 14.3 13.0 15.3 8.1 15.4 12.4 18.9 36.2 10.6 15.3 24.7 14.5 14.7 14.8 16.6 18.2 21.5 17.0 14.1 14.4 23.6 18.7 6.0 6.4 7.5 5.4 5.5 6.2 3.1 10.1 12.0 15.2 16.9 19.5 26.8 17.3 16.5 11.6 8.1 7.9 10.1 8.9 17.4 0.1 11.3 14.0 11.6 6.4 9.0 14.2 6.7 8.5 12.0 7.3 12.8 5.1 11.4 18.3 7.6 8.4 6.4 10.1 9.6 11.3 9.7 1.1 10.8 5.2 9.0 6.1 17.5 19.4 9.0 6.1 12.4 7.3 18.7 13.3 6.4 12.7 15.8 14.8 15.2 12.3 5.2 14.3 6.4 18.3 19.5 17.6 9.0 8.7 8.3 7.5 5.4 5.8 4.2 5.0 5.9 2.8 4.8 3.9 6.4 6.0 6.2 5.9 5.5 5.5 3.5 1.8 2.6 3.1 12.7 17.4 15.4 13.3 11.4 8.7 20.2 10.6 13.0 18.2 NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493979-103592552 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 37.1;skeletal muscle: 83.5" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HeLa: 7.6;HMC-1: 6.5;SCLC-21H: 16.2;SiHa: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "intermediate monocyte: 16.0;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 17 "monocytes: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced "HPA044204: AB_10959383" "unprognostic (1.21e-2)" "unprognostic (8.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-4)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (4.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (8.61e-3)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.91e-4)" "unprognostic (3.23e-1)" 1.1 3.9 18.5 3.0 17.5 2.0 1.0 28.2 27.2 6.1 8.6 0.6 1.2 7.7 13.2 11.0 3.6 2.1 2.0 1.1 12.0 7.6 1.3 1.1 1.3 1.3 4.5 18.9 2.1 12.8 2.9 6.5 13.3 6.1 2.8 7.3 7.8 1.5 1.7 83.5 1.9 11.7 11.7 1.2 2.0 4.4 7.5 2.1 0.0 1.2 8.5 1.1 9.2 1.7 0.4 2.1 1.0 37.1 0.2 0.4 1.2 0.8 0.2 1.3 0.0 0.4 0.1 12.9 0.5 0.8 0.2 0.1 0.3 0.3 0.4 0.7 0.1 0.7 0.4 0.2 0.1 0.3 0.7 0.2 7.6 0.6 0.0 0.3 6.5 0.2 0.5 0.1 0.6 0.0 2.1 0.4 0.2 1.1 1.3 0.8 0.0 3.9 0.2 0.6 1.4 0.0 0.5 16.2 5.5 8.1 0.0 0.4 0.7 1.5 0.0 0.1 0.9 0.2 0.2 0.9 0.2 0.3 0.5 0.0 0.3 0.2 1.0 0.2 0.3 16.0 0.4 0.4 0.4 0.4 2.1 0.3 0.4 0.3 1.0 0.2 37.1 1.7 0.1 1.2 18.5 17.5 28.2 27.2 12.0 7.6 4.5 18.9 6.1 2.1 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641266-172691540 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.0;T-47d: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported Vesicles Vesicles "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavourable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 26.6 11.8 7.5 10.3 3.2 1.5 23.9 0.6 7.0 21.4 17.5 5.6 31.2 5.7 26.7 24.7 14.0 15.8 23.0 19.2 10.7 4.2 7.6 4.4 10.5 7.8 3.1 3.2 20.9 4.8 4.1 6.0 5.1 2.7 20.7 11.6 6.1 4.9 28.4 12.3 14.7 12.1 29.1 1.5 0.6 5.9 6.6 2.8 3.6 7.2 13.9 5.4 16.0 30.8 0.0 0.6 0.0 0.2 0.0 0.2 0.0 4.4 2.3 1.2 5.6 0.4 0.2 0.1 5.0 2.2 2.7 3.9 8.5 2.0 0.0 1.4 3.2 1.3 0.5 2.2 1.8 8.1 0.3 6.1 8.1 0.0 0.4 0.0 1.9 0.0 9.7 0.6 2.7 0.4 0.0 1.9 5.7 4.9 1.4 0.1 0.8 0.2 27.0 6.0 0.8 0.1 1.0 1.0 5.8 4.8 7.6 0.2 12.7 0.9 0.8 2.0 11.9 1.4 3.1 0.8 0.2 0.0 5.8 0.1 1.7 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.5 3.2 0.6 7.0 10.7 4.2 3.1 3.2 2.7 2.8 NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497643-96508109 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 26.3;salivary gland: 22.4;seminal vesicle: 10.8" "Cell line enhanced" "Detected in some" "BEWO: 4.1;CAPAN-2: 16.6;RPMI-8226: 10.5;RT4: 5.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "unprognostic (4.97e-2)" "unprognostic (6.07e-2)" "unprognostic (7.22e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-2)" "unprognostic (4.35e-2)" "prognostic unfavourable (6.46e-4)" "unprognostic (2.29e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (8.14e-3)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (6.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.1 0.0 0.9 0.9 0.0 0.1 0.0 0.0 1.3 0.0 0.0 5.3 0.6 1.8 0.0 0.0 0.1 0.0 26.3 0.0 0.0 0.0 0.2 1.4 0.1 0.0 22.4 10.8 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.2 0.0 6.4 0.0 0.5 0.1 0.4 0.0 0.3 0.2 0.7 0.1 0.1 0.1 3.0 1.0 0.5 0.0 0.3 0.0 0.0 4.1 0.0 0.4 0.3 0.2 2.4 16.6 0.0 1.3 0.0 2.5 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.5 2.2 5.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.3 0.1 0.0 0.7 0.1 0.0 0.0 0.1 3.0 NFS1 "IscS, NifS" ENSG00000244005 "NFS1, cysteine desulfurase" Q9Y697 20 35668055-35699359 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB034314, HPA051801, HPA054755" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB034314: AB_2235980, HPA051801: AB_2681616, HPA054755: AB_2682594" "unprognostic (1.72e-1)" "unprognostic (2.96e-1)" "unprognostic (1.27e-2)" "unprognostic (5.88e-3)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (9.00e-2)" "unprognostic (1.73e-1)" "unprognostic (6.52e-3)" "unprognostic (3.93e-2)" "prognostic favourable (4.72e-6)" "unprognostic (2.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.64e-2)" "unprognostic (5.54e-2)" 10.2 28.0 16.9 6.7 19.3 3.7 9.7 15.3 20.8 11.2 11.7 12.0 10.0 11.0 8.4 9.9 10.1 11.7 9.9 19.2 14.6 14.0 36.9 33.0 7.8 7.0 16.5 15.5 12.5 14.0 20.7 14.8 7.8 14.3 9.5 13.0 12.2 12.6 12.2 19.7 9.5 9.6 10.1 12.4 6.6 10.3 25.3 15.8 4.9 10.2 8.4 10.4 8.1 7.7 10.4 11.2 7.4 8.1 12.8 11.4 6.1 13.3 16.7 5.8 6.1 15.9 14.6 11.8 10.2 10.8 15.5 10.1 30.0 7.6 11.4 20.1 9.5 16.9 19.9 20.6 14.0 5.1 9.3 24.4 17.8 23.3 13.3 10.2 4.7 11.7 19.8 12.1 13.4 11.5 17.4 7.7 10.8 20.5 11.5 10.8 6.7 25.1 4.6 18.9 19.2 15.7 9.1 7.3 6.7 25.5 24.7 16.6 22.1 9.2 8.4 17.5 8.3 10.2 10.0 11.1 15.2 10.4 14.8 11.1 8.6 2.5 8.1 7.4 7.6 7.7 9.7 10.4 8.8 11.2 11.2 7.6 10.3 9.3 3.4 12.8 6.0 5.6 11.4 6.1 16.9 19.3 15.3 20.8 14.6 14.0 16.5 15.5 14.3 15.8 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122687 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 9.0;K-562: 7.6;SCLC-21H: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavourable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favourable (5.30e-4)" 2.5 3.6 5.0 1.8 6.5 2.1 4.6 2.6 8.5 1.9 3.3 7.1 1.7 3.2 2.0 6.1 2.4 3.5 2.7 3.9 5.0 5.1 1.9 9.0 5.1 4.7 5.4 3.9 3.5 12.2 2.4 2.8 1.0 5.2 3.4 3.0 3.3 5.1 2.8 5.2 8.5 4.3 1.8 5.4 2.4 3.0 2.1 3.8 2.4 3.6 0.9 1.8 2.5 1.8 3.3 7.2 0.6 7.2 2.2 2.5 2.6 3.3 2.0 0.8 0.1 1.8 1.7 0.0 3.4 1.1 1.3 0.7 0.1 2.8 0.1 9.0 2.5 4.0 0.0 2.2 1.0 0.1 1.1 0.5 1.0 0.2 2.8 0.0 2.2 2.9 3.3 1.3 1.2 2.8 7.6 0.1 2.8 3.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 1.8 3.6 8.0 0.1 6.8 5.7 2.0 4.1 2.2 0.5 0.2 1.7 2.4 0.0 0.1 0.0 0.1 0.1 0.0 3.4 0.5 6.6 0.6 1.1 7.2 1.2 3.3 1.7 0.8 7.2 2.3 2.5 1.6 0.5 2.2 3.2 0.9 1.8 2.6 5.0 6.5 2.6 8.5 5.0 5.1 5.4 3.9 5.2 3.8 NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.7;pituitary gland: 9.7" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HDLM-2: 4.8;PC-3: 5.5;U-87 MG: 6.0" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Group enriched" "Detected in many" 10 "dendritic cells: 1.2;T-cells: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Uncertain Approved Cytosol Cytosol "HPA007695: " "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" 1.4 3.5 9.4 1.6 10.9 0.9 1.3 4.9 23.7 1.6 1.4 6.3 0.0 1.1 1.2 1.6 1.6 1.4 1.5 1.8 8.7 7.7 1.4 1.2 3.6 1.2 5.6 5.8 1.2 1.5 1.2 9.7 1.8 6.4 1.4 1.7 1.7 2.3 2.4 2.0 1.8 1.2 1.3 4.9 1.0 3.0 1.4 8.1 0.0 2.7 0.0 1.0 1.1 0.8 0.1 1.2 0.0 0.0 0.2 3.2 0.0 0.2 0.6 0.1 0.1 0.9 0.5 0.0 1.0 3.1 1.1 4.4 0.1 0.0 0.4 0.6 0.8 0.3 0.6 0.0 2.7 4.8 0.3 0.1 0.6 0.2 1.6 0.2 0.6 1.9 0.1 0.5 0.0 0.0 0.2 0.3 0.9 0.2 0.3 0.2 0.0 5.5 0.2 0.3 0.5 0.1 0.7 0.9 0.1 1.7 0.5 0.3 0.4 1.5 0.0 0.9 0.8 0.7 0.7 1.6 0.4 0.3 6.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 3.2 0.0 9.4 10.9 4.9 11.6 8.7 7.7 5.6 5.8 6.4 8.1 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "basophil: 17.6" "Lineage enriched" "Detected in single" 32 "granulocytes: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions" Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: " "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 6.4 30.5 19.4 10.9 14.1 7.4 7.5 7.5 38.2 6.2 6.7 8.3 14.4 8.3 5.7 8.8 4.5 5.1 8.2 8.5 18.2 12.0 13.0 8.2 7.1 11.7 15.2 23.6 4.6 11.5 20.8 9.4 9.1 7.0 6.7 7.1 12.7 5.8 17.4 4.9 4.5 8.3 4.6 15.3 10.1 7.0 17.4 7.5 10.9 13.2 3.7 11.0 7.2 4.4 0.5 0.3 17.6 0.3 0.1 0.5 0.2 4.6 5.4 13.0 4.5 2.8 3.6 5.7 4.6 4.7 7.8 6.0 27.0 4.2 6.3 7.1 3.8 4.4 9.1 8.5 9.0 14.5 5.8 24.7 5.0 4.6 4.7 5.2 25.5 4.7 5.2 5.1 6.1 9.1 9.5 7.6 7.1 5.4 13.3 6.0 5.0 2.7 11.2 8.4 4.6 14.1 5.7 9.5 3.5 7.1 6.8 29.0 10.6 8.3 9.3 5.6 7.5 4.6 9.3 9.0 8.6 6.1 5.4 5.6 6.1 17.6 0.2 0.2 0.3 0.3 0.1 0.5 0.4 0.4 0.2 0.3 0.2 0.5 0.1 0.1 0.3 0.3 0.4 0.2 19.4 14.1 7.5 38.2 18.2 12.0 15.2 23.6 7.0 7.5 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153536-51162428 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 28000000 Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: " "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavourable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 25.0 29.5 38.0 28.1 30.1 27.9 29.0 19.6 41.9 16.4 25.4 13.1 10.1 15.1 17.3 22.5 30.1 22.2 13.4 14.1 41.7 39.4 19.6 56.0 14.2 28.5 34.2 34.2 15.6 43.6 13.7 17.3 16.9 38.9 14.5 36.8 14.9 34.3 14.7 14.8 22.4 12.4 29.6 20.5 22.4 13.4 11.6 11.3 19.0 18.8 32.7 41.4 22.8 15.2 24.9 36.2 0.6 19.5 17.2 20.3 18.4 47.6 95.2 32.9 45.9 13.8 22.1 55.3 37.2 25.8 77.1 58.5 74.9 28.9 83.9 38.8 34.4 25.6 62.8 63.2 66.0 40.7 84.6 55.0 73.9 103.9 28.0 60.2 25.2 21.0 39.8 58.0 54.3 46.4 81.1 27.9 45.6 80.7 71.5 69.3 39.4 86.8 43.9 64.9 77.2 59.2 33.3 45.7 52.6 19.5 53.4 34.6 55.6 40.8 29.2 49.8 45.2 30.9 76.3 36.0 83.0 98.8 30.1 51.1 37.8 0.2 15.2 0.6 13.4 19.5 20.3 24.9 14.4 14.6 36.2 17.3 16.4 17.8 0.4 17.2 11.5 20.7 12.1 18.4 38.0 30.1 19.6 41.9 41.7 39.4 34.2 34.2 38.9 11.3 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171747 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB036213: , CAB036214: , CAB036215: , HPA041113: " "unprognostic (7.21e-3)" "prognostic unfavourable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavourable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 62.1 54.6 42.3 58.2 44.1 44.2 188.9 20.1 43.7 58.9 74.0 16.3 67.7 52.5 65.0 52.0 104.3 56.8 65.3 115.1 38.2 32.1 77.3 115.7 59.0 174.7 45.0 23.7 90.7 234.3 17.5 30.4 37.9 34.0 64.0 62.7 29.9 109.4 65.8 105.3 63.3 45.1 88.3 34.6 69.4 50.2 32.3 24.4 42.5 66.9 102.0 56.6 81.3 140.8 49.3 71.3 8.3 43.7 32.6 34.5 38.2 91.8 135.0 32.3 56.4 72.3 105.5 89.2 63.7 66.3 97.5 74.3 108.9 48.9 77.3 103.2 65.2 58.8 67.8 86.9 80.3 93.1 200.5 65.0 94.2 157.6 79.0 102.5 45.5 95.5 101.5 62.9 110.7 58.0 88.9 52.1 70.2 163.4 51.3 128.2 48.2 207.4 49.2 107.1 123.4 105.6 116.1 73.7 45.7 39.2 98.5 95.6 67.9 78.7 58.8 94.0 68.0 66.8 101.2 91.1 118.3 88.5 50.8 52.2 47.1 8.3 35.1 2.0 24.7 43.7 34.5 49.3 33.0 26.9 61.5 36.2 23.8 25.6 2.1 32.6 38.0 71.3 29.9 38.2 42.3 44.1 20.1 43.7 38.2 32.1 45.0 23.7 34.0 24.4 NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770286-1771730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041113, HPA052733" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" 7900000 Nucleoplasm Cytosol "HPA041113: , HPA052733: " "prognostic favourable (6.81e-5)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.22e-3)" "unprognostic (4.40e-2)" "unprognostic (4.43e-2)" "unprognostic (7.09e-3)" "unprognostic (1.79e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-1)" "unprognostic (6.11e-3)" 20.6 45.6 18.0 12.9 19.8 6.6 20.0 21.9 18.2 16.6 18.0 11.0 31.6 25.7 14.4 19.1 12.9 14.3 21.5 11.8 17.5 16.1 17.7 11.2 17.3 11.3 18.4 15.9 22.1 26.8 15.1 24.1 9.7 14.4 26.9 6.4 13.8 34.3 41.4 15.2 9.2 24.6 14.6 14.1 20.4 17.5 7.2 14.6 5.1 24.1 11.7 8.8 11.5 17.9 19.3 34.1 15.5 25.6 20.1 24.4 20.0 0.7 11.6 0.2 9.5 2.7 1.4 1.1 6.8 2.0 1.2 0.9 0.0 13.8 0.1 18.9 0.9 9.8 0.6 3.8 0.1 13.5 30.8 0.0 5.4 5.5 5.1 2.3 4.3 6.3 3.4 1.2 0.6 2.4 4.6 1.9 1.1 16.8 0.2 4.5 12.3 9.4 6.4 0.1 18.0 2.0 0.5 13.5 10.4 20.4 15.4 1.6 14.7 5.6 8.5 2.5 9.6 8.1 4.6 4.9 1.5 1.0 3.5 0.4 5.8 4.9 25.6 15.5 17.5 22.9 17.1 19.3 24.4 16.4 22.0 16.3 21.4 16.8 5.3 20.1 24.5 34.1 21.8 20.0 18.0 19.8 21.9 18.2 17.5 16.1 18.4 15.9 14.4 14.6 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Mitochondria "CAB045997: AB_11126630, HPA072588: " "unprognostic (3.27e-1)" "prognostic unfavourable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavourable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 34.5 34.4 21.5 13.9 17.6 46.8 34.6 10.4 13.6 25.6 44.6 12.8 40.7 9.7 21.7 33.7 25.1 20.0 39.9 26.9 16.6 16.5 20.2 61.2 13.5 27.5 16.9 11.3 31.9 19.2 22.0 17.3 19.4 11.7 46.9 10.6 32.2 44.4 44.0 13.7 7.5 15.3 83.9 12.4 17.8 27.1 13.3 10.9 19.6 21.0 14.2 14.5 64.1 27.5 13.1 28.6 18.2 6.3 1.2 13.7 5.2 0.1 49.5 44.0 60.4 17.6 31.0 9.8 23.3 28.0 35.3 30.3 33.0 28.8 0.4 17.6 37.1 0.6 23.8 25.0 10.4 19.9 35.5 24.0 6.7 44.0 33.3 17.4 8.8 39.9 13.2 21.6 2.1 22.6 24.8 4.3 26.2 40.5 15.2 22.0 44.8 11.0 76.9 9.8 12.5 24.4 0.2 12.9 69.6 5.9 0.4 21.6 29.4 41.0 28.1 25.2 36.7 16.8 5.8 0.5 0.3 13.1 11.0 3.2 29.0 4.1 6.3 18.2 7.5 5.6 6.5 12.3 7.7 8.3 8.7 13.1 13.7 7.1 2.2 1.2 4.8 28.6 0.4 5.2 21.5 17.6 10.4 13.6 16.6 16.5 16.9 11.3 11.7 10.9 NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles Vesicles "HPA017909: AB_1854530" "unprognostic (7.31e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-3)" "unprognostic (2.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.20e-1)" "prognostic unfavourable (2.17e-7)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "prognostic favourable (3.18e-5)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (9.50e-2)" 11.7 12.2 7.0 14.4 11.0 7.7 13.5 9.2 10.9 12.2 12.0 11.9 14.6 13.5 16.1 13.2 16.1 16.3 8.8 13.7 9.9 6.8 18.0 17.5 11.1 12.9 9.2 10.3 14.5 20.6 12.1 13.3 22.1 8.8 13.2 12.7 13.5 20.8 17.6 20.1 10.3 13.4 13.3 7.1 14.2 13.4 9.0 8.2 12.6 17.5 14.3 15.1 13.9 15.7 26.4 23.5 43.3 22.7 23.0 25.8 14.3 17.8 11.1 15.2 11.0 12.4 16.7 13.6 17.5 13.5 25.8 19.6 18.6 15.7 18.0 9.1 13.6 6.2 13.7 19.3 15.3 21.4 13.2 11.7 14.9 15.1 16.6 14.8 12.6 13.6 21.2 22.8 27.3 13.8 19.6 13.9 9.6 8.5 12.4 6.4 12.8 14.6 7.4 13.3 15.1 12.9 15.4 4.7 8.0 11.9 13.2 15.6 14.7 13.8 12.4 5.1 20.2 12.6 24.9 16.5 22.3 16.2 9.7 19.7 11.3 22.0 20.1 43.3 25.8 20.7 23.6 26.4 24.2 21.9 23.5 24.4 18.7 17.7 22.5 23.0 22.7 21.1 19.4 14.3 7.0 11.0 9.2 10.9 9.9 6.8 9.2 10.3 8.8 8.2 NME7 "CFAP67, FLJ37194, NM23-H7" ENSG00000143156 "NME/NM23 family member 7" Q9Y5B8 1 169132531-169367967 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038014, HPA054289" Uncertain Approved Mitochondria Mitochondria "HPA038014: AB_10673037, HPA054289: " "unprognostic (1.28e-1)" "unprognostic (8.52e-2)" "unprognostic (6.21e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" "unprognostic (7.44e-3)" "prognostic unfavourable (3.24e-5)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (6.63e-2)" "unprognostic (2.67e-2)" "unprognostic (1.12e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" 7.7 12.1 13.5 8.0 22.8 3.7 12.8 14.6 16.8 15.6 11.5 5.5 13.4 4.6 16.0 15.8 8.6 31.1 11.2 8.4 18.9 11.3 13.9 8.6 8.9 6.0 9.5 11.5 17.0 8.1 18.9 39.9 5.6 15.6 9.6 6.7 9.3 5.9 14.3 5.1 4.9 5.5 17.2 9.5 5.2 8.1 17.2 9.6 11.9 15.9 5.8 7.0 10.0 8.2 8.5 5.2 1.7 7.1 9.1 12.0 4.7 10.5 11.3 12.3 9.6 12.4 12.5 4.4 7.3 11.1 13.3 16.9 6.4 16.0 3.1 13.4 6.5 7.4 6.9 15.8 21.8 11.0 5.7 5.6 10.8 6.5 8.5 10.2 3.6 9.1 9.6 13.4 18.2 19.0 5.3 4.3 13.3 3.4 9.2 7.5 12.1 11.6 7.2 13.3 6.8 21.6 3.1 13.3 19.2 11.1 3.3 8.2 11.4 7.4 11.3 8.3 27.5 7.3 17.7 5.2 8.8 6.5 9.1 3.6 8.2 1.4 3.3 1.7 8.3 5.1 10.1 8.5 10.8 8.8 5.2 7.0 9.3 10.6 1.0 9.1 7.1 4.4 12.0 4.7 13.5 22.8 14.6 16.8 18.9 11.3 9.5 11.5 15.6 9.6 NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA059447: " "unprognostic (1.94e-1)" "unprognostic (3.81e-3)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (4.45e-3)" "unprognostic (4.55e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "prognostic favourable (3.85e-14)" "unprognostic (3.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.47e-3)" "unprognostic (5.16e-2)" 7.2 13.2 8.1 7.2 9.0 4.0 8.8 4.1 8.1 8.8 12.8 9.3 11.9 8.9 10.1 8.8 8.7 7.4 7.3 13.9 7.6 6.8 11.5 12.6 5.3 5.6 10.3 8.3 5.1 14.1 10.3 9.3 5.6 13.0 7.0 13.6 10.1 17.7 8.4 29.1 8.1 9.2 8.3 9.0 8.6 7.1 10.7 8.3 6.8 10.8 11.5 6.8 6.2 10.4 5.3 4.3 12.8 4.9 3.1 2.7 2.3 3.7 4.7 6.5 6.3 12.4 11.3 1.5 7.4 6.1 8.7 5.6 2.0 6.5 4.0 4.8 11.3 3.9 7.9 10.6 10.5 8.3 4.0 6.6 2.9 6.1 9.9 5.4 6.5 11.9 12.0 10.5 15.1 9.0 7.7 2.7 9.6 6.4 3.0 3.5 0.8 8.4 3.5 4.0 2.1 10.1 2.1 4.7 2.4 9.8 8.4 8.4 3.1 5.8 8.5 3.6 3.2 7.3 3.4 3.9 3.7 3.9 6.1 11.4 7.3 6.6 4.9 3.9 2.4 3.3 1.1 5.3 2.3 2.7 4.2 3.6 2.1 2.5 12.8 3.1 4.5 4.3 1.9 2.3 8.1 9.0 4.1 8.1 7.6 6.8 10.3 8.3 13.0 8.3 NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418602 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9" "Cell line enhanced" "Detected in many" "HSkMC: 12.7;SCLC-21H: 37.1;U-2197: 21.7;U-87 MG: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061714 Enhanced "HPA061714: " "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" 9.6 7.7 26.2 1.9 34.5 1.0 2.9 53.9 53.5 3.6 2.2 2.0 0.0 1.5 2.5 2.7 1.9 3.8 4.1 19.6 20.6 15.1 1.5 1.1 1.8 1.7 8.6 28.3 1.5 2.9 1.3 17.4 2.0 15.6 1.3 2.1 0.5 1.5 4.1 1.3 1.7 2.0 2.7 4.1 1.2 2.1 8.7 6.3 0.0 7.2 0.0 1.7 1.9 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.2 2.5 0.0 1.5 6.1 2.2 1.6 4.0 0.8 0.2 1.2 2.4 0.0 6.8 0.3 1.0 0.1 0.0 1.6 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 12.7 0.5 1.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.2 4.4 2.4 0.0 0.1 0.0 2.8 2.0 37.1 2.8 0.3 0.1 0.0 0.3 0.6 1.3 1.2 0.4 21.7 1.4 0.3 0.0 0.0 16.9 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 26.2 34.5 53.9 34.7 20.6 15.1 8.6 28.3 15.6 6.3 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA039077, HPA057402" Approved Supported Mitochondria Mitochondria "HPA039077: , HPA057402: " "unprognostic (9.45e-3)" "prognostic favourable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favourable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favourable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 6.2 6.3 9.9 7.0 9.8 14.1 10.8 7.7 9.8 7.4 7.4 6.8 2.7 7.8 7.9 7.3 6.5 11.6 7.9 12.6 11.9 8.1 7.9 6.2 4.7 3.6 7.7 14.0 17.9 10.0 6.2 6.6 1.8 6.7 7.6 6.4 12.7 7.5 4.8 21.9 14.9 6.5 7.3 7.0 4.2 4.8 16.8 8.4 2.4 8.3 9.0 4.8 6.3 6.8 7.2 4.2 11.9 5.0 6.1 5.1 2.1 6.8 2.9 3.3 3.7 0.8 0.7 4.4 2.9 0.3 0.5 0.4 3.9 5.2 4.8 8.7 0.6 3.5 2.2 1.0 0.7 4.3 3.9 22.2 6.3 5.0 1.8 4.2 4.3 1.2 5.8 0.9 1.4 0.4 3.8 10.5 0.5 4.7 3.9 3.7 7.4 2.9 3.5 3.7 3.2 0.9 5.2 7.2 4.4 6.8 3.8 2.5 9.5 11.1 3.9 4.7 10.3 5.6 4.3 17.4 8.3 3.3 3.1 6.7 4.3 11.9 5.0 3.0 4.1 4.5 3.0 3.6 3.6 3.4 3.6 7.2 5.1 5.1 10.8 6.1 4.4 4.2 2.2 2.1 9.9 9.8 7.7 9.8 11.9 8.1 7.7 14.0 6.7 8.4 NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 29.6;Karpas-707: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA049795: " "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (3.58e-2)" "prognostic favourable (3.70e-6)" "unprognostic (3.56e-2)" "unprognostic (2.35e-1)" "unprognostic (5.20e-3)" "unprognostic (2.21e-2)" "unprognostic (3.27e-2)" "unprognostic (2.43e-1)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "prognostic favourable (5.60e-4)" "unprognostic (9.25e-2)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (5.64e-2)" 15.5 7.7 11.1 15.9 10.7 6.9 14.3 21.5 14.6 13.2 15.2 5.8 20.1 12.2 8.1 15.6 24.6 9.4 10.9 9.4 10.2 9.7 22.1 40.3 15.4 19.9 10.8 9.7 15.2 30.6 45.8 18.1 19.7 10.2 15.9 10.3 10.9 29.5 17.7 15.0 15.6 26.6 8.3 8.7 18.8 13.6 6.7 8.9 14.4 31.6 11.2 22.0 12.6 14.8 6.7 8.8 7.3 6.7 8.2 24.2 10.1 5.0 1.1 1.5 3.5 12.1 16.3 8.3 7.4 11.7 1.9 3.0 0.0 13.5 3.0 4.5 7.1 8.9 1.6 5.0 6.0 29.6 1.8 2.1 2.4 2.6 10.8 2.0 0.4 11.3 12.7 3.1 6.4 12.9 0.2 36.5 13.1 3.8 1.9 1.8 1.9 4.7 0.6 13.4 19.2 15.2 9.1 1.0 0.2 3.2 3.3 4.1 8.4 2.1 8.9 6.4 1.2 5.9 2.0 16.2 12.9 1.8 10.5 2.2 6.5 7.3 2.7 4.5 13.9 2.5 16.7 6.7 24.2 16.0 3.1 3.9 22.1 16.7 5.2 8.2 6.7 8.8 15.4 10.1 11.1 10.7 21.5 14.6 10.2 9.7 10.8 9.7 10.2 8.9 NMRK2 "ITGB1BP3, MIBP, NRK2" ENSG00000077009 "Nicotinamide riboside kinase 2" Q9NPI5 19 3933103-3942416 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "heart muscle: 271.6;skeletal muscle: 103.2" "Group enriched" "Detected in some" 7 "BEWO: 22.4;NTERA-2: 18.5" "Cancer enhanced" "Detected in some" "renal cancer: 32.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049909, HPA054792, HPA072450" Approved Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA049909: , HPA054792: , HPA072450: " "unprognostic (3.61e-1)" "unprognostic (5.92e-2)" "unprognostic (1.18e-2)" "unprognostic (2.54e-1)" "unprognostic (1.03e-1)" "unprognostic (7.61e-2)" "unprognostic (3.30e-2)" "prognostic favourable (1.19e-4)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (5.38e-1)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 1.0 0.0 0.0 271.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 1.0 1.9 0.1 103.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 18.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 45051610-45109016 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.8 32.6 44.9 28.2 37.3 12.0 26.1 34.5 64.3 23.7 24.4 17.2 22.9 23.4 27.3 29.3 26.6 30.9 17.3 26.8 37.7 29.6 28.8 36.6 26.7 27.2 27.7 43.6 29.3 21.8 41.6 23.7 32.7 38.1 23.7 23.1 18.1 34.9 30.1 75.5 28.8 24.8 30.1 36.6 28.2 23.4 26.1 34.0 20.7 29.4 18.6 30.9 25.1 43.3 10.2 18.2 7.6 9.3 7.4 10.0 3.3 16.9 22.4 19.4 17.1 35.1 22.7 20.4 18.9 25.0 36.8 30.4 25.0 14.6 20.4 27.4 26.0 16.0 33.3 26.5 34.2 51.8 23.2 20.3 15.0 24.7 23.1 26.1 24.5 28.6 24.1 27.4 21.8 24.7 32.2 10.4 20.5 14.5 31.7 17.8 18.1 23.5 21.7 28.9 15.5 29.1 15.7 16.2 14.6 11.9 10.9 17.1 23.6 20.7 19.8 22.5 17.3 18.1 25.1 16.1 22.8 20.4 24.1 14.7 23.8 6.5 8.1 7.6 7.9 9.3 7.2 10.2 7.8 9.3 6.6 7.6 10.0 7.6 5.3 7.4 6.9 18.2 7.5 3.3 44.9 37.3 34.5 64.3 37.7 29.6 27.7 43.6 38.1 34.0 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 33.5;HMC-1: 28.0;TIME: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 8.7;eosinophil: 7.9;gdT-cell: 7.2;MAIT T-cell: 12.9;memory CD4 T-cell: 11.5;memory CD8 T-cell: 8.3;naive CD4 T-cell: 14.7;naive CD8 T-cell: 9.3;NK-cell: 12.9;T-reg: 17.5" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;NK-cells: 12.9;T-cells: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 29.3 5.4 18.9 6.5 17.3 3.8 19.2 35.6 25.3 12.0 9.9 6.0 4.7 7.4 14.5 5.0 8.2 8.9 8.1 9.6 12.8 9.2 10.8 18.5 7.2 9.0 8.8 15.0 18.2 7.1 28.5 7.9 5.1 10.3 10.7 10.7 8.3 5.8 9.4 18.8 11.5 11.9 12.5 10.3 10.1 8.8 14.5 9.9 23.7 6.9 4.5 8.9 10.1 20.1 1.9 0.3 8.7 0.5 12.9 17.5 3.9 2.7 3.6 4.1 3.1 11.4 12.3 0.8 6.1 5.0 5.6 7.7 3.5 12.6 0.1 4.3 33.5 3.5 3.7 3.4 9.6 3.7 4.8 7.5 1.7 4.7 7.6 0.5 28.0 10.9 3.6 8.0 2.4 21.8 3.5 0.5 21.0 3.4 5.7 1.4 3.0 3.5 4.3 6.1 0.5 4.2 0.6 1.2 4.8 7.4 1.2 2.0 3.8 2.3 48.6 5.6 8.3 24.8 4.4 4.3 4.5 0.3 6.9 2.0 4.1 8.7 0.3 7.9 7.2 0.4 12.9 1.4 11.5 8.3 0.3 1.9 14.7 9.3 1.2 12.9 0.5 0.2 17.5 3.9 18.9 17.3 35.6 25.3 12.8 9.2 8.8 15.0 10.3 9.9 NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313285 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 97.7" "Cell line enhanced" "Detected in many" "HSkMC: 67.4;LHCN-M2: 40.0;RPTEC TERT1: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" 15000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA059180: " "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavourable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (1.02e-6)" "prognostic unfavourable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" 23.7 1.4 0.6 8.8 0.9 0.1 14.6 0.6 1.7 13.1 8.5 0.7 4.9 0.5 15.8 8.7 12.0 8.3 15.3 8.2 1.6 0.0 4.7 97.7 10.0 3.4 1.1 0.6 11.2 2.0 0.6 2.6 8.6 3.3 9.6 3.3 1.6 3.6 6.7 18.3 8.2 4.3 12.4 1.5 5.8 5.1 7.3 0.6 1.3 5.3 2.2 3.1 10.9 35.3 0.6 0.1 0.7 0.2 0.0 0.9 0.0 0.0 4.7 0.0 4.2 24.3 31.6 0.0 6.0 15.9 9.6 19.1 0.0 6.5 0.0 21.4 12.2 0.0 0.0 2.1 9.7 0.0 0.0 0.0 7.4 0.0 33.1 0.0 0.0 67.4 23.3 6.8 10.1 13.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.1 0.0 26.8 0.0 103.7 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 9.3 5.5 22.1 8.5 1.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.9 0.2 0.0 0.2 0.1 0.6 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.6 0.9 0.6 1.7 1.6 0.0 1.1 0.6 3.3 0.6 NOSIP CGI-25 ENSG00000142546 "Nitric oxide synthase interacting protein" Q9Y314 19 49555711-49590262 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 119.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043464, HPA062132" Approved Enhanced Nucleoplasm Nucleoplasm "HPA043464: AB_10794284, HPA062132: AB_2684693" "unprognostic (2.27e-1)" "unprognostic (4.69e-2)" "unprognostic (1.39e-1)" "unprognostic (4.17e-2)" "unprognostic (1.59e-2)" "unprognostic (9.46e-2)" "unprognostic (1.47e-2)" "unprognostic (9.42e-2)" "unprognostic (3.79e-1)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (9.73e-2)" "unprognostic (3.97e-2)" "unprognostic (2.15e-1)" "unprognostic (9.76e-2)" "unprognostic (1.02e-1)" "unprognostic (2.95e-3)" 13.4 13.9 14.2 14.0 14.0 14.3 11.5 12.1 14.2 11.3 15.9 12.3 13.1 17.3 12.5 8.1 12.7 11.1 11.7 14.9 12.3 11.4 13.2 14.5 12.6 24.6 18.3 10.8 12.9 39.7 7.1 13.6 15.6 14.3 11.6 7.9 11.3 19.2 11.4 66.9 11.9 16.5 11.0 13.1 18.0 13.9 40.2 16.3 20.6 15.5 17.6 16.3 11.7 15.0 20.4 21.5 31.8 16.8 29.7 119.4 69.2 66.1 35.9 14.0 30.9 12.5 9.2 13.5 15.7 13.9 26.3 24.3 25.0 11.7 17.8 27.5 13.1 14.9 13.8 27.5 11.5 20.3 39.7 22.5 20.7 27.8 19.8 18.2 19.0 11.9 19.1 20.0 10.9 15.9 24.9 14.2 13.7 17.7 18.5 39.2 19.0 31.2 24.2 23.3 15.8 12.2 20.0 17.5 22.8 21.1 18.0 15.7 14.7 19.3 23.4 22.9 19.4 7.9 29.9 26.8 50.5 24.1 8.7 25.1 17.7 28.0 16.8 23.5 35.1 15.7 45.4 20.4 71.4 40.2 16.6 19.8 119.4 65.8 31.8 29.7 14.3 21.5 37.5 69.2 14.2 14.0 12.1 14.2 12.3 11.4 18.3 10.8 14.3 16.3 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822543-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 42.2;placenta: 64.8" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 32.4;HSkMC: 6.2;RH-30: 7.3;RPTEC TERT1: 19.9" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 10 "cerebellum: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 28 "cerebellum: 16.0" "Low region specificity" "Detected in many" HPA017238 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 2.6 12.7 0.4 2.7 0.4 0.0 0.8 4.3 0.3 3.5 1.5 0.1 4.6 0.0 4.3 15.6 1.6 1.3 7.5 2.9 0.4 0.4 9.9 0.4 0.5 0.0 0.3 0.0 42.2 0.5 0.0 2.9 64.8 0.2 22.0 0.1 0.0 2.1 1.6 0.4 0.4 0.5 2.8 0.4 0.3 0.9 10.6 0.0 0.0 0.5 3.1 0.3 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 6.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 7.3 0.0 19.9 0.4 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 4.3 0.3 0.4 0.4 0.3 0.0 0.2 0.0 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300215 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA048431: , HPA070333: , HPA073705: " "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 11.8 13.2 11.9 25.4 15.7 23.9 14.0 28.9 16.7 15.6 14.2 18.5 17.0 10.6 19.0 13.9 17.8 13.6 15.8 11.7 12.8 11.5 14.4 10.5 12.3 19.4 12.9 11.7 16.6 27.1 24.6 19.3 16.0 13.4 14.2 14.3 13.8 13.5 18.7 20.6 16.1 14.5 15.6 13.2 16.1 13.1 28.1 16.1 27.3 20.1 10.6 22.7 13.4 20.2 10.2 8.9 18.7 10.8 10.9 7.8 2.9 9.7 12.6 13.1 11.3 6.4 8.3 0.4 8.8 8.9 12.4 11.6 2.8 8.2 20.1 10.0 12.1 8.4 20.8 19.6 15.1 34.0 12.6 8.9 14.2 0.1 10.7 19.2 10.6 7.8 11.9 14.7 13.8 18.0 12.1 7.1 12.5 20.4 13.3 6.2 14.2 11.1 14.8 1.7 6.2 8.0 11.8 15.9 11.0 22.9 10.0 6.9 10.0 16.0 13.3 8.7 12.6 5.5 10.9 8.3 7.2 14.4 5.0 9.4 9.3 10.7 9.1 9.4 7.5 6.1 6.3 8.5 6.3 5.0 6.7 10.2 7.8 6.3 18.7 10.9 10.8 8.9 5.7 2.9 11.9 15.7 28.9 16.7 12.8 11.5 12.9 11.7 13.4 16.1 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871424-1982207 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm Nucleoplasm "CAB068246: , CAB068247: , HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavourable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavourable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 8.7 7.6 17.6 11.5 16.2 35.1 8.5 20.6 18.2 7.0 14.8 12.4 6.3 14.0 9.5 7.4 12.7 6.8 6.9 11.9 15.1 10.9 8.4 7.5 11.1 18.8 14.7 16.1 7.0 11.7 10.7 11.8 9.8 14.6 8.7 17.7 9.4 10.2 7.4 11.8 12.1 14.6 10.5 15.3 13.5 11.0 26.3 13.4 46.7 13.8 5.5 17.7 8.6 9.4 4.9 3.9 4.1 1.8 2.7 4.3 0.6 27.4 13.9 41.9 18.3 4.5 6.7 12.2 22.2 19.7 27.2 30.5 12.2 32.6 29.6 7.6 18.3 12.0 27.0 18.3 46.8 14.2 11.1 35.2 19.2 7.2 5.7 21.5 18.5 2.6 4.6 23.9 23.0 21.4 19.0 31.1 22.3 10.8 57.5 22.6 17.6 16.0 32.9 27.3 10.2 11.2 13.0 26.0 20.8 18.2 6.8 8.3 16.1 14.5 16.5 27.2 20.3 17.2 44.6 14.6 15.4 26.8 16.3 21.4 25.2 2.1 1.7 1.7 2.9 1.8 3.2 1.8 3.2 3.2 1.5 4.9 2.8 2.3 4.1 2.7 1.4 3.9 4.3 0.6 17.6 16.2 20.6 18.2 15.1 10.9 14.7 16.1 14.6 13.4 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269697-38382272 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavourable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 19.2 11.3 31.1 15.8 31.4 36.3 20.1 51.5 37.7 18.5 15.5 16.7 14.0 16.2 16.0 12.5 17.0 16.8 17.0 12.7 24.4 16.6 14.2 11.2 17.9 22.3 25.0 26.8 26.5 16.3 21.0 24.2 22.5 21.9 16.4 18.7 12.3 18.3 17.9 12.3 16.2 17.7 16.0 15.3 17.2 19.7 9.3 25.6 16.7 19.2 6.9 20.4 19.6 23.3 26.7 5.6 26.2 5.1 8.6 18.0 2.9 23.9 13.8 23.7 16.0 16.6 19.2 17.6 20.1 22.3 17.4 20.3 7.3 13.3 28.6 18.5 13.7 14.4 18.7 16.1 24.9 11.3 11.0 36.4 11.1 8.6 17.1 16.0 13.2 10.3 16.4 15.7 32.1 20.0 25.8 19.0 16.5 8.6 46.7 13.6 16.1 6.5 21.4 25.9 9.0 12.4 18.6 13.4 18.1 16.3 14.3 14.0 18.1 12.2 19.0 18.2 18.9 27.0 11.8 17.0 20.2 27.6 15.3 16.2 13.1 13.9 5.1 9.1 8.0 2.4 5.3 16.5 12.0 7.1 4.1 26.7 15.0 6.3 26.2 8.6 1.5 5.6 18.0 2.9 31.1 31.4 51.5 37.7 24.4 16.6 25.0 26.8 21.9 25.6 NSMCE1 NSE1 ENSG00000169189 "NSE1 homolog, SMC5-SMC6 complex component" Q8WV22 16 27224991-27268794 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041567, HPA043091" Supported Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA041567: AB_10964260, HPA043091: AB_10962722" "unprognostic (6.27e-2)" "unprognostic (8.17e-2)" "unprognostic (2.52e-2)" "unprognostic (2.48e-3)" "unprognostic (4.17e-1)" "unprognostic (4.52e-3)" "unprognostic (1.59e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-3)" "unprognostic (3.58e-1)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 24.0 37.3 26.7 33.3 27.4 16.9 30.1 16.9 27.2 22.2 24.7 31.4 30.8 14.1 23.1 32.5 34.7 36.0 36.7 21.7 24.3 26.3 30.9 37.4 27.1 36.7 31.9 20.9 29.5 45.3 46.7 20.5 21.4 27.1 33.8 21.2 26.0 37.2 31.5 22.5 19.5 23.8 35.4 32.4 20.9 26.2 55.4 19.3 41.5 33.9 25.7 29.3 27.6 20.4 42.0 38.9 31.8 27.7 60.4 41.6 32.6 14.4 20.8 14.3 15.5 23.2 31.2 11.5 15.5 15.8 11.8 12.3 16.1 35.3 28.5 37.2 23.5 15.6 26.7 46.4 15.3 34.8 18.5 13.1 19.3 30.8 40.5 15.3 9.9 30.5 32.4 29.6 56.7 15.8 17.5 9.0 21.7 24.4 20.0 17.0 12.6 14.4 17.6 17.6 44.5 34.1 9.4 15.1 13.7 10.5 14.7 26.4 24.3 18.4 9.8 14.3 9.0 16.3 14.8 27.0 19.4 21.9 30.8 15.2 6.1 31.8 27.7 25.0 25.2 24.3 27.8 24.1 36.0 30.6 38.9 42.0 41.6 32.6 9.0 60.4 22.5 37.7 32.8 32.6 26.7 27.4 16.9 27.2 24.3 26.3 31.9 20.9 27.1 19.3 NSUN2 "FLJ20303, Misu, MRT5, TRM4" ENSG00000037474 "NOP2/Sun RNA methyltransferase family member 2" Q08J23 5 6599239-6633291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037896 Supported Approved Nucleoplasm Nucleoplasm "HPA037896: AB_10670532" "unprognostic (3.99e-2)" "unprognostic (5.73e-2)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (8.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.44e-3)" "unprognostic (5.12e-2)" "unprognostic (4.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (2.48e-2)" "prognostic unfavourable (5.69e-5)" "unprognostic (1.98e-1)" "unprognostic (1.47e-1)" "unprognostic (4.30e-3)" "unprognostic (1.70e-2)" 19.0 19.1 11.3 20.4 17.4 16.7 28.1 13.4 16.0 17.4 17.9 20.2 18.2 15.4 21.5 20.6 27.0 19.3 17.1 20.1 12.7 9.7 15.0 34.9 15.0 22.5 13.6 16.5 17.2 18.7 19.5 22.3 18.2 16.1 15.5 21.2 14.3 20.0 15.8 42.3 22.9 20.9 19.1 15.9 23.7 19.9 15.8 13.2 26.7 14.3 17.1 29.5 19.2 17.1 18.1 16.7 15.6 17.3 17.6 22.7 12.7 26.9 23.4 13.8 12.1 8.8 9.8 32.5 21.1 12.8 22.5 19.6 30.4 20.2 46.5 21.6 16.9 20.7 28.5 24.6 30.6 31.7 23.0 27.7 55.5 17.6 12.6 47.7 22.4 11.2 18.2 25.5 22.3 15.9 35.7 17.1 20.8 18.8 26.0 20.7 22.8 30.6 34.0 14.5 14.3 15.8 30.0 13.2 18.6 52.2 26.5 20.3 23.1 21.3 18.5 18.0 23.7 18.6 31.4 14.1 26.5 44.6 14.4 38.0 20.6 9.7 14.6 15.6 17.5 17.3 22.7 18.1 18.4 20.7 16.7 16.5 20.4 20.6 2.9 17.6 15.2 16.5 13.0 12.7 11.3 17.4 13.4 16.0 12.7 9.7 13.6 16.5 16.1 13.2 NTMT1 "AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1" ENSG00000148335 "N-terminal Xaa-Pro-Lys N-methyltransferase 1" Q9BV86 9 129608884-129636131 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020092, HPA058420" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA020092: AB_1853831, HPA058420: " "unprognostic (4.74e-3)" "unprognostic (1.77e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (4.17e-3)" "unprognostic (4.92e-2)" "unprognostic (1.24e-1)" "unprognostic (8.57e-2)" "unprognostic (3.63e-1)" "unprognostic (4.35e-2)" "unprognostic (1.00e-3)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (3.50e-3)" 10.2 25.7 11.9 11.5 13.1 13.8 10.0 13.2 15.3 8.9 10.7 9.0 14.4 11.7 8.8 13.6 10.2 7.8 16.6 31.8 11.5 11.5 11.7 16.8 8.9 11.5 15.7 11.3 8.8 19.5 9.4 10.8 12.1 13.8 10.2 7.4 9.4 13.0 11.4 54.6 10.7 10.2 13.6 10.3 13.1 10.5 56.2 10.7 10.8 12.3 22.1 9.8 12.3 14.5 27.1 28.4 20.3 34.2 14.8 26.6 19.4 16.6 34.5 14.3 24.2 9.1 13.6 15.4 31.7 18.8 32.1 27.8 28.3 21.9 21.4 16.3 22.6 32.5 30.0 27.9 20.2 16.5 16.1 8.9 31.1 28.5 29.3 18.0 13.6 14.5 14.2 33.6 16.8 17.5 32.8 16.1 16.7 55.1 20.3 24.3 18.7 30.2 19.3 16.9 43.0 12.9 9.5 29.1 15.2 15.6 29.3 21.6 24.4 9.4 11.8 38.6 19.6 35.8 33.2 12.7 15.1 32.6 17.6 18.7 22.1 15.1 27.3 20.3 25.2 28.7 24.8 23.4 25.5 26.6 26.4 27.1 26.4 22.0 7.6 14.8 34.2 28.4 23.4 19.4 11.9 13.1 13.2 15.3 11.5 11.5 15.7 11.3 13.8 10.7 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 15.8;blood: 32.3;brain: 28.3" "Cell line enriched" "Detected in some" 4 "HMC-1: 41.1" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enriched" "Detected in many" 5 "pons and medulla: 28.3" "Cell type enriched" "Detected in single" 127 "basophil: 32.3" "Lineage enriched" "Detected in single" 323 "granulocytes: 32.3" "Region enhanced" "Detected in some" "basal ganglia: 8.2" "Low region specificity" "Detected in all" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol 140000 "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: , HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 1.0 15.8 0.5 0.8 6.0 0.9 0.4 0.0 0.7 0.9 1.1 0.1 0.0 0.8 1.6 2.0 0.7 0.6 2.1 1.5 0.0 1.2 2.9 0.2 1.9 0.3 2.1 0.6 0.3 0.3 0.3 1.1 0.5 28.3 2.2 0.2 3.1 1.2 0.5 0.7 0.2 0.4 1.1 1.2 0.2 1.0 2.4 1.5 0.4 0.3 0.0 0.4 0.7 0.8 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.6 0.0 6.6 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 1.1 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.7 9.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 32.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.0 0.0 0.6 0.0 1.2 2.1 0.6 28.3 1.5 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027070 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Epilepsy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;thyroid gland: 63.4" "Cell line enhanced" "Detected in some" "AF22: 10.4;HaCaT: 3.7;RPTEC TERT1: 11.6;SH-SY5Y: 13.3" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346" Enhanced Approved Cytosol 13000000 Cytosol "CAB010346: AB_2155274, HPA007637: AB_1080385" "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 19.8 2.7 66.1 2.0 56.7 1.2 33.2 15.1 133.8 6.4 4.4 27.4 0.0 1.4 3.0 3.3 5.6 3.7 18.7 5.8 61.0 30.7 12.5 2.1 6.3 2.7 32.4 41.4 6.6 18.9 1.6 3.0 2.1 34.1 3.8 3.1 2.0 8.6 11.9 2.0 7.2 1.6 3.0 22.1 6.5 1.4 2.4 34.1 0.0 63.4 2.6 3.4 3.5 3.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.6 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.8 0.9 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 66.1 56.7 15.1 45.6 61.0 30.7 32.4 41.4 34.1 34.1 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8" "Cell line enriched" "Detected in some" 8 "U-138 MG: 47.4" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli" 11000000 Nucleoli "Nuclear membrane" "CAB009233: AB_632555, HPA027484: , HPA048065: " "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 20.8 7.4 22.0 2.5 28.1 1.5 6.2 30.4 41.8 7.0 4.0 8.4 1.3 2.0 12.4 6.7 3.4 9.5 3.9 5.5 22.0 11.1 5.1 2.0 5.7 3.1 11.2 18.7 5.1 2.9 1.6 7.9 2.8 14.7 6.8 4.7 8.0 11.5 8.7 1.9 2.9 2.5 7.7 13.7 4.1 3.0 13.8 13.7 0.0 2.5 0.7 4.3 7.1 4.8 0.7 0.4 1.3 0.5 0.5 0.8 0.0 0.0 5.9 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.9 0.0 0.5 0.0 0.0 0.0 1.4 0.0 0.1 1.2 0.5 0.4 0.3 0.1 0.2 0.4 0.3 0.3 0.1 0.7 0.4 0.4 1.3 0.5 0.1 0.4 0.8 0.0 22.0 28.1 30.4 28.9 22.0 11.1 11.2 18.7 14.7 13.7 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell line enhanced" "Detected in many" "AF22: 23.0;EFO-21: 23.0;Karpas-707: 16.8;RH-30: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: " "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavourable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 3.4 23.0 0.2 9.2 1.0 10.6 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.0 10.3 4.8 4.8 4.6 2.0 0.0 1.3 0.0 3.6 1.8 1.9 0.0 0.0 4.7 3.1 2.5 0.8 8.3 0.0 16.8 3.1 0.5 0.1 0.2 4.5 1.4 0.0 33.0 4.0 2.5 5.9 2.7 0.1 2.6 0.7 0.2 1.2 0.1 6.2 3.8 12.8 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell line enhanced" "Detected in many" "BEWO: 24.3;CACO-2: 12.9;RPMI-8226: 18.7;RPTEC TERT1: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favourable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.2 12.3 7.5 0.3 0.2 0.3 24.3 2.9 3.0 8.1 3.3 12.9 0.4 3.7 1.8 0.8 4.5 1.7 4.4 3.5 0.0 0.2 0.0 0.7 2.2 5.2 0.0 0.0 1.4 3.3 4.7 2.8 0.3 0.5 0.9 1.5 0.5 0.0 0.0 4.8 0.4 0.0 0.5 18.7 22.2 0.0 1.1 0.1 0.8 3.5 0.3 3.6 0.0 0.9 2.9 1.4 0.3 4.6 6.6 1.0 2.3 0.4 0.0 1.1 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165325-12196144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome 660000 Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavourable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 19.6 22.0 17.4 18.6 21.2 13.5 20.2 15.4 21.4 16.7 20.4 16.1 15.2 17.3 10.0 16.5 25.8 16.3 12.1 10.0 16.2 14.3 26.0 57.1 16.8 22.7 21.7 12.8 12.5 16.9 19.1 35.7 19.9 18.5 13.4 24.2 13.2 16.7 19.7 5.1 20.6 15.9 11.6 17.9 22.4 14.1 8.0 21.5 28.2 19.1 16.5 29.5 16.2 18.6 22.4 45.9 50.1 19.5 16.2 37.0 20.4 37.3 27.6 33.0 30.7 32.0 31.6 29.3 27.7 17.7 32.7 35.1 39.6 35.7 37.4 24.1 22.4 37.6 46.0 42.9 30.0 30.6 45.0 31.1 33.9 58.1 33.4 20.6 21.9 33.2 25.6 35.6 18.2 41.6 41.6 25.6 29.7 34.3 38.6 24.2 28.7 17.2 35.3 12.0 43.4 30.5 12.9 15.9 23.9 33.6 25.9 38.5 44.4 21.3 26.0 13.9 26.7 38.8 33.8 21.6 37.9 50.3 29.3 26.9 10.3 8.1 19.1 33.5 22.8 19.5 26.2 22.4 24.6 26.8 27.0 18.3 17.0 23.0 50.1 16.2 14.8 45.9 37.0 20.4 17.4 21.2 15.4 21.4 16.2 14.3 21.7 12.8 18.5 21.5 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675502-117710640 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavourable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 8.4 10.2 14.7 9.3 14.7 7.0 10.0 8.8 13.4 29.6 9.2 6.8 2.0 7.1 9.6 13.5 9.5 8.8 7.1 8.2 12.7 9.9 13.1 17.4 9.5 8.4 16.4 15.7 8.8 28.9 15.0 20.0 10.6 16.2 9.6 9.3 7.1 13.8 14.9 7.9 6.1 14.4 8.5 7.3 9.1 10.6 5.6 12.2 7.2 16.5 3.1 8.7 9.1 18.0 2.4 8.1 3.3 4.9 4.1 4.5 2.3 10.0 7.4 16.1 18.0 16.3 21.4 39.6 18.5 19.3 15.5 17.9 16.8 11.3 23.9 20.1 17.0 9.2 23.9 18.1 28.9 17.9 22.0 27.3 12.5 30.1 25.1 34.4 16.1 18.7 20.6 16.9 34.7 15.9 32.6 21.3 23.1 11.4 16.1 21.9 18.7 13.6 15.6 11.6 17.1 30.7 10.1 19.1 15.1 11.1 14.5 13.6 9.2 36.1 13.9 9.6 11.9 15.3 26.5 29.6 22.1 25.4 22.7 26.5 19.1 3.3 3.0 1.8 3.1 3.0 4.5 2.4 3.7 4.1 3.2 2.1 3.1 4.0 0.2 4.1 4.9 8.1 3.4 2.3 14.7 14.7 8.8 13.4 12.7 9.9 16.4 15.7 16.2 12.2 OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112906777-112933222 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 83.9" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 51.4;BJ hTERT+ SV40 Large T+ RasG12V: 73.9;U-266/70: 72.5;U-266/84: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 83.9" "Low lineage specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favourable (6.12e-6)" 31.2 7.3 6.1 16.6 7.1 5.7 8.4 2.1 6.0 16.4 25.4 11.0 2.6 23.6 5.8 21.0 39.1 5.1 10.7 5.1 4.2 5.7 18.3 23.3 20.7 17.3 5.9 5.3 7.4 3.2 4.3 6.1 18.8 8.6 11.5 20.5 11.7 31.8 4.2 2.9 6.3 27.2 7.6 9.4 30.1 22.7 4.2 6.2 21.6 9.4 13.5 27.3 20.9 13.0 18.2 24.4 4.1 83.9 4.5 16.8 29.0 1.0 5.8 0.0 0.0 2.0 1.6 0.4 0.0 7.6 51.4 73.9 3.3 6.2 8.0 2.3 0.0 2.6 0.0 0.7 0.7 5.9 0.0 0.2 10.5 1.3 0.6 0.1 0.4 0.1 2.2 1.9 0.0 2.7 0.0 3.5 0.0 0.1 0.2 3.6 0.3 5.1 1.7 0.0 3.3 2.6 16.6 0.1 0.3 0.8 1.0 19.6 0.2 1.3 10.1 0.0 0.1 0.7 0.1 72.5 55.0 5.5 0.6 2.3 0.4 1.0 40.9 0.5 4.9 63.6 4.6 18.2 6.5 6.1 24.4 13.6 2.5 3.3 4.1 4.5 83.9 22.1 16.8 29.0 6.1 7.1 2.1 6.0 4.2 5.7 5.9 5.3 8.6 6.2 OAS2 ENSG00000111335 "2'-5'-oligoadenylate synthetase 2" P29728 12 112978395-113011723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 70.9;BJ hTERT+ SV40 Large T+ RasG12V: 57.8;SK-MEL-30: 27.7;U-266/70: 25.8;U-266/84: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA003320, CAB024984" Approved Approved Centrosome Centrosome "CAB024984: , HPA003320: " "unprognostic (2.39e-1)" "unprognostic (9.51e-2)" "unprognostic (2.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.34e-1)" "unprognostic (7.94e-2)" "unprognostic (4.79e-2)" "unprognostic (2.05e-2)" "unprognostic (1.31e-1)" "unprognostic (7.64e-3)" "prognostic unfavourable (4.63e-4)" "unprognostic (4.20e-1)" "prognostic unfavourable (4.31e-6)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.94e-2)" 37.9 3.8 4.0 13.9 5.1 9.0 7.2 1.8 4.9 8.5 4.3 7.5 1.2 4.6 9.0 6.9 13.2 3.9 9.6 6.9 3.8 4.4 8.8 9.9 15.6 24.1 5.0 3.7 3.9 1.9 1.2 2.9 22.2 7.3 6.6 4.7 6.9 32.9 1.8 2.2 2.9 8.8 6.4 7.1 36.6 9.7 2.2 3.0 32.4 9.8 8.2 27.4 13.7 5.4 12.0 12.7 2.0 26.8 15.1 17.4 13.2 0.7 0.1 0.0 0.0 0.3 2.6 0.0 0.1 8.0 70.9 57.8 0.1 1.2 17.8 1.7 1.5 0.8 0.1 0.2 2.5 4.4 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 1.3 4.0 0.0 1.1 0.0 9.3 0.0 0.3 0.5 1.0 0.0 2.5 3.8 0.0 2.7 0.0 6.3 0.0 0.0 0.7 0.2 27.7 0.6 1.1 1.8 0.1 0.0 0.3 0.0 25.8 22.2 2.8 0.6 0.9 0.6 2.0 15.9 1.2 13.4 26.8 16.8 12.0 15.4 15.2 12.7 8.9 15.2 11.2 1.8 15.1 26.0 5.3 17.4 13.2 4.0 5.1 1.8 4.9 3.8 4.4 5.0 3.7 7.3 3.0 OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938352-112973249 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 64.0;BJ hTERT+ SV40 Large T+ RasG12V: 70.0;RT4: 17.5;U-266/84: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" 21000 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: AB_10794990, HPA041372: AB_10795590" "unprognostic (8.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.27e-2)" "unprognostic (4.39e-3)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.14e-3)" "unprognostic (8.06e-3)" "unprognostic (3.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.29e-3)" "unprognostic (2.48e-1)" "prognostic unfavourable (2.23e-5)" "unprognostic (4.25e-2)" "unprognostic (1.37e-2)" "unprognostic (3.29e-2)" "unprognostic (2.93e-2)" 36.9 4.9 5.1 11.2 5.4 18.3 7.0 2.9 5.5 10.5 6.8 5.5 3.2 7.3 10.0 11.8 17.9 4.2 9.4 6.7 4.5 5.3 10.3 7.1 19.9 13.3 5.1 5.1 6.1 3.2 3.3 4.6 19.3 8.7 5.6 6.9 8.9 24.7 3.4 3.3 6.0 9.3 8.3 6.2 22.0 9.5 3.0 3.3 21.3 9.9 6.7 13.5 9.9 8.2 2.6 4.8 10.1 14.7 5.0 3.8 3.9 6.3 9.5 0.0 1.5 0.3 1.4 0.8 1.2 8.3 64.0 70.0 7.2 5.8 0.4 2.3 2.9 5.4 1.2 7.7 5.4 4.7 0.3 4.9 4.4 2.3 1.2 1.7 2.7 0.5 2.5 9.1 0.5 3.3 0.1 1.0 0.8 4.1 2.7 0.9 0.5 5.5 3.9 3.4 0.1 3.0 17.5 0.2 0.0 5.8 2.2 5.7 7.6 0.5 2.2 1.7 1.2 1.5 2.6 0.5 19.1 0.1 1.4 4.8 5.2 0.9 7.9 1.6 2.0 8.6 2.5 2.6 3.0 3.0 4.8 1.3 2.2 2.6 10.1 5.0 14.7 0.2 3.8 3.9 5.1 5.4 2.9 5.5 4.5 5.3 5.1 5.1 8.7 3.3 OAT HOGA ENSG00000065154 "Ornithine aminotransferase" P04181 10 124397303-124418976 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 208.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033576, HPA040098, HPA064742" Enhanced Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB033576: AB_2298892, HPA040098: AB_10793955, HPA064742: " "unprognostic (1.61e-2)" "unprognostic (1.70e-2)" "unprognostic (9.96e-2)" "unprognostic (1.02e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (4.43e-3)" "unprognostic (1.65e-1)" "unprognostic (2.37e-2)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.21e-1)" "unprognostic (2.19e-1)" "unprognostic (2.72e-2)" "unprognostic (2.00e-2)" 13.5 37.1 25.9 9.1 26.7 20.3 33.8 17.2 39.8 24.7 71.9 22.8 33.9 164.0 21.6 15.5 26.1 14.9 16.0 12.7 25.6 29.8 25.6 36.8 11.6 9.3 27.9 30.1 21.8 12.3 12.1 18.0 14.8 37.8 17.9 15.8 13.3 55.2 29.1 13.7 16.3 208.5 22.5 25.5 8.4 17.3 14.6 19.4 4.9 15.9 23.1 15.2 15.5 18.2 10.2 26.5 23.0 23.6 9.6 20.1 16.3 41.4 7.5 4.9 17.6 50.3 48.5 16.8 25.1 51.3 22.5 24.7 19.2 5.4 0.0 18.3 42.4 44.2 22.5 47.0 24.5 7.3 31.2 46.4 5.3 14.3 25.9 0.0 30.6 31.7 24.3 20.2 23.6 26.1 79.8 8.9 31.3 10.7 12.2 2.6 9.8 10.6 11.4 18.8 11.2 21.5 0.6 10.3 11.0 15.8 42.1 35.3 14.0 11.4 20.1 12.8 12.0 21.2 15.6 7.6 8.0 11.2 17.7 12.5 6.1 18.6 23.6 20.7 18.5 20.7 20.1 9.6 15.6 19.4 26.5 10.2 19.6 19.1 23.0 9.6 20.8 5.7 14.4 16.3 25.9 26.7 17.2 39.8 25.6 29.8 27.9 30.1 37.8 19.4 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208130-228378874 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 180.2;tongue: 48.4" "Cell line enhanced" "Detected in many" "HeLa: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavourable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 2.5 0.9 0.5 0.9 4.4 0.6 0.7 3.1 0.6 0.6 0.8 0.5 0.5 0.6 0.8 4.4 2.4 1.0 0.6 21.2 0.5 0.7 1.6 0.5 1.0 1.0 0.5 0.5 1.7 1.4 0.4 2.4 0.5 0.9 1.7 0.3 5.2 2.6 1.1 180.2 1.1 0.8 0.5 0.6 1.4 0.5 0.7 0.6 0.5 2.2 48.4 3.5 0.6 0.7 1.0 1.1 0.1 0.4 0.6 3.2 0.7 2.9 2.8 8.0 4.5 0.2 0.1 5.6 1.5 0.5 1.0 0.9 2.0 2.1 5.7 8.1 0.5 1.0 0.4 1.1 0.2 2.1 5.1 1.9 16.0 0.0 2.0 1.3 6.1 3.0 1.0 0.4 0.2 0.4 5.3 1.3 0.3 5.0 2.0 1.6 8.8 1.7 8.1 0.1 1.3 4.6 1.5 3.0 9.0 0.2 2.9 1.1 8.0 3.7 0.7 0.0 9.3 0.2 0.1 4.7 0.9 1.4 0.0 0.8 2.1 0.1 0.4 0.0 0.9 0.1 0.9 0.5 0.9 0.7 0.9 1.0 3.2 0.5 0.1 0.6 0.1 1.1 0.8 0.7 0.5 4.4 3.1 0.6 0.5 0.7 0.5 0.5 0.9 0.6 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533083-71575897 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: " "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavourable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favourable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavourable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favourable (6.85e-7)" 26.1 24.0 33.3 39.7 36.6 38.7 33.7 75.7 43.8 25.0 23.0 22.0 31.1 22.5 36.7 48.3 24.3 33.4 21.2 25.1 29.3 15.4 27.4 20.3 31.0 47.9 30.2 25.6 42.8 46.1 26.5 34.5 19.5 26.6 34.2 30.3 29.9 35.9 30.9 35.0 45.4 38.4 31.1 32.3 56.7 28.2 11.8 36.6 35.7 34.1 27.6 41.4 24.9 31.0 9.7 7.6 3.2 7.2 12.5 9.9 6.0 14.3 13.5 17.5 15.3 18.9 17.4 11.8 11.0 19.9 12.0 18.5 14.2 16.5 17.1 7.8 13.5 17.9 19.1 10.8 14.8 14.6 19.6 10.8 32.1 10.1 14.3 22.2 17.9 16.6 22.0 13.1 24.8 11.1 10.9 59.5 11.4 12.2 17.1 26.7 11.6 18.4 17.0 19.6 21.9 18.5 16.7 9.0 7.9 17.1 11.4 10.6 8.4 15.1 12.9 13.0 10.6 13.5 6.4 16.3 11.7 20.6 9.1 23.4 7.9 3.2 5.3 2.3 9.9 7.2 9.0 9.7 8.3 8.0 7.5 8.5 9.7 9.5 2.4 12.5 6.5 7.6 7.6 6.0 33.3 36.6 75.7 43.8 29.3 15.4 30.2 25.6 26.6 36.6 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446411-20455105 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favourable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavourable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 11.2 14.2 13.2 13.1 14.5 10.7 14.4 21.3 18.3 14.3 15.6 18.6 11.6 8.8 16.0 19.2 12.9 13.1 13.6 15.8 13.4 10.2 12.3 22.2 12.4 16.9 13.4 12.5 12.4 12.4 10.6 20.8 13.6 15.5 10.8 14.0 14.5 12.4 18.6 19.6 9.9 12.4 16.8 12.3 18.8 13.6 5.7 15.2 16.2 15.7 9.6 18.7 16.6 11.0 24.5 28.8 23.4 19.1 13.0 14.2 15.7 6.3 10.3 3.4 10.0 5.9 4.1 10.5 5.0 6.6 12.8 12.4 14.2 7.5 13.3 6.5 6.3 5.6 10.3 10.1 8.0 10.5 13.2 8.4 8.7 18.2 4.4 14.4 12.0 3.1 3.1 15.3 8.1 8.4 8.1 7.6 10.0 11.9 14.1 6.3 5.1 20.4 22.5 6.4 7.5 7.2 7.3 13.3 2.6 8.9 9.4 6.8 6.3 13.7 3.9 5.4 13.2 6.8 6.0 2.3 12.5 18.2 3.3 22.5 6.5 5.1 19.1 23.4 13.7 17.6 11.9 20.5 14.2 12.0 28.8 24.5 11.3 12.9 8.7 13.0 13.6 12.4 12.9 15.7 13.2 14.5 21.3 18.3 13.4 10.2 13.4 12.5 15.5 15.2 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favourable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 6.6 17.0 8.6 6.5 12.1 2.6 11.1 12.9 10.9 7.3 5.6 14.8 2.9 5.0 11.8 9.1 7.0 8.1 4.8 13.0 8.4 7.3 13.0 11.6 5.8 11.2 18.9 9.3 13.8 6.1 7.5 9.8 6.1 11.6 6.9 6.1 9.0 9.7 6.1 16.6 9.2 6.5 8.1 13.4 9.6 5.8 9.4 15.4 10.6 8.2 7.3 9.2 8.0 5.8 9.3 6.0 2.1 2.6 6.6 11.5 3.0 5.7 3.2 14.1 10.8 11.2 6.2 8.4 8.9 6.3 12.7 13.7 3.7 6.0 3.8 10.0 3.7 8.4 12.5 10.6 14.5 9.8 9.6 12.4 7.8 4.8 5.9 7.0 6.5 6.8 9.0 9.6 4.7 9.4 4.5 6.1 8.3 3.2 5.5 8.0 6.8 14.6 6.0 11.3 6.5 8.2 3.2 8.6 9.5 6.0 10.9 19.4 8.5 7.7 3.9 8.3 7.3 12.1 5.5 6.2 5.2 6.2 11.0 9.0 9.0 0.2 2.6 2.1 7.3 2.4 10.5 7.4 7.7 8.4 3.5 9.3 11.5 10.2 0.4 6.6 2.1 6.0 5.9 3.0 8.6 12.1 12.9 10.9 8.4 7.3 18.9 9.3 11.6 15.4 OTC ENSG00000036473 "Ornithine carbamoyltransferase" P00480 X 38352545-38421450 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "intestine: 59.1;liver: 90.3" "Cell line enhanced" "Detected in some" "NB-4: 1.8;RPMI-8226: 1.0;SH-SY5Y: 1.1;SiHa: 1.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 59.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000243, HPA000570" Enhanced Supported Mitochondria 1800000 Mitochondria "HPA000243: AB_1079535, HPA000570: AB_1079534" "unprognostic (6.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.89e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.70e-3)" "unprognostic (5.61e-2)" 0.4 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.1 0.8 16.5 0.0 0.2 26.9 1.1 0.2 0.2 0.3 5.3 0.2 0.1 0.2 0.1 90.3 0.7 2.3 0.2 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.1 0.1 59.1 0.8 0.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.6 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.0 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 108.8" "Cell line enhanced" "Detected in many" "HeLa: 56.1;SiHa: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" 1000000 Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favourable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 21.9 8.0 17.3 7.5 30.3 5.8 9.5 26.6 36.8 6.7 9.2 8.3 10.7 4.4 8.6 8.7 13.1 6.9 7.5 108.8 19.3 15.2 25.3 1.2 4.2 9.5 13.1 25.7 7.2 3.0 20.9 8.4 2.8 21.2 12.5 10.4 6.6 8.5 14.7 13.4 10.7 6.5 17.0 8.9 5.2 14.6 6.2 5.3 22.8 13.0 10.7 11.8 8.0 7.5 8.0 4.6 3.3 1.6 7.5 15.6 5.1 7.8 0.3 6.5 7.7 20.1 10.8 0.0 14.1 8.9 11.7 7.1 1.2 5.4 20.4 3.5 10.7 4.6 17.8 12.7 13.8 17.4 2.0 14.3 56.1 2.6 8.8 27.7 4.8 10.1 3.4 11.5 19.4 10.7 2.9 26.3 13.4 1.0 23.1 1.3 1.4 5.6 18.4 18.2 15.4 9.5 0.6 6.5 6.7 72.9 0.0 8.6 0.1 6.0 6.4 9.3 12.2 15.9 11.3 4.3 3.6 0.8 14.1 20.4 7.1 1.0 1.0 3.3 9.1 1.1 10.9 8.0 9.2 9.8 4.6 6.1 10.8 8.9 0.3 7.5 1.6 1.8 15.6 5.1 17.3 30.3 26.6 36.8 19.3 15.2 13.1 25.7 21.2 5.3 OXCT2 "FKSG25, FLJ00030, SCOT-T" ENSG00000198754 "3-oxoacid CoA-transferase 2" Q9BYC2 1 39769523-39771348 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 31.8" "Cell line enhanced" "Detected in many" "Karpas-707: 9.8;THP-1: 10.5;U-266/70: 8.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 3.3;naive B-cell: 1.9;NK-cell: 1.4" "Group enriched" "Detected in many" 9 "B-cells: 3.3;NK-cells: 1.4" HPA075423 Enhanced "HPA075423: " "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (6.50e-2)" "unprognostic (7.16e-2)" "unprognostic (9.68e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (1.93e-3)" "unprognostic (2.74e-1)" "unprognostic (3.16e-1)" "unprognostic (2.57e-3)" "unprognostic (4.18e-2)" "unprognostic (5.39e-5)" "unprognostic (3.24e-1)" "unprognostic (4.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.85e-1)" 0.0 0.6 0.2 0.2 0.2 0.1 0.0 0.8 0.5 0.3 0.3 0.4 0.5 0.7 0.4 0.2 0.5 3.9 0.4 0.1 0.0 0.1 0.0 0.3 0.3 1.5 0.4 0.2 0.3 0.0 0.8 0.2 0.0 1.2 0.0 1.4 0.5 0.4 0.4 0.3 0.2 31.8 1.6 0.0 0.1 0.0 3.3 0.0 0.0 0.2 1.4 0.0 0.1 0.5 0.3 0.0 1.2 0.4 1.4 0.0 1.4 0.0 1.4 0.7 4.9 0.6 0.0 1.0 2.0 0.5 1.5 0.1 0.7 0.0 3.2 0.9 3.2 0.2 2.4 0.0 0.5 0.7 0.4 0.2 0.1 1.0 0.3 9.8 0.2 1.4 0.0 1.5 0.1 1.3 1.3 1.5 1.5 0.3 1.0 1.6 0.8 4.3 0.3 1.4 0.5 10.5 1.1 0.0 0.3 4.7 0.0 8.1 4.3 0.6 0.1 0.6 2.3 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 OXSM "CEM1, FASN2D, FLJ20604, KS" ENSG00000151093 "3-oxoacyl-ACP synthase, mitochondrial" Q9NWU1 3 25782917-25794534 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021293, HPA021300, HPA021337" Enhanced Approved Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA021293: AB_1848772, HPA021300: AB_1848774, HPA021337: AB_1848776" "unprognostic (2.20e-2)" "unprognostic (3.28e-1)" "prognostic favourable (1.35e-4)" "prognostic favourable (5.51e-4)" "unprognostic (1.01e-1)" "unprognostic (8.17e-2)" "unprognostic (2.15e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "unprognostic (2.83e-2)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "prognostic favourable (4.18e-9)" "unprognostic (1.79e-2)" "unprognostic (2.42e-1)" "unprognostic (3.10e-1)" "unprognostic (1.73e-2)" 6.2 13.7 6.7 9.8 10.5 3.7 10.3 8.3 11.9 6.0 11.8 6.2 13.7 10.1 6.4 16.2 10.3 7.7 7.9 13.5 6.6 6.4 14.9 26.1 10.0 7.7 6.6 6.5 6.4 18.7 8.3 13.0 7.3 7.0 8.0 13.8 10.4 15.5 15.6 19.4 8.3 8.9 5.8 6.7 9.6 8.9 19.9 8.0 8.1 11.7 12.3 11.3 7.9 6.4 8.4 9.0 3.7 6.5 10.3 11.8 6.6 7.6 12.9 2.7 7.6 8.0 8.8 7.9 6.2 9.0 11.6 8.3 9.8 9.2 14.3 8.4 5.6 8.1 11.3 11.8 11.0 8.5 11.5 15.7 10.9 11.8 9.8 12.7 10.0 8.2 14.8 9.3 9.7 10.0 16.1 11.6 9.8 11.5 9.2 9.8 0.5 14.8 12.4 7.2 23.3 17.1 4.8 3.9 7.2 9.8 16.9 12.6 18.5 11.8 6.1 7.3 8.7 9.5 8.9 11.1 12.7 4.5 10.3 11.2 7.4 2.1 5.4 3.7 9.4 6.0 10.8 8.4 9.7 11.6 8.6 8.2 11.4 11.8 0.9 10.3 6.5 9.0 6.0 6.6 6.7 10.5 8.3 11.9 6.6 6.4 6.6 6.5 7.0 8.0 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive 1" O95747 3 38165089-38255488 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol 21000000 Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 17.6 16.8 9.4 18.3 13.4 24.2 15.9 17.4 14.9 16.8 15.4 9.2 35.7 12.4 14.9 14.7 31.6 11.6 18.9 15.5 11.9 9.0 18.3 17.6 14.6 13.9 13.6 9.3 16.7 12.3 23.7 15.3 21.4 12.3 16.5 16.8 13.0 15.1 23.9 32.6 17.4 21.4 17.0 12.9 15.8 14.0 11.2 13.2 26.2 14.2 24.1 19.6 23.5 19.2 2.3 4.4 10.1 4.8 5.0 4.7 1.6 17.5 8.0 16.1 11.2 11.2 13.0 18.3 15.6 21.4 22.5 24.5 10.3 11.5 19.5 7.9 18.6 10.9 21.6 16.0 29.8 20.6 8.8 21.3 17.1 11.3 13.5 13.1 13.0 10.3 18.9 20.8 33.7 14.0 16.1 11.2 38.5 4.9 25.3 9.5 16.9 9.6 8.8 13.5 15.0 13.9 13.4 8.4 12.9 17.0 43.2 10.6 14.2 8.6 12.7 14.2 14.1 21.5 23.0 8.6 10.2 14.3 19.4 16.4 28.2 10.1 2.8 6.1 3.3 4.8 3.5 1.9 4.0 3.1 4.4 2.3 3.0 3.7 5.5 5.0 4.1 2.5 4.7 1.6 9.4 13.4 17.4 14.9 11.9 9.0 13.6 9.3 12.3 13.2 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell line enhanced" "Detected in many" "U-266/70: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.8 8.0 17.4 7.8 7.1 11.9 13.9 13.6 9.7 12.9 15.2 11.4 15.9 10.6 5.0 11.7 6.1 12.1 14.4 20.4 12.2 9.8 11.2 5.4 0.7 4.7 18.9 16.6 8.8 8.7 15.1 22.5 3.0 7.4 18.7 23.4 0.8 12.0 8.7 25.7 6.9 18.5 22.5 0.4 3.3 9.9 7.5 7.4 7.3 3.1 5.7 13.9 8.6 0.2 8.6 14.9 45.9 11.3 51.4 26.4 7.0 7.2 12.6 9.3 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles 590000 "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.36e-4)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 28.7 18.9 22.4 27.6 23.5 21.4 56.5 17.4 20.7 19.5 23.0 27.8 17.4 19.0 22.6 19.2 23.4 17.9 20.7 29.0 22.6 22.0 19.5 34.3 35.7 50.2 26.8 13.5 19.9 16.6 30.5 13.0 27.6 22.8 17.7 23.0 12.9 19.6 21.2 34.2 16.3 25.2 23.0 32.1 34.6 18.4 15.9 24.8 44.9 16.9 19.1 31.9 24.1 32.7 6.6 13.7 25.9 12.6 6.6 10.8 7.0 35.2 12.6 17.8 13.0 12.6 16.7 26.4 17.9 14.8 19.5 17.8 29.9 18.1 22.6 51.2 18.1 18.1 18.8 17.0 30.2 10.1 9.1 33.5 14.5 23.5 25.6 32.5 32.2 13.3 14.0 17.4 37.1 19.2 16.1 28.2 18.9 37.2 30.9 16.8 10.6 19.0 28.3 10.1 20.5 17.0 24.8 10.4 11.8 23.9 16.9 13.5 59.3 23.6 19.8 16.2 9.0 16.9 26.3 19.2 33.9 55.7 13.4 32.6 15.3 16.5 10.3 24.5 6.3 12.6 8.5 6.4 7.3 7.1 13.7 6.6 5.4 6.3 25.9 6.6 10.8 5.1 10.8 7.0 22.4 23.5 17.4 20.7 22.6 22.0 26.8 13.5 22.8 24.8 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;pancreas: 46.5;pituitary gland: 37.2" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HAP1: 8.7;HDLM-2: 10.9;NTERA-2: 8.5;SCLC-21H: 11.1;SH-SY5Y: 6.9;U-2197: 6.7;U-251 MG: 11.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Cytosol Cytosol "HPA044791: , HPA060219: " "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 2.0 6.8 17.6 2.5 17.5 1.0 6.4 1.8 24.6 3.7 1.6 0.9 9.1 1.0 6.8 7.6 1.7 3.7 2.6 1.2 26.2 20.8 1.6 1.1 1.8 2.5 7.9 21.9 7.9 46.5 0.9 37.2 1.6 12.9 4.8 1.7 1.4 3.0 7.1 2.4 2.0 1.4 6.1 5.8 2.9 3.0 3.6 1.9 0.0 7.7 0.0 1.7 2.0 1.5 0.1 0.1 0.6 0.1 0.2 4.3 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 9.7 1.0 0.0 8.7 0.5 1.2 10.9 0.3 0.0 1.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 2.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 8.5 1.9 0.1 4.0 0.0 0.8 0.0 11.1 6.9 0.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 6.7 11.6 0.0 0.1 0.1 1.2 0.0 0.1 0.6 0.1 0.1 0.1 0.0 4.3 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.3 0.0 17.6 17.5 1.8 18.5 26.2 20.8 7.9 21.9 12.9 1.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 44.6;MCF7: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavourable (9.85e-4)" "prognostic favourable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 6.8 11.1 11.0 12.7 12.3 4.8 11.9 13.7 12.4 17.3 19.6 13.7 19.9 26.0 12.2 17.3 20.1 15.3 16.5 8.1 10.9 8.1 19.4 17.0 18.7 5.4 13.7 7.7 13.8 29.6 11.2 17.0 23.0 10.3 29.6 8.1 19.7 40.9 18.5 10.3 18.6 25.1 9.0 8.3 7.9 18.6 22.3 12.5 8.8 15.2 10.1 14.7 11.5 15.0 2.8 3.4 4.2 2.5 3.6 4.5 1.9 17.6 44.6 6.6 10.1 2.1 2.2 20.1 8.4 3.4 5.7 5.7 29.2 15.0 4.0 12.8 5.3 6.5 3.6 6.7 2.1 10.7 10.2 4.8 8.1 14.2 3.4 4.8 7.0 2.7 3.0 5.3 3.8 7.4 9.5 3.2 3.4 49.1 5.1 5.3 12.1 10.7 5.2 5.2 3.0 5.5 19.4 21.3 14.7 8.6 38.3 9.5 17.0 8.0 12.3 9.7 16.7 11.1 15.0 3.6 3.4 3.3 11.9 2.9 11.6 1.0 2.5 4.2 2.6 1.4 3.6 2.2 2.9 4.5 3.4 2.8 2.2 2.2 2.1 3.6 2.1 2.9 3.0 1.9 11.0 12.3 13.7 12.4 10.9 8.1 13.7 7.7 10.3 12.5 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537389-9839041 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.3" "Group enriched" "Detected in some" 9 "SCLC-21H: 10.0;SH-SY5Y: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.5 5.2 5.7 0.6 11.7 0.5 1.6 30.3 19.6 0.8 0.6 0.8 0.0 0.7 1.0 2.2 1.0 0.7 3.4 0.6 4.0 3.3 1.0 2.3 0.7 0.6 1.6 8.8 0.6 3.5 0.5 2.0 0.6 5.3 1.6 0.6 0.6 1.2 1.6 0.6 1.6 0.6 0.6 1.2 0.6 1.2 1.0 1.7 0.0 0.6 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 10.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 5.7 11.7 30.3 13.6 4.0 3.3 1.6 8.8 5.3 1.7 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40238759-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 22.2" "Cell line enhanced" "Detected in many" "CACO-2: 14.5;HaCaT: 22.5;hTCEpi: 13.8;SK-BR-3: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.3 5.3 14.7 0.8 18.4 0.8 2.3 11.3 20.1 3.0 1.3 1.6 2.5 1.4 1.0 1.1 15.8 4.3 1.4 7.9 11.6 5.2 3.4 0.4 2.6 1.0 3.0 10.9 0.6 7.4 12.9 6.4 8.1 2.1 3.6 1.2 0.3 3.4 7.5 3.5 22.2 1.4 0.8 1.2 1.0 3.6 12.8 2.2 0.0 7.4 8.5 5.1 3.0 5.1 1.4 0.7 2.9 0.7 2.0 5.5 1.2 2.6 0.0 0.2 0.1 0.0 0.0 4.3 0.0 0.1 0.6 0.4 14.5 2.0 0.1 2.3 0.0 22.5 3.2 4.8 0.2 0.1 0.7 0.0 1.9 0.1 0.0 0.1 0.3 0.0 13.8 0.2 3.2 0.0 1.1 0.2 0.0 3.1 0.0 0.3 0.4 2.0 0.2 0.1 1.8 1.1 5.9 5.2 1.3 1.8 7.6 0.2 0.8 7.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.5 0.3 0.1 2.1 0.7 2.9 5.5 0.3 2.1 1.4 0.5 4.2 0.7 0.5 0.3 1.2 1.3 2.0 0.2 0.5 0.1 1.2 14.7 18.4 11.3 20.1 11.6 5.2 3.0 10.9 2.1 2.2 PANK1 "MGC24596, PANK, PANK1a, PANK1b" ENSG00000152782 "Pantothenate kinase 1" Q8TE04 10 89579497-89645572 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 20.1;liver: 63.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (6.71e-2)" "unprognostic (6.97e-2)" "prognostic favourable (1.50e-4)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.55e-4)" "unprognostic (4.61e-2)" "prognostic favourable (1.55e-10)" "unprognostic (3.49e-2)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" "unprognostic (6.64e-2)" 1.1 2.5 2.3 1.2 1.9 0.0 1.0 13.4 4.1 2.4 6.1 1.3 0.5 9.0 0.9 1.9 2.9 1.2 1.5 3.9 1.9 2.6 20.1 63.8 2.1 0.6 2.1 2.7 1.1 1.2 2.6 2.2 1.0 3.1 1.5 7.8 1.8 1.4 1.0 5.7 5.5 9.2 1.0 1.7 0.9 2.0 1.5 1.0 2.6 4.7 2.4 1.0 1.1 5.5 1.0 2.3 0.9 0.6 0.1 1.6 0.7 5.6 3.7 20.8 14.2 11.3 8.2 10.5 3.3 3.6 3.2 4.3 5.8 5.9 4.1 2.2 2.5 5.7 9.4 2.1 3.5 1.4 4.2 2.7 4.1 11.5 3.3 8.6 1.6 5.0 9.4 4.8 3.8 3.7 4.7 0.5 4.6 4.4 9.5 8.8 16.3 2.3 8.4 4.1 2.7 9.9 2.7 6.5 7.8 4.2 5.1 3.3 5.5 6.3 1.6 1.9 1.8 3.8 4.0 4.8 8.8 5.1 2.6 6.9 1.3 0.9 0.3 0.1 0.7 0.1 1.4 1.0 0.8 1.6 1.0 0.1 1.0 0.2 0.7 0.1 0.6 2.3 1.1 0.7 2.3 1.9 13.4 4.1 1.9 2.6 2.1 2.7 3.1 1.0 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929882 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavourable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 15.2 21.5 18.7 18.5 18.9 20.8 19.7 21.8 24.8 14.7 14.4 16.8 10.7 11.8 15.5 15.5 28.9 19.1 14.3 11.0 17.4 18.6 18.8 20.3 16.1 18.5 16.2 16.2 14.4 13.5 15.3 15.7 18.1 20.8 14.5 16.4 17.0 15.8 13.2 14.4 12.8 14.5 16.6 12.3 20.6 12.1 28.9 14.1 23.2 17.0 10.5 24.6 17.3 16.4 5.8 8.6 8.0 12.8 8.3 6.4 3.1 21.4 13.9 15.0 7.6 18.0 15.6 8.2 14.1 15.5 18.6 24.1 18.7 11.5 17.4 6.5 15.8 17.7 16.1 27.4 23.8 5.1 7.1 23.8 9.9 34.9 15.1 15.8 7.9 13.7 12.0 20.7 13.4 17.4 17.5 16.3 20.0 5.3 13.6 14.0 15.0 10.4 11.2 20.9 11.0 11.5 19.7 19.6 9.6 17.5 19.2 34.9 11.6 12.8 11.9 22.3 11.2 29.1 21.6 9.2 26.6 13.3 6.6 14.5 17.4 1.6 11.2 4.7 4.4 12.8 4.3 4.7 4.3 4.5 8.6 5.8 4.4 4.0 8.0 8.3 10.7 3.0 6.4 3.1 18.7 18.9 21.8 24.8 17.4 18.6 16.2 16.2 20.8 14.1 PANK3 FLJ12899 ENSG00000120137 "Pantothenate kinase 3" Q9H999 5 168548495-168579600 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 63.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062358 Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA062358: " "unprognostic (1.24e-2)" "unprognostic (5.71e-2)" "prognostic favourable (3.94e-4)" "unprognostic (7.65e-3)" "unprognostic (2.47e-2)" "unprognostic (2.42e-2)" "unprognostic (1.20e-2)" "unprognostic (8.43e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (9.48e-2)" "unprognostic (2.30e-1)" "unprognostic (3.71e-2)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (1.97e-3)" "unprognostic (2.01e-1)" 9.1 16.6 11.6 17.5 10.4 10.5 17.6 22.8 11.9 8.9 23.9 9.0 8.5 28.0 10.2 8.8 12.8 7.8 6.9 7.4 11.7 9.1 13.2 39.2 12.5 8.2 8.4 7.5 10.7 8.8 14.6 11.2 9.4 10.8 9.1 17.9 6.7 11.0 9.6 8.2 11.9 63.0 8.0 10.3 9.6 10.9 10.2 11.0 10.2 10.5 13.4 8.2 9.9 11.6 4.1 2.7 3.5 4.7 0.9 2.5 1.1 13.8 7.8 32.3 17.2 12.1 14.1 13.7 8.3 8.9 11.2 16.5 12.9 12.9 21.3 13.7 11.7 10.0 21.6 16.7 20.1 19.8 10.5 10.9 7.4 9.5 14.1 14.7 14.8 11.2 22.6 14.0 15.8 13.1 10.0 21.6 15.2 7.7 14.6 6.7 13.8 5.7 10.7 22.1 8.7 14.0 20.5 15.1 32.3 9.6 15.8 23.6 20.6 18.6 13.4 15.1 21.2 8.9 17.7 15.1 20.7 15.9 8.9 15.0 11.7 3.5 3.2 1.6 1.9 3.8 2.5 4.1 1.9 1.9 2.0 1.6 1.3 2.3 1.3 0.9 4.7 2.7 2.4 1.1 11.6 10.4 22.8 11.8 11.7 9.1 8.4 7.5 10.8 11.0 PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4" Q9NVE7 1 2508533-2526628 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 43.1" "Cell line enhanced" "Detected in many" "BJ: 8.9;HDLM-2: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol Cytosol "HPA011723: , HPA012036: AB_1854952, HPA027961: AB_10602042" "unprognostic (1.23e-1)" "unprognostic (2.31e-1)" "unprognostic (3.36e-1)" "unprognostic (1.13e-1)" "unprognostic (4.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-1)" "unprognostic (6.51e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (3.29e-2)" "prognostic favourable (1.57e-5)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.15e-2)" 5.3 14.4 10.7 17.8 12.6 4.2 5.4 14.9 12.4 5.5 7.1 6.8 4.9 4.2 7.0 4.2 9.8 5.6 9.2 11.8 8.0 5.2 7.2 7.0 6.7 12.5 9.0 6.8 5.7 5.8 4.2 8.3 6.7 7.4 5.8 6.1 8.9 5.6 5.3 43.1 19.0 7.6 9.1 4.4 8.1 6.3 11.0 9.7 9.4 6.8 6.8 7.2 7.2 5.7 4.5 4.8 11.7 6.9 11.4 8.9 5.3 2.4 6.6 2.3 0.0 0.0 2.7 1.5 8.9 0.0 8.0 7.6 0.0 0.0 1.1 3.0 2.4 3.8 1.9 0.0 1.7 9.2 5.6 0.0 3.8 5.5 2.5 0.0 4.6 0.0 0.0 0.0 0.0 1.9 2.5 0.0 2.1 0.0 1.3 0.2 0.0 2.8 0.0 0.0 1.8 0.0 0.0 2.0 0.0 5.0 1.8 0.0 0.0 3.3 0.0 0.0 1.9 4.6 2.1 1.3 4.5 5.9 3.0 0.9 0.0 11.7 4.9 4.5 6.2 6.6 5.1 4.5 3.9 6.4 4.8 3.0 7.4 8.0 6.4 11.4 6.9 0.9 8.9 5.3 10.7 12.6 14.9 12.4 8.0 5.2 9.0 6.8 7.4 9.7 PAPD4 "FLJ38499, GLD2, TUT2" ENSG00000164329 "Poly(A) RNA polymerase D4, non-canonical" Q6PIY7 5 79612120-79686648 "Enzymes, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol Cytosol "HPA054468: " "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (8.03e-2)" "unprognostic (2.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.10e-1)" "unprognostic (6.80e-2)" "unprognostic (1.57e-3)" "unprognostic (9.37e-2)" "unprognostic (2.21e-1)" "unprognostic (7.71e-2)" "unprognostic (2.38e-1)" "unprognostic (8.43e-3)" "unprognostic (5.84e-3)" "unprognostic (2.67e-3)" 25.4 21.1 15.8 34.4 22.1 42.1 27.9 20.9 30.3 23.8 22.6 24.7 22.7 19.2 34.4 28.1 22.0 20.7 23.3 16.5 16.5 14.6 20.0 25.3 25.6 34.7 19.4 20.2 29.6 21.4 18.0 23.1 25.7 17.2 20.6 23.3 23.8 21.4 28.3 21.0 25.5 25.4 23.1 22.2 37.4 21.0 26.0 21.2 33.8 24.9 21.3 29.3 22.6 21.9 20.2 19.5 22.3 22.1 19.3 29.9 15.7 11.4 8.0 8.9 14.1 15.7 18.3 14.3 13.9 21.4 16.3 26.1 7.1 13.7 21.5 7.3 15.3 11.0 11.4 15.4 18.7 15.9 10.5 12.2 9.9 11.0 20.4 18.0 16.9 16.1 16.8 11.5 21.6 13.7 13.9 15.9 17.9 6.2 20.5 23.2 8.3 5.7 18.4 9.0 23.9 15.8 16.5 5.9 10.8 11.0 12.1 21.8 10.4 28.6 12.6 8.8 6.0 8.5 15.3 16.7 13.9 21.3 15.6 19.0 12.3 22.3 19.1 18.6 18.2 22.1 29.9 20.2 19.9 19.9 19.5 16.2 19.3 19.8 17.3 19.3 21.7 10.7 20.2 15.7 15.8 22.1 20.9 30.3 16.5 14.6 19.4 20.2 17.2 21.2 PAPD5 TRF4-2 ENSG00000121274 "Poly(A) RNA polymerase D5, non-canonical" Q8NDF8 16 50152918-50235310 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, rRNA processing" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042968, HPA048225" Uncertain "HPA042968: , HPA048225: " "unprognostic (1.05e-2)" "unprognostic (4.09e-2)" "unprognostic (1.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.27e-1)" "unprognostic (2.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (3.30e-2)" "prognostic favourable (1.85e-4)" "unprognostic (4.24e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (7.00e-2)" 9.4 9.9 5.9 8.8 8.6 19.2 12.6 14.9 10.8 15.9 10.0 4.5 8.8 11.1 13.1 6.3 7.4 10.8 6.3 8.0 7.7 6.9 10.0 11.9 8.5 11.2 6.4 8.0 10.5 7.9 18.5 13.4 9.2 7.5 10.0 6.4 6.7 7.6 9.8 9.9 8.1 9.4 9.7 6.1 6.0 8.0 12.3 8.0 6.8 7.5 6.0 6.6 13.1 30.8 3.5 4.9 4.6 2.9 7.2 5.6 1.2 11.3 8.7 7.1 12.7 11.2 9.5 9.1 10.2 10.4 12.3 5.7 12.0 8.1 13.7 12.2 12.4 8.6 13.3 7.6 16.2 8.0 8.7 8.2 4.7 15.5 12.6 6.8 12.7 5.7 9.4 10.1 12.8 8.5 8.4 4.8 11.3 4.9 9.5 10.2 9.2 9.4 12.8 14.2 17.9 3.5 4.2 9.1 5.4 10.3 13.3 7.0 4.4 5.0 7.3 11.4 10.0 9.9 5.8 9.6 7.4 18.1 6.8 6.3 8.1 4.6 2.6 1.3 4.0 2.9 3.5 2.9 4.3 4.8 2.0 3.5 4.8 5.6 4.0 7.2 2.1 4.9 3.7 1.2 5.9 8.6 14.9 10.8 7.7 6.9 6.4 8.0 7.5 8.0 PAPD7 "LAK-1, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Poly(A) RNA polymerase D7, non-canonical" Q5XG87 5 6713007-6757048 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavourable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favourable (8.55e-4)" 13.5 7.9 9.6 13.9 11.1 25.8 16.3 22.7 12.3 15.1 16.6 10.6 14.8 9.5 13.2 8.0 12.2 11.3 11.4 8.6 10.7 7.3 9.7 19.9 13.2 14.1 14.8 5.8 18.5 13.3 13.2 12.2 10.0 9.0 11.6 8.3 10.2 17.0 10.6 10.4 16.7 13.1 13.9 7.9 14.8 10.1 11.1 11.7 25.4 11.3 11.3 11.6 12.5 34.9 1.9 3.8 0.7 0.7 0.5 2.3 0.8 16.3 11.1 13.7 16.8 9.9 8.9 19.7 11.1 14.0 13.9 15.8 11.5 9.1 12.0 8.6 13.7 12.2 11.1 8.6 12.8 13.4 7.1 6.1 35.1 6.2 6.2 9.2 9.3 6.0 7.5 15.5 10.0 8.1 8.2 15.9 11.3 9.0 12.5 12.0 7.4 8.7 11.3 11.6 3.0 5.5 9.4 13.6 10.4 26.6 12.9 7.6 7.8 5.1 7.1 16.7 17.5 14.6 15.5 15.2 6.3 10.6 10.8 8.6 10.3 0.0 0.7 0.7 2.1 0.4 2.3 1.9 1.7 1.6 1.2 1.5 1.9 1.7 0.4 0.5 0.6 3.8 1.8 0.8 9.6 11.1 22.7 12.3 10.7 7.3 14.8 5.8 9.0 11.7 PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567111 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm Nucleoplasm "HPA001788: AB_1079564" "unprognostic (3.18e-1)" "unprognostic (1.30e-1)" "unprognostic (9.69e-2)" "unprognostic (7.26e-2)" "unprognostic (9.10e-2)" "unprognostic (5.10e-3)" "prognostic unfavourable (2.41e-5)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.22e-3)" "unprognostic (3.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (4.05e-1)" 35.8 43.4 49.1 45.7 51.6 54.5 39.7 61.2 60.5 41.0 45.1 25.2 45.6 34.9 43.8 48.3 42.0 38.7 35.6 71.8 46.3 39.6 40.0 50.2 37.1 44.7 48.1 39.7 58.2 52.9 50.2 68.7 54.5 45.6 45.1 45.8 24.0 39.2 45.5 46.4 35.5 45.5 38.9 41.9 50.9 40.4 53.0 55.7 53.0 54.8 34.8 49.6 44.9 119.5 26.4 23.0 39.0 23.5 25.2 23.4 19.8 32.0 31.0 39.9 40.0 28.9 32.7 90.8 29.4 31.8 35.0 33.7 35.8 33.2 43.5 33.9 34.4 27.8 13.0 40.5 62.8 35.9 21.1 35.1 23.5 35.1 29.9 45.9 35.6 29.8 35.5 39.1 35.0 39.1 32.9 39.9 33.7 46.7 35.9 23.3 27.2 35.3 38.4 48.6 25.2 34.9 51.2 41.0 27.2 39.2 30.8 28.6 43.7 40.4 31.1 24.7 19.7 27.8 35.8 31.5 47.1 38.4 40.0 35.2 41.4 39.0 19.7 32.7 15.5 23.5 20.4 23.8 19.6 22.6 23.0 26.4 23.4 21.8 27.4 25.2 22.6 15.2 18.7 19.8 49.1 51.6 61.2 60.5 46.3 39.6 48.1 39.7 45.6 55.7 PAPOLB PAPT ENSG00000218823 "Poly(A) polymerase beta" Q9NRJ5 7 4857733-4861994 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 33.0" "Cell line enhanced" "Detected in single" "THP-1: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (7.58e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.5 0.1 PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756230-60802085 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced Nucleoplasm Nucleoplasm "CAB017795: , HPA035349: , HPA035350: " "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavourable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" 12.3 9.5 11.6 11.6 11.9 5.8 9.9 19.4 15.3 10.2 8.2 9.8 7.8 6.8 12.1 6.2 10.1 9.0 10.2 8.5 15.1 10.1 8.6 6.9 9.4 14.8 10.9 11.3 17.1 9.9 13.3 18.9 11.8 12.5 9.6 9.2 7.7 11.1 8.7 13.1 11.7 9.7 9.9 21.0 15.0 9.1 14.2 11.0 23.1 27.5 6.6 14.3 10.9 11.1 6.1 3.7 13.2 6.9 9.4 9.7 4.1 5.1 4.8 9.0 7.3 11.6 8.7 8.6 5.7 5.6 4.9 5.2 8.1 4.4 7.4 6.0 4.4 8.7 12.7 5.4 9.2 12.8 6.8 9.4 4.7 5.7 7.0 9.8 6.5 6.5 6.4 5.9 12.4 7.8 9.2 7.0 5.4 4.1 11.3 6.7 14.3 4.4 9.3 16.0 6.6 5.3 4.9 5.3 7.4 9.1 5.7 5.1 3.8 6.0 7.3 6.3 7.6 4.7 5.3 7.0 4.1 18.0 5.1 11.2 4.5 13.2 4.1 8.7 6.7 4.3 8.3 5.9 7.2 6.0 3.7 6.1 7.9 7.3 10.6 9.4 6.9 3.3 9.7 4.1 11.6 11.9 19.4 15.3 15.1 10.1 10.9 11.3 12.5 11.0 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720452 "Enzymes, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 50.3;eosinophil: 62.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA049781: " "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favourable (9.14e-4)" "prognostic favourable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 13.5 7.4 24.3 14.4 28.5 11.1 25.2 16.4 32.2 26.6 10.0 45.0 9.4 7.9 25.1 22.8 18.3 24.9 13.3 7.7 31.3 23.9 16.7 5.1 22.0 14.7 29.7 21.9 15.6 24.6 15.6 15.5 8.5 38.2 21.7 12.7 9.5 32.2 14.0 3.3 24.5 8.5 17.0 59.9 9.6 30.4 8.1 25.5 14.7 10.3 11.0 24.6 16.5 13.7 8.5 9.2 62.2 10.2 4.6 6.8 5.8 10.5 9.6 16.3 20.4 20.2 25.5 13.1 13.4 25.4 13.2 17.7 14.7 15.3 16.5 8.6 24.7 13.3 15.4 26.6 17.0 38.7 11.7 19.2 20.9 32.9 11.1 29.1 33.3 21.1 13.8 15.2 12.5 29.2 4.2 32.1 36.9 16.1 23.4 9.0 17.5 10.7 19.7 25.9 4.7 19.8 14.7 18.6 26.9 13.9 21.1 16.4 12.5 4.5 17.2 16.5 17.0 11.0 11.3 25.8 17.1 15.4 20.1 22.3 25.9 50.3 8.9 62.2 3.0 9.6 3.5 8.5 4.0 3.4 9.2 4.1 2.5 2.9 9.4 4.6 10.2 1.8 6.8 5.8 24.3 28.5 16.4 32.2 31.3 23.9 29.7 21.9 38.2 25.5 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.2;liver: 49.0" "Cell line enhanced" "Detected in many" "BJ: 34.9;fHDF/TERT166: 88.3;HHSteC: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.3;myeloid DC: 2.7;non-classical monocyte: 9.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.7;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria Mitochondria "HPA071224: , HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favourable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavourable (3.21e-5)" "unprognostic (3.46e-3)" 16.0 59.2 3.5 18.1 6.0 0.3 18.1 1.9 4.3 8.6 25.5 2.2 1.9 9.2 4.0 7.0 3.7 5.3 10.7 9.1 3.9 2.1 9.9 49.0 31.3 15.6 4.4 1.6 10.8 21.2 0.4 1.7 19.0 5.2 3.8 21.2 6.2 6.2 2.0 4.8 1.7 19.4 5.5 3.4 2.9 2.9 3.6 4.3 0.8 7.3 6.2 11.0 5.7 5.3 0.0 2.7 0.8 9.7 0.0 0.1 0.8 3.5 3.6 1.1 0.0 25.3 32.3 0.0 34.9 29.9 21.2 15.4 0.1 0.7 0.0 1.8 88.3 1.5 2.6 2.4 24.3 0.0 1.9 1.6 2.6 0.0 38.3 0.0 0.7 11.4 0.0 12.2 1.0 17.7 0.0 16.5 14.9 13.3 0.0 0.1 1.3 4.5 0.0 0.0 0.0 22.1 1.5 0.1 0.3 17.0 0.6 0.2 2.5 0.9 22.0 7.2 4.2 24.4 2.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.4 0.0 0.0 5.3 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.8 0.0 9.7 0.0 0.0 0.8 3.5 6.0 1.9 4.3 3.9 2.1 4.4 1.6 5.2 4.3 PARP1 "ADPRT, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360691-226408079 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm 39000 Nucleoplasm "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: , CAB075727: , HPA045168: " "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavourable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavourable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 17.3 16.6 31.2 35.7 31.2 14.3 15.3 21.1 29.2 14.3 21.8 37.4 10.3 15.0 18.2 13.0 18.1 15.0 10.8 24.2 27.8 21.9 13.4 24.8 14.1 56.3 40.7 21.8 14.6 28.1 62.6 22.9 28.7 30.4 22.0 19.2 16.3 17.0 24.7 47.3 11.7 19.6 25.5 49.1 32.7 15.9 22.5 34.8 29.5 14.5 16.5 70.2 19.9 13.7 53.0 16.5 9.0 17.5 11.1 21.8 11.5 28.5 15.3 42.6 30.1 11.2 9.2 24.3 18.9 16.9 25.8 21.2 24.3 14.0 83.2 28.3 11.5 21.5 58.5 18.6 22.7 34.9 81.7 32.2 20.4 15.9 6.7 53.4 15.6 9.1 7.4 20.7 14.7 20.0 51.2 42.5 13.3 13.6 17.1 19.3 78.4 30.4 51.8 73.0 76.9 12.1 20.4 42.9 37.6 24.6 27.6 15.5 23.2 33.5 15.2 13.7 22.7 18.5 35.4 17.3 29.0 71.5 11.4 18.1 30.7 9.0 6.7 6.9 18.3 11.3 21.6 46.8 19.4 18.0 14.3 53.0 15.2 16.4 1.0 11.1 17.5 16.5 21.8 11.5 31.2 31.2 21.1 28.4 27.8 21.9 40.7 21.8 30.4 34.8 PARP10 FLJ14464 ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.4" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "HPA028122, HPA052427" Approved Supported "Nucleoli,Golgi apparatus,Cytosol" Nucleoli "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: " "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 14.2 18.8 8.8 27.4 9.5 15.7 18.6 5.3 8.7 14.4 16.5 9.3 20.7 20.5 20.3 18.3 15.8 18.0 21.8 6.4 8.9 4.1 20.5 19.1 21.4 23.6 10.4 6.8 22.4 15.3 9.3 14.2 10.4 9.2 17.7 3.8 12.7 27.7 14.9 12.5 14.3 21.8 9.6 8.9 31.1 13.1 15.8 9.8 27.8 15.4 10.4 21.6 8.8 12.9 2.4 16.4 3.2 2.8 1.9 4.6 2.4 8.4 0.8 0.6 1.5 4.2 3.8 4.6 1.4 1.8 9.5 10.7 0.4 14.8 10.5 20.2 4.5 3.2 0.2 5.0 0.4 23.7 0.0 11.6 4.9 5.3 4.1 4.5 14.0 2.4 5.0 4.7 1.9 1.4 0.2 8.4 1.8 10.3 15.7 7.9 0.5 6.8 14.8 1.7 14.1 3.9 10.7 0.5 0.5 9.8 1.0 18.6 11.0 6.8 6.5 4.9 7.4 8.2 5.2 14.3 8.4 2.4 7.1 15.4 2.6 0.0 1.9 3.2 4.6 2.8 3.0 1.2 2.2 3.7 2.3 2.4 1.6 2.3 1.1 1.9 2.7 16.4 1.6 2.4 8.8 9.5 5.3 8.7 8.9 4.1 10.4 6.8 9.2 9.8 PARP11 C12orf6 ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: AB_1854980" "unprognostic (9.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.87e-2)" 7.1 14.5 11.2 8.6 9.2 3.7 8.3 11.0 9.1 6.4 5.4 5.6 4.8 4.9 10.2 7.5 5.0 6.3 5.6 5.1 6.1 5.7 5.7 5.7 6.3 12.8 5.0 5.7 13.1 6.6 10.0 10.4 4.1 7.6 12.0 5.7 7.2 6.6 6.0 4.1 3.9 6.5 7.2 6.1 9.2 4.2 12.8 5.6 16.9 12.3 2.7 12.1 8.3 5.8 10.7 10.2 18.3 10.2 8.2 12.5 7.1 2.5 2.1 13.6 2.1 4.3 6.9 3.8 3.0 5.1 5.3 5.3 7.8 2.0 7.4 1.9 6.6 2.1 4.5 4.5 8.6 14.9 4.5 10.6 0.0 5.7 4.9 7.1 4.0 5.5 3.5 4.2 11.8 3.9 2.8 6.0 7.4 3.5 3.8 2.7 5.0 0.3 7.6 9.3 1.7 2.5 5.7 0.9 3.1 2.9 2.6 3.9 0.5 6.5 7.7 4.6 4.5 7.0 4.0 2.9 6.3 10.5 4.4 4.0 1.2 18.3 10.2 10.2 9.2 8.5 12.5 10.7 10.2 6.7 10.2 10.1 11.7 9.4 10.2 8.2 6.4 8.9 4.3 7.1 11.2 9.2 11.0 9.1 6.1 5.7 5.0 5.7 7.6 5.6 PARP12 "FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023744-140063721 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 11.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm Nucleoplasm "HPA003584: AB_1079568, HPA063872: " "unprognostic (1.46e-3)" "unprognostic (2.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "unprognostic (6.74e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (2.30e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (7.51e-3)" "unprognostic (2.68e-1)" "prognostic unfavourable (4.12e-7)" "unprognostic (3.31e-2)" "unprognostic (2.76e-1)" "unprognostic (1.75e-2)" "unprognostic (6.01e-2)" 3.1 1.8 1.0 3.7 0.9 6.1 2.5 0.1 0.7 2.1 2.2 4.2 2.8 4.2 2.1 2.5 3.1 1.7 1.0 1.0 3.1 3.0 5.2 3.8 1.0 3.2 2.7 2.5 3.3 3.4 2.8 3.9 4.3 1.4 0.9 8.6 4.4 1.5 1.3 6.0 2.3 5.7 3.2 2.7 1.9 3.1 1.0 1.3 3.4 2.0 2.3 3.3 2.4 3.7 2.3 0.0 0.4 1.1 0.4 3.8 0.6 0.5 4.6 7.8 2.7 3.5 1.7 2.8 1.1 3.7 1.5 4.3 1.3 4.6 4.6 1.4 1.3 1.7 2.0 0.4 1.4 1.5 2.5 2.0 4.2 4.9 4.1 2.3 0.0 2.9 4.4 11.9 0.2 6.8 2.0 0.0 0.0 2.0 2.3 1.4 0.0 2.4 1.1 3.4 0.6 0.9 9.4 1.5 2.1 0.5 3.4 0.1 0.1 0.4 0.9 5.8 0.8 0.7 2.0 2.2 2.9 1.7 1.1 0.3 1.9 2.9 1.3 1.0 0.6 1.9 3.4 2.3 1.9 0.7 3.3 2.4 PARP14 "KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680618-122730840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 21.6 10.3 5.6 15.8 7.2 11.7 9.3 2.3 6.0 11.6 13.3 5.9 6.4 11.4 10.6 12.7 11.7 7.2 10.0 6.5 5.2 4.8 13.7 21.5 26.0 16.7 7.3 5.2 10.0 6.7 7.2 6.8 17.5 6.3 12.3 6.7 7.5 8.5 5.5 5.2 5.7 22.3 11.9 6.8 29.7 7.6 4.6 4.9 18.7 20.4 6.4 18.9 12.8 12.4 15.9 4.2 20.8 10.5 7.4 7.0 2.8 5.9 4.9 3.1 3.3 4.4 10.6 0.0 2.3 15.5 29.2 45.1 2.6 11.7 0.0 9.7 5.1 4.6 4.6 4.7 6.0 9.0 0.5 5.4 2.3 4.0 10.8 2.4 2.7 6.4 2.4 5.1 2.0 12.6 2.5 8.8 1.0 3.0 9.1 1.6 0.4 4.2 12.7 3.2 1.6 7.1 6.1 0.2 0.0 5.9 1.3 6.6 2.2 4.3 8.6 1.5 3.9 0.9 2.1 3.4 0.6 1.0 4.7 5.7 2.7 8.3 8.2 4.0 6.9 10.5 6.0 10.2 3.8 4.5 4.2 15.9 3.2 3.4 20.8 7.4 9.3 0.6 7.0 2.8 5.6 7.2 2.3 6.0 5.2 4.8 7.3 5.2 6.3 4.9 PARP15 "FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577602-122639047 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.9;lymphoid tissue: 40.4" "Cell line enhanced" "Detected in some" "HEL: 10.7;REH: 5.0;THP-1: 5.1;TIME: 12.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 9.3;MAIT T-cell: 6.5;memory B-cell: 11.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 6.4;naive B-cell: 11.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 5.9;NK-cell: 5.2;T-reg: 4.5" "Group enriched" "Detected in many" 6 "B-cells: 11.9;NK-cells: 5.2;T-cells: 9.3" "Low region specificity" "Detected in many" HPA035757 Approved Mitochondria "Intracellular and membrane" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 2.4 0.9 0.5 24.5 0.4 9.8 1.3 0.3 0.8 1.2 2.8 1.2 0.5 1.0 1.5 2.3 1.9 1.4 2.8 1.5 0.6 0.5 1.5 1.9 5.6 20.3 0.6 0.6 1.1 2.7 0.0 1.0 1.0 0.6 1.3 2.1 1.8 5.5 0.2 2.6 0.7 22.9 0.9 0.9 40.4 1.7 1.7 0.4 9.4 1.9 1.7 34.8 3.6 1.2 11.9 1.2 1.3 0.6 5.2 9.3 2.7 0.6 0.2 0.5 0.5 0.2 0.3 0.6 0.3 0.2 0.1 0.1 0.3 1.0 0.8 0.6 0.2 0.6 0.1 0.0 0.0 1.9 0.2 10.7 0.8 0.5 0.2 0.7 0.5 2.2 0.1 0.4 0.2 2.4 0.3 2.1 0.0 0.5 3.2 0.7 0.7 0.3 5.0 0.4 0.6 0.0 1.0 0.8 0.5 0.3 0.2 0.3 0.8 5.1 12.7 0.4 1.1 0.5 0.4 1.0 0.7 2.4 0.7 0.3 0.2 1.3 0.2 0.1 9.3 0.5 6.5 11.2 5.0 6.4 0.9 11.9 4.3 5.9 0.7 5.2 0.6 1.2 4.5 2.7 0.5 0.4 0.3 0.8 0.6 0.5 0.6 0.6 0.6 0.4 PARP16 "C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Enzymes, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" 8.9 14.2 12.0 13.1 11.6 8.0 20.4 32.2 17.7 18.6 12.8 5.6 11.9 9.3 13.1 8.5 10.5 12.0 8.7 7.2 9.7 5.3 9.0 18.1 11.5 14.0 11.5 6.2 17.6 11.3 12.7 8.5 9.2 9.1 11.5 10.4 7.5 10.3 21.4 5.4 10.8 9.7 17.7 8.0 9.3 11.0 7.6 12.0 15.1 9.5 6.3 12.4 14.0 25.6 10.1 4.4 14.1 5.3 10.3 14.2 6.0 3.8 4.0 4.4 6.9 3.6 3.8 1.9 1.7 4.7 5.0 5.2 3.2 3.5 12.5 4.9 2.2 6.3 20.3 2.5 3.7 4.5 8.1 2.1 4.3 4.5 6.8 5.7 4.0 4.4 4.2 1.3 5.1 4.6 5.1 4.8 4.3 4.6 11.8 6.1 2.0 5.4 21.9 8.0 9.5 3.5 3.5 7.6 5.1 5.5 5.3 4.5 6.2 5.2 1.8 5.9 4.5 3.3 2.7 8.9 10.5 16.4 4.9 8.5 2.7 14.1 3.3 10.0 11.6 5.3 12.9 7.8 11.2 11.8 4.4 10.1 14.2 10.5 13.0 10.3 5.2 3.9 9.2 6.0 12.0 11.6 32.2 17.7 9.7 5.3 11.5 6.2 9.1 12.0 PARP2 ADPRTL2 ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343582-20357905 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA052003: " "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavourable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 11.5 16.6 23.6 8.9 28.5 20.9 15.2 36.7 31.3 12.0 11.7 16.8 9.3 11.2 18.8 16.8 10.7 14.7 8.9 14.0 19.2 17.8 14.0 15.0 12.0 11.8 16.6 30.8 20.2 11.8 11.6 14.6 11.3 22.1 11.3 12.9 10.8 10.5 12.9 25.9 15.1 10.8 14.6 13.9 11.4 11.6 20.4 17.4 6.0 11.7 13.9 15.2 9.3 10.4 6.7 5.6 1.8 5.0 6.9 12.3 4.9 20.2 14.8 22.8 17.1 7.6 7.2 16.6 22.5 12.3 28.6 35.5 13.9 19.4 15.0 10.2 7.1 19.0 30.3 10.3 33.9 12.0 14.8 13.7 17.9 23.3 6.8 28.3 7.9 5.0 8.8 17.8 19.7 14.7 14.5 20.5 19.6 12.5 14.5 12.2 12.5 23.1 18.2 31.0 9.7 11.4 10.6 15.8 10.9 25.1 14.0 6.6 12.9 9.6 10.0 17.5 26.5 12.0 18.2 19.2 24.5 19.9 7.3 12.6 19.3 1.8 5.0 0.5 9.5 4.5 12.3 6.7 8.9 8.3 5.4 4.6 9.6 9.3 0.1 6.9 2.5 5.6 5.2 4.9 23.6 28.5 36.7 31.3 19.2 17.8 16.6 30.8 22.1 17.4 PARP3 "ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: " "prognostic favourable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favourable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 15.2 29.2 11.2 14.6 17.1 2.8 13.6 5.7 18.8 7.5 17.3 10.6 14.3 26.9 10.3 14.1 10.8 12.1 16.2 12.4 11.6 12.3 17.3 22.3 13.3 9.7 12.0 14.2 8.2 3.9 34.2 9.8 6.2 12.2 12.1 10.7 13.2 14.0 18.1 14.6 6.1 26.3 18.9 8.7 12.8 15.8 4.5 10.2 2.9 17.0 9.6 10.3 15.1 8.9 9.0 2.9 1.7 4.1 6.6 4.9 2.3 6.0 3.3 1.0 9.0 8.7 16.5 2.5 9.8 15.9 12.2 13.7 1.9 15.9 8.2 2.6 16.2 0.9 2.5 8.9 5.9 20.0 0.6 4.2 6.7 6.3 9.5 2.5 5.8 13.1 5.5 7.7 5.2 6.1 1.7 7.7 9.3 1.5 2.2 6.3 1.3 9.6 3.5 1.5 7.0 7.4 6.6 1.0 3.4 9.9 2.8 5.3 3.4 2.8 13.7 24.5 5.1 3.6 5.9 11.8 14.3 3.5 15.8 7.4 7.6 0.0 2.6 1.7 3.6 4.1 3.4 9.0 4.2 2.8 2.9 4.3 4.9 4.9 0.1 6.6 2.0 1.2 4.3 2.3 11.2 17.1 5.7 18.8 11.6 12.3 12.0 14.2 12.2 10.2 PARP4 "ADPRTL1, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420926-24512810 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011739 Approved Supported Cytosol Cytosol "HPA011739: AB_1854986" "unprognostic (1.61e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-2)" "unprognostic (4.35e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (4.12e-3)" "unprognostic (2.97e-2)" "prognostic favourable (1.21e-5)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.80e-2)" "unprognostic (2.84e-3)" 25.3 24.7 6.6 16.7 12.9 11.6 14.6 2.3 7.0 17.8 39.4 16.7 21.6 22.9 19.1 11.2 22.2 14.9 23.8 11.3 7.9 5.6 28.8 17.3 17.8 16.5 14.6 4.4 15.9 15.5 11.2 12.6 14.8 12.5 16.1 24.1 14.0 17.7 30.9 6.5 10.2 49.9 15.5 20.5 28.4 20.4 7.0 12.1 28.8 18.2 11.3 26.2 23.3 13.2 9.0 16.4 26.1 18.6 11.8 12.9 10.6 15.0 13.5 6.6 11.9 18.3 26.1 5.6 17.5 23.0 15.4 13.8 5.5 39.2 11.2 17.5 15.9 17.5 9.8 17.7 12.6 25.8 6.9 16.1 12.5 12.6 10.4 20.6 16.0 15.0 6.0 12.7 6.8 25.2 4.5 5.0 18.2 6.9 13.0 9.9 7.5 16.7 12.3 12.4 15.8 28.6 31.0 6.0 7.7 12.8 5.2 12.1 2.5 17.1 35.7 7.0 7.3 8.9 17.8 5.7 6.6 14.8 12.7 10.9 15.2 25.2 12.4 26.1 12.9 15.3 12.9 9.0 10.8 12.8 16.4 5.1 8.1 9.6 14.3 11.8 18.6 6.2 12.7 10.6 6.6 12.9 2.3 7.0 7.9 5.6 14.6 4.4 12.5 12.1 PARP6 pART17 ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favourable (3.17e-5)" "prognostic unfavourable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavourable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 13.7 16.6 28.0 12.8 32.4 25.1 26.5 46.6 41.2 15.5 16.2 16.9 18.2 14.1 23.3 23.8 14.0 17.0 20.2 18.4 26.1 22.4 14.3 9.0 15.7 16.8 19.9 21.8 26.3 20.9 20.6 30.8 17.0 19.4 19.3 14.3 14.5 21.3 18.8 23.9 20.3 14.4 19.6 14.2 18.2 18.2 25.1 15.8 9.6 21.7 12.5 15.8 16.3 15.8 4.1 4.0 12.1 5.3 4.3 4.3 2.9 7.2 13.1 13.8 17.9 14.8 12.4 11.2 6.2 9.4 10.3 15.2 8.6 13.2 10.0 3.9 9.4 9.5 15.2 8.4 5.9 11.8 13.7 14.5 22.9 0.1 12.4 7.4 13.9 15.9 20.8 9.6 26.6 6.9 7.3 11.5 8.3 13.2 6.3 13.1 6.4 0.0 11.8 9.8 7.8 9.6 14.4 39.0 20.7 10.4 8.5 17.0 10.8 8.6 6.5 13.0 11.9 16.9 9.4 13.0 11.9 10.8 9.4 14.6 9.0 1.7 5.3 12.1 3.8 4.4 2.7 3.3 2.7 4.0 4.0 4.1 4.3 3.2 5.7 4.3 4.9 3.1 4.2 2.9 28.0 32.4 46.6 41.2 26.1 22.4 19.9 21.8 19.4 15.8 PARP8 "FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846522 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: " "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favourable (1.12e-4)" 6.2 7.8 8.8 17.1 9.5 33.5 5.3 2.4 18.7 5.6 5.5 3.3 0.6 6.8 5.2 5.4 5.2 7.4 12.3 3.6 12.8 8.0 5.8 4.2 10.9 18.2 4.9 11.0 5.9 7.1 9.8 14.4 5.6 5.4 6.1 4.3 4.1 7.6 4.2 1.7 4.2 14.2 5.4 7.0 20.1 10.2 6.4 2.8 9.9 21.9 1.1 12.3 8.8 7.0 7.1 3.9 13.1 5.9 15.5 32.0 9.5 11.7 0.0 5.4 8.6 1.5 2.7 8.6 1.9 7.0 1.9 5.6 0.3 15.4 6.9 8.2 0.2 5.8 0.9 5.9 4.5 9.7 7.5 5.1 4.7 0.5 2.9 11.9 0.1 3.3 4.9 3.8 2.7 0.1 0.7 4.2 2.6 3.8 14.3 15.1 5.8 2.9 7.2 11.5 8.0 3.5 5.8 6.0 9.3 6.3 10.3 1.6 0.4 42.2 0.0 0.4 7.3 0.5 5.7 3.1 0.1 13.5 6.5 3.4 8.0 10.3 5.9 13.1 20.6 1.6 32.0 6.0 16.1 23.0 3.9 7.1 10.0 16.7 12.3 15.5 1.1 1.8 9.5 9.5 8.8 9.5 2.4 18.7 12.8 8.0 4.9 11.0 5.4 2.8 PARP9 "BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 34.9;BJ hTERT+ SV40 Large T+ RasG12V: 41.8;SK-MEL-30: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Cytosol" Mitochondria "HPA066708: " "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favourable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 27.1 20.2 8.7 17.2 12.4 9.1 13.8 2.9 13.9 13.1 13.1 9.9 7.4 10.4 23.3 10.1 15.6 12.3 14.9 8.5 7.4 6.0 17.8 38.6 18.9 17.5 8.5 6.0 12.1 14.4 16.0 20.3 11.9 10.3 15.1 10.1 11.5 19.1 6.6 8.6 5.7 21.2 14.8 16.3 27.3 11.1 5.4 10.3 21.8 17.5 9.0 19.1 13.7 9.8 7.3 11.9 38.2 18.0 13.0 10.6 9.1 8.0 2.7 1.0 0.7 6.2 13.0 0.9 2.7 14.7 34.9 41.8 4.2 8.9 1.8 6.0 5.4 8.9 2.3 4.8 7.3 13.9 1.6 8.7 2.8 2.2 6.7 2.8 5.8 10.5 4.7 4.9 1.2 7.4 0.8 7.5 1.4 3.5 8.9 3.5 0.4 7.6 9.5 9.9 0.6 13.4 4.6 0.6 2.4 7.1 1.2 32.3 3.8 3.1 4.4 1.5 4.4 0.3 1.6 4.6 2.4 3.3 5.2 3.0 2.7 14.4 12.7 15.3 9.2 17.7 8.6 7.3 9.8 10.3 11.9 5.0 7.5 9.1 38.2 13.0 18.0 1.4 10.6 9.1 8.7 12.4 2.9 13.9 7.4 6.0 8.5 6.0 10.3 10.3 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 4.9 6.7 9.1 11.5 0.7 1.4 12.1 4.8 1.5 4.4 6.2 5.4 5.0 2.6 1.0 1.1 12.5 10.3 4.1 3.2 10.4 9.7 7.1 12.4 9.6 0.5 9.7 11.2 0.6 3.3 4.6 1.3 3.1 9.2 3.5 3.1 5.6 11.5 10.2 10.1 4.1 18.3 9.2 3.2 1.7 11.2 16.1 4.9 2.8 5.5 2.1 4.6 7.0 4.1 6.1 5.5 7.7 6.4 4.8 4.8 12.2 3.8 7.3 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Cell line enhanced" "Detected in many" "A-431: 60.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavourable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavourable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 60.7 19.8 19.5 12.3 1.9 3.4 8.2 27.9 13.3 28.8 24.3 6.9 11.3 32.4 9.9 10.7 16.1 18.7 9.4 31.6 7.9 10.2 7.8 14.1 10.0 0.1 5.0 11.6 0.9 7.7 13.3 7.1 14.5 11.4 21.8 33.9 6.9 19.2 5.9 3.5 17.2 12.0 27.2 8.7 10.8 9.4 7.7 12.1 10.4 12.2 15.6 12.9 7.7 8.4 18.9 45.6 23.9 29.6 3.1 8.6 15.0 11.5 8.9 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol 8200000 Cytosol "HPA003239: AB_1079580" "prognostic unfavourable (4.02e-7)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavourable (1.88e-4)" "prognostic unfavourable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavourable (6.38e-4)" 19.1 18.4 35.7 13.0 43.0 28.5 19.3 33.5 58.3 20.2 16.9 19.2 12.4 14.7 16.0 22.2 17.9 15.8 11.0 43.9 35.0 38.8 21.3 29.5 15.1 14.6 35.1 46.0 16.2 14.6 16.4 15.5 17.2 57.4 22.1 18.1 11.6 17.2 21.4 69.5 14.7 13.6 19.6 28.6 12.0 12.7 29.1 19.2 18.1 19.3 15.9 17.9 14.4 13.7 31.6 53.0 51.2 58.0 30.0 37.4 51.6 21.4 17.0 17.4 21.8 37.5 31.0 19.4 35.3 20.2 28.1 35.5 49.3 16.4 27.2 30.0 29.8 26.8 29.9 35.2 40.6 18.9 43.3 41.5 32.0 48.2 25.1 49.4 51.1 15.4 26.1 32.0 34.6 26.5 59.3 26.7 33.5 63.9 24.0 37.7 14.2 19.1 19.9 22.6 19.5 27.3 15.8 33.2 12.8 26.8 42.8 22.9 25.9 35.2 19.7 16.6 21.0 31.4 38.3 16.9 26.2 27.8 26.1 33.0 32.8 40.0 58.0 51.2 30.2 53.6 30.1 31.6 30.6 32.7 53.0 24.2 28.5 32.5 30.8 30.0 52.2 23.9 37.4 51.6 35.7 43.0 33.5 58.3 35.0 38.8 35.1 46.0 57.4 19.2 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm Nucleoplasm "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 24.8 22.2 15.3 19.9 18.7 25.8 18.0 14.2 17.8 13.6 25.3 23.0 21.1 41.1 18.2 18.7 25.2 15.0 19.8 36.0 14.8 13.8 20.2 17.8 18.7 15.6 16.6 14.1 15.6 13.9 16.0 12.1 14.2 20.5 13.3 16.5 14.4 17.1 19.2 45.8 32.8 37.2 19.5 18.3 23.4 18.1 19.4 18.6 13.2 14.8 28.0 19.0 17.6 16.7 7.8 8.7 20.5 9.8 7.9 13.5 4.6 28.2 11.4 8.0 11.7 16.4 18.3 12.1 21.6 15.4 18.6 16.4 27.8 10.3 7.2 72.5 24.7 22.1 12.7 16.6 15.9 13.2 8.9 20.8 12.0 11.8 14.7 10.0 17.9 15.4 12.7 18.0 12.9 19.9 11.6 16.2 18.5 23.8 6.2 5.3 6.9 17.0 10.4 10.2 11.6 11.4 15.9 7.8 5.8 14.6 25.3 14.0 37.1 12.5 29.6 14.8 8.2 20.1 29.2 15.0 28.6 13.4 22.7 14.0 18.6 7.5 8.7 9.2 9.6 9.2 8.0 7.8 7.2 10.2 8.7 5.7 4.6 6.8 20.5 7.9 9.8 5.6 13.5 4.6 15.3 18.7 14.2 17.8 14.8 13.8 16.6 14.1 20.5 18.6 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 15.6" "Cell line enhanced" "Detected in some" "AF22: 8.2;CACO-2: 17.6;HEL: 21.6;Hep G2: 9.0;NTERA-2: 9.3;SCLC-21H: 6.4" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 2.7;neutrophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.8 1.1 12.0 1.1 11.4 2.0 1.0 3.1 23.9 1.6 1.1 13.7 2.3 1.3 3.2 1.7 2.8 5.7 1.7 4.2 10.0 6.0 1.0 0.6 2.1 0.6 7.8 10.5 4.0 3.1 0.7 1.4 3.6 10.7 2.3 1.3 2.1 1.0 6.4 0.7 0.7 1.1 6.1 10.3 1.0 0.9 15.6 8.7 0.0 0.6 0.0 0.7 0.9 0.4 0.4 0.5 2.7 0.5 0.6 0.2 1.4 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 17.6 0.0 0.0 4.6 0.0 0.9 3.8 0.0 0.0 0.0 0.1 21.6 0.0 9.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.5 9.3 0.0 0.0 1.1 0.0 0.0 0.0 6.4 5.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.2 0.6 0.2 2.7 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.2 0.2 2.2 0.6 0.5 0.5 0.2 1.4 12.0 11.4 3.1 11.3 10.0 6.0 7.8 10.5 10.7 8.7 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900965-81911464 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 70.8" "Cell line enhanced" "Detected in all" "Hep G2: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Supported "Intermediate filaments,Centrosome" 7000 Centrosome "Intermediate filaments" "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favourable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 13.6 5.5 13.3 5.7 12.7 5.3 10.4 12.2 17.0 6.5 16.2 13.4 6.4 30.7 5.8 8.6 7.6 12.2 8.0 17.7 14.0 11.8 21.7 46.5 7.2 6.3 13.4 16.0 7.8 11.5 8.2 4.6 6.0 15.9 10.1 8.5 5.8 10.8 6.6 13.5 4.5 26.5 5.0 14.3 4.1 11.5 70.8 11.0 5.6 6.7 6.8 5.8 7.5 4.4 7.3 6.6 2.1 3.5 4.7 8.4 4.0 12.1 7.0 5.6 15.8 28.2 14.9 8.3 8.7 18.8 12.3 14.6 27.4 12.7 4.2 4.8 9.1 10.0 8.5 16.2 7.1 1.2 6.9 9.2 9.6 62.6 30.2 9.2 7.7 12.2 9.4 11.1 8.6 11.3 17.0 8.8 9.1 10.3 10.9 11.4 4.5 7.5 7.2 6.0 15.0 14.7 23.0 7.2 6.6 6.6 36.4 8.5 10.1 21.9 7.6 9.1 6.0 6.8 7.2 5.7 2.4 4.1 9.4 12.4 8.9 2.1 3.5 1.2 7.1 3.4 4.6 6.0 8.4 7.2 6.6 7.3 7.0 7.2 1.0 4.7 3.0 6.5 5.0 4.0 13.3 12.7 12.2 17.0 14.0 11.8 13.4 16.0 15.9 11.0 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229097-54298247 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 81.5" "Cell line enhanced" "Detected in some" "ASC diff: 81.0;ASC TERT1: 37.9;BJ hTERT+: 47.0;fHDF/TERT166: 32.7;HHSteC: 27.4;HSkMC: 68.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" 150000 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: " "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favourable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavourable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 35.0 12.4 12.6 16.1 7.6 0.9 17.2 2.4 20.1 33.2 19.1 9.2 6.4 9.6 27.6 14.6 21.9 22.5 16.2 15.3 8.9 7.4 22.8 8.4 24.1 26.9 9.2 4.0 81.5 6.8 1.6 2.1 25.1 7.2 18.6 15.2 19.2 8.5 8.3 11.9 7.0 17.4 19.7 8.8 51.6 13.6 19.0 9.3 0.5 11.3 12.8 4.3 35.9 24.6 0.9 0.4 2.5 0.4 0.3 0.8 0.3 0.0 0.0 0.2 0.1 81.0 37.9 0.1 4.2 47.0 0.0 0.1 11.2 0.0 0.1 0.1 32.7 0.1 3.2 0.0 0.0 0.4 0.1 0.1 0.1 0.2 27.4 0.0 0.0 68.9 0.0 5.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.3 0.1 6.6 0.0 0.1 0.0 0.1 0.0 0.1 14.8 0.5 16.2 0.0 0.0 0.0 0.1 0.4 0.0 0.3 2.5 0.4 0.2 0.5 0.2 0.2 0.6 0.8 0.4 0.0 0.9 0.7 0.4 2.3 0.3 0.3 0.4 0.2 0.3 12.6 7.6 2.4 7.3 8.9 7.4 9.2 4.0 7.2 9.3 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113837-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 169.0;ASC TERT1: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.9;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 8 "monocytes: 4.1;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" 35000000 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavourable (8.11e-4)" 61.8 10.4 8.3 11.0 9.1 0.5 66.1 4.6 10.4 73.1 15.7 6.7 6.9 5.1 44.3 17.3 21.7 26.1 51.7 24.2 8.2 3.9 17.0 4.6 28.9 21.5 7.9 8.1 46.5 7.5 10.4 7.7 46.4 7.7 24.2 6.3 22.9 11.2 19.3 29.8 20.3 11.2 29.8 5.0 19.6 9.2 21.5 6.7 1.4 21.4 16.0 7.3 23.6 35.1 0.4 0.1 0.0 4.1 0.0 2.9 0.6 0.0 0.0 1.0 0.0 169.0 58.5 0.3 5.9 24.5 4.1 7.0 0.6 0.0 0.0 0.7 16.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.4 24.0 0.0 0.0 26.3 0.0 5.7 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 2.2 2.8 0.3 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 2.9 0.6 0.0 0.4 0.1 0.8 0.1 0.1 0.0 1.3 0.0 0.0 4.1 0.0 0.0 0.6 8.3 9.1 4.6 10.4 8.2 3.9 7.9 8.1 7.7 6.7 PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" 7.0 6.0 8.6 6.2 12.3 19.9 11.5 17.8 15.9 8.6 8.9 7.1 7.6 9.5 7.8 6.4 11.4 7.5 5.8 4.8 8.5 10.6 8.5 11.3 6.7 8.0 9.3 9.9 10.2 15.3 10.7 9.9 5.6 11.5 6.8 10.6 6.1 10.2 8.9 7.7 9.4 9.7 6.5 8.3 8.3 10.2 7.8 9.3 19.1 22.2 6.7 8.8 8.8 8.0 6.7 9.3 11.0 6.1 5.6 10.4 5.2 5.5 2.1 5.8 7.3 2.2 3.0 1.9 1.4 2.0 3.7 2.4 1.4 7.9 11.6 4.2 2.1 4.1 7.8 2.9 3.6 4.1 5.2 10.3 3.3 1.5 3.4 10.8 6.2 1.6 4.2 3.3 6.7 3.3 12.2 11.6 1.2 3.1 15.7 4.8 2.6 3.1 8.4 5.3 13.9 2.5 4.3 9.3 7.9 5.6 7.1 7.2 4.0 3.7 3.1 4.1 3.6 5.2 4.5 17.3 17.1 8.8 4.3 13.4 3.8 11.0 5.0 4.2 6.7 4.6 6.2 6.7 9.4 7.4 9.3 5.6 10.0 8.0 0.5 5.6 6.1 3.5 10.4 5.2 8.6 12.3 17.8 15.9 8.5 10.6 9.3 9.9 11.5 9.3 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 31.3;U-87 MG: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 5.9;granulocytes: 16.0;T-cells: 15.8" "Low region specificity" "Detected in all" "CAB017554, HPA027376, HPA059083" Approved Approved Nucleoli,Mitochondria 22000 "Nucleoli, Mitochondria" "CAB017554: AB_2161138, HPA027376: AB_1855139, HPA059083: " "unprognostic (2.14e-1)" "prognostic unfavourable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavourable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 9.9 16.2 6.8 11.0 10.5 13.4 16.7 7.1 15.6 7.3 15.3 3.3 2.9 15.5 5.4 8.0 11.2 4.4 5.8 27.6 6.9 5.2 6.8 14.2 6.1 21.4 7.2 5.2 19.5 7.2 3.4 7.5 7.9 7.2 6.5 13.1 7.6 14.1 7.6 9.6 24.7 8.4 5.2 10.7 14.2 12.5 11.0 6.7 10.3 5.1 5.0 20.8 18.0 9.8 5.9 2.3 16.0 2.2 1.4 15.8 6.2 14.1 0.6 3.7 9.1 1.5 2.3 5.2 12.5 10.1 6.3 13.4 3.6 3.0 13.5 6.9 3.8 6.2 2.5 7.8 20.1 2.7 5.0 16.4 3.3 4.2 2.7 8.1 6.1 2.9 2.8 4.3 7.3 3.3 3.4 9.3 8.3 1.4 5.1 10.2 8.9 3.9 5.4 6.0 21.7 3.2 4.6 6.9 7.9 3.2 3.8 4.7 2.4 3.4 3.8 10.0 3.2 5.2 3.3 31.3 18.1 11.1 32.0 5.9 2.0 12.2 2.2 16.0 2.5 1.5 3.0 4.7 4.2 2.8 2.3 5.9 15.8 9.6 8.5 1.4 1.9 0.4 8.0 6.2 6.8 10.5 7.1 15.6 6.9 5.2 7.2 5.2 7.2 6.7 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favourable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.4 11.3 10.1 11.9 9.0 1.2 7.1 10.5 10.6 10.3 0.9 7.1 8.2 11.9 19.8 3.1 7.5 2.8 10.5 16.5 10.4 7.3 9.2 6.9 6.4 0.0 8.0 18.9 11.0 6.9 0.5 9.2 2.9 8.2 6.0 8.3 6.1 0.0 2.4 9.1 9.2 25.2 11.1 5.8 5.5 7.5 11.4 10.0 3.2 4.7 18.5 7.3 4.7 12.5 10.3 8.5 5.1 16.2 15.3 4.4 18.3 2.6 8.0 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465221-24539837 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria Mitochondria Nucleoli "HPA046583: , HPA072492: " "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 9.6 5.6 5.7 9.8 17.3 16.3 12.8 3.3 23.6 8.0 14.7 5.5 5.6 13.6 7.3 15.7 9.5 13.2 7.0 16.9 12.5 6.8 13.7 11.1 11.2 13.4 6.2 13.7 11.0 7.3 12.8 14.1 7.7 14.9 8.3 10.1 9.9 19.3 5.2 3.9 14.2 15.6 8.6 6.1 17.9 12.7 23.1 4.8 12.5 6.2 4.1 14.9 10.3 9.2 4.5 7.2 36.4 10.9 7.1 11.0 6.7 9.0 4.6 3.9 6.5 0.1 0.0 4.1 2.7 2.4 3.7 6.5 0.4 11.0 9.1 1.8 0.7 2.0 11.3 6.9 9.9 7.8 5.4 4.9 5.3 2.6 1.3 4.1 4.8 0.7 3.0 0.9 0.9 5.5 0.9 13.9 0.5 16.9 7.8 5.4 7.0 5.4 4.0 7.0 13.4 3.2 17.6 2.5 3.2 14.7 6.0 4.5 8.2 1.6 0.1 2.6 3.8 4.8 3.2 8.9 6.8 11.0 7.1 6.4 5.3 9.4 8.9 21.3 7.6 10.9 11.0 4.5 6.2 6.2 7.2 4.1 4.9 5.7 36.4 7.1 10.4 2.3 5.1 6.7 5.7 17.3 3.3 23.6 12.5 6.8 6.2 13.7 14.9 4.8 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell line enriched" "Detected in some" 7 "ASC diff: 104.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056731 Approved "HPA056731: " "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 7.8 0.3 2.0 104.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.3 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.0 0.5 0.1 0.5 0.0 0.6 1.6 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199, HPA068961" Supported Approved Vesicles Vesicles "CAB004272: AB_626657, HPA035199: , HPA068961: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favourable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.4 10.8 13.5 9.0 14.0 11.7 14.3 14.0 9.1 12.6 10.6 10.8 10.1 13.9 9.6 13.6 13.4 16.1 10.1 12.0 24.7 10.9 7.3 14.3 17.9 12.2 12.1 19.4 10.6 18.6 13.5 9.1 11.5 13.6 11.3 14.7 17.8 12.2 8.5 8.5 9.7 25.0 13.5 12.5 12.2 7.5 21.3 11.0 18.2 21.0 7.5 19.4 15.3 14.1 13.8 13.7 13.4 12.1 15.1 14.3 21.7 6.6 8.4 11.9 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 PDSS1 "COQ1, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697659-26746798 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 22.4;lymphoid tissue: 31.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol Cytosol "HPA038032: AB_10670650, HPA042741: " "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavourable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavourable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" 3.1 2.6 2.4 7.0 3.1 5.6 3.5 5.6 5.1 3.1 18.2 1.5 1.2 20.6 3.8 2.1 8.3 3.4 3.7 4.2 2.2 2.2 8.6 7.2 4.0 7.8 2.1 2.3 2.8 3.8 1.7 2.5 2.8 2.9 2.3 17.0 3.2 3.5 1.8 10.4 2.7 22.4 3.6 3.1 5.7 3.8 3.0 1.6 31.8 2.1 4.7 5.0 2.9 4.0 3.2 5.2 0.9 5.3 0.8 3.4 1.3 7.5 5.9 4.5 8.2 1.5 2.8 6.2 7.0 1.8 10.2 7.0 9.0 4.2 17.3 3.7 3.4 9.6 14.3 10.7 8.7 7.2 12.0 14.9 5.1 6.5 2.2 9.9 5.9 3.5 4.6 9.5 2.5 5.3 13.7 4.6 7.1 11.9 31.2 7.0 9.0 5.7 14.5 12.9 12.5 6.0 3.6 13.2 8.1 6.8 14.0 7.6 4.9 11.6 3.4 5.7 9.1 11.7 11.1 1.8 6.7 12.6 5.6 25.2 4.4 0.0 5.3 0.9 0.9 4.1 2.1 0.5 1.8 1.3 5.2 3.2 3.4 1.5 0.3 0.8 2.1 1.4 0.1 1.3 2.4 3.1 5.6 5.1 2.2 2.2 2.1 2.3 2.9 1.6 PDSS2 "bA59I9.3, C6orf210" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152557-107459564 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Enhanced Cytosol Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavourable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favourable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favourable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 10.6 27.3 7.2 17.0 8.3 8.3 19.6 9.0 10.3 10.4 12.7 9.0 13.7 9.6 13.1 11.4 11.5 9.2 11.2 16.0 7.0 6.8 22.1 27.4 18.2 18.3 9.2 5.3 10.8 14.0 11.4 19.4 7.0 9.6 15.6 13.9 12.0 19.9 19.9 13.1 9.0 10.1 11.0 8.1 9.1 10.5 12.8 10.1 11.3 14.1 11.1 10.6 10.9 12.9 8.5 9.4 4.1 12.1 4.6 8.3 4.3 5.6 7.6 6.5 10.1 11.3 14.5 15.0 10.0 12.7 9.6 9.3 7.5 8.2 10.8 9.2 11.1 7.8 15.7 12.5 13.2 6.9 7.7 10.7 9.0 12.5 12.0 13.8 8.7 10.7 14.9 15.2 12.1 10.1 15.2 14.7 9.4 7.0 4.0 14.6 4.1 9.9 7.2 5.8 8.7 11.9 7.8 6.4 5.6 6.8 12.0 14.3 9.8 16.7 6.3 6.9 4.1 9.6 8.5 4.1 5.0 8.4 12.8 20.6 12.6 4.1 6.6 3.5 5.3 7.6 8.3 6.6 5.6 6.8 9.4 8.5 7.3 6.9 0.9 4.6 12.1 4.5 7.1 4.3 7.2 8.3 9.0 10.3 7.0 6.8 9.2 5.3 9.6 10.1 PDXK "C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79" ENSG00000160209 "Pyridoxal kinase" O00764 21 43719094-43762307 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 68.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030196, HPA030197, HPA030198, CAB033918" Enhanced Enhanced Nucleoplasm 870000 Nucleoplasm "CAB033918: AB_2162502, HPA030196: AB_10599735, HPA030197: AB_10601792, HPA030198: AB_10603570" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.88e-2)" "unprognostic (1.87e-1)" "unprognostic (8.29e-2)" "unprognostic (4.31e-3)" "unprognostic (3.64e-3)" "unprognostic (1.32e-1)" "unprognostic (8.66e-2)" "unprognostic (9.34e-2)" "unprognostic (2.10e-1)" "unprognostic (3.54e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.51e-3)" 28.1 13.2 37.4 8.7 36.6 13.3 13.3 21.9 38.5 9.7 13.8 11.0 15.7 16.7 9.0 13.2 11.0 12.9 8.8 11.4 26.1 30.4 22.8 17.4 20.4 9.5 24.1 22.7 16.4 17.6 25.7 20.7 12.6 20.3 10.6 11.8 7.8 18.3 13.9 5.8 14.3 22.1 8.8 10.1 7.8 15.2 68.9 10.7 3.9 13.6 7.0 11.0 9.7 8.6 2.7 2.5 1.3 7.7 1.9 3.3 2.4 17.2 21.2 3.4 6.4 8.3 11.8 4.1 6.2 9.8 6.1 5.1 17.2 27.1 5.8 6.7 8.9 13.1 6.5 17.8 4.0 6.5 5.6 5.9 23.2 12.7 16.4 5.5 8.7 16.7 17.0 6.4 7.1 2.8 10.3 13.5 5.7 11.7 0.8 10.1 9.2 8.1 6.6 2.0 16.2 26.3 21.2 3.3 3.9 25.9 24.0 9.2 7.9 7.8 5.1 4.4 8.7 5.9 5.8 8.2 3.8 3.4 18.3 16.1 4.3 1.3 4.8 0.2 1.7 4.4 3.3 1.4 1.7 1.9 2.5 2.7 2.0 1.4 1.3 1.9 7.7 1.2 1.5 2.4 37.4 36.6 21.9 38.5 26.1 30.4 24.1 22.7 20.3 10.7 PDZRN3 "KIAA1095, LNX3, SEMACAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382433-73624940 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.1;ASC diff: 27.5;ASC TERT1: 14.5;BJ hTERT+: 19.6;HSkMC: 20.1;U-87 MG: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 52 "plasmacytoid DC: 5.2" "Lineage enriched" "Detected in single" 52 "dendritic cells: 5.2" "Group enriched" "Detected in many" 5 "amygdala: 12.4;basal ganglia: 7.4;cerebral cortex: 17.9;hippocampal formation: 14.5" "Low region specificity" "Detected in many" HPA038822 Approved "HPA038822: AB_10675952" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favourable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favourable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favourable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 13.0 17.4 11.5 4.8 12.9 0.0 10.3 1.7 26.8 18.7 32.6 4.5 4.6 4.3 29.0 12.4 13.6 11.6 13.1 19.8 9.1 2.5 5.3 0.9 6.3 1.9 3.6 11.2 35.1 2.9 0.3 2.2 8.1 6.8 15.4 6.9 9.7 9.7 14.9 38.3 7.5 10.2 26.3 3.8 1.0 19.3 3.4 2.9 0.2 1.6 5.1 1.1 21.3 18.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 27.5 14.5 0.0 7.8 19.6 2.4 1.5 7.4 0.0 0.0 0.0 10.5 0.0 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.0 4.6 0.0 0.0 20.1 0.0 6.5 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 2.1 0.0 0.0 4.0 0.0 0.0 0.0 1.7 5.0 0.0 3.6 5.6 2.1 0.0 0.0 9.9 0.7 11.1 1.0 0.3 0.0 0.1 14.5 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 11.5 12.9 1.7 26.8 9.1 2.5 3.6 11.2 6.8 2.9 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 21.5 6.0 14.3 8.7 13.2 9.7 12.4 8.4 14.1 15.1 9.3 12.3 6.2 7.2 16.1 8.7 6.6 7.5 12.2 18.5 12.3 7.5 6.6 4.9 20.5 7.5 13.8 8.8 9.8 5.8 7.6 4.2 19.5 9.8 8.4 10.2 13.7 7.0 9.5 8.8 8.4 9.1 14.8 10.1 41.8 6.7 11.5 15.9 2.7 8.3 9.0 5.7 10.0 12.2 0.9 0.6 1.1 0.6 5.5 1.4 0.4 2.5 3.8 9.0 2.1 17.0 18.4 3.1 14.0 9.7 7.4 7.5 3.0 2.3 2.0 2.5 20.1 1.2 7.2 2.2 8.5 2.0 3.7 3.6 5.7 1.8 6.2 2.1 1.9 14.1 2.2 14.4 2.4 20.8 4.7 2.0 7.9 1.0 1.2 2.3 4.1 1.0 2.5 5.4 1.4 2.2 4.6 2.0 2.4 5.4 1.1 9.4 0.8 1.5 25.4 15.9 7.6 6.6 5.9 3.1 4.4 2.8 2.7 5.1 8.5 0.4 0.6 1.1 0.7 0.2 1.4 0.9 0.2 0.2 0.3 0.8 0.3 0.3 0.6 5.5 0.2 0.6 0.2 0.4 14.3 13.2 8.4 14.1 12.3 7.5 13.8 8.8 9.8 15.9 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144454 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.7" "Cell line enhanced" "Detected in many" "CACO-2: 21.3;U-698: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 33.9" "Group enriched" "Detected in all" 4 "granulocytes: 33.9;monocytes: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: " "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavourable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 15.7 5.1 10.0 15.1 20.5 105.7 22.3 15.1 8.9 9.9 14.5 11.0 3.3 9.9 14.5 7.1 26.4 8.0 14.9 11.6 11.3 6.8 6.7 8.6 20.1 16.8 15.6 5.2 4.8 6.2 11.0 14.8 13.7 10.8 7.6 11.8 6.0 12.3 8.5 4.5 17.5 17.3 8.4 15.0 17.8 10.2 7.8 12.8 19.9 6.3 10.2 19.3 14.1 14.8 3.9 2.3 33.9 9.2 1.3 5.0 2.5 1.2 1.0 13.7 9.1 1.6 1.2 3.1 1.7 2.0 1.6 2.6 21.3 1.5 17.5 4.3 0.6 2.1 4.1 3.8 3.2 4.3 3.3 1.6 0.6 3.4 4.8 1.7 3.1 1.6 3.0 2.4 8.2 9.0 0.9 4.4 1.3 0.1 3.7 2.5 8.9 0.6 4.7 4.7 9.9 6.6 3.9 6.3 8.8 1.3 2.0 4.7 1.1 1.2 6.4 1.5 2.2 1.5 2.5 10.1 0.9 53.0 0.8 1.5 4.0 5.1 6.5 6.3 0.4 6.1 0.7 3.9 2.2 0.9 2.3 2.4 2.7 1.1 33.9 1.3 9.2 0.2 5.0 2.5 10.0 20.5 15.1 8.8 11.3 6.8 15.6 5.2 10.8 12.8 PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301526 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 20.7;MOLT-4: 23.2;REH: 11.4;SCLC-21H: 10.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 21.4" "Cell type enhanced" "Detected in many" "neutrophil: 9.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: " "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (9.21e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-2)" "unprognostic (3.36e-3)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "prognostic favourable (1.53e-6)" "unprognostic (3.64e-1)" "unprognostic (2.15e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" 12.3 3.3 5.2 5.6 4.6 16.5 8.7 21.4 6.5 7.5 9.4 5.4 9.7 11.1 9.3 7.1 4.7 5.9 11.5 3.4 4.6 4.5 9.7 3.1 7.3 4.8 5.2 3.9 16.0 38.9 1.7 5.5 3.3 4.4 8.2 4.2 9.2 7.6 12.4 3.8 6.5 12.6 17.7 5.8 6.6 14.1 10.0 4.2 38.2 4.9 3.4 2.6 13.3 14.9 0.9 2.0 9.0 3.0 0.5 0.8 1.1 0.0 1.9 5.5 0.0 3.1 4.6 0.1 0.7 2.5 0.5 0.0 0.1 0.4 0.1 2.6 1.5 0.5 4.2 0.0 0.2 1.3 1.5 4.7 8.5 0.0 2.6 0.7 20.7 2.9 0.2 0.0 0.0 1.0 3.5 0.1 0.6 0.0 23.2 0.2 9.0 0.7 11.4 0.3 1.0 2.2 9.3 10.9 0.0 0.5 0.0 6.1 0.0 3.8 0.3 1.6 2.8 0.5 2.6 0.4 0.0 0.6 2.9 3.2 1.6 1.4 3.0 3.5 0.5 1.6 0.8 0.2 0.6 0.3 2.0 0.9 0.4 0.3 9.0 0.5 1.2 0.5 0.0 1.1 5.2 4.6 21.4 4.4 4.6 4.5 5.2 3.9 4.4 4.2 PELI3 MGC35521 ENSG00000174516 "Pellino E3 ubiquitin protein ligase family member 3" Q8N2H9 11 66466327-66477337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033750, HPA038875, HPA062281" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles "Nucleoplasm, Vesicles" Nucleoli "CAB033750: AB_2161361, HPA038875: , HPA062281: " "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (1.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.19e-3)" "unprognostic (7.91e-3)" "prognostic favourable (8.19e-4)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.01e-2)" 6.7 9.5 14.5 3.8 17.0 1.8 7.4 19.6 33.1 7.4 8.3 6.7 6.4 4.8 10.3 9.1 10.6 8.2 10.1 7.7 17.4 13.5 4.6 3.2 7.1 4.3 13.0 12.5 15.3 9.9 21.5 8.3 3.8 15.8 11.5 2.9 6.4 10.4 22.3 10.8 11.2 4.7 11.3 6.2 5.0 5.8 6.2 7.8 0.3 8.5 2.7 3.4 9.0 11.8 3.3 3.3 1.3 6.8 1.2 3.1 1.4 15.3 6.5 5.3 4.1 8.5 3.3 4.2 4.9 6.4 4.7 4.0 9.5 3.5 3.8 4.9 5.4 8.2 3.5 6.2 1.9 7.5 3.0 1.0 5.4 2.8 5.4 0.8 7.5 3.1 7.0 4.8 1.7 0.9 1.8 6.1 2.0 9.4 3.1 2.4 3.3 6.7 10.7 3.9 4.0 2.6 4.9 6.4 3.5 2.5 7.1 16.7 8.3 4.2 2.7 4.2 6.4 18.1 4.1 5.6 3.2 2.0 8.7 2.5 3.4 1.3 2.5 0.4 2.5 1.8 2.0 2.8 2.1 3.1 3.3 3.3 2.2 1.8 0.1 1.2 6.8 1.0 2.4 1.4 14.5 17.0 19.6 33.1 17.4 13.5 13.0 12.5 15.8 7.8 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 95.7;liver: 103.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042375 Approved Approved Cytosol Cytosol "HPA042375: AB_10796905" "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favourable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 21.8 7.5 5.6 2.8 6.2 4.2 26.5 2.9 8.1 16.1 6.1 6.4 13.2 7.4 8.7 95.7 5.6 10.5 4.7 5.3 5.3 6.1 8.5 103.5 5.5 6.7 6.3 4.8 7.7 11.4 4.4 5.7 7.1 6.2 7.3 2.2 7.3 12.7 12.9 7.4 7.3 5.8 4.0 6.4 2.8 4.6 19.1 3.2 3.8 9.9 6.3 5.4 3.9 5.2 12.8 17.0 1.6 23.4 15.1 14.4 11.6 14.3 27.5 7.2 19.0 15.5 10.9 10.9 9.2 8.2 12.6 10.0 16.0 9.8 12.6 16.8 9.4 17.1 10.7 5.5 3.2 9.3 37.3 6.2 15.1 23.0 17.1 5.6 9.4 11.1 11.6 8.4 12.8 6.7 6.0 5.3 5.6 27.5 9.9 10.0 10.2 22.6 9.3 11.7 11.5 10.4 5.3 7.3 17.3 6.5 4.4 16.4 6.8 2.1 5.9 12.4 12.5 20.7 8.0 7.4 4.9 2.3 11.5 7.8 10.2 1.0 23.4 1.1 10.1 20.8 14.4 12.6 13.2 12.7 17.0 12.8 10.6 11.9 1.6 15.1 14.2 15.5 12.0 11.6 5.6 6.2 2.9 8.1 5.3 6.1 6.3 4.8 6.2 3.2 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 24.2;liver: 24.4;skeletal muscle: 48.3" "Group enriched" "Detected in some" 4 "ASC diff: 13.6;Hep G2: 5.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 24.2 0.2 0.1 1.6 0.1 0.1 13.1 0.1 0.2 0.1 1.7 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.4 24.4 0.1 1.6 0.1 0.1 0.1 0.6 0.2 0.2 0.1 0.1 0.3 0.2 0.1 1.3 0.1 48.3 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 8.3 0.6 0.2 2.0 1.5 0.1 0.0 0.7 1.3 2.1 0.3 0.3 0.2 0.4 0.6 13.6 0.3 1.0 0.0 0.1 0.2 0.0 0.8 0.2 0.6 0.2 0.1 0.5 0.1 0.3 0.4 0.4 1.1 0.4 0.1 5.4 0.0 0.1 0.5 0.2 0.6 0.1 0.4 0.0 0.1 2.1 0.2 0.7 0.6 0.3 0.3 0.3 0.5 0.2 0.1 0.0 0.4 0.4 0.2 0.5 1.5 0.2 0.4 0.0 0.1 0.1 0.5 0.4 0.2 1.1 1.7 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.2 0.7 2.1 1.5 0.2 0.0 0.0 0.8 0.0 0.8 0.0 1.3 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 13.9;plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 8 "dendritic cells: 16.7;granulocytes: 13.9" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA049975: , HPA063575: " "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favourable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.63e-4)" "unprognostic (1.86e-2)" 3.3 6.1 9.8 5.8 16.6 15.7 5.1 2.1 14.6 7.3 16.0 19.5 5.3 23.2 4.0 9.1 7.7 4.5 9.1 22.8 14.1 7.7 22.0 3.6 10.9 5.3 13.4 15.1 4.3 11.9 6.2 27.5 3.0 25.3 3.9 18.1 22.4 6.3 3.5 34.9 6.4 18.7 4.0 17.4 12.5 10.7 6.1 15.1 6.5 38.4 8.8 5.0 3.4 3.6 1.6 16.7 13.9 1.9 1.1 0.4 0.4 9.5 4.2 2.8 4.8 5.7 2.8 4.6 1.3 1.7 2.4 1.3 10.2 13.8 1.7 2.2 2.1 13.6 2.0 5.1 1.4 0.3 2.1 13.5 10.6 3.8 4.8 0.0 9.5 4.1 7.8 2.3 12.9 0.5 9.2 0.1 1.3 2.9 2.3 0.4 3.8 6.4 0.0 0.0 0.2 3.3 9.9 4.4 2.7 8.9 15.1 11.2 10.3 1.1 0.2 0.0 5.2 7.3 1.2 4.4 4.4 0.9 5.9 0.0 2.6 1.0 0.9 13.9 0.2 1.9 0.3 1.3 0.1 0.3 0.8 1.6 0.3 0.4 2.6 1.1 1.3 16.7 0.0 0.4 9.8 16.6 2.1 14.6 14.1 7.7 13.4 15.1 25.3 15.1 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.6;skeletal muscle: 135.7" "Cell line enhanced" "Detected in many" "A549: 71.1;RPTEC TERT1: 44.9;T-47d: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 20.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: " "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavourable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 105.6 9.0 16.4 25.7 17.9 77.0 43.4 8.5 29.4 6.6 8.8 29.1 10.6 7.4 9.4 6.3 13.0 14.4 22.4 5.7 16.6 13.2 22.1 11.2 15.1 12.1 19.2 12.9 8.0 8.1 4.0 10.2 7.5 20.7 5.4 3.8 19.3 9.1 20.0 135.7 11.8 6.9 6.5 36.0 12.4 6.7 4.6 16.8 3.3 2.9 4.7 10.3 10.3 10.1 1.5 3.6 20.5 7.1 0.8 4.7 2.9 5.1 71.1 5.6 4.5 21.4 2.7 3.0 7.6 5.4 5.6 8.8 3.3 18.8 8.8 5.0 3.3 16.6 6.0 12.0 6.5 10.4 4.2 5.2 3.6 1.2 1.8 5.0 7.9 1.9 4.0 9.7 2.3 10.9 3.8 3.3 4.5 8.4 3.5 4.7 5.5 5.0 8.0 2.7 3.4 44.9 2.6 5.4 2.2 5.5 6.0 10.8 46.8 6.0 13.7 5.9 5.4 0.7 9.1 6.8 2.3 8.0 16.3 5.9 9.0 2.2 5.6 5.5 1.8 7.1 4.7 1.5 3.4 2.3 3.6 1.4 2.5 2.4 20.5 0.8 4.1 2.2 3.2 2.9 16.4 17.9 8.5 16.9 16.6 13.2 19.2 12.9 20.7 16.8 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.0" "Cell line enhanced" "Detected in many" "U-87 MG: 37.1;WM-115: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.5;eosinophil: 11.4;intermediate monocyte: 7.3;neutrophil: 21.6;non-classical monocyte: 12.2" "Group enriched" "Detected in many" 6 "granulocytes: 21.6;monocytes: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli Nucleoli "HPA047719: , HPA066058: " "unprognostic (7.60e-2)" "prognostic unfavourable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavourable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 2.0 2.2 4.0 3.9 4.9 12.7 2.1 6.3 6.3 2.6 17.1 8.6 3.0 17.8 2.1 18.5 6.4 1.5 1.8 1.4 4.2 5.2 3.6 1.7 3.8 6.3 7.4 2.7 3.5 18.9 4.1 5.1 9.5 6.9 3.3 3.5 3.3 2.5 2.0 4.8 3.3 24.0 2.5 5.3 10.0 1.2 26.0 5.2 0.4 1.6 3.6 2.6 4.9 4.2 0.2 2.7 21.6 12.2 0.2 0.5 2.1 5.1 1.6 3.7 3.4 1.2 1.8 7.2 2.6 4.4 5.3 12.8 2.6 1.8 2.2 2.5 2.0 1.5 1.5 4.4 4.7 1.5 1.2 5.2 3.3 2.8 1.0 0.9 2.3 1.9 6.8 8.5 0.8 1.3 1.7 1.9 4.2 1.1 0.3 7.2 2.3 3.4 0.4 1.8 2.4 2.0 4.8 1.0 2.3 2.8 1.2 10.1 2.8 2.2 0.4 5.4 2.2 0.7 15.6 8.9 1.9 1.3 37.1 1.9 32.3 0.0 6.5 11.4 0.2 7.3 0.1 0.2 0.3 0.0 2.7 0.1 0.5 0.1 21.6 0.2 12.2 0.3 0.0 2.1 4.0 4.9 6.3 6.3 4.2 5.2 7.4 2.7 6.9 5.2 PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved 1800000 "HPA030047: AB_10602815" "unprognostic (6.21e-3)" "unprognostic (2.93e-1)" "unprognostic (4.46e-2)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (4.41e-4)" "unprognostic (5.69e-2)" "unprognostic (5.40e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-1)" "unprognostic (2.49e-1)" "unprognostic (8.06e-2)" "unprognostic (3.01e-2)" 32.0 16.7 28.0 26.0 29.5 26.4 23.1 21.3 46.0 28.3 38.7 40.9 30.1 65.5 21.3 33.5 33.5 22.8 37.5 18.4 28.8 23.4 40.3 31.3 21.0 25.2 32.4 33.0 19.5 27.1 12.3 17.1 31.9 29.1 20.2 17.2 36.3 28.8 28.5 8.3 31.1 59.3 20.5 36.1 28.1 42.7 24.0 29.1 16.4 20.4 15.4 26.0 27.2 23.9 20.3 26.9 5.2 38.0 7.7 25.2 22.8 32.3 14.2 10.1 29.2 15.9 11.9 44.5 24.4 15.8 14.2 14.0 19.0 7.1 19.2 29.0 16.2 17.7 8.0 22.1 3.2 16.1 18.2 38.8 12.4 31.0 12.3 29.2 24.7 15.5 13.5 14.4 7.1 20.8 23.9 22.0 9.6 41.1 12.6 22.8 15.9 15.9 31.2 9.6 52.1 6.4 35.8 17.8 13.4 35.5 30.1 15.6 23.9 25.9 30.1 21.5 13.9 14.0 9.4 42.8 11.5 7.9 35.8 23.3 17.2 5.1 22.2 5.2 12.9 37.9 10.8 14.4 17.0 11.8 26.9 20.3 10.2 7.9 4.5 7.7 38.0 17.0 25.2 22.8 28.0 29.5 21.3 46.0 28.8 23.4 32.4 33.0 29.1 29.1 PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 284.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002117 Approved Approved "Endoplasmic reticulum" 1100000 "Endoplasmic reticulum" "HPA002117: AB_1855245" "unprognostic (4.60e-2)" "unprognostic (2.56e-3)" "unprognostic (2.56e-3)" "prognostic unfavourable (5.85e-6)" "unprognostic (4.97e-1)" "prognostic unfavourable (7.91e-5)" "unprognostic (5.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.29e-3)" "unprognostic (6.73e-2)" "prognostic favourable (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.72e-2)" "unprognostic (1.30e-2)" 4.4 11.6 10.0 3.0 16.2 2.3 3.9 13.0 23.6 5.8 5.3 6.1 5.4 3.0 6.4 5.8 9.1 5.4 4.8 55.5 8.2 10.1 10.9 2.7 3.6 2.4 9.4 10.8 10.8 3.0 14.2 11.4 3.3 17.9 7.1 4.2 10.8 5.2 9.4 284.3 2.6 2.8 8.3 4.6 2.7 4.1 10.3 3.8 0.0 5.5 54.9 4.6 5.3 3.7 10.7 6.7 8.7 3.2 2.2 5.4 3.5 8.7 8.5 27.0 24.6 27.6 20.1 5.5 23.7 21.8 20.5 14.6 21.0 11.0 52.2 19.7 11.5 9.8 23.4 23.9 19.3 1.2 12.2 14.9 19.4 0.7 14.8 0.7 8.6 28.4 14.1 18.0 29.7 23.3 17.8 26.4 18.9 6.6 18.3 1.2 19.3 26.5 30.9 15.8 40.1 14.0 9.7 32.0 23.5 14.0 22.3 23.7 22.5 3.2 20.9 9.5 13.2 13.9 19.7 14.4 38.4 28.6 18.4 1.5 8.0 0.4 3.2 8.7 2.5 2.8 1.0 10.7 4.3 2.4 6.7 7.0 5.4 3.0 0.8 2.2 2.3 1.0 3.8 3.5 10.0 16.2 13.0 23.6 8.2 10.1 9.4 10.8 17.9 3.8 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137712 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol 4500000 Cytosol "HPA018257: AB_10960391, HPA056484: " "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.55e-4)" "prognostic unfavourable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 14.6 7.9 29.6 22.0 28.9 9.2 8.1 34.2 61.4 9.7 20.5 11.5 7.9 26.8 19.2 11.0 36.0 12.8 19.8 62.0 29.3 32.9 20.0 2.8 9.2 18.2 22.2 29.8 9.3 8.8 1.5 16.8 8.8 21.3 20.3 19.4 14.7 13.4 36.5 24.4 16.5 31.1 34.3 21.1 11.3 20.7 71.8 14.8 9.6 19.3 11.7 13.3 26.9 15.6 8.9 12.5 16.2 4.7 14.3 20.4 8.9 47.4 66.8 4.5 0.1 4.5 9.4 58.3 29.6 10.6 30.0 36.1 70.4 50.6 5.7 23.6 21.3 38.6 22.8 46.1 31.5 16.0 17.6 20.5 32.2 3.8 10.6 8.3 34.6 4.3 10.4 31.4 15.7 57.7 5.7 0.2 33.2 37.1 28.1 8.9 7.3 23.4 22.1 7.4 22.9 32.5 18.7 12.3 10.6 21.0 17.8 26.2 14.7 13.0 69.4 20.5 11.0 61.7 32.2 32.5 29.3 20.4 52.5 15.9 12.5 16.2 4.7 1.6 15.9 2.3 12.6 8.2 15.9 14.8 8.0 8.9 6.0 9.5 0.7 14.3 0.9 12.5 20.4 8.9 29.6 28.9 34.2 51.7 29.3 32.9 22.2 29.8 21.3 14.8 PGGT1B "BGGI, GGTI" ENSG00000164219 "Protein geranylgeranyltransferase type I subunit beta" P53609 5 115204012-115262872 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030646 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA030646: AB_10602019" "unprognostic (2.73e-2)" "unprognostic (1.67e-1)" "unprognostic (3.92e-2)" "unprognostic (7.34e-2)" "unprognostic (5.57e-2)" "unprognostic (7.56e-3)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (3.25e-2)" "unprognostic (1.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (4.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.75e-1)" "unprognostic (5.93e-3)" "unprognostic (1.15e-2)" 10.5 12.4 7.3 13.3 10.1 10.9 13.9 8.8 22.1 10.8 13.8 7.7 7.9 12.3 9.2 4.6 14.9 7.3 7.0 13.5 9.5 5.9 8.2 13.7 22.2 22.2 10.2 10.0 9.6 10.1 12.0 13.4 7.8 8.2 8.4 15.1 5.7 10.6 8.4 10.2 9.9 10.4 9.5 6.9 10.4 11.0 5.1 10.5 10.2 8.8 9.9 10.1 9.6 10.5 8.0 11.5 21.8 16.7 6.7 6.3 6.4 10.1 11.1 12.6 16.3 7.4 6.2 6.2 12.6 7.4 10.5 10.8 12.0 10.9 20.7 17.1 8.8 8.0 16.6 16.5 15.8 22.8 9.2 11.9 14.4 9.6 9.9 16.3 17.6 9.3 10.2 10.3 10.8 10.5 9.6 8.9 12.0 15.8 14.3 5.4 9.4 8.6 15.7 16.9 20.9 11.0 19.2 12.4 9.4 14.9 11.4 12.0 15.3 12.2 12.0 10.8 10.2 7.4 14.6 14.8 16.5 10.9 7.8 17.0 14.9 8.3 12.8 21.8 5.0 16.6 5.6 6.8 5.7 6.3 11.5 8.0 5.4 5.0 13.1 6.7 16.7 10.3 4.9 6.4 7.3 10.1 8.8 22.1 9.5 5.9 10.2 10.0 8.2 10.5 PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129296 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved 290000000 "CAB010065: AB_628116, HPA045385: , HPA073644: , HPA073656: " "prognostic unfavourable (7.05e-8)" "prognostic unfavourable (2.69e-5)" "unprognostic (1.21e-1)" "unprognostic (8.30e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.65e-6)" "prognostic unfavourable (2.74e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "prognostic unfavourable (8.34e-4)" "unprognostic (5.66e-2)" "unprognostic (2.99e-1)" "unprognostic (8.99e-3)" "unprognostic (3.58e-1)" "unprognostic (2.90e-2)" "unprognostic (6.57e-2)" 45.0 50.9 29.2 41.3 38.4 62.2 29.9 43.8 67.9 31.9 36.6 24.2 27.5 35.5 25.7 23.3 62.1 25.6 32.4 69.4 28.6 35.0 71.8 58.5 37.5 47.6 32.1 32.7 26.8 21.2 45.7 29.0 43.7 49.9 28.3 42.8 40.0 38.2 32.0 115.5 38.7 41.9 33.9 30.1 43.7 29.7 11.3 24.9 51.8 39.1 61.1 52.4 42.2 38.0 20.9 53.7 49.2 79.0 21.0 26.3 77.0 98.9 45.9 15.4 31.0 26.6 21.6 36.6 50.7 35.3 44.6 74.9 41.6 31.2 39.7 52.5 35.0 43.1 68.0 78.8 89.5 24.2 26.8 30.7 75.7 36.1 29.2 70.3 34.3 26.9 33.3 40.4 21.5 45.5 32.0 60.7 60.8 39.1 61.4 53.2 47.5 87.4 44.5 41.3 121.5 46.5 41.4 23.0 31.7 52.5 44.8 44.0 23.5 36.9 36.6 47.8 33.0 47.7 34.9 67.5 126.1 41.7 134.5 80.0 31.2 22.7 54.6 49.2 20.8 59.9 23.2 20.9 25.0 22.6 53.7 15.8 23.0 24.4 45.7 21.0 79.0 20.9 26.3 77.0 29.2 38.4 43.8 67.9 28.6 35.0 32.1 32.7 49.9 24.9 PGK2 "PGK-2, PGKPS" ENSG00000170950 "Phosphoglycerate kinase 2" P07205 6 49785651-49787307 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "testis: 70.2" "Cell line enhanced" "Detected in some" "RT4: 1.0;U-2197: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045385, HPA073644, HPA073656" Supported "HPA045385: , HPA073644: , HPA073656: " "unprognostic (8.87e-3)" "unprognostic (5.02e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 70.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330318-74398473 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 48.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 13.1;LHCN-M2: 15.7;RH-30: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria 64000 Mitochondria "HPA056995: , HPA060948: " "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 3.0 4.0 30.6 4.9 19.8 4.0 3.2 6.3 48.6 6.1 4.5 1.3 1.0 2.3 6.1 1.9 2.1 4.7 4.8 1.6 30.1 15.1 2.5 2.1 2.7 4.0 9.7 20.4 1.7 4.4 1.4 4.5 2.1 11.7 3.8 5.1 2.9 3.2 2.5 7.1 1.7 2.6 5.6 2.6 2.5 3.4 2.3 0.3 10.0 4.1 1.3 4.0 5.2 2.6 2.4 1.7 2.5 0.6 3.0 7.5 1.1 2.0 2.9 11.5 2.1 3.5 1.5 0.3 2.7 2.1 2.4 2.6 1.0 5.4 0.2 6.8 1.8 1.0 2.3 0.5 2.3 0.8 1.2 1.6 1.6 0.9 0.4 1.9 2.6 0.8 0.5 5.4 1.0 13.1 2.1 1.4 15.7 0.3 7.4 1.6 2.3 2.6 2.3 15.0 0.1 6.2 0.4 0.5 2.3 4.4 1.0 2.0 0.2 0.3 10.9 5.3 5.0 2.1 2.8 1.9 2.8 0.2 0.5 2.6 1.2 2.5 0.6 1.1 2.1 0.6 2.8 2.4 3.5 2.3 0.5 1.8 3.3 1.9 0.7 3.0 0.3 1.7 7.5 1.1 30.6 19.8 6.3 24.4 30.1 15.1 9.7 20.4 11.7 0.3 PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378640-78425114 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved Approved "Vesicles,Cell Junctions,Intermediate filaments" "Vesicles, Cell Junctions, Intermediate filaments" "HPA022526: AB_1855271" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "prognostic unfavourable (1.37e-4)" "unprognostic (5.76e-3)" "unprognostic (3.17e-2)" "unprognostic (8.46e-3)" "prognostic favourable (7.33e-5)" "prognostic unfavourable (9.94e-4)" "prognostic unfavourable (1.16e-5)" "unprognostic (9.94e-2)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" 16.4 11.6 14.5 20.8 20.3 41.4 28.2 17.6 17.4 14.4 13.1 18.4 13.2 13.7 17.3 13.2 14.5 16.9 17.2 14.0 15.7 16.1 14.3 8.0 25.5 19.1 21.6 17.0 18.3 14.0 16.0 13.3 24.0 15.3 13.9 10.2 12.9 13.1 16.8 13.8 11.9 15.1 13.4 18.0 22.6 12.6 13.9 18.8 17.7 18.6 7.8 14.3 16.9 32.3 8.0 14.0 26.0 12.6 6.7 11.3 8.4 13.1 11.6 11.3 8.5 10.0 16.0 13.4 12.4 11.9 13.3 14.7 10.8 10.4 13.6 7.5 7.0 10.2 13.4 8.4 10.5 20.4 15.2 14.9 13.8 10.8 9.8 11.2 12.1 16.3 11.1 9.6 8.7 25.4 17.3 9.5 9.0 7.2 25.3 10.1 11.8 11.2 13.3 20.3 11.6 13.0 12.1 15.0 22.8 10.6 11.7 11.3 12.3 13.6 15.9 17.3 12.0 9.2 10.4 10.5 6.2 10.3 13.1 12.6 12.8 1.5 12.6 13.2 8.4 10.4 9.8 7.8 8.8 8.8 14.0 8.0 11.3 8.1 26.0 6.7 4.6 6.6 10.4 8.4 14.5 20.3 17.6 17.4 15.7 16.1 21.6 17.0 15.3 18.8 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.7 3.1 5.3 1.4 0.3 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.5 1.2 0.2 0.8 0.8 2.1 0.8 2.9 0.7 0.8 1.5 3.2 3.3 2.2 1.6 0.7 0.3 2.2 3.9 0.1 1.3 2.2 5.5 1.0 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.1 0.1 1.1 1.9 0.8 0.5 1.7 4.4 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favourable (7.90e-4)" "prognostic unfavourable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favourable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favourable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.5 8.9 7.5 9.2 7.1 5.7 16.9 9.5 14.3 13.0 14.9 7.7 6.8 11.7 11.3 9.8 13.0 7.8 12.1 10.5 6.3 21.7 6.4 14.8 21.6 10.9 9.9 9.2 7.7 6.6 12.5 5.9 13.2 8.7 6.8 9.4 31.2 11.7 14.6 10.3 10.4 15.8 11.7 15.6 14.9 15.3 10.1 7.0 7.7 21.5 9.1 16.9 8.6 7.8 8.0 8.9 10.0 8.7 13.8 7.5 8.0 15.9 19.4 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" "Plasma membrane" "CAB030649: , HPA076857: " "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavourable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 17.2 23.0 13.8 10.7 21.2 22.8 9.5 16.8 33.8 12.0 9.1 16.8 9.5 10.9 12.8 15.5 18.3 8.9 16.1 15.2 14.5 17.9 14.7 17.1 15.0 11.0 15.9 15.7 10.6 9.5 23.2 15.5 19.9 30.7 10.3 10.2 23.8 10.1 12.7 11.3 15.3 9.9 15.0 9.9 14.4 8.8 14.9 7.5 8.2 12.0 8.8 11.8 13.6 11.2 4.1 3.7 1.1 3.4 1.9 4.0 1.6 12.0 9.1 7.5 13.4 16.2 11.7 6.1 12.1 26.7 19.1 20.3 8.2 12.0 4.4 7.2 15.3 11.7 8.4 24.1 15.9 5.3 7.1 3.9 6.4 7.4 15.5 3.5 5.6 12.3 20.6 20.0 35.6 9.7 6.1 7.2 13.2 6.1 7.6 2.7 4.8 8.6 3.6 7.8 4.3 13.1 11.3 2.5 8.4 10.2 2.6 15.0 7.1 5.6 10.7 9.1 6.8 10.8 9.3 6.4 7.5 7.2 16.9 2.1 2.9 0.0 3.4 0.0 4.0 2.3 2.8 4.1 1.7 3.4 3.7 1.9 1.4 2.6 1.1 1.9 1.6 1.7 3.1 1.6 13.8 21.2 16.8 33.8 14.5 17.9 15.9 15.7 30.7 7.5 PI4K2B "FLJ11105, PI4KIIB, PIK42B" ENSG00000038210 "Phosphatidylinositol 4-kinase type 2 beta" Q8TCG2 4 25233975-25279092 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 49.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA004099 Approved Supported Cytosol Cytosol "HPA004099: AB_1855353" "unprognostic (1.02e-1)" "unprognostic (6.34e-3)" "prognostic favourable (9.64e-5)" "unprognostic (2.75e-2)" "unprognostic (1.98e-2)" "unprognostic (2.68e-2)" "unprognostic (7.54e-2)" "unprognostic (7.75e-2)" "unprognostic (5.06e-1)" "unprognostic (6.39e-3)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (9.07e-2)" "unprognostic (9.61e-2)" "unprognostic (2.39e-2)" "unprognostic (2.02e-2)" "unprognostic (4.47e-2)" 9.2 7.1 3.4 13.6 2.9 3.9 8.0 3.2 2.3 8.7 48.4 4.1 11.3 19.4 7.4 8.0 13.5 4.9 9.5 4.2 3.1 2.7 12.9 38.6 14.3 9.4 3.5 2.3 6.9 10.5 4.2 5.7 7.7 2.9 6.4 9.8 3.3 22.6 12.0 4.4 8.6 49.3 6.9 4.5 13.8 11.3 8.0 2.7 18.6 16.2 12.9 14.1 7.8 10.3 1.4 1.8 1.5 1.0 0.4 4.1 0.4 11.3 2.0 4.8 5.1 6.5 12.1 11.8 17.1 16.1 15.0 19.2 3.6 12.2 29.4 3.9 12.9 4.7 10.9 8.6 14.9 8.9 3.8 9.4 5.1 9.1 6.2 18.9 7.3 8.1 7.8 5.6 5.9 10.1 6.2 24.7 14.5 4.4 18.2 16.9 8.4 4.6 11.0 18.9 17.1 13.2 8.1 10.1 2.2 8.7 6.9 3.5 9.8 11.0 10.4 10.7 2.7 6.5 11.0 28.4 13.5 22.4 12.5 16.1 10.8 1.5 0.4 0.0 1.3 1.0 0.9 1.4 1.5 1.2 0.3 1.0 1.4 1.3 0.2 0.4 0.9 1.8 4.1 0.4 3.4 2.9 3.2 2.3 3.1 2.7 3.5 2.3 2.9 2.7 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0" "Cell line enhanced" "Detected in all" "K-562: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" 18000 Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: " "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favourable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favourable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 7.7 9.2 28.8 10.5 34.2 12.5 6.5 14.1 48.0 9.7 8.8 10.1 4.9 9.1 9.7 6.1 8.3 8.4 8.0 8.5 30.4 19.2 9.0 12.6 9.0 11.2 19.0 25.9 10.2 8.6 25.6 12.5 10.4 19.3 9.8 8.9 10.8 6.8 10.6 7.1 6.6 10.0 13.2 6.8 10.2 9.9 13.1 8.2 17.9 9.9 2.9 10.2 8.4 4.8 5.0 12.5 7.6 5.5 9.1 7.7 2.9 9.7 8.2 7.3 10.9 20.8 12.6 10.4 8.9 13.5 13.1 12.8 6.4 4.2 18.4 5.3 17.8 8.6 13.8 8.5 8.0 15.6 21.2 18.9 11.2 7.3 10.4 18.7 15.2 11.2 5.4 11.1 6.2 10.6 51.5 15.6 10.1 13.5 16.3 6.4 5.7 8.5 16.4 15.9 3.4 7.3 15.6 17.9 13.1 11.6 13.5 9.2 11.4 8.6 10.7 23.9 12.4 8.8 7.4 12.0 12.2 14.6 15.8 13.5 9.9 3.1 5.5 7.3 5.1 5.4 4.9 4.6 5.6 6.1 3.6 5.0 5.7 7.7 7.6 9.1 4.6 12.5 5.8 2.9 28.8 34.2 14.1 48.0 30.4 19.2 19.0 25.9 19.3 8.2 PI4KB "PI4K-BETA, pi4K92, PIK4CB" ENSG00000143393 "Phosphatidylinositol 4-kinase beta" Q9UBF8 1 151291797-151327715 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006280, HPA006281, CAB022071" Approved Supported "Golgi apparatus" "Golgi apparatus" "CAB022071: , HPA006280: AB_1079613, HPA006281: AB_1079614" "unprognostic (1.17e-1)" "unprognostic (1.57e-1)" "unprognostic (5.42e-3)" "unprognostic (5.23e-3)" "unprognostic (7.32e-2)" "unprognostic (1.36e-2)" "prognostic unfavourable (2.97e-4)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (1.58e-1)" "prognostic favourable (1.25e-5)" "unprognostic (8.51e-2)" "prognostic unfavourable (3.23e-4)" "unprognostic (2.53e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (6.78e-4)" "unprognostic (7.08e-2)" 25.5 22.2 29.8 21.6 32.3 41.6 27.3 42.6 47.2 30.8 27.1 44.8 26.6 21.8 38.6 35.8 25.6 33.0 25.1 23.8 26.3 22.5 25.6 19.3 27.2 26.2 38.7 28.8 38.6 22.6 41.8 35.5 24.2 29.6 32.2 28.1 28.8 27.1 29.9 36.2 36.9 25.3 39.8 22.7 34.7 23.7 33.1 34.0 26.2 41.2 24.6 28.7 27.1 30.1 17.1 19.7 27.9 20.4 14.7 20.3 17.1 19.3 16.2 14.1 22.1 39.2 29.0 12.0 20.6 36.0 27.0 22.5 20.7 17.6 18.3 23.8 31.5 18.3 23.4 21.2 20.9 24.9 20.8 13.1 19.2 10.6 27.5 15.0 25.3 30.3 25.9 29.9 21.4 26.0 22.3 27.9 22.9 36.0 16.0 12.2 11.3 24.7 14.3 11.9 21.5 18.7 24.6 17.1 14.7 14.3 29.2 18.5 24.6 28.7 20.2 19.4 15.3 15.4 21.9 29.7 19.3 35.8 22.1 15.8 33.5 25.2 17.5 27.9 15.6 20.4 17.4 17.1 16.1 20.3 19.7 15.1 13.6 12.5 17.2 14.7 19.6 11.4 15.9 17.1 29.8 32.3 42.6 47.2 26.3 22.5 38.7 28.8 29.6 34.0 PIAS4 "FLJ12419, Piasg, PIASY, ZMIZ6" ENSG00000105229 "Protein inhibitor of activated STAT 4" Q8N2W9 19 4007646-4039386 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010598 Enhanced Approved Nucleoplasm Nucleoplasm "HPA010598: AB_1079616" "unprognostic (1.23e-1)" "unprognostic (8.94e-3)" "unprognostic (3.50e-2)" "prognostic favourable (1.18e-5)" "unprognostic (2.45e-1)" "unprognostic (4.77e-3)" "unprognostic (4.01e-3)" "unprognostic (9.79e-2)" "unprognostic (6.89e-2)" "unprognostic (6.22e-2)" "prognostic favourable (7.04e-4)" "unprognostic (1.33e-2)" "unprognostic (5.98e-2)" "unprognostic (4.52e-3)" "unprognostic (5.76e-2)" "unprognostic (1.25e-1)" "unprognostic (4.67e-3)" 11.0 9.2 12.4 11.1 16.8 8.6 7.6 22.5 15.7 8.8 11.9 16.7 8.1 13.0 9.5 9.2 9.1 8.4 9.7 6.9 9.7 7.1 7.3 12.4 7.8 10.2 18.2 9.3 11.2 16.0 7.1 9.3 12.9 12.6 9.9 5.4 6.5 14.7 8.7 15.2 12.2 11.2 8.0 12.3 12.0 13.9 38.1 15.9 11.0 6.6 6.3 8.3 8.8 9.8 17.9 11.8 20.2 19.1 16.3 17.3 11.3 10.5 7.6 7.1 6.8 3.5 3.2 11.3 6.4 3.6 6.8 6.2 11.8 4.9 8.0 5.9 3.4 11.1 7.3 5.1 2.9 12.9 11.4 5.7 5.4 9.1 7.2 8.3 10.1 3.7 5.7 6.1 3.8 8.0 10.7 11.1 3.3 10.8 15.1 9.8 15.7 7.0 13.5 7.3 10.4 4.4 5.9 13.0 14.5 9.2 9.0 7.0 8.3 7.7 5.9 6.8 9.8 14.1 10.0 20.8 15.5 10.2 5.7 10.3 8.3 10.5 14.9 20.2 17.3 16.0 12.2 17.9 12.6 15.9 11.8 15.9 11.1 12.5 16.6 16.3 19.1 11.8 13.4 11.3 12.4 16.8 22.5 15.7 9.7 7.1 18.2 9.3 12.6 15.9 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319451-15335580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved "HPA001174: " "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavourable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 6.9 6.1 6.8 5.0 8.6 16.1 7.0 7.6 10.0 6.0 6.8 9.6 5.8 3.5 6.2 7.5 9.9 5.6 7.8 6.2 8.0 5.4 7.5 11.0 14.4 5.9 9.6 6.4 7.0 9.9 8.5 5.2 10.8 16.7 5.9 7.5 7.0 11.5 9.1 4.2 10.9 4.8 5.2 10.2 5.7 7.2 5.3 9.4 4.7 8.6 8.5 8.7 11.6 6.6 2.9 3.9 16.7 7.6 1.5 4.4 2.4 12.4 7.7 8.0 4.1 2.4 2.4 6.6 3.2 5.2 7.2 6.9 8.4 5.5 5.8 2.7 2.6 4.9 13.3 10.8 11.8 5.2 9.1 5.0 9.5 4.9 4.1 7.1 2.6 3.4 7.3 9.3 14.8 4.5 5.4 6.3 4.3 7.8 7.9 2.6 4.2 8.6 2.8 11.5 9.2 5.1 8.4 5.6 8.6 6.5 5.9 12.6 6.0 6.2 3.8 5.4 2.2 11.9 6.5 4.8 6.1 9.0 8.3 5.0 6.8 16.7 3.6 3.9 2.7 6.0 3.8 2.9 4.4 2.7 3.9 2.2 4.0 3.1 5.2 1.5 7.6 2.5 3.8 2.4 6.8 8.6 7.6 10.0 8.0 5.4 9.6 6.4 16.7 9.4 PIGC ENSG00000135845 "Phosphatidylinositol glycan anchor biosynthesis class C" Q92535 1 172370189-172444086 "Enzymes, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036663 Uncertain "HPA036663: AB_10669912" "unprognostic (3.35e-1)" "unprognostic (3.01e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (2.65e-1)" "unprognostic (3.72e-3)" "prognostic unfavourable (4.49e-4)" "unprognostic (7.25e-2)" "unprognostic (2.20e-2)" "unprognostic (4.69e-2)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (1.43e-8)" "unprognostic (1.09e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" "unprognostic (1.90e-1)" 13.8 13.1 10.0 9.0 11.2 14.4 13.9 11.3 12.3 14.4 12.3 9.0 20.9 9.3 14.5 26.1 11.6 15.1 12.1 14.1 8.4 10.2 11.5 12.5 9.0 13.1 12.0 6.6 14.9 16.4 9.2 11.6 14.4 9.6 17.1 12.3 13.2 12.7 15.7 14.8 21.3 15.8 13.5 9.9 12.4 10.5 13.5 9.8 14.2 15.8 10.8 12.3 11.0 10.8 18.9 12.5 27.4 14.5 25.1 33.8 19.2 19.1 16.6 22.6 15.3 17.1 15.6 16.8 12.5 14.1 21.7 19.0 14.8 28.2 10.3 18.5 14.9 20.8 14.6 18.2 17.5 22.8 17.0 12.6 15.8 18.5 19.0 25.8 16.6 23.3 21.9 15.5 17.1 13.7 19.1 19.8 17.4 9.8 19.6 23.2 23.2 23.2 16.2 18.3 18.4 33.3 14.2 11.8 22.5 18.1 21.5 28.2 19.0 18.5 12.5 13.9 23.3 16.9 13.3 13.3 18.8 16.2 9.9 17.0 26.2 27.4 14.5 27.3 19.4 13.5 16.4 18.9 22.7 20.4 12.5 16.7 33.8 24.2 9.5 25.1 14.1 12.4 19.8 19.2 10.0 11.2 11.3 12.3 8.4 10.2 12.0 6.6 9.6 9.8 PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600287 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Autism spectrum disorder, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved "HPA031624: AB_10601046" "unprognostic (1.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (3.47e-2)" "unprognostic (8.25e-3)" "unprognostic (8.69e-3)" "unprognostic (3.26e-3)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (6.17e-3)" "unprognostic (1.39e-1)" "prognostic favourable (2.68e-7)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (7.00e-2)" "unprognostic (3.73e-1)" 9.7 22.7 15.1 8.8 15.9 18.6 18.5 21.5 18.8 21.8 10.1 11.9 11.5 10.3 10.6 30.6 10.2 9.2 15.6 12.5 14.0 17.2 28.0 18.3 9.1 11.0 19.5 11.3 16.7 21.4 56.0 9.4 17.9 17.8 24.1 9.8 21.0 19.9 17.2 19.5 12.7 12.7 13.1 19.2 11.1 12.2 23.6 14.5 13.5 31.5 7.4 10.5 10.8 10.7 31.8 14.4 24.4 20.4 23.5 29.9 16.8 13.9 9.2 8.8 18.3 19.7 7.6 7.5 7.7 9.5 10.9 10.7 14.7 4.9 9.7 7.8 5.3 10.3 15.5 11.1 12.2 14.4 20.6 10.0 7.8 15.0 15.6 7.4 12.2 11.0 14.3 8.3 12.7 6.9 22.5 6.9 7.9 12.2 10.7 12.2 1.6 24.9 3.6 8.9 5.7 11.6 11.7 11.1 13.3 5.9 11.4 18.9 13.1 7.4 3.5 11.1 14.0 14.3 9.2 13.2 8.5 6.6 8.6 15.7 15.2 17.9 12.6 24.4 23.1 16.6 29.9 29.6 24.4 21.5 12.3 31.8 25.7 24.0 6.0 23.5 20.4 14.4 22.3 16.8 15.1 15.9 21.5 18.8 14.0 17.2 19.5 11.3 17.8 14.5 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37059170-37073170 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 20.0 30.3 12.3 7.9 13.4 4.2 18.0 6.9 14.3 13.1 13.8 15.6 23.1 9.9 11.7 60.6 12.5 13.9 15.2 27.8 12.3 15.2 19.0 27.4 14.7 9.9 16.1 9.8 15.0 45.4 23.9 28.9 16.2 17.9 21.3 14.3 16.6 22.2 17.4 25.0 7.0 12.8 24.0 24.8 10.1 14.8 19.3 8.4 16.3 20.3 17.3 9.9 17.2 9.2 18.2 16.7 1.7 11.1 8.7 19.3 8.7 9.5 4.5 9.6 5.8 17.3 11.4 6.4 7.7 14.3 7.0 7.9 6.0 20.2 13.1 17.3 11.6 7.7 7.9 8.8 7.4 13.6 13.8 29.8 5.7 8.3 10.5 8.8 6.5 10.3 16.6 12.6 15.8 12.0 17.7 23.5 15.4 6.3 11.7 9.7 7.3 11.1 11.4 4.9 13.8 17.6 5.3 19.7 11.8 21.8 16.4 29.2 14.0 19.3 6.2 5.2 2.5 6.0 7.0 31.3 34.0 15.0 15.0 11.3 17.0 0.2 7.1 1.7 11.3 10.4 14.0 18.2 14.5 12.1 11.1 15.3 19.3 16.7 1.0 8.7 11.1 16.7 10.7 8.7 12.3 13.4 6.9 14.3 12.3 15.2 16.1 9.8 17.9 8.4 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584136 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: " "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favourable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.9 15.7 12.8 8.7 13.9 48.4 8.4 12.8 20.6 8.4 9.7 11.4 16.7 15.4 10.9 23.3 7.2 10.0 13.6 7.4 10.5 11.1 18.9 12.5 13.0 6.2 9.1 13.2 10.4 29.3 18.1 15.3 8.4 9.4 11.2 4.1 15.4 15.5 17.6 12.4 12.8 8.1 5.5 7.2 10.3 13.6 15.3 8.2 11.8 18.4 4.2 7.9 9.8 6.7 5.6 10.5 5.9 6.0 5.5 5.3 3.9 8.5 12.9 4.6 6.4 3.0 1.8 8.7 9.0 3.5 3.9 4.2 9.0 8.0 4.5 11.8 2.0 13.7 2.1 4.0 0.8 13.0 18.9 6.9 14.0 6.4 5.8 6.0 6.5 3.2 6.0 6.5 1.3 3.6 15.4 2.6 1.3 11.1 11.1 6.9 6.2 13.3 21.5 3.8 10.4 3.5 3.4 8.3 13.2 10.2 4.7 6.5 10.7 4.1 8.7 6.6 8.4 7.4 6.2 9.9 2.9 3.6 2.2 3.2 6.4 1.2 4.8 3.0 5.3 5.6 4.6 4.4 4.6 5.1 4.9 5.6 5.1 3.1 5.9 5.5 6.0 10.5 4.2 3.9 12.8 13.9 12.8 20.6 10.5 11.1 9.1 13.2 9.4 8.2 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Enzymes, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm Nucleoplasm "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favourable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.3 16.8 17.6 17.2 26.3 9.2 20.0 22.6 17.2 22.1 17.2 13.9 22.2 15.6 20.3 19.2 16.8 18.2 20.2 16.3 14.5 11.6 25.7 16.3 22.2 11.3 17.6 16.1 17.6 14.2 62.9 23.0 23.5 28.5 18.7 14.3 15.2 15.6 27.5 15.4 13.1 17.9 19.5 31.8 17.5 18.3 19.4 18.0 11.4 32.2 9.3 11.5 23.1 20.5 4.4 5.2 6.0 7.2 4.2 4.8 1.6 22.8 10.5 17.6 10.9 12.7 13.0 15.7 14.5 15.7 10.6 14.9 25.4 2.6 6.7 7.2 12.4 15.2 14.0 11.0 19.0 5.7 12.1 4.1 12.7 9.9 13.9 5.2 6.7 10.1 7.8 10.5 20.6 25.3 9.8 6.5 8.2 7.1 2.8 3.2 10.0 8.1 2.9 18.3 4.6 13.2 20.3 10.4 9.2 22.0 9.5 10.2 5.6 5.3 31.5 8.6 12.4 22.2 8.8 2.6 5.8 5.5 10.2 4.9 9.9 4.1 4.1 2.9 4.6 2.5 3.0 3.6 3.7 3.6 5.2 4.4 4.8 2.8 6.0 4.2 7.2 3.7 2.3 1.6 17.6 26.3 22.6 17.2 14.5 11.6 17.6 16.1 28.5 18.0 PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494724 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 31.9;RT4: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA030515: AB_10670043, HPA050360: " "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.45e-1)" "unprognostic (2.19e-3)" "prognostic unfavourable (5.42e-4)" "unprognostic (3.35e-3)" "unprognostic (3.57e-3)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "prognostic favourable (1.16e-4)" 12.9 4.5 11.0 16.0 19.3 5.3 11.0 9.1 17.5 7.4 17.0 36.0 9.6 15.5 10.5 5.8 14.6 7.7 14.7 10.7 14.4 9.1 7.6 5.8 18.0 23.9 24.2 11.2 3.9 6.1 4.7 4.3 20.4 14.5 7.3 14.5 6.3 8.0 14.1 20.0 22.6 15.7 11.2 16.2 14.2 20.7 2.4 23.0 31.8 9.8 8.1 23.1 13.1 11.8 7.4 0.3 0.5 0.2 1.6 2.0 0.4 3.2 6.5 5.8 5.3 3.4 0.3 31.9 0.4 1.3 1.3 0.9 3.8 8.5 5.5 1.2 0.7 8.1 3.4 2.3 0.5 3.3 0.9 0.1 12.9 1.4 0.2 1.9 4.2 0.4 2.4 0.3 0.2 8.5 2.0 3.7 0.1 7.2 6.6 5.5 5.3 4.1 7.2 1.4 1.0 1.6 33.3 6.4 3.5 11.5 16.2 3.7 7.2 1.0 0.3 0.2 2.1 0.6 0.1 4.0 1.1 7.2 0.2 2.9 0.8 0.1 0.2 0.0 1.2 0.0 1.0 2.9 1.3 0.8 0.3 7.4 0.7 0.6 0.5 1.6 0.0 0.1 2.0 0.4 11.0 19.3 9.1 17.5 14.4 9.1 24.2 11.2 14.5 23.0 PIK3C2G ENSG00000139144 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma" O75747 12 18247614-18648416 "Enzymes, Plasma proteins, Predicted intracellular proteins" Chemotaxis "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 54.2;epididymis: 30.7;seminal vesicle: 46.0" "Group enriched" "Detected in some" 5 "BEWO: 2.9;HaCaT: 4.6;hTERT-HME1: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "unprognostic (1.29e-1)" "unprognostic (1.61e-1)" "unprognostic (6.21e-2)" "unprognostic (1.47e-2)" "unprognostic (9.46e-2)" "unprognostic (8.27e-2)" "unprognostic (2.85e-1)" "unprognostic (6.52e-2)" "unprognostic (1.81e-3)" "prognostic unfavourable (3.50e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-1)" "unprognostic (1.98e-1)" "unprognostic (2.37e-2)" 0.3 0.6 0.2 0.1 0.2 0.0 6.7 0.2 0.3 0.6 0.3 0.1 54.2 0.0 0.3 30.7 4.2 0.6 6.0 0.2 0.3 0.2 9.6 8.8 0.3 0.1 0.3 0.1 0.3 1.2 8.1 0.4 1.2 0.1 2.4 0.0 0.1 13.1 46.0 0.2 7.0 2.2 0.2 0.3 0.2 15.1 2.1 0.1 0.1 0.5 1.6 0.5 0.9 0.9 0.1 0.1 0.4 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 8.5 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.3 0.2 0.3 0.1 0.1 0.1 PIK3C3 Vps34 ENSG00000078142 "Phosphatidylinositol 3-kinase catalytic subunit type 3" Q8NEB9 18 41955206-42087830 "Enzymes, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040718 Approved "HPA040718: AB_10793862" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" "unprognostic (3.55e-3)" "unprognostic (6.15e-2)" "unprognostic (3.61e-2)" "unprognostic (6.00e-3)" "unprognostic (1.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.86e-2)" "unprognostic (6.41e-2)" "prognostic favourable (4.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-3)" 19.3 24.1 24.0 14.8 28.3 18.5 21.8 48.2 29.6 18.9 15.3 18.2 17.9 11.4 21.1 23.1 18.8 16.8 16.2 17.0 22.9 12.8 21.9 18.2 16.7 16.7 22.6 22.1 23.9 15.1 23.1 33.7 22.2 30.7 17.7 18.3 12.3 21.2 17.7 21.2 20.7 14.6 18.4 27.4 18.5 16.2 22.2 28.0 24.0 20.3 13.0 20.0 18.0 17.8 10.8 9.4 19.2 10.7 11.1 15.7 7.4 7.4 5.2 13.4 10.2 15.7 17.0 8.2 14.9 19.0 12.0 16.3 2.5 3.8 4.6 8.5 15.0 12.4 10.4 8.3 16.7 7.5 7.3 9.7 8.1 10.2 13.1 14.1 10.6 18.5 12.6 11.2 14.7 12.3 9.3 5.9 16.5 2.4 6.2 9.2 9.9 3.9 38.1 10.0 12.0 13.9 8.2 11.8 13.7 4.7 3.6 10.4 5.2 11.8 15.9 16.3 4.7 3.6 6.8 16.1 18.8 5.3 13.5 19.4 8.6 14.5 9.4 19.2 9.3 10.3 10.3 10.8 9.4 11.4 9.4 9.2 12.3 9.1 18.3 11.1 10.7 5.6 15.7 7.4 24.0 28.3 48.2 29.6 22.9 12.8 22.6 22.1 30.7 28.0 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Approved Cytosol Cytosol "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 20.1 12.3 13.7 11.5 13.4 25.7 22.4 17.1 24.5 12.9 14.0 5.2 5.7 6.5 15.3 7.9 11.6 11.1 13.2 14.2 18.4 9.7 11.7 10.8 13.2 13.8 9.8 15.7 15.4 9.2 24.7 11.6 16.5 16.3 10.7 8.9 7.2 10.9 10.9 15.2 12.0 10.5 12.8 14.4 16.2 10.6 9.3 9.8 29.6 11.0 7.3 13.9 15.1 15.7 6.2 2.6 7.8 3.8 2.4 5.0 1.1 14.4 4.9 7.9 7.3 18.7 21.8 5.7 9.2 12.5 9.1 14.4 4.2 10.7 13.2 15.8 11.0 5.9 6.4 8.0 13.2 22.0 5.7 18.1 5.3 3.7 8.9 10.1 10.3 13.7 8.5 10.0 11.5 13.0 9.0 14.7 13.0 5.7 7.7 9.1 6.2 6.7 11.8 8.0 15.8 7.2 8.8 4.4 7.6 10.0 8.9 12.0 14.9 8.7 13.8 8.6 5.6 13.5 9.2 7.1 10.1 23.7 7.7 7.6 5.0 2.1 3.8 1.6 5.0 2.9 3.9 5.8 4.2 2.8 2.2 6.2 4.6 3.8 7.8 2.4 3.0 2.6 4.1 1.1 13.7 13.4 17.1 24.5 18.4 9.7 9.8 15.7 16.3 9.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652699-138834938 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 41.2;HMC-1: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: " "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavourable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 12.5 9.9 10.6 9.7 20.6 17.4 11.5 29.9 25.0 12.4 14.6 11.9 11.7 13.7 9.6 6.9 15.2 10.9 8.7 12.7 12.2 14.2 22.6 9.3 9.5 9.1 11.9 15.2 8.8 20.3 20.2 10.9 18.1 24.1 13.4 15.7 12.2 14.9 15.9 33.4 19.6 16.4 8.3 12.5 9.9 11.0 6.4 10.7 14.4 37.4 7.1 11.9 13.4 11.0 4.6 9.1 11.3 7.8 1.3 6.5 2.6 22.6 9.8 4.2 3.5 3.9 5.2 28.7 5.3 5.1 5.4 5.8 10.5 8.6 9.1 14.5 5.2 9.7 5.5 8.4 9.7 11.6 6.2 41.2 6.7 6.3 4.0 10.0 65.3 4.4 6.5 3.8 7.7 8.1 15.7 6.8 6.7 10.3 5.8 7.0 6.0 9.2 4.2 4.4 6.5 8.3 12.5 3.7 2.7 14.7 6.4 18.9 16.0 23.9 8.5 3.5 4.4 7.5 7.4 11.5 7.5 8.3 8.5 9.7 4.8 7.0 7.8 11.3 4.0 4.5 2.7 4.6 5.2 3.0 9.1 4.1 6.5 4.4 10.0 1.3 4.3 1.4 2.2 2.6 10.6 20.6 29.9 25.0 12.2 14.2 11.9 15.2 24.1 10.7 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651732-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.0;bone marrow: 32.8;lymphoid tissue: 40.3" "Cell line enhanced" "Detected in many" "HDLM-2: 50.5;NB-4: 21.8;REH: 22.7;THP-1: 22.0;U-937: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: " "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 4.5 2.1 3.4 34.8 7.1 32.8 2.9 3.3 4.3 3.2 3.3 5.5 0.7 3.1 3.7 3.4 3.5 4.0 6.5 2.9 4.2 3.1 4.6 3.3 8.2 40.3 7.4 1.8 5.3 2.2 2.3 2.2 3.3 4.6 3.2 2.1 3.1 11.2 1.8 0.9 2.0 11.4 2.9 5.3 35.5 3.3 3.0 5.7 23.5 4.1 2.3 36.0 5.8 3.6 8.4 14.5 35.0 15.0 14.5 13.7 16.6 2.6 1.7 0.1 0.5 0.4 0.4 0.2 4.1 8.4 9.0 7.4 0.1 1.1 7.1 1.7 3.3 0.8 0.7 3.7 5.7 50.5 0.1 0.8 0.4 3.0 1.8 18.4 6.4 1.5 1.5 10.1 3.4 1.3 2.6 0.0 5.1 0.2 1.7 21.8 0.7 0.5 22.7 4.5 0.2 3.8 0.0 0.5 0.5 0.9 1.7 4.0 0.2 22.0 3.3 2.7 2.8 0.0 3.8 1.6 1.6 10.0 5.8 26.3 1.5 9.6 11.8 21.1 12.9 13.1 13.7 7.8 9.8 11.8 12.5 8.4 12.9 13.4 35.0 14.5 15.0 14.5 7.4 16.6 3.4 7.1 3.3 4.3 4.2 3.1 7.4 1.8 4.6 5.7 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106907145 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 24.5;bone marrow: 27.8;lymphoid tissue: 40.8" "Cell line enhanced" "Detected in some" "Daudi: 12.2;HMC-1: 15.2;Karpas-707: 12.6;MOLT-4: 23.0;U-266/70: 30.9;U-937: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA069976: " "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 5.0 1.8 2.2 16.0 3.1 27.8 2.3 0.8 1.7 1.7 4.1 2.7 0.0 2.8 1.7 2.0 2.0 1.8 3.5 1.7 1.7 1.5 1.9 1.5 4.3 13.1 3.0 1.0 1.7 1.5 0.6 1.4 2.0 2.5 2.2 2.6 1.9 3.1 0.5 1.1 1.3 6.1 1.9 6.4 17.4 2.5 7.6 3.0 40.8 2.3 0.9 21.2 4.1 1.5 6.2 5.6 14.2 24.5 5.3 5.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 11.9 15.2 0.0 0.0 0.0 0.0 4.7 8.5 12.6 0.0 0.0 23.0 4.6 0.0 0.0 6.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 1.2 0.0 0.1 0.0 0.0 30.9 0.0 11.5 0.0 21.8 2.9 4.6 3.4 14.2 5.6 10.6 5.1 4.7 2.6 4.2 5.6 6.2 2.8 3.8 13.9 5.3 24.5 4.9 2.6 3.6 2.2 3.1 0.8 1.7 1.7 1.5 3.0 1.0 2.5 3.0 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678935-130746829 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: " "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favourable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 15.5 16.2 11.6 11.6 15.9 10.6 14.9 14.7 17.2 16.5 13.1 14.9 9.5 10.3 18.8 12.0 12.9 15.6 12.0 12.2 9.7 10.0 14.9 28.2 13.7 12.4 12.0 11.4 17.8 12.0 40.7 20.6 14.4 17.3 14.1 11.6 14.1 14.0 15.4 14.8 16.0 13.4 14.6 12.1 18.5 13.3 14.9 11.8 29.7 18.1 10.2 13.6 16.5 13.9 8.4 9.6 12.0 8.5 11.5 13.7 7.0 14.1 9.0 13.2 9.5 19.6 15.6 9.2 10.5 12.7 14.6 16.9 11.6 12.1 16.7 13.3 10.6 20.2 21.7 16.4 23.0 10.0 8.0 13.6 10.3 8.0 9.0 20.6 6.8 10.8 11.8 15.5 9.9 13.4 15.7 8.5 12.8 12.4 16.8 6.3 16.6 8.8 11.8 15.4 15.0 9.6 11.6 12.2 8.9 15.1 9.6 10.6 13.2 9.1 10.6 11.2 9.8 12.6 8.4 9.9 9.0 22.0 12.3 7.9 10.4 12.0 7.2 9.2 9.4 8.4 13.7 8.4 8.6 6.9 9.6 5.7 10.1 9.0 6.0 11.5 8.5 3.4 9.3 7.0 11.6 15.9 14.7 17.2 9.7 10.0 12.0 11.4 17.3 11.8 PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266267-208358751 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042558, HPA042604" Uncertain Supported Vesicles Vesicles "HPA042558: , HPA042604: AB_10796580" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.88e-1)" "unprognostic (3.03e-1)" "unprognostic (2.04e-2)" "prognostic favourable (6.81e-4)" "unprognostic (6.82e-3)" "unprognostic (6.45e-2)" "unprognostic (1.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" 15.9 13.5 17.7 21.1 21.9 36.1 24.9 25.6 23.1 14.8 12.1 14.0 16.6 9.1 14.7 18.3 11.2 12.6 11.1 12.5 19.4 14.3 16.2 15.2 16.5 23.1 14.4 15.3 15.6 31.5 21.5 17.0 14.1 20.6 17.7 11.5 13.8 13.7 19.7 13.6 12.9 15.3 13.5 24.4 21.7 12.1 19.3 15.8 23.5 18.2 7.8 22.6 12.4 14.0 7.5 2.1 1.4 1.2 5.6 2.6 0.5 5.0 5.0 12.0 9.3 12.1 14.5 5.6 6.2 12.6 7.3 10.0 7.2 4.2 5.8 6.5 10.6 5.2 10.4 6.9 12.5 4.9 6.6 20.8 9.9 6.4 9.2 18.3 18.8 10.8 7.6 8.5 16.0 11.8 14.0 10.5 9.1 2.1 16.6 13.8 9.9 3.8 6.2 9.3 7.9 9.4 7.3 3.8 9.1 6.8 4.4 12.3 2.8 19.8 13.5 9.2 6.1 6.1 5.7 7.4 8.7 12.4 7.3 16.0 9.0 1.4 1.0 0.7 1.7 0.8 1.1 7.5 2.3 2.6 0.9 5.4 1.8 2.1 1.4 5.6 1.2 2.1 1.5 0.5 17.7 21.9 25.6 23.1 19.4 14.3 14.4 15.3 20.6 15.8 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 34.8;HMC-1: 64.9;U-698: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.2 2.0 1.1 4.6 2.4 23.5 1.0 3.3 2.2 3.6 4.5 4.2 6.0 1.7 1.2 3.5 2.0 3.2 2.0 27.5 1.3 34.8 1.3 5.8 4.7 0.6 64.9 8.3 4.0 2.0 1.3 0.6 29.9 9.8 0.3 0.7 1.9 3.1 3.7 1.9 4.6 3.6 7.1 0.6 18.4 9.7 1.9 2.3 0.2 0.6 0.5 1.0 1.1 1.3 3.9 5.8 1.3 4.6 2.4 116.6 0.5 8.8 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 5 "HDLM-2: 58.9;Karpas-707: 73.0;RPMI-8226: 71.9;U-266/70: 133.0;U-266/84: 117.5" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favourable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.5 0.8 1.6 0.3 0.2 1.2 1.1 1.4 1.6 1.4 1.4 1.3 7.8 0.5 0.5 1.1 2.6 1.0 1.5 58.9 2.1 9.4 1.6 1.4 0.7 2.2 6.4 0.6 0.9 1.6 1.0 0.5 10.0 73.0 0.9 1.3 0.8 4.7 17.8 2.4 1.0 0.5 71.9 1.6 0.2 0.5 0.8 1.2 0.8 0.8 2.0 3.1 0.3 0.3 0.2 0.3 1.1 133.0 117.5 15.0 1.5 2.0 0.3 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol Cytosol "HPA068758: " "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favourable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.2 4.8 3.2 6.1 2.5 1.9 18.5 4.6 7.4 5.4 3.9 8.0 6.2 12.9 5.8 1.2 6.2 6.2 3.4 1.9 9.7 25.7 5.3 11.5 9.6 12.0 11.5 10.3 3.6 11.5 3.3 5.7 17.6 7.3 45.7 1.6 16.2 5.8 20.6 6.8 7.7 27.2 5.4 15.3 2.9 5.5 11.6 8.1 8.9 40.6 28.4 5.3 15.3 4.6 3.4 14.8 5.6 7.4 23.5 14.9 11.0 8.6 6.5 9.2 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 PINK1 PARK6 ENSG00000158828 "PTEN induced putative kinase 1" Q9BXM7 1 20633455-20651511 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.7" "Group enriched" "Detected in many" 4 "granulocytes: 10.7;monocytes: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Uncertain "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favourable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 17.9 35.9 38.9 6.7 38.0 6.0 10.1 16.8 45.0 9.8 13.0 17.8 10.0 15.2 9.3 9.8 20.7 10.7 11.4 51.4 31.0 28.7 20.2 26.1 10.0 5.1 39.5 27.1 11.6 24.3 16.3 7.1 13.9 31.0 12.4 7.7 10.6 23.9 15.4 142.0 10.8 12.7 10.8 30.2 8.3 10.5 27.2 16.8 3.3 16.0 21.5 4.6 12.7 9.5 1.2 1.4 10.7 4.4 0.7 1.7 0.8 17.9 8.2 3.8 11.0 13.4 12.7 4.0 25.2 25.4 12.3 21.4 2.8 14.6 4.2 20.0 25.7 8.3 5.6 13.4 6.1 5.0 21.2 2.1 22.9 4.4 10.4 2.2 6.7 11.9 14.5 15.3 5.3 7.9 5.1 5.4 8.8 7.6 3.2 5.1 1.7 27.0 2.8 6.8 3.3 7.6 4.2 14.3 5.6 27.5 9.1 7.6 3.0 7.8 12.0 11.1 5.7 18.5 3.5 6.3 1.2 1.9 24.1 6.5 5.2 4.8 2.2 4.7 1.1 1.4 1.4 0.3 1.0 1.5 0.7 1.2 0.8 1.1 10.7 0.7 4.4 1.4 1.7 0.8 38.9 38.0 16.8 45.0 31.0 28.7 39.5 27.1 31.0 16.8 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534849-22714555 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 92.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" 8800000 "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: , HPA068771: " "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 13.0 7.3 43.8 20.3 63.8 17.3 6.9 6.6 41.4 13.2 7.8 75.5 1.0 5.9 9.9 5.6 9.2 7.2 15.1 5.9 56.0 31.7 7.6 8.3 11.5 33.4 65.7 22.9 4.3 4.9 29.5 4.2 10.5 36.5 4.4 9.0 5.7 3.9 6.3 2.6 4.0 8.1 14.4 92.0 26.6 8.4 5.4 59.8 10.1 5.9 1.0 38.5 11.5 5.8 14.7 12.0 26.3 16.6 38.4 46.7 39.3 8.7 8.7 10.1 3.2 16.3 22.2 7.7 16.4 17.5 8.9 11.0 8.1 14.2 18.5 6.0 32.9 3.1 8.8 4.6 9.0 40.9 9.1 34.7 6.4 17.9 28.9 6.6 27.3 11.1 4.1 12.1 11.7 13.1 19.3 36.1 16.4 3.6 26.6 6.0 4.1 6.2 10.7 14.5 25.1 13.2 1.7 1.8 4.3 5.2 2.7 26.1 2.3 11.6 15.8 6.9 10.1 12.7 10.0 23.0 13.0 13.5 18.6 20.2 5.3 16.1 8.8 26.3 34.5 15.6 46.7 14.7 27.5 40.0 11.6 8.6 18.6 34.9 10.9 38.4 16.6 12.0 19.6 39.3 43.8 63.8 6.6 30.3 56.0 31.7 65.7 22.9 36.5 59.8 PIP4K2B "PIP5K2B, PIP5KIIB, PIP5KIIbeta" ENSG00000276293 "Phosphatidylinositol-5-phosphate 4-kinase type 2 beta" P78356 17 38765689-38800126 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 23.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047875, HPA062220" Approved Supported Nucleoplasm Nucleoplasm "HPA047875: , HPA062220: " "unprognostic (7.77e-2)" "unprognostic (8.37e-2)" "unprognostic (3.74e-2)" "unprognostic (1.13e-1)" "unprognostic (2.67e-1)" "unprognostic (1.91e-1)" "prognostic unfavourable (4.54e-4)" "unprognostic (2.64e-1)" "unprognostic (2.33e-1)" "unprognostic (1.50e-2)" "unprognostic (6.10e-3)" "unprognostic (3.79e-1)" "unprognostic (4.82e-3)" "unprognostic (3.38e-2)" "unprognostic (3.22e-1)" "prognostic favourable (1.36e-4)" "unprognostic (2.48e-1)" 5.1 6.5 12.4 3.3 12.9 1.1 5.0 8.8 17.4 6.8 2.7 7.0 4.2 2.2 7.2 5.9 3.5 7.4 3.6 7.1 9.6 4.1 2.2 5.0 4.2 5.4 13.3 13.3 3.0 5.1 2.7 5.4 7.5 5.1 3.2 4.1 3.8 6.5 23.6 5.8 2.3 7.3 4.7 5.1 2.5 2.8 6.5 2.0 4.7 2.2 4.5 3.7 5.9 3.3 3.1 2.4 2.4 3.4 5.0 3.7 5.9 13.1 21.8 22.7 19.1 15.2 4.5 11.1 12.4 14.1 11.5 8.8 5.9 15.2 7.0 19.0 12.8 14.4 9.2 13.6 10.5 9.3 13.2 8.5 13.0 8.7 15.1 8.1 13.3 11.3 11.0 8.1 11.6 11.5 7.2 15.1 4.5 13.8 11.0 12.2 6.1 15.0 21.6 8.3 10.3 7.4 12.2 17.7 11.2 4.6 11.3 14.4 14.3 12.3 11.9 7.9 10.2 9.6 9.5 11.9 6.9 14.1 11.9 10.7 1.6 2.4 0.8 4.8 2.2 5.0 3.1 4.1 4.6 3.1 3.3 4.7 4.2 2.4 3.4 1.8 3.0 3.9 3.7 PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028658, HPA058551" Approved Approved Vesicles Vesicles "HPA028658: AB_10601245, HPA058551: " "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavourable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favourable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" 9.3 13.3 13.9 9.2 25.9 16.7 15.0 18.9 45.5 12.5 17.5 14.6 15.8 11.6 14.2 62.0 20.0 20.0 12.1 10.8 15.4 10.9 26.9 14.4 14.4 9.2 14.3 21.2 12.3 14.9 29.6 13.7 11.1 18.8 16.7 19.4 17.4 18.6 14.6 9.4 18.4 13.3 11.9 12.7 10.7 27.6 25.6 12.1 5.9 17.9 8.5 13.1 14.6 14.1 6.8 5.4 29.7 8.4 9.4 16.1 6.5 18.8 13.4 5.4 6.5 0.0 0.0 17.5 7.9 14.8 14.3 13.3 16.9 27.3 4.1 17.3 9.2 17.3 8.9 15.5 11.5 6.1 10.0 7.4 6.5 11.9 12.6 6.8 13.3 4.9 26.4 5.4 10.1 7.2 9.5 12.4 7.4 18.6 6.1 5.9 10.3 11.6 0.1 49.2 6.1 15.0 32.4 9.1 11.3 17.0 11.4 10.8 31.1 6.4 1.6 7.2 10.0 10.5 8.3 9.6 11.1 9.2 14.2 5.8 11.9 29.7 5.2 15.3 16.1 6.2 10.7 5.9 9.9 12.0 5.4 6.8 9.6 11.5 10.2 9.4 8.4 2.3 12.1 6.5 13.9 25.9 18.9 45.5 15.4 10.9 14.3 21.2 18.8 12.1 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavourable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 18.1 19.5 15.7 15.4 21.0 9.6 20.2 22.6 27.6 19.8 18.0 20.3 14.7 16.4 24.8 22.6 20.7 19.4 20.7 18.9 17.3 13.4 17.8 18.3 21.7 17.1 12.7 17.5 20.4 16.6 21.8 25.3 44.6 14.6 17.3 15.6 29.5 17.8 15.2 26.1 20.4 20.4 27.2 16.1 20.1 16.8 42.1 14.0 19.3 20.1 13.9 22.3 16.2 17.7 9.1 8.7 11.7 6.2 4.7 5.9 6.3 17.7 13.8 21.4 24.6 14.1 14.9 21.0 23.4 33.0 43.8 39.3 25.1 17.2 16.1 25.0 24.9 15.1 27.7 16.1 38.4 24.3 19.8 12.8 18.2 11.9 26.7 22.9 16.2 19.9 14.9 27.2 34.5 17.8 12.5 13.8 22.0 24.8 22.8 11.4 31.7 21.4 22.1 18.7 12.0 22.5 10.3 14.3 19.0 31.6 24.4 20.6 25.5 21.7 17.0 17.4 24.4 16.0 28.1 19.3 32.1 36.4 16.9 6.7 20.8 0.1 5.5 7.3 5.3 6.2 4.1 9.1 5.0 5.9 8.4 4.6 5.4 4.2 11.7 4.7 4.8 8.7 3.9 6.3 15.7 21.0 22.6 27.6 17.3 13.4 12.7 17.5 14.6 14.0 PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705414-69009176 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 30.3;HEL: 11.3;Hep G2: 9.2;Karpas-707: 6.4;U-266/70: 11.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 22.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA009687: AB_1855391" "unprognostic (2.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-2)" "unprognostic (2.92e-2)" "prognostic favourable (1.03e-9)" "unprognostic (2.10e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" 4.0 9.5 9.4 8.4 6.5 10.2 4.2 33.4 14.6 5.6 26.9 4.1 10.8 26.1 6.1 2.0 1.2 5.0 7.6 24.6 8.1 11.7 6.1 0.8 12.6 2.1 10.4 6.4 1.4 6.7 21.3 8.5 16.8 32.8 3.3 23.1 28.7 11.6 13.6 3.0 2.4 39.7 2.6 3.7 3.1 19.9 17.6 1.5 0.0 1.6 1.9 3.3 3.5 2.9 3.9 0.9 22.1 0.3 0.0 1.0 0.2 0.0 0.0 30.3 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 3.2 0.0 2.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 11.3 0.2 9.2 0.0 0.6 2.8 0.0 1.3 0.0 0.0 0.1 0.5 6.4 0.2 0.7 0.0 0.1 1.5 0.9 0.9 0.1 0.1 0.2 2.3 0.6 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 11.7 2.2 1.4 0.0 2.1 0.0 3.1 0.3 22.1 0.0 0.0 0.0 3.3 0.2 0.0 0.1 3.9 0.5 0.0 1.2 0.0 0.1 0.9 1.0 0.2 9.4 6.5 33.4 14.6 8.1 11.7 10.4 6.4 32.8 1.5 PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700479 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Phagocytosis" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017168: AB_1855395" "unprognostic (1.20e-1)" "prognostic favourable (1.79e-4)" "unprognostic (1.36e-3)" "prognostic favourable (7.28e-5)" "unprognostic (7.03e-2)" "unprognostic (4.02e-3)" "unprognostic (5.80e-3)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-3)" "prognostic favourable (2.32e-4)" "unprognostic (1.51e-1)" "prognostic favourable (3.00e-4)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" 16.1 10.2 20.5 12.8 25.8 4.5 8.0 58.6 46.3 10.7 23.5 8.5 14.8 10.9 19.8 10.0 12.3 12.8 12.7 13.8 22.8 10.7 7.5 3.8 11.5 7.5 11.3 17.1 11.5 17.2 10.0 9.2 13.7 19.0 16.7 6.4 16.9 20.0 33.4 13.5 10.2 11.5 19.2 6.3 15.8 13.6 23.9 8.7 5.3 9.3 3.9 6.0 17.3 19.0 2.5 3.2 3.6 3.0 1.7 2.8 2.0 9.0 8.6 6.8 8.8 13.3 10.8 10.2 17.5 11.1 7.5 6.1 7.6 2.6 3.8 6.7 18.8 8.1 3.2 5.6 3.1 13.5 5.7 4.4 7.1 6.2 11.0 4.4 13.5 12.0 5.4 6.1 2.3 12.8 6.6 7.1 7.1 7.5 5.3 3.3 7.0 12.0 10.0 5.2 5.2 5.6 7.8 6.8 5.9 9.1 4.9 5.3 3.9 6.6 28.0 10.6 6.0 37.3 8.1 8.2 6.5 1.7 14.3 9.3 7.6 3.6 2.8 0.0 2.8 2.6 1.2 2.5 2.1 2.0 3.2 1.3 1.0 1.6 2.2 1.7 3.0 2.2 1.4 2.0 20.5 25.8 58.6 46.3 22.8 10.7 11.3 17.1 19.0 8.7 PIP5KL1 "bA203J24.5, MGC46424" ENSG00000167103 "Phosphatidylinositol-4-phosphate 5-kinase like 1" Q5T9C9 9 127920879-127930797 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Karpas-707: 28.9;RPMI-8226: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 1.2;MAIT T-cell: 1.0;memory B-cell: 1.0;myeloid DC: 1.0;naive B-cell: 2.4;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA056240 Uncertain Supported Cytosol Cytosol "HPA056240: " "unprognostic (2.15e-2)" "unprognostic (3.06e-1)" "unprognostic (1.23e-3)" "unprognostic (8.51e-5)" "unprognostic (1.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (5.20e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.57e-3)" "unprognostic (9.95e-8)" "unprognostic (1.87e-1)" "unprognostic (7.21e-2)" "unprognostic (6.05e-2)" "unprognostic (1.59e-1)" 0.6 0.7 3.1 0.6 1.0 1.4 2.5 2.4 5.3 2.1 0.6 1.9 0.6 0.5 1.3 0.6 3.7 1.8 1.2 0.6 2.1 2.9 1.3 0.6 2.9 0.6 1.4 2.6 0.7 1.3 6.5 4.8 1.6 8.3 3.3 0.2 1.0 8.7 4.1 0.6 4.7 0.6 1.0 1.5 0.6 2.4 2.5 1.2 0.6 2.9 0.6 0.6 1.2 4.0 2.4 1.3 0.0 1.2 0.0 1.0 0.3 0.0 0.4 0.4 0.5 0.5 1.3 2.7 0.6 0.5 0.1 0.1 0.2 3.5 0.3 1.1 2.3 1.1 0.0 2.6 0.1 0.3 1.7 0.0 0.8 0.0 0.8 0.0 0.1 1.4 1.7 0.3 0.0 0.0 0.0 28.9 0.0 2.4 0.0 1.0 0.2 0.4 0.2 0.0 18.9 0.0 0.0 0.9 1.7 0.1 0.7 0.0 1.0 1.3 0.3 0.3 1.0 0.6 0.1 2.6 1.7 0.6 5.2 0.4 0.3 0.0 0.0 0.0 0.0 1.2 1.0 1.0 0.1 0.0 1.0 2.4 0.2 0.1 0.0 0.0 0.1 1.3 0.0 0.3 3.1 1.0 2.4 5.3 2.1 2.9 1.4 2.6 8.3 1.2 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 98.7" "Cell line enhanced" "Detected in many" "HAP1: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 12.6 9.9 21.6 5.5 35.7 2.6 7.9 13.4 23.7 12.2 5.8 8.9 19.3 4.7 9.2 98.7 5.7 10.2 7.1 7.5 18.4 23.4 7.5 4.4 7.4 5.9 14.9 16.7 16.2 6.0 27.1 12.5 10.7 11.7 9.9 5.3 7.2 6.4 20.3 4.7 7.1 4.4 9.8 12.0 5.9 6.5 13.7 9.5 3.0 13.8 2.9 7.4 7.8 7.9 11.2 4.3 2.7 4.5 14.8 17.8 9.0 10.4 8.0 25.1 17.5 8.8 9.3 7.5 7.0 8.4 6.6 8.9 6.5 9.9 1.6 10.9 11.0 9.1 38.5 13.6 8.3 7.8 13.7 3.1 6.6 4.3 11.0 1.8 6.0 9.7 9.1 11.2 6.7 7.4 2.9 1.1 6.7 5.6 0.8 3.5 17.1 13.1 7.5 11.2 2.5 10.6 8.8 18.6 12.1 11.2 1.9 8.5 3.1 2.6 6.7 5.7 9.2 16.9 3.2 0.0 0.1 3.8 6.2 5.1 7.6 2.7 3.3 1.0 15.5 4.5 17.8 8.7 13.7 14.2 3.6 11.2 14.4 16.6 1.1 14.8 2.9 4.3 8.3 9.0 21.6 35.7 13.4 23.7 18.4 23.4 14.9 16.7 11.7 9.5 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334709-109409994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: " "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavourable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 21.6 27.0 40.1 15.9 49.9 29.0 22.1 41.6 63.0 29.0 23.8 19.7 16.8 12.5 29.2 25.0 20.7 20.3 18.6 24.4 44.3 46.2 24.1 29.2 19.4 14.3 36.8 44.0 35.4 14.8 42.8 30.3 21.8 53.2 31.7 20.6 12.5 17.3 37.7 17.1 13.6 15.9 39.2 37.6 19.5 15.8 17.0 27.4 16.7 35.9 9.7 16.3 35.5 21.4 10.3 11.7 29.9 15.5 10.7 12.2 10.6 11.8 8.2 33.1 25.4 32.9 36.1 18.0 19.4 29.4 15.4 25.3 7.6 16.1 15.2 27.0 37.3 6.9 19.3 24.0 28.3 12.9 7.3 17.5 16.8 10.2 23.3 13.1 26.2 24.8 20.1 20.6 29.6 24.5 12.0 28.7 24.8 7.2 15.7 12.1 6.6 5.5 10.2 29.1 25.3 24.0 10.6 6.3 16.3 20.0 7.3 23.4 16.5 19.4 28.2 21.9 10.7 20.2 9.1 19.4 16.5 18.0 23.2 18.3 14.4 17.3 11.6 17.3 9.5 12.2 9.4 10.3 9.4 8.7 11.7 7.4 12.1 8.9 29.9 10.7 15.5 4.9 12.2 10.6 40.1 49.9 41.6 63.0 44.3 46.2 36.8 44.0 53.2 27.4 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048020-42058528 "Enzymes, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 30.5;ASC diff: 24.2;CACO-2: 36.1;HHSteC: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" 10000 "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 21.4 5.7 1.9 8.4 1.8 0.8 18.9 0.3 4.7 20.8 13.7 1.7 6.3 9.3 17.6 16.0 9.2 10.0 29.6 17.0 2.3 0.7 4.7 3.5 8.0 3.7 3.7 0.3 43.6 3.3 0.9 3.2 3.2 2.6 13.0 5.2 17.0 38.6 5.6 40.2 1.7 7.7 26.2 2.3 4.6 4.8 14.1 2.3 4.2 3.1 13.1 2.1 22.8 23.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 5.4 30.5 24.2 0.3 1.9 0.1 0.0 0.4 0.6 36.1 0.0 0.0 0.1 0.6 0.0 0.5 0.0 0.0 2.9 1.2 0.0 1.3 9.5 20.8 0.0 0.4 2.1 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 8.9 0.6 0.0 10.5 0.0 0.0 0.0 1.1 1.9 0.5 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.3 4.7 2.3 0.7 3.7 0.3 2.6 2.3 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301434 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.2;kidney: 12.4;liver: 47.8" "Cell line enriched" "Detected in some" 9 "K-562: 47.4" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Low region specificity" "Detected in some" "HPA006653, CAB034376, CAB034378" Enhanced Approved "Golgi apparatus,Cytosol" 2900000 "Golgi apparatus, Cytosol" "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: " "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.1 0.0 0.1 0.3 0.1 7.2 0.1 0.9 0.2 0.1 4.9 0.1 0.1 5.8 0.1 1.3 0.1 0.0 0.7 0.1 0.1 0.4 12.4 47.8 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.6 17.2 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.4 0.1 0.1 0.1 0.1 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 541.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol 540000000 Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (1.30e-4)" "prognostic unfavourable (2.74e-6)" "prognostic unfavourable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavourable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 23.2 76.8 53.8 49.8 70.4 57.5 41.6 56.6 85.9 65.7 31.2 32.1 31.5 26.4 24.7 41.8 76.4 37.9 32.9 94.8 50.1 57.1 60.9 6.1 33.3 39.4 62.5 63.6 26.2 15.6 33.3 28.3 27.1 80.5 34.8 31.9 54.4 47.1 47.5 541.2 51.8 25.1 44.7 34.9 30.7 26.7 29.0 29.4 23.5 23.8 114.4 60.6 53.1 40.9 25.1 79.6 14.9 90.6 11.6 37.4 114.9 81.5 209.8 42.3 50.0 50.9 57.2 35.0 88.5 206.7 142.1 143.9 59.0 100.5 62.1 89.6 165.6 118.9 133.7 180.0 111.4 109.0 63.2 38.0 105.5 48.8 35.5 49.3 82.0 51.9 83.9 109.5 45.0 83.6 9.5 49.8 224.1 50.7 18.4 21.2 52.3 80.1 54.7 135.4 118.3 188.7 105.0 44.0 48.0 115.4 71.2 90.5 49.9 35.9 65.1 161.9 88.6 158.2 160.5 64.0 90.4 54.7 199.3 81.6 158.6 12.6 90.6 14.9 23.5 52.6 22.8 25.1 31.3 23.2 79.6 16.1 27.3 20.2 11.8 11.6 40.2 16.2 37.4 114.9 53.8 70.4 56.6 85.9 50.1 57.1 62.5 63.6 80.5 29.4 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.5;lymphoid tissue: 42.8;testis: 61.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 4.4" "Lineage enriched" "Detected in single" 5 "T-cells: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: " "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavourable (8.33e-4)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 0.9 0.7 0.7 9.4 0.6 19.5 1.3 2.6 0.8 1.3 2.9 0.3 0.5 1.9 0.8 1.5 7.2 0.2 1.5 1.4 0.7 0.7 0.8 1.0 1.3 6.2 0.8 0.2 0.3 1.3 0.0 0.7 4.3 0.4 0.6 0.8 0.3 1.3 0.2 1.6 3.4 3.2 0.6 1.0 4.4 2.7 61.4 0.2 42.8 0.3 9.2 12.7 0.7 2.0 0.8 0.4 0.3 0.5 0.4 4.4 1.0 24.6 17.3 6.8 9.7 0.1 0.3 18.3 19.2 4.6 12.2 11.7 13.4 14.7 15.4 8.6 2.1 31.7 4.7 6.1 2.2 19.8 15.6 7.8 15.6 11.7 0.0 8.7 22.3 0.2 0.5 7.2 1.9 2.5 22.4 27.4 3.9 37.0 24.4 24.2 11.1 9.2 26.6 15.1 29.8 2.3 5.4 12.9 13.6 9.3 24.2 7.2 13.8 17.4 2.3 16.4 20.8 23.9 20.0 20.8 15.4 26.5 6.2 11.7 19.0 0.0 0.4 0.3 0.3 0.3 0.0 0.8 0.5 0.5 0.4 0.0 0.0 0.0 0.1 0.4 0.5 0.1 4.4 1.0 0.7 0.6 2.6 0.8 0.7 0.7 0.8 0.2 0.4 0.2 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.2 22.2 8.3 17.2 13.4 15.8 13.7 13.4 16.1 14.2 13.6 8.6 21.4 35.6 34.8 23.0 8.6 13.2 6.0 5.5 28.8 17.1 42.6 14.2 18.4 44.5 16.7 26.8 11.4 4.3 8.6 13.5 32.9 18.8 24.7 10.4 15.3 25.2 15.5 15.0 25.4 33.9 11.3 25.6 7.0 6.1 30.2 42.8 8.3 10.6 21.7 9.6 29.2 49.2 28.3 12.1 34.1 20.3 32.5 29.6 19.4 18.5 33.6 22.1 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 35.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: , HPA057913: " "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favourable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 21.9 20.7 12.2 21.2 13.7 33.5 27.6 25.6 16.6 28.6 39.3 12.6 15.1 22.9 20.0 20.2 28.2 17.1 13.3 16.2 10.3 8.9 15.9 15.9 26.0 16.4 13.7 8.7 27.2 18.9 24.6 29.7 20.8 13.3 19.6 23.6 14.1 19.5 25.1 15.9 17.5 49.0 17.5 12.5 18.0 15.9 12.4 16.2 29.1 20.3 14.4 13.1 21.9 22.0 4.0 3.7 35.7 4.5 1.4 3.0 1.0 23.3 9.2 18.2 10.9 12.2 13.9 11.8 13.8 12.8 15.6 16.2 9.7 16.8 9.2 16.5 13.1 18.4 17.7 10.5 21.3 3.3 12.9 6.8 19.0 8.3 10.7 6.7 2.0 11.4 11.0 12.2 14.8 17.7 11.3 6.7 16.7 4.7 7.7 5.8 9.1 10.7 7.4 27.7 3.8 13.8 46.0 8.8 5.8 20.7 12.0 17.8 8.9 6.1 16.5 13.2 11.9 16.9 14.4 3.7 3.2 6.3 5.5 6.6 5.0 4.9 4.5 6.8 2.6 2.5 2.3 3.3 2.3 2.4 2.1 4.0 3.0 2.6 35.7 1.4 3.2 3.7 1.8 1.0 12.2 13.7 25.6 16.6 10.3 8.9 13.7 8.7 13.3 16.2 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702523-128720918 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045390, HPA058305" Uncertain Approved Vesicles Vesicles "HPA045390: , HPA058305: " "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 11.4 1.8 1.5 6.8 3.8 3.7 10.5 10.1 3.9 4.3 5.8 3.7 4.8 7.7 9.7 2.2 7.1 5.3 10.9 7.3 2.3 1.7 5.0 6.4 8.9 9.1 3.9 1.2 4.0 4.2 3.3 1.4 5.6 4.5 4.2 1.6 4.1 12.9 3.7 7.4 6.7 5.4 4.9 4.4 7.8 7.4 4.3 1.7 9.3 8.1 6.1 5.9 4.4 5.0 0.4 1.0 2.3 0.7 1.0 1.8 0.3 1.3 6.7 5.5 8.3 0.0 0.1 13.6 4.2 1.3 6.2 6.4 0.0 4.9 0.0 4.1 2.2 9.1 6.7 1.0 1.4 4.2 12.6 8.0 32.8 9.6 1.0 1.0 1.4 0.3 0.3 3.3 0.9 12.2 18.3 0.9 1.1 12.6 1.2 4.3 5.1 2.0 19.9 10.4 1.8 2.6 0.8 0.9 4.1 3.1 1.7 3.1 5.9 6.4 10.5 0.0 5.2 9.7 3.1 3.0 1.3 2.6 0.7 1.0 3.8 0.0 0.1 1.4 0.9 0.7 1.8 0.2 0.6 0.8 1.0 0.4 0.8 0.1 2.3 1.0 0.2 0.2 1.0 0.3 1.5 3.8 10.1 3.9 2.3 1.7 3.9 1.2 4.5 1.7 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 83.9;testis: 32.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "T-reg: 9.0" "Lineage enriched" "Detected in many" 5 "T-cells: 9.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051638, HPA053229" Approved "HPA051638: , HPA053229: " "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavourable (2.70e-7)" "prognostic unfavourable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavourable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 2.9 1.1 1.1 14.2 1.5 15.9 1.7 2.1 1.1 1.5 7.1 0.7 0.5 6.0 1.1 0.9 10.4 0.7 1.5 1.0 1.0 0.8 1.3 1.2 2.6 15.2 0.8 0.6 1.2 0.7 0.0 0.8 6.8 0.7 0.9 5.9 0.5 1.7 0.8 0.8 2.9 5.9 2.0 0.7 8.3 3.6 32.4 0.5 83.9 0.6 6.6 20.4 2.1 2.6 1.9 0.5 0.7 0.1 1.3 9.0 2.3 43.1 45.0 37.2 20.2 1.1 2.6 20.9 24.7 16.3 38.7 28.9 39.3 28.5 21.6 12.9 16.6 24.8 50.7 20.3 46.6 30.7 28.6 27.4 35.5 53.7 0.3 31.6 30.1 1.0 1.1 27.4 28.3 28.3 42.6 29.8 29.8 39.4 29.7 31.6 42.5 22.9 46.5 25.3 34.3 11.0 9.4 21.0 14.6 28.2 19.8 12.8 25.2 19.5 14.3 18.4 23.6 18.0 42.1 21.2 33.0 37.4 15.6 27.5 30.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 1.4 0.5 0.5 0.0 0.0 0.0 0.7 1.3 0.0 0.0 9.0 2.3 1.1 1.5 2.1 1.1 1.0 0.8 0.8 0.6 0.7 0.5 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460260 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 42.9;T-47d: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 11.4 3.7 19.6 4.0 40.2 4.4 23.4 1.3 39.4 20.6 5.7 3.7 5.0 5.1 19.2 7.1 17.7 9.5 18.2 28.1 18.8 5.1 6.9 17.6 17.7 3.8 4.2 20.6 11.8 12.6 3.8 3.3 25.9 8.7 8.7 8.7 12.6 22.1 6.2 8.7 20.9 6.1 15.4 2.7 54.7 4.7 19.8 7.4 1.0 8.9 16.6 7.5 14.2 15.5 1.2 2.9 3.0 1.6 10.4 1.2 0.6 22.9 20.7 7.2 0.5 3.8 6.2 2.8 4.9 8.2 16.3 9.5 1.5 20.3 0.0 32.3 17.6 28.8 0.3 11.3 14.9 0.0 0.6 0.0 9.3 1.7 20.7 0.1 0.6 3.6 15.7 6.3 17.6 32.8 0.0 0.8 32.2 8.3 0.0 0.0 1.3 3.4 1.1 20.0 0.0 42.9 4.6 0.4 0.9 15.1 3.0 13.2 72.3 0.3 41.8 4.5 12.2 2.0 39.1 0.0 0.0 0.0 3.5 0.0 20.0 3.0 0.7 2.3 0.1 1.6 0.0 1.2 0.7 0.0 2.9 0.9 1.2 0.6 1.9 10.4 0.6 2.0 0.5 0.6 19.6 40.2 1.3 39.4 18.8 5.1 4.2 20.6 8.7 7.4 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800225-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced "HPA060318: " "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavourable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 14.8 7.6 4.4 16.3 18.8 8.6 10.0 2.4 6.4 8.6 5.3 13.9 3.2 4.0 9.9 5.8 23.9 8.5 21.6 6.8 10.5 6.0 6.7 9.0 14.9 10.0 9.9 2.5 7.8 10.7 15.6 9.0 29.6 14.8 6.4 4.0 7.6 8.2 6.8 7.0 16.6 7.0 6.0 15.2 9.1 6.1 4.5 5.6 4.6 8.4 25.0 18.2 9.9 9.5 1.3 4.2 2.8 5.1 0.6 11.0 3.5 4.1 2.7 4.2 1.9 3.1 10.2 7.8 9.8 13.8 3.7 3.8 1.6 5.9 5.1 4.1 8.0 3.8 2.3 13.4 2.1 8.2 0.7 5.6 1.5 3.6 15.3 1.8 7.2 7.9 8.0 11.1 10.9 11.7 2.9 2.1 8.4 2.7 3.7 1.6 2.8 3.3 4.4 2.8 7.3 13.3 1.6 3.2 2.0 2.6 4.6 10.8 0.4 1.8 14.9 2.3 5.7 4.5 5.7 5.9 2.7 1.3 4.9 2.9 4.5 0.0 2.9 0.8 1.7 5.0 2.1 1.3 9.9 4.2 4.2 1.1 11.0 4.9 2.8 0.6 5.1 1.8 10.5 3.5 4.4 18.8 2.4 6.4 10.5 6.0 9.9 2.5 14.8 5.6 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880861-127899195 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5;lymphoid tissue: 21.7;testis: 21.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol "Centrosome, Cytosol" "HPA017327: , HPA035026: AB_10602080, HPA043198: " "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favourable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavourable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.4 1.3 1.5 4.7 2.4 16.5 2.2 0.5 2.2 2.0 3.2 0.3 0.6 2.3 1.3 1.3 5.4 1.1 1.2 2.0 1.2 1.3 1.5 0.9 1.5 5.9 1.2 1.4 1.5 0.9 0.3 0.6 5.0 2.6 1.4 3.7 0.8 1.7 0.7 0.4 2.7 3.2 1.9 1.8 2.7 1.6 21.7 1.0 21.7 1.0 2.1 6.0 1.5 2.2 0.7 0.7 1.5 0.8 1.4 4.0 0.8 11.6 5.5 20.7 10.6 0.7 2.0 9.4 11.4 8.1 15.2 15.8 7.7 12.0 15.7 4.2 6.3 7.7 14.6 9.1 23.5 12.2 6.0 14.2 8.8 7.2 0.2 20.0 16.9 0.6 0.9 13.9 6.4 11.7 16.5 21.0 12.8 8.1 30.8 9.0 9.6 6.3 16.1 14.5 5.4 5.0 7.4 11.5 9.4 7.2 6.6 3.5 5.3 8.7 5.0 12.0 11.6 8.1 14.2 10.9 11.9 22.4 6.1 15.3 13.2 0.0 0.4 1.5 1.6 0.8 1.1 0.3 1.8 1.7 0.7 0.7 0.6 2.3 0.0 1.4 0.3 0.4 4.0 0.8 1.5 2.4 0.5 2.2 1.2 1.3 1.2 1.4 2.6 1.0 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924734-154936991 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favourable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favourable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 21.0 28.3 31.3 15.9 34.0 7.2 19.4 13.9 31.7 17.0 18.9 25.3 10.2 26.4 12.1 14.7 30.1 20.2 15.7 24.7 23.9 23.9 26.9 39.3 16.2 18.7 29.6 29.3 18.8 22.2 26.8 26.1 13.8 22.4 17.0 12.0 22.2 18.8 15.9 39.8 26.1 25.2 16.7 23.9 20.5 21.8 15.9 22.8 9.9 17.8 25.3 18.9 12.2 22.8 29.1 22.9 20.4 47.3 13.4 30.4 17.7 11.6 16.4 10.6 16.6 9.8 7.0 11.3 9.4 6.4 8.6 8.3 6.6 23.1 16.6 18.1 10.6 11.4 14.3 13.9 4.0 23.2 6.6 7.6 22.2 6.2 9.1 11.5 6.9 8.3 13.0 15.6 11.1 8.7 8.0 51.4 8.9 23.2 9.0 11.1 9.6 21.1 13.7 6.9 38.1 14.5 8.5 8.9 21.3 10.1 17.6 11.5 33.7 20.4 7.3 8.4 6.9 19.9 14.0 41.8 33.3 29.2 13.9 18.5 10.8 4.6 19.8 20.4 17.5 46.9 27.9 29.1 24.0 17.8 22.1 23.9 15.7 15.7 1.7 13.4 47.3 22.9 30.4 17.7 31.3 34.0 13.9 31.7 23.9 23.9 29.6 29.3 22.4 22.8 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell line enriched" "Detected in some" 8 "AN3-CA: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 26.5 0.0 0.0 2.8 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.1 0.0 0.1 2.1 0.2 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favourable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 12.8 8.7 8.8 13.8 8.4 6.5 14.3 20.8 10.6 9.6 8.4 6.9 16.9 8.3 6.6 6.3 10.5 3.1 11.7 5.7 10.7 13.3 14.1 16.4 6.0 6.3 13.3 19.0 6.1 6.2 8.7 5.7 12.6 6.9 16.8 12.5 8.2 13.5 10.7 8.2 17.7 11.5 8.1 16.8 9.9 27.5 10.4 16.8 9.1 27.4 4.6 4.7 8.3 17.8 18.8 11.5 4.5 17.1 18.6 7.5 6.7 17.0 6.0 14.9 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 PNMT PENT ENSG00000141744 "Phenylethanolamine N-methyltransferase" P11086 17 39667981-39670475 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 94.6;ductus deferens: 53.7;seminal vesicle: 40.7" "Cell line enhanced" "Detected in some" "HEL: 4.7;K-562: 10.2;NB-4: 20.2;NTERA-2: 3.9;SCLC-21H: 5.5;SH-SY5Y: 5.0" "Cancer enhanced" "Detected in many" "cervical cancer: 27.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 2.5" "Group enriched" "Detected in many" 5 "B-cells: 1.0;T-cells: 2.5" "Region enhanced" "Detected in some" "basal ganglia: 1.3" "Low region specificity" "Detected in single" "CAB017029, HPA043412, HPA051005" Enhanced "CAB017029: , HPA043412: AB_2630373, HPA051005: AB_2681306" "unprognostic (1.50e-1)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (3.95e-5)" "unprognostic (4.27e-2)" "unprognostic (3.02e-1)" "unprognostic (2.98e-2)" "unprognostic (5.75e-2)" "unprognostic (5.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (1.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.97e-1)" "unprognostic (4.72e-2)" "unprognostic (1.87e-2)" 2.3 94.6 3.9 0.8 13.8 1.6 5.4 0.9 3.0 1.3 1.9 1.5 53.7 0.9 1.0 2.7 0.9 1.9 0.8 4.9 1.7 5.4 1.0 0.7 1.6 0.8 9.1 1.5 0.9 0.7 2.4 12.9 2.4 3.6 4.3 0.7 0.9 0.7 40.7 10.5 0.8 1.0 0.8 0.7 0.9 0.9 1.3 2.7 0.0 0.7 0.8 0.7 1.3 1.7 1.0 0.0 0.3 0.3 0.0 2.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.4 4.7 0.1 0.4 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 20.2 3.9 0.0 0.1 0.0 0.3 0.0 0.0 5.5 5.0 0.0 2.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.4 1.0 0.4 1.5 0.0 0.4 0.0 0.7 0.3 0.0 0.3 0.0 0.0 0.3 3.9 13.8 0.9 3.0 1.7 5.4 9.1 1.5 3.6 2.7 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477094 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 153.1" "Cell line enhanced" "Detected in many" "HL-60: 81.4;U-937: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol 100000000 Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favourable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 24.7 7.6 9.5 15.0 14.0 69.4 15.7 13.9 11.8 9.5 19.1 6.2 25.2 29.4 5.9 153.1 34.0 7.8 15.7 12.1 11.5 8.4 49.7 24.2 18.3 13.2 13.5 3.4 3.6 11.0 8.7 8.4 45.3 17.7 6.0 16.1 3.8 9.2 7.9 3.3 10.6 32.0 9.8 16.3 18.0 17.0 4.5 12.5 7.0 7.1 21.7 19.1 7.5 14.7 13.1 20.7 4.1 12.4 15.7 33.7 12.1 13.2 17.9 3.8 8.6 4.3 3.5 11.7 13.6 6.4 11.1 11.0 10.3 12.2 35.4 15.8 7.2 14.3 20.1 25.6 14.8 11.4 17.7 29.6 15.3 17.0 4.0 81.4 15.4 2.3 9.3 33.5 14.8 47.3 14.5 22.1 13.9 12.3 23.9 48.0 10.8 29.9 20.2 5.7 13.7 39.4 12.6 16.6 3.7 26.0 33.2 2.1 12.2 14.5 37.9 7.6 10.1 17.1 23.0 10.2 17.0 40.1 6.5 92.8 0.7 4.0 12.4 4.1 18.1 11.5 33.7 11.2 20.3 20.0 20.7 13.1 12.9 16.3 1.6 15.7 10.6 11.7 6.9 12.1 9.5 14.0 13.9 11.8 11.5 8.4 13.5 3.4 17.7 12.5 PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634265-55693910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease mutation, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033424, HPA034602, HPA034603" Supported Enhanced Mitochondria Mitochondria "CAB033424: AB_2299801, HPA034602: AB_2674243, HPA034603: AB_10603130" "unprognostic (9.09e-2)" "unprognostic (7.40e-2)" "unprognostic (2.30e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (3.40e-2)" "unprognostic (1.03e-2)" "prognostic unfavourable (1.95e-7)" "unprognostic (1.88e-1)" "unprognostic (5.93e-3)" "unprognostic (5.23e-2)" "prognostic unfavourable (5.44e-5)" "unprognostic (2.19e-2)" "unprognostic (2.11e-2)" "unprognostic (6.92e-2)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" 11.1 11.7 13.3 6.5 21.7 11.7 10.8 13.3 18.8 5.7 8.2 12.8 5.4 5.7 8.3 8.8 9.5 7.9 5.8 11.0 12.4 10.9 9.8 11.4 9.1 7.1 24.1 7.4 6.9 9.1 7.4 14.3 5.1 15.2 7.7 10.1 4.2 9.0 6.3 23.5 10.1 7.0 7.9 17.6 10.4 7.6 13.5 22.5 9.6 10.0 7.8 5.9 5.3 7.4 9.8 7.4 6.1 6.5 3.8 8.6 4.7 6.7 3.6 5.0 2.3 3.6 6.3 6.7 10.0 6.1 15.9 10.7 10.5 3.2 14.1 4.2 4.7 5.4 6.4 7.8 7.4 5.0 14.2 8.1 4.6 5.3 9.5 18.3 5.5 7.0 5.4 6.6 5.7 4.9 8.5 3.2 6.3 3.8 11.2 12.8 12.1 6.1 11.1 8.4 12.4 6.7 4.2 12.2 7.3 3.6 11.1 12.2 3.0 8.1 5.1 3.8 3.2 3.3 10.2 14.3 1.1 3.0 7.2 16.0 6.4 4.2 6.5 6.1 8.1 5.7 4.8 5.4 3.7 8.6 2.8 9.8 6.9 7.9 6.1 3.8 5.1 7.4 2.4 4.7 13.3 21.7 13.3 18.8 12.4 10.9 24.1 7.4 15.2 22.5 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238667 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "monocytes: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" 140000 Centrosome "HPA054519: , HPA059935: " "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 15.9 13.5 8.2 15.5 8.9 7.4 19.4 6.6 11.3 15.5 20.2 13.1 10.4 16.4 18.1 19.6 13.9 17.4 23.6 20.1 7.5 6.3 18.8 44.6 14.8 22.2 8.8 6.6 18.3 24.6 19.2 11.3 22.4 7.8 16.0 16.0 16.9 13.3 16.0 13.5 13.3 27.5 20.8 7.7 12.4 12.5 16.5 7.0 12.7 20.1 13.9 13.0 15.7 12.6 2.8 3.9 3.3 16.4 1.7 3.3 3.2 15.0 12.1 10.5 11.5 18.1 17.7 19.7 15.6 18.6 26.4 17.4 36.2 20.4 10.2 23.6 17.4 16.8 10.1 19.3 23.0 5.2 6.3 15.2 11.1 16.4 14.1 13.0 9.7 15.5 15.3 20.0 13.1 14.7 11.4 5.8 18.4 7.4 8.9 10.0 5.4 19.7 7.5 28.0 9.4 8.1 10.0 6.9 8.9 35.9 10.0 13.3 14.8 15.6 12.7 38.4 14.3 24.0 26.5 7.2 9.1 9.4 23.2 45.3 24.2 3.3 4.4 2.1 2.9 12.8 3.3 2.8 2.6 2.7 3.9 2.4 3.3 2.4 0.9 1.7 16.4 2.9 2.7 3.2 8.2 8.9 6.6 11.3 7.5 6.3 8.8 6.6 7.8 7.0 POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" "HPA044297: AB_10965176" "unprognostic (1.32e-2)" "unprognostic (1.65e-3)" "prognostic unfavourable (4.55e-7)" "unprognostic (1.49e-2)" "unprognostic (4.09e-3)" "unprognostic (5.03e-2)" "prognostic unfavourable (2.78e-4)" "unprognostic (2.62e-1)" "unprognostic (2.15e-1)" "unprognostic (4.16e-2)" "unprognostic (4.20e-3)" "unprognostic (1.48e-2)" "prognostic unfavourable (8.66e-12)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.25e-2)" 12.9 15.3 11.3 13.1 12.4 14.8 16.1 8.7 11.9 15.2 12.8 14.5 12.0 11.6 19.7 23.2 7.0 16.3 15.5 13.7 12.1 11.7 13.7 14.5 16.1 8.7 13.5 7.3 24.6 17.3 12.7 28.1 20.6 12.2 15.3 8.0 16.6 17.1 15.7 6.3 8.3 11.7 15.0 8.5 12.8 13.3 24.2 10.0 7.7 19.4 8.9 8.6 12.0 12.9 1.5 2.0 3.8 1.9 1.6 2.6 1.5 4.2 4.8 9.6 10.7 17.6 16.4 4.5 24.4 19.8 11.7 17.2 10.3 7.4 3.0 18.5 40.6 4.4 5.7 9.8 12.7 5.0 6.7 6.0 6.8 8.2 20.3 4.4 8.0 11.6 6.6 14.4 7.8 11.4 5.6 4.9 11.7 4.4 2.2 7.4 12.8 7.0 4.5 2.9 3.8 6.2 4.0 4.2 6.2 14.4 8.8 8.8 6.4 6.4 12.1 8.5 8.4 13.5 10.8 12.1 6.3 2.4 18.0 5.6 13.7 1.7 1.7 3.8 1.7 1.9 2.6 1.1 1.9 1.5 0.5 1.5 2.2 2.2 2.5 1.6 1.5 2.0 1.7 1.5 11.3 12.4 8.7 11.9 12.1 11.7 13.5 7.3 12.2 10.0 POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468938-119494708 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" "Endoplasmic reticulum" Cytosol "HPA037855: AB_10672728, HPA037856: AB_2732477" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (6.52e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (7.02e-7)" "unprognostic (3.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "prognostic favourable (2.23e-4)" 11.9 12.1 7.6 10.7 12.0 3.9 10.9 13.9 10.6 10.1 9.5 9.8 27.4 5.9 13.7 11.7 9.3 10.1 6.9 8.3 7.3 8.9 8.3 10.3 9.1 14.3 15.0 5.6 10.5 29.2 12.1 14.5 11.5 10.9 9.4 10.9 8.7 7.8 25.7 5.1 14.0 12.1 15.2 14.0 14.9 8.2 4.7 8.9 11.7 8.6 4.1 15.6 10.6 10.2 9.9 14.3 9.4 11.5 19.8 16.0 10.3 7.4 5.0 8.7 9.6 22.0 12.6 6.2 11.9 12.2 9.7 13.3 8.1 4.9 11.5 16.2 15.0 8.8 11.6 11.8 15.4 9.9 7.5 13.5 7.9 8.8 14.3 14.8 15.9 12.9 7.7 9.6 13.5 11.0 7.3 14.1 9.8 7.5 8.4 14.3 8.9 9.2 8.4 8.8 16.9 8.4 9.6 9.5 14.6 5.7 3.6 9.2 9.5 12.4 13.9 9.5 5.9 2.8 6.1 19.4 16.8 15.7 8.3 15.0 13.4 1.9 11.5 9.4 12.0 10.8 13.8 9.9 13.6 12.5 14.3 7.0 16.0 15.2 0.9 19.8 7.0 8.0 14.7 10.3 7.6 12.0 13.9 10.6 7.3 8.9 15.0 5.6 10.9 8.9 POLA1 "NSX, p180, POLA" ENSG00000101868 "DNA polymerase alpha 1, catalytic subunit" P09884 X 24693919-24996986 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication, Host-virus interaction" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002947, CAB012274" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB012274: , HPA002947: AB_1079652" "unprognostic (6.92e-2)" "unprognostic (4.43e-3)" "unprognostic (3.27e-3)" "unprognostic (1.53e-2)" "unprognostic (2.53e-1)" "unprognostic (1.49e-1)" "prognostic unfavourable (4.80e-5)" "unprognostic (1.87e-1)" "unprognostic (9.25e-3)" "unprognostic (2.48e-2)" "unprognostic (8.41e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-2)" "unprognostic (3.08e-1)" 10.5 5.5 8.0 15.0 10.2 14.3 10.9 12.0 9.6 10.1 9.7 11.8 5.8 5.7 11.2 7.7 10.2 8.9 5.5 9.3 7.8 6.6 6.1 4.9 7.2 12.7 10.3 4.5 12.9 7.3 8.5 8.5 10.7 8.7 7.3 11.0 7.5 7.9 9.3 22.4 9.3 7.5 9.7 13.1 9.0 7.9 5.7 10.0 30.1 7.0 8.5 14.7 9.9 10.6 4.6 2.5 1.2 4.6 2.7 3.8 1.7 14.0 10.5 13.9 11.2 2.6 3.1 3.1 10.5 5.8 11.3 13.0 8.7 7.4 18.0 3.6 4.5 11.6 26.4 8.5 15.3 9.3 11.2 13.4 20.5 6.5 1.1 17.5 7.2 2.0 1.8 14.1 4.1 5.8 12.3 9.2 7.8 9.8 19.0 5.9 13.5 8.8 17.1 36.5 13.6 4.1 9.3 12.6 7.8 12.4 5.9 5.6 11.6 5.8 4.6 10.0 6.9 19.1 10.0 5.5 7.9 14.5 5.8 8.3 11.1 0.0 2.0 1.2 3.0 4.6 2.9 4.6 3.4 3.8 2.5 3.2 2.4 2.4 0.6 2.7 1.3 1.6 3.6 1.7 8.0 10.2 12.0 9.6 7.8 6.6 10.3 4.5 8.7 10.0 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell line enhanced" "Detected in all" "HMC-1: 79.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 73.6" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104" Enhanced Uncertain Vesicles Vesicles "CAB011616: AB_731977, HPA049104: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavourable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.65e-4)" 5.5 8.6 10.1 9.5 10.7 21.9 13.5 73.6 16.6 7.0 5.5 5.8 6.0 4.9 6.2 11.2 12.4 6.3 11.3 16.3 9.8 9.6 7.2 15.8 9.1 11.8 8.4 10.3 10.3 7.7 10.3 11.6 5.0 10.9 11.4 6.3 6.8 22.1 6.9 36.6 10.8 4.9 6.6 10.0 8.1 6.4 29.5 5.4 9.7 7.7 17.2 10.1 11.5 9.2 4.9 33.8 25.1 9.4 7.9 7.2 4.2 10.8 6.5 11.3 22.5 6.3 6.0 9.5 6.9 8.0 11.5 10.6 9.1 12.7 9.8 8.8 4.4 5.5 9.4 8.1 14.2 6.4 10.2 7.1 5.4 12.3 9.7 5.0 79.7 5.3 9.6 8.5 10.0 8.7 15.5 6.3 11.1 6.4 20.7 14.2 15.2 7.5 11.9 11.4 8.4 21.6 8.8 6.4 11.7 8.2 5.5 20.9 14.7 8.6 4.8 5.5 7.7 13.7 6.7 9.2 15.3 13.9 5.5 10.7 14.3 12.5 5.9 17.3 4.9 7.2 5.5 4.9 5.2 5.3 6.1 4.5 5.8 5.4 25.1 7.9 9.4 33.8 7.2 4.2 10.1 10.7 73.6 16.6 9.8 9.6 8.4 10.3 10.9 5.4 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418016 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm Nucleoplasm "CAB004375: AB_675487, HPA046524: " "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 7.9 5.7 5.4 18.3 9.9 31.6 6.6 9.4 5.4 8.2 10.0 6.1 5.9 6.8 9.5 7.2 11.3 6.9 5.2 5.5 4.4 3.2 7.6 9.3 10.9 15.7 7.0 3.6 8.2 8.4 5.2 5.1 10.9 6.7 6.3 5.2 4.9 8.1 5.4 7.2 13.1 9.9 6.2 7.7 14.1 6.5 13.2 6.5 27.4 12.1 8.1 14.2 5.9 7.8 9.3 10.5 2.1 8.5 5.4 7.3 5.6 18.1 25.0 13.7 7.9 1.7 1.5 14.1 11.3 5.0 13.9 17.8 13.6 14.4 26.0 6.4 3.4 14.9 16.2 12.3 4.8 21.9 43.5 22.6 24.2 17.9 1.6 21.5 20.0 2.9 3.8 12.6 3.8 7.1 24.3 20.2 5.8 12.2 33.3 33.7 16.1 18.2 33.1 23.0 22.8 4.4 17.3 14.3 12.9 11.2 13.8 2.6 7.6 20.4 5.6 7.1 23.0 7.6 19.8 19.1 31.4 27.8 7.7 24.3 6.9 1.6 6.2 2.1 7.3 7.8 6.2 7.8 6.5 5.9 5.7 9.3 6.5 5.9 1.1 5.4 8.5 10.5 4.5 5.6 5.4 9.9 9.4 5.4 4.4 3.2 7.0 3.6 6.7 6.5 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687365 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 34.8" "Cell type enhanced" "Detected in some" "NK-cell: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA058210: , HPA067385: " "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavourable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.1 3.4 6.7 10.2 4.4 29.3 6.2 34.8 14.4 7.0 6.6 2.0 7.6 7.3 6.1 4.4 7.5 6.2 6.5 4.7 5.6 1.6 3.8 8.6 5.4 8.2 3.3 4.3 8.7 6.8 3.6 3.1 6.5 5.1 6.8 7.7 4.3 8.7 7.4 8.9 17.9 8.5 6.8 3.7 16.7 7.8 25.6 4.4 29.8 5.1 6.0 10.3 6.7 8.7 0.5 1.7 0.8 0.8 4.8 0.7 0.5 11.1 14.9 22.1 10.6 4.7 3.6 19.7 11.4 5.2 13.7 10.0 18.0 6.6 12.8 4.8 6.2 15.5 15.4 7.7 8.4 5.9 19.5 20.2 19.2 8.8 0.9 15.8 11.6 2.8 3.0 14.2 4.7 4.8 22.6 7.2 6.7 18.1 25.9 28.9 17.2 8.9 21.5 12.5 5.8 4.3 18.3 18.5 10.6 13.3 10.9 2.5 16.1 9.8 4.3 12.5 12.8 9.4 11.5 9.6 6.5 20.1 6.8 21.9 8.8 0.0 0.3 0.8 0.5 0.1 0.7 0.5 0.3 0.4 0.7 0.3 0.5 0.3 0.1 4.8 0.8 1.7 0.6 0.5 6.7 4.4 34.8 14.4 5.6 1.6 3.3 4.3 5.1 4.4 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.6;lymphoid tissue: 17.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 3.3 2.2 1.5 11.6 2.8 17.6 3.4 1.7 1.6 4.4 4.2 1.1 1.5 2.6 2.8 3.5 9.0 2.4 2.3 1.6 1.0 1.2 2.5 5.1 2.2 5.3 1.1 0.3 2.7 5.0 1.4 2.5 4.1 1.4 2.1 5.2 2.6 2.6 0.7 1.1 3.7 7.7 2.9 2.7 5.4 3.0 5.3 2.4 17.6 1.6 10.3 8.4 2.1 4.2 1.2 0.9 0.7 0.0 3.2 2.7 0.5 17.1 8.8 16.7 7.7 0.8 4.9 8.5 9.8 5.0 15.6 18.1 8.8 13.5 10.7 5.6 5.5 10.6 16.7 6.0 18.5 12.5 9.2 15.9 9.7 10.9 0.4 18.9 6.9 1.4 0.4 8.5 1.4 9.0 13.9 6.9 15.6 15.0 19.2 12.4 9.8 20.6 16.4 15.4 9.7 5.6 9.7 12.0 6.9 9.9 5.8 3.1 11.7 6.7 3.2 2.5 18.6 10.4 7.7 5.0 10.2 24.7 4.7 14.0 10.0 0.0 0.0 0.7 0.9 0.0 0.7 1.2 0.9 1.7 0.6 1.2 0.1 0.8 0.0 3.2 0.0 0.9 2.7 0.5 1.5 2.8 1.7 1.6 1.0 1.2 1.1 0.3 1.4 2.4 POLE3 "CHARAC17, CHRAC17, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410672 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047945 Uncertain Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA047945: " "unprognostic (9.55e-2)" "unprognostic (3.39e-3)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.86e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (1.04e-2)" "unprognostic (1.60e-2)" "unprognostic (1.10e-1)" "unprognostic (4.59e-3)" "unprognostic (2.31e-3)" "unprognostic (1.75e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" 16.9 23.9 18.2 22.0 18.5 56.3 19.3 36.0 25.0 17.0 17.6 15.8 12.5 15.1 18.2 16.5 27.8 17.6 17.0 17.9 16.1 14.8 14.3 29.5 15.8 29.0 15.1 18.5 15.4 20.8 13.1 8.4 21.2 20.0 15.9 20.3 12.4 17.9 16.3 48.3 24.7 17.3 16.9 16.9 26.8 17.2 29.9 15.9 35.0 16.3 27.3 32.4 18.8 16.7 34.9 33.5 34.3 34.4 28.0 44.0 47.7 15.7 19.7 13.9 20.8 7.9 7.1 12.2 21.1 10.8 23.9 18.9 18.2 14.4 57.4 13.1 12.3 27.1 27.0 23.2 22.1 10.9 16.3 29.8 20.4 18.6 8.5 61.7 18.0 8.1 16.0 20.7 26.8 16.5 41.5 32.1 16.6 40.1 42.3 33.2 17.9 35.7 43.4 57.9 32.2 10.4 15.1 30.1 17.4 30.6 19.4 16.5 29.0 27.8 13.6 17.8 24.1 22.4 36.0 16.8 54.9 77.4 16.2 36.5 21.2 25.4 34.0 34.3 35.5 34.4 44.0 34.9 34.0 33.7 33.2 33.5 36.9 34.3 7.2 28.0 26.6 33.5 39.0 47.7 18.2 18.5 36.0 25.0 16.1 14.8 15.1 18.5 20.0 15.9 POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958492-74970128 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054979, HPA071815" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA054979: , HPA071815: " "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (3.09e-1)" "unprognostic (1.99e-1)" "unprognostic (2.95e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (8.64e-3)" "unprognostic (6.61e-2)" "unprognostic (3.73e-1)" "unprognostic (3.47e-2)" "unprognostic (1.95e-1)" 19.2 14.5 23.6 15.2 17.3 27.1 21.4 4.4 15.5 18.4 13.4 8.6 7.0 9.0 10.4 9.0 10.0 9.7 13.1 18.1 15.9 10.6 11.6 18.8 10.7 17.0 13.9 12.6 12.8 12.5 2.8 3.9 9.6 12.2 12.0 8.8 13.9 16.2 11.2 28.1 8.1 12.4 14.1 11.7 12.2 12.5 11.0 10.0 5.5 13.1 15.1 10.4 13.9 31.9 14.7 14.7 8.0 22.2 4.4 9.9 12.3 11.7 11.2 1.0 1.0 3.8 8.6 0.0 8.0 9.9 12.8 10.9 14.9 5.2 11.5 6.7 9.0 5.3 5.3 6.6 15.0 5.2 14.4 8.9 6.5 14.7 13.9 12.6 14.1 8.7 13.0 5.3 11.8 5.5 10.9 6.8 9.7 11.4 3.7 35.6 7.8 21.1 4.5 9.6 9.3 10.6 0.3 3.5 5.3 11.0 4.6 6.3 3.4 4.1 6.2 2.9 3.3 2.0 7.6 2.4 1.6 4.2 10.5 18.9 14.1 2.3 22.2 8.0 6.3 13.2 7.0 14.7 8.9 7.8 12.9 13.7 9.9 6.9 1.6 4.4 12.4 14.7 8.5 12.3 23.6 17.3 4.4 15.5 15.9 10.6 13.9 12.6 12.2 10.0 POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease mutation, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria Mitochondria "HPA056821: , HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" 17.8 15.2 19.8 19.0 19.2 16.8 24.6 23.2 20.9 14.1 16.0 14.6 13.6 20.0 17.6 9.0 20.7 14.3 14.0 17.4 16.7 8.8 14.9 19.5 17.8 21.8 17.3 15.3 16.6 17.9 17.7 12.9 16.2 16.0 15.4 13.2 10.5 15.9 12.0 35.9 19.8 18.5 14.1 12.7 22.9 16.2 12.4 17.3 29.0 15.4 12.1 19.2 16.5 18.9 6.0 9.0 9.0 6.5 9.2 10.9 6.7 6.8 13.0 9.0 11.7 14.7 9.4 11.5 13.7 7.3 14.1 11.1 19.0 17.2 10.8 21.2 10.8 14.9 24.0 11.6 4.7 23.3 20.6 16.4 13.7 6.8 12.5 15.2 27.1 8.5 17.0 9.7 8.3 16.8 14.4 12.2 11.4 12.1 17.3 15.5 8.1 5.8 17.7 11.0 15.3 8.0 16.8 20.0 7.3 19.5 14.3 15.9 11.9 17.1 12.5 19.1 13.2 28.0 13.1 13.1 7.6 15.0 12.2 17.5 15.2 4.9 6.3 9.0 9.2 6.5 8.0 3.3 7.6 10.9 9.0 6.0 6.6 6.9 2.3 9.2 5.2 6.0 4.3 6.7 19.8 19.2 23.2 20.9 16.7 8.8 17.3 15.3 16.0 17.3 POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497036 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017030, HPA023202" Approved Approved "Nuclear bodies,Mitochondria" "Nuclear bodies" Mitochondria "CAB017030: , HPA023202: AB_1855523" "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavourable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavourable (6.59e-4)" "prognostic unfavourable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" 6.7 9.3 5.4 17.5 10.0 8.1 8.2 10.9 8.7 7.7 7.8 7.0 11.1 7.9 10.2 6.8 6.4 7.5 7.9 7.3 5.6 4.4 7.8 7.8 10.4 12.2 10.8 5.2 13.0 9.4 5.0 9.9 6.9 8.7 8.0 5.7 5.8 8.6 11.9 10.7 10.5 8.4 9.3 5.6 11.5 6.9 24.2 7.9 9.8 9.6 5.4 13.3 6.6 11.5 12.2 10.5 6.5 8.2 6.0 12.2 4.4 6.7 8.3 6.0 7.4 5.7 4.6 7.3 4.0 3.8 6.1 5.3 8.6 5.4 12.4 4.9 2.1 5.6 8.2 3.8 7.7 3.5 9.4 8.4 10.0 8.5 6.4 11.9 9.4 4.6 4.4 4.9 7.3 4.4 14.7 4.8 5.9 9.0 12.6 15.7 6.3 9.3 11.8 19.6 13.1 5.6 2.0 8.4 9.4 3.2 7.3 7.4 7.1 10.0 4.9 6.6 8.9 5.7 10.4 8.5 5.7 9.4 5.2 11.1 4.6 6.5 5.9 6.5 7.9 3.5 7.5 12.2 8.8 7.6 10.5 12.1 12.2 11.6 1.2 6.0 8.2 4.8 8.4 4.4 5.4 10.0 10.9 8.7 5.6 4.4 10.8 5.2 8.7 7.9 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576150-43615660 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease mutation, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 7.4 9.4 7.5 9.7 10.4 4.6 7.2 10.5 10.5 8.5 8.4 12.7 8.0 5.7 9.6 7.1 11.4 7.8 6.2 6.7 5.3 4.4 7.2 7.5 9.8 16.3 8.9 8.1 7.4 13.0 7.1 9.7 5.1 7.9 6.9 10.1 8.9 8.6 5.6 9.5 11.7 7.9 11.8 6.9 9.2 7.6 24.7 6.8 22.1 9.9 6.2 18.3 8.6 8.4 8.6 4.3 4.5 2.6 6.8 7.2 3.2 20.2 4.7 6.3 9.2 9.0 14.9 15.0 21.7 6.8 12.7 14.7 5.3 3.6 22.5 5.5 8.8 5.1 6.4 13.7 15.8 11.3 4.9 6.6 13.1 15.4 6.7 11.2 8.9 10.0 16.7 10.4 5.6 12.0 10.4 13.5 16.0 6.7 10.2 2.9 1.9 3.5 11.2 6.5 5.6 4.8 15.2 7.1 2.4 6.9 5.8 3.4 8.2 5.0 16.2 11.8 11.4 5.5 10.9 12.7 8.8 40.6 5.6 6.6 12.8 4.5 2.6 4.1 7.2 2.5 6.4 7.8 6.0 5.2 2.1 8.6 5.0 5.2 2.0 6.8 1.9 4.3 7.0 3.2 7.5 10.4 10.5 10.5 5.3 4.4 8.9 8.1 7.9 6.8 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269404-54321266 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: " "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 16.5 11.1 10.2 9.5 14.0 5.2 15.8 9.6 14.7 12.9 9.9 13.4 13.7 6.6 13.2 13.1 6.6 10.3 8.3 9.1 8.7 7.6 12.9 6.4 9.0 7.4 10.9 9.0 16.4 11.8 17.6 21.3 17.4 15.3 12.7 7.7 9.6 11.3 14.7 7.2 8.2 7.6 10.9 12.0 8.2 9.0 30.5 10.9 17.3 27.3 1.5 7.0 12.7 10.5 9.9 10.3 10.9 10.7 7.9 12.7 7.1 7.7 2.8 21.3 12.9 7.2 14.1 6.9 6.4 13.8 7.4 12.4 2.1 7.4 3.7 2.1 9.3 6.4 5.0 7.3 8.3 8.8 2.5 4.6 3.2 5.4 11.8 7.3 3.8 15.2 11.2 6.4 13.4 15.6 3.1 10.5 12.3 6.1 5.2 6.4 7.3 3.1 3.3 4.3 9.1 8.4 10.3 10.0 10.2 4.6 4.1 6.8 14.8 3.3 7.5 13.9 3.8 2.1 5.3 8.5 1.9 5.2 9.9 6.6 10.1 5.4 10.7 10.9 8.3 5.7 7.7 8.6 8.8 8.6 10.3 9.9 12.7 7.6 6.7 7.9 5.8 8.1 9.8 7.1 10.2 14.0 9.6 14.7 8.7 7.6 10.9 9.0 15.3 10.9 POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511756-75601144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA012035: , HPA057303: , HPA068117: , HPA069375: " "unprognostic (9.66e-2)" "unprognostic (5.29e-2)" "unprognostic (5.37e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.65e-2)" "unprognostic (6.29e-3)" "unprognostic (2.42e-1)" "unprognostic (5.93e-2)" "unprognostic (1.80e-2)" "unprognostic (9.96e-3)" "unprognostic (1.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.02e-1)" 14.7 12.7 10.1 8.6 12.9 6.3 13.4 17.0 13.4 18.1 10.7 8.8 13.6 6.3 21.3 12.1 11.7 10.5 9.5 11.4 14.1 10.5 12.6 12.3 12.2 9.2 14.1 12.9 15.5 11.1 18.5 23.9 15.2 17.2 13.9 8.1 6.5 10.2 10.5 15.2 10.3 9.2 15.4 16.9 13.1 9.0 9.8 12.4 12.1 18.8 9.3 8.9 12.7 10.2 7.0 7.5 6.0 13.3 4.6 4.5 2.5 6.4 6.6 4.1 5.2 5.4 10.9 3.5 12.3 8.7 9.6 10.0 4.2 5.2 6.6 10.1 8.1 2.5 3.8 4.2 11.5 7.3 4.4 6.0 5.8 1.9 10.4 3.8 4.9 5.0 5.2 7.7 5.3 8.0 5.3 3.9 9.0 0.5 7.5 3.1 1.5 3.9 3.2 10.5 4.6 5.8 2.2 4.2 4.6 9.2 2.5 3.3 3.6 3.7 10.0 7.0 3.6 3.3 7.0 4.5 4.1 5.9 4.7 6.1 12.0 5.7 7.1 3.4 3.3 7.9 2.9 7.0 3.7 4.0 6.1 5.4 4.5 3.0 6.0 4.6 13.3 7.5 4.1 2.5 10.1 12.9 17.0 13.4 14.1 10.5 14.1 12.9 17.2 12.4 POLL ENSG00000166169 "DNA polymerase lambda" Q9UGP5 10 101578882-101588270 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066704 Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" "Nucleoplasm, Golgi apparatus" "HPA066704: " "unprognostic (3.71e-3)" "unprognostic (6.93e-3)" "unprognostic (1.73e-2)" "unprognostic (2.47e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-2)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" "unprognostic (8.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.12e-2)" "unprognostic (7.19e-2)" "unprognostic (4.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" "unprognostic (1.64e-3)" 11.0 15.1 14.4 16.0 17.1 9.2 13.4 11.2 22.1 13.7 12.6 16.4 15.6 14.3 15.1 22.1 15.4 18.1 17.7 12.3 11.1 10.4 16.4 16.5 11.8 13.0 9.6 13.0 20.9 30.7 21.7 23.7 11.7 12.7 17.2 15.0 19.5 17.8 14.7 26.1 12.8 11.9 12.7 9.4 15.6 16.7 53.2 11.2 4.6 18.3 10.2 14.2 14.8 11.6 8.5 10.7 1.1 8.5 8.4 11.9 7.1 12.5 11.5 9.1 12.6 9.2 17.2 12.7 8.3 14.5 12.8 13.5 8.4 15.2 3.1 13.2 7.5 15.8 10.0 12.3 10.3 11.1 13.6 9.8 10.8 9.5 17.0 10.2 9.0 15.6 16.8 14.1 29.4 13.7 10.9 10.9 8.0 10.0 0.0 11.2 4.8 6.8 0.0 8.1 5.1 10.7 7.6 6.4 9.3 5.1 8.6 14.3 26.2 5.9 7.3 4.6 9.3 5.2 9.1 15.8 7.9 4.7 9.9 8.9 3.4 0.5 8.5 1.1 6.7 5.9 10.6 8.5 7.4 6.8 10.7 7.1 11.9 7.9 0.9 8.4 5.7 0.2 8.9 7.1 14.4 17.1 11.2 22.1 11.1 10.4 9.6 13.0 12.7 11.2 POLM Tdt-N ENSG00000122678 "DNA polymerase mu" Q9NP87 7 44072247-44082540 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 31.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058900, HPA066007" Supported Nucleoplasm Nucleoplasm "HPA058900: , HPA066007: " "unprognostic (2.44e-2)" "unprognostic (8.18e-2)" "unprognostic (2.21e-3)" "unprognostic (3.93e-2)" "unprognostic (5.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (3.91e-1)" "unprognostic (9.36e-2)" "unprognostic (8.26e-2)" "unprognostic (2.46e-3)" "unprognostic (6.31e-2)" "unprognostic (1.47e-1)" "unprognostic (2.87e-1)" "unprognostic (3.87e-3)" 10.7 8.7 7.0 18.0 7.1 7.6 12.2 11.9 8.8 13.8 11.2 11.1 11.7 12.2 10.1 12.0 11.7 11.8 11.8 10.8 6.8 4.4 13.0 12.5 10.1 20.9 9.9 7.0 13.8 12.3 10.0 9.0 8.1 8.2 11.8 7.1 12.4 13.5 14.3 11.2 12.0 12.6 8.9 9.0 18.7 12.0 6.8 8.1 30.1 15.4 8.3 17.6 12.4 10.7 5.9 4.8 31.6 2.1 3.5 4.2 1.3 1.0 1.5 1.5 3.4 2.2 2.5 4.9 3.5 3.9 2.7 1.6 1.9 2.6 11.1 3.5 2.9 3.3 1.6 37.7 1.5 3.9 3.5 1.3 1.6 0.7 3.1 3.4 5.0 4.0 3.6 2.2 2.8 4.8 1.6 5.4 2.3 2.5 7.0 3.0 3.3 8.1 5.6 0.9 4.4 3.0 1.8 1.6 2.9 1.7 7.2 3.6 4.6 6.0 3.3 1.9 2.8 1.9 5.1 8.9 4.4 8.7 3.5 3.1 4.6 8.6 1.8 5.1 3.3 2.1 3.3 4.0 2.9 3.0 1.6 5.9 4.2 3.4 31.6 3.5 1.6 4.8 2.7 1.3 7.0 7.1 11.9 8.8 6.8 4.4 9.9 7.0 8.2 8.1 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 5.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "eosinophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035939, HPA035940" Enhanced Nucleoplasm Nucleoplasm "HPA035939: , HPA035940: " "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 13.6 3.9 6.1 2.5 5.7 1.8 5.2 11.1 5.5 2.8 2.9 3.5 2.9 2.7 4.0 5.8 2.6 3.6 3.3 2.8 4.4 2.9 3.6 3.4 3.0 2.7 4.3 4.0 2.8 3.1 2.4 7.6 2.3 3.8 4.6 1.8 1.7 4.7 3.5 2.7 2.7 2.4 3.3 5.6 3.5 2.9 12.3 5.2 8.5 2.4 0.9 2.6 2.5 2.6 0.2 0.1 2.4 0.0 0.0 0.9 0.1 0.3 2.7 0.5 1.9 5.7 2.2 0.0 1.9 1.0 1.1 1.6 0.1 0.2 1.2 0.5 1.7 0.4 2.2 0.8 1.6 0.3 2.9 0.1 1.9 0.0 0.7 0.2 2.5 3.0 0.8 1.6 1.4 0.6 0.2 2.3 3.1 0.3 0.2 0.2 0.2 0.5 0.0 3.8 0.9 0.8 0.5 2.5 0.0 0.2 0.0 0.2 0.0 0.7 0.3 0.1 1.9 1.1 0.6 0.6 0.7 0.0 0.6 1.8 1.1 0.0 0.0 2.4 0.2 0.0 0.9 0.2 0.2 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.1 6.1 5.7 11.1 5.5 4.4 2.9 4.3 4.0 3.8 5.2 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.5;lymphoid tissue: 21.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.2" "HPA048931, HPA053359" Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA048931: , HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavourable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favourable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.5 0.8 0.2 8.2 0.7 9.5 0.6 0.6 0.4 0.9 3.5 0.2 0.8 2.0 0.9 0.6 6.0 0.3 0.4 0.8 0.3 0.2 0.4 0.6 0.9 4.7 0.3 0.0 0.4 0.4 0.0 0.2 2.8 0.3 0.4 3.7 0.1 1.1 0.8 1.2 2.4 3.9 0.5 0.4 2.6 1.1 5.8 0.6 21.4 0.3 5.6 7.5 0.6 1.7 0.5 1.1 1.6 0.4 0.0 0.4 0.0 13.3 9.1 7.8 5.5 0.7 0.9 7.1 6.3 2.4 7.5 10.1 7.2 5.0 15.9 2.9 3.4 10.6 9.2 4.1 12.8 4.6 5.0 10.2 5.6 4.5 0.0 11.0 9.3 0.1 0.3 6.8 4.2 3.7 6.7 12.1 7.8 5.2 9.9 6.4 7.4 4.4 8.4 9.4 5.6 2.4 7.7 4.3 3.8 7.3 4.0 2.6 3.7 10.9 2.8 6.6 8.7 2.6 8.2 6.1 4.9 16.5 3.2 8.2 4.9 1.6 0.2 0.0 0.3 0.2 0.0 0.3 0.4 0.3 0.4 0.5 0.0 0.2 0.0 0.0 0.4 1.1 0.1 0.0 0.2 0.7 0.6 0.4 0.3 0.2 0.3 0.0 0.3 0.6 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: , HPA049700: " "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavourable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavourable (8.41e-4)" "unprognostic (7.20e-2)" 14.3 12.9 10.1 12.4 16.5 9.7 10.3 12.2 20.3 11.1 11.0 17.4 8.3 9.4 19.5 7.4 13.5 12.3 11.7 12.7 9.0 9.2 11.5 15.1 9.4 9.6 9.0 9.4 12.6 14.3 18.2 15.9 11.4 13.8 10.7 11.8 13.9 11.2 12.5 22.5 12.3 8.6 16.0 8.0 11.2 10.4 14.9 10.9 14.0 10.3 11.4 14.2 10.9 9.6 2.6 2.6 1.8 2.5 2.0 3.8 1.2 9.3 21.3 9.5 18.3 9.3 7.5 13.8 8.6 5.7 12.4 7.7 26.7 7.4 21.5 9.2 8.8 10.9 24.5 12.7 11.1 8.9 12.6 18.5 9.1 17.9 6.6 17.5 10.0 5.7 8.0 18.4 14.4 9.6 24.5 5.4 8.5 8.3 12.9 7.5 17.3 14.1 15.6 20.9 10.0 5.5 15.4 14.8 7.7 9.5 12.6 6.8 7.4 6.1 15.2 15.1 11.9 12.8 17.3 7.7 7.4 18.8 7.8 15.1 13.3 1.8 1.5 0.2 3.0 2.5 3.8 2.0 1.5 2.5 1.8 2.6 1.4 1.8 0.7 2.0 1.9 2.6 0.7 1.2 10.1 16.5 12.2 20.3 9.0 9.2 9.0 9.4 13.8 10.9 POLR1B "FLJ10816, FLJ21921, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112577150 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA037528: AB_10671627" "unprognostic (1.66e-1)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (2.71e-5)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (6.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" 8.8 11.0 6.4 10.6 6.8 4.9 15.7 8.0 8.2 7.6 7.0 7.7 8.6 5.8 9.3 7.4 12.8 9.2 9.2 6.1 5.7 6.1 11.3 20.5 8.0 11.3 6.8 3.7 11.3 25.2 20.7 11.5 7.2 5.2 7.7 8.5 7.3 10.0 8.3 14.7 9.2 8.0 7.9 4.8 11.4 8.1 15.7 5.0 9.6 15.7 11.5 14.6 8.9 11.8 9.4 11.0 2.5 6.3 10.2 17.1 7.3 9.4 9.9 6.3 13.0 6.8 6.6 11.8 7.1 5.4 12.0 10.5 22.2 5.6 22.7 10.6 4.7 13.3 26.4 14.5 13.9 10.2 13.3 13.1 9.9 16.7 7.2 20.9 9.1 6.2 10.5 12.5 19.3 9.3 23.7 8.2 6.3 8.3 9.4 13.6 30.6 19.7 14.2 10.4 24.1 8.3 9.0 15.9 14.8 6.5 16.5 9.0 7.6 7.4 8.4 7.4 10.9 6.8 10.4 11.1 18.3 19.6 5.6 13.4 6.2 0.2 6.0 2.5 8.3 6.3 17.1 9.4 8.4 8.9 11.0 9.3 10.3 10.4 0.4 10.2 4.8 2.6 11.3 7.3 6.4 6.8 8.0 8.2 5.7 6.1 6.8 3.7 5.2 5.0 POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" P24928 17 7484366-7514616 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription" "DNA-binding, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEK 293: 3.0;HL-60: 2.6;HMC-1: 3.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.9" "CAB012226, CAB016388, CAB022311" Enhanced Approved Nucleoplasm Nucleoplasm "CAB012226: AB_304749, CAB016388: AB_677353, CAB022311: " "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-2)" "unprognostic (8.77e-3)" "unprognostic (1.48e-1)" "unprognostic (5.19e-3)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" 5.0 5.9 4.5 5.7 7.4 26.4 8.5 5.8 7.8 7.2 4.3 4.8 4.5 4.3 5.5 5.4 7.0 4.6 4.2 4.5 6.0 3.5 4.6 4.4 6.4 11.5 4.7 4.2 5.2 5.8 5.4 4.8 4.2 5.4 4.3 4.9 6.3 5.5 8.1 6.6 6.6 6.0 4.5 6.1 6.2 5.3 13.2 2.9 15.0 5.6 4.1 5.0 5.3 4.6 0.7 0.7 4.9 1.0 0.0 1.2 0.0 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.5 0.0 0.2 0.0 0.2 0.4 3.0 0.7 1.2 0.2 0.0 2.6 3.9 0.4 0.0 0.3 0.0 0.2 0.3 0.0 0.5 0.0 0.1 0.8 0.4 0.9 1.1 0.0 0.0 0.0 1.4 0.3 0.9 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.5 0.8 0.4 0.2 0.4 0.0 0.6 0.3 3.0 0.5 0.6 1.2 0.4 0.3 0.3 0.5 0.4 0.1 0.7 0.6 0.5 4.9 0.0 1.0 0.7 0.5 0.0 4.5 7.4 5.8 7.8 6.0 3.5 4.7 4.2 5.4 2.9 POLR2B RPB2 ENSG00000047315 "RNA polymerase II subunit B" P30876 4 56977722-57031168 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037506 Supported Supported Nucleoplasm Nucleoplasm "HPA037506: AB_10672597" "unprognostic (9.88e-3)" "unprognostic (4.38e-2)" "unprognostic (1.83e-3)" "unprognostic (7.51e-2)" "unprognostic (2.30e-2)" "unprognostic (4.21e-3)" "unprognostic (1.24e-3)" "unprognostic (3.51e-1)" "unprognostic (6.39e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "prognostic favourable (7.17e-4)" "unprognostic (1.91e-1)" "unprognostic (1.51e-1)" "unprognostic (3.43e-1)" "unprognostic (7.35e-2)" 24.5 34.3 31.1 34.6 31.0 21.4 24.8 43.8 33.3 25.9 26.0 18.8 24.9 22.5 35.1 21.4 27.4 28.3 21.2 32.9 29.3 21.7 26.2 21.4 21.2 32.4 28.0 30.2 26.4 28.1 40.7 37.3 25.4 28.3 24.8 26.5 18.4 30.5 28.2 61.8 24.4 27.3 27.6 26.4 27.1 28.8 26.6 26.8 33.4 27.0 34.7 35.1 31.5 22.4 19.8 15.2 27.8 13.9 18.0 23.8 12.7 24.7 20.7 37.4 31.6 30.9 27.9 20.0 33.0 33.6 33.1 31.0 26.3 25.0 38.6 31.3 30.5 17.6 44.9 25.1 47.4 18.3 20.1 29.0 23.1 22.9 35.8 49.9 33.6 30.0 25.3 37.8 23.1 39.4 43.1 33.0 38.1 18.1 47.0 19.3 30.8 24.3 34.3 24.6 21.2 22.6 28.2 31.2 35.0 20.5 39.1 28.4 21.0 27.8 28.7 24.1 32.4 25.2 43.3 26.6 25.3 56.3 27.5 27.0 29.8 27.8 12.2 16.8 20.7 12.4 22.0 19.8 20.3 21.4 15.2 14.4 19.9 23.8 11.3 18.0 13.9 12.9 20.9 12.7 31.1 31.0 43.8 33.3 29.3 21.7 28.0 30.2 28.3 26.8 POLR3A "hRPC155, RPC1, RPC155" ENSG00000148606 "RNA polymerase III subunit A" O14802 10 77969251-78029545 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037926 Uncertain Supported Nucleoplasm Nucleoplasm "HPA037926: AB_10672400" "unprognostic (6.83e-2)" "unprognostic (3.41e-2)" "unprognostic (4.54e-2)" "unprognostic (2.76e-2)" "unprognostic (6.41e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (3.64e-6)" "unprognostic (3.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (6.64e-2)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (3.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.11e-2)" 7.1 10.2 10.3 8.3 21.7 5.9 10.6 22.2 29.7 9.2 8.1 12.8 7.4 8.6 9.4 13.3 8.6 8.5 7.4 7.4 9.4 9.6 9.3 9.3 6.8 8.7 8.1 11.0 11.5 10.7 13.8 17.3 10.1 20.4 10.2 10.7 10.4 8.6 8.2 17.6 11.2 7.8 9.7 6.6 8.9 8.2 11.7 9.8 12.6 9.6 4.4 13.4 7.9 8.0 7.5 5.4 8.0 6.4 6.5 8.8 3.6 7.3 8.8 9.3 15.4 6.1 7.9 6.2 8.4 11.0 10.9 10.8 11.5 5.3 9.1 5.2 7.3 8.6 16.1 9.2 13.3 6.7 11.8 7.3 7.0 14.2 5.8 12.5 6.2 6.7 6.6 19.3 18.0 9.5 13.6 5.7 10.5 5.4 9.4 8.0 10.1 40.0 9.0 5.9 5.9 5.4 4.8 8.5 10.8 8.1 15.1 8.6 11.2 6.6 10.4 7.0 6.8 7.6 16.6 8.9 9.3 11.1 12.5 13.2 3.4 8.0 5.2 2.9 7.8 6.4 7.6 5.6 6.0 7.2 4.8 7.5 5.7 6.6 3.3 6.5 5.4 5.4 8.8 3.6 10.3 21.7 22.2 29.7 9.4 9.6 8.1 11.0 20.4 9.8 POLR3B "FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357658-106510198 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favourable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 6.4 14.0 7.1 7.9 14.6 6.5 6.9 8.6 13.6 8.6 7.2 8.2 5.7 6.0 10.1 7.2 14.8 7.7 5.8 8.2 8.9 7.1 9.9 17.5 7.1 11.4 6.2 10.4 11.3 11.9 22.5 17.0 22.9 12.3 8.0 8.3 6.2 8.6 9.9 12.1 15.3 5.7 7.8 6.0 6.4 7.5 9.9 4.7 10.3 8.5 10.2 10.0 7.3 10.1 4.3 4.9 9.8 4.1 3.7 6.3 3.1 11.1 5.3 11.8 5.6 10.5 9.6 16.4 15.7 9.5 10.9 8.5 9.7 3.1 14.2 5.6 9.7 10.4 13.6 13.4 13.6 11.5 9.1 11.3 7.1 8.2 6.7 17.9 12.3 8.5 9.6 10.9 12.7 8.1 16.6 4.7 8.3 8.2 13.0 6.0 12.7 19.9 7.9 7.0 9.3 6.2 15.2 12.8 7.0 9.6 12.9 9.2 12.0 5.3 7.7 6.0 7.1 9.7 9.0 5.8 14.8 21.2 2.9 11.1 6.4 9.8 3.9 2.6 4.1 4.1 5.5 4.3 4.5 4.3 4.9 2.6 6.3 3.9 2.6 3.7 4.0 1.8 4.7 3.1 7.1 14.6 8.6 13.6 8.9 7.1 6.2 10.4 12.3 4.7 POLRMT "APOLMT, h-mtRPOL, MTRNAP, MTRPOL" ENSG00000099821 "RNA polymerase mitochondrial" O00411 19 617224-633604 "Enzymes, Predicted intracellular proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006366 Uncertain Supported Mitochondria Mitochondria "HPA006366: AB_1079654" "unprognostic (3.24e-1)" "unprognostic (4.31e-2)" "unprognostic (7.96e-2)" "prognostic favourable (4.50e-4)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (3.04e-2)" "unprognostic (9.41e-2)" "unprognostic (1.45e-1)" "unprognostic (3.48e-1)" "unprognostic (7.64e-3)" "unprognostic (1.81e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-3)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" 10.2 10.7 10.1 16.3 11.9 6.9 8.1 12.1 20.7 9.5 11.6 12.3 4.4 16.7 9.8 12.2 14.4 8.7 12.7 24.7 11.5 8.9 12.9 21.4 7.3 11.8 9.4 15.1 10.1 15.9 9.5 10.7 6.2 9.7 10.2 8.8 8.5 9.6 11.7 42.2 16.7 12.8 10.8 8.4 12.8 11.2 32.1 6.3 11.6 11.1 8.6 10.4 10.1 7.8 8.2 7.3 3.1 5.5 7.5 9.0 5.3 10.4 19.0 4.3 19.1 9.1 5.2 16.0 4.9 5.8 7.3 6.7 19.1 7.2 10.8 10.0 4.5 10.9 16.1 9.4 5.4 12.1 38.3 8.4 11.8 24.5 9.5 14.1 16.0 5.0 13.3 7.4 9.1 10.3 15.7 10.8 6.7 14.8 18.7 19.4 17.3 13.4 18.1 6.0 18.4 9.7 9.0 14.0 9.9 4.4 12.2 12.2 6.9 12.9 6.1 7.9 10.2 12.4 14.4 25.8 21.2 16.5 17.0 11.8 9.7 0.0 3.7 3.1 9.0 5.2 7.1 7.8 6.7 6.6 7.3 8.2 5.7 6.3 0.6 7.5 5.5 7.2 4.1 5.3 10.1 11.9 12.1 20.7 11.5 8.9 9.4 15.1 9.7 6.3 POMGNT2 "AGO61, C3orf39, FLJ14566, GTDC2" ENSG00000144647 "Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)" Q8NAT1 3 43079232-43106076 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034870, HPA040989" Uncertain "Intracellular and membrane" "HPA034870: AB_10602701, HPA040989: " "unprognostic (2.37e-3)" "unprognostic (8.22e-2)" "prognostic favourable (8.13e-5)" "unprognostic (2.57e-2)" "unprognostic (4.17e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.26e-5)" "unprognostic (8.71e-2)" "unprognostic (1.73e-2)" "unprognostic (7.43e-2)" "unprognostic (1.95e-2)" "unprognostic (4.01e-1)" "prognostic favourable (4.00e-7)" "unprognostic (4.98e-2)" "unprognostic (1.55e-1)" "unprognostic (3.26e-1)" "unprognostic (2.57e-1)" 8.4 12.7 13.9 4.1 20.2 16.6 6.8 28.4 32.7 14.2 7.1 13.1 6.2 3.8 28.2 12.0 7.9 21.7 10.3 15.6 12.5 13.2 7.8 6.8 7.3 2.9 10.6 12.3 21.1 14.7 14.0 10.6 5.6 13.5 10.6 3.2 11.1 13.5 15.8 15.0 7.2 4.1 20.1 7.3 4.4 7.4 9.1 8.8 4.4 10.6 3.4 3.4 7.6 7.6 2.9 1.2 1.0 0.9 1.6 5.7 1.8 11.4 8.8 5.1 15.5 19.7 5.1 8.1 3.3 6.0 11.8 13.9 10.6 8.1 0.0 12.5 6.0 0.2 8.3 9.6 5.2 0.0 23.3 8.1 7.0 10.1 7.5 5.6 9.7 5.9 7.1 7.9 4.7 4.5 6.6 0.0 4.6 6.8 10.2 1.5 11.2 16.5 4.0 3.6 7.2 6.9 8.4 8.1 7.4 6.9 5.6 6.3 10.7 5.0 2.1 9.6 13.5 14.0 13.5 8.7 13.0 0.1 12.3 11.4 10.1 0.0 0.9 1.0 5.7 0.8 5.1 2.9 3.8 3.8 1.1 1.9 4.9 3.8 0.0 1.6 0.8 1.2 2.9 1.8 13.9 20.2 28.4 32.7 12.5 13.2 10.6 12.3 13.5 8.8 POMK "FLJ23356, SgK196" ENSG00000185900 "Protein-O-mannose kinase" Q9H5K3 8 43093506-43123434 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA013321: AB_2668809" "unprognostic (1.66e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (4.37e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.10e-2)" 4.7 5.5 9.8 5.6 14.3 12.5 5.1 12.3 18.6 6.9 4.8 8.3 2.2 4.5 6.9 4.4 7.1 6.2 4.8 3.8 7.7 7.0 3.4 4.5 5.5 6.0 4.8 11.1 5.8 9.3 6.3 7.4 6.1 10.5 5.6 5.9 6.1 6.8 4.0 6.2 7.1 5.6 6.4 6.7 7.6 6.8 7.1 7.2 7.5 7.4 3.2 7.4 4.6 5.0 2.6 2.6 6.7 2.9 1.0 3.3 1.3 3.5 7.5 5.8 15.1 2.8 3.4 5.5 2.1 3.1 5.5 4.0 5.5 9.1 4.9 4.6 3.8 5.8 8.2 6.3 5.3 1.9 1.4 13.9 5.5 2.4 2.0 4.7 7.8 3.8 2.7 7.3 5.3 5.4 3.2 14.8 3.7 1.6 9.9 2.0 11.8 1.0 6.8 6.8 2.8 1.5 9.8 5.6 4.1 9.1 3.1 3.0 9.7 3.2 7.4 8.4 8.4 8.6 4.2 4.8 8.5 9.3 3.5 3.2 9.9 0.8 2.9 1.9 2.3 2.4 3.3 1.8 1.3 1.3 2.6 2.6 1.8 2.3 6.7 1.0 1.5 2.5 1.1 1.3 9.8 14.3 12.3 18.6 7.7 7.0 4.8 11.1 10.5 7.2 POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502902-131523806 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065252 Approved "Golgi apparatus" "Golgi apparatus" "HPA065252: " "unprognostic (2.00e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (5.09e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (5.35e-3)" "unprognostic (1.14e-1)" "unprognostic (9.76e-3)" "unprognostic (2.84e-1)" "prognostic favourable (3.90e-5)" "unprognostic (8.36e-2)" "prognostic favourable (4.68e-5)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-1)" 9.5 12.3 21.6 10.6 18.8 10.2 10.2 34.2 22.4 10.0 12.1 16.9 14.6 11.2 15.0 14.6 8.8 14.6 13.0 15.2 25.8 17.9 13.8 12.8 10.6 13.2 15.0 16.5 17.2 16.9 17.1 18.0 12.9 15.2 16.0 11.6 13.3 19.5 17.1 28.2 16.6 11.9 12.1 13.4 12.3 10.7 49.9 13.4 8.7 11.6 5.5 11.0 7.8 9.5 2.8 5.1 3.4 3.8 3.8 10.8 4.9 6.7 10.7 9.8 16.4 12.6 10.2 17.7 7.8 9.6 12.4 8.5 11.2 9.4 2.1 9.4 17.9 15.1 11.9 8.4 6.5 11.0 17.1 3.8 25.3 7.8 14.9 9.9 8.6 7.1 7.6 8.2 2.8 10.7 6.8 11.4 12.4 17.9 9.3 22.6 5.6 13.5 10.8 9.2 16.0 10.9 2.0 11.0 9.8 13.2 15.3 7.7 22.5 10.0 11.6 9.8 2.1 17.7 6.5 7.1 6.2 3.5 5.8 18.6 8.0 0.0 3.8 3.4 7.4 3.6 10.8 2.8 7.2 7.4 5.1 2.7 6.7 5.5 0.5 3.8 3.3 3.1 7.6 4.9 21.6 18.8 34.2 22.4 25.8 17.9 15.0 16.5 15.2 13.4 POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320884 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" 6.7 10.8 10.4 6.8 11.4 3.8 7.7 12.5 13.3 6.8 6.3 18.0 9.8 4.6 6.9 17.1 5.7 8.7 6.9 7.7 9.3 7.7 8.1 8.3 6.2 3.0 11.7 6.2 7.6 10.6 14.7 16.1 11.4 9.7 7.3 5.8 8.2 10.1 12.3 17.0 4.3 4.6 7.8 8.4 5.2 5.6 30.9 14.4 2.5 11.5 4.9 3.8 5.7 5.0 1.4 1.9 0.8 1.9 0.0 1.7 0.4 10.6 13.6 13.3 15.0 9.5 7.6 10.6 9.4 7.7 14.0 12.0 6.7 9.6 3.1 7.6 8.8 11.9 6.2 9.4 9.8 4.7 8.5 1.9 6.8 5.5 11.6 2.1 6.4 7.7 10.0 13.1 12.9 8.1 5.0 7.5 9.2 21.0 3.6 10.3 3.7 11.6 3.6 12.9 2.9 14.6 7.8 11.2 11.0 6.1 10.4 7.8 10.7 4.5 6.7 10.6 16.8 12.2 8.2 4.9 9.6 1.4 5.4 3.3 9.3 0.0 0.4 0.0 1.7 1.9 0.4 1.4 0.0 0.3 0.9 0.2 0.1 0.0 0.8 0.0 0.8 1.9 0.0 0.4 10.4 11.4 12.5 13.3 9.3 7.7 11.7 6.2 9.7 14.4 PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036091, HPA036092" Approved Approved "Midbody ring" "Midbody ring" "HPA036091: , HPA036092: AB_10603132" "unprognostic (5.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.15e-5)" "unprognostic (1.38e-1)" "unprognostic (4.37e-3)" "prognostic unfavourable (1.14e-8)" "unprognostic (6.74e-3)" "unprognostic (2.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.88e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (8.34e-4)" "unprognostic (1.41e-1)" "unprognostic (3.01e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.09e-1)" 5.6 10.1 10.8 9.5 11.7 7.3 11.1 11.7 13.7 7.3 6.0 6.9 7.6 6.1 7.4 5.6 8.1 7.1 5.3 4.4 8.9 9.7 9.7 10.3 3.9 12.0 9.7 12.1 12.5 10.8 5.6 6.8 10.3 9.5 6.2 7.7 3.8 9.2 7.6 7.0 6.7 5.1 5.6 9.7 6.3 5.5 13.0 8.9 15.2 9.4 6.4 12.0 7.0 6.6 8.2 3.7 3.3 3.9 11.2 9.5 4.3 8.6 7.2 14.9 7.2 4.8 6.3 12.1 9.6 4.3 8.0 8.5 14.4 10.6 30.4 13.2 4.5 6.4 28.6 9.7 16.1 7.9 12.7 12.2 9.1 15.9 7.4 24.1 7.7 5.4 7.6 11.4 12.8 8.4 30.8 16.8 9.0 7.8 29.7 18.3 19.7 8.6 25.2 9.7 21.3 13.4 6.1 25.2 12.3 7.7 14.1 8.7 9.5 5.2 5.8 8.4 14.5 8.4 17.0 12.6 12.6 31.6 9.3 15.4 7.7 3.3 2.0 1.0 4.6 3.1 6.9 8.2 6.3 6.2 2.8 6.3 9.5 8.6 0.5 11.2 3.9 3.7 4.7 4.3 10.8 11.7 11.7 13.7 8.9 9.7 9.7 12.1 9.5 8.9 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666009-21700015 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm Nucleoplasm "HPA035344: AB_10672863, HPA055637: " "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 15.0 21.5 19.4 20.9 24.6 16.6 13.5 24.1 30.9 17.7 17.4 25.3 19.1 18.6 21.8 17.0 22.3 15.7 16.5 20.0 17.2 17.1 21.2 20.3 14.6 23.7 15.6 20.9 16.6 31.4 23.6 30.2 31.4 19.0 19.5 17.6 23.6 22.0 16.5 25.5 17.5 19.1 15.2 15.0 21.3 19.5 18.4 17.6 32.8 27.0 13.6 33.5 17.4 16.2 8.7 11.7 4.8 17.3 12.8 13.2 9.1 6.5 6.8 8.0 8.4 8.1 7.0 7.2 8.6 6.1 10.5 9.0 6.9 4.3 11.2 5.2 9.5 9.6 10.6 7.3 6.3 6.9 10.8 10.5 6.8 8.1 5.9 16.5 9.9 7.5 6.6 7.5 5.7 9.0 69.7 8.1 7.5 10.2 7.4 4.5 7.6 4.2 9.6 11.8 2.3 5.3 6.6 12.4 6.8 7.8 12.4 2.8 8.9 5.5 10.9 6.6 10.7 7.7 5.4 9.4 6.8 8.5 7.5 6.3 7.9 1.0 8.6 4.7 9.5 13.9 11.4 7.0 11.1 12.0 11.7 8.7 9.8 8.9 4.8 12.8 17.3 11.1 13.2 9.1 19.4 24.6 24.1 30.9 17.2 17.1 15.6 20.9 19.0 17.6 PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590253 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039380: AB_10673528" "unprognostic (8.72e-2)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.78e-1)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (2.59e-3)" "prognostic unfavourable (8.57e-4)" "unprognostic (6.67e-2)" "unprognostic (2.85e-3)" "prognostic favourable (7.14e-8)" "unprognostic (2.67e-2)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (7.95e-3)" 1.7 5.2 3.4 1.8 6.4 1.1 3.4 28.4 7.0 2.8 6.1 9.1 2.2 5.6 3.7 3.1 2.5 2.1 3.6 5.0 2.5 1.4 1.4 2.0 3.3 3.0 2.9 13.4 7.6 0.9 3.4 6.5 4.7 2.7 6.3 7.2 8.8 2.3 2.8 2.3 5.3 4.5 5.0 3.0 3.3 2.7 5.3 3.2 4.3 2.8 3.5 3.8 3.0 8.5 5.6 4.9 9.1 3.0 1.9 8.5 4.2 5.4 6.1 9.0 6.5 8.1 8.0 6.5 5.8 23.2 9.6 18.5 6.2 7.8 7.6 12.0 17.0 3.5 6.9 13.6 12.5 3.4 16.3 7.4 11.5 6.5 8.6 11.9 4.5 6.6 4.5 7.7 2.4 6.1 9.8 5.0 4.0 6.7 15.4 14.9 4.6 11.0 10.5 4.2 19.3 11.5 2.8 5.4 6.4 6.7 10.3 2.6 3.2 9.9 10.1 15.7 5.1 4.3 1.4 0.0 2.7 2.8 3.8 5.3 3.3 3.6 3.2 3.6 2.7 2.5 1.0 3.5 2.1 2.4 0.8 3.0 PPIP5K2 "CFAP160, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Enzymes, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037895, HPA038442" Approved Approved Vesicles Vesicles "HPA037895: , HPA038442: AB_10673173" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.93e-1)" "unprognostic (8.83e-2)" "unprognostic (1.60e-3)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.60e-2)" "unprognostic (8.59e-3)" "unprognostic (1.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.32e-2)" "unprognostic (1.29e-1)" "unprognostic (4.06e-1)" "prognostic unfavourable (1.12e-4)" "unprognostic (8.80e-2)" 21.6 20.5 12.6 18.2 18.4 37.9 22.3 30.7 24.2 26.1 23.8 9.7 16.0 14.3 22.6 20.3 17.0 18.5 17.7 16.4 13.2 17.6 21.9 22.6 14.8 20.6 19.5 18.7 26.8 25.5 22.3 40.3 21.6 37.2 18.4 22.1 10.5 17.4 21.7 5.7 16.4 20.2 16.0 19.8 27.7 18.6 13.5 16.2 38.5 20.0 12.9 20.3 16.9 18.2 12.1 15.7 24.3 18.2 10.0 11.2 6.7 9.6 9.5 18.4 21.3 15.0 19.4 16.6 20.1 14.0 12.7 17.4 7.9 16.4 22.8 19.7 20.1 5.9 15.9 12.0 20.7 18.0 8.4 28.9 17.8 12.6 11.0 24.9 26.3 12.9 9.0 17.8 16.4 14.0 29.9 21.0 18.7 8.1 21.5 17.5 20.0 22.2 20.5 16.4 31.2 13.5 11.2 10.3 13.5 13.8 14.5 13.6 11.4 16.9 14.0 18.1 8.1 20.1 15.0 13.3 30.2 30.9 10.6 39.6 16.9 23.0 13.4 24.3 8.7 13.8 10.7 12.1 8.4 9.0 15.7 11.3 11.1 11.2 13.0 10.0 18.2 9.3 7.3 6.7 12.6 18.4 30.7 24.2 13.2 17.6 19.5 18.7 37.2 16.2 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 93.3" "Cell line enhanced" "Detected in some" "A-431: 19.8;AN3-CA: 26.4;fHDF/TERT166: 14.7;HBEC3-KT: 16.6;HEK 293: 13.6;HEL: 15.9;RPTEC TERT1: 18.4;U-266/84: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles Vesicles "HPA043266: , HPA060174: " "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 36.0 18.2 18.5 8.3 21.6 4.4 12.9 9.8 31.7 11.0 27.0 17.3 7.9 33.2 16.0 93.3 26.8 33.7 23.9 16.8 16.6 17.6 18.2 22.6 12.9 13.2 15.5 14.5 26.2 33.1 5.9 8.8 21.1 14.6 13.6 4.6 14.0 20.4 8.8 39.0 37.0 28.6 9.4 13.4 16.0 27.2 18.1 11.4 16.9 20.6 10.9 29.6 15.8 12.4 2.6 2.7 4.4 3.5 0.8 3.2 1.8 19.8 0.0 0.0 26.4 11.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 16.6 0.0 0.0 13.6 15.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.4 8.6 0.0 0.0 0.0 9.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 17.6 7.7 0.0 0.0 0.0 2.9 2.6 4.4 1.7 3.5 2.0 2.1 1.9 3.1 1.3 2.6 2.7 2.1 2.9 0.8 2.9 2.7 3.2 1.8 18.5 21.6 9.8 31.7 16.6 17.6 15.5 14.5 14.6 11.4 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386498 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell line enhanced" "Detected in many" "A549: 28.1;NTERA-2: 18.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012066 Uncertain "HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favourable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 7.6 0.2 6.4 8.8 4.9 0.1 5.4 30.4 7.0 2.4 5.7 1.8 3.2 9.8 0.8 1.7 2.6 5.0 4.0 1.8 2.1 1.3 0.9 4.3 9.1 0.0 1.4 1.7 1.0 2.2 0.0 5.4 1.2 1.5 3.4 0.0 1.7 5.7 5.6 2.8 9.4 0.9 1.4 5.7 3.9 0.7 1.2 1.8 15.4 4.7 6.2 1.5 0.2 3.1 4.6 2.2 1.6 1.3 3.9 0.4 3.4 28.1 3.2 0.4 0.0 0.2 8.0 7.1 1.5 2.8 1.2 13.9 8.2 5.6 4.9 3.4 12.2 0.5 8.6 0.6 0.2 0.9 0.0 3.4 7.8 3.1 0.8 8.9 0.7 5.6 0.4 1.3 5.8 0.0 0.0 2.1 4.7 0.7 2.6 18.2 7.2 3.6 3.4 1.3 4.1 9.8 1.6 1.0 2.7 7.9 2.8 6.1 3.5 7.7 0.3 7.5 0.0 1.7 0.4 0.6 7.7 1.8 1.9 4.2 0.0 0.5 2.2 1.2 0.1 0.9 3.1 1.5 0.4 0.7 2.6 3.9 3.2 0.0 1.3 1.6 4.6 0.2 0.4 PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700198-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA005809: AB_1079673" "unprognostic (2.22e-1)" "unprognostic (3.28e-1)" "unprognostic (5.34e-2)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (2.72e-3)" "unprognostic (1.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-2)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (9.63e-3)" "unprognostic (3.81e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.85e-3)" 15.2 14.5 26.0 17.2 28.1 64.1 17.2 32.3 44.9 16.2 18.1 19.8 12.6 12.4 18.8 16.4 19.6 14.4 16.4 14.3 19.8 14.5 10.8 9.3 15.6 23.4 18.9 27.8 30.7 12.8 16.0 26.7 15.7 18.0 17.7 13.6 10.3 15.8 18.9 45.2 21.6 16.8 16.8 21.6 16.9 14.2 17.1 17.8 14.4 23.3 11.7 22.7 19.8 19.3 16.0 5.4 9.7 5.1 5.7 5.7 2.5 6.7 3.9 14.1 5.4 11.2 8.6 6.8 8.9 5.4 6.1 6.8 6.1 7.7 20.8 7.8 8.5 8.4 10.5 5.2 6.7 12.8 7.5 13.9 4.5 2.8 6.1 4.6 12.0 9.1 9.2 6.4 5.4 6.0 12.3 24.1 7.6 3.4 7.4 7.4 4.2 5.2 10.4 7.6 6.2 3.5 7.7 12.3 7.9 7.1 4.5 9.7 6.4 7.5 10.6 7.8 8.5 7.1 4.8 35.4 24.0 29.8 6.9 10.9 10.0 3.9 4.8 6.8 5.7 3.1 3.8 16.0 4.5 5.2 2.9 12.5 5.2 4.5 9.7 5.7 5.1 5.4 4.1 2.5 26.0 28.1 32.3 44.9 19.8 14.5 18.9 27.8 18.0 17.8 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089121-123194266 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 19.7;smooth muscle: 29.7;urinary bladder: 18.4;vagina: 18.7" "Cell line enhanced" "Detected in some" "BEWO: 6.8;HEK 293: 9.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "pons and medulla: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA030324 Uncertain Approved Nucleoplasm Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 1.3 0.3 0.3 0.6 0.3 0.0 1.4 0.4 0.5 1.6 6.7 0.4 0.3 0.4 1.8 0.6 1.2 0.6 19.7 0.9 0.4 0.3 0.6 0.3 10.6 0.0 0.5 0.4 3.8 0.5 0.3 0.5 8.1 3.6 14.1 1.9 0.0 0.3 0.8 0.2 0.4 1.0 29.7 0.8 0.1 1.1 0.5 0.0 0.0 1.4 0.2 0.6 18.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.6 0.9 6.8 0.1 0.0 0.0 0.1 0.1 0.3 0.1 0.2 0.5 0.0 1.4 0.0 0.0 0.3 9.6 2.0 0.9 0.0 2.0 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.1 0.4 0.1 1.5 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.5 0.4 0.3 0.5 0.4 3.6 0.0 PRDM7 ZNF910 ENSG00000126856 "PR/SET domain 7" Q9NQW5 16 90056566-90092072 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 4.8" "Group enriched" "Detected in some" 20 "REH: 8.9;SK-MEL-30: 6.5" "Cancer enriched" "Detected in single" 30 "melanoma: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA059944 Approved Uncertain "Nuclear speckles" "Nuclear speckles" "HPA059944: " "unprognostic (3.98e-1)" "unprognostic (8.89e-2)" "unprognostic (8.02e-3)" "unprognostic (8.26e-2)" "unprognostic (9.01e-2)" "unprognostic (5.61e-3)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (5.73e-1)" "unprognostic (5.52e-4)" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.03e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PRDM9 "KMT8B, MSBP3, PFM6, ZNF899" ENSG00000164256 "PR/SET domain 9" Q9NQV7 5 23443586-23528597 "Enzymes, Predicted intracellular proteins, Transcription factors" "Meiosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 4.1;epididymis: 3.3;testis: 8.3" "Cell line enriched" "Detected in some" 11 "U-266/70: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" HPA059555 Uncertain "HPA059555: " "unprognostic (1.23e-4)" "unprognostic (8.64e-2)" "unprognostic (2.18e-2)" "unprognostic (8.34e-2)" "unprognostic (4.11e-1)" 0.1 0.0 0.1 0.1 0.1 1.7 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 3.3 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.0 8.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.5 4.1 0.7 2.3 1.0 0.1 0.0 0.5 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.7 0.2 0.0 0.5 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.9 0.0 0.0 12.1 0.2 0.1 0.1 0.2 0.1 2.9 0.7 0.3 0.7 0.3 0.8 0.9 0.8 0.6 0.3 1.5 0.8 1.0 4.1 2.3 0.5 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB005050: AB_562037, HPA035409: , HPA064946: " "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.3 11.8 9.5 12.6 23.5 24.5 9.0 19.3 19.8 14.5 13.0 11.1 14.7 6.7 9.0 19.8 9.2 8.7 17.6 27.5 19.6 7.9 13.3 27.3 8.8 19.4 12.6 14.0 22.6 8.6 19.4 20.0 21.4 6.2 19.4 21.6 5.4 11.6 9.9 4.1 14.3 9.8 20.3 9.8 22.3 19.3 8.2 8.3 33.9 22.6 11.5 11.9 10.5 22.9 26.2 14.2 15.1 15.7 7.7 6.0 8.0 16.4 27.4 13.9 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;RPTEC TERT1: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" "Nuclear speckles" "Golgi apparatus" "HPA044540: " "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavourable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavourable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favourable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.5 4.3 3.8 4.7 0.0 0.6 0.6 0.0 7.8 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 0.8 0.0 0.0 1.0 0.1 0.0 0.0 5.5 5.4 0.0 0.0 0.0 14.0 1.2 2.0 5.4 5.7 0.1 0.0 3.2 0.0 0.0 1.5 2.3 2.7 6.3 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved Cytosol 1300000 Cytosol "CAB010361: AB_2268772, HPA071185: " "unprognostic (1.08e-1)" "prognostic favourable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavourable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favourable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 25.6 43.4 19.6 17.8 22.7 9.1 34.1 29.1 39.6 20.6 17.5 16.0 16.2 13.4 19.8 15.6 20.9 18.8 16.4 91.6 20.7 29.4 14.7 34.5 16.5 28.2 21.6 27.5 47.0 15.6 20.8 24.6 15.4 26.9 16.6 16.2 18.4 15.5 24.9 92.4 13.4 14.4 29.0 16.2 28.1 13.9 24.4 11.1 15.2 15.7 26.2 14.8 21.1 17.3 1.7 2.4 8.6 5.3 0.7 1.7 1.2 25.7 15.0 34.0 40.5 30.1 32.0 6.1 27.4 25.4 39.0 35.8 18.2 9.2 11.1 22.2 43.4 16.9 23.9 26.0 37.1 20.3 12.0 20.5 28.3 17.6 25.8 12.6 21.7 30.4 12.5 31.0 10.8 32.8 19.2 29.2 39.8 38.2 28.4 9.5 12.2 33.4 25.7 31.4 25.7 19.0 16.3 26.8 17.1 24.8 15.2 11.3 21.7 12.2 25.4 46.1 12.9 61.6 25.6 20.2 20.7 16.4 30.9 19.2 17.2 0.3 3.4 0.4 1.7 5.3 0.8 1.7 0.9 1.1 2.4 1.3 1.2 1.7 8.6 0.7 4.6 1.6 0.8 1.2 19.6 22.7 29.1 39.6 20.7 29.4 21.6 27.5 26.9 11.1 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved Cytosol 1500000 Cytosol "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: " "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavourable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favourable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 7.0 21.5 40.0 10.5 57.0 6.2 8.0 54.7 85.5 9.4 23.6 16.9 3.9 4.8 8.7 17.6 8.1 5.2 11.5 10.1 43.1 52.1 10.6 9.0 6.9 16.2 38.3 33.5 8.3 11.9 12.2 18.3 5.1 35.5 13.8 22.6 4.9 32.9 12.7 3.2 2.6 6.3 12.6 47.7 14.6 14.2 3.6 25.9 25.5 11.1 1.8 15.3 13.5 4.6 13.5 7.1 17.1 5.4 25.9 27.6 22.0 3.1 6.2 9.9 11.9 11.5 10.1 4.6 15.4 11.7 7.8 7.4 0.1 2.8 16.3 10.6 12.0 2.1 4.6 5.0 8.4 15.9 2.5 35.9 8.5 1.2 11.3 14.2 0.8 6.0 2.2 7.6 4.3 36.1 1.1 9.4 12.8 0.5 18.4 7.5 9.8 4.4 14.3 15.5 9.9 19.1 11.1 3.2 12.7 8.5 3.3 9.4 3.0 3.0 32.0 10.9 8.5 11.1 11.6 7.0 8.4 16.5 5.2 15.1 13.6 17.1 2.7 5.8 23.3 3.6 18.7 13.5 17.3 20.6 7.1 10.2 26.4 27.6 1.5 25.9 5.4 4.1 15.9 22.0 40.0 57.0 54.7 58.2 43.1 52.1 38.3 33.5 35.5 25.9 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012529-69014113 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 27.4" "Cell line enhanced" "Detected in single" "CACO-2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Approved Cytosol Cytosol "CAB004530: AB_628137, HPA071185: " "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.3 2.5 2.6 6.2 15.9 0.3 13.3 8.7 9.6 8.2 1.4 1.5 3.1 3.6 21.4 0.3 1.3 1.5 20.9 5.1 3.0 0.0 7.3 6.4 8.5 3.8 20.9 6.9 0.6 12.0 10.3 8.2 8.0 0.0 14.8 0.7 7.7 2.3 1.0 6.6 1.4 18.8 0.0 3.4 2.0 1.5 8.5 4.4 2.5 0.1 0.3 5.4 24.5 16.7 9.7 10.4 8.3 0.0 0.0 0.3 53.0 0.0 8.2 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell line enhanced" "Detected in some" "HEL: 40.8;HMC-1: 40.9;K-562: 58.1;THP-1: 18.4;U-937: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: , HPA054203: " "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 40.8 1.9 0.0 0.0 5.9 40.9 0.0 0.1 0.0 0.0 0.0 58.1 0.1 0.0 0.0 12.9 12.9 0.3 0.0 12.3 0.1 2.3 0.1 3.6 7.1 0.0 0.0 0.0 0.6 0.0 18.4 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 16.4 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 63.3;THP-1: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavourable (2.24e-4)" "prognostic favourable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.7 3.0 1.2 2.0 9.0 5.2 11.2 4.7 5.9 5.8 5.7 7.3 7.6 20.0 2.1 10.2 3.5 7.9 11.5 4.7 17.4 6.0 11.1 4.1 7.8 5.7 14.6 25.1 4.1 8.4 5.9 5.5 5.0 2.2 2.9 8.3 19.1 1.6 24.9 3.1 5.5 1.7 3.0 4.7 6.3 16.7 2.0 1.4 3.6 63.3 9.7 5.3 45.2 7.2 2.8 3.6 3.7 4.4 4.4 6.8 10.2 6.7 25.2 5.4 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Cell line enhanced" "Detected in many" "REH: 19.1;TIME: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA044496, HPA054252" Enhanced Supported Approved Vesicles Vesicles "CAB001948: , HPA044496: , HPA054252: " "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favourable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favourable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.3 2.0 2.8 2.8 4.3 5.1 2.3 3.8 6.8 3.2 3.4 0.5 5.3 8.1 3.6 3.9 1.3 1.8 2.0 4.5 4.8 3.4 0.0 1.4 1.1 4.9 0.6 2.9 4.5 2.2 4.7 3.4 11.6 1.1 1.9 3.6 2.7 2.6 0.3 1.0 1.0 19.1 13.5 8.6 2.9 3.7 2.0 4.3 1.7 5.7 12.3 4.6 1.9 19.2 6.2 6.5 4.5 3.7 0.0 0.0 6.8 5.1 4.5 6.2 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 PRKCG "MGC57564, PKCC, PKCG, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 49.9" "Cell line enhanced" "Detected in some" "A549: 5.8;HAP1: 2.7;SH-SY5Y: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013051, HPA047870, HPA054560" Enhanced "CAB013051: AB_2533015, HPA047870: , HPA054560: " "unprognostic (7.14e-2)" "unprognostic (5.42e-2)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-2)" "unprognostic (7.48e-3)" "unprognostic (2.68e-1)" "unprognostic (2.22e-7)" "unprognostic (2.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" 1.0 0.9 28.0 1.1 49.9 2.2 0.9 12.1 39.2 0.9 1.3 1.6 0.0 1.5 1.0 0.9 1.0 1.4 1.0 0.9 49.7 4.4 0.9 0.9 1.0 0.9 2.9 20.8 0.9 3.5 2.1 0.2 0.9 0.7 0.9 1.2 0.0 0.9 1.0 1.0 0.9 1.3 1.1 1.4 0.9 1.8 4.4 2.1 1.3 0.9 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 5.8 1.3 0.0 0.0 0.2 0.1 0.7 0.4 0.1 0.0 1.5 1.5 0.3 1.7 0.0 0.5 2.7 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.1 1.0 0.5 1.0 0.6 0.1 1.1 0.0 0.0 4.0 1.6 0.2 0.0 1.9 0.0 1.0 0.0 2.0 0.0 0.0 1.7 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 49.9 12.1 28.5 49.7 4.4 2.9 20.8 0.7 2.1 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 29.9;HUVEC TERT2: 39.2;MOLT-4: 26.0;RT4: 16.5;TIME: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "gdT-cell: 30.0;MAIT T-cell: 23.9;memory CD4 T-cell: 23.0;memory CD8 T-cell: 35.3;naive CD4 T-cell: 28.5;naive CD8 T-cell: 27.6;NK-cell: 27.3;T-reg: 18.6" "Group enriched" "Detected in many" 14 "NK-cells: 27.3;T-cells: 35.3" "Group enriched" "Detected in many" 6 "basal ganglia: 25.0;thalamus: 19.5" "Low region specificity" "Detected in many" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: " "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favourable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 17.5 5.4 5.0 21.6 22.0 11.2 14.7 2.8 6.1 13.6 10.3 6.2 6.9 5.1 19.1 7.0 20.1 8.6 12.7 10.1 6.8 4.4 8.1 5.5 24.1 27.6 5.9 2.5 7.1 5.9 8.8 15.5 22.7 7.2 9.8 5.0 9.1 24.7 10.8 9.1 15.9 16.0 10.5 5.7 25.9 6.0 4.3 6.4 54.6 15.1 10.6 34.6 13.2 14.4 0.4 2.2 1.5 0.7 27.3 35.3 17.9 6.2 2.2 0.3 1.7 1.0 0.2 29.9 0.1 0.5 0.3 0.3 0.6 3.7 0.1 4.5 0.0 4.4 0.2 4.8 0.5 0.7 2.8 0.0 0.7 0.2 0.4 0.0 0.9 0.8 5.0 0.2 3.4 39.2 0.0 0.1 2.2 11.5 26.0 0.2 0.5 3.0 2.2 1.1 0.0 0.0 16.5 1.1 1.9 0.7 5.8 3.6 5.7 0.5 25.7 0.7 5.2 0.7 0.3 0.5 0.1 0.2 1.1 0.3 1.2 0.1 0.7 0.5 30.0 0.4 23.9 0.4 23.0 35.3 2.2 0.3 28.5 27.6 1.5 27.3 0.2 0.7 18.6 17.9 5.0 22.0 2.8 6.1 6.8 4.4 5.9 2.5 7.2 6.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: " "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favourable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 35.9 9.1 9.2 9.8 8.2 11.4 14.9 9.2 13.7 12.3 13.3 13.3 17.6 11.0 30.5 13.0 16.9 17.3 18.1 21.1 8.0 10.7 10.2 11.6 7.4 13.0 9.2 4.6 10.2 12.7 10.4 16.5 9.5 11.2 9.1 12.3 12.4 13.3 3.6 19.3 10.2 9.6 14.2 18.2 19.3 11.0 14.6 11.9 20.0 26.3 9.0 28.9 6.3 10.1 12.8 9.9 11.9 15.2 15.7 15.1 15.7 9.2 7.2 5.0 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell line enhanced" "Detected in some" "HEL: 30.9;MOLT-4: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" 200000 "Centriolar satellite" "HPA065279: , HPA073098: " "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 1.8 3.3 0.0 0.0 2.1 30.9 0.0 0.2 0.4 1.5 0.3 0.1 2.0 0.1 0.1 0.3 6.7 0.0 0.0 0.0 23.2 4.3 3.2 0.0 4.5 0.7 0.0 6.5 1.6 0.2 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Cell line enhanced" "Detected in many" "BEWO: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favourable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.5 4.8 1.7 8.9 0.0 0.0 23.5 0.5 0.2 5.6 0.3 12.1 16.4 0.0 14.9 1.9 13.2 10.1 12.5 4.0 0.5 11.2 0.0 7.7 16.1 1.6 0.0 5.8 0.3 7.5 0.0 4.3 0.0 3.3 0.1 0.1 9.2 0.4 0.0 3.4 11.7 0.0 0.0 2.6 9.6 7.9 12.3 9.9 6.1 13.7 2.6 9.6 2.0 0.0 0.0 7.1 0.1 0.0 3.5 0.6 0.1 0.6 0.1 8.5 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;fHDF/TERT166: 19.0;HSkMC: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favourable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavourable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.0 17.8 16.7 0.1 12.1 9.3 12.4 6.7 0.0 0.5 0.0 1.2 19.0 0.1 5.9 1.4 6.8 0.0 4.1 0.0 0.1 0.4 9.0 0.0 0.1 17.7 0.6 0.8 1.4 2.5 1.2 0.4 11.6 1.3 0.0 0.0 2.5 6.2 0.0 7.0 3.2 13.2 5.6 3.6 7.1 2.1 0.0 4.7 0.0 0.1 6.3 11.7 4.8 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favourable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.6 13.4 5.3 6.5 4.4 3.6 6.8 4.5 7.1 9.4 10.3 7.4 8.5 10.1 7.9 6.0 12.9 4.7 12.0 2.9 8.6 7.0 10.6 4.2 3.9 5.8 7.7 15.7 4.3 5.8 5.4 4.6 16.5 6.8 14.6 3.9 9.1 14.8 25.0 4.5 6.8 9.7 2.5 16.3 5.8 12.9 3.4 10.8 8.4 7.0 1.8 5.6 3.1 7.8 4.0 8.0 3.4 3.6 14.3 56.9 5.0 4.2 6.4 4.2 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favourable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.6 5.4 14.3 11.8 10.9 18.4 10.5 8.2 15.3 9.3 9.5 8.6 4.5 18.6 6.9 12.3 5.0 9.7 10.1 12.6 24.0 14.2 12.2 8.3 5.8 4.5 8.7 7.5 8.6 5.2 14.7 9.7 16.5 10.2 22.9 10.8 2.1 3.8 6.8 15.1 5.2 12.8 22.6 15.9 6.2 14.3 10.8 28.0 7.9 4.5 48.2 4.9 8.0 15.9 26.7 13.9 10.6 9.2 26.2 48.5 21.7 9.3 3.7 16.0 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: " "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.4 27.8 27.1 25.7 16.9 17.9 11.5 13.8 13.6 19.5 19.2 18.1 10.7 31.0 12.0 16.9 18.5 35.8 18.9 30.6 6.8 22.2 60.9 25.0 22.2 7.3 23.1 12.7 12.9 6.2 30.7 32.2 20.0 40.5 13.1 21.4 15.2 32.6 19.1 29.8 8.4 16.0 21.3 10.9 9.8 28.0 13.6 17.3 42.6 13.9 13.4 19.9 16.0 23.2 25.5 21.7 20.1 27.7 11.5 14.6 44.6 14.4 26.3 20.6 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 PRKG1 "PGK, PKG, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase, cGMP-dependent, type I" Q13976 10 50990891-52298350 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 11.3;BJ hTERT+: 15.5;fHDF/TERT166: 12.9;U-138 MG: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "basophil: 8.0" "Lineage enriched" "Detected in single" 24 "granulocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol 33000 "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 8.0 10.9 5.2 6.6 7.3 0.8 6.9 2.8 5.4 19.2 14.4 2.1 6.8 2.9 22.8 10.7 6.0 9.9 12.6 14.8 7.0 4.9 4.4 2.1 19.5 2.6 3.1 4.8 8.9 2.6 13.7 8.4 11.0 4.6 9.5 6.2 6.2 6.4 9.4 24.9 2.8 5.3 28.2 2.7 2.7 5.9 5.0 3.1 0.2 9.2 12.7 1.2 13.4 15.8 0.1 0.1 8.0 0.1 0.3 0.0 0.1 0.0 0.1 1.4 11.3 5.4 5.2 0.0 4.9 15.5 1.6 2.3 0.1 0.7 0.2 0.0 12.9 0.1 0.0 0.0 1.4 0.0 4.2 0.8 0.3 0.0 4.7 0.0 0.0 6.6 0.0 4.1 0.1 0.0 0.0 0.1 4.3 0.1 0.0 0.0 3.2 1.9 0.0 3.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.0 9.5 1.7 4.8 2.9 1.2 0.5 0.0 8.4 0.0 2.0 8.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 5.2 7.3 2.8 5.4 7.0 4.9 3.1 4.8 4.6 3.1 PRKG2 "cGKII, PRKGR2" ENSG00000138669 "Protein kinase, cGMP-dependent, type II" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.3" "Cell line enhanced" "Detected in some" "ASC diff: 5.1;ASC TERT1: 3.9;HEL: 20.3;hTCEpi: 4.0;SCLC-21H: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 4.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.0;MAIT T-cell: 2.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 2.2" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 4.7 0.4 5.2 0.4 2.9 0.6 2.2 0.8 5.3 1.4 7.7 1.2 0.7 12.2 0.6 0.6 3.8 0.6 0.4 6.3 2.9 3.3 0.7 0.3 4.3 0.3 2.5 1.9 0.3 1.8 0.0 12.1 0.2 9.3 12.7 3.8 1.4 0.8 4.6 0.3 2.1 34.3 0.7 1.3 0.3 1.3 1.7 2.4 0.0 1.3 0.0 0.6 1.2 1.3 0.4 0.0 2.0 0.0 0.4 2.2 0.4 0.1 0.3 0.1 0.0 5.1 3.9 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.2 0.9 0.1 0.3 1.5 0.0 0.4 0.0 20.3 0.6 0.0 0.0 0.0 0.0 0.5 4.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.1 0.0 0.8 6.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 2.2 0.2 0.5 0.3 0.0 0.4 0.8 0.9 0.0 0.4 0.0 0.0 0.0 0.4 5.2 2.9 0.8 5.3 2.9 3.3 2.5 1.9 9.3 2.4 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347420-162727771 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.8" "Cell line enhanced" "Detected in some" "AN3-CA: 3.6;HEL: 9.0;Karpas-707: 5.7;RPMI-8226: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: " "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favourable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 6.8 7.1 7.9 2.3 12.2 1.5 4.2 7.2 13.4 5.3 4.3 6.3 4.6 2.8 7.8 4.4 6.1 3.4 4.3 17.7 9.2 6.2 17.4 3.6 2.6 3.0 5.8 5.2 6.4 3.0 5.6 8.6 2.0 5.5 4.0 2.4 8.3 3.5 4.8 41.8 4.0 3.3 6.6 5.9 2.7 3.5 10.3 6.8 0.6 3.8 4.7 2.7 4.9 2.1 4.6 1.2 4.2 0.8 1.8 4.6 1.3 0.0 0.3 1.2 3.6 0.9 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 9.0 0.2 0.0 0.8 0.2 0.1 3.1 0.1 0.0 0.5 0.0 0.4 5.7 0.9 0.5 0.1 0.1 0.2 0.8 0.0 0.0 5.7 0.6 0.1 0.9 2.5 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.3 0.1 0.3 0.8 0.1 0.0 0.1 0.1 2.2 2.8 0.8 4.2 2.1 0.5 3.5 1.5 2.0 2.2 1.2 4.6 4.4 4.6 1.5 1.8 0.4 0.3 0.2 1.3 7.9 12.2 7.2 11.7 9.2 6.2 5.8 5.2 5.5 6.8 PRKX PKX1 ENSG00000183943 "Protein kinase, X-linked" P51817 X 3604370-3713608 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 4.3 1.3 12.3 7.5 15.8 5.4 11.2 4.4 12.3 6.9 5.2 5.4 11.5 4.1 7.3 8.4 13.6 16.5 3.9 4.0 14.0 7.4 14.2 2.0 8.4 9.5 27.9 5.6 4.8 4.1 3.2 2.3 6.6 22.7 3.7 5.2 3.1 6.5 5.3 1.6 9.9 6.0 3.0 17.6 10.0 3.1 6.1 22.7 6.1 28.8 3.2 8.0 3.7 11.2 2.5 2.8 12.2 4.1 3.3 3.8 1.7 4.5 4.2 11.6 8.6 2.2 3.0 10.6 2.7 1.0 1.3 1.8 6.2 3.1 0.4 2.7 2.1 3.1 10.8 8.1 2.3 5.0 7.5 5.0 3.2 0.1 2.3 6.4 38.9 2.0 8.7 1.4 5.4 13.1 5.8 6.5 4.4 3.9 7.3 5.8 7.7 4.8 13.7 11.1 8.5 10.7 3.8 7.8 5.0 2.8 1.8 2.7 1.4 5.1 7.1 1.2 2.0 1.9 1.8 0.1 0.3 5.8 0.7 5.8 3.0 12.2 3.1 1.8 3.5 3.3 3.8 2.5 3.7 3.3 2.3 2.4 3.1 3.3 0.8 3.3 4.1 2.8 2.5 1.7 12.3 15.8 4.4 12.3 14.0 7.4 27.9 5.6 22.7 22.7 PRMT1 "ANM1, HCP1, HRMT1L2" ENSG00000126457 "Protein arginine methyltransferase 1" Q99873 19 49675786-49689029 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022550, HPA069769, HPA072136" Supported Supported Nucleoplasm Nucleoplasm "CAB022550: , HPA069769: , HPA072136: " "unprognostic (1.88e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-2)" "unprognostic (3.84e-1)" "unprognostic (4.13e-2)" "unprognostic (3.33e-2)" "prognostic unfavourable (8.04e-5)" "unprognostic (3.43e-2)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.05e-1)" "unprognostic (7.19e-3)" "unprognostic (2.21e-1)" "unprognostic (3.66e-2)" "unprognostic (4.73e-2)" "unprognostic (1.10e-2)" 21.3 31.5 27.4 28.1 29.7 21.8 22.0 29.4 35.9 31.8 25.5 26.9 27.8 21.4 36.0 22.5 28.9 45.4 24.5 56.4 25.2 28.6 23.4 20.8 22.0 34.9 32.0 23.8 43.4 35.0 20.0 31.7 27.9 25.6 33.3 18.4 34.1 20.9 31.5 83.8 21.9 19.8 38.3 20.9 33.3 20.3 24.9 28.0 25.0 32.9 31.3 32.0 29.8 23.8 51.9 41.2 9.2 23.6 38.7 35.5 31.8 37.9 86.9 60.3 72.7 16.4 18.6 31.8 24.4 42.7 70.6 60.8 64.8 30.3 62.5 18.2 28.6 28.1 50.8 51.6 30.9 48.5 87.2 45.6 23.9 70.3 40.1 54.8 32.8 26.0 25.7 39.5 56.9 41.7 47.9 44.4 27.4 57.4 70.7 67.8 63.6 56.6 50.3 48.7 57.0 39.7 80.2 67.3 52.4 28.1 29.2 14.9 22.1 32.3 25.9 41.6 40.4 19.0 58.1 42.8 64.4 61.7 25.5 39.7 43.5 5.8 20.2 9.2 28.6 23.6 35.5 51.9 26.6 30.5 34.2 41.9 29.9 29.1 3.9 38.7 17.1 41.2 24.2 31.8 27.4 29.7 29.4 35.9 25.2 28.6 32.0 23.8 25.6 28.0 PRMT2 "HRMT1L1, MGC111373" ENSG00000160310 "Protein arginine methyltransferase 2" P55345 21 46635167-46665124 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018976, HPA029591" Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA018976: AB_1855719, HPA029591: AB_10601250" "unprognostic (1.82e-1)" "unprognostic (2.96e-1)" "unprognostic (8.61e-3)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (1.58e-2)" "unprognostic (1.29e-3)" "unprognostic (1.34e-1)" "unprognostic (2.23e-1)" "unprognostic (6.78e-2)" "unprognostic (4.34e-3)" "unprognostic (1.72e-1)" "unprognostic (4.62e-3)" "unprognostic (8.76e-3)" "unprognostic (2.86e-2)" "unprognostic (1.91e-3)" "unprognostic (2.23e-1)" 19.9 14.7 37.1 21.8 43.6 18.7 28.4 21.4 37.2 25.5 25.2 35.4 12.0 14.7 24.5 15.9 30.7 27.1 23.4 29.4 37.4 53.1 19.9 8.5 21.7 28.7 44.8 32.2 48.5 15.1 19.9 20.1 26.2 44.9 22.0 17.1 20.6 21.0 28.0 9.5 28.1 20.0 28.5 69.6 25.6 17.4 10.1 40.3 13.8 20.1 7.4 28.3 23.1 26.0 18.9 27.6 64.2 26.1 50.8 60.2 41.6 22.7 19.5 39.5 14.7 28.8 28.2 9.7 21.5 24.2 24.4 22.3 27.4 18.6 13.4 27.3 38.3 6.7 18.4 27.1 14.2 33.4 17.7 34.7 16.5 20.4 13.9 10.3 16.5 17.4 27.0 29.6 21.2 35.2 22.0 25.2 37.3 25.4 14.8 19.4 21.6 23.0 19.1 10.0 8.8 19.0 19.5 28.6 17.8 22.7 10.4 41.0 14.0 10.7 31.8 23.9 16.4 12.6 14.1 6.7 6.1 8.5 21.9 28.1 34.4 44.2 19.6 64.2 60.2 26.0 43.6 18.9 40.5 51.0 27.6 16.7 49.9 56.9 26.3 50.8 26.1 23.8 29.0 41.6 37.1 43.6 21.4 37.2 37.4 53.1 44.8 32.2 44.9 40.3 PRMT5 "HRMT1L5, SKB1, SKB1Hs" ENSG00000100462 "Protein arginine methyltransferase 5" O14744 14 22920511-22929585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005525, CAB012459, HPA064708" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB012459: , HPA005525: AB_1079679, HPA064708: " "unprognostic (8.34e-2)" "unprognostic (5.14e-3)" "unprognostic (1.19e-2)" "unprognostic (2.19e-1)" "unprognostic (4.56e-3)" "prognostic unfavourable (1.82e-4)" "prognostic unfavourable (4.77e-5)" "unprognostic (3.64e-2)" "unprognostic (6.80e-2)" "unprognostic (1.48e-1)" "prognostic unfavourable (2.61e-4)" "unprognostic (4.69e-2)" "unprognostic (1.99e-3)" "unprognostic (1.21e-1)" "unprognostic (7.04e-2)" "unprognostic (6.28e-2)" "prognostic unfavourable (1.04e-4)" 17.0 21.6 18.3 17.8 22.8 12.0 21.2 18.4 24.9 20.3 25.0 18.1 24.9 16.1 24.9 19.6 33.1 28.0 16.6 22.3 15.3 13.2 25.7 22.2 15.8 15.6 17.2 15.2 30.2 30.9 30.8 17.4 24.3 15.9 21.1 22.6 16.9 19.0 21.7 42.0 21.7 14.5 22.2 13.4 17.9 19.5 22.1 17.3 22.7 30.9 19.6 22.1 20.8 22.0 17.6 23.8 4.3 17.6 9.8 15.6 15.5 40.0 38.7 28.0 27.7 13.3 15.2 30.5 27.6 20.5 42.9 36.4 35.4 37.3 39.1 22.6 20.3 32.0 55.4 46.4 49.6 25.1 26.8 24.3 26.1 54.4 25.6 51.0 21.2 15.0 24.8 33.2 60.6 20.3 34.4 21.4 22.1 36.2 36.4 22.8 25.0 49.0 43.1 34.0 28.4 20.8 27.5 30.2 19.8 30.1 32.4 14.1 21.8 19.3 19.0 18.2 26.0 25.9 35.1 29.4 62.6 52.0 11.5 24.8 28.4 1.7 16.8 0.2 8.2 17.6 13.4 17.6 11.3 13.5 23.8 15.5 15.6 12.5 4.3 9.8 13.2 14.1 9.4 15.5 18.3 22.8 18.4 24.9 15.3 13.2 17.2 15.2 15.9 17.3 PRMT6 "FLJ10559, HRMT1L6" ENSG00000198890 "Protein arginine methyltransferase 6" Q96LA8 1 107056679-107059294 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "MCF7: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059424 Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA059424: " "unprognostic (5.17e-3)" "unprognostic (1.48e-1)" "unprognostic (1.47e-2)" "prognostic unfavourable (3.05e-4)" "unprognostic (2.68e-1)" "unprognostic (2.55e-1)" "unprognostic (1.36e-3)" "unprognostic (2.13e-2)" "unprognostic (9.72e-2)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (3.15e-2)" "unprognostic (1.03e-1)" "unprognostic (8.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.73e-3)" 6.6 16.1 14.4 10.5 13.4 4.6 10.8 12.6 13.9 8.9 10.3 11.5 10.4 8.1 9.7 11.3 10.9 12.2 9.8 5.0 11.8 16.2 16.7 16.3 5.9 11.5 12.2 14.1 12.3 16.8 15.0 13.8 9.6 13.2 11.8 9.7 12.6 8.3 11.4 2.1 7.6 9.3 8.0 13.6 11.5 9.5 9.4 10.6 18.2 9.5 3.4 11.1 10.1 7.3 9.7 14.7 1.8 10.1 14.6 10.9 7.6 3.5 0.0 7.1 3.1 4.7 5.2 1.9 4.8 3.6 4.7 4.8 4.6 2.5 8.8 6.7 4.4 5.1 6.5 7.1 3.7 0.0 6.9 5.3 10.0 6.6 4.7 10.9 3.3 4.9 3.9 4.2 4.3 4.0 7.1 1.3 4.2 81.7 6.4 3.8 3.0 6.7 8.1 15.5 3.3 11.3 7.3 13.3 16.2 6.5 9.5 3.1 6.6 8.2 4.6 3.5 7.1 7.2 7.1 1.5 1.0 1.5 5.1 5.1 2.8 1.8 8.9 1.6 7.5 10.1 8.4 6.9 7.6 6.8 11.9 9.7 10.9 10.9 0.5 14.6 9.2 14.7 7.8 7.6 14.4 13.4 12.6 13.9 11.8 16.2 12.2 14.1 13.2 10.6 PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310974-68358563 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "HPA044241: " "unprognostic (9.33e-2)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "prognostic favourable (2.31e-5)" "unprognostic (2.92e-2)" "unprognostic (1.95e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "unprognostic (4.74e-3)" "unprognostic (3.09e-2)" "unprognostic (7.72e-2)" "unprognostic (1.75e-1)" "unprognostic (9.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" 14.8 14.4 15.6 12.7 22.0 11.1 12.9 29.4 20.5 11.4 11.7 20.2 13.9 7.0 18.9 11.9 12.7 18.1 9.3 23.1 14.4 13.1 9.5 12.2 9.7 17.0 11.2 18.7 21.9 14.8 12.0 14.0 11.4 13.3 12.8 7.6 20.8 17.3 16.2 34.0 16.9 9.9 18.5 11.6 12.4 9.9 17.0 13.1 24.4 11.1 12.0 14.9 13.3 10.4 10.8 26.2 9.9 8.5 18.6 18.1 11.5 10.1 16.5 7.8 19.7 7.5 7.1 26.3 10.2 5.5 12.9 10.7 41.6 10.2 21.6 17.1 8.6 13.2 11.1 10.3 7.1 7.7 16.7 6.4 18.5 18.8 5.5 11.8 10.0 7.8 4.4 10.6 10.0 7.7 15.1 1.2 7.0 17.0 14.5 18.2 12.9 11.2 19.5 11.5 14.6 6.0 9.3 10.8 8.4 34.0 8.6 6.9 14.3 11.7 9.2 9.2 8.1 10.9 9.0 6.6 12.3 22.1 11.6 12.6 9.4 9.9 7.0 5.9 15.8 8.5 18.1 10.1 10.6 13.9 10.2 10.8 16.1 14.1 0.8 18.6 7.7 26.2 11.7 11.5 15.6 22.0 29.4 20.5 14.4 13.1 11.2 18.7 13.3 13.1 PRMT9 "FLJ46629, PRMT10" ENSG00000164169 "Protein arginine methyltransferase 9" Q6P2P2 4 147637785-147684230 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036844, HPA042537" Uncertain Approved Nucleoplasm,Microtubules,Cytosol Microtubules "Nucleoplasm, Cytosol" "HPA036844: AB_10672341, HPA042537: " "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" "unprognostic (4.65e-3)" "unprognostic (2.35e-1)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (4.14e-2)" "unprognostic (7.29e-2)" "unprognostic (2.11e-2)" "unprognostic (2.33e-1)" "prognostic favourable (3.58e-7)" "unprognostic (1.72e-1)" "unprognostic (4.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.30e-2)" 6.0 17.2 6.0 5.2 8.6 12.4 6.9 8.0 8.9 5.6 4.5 4.2 7.9 2.5 8.6 7.6 5.0 7.5 8.4 6.5 5.6 5.0 7.5 5.8 7.6 5.3 5.8 5.3 22.6 7.2 16.3 10.0 5.0 7.1 6.0 4.5 9.8 5.8 11.3 6.7 5.6 4.3 6.1 4.6 4.5 5.9 11.2 3.9 11.6 15.8 2.8 5.4 5.5 5.2 9.6 6.0 10.8 6.1 5.1 10.4 2.7 3.5 2.3 5.6 4.3 4.4 7.4 4.9 3.9 6.2 5.9 6.3 1.8 3.9 12.1 1.8 3.3 2.4 6.5 3.3 8.2 4.4 3.8 6.7 4.4 3.0 3.3 9.7 3.7 5.1 3.5 3.6 3.2 4.9 6.5 7.0 5.0 2.0 8.2 3.8 2.9 4.2 5.6 4.8 4.4 4.8 2.8 3.5 5.3 6.2 4.9 3.2 2.1 2.1 4.2 3.8 3.1 4.2 4.2 8.0 6.4 7.9 4.3 6.0 2.8 7.4 6.0 10.8 6.7 6.1 6.5 9.5 8.1 8.2 4.0 9.6 10.4 9.0 4.2 5.1 4.4 6.0 6.8 2.7 6.0 8.6 8.0 8.9 5.6 5.0 5.8 5.3 7.1 3.9 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890730-60906588 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 20.5 32.2 33.6 27.0 37.9 32.0 28.9 49.6 61.8 30.4 30.6 21.3 24.5 24.2 27.1 21.4 36.7 34.9 20.1 18.0 32.8 46.3 21.5 39.4 18.0 33.1 35.0 50.0 41.3 31.3 45.7 37.6 24.9 46.2 37.7 31.5 21.5 28.8 30.9 31.9 39.0 24.6 28.8 23.7 28.3 23.7 15.2 24.4 46.3 25.3 24.4 41.7 24.8 24.8 3.1 5.3 4.4 11.8 2.4 3.3 1.2 43.8 34.3 38.6 27.5 22.6 19.9 35.0 23.9 32.5 48.1 36.2 37.7 33.2 63.6 32.2 22.9 40.3 54.2 43.1 37.4 43.3 34.6 52.9 27.2 40.4 32.8 69.9 37.8 21.1 32.8 36.9 41.6 37.3 52.5 36.8 23.5 61.8 70.5 52.6 68.2 46.3 62.7 39.5 49.8 24.3 28.8 32.9 39.6 29.6 49.3 39.8 51.5 38.7 23.3 21.3 34.3 37.1 38.6 32.9 46.0 64.0 26.5 48.0 32.0 4.4 11.8 2.6 3.2 5.4 2.6 1.3 2.6 2.3 4.8 3.1 3.3 3.0 0.7 2.4 2.9 5.3 2.2 1.2 33.6 37.9 49.6 61.8 32.8 46.3 35.0 50.0 46.2 24.4 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavourable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favourable (6.82e-5)" 23.2 21.6 19.6 24.0 20.5 8.5 21.4 35.6 26.8 18.3 19.3 6.0 14.7 12.0 22.2 14.2 23.6 14.7 13.6 16.3 16.5 11.7 15.0 14.5 13.0 15.4 14.5 14.1 19.1 14.4 20.9 30.9 17.1 21.0 14.9 15.7 5.3 22.7 20.4 45.7 16.3 16.4 14.9 23.7 19.0 13.6 11.6 20.2 21.8 21.1 11.3 17.4 21.4 22.2 9.7 13.6 7.5 11.9 11.8 9.1 3.9 14.4 12.6 19.8 13.6 11.3 10.5 9.6 14.1 15.5 15.4 15.5 12.0 7.3 23.8 17.8 15.8 13.0 25.0 12.2 22.1 11.1 18.3 26.7 14.4 10.7 8.7 29.4 14.6 9.6 8.1 10.9 6.8 15.3 36.5 8.8 15.0 8.5 21.6 9.9 11.9 11.7 24.5 19.2 23.0 9.8 16.4 15.4 10.1 16.3 10.2 12.4 15.9 14.8 16.3 15.1 8.7 9.9 13.6 10.0 15.6 27.7 8.3 13.5 18.4 7.5 11.9 3.6 7.6 9.9 9.1 9.7 8.6 9.0 10.2 9.3 8.0 8.0 6.1 11.8 8.7 13.6 6.3 3.9 19.6 20.5 35.6 26.8 16.5 11.7 14.5 14.1 21.0 20.2 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628424-107651026 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA043760 Uncertain 140000 "HPA043760: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 16.8 19.0 18.8 18.7 22.4 33.5 13.0 27.0 30.3 13.5 12.1 20.5 7.0 7.3 16.6 10.4 11.8 17.6 9.6 19.9 19.0 26.5 18.5 45.1 14.9 25.4 21.8 17.5 21.4 17.8 20.0 18.2 10.0 26.9 14.9 12.4 15.0 11.2 12.4 31.2 8.4 10.8 20.0 19.3 19.4 10.8 11.3 13.6 32.3 29.9 11.3 28.6 16.9 10.7 18.2 8.5 12.6 8.7 14.4 22.1 11.6 20.2 30.2 13.4 15.5 7.5 5.9 4.6 59.7 12.4 34.0 28.8 13.0 8.7 33.5 25.9 21.7 8.3 39.9 12.3 34.9 16.6 24.8 17.8 30.0 16.9 6.9 33.0 13.3 6.7 7.2 20.6 13.5 11.6 28.4 40.6 15.7 10.9 22.3 17.8 48.5 26.1 26.0 21.5 26.9 13.3 11.7 22.1 11.9 29.6 17.9 12.0 8.2 13.8 6.9 22.1 10.4 24.2 23.6 13.9 22.7 36.5 11.4 35.8 13.8 4.8 5.2 12.6 15.7 8.2 17.6 17.0 19.7 19.3 6.2 18.2 22.1 18.7 3.1 14.4 8.7 8.5 20.1 11.6 18.8 22.4 27.0 30.3 19.0 26.5 21.8 17.5 26.9 13.6 PRPS1L1 "PRPS3, PRPSL" ENSG00000229937 "Phosphoribosyl pyrophosphate synthetase 1-like 1" P21108 7 18026774-18027863 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 38.4" "Cell line enhanced" "Detected in some" "BEWO: 1.2;K-562: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "unprognostic (2.39e-2)" "unprognostic (3.18e-2)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.7 0.3 0.6 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.4 0.3 0.6 0.8 0.9 0.5 0.1 0.4 1.1 0.7 0.1 0.6 0.1 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 138.1;testis: 109.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067599, CAB070417" Enhanced Uncertain Vesicles Vesicles "CAB070417: AB_11152035, HPA067599: " "unprognostic (7.50e-2)" "prognostic favourable (1.90e-4)" "unprognostic (2.09e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (4.75e-2)" "unprognostic (6.98e-2)" "unprognostic (2.64e-3)" "unprognostic (4.44e-3)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" 5.4 20.8 4.0 10.2 8.7 6.1 6.1 3.7 11.5 18.7 13.3 5.7 44.4 4.1 17.0 21.7 9.6 9.6 13.2 3.3 4.0 3.5 10.8 9.0 5.4 10.7 2.7 7.7 75.3 19.9 20.1 2.4 3.2 2.9 14.9 10.2 4.4 11.1 138.1 1.5 10.3 6.3 12.2 3.9 7.6 14.3 109.7 3.1 26.2 7.8 5.5 10.9 15.1 10.2 21.9 17.7 10.5 12.5 15.0 22.7 16.7 31.0 20.6 7.2 13.0 8.9 10.5 4.0 15.5 8.5 17.2 16.7 14.6 25.0 9.1 7.0 7.4 23.6 13.8 16.9 20.3 24.5 29.8 11.2 17.0 13.5 8.2 22.1 11.5 10.1 11.4 12.7 17.0 7.0 8.3 12.7 14.5 21.4 33.7 10.2 15.3 27.8 18.0 30.8 23.3 10.3 25.8 13.9 9.4 18.7 0.7 11.7 18.6 10.0 6.5 13.5 9.8 49.5 16.5 30.0 11.0 21.7 14.2 11.2 21.2 10.5 12.5 5.6 11.7 12.4 13.6 18.0 17.0 11.1 17.7 21.9 22.7 15.3 5.5 15.0 7.7 12.6 14.0 16.7 4.0 8.7 3.7 11.5 4.0 3.5 2.7 7.7 2.9 3.1 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297143-78330093 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 56.0;liver: 112.2" "Cell line enhanced" "Detected in many" "hTCEpi: 148.4;SK-MEL-30: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 13.3" "Lineage enriched" "Detected in many" 4 "T-cells: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol 1700000 Cytosol "CAB014882: , CAB040567: , HPA042924: " "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavourable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 3.1 25.0 44.6 3.8 33.4 1.7 3.0 8.5 50.5 2.4 3.3 44.8 0.9 3.2 2.7 28.4 9.3 16.0 1.6 1.4 33.9 22.3 56.0 112.2 1.6 4.5 42.2 24.6 3.7 54.6 4.8 2.1 2.2 21.9 5.3 3.3 8.1 26.2 2.8 1.1 24.7 2.8 2.3 29.8 2.4 7.0 5.1 35.0 2.2 13.7 4.9 5.9 4.2 2.6 3.0 0.2 0.2 0.1 0.0 13.3 3.1 26.8 18.1 15.2 27.0 4.5 5.3 36.0 22.8 16.3 11.6 21.8 4.6 5.2 17.4 10.1 51.3 26.7 26.0 25.2 17.4 17.0 9.2 5.9 8.3 35.5 41.8 33.2 10.7 16.9 148.4 15.4 41.3 10.6 6.4 45.0 9.6 10.0 11.3 5.3 34.9 19.8 5.6 9.9 20.5 15.8 6.2 6.9 16.1 6.3 11.0 90.8 5.2 41.9 2.4 2.9 9.5 10.8 18.5 30.6 28.2 0.1 34.3 26.3 13.9 0.0 0.0 0.0 4.9 0.0 5.7 3.0 4.8 6.5 0.2 1.0 7.9 7.3 0.2 0.0 0.1 0.0 13.3 3.1 44.6 33.4 8.5 24.9 33.9 22.3 42.2 24.6 21.9 35.0 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053927 Approved Approved Nucleoplasm Nucleoplasm "HPA053927: AB_2682312" "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favourable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.3 13.1 14.9 16.5 23.3 11.8 9.7 8.8 13.5 9.4 8.4 9.9 10.6 6.9 13.5 14.9 11.2 8.6 9.1 3.2 2.7 9.6 7.9 9.7 12.5 16.0 7.5 4.8 21.7 15.8 11.1 11.8 13.7 12.0 3.0 9.7 16.4 10.2 4.8 14.3 8.2 15.7 5.7 14.3 11.1 9.2 13.0 15.5 27.4 7.5 9.0 13.8 13.7 12.0 10.6 3.8 8.8 4.4 9.1 4.8 14.9 12.8 5.1 11.6 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell line enriched" "Detected in single" 18 "HEL: 13.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: , HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 2.8 5.6 7.0 2.5 8.8 12.5 8.8 4.3 10.4 5.8 4.3 10.5 4.7 4.6 5.4 11.4 3.7 5.6 3.5 4.7 7.5 7.3 5.5 10.6 2.8 4.0 8.8 8.7 3.8 5.4 4.2 7.2 3.7 9.3 5.6 4.3 3.8 4.3 3.6 6.8 3.8 3.8 5.4 8.7 2.9 3.0 11.1 8.6 2.9 6.8 1.4 3.6 4.8 3.2 6.5 7.4 6.3 5.5 6.6 10.0 6.0 5.4 3.8 2.0 1.0 2.5 4.7 2.6 2.0 5.2 4.6 5.5 5.6 4.8 5.5 5.0 3.7 2.9 1.0 4.6 5.3 2.9 10.2 3.7 0.9 4.4 6.0 7.6 4.6 5.2 8.0 4.1 7.9 3.2 5.1 8.5 6.7 8.1 2.6 4.7 4.7 5.5 5.5 3.6 5.0 6.9 3.3 2.2 2.4 4.6 5.2 7.6 2.4 0.6 3.8 3.6 3.4 1.4 5.2 3.1 1.7 7.5 3.3 5.2 1.4 0.0 5.5 6.3 8.9 3.3 10.0 6.5 6.9 8.4 7.4 5.8 9.2 9.4 0.6 6.6 3.9 7.0 4.2 6.0 7.0 8.8 4.3 10.4 7.5 7.3 8.8 8.7 9.3 8.6 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261715-96336995 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavourable (1.08e-5)" "prognostic unfavourable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 8.2 7.9 8.0 8.1 14.7 10.2 10.4 10.2 15.0 9.7 8.3 5.1 22.5 10.6 8.4 7.8 9.6 7.0 7.9 20.1 8.6 9.9 9.5 12.8 7.8 21.8 7.1 8.0 9.6 12.1 23.2 4.9 10.8 9.6 5.7 7.4 5.2 8.8 29.8 10.1 10.4 8.3 9.0 6.0 11.8 8.1 5.1 3.6 20.7 11.0 7.7 11.8 9.3 6.8 3.6 6.1 9.4 3.7 5.0 4.6 7.8 10.4 8.1 1.4 3.9 2.9 6.1 2.4 7.6 10.5 7.3 5.1 3.0 3.0 17.2 7.0 7.1 4.3 9.9 7.6 11.4 8.8 7.1 16.9 15.6 1.6 3.0 12.4 5.9 5.1 7.3 10.2 7.2 4.7 8.4 8.9 6.6 3.0 9.6 1.9 2.2 7.6 7.7 7.3 13.0 4.1 8.9 6.1 2.5 2.8 2.5 1.1 5.9 4.2 8.3 6.6 4.1 4.5 8.7 1.8 9.2 8.4 4.1 13.1 5.3 9.4 3.7 2.1 2.8 2.5 4.0 2.6 4.6 3.4 6.1 3.6 4.0 2.9 1.3 5.0 2.4 1.8 2.6 7.8 8.0 14.7 10.2 15.0 8.6 9.9 7.1 8.0 9.6 3.6 PTDSS2 PSS2 ENSG00000174915 "Phosphatidylserine synthase 2" Q9BVG9 11 448268-491399 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038928, HPA038929" Approved "HPA038928: AB_10672832, HPA038929: " "unprognostic (3.41e-1)" "unprognostic (2.52e-1)" "unprognostic (2.07e-1)" "unprognostic (5.75e-3)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "prognostic unfavourable (5.12e-9)" "unprognostic (6.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-2)" "unprognostic (1.41e-3)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.39e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" 14.6 15.5 14.8 8.0 15.3 6.2 14.9 20.0 19.9 12.2 10.1 19.3 13.6 5.2 11.9 12.0 9.3 14.2 10.8 15.9 15.4 13.1 19.8 11.2 10.4 7.8 15.6 12.0 17.6 17.6 35.2 10.4 14.9 13.7 11.9 7.1 13.5 12.2 14.6 18.6 8.3 7.2 13.1 17.3 9.1 11.7 32.0 15.1 10.6 16.5 8.3 6.6 12.7 10.2 0.1 1.2 0.0 1.3 0.8 1.8 0.0 8.3 7.7 6.9 10.3 6.2 10.1 9.0 7.3 8.6 9.1 8.3 2.0 5.7 4.5 6.2 8.9 13.7 8.4 11.3 4.5 7.5 35.4 5.6 5.5 4.3 11.9 7.5 4.9 11.5 8.6 3.2 5.7 7.1 16.3 1.4 7.0 0.8 7.2 6.9 10.2 18.8 7.7 7.9 2.1 6.5 1.4 10.8 5.9 10.1 6.5 7.8 2.3 4.2 9.0 4.4 2.9 2.2 4.6 5.8 2.4 1.9 7.6 3.5 3.1 0.0 0.5 0.0 1.1 1.3 0.3 0.0 0.1 0.2 0.5 0.1 0.7 1.8 0.0 0.8 0.2 1.2 0.3 0.0 14.8 15.3 20.0 19.0 15.4 13.1 15.6 12.0 13.7 15.1 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" 32000 "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavourable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 22.6 20.4 36.0 14.4 42.3 3.1 19.3 20.5 40.8 24.9 17.9 55.7 23.5 14.5 20.2 29.9 14.6 18.7 18.4 20.0 43.5 23.9 22.3 17.0 21.5 13.0 41.4 31.4 19.4 18.2 33.1 13.0 42.1 30.0 19.2 20.7 11.0 21.9 25.5 17.9 13.5 16.3 21.9 38.0 12.2 17.5 21.2 46.1 2.8 22.5 10.2 14.0 22.2 17.8 8.6 7.2 1.8 3.9 5.2 5.7 4.1 14.6 23.4 32.5 11.7 13.7 14.7 21.0 14.5 20.2 13.6 13.4 10.2 12.2 8.9 33.0 18.6 17.4 19.1 33.3 20.6 0.1 8.9 19.7 12.9 14.0 18.7 0.0 9.4 10.0 16.4 17.0 24.0 40.1 19.8 0.2 18.2 25.5 0.2 0.2 12.6 26.2 13.1 17.8 0.4 28.7 33.5 12.9 16.1 22.7 7.3 14.7 17.2 0.3 24.2 13.4 25.3 15.8 16.3 0.0 0.1 0.9 17.4 0.1 18.1 1.8 3.9 0.0 0.3 1.6 0.0 6.8 0.8 0.1 5.3 8.6 5.7 2.0 1.7 5.2 0.9 7.2 0.2 4.1 36.0 42.3 20.5 40.8 43.5 23.9 41.4 31.4 30.0 46.1 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7;brain: 65.2" "Cell line enhanced" "Detected in many" "Daudi: 37.0;REH: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 202.9;basal ganglia: 236.9;cerebral cortex: 189.7;hippocampal formation: 443.3;olfactory region: 185.5" "Low region specificity" "Detected in many" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" 84000 "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favourable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favourable (5.11e-4)" "unprognostic (3.33e-3)" 7.2 4.7 20.4 24.3 30.0 46.7 4.9 65.2 48.3 5.4 14.5 7.8 5.0 16.6 4.3 4.7 7.9 6.8 6.4 4.7 30.5 7.0 6.8 5.0 11.5 35.6 4.3 25.4 2.4 5.4 5.2 5.3 4.1 3.9 10.1 11.9 8.3 12.6 6.7 2.2 15.1 18.4 5.5 4.8 32.0 10.8 4.3 3.7 37.8 5.6 2.9 35.4 13.0 6.0 26.9 18.7 24.0 25.8 14.7 19.0 21.5 10.9 3.0 0.8 0.9 23.5 1.7 6.4 0.8 0.5 0.6 0.8 2.9 6.3 37.0 1.2 1.7 10.1 0.3 9.2 0.3 2.5 0.2 7.6 2.9 0.5 4.8 8.2 13.8 12.7 13.8 0.8 5.3 0.3 8.9 25.7 0.6 1.1 14.0 16.5 0.6 0.8 41.0 0.2 25.3 2.6 8.6 5.8 1.0 3.9 2.7 1.4 3.3 21.2 5.2 0.4 0.8 0.7 0.3 20.7 8.9 20.0 1.6 17.8 0.7 22.3 23.7 18.0 19.0 22.4 12.5 25.5 9.6 13.3 18.7 26.9 12.1 14.2 24.0 14.7 25.8 6.2 9.5 21.5 20.4 30.0 65.2 48.3 30.5 7.0 4.3 25.4 3.9 3.7 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537370 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.0;intestine: 24.2;skin 1: 24.2" "Cell line enhanced" "Detected in some" "A-431: 11.3;CAPAN-2: 21.8;HaCaT: 17.7;hTCEpi: 24.0;RT4: 13.8;T-47d: 13.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavourable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.7 0.0 0.4 5.3 0.4 0.0 1.7 0.4 0.4 7.6 18.1 0.5 0.8 13.6 0.6 0.5 44.0 0.0 11.7 0.4 0.4 0.0 0.8 1.7 1.1 0.4 0.4 0.4 0.4 1.4 0.0 0.4 0.6 0.4 2.2 7.4 0.4 7.6 0.4 0.4 24.2 24.2 0.9 0.4 0.4 12.5 0.4 0.4 0.4 0.4 18.9 17.2 6.5 15.0 1.3 4.5 1.2 2.4 0.3 1.9 0.9 11.3 1.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 21.8 0.0 3.9 0.0 17.7 0.0 0.0 0.0 2.8 0.2 0.0 4.5 0.0 0.0 0.0 3.6 0.0 24.0 0.0 0.1 0.0 0.1 1.3 0.1 6.3 0.0 0.1 0.1 8.2 0.0 0.6 0.2 0.0 13.8 0.2 1.2 1.3 4.3 0.0 13.3 0.8 0.1 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.2 0.2 0.6 1.2 2.4 0.4 0.5 1.7 1.9 1.2 0.4 0.1 4.5 1.3 0.4 0.6 1.2 0.3 1.3 0.3 0.5 0.9 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248069-25298014 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 101.9" "Cell line enhanced" "Detected in all" "PC-3: 70.3;SK-MEL-30: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol 16000000 Cytosol "HPA031067: " "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavourable (4.37e-4)" "prognostic unfavourable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.43e-4)" 19.0 11.3 24.2 12.1 22.9 6.1 28.4 38.3 34.8 14.3 47.0 21.5 19.0 12.5 15.9 13.8 49.6 14.1 21.1 72.5 21.1 21.3 13.5 4.4 14.8 8.1 22.9 24.7 11.9 9.7 8.0 18.2 6.2 28.0 42.2 33.8 11.0 58.4 52.0 5.0 23.9 13.1 101.9 17.8 8.2 24.1 14.5 17.4 9.5 21.1 8.4 10.3 56.7 14.8 4.5 11.2 5.2 16.8 8.1 10.6 16.0 5.2 37.6 6.8 6.6 17.4 32.8 5.0 10.6 13.9 8.9 7.5 8.4 6.5 6.2 12.5 14.1 21.1 7.6 28.2 4.9 3.5 4.7 5.0 3.1 14.4 20.6 7.3 7.0 19.0 26.5 22.7 33.6 11.4 2.7 15.8 12.5 14.5 7.3 5.7 6.1 70.3 5.6 12.3 8.2 48.9 9.6 10.2 6.3 7.2 12.8 88.2 8.9 4.7 25.0 10.6 6.4 11.3 21.5 6.1 9.5 2.4 11.9 5.8 57.6 2.6 10.2 5.2 8.5 15.5 8.3 4.5 6.8 7.5 11.2 4.2 8.8 10.6 2.5 8.1 16.8 5.5 7.5 16.0 24.2 22.9 38.3 34.8 21.1 21.3 22.9 24.7 28.0 17.4 PYGL ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944736 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 56.1;HMC-1: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 36.0;neutrophil: 41.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" 17000000 "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavourable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 47.6 9.9 4.9 9.7 6.8 40.0 28.1 1.3 3.9 17.2 10.1 3.0 23.7 1.7 10.9 7.3 24.8 7.8 5.5 15.0 3.9 3.4 6.8 58.8 19.6 25.6 6.5 1.6 15.4 4.1 12.5 3.7 23.3 5.3 11.4 10.3 17.8 11.8 55.2 7.1 15.3 3.5 11.2 8.7 38.8 4.5 6.8 5.4 2.4 7.1 9.1 7.3 18.4 24.3 0.0 7.3 41.4 13.8 0.1 0.0 5.5 28.3 8.0 2.1 13.2 9.8 11.8 23.0 5.7 4.8 15.7 24.0 21.1 3.6 0.0 11.1 33.8 56.1 21.4 28.8 27.3 0.1 9.0 5.4 12.8 16.4 17.6 20.6 62.0 25.1 11.8 21.3 9.0 13.9 2.2 0.1 11.1 28.3 0.0 28.4 7.9 29.7 0.5 7.3 1.1 21.8 19.0 0.9 0.9 25.8 9.0 0.3 4.2 40.4 0.6 6.1 10.2 11.4 18.3 0.2 0.0 0.0 5.6 21.3 3.2 11.3 13.8 36.0 0.0 6.3 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 41.4 0.1 3.9 0.3 0.0 5.5 4.9 6.8 1.3 3.9 3.9 3.4 6.5 1.6 5.3 5.4 PYGM ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64760297 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 37 "skeletal muscle: 572.6;tongue: 172.6" "Cell line enhanced" "Detected in some" "HSkMC: 8.2;NB-4: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced 12000000 "HPA056003: " "unprognostic (3.33e-1)" "unprognostic (6.03e-3)" "unprognostic (3.87e-4)" "unprognostic (1.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (2.92e-1)" "unprognostic (3.88e-1)" "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (6.33e-6)" "unprognostic (3.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-2)" "unprognostic (5.68e-2)" 6.4 0.8 2.2 0.7 3.0 0.7 0.8 1.1 3.1 0.9 2.1 1.8 0.7 0.7 1.1 4.6 7.1 1.5 0.9 5.5 2.9 1.0 0.7 0.6 0.7 0.7 1.5 1.1 0.7 0.7 0.6 0.3 0.7 6.6 2.5 0.9 1.6 7.9 2.8 572.6 0.6 0.8 2.5 4.1 0.7 0.8 0.9 1.8 0.0 1.2 172.6 6.4 1.5 0.6 1.9 0.3 9.9 0.0 1.6 0.3 0.2 0.2 0.1 1.7 0.2 1.2 1.7 0.3 0.2 0.1 0.3 0.0 0.7 0.7 1.3 0.5 0.0 0.3 0.5 0.1 0.1 1.4 0.3 0.8 0.3 0.0 0.7 0.8 0.3 8.2 0.6 0.6 0.2 0.0 1.5 1.5 0.0 2.1 1.4 4.7 1.7 0.2 0.9 1.5 0.3 0.0 0.2 0.5 0.1 0.6 0.7 0.9 0.7 0.9 0.6 0.0 0.9 0.3 0.1 2.3 2.8 1.0 0.0 0.2 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.0 1.9 0.0 0.1 0.2 1.6 0.0 0.3 0.3 0.2 2.2 3.0 1.1 3.1 2.9 1.0 1.5 1.1 6.6 1.8 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37344574-37373322 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.6;blood: 137.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.5;SCLC-21H: 23.8;SK-MEL-30: 80.0;U-266/84: 62.5" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "neutrophil: 137.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 3.2 77.6 4.3 5.4 5.8 17.0 6.4 1.2 11.6 9.2 11.3 2.2 1.5 2.2 6.2 43.7 2.4 1.9 5.5 2.9 6.7 17.9 12.4 1.3 6.1 7.4 3.9 5.0 1.4 5.5 9.6 31.6 7.8 5.9 3.5 4.2 21.2 14.7 2.8 4.0 14.2 2.3 3.4 3.0 8.5 3.4 2.6 0.5 2.3 1.8 4.4 4.8 7.0 2.9 0.2 10.7 137.6 29.7 0.0 0.0 12.1 0.1 7.9 0.0 0.0 1.0 2.6 0.0 1.0 17.5 1.3 2.1 0.5 1.4 0.0 0.6 5.9 0.0 0.5 0.0 2.1 0.1 15.3 3.5 0.0 1.5 0.1 0.5 0.0 1.5 0.0 9.7 0.0 5.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.0 0.0 0.1 8.6 2.1 23.8 0.0 1.3 0.0 80.0 0.1 0.5 3.7 0.0 0.0 0.0 0.1 3.0 62.5 0.0 5.3 0.0 0.0 0.6 29.7 0.2 0.0 3.4 0.0 0.2 0.0 0.0 10.7 0.1 0.0 0.0 137.6 0.0 0.3 0.2 0.0 12.1 4.3 5.8 1.2 11.6 6.7 17.9 3.9 5.0 5.9 0.5 QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692483-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040797 Approved Supported "Golgi apparatus" "Golgi apparatus" "HPA040797: AB_10794148" "unprognostic (6.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.09e-1)" "unprognostic (7.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-1)" "unprognostic (8.41e-3)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.69e-1)" "unprognostic (3.14e-2)" "unprognostic (6.05e-2)" "prognostic unfavourable (2.15e-8)" "unprognostic (1.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.02e-2)" "unprognostic (5.71e-2)" 6.3 10.2 8.2 9.6 10.2 13.3 7.8 10.3 13.5 9.6 11.6 6.3 9.6 11.2 7.6 10.2 11.4 8.6 15.9 5.0 8.9 10.8 7.9 18.2 11.8 10.7 7.3 8.0 11.2 10.7 9.5 10.8 9.6 10.8 10.8 9.5 7.7 13.5 10.8 3.2 12.4 7.9 6.1 6.4 12.9 9.5 5.9 5.0 9.7 17.1 7.5 13.2 11.9 6.4 3.1 3.6 5.1 2.1 4.1 4.3 1.2 10.1 6.9 5.5 22.6 5.5 2.6 4.2 6.6 9.5 9.4 15.5 7.3 7.6 12.4 7.2 7.2 6.4 6.8 7.3 5.8 3.5 8.7 4.6 8.9 14.5 9.3 4.6 8.0 4.8 8.9 7.8 11.4 8.3 6.1 21.8 5.8 8.0 4.3 5.5 3.9 3.9 5.1 4.0 9.9 10.7 4.8 5.2 3.2 6.7 5.5 11.2 4.2 7.2 5.3 4.8 8.0 5.0 6.3 20.4 12.1 11.7 16.6 10.6 3.8 3.1 2.0 0.9 4.3 2.1 3.0 3.1 2.1 1.4 2.4 2.8 2.1 2.8 5.1 4.1 1.3 3.6 1.4 1.2 8.2 10.2 10.3 13.5 8.9 10.8 7.3 8.0 10.8 5.0 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29679008-29698699 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.2" "Cell line enhanced" "Detected in many" "EFO-21: 96.7;Hep G2: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 7.7" "Group enriched" "Detected in many" 4 "dendritic cells: 4.6;monocytes: 7.7" HPA011887 Approved "Intracellular and membrane" 230000 "HPA011887: AB_2668555" "prognostic unfavourable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavourable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 3.2 36.4 6.1 3.0 5.2 1.1 2.4 1.6 5.8 17.9 10.8 4.4 43.3 20.0 12.7 44.3 1.3 14.9 4.9 11.3 4.9 7.5 40.1 61.2 4.7 2.9 7.9 7.5 15.3 22.9 6.1 2.6 24.3 10.0 4.4 5.2 12.6 15.0 19.4 1.5 1.6 24.1 4.7 6.4 5.3 2.7 3.1 2.6 3.7 2.2 0.3 2.1 5.9 5.1 0.1 4.6 1.2 7.7 0.5 1.4 2.2 0.1 0.2 9.2 10.1 1.5 3.8 22.6 0.9 0.9 1.5 1.8 23.1 16.5 0.4 96.7 1.8 0.1 3.1 0.1 0.8 0.1 2.1 4.7 0.3 40.3 8.8 0.6 1.9 12.0 0.2 0.8 0.0 0.0 11.8 0.5 0.0 22.5 3.0 16.4 28.1 0.0 13.0 2.8 9.1 8.4 0.7 7.4 15.1 0.0 26.3 19.3 19.6 21.1 0.1 0.4 3.8 0.1 0.0 0.3 0.7 3.0 0.7 1.7 1.5 0.0 3.7 0.4 1.3 4.7 1.4 0.1 0.9 1.0 4.6 0.1 0.1 0.7 1.2 0.5 7.7 2.6 0.8 2.2 6.1 5.2 1.6 5.8 4.9 7.5 7.9 7.5 10.0 2.6 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria Mitochondria "HPA042695: , HPA048651: , HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favourable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favourable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favourable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavourable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 14.0 18.4 20.6 13.4 29.1 14.2 11.5 18.0 21.3 11.3 14.5 13.3 19.4 12.8 15.3 11.6 14.6 15.8 13.5 19.5 19.7 13.1 11.8 18.9 8.4 13.5 22.9 19.3 22.1 33.9 5.8 12.0 9.8 19.9 13.7 6.6 10.5 26.6 12.7 20.5 12.6 14.2 13.3 12.7 11.5 12.5 5.0 22.2 5.3 19.0 11.9 10.3 12.0 10.3 19.6 19.1 0.9 14.4 18.5 18.8 10.4 17.1 13.9 6.6 19.3 6.9 8.4 8.6 8.8 7.9 10.3 10.2 11.0 6.6 19.4 21.7 5.0 11.6 6.0 10.6 3.4 11.4 8.3 12.8 5.6 23.3 12.1 18.9 11.3 12.4 9.1 6.7 9.8 10.5 14.0 22.4 5.1 26.9 16.3 23.7 17.4 21.5 17.2 8.8 30.0 8.4 11.0 21.5 9.3 13.5 14.8 11.5 9.4 8.0 8.1 15.9 8.8 25.4 20.5 24.7 19.0 9.5 8.6 23.1 19.2 0.9 8.3 0.2 15.1 14.4 18.8 19.6 16.3 13.1 16.4 19.0 17.5 13.9 0.6 18.5 7.3 19.1 17.7 10.4 20.6 29.1 18.0 21.3 19.7 13.1 22.9 19.3 19.9 22.2 RABGGTA PTAR3 ENSG00000100949 "Rab geranylgeranyltransferase alpha subunit" Q92696 14 24265538-24271739 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043488 Approved Enhanced Nucleoplasm Nucleoplasm "HPA043488: AB_10794887" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (2.61e-3)" "unprognostic (1.13e-1)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (5.78e-2)" "unprognostic (3.89e-2)" "unprognostic (7.11e-2)" "unprognostic (3.12e-2)" "unprognostic (1.12e-1)" "prognostic favourable (5.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.84e-1)" "prognostic favourable (1.51e-4)" "unprognostic (2.01e-1)" 6.9 9.9 8.6 7.1 9.4 8.7 7.5 9.4 16.2 8.2 9.8 8.4 13.6 7.2 6.4 11.6 37.2 12.3 8.1 10.9 6.9 8.0 12.5 15.0 10.6 10.7 7.7 8.5 8.0 16.4 15.7 10.2 14.1 10.6 8.0 8.0 7.2 12.8 9.2 11.1 13.3 12.1 6.9 6.1 11.5 9.4 11.3 7.0 7.3 9.4 20.3 18.2 8.4 11.4 6.5 12.7 6.7 16.8 6.9 6.3 6.3 3.5 5.9 2.3 3.2 3.7 6.8 12.5 5.3 5.1 8.6 7.5 6.0 5.2 5.4 3.9 6.5 6.9 2.8 12.2 3.5 6.8 7.2 3.1 5.0 20.6 7.0 6.6 11.9 7.3 14.0 4.2 5.7 7.1 2.7 4.2 6.6 15.3 3.5 4.9 1.4 8.6 3.1 2.1 3.8 7.8 6.8 6.1 3.6 4.0 8.3 4.3 4.1 4.7 5.2 4.1 3.0 1.8 2.8 5.7 4.3 3.4 2.8 4.2 6.3 3.1 10.0 6.7 5.9 16.8 5.1 6.5 5.7 5.1 12.7 4.2 5.0 4.4 2.6 6.9 12.4 4.0 6.3 6.3 8.6 9.4 9.4 16.2 6.9 8.0 7.7 8.5 10.6 7.0 RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase beta subunit" P53611 1 75786197-75795079 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavourable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" 19.4 31.8 20.2 25.3 20.1 8.7 23.5 25.8 24.2 19.4 18.8 16.8 14.8 18.6 20.9 14.1 15.7 15.6 12.0 27.2 19.1 20.4 40.7 35.8 17.4 13.1 26.3 14.8 18.5 33.2 12.3 26.4 17.3 20.5 15.6 16.2 13.7 25.0 15.8 33.5 9.5 14.5 13.1 29.4 19.0 14.3 11.9 18.0 21.3 17.3 21.6 34.4 12.4 13.3 10.6 12.8 7.6 11.5 6.3 10.7 4.4 17.0 9.7 17.7 6.9 22.3 25.7 10.3 23.3 17.4 22.4 17.9 22.1 4.2 14.4 23.9 12.9 10.6 43.3 18.8 31.6 14.8 11.6 12.4 16.4 37.2 27.6 16.6 7.6 17.1 42.6 20.0 23.1 18.2 20.7 15.0 25.1 7.4 14.0 19.8 14.1 16.7 11.5 26.2 6.6 17.1 9.4 9.6 9.3 5.3 30.1 54.2 5.9 17.0 17.6 14.2 16.1 33.2 44.6 10.1 29.5 10.3 16.4 13.5 6.2 7.6 7.7 4.5 8.8 11.5 10.3 10.6 8.9 8.1 12.8 7.1 10.5 10.7 1.3 6.3 8.0 12.0 8.0 4.4 20.2 20.1 25.8 24.2 19.1 20.4 26.3 14.8 20.5 18.0 RAD18 RNF73 ENSG00000070950 "RAD18, E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA006716: , HPA006724: , HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavourable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavourable (3.73e-4)" "prognostic unfavourable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 6.2 5.7 7.4 5.6 12.7 7.9 9.5 16.4 11.4 5.5 6.6 3.9 5.4 17.7 6.5 3.7 7.6 4.9 5.6 4.4 4.7 3.3 4.3 5.7 5.9 7.6 8.4 6.9 7.1 4.2 3.4 6.9 6.9 5.7 7.4 9.0 3.5 7.5 3.5 3.7 8.5 10.5 6.0 7.8 8.5 5.1 9.5 9.8 16.6 6.7 4.7 7.5 6.1 6.8 3.7 6.3 8.7 3.0 4.3 5.5 1.5 9.7 9.3 7.8 4.6 1.9 4.2 9.5 15.5 5.3 15.0 10.3 8.4 6.3 12.1 3.0 8.8 3.4 8.2 8.0 15.3 7.4 10.3 10.3 9.3 5.0 1.2 13.5 8.9 1.5 2.9 14.8 10.1 4.8 10.9 12.0 13.0 11.3 13.7 9.6 10.8 17.1 10.9 8.6 9.5 4.3 7.5 3.2 7.4 6.9 6.6 5.0 6.9 6.0 4.0 12.4 6.8 10.6 13.2 6.1 9.3 26.3 9.2 15.0 9.1 7.4 2.7 8.7 3.0 3.0 5.5 3.7 4.0 5.2 3.4 3.7 4.3 3.2 1.2 4.3 1.8 6.3 5.0 1.5 7.4 12.7 16.4 11.4 4.7 3.3 8.4 6.9 5.7 9.8 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.1 17.4 26.6 20.5 23.1 18.7 53.5 23.1 39.2 30.6 34.8 13.6 12.5 15.9 11.1 35.8 9.7 28.0 20.5 31.9 27.7 21.9 21.4 21.0 12.6 23.4 20.8 20.3 17.2 20.7 31.5 25.6 21.9 15.5 41.8 29.5 25.9 26.7 15.3 27.0 23.7 21.6 23.4 20.0 18.3 22.9 8.3 17.5 18.9 18.3 12.3 30.4 27.5 15.7 21.1 20.1 17.6 25.7 32.6 51.8 34.2 18.2 24.3 22.4 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510709-36593156 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "lymphoid tissue: 462.4" "Group enriched" "Detected in some" 110 "MOLT-4: 65.8;REH: 62.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043939 Supported Nucleoplasm Nucleoplasm "HPA043939: " "unprognostic (7.35e-2)" "unprognostic (1.57e-3)" "unprognostic (8.75e-2)" "unprognostic (3.44e-1)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "unprognostic (2.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (5.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.16e-9)" "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-4)" "unprognostic (1.53e-1)" 0.7 2.3 0.5 0.5 0.5 7.4 0.7 0.5 0.5 0.5 0.6 0.5 0.5 1.2 0.5 1.3 0.5 0.6 0.5 0.6 0.5 0.2 2.4 1.2 0.8 0.5 0.5 0.5 0.6 1.1 1.9 0.5 0.8 0.5 0.5 0.4 0.5 1.5 0.5 0.5 0.2 1.5 0.5 0.5 4.4 0.8 0.9 0.5 462.4 4.5 0.5 0.8 0.7 0.5 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 65.8 0.0 0.5 0.0 62.9 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.5 0.5 0.5 0.5 0.2 0.5 0.5 0.5 0.5 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA replication, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: , HPA043544: " "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 15.1 17.6 17.2 14.0 16.4 81.4 17.9 33.0 15.7 17.8 18.8 16.3 19.8 10.2 23.2 18.7 15.3 21.2 17.6 14.7 15.0 13.2 13.1 15.8 15.7 18.1 18.7 12.2 27.2 14.4 20.7 23.1 73.9 15.4 18.2 14.4 18.4 13.7 14.7 19.2 19.2 16.4 18.4 19.2 18.6 16.4 25.1 18.7 24.3 18.6 11.8 15.5 17.9 17.9 3.8 6.9 8.5 3.7 6.5 4.2 1.0 17.6 9.2 21.8 22.6 16.7 17.4 23.6 14.3 13.2 13.1 14.2 10.2 14.3 24.5 10.8 12.1 17.0 23.3 12.5 21.7 13.4 18.1 21.1 26.5 29.0 13.0 28.0 12.6 15.1 17.4 17.0 20.1 18.7 26.5 22.4 15.1 18.1 22.6 25.3 25.0 8.8 31.1 22.1 21.6 12.6 15.8 17.5 15.3 20.1 18.1 25.3 14.1 24.9 16.2 16.3 12.0 14.0 15.3 20.0 19.8 30.9 13.1 18.6 13.4 8.5 2.3 3.7 4.0 3.7 4.2 3.8 4.1 2.8 1.6 3.8 3.5 4.0 5.0 6.5 2.1 6.9 3.1 1.0 17.2 16.4 33.0 15.7 15.0 13.2 18.7 12.2 15.4 18.7 RBCK1 "C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4" ENSG00000125826 "RANBP2-type and C3HC4-type zinc finger containing 1" Q9BYM8 20 407498-430966 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.94e-2)" "unprognostic (2.50e-1)" "unprognostic (1.62e-2)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.92e-1)" "unprognostic (1.54e-3)" "unprognostic (1.15e-2)" "unprognostic (7.89e-2)" "unprognostic (3.44e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-2)" "prognostic unfavourable (7.41e-9)" "unprognostic (5.87e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-2)" "unprognostic (2.39e-3)" 24.6 36.4 18.8 30.7 23.9 24.2 26.0 40.2 18.8 21.4 34.0 25.4 22.5 31.9 25.7 29.7 27.6 23.5 31.4 23.2 18.6 15.1 28.1 53.0 31.3 29.8 27.2 19.1 28.9 28.7 22.9 28.9 30.5 19.1 28.0 17.5 18.2 39.7 30.4 21.7 27.1 43.3 20.9 20.9 34.6 25.0 18.2 24.3 44.4 26.2 18.5 19.4 23.4 23.3 17.5 26.6 50.3 30.1 18.5 23.2 18.4 18.3 22.1 5.4 9.6 10.0 13.3 14.6 11.6 13.7 14.1 18.6 12.8 18.4 9.2 14.8 16.7 16.6 6.6 37.1 4.8 6.7 9.4 8.1 5.1 35.1 45.7 8.0 6.0 19.7 63.6 10.2 44.3 13.6 7.8 14.1 9.3 8.4 15.1 21.4 5.4 22.5 11.5 7.0 10.4 18.2 13.8 11.2 11.4 8.3 29.7 36.1 17.2 16.0 9.3 13.1 7.6 9.0 13.0 12.7 15.5 9.9 7.1 16.0 9.6 17.3 18.9 30.1 23.2 24.8 16.8 17.5 18.3 23.1 16.3 16.0 15.2 17.6 50.3 18.5 30.1 26.6 19.5 18.4 18.8 23.9 40.2 18.8 18.6 15.1 27.2 19.1 19.1 24.3 RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781364-27891098 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 10.2;RPTEC TERT1: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019725, HPA028285" Enhanced Approved Cytosol Cytosol "HPA019725: AB_1856105, HPA028285: AB_10601480" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-2)" "unprognostic (5.54e-3)" "unprognostic (4.15e-3)" "unprognostic (2.44e-1)" "unprognostic (1.43e-2)" "unprognostic (4.77e-2)" "unprognostic (2.45e-1)" "unprognostic (5.35e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (9.27e-2)" 14.4 22.2 2.5 2.4 5.2 4.1 2.2 2.1 4.1 2.6 3.0 1.7 4.9 12.4 4.7 4.7 3.1 7.4 10.7 3.5 3.7 4.3 15.1 22.6 10.4 0.8 3.0 2.4 24.2 2.4 3.5 10.3 6.2 12.3 6.9 2.4 2.2 1.4 16.8 7.6 1.0 11.8 3.8 4.7 1.7 1.6 4.8 1.4 0.3 4.5 2.8 1.1 4.8 12.0 5.8 5.1 5.6 3.8 4.9 6.5 3.4 3.0 2.0 0.3 0.4 0.4 0.7 2.0 0.8 0.6 0.4 0.6 4.7 1.5 1.0 10.2 1.7 1.2 0.2 1.0 0.8 0.4 0.2 0.1 0.5 4.0 1.5 0.8 0.2 1.0 1.7 2.6 3.6 0.6 0.1 1.3 2.0 4.0 0.6 2.2 0.0 1.7 0.9 0.2 0.7 21.6 0.2 0.8 1.2 2.9 3.9 1.7 1.7 4.5 0.1 0.7 0.5 1.8 1.2 6.6 7.7 2.0 1.9 3.0 0.1 5.6 3.8 1.9 3.0 1.6 6.1 5.8 4.0 6.5 5.1 4.6 4.2 3.6 5.6 4.9 0.8 0.8 5.8 3.4 2.5 5.2 2.1 4.1 3.7 4.3 3.0 2.4 12.3 1.4 RBX1 "BA554C12.1, RNF75, ROC1" ENSG00000100387 "Ring-box 1" P62877 22 40951347-40973309 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003038 Supported Nucleoplasm Nucleoplasm "HPA003038: AB_1079827" "unprognostic (2.34e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.60e-3)" "unprognostic (2.30e-1)" "unprognostic (2.92e-2)" "unprognostic (1.82e-3)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "prognostic favourable (6.63e-4)" "unprognostic (5.01e-3)" "unprognostic (2.19e-1)" "unprognostic (4.99e-3)" "unprognostic (2.22e-2)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" 24.1 27.9 41.6 22.2 35.3 37.6 32.9 28.0 35.7 23.0 22.7 27.4 15.8 18.4 19.4 43.7 27.6 21.2 16.6 39.2 38.3 37.4 34.2 28.3 23.6 28.1 40.4 22.3 18.5 15.6 12.3 19.5 54.1 32.4 20.3 23.9 22.1 21.3 20.8 46.5 21.8 23.0 23.2 45.2 26.4 21.4 16.4 24.8 31.7 31.1 37.4 34.4 19.5 19.4 33.4 60.7 32.2 41.5 23.9 38.5 62.6 33.1 19.0 35.9 17.8 25.5 30.5 20.2 26.7 24.6 40.3 35.7 30.7 16.0 29.1 18.1 26.2 19.0 34.0 30.6 42.7 33.8 54.2 18.0 27.8 37.4 21.9 43.9 23.4 25.2 24.8 29.1 21.1 34.1 21.2 29.6 35.5 40.6 26.4 50.7 19.7 20.0 34.7 24.9 36.6 46.0 21.5 16.9 11.0 23.5 23.6 23.9 20.3 30.3 22.6 24.6 25.4 20.6 25.4 25.2 23.1 43.1 30.8 22.4 27.3 32.2 37.2 29.9 24.7 37.0 23.1 33.4 30.9 26.0 37.6 29.4 27.0 29.2 12.6 23.9 41.5 60.7 38.5 62.6 41.6 35.3 28.0 35.7 38.3 37.4 40.4 22.3 32.4 24.8 RC3H2 "FLJ20301, FLJ20713, MNAB, RNF164" ENSG00000056586 "Ring finger and CCCH-type domains 2" Q9HBD1 9 122844556-122905341 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "Repressor, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042863, HPA062144" Approved Enhanced Vesicles Vesicles "HPA042863: , HPA062144: " "unprognostic (6.05e-2)" "unprognostic (7.87e-2)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "prognostic favourable (5.50e-4)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" 16.4 10.7 25.4 14.1 28.8 30.6 14.1 18.7 27.6 17.1 13.0 10.5 14.4 11.0 14.6 9.7 16.5 12.2 12.6 15.7 18.1 11.2 15.0 14.8 16.2 19.2 12.3 25.3 14.7 9.7 19.0 16.2 16.3 12.6 11.5 13.1 9.4 13.2 13.9 16.1 13.8 13.0 16.3 14.4 15.2 12.8 12.8 13.2 18.9 15.0 11.5 18.8 14.1 13.7 8.6 9.6 12.4 10.4 4.9 8.9 3.7 9.8 14.3 19.1 10.3 10.2 12.1 10.6 12.6 13.8 14.9 13.0 17.3 10.4 16.5 10.3 16.8 23.1 20.4 14.8 16.4 7.6 8.1 9.4 25.8 11.4 13.4 11.1 15.1 11.6 14.4 14.5 20.6 20.4 13.2 12.1 18.8 13.2 10.9 7.8 9.5 13.3 11.0 31.6 10.6 14.5 7.8 22.5 15.6 22.3 13.8 11.4 16.6 9.4 20.2 11.5 9.6 15.6 22.4 8.5 13.8 18.0 13.1 9.9 12.9 12.4 6.6 8.5 8.9 10.4 7.3 6.5 7.3 8.9 5.8 8.6 7.0 6.8 11.8 4.9 9.3 9.6 7.1 3.7 25.4 28.8 18.7 27.6 18.1 11.2 12.3 25.3 12.6 13.2 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favourable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favourable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favourable (7.89e-5)" 8.8 12.1 15.7 9.9 20.1 15.6 17.8 20.7 16.8 10.2 12.7 9.8 8.7 9.0 11.0 7.5 8.4 12.9 7.2 17.6 14.1 16.2 17.1 12.5 10.4 12.2 15.9 15.7 16.2 10.6 14.9 13.0 10.5 17.1 12.0 14.2 7.7 12.3 11.3 29.7 5.9 9.2 12.4 16.7 12.2 10.3 13.4 15.4 14.9 20.3 8.0 12.7 9.7 12.1 4.4 7.4 18.9 8.8 4.6 7.4 4.3 6.0 3.1 9.4 8.7 9.9 8.7 5.4 4.1 9.6 8.5 10.0 8.6 7.5 10.1 7.8 5.9 3.6 23.8 7.2 13.0 8.2 7.8 13.1 5.9 11.0 8.5 17.6 7.2 8.0 9.1 9.7 9.2 17.1 12.0 10.3 19.8 9.8 16.1 7.1 15.6 5.5 8.7 22.1 8.5 13.2 10.4 14.5 8.0 6.7 15.8 17.4 8.9 8.0 6.7 5.6 5.6 5.0 6.8 10.9 7.8 14.3 6.8 12.5 8.8 18.9 8.8 8.5 4.3 5.2 7.4 4.4 5.3 5.0 7.4 2.2 3.9 5.5 3.7 4.6 4.7 3.8 5.2 4.3 15.7 20.1 20.7 16.8 14.1 16.2 15.9 15.7 17.1 15.4 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077027-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 63.9" "Cell line enhanced" "Detected in some" "MCF7: 17.6;NB-4: 11.6;SH-SY5Y: 89.7;THP-1: 26.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.1;monocytes: 6.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "midbrain: 95.5" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" 260000 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavourable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 15.2 1.1 1.8 1.3 0.7 1.2 4.1 9.0 1.9 3.1 0.9 1.1 1.5 0.9 0.6 1.2 0.7 1.0 1.2 1.5 5.8 1.0 11.7 0.7 0.8 17.5 1.2 0.8 1.3 63.9 6.3 0.8 16.8 2.2 1.5 2.8 13.6 2.0 4.5 1.1 2.6 1.1 2.8 0.6 2.1 2.0 0.0 0.1 0.8 5.1 0.6 1.9 1.4 0.2 2.1 0.0 6.7 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 11.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 89.7 0.0 0.0 0.0 1.2 26.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.7 2.1 0.3 0.4 1.1 1.3 4.1 9.0 1.5 5.8 17.5 1.2 16.8 0.0 REV3L "POLZ, REV3" ENSG00000009413 "REV3 like, DNA directed polymerase zeta catalytic subunit" O60673 6 111299028-111483715 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 39.4;ASC TERT1: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064853, HPA069382" Uncertain Approved Nucleoplasm Nucleoplasm "HPA064853: , HPA069382: " "unprognostic (5.54e-2)" "unprognostic (2.06e-1)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (8.59e-3)" "unprognostic (4.42e-2)" "unprognostic (1.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.17e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.34e-2)" "unprognostic (2.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-3)" 21.0 7.1 7.8 8.8 7.3 7.3 15.1 26.0 7.6 31.7 11.0 5.8 14.1 5.4 34.5 18.5 7.6 12.2 7.4 7.1 6.5 6.1 6.5 6.4 10.8 6.3 5.4 5.8 11.3 8.1 7.8 15.1 10.2 6.8 11.4 7.4 8.3 6.9 16.3 17.1 8.2 7.0 18.0 6.9 7.1 8.6 10.3 6.7 10.2 9.2 7.2 5.5 18.3 16.2 5.1 2.8 6.0 2.9 1.7 4.6 1.0 4.6 2.9 5.7 8.6 39.4 30.0 6.2 6.6 10.8 3.6 5.9 5.2 2.8 10.2 4.8 9.5 4.8 8.4 3.7 6.2 5.9 4.6 6.8 7.5 7.0 5.5 7.0 4.1 19.1 3.3 6.7 10.5 6.6 8.6 6.5 7.0 4.3 8.3 1.5 2.0 4.9 5.4 6.3 3.3 2.7 5.8 7.5 6.0 8.2 3.0 7.0 3.8 7.6 7.6 5.4 5.1 25.5 7.5 6.8 8.0 9.1 5.3 5.5 7.1 1.9 1.7 3.3 3.3 1.3 4.6 2.8 2.5 3.0 1.7 5.1 1.6 2.8 6.0 1.7 2.9 2.8 1.9 1.0 7.8 7.3 26.0 7.2 6.5 6.1 5.4 5.8 6.8 6.7 RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 56.8" "Cell line enhanced" "Detected in all" "HDLM-2: 40.5;Karpas-707: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favourable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavourable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" 5.8 6.1 11.1 9.9 22.9 22.1 6.7 4.4 15.7 6.7 14.6 56.8 5.9 14.8 6.9 5.3 21.6 5.4 11.5 5.8 14.4 10.5 15.4 25.0 6.8 8.9 32.1 7.3 5.2 10.1 8.3 4.9 6.5 30.7 10.7 12.6 4.5 9.6 7.0 12.2 5.2 11.9 7.3 32.1 9.9 13.4 15.7 27.5 13.1 23.0 5.4 15.0 10.2 9.2 4.2 5.2 26.8 7.6 6.7 14.5 7.1 7.7 14.8 3.9 5.5 6.5 9.2 2.1 5.1 8.4 5.3 6.4 5.0 15.5 2.3 6.5 6.5 11.0 6.1 9.9 7.4 40.5 4.2 12.1 3.9 12.3 5.5 7.8 7.3 6.2 5.9 7.9 14.1 5.2 5.7 37.8 4.7 2.5 1.7 7.0 4.6 8.8 5.4 6.3 13.7 7.8 15.6 4.3 5.4 3.2 3.4 3.2 5.2 8.6 10.1 3.1 5.5 3.0 8.3 14.1 11.8 3.6 12.1 5.5 2.8 11.3 7.6 16.3 8.8 4.6 10.6 4.2 9.9 8.3 5.2 4.1 8.5 7.5 26.8 6.7 4.1 0.6 14.5 7.1 11.1 22.9 4.4 15.7 14.4 10.5 32.1 7.3 30.7 27.5 RFK "FLJ11149, RIFK" ENSG00000135002 "Riboflavin kinase" Q969G6 9 76385517-76394517 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023259, CAB033887, HPA057163" Approved Approved "Golgi apparatus" "Golgi apparatus" "CAB033887: AB_2178617, HPA023259: , HPA057163: " "unprognostic (1.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-3)" "unprognostic (8.61e-3)" "unprognostic (3.11e-1)" "unprognostic (1.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (4.61e-2)" "unprognostic (1.22e-3)" "unprognostic (3.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" 8.1 15.4 24.8 9.8 31.0 15.2 8.7 15.3 27.7 8.9 22.1 5.7 6.2 23.9 9.5 14.3 9.4 10.0 14.5 11.4 33.0 33.5 19.4 23.6 8.8 7.4 22.8 13.2 10.8 11.9 10.3 16.5 26.0 28.3 9.6 16.8 13.3 9.1 7.6 10.3 3.8 39.3 8.5 10.2 8.2 20.3 12.2 8.0 8.1 14.4 5.7 11.6 9.2 7.3 4.9 9.6 3.8 16.3 6.8 6.7 7.8 9.8 10.5 6.5 8.3 9.7 9.6 19.5 11.5 8.4 8.2 6.5 3.7 6.1 16.0 13.6 8.1 10.6 8.7 7.4 16.5 4.8 8.5 5.1 14.7 11.9 17.5 16.7 12.1 6.4 13.5 9.8 10.8 26.5 13.4 13.3 16.4 9.2 21.5 6.1 8.4 11.2 12.0 8.5 4.1 37.7 4.9 16.5 6.1 12.2 17.2 10.0 4.3 9.2 16.6 8.7 15.8 18.8 16.0 14.5 14.4 5.5 14.4 15.0 11.9 3.8 8.1 2.8 4.4 16.0 6.7 4.9 6.5 5.2 9.6 4.0 6.3 6.0 1.2 6.8 16.3 3.6 6.1 7.8 24.8 31.0 15.3 27.7 33.0 33.5 22.8 13.2 28.3 8.0 RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Supported Nucleoplasm 450000 Nucleoplasm "HPA011564: AB_1079803, HPA031673: " "unprognostic (4.17e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-3)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "prognostic favourable (4.81e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (4.14e-2)" 19.5 13.0 13.8 9.3 13.3 11.7 43.8 14.3 13.8 11.4 11.8 9.0 22.7 14.9 13.5 20.9 13.4 16.3 17.0 12.2 11.6 8.7 12.5 34.5 16.7 10.1 11.2 8.0 19.7 26.6 4.1 10.7 8.2 9.9 11.8 4.8 10.6 27.3 20.4 32.6 13.3 12.7 12.9 8.5 8.9 13.2 12.8 10.6 5.7 12.6 10.5 7.6 12.4 12.8 3.4 3.4 4.3 5.0 0.4 6.3 1.5 9.3 9.3 2.7 9.4 7.0 6.2 12.1 8.7 5.1 4.2 3.3 5.7 6.7 2.2 6.3 13.8 5.2 1.9 7.5 0.8 2.8 9.8 3.2 2.2 23.1 34.7 1.2 6.9 11.2 5.1 7.2 12.3 7.8 4.0 8.2 3.3 11.5 6.9 3.3 2.7 9.8 4.8 3.3 4.9 4.7 5.7 4.8 12.2 3.3 5.7 25.7 15.7 6.7 2.9 6.6 9.0 6.3 4.7 11.0 2.1 2.3 8.3 2.0 5.7 2.3 5.0 4.3 4.1 1.4 1.5 2.5 2.8 4.3 3.4 3.4 2.8 1.9 2.0 0.4 1.5 2.7 6.3 1.5 13.8 13.3 14.3 13.8 11.6 8.7 11.2 8.0 9.9 10.6 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621394-74666881 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA048258: , HPA075649: " "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 7.3 5.2 4.2 12.2 6.1 33.9 7.8 7.8 5.6 7.4 6.7 8.4 8.4 5.5 9.7 10.0 12.8 6.3 5.5 5.4 3.9 3.7 6.5 5.6 6.5 12.0 6.1 4.8 7.7 9.6 8.5 7.5 11.5 5.3 6.5 8.1 7.2 8.0 8.4 4.5 11.6 7.8 5.6 4.8 9.7 6.2 35.1 7.2 40.5 7.0 7.5 18.0 7.2 8.6 9.3 7.1 13.8 10.9 9.1 11.7 6.5 13.9 17.9 13.5 9.8 2.8 3.9 15.3 12.6 9.7 20.2 17.6 23.3 14.7 19.5 10.3 9.8 16.8 22.1 13.1 24.8 6.1 13.2 17.2 14.6 13.1 2.5 17.3 18.0 2.8 4.2 25.4 15.7 8.5 26.0 8.8 15.1 22.2 25.2 15.9 26.6 8.7 39.3 9.2 17.2 7.2 14.8 10.1 10.7 20.3 7.2 9.0 13.2 14.8 8.3 14.8 14.2 8.3 15.8 11.9 22.1 58.4 10.6 13.4 17.9 13.8 6.8 9.9 9.3 6.3 10.2 7.8 7.7 8.6 7.1 9.3 11.7 8.1 7.7 9.1 10.9 5.5 10.9 6.5 4.2 6.1 7.8 5.6 3.9 3.7 6.1 4.8 5.3 7.2 RING1 RNF1 ENSG00000204227 "Ring finger protein 1" Q06587 6 33208495-33212722 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008701 Supported Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA008701: AB_1079814" "unprognostic (2.12e-3)" "unprognostic (7.98e-2)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.91e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-1)" "unprognostic (4.75e-2)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.70e-2)" "unprognostic (1.62e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (2.13e-1)" "unprognostic (9.88e-2)" 26.7 22.6 17.8 15.9 21.3 12.0 14.6 27.6 24.2 22.2 17.6 22.0 21.0 18.2 31.9 17.3 14.5 18.8 21.4 14.4 17.3 18.2 19.3 21.6 16.8 14.5 24.0 15.4 25.0 18.3 24.0 34.0 14.9 17.0 21.8 7.6 20.0 19.0 20.5 18.0 21.7 19.5 22.9 18.5 23.2 24.1 16.9 20.8 25.5 29.3 13.1 14.3 13.9 17.1 1.2 2.2 0.8 1.5 0.2 2.2 0.2 4.2 3.5 4.2 4.0 4.2 1.4 9.7 11.1 6.8 4.5 4.6 3.8 3.1 6.9 4.6 4.4 7.6 3.6 3.3 3.2 8.5 2.9 8.3 5.8 7.1 9.6 4.7 6.8 0.0 3.4 4.0 7.5 1.6 11.9 5.3 4.7 0.0 0.3 3.7 1.9 4.6 4.5 6.9 7.6 5.0 3.7 8.3 5.2 4.0 4.3 11.5 4.9 8.3 2.3 5.0 3.8 0.0 9.1 6.0 6.2 6.6 3.7 4.3 3.1 0.0 1.5 0.8 2.2 0.4 0.4 1.1 0.7 1.0 0.7 1.2 1.7 0.9 0.3 0.2 0.5 2.2 0.4 0.2 17.8 21.3 27.6 24.2 17.3 18.2 24.0 15.4 17.0 20.8 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389496-7418037 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Approved "Nucleoli,Nuclear speckles,Cytosol" "Nucleoli, Nuclear speckles" Cytosol "HPA017866: , HPA051446: " "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavourable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 13.8 10.6 7.7 13.2 13.0 17.5 13.1 12.2 13.5 12.7 11.6 7.3 4.0 7.3 15.4 6.0 15.6 12.3 8.5 11.8 8.0 8.1 8.7 11.7 10.1 14.2 11.6 9.4 13.8 15.3 7.7 17.8 13.9 13.3 10.7 9.6 7.2 10.2 10.3 18.8 12.5 9.9 15.5 9.4 14.4 10.3 21.3 9.2 19.2 10.1 14.7 16.8 10.9 12.6 15.4 14.9 7.7 11.1 18.6 15.0 8.2 7.5 4.4 7.1 16.7 11.1 9.1 10.9 9.5 6.4 8.9 7.4 12.8 3.9 19.7 16.9 7.7 7.7 17.9 7.6 11.4 13.0 19.3 10.5 7.1 13.7 9.4 30.2 13.8 6.7 10.6 9.6 19.8 7.8 26.8 4.6 8.3 9.9 20.5 14.3 15.3 10.4 15.8 9.3 21.4 5.0 7.4 23.7 11.7 8.0 4.8 13.8 7.3 10.0 7.8 9.8 7.4 6.4 14.3 6.4 12.1 29.3 3.0 15.6 14.9 7.7 8.5 5.9 11.5 11.1 13.8 15.2 11.9 12.1 14.9 15.4 13.7 15.0 1.7 18.6 9.7 12.4 11.3 8.2 7.7 13.0 12.2 13.5 8.0 8.1 11.6 9.4 13.3 9.2 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 22.2 20.1 14.8 17.1 17.5 24.4 19.7 26.3 18.6 19.1 17.0 8.9 14.0 17.3 17.5 17.1 17.0 15.0 10.7 19.6 15.7 13.4 21.0 23.6 13.3 17.6 20.0 11.1 20.7 21.5 15.1 37.5 15.8 19.7 19.5 17.3 10.3 18.7 16.6 24.9 13.3 20.2 16.3 20.7 22.5 16.4 14.8 18.6 25.8 21.7 20.7 17.4 20.7 21.0 15.2 17.8 9.4 18.7 17.8 24.1 13.5 8.8 10.4 9.7 18.8 12.8 14.0 15.5 22.3 13.8 15.8 21.0 14.2 15.6 19.6 25.4 10.0 10.5 16.5 13.0 21.7 13.8 9.1 9.8 20.1 19.8 11.5 18.6 13.8 9.2 10.2 19.3 19.6 12.8 14.8 12.7 18.1 14.8 21.7 22.2 11.5 11.2 24.5 18.9 28.8 12.4 8.1 12.1 9.0 13.5 14.0 15.3 14.7 17.7 13.7 20.3 14.1 16.1 24.2 12.5 16.2 44.0 12.1 19.1 18.4 7.0 16.0 9.4 16.3 18.7 22.3 15.2 20.7 17.8 17.8 11.0 22.5 24.1 3.2 17.8 13.4 17.8 18.5 13.5 14.8 17.5 26.3 18.6 15.7 13.4 20.0 11.1 19.7 18.6 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23452823-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavourable (4.10e-4)" "prognostic unfavourable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 10.1 8.7 6.9 11.7 7.7 52.4 10.9 8.9 10.1 14.7 21.4 8.5 5.9 15.6 8.8 9.3 41.0 7.8 10.7 11.5 6.1 5.5 10.5 19.9 10.1 10.7 9.1 6.2 7.6 10.7 7.5 11.6 21.4 11.6 6.8 14.7 6.0 14.9 7.0 40.0 13.3 36.5 15.2 10.5 8.9 12.9 22.7 7.6 11.1 7.3 16.0 16.5 13.7 21.5 11.7 11.0 21.7 21.5 8.3 11.2 10.0 14.7 5.8 6.0 7.8 11.0 12.3 10.9 14.8 10.9 10.5 10.1 6.6 15.9 10.2 19.4 16.4 19.3 10.2 16.8 16.2 10.1 4.2 9.5 10.8 8.3 27.5 26.7 8.3 14.7 32.0 18.6 25.8 14.5 13.7 12.9 15.7 7.8 9.2 4.4 5.6 11.6 10.4 12.6 12.4 12.0 19.3 14.0 10.1 18.9 8.6 10.8 7.6 14.5 22.9 17.3 4.3 7.6 9.6 23.2 19.6 15.2 10.2 12.4 12.9 21.7 13.5 8.0 9.1 19.6 6.9 8.2 7.6 7.9 11.0 11.7 6.1 6.9 9.3 8.3 21.5 5.1 11.2 10.0 6.9 7.7 8.9 10.1 6.1 5.5 9.1 6.2 11.6 7.6 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063991-3115187 "Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Enhanced "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favourable (6.71e-4)" 24.5 12.0 6.9 15.7 12.4 10.5 28.0 11.9 11.0 16.4 18.9 9.6 22.9 14.5 16.8 17.7 17.1 13.5 17.9 12.3 7.5 6.8 18.5 36.7 16.7 19.8 11.8 6.6 13.2 19.9 14.4 17.9 24.4 10.2 17.8 16.6 10.9 21.1 18.7 11.4 18.9 24.8 21.3 6.9 19.4 15.8 9.0 9.4 18.6 18.5 15.2 19.2 15.0 20.4 4.1 3.2 6.6 3.9 6.6 7.6 2.1 9.5 6.9 10.4 10.7 22.2 14.2 5.7 15.1 20.5 16.0 18.4 9.3 6.6 9.0 14.6 21.6 11.0 12.9 12.4 17.5 18.6 7.0 11.5 4.5 6.7 12.5 10.0 14.8 19.2 11.1 14.8 10.7 13.8 13.0 5.2 15.4 12.4 6.9 10.9 6.5 8.6 8.4 7.7 10.1 14.3 19.2 9.0 8.8 9.9 6.3 16.7 11.4 7.1 16.7 17.5 9.4 6.6 11.1 8.0 10.3 9.6 7.3 5.5 19.4 1.1 3.0 6.4 6.1 3.7 4.9 2.0 4.9 7.6 3.2 4.1 4.1 5.4 6.6 6.6 3.9 2.9 5.7 2.1 6.9 12.4 11.9 11.0 7.5 6.8 11.8 6.6 10.2 9.4 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757747-89791063 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavourable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavourable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favourable (8.05e-4)" 12.0 5.5 9.3 11.2 7.9 13.6 10.0 3.0 9.3 9.7 7.9 10.6 5.2 3.5 10.9 7.8 8.3 7.0 17.3 11.6 9.2 8.6 7.7 10.4 18.7 10.9 11.8 5.8 8.9 13.2 14.7 7.3 20.8 9.1 10.7 5.6 4.6 10.2 5.8 3.1 10.4 6.9 10.4 16.5 14.2 8.3 5.6 11.5 5.1 8.5 4.9 11.8 15.0 7.6 7.5 6.9 19.4 11.2 3.8 5.5 4.3 10.1 3.5 1.8 2.6 4.4 6.1 3.3 11.3 19.3 6.0 7.8 3.1 5.3 7.9 17.6 6.3 2.4 4.8 3.7 11.1 5.6 4.9 6.6 1.7 3.1 12.4 2.4 3.2 4.9 3.0 8.5 27.7 6.3 3.2 2.6 5.5 2.1 0.0 5.0 1.0 8.4 1.7 2.5 3.8 14.0 4.6 0.3 2.0 2.7 7.1 5.3 6.8 3.0 5.6 3.7 3.5 6.2 5.2 5.2 2.3 4.7 9.0 0.2 2.4 8.8 5.7 19.4 3.6 10.6 4.1 7.5 5.5 4.7 6.9 4.3 5.2 5.5 4.5 3.8 11.2 2.3 1.2 4.3 9.3 7.9 3.0 7.4 9.2 8.6 11.8 5.8 9.1 11.5 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336021-24340045 "Enzymes, Predicted intracellular proteins" Necrosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.2;CAPAN-2: 8.1;HDLM-2: 4.6;SK-BR-3: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 7.6 1.3 1.8 9.7 2.4 4.3 6.0 0.9 1.6 4.5 13.6 1.8 1.4 10.6 3.7 3.8 9.2 3.2 12.7 2.6 2.7 0.6 3.8 1.3 6.4 7.2 3.9 0.8 1.7 8.4 0.5 0.9 3.7 2.3 3.7 11.8 3.6 7.5 1.7 2.1 5.9 25.8 2.1 3.8 15.1 9.2 1.6 3.6 7.2 8.7 6.1 13.3 4.6 5.6 3.5 5.2 6.3 8.8 3.9 9.1 4.3 0.0 0.0 0.0 0.0 3.1 3.4 0.0 0.7 4.2 0.0 0.0 0.1 8.1 0.1 2.1 0.3 2.0 0.0 0.1 0.0 4.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.1 13.3 0.0 2.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 2.6 5.1 6.3 6.3 7.7 6.4 3.5 5.4 6.2 5.2 3.5 2.9 4.0 2.6 3.9 8.8 2.6 9.1 4.3 1.8 2.4 0.9 1.6 2.7 0.6 3.9 0.8 2.3 3.6 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767106 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 16.3;HaCaT: 24.0;hTCEpi: 16.2;PC-3: 13.4;RPTEC TERT1: 14.5;RT4: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "naive CD4 T-cell: 1.5;neutrophil: 2.2" "Group enriched" "Detected in many" 17 "granulocytes: 2.2;T-cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030942 Enhanced "HPA030942: " "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (6.22e-5)" "prognostic unfavourable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favourable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.0 0.2 0.2 0.8 0.2 0.1 3.3 0.2 0.2 6.7 9.4 0.3 12.0 6.8 1.7 6.5 42.1 4.2 17.1 1.1 0.4 0.2 10.8 17.3 5.4 0.4 0.2 0.1 1.8 14.4 4.7 6.8 2.8 1.1 10.6 1.3 4.8 10.2 14.8 0.2 11.7 11.6 2.0 0.3 0.2 11.2 2.7 0.0 8.1 13.6 12.3 26.6 5.2 11.0 0.0 0.0 2.2 0.1 0.0 1.5 0.2 7.0 4.5 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.1 11.7 16.3 0.0 6.9 1.4 24.0 0.3 9.7 0.0 0.0 4.8 0.0 3.3 4.3 0.0 0.0 0.0 0.0 16.2 0.1 2.2 0.0 0.0 0.0 0.0 5.1 0.9 0.0 0.4 13.4 0.0 0.0 1.1 14.5 15.5 2.3 0.1 7.8 8.0 7.3 4.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.1 1.1 0.0 RLIM "MGC15161, NY-REN-43, RNF12" ENSG00000131263 "Ring finger protein, LIM domain interacting" Q9NVW2 X 74585217-74614617 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018895 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA018895: AB_1856323" "unprognostic (1.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.31e-3)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (8.98e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.25e-1)" "unprognostic (3.82e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (6.04e-4)" "unprognostic (1.20e-1)" 11.8 14.3 17.5 10.6 25.6 37.4 12.4 12.6 20.5 12.2 7.4 8.3 5.6 6.4 10.6 8.0 10.2 9.5 10.7 10.5 17.1 16.6 11.6 9.7 13.8 9.2 12.4 13.7 12.4 9.7 19.5 18.5 10.5 28.6 11.9 7.6 5.2 8.9 8.7 11.2 10.2 7.1 10.1 13.9 9.8 8.4 6.9 12.4 9.7 13.0 6.2 10.1 10.5 9.3 3.5 4.8 16.3 7.4 5.2 4.6 3.0 13.5 13.8 13.4 11.2 13.5 14.3 13.2 13.1 15.2 11.7 14.5 10.7 14.2 7.3 15.3 16.4 11.8 26.9 15.7 18.0 6.6 14.2 12.8 24.3 6.5 12.0 19.3 22.9 13.8 9.9 16.7 28.7 13.6 11.1 13.3 15.4 10.3 14.3 10.9 20.6 13.3 13.7 28.4 12.3 10.9 16.2 9.9 11.5 24.5 11.9 15.2 6.7 15.2 18.0 14.2 13.8 14.5 11.4 7.1 13.6 11.7 15.5 19.6 13.8 16.3 5.9 5.6 3.2 7.4 3.3 3.0 4.1 4.0 4.8 3.5 4.5 4.1 11.4 5.2 5.4 2.6 4.6 3.0 17.5 25.6 12.6 20.5 17.1 16.6 12.4 13.7 28.6 12.4 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603393-86623866 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved "HPA057922: " "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favourable (6.77e-5)" 13.2 13.5 18.0 9.8 20.6 9.8 18.5 38.3 24.6 15.8 28.1 16.9 9.6 15.6 18.8 39.7 11.7 12.7 23.3 29.5 16.7 15.9 13.1 43.8 8.6 8.5 17.8 10.6 13.2 20.2 23.8 12.2 16.2 14.7 20.5 14.2 14.5 13.8 16.1 17.7 10.4 27.2 17.9 21.8 8.1 18.7 13.7 16.5 11.9 9.0 8.8 8.3 13.4 11.5 1.4 1.6 9.9 0.9 3.0 3.4 0.9 5.6 7.7 3.9 6.0 18.0 11.7 6.4 8.1 12.5 4.2 5.7 4.4 9.7 9.4 9.9 12.2 6.9 5.2 6.4 6.4 7.8 7.1 5.3 3.5 9.8 17.1 1.7 8.0 16.9 13.5 6.2 7.8 12.6 1.9 5.7 11.5 6.9 4.0 4.7 1.8 5.5 2.5 16.9 5.5 15.4 8.9 6.2 6.4 9.6 21.5 8.0 8.2 4.4 14.2 8.2 3.9 8.2 4.8 19.9 6.6 6.3 6.5 3.0 3.9 6.5 0.7 9.9 1.1 0.9 1.5 1.4 1.6 2.4 1.6 1.4 1.9 1.3 1.5 3.0 0.6 1.0 3.4 0.9 18.0 20.6 38.3 24.6 16.7 15.9 17.8 10.6 14.7 16.5 RNF111 "ARK, Arkadia, DKFZP761D081, FLJ38008" ENSG00000157450 "Ring finger protein 111" Q6ZNA4 15 58865175-59097419 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038576, HPA038577" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA038576: AB_10964492, HPA038577: AB_10960052" "unprognostic (7.30e-2)" "unprognostic (2.60e-2)" "unprognostic (2.39e-1)" "unprognostic (3.37e-1)" "unprognostic (7.94e-2)" "unprognostic (2.09e-1)" "unprognostic (2.19e-1)" "unprognostic (3.21e-1)" "unprognostic (5.10e-2)" "unprognostic (6.12e-3)" "unprognostic (3.10e-2)" "unprognostic (1.42e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (9.74e-2)" 12.8 11.2 15.3 15.6 19.3 21.2 12.7 24.1 21.9 15.1 9.8 18.8 10.9 11.4 16.4 9.8 16.2 12.6 13.0 11.0 13.0 13.0 12.9 14.8 13.3 13.9 15.7 15.5 16.8 14.8 20.8 19.2 16.7 17.8 12.7 10.3 12.9 14.9 12.5 15.0 14.1 10.9 11.7 14.2 14.3 12.0 15.7 16.9 14.9 16.4 6.5 17.8 15.8 14.8 7.9 5.2 26.7 9.9 3.3 6.1 2.0 9.7 22.7 14.5 12.4 12.6 14.2 12.4 12.8 15.0 12.8 16.5 9.9 6.5 12.0 14.5 17.8 19.2 3.9 9.5 16.0 12.4 8.1 14.9 9.2 7.6 13.7 8.6 16.8 11.1 10.4 13.8 15.3 14.2 13.7 12.1 15.7 4.7 11.4 5.6 11.9 8.8 11.5 20.7 9.8 9.8 17.5 11.9 17.4 11.5 11.4 11.1 8.9 10.7 16.3 20.5 17.2 10.7 12.2 8.7 11.9 14.3 12.5 14.0 15.4 6.4 9.9 9.3 4.8 7.0 4.8 7.4 4.9 4.3 5.2 7.9 5.5 4.2 26.7 3.3 7.6 4.9 6.1 2.0 15.3 19.3 24.1 21.9 13.0 13.0 15.7 15.5 17.8 16.9 RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 47.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.1;fHDF/TERT166: 4.7;SCLC-21H: 4.7;SH-SY5Y: 8.2;U-87 MG: 26.9" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015970 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" 2.5 8.1 11.3 2.3 15.9 0.6 1.8 47.5 29.1 1.2 3.6 1.4 0.0 2.9 2.0 6.9 1.1 1.5 4.4 2.3 12.4 8.2 1.2 0.7 1.7 1.4 3.9 14.1 1.3 0.8 0.5 1.9 1.1 3.1 10.2 4.4 1.6 1.3 3.5 2.1 1.9 3.6 3.5 2.9 1.7 2.1 2.0 3.7 0.0 0.9 0.0 0.8 2.8 1.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 4.1 0.1 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 4.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.3 0.0 0.0 1.7 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 0.1 0.1 0.0 0.0 4.7 8.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 26.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 15.9 47.5 15.9 12.4 8.2 3.9 14.1 3.1 3.7 RNF114 "PSORS12, ZNF313" ENSG00000124226 "Ring finger protein 114" Q9Y508 20 49936336-49953892 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021184 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA021184: AB_1859185" "unprognostic (8.38e-2)" "unprognostic (3.56e-2)" "unprognostic (5.62e-2)" "prognostic unfavourable (8.10e-6)" "unprognostic (1.56e-1)" "unprognostic (2.96e-1)" "prognostic unfavourable (3.11e-4)" "unprognostic (2.50e-2)" "unprognostic (1.03e-2)" "unprognostic (2.12e-1)" "unprognostic (3.99e-1)" "unprognostic (2.70e-2)" "unprognostic (2.54e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "prognostic favourable (3.01e-4)" "unprognostic (1.36e-2)" 23.2 21.3 24.4 18.3 25.7 31.2 20.6 26.7 23.1 24.0 29.7 32.6 21.1 29.5 20.3 23.4 20.2 23.6 20.1 21.9 23.0 25.3 30.3 31.6 24.4 24.0 28.3 19.4 28.4 36.8 16.1 21.6 40.6 23.7 24.5 21.3 27.1 27.8 24.1 43.8 15.2 33.9 17.6 29.3 36.3 24.2 101.9 24.1 28.3 37.9 20.0 24.1 22.6 25.0 28.5 32.5 43.4 44.6 23.7 29.4 34.9 15.6 15.4 7.9 8.3 16.3 11.3 23.3 14.0 15.9 29.0 12.3 45.7 12.9 7.6 28.0 7.4 12.6 11.8 14.1 10.0 13.7 8.6 9.6 10.3 32.1 14.3 17.4 11.6 9.8 13.0 11.1 7.6 6.9 18.0 8.9 8.5 52.6 14.6 18.1 8.2 22.1 16.0 8.3 13.7 15.3 12.8 12.1 8.7 17.1 108.1 21.6 28.8 16.2 9.1 26.3 12.2 13.8 16.1 18.3 19.1 14.4 14.9 11.4 14.5 38.5 42.5 35.7 22.0 39.2 24.6 28.2 24.6 22.4 32.5 28.5 29.4 23.7 43.4 23.7 44.6 26.7 28.8 34.9 24.4 25.7 26.7 23.1 23.0 25.3 28.3 19.4 23.7 24.1 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824077 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 7.2 5.2 6.8 4.8 6.8 6.4 7.7 16.2 7.0 6.3 3.4 4.6 5.7 3.5 8.9 5.0 5.8 4.3 4.8 23.5 5.8 5.6 5.1 3.9 5.6 4.7 6.2 4.7 4.5 5.8 5.9 3.5 5.2 6.5 3.8 7.3 3.6 5.6 27.6 3.8 3.1 10.9 4.5 4.2 3.8 3.4 4.5 6.0 5.0 5.4 4.5 4.1 6.3 2.7 2.4 9.0 2.2 3.2 3.2 1.4 11.1 4.6 5.7 4.2 10.4 13.7 4.6 8.4 15.7 6.2 7.6 5.0 4.1 7.8 9.6 12.0 7.8 6.3 5.8 6.8 7.8 4.1 6.2 5.9 4.6 6.6 9.7 14.5 7.9 5.1 6.3 7.6 8.0 6.1 12.8 11.3 8.4 7.1 6.2 7.2 9.8 6.8 5.7 6.5 12.2 3.8 5.7 7.9 6.8 8.5 6.2 9.3 9.3 9.8 9.1 7.1 5.4 8.9 10.8 10.2 8.3 4.6 6.6 5.7 9.0 2.2 3.2 3.2 1.5 2.7 2.7 2.2 3.2 1.8 2.4 2.3 3.1 1.7 3.2 1.6 2.4 2.0 1.4 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689499-49721529 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Approved Approved Cytosol Cytosol "HPA065983: , HPA071879: " "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favourable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 5.3 8.0 7.7 8.0 10.4 17.5 5.0 13.8 13.6 5.2 6.8 6.2 7.8 12.7 6.4 8.0 7.5 6.4 7.0 12.9 8.5 6.8 8.4 21.8 5.7 6.1 7.3 6.6 5.1 7.7 8.9 8.4 7.3 6.6 7.3 4.8 7.6 6.9 6.7 81.2 7.7 12.5 6.2 6.7 7.6 6.9 8.8 7.8 8.3 6.2 12.0 9.1 6.6 4.8 11.3 12.7 11.8 10.9 7.7 11.4 5.3 6.7 9.5 11.4 11.7 17.3 10.7 12.3 8.8 11.7 11.2 12.5 10.1 11.7 16.4 8.0 12.5 8.5 8.6 13.3 7.9 10.9 11.7 13.4 18.8 22.2 17.3 12.9 14.5 13.5 13.1 10.5 12.3 11.6 14.0 14.3 9.5 10.1 13.6 21.0 6.2 15.4 6.4 6.9 17.0 15.4 11.4 7.8 15.6 12.1 10.8 13.4 11.1 23.3 11.9 9.9 12.1 8.9 10.8 19.4 19.0 6.6 14.0 16.4 14.8 11.8 10.9 7.9 11.4 9.5 6.8 9.8 7.2 6.8 8.6 11.3 8.7 8.2 6.3 7.7 9.7 12.7 5.5 5.3 7.7 10.4 13.8 13.6 8.5 6.8 7.3 6.6 6.6 7.8 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018372-32073213 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "HMC-1: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavourable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 21.9 2.3 4.1 9.1 5.7 18.2 20.4 1.2 6.6 5.0 8.9 12.2 3.3 12.3 7.2 5.5 3.9 4.3 6.0 5.4 6.1 4.1 2.1 14.1 10.3 13.5 7.7 3.1 2.4 4.2 2.5 1.3 4.4 7.0 3.1 7.8 1.6 5.0 1.9 4.4 6.0 26.0 4.1 12.0 7.4 4.2 3.3 8.3 14.8 3.2 2.9 7.2 4.5 6.2 2.1 3.4 9.0 3.8 11.7 12.5 5.1 0.7 0.1 0.1 0.2 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 0.5 0.9 0.7 0.1 3.9 1.6 0.2 0.2 0.2 0.1 5.1 31.8 1.0 1.5 0.0 1.7 0.3 0.1 1.1 0.0 1.1 1.3 4.8 2.6 0.9 5.4 0.3 0.1 0.3 0.3 0.5 0.2 0.1 0.1 7.8 0.8 2.5 0.1 0.1 0.5 0.1 0.0 3.7 0.1 0.1 0.4 6.8 4.2 9.0 3.8 3.3 12.5 2.0 8.2 2.0 10.1 10.5 3.4 2.1 8.2 10.6 1.5 11.7 1.9 3.4 10.0 5.1 4.1 5.7 1.2 6.6 6.1 4.1 7.7 3.1 7.0 8.3 RNF126 FLJ20552 ENSG00000070423 "Ring finger protein 126" Q9BV68 19 647526-663277 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043050 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA043050: AB_10794768" "unprognostic (2.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-1)" "unprognostic (2.48e-3)" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (9.96e-3)" "unprognostic (7.04e-3)" "unprognostic (3.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 14.2 14.2 13.4 17.0 13.7 18.7 14.5 12.2 24.7 9.8 16.0 14.8 7.4 24.3 10.4 9.2 19.8 9.5 13.1 14.2 13.1 10.2 11.6 27.9 10.4 19.9 11.4 11.6 12.1 22.4 5.9 10.0 14.1 12.3 10.0 6.3 10.1 13.2 9.3 50.3 21.9 20.3 9.9 10.0 18.6 21.0 33.6 9.3 16.1 8.6 19.5 18.6 13.1 11.2 15.9 13.6 7.5 13.8 17.1 17.3 9.2 25.9 8.6 7.3 10.4 1.7 2.4 12.5 13.7 5.2 7.9 7.5 17.4 9.1 21.5 8.9 5.7 17.5 4.4 10.2 2.2 14.2 31.8 10.9 9.0 14.4 6.6 21.7 16.1 4.1 8.1 6.5 5.1 7.2 21.9 21.7 4.1 20.9 22.1 10.2 19.5 17.0 16.1 6.3 33.9 6.0 14.5 17.5 13.6 10.3 13.6 14.0 8.7 17.1 9.4 14.4 10.4 21.1 23.3 38.4 19.0 25.2 18.3 12.7 14.8 0.6 9.8 7.5 17.3 11.5 14.2 15.9 15.7 16.7 12.4 15.6 12.2 11.4 2.2 17.1 13.8 13.6 16.8 9.2 13.4 13.7 12.2 24.7 13.1 10.2 11.4 11.6 12.3 9.3 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128, E3 ubiquitin protein ligase" Q8TEB7 X 106693794-106796993 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.6;liver: 48.4;thyroid gland: 38.4" "Cell line enhanced" "Detected in some" "BEWO: 17.9;CAPAN-2: 14.8;Hep G2: 12.6;RPTEC TERT1: 13.0;RT4: 37.2;WM-115: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain "HPA019675: " "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 1.4 20.6 2.4 2.2 7.2 0.0 3.0 0.7 4.2 0.5 24.4 0.9 0.4 24.2 0.2 2.2 4.0 0.3 27.2 0.6 2.8 5.1 24.4 48.4 6.7 0.0 2.4 2.1 0.7 14.5 0.0 11.0 10.5 4.0 3.4 7.8 0.0 25.4 0.8 3.0 3.6 54.6 0.9 1.1 0.2 17.9 0.3 1.0 1.1 38.4 2.3 2.7 10.2 3.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 4.5 0.0 0.0 0.0 1.5 0.8 17.9 0.0 0.1 0.0 0.0 7.8 14.8 0.0 0.0 0.2 5.6 0.0 0.0 0.0 0.0 8.7 0.0 0.1 12.6 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 13.0 37.2 0.0 0.0 0.0 0.9 0.9 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 7.2 0.7 4.2 2.8 5.1 2.4 2.1 4.0 1.0 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812708-149962139 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 72.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles" Cytosol "HPA064784: " "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favourable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 24.0 21.3 30.6 19.0 39.4 9.8 28.5 19.9 30.4 19.0 17.7 39.9 16.2 14.3 16.8 33.7 16.8 15.9 20.4 16.4 40.5 29.7 35.8 39.2 31.7 19.6 60.9 26.8 18.1 19.6 23.5 14.9 32.4 40.7 25.5 20.3 19.5 36.1 20.9 18.0 18.4 16.3 20.4 102.2 25.5 17.0 12.5 51.2 13.3 32.1 18.8 15.9 21.4 16.5 8.8 15.7 72.4 31.5 7.8 8.5 14.6 19.4 12.1 8.2 9.3 32.3 19.8 13.7 10.8 27.8 10.4 15.5 10.6 28.0 8.1 15.8 13.2 18.5 11.0 13.8 14.7 9.9 8.0 9.7 5.6 10.3 21.5 10.4 13.9 20.9 26.3 8.8 23.9 11.5 3.0 16.5 9.3 10.9 7.5 6.9 5.5 9.5 5.4 8.8 34.3 20.2 9.1 4.3 12.5 8.9 13.4 34.7 25.5 11.1 12.0 14.2 5.7 15.0 6.9 28.0 18.4 16.7 11.9 9.8 7.6 12.9 20.3 16.6 6.8 25.2 8.5 8.8 7.6 7.6 15.7 8.3 7.3 7.5 72.4 7.8 31.5 11.2 8.3 14.6 30.6 39.4 19.9 29.2 40.5 29.7 60.9 26.8 40.7 51.2 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072118 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 17.0;classical monocyte: 38.1;eosinophil: 24.6;intermediate monocyte: 27.5;myeloid DC: 31.1;neutrophil: 68.1;non-classical monocyte: 23.8;plasmacytoid DC: 22.9" "Group enriched" "Detected in all" 11 "dendritic cells: 31.1;granulocytes: 68.1;monocytes: 38.1" "Low region specificity" "Detected in all" HPA014499 Approved "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favourable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 36.3 16.3 23.5 16.3 32.5 29.5 24.0 19.0 25.3 26.0 16.7 56.0 19.0 10.6 18.5 12.0 10.6 19.5 21.9 17.0 27.8 21.1 20.7 64.4 25.5 19.1 50.2 20.3 21.7 28.6 11.0 16.7 19.8 30.3 16.3 16.1 15.8 30.6 28.3 17.3 7.9 12.1 22.2 58.2 20.4 20.5 7.3 38.8 2.5 14.3 6.3 10.3 20.7 13.3 1.2 31.1 68.1 38.1 4.0 2.0 20.3 7.9 5.8 28.6 20.9 27.9 15.2 5.4 6.2 7.8 6.8 7.4 1.8 6.8 0.0 19.2 10.8 0.8 19.9 12.6 7.5 0.1 17.7 15.6 3.2 4.0 7.1 3.8 41.0 14.3 6.7 0.5 3.9 11.1 3.2 0.1 6.8 12.0 7.1 12.1 7.8 8.9 16.0 6.6 0.0 8.6 1.4 17.4 7.8 11.6 6.3 24.0 9.1 9.0 8.6 11.6 4.6 8.1 6.6 0.0 6.1 1.6 1.4 30.1 9.0 17.0 38.1 24.6 2.0 27.5 1.9 1.2 0.9 1.0 31.1 1.2 1.0 1.2 68.1 4.0 23.8 22.9 0.1 20.3 23.5 32.5 19.0 25.3 27.8 21.1 50.2 20.3 30.3 38.8 RNF133 ENSG00000188050 "Ring finger protein 133" Q8WVZ7 7 122697712-122699156 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 28.3" "Cell line enhanced" "Detected in some" "Karpas-707: 4.0;MCF7: 1.5;NTERA-2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.82e-1)" "unprognostic (2.52e-2)" "unprognostic (1.77e-1)" "unprognostic (3.04e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.87e-3)" "unprognostic (3.56e-2)" "unprognostic (3.72e-1)" "unprognostic (3.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.02e-2)" "unprognostic (7.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.39e-1)" "unprognostic (2.37e-2)" "unprognostic (7.61e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.2 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 4.0 0.0 1.5 0.0 0.0 1.2 1.1 0.0 0.0 0.8 0.0 0.4 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.1 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30968785-30999911 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles Vesicles "HPA021576: AB_1856331, HPA052404: " "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavourable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 18.2 11.6 6.5 15.9 7.1 7.1 28.8 6.4 6.1 16.3 22.2 7.2 16.5 9.7 15.7 16.8 18.4 11.8 14.4 7.4 7.1 4.8 19.5 6.0 19.0 28.0 6.8 2.5 15.1 11.7 15.0 5.9 19.2 6.3 18.1 13.2 13.6 13.3 14.8 7.5 21.4 16.7 13.9 6.1 22.7 10.0 8.8 4.8 6.0 25.0 12.7 18.8 13.0 19.1 11.8 18.4 21.7 25.1 5.4 5.3 9.7 5.8 12.2 0.7 12.1 16.7 13.3 10.3 4.7 7.0 4.6 4.0 0.0 4.4 4.7 6.9 8.9 7.5 6.0 5.7 3.6 4.5 2.6 2.2 3.6 0.0 11.7 5.9 5.1 13.2 30.2 4.8 15.6 7.2 0.0 16.2 7.3 7.8 0.0 6.0 4.9 6.6 12.4 0.0 17.3 6.3 8.4 4.5 0.2 6.7 2.8 6.7 18.5 9.2 6.3 0.0 1.6 7.4 5.3 0.2 0.5 3.4 8.1 10.2 6.2 9.1 24.0 12.1 5.3 21.8 2.9 11.8 2.8 2.7 18.4 11.2 1.5 2.7 21.7 5.4 25.1 6.6 3.8 9.7 6.5 7.1 6.4 6.1 7.1 4.8 6.8 2.5 6.3 4.8 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091855-32131561 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 43.8;bone marrow: 40.4;lymphoid tissue: 28.3;testis: 73.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 8.2 5.0 6.5 11.0 7.4 40.4 7.7 9.9 7.1 6.5 11.0 9.0 5.8 8.0 7.5 6.3 7.4 9.7 7.1 5.0 6.8 6.4 5.9 10.1 7.6 17.9 10.6 6.3 9.0 7.8 5.6 8.7 7.2 6.7 6.5 10.0 4.5 6.9 4.9 5.1 5.6 11.2 5.6 9.1 14.3 6.6 73.4 8.1 28.3 7.0 5.7 9.9 6.1 6.8 14.4 24.3 25.7 24.9 16.4 43.8 24.2 8.9 5.3 22.0 10.9 2.8 6.0 12.5 9.2 5.2 11.5 13.4 6.2 6.3 21.6 11.5 6.0 9.4 11.5 10.4 15.7 12.0 19.2 17.0 6.9 7.6 11.3 46.8 15.1 5.8 10.4 12.7 18.1 11.7 23.4 8.9 7.4 8.5 31.6 21.0 24.6 7.4 32.7 13.8 12.4 10.5 6.7 25.0 12.5 12.3 7.1 9.5 4.6 19.8 9.0 13.9 10.2 3.4 10.2 14.8 19.5 37.5 7.6 26.2 13.6 8.0 24.9 24.0 10.5 18.6 13.4 14.0 22.9 14.8 24.3 14.4 43.8 27.9 25.7 16.4 15.3 10.5 16.7 24.2 6.5 7.4 9.9 7.1 6.8 6.4 10.6 6.3 6.7 8.1 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474738-124487914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 15.1 17.3 10.4 9.5 12.2 54.5 13.4 12.0 17.1 14.2 10.9 14.0 9.4 6.2 15.3 10.0 12.2 14.2 11.0 11.4 10.4 10.8 11.4 17.7 11.3 14.2 12.4 11.5 17.1 10.3 7.6 10.6 18.4 9.9 12.8 10.4 10.2 10.3 10.5 15.2 12.6 11.3 14.2 12.2 11.8 11.2 60.3 13.3 16.8 11.2 9.6 10.4 14.8 10.7 9.2 9.4 11.8 11.7 8.6 13.9 8.0 13.2 8.9 10.7 10.5 23.6 18.8 8.8 11.9 22.6 10.0 12.9 5.7 11.1 13.7 14.0 15.4 9.8 9.1 14.5 15.0 18.9 11.4 20.3 5.8 11.7 18.0 9.6 11.8 16.0 21.2 10.6 28.7 13.3 14.3 21.0 11.8 35.8 16.2 6.9 7.5 12.6 6.5 7.9 13.7 18.8 17.0 4.5 11.7 15.5 38.9 16.8 18.7 10.4 10.5 6.7 15.5 11.3 13.2 17.1 18.1 12.4 10.5 16.3 6.7 3.3 7.4 11.8 11.6 4.7 13.9 9.2 10.8 13.2 9.4 8.5 10.8 11.3 10.8 8.6 11.7 5.1 13.2 8.0 10.4 12.2 12.0 17.1 10.4 10.8 12.4 11.5 9.9 13.3 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990291 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008716 Approved Supported Cytosol Cytosol "HPA008716: AB_1856337" "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favourable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavourable (2.21e-4)" "unprognostic (1.06e-2)" 21.2 29.5 23.7 11.2 33.9 7.8 22.0 22.5 40.2 18.4 18.7 26.2 16.0 15.3 21.0 21.5 15.6 14.3 15.4 32.9 23.6 24.7 31.3 31.3 13.8 13.3 28.9 17.3 15.9 17.1 26.3 28.8 23.6 47.7 21.6 19.8 20.9 18.1 20.1 27.7 11.9 20.9 20.5 26.3 13.8 15.7 33.7 15.0 16.2 26.3 13.3 14.9 16.7 14.0 12.3 17.1 32.6 18.8 16.8 17.0 12.2 12.5 21.0 14.8 29.0 26.6 27.9 9.9 25.8 14.4 18.2 20.2 17.4 14.7 22.2 30.3 26.5 6.9 18.8 25.4 16.3 16.7 16.2 14.1 11.0 7.9 29.3 15.5 12.6 20.9 22.4 24.1 30.4 22.5 17.1 31.1 37.2 15.0 15.0 4.9 6.2 24.0 9.9 16.4 24.1 25.0 21.8 16.3 13.3 22.6 41.5 43.9 28.9 12.1 23.2 24.2 7.8 11.4 24.4 19.6 22.8 20.4 20.7 19.0 29.8 32.6 13.4 13.0 17.0 15.8 16.5 12.3 15.0 16.9 16.2 10.6 11.5 16.7 3.3 16.8 18.8 17.1 16.7 12.2 23.7 33.9 22.5 40.2 23.6 24.7 28.9 17.3 47.7 15.0 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917392-7068286 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell line enhanced" "Detected in many" "HMC-1: 50.4;SH-SY5Y: 15.3;SK-MEL-30: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Approved Vesicles Vesicles "HPA049939: " "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavourable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favourable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 12.9 28.8 13.3 4.2 21.2 12.1 11.1 45.5 20.7 17.3 5.2 28.7 9.0 3.0 26.0 8.3 4.7 8.4 7.5 8.0 15.6 11.6 7.5 1.8 5.7 7.9 26.5 12.2 20.0 29.7 21.5 12.5 6.2 13.2 8.7 5.7 5.9 4.0 7.4 8.7 5.7 4.1 12.2 21.8 21.1 2.8 5.0 27.1 3.4 3.2 1.2 5.8 5.8 6.5 0.1 0.2 8.7 0.1 0.8 4.1 0.6 0.3 2.2 11.7 2.4 2.6 5.5 9.0 0.0 0.0 0.4 1.1 0.0 0.2 1.1 1.3 0.1 0.2 3.8 0.0 0.0 0.6 1.0 14.9 0.1 4.4 0.1 0.2 50.4 8.7 0.0 0.8 0.0 0.0 6.4 0.2 0.0 1.8 7.6 0.6 4.3 5.3 5.9 8.5 0.9 0.3 3.9 3.9 15.3 0.2 1.5 15.1 0.6 0.9 0.0 1.5 4.0 4.1 1.7 4.1 1.3 0.0 5.8 3.3 5.5 1.5 0.1 8.7 2.1 0.0 3.0 0.1 2.1 1.5 0.2 0.1 4.1 2.8 0.4 0.8 0.0 0.0 0.8 0.6 13.3 21.2 45.5 20.3 15.6 11.6 26.5 12.2 13.2 27.1 RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468874 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 54.7;hTCEpi: 17.4;HUVEC TERT2: 16.1;TIME: 16.1;U-698: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 28.8" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;granulocytes: 15.6;monocytes: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: , HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" 16.3 2.0 4.6 11.1 6.8 15.7 21.1 5.1 7.5 8.0 4.2 2.8 4.6 1.5 6.8 7.5 9.4 9.0 6.8 8.7 5.3 4.3 13.8 11.4 39.0 11.1 8.3 2.3 4.2 3.7 3.0 2.3 11.1 8.8 12.8 2.3 8.3 16.9 6.2 36.8 19.2 3.7 4.9 9.2 37.1 4.3 3.3 6.9 5.8 32.9 11.4 12.2 7.3 6.6 2.0 7.9 15.6 28.8 0.2 0.7 2.6 1.3 0.2 0.1 0.0 0.0 0.6 2.9 1.5 1.6 3.2 3.5 0.0 0.1 54.7 15.0 0.6 4.7 0.0 4.6 4.6 0.2 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.8 17.4 1.2 3.9 16.1 0.0 0.0 0.8 0.5 0.4 0.0 0.4 0.3 0.2 0.5 3.3 9.8 3.0 0.5 0.0 0.3 7.0 5.2 8.2 0.1 16.1 2.5 0.5 0.2 0.3 0.0 0.0 46.0 0.3 0.1 0.2 0.1 9.1 5.1 0.2 16.4 0.7 2.0 0.3 0.3 5.6 1.6 0.7 0.4 15.6 0.2 28.8 7.9 0.2 2.6 4.6 6.8 5.1 7.5 5.3 4.3 8.3 2.3 8.8 6.9 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavourable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 13.3 20.1 23.9 15.6 23.0 7.1 24.1 30.2 27.3 11.3 11.7 5.7 5.3 4.7 12.6 13.6 26.7 11.4 20.8 16.8 22.0 8.4 8.2 6.1 30.7 36.3 17.5 9.7 14.1 6.0 26.9 29.0 21.9 18.5 11.8 12.6 10.2 17.8 14.8 5.5 14.9 11.0 13.8 12.4 12.7 11.2 7.9 18.0 12.4 14.3 8.0 19.6 19.3 15.7 8.9 2.7 14.4 2.6 2.1 6.2 1.3 20.1 20.0 30.7 36.8 32.5 14.5 6.0 16.2 28.3 15.0 24.4 6.9 16.8 6.9 29.1 14.2 26.5 24.2 21.3 26.5 28.5 8.6 14.6 22.7 5.7 13.9 9.6 14.0 8.9 38.5 13.9 20.5 14.7 14.5 26.8 14.0 0.5 10.9 3.0 13.2 10.2 14.6 13.4 13.8 20.0 7.0 11.2 20.7 16.3 17.5 26.6 12.3 8.8 15.6 16.8 15.5 13.4 28.6 5.9 8.3 6.5 19.6 12.0 36.0 2.8 2.6 14.4 3.2 2.5 3.7 8.9 4.7 3.8 1.9 4.4 6.2 4.3 9.7 2.1 2.2 2.7 5.7 1.3 23.9 23.0 30.2 27.3 22.0 8.4 17.5 9.7 18.5 18.0 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266610-127288567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favourable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favourable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 27.3 20.9 28.5 16.6 29.1 5.1 23.9 63.7 34.5 22.7 18.6 29.2 10.5 11.8 32.0 35.2 14.2 17.9 21.3 25.2 26.3 21.7 20.9 16.8 21.0 17.3 30.0 27.7 28.5 12.6 26.5 27.4 27.8 31.3 18.6 17.6 17.5 16.7 20.3 55.9 16.0 15.2 26.1 28.7 24.6 15.5 16.3 27.7 9.2 26.7 15.5 17.6 19.2 18.7 11.7 14.2 22.8 22.8 11.5 10.3 9.1 5.5 7.0 26.7 23.5 24.7 24.8 9.7 18.9 30.2 10.1 14.5 9.1 8.4 10.0 13.4 15.4 7.1 7.9 8.8 14.8 11.5 6.9 12.7 8.4 12.7 24.5 7.5 9.0 21.6 18.7 11.4 22.8 17.7 13.6 9.8 22.2 10.6 7.3 13.6 9.7 7.3 9.4 6.9 5.0 14.4 6.1 16.0 16.1 7.3 10.4 11.6 7.1 26.0 20.8 17.8 5.9 18.4 13.3 14.2 8.8 6.6 13.6 13.2 16.8 16.8 18.9 16.1 9.3 20.0 9.7 11.1 8.0 10.3 14.2 11.7 7.3 10.2 22.8 11.5 22.8 7.1 8.6 9.1 28.5 29.1 63.7 34.5 26.3 21.7 30.0 27.7 31.3 27.7 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 123.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 123.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 123.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favourable (2.91e-4)" 20.3 13.4 7.9 29.0 10.9 32.9 13.5 7.9 10.8 12.5 16.6 10.8 11.4 12.3 11.3 12.8 28.9 14.3 14.5 12.1 9.5 9.4 15.1 19.6 24.5 47.4 13.7 6.2 14.3 21.1 14.3 10.6 19.4 11.2 11.1 12.0 12.8 15.8 8.1 8.8 20.2 16.8 9.6 13.9 65.0 13.8 15.2 9.7 17.0 12.7 13.1 24.4 14.9 17.2 2.1 9.3 123.7 21.3 2.3 9.0 9.9 9.6 5.7 4.3 5.5 16.3 16.4 25.5 12.0 15.8 16.2 18.3 14.4 25.6 2.8 14.5 11.8 19.7 6.1 12.2 15.1 8.4 8.4 6.0 5.1 24.3 21.8 6.4 9.7 15.0 20.1 19.2 12.7 29.5 5.2 9.0 16.2 8.2 8.6 6.5 3.0 10.4 5.6 7.2 11.1 19.1 23.7 5.7 4.2 7.2 17.9 17.3 4.8 8.7 19.5 8.2 4.7 12.2 2.6 18.3 10.7 0.1 2.6 9.0 6.0 5.8 13.0 14.8 8.2 20.4 7.4 2.1 7.3 8.1 4.8 1.5 5.1 5.3 123.7 2.3 21.3 9.3 9.0 9.9 7.9 10.9 7.9 10.8 9.5 9.4 13.7 6.2 11.2 9.7 RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808063-61894247 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 53.7" "Cell line enhanced" "Detected in many" "HaCaT: 16.0;SH-SY5Y: 9.9;TIME: 9.9;U-138 MG: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favourable (1.13e-8)" "prognostic unfavourable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" 8.3 3.9 2.4 2.3 6.8 1.5 8.8 19.1 3.8 8.5 7.4 4.0 6.2 2.2 8.6 10.4 4.5 3.9 8.0 6.5 2.5 3.1 53.7 28.3 7.8 1.2 4.1 1.4 3.8 3.1 4.7 2.6 6.6 7.7 4.7 6.7 3.4 11.8 6.8 4.6 9.6 9.8 4.6 4.2 1.3 5.7 3.9 4.5 0.0 5.1 4.9 2.0 5.0 11.6 0.5 0.4 1.7 0.4 0.6 0.4 0.2 0.0 0.0 3.5 0.8 3.3 0.4 0.0 2.2 7.0 0.5 0.4 0.0 0.1 0.1 0.7 3.5 16.0 4.3 8.5 0.9 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 0.5 5.9 2.7 1.7 6.4 0.0 0.0 1.0 0.6 0.6 0.0 0.2 0.0 0.2 2.3 0.0 0.3 2.6 2.9 9.9 0.0 6.3 1.1 3.8 0.0 9.9 16.2 1.7 0.0 0.3 0.0 0.0 0.0 0.5 0.0 5.3 1.7 0.3 0.4 0.2 0.3 0.3 0.3 0.3 0.3 0.2 0.5 0.4 0.4 1.5 0.6 0.4 0.4 0.3 0.2 2.4 6.8 19.1 3.8 2.5 3.1 4.1 1.4 7.7 4.5 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142453-76240373 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;skeletal muscle: 52.2;testis: 24.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.3;U-266/70: 21.9;U-266/84: 17.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.5;T-cells: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 10.5 3.5 21.0 3.4 19.4 2.3 2.5 10.7 36.5 1.5 7.6 8.0 0.4 8.2 1.9 3.6 1.5 2.4 1.8 3.6 26.4 15.5 5.1 1.4 1.4 4.5 19.7 12.0 1.4 3.6 8.8 2.7 2.1 25.3 1.8 6.6 6.8 1.9 2.0 52.2 1.5 7.3 2.2 11.3 3.0 2.4 24.7 5.9 0.0 3.8 1.5 2.8 1.5 0.5 0.7 0.4 2.5 0.3 1.1 8.5 1.4 0.1 3.4 12.4 4.5 4.0 2.0 5.7 0.1 3.9 0.8 0.4 1.4 1.3 0.0 1.8 0.3 0.1 10.9 0.0 0.7 41.3 3.7 0.0 1.2 1.9 0.6 0.5 4.7 1.1 0.0 1.5 0.0 0.1 6.4 0.1 1.5 3.3 1.8 0.3 2.0 8.8 0.0 0.1 0.0 1.5 1.3 2.2 10.2 2.2 0.0 4.9 0.3 2.1 0.0 0.8 1.0 6.1 3.9 21.9 17.6 0.0 0.3 0.0 6.3 2.5 0.3 0.4 2.3 0.2 4.9 0.3 5.1 4.0 0.2 0.7 8.5 5.5 1.7 1.1 0.3 0.4 2.1 1.4 21.0 19.4 10.7 36.5 26.4 15.5 19.7 12.0 25.3 5.9 RNF165 "ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6" "Cell line enhanced" "Detected in some" "AF22: 12.5;HaCaT: 6.8;HeLa: 6.7;RPMI-8226: 6.5;SCLC-21H: 12.9;SH-SY5Y: 14.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "MAIT T-cell: 1.1;NK-cell: 3.9;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;NK-cells: 3.9;T-cells: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA041615: , HPA047798: " "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 1.9 1.7 9.9 1.0 9.5 0.9 2.1 28.6 13.8 1.0 0.8 1.7 1.7 0.4 1.0 8.4 2.7 3.0 1.0 2.5 6.1 4.4 2.3 8.3 1.0 0.9 2.2 7.2 0.5 1.0 13.1 4.8 0.8 2.0 3.6 0.6 2.7 1.4 3.9 3.6 3.5 1.0 0.7 1.7 5.3 0.7 1.3 1.0 1.7 8.8 1.2 1.3 1.2 1.0 0.0 1.5 0.5 0.0 3.9 1.1 0.0 1.5 0.1 12.5 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 6.8 0.5 1.0 0.0 0.0 1.0 0.1 6.7 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 1.0 1.7 1.2 2.4 0.5 6.5 0.8 2.1 12.9 14.7 2.3 0.0 0.0 0.3 0.5 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.9 0.0 1.5 0.0 0.0 9.9 9.5 28.6 13.8 6.1 4.4 2.2 7.2 2.0 1.0 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved "HPA049810: " "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favourable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favourable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 30.5 45.9 45.8 32.1 47.0 40.7 38.3 37.9 67.9 44.3 43.5 54.6 49.2 42.7 43.1 55.8 51.6 44.0 47.4 40.1 43.1 39.9 44.1 84.1 35.6 38.7 43.7 43.6 42.6 52.4 52.8 40.7 49.0 41.2 43.6 46.7 38.5 49.1 51.7 56.5 51.6 51.1 42.4 46.4 47.1 42.7 42.0 33.1 53.9 55.1 47.3 47.6 48.1 40.7 25.6 18.2 54.4 26.7 27.6 53.0 37.9 23.7 34.5 15.0 18.4 37.0 18.5 22.4 14.7 20.5 31.1 24.6 24.0 10.9 17.6 28.6 24.2 36.5 26.1 28.5 23.2 16.9 41.9 30.0 43.5 23.6 28.0 14.1 63.2 21.7 45.1 32.3 30.8 20.0 11.7 60.0 24.8 17.0 22.3 17.6 17.9 22.2 15.3 14.9 21.8 35.8 19.9 11.8 14.7 13.5 23.2 19.5 22.2 14.4 12.2 18.6 12.3 16.6 27.9 19.9 20.2 5.8 25.6 20.3 19.4 22.4 21.4 54.4 53.0 22.6 41.1 25.6 40.6 52.7 18.2 24.0 28.5 42.3 52.1 27.6 26.7 18.0 37.7 37.9 45.8 47.0 37.9 67.9 43.1 39.9 43.7 43.6 41.2 33.1 RNF168 FLJ35794 ENSG00000163961 "Ring finger protein 168" Q8IYW5 3 196468783-196503768 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046109 Enhanced "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA046109: " "unprognostic (6.15e-3)" "prognostic favourable (8.21e-4)" "unprognostic (3.11e-1)" "unprognostic (1.11e-2)" "unprognostic (4.22e-1)" "unprognostic (5.04e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (6.81e-3)" "unprognostic (5.30e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (8.31e-4)" "unprognostic (4.83e-3)" "unprognostic (2.80e-3)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.95e-2)" "unprognostic (6.65e-2)" 20.8 9.3 8.9 10.7 11.1 31.6 18.7 21.1 13.0 13.6 11.2 10.7 12.3 11.1 13.9 8.5 14.3 10.1 10.9 12.0 10.2 10.2 7.5 18.8 14.3 12.0 13.8 11.0 14.6 9.2 12.0 8.1 9.9 15.3 10.1 10.8 9.1 11.0 13.6 20.8 20.1 10.1 12.9 10.5 11.7 10.7 18.4 13.4 17.6 9.6 13.9 15.2 14.7 17.1 6.2 5.8 21.8 10.0 7.7 11.6 5.7 12.3 4.9 8.9 11.6 8.3 6.1 12.7 7.6 4.8 5.1 8.1 9.6 6.1 13.1 17.6 6.3 12.6 12.4 9.0 7.9 6.2 6.1 24.9 12.5 11.9 4.3 7.6 6.2 6.0 3.5 8.0 7.1 7.4 7.4 13.8 5.1 20.9 25.1 4.5 10.5 6.5 11.3 10.3 10.6 4.3 17.1 7.4 7.5 8.6 10.6 6.5 16.0 6.8 7.3 8.9 7.0 9.4 10.0 11.8 11.1 19.9 8.7 9.2 7.0 21.8 6.6 7.5 11.6 7.1 10.4 5.7 9.8 8.3 5.8 6.2 8.7 9.1 7.3 7.7 10.0 5.5 6.2 5.7 8.9 11.1 21.1 13.0 10.2 10.2 13.8 11.0 15.3 13.4 RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748868-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA058368" Uncertain Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Nuclear bodies" Cytosol "HPA038505: , HPA046138: , HPA058368: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (3.86e-2)" "unprognostic (3.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "prognostic unfavourable (8.04e-4)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (2.34e-1)" "unprognostic (9.55e-3)" "unprognostic (1.21e-1)" 12.3 7.0 12.0 11.6 14.0 23.1 12.0 22.6 15.6 13.1 11.2 12.2 6.3 7.4 14.2 8.2 20.6 10.7 10.8 9.2 12.6 5.9 8.9 9.3 16.9 11.3 15.4 9.1 14.6 10.7 17.5 10.4 8.6 13.9 10.5 10.0 8.4 12.4 8.8 15.0 14.1 10.3 14.2 10.1 12.6 10.3 7.2 14.9 12.6 11.5 7.4 12.5 13.1 15.8 0.6 0.8 5.0 1.9 1.2 1.6 0.6 8.1 6.3 7.6 7.5 5.0 6.6 3.1 6.4 6.1 7.2 6.3 10.5 6.2 14.6 6.6 7.7 7.9 10.3 7.7 9.5 7.3 6.6 10.1 11.6 4.1 5.7 5.3 8.5 6.1 6.1 8.2 18.7 11.6 8.9 11.8 7.2 6.9 9.1 9.6 3.0 4.1 8.6 18.2 8.0 4.6 8.6 3.4 6.2 8.7 6.6 13.9 8.2 6.9 7.7 12.0 10.1 7.5 5.7 8.6 4.5 17.4 2.4 5.9 6.9 2.8 1.9 1.5 1.6 1.1 1.2 0.3 1.5 0.9 0.8 0.6 1.1 0.9 5.0 1.2 1.0 0.8 1.2 0.6 12.0 14.0 22.6 15.6 12.6 5.9 15.4 9.1 13.9 14.9 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain "HPA050931: , HPA054621: " "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 8.9 13.6 14.3 8.7 17.0 2.2 13.0 15.3 18.8 8.6 10.9 17.5 15.0 10.2 9.8 15.6 14.5 9.7 9.5 8.1 13.7 14.3 17.0 19.4 9.3 8.4 15.7 18.2 13.4 10.8 15.5 16.6 19.0 19.7 11.5 11.7 12.5 12.0 11.5 10.5 14.9 11.3 7.9 21.8 8.8 10.6 7.8 14.2 5.5 29.4 8.0 9.6 10.4 10.6 8.5 11.1 2.6 7.2 5.6 8.0 5.9 6.8 11.2 11.5 5.8 18.8 19.4 6.9 8.3 11.5 7.8 8.5 5.3 22.5 8.4 10.1 7.8 5.9 6.1 8.3 6.7 5.7 6.5 9.7 5.0 5.6 10.5 1.2 7.0 16.8 12.9 5.9 12.4 8.4 8.7 10.0 12.5 2.0 10.2 5.7 5.4 4.0 5.4 15.3 4.7 12.6 6.7 3.0 9.0 7.8 5.6 13.9 14.6 5.6 12.1 8.5 3.7 11.2 2.6 16.2 15.4 9.4 11.5 4.1 8.5 1.7 7.2 2.6 4.0 7.1 5.6 8.5 6.3 6.9 10.7 5.1 7.7 5.5 0.7 5.6 6.5 11.1 8.0 5.9 14.3 17.0 15.3 18.8 13.7 14.3 15.7 18.2 19.7 14.2 RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165844-64372869 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 54.0" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 24.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favourable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" 8.1 8.1 9.9 3.1 12.8 1.6 6.3 6.0 13.0 10.1 7.1 5.5 20.1 3.4 12.7 11.8 6.9 8.1 7.3 10.4 7.4 10.6 12.4 7.2 6.1 3.4 9.4 9.3 12.0 6.6 54.0 16.1 2.0 10.7 11.5 3.0 11.3 7.3 16.4 4.4 6.6 3.2 15.0 11.0 5.1 5.0 8.1 7.1 0.0 20.6 2.5 2.4 10.9 7.9 2.4 1.0 4.2 1.8 2.0 4.2 0.3 0.0 0.1 1.3 0.0 0.0 0.0 0.3 1.1 0.5 1.1 0.6 0.0 0.1 0.0 0.1 0.8 0.2 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.2 0.1 2.6 0.0 0.1 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.5 1.3 0.1 3.3 24.9 1.8 0.3 0.3 0.1 0.0 0.3 0.0 1.3 0.1 0.1 0.0 3.2 0.1 2.8 0.0 0.0 0.0 0.5 0.0 3.5 3.0 1.8 4.2 1.9 0.6 2.5 1.4 3.0 3.2 0.6 2.4 4.2 3.9 2.6 2.0 0.8 1.0 1.8 0.3 9.9 12.8 6.0 11.7 7.4 10.6 9.4 9.3 10.7 7.1 RNF181 HSPC238 ENSG00000168894 "Ring finger protein 181" Q9P0P0 2 85595725-85597613 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046112, HPA062121" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA046112: , HPA062121: " "unprognostic (3.79e-1)" "unprognostic (8.31e-2)" "unprognostic (5.08e-2)" "unprognostic (2.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.67e-2)" "unprognostic (3.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.22e-2)" "unprognostic (5.85e-2)" "unprognostic (1.11e-1)" "unprognostic (4.96e-2)" "prognostic unfavourable (1.06e-6)" "unprognostic (3.24e-1)" "unprognostic (2.04e-1)" "prognostic favourable (4.59e-5)" "unprognostic (1.49e-2)" 32.9 41.5 42.2 26.4 36.2 32.8 40.4 19.0 38.7 34.4 40.5 33.0 36.0 34.5 28.1 44.5 40.2 33.3 34.8 52.4 34.5 32.9 57.8 85.1 36.0 33.1 41.2 29.3 31.6 85.1 21.8 20.2 50.7 36.0 34.2 35.4 32.1 42.1 45.7 47.0 30.4 46.5 33.2 42.2 37.2 35.7 36.3 31.3 31.0 43.7 39.2 42.6 43.8 29.4 53.2 80.2 78.6 94.7 39.3 54.4 83.3 32.2 32.7 25.5 27.6 26.1 32.3 41.2 27.3 53.8 58.3 55.4 49.9 34.3 30.8 53.7 40.5 30.3 22.0 43.7 62.7 35.0 27.1 23.4 16.9 59.9 45.8 25.9 32.1 33.7 58.1 38.8 65.0 48.4 27.4 32.1 78.6 51.7 24.4 60.3 17.8 49.4 26.1 53.6 43.7 54.4 30.1 15.2 20.1 23.1 33.6 44.8 33.3 34.3 41.8 28.6 20.4 57.2 38.9 44.8 37.3 38.6 44.7 39.1 25.1 40.4 94.7 71.6 40.7 69.3 37.7 53.2 42.6 39.1 71.0 44.3 36.7 36.8 78.6 39.3 51.8 80.2 54.4 83.3 42.2 36.2 19.0 38.7 34.5 32.9 41.2 29.3 36.0 31.3 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980302 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.9;brain: 17.6" "Cell line enhanced" "Detected in many" "HeLa: 36.3;RPTEC TERT1: 29.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" Nucleoplasm "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.2 0.7 7.6 0.6 6.2 12.9 1.2 16.6 17.6 1.2 0.7 7.5 2.0 0.8 1.6 2.5 1.0 2.7 0.9 1.0 11.0 7.3 2.6 0.5 5.7 0.8 6.8 8.5 1.1 3.6 0.5 2.0 2.9 14.3 0.9 0.6 2.2 1.9 4.7 0.9 0.8 1.1 1.0 5.1 0.5 0.6 7.0 2.9 0.0 3.0 0.0 0.4 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 5.2 0.0 1.8 2.2 0.3 2.6 3.6 7.4 7.1 0.1 0.0 0.0 0.0 2.8 0.0 6.1 0.0 13.5 0.0 2.0 0.1 36.3 0.0 0.0 0.0 0.0 1.2 0.0 11.3 0.1 0.1 0.2 0.0 5.1 0.0 0.0 0.9 2.9 10.1 1.5 1.2 0.4 29.1 0.0 6.3 6.0 0.2 0.0 10.2 0.0 1.0 2.7 9.0 1.9 0.1 6.0 0.0 0.0 0.0 6.1 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 6.2 16.6 12.1 11.0 7.3 6.8 8.5 14.3 2.9 RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 19.0;kidney: 9.5" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 20.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057675 Uncertain "HPA057675: " "unprognostic (1.23e-2)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "prognostic favourable (7.95e-6)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.98e-1)" "prognostic favourable (3.51e-4)" "unprognostic (5.50e-2)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (2.53e-3)" 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.2 0.2 1.2 19.0 5.1 1.2 6.2 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.8 0.3 6.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 3.7 4.3 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160183-31207019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favourable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 18.3 16.1 15.2 11.6 20.3 6.8 18.4 16.7 23.4 19.4 17.0 24.3 14.4 15.6 21.8 20.2 20.5 18.3 13.6 15.6 14.7 15.6 27.6 39.7 14.4 11.1 15.9 14.6 21.2 23.5 32.5 24.3 19.8 20.9 30.5 17.3 24.1 27.0 23.5 18.0 22.9 24.4 22.8 16.4 14.4 18.0 11.8 15.1 12.6 39.9 14.4 18.0 19.4 18.5 10.3 12.6 21.5 15.1 15.4 14.0 13.0 9.4 5.6 10.9 12.3 22.1 14.9 10.4 11.3 21.9 15.6 21.2 6.2 4.5 9.0 6.4 20.0 6.0 10.4 11.7 16.1 8.9 11.2 3.9 5.4 7.6 31.0 9.5 6.1 15.8 42.1 10.9 25.4 13.0 4.6 10.8 18.6 6.7 8.1 5.4 4.8 6.2 8.5 10.9 10.5 11.2 8.2 4.8 9.8 8.2 11.0 16.6 7.6 6.3 9.0 11.1 8.0 12.8 5.5 15.2 12.3 11.5 14.5 6.0 8.8 15.0 14.6 8.0 12.4 15.1 14.0 10.3 12.7 13.8 12.6 9.0 12.9 11.8 21.5 15.4 12.2 4.7 13.6 13.0 15.2 20.3 16.7 23.4 14.7 15.6 15.9 14.6 20.9 15.1 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487061-228495766 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 15.7 30.3 25.6 12.5 28.1 12.3 10.3 33.2 54.7 11.4 10.7 15.5 12.5 14.7 12.9 12.2 18.0 14.2 14.5 17.7 25.2 24.9 16.2 20.4 11.5 9.8 20.2 29.3 20.2 19.4 22.3 16.4 8.8 22.7 15.0 6.6 12.3 30.3 12.6 55.5 15.5 13.2 8.6 16.3 19.0 14.2 9.5 11.4 11.1 27.9 19.4 11.2 10.0 13.1 2.0 1.7 8.7 2.1 1.0 2.3 0.6 9.3 7.0 4.9 10.3 5.4 3.5 9.5 7.8 4.8 4.9 3.7 3.6 6.5 21.2 16.3 8.9 7.4 6.2 6.6 1.8 9.6 8.0 6.4 5.2 4.6 14.7 7.3 12.6 6.1 11.8 3.8 5.1 4.3 10.2 41.5 3.5 5.2 11.6 6.5 11.0 7.2 9.9 4.5 20.0 3.5 5.9 10.9 11.0 7.9 16.5 21.0 11.6 17.5 9.9 6.1 6.3 6.6 7.4 75.5 22.6 11.6 16.4 7.7 10.2 0.0 1.1 8.7 1.3 2.1 1.5 1.2 1.5 2.3 1.4 2.0 1.4 1.2 0.3 1.0 1.4 1.7 1.3 0.6 25.6 28.1 33.2 47.3 25.2 24.9 20.2 29.3 22.7 11.4 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavourable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favourable (3.28e-5)" 28.2 13.8 30.2 21.8 20.8 34.9 26.7 16.3 29.5 40.6 22.8 26.4 11.4 17.0 29.4 19.0 17.6 24.7 30.8 20.1 28.7 16.1 23.0 33.9 28.4 35.2 19.7 25.2 24.8 20.3 14.5 15.7 18.6 23.6 20.7 19.2 11.5 19.8 14.2 23.0 26.6 38.5 32.7 30.1 22.7 21.5 35.4 27.7 25.1 17.0 14.7 29.5 33.9 23.7 13.5 11.4 17.6 10.5 4.8 14.4 4.5 8.4 5.4 4.8 5.5 9.1 7.9 6.2 7.6 7.3 7.2 6.6 2.9 5.6 5.0 14.0 7.8 6.0 3.7 5.6 9.9 21.1 3.1 8.4 25.2 4.2 7.6 1.6 5.4 7.8 8.6 5.8 10.9 11.1 4.6 58.8 7.1 4.2 7.6 2.7 1.7 5.1 3.1 3.3 9.8 19.8 13.3 3.8 8.2 7.9 4.8 7.3 4.2 6.5 11.0 8.4 6.7 6.2 4.6 28.6 18.3 3.4 5.5 5.6 5.0 17.6 7.5 6.5 14.4 5.6 9.0 13.5 11.8 10.8 4.6 12.7 6.1 8.8 16.6 4.8 10.5 11.4 12.0 4.5 30.2 20.8 16.3 29.5 28.7 16.1 19.7 25.2 23.6 27.7 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964685 "Enzymes, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.7" "Cell line enhanced" "Detected in all" "Daudi: 38.4;Karpas-707: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049587 Approved Approved Cytosol Cytosol "HPA049587: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favourable (3.39e-4)" "prognostic unfavourable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favourable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 8.6 11.3 8.0 13.1 10.5 36.4 12.0 14.1 14.1 9.9 13.2 10.1 4.8 14.1 10.8 6.9 23.3 7.9 10.1 8.5 6.0 7.2 12.0 6.5 13.8 12.9 9.6 9.3 7.1 7.0 6.4 5.7 9.4 10.2 7.4 15.3 9.0 10.8 5.7 10.2 13.6 15.5 10.6 8.0 9.0 7.4 54.7 8.3 6.8 8.2 11.1 16.7 11.3 12.8 1.3 1.3 16.1 2.0 0.8 1.6 0.7 6.6 5.1 4.4 4.0 2.7 3.8 29.3 3.0 3.8 5.6 6.0 5.9 19.9 38.4 5.3 4.0 9.5 5.4 7.3 5.1 14.1 3.5 3.3 4.0 5.9 8.6 5.0 7.0 3.1 13.7 12.2 15.1 11.7 4.1 46.2 5.4 2.1 3.3 6.3 7.0 5.8 4.5 6.3 3.9 4.3 9.6 7.0 3.5 9.8 3.4 21.9 2.8 7.4 12.7 3.0 4.2 7.7 5.3 11.1 5.6 13.6 4.4 5.2 4.5 5.3 2.0 3.5 1.6 1.8 1.2 1.2 1.4 0.8 1.3 1.3 0.4 0.6 16.1 0.8 1.5 0.6 1.5 0.7 8.0 10.5 14.1 14.1 6.0 7.2 9.6 9.3 10.2 8.3 RNF2 "BAP-1, BAP1, DING, HIPI3, RING1B, RING2" ENSG00000121481 "Ring finger protein 2" Q99496 1 185045364-185102608 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026803 Uncertain Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA026803: AB_10602086" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (1.35e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.08e-5)" "unprognostic (5.85e-2)" "unprognostic (3.56e-3)" "unprognostic (1.62e-2)" "unprognostic (2.01e-2)" "unprognostic (5.51e-2)" "prognostic unfavourable (1.94e-7)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (9.89e-3)" "unprognostic (2.52e-1)" 17.8 15.0 14.3 13.9 12.4 15.3 29.7 15.6 23.6 16.6 12.0 7.8 20.7 10.4 16.2 12.6 15.2 11.5 13.1 12.0 16.0 13.1 13.7 11.1 16.7 20.7 9.4 10.4 19.9 15.0 12.3 26.5 28.4 11.4 13.2 13.5 10.1 17.3 20.6 13.1 12.5 9.8 14.8 11.2 16.2 12.2 27.8 9.4 17.2 15.1 11.5 16.1 17.6 16.9 14.7 19.9 20.6 22.1 17.4 19.4 12.0 13.9 7.7 28.5 11.3 8.1 13.9 27.1 9.9 12.6 15.7 12.6 12.3 23.4 4.2 12.4 12.1 4.9 19.5 14.3 19.1 12.2 10.2 22.5 4.7 10.7 11.9 23.0 12.7 13.0 8.8 12.8 16.5 15.7 17.8 10.0 11.3 8.7 19.9 6.8 38.2 4.2 22.9 17.7 4.0 11.9 9.9 8.4 14.4 6.9 4.2 20.2 8.8 12.4 11.1 11.3 14.7 10.7 12.6 16.5 10.7 15.6 7.0 10.9 12.6 19.3 17.0 20.6 13.5 21.1 19.4 14.6 12.5 12.6 19.9 14.7 12.8 12.6 7.9 17.4 22.1 10.0 13.2 12.0 14.3 12.4 15.6 23.6 16.0 13.1 9.4 10.4 11.4 9.4 RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533851-101563344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA051773" Supported Enhanced Nucleoplasm Nucleoplasm "CAB012478: , HPA051773: " "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" 16.4 17.1 24.6 17.0 24.9 12.1 17.7 24.4 26.3 18.6 16.4 27.7 15.9 10.1 18.3 18.7 20.4 19.1 13.2 24.1 22.3 22.1 20.5 14.4 14.9 15.5 25.2 20.7 21.1 19.5 31.5 23.1 15.1 30.0 21.6 16.1 16.8 16.2 17.7 32.0 16.3 12.5 23.6 28.8 17.0 13.9 28.2 25.8 21.2 22.0 15.3 18.6 21.1 19.0 13.0 12.5 21.0 23.5 13.8 18.6 10.4 9.5 24.4 14.1 15.4 17.4 13.8 12.0 16.8 13.5 16.8 14.8 14.8 10.2 21.2 9.0 12.9 24.4 16.3 14.2 17.3 22.2 7.5 11.4 22.3 14.8 12.8 19.5 13.7 13.5 15.3 14.8 19.3 9.8 10.8 12.6 18.2 12.5 15.1 5.2 31.1 12.4 14.6 48.8 10.5 6.9 9.2 15.1 19.0 23.7 12.7 13.8 11.4 9.2 13.9 15.6 15.7 11.1 14.0 13.6 42.0 11.7 13.8 7.4 18.9 21.0 12.7 19.1 18.6 17.5 14.0 13.0 15.4 13.9 12.5 11.2 16.2 14.9 13.9 13.8 23.5 7.9 11.9 10.4 24.6 24.9 24.4 26.3 22.3 22.1 25.2 20.7 30.0 25.8 RNF213 "C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavourable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 17.0 15.1 7.4 16.9 10.3 22.4 10.2 4.7 7.5 11.0 12.2 15.6 14.9 8.5 16.6 13.0 13.2 9.7 12.1 8.5 7.8 7.8 17.1 11.6 15.4 17.9 10.9 5.6 11.5 9.0 41.1 11.4 15.1 10.0 11.2 8.0 12.3 11.7 12.5 9.0 8.7 14.8 13.6 14.3 17.0 10.6 5.9 8.7 24.5 15.9 7.5 18.2 13.6 15.4 7.2 13.9 37.9 9.6 11.4 12.1 1.8 16.1 28.7 2.9 2.0 10.5 16.1 2.2 4.1 8.9 18.5 15.8 3.0 7.5 1.0 3.5 8.5 9.4 3.9 5.3 6.3 36.5 1.7 2.5 11.6 5.3 4.5 2.6 2.6 8.8 3.6 10.4 4.5 14.2 4.6 6.0 6.9 3.9 10.5 1.1 2.1 6.6 7.2 6.7 1.2 5.1 14.0 2.8 3.9 9.9 21.1 7.5 4.8 3.3 18.3 10.3 8.2 6.0 4.2 2.6 2.4 2.9 7.7 3.1 3.7 6.9 9.6 4.2 12.1 8.0 8.1 6.2 8.6 9.7 2.3 7.2 6.9 8.5 37.9 11.4 6.9 13.9 6.4 1.8 7.4 10.3 4.7 7.5 7.8 7.8 10.9 5.6 10.0 8.7 RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018955: AB_1858500, HPA021123: AB_1858501" "unprognostic (3.31e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.26e-4)" "unprognostic (2.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.40e-2)" "prognostic favourable (6.24e-5)" "unprognostic (2.88e-2)" "unprognostic (9.01e-2)" "unprognostic (3.49e-1)" "unprognostic (1.73e-2)" "unprognostic (1.06e-2)" "unprognostic (3.69e-3)" 16.9 14.9 22.0 18.8 24.8 22.2 18.4 33.5 27.8 17.8 26.9 22.0 13.4 11.5 26.9 13.3 18.7 19.6 14.2 29.1 20.5 17.4 12.7 11.8 14.9 23.8 23.8 14.8 25.6 21.3 23.2 24.9 14.6 20.4 17.7 11.8 18.9 16.2 21.5 22.5 15.1 20.1 25.0 18.7 23.3 18.3 34.3 26.3 18.5 19.8 9.6 24.1 17.7 30.7 8.8 6.7 24.5 8.4 10.0 9.7 6.5 14.4 15.6 12.8 21.8 15.3 13.3 8.8 15.5 16.3 16.1 14.9 11.3 8.3 12.7 8.0 17.3 10.4 13.3 10.9 13.2 7.9 11.6 9.8 9.5 11.4 18.4 16.0 16.8 13.7 14.0 12.3 15.1 12.7 19.6 8.9 17.8 22.2 6.0 25.5 17.6 13.0 15.3 18.1 7.1 9.6 12.2 9.8 15.6 9.8 24.6 8.8 9.7 16.4 13.8 16.3 29.4 16.6 13.9 7.2 5.4 10.3 12.2 14.9 25.9 1.3 7.7 24.5 9.0 8.4 9.0 7.3 7.9 6.7 6.7 8.8 9.7 9.1 13.1 10.0 7.7 5.4 7.0 6.5 22.0 24.8 33.5 27.8 20.5 17.4 23.8 14.8 20.4 26.3 RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962545-125092633 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 63.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 1.9;myeloid DC: 1.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavourable (1.92e-4)" 9.6 3.5 3.3 4.2 4.7 10.5 14.6 3.8 3.5 8.0 7.7 5.7 6.4 2.3 5.9 5.6 6.2 7.5 12.1 6.5 3.8 1.7 2.5 6.3 7.3 3.7 4.3 2.9 11.5 3.8 63.3 4.0 12.0 3.4 6.4 2.3 6.0 6.0 6.9 10.1 10.9 3.1 13.0 2.3 2.6 4.5 7.4 5.7 0.1 7.4 3.6 1.6 8.7 13.6 0.0 1.2 0.6 1.9 0.3 0.2 0.3 4.1 4.2 1.5 0.5 5.4 2.1 8.5 5.7 7.7 3.9 5.1 0.0 3.9 0.0 7.9 5.4 6.0 0.9 5.1 5.5 0.0 4.8 2.3 6.3 1.3 5.2 0.0 0.2 5.9 4.7 2.9 8.6 4.4 11.6 0.0 6.8 0.0 0.0 0.0 1.3 1.1 0.1 5.9 0.0 4.0 1.9 0.7 0.0 2.5 0.6 2.1 4.1 0.6 6.9 3.2 10.3 0.0 12.1 0.0 0.0 0.0 2.4 0.0 3.8 0.6 1.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.3 3.3 4.7 3.8 3.5 3.8 1.7 4.3 2.9 3.4 5.7 RNF220 "C1orf164, FLJ10597" ENSG00000187147 "Ring finger protein 220" Q5VTB9 1 44405194-44651724 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 57.4" "Cell line enhanced" "Detected in all" "U-937: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027577, HPA027578" Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA027577: , HPA027578: AB_10601482" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-2)" "unprognostic (2.56e-1)" "unprognostic (2.94e-2)" "unprognostic (6.96e-3)" "prognostic unfavourable (2.35e-6)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.13e-1)" "unprognostic (2.14e-3)" "unprognostic (2.96e-2)" "prognostic unfavourable (5.12e-4)" "unprognostic (1.51e-2)" "unprognostic (1.98e-1)" "unprognostic (1.37e-3)" "unprognostic (6.46e-2)" 9.8 7.4 20.9 9.6 38.5 12.7 6.7 12.6 40.1 5.4 9.2 40.7 2.7 10.7 8.0 8.8 6.0 9.3 4.5 9.2 33.4 20.9 7.4 5.1 7.4 7.6 49.8 19.8 9.5 8.1 7.0 5.7 8.7 25.8 7.7 5.9 4.2 9.3 7.1 28.4 8.7 8.8 8.0 57.4 7.9 7.6 7.0 49.6 5.0 7.3 4.6 8.0 7.9 5.6 3.6 6.6 2.8 2.3 1.9 4.3 1.4 5.9 2.8 12.3 4.2 4.8 4.4 9.3 7.1 6.5 5.5 8.1 4.9 5.9 11.6 6.3 5.6 3.9 13.8 5.8 7.5 14.4 12.2 16.0 8.9 8.3 7.8 11.3 8.2 4.8 13.3 6.1 9.8 3.1 11.7 5.8 3.4 4.1 11.1 8.6 13.4 6.5 9.4 7.3 8.3 3.5 3.7 5.6 6.9 6.0 4.2 8.6 3.1 20.0 4.8 5.8 6.2 5.4 13.1 13.2 12.7 8.4 4.8 36.5 3.5 2.4 2.3 2.8 3.2 1.8 2.4 2.4 1.0 4.3 3.4 3.6 1.9 1.7 1.5 1.9 1.3 6.6 3.2 1.4 20.9 38.5 12.6 30.8 33.4 20.9 49.8 19.8 25.8 49.6 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663864-218672411 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA036420: , HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 13.4 12.7 13.9 11.1 16.1 6.2 13.7 13.4 27.6 17.3 13.3 17.1 9.8 4.3 16.6 16.2 12.2 16.8 11.8 17.2 13.1 16.5 13.7 15.6 11.9 12.1 12.1 11.6 17.8 13.0 19.3 14.8 17.7 15.4 14.7 9.0 15.3 13.6 17.9 16.9 15.7 10.3 16.0 10.0 12.9 11.8 18.4 9.1 15.3 16.8 12.7 16.8 14.0 11.8 13.3 8.2 23.3 11.2 14.8 15.0 13.9 5.9 7.6 6.9 8.0 10.5 6.4 7.4 6.7 17.0 23.2 21.7 12.6 4.0 3.9 5.4 14.2 5.4 7.9 13.2 10.1 4.3 10.9 5.4 5.6 11.9 12.9 4.7 5.9 14.2 12.4 21.1 14.2 12.7 9.0 6.2 14.9 16.9 5.3 5.8 10.9 8.7 7.5 4.3 5.8 14.2 6.3 7.0 7.9 5.2 5.8 10.0 6.9 8.8 7.3 13.2 6.3 5.1 9.6 5.3 4.2 6.6 11.1 5.9 8.0 23.3 10.6 14.9 13.9 10.3 12.6 11.9 13.7 13.6 8.2 13.3 15.0 11.7 8.9 14.8 11.2 7.4 11.5 13.9 13.9 16.1 13.4 27.6 13.1 16.5 12.1 11.6 15.4 9.1 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337313 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavourable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favourable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavourable (7.73e-4)" 19.0 21.5 13.6 15.4 21.6 25.6 16.9 18.4 38.9 19.8 22.0 17.6 14.5 20.3 31.2 15.6 26.0 24.4 19.8 15.1 17.1 13.8 22.3 28.7 17.3 17.5 15.0 16.6 25.6 18.5 31.4 14.3 27.5 27.2 19.2 18.2 20.2 20.0 28.5 17.6 19.8 21.4 27.0 14.3 19.8 24.3 27.6 13.0 26.7 20.6 14.0 21.1 25.8 18.1 13.8 14.2 7.1 15.5 9.8 16.7 16.2 15.6 17.3 16.2 19.1 16.0 12.7 17.3 17.0 18.4 19.9 15.8 29.2 32.8 13.8 23.6 20.2 28.5 23.0 25.6 12.5 16.5 12.6 36.4 8.1 24.1 12.3 15.2 15.2 13.1 13.2 24.8 22.4 15.1 17.6 21.7 13.6 34.1 13.9 15.8 16.2 22.2 14.5 16.7 11.0 12.2 11.3 11.6 11.2 13.7 17.5 4.5 39.5 12.8 9.9 24.1 16.1 12.6 15.5 5.2 8.5 0.1 8.0 25.8 18.7 7.1 15.5 3.9 16.7 14.5 11.0 9.0 12.7 14.5 14.2 13.8 14.5 12.4 1.1 9.8 14.1 8.1 6.6 16.2 13.6 21.6 18.4 38.9 17.1 13.8 15.0 16.6 27.2 13.0 RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160661 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol Cytosol "CAB009063: AB_2127706, HPA048745: " "unprognostic (3.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (9.05e-2)" "unprognostic (2.52e-1)" "unprognostic (6.24e-2)" "unprognostic (9.09e-3)" "unprognostic (1.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (6.21e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" 14.4 18.5 11.7 21.5 17.4 20.0 15.1 20.0 26.4 17.7 17.3 18.4 19.9 13.4 22.4 22.3 15.4 17.4 17.2 14.5 10.7 9.8 17.2 14.8 15.3 19.3 11.0 18.0 20.6 23.6 20.0 19.2 18.7 13.4 16.4 14.1 16.9 19.6 23.1 39.5 29.1 16.1 19.7 9.1 27.3 16.5 21.8 11.0 33.6 17.4 13.1 24.9 16.3 13.5 2.4 4.6 3.8 3.7 2.5 4.8 1.3 4.4 10.3 9.7 12.0 6.6 6.9 19.7 7.8 11.5 15.3 12.2 9.4 11.2 8.8 4.9 11.0 7.6 5.5 11.0 9.1 9.3 4.2 8.2 10.6 20.6 10.8 13.8 14.7 12.5 9.5 6.9 10.9 9.7 4.8 11.7 6.8 13.8 13.0 8.1 5.2 11.3 8.8 7.2 5.6 7.8 18.4 8.6 10.8 7.1 18.9 9.4 6.6 10.2 9.5 10.8 8.2 7.8 7.3 15.6 13.8 8.6 4.1 5.5 10.0 0.0 2.1 1.5 1.9 3.7 4.8 2.4 1.9 2.1 1.8 1.1 2.3 1.3 3.8 2.5 2.1 4.6 3.0 1.3 11.7 17.4 20.0 26.4 10.7 9.8 11.0 18.0 13.4 11.0 RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400041-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA074151: " "unprognostic (3.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.90e-1)" "unprognostic (6.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.55e-2)" "prognostic unfavourable (6.72e-8)" "unprognostic (3.39e-1)" "unprognostic (9.99e-2)" "unprognostic (1.60e-2)" "unprognostic (5.87e-3)" "unprognostic (2.80e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.55e-3)" "prognostic favourable (3.02e-4)" 11.9 10.6 18.2 19.6 23.4 10.4 12.3 25.2 26.9 11.2 17.3 21.5 10.0 17.0 15.0 12.7 14.4 11.7 15.5 16.0 17.6 17.7 10.8 11.1 11.6 27.2 19.3 19.4 14.0 12.2 11.1 17.1 10.2 19.3 10.2 14.2 12.7 12.4 12.9 45.7 13.8 16.0 15.0 21.3 19.4 16.3 20.8 17.2 21.7 12.7 9.1 22.5 16.4 11.5 31.8 16.9 36.5 20.3 29.9 42.8 25.8 18.4 22.4 14.6 15.3 11.6 10.7 18.4 19.7 17.7 19.7 15.1 27.7 7.1 26.6 15.2 21.2 13.4 22.0 12.4 17.6 38.7 13.0 30.8 15.5 25.4 14.0 26.5 21.7 9.5 16.8 17.1 14.9 20.6 23.2 12.5 19.3 14.6 23.3 38.9 18.8 20.4 22.3 19.2 15.6 13.6 22.1 21.7 14.1 24.8 9.3 15.0 16.1 20.2 16.5 17.0 12.3 14.7 15.5 22.2 36.7 29.0 12.1 18.7 17.0 26.9 17.9 36.5 32.4 19.9 33.0 31.8 37.8 34.1 16.9 25.5 32.8 32.6 27.4 29.9 20.3 14.3 42.8 25.8 18.2 23.4 25.2 26.9 17.6 17.7 19.3 19.4 19.3 17.2 RNF38 ENSG00000137075 "Ring finger protein 38" Q9H0F5 9 36336396-36487548 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015853 Approved Supported Nucleoplasm Nucleoplasm "HPA015853: AB_1856365" "unprognostic (2.26e-1)" "unprognostic (2.49e-1)" "unprognostic (1.53e-1)" "unprognostic (8.16e-2)" "unprognostic (6.49e-2)" "unprognostic (3.65e-3)" "unprognostic (3.30e-3)" "unprognostic (1.64e-2)" "unprognostic (1.58e-1)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "prognostic favourable (2.90e-6)" "unprognostic (3.88e-2)" "unprognostic (5.94e-2)" "unprognostic (1.46e-1)" "unprognostic (5.39e-2)" 11.9 8.0 13.1 7.7 14.5 20.3 11.1 18.8 17.0 13.6 14.1 12.2 8.1 6.4 16.3 12.9 10.1 11.7 9.6 9.5 10.0 11.1 12.3 6.8 11.7 14.5 9.2 12.3 24.4 12.8 12.2 5.7 21.2 14.0 15.3 10.1 14.4 10.3 12.8 9.6 8.9 10.2 16.9 8.5 11.4 8.7 46.3 10.0 13.1 14.4 4.3 11.1 16.5 13.5 6.2 4.1 12.2 4.3 8.4 8.7 4.2 9.3 5.3 20.6 12.2 9.5 8.8 20.2 5.8 7.4 7.2 9.5 9.0 5.2 14.1 6.2 11.3 3.7 13.1 6.9 11.2 12.5 5.6 17.0 7.5 8.8 7.4 12.5 15.6 9.0 7.4 9.1 8.8 18.3 3.5 13.6 11.6 3.2 12.8 6.6 13.8 3.8 11.8 9.3 7.8 12.3 10.8 8.6 9.3 6.6 6.7 6.6 6.4 12.8 18.0 6.9 10.5 4.0 6.9 9.0 18.7 10.0 6.3 10.6 8.8 12.2 4.3 7.2 7.2 4.1 6.0 5.8 6.5 7.6 4.1 6.2 7.0 7.0 8.0 8.4 4.1 3.3 8.7 4.2 13.1 14.5 18.8 17.0 10.0 11.1 9.2 12.3 14.0 10.0 RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2625320 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: " "unprognostic (8.38e-3)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (9.31e-3)" "unprognostic (9.03e-3)" "prognostic unfavourable (6.38e-4)" "unprognostic (1.34e-1)" "unprognostic (6.79e-2)" "unprognostic (2.58e-1)" "unprognostic (5.64e-2)" "unprognostic (1.93e-2)" "unprognostic (6.40e-2)" "unprognostic (4.70e-2)" "unprognostic (8.67e-2)" "unprognostic (1.54e-1)" 28.6 29.1 25.4 32.2 39.4 36.4 28.6 35.9 50.3 28.2 25.1 34.8 28.4 27.0 32.2 28.0 30.3 27.8 27.1 24.6 22.7 22.8 32.3 25.6 27.4 41.9 23.5 23.4 32.1 31.0 31.2 30.0 29.4 36.7 28.5 26.7 29.2 36.1 28.5 26.0 28.5 29.3 31.8 23.1 41.9 28.9 36.8 23.7 50.4 29.3 19.1 51.5 27.7 26.3 36.9 35.3 41.8 39.9 39.7 43.7 45.8 19.8 18.9 19.8 13.8 17.2 18.0 22.1 24.3 27.4 25.9 23.5 21.4 18.8 25.2 14.5 24.5 13.0 20.9 19.0 24.7 11.8 12.6 30.5 19.5 20.4 25.9 21.4 26.7 20.8 23.1 24.0 20.1 23.9 16.1 34.9 26.4 13.6 34.3 29.9 30.4 23.7 25.0 18.8 13.0 17.6 25.4 18.4 17.4 17.0 13.3 16.9 21.0 16.2 19.9 22.6 11.1 21.3 37.2 45.2 60.1 27.9 22.0 23.4 23.4 14.6 29.6 41.8 43.7 39.3 43.7 36.9 37.5 43.0 35.3 27.2 36.2 36.3 32.9 39.7 39.9 23.6 39.9 45.8 25.4 39.4 35.9 50.3 22.7 22.8 23.5 23.4 36.7 23.7 RNF40 "BRE1B, KIAA0661, RBP95, STARING" ENSG00000103549 "Ring finger protein 40" O75150 16 30761745-30776307 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041330, HPA054227" Approved Supported Nucleoplasm Nucleoplasm "HPA041330: AB_10793872, HPA054227: " "unprognostic (1.61e-1)" "unprognostic (1.74e-2)" "unprognostic (3.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.21e-1)" "unprognostic (4.01e-1)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "prognostic favourable (8.11e-8)" "unprognostic (9.96e-2)" "unprognostic (1.36e-1)" "unprognostic (6.55e-3)" "unprognostic (6.60e-3)" 21.0 25.2 26.4 21.3 26.5 40.8 20.9 36.8 28.2 25.8 21.0 22.0 18.0 20.1 28.4 17.0 25.6 24.4 21.3 22.8 22.2 17.1 20.0 21.2 20.2 21.9 20.9 18.9 30.5 24.4 44.0 21.6 25.3 19.6 21.4 15.1 20.0 27.3 21.1 20.0 25.5 20.3 18.3 18.6 20.0 19.6 43.1 22.8 23.5 26.8 15.4 20.6 22.5 21.4 7.6 12.0 15.0 14.9 9.9 13.3 12.9 20.3 31.9 19.4 18.4 14.8 15.5 21.2 20.8 16.1 24.1 18.8 25.7 19.0 16.2 30.6 17.8 22.1 35.3 18.5 18.9 23.2 41.4 15.8 35.0 26.7 19.8 27.4 18.6 14.4 15.5 30.2 17.1 20.2 34.8 15.5 14.6 34.0 26.1 25.7 20.2 19.3 51.9 21.4 31.2 10.6 18.1 32.4 23.8 16.3 20.9 15.0 32.0 31.2 21.8 27.1 13.8 19.1 23.7 23.1 28.5 32.2 22.5 24.4 27.6 6.2 11.5 14.7 12.9 13.4 13.3 7.6 7.2 9.9 12.0 6.5 5.4 8.3 15.0 9.9 14.9 6.2 6.2 12.9 26.4 26.5 36.8 28.2 22.2 17.1 20.9 18.9 19.6 22.8 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202175-56221933 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favourable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 22.2 17.6 18.6 11.8 30.2 12.0 14.3 30.9 47.1 16.2 15.0 16.9 12.3 8.5 16.4 9.7 16.5 17.7 18.0 22.6 17.3 22.4 14.1 10.5 16.5 14.8 15.3 18.2 17.0 16.0 17.9 16.7 14.6 25.3 25.2 13.6 14.6 10.5 15.6 21.2 10.1 10.8 20.3 11.8 13.5 12.2 10.1 12.1 11.3 20.5 10.1 17.0 16.2 11.5 24.6 13.1 41.1 11.5 13.4 12.5 12.3 7.5 11.6 12.6 20.0 26.5 19.3 9.4 25.3 25.1 22.8 18.5 14.2 9.9 14.6 13.5 21.4 8.7 17.0 12.2 16.6 15.2 9.3 19.6 8.3 8.1 55.6 21.4 21.4 24.6 28.7 19.0 33.6 22.1 13.8 15.0 12.6 12.2 12.2 9.6 15.2 13.6 13.3 9.1 8.8 12.1 11.1 23.1 14.0 22.1 12.7 20.0 17.8 25.2 13.3 11.5 12.3 14.8 9.7 10.8 12.4 13.3 13.7 12.9 13.7 21.0 11.5 41.1 12.5 11.4 11.2 22.7 10.6 10.9 13.1 24.6 11.0 11.2 15.8 13.4 11.2 10.2 12.1 12.3 18.6 30.2 30.9 47.1 17.3 22.4 15.3 18.2 25.3 12.1 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58352500-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 14.9;Hep G2: 29.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.7" "Region enriched" "Detected in many" 7 "cerebellum: 30.6" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008079 Uncertain "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favourable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.4 9.4 2.2 6.2 3.5 1.9 4.5 30.6 4.3 3.4 26.4 0.9 21.3 18.5 1.7 9.1 10.0 3.9 8.1 3.3 1.9 1.3 8.0 7.0 6.1 2.7 0.8 1.1 1.6 13.2 3.0 13.3 8.7 4.1 8.0 16.3 3.8 13.7 19.0 0.5 8.9 29.0 0.9 0.8 0.9 4.9 3.1 0.7 3.0 1.8 5.7 6.6 4.0 4.4 0.9 1.1 1.7 1.8 5.6 3.6 1.2 0.7 10.4 1.9 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 14.9 5.0 4.2 5.3 0.0 2.9 0.4 4.0 0.0 8.8 7.3 3.4 0.5 29.2 0.0 4.2 3.0 0.0 8.2 0.0 1.3 0.0 0.3 3.6 0.0 0.1 2.2 3.9 0.3 0.7 6.9 0.0 2.2 3.7 5.6 1.2 0.3 0.9 0.4 0.3 1.3 1.2 0.0 0.1 1.2 0.0 0.0 3.8 1.7 3.3 0.4 0.4 2.4 1.7 0.2 1.6 3.1 0.8 3.2 0.9 2.5 3.6 0.4 0.9 2.3 3.0 0.8 5.6 1.8 1.1 1.2 1.2 2.2 3.5 30.6 4.3 1.9 1.3 0.8 1.1 4.1 0.7 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178354-32180793 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: " "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favourable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 9.8 20.6 19.3 9.0 20.6 10.3 14.0 13.6 16.8 11.3 25.7 17.4 14.7 18.1 12.3 14.6 15.9 16.9 13.9 19.2 16.9 12.0 32.7 38.1 14.7 11.6 16.3 14.2 19.0 19.3 7.2 5.8 23.4 12.3 13.1 19.1 12.2 25.3 15.3 24.5 13.4 36.7 13.7 19.7 10.2 14.2 9.6 9.6 10.8 18.0 14.2 12.5 13.2 9.9 6.7 26.9 7.2 6.4 7.5 7.0 6.5 5.2 6.8 4.6 17.8 5.1 3.5 3.6 2.1 2.7 4.6 5.3 9.1 4.4 6.8 7.7 5.1 4.3 8.6 4.8 4.9 4.2 11.7 5.4 7.7 18.7 6.0 0.0 11.1 3.5 6.5 7.8 5.9 9.3 13.9 7.4 6.7 7.4 6.6 15.6 0.0 2.9 4.5 5.3 9.5 13.1 3.3 4.8 10.0 4.1 4.5 4.6 9.3 19.1 4.2 5.2 5.0 0.0 8.1 4.0 6.1 8.0 3.6 12.1 3.0 5.1 4.6 7.2 7.0 6.4 6.1 6.7 5.7 6.2 6.6 6.0 6.4 6.3 2.4 7.5 4.5 26.9 5.7 6.5 19.3 20.6 13.6 16.8 16.9 12.0 16.3 14.2 12.3 9.6 RNF6 DKFZp686P0776 ENSG00000127870 "Ring finger protein 6" Q9Y252 13 26132115-26222493 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039343, HPA040048" Approved Supported "Nuclear membrane" "Nuclear membrane" "HPA039343: AB_2676456, HPA040048: AB_10672969" "unprognostic (3.22e-1)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.45e-1)" "unprognostic (1.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-2)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "unprognostic (7.63e-2)" "unprognostic (6.13e-2)" "unprognostic (1.39e-1)" "unprognostic (4.21e-2)" "unprognostic (2.70e-2)" "unprognostic (8.35e-3)" "unprognostic (1.84e-1)" "unprognostic (7.70e-2)" "unprognostic (8.47e-2)" 16.4 19.8 22.3 15.9 27.5 25.1 24.2 26.6 28.9 13.1 16.4 8.1 20.3 15.5 13.0 13.0 20.9 13.4 12.5 17.9 20.4 17.3 16.9 17.5 14.5 18.4 15.8 22.6 10.9 14.2 17.9 26.3 23.3 16.8 15.2 17.2 8.1 16.1 13.5 24.8 15.5 21.0 14.3 16.7 16.6 15.1 28.7 14.5 23.6 16.1 14.4 20.7 14.1 19.5 13.5 12.5 24.6 15.0 13.3 13.2 9.2 12.6 11.1 4.2 6.2 14.7 11.6 9.5 21.7 17.8 14.1 10.0 13.9 16.3 22.7 10.9 20.6 17.0 11.8 17.6 23.5 21.7 7.4 24.7 9.4 11.9 23.1 25.8 26.1 10.9 34.4 15.8 33.9 14.1 9.5 0.0 21.8 11.3 14.4 15.1 3.4 7.8 11.5 16.4 8.9 17.4 16.7 7.7 4.7 11.6 21.3 20.6 8.1 25.4 18.4 12.2 7.4 16.3 15.5 5.8 5.4 13.6 11.1 14.8 15.9 24.6 10.1 23.7 11.9 13.1 12.8 13.5 13.0 13.2 12.5 9.4 13.2 11.2 7.1 13.3 15.0 6.5 13.1 9.2 22.3 27.5 26.6 28.9 20.4 17.3 15.8 22.6 16.8 14.5 RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353972-37394738 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA050731: , HPA064925: " "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavourable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavourable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavourable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" 8.0 11.7 13.1 8.2 17.8 8.9 11.5 25.7 18.7 9.2 9.5 10.6 6.8 6.9 13.5 5.7 18.3 12.0 8.8 17.6 13.4 14.8 11.8 7.5 10.8 8.3 12.0 16.0 13.2 6.5 11.9 16.4 10.2 13.7 8.6 8.2 8.0 10.2 11.9 15.2 9.9 8.4 10.7 9.6 7.7 7.6 19.8 13.8 6.6 8.0 9.4 13.3 12.9 15.2 8.8 8.3 2.6 8.1 7.6 10.8 5.5 6.5 3.9 9.5 11.3 7.7 11.1 2.7 6.8 8.4 12.9 14.2 5.8 3.7 8.1 4.2 6.6 6.2 13.2 8.6 13.6 8.5 12.8 14.0 6.9 8.7 4.4 7.4 10.3 5.5 8.3 7.7 9.0 12.4 9.4 2.8 7.4 4.3 9.0 9.2 6.6 5.2 7.1 8.8 5.6 6.6 4.6 18.8 6.3 5.1 5.8 9.4 5.2 7.3 5.6 8.5 7.6 8.0 10.0 8.4 11.1 40.0 4.2 10.6 9.8 1.0 4.6 2.6 10.8 6.0 10.0 8.8 8.1 10.2 8.3 6.0 7.1 9.4 0.6 7.6 8.1 3.6 9.3 5.5 13.1 17.8 25.7 18.7 13.4 14.8 12.0 16.0 13.7 13.8 RNFT1 PTD016 ENSG00000189050 "Ring finger protein, transmembrane 1" Q5M7Z0 17 59952240-59964761 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013739 Approved Nucleoli Nucleoli "HPA013739: AB_1856382" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "prognostic favourable (6.57e-4)" "unprognostic (3.04e-2)" "unprognostic (6.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-2)" "prognostic favourable (7.48e-4)" "unprognostic (5.42e-2)" "unprognostic (3.45e-1)" "unprognostic (8.26e-3)" "unprognostic (9.44e-3)" "unprognostic (1.19e-3)" "unprognostic (1.44e-2)" "unprognostic (2.05e-1)" "prognostic favourable (2.57e-4)" "unprognostic (2.60e-1)" 7.9 6.2 2.8 5.3 4.3 3.8 4.2 5.1 3.7 3.1 4.0 2.4 3.7 5.3 2.7 8.1 4.6 3.2 3.1 4.1 3.1 2.2 4.7 12.0 5.0 4.4 2.9 3.1 3.5 7.5 4.7 6.1 4.4 3.4 4.5 4.8 4.2 5.1 3.0 6.7 2.7 7.6 3.0 3.4 4.1 3.9 45.5 3.0 5.9 6.1 4.3 6.0 5.1 3.7 9.5 10.1 20.2 17.1 8.9 7.7 7.9 4.8 2.2 2.3 3.1 7.6 5.7 4.5 6.2 3.3 4.8 6.0 6.9 1.9 7.2 10.4 5.1 5.6 7.2 4.7 8.4 6.8 7.8 6.0 5.8 6.2 5.6 9.3 9.3 6.3 2.5 4.5 2.0 4.9 17.3 4.4 4.1 6.2 3.8 4.5 0.9 5.1 5.2 17.4 4.1 3.9 3.4 1.4 2.7 8.9 2.1 12.3 10.2 17.8 3.5 9.4 8.4 5.5 5.2 6.5 18.0 4.2 6.5 5.2 4.7 17.3 11.8 20.2 5.6 13.9 7.7 9.5 5.2 6.3 10.1 6.1 6.8 6.1 5.7 8.9 17.1 6.7 6.5 7.9 2.8 4.3 5.1 3.7 3.1 2.2 2.9 3.1 3.4 3.0 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.6 8.6 13.5 17.1 7.9 8.4 8.1 12.9 8.5 10.5 13.3 9.8 4.3 14.6 10.6 9.2 7.1 15.7 10.4 19.4 19.8 12.3 19.0 7.8 7.8 6.5 20.3 10.8 5.3 9.2 10.9 10.6 9.3 18.7 11.8 15.6 7.5 8.9 14.5 8.1 7.6 17.7 20.9 8.3 9.4 8.8 7.9 11.4 10.7 6.5 7.0 7.0 20.4 7.3 8.5 7.9 9.6 17.4 10.7 18.7 8.2 12.5 15.2 15.5 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 RNMT RG7MT1 ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764558 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "HPA039409: AB_10795289" "unprognostic (3.02e-1)" "unprognostic (1.07e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (3.04e-1)" "unprognostic (6.17e-3)" "unprognostic (1.43e-1)" "unprognostic (3.76e-2)" "unprognostic (1.42e-3)" "unprognostic (9.45e-2)" "unprognostic (9.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-2)" "unprognostic (1.78e-1)" 18.9 10.1 13.3 12.7 20.4 40.1 16.6 19.7 27.3 14.0 11.5 10.3 12.1 9.1 15.4 13.1 12.6 12.2 9.9 21.2 14.9 18.2 12.9 12.0 12.4 14.6 14.5 21.8 19.6 13.3 16.6 21.2 16.1 28.5 14.7 11.6 10.8 12.8 12.2 29.1 14.3 11.3 15.1 16.1 12.3 11.4 17.1 12.6 12.2 19.2 15.8 15.8 26.5 11.4 20.1 20.8 21.6 13.1 9.4 15.7 4.1 11.4 6.8 13.2 9.9 9.8 12.5 9.2 9.4 11.7 9.8 13.3 8.0 5.5 12.8 11.6 9.6 4.6 15.5 13.5 16.6 7.1 8.3 9.6 7.0 7.5 10.8 25.0 8.2 9.5 14.7 10.3 29.1 7.5 14.4 12.9 11.1 7.1 15.9 9.0 10.1 5.3 10.4 13.9 17.4 9.0 9.0 10.2 15.3 10.6 7.8 18.1 6.8 10.5 7.7 19.7 27.7 16.0 10.0 26.0 28.3 26.6 14.5 9.6 9.8 21.6 13.1 8.5 12.5 10.3 10.1 16.2 11.9 10.3 8.1 20.1 15.7 12.2 7.1 9.4 11.4 20.8 12.8 4.1 13.3 20.4 19.7 27.3 14.9 18.2 14.5 21.8 28.5 12.6 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111851 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved 240000 "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: " "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavourable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 19.3 9.7 9.7 16.3 9.7 40.0 15.1 18.3 11.0 13.9 12.6 7.1 14.4 10.1 16.0 14.9 13.3 14.4 11.7 11.9 10.3 5.6 10.5 9.2 17.0 20.5 10.1 6.0 13.7 9.5 11.2 12.2 11.5 10.3 14.2 9.4 9.5 9.4 9.8 7.9 8.5 11.6 27.7 10.7 17.3 12.0 6.6 12.4 24.8 10.9 9.6 11.2 17.9 21.0 5.4 5.3 17.9 5.0 2.6 5.1 2.0 6.4 4.0 4.0 3.9 7.6 8.2 6.6 9.0 4.4 4.0 4.4 6.7 2.8 8.0 6.5 10.6 5.3 3.6 5.2 8.1 11.3 4.2 6.4 7.4 2.9 3.9 17.5 10.0 5.9 4.8 6.0 4.9 6.1 3.6 8.3 4.7 4.1 8.2 3.8 3.4 6.8 11.7 4.7 3.1 3.9 6.0 4.7 3.7 7.2 4.9 3.6 4.8 6.7 10.1 8.1 6.7 7.3 7.3 11.4 5.1 9.2 6.1 7.5 5.0 2.8 5.0 6.3 5.1 3.1 4.1 3.7 3.8 3.9 4.0 5.4 3.7 3.6 17.9 2.6 3.6 5.3 3.2 2.0 9.7 9.7 18.3 11.0 10.3 5.6 10.1 6.0 10.3 12.4 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179761-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol 3700000 Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavourable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 26.9 7.8 14.6 9.5 21.9 4.4 21.4 26.1 26.4 16.6 16.5 5.6 8.6 12.3 22.4 11.0 12.4 13.2 11.9 12.3 13.4 7.6 11.4 12.3 16.7 6.8 7.2 16.7 15.1 8.6 12.9 14.8 18.4 10.3 14.4 20.3 5.6 10.3 14.4 28.0 8.7 13.8 42.9 7.1 12.6 10.7 5.8 9.6 5.9 10.5 5.1 6.2 22.1 20.8 2.5 3.0 3.6 2.2 3.5 3.3 0.9 6.5 15.9 13.2 12.9 23.8 16.7 8.4 15.5 14.5 10.1 10.7 15.0 14.3 8.2 9.2 24.5 7.3 9.5 8.9 16.0 11.7 5.7 16.4 27.4 30.0 8.6 9.1 4.7 13.0 5.7 12.4 8.9 16.1 14.2 3.3 15.0 5.5 6.7 4.7 7.3 9.8 8.1 29.0 2.6 5.5 18.5 6.2 6.6 30.4 10.6 10.6 4.3 5.1 21.9 20.9 15.1 8.3 13.6 2.6 3.2 7.3 9.0 10.8 29.1 3.6 1.8 1.7 2.7 2.2 3.3 1.6 2.2 1.8 1.3 2.5 1.9 2.1 3.0 3.5 1.7 3.0 1.8 0.9 14.6 21.9 26.1 26.4 13.4 7.6 7.2 16.7 10.3 9.6 ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950162 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 12.0;HHSteC: 31.7;HSkMC: 26.4;U-266/70: 18.3;U-266/84: 12.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "pons and medulla: 6.6" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 3.9" "Lineage enriched" "Detected in single" 6 "T-cells: 3.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 13.5" HPA021868 Uncertain "HPA021868: AB_1856406" "unprognostic (9.38e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.76e-2)" "unprognostic (2.66e-1)" "prognostic unfavourable (9.86e-7)" "unprognostic (2.16e-3)" "unprognostic (9.13e-2)" "prognostic unfavourable (4.28e-8)" "unprognostic (1.25e-2)" 4.4 4.3 0.7 5.3 1.1 0.0 3.6 0.2 0.8 23.4 20.7 2.9 11.1 1.9 29.1 9.1 8.0 8.1 18.7 8.5 1.0 0.9 2.0 0.5 4.2 0.7 0.3 0.0 19.1 3.1 20.3 1.3 7.1 6.6 20.3 2.1 11.0 1.2 13.1 1.1 2.9 6.2 30.0 0.3 4.7 10.5 5.2 0.3 2.6 7.9 1.9 3.3 23.7 18.1 0.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 12.0 0.0 2.6 0.2 3.4 0.2 3.1 2.0 3.8 0.0 0.0 0.0 0.0 0.6 0.1 2.5 0.0 0.8 0.0 2.0 0.0 9.2 0.0 31.7 0.0 0.0 26.4 0.0 2.7 0.0 0.0 6.6 0.0 0.0 0.2 0.0 1.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.5 0.2 0.0 0.0 7.1 0.1 0.0 0.0 2.4 1.0 0.0 18.3 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.8 1.0 0.9 0.3 0.0 6.6 0.3 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117288300-117425855 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 38.6;lung: 20.2" "Group enriched" "Detected in some" 5 "HSkMC: 9.3;hTCEpi: 19.3;LHCN-M2: 13.4" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 7.4;olfactory region: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles Vesicles "HPA049098: , HPA072424: " "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.3 0.2 0.2 0.0 0.4 0.0 0.2 0.2 7.4 0.2 0.4 0.0 7.9 0.0 0.2 38.6 0.2 0.2 0.0 0.2 0.2 0.2 0.4 0.2 20.2 0.0 0.2 2.5 0.2 0.2 0.0 0.3 0.7 0.0 0.2 0.3 0.0 0.2 2.3 0.2 0.7 0.3 0.0 0.2 0.2 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 9.3 19.3 0.2 1.7 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.8 0.0 2.3 1.5 0.1 1.8 0.0 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 7.4 0.2 0.2 0.2 2.5 0.0 0.0 RPS6KA1 "HU-1, p90Rsk, RSK, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 45.2" "Cell line enhanced" "Detected in many" "HMC-1: 29.6;U-937: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 60.4" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favourable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favourable (1.84e-4)" "prognostic favourable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favourable (8.33e-4)" 11.0 8.2 6.3 24.2 9.7 15.8 5.0 14.4 6.3 4.9 23.2 11.1 4.4 24.5 2.1 3.6 8.9 6.0 8.0 3.4 5.3 5.1 13.6 5.4 26.1 32.7 10.3 3.5 2.1 10.1 10.0 7.4 3.3 8.6 8.6 15.8 3.6 19.0 5.5 1.1 9.0 45.2 2.8 7.9 27.0 9.7 2.7 9.0 15.9 13.9 4.9 17.3 6.2 4.5 5.0 22.0 40.1 18.0 7.9 8.3 17.1 9.7 3.4 2.8 3.7 0.1 0.0 3.7 0.8 1.5 4.2 4.0 4.0 8.1 18.3 4.5 0.5 11.5 6.3 22.7 3.0 15.1 4.1 20.1 8.5 7.0 1.3 23.7 29.6 0.7 8.3 3.8 6.9 1.8 3.4 6.7 0.2 5.4 0.8 23.3 7.2 11.0 12.6 3.6 8.0 12.0 2.7 4.1 1.6 6.9 6.6 3.2 4.2 20.3 1.2 0.2 5.3 0.7 3.3 4.1 4.9 10.0 2.5 31.8 4.0 9.6 18.0 40.1 8.3 16.4 6.9 4.9 6.1 7.3 22.0 5.0 3.9 5.5 34.5 7.9 17.3 8.6 6.0 17.1 6.3 9.7 14.4 6.3 5.3 5.1 10.3 3.5 8.6 9.0 RPS6KA2 "HU-2, RSK, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.2;ASC TERT1: 39.0;HHSteC: 39.5;HSkMC: 35.1;hTERT-HME1: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "eosinophil: 17.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: , HPA054237: " "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavourable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favourable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 15.4 6.5 26.8 5.3 35.5 6.9 12.7 12.1 21.5 13.5 7.1 20.3 11.5 4.3 18.3 5.2 14.0 11.9 12.5 40.9 25.0 18.3 9.9 3.3 24.6 10.6 22.4 18.4 20.9 30.2 32.6 18.0 12.1 22.7 10.6 7.4 11.1 9.0 10.5 14.4 7.5 7.2 15.8 37.2 16.5 10.4 5.1 25.7 0.8 24.8 3.5 4.9 15.5 10.2 0.4 3.9 17.5 1.6 3.3 0.6 0.2 2.1 0.0 4.3 6.2 53.2 39.0 0.0 4.6 8.9 2.5 3.6 0.0 1.3 0.2 1.5 16.1 1.9 2.2 9.9 2.3 0.9 0.5 0.0 9.4 0.1 39.5 0.1 1.7 35.1 7.1 13.7 42.4 13.9 0.0 0.0 10.4 0.4 0.2 0.4 1.1 2.5 0.7 2.2 6.2 2.7 2.3 2.4 16.8 1.6 4.3 5.8 0.1 3.3 5.1 9.1 0.9 25.1 1.3 1.2 1.8 0.6 6.0 0.2 8.6 0.1 0.5 17.5 0.5 0.7 0.2 0.3 0.5 0.2 0.7 0.4 0.6 0.3 0.4 3.3 1.6 3.9 0.4 0.2 26.8 35.5 12.1 21.5 25.0 18.3 22.4 18.4 22.7 25.7 RPS6KA3 "CLS, HU-3, MRX19, RSK, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 19.7 12.5 9.9 23.0 12.5 8.2 16.5 15.2 12.1 11.4 23.2 4.4 22.1 13.7 12.4 10.1 13.6 12.7 15.7 21.3 9.7 8.8 14.1 25.8 21.6 34.0 9.9 10.0 12.7 14.0 36.6 9.8 11.0 10.2 14.5 18.8 7.7 14.3 11.3 45.2 11.7 23.7 16.1 11.7 25.8 11.8 4.8 9.7 29.4 13.5 15.0 18.2 20.3 19.0 4.2 8.6 12.5 6.9 8.3 11.3 2.7 12.6 22.2 8.4 4.3 8.2 14.5 2.5 11.0 16.8 8.2 11.3 25.1 16.4 8.3 3.8 11.5 9.0 9.6 9.3 15.3 7.0 7.6 9.8 14.0 67.5 8.4 19.0 10.2 9.2 7.5 12.9 16.3 29.8 6.4 23.9 8.6 6.0 12.3 5.8 6.0 13.4 6.6 17.8 9.6 7.1 10.6 3.9 3.8 14.8 4.5 16.0 0.0 5.7 16.6 9.0 6.3 28.5 6.2 19.1 11.6 9.3 17.0 9.5 21.2 12.5 4.7 9.5 6.3 6.9 11.3 2.9 7.3 6.9 7.0 4.2 5.0 6.0 7.5 8.3 6.9 8.6 3.5 2.7 9.9 12.5 15.2 12.1 9.7 8.8 9.9 10.0 10.2 9.7 RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.6" "Lineage enriched" "Detected in many" 4 "dendritic cells: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB008649: AB_1619460, HPA023225: AB_1854144" "unprognostic (2.30e-1)" "unprognostic (7.05e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.47e-2)" "prognostic unfavourable (8.17e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (2.45e-1)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-3)" "unprognostic (1.98e-2)" "unprognostic (3.93e-3)" "unprognostic (5.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" 14.9 9.1 13.3 15.7 17.1 13.2 7.6 37.6 22.7 7.7 12.4 13.1 5.8 14.0 11.0 6.9 18.5 8.1 10.5 7.8 10.9 10.1 8.7 9.6 10.9 15.0 16.7 9.9 6.5 9.2 5.7 4.7 16.6 9.8 8.3 8.4 10.0 10.9 8.9 16.3 17.3 15.4 9.8 11.5 22.2 18.3 3.3 13.5 7.6 6.7 16.7 16.4 9.7 8.8 0.5 12.6 1.4 3.0 0.3 1.0 2.1 27.7 15.5 2.2 5.7 5.0 4.7 32.1 14.7 7.8 11.6 5.8 15.4 14.6 2.8 17.3 8.5 25.7 2.7 12.0 5.7 8.7 5.2 6.5 13.3 7.8 5.0 6.6 12.2 4.7 11.3 9.8 8.1 7.0 2.6 4.0 5.9 25.4 5.9 10.3 2.5 32.9 11.7 9.3 9.3 8.0 12.9 3.3 2.6 15.3 9.4 12.9 11.0 8.2 13.9 15.8 19.9 28.6 13.2 4.8 3.7 2.9 10.5 7.6 8.0 1.1 3.0 1.4 0.9 2.4 1.0 0.5 0.7 0.7 2.7 0.4 0.4 0.4 0.2 0.3 1.4 12.6 0.6 2.1 13.3 17.1 37.6 22.7 10.9 10.1 16.7 9.9 9.8 13.5 RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847862-91060636 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Enhanced Nucleoplasm Nucleoplasm "CAB025458: , HPA001274: AB_1079417, HPA001780: " "unprognostic (3.05e-2)" "unprognostic (2.19e-3)" "unprognostic (4.27e-4)" "unprognostic (1.98e-3)" "unprognostic (4.79e-2)" "unprognostic (4.20e-4)" "unprognostic (3.70e-2)" "unprognostic (5.80e-4)" "unprognostic (6.70e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-4)" "unprognostic (5.73e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" 4.9 2.4 8.3 13.0 21.6 5.8 16.3 32.9 12.2 7.0 11.0 12.0 4.2 9.3 11.8 2.6 11.9 8.9 6.7 6.1 9.0 7.9 4.5 4.1 6.1 7.3 12.8 9.7 10.2 4.9 12.0 6.9 14.9 11.0 8.0 11.7 2.8 8.7 9.9 14.3 6.6 9.8 19.4 17.1 7.4 9.8 5.2 13.7 4.8 8.6 7.8 7.7 11.6 7.3 5.8 2.5 20.0 3.2 8.4 7.1 2.2 1.2 1.7 2.0 1.3 0.0 0.4 8.5 0.7 1.1 2.2 3.4 0.9 2.2 5.8 2.4 2.1 3.7 1.7 1.7 4.7 0.9 3.1 5.8 1.6 0.2 0.0 5.7 29.5 0.5 3.5 1.4 1.1 2.4 0.6 6.6 2.3 2.4 1.7 2.9 0.6 2.6 3.1 9.4 2.9 2.5 2.2 9.9 3.1 2.4 14.8 8.4 2.8 1.9 0.5 0.7 1.3 0.6 2.9 2.9 2.7 5.0 1.4 4.2 9.3 10.5 2.7 7.8 3.6 2.1 5.9 4.4 4.8 3.5 2.5 5.8 5.6 3.0 20.0 8.4 3.2 1.0 7.1 2.2 8.3 21.6 32.9 12.2 9.0 7.9 12.8 9.7 11.0 13.7 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84187907 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 20.7" "Cell line enhanced" "Detected in many" "NTERA-2: 10.8;PC-3: 11.7;RH-30: 14.4;SH-SY5Y: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.7 2.9 5.9 1.0 12.2 0.0 2.3 4.7 5.1 3.1 4.5 1.1 20.7 1.7 2.7 4.0 1.5 4.0 1.9 1.2 5.1 2.9 9.2 0.9 0.8 0.2 1.5 3.3 4.9 3.4 13.5 9.1 0.5 4.4 4.3 3.7 1.5 3.0 15.0 1.4 2.3 2.0 1.7 1.0 0.6 2.4 2.6 2.7 0.8 14.5 0.9 0.6 3.3 2.3 1.2 0.8 2.4 0.5 0.7 2.8 0.1 0.0 3.6 3.5 0.0 3.4 3.4 0.0 7.5 4.0 3.4 2.8 2.7 3.0 0.0 0.0 4.1 0.1 9.0 6.0 7.9 0.0 4.5 0.0 0.1 0.0 3.0 0.0 0.0 1.9 0.0 0.0 3.7 0.8 0.0 0.1 2.7 0.0 1.3 0.1 10.8 11.7 0.0 14.4 0.0 0.5 8.3 0.0 11.5 0.0 4.2 0.0 1.9 0.0 0.0 0.1 4.3 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 2.4 0.4 0.5 0.5 0.3 0.4 1.2 0.4 0.7 0.8 0.6 0.4 0.4 1.1 0.7 0.5 0.4 2.8 0.1 5.9 12.2 4.7 5.1 5.1 2.9 1.5 3.3 4.4 2.7 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: " "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.6 10.4 8.9 8.4 6.1 9.0 6.7 9.9 9.2 8.7 9.7 8.5 5.3 12.9 12.3 8.2 5.5 11.7 8.9 14.0 7.1 13.1 8.8 6.8 9.7 9.1 13.6 8.9 9.1 6.8 10.1 7.5 11.3 11.7 8.3 6.4 74.4 16.1 5.8 6.0 8.0 9.5 15.0 12.1 7.2 7.9 6.5 7.8 8.3 4.8 5.2 9.5 7.5 9.7 8.5 14.1 6.9 13.1 15.0 12.7 14.5 6.4 8.4 6.7 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 RPS6KB2 "KLS, P70-BETA, p70S6Kb, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435408 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavourable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 8.7 14.1 8.5 12.8 9.2 18.0 11.2 12.9 11.5 13.1 13.0 12.5 12.3 19.8 10.2 10.1 36.1 11.0 10.7 10.7 8.8 4.2 11.3 27.8 10.7 12.0 11.4 8.7 9.5 18.7 9.6 11.7 13.8 8.7 17.2 9.9 11.7 18.1 15.8 25.0 41.4 17.7 8.8 7.6 18.6 17.1 7.5 8.8 21.8 11.4 28.6 21.8 10.1 15.6 15.7 27.1 16.4 28.3 17.8 20.7 20.2 21.7 16.5 9.0 15.2 4.2 8.1 11.8 10.5 13.2 19.7 13.7 25.7 14.6 8.0 18.3 10.3 16.2 10.1 16.0 8.0 13.8 27.0 12.9 21.0 20.9 14.2 16.3 16.0 10.3 16.9 10.4 10.7 14.6 20.7 21.5 9.9 33.3 25.1 25.7 9.7 21.2 18.6 12.5 38.0 9.1 12.5 13.6 14.6 10.8 30.1 22.4 35.4 13.6 6.1 10.3 11.0 24.8 11.7 19.3 15.8 12.9 16.9 10.3 12.8 9.7 22.6 16.4 15.7 25.2 15.9 15.7 14.9 15.3 27.1 14.3 10.9 11.9 15.1 17.8 28.3 18.7 20.7 20.2 8.5 9.2 12.9 11.5 8.8 4.2 11.4 8.7 8.7 8.8 RPS6KC1 humS6PKh1 ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274773 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Enhanced Endosomes,Lysosomes "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: " "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 12.0 14.1 15.6 10.0 19.4 6.4 17.1 13.5 19.4 14.1 13.1 12.6 8.8 9.2 15.9 8.4 10.3 11.8 11.6 9.4 17.3 15.6 9.8 10.8 13.6 7.5 17.8 16.8 14.4 13.5 19.9 16.7 12.3 15.3 17.6 10.1 7.3 8.9 17.7 14.1 6.7 8.7 18.5 22.3 11.0 12.5 26.5 13.2 6.8 10.4 6.1 7.8 14.6 16.0 2.5 8.7 13.7 6.8 4.0 3.3 2.2 7.4 6.4 10.6 11.4 10.6 15.7 9.3 9.8 14.4 15.2 17.5 5.2 8.3 4.7 6.6 14.7 6.1 12.8 8.0 11.6 9.9 4.7 12.7 7.6 7.2 9.8 8.0 15.1 10.3 6.9 13.3 7.3 12.6 16.3 7.3 15.5 4.0 3.3 2.6 15.3 7.3 4.0 10.0 4.6 7.0 7.5 6.2 16.1 10.6 8.4 14.0 12.0 3.4 11.7 10.4 9.6 11.9 6.4 4.3 8.3 3.6 4.4 3.1 10.6 13.7 4.6 3.3 2.8 6.8 2.3 2.5 2.3 2.4 8.7 1.9 1.5 3.3 0.5 4.0 6.3 1.0 1.6 2.2 15.6 19.4 13.5 19.0 17.3 15.6 17.8 16.8 15.3 13.2 RPS6KL1 MGC11287 ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903954-74923396 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell line enhanced" "Detected in many" "HMC-1: 12.8;SCLC-21H: 24.5;SK-BR-3: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.0;naive CD4 T-cell: 1.9;naive CD8 T-cell: 2.0;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 26 "B-cells: 2.0;dendritic cells: 5.4;T-cells: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794" Approved Approved Nucleoplasm Nucleoplasm "HPA027451: AB_10599304, HPA027794: AB_10602098" "unprognostic (2.71e-2)" "unprognostic (9.33e-3)" "unprognostic (3.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.44e-2)" "unprognostic (7.49e-4)" "unprognostic (2.06e-1)" "unprognostic (1.54e-1)" "unprognostic (4.09e-3)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.03e-2)" "unprognostic (7.52e-2)" 4.2 7.5 14.7 2.3 13.6 4.2 5.7 18.2 29.1 2.1 4.8 9.0 2.2 3.8 5.1 8.8 5.3 2.5 3.7 10.2 14.3 13.7 2.3 2.1 2.5 2.5 11.1 15.3 1.5 6.7 4.0 10.6 1.4 8.4 2.8 5.6 5.9 3.2 5.4 12.7 1.2 2.8 6.9 8.8 1.7 2.0 11.4 6.8 0.0 3.8 1.2 2.5 1.9 0.8 2.0 5.4 0.1 0.0 0.0 2.0 0.1 2.3 0.3 0.9 3.7 0.1 0.0 4.4 0.4 0.2 1.8 0.5 5.5 1.6 0.0 3.4 0.7 0.3 1.8 0.3 2.3 0.0 0.8 1.9 0.7 4.1 4.6 2.2 12.8 0.3 3.2 2.0 0.0 5.8 2.6 0.7 0.1 7.5 0.0 0.7 0.8 3.6 1.8 0.0 7.1 1.8 0.0 24.5 3.0 0.2 14.1 2.3 1.3 1.5 3.9 0.1 0.2 3.0 0.0 9.9 5.2 5.2 1.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.2 2.0 0.4 0.1 0.0 0.4 1.9 2.0 0.1 0.0 0.0 5.4 0.0 0.1 14.7 13.6 18.2 18.2 14.3 13.7 11.1 15.3 8.4 6.8 SAT1 "SAT, SSAT" ENSG00000130066 "Spermidine/spermine N1-acetyltransferase 1" P21673 X 23783173-23786226 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 71.3;hTERT-HME1: 109.8;RPTEC TERT1: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 206.1" "Group enriched" "Detected in all" 9 "granulocytes: 206.1;monocytes: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB047343, HPA055312, CAB069914" Supported "CAB047343: , CAB069914: AB_830224, HPA055312: " "unprognostic (4.19e-2)" "unprognostic (3.92e-2)" "unprognostic (6.41e-2)" "prognostic favourable (2.87e-4)" "unprognostic (8.58e-2)" "unprognostic (7.90e-3)" "unprognostic (8.52e-3)" "unprognostic (2.22e-2)" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (7.58e-2)" "unprognostic (5.13e-2)" "unprognostic (1.61e-1)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 93.5 40.5 34.2 73.0 60.5 177.2 57.2 14.2 38.9 49.2 56.5 24.6 143.2 82.2 43.9 51.9 56.9 36.8 80.6 81.5 53.7 27.7 79.2 116.1 163.6 67.3 31.9 22.2 26.5 32.3 19.3 74.4 185.7 100.2 51.0 49.9 39.3 110.6 173.3 14.4 25.4 65.5 23.5 100.8 108.6 64.5 25.6 27.1 23.0 102.7 41.1 60.6 52.4 29.6 7.3 19.0 206.1 136.4 1.8 13.2 34.6 7.8 15.9 4.0 6.3 34.5 14.1 11.0 11.5 19.4 2.8 6.7 7.5 23.2 13.1 21.2 2.7 11.9 2.1 71.3 10.5 4.3 9.7 6.3 6.9 63.5 44.4 6.1 6.1 29.2 54.5 22.3 109.8 23.6 2.6 11.6 8.3 7.4 4.4 27.6 2.7 7.3 3.8 2.6 15.6 91.3 16.2 1.1 1.1 11.8 26.9 22.7 4.1 1.3 8.8 23.5 1.1 14.0 5.6 4.9 1.1 2.9 14.0 3.6 4.4 25.8 42.0 26.9 4.1 110.5 2.6 7.3 4.9 3.3 19.0 4.7 2.9 3.3 206.1 1.8 136.4 9.4 13.2 34.6 34.2 60.5 14.2 38.9 53.7 27.7 31.9 22.2 100.2 27.1 SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced "HPA022136: AB_1856592, HPA057096: AB_2683334" "unprognostic (2.61e-2)" "unprognostic (1.27e-2)" "unprognostic (3.23e-2)" "prognostic favourable (8.76e-6)" "unprognostic (2.18e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "prognostic favourable (6.71e-4)" "unprognostic (4.14e-2)" "unprognostic (2.75e-1)" "prognostic favourable (6.05e-5)" "unprognostic (1.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" 11.3 43.9 14.8 6.3 16.7 6.4 11.0 11.3 17.4 12.5 33.4 9.2 10.8 51.5 11.7 14.9 8.9 10.2 11.3 14.5 13.4 9.8 49.6 73.2 9.1 8.9 18.3 17.1 19.9 20.0 11.3 13.7 5.5 15.2 11.5 9.2 13.9 16.2 13.6 12.0 7.9 47.9 10.1 10.5 12.5 13.3 11.7 16.8 2.7 18.5 11.9 7.3 9.9 13.3 8.6 18.4 5.5 25.6 6.6 11.8 12.9 7.5 11.6 10.1 19.2 15.0 18.6 1.3 5.3 18.4 11.6 15.1 3.7 3.9 1.5 3.0 5.0 6.7 6.3 5.1 7.5 2.2 19.3 1.6 6.2 19.2 19.5 0.0 5.5 24.3 12.3 6.8 4.7 17.0 1.0 2.4 12.3 0.6 0.1 1.6 4.0 8.0 2.9 5.0 1.8 17.4 8.6 1.1 10.0 5.2 10.2 9.6 6.4 1.6 8.3 5.5 4.0 0.1 7.7 5.0 4.2 0.2 19.9 2.2 8.5 4.6 25.6 5.5 8.9 17.1 10.5 8.6 7.7 9.1 18.4 8.3 11.8 8.4 1.6 6.6 8.8 8.3 11.2 12.9 14.8 16.7 11.3 17.4 13.4 9.8 18.3 17.1 15.2 16.8 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28292519-28323849 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 31.1;lymphoid tissue: 22.1;skeletal muscle: 39.6" "Cell line enhanced" "Detected in some" "AF22: 15.0;AN3-CA: 10.8;NTERA-2: 15.4;REH: 16.3;SCLC-21H: 23.8;SH-SY5Y: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.3;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.4;naive CD8 T-cell: 3.0;NK-cell: 1.4;T-reg: 1.4" "Group enriched" "Detected in many" 10 "NK-cells: 1.4;T-cells: 4.3" "Region enriched" "Detected in all" 5 "cerebellum: 306.7" "unprognostic (5.15e-2)" "prognostic favourable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.9 2.0 8.0 1.8 7.3 2.0 1.7 31.1 17.5 1.7 1.2 1.5 0.0 1.1 1.9 1.3 1.5 1.6 1.0 1.8 9.9 5.6 1.6 0.9 1.8 2.7 6.0 4.0 1.1 2.7 4.2 4.1 0.8 8.3 2.6 1.2 1.4 3.8 1.0 39.6 1.4 1.1 0.9 3.1 2.8 1.6 2.3 3.1 22.1 2.6 0.0 1.7 1.2 0.3 0.2 0.2 0.2 0.1 1.4 4.3 0.4 0.1 0.2 15.0 10.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.7 0.3 0.1 0.0 0.3 4.5 0.1 0.0 1.5 0.5 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 1.8 6.9 0.1 15.4 0.1 16.3 0.8 0.1 0.1 0.9 23.8 22.4 0.3 1.4 0.2 1.7 0.0 0.4 0.0 2.3 0.2 0.1 0.2 0.0 0.2 0.1 0.2 0.8 0.2 0.1 0.1 4.3 0.0 1.4 0.0 1.2 2.4 0.0 0.2 1.4 3.0 0.1 1.4 0.1 0.2 1.4 0.4 8.0 7.3 31.1 17.5 9.9 5.6 6.0 4.0 8.3 3.1 SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55529733-55537089 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "heart muscle: 45.7;tongue: 20.8" "Cell line enhanced" "Detected in some" "A549: 4.3;Hep G2: 3.1;MCF7: 4.4;NTERA-2: 8.7;RH-30: 8.1;U-2 OS: 4.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Enhanced "HPA030631: AB_10602088" "unprognostic (1.33e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-1)" "unprognostic (3.49e-1)" "unprognostic (5.43e-3)" "unprognostic (4.18e-3)" "unprognostic (2.08e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-1)" 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.7 20.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.4 1.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.3 4.4 0.0 0.0 8.7 0.0 0.0 8.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "heart muscle: 24.2" "Cell line enhanced" "Detected in some" "A549: 9.2;CACO-2: 3.2;CAPAN-2: 5.4;NTERA-2: 2.5;RH-30: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA078322 Approved Mitochondria Mitochondria "HPA078322: " "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.1 24.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.3 3.2 5.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 2.5 0.6 0.2 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927229-53051703 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Peroxisomes 370000 Peroxisomes "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favourable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favourable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" 29.1 26.2 21.8 19.9 21.2 14.0 30.3 12.0 19.7 24.4 51.9 15.9 28.1 49.2 19.0 28.8 32.2 18.1 32.1 29.3 20.0 20.0 54.2 168.3 21.8 14.0 25.6 17.8 22.8 24.6 16.7 24.1 17.1 21.9 25.5 40.5 18.9 21.8 23.3 22.0 18.8 80.1 20.6 27.1 20.9 33.9 16.7 19.4 23.0 28.2 28.6 17.6 22.3 20.5 36.4 57.1 67.8 50.7 40.8 49.2 61.2 25.9 14.3 19.3 35.3 63.3 54.1 20.9 31.0 46.6 20.4 29.6 12.8 28.2 24.7 33.6 45.4 18.3 13.2 29.0 31.2 36.0 19.2 26.6 20.5 26.3 42.2 38.3 44.9 43.9 39.6 24.2 12.1 57.7 23.6 12.9 41.2 15.0 42.5 33.3 21.1 28.1 22.4 33.9 33.8 56.5 44.2 16.0 19.2 27.1 55.0 25.9 28.1 43.8 44.6 27.8 14.4 48.4 24.7 21.6 27.4 28.9 36.0 38.1 25.7 55.4 48.7 67.8 49.2 50.7 39.9 36.4 39.2 48.6 57.1 29.8 33.2 47.1 7.5 40.8 46.8 37.1 47.1 61.2 21.8 21.2 12.0 19.7 20.0 20.0 25.6 17.8 21.9 19.4 SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395891 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" 5.5 8.8 10.3 7.0 20.6 13.3 10.8 21.4 22.5 7.1 10.7 14.1 5.0 15.3 5.8 7.6 15.7 5.0 5.6 6.1 14.7 11.3 10.6 28.6 6.7 6.9 9.7 9.4 5.9 11.3 27.2 11.7 8.5 14.9 8.5 11.5 9.2 9.5 6.2 10.1 22.5 22.1 5.2 15.6 6.3 9.1 5.8 11.0 8.0 9.4 9.4 9.1 7.1 9.9 5.4 3.0 0.6 2.5 2.1 5.0 1.0 19.2 11.9 9.9 9.9 6.2 5.0 15.1 9.4 4.3 4.8 4.9 25.1 12.4 22.5 11.6 4.4 15.9 15.2 8.3 7.0 6.2 7.2 14.2 8.6 14.7 5.9 18.8 4.7 3.9 7.5 10.5 10.5 4.3 16.0 7.8 6.3 8.4 11.2 9.4 12.7 8.2 10.2 23.3 11.4 9.3 14.9 21.7 9.2 8.0 17.0 7.5 8.1 5.6 7.0 8.2 10.6 10.7 14.5 10.7 26.5 30.8 8.4 11.7 7.3 0.1 1.7 0.0 2.2 2.5 2.3 5.4 2.3 2.9 1.7 2.6 3.0 5.0 0.6 2.1 2.1 3.0 4.1 1.0 10.3 20.6 21.4 22.4 14.7 11.3 9.7 9.4 14.9 11.0 SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317424-13348298 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm Nucleoplasm "HPA037645: AB_10671631, HPA062118: " "unprognostic (8.18e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (2.07e-1)" "unprognostic (3.50e-2)" "unprognostic (2.99e-2)" "prognostic unfavourable (2.16e-7)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.61e-2)" "prognostic favourable (3.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" 15.1 21.9 19.8 11.4 18.0 11.5 33.2 17.3 16.2 14.4 16.0 14.6 10.4 11.9 17.5 20.2 15.4 19.1 15.1 16.1 18.3 15.4 30.5 39.1 20.0 24.3 16.3 11.2 19.8 37.3 23.2 16.6 14.2 17.3 14.4 17.6 15.1 20.6 14.0 20.5 11.8 13.0 17.7 16.6 17.9 15.1 13.7 16.1 44.7 29.8 22.2 17.2 14.1 17.0 8.1 13.2 8.7 19.6 12.7 10.9 6.6 28.0 20.5 42.0 40.4 14.0 10.7 19.8 12.5 9.7 26.8 22.8 23.2 26.5 27.4 15.6 14.6 18.0 44.5 20.7 28.1 41.2 18.4 15.0 15.3 29.4 14.5 20.2 9.5 9.3 14.9 15.6 9.2 21.6 19.7 22.4 19.0 37.2 49.9 8.6 69.4 9.3 39.0 20.5 16.4 14.5 11.4 14.9 27.8 38.4 17.0 17.2 21.5 21.5 14.4 11.9 22.8 15.5 26.1 16.5 30.5 50.8 9.6 15.1 9.5 8.7 9.7 7.1 7.1 14.5 8.6 8.1 7.3 8.0 11.6 6.3 9.4 8.7 1.5 12.7 19.6 13.2 10.9 6.6 19.8 18.0 17.3 16.2 18.3 15.4 16.3 11.2 17.3 16.1 SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30446181 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.8;liver: 111.2" "Cell line enhanced" "Detected in all" "HMC-1: 94.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047931 Approved Approved Nucleoplasm Nucleoplasm "HPA047931: " "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" "unprognostic (1.92e-2)" "unprognostic (9.85e-2)" "unprognostic (2.67e-2)" "unprognostic (6.29e-2)" "unprognostic (5.67e-2)" "unprognostic (7.69e-3)" "unprognostic (2.38e-1)" "unprognostic (9.86e-2)" "unprognostic (9.66e-3)" "unprognostic (1.49e-1)" "prognostic favourable (4.35e-8)" "unprognostic (2.24e-2)" "unprognostic (1.35e-1)" "unprognostic (3.25e-2)" "unprognostic (3.62e-2)" 9.0 9.0 4.9 6.9 6.4 4.0 6.7 6.3 8.4 5.3 25.6 5.2 5.5 26.6 7.6 6.1 6.0 6.1 12.6 5.3 5.2 5.1 32.8 111.2 5.8 7.6 5.5 3.8 5.2 10.0 7.3 6.4 7.5 7.7 6.6 13.1 6.2 10.6 4.7 11.1 5.5 52.8 4.9 4.4 10.5 12.1 3.0 4.6 14.1 11.9 6.4 9.5 8.1 4.4 14.6 15.3 20.5 13.7 23.2 18.9 8.9 14.5 13.2 4.7 16.2 14.4 9.2 12.3 10.1 12.5 9.9 12.3 8.1 11.1 20.9 15.6 10.6 8.1 8.6 9.2 10.1 13.3 26.6 20.9 7.1 38.2 18.2 11.6 94.5 11.7 19.7 9.3 17.4 9.1 16.8 13.6 8.8 21.5 17.4 23.9 11.6 9.9 17.0 8.2 16.0 12.2 13.1 9.9 8.5 8.6 25.3 32.7 22.2 38.7 7.6 10.4 7.4 10.0 6.0 11.8 18.8 10.9 9.0 21.6 11.5 6.1 12.9 20.5 11.2 11.2 17.1 12.4 15.9 16.1 15.3 14.6 18.9 12.9 12.9 23.2 13.7 10.9 15.1 8.9 4.9 6.4 6.3 8.4 5.2 5.1 5.5 3.8 7.7 4.6 SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160442 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 34.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles Vesicles "HPA070409: " "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" 7.0 6.1 3.8 8.5 6.4 11.8 7.4 5.4 6.0 5.3 13.5 7.8 8.9 11.8 6.7 9.6 5.3 6.5 8.9 5.6 4.8 3.6 10.5 34.2 9.4 9.7 7.2 4.9 8.5 11.3 7.3 5.1 4.4 5.4 4.7 7.8 5.2 6.2 9.2 5.5 10.9 15.3 3.7 7.0 7.5 7.4 8.9 6.8 12.3 7.7 4.8 8.0 6.8 5.5 5.7 5.9 3.2 4.0 3.4 5.5 2.2 2.9 1.6 6.3 3.3 5.7 8.0 5.5 3.1 4.1 3.4 3.4 1.3 7.3 5.4 3.0 3.5 3.6 4.9 3.6 3.8 2.7 1.6 6.7 5.6 2.6 6.4 5.9 8.8 7.5 5.8 2.5 5.7 3.6 10.5 5.5 2.7 1.7 9.4 16.5 2.9 6.2 4.8 7.4 4.8 4.7 3.1 4.7 4.4 2.8 2.2 5.2 4.2 5.7 3.7 5.2 2.7 1.7 2.9 8.7 9.7 6.0 3.2 9.7 3.2 2.4 4.0 2.2 3.6 3.4 3.5 3.4 4.5 4.9 3.4 5.7 4.6 5.5 3.2 3.4 2.4 5.9 2.6 2.2 3.8 6.4 5.4 6.0 4.8 3.6 7.2 4.9 5.4 6.8 SETD1A "KIAA0339, KMT2F, Set1" ENSG00000099381 "SET domain containing 1A" O15047 16 30957294-30984664 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA020646: AB_1856752, HPA058376: AB_2683695" "unprognostic (8.62e-2)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.40e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" 11.0 10.5 10.0 12.4 10.2 25.6 10.3 23.0 14.5 11.1 12.1 14.1 7.6 10.2 15.3 6.7 9.4 11.2 9.7 7.6 8.8 6.7 9.3 10.5 9.0 12.6 9.3 9.8 15.3 14.8 15.6 12.9 11.3 9.5 10.9 5.7 13.5 12.7 10.5 15.2 12.3 11.4 11.7 8.0 14.5 10.3 22.3 10.0 15.5 12.7 5.4 14.1 10.6 9.9 2.0 2.6 2.5 1.4 1.3 1.6 0.9 6.4 12.5 8.6 10.0 4.9 3.5 9.3 7.3 5.5 6.3 5.3 10.6 6.6 17.3 8.1 6.7 8.5 7.7 7.4 5.2 9.2 30.0 8.0 21.6 11.8 4.7 13.6 13.8 5.9 5.9 8.8 5.6 4.8 16.1 9.8 3.4 13.5 16.1 13.8 12.2 8.3 24.5 8.5 10.9 3.9 7.1 9.3 9.5 9.8 8.1 5.4 8.4 11.0 6.5 9.5 9.2 6.0 7.6 14.9 18.0 16.9 7.6 11.8 7.2 0.0 0.8 2.5 1.2 1.4 1.6 0.2 1.0 0.8 0.6 2.0 0.7 1.5 0.5 1.3 0.4 2.6 0.4 0.9 10.0 10.2 23.0 14.5 8.8 6.7 9.3 9.8 9.5 10.0 SETD1B "KIAA1076, KMT2G, Set1B" ENSG00000139718 "SET domain containing 1B" Q9UPS6 12 121804180-121832584 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021667, HPA059412" Approved Enhanced Nucleoplasm Nucleoplasm "HPA021667: AB_1856753, HPA059412: " "unprognostic (1.69e-1)" "unprognostic (2.38e-2)" "unprognostic (6.32e-2)" "unprognostic (3.51e-1)" "unprognostic (2.06e-1)" "unprognostic (2.75e-2)" "unprognostic (5.32e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.75e-1)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 13.8 9.6 9.3 16.8 9.4 22.7 18.1 22.0 11.1 19.6 25.0 7.4 16.0 13.0 27.2 14.8 15.8 21.1 18.2 10.0 8.9 4.6 10.1 10.9 10.9 11.9 5.4 7.4 17.4 14.3 12.1 11.9 12.2 7.1 16.5 6.8 14.4 15.9 31.1 12.9 11.8 15.3 14.7 5.4 14.4 17.8 9.1 7.3 31.1 14.7 8.9 14.7 22.8 14.4 1.3 2.1 3.9 2.0 1.0 2.1 0.8 6.0 12.0 6.3 10.5 5.9 4.1 9.6 5.6 4.6 4.5 2.6 6.8 3.7 4.5 5.2 6.3 9.4 7.3 4.6 2.5 7.9 9.0 13.8 14.9 5.8 5.1 12.5 11.8 4.9 5.4 6.1 4.8 4.7 14.0 3.2 3.1 14.2 17.9 16.6 8.9 7.3 14.0 4.2 6.4 4.0 12.6 7.8 6.0 12.9 8.6 4.7 10.7 10.8 7.9 6.5 8.1 9.1 6.3 6.2 3.1 2.7 5.3 7.8 7.3 3.9 0.9 2.0 1.9 2.0 1.3 1.2 1.3 1.8 0.7 1.3 2.1 1.3 3.8 1.0 0.8 2.1 1.3 0.8 9.3 9.4 22.0 11.1 8.9 4.6 5.4 7.4 7.1 7.3 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2" Q9BYW2 3 47016429-47163967 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavourable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favourable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 13.2 10.5 12.2 15.2 15.4 20.0 11.7 22.4 16.4 13.4 14.0 9.1 12.9 9.5 15.8 7.5 10.8 11.4 8.7 8.8 10.6 6.8 11.4 10.3 10.4 11.8 11.7 9.5 16.0 13.4 21.4 16.3 10.7 11.3 12.4 10.9 7.7 12.7 14.8 27.6 12.5 11.5 11.9 9.8 13.8 10.4 12.8 12.8 23.2 15.8 5.5 12.8 16.1 15.5 4.8 2.6 6.0 2.3 7.1 3.9 1.0 11.4 9.0 15.2 7.8 9.1 10.6 6.4 10.6 10.3 12.4 11.3 9.5 7.5 25.3 6.6 14.5 7.0 16.4 10.1 16.8 14.5 6.5 25.9 15.1 7.3 6.8 19.4 15.0 9.1 9.7 12.2 15.2 11.4 16.6 9.6 10.1 6.0 14.2 2.6 11.5 7.5 9.4 14.7 13.1 6.2 15.1 6.6 10.5 17.8 7.0 6.6 7.4 14.4 14.6 13.6 10.2 11.6 16.8 12.2 13.6 25.5 7.9 11.1 7.9 2.4 2.2 5.2 3.9 2.3 2.4 3.7 2.4 3.0 2.5 4.8 3.5 3.0 6.0 7.1 1.9 2.6 1.0 1.0 12.2 15.4 22.4 16.4 10.6 6.8 11.7 9.5 11.3 12.8 SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3" Q86TU7 14 99397746-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria Mitochondria "HPA003591: AB_1079930, HPA003639: AB_1079931" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "prognostic unfavourable (6.46e-4)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (2.01e-1)" "unprognostic (4.42e-1)" "prognostic favourable (1.89e-15)" "unprognostic (6.81e-2)" "unprognostic (3.21e-1)" "unprognostic (2.20e-1)" "unprognostic (2.62e-3)" 17.1 12.5 24.7 13.3 26.8 9.2 16.6 14.6 23.8 14.3 22.7 18.7 26.9 16.2 14.2 39.6 16.9 21.7 13.4 34.1 24.1 17.9 43.4 21.0 16.7 11.9 23.7 13.9 11.7 16.9 17.4 14.5 19.4 18.4 16.9 17.6 16.2 24.9 20.2 68.7 14.1 16.5 26.0 25.3 13.7 15.4 39.1 15.3 11.5 25.6 20.3 10.9 24.0 21.4 9.2 18.6 19.9 17.4 16.0 18.2 11.3 13.7 15.9 12.0 11.4 14.0 15.8 42.7 17.5 13.4 18.4 18.8 15.3 23.5 13.6 14.4 19.7 18.0 14.6 19.7 29.4 13.3 7.8 12.3 10.3 13.9 17.5 18.5 18.6 11.0 25.9 16.3 23.9 22.8 9.7 20.5 20.2 25.9 19.2 20.1 7.1 18.1 11.7 24.6 11.1 26.3 17.1 21.5 10.0 15.7 16.4 13.4 22.2 16.1 20.1 8.3 11.5 55.8 13.3 14.7 16.6 14.6 15.6 18.4 12.6 6.4 15.0 19.9 15.5 17.4 18.2 9.2 13.4 14.5 18.6 7.6 11.2 13.9 9.4 16.0 14.8 11.7 9.7 11.3 24.7 26.8 14.6 23.8 24.1 17.9 23.7 13.9 18.4 15.3 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing lysine methyltransferase 7" Q8WTS6 4 139495941-139606699 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced Nucleoli Nucleoli "HPA058111: " "prognostic unfavourable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 26.1 13.2 12.0 9.6 12.3 5.7 26.3 10.2 16.2 27.9 17.7 17.9 11.0 4.8 23.8 12.0 18.3 13.8 16.9 25.2 13.0 10.0 7.2 30.7 12.1 6.9 18.0 10.1 13.3 13.8 26.8 9.3 12.0 15.4 22.8 10.2 12.4 13.7 13.9 56.4 14.2 9.9 33.3 19.0 11.8 17.7 10.6 16.5 2.9 10.3 15.2 9.9 24.2 30.1 2.3 6.8 1.8 5.6 0.5 5.6 1.6 8.9 11.5 4.4 2.6 26.1 22.5 9.7 21.2 22.0 10.8 9.2 6.8 12.2 20.8 8.4 35.6 4.5 14.6 16.7 17.7 10.2 10.3 2.9 15.0 0.2 12.9 9.9 4.4 19.5 19.6 17.2 18.4 13.7 1.7 32.3 13.8 14.9 6.5 1.5 2.1 7.6 6.1 15.3 11.9 10.5 8.2 17.2 5.7 14.1 20.9 5.0 8.3 9.1 22.2 19.2 13.6 22.9 17.5 28.0 26.8 13.2 22.1 10.0 9.2 1.0 5.6 0.5 0.6 3.2 4.1 1.8 1.8 1.8 6.8 2.3 0.8 0.5 1.8 0.5 4.8 3.5 5.6 1.6 12.0 12.3 10.2 16.2 13.0 10.0 18.0 10.1 15.4 16.5 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "U-698: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: " "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavourable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavourable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 16.9 15.4 9.5 21.2 15.9 16.9 17.7 21.6 18.2 18.6 15.4 25.2 18.6 13.0 22.8 18.9 15.6 16.8 14.0 10.9 9.6 8.5 13.3 12.7 15.6 20.7 15.3 13.2 23.9 17.6 21.0 15.4 18.4 13.7 14.9 16.8 20.6 16.1 18.5 20.0 18.0 17.1 17.9 13.7 21.9 15.0 33.5 14.2 24.5 18.6 12.0 20.7 18.6 16.3 11.2 12.8 6.9 14.9 7.6 9.1 5.3 5.7 6.7 9.8 6.4 4.7 6.3 16.3 4.8 5.5 6.9 5.9 4.5 8.0 11.4 6.6 5.3 7.3 9.1 5.1 5.5 5.5 11.3 6.4 6.9 5.2 6.7 11.3 6.1 8.2 5.8 5.7 9.2 8.1 10.8 9.3 4.9 11.1 7.8 6.6 13.4 5.4 9.1 6.3 8.4 5.3 6.6 7.1 13.0 7.3 8.6 5.8 9.3 15.4 5.4 4.0 4.2 4.4 6.7 9.7 10.4 88.6 4.2 4.0 3.9 6.8 10.7 6.9 8.3 14.9 8.7 8.7 7.4 9.1 12.8 11.2 8.3 8.3 6.5 7.6 10.6 8.6 4.7 5.3 9.5 15.9 21.6 18.2 9.6 8.5 15.3 13.2 13.7 14.2 SETDB2 "C13orf4, CLLD8, CLLL8, KMT1F" ENSG00000136169 "SET domain bifurcated 2" Q96T68 13 49444374-49495003 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012190, HPA071677" Approved Approved Nucleoplasm Nucleoplasm "CAB012190: AB_2186195, HPA071677: " "unprognostic (1.77e-1)" "unprognostic (1.11e-2)" "unprognostic (1.58e-1)" "unprognostic (3.61e-2)" "unprognostic (4.20e-1)" "unprognostic (3.70e-3)" "unprognostic (3.74e-2)" "unprognostic (3.44e-3)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.09e-3)" "unprognostic (7.95e-2)" "prognostic favourable (1.92e-7)" "unprognostic (2.83e-2)" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.85e-1)" 10.2 14.5 9.8 20.5 10.8 9.5 14.1 14.4 12.3 13.0 12.4 8.3 13.6 7.8 13.1 11.6 9.8 9.9 9.7 12.7 8.2 6.9 12.4 11.0 16.3 19.0 7.2 11.1 21.0 15.0 10.8 15.8 7.8 9.5 13.6 11.9 13.5 11.7 10.9 5.5 9.6 11.4 11.3 8.4 19.0 10.7 18.1 8.7 17.3 14.6 3.7 16.6 11.9 10.3 8.4 7.4 4.7 5.4 7.8 10.2 4.5 2.0 1.3 4.2 4.3 6.0 6.7 2.1 5.8 7.3 5.2 4.9 8.5 4.9 25.1 1.1 3.7 4.2 4.4 3.9 5.1 5.7 3.9 8.7 3.8 5.1 8.4 13.3 5.0 5.2 7.2 4.0 13.1 4.4 3.8 3.5 4.7 1.7 5.0 9.9 2.2 3.4 9.8 5.3 5.3 4.8 1.9 2.1 2.5 2.5 3.6 12.4 3.0 11.5 2.6 5.0 1.8 6.6 2.3 4.3 5.8 13.3 1.5 10.8 2.3 4.1 4.1 4.7 6.9 5.4 5.8 8.4 7.1 7.1 7.4 8.1 10.2 7.6 1.4 7.8 4.3 5.2 9.4 4.5 9.8 10.8 14.4 12.3 8.2 6.9 7.2 11.1 9.5 8.7 SETMAR metnase ENSG00000170364 "SET domain and mariner transposase fusion gene" Q53H47 3 4303304-4317567 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Methyltransferase, Multifunctional enzyme, Nuclease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA057999 Supported Nucleoli Nucleoli "HPA057999: " "unprognostic (1.59e-1)" "unprognostic (1.22e-2)" "unprognostic (5.24e-3)" "unprognostic (4.89e-2)" "unprognostic (7.73e-2)" "unprognostic (4.73e-2)" "prognostic unfavourable (2.85e-4)" "unprognostic (1.58e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-1)" "unprognostic (1.19e-3)" "unprognostic (1.19e-1)" "prognostic favourable (6.61e-6)" "unprognostic (5.42e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-3)" 14.1 6.2 7.3 7.2 9.2 3.7 14.2 6.9 8.5 12.5 6.5 6.2 5.2 4.3 19.4 7.6 7.2 12.5 8.2 6.3 6.6 4.3 10.1 5.3 5.1 6.5 9.1 8.7 19.4 9.8 5.7 7.4 5.6 6.5 13.9 6.9 5.7 11.9 10.0 7.7 7.3 5.7 16.8 7.2 5.0 6.0 7.3 10.8 13.1 11.5 8.3 4.4 11.3 13.3 3.8 1.6 1.9 3.3 0.5 5.3 1.5 2.9 2.7 8.1 1.7 19.4 6.5 8.2 3.3 1.0 3.2 3.1 2.8 2.3 7.9 3.5 1.8 2.6 7.1 5.0 3.6 5.3 6.1 9.8 4.8 4.5 2.2 4.6 4.2 7.6 3.8 2.4 0.8 4.7 6.5 3.0 5.0 4.1 6.9 2.9 7.9 4.6 8.1 8.0 3.2 3.0 4.1 6.4 9.5 4.0 5.0 4.2 4.7 2.7 3.1 4.9 6.8 4.1 4.3 3.9 9.4 19.5 1.7 5.3 4.0 1.9 1.1 1.3 2.3 3.3 2.0 2.9 2.7 2.9 1.0 3.8 4.5 5.3 0.2 0.5 1.9 1.6 1.7 1.5 7.3 9.2 6.9 8.5 6.6 4.3 9.1 8.7 6.5 10.8 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell line enhanced" "Detected in many" "HHSteC: 50.1;RPTEC TERT1: 76.9;SK-MEL-30: 49.8;TIME: 59.8;U-266/84: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: " "unprognostic (2.05e-2)" "prognostic favourable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.6 2.1 0.9 12.3 25.7 16.1 13.2 1.9 1.7 2.0 1.8 12.7 0.4 1.1 1.9 11.9 0.0 0.5 0.1 30.7 1.4 50.1 0.1 1.1 12.9 12.4 15.8 20.6 27.0 3.9 31.4 5.7 0.1 0.1 0.4 0.7 1.3 0.3 1.4 0.2 76.9 0.2 0.3 3.0 38.7 0.1 49.8 0.0 0.3 59.8 4.7 2.0 28.9 2.7 5.9 54.8 6.3 4.4 1.9 6.3 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 SGK2 ENSG00000101049 "SGK2, serine/threonine kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1;kidney: 39.1;liver: 32.9" "Group enriched" "Detected in some" 5 "A549: 13.5;CAPAN-2: 10.6;EFO-21: 5.4;Hep G2: 13.7;RPTEC TERT1: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm Nucleoplasm "HPA008859: , HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favourable (5.65e-4)" 11.4 0.7 2.8 4.3 9.9 0.2 3.1 1.0 10.2 1.4 21.3 33.1 0.9 17.8 1.0 19.7 0.7 1.6 7.9 0.7 4.3 2.5 39.1 32.9 0.6 0.5 6.9 5.1 3.2 14.1 0.5 1.7 0.5 13.7 1.4 23.4 0.0 0.9 1.8 0.4 3.2 20.7 1.0 14.2 0.7 11.9 1.0 6.0 0.0 1.0 0.2 0.2 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 10.6 0.0 5.4 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 13.7 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 19.4 2.2 0.1 0.5 0.0 0.9 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 9.9 1.0 10.2 4.3 2.5 6.9 5.1 13.7 6.0 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66667596-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Supported Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favourable (5.52e-6)" "prognostic favourable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favourable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 6.5 5.9 13.9 8.7 20.9 7.7 23.9 9.8 14.8 12.0 10.0 24.0 8.7 8.6 8.0 10.3 7.6 7.8 7.8 5.4 16.1 10.2 14.9 13.6 9.9 8.5 28.8 9.3 9.8 15.6 29.2 14.8 5.9 14.6 7.8 10.7 17.2 7.0 7.7 6.1 12.4 10.8 6.0 32.8 8.2 7.2 8.9 21.9 8.3 17.3 4.3 6.8 6.1 8.0 5.8 13.8 21.4 15.7 6.9 13.3 8.0 11.4 2.9 0.5 1.8 3.5 6.8 6.5 7.3 6.9 4.0 4.2 5.2 7.7 8.6 1.8 8.0 3.7 6.0 4.3 5.0 4.8 10.2 7.8 2.1 5.1 3.5 7.0 9.3 3.3 3.8 1.9 6.7 6.4 1.5 4.2 7.6 1.8 5.5 4.3 1.6 4.0 9.7 4.3 5.8 5.4 2.6 2.5 1.9 3.3 4.9 11.0 23.1 14.0 7.6 3.8 3.4 3.3 2.7 5.2 9.9 9.9 4.4 11.8 3.9 21.4 15.7 6.2 8.1 9.3 13.3 3.7 8.4 8.5 13.8 5.8 9.0 6.9 2.5 6.9 4.4 7.7 5.3 8.0 13.9 20.9 9.8 14.8 16.1 10.2 28.8 9.3 14.6 21.9 SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "pons and medulla: 17.0" "Group enriched" "Detected in some" 8 "classical monocyte: 5.7;eosinophil: 3.9;intermediate monocyte: 2.4;myeloid DC: 6.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 32 "dendritic cells: 6.6;granulocytes: 3.9;monocytes: 5.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA015076 Supported "HPA015076: AB_1857298" "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favourable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" 7.5 3.3 1.9 8.6 2.9 2.1 8.0 1.7 1.9 8.3 22.2 3.4 5.6 11.4 12.5 9.7 14.9 7.5 24.9 7.8 2.5 2.6 13.2 12.6 20.7 6.4 2.7 1.4 5.4 8.4 4.6 48.5 30.7 17.0 8.0 6.4 11.8 14.2 3.2 5.0 4.5 38.1 18.5 4.6 1.5 9.8 8.6 1.0 0.2 22.0 12.2 5.3 10.7 11.2 0.1 6.6 3.9 5.7 0.0 0.1 1.4 9.9 3.8 0.5 2.9 6.6 15.4 0.2 12.3 9.3 5.8 6.1 1.7 20.7 0.7 4.9 19.4 3.7 7.1 10.8 10.4 2.8 2.8 0.4 8.4 0.5 7.6 6.7 0.0 5.3 7.6 11.3 13.8 12.8 0.1 0.2 9.2 3.3 0.2 0.0 0.3 4.2 0.2 5.0 1.4 15.5 4.9 1.0 0.0 9.3 13.4 1.6 7.2 0.1 21.8 7.0 11.1 10.0 5.6 0.7 0.2 0.4 9.4 1.6 2.9 0.0 5.7 3.9 0.0 2.4 0.0 0.1 0.0 0.0 6.6 0.1 0.1 0.0 0.5 0.0 2.0 0.0 0.0 1.4 1.9 2.9 1.7 1.9 2.5 2.6 2.7 1.4 17.0 1.0 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094256-169271105 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.9;myeloid DC: 3.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;monocytes: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074783 Approved Supported "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA074783: " "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favourable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 15.2 4.8 13.8 7.2 11.8 3.7 11.1 2.5 12.7 7.5 17.2 15.9 10.8 15.7 6.8 7.2 7.1 6.9 19.7 7.8 17.8 9.3 14.6 9.6 11.3 3.7 13.0 10.9 11.9 12.0 5.2 7.8 8.6 10.3 17.2 16.0 10.7 20.9 10.7 16.2 6.8 17.2 8.8 11.7 4.5 27.6 7.0 11.3 0.9 23.1 7.6 5.5 9.4 6.3 0.4 3.4 0.0 8.5 0.3 0.0 0.7 7.3 6.2 5.6 16.2 6.1 7.6 7.3 20.6 10.0 15.4 7.1 6.1 8.9 0.0 1.0 21.4 4.9 4.5 8.1 17.0 0.0 2.6 4.3 14.1 3.2 13.8 1.5 0.1 4.5 4.5 13.1 10.4 9.4 0.0 0.0 14.2 3.0 1.5 1.4 2.8 5.3 2.3 1.8 0.3 7.0 5.8 4.2 5.1 5.2 8.0 2.0 2.6 0.6 8.5 7.3 5.7 12.1 7.2 0.5 0.0 0.0 8.2 1.5 8.7 0.0 1.4 0.0 0.0 5.9 0.0 0.4 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.3 8.5 0.2 0.0 0.7 13.8 11.8 2.5 12.7 17.8 9.3 13.0 10.9 10.3 11.3 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936579-146081791 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 40.8" "Cell line enhanced" "Detected in some" "A-431: 10.5;CACO-2: 35.8;HBEC3-KT: 11.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basal ganglia: 11.5;cerebral cortex: 2.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.4;T-cells: 1.6" "Region enriched" "Detected in single" 14 "basal ganglia: 23.9" "Region enhanced" "Detected in many" "basal ganglia: 14.5" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA035903: AB_10696515, HPA058119: " "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 2.6 0.6 1.2 6.2 11.5 0.0 2.9 0.2 2.9 6.4 19.1 0.4 0.4 9.2 2.9 2.2 22.2 3.6 40.8 23.5 0.8 0.3 0.8 4.6 1.9 0.0 0.3 1.1 1.0 14.3 0.0 3.3 0.3 0.1 2.2 8.5 0.9 16.9 1.0 21.7 33.1 21.4 1.2 0.5 0.2 11.9 6.4 0.6 0.6 3.8 19.6 16.1 0.9 10.0 0.0 1.4 0.3 0.1 0.0 1.6 0.3 10.5 2.9 0.1 0.6 0.0 0.0 0.0 0.1 0.8 2.2 0.9 35.8 9.9 0.0 5.6 0.4 9.8 0.0 11.5 2.1 0.1 0.1 0.0 4.2 4.8 0.6 0.0 0.0 0.1 6.2 3.3 7.9 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.8 0.0 0.1 0.0 4.6 1.0 0.0 0.0 0.6 0.2 0.2 3.4 0.0 5.0 0.4 9.2 0.8 3.4 0.0 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.0 1.2 0.0 0.0 0.0 1.6 0.7 1.4 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.8 0.3 1.2 11.5 0.2 2.9 0.8 0.3 0.3 1.1 0.1 0.6 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 57.8;liver: 108.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023314 Enhanced Supported Nucleoplasm,Cytosol 240000 "Nucleoplasm, Cytosol" "HPA023314: AB_1856830" "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favourable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favourable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 10.9 3.2 2.2 4.9 4.1 2.1 10.4 6.5 3.0 4.6 15.2 5.3 7.3 12.3 2.8 7.4 16.3 3.9 4.0 2.0 2.6 1.8 57.8 108.3 4.3 3.8 3.5 1.9 4.1 3.5 30.1 1.6 2.8 3.6 3.4 3.5 7.2 9.8 8.0 5.7 6.2 15.1 2.3 2.9 8.6 3.9 6.3 3.8 11.1 10.9 10.8 8.7 4.3 6.3 8.6 6.7 6.2 10.6 13.0 18.7 7.9 23.7 24.1 7.6 12.0 19.5 12.2 28.3 5.0 6.2 16.9 18.7 23.9 10.6 18.5 15.0 4.3 23.5 16.0 20.2 9.6 11.0 23.3 8.3 18.9 18.0 4.9 5.5 9.0 10.1 8.0 13.1 5.9 11.6 7.0 4.2 6.0 17.5 27.4 7.6 9.6 7.9 22.5 30.3 15.7 26.9 16.2 10.5 5.5 34.2 6.5 8.6 26.6 7.8 2.7 3.3 9.8 29.9 15.8 8.6 8.2 7.4 6.4 13.0 7.8 6.0 8.2 6.2 10.1 10.6 17.1 8.6 12.3 12.8 6.7 6.9 12.3 13.0 0.1 13.0 7.5 3.1 18.7 7.9 2.2 4.1 6.5 3.0 2.6 1.8 3.5 1.9 3.6 3.8 SHMT2 SHMT ENSG00000182199 "Serine hydroxymethyltransferase 2" P34897 12 57229327-57234935 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.1" "Cell line enhanced" "Detected in all" "RH-30: 208.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020543, HPA020549" Enhanced Enhanced Microtubules,Mitochondria 160000 Mitochondria Microtubules "HPA020543: AB_1856833, HPA020549: AB_1856834" "prognostic unfavourable (8.37e-5)" "unprognostic (1.24e-1)" "unprognostic (1.90e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (4.97e-2)" "unprognostic (1.58e-2)" "unprognostic (9.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "prognostic unfavourable (4.84e-8)" "unprognostic (3.05e-1)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (4.74e-2)" 13.0 13.5 5.9 15.0 7.1 12.6 9.5 9.6 9.5 10.5 11.5 6.1 5.0 13.4 10.2 8.5 22.1 8.6 10.3 11.0 6.5 5.4 15.5 103.1 11.8 18.7 8.7 4.6 17.9 38.9 4.5 8.1 16.8 6.5 10.3 9.4 7.1 44.6 5.7 16.5 13.7 11.5 9.9 7.6 23.5 13.4 5.4 6.3 26.1 13.2 19.0 25.6 11.2 13.8 33.6 14.5 6.5 11.7 9.7 48.7 12.3 24.6 11.4 11.6 30.6 9.1 14.0 23.0 13.4 21.8 17.9 16.5 16.4 11.9 45.7 22.2 16.5 15.8 20.9 21.7 9.7 25.5 18.6 18.8 7.0 11.6 67.4 31.1 16.7 17.9 31.6 14.4 48.2 17.8 19.7 43.5 13.6 16.2 24.7 17.0 9.9 18.6 16.7 208.3 42.3 9.0 11.4 24.9 11.9 7.0 16.5 48.4 22.4 38.3 11.2 7.3 14.8 9.4 18.1 58.3 31.9 38.8 15.7 29.0 13.0 6.5 9.8 5.9 6.9 11.7 8.0 33.6 12.1 7.4 14.5 32.4 5.3 5.4 0.5 9.7 7.5 4.8 48.7 12.3 5.9 7.1 9.6 9.5 6.5 5.4 8.7 4.6 6.5 6.3 SHPK "CARKL, SHK" ENSG00000197417 Sedoheptulokinase Q9UHJ6 17 3608262-3636322 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA024361, HPA064939" Enhanced Approved "Nucleoplasm,Nuclear speckles" 150000 "Nucleoplasm, Nuclear speckles" "HPA024361: AB_1846030, HPA064939: " "unprognostic (1.75e-2)" "unprognostic (1.51e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (3.57e-3)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-2)" "unprognostic (1.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.08e-2)" "unprognostic (1.42e-1)" "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" 8.9 12.9 7.6 6.2 10.6 5.9 8.9 17.3 12.3 8.8 14.1 14.9 8.8 18.5 10.7 6.1 11.6 7.6 5.3 5.9 7.0 5.5 14.3 26.7 6.3 5.3 12.0 4.5 10.2 13.7 11.8 6.2 8.6 9.8 7.4 8.6 12.3 8.9 9.4 7.5 12.1 22.8 5.1 6.7 6.1 9.7 5.2 13.0 7.7 7.7 4.0 7.6 7.5 9.6 5.2 7.1 5.1 4.8 6.4 7.5 5.4 5.2 10.7 11.5 7.3 4.8 4.8 6.4 3.5 3.2 6.9 4.2 18.5 4.9 6.2 7.9 6.8 10.3 15.2 11.5 5.1 10.0 14.8 6.8 9.2 13.2 5.7 5.9 9.7 8.1 5.5 7.6 5.2 13.0 9.0 8.0 6.7 9.4 7.5 4.6 5.8 7.2 10.4 6.0 9.9 9.8 6.8 3.3 8.8 12.9 12.0 3.6 10.7 3.5 9.3 10.6 5.1 10.2 8.5 2.7 3.4 4.1 11.5 5.3 5.4 3.3 4.7 5.1 4.6 4.8 4.7 5.2 4.2 3.7 6.5 4.0 7.5 4.7 0.9 6.4 4.1 7.1 3.6 5.4 7.6 10.6 17.3 12.3 7.0 5.5 12.0 4.5 9.8 13.0 SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA034950" Approved Approved Mitochondria Mitochondria "HPA034854: AB_10964488, HPA034950: " "unprognostic (3.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.61e-3)" "unprognostic (1.53e-2)" "unprognostic (7.40e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (5.03e-1)" "unprognostic (7.90e-2)" "unprognostic (6.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" 10.9 7.3 8.3 11.0 10.0 5.5 10.4 38.0 11.5 10.6 8.0 4.5 10.8 6.0 14.1 9.2 8.5 9.8 6.7 7.2 7.2 4.2 8.4 6.5 7.1 9.0 7.6 5.9 18.8 8.7 11.4 19.7 6.6 8.5 8.3 7.4 7.3 10.2 13.7 11.4 13.9 8.2 11.0 10.3 8.8 8.5 10.7 8.7 8.4 12.5 7.2 8.0 10.7 11.5 6.7 4.8 4.4 2.4 3.4 4.3 1.2 2.9 2.3 11.4 6.7 5.3 5.7 5.5 3.5 2.9 4.4 5.7 5.2 2.1 10.4 4.4 2.7 5.1 7.0 5.0 5.8 4.7 8.0 10.5 5.2 4.4 4.0 22.0 6.5 3.9 5.8 4.1 6.0 4.7 14.6 5.9 3.7 2.6 14.1 8.2 7.7 4.0 10.2 17.8 3.5 6.0 2.9 9.4 6.6 6.3 5.8 3.9 3.1 10.6 5.2 2.8 5.3 5.5 4.1 4.8 6.8 12.4 2.9 9.5 4.3 1.6 2.3 4.4 4.3 2.4 3.7 3.9 3.6 2.9 2.7 6.7 4.1 3.3 0.1 3.4 2.4 4.8 3.3 1.2 8.3 10.0 38.0 11.5 7.2 4.2 7.6 5.9 8.5 8.7 SIAH1 hSIAH1 ENSG00000196470 "Siah E3 ubiquitin protein ligase 1" Q8IUQ4 16 48356364-48448402 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 102.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018724 Enhanced Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB018724: AB_2188865" "unprognostic (7.08e-2)" "unprognostic (1.16e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-3)" "unprognostic (1.25e-2)" "unprognostic (7.93e-3)" "unprognostic (1.12e-2)" "unprognostic (9.22e-3)" "unprognostic (3.26e-1)" "unprognostic (8.02e-2)" "unprognostic (7.84e-3)" "unprognostic (7.67e-3)" "unprognostic (4.38e-2)" "unprognostic (4.00e-1)" "unprognostic (9.55e-2)" "unprognostic (1.26e-2)" 20.6 11.4 11.9 11.0 13.5 19.2 25.5 15.5 16.6 14.6 13.1 15.0 6.5 12.8 16.8 13.4 12.7 12.9 12.9 11.4 12.6 11.6 12.1 17.5 13.9 10.0 12.8 11.6 16.7 11.4 13.1 9.1 102.6 14.1 14.2 12.2 32.1 13.2 12.1 17.0 16.6 16.0 18.6 12.7 11.3 12.5 17.9 13.0 17.5 14.5 9.3 11.5 15.9 14.8 12.6 8.3 21.9 5.2 5.3 6.1 3.5 8.4 7.6 16.6 14.9 14.3 12.5 17.0 7.9 10.8 11.8 5.8 5.8 11.1 11.0 8.8 10.0 9.9 11.4 11.6 14.6 4.4 9.2 5.9 6.0 15.1 20.0 5.8 9.1 15.0 20.9 6.9 16.1 9.9 9.5 10.5 9.6 5.8 15.6 11.9 20.2 11.8 18.2 25.0 11.6 11.0 10.7 18.9 16.8 23.6 11.8 20.3 7.5 13.4 10.5 12.7 11.4 6.8 8.4 13.7 5.7 20.2 9.4 7.2 11.4 6.9 5.2 21.9 2.7 2.2 3.0 12.6 3.0 4.2 8.3 12.1 6.1 4.5 2.9 5.3 1.3 7.9 1.6 3.5 11.9 13.5 15.5 16.6 12.6 11.6 12.8 11.6 14.1 13.0 SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741127-150763477 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: " "prognostic favourable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavourable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" 9.6 48.0 7.6 11.8 10.3 22.7 23.5 10.9 17.2 30.0 10.5 8.4 20.3 7.9 23.5 13.9 28.8 14.9 11.0 10.7 7.2 7.3 8.4 35.5 11.8 19.1 9.9 7.5 19.0 14.6 6.4 8.1 31.4 7.9 18.8 9.2 8.3 11.2 21.7 8.3 19.3 9.5 17.4 9.4 16.9 12.0 8.7 8.6 23.6 11.4 10.6 25.1 22.7 25.6 3.0 3.1 10.0 2.7 1.6 3.6 1.1 16.6 4.1 3.2 6.4 11.1 8.4 13.1 6.9 8.0 8.4 10.3 8.4 7.5 9.3 10.2 7.2 10.3 8.7 6.2 7.9 7.8 6.2 18.2 5.0 27.9 15.9 10.0 5.4 7.6 14.5 5.0 11.5 6.5 4.5 36.7 5.3 20.0 18.3 5.1 10.5 8.2 13.5 7.0 33.3 5.3 5.8 12.5 5.9 5.2 4.9 12.3 32.9 15.1 4.5 5.8 5.2 12.6 9.3 43.7 16.6 13.0 5.5 14.5 2.9 9.5 2.7 10.0 2.1 1.5 3.2 2.5 3.6 3.2 2.4 3.0 1.9 1.9 5.9 1.6 1.5 3.1 2.0 1.1 7.6 10.3 10.9 17.2 7.2 7.3 9.9 7.5 7.9 8.6 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427189 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 34.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 16.7;HeLa: 27.8;hTCEpi: 21.5;LHCN-M2: 21.6;U-266/84: 15.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "B-cells: 2.0;dendritic cells: 1.6" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB023801: , HPA038211: , HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 8.8 2.3 3.0 3.6 3.0 5.9 7.5 3.0 3.0 13.5 3.0 3.0 3.0 0.0 3.0 3.0 12.9 5.5 10.7 7.1 3.0 0.8 3.0 12.3 5.4 3.0 3.0 3.0 13.7 7.3 3.5 5.7 8.2 3.0 3.9 0.1 3.0 4.6 9.8 5.0 34.5 3.0 3.3 3.0 4.0 5.3 3.0 3.0 3.0 3.9 3.0 3.0 10.5 6.1 2.0 1.6 0.0 0.1 0.0 0.1 0.1 0.5 1.7 2.0 0.0 0.1 0.8 0.7 0.9 0.3 1.6 1.3 2.4 0.0 2.4 0.7 0.2 11.1 1.6 16.7 1.0 0.1 0.5 0.7 27.8 0.9 2.3 0.7 0.1 1.0 21.5 0.4 5.1 0.3 0.1 0.5 21.6 0.1 0.4 1.7 0.8 1.5 0.0 0.3 2.5 1.9 6.3 0.0 0.0 10.9 1.8 0.4 1.1 0.3 3.7 0.4 2.0 0.1 0.0 4.3 15.7 0.4 4.6 2.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 2.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 3.0 3.0 3.0 3.0 3.0 0.8 3.0 3.0 3.0 3.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016026 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA016026: AB_1857321" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favourable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favourable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.8 3.9 6.8 7.3 34.0 10.1 4.0 5.1 7.3 3.9 4.5 13.1 6.2 4.6 7.1 5.9 8.3 5.3 3.8 5.1 3.4 2.2 5.0 3.4 6.4 7.4 4.8 3.3 9.8 5.7 5.7 7.4 4.6 4.6 6.7 6.1 2.7 5.0 4.4 2.3 3.9 6.7 7.3 5.5 8.7 5.3 3.2 7.5 7.5 3.1 3.0 7.5 3.9 6.4 8.6 5.2 5.5 7.0 1.9 1.5 9.7 2.8 6.8 5.8 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967201-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" 17000 "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favourable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 15.2 11.2 13.7 11.0 36.7 14.6 16.1 16.7 13.1 16.6 19.0 9.9 10.9 9.1 17.0 12.1 40.2 12.1 13.6 17.2 10.6 7.1 14.9 12.2 17.1 10.1 11.2 13.4 17.2 12.5 22.6 13.1 17.4 12.8 19.3 13.6 11.4 19.8 12.7 19.3 16.6 15.5 29.8 13.0 12.1 15.7 10.2 12.8 12.0 15.8 21.6 12.5 24.9 23.6 1.4 2.2 6.5 1.4 1.3 3.6 0.7 21.2 12.4 14.9 10.6 16.1 22.5 6.3 13.3 17.7 9.9 9.3 7.9 22.9 11.3 8.3 13.7 23.2 7.8 16.8 14.5 9.0 10.8 11.5 10.2 6.6 12.1 13.7 10.0 11.5 22.1 13.4 39.2 17.8 14.3 7.8 13.0 7.4 9.6 7.6 3.7 8.0 9.4 18.3 5.8 13.0 24.5 3.5 6.1 11.5 11.2 11.0 5.8 9.9 26.9 7.3 7.6 13.4 15.5 9.5 11.6 7.2 10.8 18.4 4.7 1.2 1.4 3.3 3.6 1.2 3.6 1.1 2.2 2.2 1.2 1.4 1.5 2.5 6.5 1.3 1.0 2.2 1.4 0.7 13.7 36.7 16.7 13.1 10.6 7.1 11.2 13.4 12.8 12.8 SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1, nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804853-18926454 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported Nucleoplasm Nucleoplasm "HPA006870: AB_1079725, HPA031623: , HPA073972: " "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (5.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (8.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" 4.7 3.0 2.1 4.5 3.5 11.7 6.2 13.2 3.0 4.4 4.5 3.1 5.4 5.1 5.5 4.0 3.0 4.5 2.3 2.2 4.6 5.4 4.1 6.2 2.3 6.3 4.5 7.2 3.9 3.1 4.2 5.0 4.7 3.3 21.1 14.4 5.0 3.9 3.4 4.5 4.3 4.0 6.0 5.8 5.2 4.9 7.1 4.6 19.1 5.6 2.3 6.1 1.0 23.2 15.6 14.7 10.4 16.9 17.9 10.9 10.9 10.7 11.9 13.3 13.7 8.6 32.1 15.7 15.1 13.3 16.9 9.5 19.0 20.6 10.6 14.6 13.7 17.5 13.7 19.6 11.6 10.5 16.1 24.5 29.6 16.6 22.4 17.9 13.1 12.4 13.5 11.8 15.7 9.0 15.7 19.8 11.0 10.2 18.3 13.4 10.2 16.9 11.5 11.9 9.2 12.5 21.0 17.9 12.0 11.0 16.1 9.2 11.9 21.2 11.9 15.3 10.6 19.1 2.5 3.4 6.1 2.8 2.9 3.7 4.0 4.3 2.5 7.1 5.4 4.7 7.6 2.3 5.6 4.6 3.7 1.0 SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940573-21994835 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" 26000 "Nuclear bodies" Cytosol "HPA029849: AB_10602072, HPA029852: AB_10611521" "unprognostic (2.51e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (7.49e-4)" "prognostic unfavourable (7.79e-8)" "unprognostic (1.02e-2)" "unprognostic (2.72e-1)" "unprognostic (3.18e-3)" "unprognostic (3.95e-3)" "unprognostic (2.45e-1)" "prognostic unfavourable (7.85e-5)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (8.50e-2)" 21.7 48.1 29.7 18.7 25.0 18.6 28.4 36.6 35.4 20.8 23.1 8.1 26.0 23.5 20.8 31.3 19.2 13.3 20.9 26.3 22.3 25.0 55.1 19.5 17.6 18.5 25.6 28.5 42.4 16.7 13.6 19.2 63.6 24.2 61.3 24.4 15.7 20.7 20.6 18.0 9.7 25.1 36.8 17.4 18.9 18.8 18.4 11.0 19.6 27.6 11.7 20.8 28.2 16.5 13.2 19.4 37.0 25.7 11.7 20.3 12.3 90.6 23.2 39.6 15.0 10.5 17.8 12.3 24.9 14.9 38.3 36.7 28.8 29.7 32.9 8.6 25.4 19.9 38.7 45.4 75.8 15.2 18.1 17.0 28.0 20.4 19.3 32.9 15.0 11.7 13.9 39.3 73.9 36.6 36.2 4.6 52.1 19.3 24.3 33.0 67.1 34.5 24.3 27.2 25.0 51.0 12.9 18.9 15.3 19.9 25.6 65.5 23.1 13.7 32.3 27.8 28.0 57.6 40.4 3.5 7.0 19.6 54.2 14.7 38.5 2.9 21.4 37.0 7.6 22.1 9.4 13.2 12.0 13.2 19.4 8.3 7.9 9.3 21.1 11.7 25.7 4.0 20.3 12.3 29.7 25.0 36.6 35.4 22.3 25.0 25.6 28.5 24.2 11.0 SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027438-99144100 "Enzymes, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Uncertain Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA019671: , HPA055245: " "unprognostic (2.21e-1)" "unprognostic (6.15e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.81e-1)" "unprognostic (4.62e-2)" 15.0 11.1 8.7 10.5 15.0 23.8 12.4 12.1 16.5 11.8 10.9 20.9 6.9 9.5 11.6 5.7 19.3 10.2 12.5 7.9 9.3 8.4 10.3 10.1 16.0 8.1 15.4 9.4 19.6 22.5 9.0 15.1 15.4 14.9 11.7 10.6 14.3 13.4 9.6 10.7 17.3 10.3 9.8 10.6 9.1 19.5 26.0 11.8 6.6 7.8 6.6 12.7 11.5 13.3 1.2 1.2 2.4 1.9 1.0 2.1 0.6 13.8 7.9 6.4 4.6 5.1 5.4 9.6 7.8 7.5 6.3 5.9 4.0 11.5 4.3 8.4 7.2 7.6 3.6 10.0 6.6 3.3 3.0 2.3 4.6 3.8 4.8 2.6 5.7 4.9 7.0 9.9 11.5 6.0 7.0 7.7 5.8 11.2 4.5 5.5 7.5 8.5 4.3 6.0 2.6 6.9 11.4 2.8 6.4 7.4 9.8 6.8 3.1 5.0 8.7 10.0 10.3 17.9 15.4 6.9 4.7 4.6 5.0 5.2 15.5 2.0 1.4 2.3 1.3 1.5 1.6 0.9 2.1 1.3 1.1 1.2 1.2 1.0 2.4 1.0 1.9 1.2 2.0 0.6 8.7 15.0 12.1 16.5 9.3 8.4 15.4 9.4 14.9 11.8 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542295-64662068 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 54.0;HBF TERT88: 41.5;LHCN-M2: 41.5;TIME: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA071508: " "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 12.3 9.2 10.5 9.0 15.0 11.5 10.2 16.7 10.0 9.2 9.1 11.5 8.1 9.3 7.9 6.9 7.6 7.8 10.5 8.2 12.6 4.6 9.4 5.7 19.0 8.6 9.5 4.8 8.5 9.0 8.2 10.7 15.3 10.1 10.6 8.2 9.6 9.9 7.6 7.5 11.0 13.7 8.9 6.6 9.9 9.8 21.6 10.6 8.9 11.4 4.1 9.6 9.4 11.7 3.0 3.0 4.8 2.2 7.3 3.5 1.7 15.6 4.3 3.7 2.8 2.6 10.0 1.8 54.0 24.6 21.1 18.4 2.4 12.0 2.1 3.4 9.2 3.5 3.5 9.3 41.5 1.1 2.3 2.2 2.6 2.9 2.3 2.9 1.4 2.7 3.6 29.3 11.2 24.3 3.2 2.1 41.5 3.4 6.7 1.3 2.2 5.7 1.5 9.0 1.3 5.8 2.8 3.5 3.1 3.3 1.7 2.5 2.8 2.3 47.8 24.0 13.0 9.2 35.8 2.4 2.8 3.8 5.9 1.7 7.2 2.8 2.2 4.8 3.3 2.0 2.8 2.0 2.4 3.5 3.0 3.0 2.3 2.6 4.4 7.3 1.0 2.6 1.1 1.7 10.5 15.0 16.7 10.0 12.6 4.6 9.5 4.8 10.1 10.6 SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067780-88113387 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 45.9;skeletal muscle: 103.7;tongue: 36.4" "Cell line enriched" "Detected in some" 5 "HSkMC: 5.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.6" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA062282 Enhanced "HPA062282: " "unprognostic (1.93e-2)" "unprognostic (2.49e-1)" "unprognostic (4.09e-2)" "unprognostic (8.51e-3)" "unprognostic (2.74e-1)" "unprognostic (3.91e-1)" "unprognostic (8.81e-3)" "unprognostic (1.40e-1)" 2.7 0.0 0.1 0.1 0.3 0.0 1.2 0.0 1.4 0.0 4.6 0.0 0.0 0.4 0.0 3.4 2.5 0.0 0.2 45.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.4 0.0 1.5 0.0 103.7 0.0 4.4 6.3 0.1 0.0 2.6 0.1 0.0 0.0 0.2 36.4 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.4 0.1 0.0 0.1 0.1 0.0 0.0 SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 75.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved "Intermediate filaments,Mitochondria,Cytosol" Cytosol "Intermediate filaments, Mitochondria" "HPA029023: AB_10601605" "unprognostic (8.53e-2)" "prognostic unfavourable (1.53e-5)" "unprognostic (5.98e-2)" "unprognostic (1.00e-2)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (2.24e-2)" "unprognostic (1.72e-2)" "unprognostic (1.90e-3)" "unprognostic (1.65e-1)" "unprognostic (9.44e-2)" "unprognostic (2.77e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (8.10e-2)" "unprognostic (6.37e-2)" 5.9 5.7 8.8 5.6 7.3 2.7 10.0 5.0 23.9 4.9 4.7 2.1 3.1 4.8 3.8 6.7 7.3 10.4 4.5 75.7 7.0 8.4 7.7 9.7 8.1 8.0 5.3 10.0 4.7 7.8 2.9 7.5 10.6 6.9 4.6 5.8 3.1 6.2 3.0 29.5 4.3 4.7 3.8 4.7 6.2 6.2 8.9 2.2 8.0 7.8 5.1 5.6 5.2 4.0 9.3 5.5 8.1 5.9 17.6 14.5 7.3 24.1 7.0 9.5 6.7 9.9 17.2 40.6 13.6 11.3 17.3 19.7 27.5 20.7 12.5 14.1 15.4 11.4 9.0 25.4 16.8 10.4 10.5 4.0 11.8 21.9 8.9 17.6 2.8 18.4 14.3 12.0 9.6 12.5 12.7 3.2 15.5 12.6 12.2 11.1 8.6 9.5 7.6 23.1 10.6 17.1 17.7 9.4 22.0 10.6 38.3 28.2 29.8 11.7 14.4 13.5 19.9 7.4 21.1 12.9 4.8 14.4 17.5 14.0 15.3 6.7 5.9 8.1 9.5 3.2 11.2 9.3 14.5 12.7 5.5 4.8 12.7 11.6 0.6 17.6 1.2 3.8 14.5 7.3 8.8 7.3 5.0 23.9 7.0 8.4 5.3 10.0 6.9 2.2 SMYD3 "KMT3E, ZMYND1, ZNFN3A1" ENSG00000185420 "SET and MYND domain containing 3" Q9H7B4 1 245749342-246507312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 92.9;K-562: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012229, HPA045821, HPA054352" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB012229: , HPA045821: , HPA054352: " "unprognostic (7.00e-3)" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.18e-3)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.25e-3)" "unprognostic (1.72e-3)" "unprognostic (4.53e-2)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (3.78e-5)" "unprognostic (9.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.58e-1)" 6.0 12.0 9.9 9.7 16.2 7.6 10.6 25.9 14.7 8.9 6.5 6.4 3.7 4.5 8.7 21.8 6.1 10.0 7.7 5.8 10.3 12.0 8.9 5.5 9.2 6.3 12.0 10.2 8.0 7.2 6.7 11.9 4.6 15.3 6.8 8.3 9.5 5.3 5.9 9.5 6.7 5.2 7.6 6.8 5.3 6.1 10.5 8.1 7.5 18.8 3.6 9.3 8.3 6.6 11.3 5.9 8.3 3.4 19.4 12.9 8.7 4.6 2.8 4.1 3.5 4.7 6.4 4.1 6.5 4.9 7.7 17.3 3.7 5.4 7.6 5.3 6.0 3.0 3.7 7.3 25.9 4.0 3.8 4.4 4.2 4.4 8.8 4.4 92.9 17.3 1.7 10.2 6.6 5.2 35.1 2.6 7.5 1.6 8.5 8.6 3.7 4.5 7.9 5.0 10.9 5.6 6.8 9.8 4.7 3.1 0.4 5.9 3.8 7.6 4.0 3.7 2.6 2.6 7.7 13.3 3.6 3.9 7.1 6.1 4.3 8.1 3.4 8.3 10.5 3.0 10.8 11.3 11.1 12.8 5.9 11.1 12.3 12.9 2.4 19.4 3.3 3.8 11.8 8.7 9.9 16.2 25.9 14.7 10.3 12.0 12.0 10.2 15.3 8.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 50.8;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favourable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favourable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.2 2.0 3.7 3.5 11.1 4.0 3.5 3.5 5.9 3.8 3.8 2.7 4.7 5.1 2.8 4.4 2.1 4.3 7.5 4.0 5.9 3.5 5.9 3.7 3.1 5.8 6.6 6.6 4.4 5.2 4.3 7.4 50.8 2.6 6.0 3.5 1.7 6.6 5.8 4.1 9.1 4.6 2.7 5.4 9.9 5.6 2.6 5.5 3.0 3.3 4.2 2.2 8.4 29.5 3.4 3.4 3.9 4.1 9.7 6.9 4.4 2.4 7.9 4.8 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 87.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: " "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 23.9 87.4 4.1 8.3 5.7 7.0 9.6 2.9 4.0 6.8 7.2 5.6 7.8 5.5 8.2 6.0 3.4 8.3 9.8 5.7 5.5 4.1 12.1 8.8 18.6 13.0 6.2 2.3 10.8 15.5 8.1 14.6 11.6 4.9 13.1 6.9 9.6 51.1 8.9 4.1 5.8 7.0 7.5 10.5 13.6 8.1 6.8 4.9 4.0 6.2 2.9 7.2 9.4 8.7 6.6 24.3 19.8 26.8 18.5 16.0 14.8 20.2 9.5 7.8 11.6 30.5 16.7 42.0 9.8 17.3 21.7 25.5 9.7 23.2 11.5 15.5 17.8 7.5 24.9 5.8 23.5 13.1 5.1 5.3 8.0 10.1 12.5 9.1 2.1 13.2 3.8 25.4 21.8 9.3 11.4 5.9 33.8 4.3 9.6 2.9 3.8 3.1 12.1 10.1 6.7 19.2 12.7 2.4 6.1 15.1 6.4 5.6 6.7 6.3 8.8 25.9 12.4 28.3 21.5 8.4 30.6 9.8 10.3 4.9 48.0 19.6 26.8 0.7 14.0 17.0 13.5 6.6 13.1 13.1 24.3 5.5 12.7 12.6 19.8 18.5 11.1 4.4 16.0 14.8 4.1 5.7 2.9 4.0 5.5 4.1 6.2 2.3 4.9 4.9 SOAT2 ACAT2 ENSG00000167780 "Sterol O-acyltransferase 2" O75908 12 53103518-53124538 "Enzymes, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 60.8" "Group enriched" "Detected in some" 5 "CACO-2: 9.6;Hep G2: 20.9;U-266/70: 7.0" "Group enriched" "Detected in some" 8 "liver cancer: 5.2;testis cancer: 5.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MAIT T-cell: 3.7;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.7;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 7 "T-cells: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (2.53e-1)" "unprognostic (2.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-4)" "unprognostic (3.88e-3)" "unprognostic (9.26e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (9.05e-2)" "unprognostic (2.37e-1)" "unprognostic (7.58e-3)" "unprognostic (3.28e-1)" 0.5 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.2 0.9 16.4 0.2 0.2 12.3 0.7 0.3 0.2 0.9 0.4 0.2 0.2 0.0 0.6 4.2 0.2 0.6 0.2 0.2 0.4 0.2 0.0 0.3 0.2 0.2 0.6 0.0 0.2 0.4 0.2 0.2 0.4 60.8 0.2 0.3 2.2 0.3 0.2 0.2 0.2 0.4 0.2 0.3 0.3 1.1 0.0 0.0 0.0 0.3 0.5 3.7 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 9.6 0.1 0.0 0.0 0.4 0.7 0.0 0.0 0.6 0.0 0.0 0.9 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.7 0.0 1.5 2.7 0.0 0.0 0.4 1.5 0.0 0.5 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell line enhanced" "Detected in many" "U-138 MG: 14.7;U-2 OS: 15.0;U-251 MG: 13.7;U-87 MG: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 4.0 0.3 2.1 3.5 1.1 3.2 1.4 8.7 5.8 5.8 4.4 3.1 1.4 0.0 3.2 6.4 5.1 1.7 2.0 2.3 0.5 1.3 0.4 3.7 0.2 1.5 0.0 0.7 9.3 3.1 5.3 1.3 0.0 3.0 0.0 4.2 1.1 0.1 12.4 4.4 1.6 2.1 4.7 0.7 5.7 0.0 2.3 10.9 0.6 0.0 0.1 0.3 0.1 0.1 14.7 15.0 1.7 13.7 0.5 0.0 0.1 16.6 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 33.7;U-251 MG: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 5 "olfactory region: 11.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavourable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 9.3 2.2 4.7 10.5 3.5 15.0 20.4 0.4 3.2 5.5 5.0 4.0 0.4 1.9 6.3 8.3 13.8 5.3 12.7 10.5 5.3 2.1 4.1 2.4 12.9 10.1 4.4 1.5 5.5 15.1 3.1 2.7 7.4 4.7 4.3 1.1 11.0 11.5 1.7 6.8 8.7 6.3 5.2 4.0 2.7 3.8 3.7 6.3 3.0 9.4 16.2 12.1 5.6 7.0 0.2 8.0 2.4 3.4 0.1 1.4 1.3 9.6 1.0 4.2 0.2 2.1 2.0 4.4 22.3 14.8 18.8 11.4 5.2 1.0 0.4 2.0 16.4 2.0 3.2 28.6 4.6 0.4 1.7 0.1 7.1 33.7 4.7 0.3 0.8 3.8 0.5 29.3 11.6 18.1 4.5 0.0 3.7 12.3 0.9 0.1 0.2 8.1 0.6 1.1 0.7 1.0 0.1 0.5 1.0 2.2 0.2 19.3 0.8 1.3 29.4 29.6 5.7 22.7 37.7 0.4 0.1 0.4 22.5 1.7 4.4 2.4 3.4 0.0 1.4 1.7 0.4 0.0 0.2 0.4 1.0 0.2 0.0 0.3 0.4 0.1 0.3 8.0 0.0 1.3 4.7 3.5 0.4 3.2 5.3 2.1 4.4 1.5 4.7 6.3 SPHK2 ENSG00000063176 "Sphingosine kinase 2" Q9NRA0 19 48619291-48630717 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065508 Supported Vesicles Vesicles "HPA065508: " "unprognostic (5.33e-2)" "unprognostic (4.11e-2)" "unprognostic (9.61e-2)" "prognostic unfavourable (5.19e-4)" "unprognostic (2.10e-1)" "unprognostic (7.19e-3)" "unprognostic (3.04e-1)" "unprognostic (4.45e-3)" "unprognostic (7.28e-2)" "unprognostic (2.80e-1)" "prognostic favourable (9.30e-4)" "unprognostic (1.25e-1)" "prognostic favourable (2.59e-5)" "unprognostic (1.18e-2)" "unprognostic (9.97e-2)" "unprognostic (4.21e-2)" "unprognostic (7.06e-2)" 9.3 8.9 12.6 9.9 13.0 5.2 5.1 13.6 22.0 7.2 12.9 13.4 4.9 33.2 7.4 4.2 4.9 7.3 7.8 4.7 22.5 14.8 19.3 15.2 6.1 8.7 26.3 14.9 9.1 7.2 15.0 9.5 4.1 22.3 8.7 6.2 7.2 7.5 8.0 6.1 4.3 22.2 4.9 14.1 8.4 11.3 17.2 13.7 4.0 9.1 3.1 5.3 6.2 12.4 10.4 7.4 12.5 9.4 7.2 7.0 4.2 4.0 11.7 4.4 8.0 4.8 2.0 8.3 4.4 3.7 5.2 6.2 20.0 5.4 7.6 3.0 2.8 3.0 4.1 3.6 0.7 8.6 9.6 8.4 5.1 7.0 7.6 5.4 9.3 3.7 1.9 3.6 2.5 2.8 5.5 6.8 2.5 4.2 12.6 33.3 5.8 5.7 11.7 3.5 4.9 2.4 2.7 15.9 12.6 4.2 6.7 4.2 3.6 3.6 4.5 7.4 4.1 5.8 8.8 13.1 15.1 8.4 4.3 6.2 6.7 12.5 8.3 3.6 6.0 9.4 5.9 6.5 4.8 5.8 7.4 10.4 6.6 7.0 3.3 7.2 7.4 6.6 4.6 4.2 12.6 13.0 13.6 22.0 22.5 14.8 26.3 14.9 22.3 13.7 SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115384 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: " "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favourable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" 16.4 17.7 13.3 11.4 17.1 9.9 16.8 19.9 17.6 20.3 17.2 20.9 18.1 14.0 17.3 15.1 30.5 19.2 15.5 11.4 13.9 15.3 19.0 13.5 14.8 10.6 18.0 12.2 35.3 15.8 23.6 23.1 28.3 20.5 14.5 18.8 12.0 18.5 13.3 9.4 20.1 17.8 15.1 20.8 10.7 16.0 19.8 14.1 9.7 26.2 16.0 16.5 17.4 20.9 9.3 21.0 21.1 22.1 10.2 15.2 16.0 18.1 16.4 11.4 9.5 27.9 21.7 19.7 19.1 24.4 16.5 17.9 10.3 37.9 10.0 12.2 24.1 47.6 12.3 16.2 19.2 11.5 7.1 9.2 9.3 10.0 21.0 15.2 12.5 19.6 19.6 17.0 18.6 15.0 21.5 12.5 18.7 19.5 9.5 3.8 15.3 12.0 10.6 13.8 7.6 16.4 11.1 9.3 8.6 25.7 19.7 11.6 10.1 9.0 19.0 16.1 12.4 18.5 13.3 9.0 12.3 5.6 19.2 7.5 19.3 14.6 22.1 11.9 11.5 21.6 11.0 8.9 11.6 11.6 21.0 9.3 14.2 10.7 21.1 10.2 19.2 10.8 15.2 16.0 13.3 17.1 19.9 17.6 13.9 15.3 18.0 12.2 20.5 14.1 SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616773 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027552 Approved Mitochondria Mitochondria "HPA027552: AB_10601717" "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavourable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favourable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" 30.0 12.8 15.4 11.4 27.0 27.3 25.6 6.9 18.5 15.3 17.0 32.4 8.5 13.4 10.2 7.6 22.8 13.7 11.1 7.8 20.8 14.1 17.1 7.2 12.2 17.5 33.1 13.3 10.2 7.6 12.8 9.8 18.8 21.2 8.2 18.8 6.0 16.6 9.6 5.5 11.3 15.8 11.0 47.6 23.5 18.8 4.7 34.9 10.0 10.3 8.8 12.0 13.2 17.1 4.8 18.2 15.1 18.2 10.0 4.2 6.9 11.9 7.9 6.1 6.6 6.3 7.9 10.3 17.8 13.2 12.3 12.9 10.0 26.7 12.0 4.5 18.1 14.8 16.1 10.0 18.7 5.2 4.7 33.9 6.1 5.9 5.3 3.4 11.3 5.1 4.9 8.0 8.9 17.3 6.6 5.8 7.0 10.3 9.0 11.7 3.9 7.1 9.7 6.2 4.1 14.2 26.9 5.9 7.4 6.4 21.5 6.7 26.4 6.3 10.8 11.3 8.1 4.1 4.1 3.3 5.4 8.1 7.5 12.2 6.4 8.8 18.2 15.1 3.8 13.8 3.5 4.1 3.2 4.2 18.2 4.8 2.2 3.6 11.2 10.0 16.7 6.5 3.3 6.9 15.4 27.0 6.9 18.5 20.8 14.1 33.1 13.3 21.2 34.9 SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008979-13169103 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "placenta: 154.0" "Cell line enhanced" "Detected in many" "Karpas-707: 16.0;RPTEC TERT1: 21.4;U-2197: 14.9;U-87 MG: 28.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "pons and medulla: 10.5" "Group enriched" "Detected in some" 5 "MAIT T-cell: 3.0;NK-cell: 4.1" "Group enriched" "Detected in many" 13 "NK-cells: 4.1;T-cells: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA044247, HPA048079" Enhanced Approved Microtubules Microtubules "HPA044247: , HPA048079: " "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favourable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" 3.2 4.5 1.3 1.6 2.2 0.0 4.3 1.7 1.7 4.3 5.0 2.2 4.4 8.3 4.8 9.6 5.6 3.4 5.8 4.8 2.0 1.5 15.6 11.9 5.7 0.7 2.5 2.2 4.3 3.8 10.2 4.2 154.0 10.5 4.5 3.8 3.8 7.8 5.8 1.0 25.1 9.0 3.0 6.9 1.9 2.2 4.2 1.4 5.7 24.3 3.6 1.9 4.8 6.0 0.0 0.2 0.1 0.0 4.1 3.0 0.2 0.6 1.1 0.8 0.0 7.0 10.1 5.4 0.0 1.5 1.0 4.1 8.7 4.4 0.0 0.5 0.2 12.0 0.0 3.3 1.4 0.0 0.0 0.0 2.8 12.3 0.6 0.0 0.1 5.7 10.4 4.0 1.3 0.6 0.0 16.0 11.3 0.2 0.0 0.0 0.0 1.4 1.1 2.0 7.0 21.4 8.6 0.0 0.1 0.1 1.1 0.0 8.9 0.2 1.5 4.5 1.5 14.9 1.0 0.1 0.0 0.0 28.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 3.0 0.0 0.4 0.1 0.0 0.0 0.7 0.1 0.1 4.1 0.0 0.2 0.0 0.2 1.3 2.2 1.7 1.7 2.0 1.5 2.5 2.2 10.5 1.4 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 35.5;HBEC3-KT: 33.0;PC-3: 32.1;RT4: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 5.3;non-classical monocyte: 4.4" "Group enriched" "Detected in many" 6 "dendritic cells: 3.0;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Plasma membrane,Cell Junctions,Cytosol" 20000000 "Plasma membrane, Cell Junctions" Cytosol "CAB004023: AB_2106059, HPA030875: " "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavourable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavourable (1.63e-4)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favourable (5.22e-5)" 6.9 17.5 12.8 11.1 12.0 5.4 9.9 6.4 16.0 16.0 16.4 3.5 15.1 29.5 20.3 9.7 16.2 14.2 42.1 5.8 11.3 6.6 13.4 2.9 10.4 7.0 3.3 9.9 15.8 19.1 6.6 11.3 6.3 5.1 19.9 13.1 13.1 7.5 22.5 3.4 7.7 28.1 27.2 3.6 12.2 29.8 27.3 4.8 4.0 6.6 10.5 10.4 26.4 20.0 0.3 3.0 0.1 5.3 0.6 0.1 1.6 7.6 35.5 8.1 7.3 3.1 4.9 17.0 7.1 6.1 8.6 5.5 13.3 6.9 0.2 4.4 12.8 14.0 4.9 33.0 3.4 0.0 4.4 1.9 1.2 20.7 7.4 0.1 3.0 5.3 11.2 5.6 7.5 7.8 0.2 0.0 1.4 5.2 1.8 0.2 3.8 32.1 8.3 2.1 0.2 3.6 34.0 7.6 27.5 8.0 11.3 8.8 10.1 2.8 11.5 10.4 7.0 3.8 6.3 0.1 0.2 0.1 7.3 0.0 7.7 0.0 2.6 0.0 0.0 5.3 0.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.1 0.6 4.4 3.0 0.1 1.6 12.8 12.0 6.4 16.0 11.3 6.6 3.3 9.9 5.1 4.8 SRM "SPS1, SRML1" ENSG00000116649 "Spermidine synthase" P19623 1 11054584-11060024 "Enzymes, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 107.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015746 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA015746: AB_1857472" "unprognostic (4.97e-2)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (2.52e-2)" "unprognostic (1.75e-1)" "unprognostic (1.97e-1)" "prognostic unfavourable (2.25e-5)" "unprognostic (2.11e-2)" "unprognostic (2.44e-1)" "unprognostic (3.58e-2)" "unprognostic (3.01e-1)" "unprognostic (3.45e-1)" "prognostic unfavourable (3.80e-8)" "unprognostic (1.74e-2)" "unprognostic (8.98e-3)" "unprognostic (1.36e-1)" "unprognostic (2.98e-2)" 26.7 17.7 20.3 29.0 35.4 15.2 16.9 10.2 30.8 14.3 13.3 14.0 11.5 10.8 18.8 9.8 17.7 15.8 14.2 24.9 19.6 16.9 13.9 45.3 14.0 31.0 15.3 15.0 22.8 107.4 8.0 14.5 14.8 15.6 13.1 11.7 15.0 36.0 17.6 43.6 18.2 9.8 22.9 11.7 21.1 14.5 14.4 14.1 17.9 11.9 21.2 20.8 20.2 19.8 10.7 10.2 0.3 6.0 5.0 10.3 2.0 24.9 36.3 12.1 40.4 24.1 26.1 19.0 38.8 19.9 55.5 29.8 44.7 15.1 48.2 22.9 33.6 19.6 38.6 31.2 18.4 23.7 58.3 30.4 40.2 50.4 35.5 50.9 27.9 26.2 22.6 53.7 47.1 23.4 49.4 40.9 26.9 54.7 43.4 44.5 26.3 70.4 32.7 12.5 78.7 19.7 9.9 23.3 22.3 20.0 43.3 30.3 15.1 25.9 19.4 36.2 28.5 62.7 43.5 33.0 33.2 72.2 25.2 68.5 41.7 0.0 5.4 0.3 7.0 6.0 10.3 10.7 7.1 9.1 6.4 9.3 8.4 9.7 0.2 5.0 3.1 10.2 7.5 2.0 20.3 35.4 10.2 30.8 19.6 16.9 15.3 15.0 15.6 14.1 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 10.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.7;HaCaT: 2.6;MCF7: 4.9;RT4: 10.1;T-47d: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 8 "B-cells: 1.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: " "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.3 0.0 0.3 0.5 0.3 0.0 1.1 1.1 0.3 0.3 1.8 0.3 0.3 0.4 0.3 10.2 0.4 0.0 0.3 0.3 0.3 0.0 0.9 0.3 0.3 0.3 0.3 0.3 0.3 2.7 0.0 0.3 0.3 0.3 2.2 0.0 0.3 2.5 0.3 0.3 1.7 0.8 0.3 0.3 2.5 4.2 0.9 0.3 0.3 0.3 0.3 0.8 1.5 0.3 1.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 5.7 0.2 2.3 0.0 2.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.2 0.0 0.8 0.0 0.2 0.0 0.0 10.1 0.8 1.0 0.3 2.1 0.4 2.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 1.1 0.3 0.3 0.0 0.3 0.3 0.3 0.3 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavourable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavourable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 13.5 7.1 8.1 15.4 11.7 32.1 11.7 22.5 17.8 12.8 23.8 7.8 10.8 20.3 15.2 7.9 24.9 8.9 10.8 8.7 8.9 7.8 17.8 18.9 14.9 14.6 8.0 8.3 9.5 26.0 11.7 17.7 27.9 9.6 10.5 28.7 12.4 17.6 9.4 19.9 26.2 25.7 11.3 7.9 19.0 13.9 32.7 7.6 21.0 8.5 17.0 19.8 15.2 15.7 4.3 2.8 24.6 3.4 5.0 6.7 2.9 29.3 11.1 16.4 24.5 9.2 12.0 20.8 18.0 17.4 16.9 18.0 31.3 9.9 39.2 15.3 11.1 15.1 32.0 21.5 30.3 26.7 23.1 20.6 13.1 27.1 8.2 30.4 10.1 7.7 11.7 19.4 25.4 21.1 43.6 16.6 14.1 10.4 31.3 23.7 13.4 12.2 22.1 19.7 24.2 16.9 49.3 35.1 12.9 18.5 17.6 12.5 9.9 20.3 15.2 15.9 12.4 10.7 22.6 9.8 21.6 36.8 6.3 35.4 14.1 24.5 2.1 13.7 4.3 2.5 6.1 4.3 5.7 5.7 2.8 3.3 4.8 5.2 24.6 5.0 3.4 1.6 6.7 2.9 8.1 11.7 22.5 17.8 8.9 7.8 8.0 8.3 9.6 7.6 SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015522: AB_1857479, HPA020876: AB_1857480" "unprognostic (9.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (4.64e-2)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (7.95e-2)" "unprognostic (4.72e-2)" "unprognostic (2.87e-2)" "unprognostic (3.44e-1)" 9.9 12.1 24.8 10.1 27.6 7.1 13.3 28.4 47.1 12.7 9.4 21.0 7.8 8.2 13.2 11.9 11.9 10.9 11.6 10.4 26.4 28.6 10.3 10.1 9.2 11.5 27.2 30.2 13.0 10.5 11.9 15.3 12.0 27.3 14.0 10.9 7.9 10.1 11.1 7.9 16.9 8.2 13.3 23.1 12.0 11.3 69.3 32.3 22.1 11.3 4.7 14.0 13.6 9.7 12.2 7.3 58.2 8.1 10.0 11.9 6.0 13.1 8.7 13.9 27.6 14.9 16.9 7.8 12.8 15.1 12.9 15.1 6.8 11.2 8.3 16.4 16.6 7.9 14.1 13.6 16.5 14.4 12.5 11.8 8.2 5.9 17.3 11.2 17.7 11.7 25.3 10.9 20.6 22.1 11.6 34.2 14.2 24.8 41.5 8.5 11.5 9.6 13.5 15.4 18.2 18.6 20.4 20.5 14.2 14.6 22.0 13.5 8.2 7.8 14.5 23.8 17.4 22.6 12.0 37.6 37.0 20.5 9.3 11.6 17.7 11.2 8.1 26.0 11.9 5.5 7.1 12.2 9.0 8.9 7.3 11.6 8.5 9.7 58.2 10.0 6.2 6.4 10.1 6.0 24.8 27.6 28.4 38.7 26.4 28.6 27.2 30.2 27.3 32.3 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 73.4" "Cell line enhanced" "Detected in many" "RH-30: 30.8;U-266/70: 12.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 1.8 1.3 0.9 1.8 0.8 0.3 7.7 1.5 0.9 4.5 1.1 0.2 1.3 2.5 3.3 2.6 0.7 1.7 16.7 2.0 1.8 0.2 0.2 0.4 0.8 2.0 0.7 0.7 0.7 1.0 5.8 0.3 1.1 2.8 0.8 0.9 2.9 0.5 73.4 2.3 1.3 4.0 2.0 0.8 1.3 0.5 0.9 0.3 0.6 18.3 1.6 2.0 0.8 0.4 2.6 0.9 0.3 0.1 0.6 0.3 3.2 4.3 0.7 2.2 0.0 0.1 1.0 0.4 0.0 0.2 0.0 3.6 0.6 3.2 0.4 0.3 0.9 0.0 0.1 0.0 2.8 3.0 1.7 2.7 0.5 0.0 0.8 5.0 2.7 0.0 0.0 0.0 0.0 2.1 3.8 0.8 6.9 0.6 4.7 0.8 1.2 1.5 30.8 0.9 0.0 1.4 5.2 2.5 0.0 2.3 1.0 2.9 3.7 0.0 1.2 2.8 2.3 0.4 12.8 2.0 2.2 0.6 6.1 1.6 0.8 0.3 0.2 0.5 0.1 0.6 0.2 0.1 0.1 0.0 0.4 0.1 0.1 0.9 0.1 0.0 2.6 0.0 0.3 1.3 1.8 7.7 1.5 2.0 1.8 2.0 0.7 1.1 0.9 ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 47.8;RT4: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040466 Approved "Intracellular and membrane" 290000 "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" 14.4 14.4 5.1 11.8 3.6 10.2 7.8 3.7 6.5 9.8 5.4 4.1 18.1 1.8 8.5 11.8 9.0 9.0 17.0 35.4 4.2 3.4 23.1 44.5 11.9 12.4 4.7 2.5 10.3 8.2 4.4 7.6 49.8 6.4 7.1 2.9 11.2 18.2 15.1 20.9 4.0 6.5 12.3 3.9 17.3 9.4 5.0 1.4 6.3 40.2 7.9 16.8 14.0 14.3 22.7 7.0 21.3 9.8 21.9 19.9 9.5 4.7 2.5 1.0 2.9 10.3 5.4 5.3 5.4 13.1 2.1 1.6 4.4 5.3 1.1 3.7 10.0 1.4 3.4 4.0 1.9 13.3 0.6 9.9 7.6 8.8 7.9 2.0 7.9 6.3 2.0 7.6 4.2 9.2 0.1 15.4 1.5 5.0 2.8 2.7 0.7 47.8 3.3 1.3 8.1 0.9 36.8 0.2 0.8 2.4 8.2 2.5 1.5 2.7 8.9 6.5 10.3 5.6 2.3 19.0 13.6 1.2 14.8 6.9 6.6 20.5 4.7 21.3 14.4 4.5 13.3 12.8 14.6 16.4 2.9 22.7 19.9 18.5 8.6 21.9 9.8 7.0 8.9 9.5 5.1 3.6 3.7 6.5 4.2 3.4 4.7 2.5 6.4 1.4 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375978-70439237 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favourable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavourable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 12.6 9.1 9.3 17.2 11.9 14.3 8.9 24.1 10.6 11.3 8.8 5.1 9.3 9.2 13.9 5.6 5.8 9.0 6.8 9.2 10.4 6.0 8.8 12.9 9.3 14.9 5.1 4.7 13.6 4.2 8.8 7.2 8.8 6.8 7.5 4.7 9.9 4.9 9.0 33.3 6.0 10.5 12.0 4.0 17.7 5.4 9.6 5.9 16.0 6.6 4.9 12.6 9.1 12.0 3.2 14.3 11.2 2.2 2.8 4.2 1.1 1.4 8.3 7.2 9.6 3.9 5.3 1.7 5.9 6.3 6.6 3.3 4.9 3.3 4.0 10.6 6.4 1.0 2.9 2.4 3.1 9.5 4.6 17.2 3.4 7.4 4.8 6.2 28.3 4.1 1.4 6.6 1.2 9.0 23.4 3.9 3.6 0.6 6.6 17.1 9.8 4.5 12.6 2.7 5.4 4.4 1.1 3.2 9.5 14.7 0.3 6.5 1.6 7.0 9.6 8.4 10.0 3.5 4.3 8.2 3.2 8.2 9.1 5.2 11.6 2.7 2.0 5.7 2.0 2.2 1.9 1.7 2.4 2.2 1.0 3.2 4.2 3.3 11.2 2.8 1.3 14.3 2.7 1.1 9.3 11.9 24.1 10.6 10.4 6.0 5.1 4.7 6.8 5.9 ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" 11.6 9.0 13.0 8.9 16.5 9.9 12.8 15.5 20.4 9.0 10.3 9.0 8.0 3.2 10.8 10.7 8.7 8.3 7.2 16.9 12.8 13.9 6.7 9.1 7.2 7.6 12.0 10.4 13.3 7.5 6.9 10.9 6.7 11.6 8.8 5.1 9.0 8.0 13.9 71.5 7.4 3.8 15.9 7.7 6.0 5.9 14.5 10.3 3.2 8.1 17.8 4.8 8.1 7.0 7.1 7.0 5.8 4.2 4.7 7.6 6.1 2.4 1.9 14.4 6.8 11.3 14.3 1.8 9.4 19.6 8.8 8.5 1.7 4.0 4.6 4.9 12.1 2.4 1.3 6.2 10.6 5.3 3.2 8.7 6.1 4.6 9.5 3.9 4.4 7.6 4.7 6.4 14.1 6.9 5.1 8.5 16.3 1.6 4.0 7.5 5.7 5.0 6.8 1.9 3.1 7.1 1.6 5.8 8.6 3.7 1.4 8.2 2.2 19.0 6.6 5.3 2.5 8.6 9.5 6.8 3.9 4.3 7.8 9.5 9.8 2.9 4.2 2.5 6.8 2.5 6.1 4.5 4.4 5.1 3.0 7.1 7.6 5.7 5.8 4.7 3.7 7.0 5.2 6.1 13.0 16.5 15.5 20.4 12.8 13.9 12.0 10.4 11.6 10.3 ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 74.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 44.7;WM-115: 101.5" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 31.3;neutrophil: 22.8;plasmacytoid DC: 29.6" "Group enriched" "Detected in many" 11 "dendritic cells: 29.6;granulocytes: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" "HPA049827: " "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" 7.8 38.0 6.2 6.5 12.2 7.8 12.9 4.0 13.6 8.3 27.0 26.4 5.1 2.0 6.0 42.1 25.5 6.0 11.4 26.5 8.6 6.2 16.7 11.5 12.4 9.0 18.7 9.0 39.3 5.1 0.8 5.6 74.2 13.8 12.1 31.5 35.7 14.4 8.0 1.9 5.6 3.8 11.0 23.0 17.0 4.8 18.8 12.4 2.2 6.1 4.3 10.1 21.1 13.2 0.1 29.6 31.3 2.6 1.2 1.7 1.8 4.8 4.0 3.2 2.7 9.4 7.8 7.9 5.6 10.9 5.1 3.5 2.3 8.4 1.4 4.3 8.9 7.6 6.6 3.7 4.0 5.2 1.9 12.4 10.1 2.7 6.1 14.8 25.4 6.2 5.9 7.7 12.2 6.8 7.7 3.7 6.3 20.0 4.7 15.2 2.0 26.5 4.8 9.8 0.6 1.1 14.0 6.0 3.8 6.2 37.7 44.7 13.1 9.8 2.5 12.3 2.8 8.7 10.6 0.3 0.8 0.7 5.6 22.8 101.5 31.3 1.6 0.2 1.7 2.6 1.6 0.1 0.6 1.1 6.6 0.0 0.1 0.8 22.8 1.2 1.2 29.6 0.0 1.8 6.2 12.2 4.0 13.6 8.6 6.2 18.7 9.0 13.8 12.4 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 40.1" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;RT4: 21.7;SK-MEL-30: 17.9;U-266/84: 18.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles Vesicles "HPA034708: AB_10601594, HPA040425: , HPA068928: " "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavourable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favourable (4.99e-4)" "prognostic favourable (4.48e-4)" 8.0 40.1 15.3 7.2 18.5 4.1 4.2 9.9 34.9 3.3 3.8 18.8 0.0 2.7 8.0 2.9 2.9 4.9 11.8 2.1 14.8 12.0 2.4 7.0 18.0 11.5 14.0 13.4 7.2 2.9 1.5 7.4 24.1 18.1 4.8 5.0 18.7 4.8 2.2 9.5 5.0 3.4 6.2 18.0 11.1 4.1 9.0 13.4 5.5 36.7 0.4 6.9 30.9 7.8 2.5 1.1 1.3 6.1 1.4 1.8 0.5 0.1 12.5 1.1 25.6 10.6 5.7 3.8 2.7 8.4 2.7 2.4 0.2 9.1 0.3 0.0 4.6 0.4 1.6 2.9 3.3 0.1 1.5 0.2 0.5 0.4 8.5 0.1 3.7 3.2 0.4 1.0 0.4 6.4 0.3 14.2 8.6 0.8 0.8 1.4 0.1 0.0 1.6 8.1 5.0 1.4 21.7 1.8 1.8 0.1 0.0 17.9 0.1 0.5 2.1 0.0 1.3 0.0 0.2 14.3 18.9 0.2 2.0 2.6 12.9 0.9 1.8 0.1 1.4 6.1 1.8 2.5 0.8 0.9 1.1 1.5 0.7 0.8 1.3 1.4 5.1 0.4 0.3 0.5 15.3 18.5 9.9 21.9 14.8 12.0 14.0 13.4 18.1 13.4 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930485-187078553 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.4" "Cell line enhanced" "Detected in many" "Daudi: 31.9;U-266/70: 101.7;U-266/84: 130.0;U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" 15000000 580000 "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 10.6 6.5 11.8 16.7 15.4 4.0 10.5 2.8 11.8 19.1 11.4 22.7 4.2 4.3 8.6 4.3 4.4 8.6 5.7 10.6 10.7 7.6 19.1 161.4 10.9 27.6 18.2 7.6 4.5 4.1 20.5 5.7 5.5 13.7 19.5 14.2 5.4 17.7 4.6 5.7 4.5 12.6 5.8 22.3 27.0 8.5 2.4 15.1 19.4 19.4 4.0 41.6 13.2 14.3 33.6 4.6 6.9 8.9 8.5 29.3 16.9 0.7 0.7 3.0 2.2 0.2 0.0 4.7 0.2 0.4 0.1 0.3 0.2 0.2 31.9 2.6 0.0 1.4 18.8 1.9 0.2 1.5 0.8 1.2 0.1 15.5 0.1 3.0 10.0 0.2 4.1 0.0 1.7 11.0 6.4 3.0 0.9 1.3 2.2 2.1 6.7 0.9 5.1 0.0 1.0 1.4 0.0 4.9 0.5 0.1 3.6 8.3 5.3 2.1 4.2 0.0 0.4 0.0 0.3 101.7 130.0 47.4 0.1 6.0 11.0 6.9 2.7 1.1 16.5 5.2 15.0 32.7 18.2 13.8 4.6 33.6 29.3 20.2 1.3 8.5 8.9 4.2 14.2 16.9 11.8 15.4 2.8 11.8 10.7 7.6 18.2 7.6 13.7 15.1 ST6GAL2 "KIAA1877, SIAT2, St6gal2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;thyroid gland: 34.0" "Cell line enhanced" "Detected in some" "A549: 5.7;NTERA-2: 4.9;PC-3: 6.5;RPMI-8226: 10.2;SCLC-21H: 6.8;U-138 MG: 8.3;U-266/70: 10.9" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: AB_1857528" "unprognostic (2.08e-1)" "unprognostic (5.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (6.44e-3)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-4)" "unprognostic (4.56e-3)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (7.01e-4)" "unprognostic (4.70e-4)" "unprognostic (4.06e-2)" "unprognostic (2.83e-1)" "unprognostic (2.07e-2)" 1.2 0.7 14.1 0.7 5.6 1.5 1.3 2.3 16.7 2.1 1.5 4.1 1.7 0.7 3.7 1.9 2.7 1.2 12.7 1.9 5.4 4.0 1.1 3.4 1.2 0.9 3.8 7.1 0.9 0.5 0.5 0.3 2.3 4.2 1.6 3.3 0.0 1.6 1.6 0.7 1.3 0.7 2.8 1.9 0.6 0.9 7.9 1.5 0.0 34.0 1.6 0.8 1.5 1.4 0.7 0.6 1.8 0.5 1.0 0.7 0.5 0.0 5.7 3.2 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.4 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.9 6.5 0.0 0.0 10.2 0.2 0.0 6.8 4.4 0.0 0.1 0.0 0.0 0.1 0.0 8.3 0.1 0.2 0.0 10.9 0.2 0.1 0.0 0.0 0.0 1.4 0.5 0.4 0.6 0.3 0.5 0.4 0.4 0.5 0.2 0.7 0.5 0.7 1.8 1.0 0.3 0.6 0.5 0.5 14.1 5.6 2.3 14.8 5.4 4.0 3.8 7.1 4.2 1.5 ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643838 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.4" "Cell line enhanced" "Detected in some" "EFO-21: 6.1;HaCaT: 6.8;HEL: 10.9;K-562: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2;naive CD4 T-cell: 4.2" "Lineage enriched" "Detected in single" 25 "T-cells: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" 1200000 "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: AB_1857529" "unprognostic (4.59e-2)" "unprognostic (8.60e-3)" "unprognostic (5.32e-3)" "unprognostic (1.86e-3)" "unprognostic (6.31e-3)" "prognostic favourable (2.54e-5)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.58e-2)" "unprognostic (8.64e-3)" "unprognostic (2.81e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (5.87e-3)" "unprognostic (5.58e-2)" 1.4 0.3 1.2 13.9 2.6 0.7 1.3 0.8 3.2 20.4 50.9 3.1 0.3 19.8 6.3 1.8 19.6 1.5 26.6 4.1 1.6 1.3 0.4 1.1 5.7 1.1 1.8 1.2 2.0 1.1 0.1 0.4 1.7 3.7 2.6 69.4 0.1 20.8 1.4 0.9 0.6 49.0 1.9 1.5 6.0 23.9 4.0 0.6 0.0 0.5 4.5 21.6 1.9 2.6 0.0 0.0 0.4 0.0 0.0 11.2 1.1 0.1 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 6.1 0.0 6.8 0.0 1.8 0.0 0.0 0.0 10.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 32.6 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.2 0.2 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 1.4 1.1 1.2 2.6 0.8 3.2 1.6 1.3 1.8 1.2 3.7 0.6 ST6GALNAC4 "SIAT3C, SIAT7D, ST6GALNACIV" ENSG00000136840 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4" Q9H4F1 9 127907886-127917038 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 58.8;pancreas: 61.0" "Cell line enhanced" "Detected in many" "HDLM-2: 34.9;RPMI-8226: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "plasmacytoid DC: 58.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009042 Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA009042: AB_1079963" "unprognostic (2.05e-3)" "unprognostic (2.32e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-2)" "unprognostic (3.18e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (8.63e-7)" "unprognostic (1.62e-2)" "unprognostic (4.26e-1)" "prognostic unfavourable (5.12e-4)" "unprognostic (1.04e-1)" "unprognostic (3.04e-1)" "prognostic unfavourable (8.39e-4)" "unprognostic (1.30e-3)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (2.03e-2)" 8.0 7.8 5.6 7.9 5.6 26.2 12.1 9.8 8.5 9.2 9.3 4.8 28.9 11.7 8.7 9.6 6.9 8.7 12.2 18.4 5.2 3.4 9.4 5.0 13.5 9.7 4.2 4.7 14.9 61.0 2.4 9.4 4.3 4.8 6.1 5.4 4.8 9.3 30.0 12.6 4.0 9.7 6.1 3.9 18.2 7.2 4.3 4.7 4.7 6.3 5.9 12.5 8.9 8.3 6.7 58.8 0.8 3.2 4.3 3.4 2.4 3.1 5.4 1.4 6.9 9.7 7.4 1.0 5.5 6.1 5.6 3.3 3.0 5.8 20.1 8.4 6.8 7.7 2.8 5.8 0.9 34.9 2.4 6.4 17.2 11.4 11.9 0.5 6.7 9.1 6.2 5.0 4.5 14.9 4.6 13.5 2.7 1.4 1.2 0.7 1.6 13.3 6.0 3.6 49.4 5.7 0.1 11.8 2.6 8.0 17.3 1.0 3.5 4.1 10.6 4.6 5.3 14.3 8.6 21.9 11.3 6.3 9.2 2.8 0.6 0.8 2.1 0.0 2.9 1.9 3.3 6.7 1.8 3.4 2.8 4.9 2.3 3.1 0.2 4.3 3.2 58.8 3.3 2.4 5.6 5.6 9.8 8.5 5.2 3.4 4.2 4.7 4.8 4.7 ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell line enhanced" "Detected in some" "AF22: 9.0;ASC TERT1: 6.0;RPTEC TERT1: 4.6;SK-MEL-30: 8.3;WM-115: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "granulocytes: 1.2;T-cells: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved "HPA026775: AB_1857534" "unprognostic (1.98e-1)" "unprognostic (5.76e-3)" "unprognostic (1.79e-1)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-3)" "unprognostic (1.76e-2)" "unprognostic (1.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.99e-1)" "unprognostic (6.37e-3)" "unprognostic (2.80e-2)" "unprognostic (1.07e-8)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (5.28e-2)" "unprognostic (3.16e-2)" 1.7 7.6 7.0 5.3 6.2 2.3 5.9 20.2 13.0 3.5 5.4 2.3 2.3 0.4 4.5 1.4 3.0 2.3 2.4 4.4 7.6 8.5 1.1 0.6 3.8 8.6 7.6 6.5 2.6 1.2 7.2 0.6 0.4 9.4 6.6 3.5 1.5 3.2 4.4 1.0 4.3 2.1 6.3 10.9 2.7 2.1 1.0 4.8 0.2 1.4 0.5 9.2 6.7 3.1 0.3 0.2 1.2 0.2 0.3 3.0 0.6 0.0 0.5 9.0 0.0 1.4 6.0 0.9 0.0 0.0 0.1 0.4 0.3 0.1 1.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 0.0 1.1 0.1 0.1 0.0 0.3 0.1 0.5 0.9 0.1 0.9 0.2 0.0 0.6 0.2 0.0 1.2 0.3 2.3 0.0 0.0 0.2 0.2 4.6 0.0 0.1 0.2 0.0 0.1 8.3 0.7 0.1 0.0 0.7 0.9 0.1 1.4 0.7 0.5 0.7 1.4 0.1 8.9 1.2 0.2 0.2 0.4 0.1 0.9 0.1 2.9 2.3 0.1 0.3 0.4 1.0 0.9 0.3 0.2 0.2 3.0 0.6 7.0 6.2 20.2 13.0 7.6 8.5 7.6 6.5 9.4 4.8 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042073-172188386 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell line enhanced" "Detected in all" "WM-115: 51.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 27.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" 24000 "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: " "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favourable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 15.0 4.7 2.6 25.8 4.4 38.3 13.5 27.5 3.0 3.6 5.0 4.8 3.4 4.7 4.4 4.4 3.6 4.2 11.0 9.0 2.4 2.5 5.3 4.5 15.4 40.9 5.4 1.9 3.5 4.1 2.5 3.7 16.2 4.5 4.3 4.0 5.6 7.8 2.5 3.1 9.0 12.2 5.7 4.6 33.0 6.2 13.1 3.5 20.6 4.6 3.1 23.7 9.5 11.3 5.0 10.3 22.3 30.8 7.4 18.0 15.6 7.7 7.2 4.5 6.7 5.2 6.5 11.5 10.1 8.4 7.3 6.8 3.7 10.2 9.3 5.4 12.4 9.0 2.0 12.3 4.8 12.2 3.3 11.2 3.0 2.1 7.5 11.3 13.3 6.4 2.6 9.9 8.3 6.3 1.0 13.1 5.1 12.4 8.1 25.5 1.8 5.7 13.4 3.5 6.2 3.0 9.8 3.0 3.7 5.8 8.1 27.6 2.9 24.0 8.7 8.2 4.1 5.7 5.4 11.1 16.3 5.9 10.8 17.5 51.5 7.1 10.8 10.0 18.0 21.4 13.3 5.0 9.4 12.8 10.3 4.4 5.6 9.6 22.3 7.4 30.8 3.2 12.2 15.6 2.6 4.4 27.5 3.0 2.4 2.5 5.4 1.9 4.5 3.5 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: " "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favourable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favourable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.1 10.2 7.8 14.7 7.4 6.7 16.5 10.3 10.8 9.7 10.4 8.3 14.8 13.9 11.5 10.8 13.7 7.6 15.9 3.0 25.9 18.7 14.2 0.6 10.5 15.9 14.2 23.8 12.2 11.6 7.5 11.1 9.7 26.5 19.1 5.5 15.8 13.7 14.4 14.9 12.6 21.7 8.3 15.5 8.8 15.5 18.1 13.0 0.0 7.7 11.1 12.1 23.4 13.1 10.1 11.4 19.7 16.4 37.6 15.8 10.4 10.0 19.0 10.3 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Approved Cytosol Cytosol "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favourable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 10.2 19.0 15.7 12.8 20.3 13.3 14.6 8.8 21.0 11.5 16.2 15.2 20.5 17.2 11.4 22.1 16.0 18.3 15.5 13.0 14.5 11.9 19.5 30.1 11.4 24.6 14.2 13.2 13.2 24.5 16.5 15.1 14.0 13.3 14.3 13.7 12.8 19.0 16.3 9.9 12.2 14.2 11.5 12.3 15.9 16.8 18.9 12.7 27.2 19.8 12.8 17.0 12.9 10.3 7.9 7.8 5.8 7.6 14.5 11.2 9.7 7.3 9.6 8.4 7.2 21.2 20.7 9.7 9.5 13.1 8.1 8.1 11.2 16.4 4.2 13.3 15.7 7.6 9.8 15.7 4.3 10.4 11.4 9.6 8.7 9.6 19.2 9.1 11.2 22.0 25.3 11.1 29.4 9.8 11.9 11.6 13.8 13.5 9.9 19.8 7.9 5.9 9.3 9.5 12.4 16.8 8.5 6.8 8.7 3.4 13.5 19.3 14.1 19.2 7.5 11.0 7.8 8.9 9.0 14.3 6.1 10.1 12.2 9.6 9.6 2.0 7.6 5.8 6.0 4.2 6.8 7.8 7.5 11.2 7.8 7.9 7.8 10.0 5.2 14.5 3.6 6.7 8.4 9.7 15.7 20.3 8.8 21.0 14.5 11.9 14.2 13.2 13.3 12.7 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA018138, HPA037979" Uncertain Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.5 5.7 5.2 3.5 6.5 8.6 2.1 16.5 17.8 9.0 9.2 4.9 3.3 7.3 26.0 13.7 9.4 3.9 21.9 12.6 18.0 4.4 6.5 4.3 6.1 4.8 11.2 4.4 7.0 25.8 11.9 10.9 16.8 7.6 25.2 10.3 2.1 18.2 5.2 8.0 18.7 6.3 3.3 14.5 15.7 3.4 2.8 6.3 7.4 3.4 4.8 4.0 5.7 16.8 19.6 7.5 11.6 18.4 15.3 7.6 10.6 19.9 9.9 31.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell line enhanced" "Detected in many" "Daudi: 35.5;HMC-1: 36.0;Karpas-707: 33.4;U-698: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavourable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.1 2.2 3.3 1.2 14.7 5.6 3.7 7.6 11.4 8.3 8.7 6.6 1.1 35.5 7.0 4.3 2.2 1.4 3.2 10.2 6.2 3.8 3.3 2.8 0.6 4.4 13.4 36.0 7.1 3.2 10.3 5.4 3.4 2.6 33.4 20.6 1.7 17.4 30.4 1.9 5.1 2.9 20.3 10.7 4.9 7.5 1.2 1.3 1.9 1.9 1.6 1.3 7.0 4.1 8.1 4.0 5.8 4.2 13.7 22.2 38.7 6.1 4.6 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 4.8;REH: 4.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031510, HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA031510: AB_10603119, HPA031511: AB_2673915, HPA068559: " "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavourable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 6.4 8.2 3.8 4.3 6.5 2.9 4.0 9.9 6.3 5.7 6.6 5.5 4.2 2.2 6.0 5.5 5.3 3.5 5.3 3.6 5.0 3.5 3.9 6.6 4.1 2.5 4.3 7.5 5.7 12.4 4.7 4.6 6.3 4.0 6.2 2.7 5.6 2.9 6.7 6.1 6.8 2.6 5.9 3.7 7.0 6.3 7.9 4.2 2.6 4.7 4.1 3.8 4.4 4.2 2.1 2.7 0.4 3.8 0.9 1.1 0.5 0.0 0.3 0.0 1.1 2.9 1.7 0.0 2.3 0.3 0.5 1.1 0.0 1.9 1.5 0.6 1.2 2.0 0.0 0.6 0.9 4.8 0.9 3.6 0.9 0.2 1.4 3.7 0.0 1.5 0.1 0.8 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.6 0.0 4.4 2.4 1.1 0.0 0.0 1.0 0.9 0.3 0.6 0.2 1.7 0.0 0.0 0.0 1.1 1.1 0.0 0.1 2.3 0.1 1.9 0.6 0.1 0.0 3.8 0.1 0.6 1.4 0.7 2.1 0.9 0.1 2.7 1.0 1.1 0.5 0.4 0.9 1.4 1.5 0.1 0.5 3.8 6.5 9.9 6.3 5.0 3.5 4.3 7.5 4.0 4.2 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol 2800000 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavourable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favourable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 28.6 14.2 15.0 29.7 16.9 19.1 34.8 12.2 21.0 36.3 37.4 12.1 23.0 31.9 24.6 26.5 68.4 20.4 41.3 30.0 14.7 12.8 30.5 14.2 23.9 31.2 10.6 10.1 20.0 20.6 12.4 13.9 38.4 14.7 28.3 28.8 36.8 30.8 21.6 18.8 60.6 67.9 34.8 9.2 31.7 30.2 22.1 7.6 38.2 28.2 41.6 48.5 39.2 45.4 8.1 11.2 11.4 13.4 1.5 13.7 6.7 36.0 11.2 20.0 18.5 30.8 18.4 28.4 16.9 23.8 23.7 23.2 32.9 49.0 25.7 8.6 21.1 32.7 18.5 37.2 22.7 64.0 9.5 27.4 14.4 18.8 43.5 27.6 19.5 11.9 59.5 18.6 54.8 20.3 9.9 17.8 15.5 15.7 20.6 11.4 17.9 8.5 26.1 12.3 13.9 22.8 32.6 11.7 16.8 10.7 17.2 22.8 20.8 26.9 27.4 15.1 11.0 12.3 19.4 17.4 9.1 9.6 23.5 16.7 24.8 5.8 13.4 6.1 6.1 10.6 7.2 6.6 11.4 8.7 11.2 8.1 7.8 6.1 11.4 1.5 12.7 7.5 13.7 6.7 15.0 16.9 12.2 21.0 14.7 12.8 10.6 10.1 14.7 7.6 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492674-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 164.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 17.8 13.6 22.3 14.2 26.0 16.3 12.9 22.3 35.3 16.4 17.1 17.0 13.0 14.6 17.7 15.9 19.3 15.4 16.7 19.0 19.4 20.0 17.3 13.5 13.4 13.5 16.3 20.4 17.5 19.2 18.9 17.1 15.6 16.4 15.1 12.9 13.5 14.2 17.6 164.2 15.3 14.2 17.3 12.6 15.8 16.1 16.8 14.4 15.2 20.0 24.6 12.6 14.6 16.6 15.0 13.6 13.7 16.4 21.5 19.9 10.6 18.3 11.7 23.4 29.0 28.8 20.1 36.0 30.7 20.7 23.4 26.8 13.0 16.2 7.0 8.7 40.9 15.7 32.9 33.4 28.5 26.2 34.5 19.6 24.8 33.6 26.1 11.9 15.1 28.9 24.0 22.6 18.2 52.8 30.2 6.2 42.8 19.3 17.6 18.5 32.6 16.8 29.7 29.8 10.4 20.6 15.6 39.3 18.0 14.9 11.3 19.2 9.0 21.1 61.5 17.7 21.7 20.3 21.7 12.9 2.9 11.9 17.1 9.8 20.0 13.7 14.8 11.5 16.9 13.4 15.5 14.5 15.5 17.5 13.6 15.0 12.0 11.6 5.5 21.5 16.4 10.7 19.9 10.6 22.3 26.0 22.3 35.3 19.4 20.0 16.3 20.4 16.4 14.4 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023265-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: " "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavourable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 5.4 1.4 1.1 13.5 5.1 25.9 3.3 3.8 1.1 18.0 6.4 0.3 34.8 3.7 42.3 29.6 11.7 6.0 5.2 1.9 1.2 2.3 3.5 3.2 6.7 12.8 1.2 0.3 4.7 4.0 10.2 5.8 50.7 1.2 11.5 4.8 2.2 6.3 22.4 1.2 5.1 6.1 19.1 1.5 8.5 4.7 5.2 0.8 44.7 2.3 6.8 10.2 18.0 6.6 8.4 6.2 26.4 11.6 22.0 13.3 10.2 9.0 3.1 0.3 0.0 1.5 1.4 20.7 0.3 1.1 0.1 0.1 8.3 8.2 12.3 5.6 2.0 10.3 23.0 14.4 0.0 10.6 18.8 17.7 7.8 7.8 1.4 37.0 1.4 2.0 8.6 0.0 9.8 4.0 7.8 11.6 3.4 7.9 38.0 34.4 18.4 1.2 27.5 11.4 15.8 9.3 14.5 7.7 8.5 5.4 4.9 0.2 6.3 9.8 0.1 3.7 4.0 11.2 13.2 8.9 14.0 13.7 3.4 40.3 1.8 26.4 5.1 16.6 13.3 6.7 13.0 8.4 9.1 11.3 6.2 7.3 11.8 12.2 10.0 22.0 11.6 2.3 4.0 10.2 1.1 5.1 3.8 1.1 1.2 2.3 1.2 0.3 1.2 0.8 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98401403-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.3;granulocytes: 9.0;monocytes: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavourable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavourable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 16.5 16.6 6.5 8.1 12.4 2.5 20.5 2.6 10.6 17.2 13.1 10.5 14.2 4.6 22.2 13.1 9.0 16.0 12.6 10.0 7.4 4.1 14.7 12.0 16.2 10.8 12.8 3.6 22.8 10.7 15.1 18.9 53.1 9.9 15.0 6.0 8.2 10.8 16.4 11.6 10.0 10.8 23.5 12.9 8.2 9.5 10.1 11.4 3.4 10.6 7.9 5.9 16.4 24.3 1.9 8.3 9.0 8.7 1.8 1.8 2.9 37.6 7.1 7.5 9.9 24.4 12.2 7.5 13.1 11.8 12.3 10.7 5.2 16.0 0.0 11.4 13.0 15.3 5.2 11.3 19.9 9.0 6.7 10.1 3.5 3.5 8.3 3.3 8.8 8.1 19.5 6.3 17.2 5.2 4.2 5.5 8.9 4.7 8.4 4.0 2.2 2.8 7.4 6.5 3.2 14.0 4.7 1.9 4.4 8.3 9.6 8.1 7.9 5.5 3.9 8.3 5.3 12.5 7.2 4.4 6.5 2.7 7.4 4.2 13.1 2.1 8.6 4.5 1.3 8.7 1.4 1.9 0.8 1.8 8.3 1.3 1.1 0.7 9.0 1.8 5.4 3.4 0.1 2.9 6.5 12.4 2.6 10.6 7.4 4.1 12.8 3.6 9.9 11.4 STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710167-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 56.0" "Cell line enriched" "Detected in some" 8 "CACO-2: 19.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023194 Enhanced "HPA023194: AB_1857590" "unprognostic (4.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.42e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-6)" "unprognostic (7.83e-2)" "unprognostic (9.21e-3)" "unprognostic (1.46e-1)" "unprognostic (3.65e-1)" 0.1 0.0 0.1 0.1 0.7 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 56.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 19.7 2.4 0.0 2.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.1 0.2 0.0 0.1 0.1 0.1 0.1 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387852 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.7;brain: 21.1;retina: 31.9" "Group enriched" "Detected in some" 5 "RT4: 9.6;SK-MEL-30: 33.8" "Cancer enhanced" "Detected in many" "melanoma: 11.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040236 Uncertain Approved Centrosome Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 2.1 19.7 4.8 1.3 7.1 0.4 2.3 21.1 7.7 1.2 1.8 6.2 0.6 1.2 1.6 5.6 1.0 1.3 4.3 1.6 4.9 12.6 6.3 0.6 2.1 0.5 12.1 2.2 5.1 4.2 0.4 8.5 0.7 20.7 2.1 1.1 31.9 1.2 1.8 0.6 2.9 1.1 1.4 12.4 0.8 1.4 2.1 6.9 0.0 15.7 0.5 0.5 4.1 2.1 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.1 3.7 9.6 0.9 0.4 0.0 0.1 33.8 0.0 0.0 0.1 0.0 0.6 0.4 0.3 1.1 0.2 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 4.8 7.1 21.1 2.3 4.9 12.6 12.1 2.2 20.7 6.9 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051442-5500998 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.6;lymphoid tissue: 33.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 11.5;REH: 10.1;U-2197: 18.5;WM-115: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive B-cell: 1.3;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.3;dendritic cells: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA058536 Approved Vesicles,Microtubules Microtubules Vesicles "HPA058536: " "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favourable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 5.2 0.8 6.0 2.1 4.8 2.3 7.3 1.0 5.8 6.0 2.1 5.2 1.6 1.2 5.7 1.6 2.3 2.5 4.7 0.9 4.5 7.6 23.6 0.5 1.3 2.8 5.3 2.2 1.2 4.9 0.8 0.8 5.1 4.2 2.3 2.2 3.0 2.9 1.9 2.1 3.6 1.6 7.0 3.9 0.6 9.5 7.1 2.9 33.6 2.8 2.1 1.9 4.2 6.1 1.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.3 0.0 0.2 0.4 0.0 4.0 0.5 2.7 0.1 0.0 0.0 0.0 0.8 8.1 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 11.5 0.0 0.0 1.4 0.0 0.0 0.8 1.7 0.0 10.1 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 2.9 0.0 1.1 18.5 0.0 0.4 0.0 0.0 0.0 0.0 47.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.0 4.8 1.0 5.8 4.5 7.6 5.3 2.2 4.2 2.9 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017894 Uncertain "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavourable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavourable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 6.8 8.2 23.5 6.4 23.5 6.1 7.1 8.3 31.6 4.1 4.9 6.3 6.0 5.0 4.6 15.5 3.4 9.4 7.8 7.0 17.9 12.8 6.3 4.2 7.3 8.5 9.2 16.1 5.8 7.0 6.2 6.7 4.8 7.7 4.6 4.7 3.2 5.6 5.5 11.3 7.1 4.7 4.9 7.7 10.7 4.8 26.1 8.1 8.7 4.9 3.0 6.1 4.6 3.6 5.5 14.5 25.0 11.2 3.2 4.9 3.6 31.5 20.7 6.3 16.0 9.0 11.4 1.3 6.6 5.2 8.4 10.9 4.6 22.1 7.0 5.0 7.7 7.3 9.2 2.7 8.2 4.1 14.8 4.0 21.2 21.9 11.3 3.7 15.2 8.6 10.1 7.6 8.7 7.4 7.1 4.9 9.0 9.5 4.6 14.0 4.2 15.1 5.5 4.0 2.2 11.0 5.5 16.7 13.1 4.8 4.5 9.4 5.1 8.8 4.9 7.0 6.9 8.7 5.2 9.1 1.7 17.3 15.2 3.5 3.4 25.0 10.7 9.2 3.5 11.2 4.5 3.6 2.9 4.0 14.5 5.5 3.6 2.9 1.4 3.2 9.5 8.3 4.9 3.6 23.5 23.5 8.3 31.6 17.9 12.8 9.2 16.1 7.7 8.1 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell line enhanced" "Detected in many" "Daudi: 14.1;HEK 293: 12.0;Karpas-707: 13.2;SCLC-21H: 14.8;U-251 MG: 14.9;U-266/84: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: " "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favourable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.8 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.2 0.0 14.1 7.4 0.3 0.0 4.3 1.3 3.7 0.0 12.0 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 0.3 0.0 13.2 0.1 0.0 0.3 0.0 7.0 0.0 5.3 1.3 8.9 3.8 0.0 14.8 3.9 0.0 0.0 0.1 0.0 0.8 0.0 0.0 6.7 0.1 14.9 3.1 12.5 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101611-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 27.8;testis: 37.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA026452: , HPA051673: " "unprognostic (2.25e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (1.30e-2)" "unprognostic (3.25e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (9.46e-6)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-2)" "unprognostic (1.74e-1)" "unprognostic (4.67e-1)" "unprognostic (1.40e-1)" "unprognostic (4.99e-2)" 5.3 6.0 10.3 3.6 14.3 4.3 5.1 6.1 13.7 3.7 4.3 3.1 2.5 4.2 4.5 3.5 8.0 5.1 4.3 5.2 5.9 4.8 4.4 5.7 4.2 3.3 4.4 7.6 3.9 5.9 5.3 6.5 3.5 4.0 3.8 5.2 27.8 6.1 4.0 3.5 6.3 4.6 4.9 4.5 4.1 4.1 37.6 4.4 1.7 5.4 6.1 4.5 4.1 3.7 1.8 2.0 3.2 1.4 0.8 2.7 1.2 14.8 12.6 9.9 16.9 4.5 6.2 12.0 6.1 7.5 8.2 8.5 16.6 11.6 10.2 5.0 7.6 22.5 11.6 14.0 9.4 4.0 5.5 9.7 4.4 17.9 5.8 8.7 4.5 5.4 12.3 13.0 11.3 7.7 9.4 8.5 5.3 6.6 10.9 12.4 18.3 8.6 9.5 8.8 6.4 7.4 14.9 16.3 7.9 10.8 19.5 9.7 9.6 8.7 6.5 14.0 9.6 7.0 9.6 7.5 9.6 7.1 7.5 9.5 6.1 0.0 1.2 0.7 1.9 1.0 2.5 1.7 2.7 1.3 2.0 1.8 2.6 2.2 3.2 0.8 1.4 1.7 1.3 1.2 10.3 14.3 6.1 13.7 5.9 4.8 4.4 7.6 4.0 4.4 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672026-218702716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavourable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 4.8 10.0 7.5 4.7 11.4 2.0 6.4 7.9 11.1 9.1 7.4 7.0 11.9 4.1 14.4 13.3 5.0 13.9 9.8 3.3 6.3 3.5 10.1 4.4 6.9 3.9 2.3 6.6 13.6 9.7 12.3 23.2 3.9 7.6 9.5 6.3 9.3 7.3 8.3 3.3 4.6 5.8 7.8 5.5 4.9 7.9 63.2 4.2 3.5 11.4 3.7 5.0 9.3 7.1 1.8 1.6 3.2 1.9 2.2 1.6 1.7 2.7 6.4 14.0 11.9 15.2 11.9 8.5 7.6 6.1 9.7 9.2 8.3 4.6 3.7 10.6 7.9 5.6 9.5 7.9 8.6 1.6 7.9 3.6 19.1 11.4 7.4 5.0 6.1 12.8 5.9 9.5 6.8 7.2 8.3 4.7 8.0 6.4 3.0 6.3 8.4 4.1 5.6 6.0 3.7 11.9 14.0 11.4 9.7 5.9 9.6 3.9 9.8 4.1 6.9 13.5 5.0 5.1 5.2 6.0 4.6 1.9 8.4 2.4 5.6 0.0 1.9 3.2 1.5 1.2 0.9 1.8 1.1 1.3 1.6 0.6 1.1 1.6 0.2 2.2 1.4 1.3 1.0 1.7 7.5 11.4 7.9 11.1 6.3 3.5 2.3 6.6 7.6 4.2 STK38 NDR ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547470 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: " "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavourable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 19.1 8.4 12.4 39.8 10.0 19.4 32.8 18.8 12.7 16.0 26.3 7.8 14.9 17.0 18.8 16.4 28.1 14.6 18.3 15.3 12.1 7.0 15.0 17.3 21.7 45.9 11.9 6.4 12.3 9.5 7.8 11.0 15.4 9.0 17.0 27.1 11.3 24.8 18.7 14.9 21.8 29.1 28.1 13.1 25.1 16.4 24.4 11.0 34.3 10.6 13.4 28.5 22.4 19.8 10.6 13.1 33.2 30.5 25.8 27.6 22.4 17.6 13.0 13.8 14.8 27.9 21.3 12.0 19.7 16.0 20.5 20.7 10.0 12.1 23.7 15.3 29.3 18.9 11.4 8.2 24.3 9.7 9.8 17.0 16.9 9.0 13.8 6.4 9.4 14.0 21.6 15.9 10.2 12.8 13.8 13.9 29.2 10.6 10.3 16.7 5.7 11.6 40.2 16.7 6.3 19.4 22.2 16.1 7.6 24.0 11.1 13.8 11.8 16.9 12.3 16.7 14.8 13.3 12.7 11.7 20.7 16.7 3.8 25.0 16.0 33.2 19.8 15.0 27.6 22.6 21.5 10.6 22.9 24.1 13.1 8.1 20.5 22.3 27.1 25.8 30.5 6.6 21.4 22.4 12.4 10.0 18.8 12.7 12.1 7.0 11.9 6.4 9.0 11.0 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.3;granulocytes: 32.2;monocytes: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol Cytosol "HPA038623: AB_10967059, HPA051324: " "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 21.2 8.4 11.0 14.6 10.9 10.9 27.2 9.6 14.6 13.0 26.3 5.7 9.7 8.4 23.9 18.2 16.8 14.8 18.2 30.2 10.9 7.8 8.9 8.5 10.8 7.8 11.1 11.8 9.6 8.9 30.2 15.2 10.6 11.9 15.3 15.0 6.8 14.0 10.9 9.1 10.8 14.6 52.3 17.0 7.6 15.6 7.5 10.1 10.0 8.8 10.5 9.8 21.9 22.7 4.5 19.3 32.2 13.0 4.0 4.0 5.3 4.1 5.7 14.9 6.6 6.8 4.7 11.0 2.7 3.9 1.7 2.4 7.2 3.1 9.7 6.4 2.3 7.8 6.7 4.6 2.7 56.9 5.5 6.0 6.9 3.6 5.7 14.7 7.0 5.6 4.8 6.3 8.1 13.7 7.3 7.7 3.4 3.0 9.7 16.0 17.6 8.7 3.6 17.3 7.5 2.5 8.0 2.4 7.9 12.0 7.4 4.6 3.6 5.0 5.4 5.9 5.2 8.4 7.3 2.8 2.7 10.2 2.9 6.9 2.4 6.0 13.0 22.9 4.0 11.1 2.8 4.5 3.1 3.9 19.3 3.4 3.8 3.1 32.2 4.0 8.1 8.2 4.0 5.3 11.0 10.9 9.6 14.6 10.9 7.8 11.1 11.8 11.9 10.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168248141 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: , HPA062802: " "prognostic favourable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavourable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 6.2 2.1 8.4 4.6 11.0 1.3 3.5 9.3 14.1 4.3 9.1 8.3 1.7 10.5 2.3 4.7 14.1 1.9 5.9 7.6 9.8 7.4 2.9 0.8 2.4 7.3 12.3 9.7 3.2 9.9 5.0 8.2 1.2 14.2 9.9 11.7 7.1 22.8 3.8 2.2 3.4 6.1 4.3 19.0 2.5 11.2 35.5 5.5 7.2 2.2 1.8 8.0 5.6 5.3 0.7 1.0 0.0 0.7 1.9 3.4 0.5 6.6 4.0 15.2 4.8 9.4 13.8 1.5 16.7 12.3 11.2 10.4 0.0 21.6 18.3 4.6 10.8 17.3 9.7 12.2 14.1 5.8 6.0 7.6 4.4 13.5 17.4 10.2 0.8 9.5 17.3 13.3 13.9 7.6 0.1 0.0 23.4 3.8 17.7 3.6 10.5 8.5 25.4 6.0 1.5 8.4 16.5 22.5 9.5 5.8 0.8 6.8 3.0 7.5 7.1 13.6 4.2 9.6 10.9 0.0 0.0 14.7 10.3 9.1 9.1 0.0 0.7 0.0 2.5 0.4 1.3 0.7 1.9 3.4 1.0 0.7 0.4 2.0 0.0 1.9 0.3 0.3 3.3 0.5 8.4 11.0 9.3 14.1 9.8 7.4 12.3 9.7 14.2 5.5 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966474-45079959 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavourable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 9.5 8.8 10.4 24.5 11.5 39.5 8.1 7.5 13.4 7.8 8.6 10.3 5.4 8.1 9.3 6.5 8.9 7.3 9.4 6.1 9.3 8.8 6.3 7.4 18.8 30.6 10.5 9.1 8.3 6.4 5.9 9.3 8.2 7.7 7.5 10.6 7.4 9.3 8.7 4.2 11.4 16.1 8.2 12.0 29.1 9.6 7.4 9.6 32.3 8.0 4.9 36.6 11.5 8.7 10.8 6.9 40.6 13.3 10.3 14.5 7.9 11.6 7.9 10.1 7.2 6.2 7.8 7.0 10.3 15.8 17.5 15.9 22.4 6.4 28.6 9.0 7.3 12.4 10.7 13.8 22.5 12.8 5.7 20.8 11.6 15.7 10.9 26.7 29.6 6.3 11.4 16.4 17.9 6.4 9.6 16.5 8.8 9.2 19.9 18.1 6.2 5.4 12.9 11.2 13.3 6.4 8.0 4.8 5.9 15.3 8.9 11.7 8.1 16.9 8.2 13.2 12.9 15.2 11.9 21.6 16.9 31.8 12.9 12.8 9.7 24.4 7.6 20.5 14.5 7.7 14.4 10.3 13.8 13.3 6.9 10.8 14.3 11.9 40.6 10.3 13.3 3.9 13.3 7.9 10.4 11.5 7.5 13.4 9.3 8.8 10.5 9.1 7.7 9.6 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385896 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 19.2" "Group enriched" "Detected in all" 5 "granulocytes: 19.2;monocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favourable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 22.9 7.2 9.8 15.3 9.4 9.2 26.5 8.9 11.1 10.2 19.1 7.4 16.7 9.4 11.8 12.2 22.3 11.3 18.2 25.6 10.0 7.1 14.3 23.5 16.6 15.4 13.1 7.4 22.2 34.4 9.2 14.7 19.2 12.1 15.7 9.1 9.0 25.1 17.7 53.9 17.2 10.8 26.0 10.3 17.2 17.0 32.0 8.9 9.2 14.6 20.7 16.6 19.5 26.6 2.4 2.7 19.2 8.5 1.6 2.9 2.4 7.0 3.1 15.6 16.2 11.1 6.4 8.8 7.2 9.8 8.7 9.4 17.1 10.2 30.0 5.9 6.7 7.1 14.2 3.1 6.4 13.0 11.1 19.6 2.9 21.8 11.0 11.4 26.2 5.8 11.8 6.7 3.5 5.4 24.0 10.9 5.4 11.1 11.8 15.1 10.0 4.3 13.6 10.6 19.9 5.4 8.0 19.1 9.7 5.5 8.7 23.9 5.9 13.5 9.0 5.5 11.5 16.1 15.8 11.4 6.4 25.3 28.6 10.0 18.0 1.0 3.0 4.9 2.6 6.7 2.9 2.3 1.7 1.7 2.7 2.4 1.0 1.5 19.2 1.6 8.5 2.6 1.0 2.4 9.8 9.4 8.9 11.1 10.0 7.1 13.1 7.4 12.1 8.9 STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3A, catalytic subunit of the oligosaccharyltransferase complex" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 202.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved Uncertain Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favourable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavourable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavourable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" 20.6 20.5 8.3 13.1 11.7 8.3 16.9 10.7 13.9 27.8 19.3 17.7 39.6 12.0 30.5 41.4 19.6 20.8 15.1 19.5 8.3 9.1 26.2 67.1 18.7 14.9 9.3 7.7 30.1 59.0 202.3 27.5 35.9 11.6 22.2 17.4 20.8 50.7 41.4 9.5 12.9 19.8 17.1 12.3 21.8 17.7 17.1 6.7 19.2 38.6 13.6 20.8 19.5 18.0 15.0 53.2 27.0 15.5 17.2 27.5 13.4 20.7 18.9 24.2 33.2 45.6 35.4 26.0 38.0 45.4 31.0 38.8 57.5 56.2 27.1 46.2 55.9 38.4 33.5 33.3 41.2 21.1 17.8 63.8 13.1 39.7 50.5 38.1 29.9 27.3 24.2 42.8 83.7 34.5 26.8 40.6 39.0 15.3 15.3 12.2 15.5 20.6 18.2 20.6 40.7 33.8 32.3 15.1 13.0 26.9 44.0 13.5 51.5 27.5 30.8 44.6 16.1 18.8 29.8 12.8 14.9 20.9 17.2 38.6 35.4 27.0 15.5 11.6 19.7 14.8 27.5 15.0 19.1 18.2 21.6 11.6 13.8 16.0 5.4 17.2 13.0 53.2 14.1 13.4 8.3 11.7 10.7 13.9 8.3 9.1 9.3 7.7 11.6 6.7 STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3B, catalytic subunit of the oligosaccharyltransferase complex" Q8TCJ2 3 31532638-31637622 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" 9300 "Endoplasmic reticulum" "HPA036448: , HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favourable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" 23.0 30.3 16.0 27.5 16.7 21.7 27.4 15.4 19.4 28.4 25.0 16.9 37.0 18.6 28.4 37.9 28.8 22.4 29.0 27.5 15.1 15.6 28.2 64.1 30.1 36.9 16.5 15.5 62.3 39.4 36.2 20.3 85.9 16.5 26.3 25.1 22.3 25.2 26.3 31.2 19.2 29.2 23.2 19.7 29.4 22.9 36.7 13.6 60.2 44.3 23.4 30.3 27.5 27.7 3.6 7.7 8.4 5.3 8.4 8.5 3.0 16.3 27.5 25.3 26.5 31.9 32.3 55.4 30.7 27.0 23.0 26.7 25.0 35.6 28.5 15.1 27.8 13.9 23.4 26.6 30.2 80.2 15.4 24.4 28.0 26.6 24.6 52.5 29.1 24.7 28.6 32.7 41.4 23.2 13.1 45.7 31.3 9.2 51.4 32.5 20.4 15.5 53.8 13.7 41.3 26.8 23.7 10.8 13.2 30.4 45.2 17.8 20.4 28.1 45.1 31.1 19.9 30.7 27.0 28.8 34.5 23.9 28.2 36.2 25.5 2.3 4.6 8.4 4.7 5.3 7.5 3.4 8.5 6.5 4.0 3.6 8.2 6.5 1.7 8.4 3.7 7.7 4.1 3.0 16.0 16.7 15.4 19.4 15.1 15.6 16.5 15.5 16.5 13.6 STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favourable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" 29.4 43.7 52.2 20.1 43.2 19.3 40.5 39.1 53.3 25.1 24.8 18.1 27.6 24.1 19.7 34.9 35.2 31.1 25.5 45.2 43.2 38.6 24.0 25.9 23.6 28.1 42.0 42.5 29.4 43.4 39.8 27.2 12.1 35.0 23.4 17.7 18.6 37.7 29.7 92.5 33.7 20.9 24.5 34.5 19.7 22.8 13.8 25.4 13.1 29.1 30.2 19.4 22.3 35.9 18.0 21.0 19.4 14.5 10.3 16.9 6.9 17.8 24.2 16.4 27.7 37.5 34.4 9.4 24.4 28.7 29.0 25.8 30.1 22.8 18.1 17.3 40.8 15.3 20.2 36.7 12.1 19.9 66.8 11.2 35.0 25.1 54.1 18.9 22.4 40.8 39.4 33.9 21.5 29.3 18.1 30.3 44.8 70.7 20.5 18.6 18.3 26.5 31.7 10.7 44.5 38.7 17.9 28.6 23.2 19.5 43.0 30.6 27.4 36.3 23.2 26.6 23.3 22.0 29.3 30.0 31.0 29.2 21.0 17.2 30.0 11.9 14.5 19.4 16.9 11.9 15.4 18.0 14.6 14.7 11.7 17.3 13.6 12.9 14.0 10.3 12.4 21.0 12.2 6.9 52.2 43.2 39.1 53.3 43.2 38.6 42.0 42.5 35.0 25.4 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618939-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8;stomach 1: 16.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.2;HDLM-2: 10.8;HMC-1: 11.9;HUVEC TERT2: 16.4;TIME: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA040468: , HPA048569: " "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.6 0.3 2.6 2.3 10.6 1.0 3.8 0.1 13.4 2.2 14.4 0.7 0.5 2.1 0.5 1.1 8.9 1.9 6.2 0.1 1.8 1.6 0.5 0.3 1.2 2.4 1.8 4.2 0.4 0.3 0.0 8.4 3.4 2.1 10.6 15.8 0.0 7.8 2.6 0.2 2.6 10.3 0.6 0.6 1.0 16.0 0.3 0.7 0.0 0.4 0.6 2.8 4.3 3.6 0.0 0.0 0.4 0.0 12.5 1.9 0.2 2.9 0.1 0.0 0.4 0.0 0.0 0.9 4.8 0.5 2.2 2.1 1.6 18.2 0.2 3.1 1.2 0.8 0.9 5.0 4.8 10.8 0.3 0.7 1.3 0.1 0.0 1.4 11.9 0.2 0.2 3.4 0.2 16.4 0.2 0.2 5.2 1.7 0.1 0.8 2.7 1.3 0.0 1.4 0.2 1.6 9.4 0.6 0.0 2.7 2.9 0.0 2.3 0.3 15.2 0.6 2.5 0.3 0.6 0.0 0.6 0.1 2.1 0.1 3.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.4 12.5 0.0 0.0 0.0 0.2 2.6 10.6 0.1 13.4 1.8 1.6 1.8 4.2 2.1 0.7 SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40134977-40860763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.1;liver: 27.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 27.5;LHCN-M2: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026698, HPA026704, HPA026705" Enhanced "HPA026698: AB_10600191, HPA026704: AB_10600230, HPA026705: AB_10601003" "unprognostic (4.66e-3)" "unprognostic (3.45e-2)" "unprognostic (2.06e-2)" "unprognostic (3.32e-3)" "unprognostic (5.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-3)" "unprognostic (1.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.80e-1)" "unprognostic (5.27e-3)" "unprognostic (7.65e-2)" "prognostic favourable (3.93e-7)" "unprognostic (2.62e-2)" "unprognostic (3.38e-1)" "unprognostic (3.41e-3)" "prognostic unfavourable (2.53e-4)" 2.7 13.5 3.2 5.1 4.6 0.7 4.0 1.1 3.1 4.4 5.0 1.1 0.7 1.4 9.6 2.9 3.2 2.7 4.5 6.9 4.3 2.4 42.1 27.6 1.2 3.9 2.8 2.4 5.7 3.8 3.8 3.5 1.2 4.8 3.4 2.9 5.4 2.4 4.3 11.3 1.6 5.6 13.9 5.0 1.3 1.8 4.1 4.1 0.0 2.4 6.3 1.5 2.9 3.5 1.4 0.2 1.1 0.2 0.0 4.6 0.7 0.5 0.0 3.0 2.3 3.3 7.6 1.2 1.5 2.9 2.2 2.5 1.2 0.6 2.0 0.7 2.2 0.1 1.0 27.5 3.4 0.0 1.3 1.7 0.2 4.4 4.1 0.2 0.2 9.6 6.2 2.3 1.4 0.6 2.3 0.3 16.5 0.0 0.1 0.3 5.2 2.3 1.9 0.3 0.0 4.7 0.0 0.2 1.7 2.5 1.1 3.5 0.1 0.4 2.3 9.4 2.7 0.1 0.6 0.2 0.0 0.1 1.8 0.8 2.1 0.0 0.1 0.3 0.7 0.0 1.2 1.4 2.0 1.0 0.1 1.2 4.6 2.7 1.1 0.0 0.2 0.2 0.0 0.7 3.2 4.6 1.1 3.1 4.3 2.4 2.8 2.4 4.8 4.1 SULT1A1 "P-PST, STP, STP1" ENSG00000196502 "Sulfotransferase family 1A member 1" P50225 16 28605196-28623625 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.1" "Group enriched" "Detected in many" 4 "EFO-21: 41.4;Hep G2: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 50.6;intermediate monocyte: 39.2;myeloid DC: 22.9;neutrophil: 47.7;non-classical monocyte: 22.3" "Group enriched" "Detected in many" 26 "dendritic cells: 22.9;granulocytes: 47.7;monocytes: 50.6" "HPA049500, HPA051051" Supported 3700000 "HPA049500: , HPA051051: " "unprognostic (2.57e-2)" "unprognostic (2.80e-2)" "unprognostic (8.40e-2)" "unprognostic (1.30e-1)" "unprognostic (5.60e-3)" "unprognostic (7.63e-2)" "unprognostic (4.17e-2)" "prognostic favourable (7.02e-4)" "unprognostic (1.30e-1)" "unprognostic (2.40e-1)" "unprognostic (6.71e-2)" "unprognostic (2.07e-1)" "unprognostic (3.70e-3)" "unprognostic (1.49e-1)" "unprognostic (4.10e-2)" "unprognostic (7.39e-2)" "unprognostic (1.89e-2)" 10.2 36.1 12.0 7.2 15.4 9.3 5.7 15.8 19.8 4.6 21.4 4.5 15.5 54.2 3.7 14.4 3.1 6.6 5.4 9.7 14.7 10.4 11.0 98.1 26.7 8.4 9.2 14.9 3.5 9.6 6.7 10.0 5.6 10.3 3.7 17.5 12.2 11.5 22.5 4.9 1.4 41.1 5.2 6.3 23.2 7.2 5.1 4.6 4.0 13.4 2.6 3.7 6.3 2.2 0.3 22.9 47.7 50.6 0.9 1.5 19.3 1.5 0.6 0.8 2.7 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.3 10.3 0.2 41.4 0.0 0.6 0.8 2.8 0.0 0.3 7.3 2.8 3.1 82.0 4.9 0.0 3.2 0.2 0.2 0.0 0.0 0.7 1.1 1.3 0.8 9.7 0.2 2.2 0.7 0.0 3.0 0.3 5.4 0.7 0.8 2.5 0.2 0.7 13.4 0.3 8.0 7.9 5.4 0.2 2.0 0.2 0.1 3.2 1.9 0.4 0.7 15.1 0.0 4.9 50.6 0.9 0.6 39.2 0.7 0.3 0.6 0.5 22.9 0.1 0.9 0.6 47.7 0.9 22.3 1.7 1.5 19.3 12.0 15.4 15.8 19.8 14.7 10.4 9.2 14.9 10.3 4.6 SULT1A2 "HAST4, STP2" ENSG00000197165 "Sulfotransferase family 1A member 2" P50226 16 28591943-28597109 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.5;liver: 26.2;seminal vesicle: 24.2" "Cell line enhanced" "Detected in many" "BEWO: 6.7;EFO-21: 8.6;Hep G2: 31.9" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "classical monocyte: 10.2;intermediate monocyte: 7.0;myeloid DC: 3.5;neutrophil: 12.6;non-classical monocyte: 3.6" "Group enriched" "Detected in many" 16 "dendritic cells: 3.5;granulocytes: 12.6;monocytes: 10.2" "HPA049500, HPA051051" Supported "HPA049500: , HPA051051: " "unprognostic (4.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.53e-1)" "unprognostic (6.13e-2)" "unprognostic (5.35e-2)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (1.05e-1)" "unprognostic (2.49e-4)" "unprognostic (5.83e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (2.74e-1)" "unprognostic (2.98e-1)" "unprognostic (1.44e-1)" "unprognostic (8.52e-3)" 1.0 1.9 0.6 2.5 1.0 0.5 1.2 1.6 0.7 0.3 9.8 0.6 5.9 25.7 0.5 1.1 0.9 0.6 1.6 2.1 0.8 0.5 2.3 26.2 11.9 0.3 0.6 0.6 0.9 1.4 1.0 1.2 2.7 0.7 0.3 6.8 4.6 0.9 24.2 0.2 0.2 37.5 0.2 0.6 2.7 0.7 0.3 0.2 0.5 4.5 0.5 0.2 1.9 1.1 0.2 3.5 12.6 10.2 0.4 0.5 3.9 1.3 0.6 0.6 0.5 0.1 0.3 6.7 0.7 0.0 0.1 0.0 1.3 2.9 0.2 8.6 0.2 1.1 0.3 0.4 0.2 0.4 0.3 1.2 1.6 31.9 0.5 1.0 1.3 0.2 0.5 0.5 0.1 0.2 0.7 1.4 0.1 1.5 0.2 2.0 1.0 0.3 1.2 0.2 0.6 0.1 1.3 0.4 0.9 0.2 4.5 0.0 3.1 0.6 0.4 1.6 1.0 1.3 0.5 2.4 1.3 0.3 0.4 0.5 0.5 1.1 10.2 0.1 0.3 7.0 0.5 0.1 0.2 0.2 3.5 0.2 0.3 0.3 12.6 0.4 3.6 0.8 0.4 3.9 0.6 1.0 1.6 0.7 0.8 0.5 0.6 0.6 0.7 0.2 SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 27.8;intestine: 31.0" "Cell line enhanced" "Detected in all" "CAPAN-2: 39.2;Hep G2: 53.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "classical monocyte: 27.8;intermediate monocyte: 24.0;myeloid DC: 16.2;non-classical monocyte: 11.1" "Group enriched" "Detected in many" 11 "dendritic cells: 16.2;monocytes: 27.8" "HPA049500, HPA051051" Supported 3200000 "HPA049500: , HPA051051: " "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (1.98e-3)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (7.27e-2)" "unprognostic (2.09e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.18e-8)" "unprognostic (2.34e-2)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-5)" 1.4 3.8 5.6 4.3 4.9 7.5 2.5 14.0 6.3 2.1 6.7 31.0 2.5 4.5 4.0 3.7 2.0 1.7 5.6 5.2 6.6 10.1 3.8 3.2 4.3 2.9 4.3 8.1 8.0 3.0 5.8 6.1 5.3 5.2 1.5 5.6 17.9 4.0 3.4 5.7 2.7 2.1 6.4 5.8 3.6 2.4 1.5 16.2 1.4 27.8 0.4 2.0 11.2 4.8 10.1 10.0 7.0 9.2 5.3 13.5 5.4 4.5 5.4 6.1 4.3 39.2 4.9 28.4 5.1 12.7 10.4 4.2 5.3 4.5 7.5 3.9 13.8 53.7 3.8 3.3 9.2 7.4 6.8 5.9 2.1 6.2 1.2 31.0 3.7 14.9 2.6 20.5 5.9 5.9 10.9 4.0 9.0 7.0 4.4 4.0 5.2 1.4 15.9 2.3 6.0 7.3 2.3 10.6 5.2 7.8 3.1 9.2 8.6 3.0 3.8 5.7 6.3 1.4 27.8 0.1 2.0 24.0 0.3 1.5 0.3 0.6 16.2 0.3 0.3 0.3 0.4 0.4 11.1 0.2 0.3 11.2 SULT1A4 ENSG00000213648 "Sulfotransferase family 1A member 4" P0DMN0 16 29459889-29464976 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 16.7;intestine: 38.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 30.9;EFO-21: 25.6;HEL: 20.9;Hep G2: 67.7;Karpas-707: 40.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "classical monocyte: 11.3;intermediate monocyte: 16.7;myeloid DC: 11.3;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 16 "dendritic cells: 11.3;monocytes: 16.7" "HPA049500, HPA051051" Supported "HPA049500: , HPA051051: " "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" 2.7 0.7 3.3 2.0 1.6 0.9 2.0 4.3 2.6 3.0 8.1 38.8 1.2 0.0 0.3 1.7 1.6 1.7 2.8 1.6 2.8 1.7 3.4 2.9 1.5 0.9 0.6 0.0 1.8 2.4 2.2 7.6 1.8 0.0 0.7 5.2 25.9 2.7 1.1 3.3 3.2 1.1 3.4 2.1 0.1 1.0 0.6 11.3 0.8 16.7 0.2 0.6 2.4 4.0 4.0 1.2 0.1 0.1 1.4 1.7 0.4 0.7 0.1 0.1 2.3 30.9 0.2 25.6 0.2 4.4 1.7 0.4 0.1 1.5 2.3 20.9 2.7 67.7 0.6 0.7 2.9 0.0 0.0 2.0 0.0 4.8 4.2 40.4 0.1 2.0 0.4 3.1 0.9 0.7 1.7 0.6 1.1 2.9 2.8 0.9 2.2 0.0 6.2 0.0 1.3 0.0 8.4 0.8 0.4 1.2 0.7 1.7 13.7 0.4 1.9 3.7 0.2 0.2 11.3 0.0 0.6 16.7 0.1 0.6 0.3 0.1 11.3 0.5 0.3 0.1 0.8 0.2 5.0 0.2 0.3 2.4 SULT1C3 ENSG00000196228 "Sulfotransferase family 1C member 3" Q6IMI6 2 108247195-108265351 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "breast: 91.1" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;U-87 MG: 1.8" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (4.13e-1)" "unprognostic (6.64e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 91.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SULT1E1 "EST, STE" ENSG00000109193 "Sulfotransferase family 1E member 1" P49888 4 69841212-69860152 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.8;liver: 26.2;vagina: 15.8" "Group enriched" "Detected in some" 19 "HHSteC: 37.1;HSkMC: 16.8;hTCEpi: 14.0;HUVEC TERT2: 10.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 8 "pons and medulla: 3.3" "Cell type enhanced" "Detected in single" "neutrophil: 1.7" "Low lineage specificity" "Detected in single" "HPA028213, HPA028728, CAB047344" Enhanced Uncertain "Nuclear membrane,Cytosol" "Nuclear membrane, Cytosol" "CAB047344: , HPA028213: AB_10599848, HPA028728: AB_10601894" "unprognostic (5.60e-2)" "prognostic favourable (4.06e-4)" "unprognostic (2.48e-1)" "unprognostic (1.07e-3)" "unprognostic (2.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.22e-3)" "unprognostic (8.62e-2)" "unprognostic (6.48e-5)" "unprognostic (2.48e-1)" "unprognostic (4.11e-2)" "unprognostic (5.55e-2)" 0.1 9.8 0.1 0.1 0.3 0.1 1.1 0.1 0.4 13.1 8.9 0.5 0.1 19.8 0.4 3.7 0.4 0.1 1.2 0.1 0.1 0.0 1.5 26.2 2.0 0.1 0.3 0.3 0.2 0.1 0.0 0.4 0.1 3.3 1.0 0.1 0.3 4.7 0.3 0.1 10.9 37.8 0.5 0.3 0.1 1.3 0.4 0.1 0.6 0.2 0.1 1.0 0.4 15.8 0.6 0.2 1.7 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.1 0.0 0.0 16.8 14.0 0.0 0.4 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.6 0.2 0.1 1.7 0.3 0.3 0.2 0.0 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.3 0.3 3.3 0.1 SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870466-47886397 "Enzymes, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 211.7" "Group enriched" "Detected in some" 34 "Hep G2: 26.0;RT4: 17.7" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 5.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol 210000 Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" 0.1 46.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 11.4 1.1 1.1 8.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 211.7 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.2 0.6 0.0 0.1 0.1 3.9 0.1 0.0 42.7 0.1 0.1 0.1 2.8 0.7 0.1 0.1 0.2 0.1 0.1 0.6 0.2 1.3 1.0 5.3 0.8 2.3 1.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 26.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.3 0.2 0.0 17.7 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 5.3 0.8 0.7 0.9 0.4 0.6 0.7 1.0 0.6 0.3 1.3 1.3 1.0 3.1 2.3 0.4 1.0 0.6 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552075-48599425 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.8;lymphoid tissue: 78.6;tongue: 79.6" "Cell line enhanced" "Detected in some" "A549: 7.1;CAPAN-2: 34.1;MCF7: 20.9;T-47d: 17.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB033013, HPA041724, HPA043539" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "CAB033013: AB_661450, HPA041724: AB_2677638, HPA043539: AB_2678540" "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" 0.1 0.1 0.1 0.3 0.1 0.0 4.0 0.1 0.2 28.7 0.8 0.0 9.2 2.9 2.2 5.2 91.8 0.3 2.3 0.0 0.1 0.1 2.5 0.1 6.5 0.0 0.2 0.0 0.1 0.2 0.8 0.1 11.4 0.0 6.9 0.0 0.0 12.4 6.9 0.2 45.7 13.4 0.0 0.1 0.0 0.7 0.2 0.0 0.5 1.1 79.6 78.6 0.6 32.0 0.7 1.5 2.5 1.0 1.1 3.1 0.9 5.6 7.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 34.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.0 3.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 20.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 2.9 0.1 17.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.5 0.8 0.4 2.1 0.9 3.1 0.4 1.8 1.4 0.7 0.7 0.6 1.2 1.4 1.1 1.0 1.5 1.1 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 SULT6B1 ENSG00000138068 "Sulfotransferase family 6B member 1" Q6IMI4 2 37167820-37196598 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 2.4;fallopian tube: 2.0;testis: 7.1" "Cell line enriched" "Detected in some" 6 "WM-115: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 2.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (1.86e-1)" "unprognostic (8.98e-2)" 0.1 0.1 0.1 0.1 0.3 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 2.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.0 7.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709012 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (4.92e-2)" "prognostic favourable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 5.7 3.3 6.5 6.4 7.6 18.0 4.9 8.7 12.5 7.0 5.1 9.3 6.0 5.1 5.7 20.7 7.3 5.3 3.4 6.0 6.0 8.3 5.0 9.2 4.6 10.8 8.8 6.9 6.5 4.4 3.6 4.7 9.3 6.7 4.5 5.4 8.3 6.5 5.4 6.9 7.0 6.0 4.7 6.2 9.5 5.2 6.7 5.9 21.2 3.9 6.4 10.7 4.8 3.5 5.8 2.8 7.1 6.4 10.7 11.7 6.8 14.7 18.1 7.1 7.5 1.8 2.2 14.6 7.1 5.5 13.9 11.4 11.0 9.9 16.3 4.3 5.2 10.4 17.6 10.1 8.4 12.4 18.0 6.4 16.7 8.9 1.1 15.7 3.6 1.9 2.0 12.3 6.3 9.9 16.2 11.5 7.5 17.0 13.5 16.5 8.4 17.6 9.9 13.2 17.3 4.6 8.2 9.4 6.2 9.7 9.4 5.2 13.9 13.2 5.3 8.6 14.8 11.9 12.0 7.9 11.9 13.8 6.4 22.7 9.4 4.5 3.0 7.1 9.8 4.4 7.2 5.3 6.5 10.3 2.4 5.8 8.1 7.7 2.1 10.7 6.4 2.8 11.7 6.8 6.5 7.6 8.7 12.5 6.0 8.3 8.8 6.9 6.7 5.9 SUV39H2 "FLJ23414, KMT1B" ENSG00000152455 "Suppressor of variegation 3-9 homolog 2" Q9H5I1 10 14878820-14904315 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045901, HPA057554" Enhanced Approved Mitochondria Mitochondria "HPA045901: AB_10960702, HPA057554: " "prognostic unfavourable (5.55e-4)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-3)" "unprognostic (6.80e-2)" "unprognostic (1.23e-3)" "prognostic unfavourable (2.01e-6)" "unprognostic (1.06e-1)" "unprognostic (9.15e-2)" "unprognostic (3.59e-3)" "unprognostic (2.42e-1)" "unprognostic (4.13e-3)" "prognostic unfavourable (5.71e-5)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" "unprognostic (5.55e-2)" "unprognostic (1.39e-1)" 3.0 2.9 4.7 3.4 7.4 4.9 5.2 20.0 8.6 3.1 3.8 1.6 2.1 3.2 3.8 2.3 4.0 3.0 3.2 2.4 5.4 2.8 3.5 3.8 2.7 3.6 3.3 4.4 4.2 2.4 2.4 6.3 5.1 3.3 3.9 4.7 1.6 2.4 3.6 2.4 3.3 2.9 3.7 3.0 3.4 2.7 41.8 4.4 10.3 2.8 4.9 4.0 3.3 2.8 0.8 3.1 0.5 1.8 5.6 4.0 0.8 13.7 13.1 21.9 12.5 4.1 4.9 8.6 7.5 4.6 13.9 19.8 19.5 7.9 11.0 6.8 4.4 9.7 16.2 9.0 17.2 11.2 10.8 16.6 9.2 12.0 2.4 7.4 8.0 2.4 3.2 14.1 4.4 9.6 21.4 7.4 10.3 13.4 14.8 2.1 13.5 3.5 18.3 14.5 8.9 5.9 6.5 7.3 8.1 11.6 7.2 6.3 12.8 6.4 5.6 10.1 16.2 12.2 11.8 4.3 16.1 25.3 6.2 8.1 6.4 0.5 0.4 0.3 2.8 1.8 4.0 0.8 2.4 3.5 2.2 0.6 3.8 3.6 0.3 5.6 0.5 3.1 3.7 0.8 4.7 7.4 20.0 8.6 5.4 2.8 3.3 4.4 3.3 4.4 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.5" "Cell line enhanced" "Detected in many" "Daudi: 38.7;HEL: 22.3;HL-60: 30.8;HMC-1: 20.5;REH: 25.8;THP-1: 23.7;U-698: 18.3;U-937: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 21.4;eosinophil: 23.3;intermediate monocyte: 19.0;memory B-cell: 23.1;myeloid DC: 24.9;naive B-cell: 17.5;neutrophil: 32.8;NK-cell: 8.7;non-classical monocyte: 16.4;plasmacytoid DC: 18.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" 1000000 "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.2 3.3 6.0 38.1 9.6 18.2 6.7 1.1 4.5 3.7 10.3 6.7 1.5 12.3 2.3 6.7 16.2 6.9 6.6 5.5 7.2 3.2 8.6 2.5 13.7 36.4 9.1 2.5 2.1 8.9 25.9 3.1 5.0 6.1 4.1 8.3 2.8 8.9 1.8 1.4 8.3 22.2 3.5 11.3 38.5 7.4 5.5 7.9 30.5 18.1 7.8 32.2 8.6 7.5 23.1 24.9 32.8 21.4 8.7 0.1 10.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 38.7 1.1 0.0 6.0 0.8 3.2 0.0 0.0 5.3 22.3 0.0 0.0 0.0 30.8 20.5 0.0 4.4 0.0 0.4 0.0 0.6 3.1 0.0 4.7 0.0 13.5 0.2 0.0 25.8 0.0 10.6 0.8 5.8 2.0 1.8 0.0 2.7 0.0 2.5 23.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.3 0.0 21.7 0.0 1.4 21.4 23.3 0.1 19.0 0.1 23.1 0.0 0.0 24.9 17.5 0.0 0.0 32.8 8.7 16.4 18.5 0.0 10.2 6.0 9.6 1.1 4.5 7.2 3.2 9.1 2.5 6.1 7.9 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134533 "Enzymes, Predicted membrane proteins" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favourable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 13.8 20.8 11.0 33.0 15.3 13.8 14.9 13.3 19.3 15.1 14.2 21.0 20.2 13.2 16.0 21.1 14.4 16.1 15.3 12.9 11.3 10.0 16.4 78.0 14.2 28.9 18.2 8.7 17.1 68.1 24.4 21.0 20.9 14.4 15.0 15.4 13.3 48.9 22.6 16.7 14.4 19.6 13.6 12.8 27.1 18.3 14.4 14.9 10.3 23.5 8.0 42.2 13.3 12.6 17.5 13.0 11.6 5.4 2.2 5.5 3.8 8.5 10.9 6.6 8.9 16.8 9.6 6.5 8.8 9.1 11.3 8.0 5.9 14.9 48.0 12.1 11.3 13.2 7.1 8.9 9.4 7.4 5.4 7.5 12.7 13.2 20.4 11.3 13.7 12.2 16.2 9.9 22.5 7.3 9.4 24.6 6.6 12.6 4.9 8.2 7.1 7.6 8.4 5.5 19.3 7.1 8.4 4.3 8.8 8.2 20.3 14.2 15.1 7.4 6.9 7.9 5.2 14.0 5.9 49.2 34.0 55.5 10.6 5.8 8.8 11.6 5.4 9.3 5.5 3.3 5.0 15.4 3.9 5.1 3.1 17.5 2.9 3.0 5.2 2.2 3.2 13.0 3.6 3.8 11.0 15.3 13.3 19.3 11.3 10.0 18.2 8.7 14.4 14.9 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366239-71532374 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001075, CAB016283" Supported Enhanced Nucleoplasm Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favourable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 20.1 16.2 15.0 17.1 19.8 16.3 17.7 20.7 18.0 20.7 15.5 23.8 17.1 10.0 25.4 17.1 14.4 19.1 16.1 12.9 15.4 12.0 11.9 12.9 13.8 17.8 18.5 16.5 23.9 17.5 25.5 19.3 15.4 17.3 16.9 15.4 20.8 14.5 16.1 19.6 16.8 17.1 18.3 17.2 21.3 15.8 12.2 21.3 19.4 20.1 12.0 18.7 18.4 15.8 5.0 4.7 5.2 4.8 4.2 4.9 1.8 11.2 9.8 11.2 7.5 9.0 15.6 7.0 8.4 7.8 8.9 7.4 7.3 6.8 10.5 7.2 9.4 10.7 15.6 6.7 11.4 6.9 13.7 12.5 12.9 7.2 6.5 23.7 12.1 9.1 6.8 9.5 18.0 9.2 17.0 25.5 9.0 7.9 13.1 10.5 12.9 12.9 12.1 22.8 12.8 6.0 14.6 5.9 9.2 23.4 8.2 10.4 6.0 12.6 11.6 10.5 8.8 8.4 5.8 10.9 10.1 13.6 5.8 19.1 7.8 4.4 4.1 1.1 4.4 2.8 3.8 3.0 4.6 4.5 4.7 5.0 4.4 4.9 5.2 4.2 4.8 3.5 3.1 1.8 15.0 19.8 20.7 18.0 15.4 12.0 18.5 16.5 17.3 21.3 TALDO1 ENSG00000177156 "Transaldolase 1" P37837 11 747329-765024 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pentose shunt" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 204.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 148.6;neutrophil: 204.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048089 Approved Nucleoplasm,Cytosol 39000000 Nucleoplasm Cytosol "HPA048089: AB_2680260" "unprognostic (5.29e-2)" "unprognostic (1.78e-2)" "unprognostic (3.47e-1)" "unprognostic (9.65e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (9.78e-2)" "unprognostic (4.27e-2)" "unprognostic (1.74e-1)" "unprognostic (7.97e-3)" "unprognostic (2.94e-1)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.16e-3)" 39.0 24.2 26.6 34.8 31.3 117.4 44.2 20.6 38.3 27.7 28.5 51.2 18.8 34.2 20.4 20.7 90.0 23.2 33.2 37.5 29.2 23.6 45.8 48.4 37.9 60.0 46.5 26.6 23.4 31.9 14.6 15.8 34.3 30.7 28.3 23.7 15.5 38.3 19.5 31.2 38.4 29.4 40.4 47.5 45.6 35.8 14.8 33.0 34.1 42.2 82.4 43.1 51.4 37.5 8.5 36.1 204.6 60.8 5.9 10.4 45.3 41.9 53.1 15.4 29.1 31.9 18.6 45.4 31.9 41.1 31.6 26.1 22.6 91.6 23.4 43.4 41.8 45.4 24.3 34.4 16.5 30.6 49.3 40.5 20.6 78.8 34.1 64.7 60.5 15.2 27.8 21.2 17.2 43.4 52.5 39.2 29.3 40.1 37.6 76.8 24.2 43.1 31.4 18.1 83.9 57.4 24.5 38.0 13.3 29.7 61.5 30.9 29.2 49.3 57.6 14.5 13.6 11.4 29.9 16.6 16.1 27.8 32.1 56.6 58.4 64.7 60.8 148.6 5.6 23.2 6.1 8.5 7.5 6.8 36.1 6.8 6.1 5.7 204.6 5.9 23.2 14.8 10.4 45.3 26.6 31.3 20.6 38.3 29.2 23.6 46.5 26.6 30.7 33.0 TAMM41 "C3orf31, DKFZp434E0519, MGC16471" ENSG00000144559 "TAM41 mitochondrial translocator assembly and maintenance homolog" Q96BW9 3 11790442-11846919 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036834, HPA044861" Uncertain Approved Cytosol Cytosol "HPA036834: AB_10672270, HPA044861: " "unprognostic (2.40e-2)" "unprognostic (4.41e-2)" "prognostic favourable (1.23e-4)" "unprognostic (4.45e-2)" "unprognostic (1.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.33e-3)" "unprognostic (3.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-1)" "unprognostic (7.34e-2)" "unprognostic (3.59e-3)" 13.9 12.9 21.8 15.9 27.5 9.1 15.7 25.6 19.8 12.5 12.2 14.2 12.5 11.5 17.7 23.7 15.2 12.4 10.0 13.8 13.9 11.5 12.4 12.0 18.7 25.0 11.3 15.3 21.7 12.9 12.5 15.4 9.9 11.4 10.7 12.0 11.2 11.7 14.2 15.2 17.3 10.4 15.0 13.7 12.3 10.1 14.1 14.8 12.7 10.8 8.4 17.4 13.8 13.8 8.7 8.9 7.7 7.1 7.1 11.3 5.0 4.1 7.9 9.6 6.6 10.4 13.2 17.8 6.5 4.6 9.9 9.9 9.4 6.9 16.0 9.5 6.7 5.2 16.0 9.7 12.9 5.9 15.2 9.5 7.6 10.9 12.2 17.4 5.1 7.5 14.4 9.3 10.5 15.3 13.9 4.9 12.6 12.1 9.8 13.0 7.7 16.8 9.8 5.5 14.1 15.1 10.3 4.4 3.8 5.6 7.3 10.7 9.5 7.9 4.0 5.2 5.9 15.5 9.2 3.8 9.4 8.3 6.3 14.9 4.7 2.2 5.3 7.7 7.2 3.6 9.2 8.7 11.3 7.0 8.9 8.0 10.4 10.6 0.2 7.1 7.1 6.6 8.7 5.0 21.8 27.5 25.6 19.8 13.9 11.5 11.3 15.3 11.4 14.8 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390464-29551904 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Approved Vesicles 13000 Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 17.2 11.5 19.1 11.9 25.0 12.7 13.3 20.1 24.4 15.8 11.9 22.2 7.9 7.1 14.9 10.8 12.7 11.0 11.6 15.3 18.7 15.5 13.6 10.6 13.2 11.1 30.0 17.6 13.5 9.3 31.7 13.7 14.3 21.8 12.0 10.7 10.9 11.1 13.3 15.0 13.8 9.8 17.7 21.0 13.0 10.8 14.3 23.5 11.7 17.7 6.0 11.2 14.5 17.1 2.4 4.8 5.5 2.1 1.4 3.0 0.9 13.6 24.3 19.2 8.2 14.3 18.1 8.1 12.9 13.8 11.9 12.5 13.1 4.8 8.5 12.7 21.0 10.7 17.5 8.9 21.4 17.6 12.9 13.5 14.1 7.0 10.4 14.9 12.5 11.9 11.5 17.5 18.0 16.2 13.8 7.7 15.5 9.1 11.7 5.5 8.1 6.2 10.9 27.1 5.9 11.2 19.7 10.6 13.0 22.2 20.8 13.4 15.0 13.8 23.5 18.2 14.8 15.9 18.0 7.1 15.3 9.8 13.3 9.4 16.4 1.7 1.9 1.5 2.0 2.1 1.6 1.6 2.0 2.4 1.7 2.4 3.0 2.2 5.5 1.4 1.9 4.8 1.2 0.9 19.1 25.0 20.1 22.7 18.7 15.5 30.0 17.6 21.8 23.5 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973641-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.51e-4)" "prognostic favourable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favourable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favourable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 27.8 24.1 26.2 15.1 26.7 12.3 17.7 29.2 30.6 13.5 13.6 21.5 11.8 18.5 16.8 13.0 12.4 14.1 15.1 17.6 25.0 18.2 13.9 10.4 23.0 14.4 22.1 22.7 15.8 16.3 26.2 18.7 22.5 20.7 13.6 9.6 15.0 17.1 15.9 22.8 20.0 19.3 14.8 14.9 26.3 16.0 21.2 20.2 14.0 15.9 9.8 11.5 12.8 18.0 2.6 3.3 4.8 2.8 2.0 3.2 2.0 11.2 21.5 11.8 18.5 13.8 9.3 18.1 20.6 11.0 14.0 13.1 17.2 15.0 12.2 17.5 14.8 17.5 10.7 10.4 7.5 18.9 22.7 13.1 21.7 17.2 10.1 12.8 25.2 10.9 9.0 14.8 6.0 23.3 11.7 12.4 13.3 20.7 14.9 18.3 11.4 14.5 27.7 17.1 11.3 8.8 10.6 13.9 11.1 11.8 15.8 6.1 19.8 14.6 32.5 24.1 11.2 17.1 11.9 18.1 11.6 11.5 14.8 14.8 17.5 1.3 2.8 1.5 2.9 2.7 3.1 2.0 2.9 2.6 1.8 2.6 1.6 1.4 4.8 2.0 1.4 3.3 3.2 2.0 26.2 26.7 29.2 30.6 25.0 18.2 22.1 22.7 20.7 20.2 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372945 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 14.6 16.2 31.9 24.1 31.0 30.8 14.6 44.3 33.5 11.6 21.2 17.2 10.3 23.1 15.2 11.4 16.0 9.8 16.9 15.1 27.8 31.7 14.0 15.3 19.4 26.3 25.7 20.8 17.5 10.9 20.2 23.6 11.9 20.7 25.6 21.3 12.0 13.6 14.6 18.5 17.0 31.6 15.3 23.7 24.2 20.9 8.9 28.6 28.3 18.1 9.9 26.9 18.5 18.3 20.9 22.4 38.2 37.8 36.4 27.8 17.1 8.2 5.7 4.3 3.7 10.5 12.8 4.9 8.6 9.8 5.0 6.6 2.9 12.8 25.2 2.8 11.5 7.4 3.7 7.7 7.9 9.1 3.2 29.7 2.9 3.7 12.3 30.4 41.9 8.7 9.3 15.9 23.3 16.1 17.2 3.0 9.2 5.8 16.0 20.0 1.6 3.0 9.4 5.8 2.6 4.7 14.3 0.8 4.2 8.0 3.6 11.0 7.4 22.8 24.9 8.7 1.5 8.1 7.4 2.9 2.8 19.9 12.3 21.0 11.6 38.2 17.0 37.6 27.8 23.3 26.2 20.9 21.2 24.1 22.4 19.3 18.8 24.5 37.7 36.4 37.8 20.9 19.3 17.1 31.9 31.0 44.3 33.5 27.8 31.7 25.7 20.8 20.7 28.6 TAT ENSG00000198650 "Tyrosine aminotransferase" P17735 16 71565660-71577130 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Aminotransferase, Transferase" "Disease mutation, Mental retardation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "liver: 387.0" "Group enriched" "Detected in some" 5 "Daudi: 2.3;Hep G2: 7.1" "Cancer enriched" "Detected in some" 10 "liver cancer: 152.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (3.66e-3)" "unprognostic (1.29e-1)" "unprognostic (8.17e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.01e-2)" "prognostic favourable (6.51e-4)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (2.27e-1)" "unprognostic (3.73e-3)" "unprognostic (1.88e-1)" "unprognostic (1.27e-4)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 387.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.9 2.6 1.5 0.4 0.2 0.5 0.2 0.1 0.2 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.2 7.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.2 0.4 0.1 0.0 0.7 0.9 0.0 0.1 0.3 0.1 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.5 0.2 0.5 0.0 0.3 0.2 1.5 0.4 0.2 0.3 0.1 0.4 1.2 0.5 0.4 0.2 1.9 0.5 0.5 1.5 0.2 0.1 2.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64451880-64502108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease mutation, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA045797: , HPA060211: " "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavourable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavourable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 19.1 23.3 13.7 16.8 17.1 32.3 19.1 17.8 20.5 14.9 18.3 10.0 14.1 18.0 17.0 15.1 15.3 13.8 15.6 11.7 14.7 15.6 15.4 20.8 17.8 18.3 20.2 13.6 15.6 11.1 13.1 27.2 40.6 21.1 16.3 12.9 10.1 15.0 18.3 24.8 12.1 21.4 17.2 18.8 24.6 14.5 27.9 16.9 3.4 13.3 12.6 16.7 18.4 19.6 9.7 8.2 22.5 11.9 16.3 11.8 5.9 13.4 15.5 8.8 12.9 15.8 16.0 19.5 14.8 21.5 13.9 13.3 8.7 8.2 18.9 12.9 16.0 12.7 11.4 12.4 16.5 17.3 10.8 20.2 11.2 12.0 17.4 20.6 25.3 12.0 11.4 13.9 13.4 18.5 15.5 27.5 17.9 16.5 0.6 16.2 17.7 9.1 9.6 9.8 18.2 15.2 24.5 7.4 10.7 19.5 20.0 14.3 20.5 15.0 17.1 12.6 12.2 10.1 14.4 17.4 30.3 18.4 15.9 11.4 16.2 22.5 7.3 16.6 11.0 11.9 11.8 9.7 8.0 11.0 8.2 7.6 2.8 7.1 15.1 16.3 10.6 1.9 9.5 5.9 13.7 17.1 17.8 20.5 14.7 15.6 20.2 13.6 21.1 16.9 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269864 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.4;HMC-1: 16.4;U-266/70: 16.3;U-266/84: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 13.3;eosinophil: 11.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: " "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favourable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 3.9 4.5 0.8 7.2 1.1 9.8 5.1 0.6 2.0 3.4 4.8 0.5 8.4 2.8 3.0 21.6 9.5 3.6 2.1 3.3 0.9 0.9 4.0 5.7 6.4 7.0 1.5 0.3 2.9 2.9 2.6 6.4 2.0 3.2 2.0 2.5 3.0 6.8 4.7 2.1 8.1 6.5 3.0 1.2 6.7 2.2 5.5 0.6 4.4 4.4 5.8 11.1 3.2 6.5 0.9 1.3 13.3 0.6 2.9 0.4 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.4 1.8 1.0 2.2 0.0 1.7 1.5 1.6 0.0 0.5 0.9 0.0 1.5 0.1 0.7 10.4 0.7 0.1 0.0 1.7 16.4 0.0 0.2 1.4 0.0 0.0 5.7 0.4 3.2 0.7 1.0 3.7 0.3 0.7 2.4 2.2 0.0 2.8 0.7 0.0 0.2 0.5 0.2 0.4 0.6 3.3 0.0 0.0 0.0 2.2 0.0 16.3 11.6 2.1 0.0 2.3 0.1 13.3 0.5 11.0 0.1 0.6 0.3 0.9 0.1 0.4 1.3 0.6 0.4 0.4 0.4 2.9 0.1 0.1 0.0 0.3 0.8 1.1 0.6 2.0 0.9 0.9 1.5 0.3 3.2 0.6 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230175 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 35.8;NTERA-2: 17.8;TIME: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 2.2" "Lineage enhanced" "Detected in single" "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" 7750000 8300000 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: " "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favourable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favourable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 28.6 7.8 8.1 4.6 5.9 0.4 17.9 3.4 5.4 10.8 4.7 4.6 3.4 3.2 14.5 5.3 6.7 5.9 9.1 13.0 7.1 6.1 25.4 8.7 27.8 2.9 6.9 3.4 6.1 4.5 3.5 4.0 36.3 6.9 5.4 4.7 12.4 3.4 5.5 7.8 3.0 5.3 10.6 5.3 23.4 4.0 3.7 3.5 0.3 9.7 8.4 2.4 6.4 12.4 0.0 0.1 2.2 0.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.2 2.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.0 0.0 0.6 0.0 0.0 0.7 0.0 0.8 0.3 35.8 0.0 0.0 0.3 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 38.8 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 8.1 5.9 3.4 5.4 7.1 6.1 6.9 3.4 6.9 3.5 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295069 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.4;lymphoid tissue: 12.0;testis: 5.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 61.2;fHDF/TERT166: 58.1;HBEC3-KT: 118.1;hTEC/SVTERT24-B: 74.6;LHCN-M2: 33.7;TIME: 96.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: , HPA065897: " "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 7.1 0.9 3.4 0.0 0.0 0.2 0.1 1.1 0.0 0.0 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 1.0 0.4 5.0 0.0 12.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 30.6 61.2 0.5 0.0 23.3 4.2 7.9 0.1 0.1 0.7 0.0 58.1 0.0 0.2 118.1 5.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.0 3.0 74.6 0.8 0.2 0.6 0.1 33.7 0.0 0.2 1.6 0.4 0.2 0.8 0.0 0.8 3.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 96.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 TESK1 ENSG00000107140 "Testis-specific kinase 1" Q15569 9 35605305-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 30.9 19.4 13.5 10.8 20.5 5.6 25.4 13.4 26.4 14.3 15.2 15.0 9.7 13.7 15.3 13.4 11.0 12.0 13.0 12.8 13.7 13.1 10.5 10.0 11.5 10.7 14.1 10.3 17.0 16.0 13.1 15.7 12.3 12.6 15.1 8.8 14.2 14.6 21.0 47.2 13.7 12.7 16.9 7.3 11.0 12.9 28.4 12.9 9.2 13.0 12.3 9.0 16.6 20.9 1.0 2.3 0.3 1.8 2.1 4.9 1.5 9.9 9.3 6.4 10.6 25.7 10.7 7.3 11.4 10.2 10.6 6.8 5.4 2.8 18.1 6.5 11.4 3.4 4.0 8.2 2.0 11.6 5.4 2.6 8.8 4.7 15.0 2.2 8.7 10.4 13.0 8.3 11.4 7.4 3.0 6.5 10.5 11.0 5.0 11.0 3.9 10.9 7.8 3.9 4.2 7.8 4.6 5.2 6.4 6.5 7.9 4.8 9.4 3.3 6.4 23.6 10.1 16.9 6.8 4.0 5.6 6.7 17.1 2.6 5.3 0.0 1.8 0.3 3.4 0.4 3.0 0.8 1.4 4.9 2.1 1.0 1.5 1.6 0.0 2.1 0.8 2.3 0.3 1.5 13.5 20.5 13.4 26.4 13.7 13.1 14.1 10.3 12.6 12.9 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.0;RT4: 12.7;SK-MEL-30: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027257: AB_10602477, HPA063869: " "unprognostic (2.95e-1)" "prognostic favourable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.0 0.6 4.3 1.9 3.2 3.6 1.5 5.2 0.6 1.5 2.0 3.4 2.7 1.5 3.7 4.3 3.5 1.8 2.7 1.7 1.2 9.8 1.8 2.9 2.1 3.0 1.5 0.6 10.9 1.2 0.6 3.0 2.4 3.4 1.5 4.4 0.1 1.4 1.7 12.7 0.3 1.4 3.3 6.4 12.1 9.9 1.5 0.0 0.2 2.0 1.6 1.1 7.1 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: " "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 11.1 6.9 10.3 11.5 14.6 20.0 15.4 12.6 11.3 14.4 20.0 11.0 5.5 7.4 18.8 8.0 13.2 10.9 14.9 9.7 7.8 7.5 16.0 9.8 19.2 18.9 15.8 4.3 13.3 8.8 6.5 13.5 50.9 14.1 12.3 9.2 10.4 10.2 12.2 8.4 6.6 11.0 28.6 17.9 13.9 25.5 11.4 12.4 10.8 7.7 8.1 11.5 13.0 10.2 1.6 2.0 13.1 2.4 4.0 8.3 1.9 3.3 5.0 30.8 9.5 7.2 5.3 4.6 11.5 12.6 10.7 12.1 5.1 2.4 7.5 3.6 9.0 8.0 10.4 8.9 14.6 19.5 3.2 11.2 5.6 4.5 11.9 6.9 27.3 11.0 9.6 16.8 7.9 1.9 15.5 3.2 14.7 5.2 1.0 7.8 6.5 3.0 2.8 67.2 3.2 2.6 0.8 8.3 9.7 8.9 39.9 11.9 7.4 9.4 3.5 8.0 6.9 34.3 7.0 3.2 3.2 5.1 16.8 11.9 6.9 13.1 2.4 9.1 8.3 1.6 7.2 1.6 3.6 6.1 2.0 1.3 3.5 6.7 4.9 4.0 1.9 1.4 2.2 1.9 10.3 14.6 12.6 11.3 7.8 7.5 15.8 4.3 14.1 12.4 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.4 14.4 0.9 0.0 53.4 80.5 2.4 12.5 17.6 4.3 4.3 3.2 13.3 0.3 45.3 16.8 5.0 0.6 18.3 7.2 1.0 1.3 1.4 1.6 16.2 22.8 2.2 11.8 69.5 16.3 18.6 18.0 46.7 0.2 0.0 65.8 0.2 2.3 1.6 0.4 5.8 2.0 5.8 0.3 23.2 5.8 0.0 0.9 3.7 1.0 3.5 0.0 2.4 60.3 21.2 5.2 9.6 4.7 0.4 0.0 2.0 12.7 2.5 8.5 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 106.0;lymphoid tissue: 70.0;tongue: 86.8" "Cell line enhanced" "Detected in many" "BEWO: 12.8;HaCaT: 17.6;HeLa: 11.5;MCF7: 12.6;SK-BR-3: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 78.3" "Region enriched" "Detected in single" 11 "cerebellum: 3.0" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171" Enhanced 430000 "CAB015159: AB_2202870, HPA040171: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 2.9 0.2 0.2 0.4 0.2 0.2 0.7 3.0 0.3 10.1 1.0 0.2 0.2 0.3 0.5 2.0 106.0 1.3 0.2 0.6 0.2 0.0 0.6 0.3 0.9 0.4 0.2 0.2 0.7 1.3 0.2 0.2 0.9 0.2 0.5 0.3 0.4 12.8 1.4 0.7 9.3 0.3 0.2 0.2 0.4 0.2 0.4 0.2 0.5 0.4 86.8 70.0 0.4 17.2 0.4 0.5 0.0 0.5 0.0 1.1 0.2 0.8 1.5 0.8 0.7 0.0 0.6 12.8 0.3 0.2 0.7 1.2 0.9 1.3 0.7 1.7 0.9 17.6 2.1 1.4 0.5 1.4 2.4 1.0 11.5 4.0 0.6 0.6 1.1 1.1 7.0 0.4 1.5 0.5 0.7 0.7 0.5 12.6 0.5 1.3 0.2 1.6 0.8 0.1 0.8 0.5 1.5 0.9 1.1 0.2 15.7 0.0 1.1 0.8 0.6 0.8 3.7 1.5 0.6 1.1 1.2 0.2 0.3 1.5 0.9 0.0 0.5 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.2 0.2 3.0 0.2 0.2 0.0 0.2 0.2 0.2 0.2 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127387-38166578 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 187.6;placenta: 212.7" "Group enriched" "Detected in many" 4 "CAPAN-2: 160.1;EFO-21: 53.8;HUVEC TERT2: 72.7;TIME: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 2.5;memory B-cell: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 23 "B-cells: 1.9;dendritic cells: 2.4;monocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" 1700000 Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavourable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavourable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 33.3 9.5 6.0 18.3 8.1 1.0 7.7 4.3 7.5 94.3 12.6 4.0 4.7 8.4 54.6 21.7 15.8 58.7 62.8 77.1 7.5 3.4 25.3 187.6 61.2 16.4 6.9 3.0 18.7 5.0 5.2 25.6 212.7 8.5 33.6 6.3 57.4 1.9 17.1 19.3 0.7 12.8 43.9 5.7 20.4 13.6 7.4 6.4 0.8 17.0 3.4 3.1 38.2 21.6 1.9 2.4 0.0 2.5 0.0 0.0 0.2 6.5 4.9 0.0 0.1 5.1 0.5 2.5 9.9 4.8 0.0 0.1 8.0 160.1 0.0 53.8 0.1 0.1 0.0 23.2 0.3 0.0 0.0 1.0 0.2 3.5 20.9 0.0 0.0 0.5 0.0 4.2 0.0 72.7 2.1 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 7.2 0.0 0.0 0.1 23.2 0.0 0.8 0.2 0.0 94.8 0.1 6.0 0.7 4.7 0.0 0.0 0.0 6.5 0.0 1.9 0.0 0.2 0.0 0.0 2.5 0.0 1.9 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 8.1 4.3 7.5 7.5 3.4 6.9 3.0 8.5 6.4 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341078 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 195.0;lymphoid tissue: 152.6;tongue: 206.5" "Cell line enriched" "Detected in some" 6 "EFO-21: 11.6" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 205 "neutrophil: 20.4" "Lineage enriched" "Detected in single" 205 "granulocytes: 20.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA004728 Enhanced 14000000 "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.1 0.1 195.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 24.5 0.0 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 206.5 152.6 0.0 2.8 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "prostate: 107.8" "Cell line enhanced" "Detected in some" "BEWO: 9.5;hTERT-HME1: 2.6;NB-4: 5.1;RPMI-8226: 3.6;SH-SY5Y: 2.8" "Cancer enriched" "Detected in single" 312 "prostate cancer: 75.4" "Region enriched" "Detected in single" 254 "cerebral cortex: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA032072, CAB033571" Enhanced "CAB033571: AB_2287329, HPA032072: AB_10603350" "unprognostic (4.40e-2)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.65e-1)" "unprognostic (8.56e-3)" "unprognostic (5.08e-2)" "unprognostic (1.44e-8)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.68e-1)" "unprognostic (6.41e-2)" 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 25.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.1 2.6 0.3 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.7 0.7 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 TGM5 TGX ENSG00000104055 "Transglutaminase 5" O43548 15 43232595-43266857 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 9.7;lymphoid tissue: 10.4;skin 1: 24.3;tongue: 13.1" "Cell line enriched" "Detected in some" 7 "HEL: 19.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "cerebellum: 2.9" "Not detected" "Not detected" "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.3 0.0 0.1 0.1 0.1 0.2 2.1 0.1 0.1 2.6 0.1 0.1 0.1 0.0 0.7 0.1 9.7 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.6 0.0 0.1 2.8 3.4 0.1 24.3 0.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 13.1 10.4 0.8 4.7 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.4 0.0 0.7 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TGM6 "dJ734P14.3, SCA35, TGM3L, TGY" ENSG00000166948 "Transglutaminase 6" O95932 20 2380908-2432753 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "lymphoid tissue: 5.7;skin 1: 3.3;tongue: 4.2" "Cell line enriched" "Detected in single" 12 "SCLC-21H: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 34 "cerebellum: 1.8" HPA059196 Uncertain "HPA059196: " "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.2 5.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276280-43302255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.9;testis: 2.9" "Cell line enriched" "Detected in single" 78 "EFO-21: 8.9" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 5.9 0.0 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 THG1L "FLJ11601, FLJ20546, hTHG1, ICF45, IHG-1" ENSG00000113272 "TRNA-histidine guanylyltransferase 1 like" Q9NWX6 5 157731197-157741448 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035877, HPA035878" Approved "HPA035877: AB_10669979, HPA035878: AB_10672993" "unprognostic (4.30e-3)" "unprognostic (2.64e-1)" "unprognostic (3.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (4.37e-2)" "unprognostic (5.74e-3)" "unprognostic (4.08e-2)" "unprognostic (1.72e-1)" "unprognostic (7.16e-2)" "unprognostic (1.34e-1)" "unprognostic (4.05e-1)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.48e-1)" "unprognostic (1.47e-1)" "unprognostic (3.09e-1)" "unprognostic (1.69e-1)" 7.9 9.7 4.1 7.9 4.1 7.6 8.0 5.2 6.6 12.7 12.0 6.7 9.6 8.2 15.2 9.4 13.5 9.9 11.6 6.2 4.3 4.9 7.3 10.6 7.5 7.7 4.8 3.6 13.5 12.5 5.4 10.0 7.4 4.7 15.8 11.9 6.8 6.9 9.8 7.6 8.1 9.7 15.8 4.7 12.3 10.5 7.9 4.4 11.2 21.9 9.3 9.8 17.5 8.9 7.7 7.8 5.9 10.2 7.1 8.5 4.5 6.3 11.1 5.5 10.2 5.1 15.1 4.2 5.0 9.4 10.3 13.9 15.3 6.5 15.9 4.3 4.4 6.8 6.7 9.6 11.6 6.5 9.2 5.7 7.6 6.5 5.8 11.9 6.0 13.7 11.6 9.0 12.5 3.7 9.9 5.1 6.1 8.8 1.4 8.0 5.2 11.1 2.3 10.4 9.0 6.4 8.1 6.9 9.7 4.0 6.1 8.1 10.3 6.9 4.2 8.3 5.5 6.8 13.3 4.5 5.0 10.3 3.6 11.5 5.2 5.9 9.6 0.1 4.2 9.8 5.0 7.7 5.8 4.5 7.8 6.7 8.5 7.1 0.9 7.1 10.2 5.9 5.3 4.5 4.1 4.1 5.2 6.6 4.3 4.9 4.8 3.6 4.7 4.4 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300993-43323108 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "EFO-21: 27.9;HUVEC TERT2: 61.6;TIME: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "basophil: 3.4;NK-cell: 5.4" "Group enriched" "Detected in many" 22 "granulocytes: 3.4;NK-cells: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" 75000000 "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 39.4 5.4 3.9 6.6 6.0 1.0 43.6 2.5 6.0 10.8 8.4 4.5 4.2 4.5 18.6 10.9 7.8 10.2 11.1 15.1 4.9 4.2 9.4 10.8 22.0 13.1 6.4 3.1 7.0 3.0 2.7 5.1 39.9 5.5 8.6 3.0 6.9 6.0 6.9 17.8 4.2 5.8 12.1 5.3 14.8 5.1 5.1 3.8 1.1 13.9 10.2 3.1 9.0 14.7 0.0 0.2 3.4 0.0 5.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 5.1 0.3 0.0 2.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.5 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.4 0.0 0.1 0.0 0.0 3.9 6.0 2.5 6.0 4.9 4.2 6.4 3.1 5.5 3.8 TIPARP "DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 24.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules Microtubules "HPA036796: AB_10672268" "prognostic favourable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 31.6 29.8 10.9 11.1 24.7 31.8 19.9 7.1 16.3 16.2 12.7 14.2 18.8 6.8 18.3 20.7 27.2 27.8 18.8 26.5 16.0 9.4 14.2 21.3 20.2 15.2 16.2 6.2 37.0 14.5 73.8 11.4 6.1 30.9 13.6 7.5 10.0 8.2 36.0 17.4 26.2 22.1 21.6 37.4 8.4 11.3 23.1 12.5 8.4 10.8 19.1 13.8 18.7 16.7 3.7 3.3 24.1 5.4 7.0 6.0 2.2 12.5 8.8 3.0 2.5 11.1 8.1 2.4 20.9 17.0 10.7 14.9 5.0 26.1 3.7 6.8 23.7 13.0 7.5 50.2 15.9 7.9 5.6 6.3 9.2 3.4 4.7 2.1 11.6 6.6 31.5 10.8 26.2 9.7 4.9 15.1 37.0 2.4 1.8 2.8 3.4 7.4 3.0 6.8 12.8 11.2 5.9 9.2 2.3 16.4 5.1 3.5 7.9 3.7 20.9 4.6 1.5 8.6 7.5 16.9 3.0 3.3 7.9 3.3 15.5 24.1 3.5 4.7 4.2 2.2 6.0 1.9 4.2 5.6 2.3 3.7 2.6 3.5 10.7 7.0 5.4 3.3 4.7 2.2 10.9 24.7 7.1 16.3 16.0 9.4 16.2 6.2 30.9 12.5 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174075-78187233 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.8;lymphoid tissue: 41.8;tongue: 33.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 21.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB004683 Enhanced "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavourable (6.87e-4)" "prognostic unfavourable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavourable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 5.3 2.0 2.1 21.4 4.5 32.8 4.8 1.1 1.9 3.7 11.4 2.2 1.9 8.5 2.4 4.8 18.9 2.2 7.0 4.3 1.6 0.7 7.9 6.2 9.3 15.7 3.1 1.6 2.1 3.6 0.1 1.3 8.6 2.1 2.3 7.9 0.5 4.6 2.0 2.0 6.2 8.5 4.4 1.7 9.0 9.4 3.6 1.6 41.8 1.3 33.0 20.5 3.1 5.8 4.0 2.1 1.1 1.2 6.2 21.2 3.5 65.1 54.2 10.8 13.6 1.0 4.3 7.1 32.4 17.0 48.2 66.9 47.8 27.5 21.2 11.4 19.4 29.7 9.8 28.9 25.0 7.3 36.2 37.4 19.4 31.3 0.3 15.8 24.2 2.1 0.9 25.1 3.4 19.6 23.0 47.0 18.5 48.7 7.9 8.9 5.6 37.8 21.4 43.8 47.3 12.8 21.2 4.9 14.3 24.8 68.2 9.1 46.0 21.3 9.0 47.4 46.6 33.8 41.6 19.8 10.3 27.3 23.3 10.7 21.3 0.0 0.7 0.0 1.1 1.2 0.5 4.0 5.3 2.7 2.1 1.2 0.3 1.4 1.1 6.2 1.0 0.7 21.2 3.5 2.1 4.5 1.1 1.9 1.6 0.7 3.1 1.6 2.1 1.6 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2, mitochondrial" O00142 16 66508003-66552544 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favourable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 34.0 25.4 18.5 9.0 18.9 6.2 25.5 13.1 22.4 19.8 10.9 17.2 18.5 9.5 15.2 29.0 11.0 17.4 18.3 15.2 19.2 15.5 20.9 27.8 16.5 11.5 18.2 18.5 23.7 21.6 50.2 18.0 12.9 27.9 14.9 11.5 13.7 18.1 18.8 20.8 10.0 10.5 17.0 28.2 17.4 12.0 29.4 15.5 6.5 23.4 9.0 8.7 15.5 18.6 1.4 12.6 10.3 15.6 4.4 4.3 3.3 4.7 9.4 5.1 5.3 28.1 23.1 0.3 8.2 10.0 6.6 7.7 2.8 10.5 0.1 9.1 25.6 4.1 2.5 6.8 4.3 3.1 2.3 0.8 6.0 5.2 20.0 1.3 3.6 17.2 6.5 7.6 10.5 9.8 2.8 11.1 15.5 1.6 2.5 6.2 2.5 5.6 2.8 9.2 10.9 20.3 4.0 1.9 3.3 24.8 2.5 10.7 3.8 6.8 10.4 12.8 6.6 10.3 3.0 12.5 5.2 5.6 15.4 2.5 7.5 4.7 15.6 10.3 4.3 13.3 3.3 0.9 2.9 3.0 12.6 1.4 1.4 2.3 8.2 4.4 9.8 5.2 2.8 3.3 18.5 18.9 13.1 22.4 19.2 15.5 18.2 18.5 27.9 15.5 TKFC "DAK, DKFZP586B1621, NET45" ENSG00000149476 "Triokinase and FMN cyclase" Q3LXA3 11 61333210-61353295 "Enzymes, Predicted intracellular proteins" "Kinase, Lyase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.2;liver: 42.8" "Cell line enhanced" "Detected in all" "Hep G2: 39.8;RPMI-8226: 42.0;T-47d: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039486, HPA048186" Enhanced Approved Nucleoplasm,Cytosol 4800000 "Nucleoplasm, Cytosol" "HPA039486: AB_10795402, HPA048186: AB_2680305" "unprognostic (4.00e-1)" "unprognostic (3.13e-1)" "unprognostic (7.42e-2)" "prognostic favourable (1.32e-5)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (3.02e-2)" "unprognostic (2.81e-3)" "unprognostic (1.49e-1)" "unprognostic (2.47e-1)" "unprognostic (1.51e-1)" "unprognostic (2.15e-1)" "prognostic favourable (8.38e-5)" "unprognostic (2.07e-2)" "unprognostic (8.96e-2)" "unprognostic (3.30e-1)" "unprognostic (4.02e-1)" 3.1 34.7 3.6 6.1 5.3 5.3 4.6 3.7 7.3 3.4 43.4 7.6 8.0 69.5 4.6 7.8 6.2 5.9 8.8 2.8 3.1 2.6 17.4 42.8 3.5 5.2 3.3 5.3 4.5 9.8 3.0 5.5 3.9 4.4 5.0 2.3 7.3 7.2 7.1 4.6 6.1 90.2 2.6 3.1 5.4 5.7 17.1 3.4 5.5 6.4 6.3 6.7 5.4 3.9 9.7 18.4 5.4 11.4 5.3 10.9 7.8 6.0 15.3 2.7 9.3 3.4 3.7 7.6 3.5 3.8 3.3 2.1 6.9 14.6 7.5 12.4 2.5 8.5 5.0 6.6 1.1 12.9 6.7 4.6 8.1 39.8 5.8 3.9 7.8 5.8 4.5 3.1 11.0 3.3 8.1 14.5 2.4 27.4 3.4 3.6 7.4 10.5 6.1 4.2 42.0 5.3 10.7 10.4 9.3 6.5 11.4 5.9 42.0 2.8 3.9 6.6 6.9 5.2 2.1 26.9 22.2 6.7 6.8 3.6 6.0 2.3 11.4 5.4 6.7 6.8 8.6 9.7 7.8 6.5 18.4 9.7 5.6 5.9 0.9 5.3 5.3 9.0 10.9 7.8 3.6 5.3 3.7 7.3 3.1 2.6 3.3 5.3 4.4 3.4 TKT ENSG00000163931 Transketolase P29401 3 53224707-53256052 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 216.3" "Cell line enhanced" "Detected in all" "A549: 161.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 63.0;eosinophil: 41.5;intermediate monocyte: 31.0;myeloid DC: 32.5;neutrophil: 60.1;non-classical monocyte: 35.5" "Group enriched" "Detected in all" 8 "dendritic cells: 32.5;granulocytes: 60.1;monocytes: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm 190000000 Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavourable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 53.6 37.0 21.2 24.1 26.0 216.3 70.1 18.1 24.3 19.0 24.3 21.1 9.9 31.8 16.9 9.5 60.4 21.8 36.5 15.3 19.4 23.0 51.9 27.4 50.1 45.6 33.4 16.0 35.2 69.9 22.5 16.9 29.8 28.7 25.2 19.6 17.5 21.0 21.6 5.2 16.8 22.5 34.5 28.2 45.6 24.5 10.8 23.3 44.8 67.7 37.9 25.1 58.2 57.3 6.8 32.5 60.1 63.0 4.7 5.7 37.6 31.8 161.2 23.1 25.6 51.5 63.0 47.1 21.6 37.5 37.4 35.8 44.5 82.0 40.1 10.4 31.5 46.2 40.0 81.3 11.1 13.3 22.2 26.7 112.8 66.8 63.0 32.6 18.1 45.5 46.8 44.8 23.1 47.1 19.0 17.5 15.2 38.9 34.0 36.5 78.3 38.9 20.6 10.5 74.5 58.5 54.2 15.0 11.1 40.2 64.4 38.8 20.0 45.2 35.2 11.6 17.9 34.1 41.2 10.1 18.9 24.0 25.3 33.0 21.5 7.0 63.0 41.5 3.0 31.0 3.8 6.8 4.4 3.4 32.5 3.5 4.6 3.4 60.1 4.7 35.5 5.5 5.7 37.6 21.2 26.0 18.1 24.3 19.4 23.0 33.4 16.0 28.7 23.3 TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295671-154330350 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "blood: 28.6;testis: 103.6" "Cell line enriched" "Detected in single" 157 "THP-1: 100.4" "Cancer enriched" "Detected in many" 8 "testis cancer: 44.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 28.6;gdT-cell: 12.0" "Group enriched" "Detected in many" 6 "granulocytes: 28.6;T-cells: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000505, CAB032191" Enhanced Supported Cytosol Cytosol "CAB032191: , HPA000505: AB_1858022" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.98e-1)" "unprognostic (5.80e-3)" "unprognostic (2.43e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.34e-2)" "unprognostic (3.90e-2)" "unprognostic (5.04e-2)" "unprognostic (2.38e-1)" 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 103.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.6 0.1 3.3 12.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 100.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.0 28.6 12.0 0.1 1.8 0.0 1.4 1.1 0.0 0.0 3.1 2.7 0.4 3.3 0.1 0.1 1.5 2.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 TKTL2 "DKFZP434L1717, FLJ32975" ENSG00000151005 "Transketolase like 2" Q9H0I9 4 163471093-163473746 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 66.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (2.19e-1)" "unprognostic (1.55e-1)" "unprognostic (8.62e-2)" "unprognostic (2.05e-2)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (7.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.15e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 66.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 13.8 20.1 22.0 32.9 21.0 14.4 26.2 18.3 23.2 19.6 20.2 8.4 22.3 13.7 16.1 16.1 14.1 14.4 16.2 12.7 20.6 19.3 19.5 21.4 22.1 33.7 21.7 20.8 21.5 19.8 37.8 21.0 36.0 18.3 18.0 18.2 10.8 16.4 30.3 18.6 15.4 18.9 20.5 18.7 26.0 19.9 24.2 12.2 28.0 25.7 11.1 21.7 21.9 19.1 10.5 5.3 11.3 5.5 9.5 12.3 6.6 8.5 8.3 12.1 9.4 8.6 8.7 13.4 11.8 17.3 12.0 10.1 11.5 13.9 17.7 9.7 17.8 7.3 15.3 13.2 13.2 21.0 7.7 20.5 10.4 14.9 9.3 25.9 10.4 9.4 13.5 23.8 15.7 13.1 21.0 15.1 7.2 10.6 21.7 8.3 11.1 4.7 16.4 14.7 18.2 9.9 16.5 13.8 10.7 12.9 9.2 8.8 7.5 9.1 17.8 10.7 13.1 7.0 9.2 12.7 21.3 32.1 13.3 10.7 10.8 11.3 3.9 6.5 6.6 3.0 9.1 10.5 10.7 7.2 3.5 10.5 12.3 8.1 5.0 9.5 5.5 5.3 10.0 6.6 22.0 21.0 18.3 23.2 20.6 19.3 21.7 20.8 18.3 12.2 TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-2)" "unprognostic (9.53e-3)" "unprognostic (6.57e-2)" "prognostic unfavourable (9.40e-4)" "unprognostic (4.53e-2)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (4.78e-2)" "unprognostic (5.32e-2)" "unprognostic (9.79e-2)" "unprognostic (4.32e-2)" "unprognostic (4.88e-1)" "unprognostic (7.30e-2)" 7.4 6.4 8.3 7.3 7.2 12.0 12.5 7.8 14.0 5.8 7.8 4.0 3.1 7.4 9.0 3.1 9.0 6.2 9.9 17.8 7.7 7.4 5.7 5.0 6.9 8.7 7.7 7.3 8.5 8.9 5.6 6.9 9.0 10.4 6.6 5.3 7.5 8.6 8.7 11.7 8.7 10.1 6.5 8.6 8.9 6.7 47.9 5.7 4.1 11.7 3.1 10.0 8.5 7.2 4.6 3.6 8.6 2.8 6.6 4.9 1.5 15.5 14.3 24.8 26.2 8.1 10.5 14.4 17.2 13.4 20.4 18.7 14.9 14.0 30.5 8.8 11.2 10.6 17.5 7.3 19.5 16.1 13.9 20.7 13.5 15.0 14.5 21.8 13.2 9.0 10.0 13.7 16.6 10.1 20.5 13.9 10.9 33.9 31.1 7.8 15.7 12.0 21.3 32.6 9.7 9.6 15.7 26.7 36.2 14.7 10.0 22.1 17.0 19.6 13.6 28.6 27.2 12.9 19.4 16.1 20.1 28.0 11.8 11.2 14.9 3.7 2.8 8.6 2.5 2.2 2.6 4.5 4.4 3.1 2.5 4.6 3.5 4.6 5.5 6.6 2.4 3.6 4.9 1.5 8.3 7.2 7.8 14.0 7.7 7.4 7.7 7.3 10.4 5.7 TMEM129 D4S2561E ENSG00000168936 "Transmembrane protein 129" A0AVI4 4 1715952-1721358 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (6.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.12e-1)" "unprognostic (2.85e-1)" "unprognostic (4.04e-2)" "unprognostic (1.22e-3)" "unprognostic (7.35e-3)" "unprognostic (4.82e-2)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (2.51e-3)" "unprognostic (2.81e-1)" "prognostic favourable (9.64e-8)" "unprognostic (1.47e-1)" "unprognostic (6.49e-2)" "unprognostic (3.08e-1)" "unprognostic (2.36e-3)" 18.2 19.8 17.6 11.3 21.7 6.0 11.0 19.3 25.6 16.4 17.9 22.1 21.5 23.7 16.1 14.6 18.7 18.0 16.5 29.0 18.3 16.2 22.4 26.3 14.5 12.8 20.1 14.0 17.3 32.6 25.9 24.9 15.8 16.9 17.5 9.6 20.4 34.0 22.8 20.9 15.7 17.6 12.7 14.9 14.6 16.0 15.0 20.0 11.5 32.4 11.0 12.3 14.6 10.5 2.1 7.7 0.7 3.3 2.0 3.6 2.1 9.0 10.5 8.9 13.1 16.3 9.6 10.3 7.3 12.0 7.7 8.3 7.8 22.6 11.9 8.9 7.9 9.1 4.5 9.4 1.3 8.2 13.4 6.5 7.5 9.8 13.4 9.2 11.8 15.9 20.2 4.2 3.9 11.9 7.3 8.8 7.2 7.1 12.6 15.0 13.8 13.1 8.1 4.6 14.7 19.2 10.1 20.6 12.7 6.3 11.2 9.6 23.1 4.3 8.1 9.0 6.9 7.8 7.1 22.4 6.7 5.7 10.4 12.7 9.5 0.3 3.3 0.1 3.6 2.2 3.1 1.6 3.2 2.6 3.4 2.1 2.2 1.5 0.7 2.0 2.4 7.7 1.5 2.1 17.6 21.7 19.3 25.6 18.3 16.2 20.1 14.0 16.9 20.0 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171061339-171460408 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell line enhanced" "Detected in many" "AF22: 19.6;HEL: 26.6;HMC-1: 30.3;HUVEC TERT2: 19.5;WM-115: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 23 "basophil: 4.4;eosinophil: 10.5;gdT-cell: 4.2;MAIT T-cell: 5.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.7;naive CD4 T-cell: 6.7;naive CD8 T-cell: 3.8;NK-cell: 2.7;T-reg: 5.3" "Group enriched" "Detected in many" 29 "granulocytes: 10.5;NK-cells: 2.7;T-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol 9100 Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 2.2 5.4 29.0 7.4 30.9 4.9 3.6 21.1 26.1 1.9 10.9 12.2 4.1 25.8 4.3 2.1 5.6 4.3 7.1 11.2 30.9 14.8 5.6 4.6 11.3 7.9 11.4 18.3 2.6 5.2 0.7 9.0 3.1 13.6 5.6 9.5 3.5 2.9 7.3 23.2 1.6 25.6 6.0 14.5 5.8 9.2 10.7 21.1 3.7 7.1 2.2 6.9 6.4 2.6 0.2 0.0 10.5 0.1 2.7 6.7 1.1 0.3 0.5 19.6 2.0 0.3 0.0 4.6 4.1 1.1 3.2 2.2 17.5 7.3 0.0 1.4 3.7 6.0 2.8 1.1 3.5 0.1 4.3 26.6 1.5 0.0 9.4 5.2 30.3 2.8 2.9 1.9 0.4 19.5 9.6 0.0 0.5 0.4 1.6 6.7 8.0 7.6 0.0 5.0 7.0 6.3 0.0 0.9 1.0 2.5 0.2 4.3 8.8 1.3 0.2 0.0 3.4 8.9 3.0 0.0 0.0 0.0 0.9 5.9 22.7 4.4 0.1 10.5 4.2 0.0 5.2 0.0 5.0 3.7 0.0 0.2 6.7 3.8 0.1 2.7 0.1 0.0 5.3 1.1 29.0 30.9 21.1 22.2 30.9 14.8 11.4 18.3 13.6 21.1 TNK1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 6.4;HaCaT: 10.4;HBEC3-KT: 6.9;hTCEpi: 7.8;T-47d: 8.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 6.4;cerebellum: 11.4;cerebral cortex: 4.0;pons and medulla: 4.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 1.6;T-cells: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favourable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favourable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favourable (1.52e-4)" 3.4 0.6 1.1 2.2 6.4 0.4 7.9 11.4 4.0 5.4 11.7 0.4 7.7 7.1 5.1 5.3 7.2 3.5 6.3 2.0 1.0 0.4 4.6 6.9 3.2 2.7 1.5 0.8 4.4 6.8 5.4 2.7 2.5 4.3 8.9 4.5 7.7 10.5 4.8 1.8 8.3 11.3 5.1 0.7 2.4 9.6 2.2 0.6 0.6 11.6 5.7 5.2 4.5 4.4 1.6 0.1 0.4 0.0 0.0 3.8 0.6 6.4 1.0 0.2 0.4 0.0 0.0 4.3 0.2 0.0 0.4 0.4 3.3 3.0 0.0 2.6 0.3 10.4 0.0 6.9 0.1 0.7 1.5 0.0 3.7 1.8 0.4 0.0 0.2 0.1 7.8 0.0 1.2 0.0 0.8 0.0 0.0 4.9 0.6 0.0 0.9 0.9 0.2 0.2 0.7 4.8 3.0 0.2 0.5 3.5 5.2 1.0 8.6 0.1 1.7 0.2 0.8 0.2 0.0 0.5 1.0 0.1 0.1 0.4 0.5 0.0 0.0 0.0 1.0 0.0 1.9 1.6 1.8 1.2 0.1 1.5 3.3 3.8 0.4 0.0 0.0 0.0 0.8 0.6 1.1 6.4 11.4 4.0 1.0 0.4 1.5 0.8 4.3 0.6 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041954 Approved Approved Cytosol Cytosol "HPA041954: AB_10794164" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavourable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favourable (1.00e-4)" 9.2 7.6 36.3 16.2 27.6 38.9 8.5 20.7 43.7 6.0 6.3 17.6 3.8 6.6 8.0 6.6 13.0 10.7 6.5 10.6 28.4 21.8 4.1 7.2 9.3 18.1 21.6 31.8 8.6 7.8 5.1 19.3 8.4 20.0 10.8 3.9 5.3 16.8 8.2 30.5 37.1 6.9 7.6 10.3 17.0 12.1 7.7 21.8 3.4 4.6 9.8 12.8 7.7 12.3 6.1 3.1 6.3 3.2 0.9 1.9 1.2 31.3 3.0 5.1 5.4 7.1 4.5 30.5 6.0 5.8 3.6 3.3 4.8 24.3 9.1 21.2 8.2 11.2 4.4 7.5 1.1 21.4 5.6 8.2 10.2 3.5 3.2 4.2 4.1 3.3 11.9 5.0 6.0 4.6 3.3 12.7 3.4 23.1 1.8 15.4 4.8 11.3 5.3 6.1 9.2 3.2 15.2 6.2 6.3 3.9 15.9 7.8 26.0 5.3 7.5 8.4 4.9 4.4 16.8 27.6 3.0 5.6 7.5 13.8 6.2 2.0 2.4 0.9 1.9 3.2 1.1 2.7 1.8 1.0 1.1 6.1 1.4 1.3 6.3 0.9 2.8 3.1 0.2 1.2 36.3 27.6 20.7 33.3 28.4 21.8 21.6 31.8 20.0 21.8 TNKS "PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555914-9782346 "Enzymes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 9.1 13.4 17.8 8.7 19.6 14.6 14.0 26.5 22.3 18.1 8.9 17.0 12.5 8.5 14.9 25.3 7.7 11.9 8.9 9.5 18.6 17.9 9.0 9.1 10.3 12.9 28.7 17.2 19.2 10.2 23.9 20.0 11.0 20.1 11.5 10.0 10.9 9.4 11.7 22.1 15.6 9.8 11.0 21.0 8.7 10.1 26.3 21.8 15.6 13.7 4.4 11.7 10.8 13.6 6.8 3.6 7.4 2.8 2.9 4.8 1.2 6.0 8.0 20.5 12.3 12.9 17.4 7.6 9.3 10.6 7.6 8.6 4.7 4.8 12.9 3.9 9.1 6.4 11.6 8.7 11.0 3.3 6.0 9.1 7.3 10.7 11.7 4.7 5.6 12.3 10.6 7.9 15.6 10.2 8.5 13.9 14.0 3.9 11.7 7.1 13.3 4.7 9.5 12.6 3.7 9.1 12.3 20.8 15.3 7.3 7.0 13.2 4.7 7.0 13.7 12.5 7.7 8.5 6.9 4.8 7.8 9.2 13.5 6.6 12.0 4.8 2.3 1.8 4.4 2.2 2.4 4.2 3.5 4.2 2.8 6.8 4.2 4.8 7.4 2.9 2.8 3.6 1.7 1.2 17.8 19.6 26.5 22.3 18.6 17.9 28.7 17.2 20.1 21.8 TNKS2 "PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798312-91865276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules Microtubules "HPA036606: AB_10673470" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (4.16e-1)" "unprognostic (1.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" 17.6 16.3 16.7 23.0 18.6 26.9 18.4 27.9 20.0 18.8 13.9 18.3 18.3 11.9 18.9 18.8 24.7 16.7 17.2 12.2 16.6 14.9 14.6 16.8 17.0 22.9 20.3 14.9 26.0 19.3 20.8 26.7 47.5 16.1 16.7 14.3 16.1 21.4 16.0 39.7 23.9 16.5 18.9 18.0 22.8 15.8 9.5 17.9 42.9 24.5 21.0 23.8 18.6 18.9 3.6 5.2 3.8 2.5 3.3 3.5 1.4 14.3 12.3 25.3 21.4 17.9 16.4 28.3 15.5 28.4 19.0 23.4 10.9 11.8 13.6 7.5 20.2 15.6 15.8 12.0 26.9 13.7 15.3 11.2 11.8 12.1 17.5 21.6 16.8 16.6 15.9 19.2 34.3 17.8 8.3 15.1 19.7 7.7 18.6 14.8 12.7 8.3 17.5 15.8 10.3 13.0 15.6 6.6 11.9 15.6 6.9 19.3 16.7 15.1 19.1 10.3 8.7 13.5 14.7 19.1 15.6 17.7 13.5 16.3 9.1 1.0 2.5 3.8 3.5 2.3 3.0 3.5 3.3 3.2 3.4 3.6 2.8 2.4 2.5 3.3 2.2 5.2 1.7 1.4 16.7 18.6 27.9 20.0 16.6 14.9 20.3 14.9 16.1 17.9 TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235401-74544428 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "heart muscle: 44.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.9;HSkMC: 2.7;RPTEC TERT1: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.3;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 5 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 1.0" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (3.83e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-1)" "unprognostic (3.40e-2)" "unprognostic (3.05e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-1)" "unprognostic (9.66e-2)" "unprognostic (5.04e-2)" "unprognostic (1.80e-1)" "unprognostic (3.59e-3)" "unprognostic (4.88e-3)" "unprognostic (1.20e-1)" "unprognostic (8.80e-2)" "unprognostic (8.77e-2)" 0.7 0.6 1.1 0.5 1.5 0.0 1.0 6.0 1.7 0.5 0.5 0.5 0.5 0.2 0.5 1.7 0.5 0.7 0.5 44.6 1.1 1.3 2.2 0.5 0.5 0.5 0.6 0.5 0.7 0.5 0.3 0.6 0.5 0.9 0.5 0.3 0.5 0.5 1.2 0.5 0.9 0.5 0.6 0.5 0.5 0.1 1.8 0.5 0.5 0.6 0.5 0.5 0.5 0.5 0.3 1.9 0.0 2.3 0.0 1.0 0.1 0.0 0.6 0.7 0.0 0.5 1.6 0.0 0.0 1.3 0.3 1.0 0.0 3.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.5 2.7 1.6 0.2 0.0 0.5 0.0 0.8 1.1 0.0 0.2 0.2 1.1 0.0 0.2 0.0 0.0 2.6 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.0 0.1 2.3 0.0 0.1 0.3 1.0 0.1 0.3 0.2 0.4 0.0 0.0 0.2 1.9 0.0 0.1 1.1 1.5 6.0 1.7 1.1 1.3 0.6 0.5 0.9 0.5 TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein" Q9NS56 9 32540544-32552553 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm Nucleoplasm "HPA060640: , HPA065661: " "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-2)" "unprognostic (9.94e-2)" "prognostic favourable (7.07e-4)" "unprognostic (2.70e-1)" "unprognostic (3.61e-1)" "prognostic favourable (6.64e-6)" "unprognostic (1.22e-1)" "unprognostic (5.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" 16.0 12.5 12.7 8.5 16.0 22.9 13.7 18.6 15.1 14.0 12.2 9.6 9.5 8.8 12.9 11.4 13.1 10.5 11.7 9.3 15.9 9.6 14.6 17.4 10.6 10.0 20.1 5.2 17.5 13.2 19.6 19.5 17.9 14.8 13.1 10.3 9.2 11.0 10.8 10.9 10.2 16.8 12.3 17.8 12.4 10.7 18.9 15.0 15.5 15.6 9.8 10.5 16.3 16.0 5.2 4.9 33.4 5.9 7.1 7.4 3.4 8.0 7.5 10.3 9.0 12.6 11.4 6.5 10.3 9.7 8.6 10.0 4.6 4.1 13.1 5.9 10.2 5.4 12.1 11.7 12.1 10.9 6.6 44.2 13.0 5.8 7.8 12.5 12.2 9.2 13.1 12.4 8.8 10.4 7.6 6.8 13.9 4.3 11.2 23.1 13.7 7.6 11.6 9.2 5.9 11.4 8.5 5.1 8.2 10.3 5.6 6.7 5.7 7.2 10.9 9.4 9.6 4.9 7.6 4.8 7.7 14.2 8.7 7.2 4.2 14.6 4.9 10.0 5.0 4.6 5.4 4.6 5.4 5.8 4.9 5.2 7.4 7.2 33.4 7.1 5.9 4.0 6.3 3.4 12.7 16.0 18.6 15.1 15.9 9.6 20.1 5.2 14.8 15.0 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689779 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavourable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavourable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 11.2 14.5 12.7 12.6 15.3 9.6 16.8 8.1 20.3 14.1 11.7 13.7 5.3 8.8 14.8 8.9 16.9 12.2 12.6 9.9 12.1 11.3 12.7 13.6 10.6 18.2 13.1 12.8 15.3 10.1 11.8 15.7 14.9 12.1 15.5 11.4 12.6 13.8 12.2 12.4 16.8 11.2 12.7 10.6 13.2 13.3 26.4 11.8 21.9 16.6 13.1 21.1 14.3 12.7 14.7 19.1 21.7 12.4 16.2 18.5 12.2 3.9 2.7 5.8 5.1 6.1 5.1 5.2 5.5 5.2 7.4 5.4 7.7 2.5 9.5 8.4 4.6 6.2 7.4 6.4 6.4 2.3 3.7 9.6 2.7 6.9 8.1 6.2 69.0 6.7 7.8 5.1 5.0 4.8 6.4 4.2 6.2 5.8 9.3 10.3 4.7 9.2 5.4 5.2 5.6 4.9 4.3 6.9 3.6 6.7 13.6 27.0 4.9 6.8 4.9 8.6 5.0 5.6 6.1 4.6 5.7 7.6 5.0 4.7 4.0 21.7 12.4 20.6 13.7 11.5 15.8 14.7 14.8 15.6 12.6 14.2 16.4 14.0 2.0 16.2 10.2 19.1 18.5 12.2 12.7 15.3 8.1 20.3 12.1 11.3 13.1 12.8 12.1 11.8 TPK1 "HTPK1, PP20" ENSG00000196511 "Thiamin pyrophosphokinase 1" Q9H3S4 7 144451941-144836395 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AN3-CA: 26.6;CACO-2: 6.3;EFO-21: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021545, HPA021849" Approved Approved Vesicles 78000 Vesicles "HPA021545: AB_1858209, HPA021849: AB_1858210" "unprognostic (4.05e-2)" "unprognostic (3.28e-2)" "unprognostic (2.38e-2)" "unprognostic (3.32e-2)" "unprognostic (2.42e-1)" "unprognostic (1.63e-1)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (6.06e-2)" "unprognostic (1.45e-3)" "unprognostic (3.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (9.22e-3)" 12.2 7.4 5.1 9.6 4.7 3.6 7.6 4.0 7.2 4.3 8.4 4.2 2.4 18.2 5.1 5.0 3.3 3.9 5.4 6.4 5.6 6.6 6.0 6.2 8.8 23.3 4.9 3.1 4.4 3.3 3.6 4.6 7.0 4.4 3.7 8.5 8.9 7.1 4.1 3.0 2.9 13.9 5.1 6.0 15.1 4.0 5.9 2.0 5.1 4.9 4.1 14.2 5.5 3.3 5.4 9.6 3.4 7.4 4.0 5.5 3.8 0.2 0.2 0.2 26.6 0.2 0.2 2.2 0.1 0.1 0.0 0.0 6.3 1.0 0.4 8.1 0.4 0.0 0.5 0.3 0.2 1.6 0.4 0.1 0.1 0.1 0.7 2.0 0.6 0.5 0.5 0.3 0.4 5.1 0.5 1.2 0.1 0.8 0.5 3.0 0.6 2.2 0.2 0.6 0.9 4.1 2.3 0.2 0.0 0.4 0.0 0.4 0.3 3.8 6.1 0.3 0.6 0.5 0.3 0.6 1.4 0.6 0.9 5.1 0.2 0.3 7.3 0.2 3.9 5.3 4.0 5.0 4.4 3.5 9.6 5.4 5.2 4.2 3.4 4.0 7.4 2.3 5.5 3.8 5.1 4.7 4.0 7.2 5.6 6.6 4.9 3.1 4.4 2.0 TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155074 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 48.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019851 Enhanced "HPA019851: AB_1858213" "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavourable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favourable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favourable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" 5.3 13.2 11.5 6.6 10.2 4.9 5.6 13.1 14.3 4.6 18.2 4.1 6.2 18.4 6.5 10.1 8.9 4.1 7.6 6.5 9.0 8.0 40.2 36.2 6.5 6.2 9.3 7.5 3.8 9.4 12.9 11.6 3.3 8.5 6.2 19.4 6.9 12.9 7.2 7.0 5.7 29.4 6.2 7.2 9.4 6.6 4.1 7.5 5.4 48.2 6.3 5.3 6.4 5.6 1.6 16.9 3.7 23.8 5.4 8.3 8.3 11.7 3.6 4.0 9.8 6.6 12.9 9.8 13.7 15.2 11.7 18.3 8.3 2.9 1.5 10.2 18.0 5.9 5.6 9.8 19.6 7.7 8.1 9.7 6.1 12.1 7.2 4.4 8.8 7.4 10.6 13.0 8.3 16.2 19.1 2.8 8.5 5.4 4.5 6.1 6.6 10.3 5.7 9.8 6.6 13.6 12.1 6.5 5.0 8.9 15.9 17.5 11.5 4.5 6.9 26.9 5.2 14.0 19.3 4.1 18.2 3.8 9.6 6.1 26.9 3.4 12.0 3.7 6.5 23.8 8.3 1.5 5.3 6.2 16.9 1.6 4.8 6.5 1.2 5.4 19.6 3.7 8.2 8.3 11.5 10.2 13.1 14.3 9.0 8.0 9.3 7.5 8.5 7.5 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205199-66420543 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 21.3;neutrophil: 17.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: " "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavourable (8.16e-6)" "prognostic unfavourable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavourable (3.73e-5)" 15.4 12.8 16.7 9.8 28.2 5.6 11.2 12.2 19.2 34.0 7.7 8.8 3.4 3.4 20.2 13.8 10.8 10.9 34.2 6.6 26.1 22.2 13.4 38.9 9.0 5.9 15.3 12.2 11.5 7.1 8.1 19.6 23.2 28.1 15.5 7.9 9.7 5.4 15.8 2.9 6.2 5.9 35.7 27.5 9.0 10.0 19.6 11.4 0.3 10.7 3.2 5.2 27.2 19.9 6.3 0.1 21.3 1.1 3.9 2.0 0.8 4.2 2.6 6.7 8.6 20.6 16.5 2.1 8.2 18.9 10.1 14.3 8.2 2.5 0.5 6.6 16.7 3.3 6.3 9.3 13.4 1.2 3.6 0.9 6.4 6.3 24.4 0.6 0.7 23.3 7.3 19.3 8.5 12.2 0.4 3.8 15.4 2.3 0.0 1.1 6.1 3.5 2.9 5.4 4.3 10.4 4.6 3.9 16.7 10.3 0.8 22.0 3.3 1.7 23.2 12.9 8.2 9.2 14.8 3.5 4.8 1.7 11.4 2.5 18.2 21.3 1.1 10.7 0.4 0.0 0.3 2.4 0.2 0.3 0.1 6.3 1.1 2.0 17.3 3.9 0.0 0.0 0.0 0.8 16.7 28.2 12.2 19.2 26.1 22.2 15.3 12.2 28.1 11.4 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521983-26596717 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 71.0;pancreas: 192.5" "Cell line enhanced" "Detected in all" "HMC-1: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" 33000 "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favourable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 5.8 8.4 4.7 3.7 3.6 5.2 9.0 2.1 6.9 4.6 2.9 3.0 7.4 3.5 4.7 31.8 4.5 4.1 3.2 5.2 5.2 3.2 5.7 20.0 10.7 4.8 3.7 3.6 2.4 192.5 1.1 2.9 11.0 3.2 3.8 2.3 4.0 2.8 7.9 8.6 4.0 3.1 3.2 2.8 8.9 3.0 4.8 3.1 3.0 12.2 2.2 5.2 4.5 6.7 4.3 20.0 71.0 15.1 57.2 46.4 35.2 4.2 3.1 4.1 2.0 8.8 6.7 5.7 9.6 17.3 7.8 7.2 2.1 2.2 7.2 2.5 17.2 6.7 3.0 6.6 4.5 2.9 5.8 17.4 1.9 4.4 3.6 2.0 56.0 7.2 10.6 7.9 2.7 14.4 17.4 22.7 5.9 4.8 8.0 13.6 5.3 3.1 7.5 5.5 20.1 2.3 4.8 3.1 2.1 4.4 3.9 5.3 1.8 8.4 11.4 9.7 21.9 7.9 9.2 7.4 10.2 6.9 7.3 7.8 8.7 71.0 13.4 18.6 46.4 14.5 13.0 4.1 10.9 34.5 8.4 4.3 5.4 31.4 28.4 57.2 15.1 20.0 12.2 35.2 4.7 3.6 2.1 6.9 5.2 3.2 3.7 3.6 3.2 3.1 TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol Cytosol "CAB004603: AB_628389, HPA009972: AB_1080350, HPA010634: AB_1080347" "unprognostic (7.77e-2)" "unprognostic (4.54e-3)" "prognostic unfavourable (9.32e-4)" "unprognostic (1.15e-1)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (4.91e-2)" "unprognostic (7.23e-2)" "unprognostic (4.28e-2)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.80e-3)" "unprognostic (5.52e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-2)" 7.3 6.6 8.7 20.3 10.4 15.9 8.6 16.0 10.0 7.3 8.7 7.4 7.3 11.1 12.3 6.9 12.3 9.0 8.3 8.3 7.5 6.5 8.5 12.3 11.5 19.7 11.2 8.3 6.8 13.9 5.9 8.8 12.1 8.1 10.2 6.2 7.5 13.0 10.1 6.4 13.0 10.4 10.6 8.2 13.8 10.7 13.7 6.4 16.4 14.7 5.2 15.9 8.4 37.5 12.6 11.5 6.7 8.3 10.1 17.4 6.2 10.6 32.9 8.9 7.9 2.5 4.0 17.4 8.8 4.9 12.9 8.8 20.3 19.3 13.3 11.5 5.5 28.1 12.2 14.4 5.3 20.2 9.9 10.0 29.7 12.6 3.7 9.8 10.4 3.0 4.4 10.5 6.0 6.0 16.8 15.2 5.7 15.5 15.9 14.1 14.5 14.8 15.1 13.7 18.1 7.9 8.4 14.6 6.8 11.0 25.8 10.0 18.5 11.6 6.8 16.9 10.9 11.0 14.7 6.3 10.3 13.2 6.0 8.1 12.4 1.3 3.7 6.7 10.4 4.2 14.6 12.6 11.1 13.0 4.9 10.0 9.1 10.9 3.3 10.1 8.3 11.5 17.4 6.2 8.7 10.4 16.0 10.0 7.5 6.5 11.2 8.3 8.1 6.4 TRAF3 "CAP-1, CD40bp, CRAF1, LAP1, RNF118" ENSG00000131323 "TNF receptor associated factor 3" Q13114 14 102777476-102911500 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Immunity, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002933 Uncertain "HPA002933: AB_1080352" "unprognostic (4.06e-2)" "unprognostic (1.75e-2)" "unprognostic (2.08e-2)" "unprognostic (4.49e-3)" "unprognostic (5.25e-2)" "unprognostic (4.17e-2)" "prognostic unfavourable (1.02e-5)" "unprognostic (1.31e-1)" "unprognostic (7.24e-2)" "unprognostic (1.16e-1)" "prognostic favourable (2.42e-5)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.71e-1)" "unprognostic (3.13e-2)" "unprognostic (2.12e-1)" 7.6 5.3 13.6 23.3 9.1 18.8 7.7 12.5 16.0 4.2 8.9 8.8 5.8 8.4 7.5 3.9 7.5 8.9 7.1 7.3 16.6 12.7 6.7 7.0 8.1 26.0 11.5 8.0 4.8 5.1 10.0 10.3 6.8 8.5 6.1 8.0 7.9 5.7 8.0 5.5 7.9 11.8 7.8 9.8 14.2 7.1 12.2 6.6 10.5 7.5 4.1 25.4 11.1 9.3 12.0 6.7 4.3 5.7 2.4 5.1 4.9 11.9 13.6 7.6 4.7 4.4 6.3 11.5 9.4 10.3 10.1 8.5 6.6 17.8 9.5 11.7 10.0 7.3 10.8 10.3 10.4 23.7 7.0 8.9 6.0 4.9 7.2 10.1 26.7 6.3 7.8 7.0 10.1 7.3 9.1 28.4 6.4 12.1 21.6 5.9 4.0 10.3 11.9 10.5 4.8 9.0 14.7 20.2 7.2 10.2 7.1 6.6 6.8 11.5 15.5 9.6 7.4 24.9 13.3 20.6 23.5 17.4 10.4 5.2 11.3 2.6 5.7 1.7 3.7 4.6 3.0 12.0 5.1 3.3 4.1 11.5 3.7 2.6 4.3 2.4 2.8 6.7 4.4 4.9 13.6 9.1 12.5 16.0 16.6 12.7 11.5 8.0 8.5 6.6 TRAF6 RNF85 ENSG00000175104 "TNF receptor associated factor 6" Q9Y4K3 11 36487027-36510272 "Enzymes, Predicted intracellular proteins" "DNA damage, Immunity, Osteogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004605, HPA019805, HPA020599" Approved Supported Nucleoli,Mitochondria Mitochondria Nucleoli "CAB004605: AB_628391, HPA019805: AB_1858231, HPA020599: AB_1858232" "unprognostic (2.48e-2)" "unprognostic (1.38e-1)" "unprognostic (2.83e-1)" "unprognostic (8.73e-2)" "unprognostic (1.71e-1)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.16e-2)" "unprognostic (9.22e-2)" "prognostic favourable (1.36e-4)" "unprognostic (2.82e-2)" "unprognostic (1.20e-1)" "unprognostic (3.92e-2)" "unprognostic (1.07e-1)" 13.0 11.0 12.9 8.5 17.0 31.8 11.9 18.1 15.0 10.6 10.7 13.6 8.2 9.5 12.9 9.8 12.4 11.5 9.4 13.9 9.8 7.1 11.2 12.3 15.2 9.2 14.8 10.6 14.6 11.3 11.0 11.9 10.3 12.7 9.6 10.5 10.5 11.0 9.3 13.9 12.7 12.5 12.1 10.1 13.0 10.3 15.0 12.8 18.5 15.6 6.7 10.8 11.3 13.0 10.6 7.7 27.7 11.4 9.6 13.1 8.5 5.1 6.5 12.6 7.1 11.9 8.7 5.5 7.8 8.4 7.2 9.5 5.7 3.5 6.8 4.8 8.2 9.7 10.0 7.9 12.0 11.1 11.7 6.5 5.1 5.1 7.7 7.2 8.0 8.1 11.1 3.9 11.8 10.1 9.7 7.4 9.0 6.3 11.5 3.9 6.8 6.0 7.6 17.1 3.8 8.7 10.7 2.1 11.1 7.8 7.6 5.5 8.7 7.0 8.0 10.3 9.1 9.4 9.4 8.7 7.3 7.3 5.8 5.2 7.7 27.7 8.0 20.9 11.9 11.4 11.7 10.6 10.3 11.6 7.7 8.1 10.0 13.1 11.1 9.6 8.2 4.5 8.0 8.5 12.9 17.0 18.1 15.0 9.8 7.1 14.8 10.6 12.7 12.8 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 16.0 18.2 18.3 22.3 20.6 28.5 39.1 28.7 25.6 22.1 29.4 9.1 21.1 37.3 20.4 18.3 32.9 21.9 36.9 21.0 18.3 14.8 21.3 47.3 18.3 40.9 13.4 14.7 19.3 41.6 17.7 20.3 19.5 12.8 16.2 16.9 13.0 24.4 23.1 25.5 32.2 37.8 28.8 14.1 21.4 25.1 13.2 10.6 26.1 20.3 30.9 21.9 21.9 28.9 6.7 12.3 7.7 13.9 3.0 7.1 5.2 20.8 26.7 15.3 27.3 15.8 30.0 18.0 16.1 20.3 19.0 17.1 32.4 27.0 13.4 19.1 20.5 24.5 14.3 28.6 7.2 21.1 18.3 19.1 35.6 24.8 21.0 20.3 27.7 29.6 23.9 18.3 24.0 36.7 20.3 18.1 18.0 47.7 20.8 23.6 30.0 13.1 38.9 25.4 26.8 15.3 11.2 30.8 25.6 13.5 25.9 17.6 29.4 25.0 27.6 23.1 32.5 21.5 17.5 26.2 19.4 17.7 13.2 13.2 17.9 3.7 10.0 7.7 5.4 13.9 5.0 6.7 5.3 5.7 12.3 4.9 3.8 4.5 6.9 3.0 9.4 6.0 7.1 5.2 18.3 20.6 28.7 25.6 18.3 14.8 13.4 14.7 12.8 10.6 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828599-49856574 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavourable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 4.8 1.6 3.4 6.0 10.7 9.5 3.0 7.4 3.0 3.5 3.7 2.0 3.2 2.3 3.8 2.4 4.5 3.0 2.9 1.5 2.7 2.7 1.6 1.2 1.3 8.1 2.0 2.8 3.4 1.6 1.6 2.0 2.5 3.0 2.9 4.8 2.7 3.1 1.7 2.8 6.7 3.4 3.4 5.1 3.7 1.9 25.0 3.4 11.5 2.2 3.1 6.8 1.9 3.0 5.1 1.6 0.6 3.0 2.7 4.9 1.6 6.4 7.9 11.3 11.3 1.0 1.6 9.3 7.8 3.7 16.5 15.8 9.5 7.4 15.9 5.5 4.5 8.5 11.8 8.9 12.4 9.1 7.8 11.9 9.6 8.5 0.4 9.7 10.0 1.1 1.3 13.2 7.0 4.3 8.6 11.5 7.3 9.3 16.1 12.4 9.0 13.0 8.9 7.6 9.2 3.0 9.0 5.5 9.4 8.6 7.3 5.5 6.6 13.9 3.3 10.6 12.6 14.5 15.2 8.5 20.2 17.0 5.3 13.2 9.4 0.0 1.5 0.6 2.3 0.8 2.0 5.1 1.3 4.9 1.3 3.8 1.7 2.6 0.3 2.7 3.0 1.6 0.8 1.6 3.4 10.7 7.4 3.0 2.7 2.7 2.0 2.8 3.0 3.4 TRDMT1 "DNMT2, RNMT1" ENSG00000107614 "TRNA aspartic acid methyltransferase 1" O14717 10 17142254-17202054 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009468, HPA036945, HPA036946" Approved Approved Nucleoplasm,Nucleoli,Centrosome Nucleoli "Nucleoplasm, Centrosome" "CAB009468: AB_2208432, HPA036945: , HPA036946: " "unprognostic (4.55e-1)" "unprognostic (3.22e-2)" "unprognostic (4.49e-6)" "unprognostic (7.07e-2)" "unprognostic (3.87e-3)" "unprognostic (1.33e-1)" "unprognostic (3.27e-4)" "unprognostic (3.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (3.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (2.64e-2)" 6.1 4.4 4.4 8.5 7.7 4.0 6.3 14.0 6.2 5.3 3.8 4.2 4.7 4.1 7.5 14.4 3.9 6.8 5.1 5.0 4.9 4.5 6.7 2.7 5.3 5.3 4.3 2.9 9.6 5.0 12.8 12.6 5.1 6.2 5.0 3.6 8.0 5.6 3.8 4.3 4.4 5.0 5.4 5.1 5.9 4.2 4.2 6.1 19.9 11.5 3.3 5.7 4.0 5.2 6.1 10.5 5.2 4.4 3.5 8.0 3.6 5.1 2.5 10.0 2.6 3.8 2.2 0.0 4.4 3.2 4.7 5.5 4.2 4.3 3.5 0.6 5.0 2.6 6.7 4.2 5.4 7.4 4.3 5.2 3.8 2.5 3.4 3.4 3.9 3.0 2.6 3.2 2.3 6.1 6.5 3.9 7.7 1.6 17.0 0.8 6.3 2.9 3.7 7.8 2.2 2.5 2.8 2.7 3.4 0.0 1.9 3.4 4.8 3.1 3.6 3.4 7.2 6.3 5.1 5.0 4.7 8.9 4.3 4.8 3.4 5.2 4.4 2.4 3.9 2.5 7.2 5.4 6.6 4.9 5.5 6.1 8.0 5.8 2.8 3.5 1.4 10.5 2.2 3.6 4.4 7.7 14.0 6.2 4.9 4.5 4.3 2.9 6.2 6.1 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: " "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavourable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 8.8 9.2 8.9 13.8 16.5 33.2 23.8 45.2 11.5 8.7 11.2 6.4 15.1 10.1 8.7 10.6 13.3 9.4 13.9 6.9 9.2 8.5 7.7 7.1 27.5 18.6 9.0 8.0 9.0 11.9 8.5 7.2 9.4 7.1 10.5 9.7 6.0 14.4 18.2 5.0 12.5 11.8 8.6 6.0 16.5 12.6 9.5 7.8 20.0 9.0 9.7 13.1 9.5 24.3 6.4 6.9 10.0 11.4 9.4 11.8 5.4 13.8 13.2 7.1 9.7 5.3 4.4 33.5 9.1 6.1 10.6 8.5 16.0 12.1 10.4 10.2 6.1 22.6 8.5 8.7 4.5 11.6 20.5 8.6 12.2 8.6 14.5 10.9 13.2 5.9 14.0 10.9 5.5 5.2 19.7 13.5 5.4 9.0 13.1 17.2 18.1 11.7 12.9 6.4 12.6 6.9 17.0 11.8 21.7 7.6 21.6 12.0 15.2 18.2 5.8 6.7 9.5 15.7 18.8 13.9 9.2 9.2 8.4 8.7 10.6 6.1 6.9 8.3 9.6 8.2 10.2 5.8 10.7 11.8 6.9 6.4 6.3 8.4 10.0 9.4 11.4 5.5 9.8 5.4 8.9 16.5 45.2 11.5 9.2 8.5 9.0 8.0 7.1 7.8 TRIM13 "DLEU5, Leu5, RFP2, RNF77" ENSG00000204977 "Tripartite motif containing 13" O60858 13 49995888-50020481 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000367 Enhanced "HPA000367: AB_1856196" "unprognostic (1.14e-1)" "unprognostic (8.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.23e-3)" "unprognostic (4.75e-3)" "unprognostic (5.01e-2)" "unprognostic (4.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.44e-1)" "unprognostic (5.07e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-2)" "unprognostic (9.01e-2)" "unprognostic (2.37e-2)" "unprognostic (1.55e-2)" 13.2 9.8 9.9 11.9 11.4 37.5 19.6 18.5 13.5 13.1 11.7 12.3 15.2 8.6 13.9 10.7 18.8 12.2 8.7 12.4 10.1 9.2 16.6 9.9 14.7 12.4 12.2 8.0 13.8 14.0 10.8 14.4 10.0 11.5 14.5 14.0 9.6 16.2 15.6 16.3 18.2 13.0 10.4 10.8 15.3 10.6 49.0 12.1 25.1 17.3 13.9 15.5 13.0 12.9 28.4 20.6 21.6 13.0 15.4 17.2 8.4 5.1 6.0 20.9 16.1 11.8 18.5 9.5 8.5 12.3 6.9 4.8 8.3 11.8 19.1 2.6 9.2 8.1 9.2 11.2 8.5 7.3 8.1 18.9 4.6 9.2 13.2 18.1 11.1 13.5 16.5 6.3 10.5 15.2 10.0 6.1 13.5 4.6 15.0 28.4 18.9 4.5 18.3 0.9 5.7 14.6 8.5 8.4 13.8 7.7 8.0 11.8 9.0 23.0 14.1 7.1 6.6 5.8 4.7 4.4 3.6 14.0 3.2 8.3 9.6 12.1 10.8 16.1 12.2 9.3 15.3 28.2 16.5 15.9 13.5 28.4 14.6 13.6 21.6 15.4 13.0 20.6 17.2 8.4 9.9 11.4 18.5 13.5 10.1 9.2 12.2 8.0 11.5 12.1 TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407940-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8;testis: 18.3" "Cell line enhanced" "Detected in some" "BEWO: 7.6;HEL: 3.5;NTERA-2: 3.2;SH-SY5Y: 4.0;T-47d: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054908 Uncertain Approved Vesicles Vesicles "HPA054908: " "prognostic favourable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" 1.3 0.8 14.4 1.5 19.1 1.1 1.9 25.8 11.8 1.5 0.9 0.6 1.7 1.4 3.6 1.7 1.3 3.9 1.7 1.5 8.9 3.4 1.2 0.6 1.7 2.0 0.7 9.2 2.2 1.1 0.8 1.0 1.3 2.7 2.0 0.8 1.9 5.9 3.8 0.8 3.5 1.6 1.1 0.9 5.3 1.4 18.3 4.7 0.0 2.9 0.1 1.2 2.5 1.3 1.7 0.6 0.7 0.3 0.0 1.0 0.1 0.3 0.6 0.4 0.4 0.0 0.0 7.6 0.5 0.0 0.0 0.1 1.7 0.9 0.1 1.9 0.0 1.7 0.0 0.0 0.1 0.3 0.7 3.5 1.0 0.2 1.6 0.1 0.3 0.2 0.2 0.1 0.0 0.0 0.2 0.5 0.1 0.1 0.3 0.0 3.2 0.2 0.1 0.1 0.0 0.0 0.8 0.5 4.0 0.0 0.4 0.0 9.4 0.2 0.0 0.3 1.7 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.7 0.9 0.1 1.0 0.6 0.2 1.0 0.0 1.7 1.0 0.8 0.2 0.0 0.2 0.6 0.0 0.1 14.4 19.1 25.8 11.8 8.9 3.4 0.7 9.2 2.7 4.7 TRIM2 "CMT2R, KIAA0517, RNF86" ENSG00000109654 "Tripartite motif containing 2" Q9C040 4 153152342-153339320 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.0" "Cell line enhanced" "Detected in many" "AF22: 28.1;NTERA-2: 23.1;RPTEC TERT1: 26.3;SK-MEL-30: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD4 T-cell: 5.4" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035853, HPA035854" Enhanced Approved Centrosome Centrosome "HPA035853: AB_10669533, HPA035854: AB_10669659" "unprognostic (8.94e-2)" "unprognostic (7.89e-2)" "unprognostic (6.21e-3)" "unprognostic (7.51e-3)" "unprognostic (2.07e-2)" "unprognostic (2.32e-1)" "unprognostic (1.16e-2)" "unprognostic (2.30e-3)" "unprognostic (5.30e-2)" "unprognostic (6.77e-2)" "unprognostic (1.93e-2)" "unprognostic (1.42e-2)" "prognostic favourable (6.58e-14)" "unprognostic (5.89e-2)" "unprognostic (1.17e-2)" "unprognostic (4.19e-2)" "unprognostic (4.13e-2)" 4.2 9.9 28.4 4.4 35.7 0.6 12.2 28.9 56.9 19.6 17.8 67.0 5.9 13.5 9.7 15.1 8.5 12.9 10.3 6.2 38.9 25.3 22.1 6.4 5.9 2.3 39.4 34.6 10.9 8.2 1.0 10.9 2.5 45.3 11.5 19.2 4.6 30.1 11.8 1.8 3.8 14.4 6.6 44.2 8.8 23.5 1.9 44.7 0.0 38.9 0.6 4.3 7.6 5.5 1.9 0.8 0.3 0.6 0.3 5.4 0.7 4.7 0.2 28.1 12.3 10.6 12.2 0.4 6.3 8.6 1.8 2.6 2.7 0.3 0.2 4.0 10.9 4.3 13.1 2.4 1.8 0.1 4.9 0.2 2.9 0.6 12.4 0.2 0.1 7.9 1.4 3.6 2.3 1.6 0.2 0.1 2.2 0.4 1.3 0.0 23.1 5.6 0.8 5.1 0.0 26.3 6.2 9.1 17.9 3.0 11.4 25.2 1.2 0.2 2.4 7.9 2.3 6.1 3.0 0.1 0.0 0.1 11.8 0.1 9.7 0.3 0.6 0.1 0.1 0.0 0.0 1.6 5.4 0.1 0.8 1.9 1.6 1.0 0.2 0.3 0.0 0.1 2.6 0.7 28.4 35.7 28.9 41.1 38.9 25.3 39.4 34.6 45.3 44.7 TRIM21 "RNF81, Ro/SSA, RO52, SSA1" ENSG00000132109 "Tripartite motif containing 21" P19474 11 4384897-4393696 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 72.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004566, HPA005673" Approved Approved Nucleoplasm Nucleoplasm "CAB004566: AB_628286, HPA005673: AB_1080090" "prognostic favourable (4.83e-5)" "unprognostic (4.55e-2)" "unprognostic (3.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (1.87e-4)" "unprognostic (1.20e-1)" "unprognostic (5.04e-2)" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (3.31e-1)" "unprognostic (1.82e-2)" "unprognostic (6.27e-2)" "unprognostic (4.69e-2)" "prognostic favourable (2.26e-6)" "unprognostic (9.12e-3)" 18.2 12.1 4.9 13.7 6.5 15.0 9.8 2.5 6.4 15.0 11.7 6.4 6.0 12.5 11.6 10.3 14.6 10.4 10.8 8.5 5.0 5.3 12.9 14.9 14.6 21.4 6.8 4.0 17.4 10.7 4.3 9.9 19.9 8.6 18.0 12.0 8.5 11.9 8.6 4.5 6.9 21.8 12.0 4.7 28.3 13.5 6.0 4.7 21.5 19.1 6.8 17.0 11.6 13.5 10.9 22.0 72.4 27.5 14.5 19.5 28.6 5.9 7.0 3.5 3.3 7.3 11.0 4.9 7.6 14.4 30.2 33.5 3.2 17.2 9.1 3.5 11.2 8.5 6.2 11.6 9.4 15.2 6.9 14.0 4.0 2.8 16.2 16.5 13.9 10.7 7.0 6.1 4.2 18.4 4.4 10.0 10.0 5.2 8.6 12.1 3.0 3.6 6.1 4.6 5.0 11.9 5.5 0.0 1.5 6.2 7.0 8.4 2.4 11.3 16.5 7.4 5.8 3.8 2.8 5.3 4.1 5.8 6.6 13.1 5.2 18.8 26.9 60.1 19.3 27.5 16.8 10.5 16.6 17.1 22.0 10.9 14.9 15.7 72.4 14.5 24.4 7.4 19.5 28.6 4.9 6.5 2.5 6.4 5.0 5.3 6.8 4.0 8.6 4.7 TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689689-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.3;BJ hTERT+ SV40 Large T+ RasG12V: 47.9;HSkMC: 42.0;TIME: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA003307: AB_1080381, HPA003575: AB_1080378" "unprognostic (1.47e-2)" "unprognostic (5.27e-3)" "unprognostic (4.00e-2)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-3)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" "unprognostic (1.15e-1)" "unprognostic (9.16e-2)" 34.3 6.9 8.8 32.8 13.3 22.2 17.3 3.2 10.3 14.4 12.2 10.6 15.1 6.5 20.0 18.9 17.6 17.2 20.2 12.4 10.3 6.6 13.9 19.3 29.8 62.2 15.5 6.5 21.9 5.6 2.1 8.1 9.4 13.3 20.4 13.7 15.0 17.2 14.6 7.1 7.8 28.7 13.5 22.9 65.4 11.2 6.3 12.0 35.6 15.5 13.4 40.6 19.8 13.5 49.0 55.2 33.0 50.3 18.0 58.1 47.3 0.8 0.2 3.4 0.6 18.5 37.3 1.0 10.9 19.1 20.8 47.9 0.3 2.2 23.0 3.3 15.4 2.3 7.6 11.4 2.0 0.5 0.0 1.3 1.2 0.4 24.3 3.5 2.2 42.0 10.8 4.1 1.9 25.6 0.5 1.2 22.6 0.4 12.0 3.6 9.8 1.2 14.9 0.8 0.5 10.9 3.5 0.4 0.8 1.0 1.0 0.4 1.2 3.9 33.4 12.9 7.0 0.6 0.6 1.3 1.1 2.5 16.2 6.4 1.7 27.4 35.7 23.8 35.8 43.5 47.0 46.5 39.0 37.8 42.8 49.0 35.2 33.7 33.0 18.0 50.3 55.2 58.1 47.3 8.8 13.3 3.2 10.3 10.3 6.6 15.5 6.5 13.3 12.0 TRIM23 "ARD1, ARFD1, RNF46" ENSG00000113595 "Tripartite motif containing 23" P36406 5 65589680-65625975 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039605 Approved "HPA039605: AB_10673146" "unprognostic (4.06e-1)" "unprognostic (1.07e-1)" "unprognostic (5.11e-2)" "unprognostic (3.63e-1)" "unprognostic (7.96e-2)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (5.00e-3)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (3.19e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.62e-1)" "unprognostic (6.55e-3)" "unprognostic (2.70e-1)" 8.6 12.7 15.0 6.6 17.9 7.6 9.4 25.8 34.3 11.5 7.8 9.5 7.3 4.5 10.6 7.0 9.0 8.6 6.3 12.3 16.3 15.2 10.2 11.8 6.6 7.7 14.4 18.8 16.2 6.5 11.1 11.6 7.9 22.1 12.9 5.3 4.1 5.7 9.4 14.8 6.6 5.2 9.3 14.2 8.2 5.6 10.9 14.0 7.5 12.4 4.4 7.6 7.5 7.6 6.0 3.8 14.5 4.5 5.6 9.9 4.5 6.3 8.7 9.3 14.0 14.5 14.6 7.0 12.1 11.6 10.4 12.8 8.0 6.1 4.9 14.6 8.5 5.1 9.1 7.1 16.1 5.1 9.6 3.9 11.9 5.0 13.5 2.4 5.5 11.4 6.0 11.6 10.5 5.0 4.5 7.0 12.2 5.9 5.0 2.7 5.1 3.6 4.7 16.9 7.0 5.4 6.5 5.5 7.7 11.6 3.5 9.6 7.6 3.3 8.5 8.1 8.7 10.1 8.9 8.7 8.0 6.0 9.5 4.7 8.1 14.5 4.0 9.5 5.6 3.0 6.9 4.7 6.1 4.9 3.6 6.0 9.9 7.5 10.1 5.6 4.5 3.8 6.9 4.5 15.0 17.9 25.8 31.1 16.3 15.2 14.4 18.8 22.1 14.0 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460334-138589993 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 42.7;HMC-1: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (9.94e-4)" "prognostic favourable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 10.3 31.4 10.4 11.2 10.6 8.8 8.8 8.5 10.7 9.4 9.2 14.6 5.7 9.4 9.0 8.5 11.3 7.0 10.3 9.7 8.4 8.5 9.6 21.5 10.7 8.5 10.5 8.0 29.9 11.6 20.7 7.3 13.5 8.4 13.6 9.1 7.5 10.1 7.1 16.0 9.8 14.1 9.4 8.0 8.5 10.8 24.1 11.3 34.8 8.8 9.2 8.9 11.3 11.2 1.3 1.9 3.7 2.5 2.2 2.7 0.8 4.1 5.1 42.7 12.3 2.9 2.6 3.3 3.9 4.1 3.0 3.0 8.1 3.9 8.0 3.9 3.7 2.2 20.7 3.2 4.5 6.1 5.1 17.7 3.8 24.9 3.9 13.7 57.8 2.3 3.4 2.5 4.1 7.2 20.0 4.9 3.6 8.1 23.4 12.5 16.3 4.6 18.6 5.0 6.8 6.8 12.5 8.9 20.2 7.3 6.5 2.1 4.5 9.1 3.0 3.5 2.9 6.2 5.3 4.6 4.9 13.7 5.9 9.1 5.2 1.1 2.3 3.6 2.2 2.5 0.4 0.9 1.9 1.2 1.9 1.3 1.8 2.0 3.7 2.2 1.1 1.4 2.7 0.8 10.4 10.6 8.5 9.7 8.4 8.5 10.5 8.0 8.4 11.3 TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56887909-56914038 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 20.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" 35000 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: AB_1078722" "unprognostic (8.73e-3)" "unprognostic (1.57e-2)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "prognostic unfavourable (9.37e-4)" "unprognostic (1.53e-1)" "unprognostic (4.23e-1)" "unprognostic (1.15e-1)" "prognostic favourable (3.36e-4)" "unprognostic (3.23e-1)" "unprognostic (3.11e-2)" "prognostic favourable (9.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.13e-2)" "unprognostic (7.39e-2)" 20.0 19.7 7.5 23.6 8.9 32.6 19.3 11.6 7.8 15.3 22.5 5.0 8.0 15.3 13.4 12.6 17.7 15.3 18.4 8.3 5.8 6.3 10.1 27.0 20.8 15.9 6.7 5.5 13.3 15.3 13.6 11.5 55.0 7.4 12.2 14.3 12.5 14.5 11.5 11.7 23.1 20.7 10.1 5.2 35.8 14.1 12.8 6.5 26.2 11.8 15.1 18.5 10.6 35.9 1.7 2.4 20.0 2.3 0.8 1.5 0.7 28.8 14.3 3.5 11.9 26.7 22.6 0.0 11.4 23.1 27.3 23.6 13.9 15.9 28.2 23.7 10.9 17.2 17.2 15.3 15.3 24.0 13.6 18.2 11.1 15.4 23.0 21.7 13.1 10.1 25.8 14.2 30.3 18.1 4.4 17.3 13.8 19.3 24.2 15.7 2.2 27.8 17.4 11.9 17.7 15.9 22.8 6.9 6.4 9.0 14.5 26.5 19.6 17.7 12.0 12.8 9.2 19.6 11.8 9.8 18.7 4.7 12.4 15.0 5.0 3.0 2.3 0.9 0.9 1.9 1.1 1.7 0.8 0.8 2.4 1.4 0.6 0.8 20.0 0.8 1.4 1.7 1.5 0.7 7.5 8.9 11.6 7.8 5.8 6.3 6.7 5.5 7.4 6.5 TRIM26 "RNF95, ZNF173" ENSG00000234127 "Tripartite motif containing 26" Q12899 6 30184455-30213427 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044975, HPA050456" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA044975: , HPA050456: " "unprognostic (1.93e-1)" "unprognostic (5.41e-2)" "unprognostic (8.53e-2)" "unprognostic (1.96e-3)" "unprognostic (1.52e-1)" "unprognostic (5.50e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-2)" "unprognostic (2.85e-1)" "unprognostic (3.08e-2)" "unprognostic (1.97e-1)" "unprognostic (7.00e-3)" "unprognostic (1.37e-2)" "unprognostic (1.63e-3)" "unprognostic (5.21e-2)" "unprognostic (8.82e-2)" "prognostic favourable (3.25e-5)" 11.9 12.6 10.6 20.0 12.2 13.8 13.2 17.6 14.9 10.7 16.1 15.9 14.5 18.5 12.9 18.4 21.5 21.1 18.6 8.4 10.8 11.3 19.5 19.2 12.2 21.3 13.1 8.1 10.9 15.3 16.3 11.5 10.8 12.3 13.4 9.8 17.7 18.4 20.6 9.9 21.5 21.9 14.2 13.1 17.6 15.2 10.9 14.0 13.7 15.8 10.7 21.7 14.7 24.6 3.6 3.8 1.7 4.2 2.1 4.1 3.6 10.2 2.2 0.0 14.5 4.8 2.8 4.7 2.8 3.3 7.2 7.2 0.0 0.4 22.9 8.2 7.1 11.7 0.0 10.0 2.3 0.0 6.7 3.5 1.6 8.3 4.5 4.5 2.9 3.0 3.5 7.3 4.6 4.5 1.6 0.0 0.0 0.0 7.5 11.1 0.0 3.9 9.9 6.9 3.3 6.0 9.6 0.4 6.2 10.5 4.6 2.9 3.6 1.5 7.5 5.6 3.9 0.0 0.1 9.2 16.4 12.1 0.0 13.0 8.9 1.7 3.1 0.5 3.9 4.2 3.2 3.2 2.9 3.8 3.8 3.6 1.8 2.7 1.7 2.1 2.6 1.9 4.1 3.6 10.6 12.2 17.6 14.9 10.8 11.3 13.1 8.1 12.3 14.0 TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923989 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA048684: , HPA053408: " "unprognostic (1.57e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.01e-2)" "unprognostic (1.12e-3)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "prognostic unfavourable (3.50e-6)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "prognostic favourable (2.71e-4)" 11.5 10.6 8.8 25.5 9.7 7.9 9.3 10.1 12.2 11.2 10.2 8.7 20.2 23.8 12.1 13.2 7.8 12.1 11.4 8.1 8.2 9.6 10.1 22.5 10.4 17.4 12.6 8.3 14.7 31.0 7.4 13.9 13.7 10.6 13.7 4.6 7.7 17.0 25.2 12.2 9.7 19.4 9.2 8.4 18.6 18.5 9.2 9.2 16.7 12.5 7.9 12.1 9.9 11.8 12.5 12.5 13.8 13.9 11.2 15.9 13.8 3.3 2.3 0.9 6.0 0.8 1.7 0.6 4.6 1.1 1.4 1.7 1.7 1.4 7.7 7.9 1.3 7.4 1.1 2.7 0.1 3.0 12.9 10.8 0.5 2.3 1.3 4.5 1.7 1.3 1.6 1.2 0.5 1.2 10.5 3.3 0.4 1.3 6.3 2.4 0.0 7.3 9.0 6.9 14.2 1.1 1.1 3.2 12.9 5.5 3.4 7.3 3.3 3.5 3.9 3.4 7.1 6.2 2.7 12.0 14.4 12.0 1.8 11.5 5.2 12.6 13.8 8.8 12.7 13.9 15.9 12.5 12.6 14.4 12.5 10.5 11.8 12.1 13.8 11.2 12.1 9.8 10.4 13.8 8.8 9.7 10.1 12.2 8.2 9.6 12.6 8.3 10.6 9.2 TRIM28 "KAP1, PPP1R157, RNF96, TF1B, TIF1B" ENSG00000130726 "Tripartite motif containing 28" Q13263 19 58544091-58550722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 217.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010066, HPA064033" Supported Enhanced Nucleoplasm "Intracellular and membrane" 140000 Nucleoplasm "CAB010066: AB_2209905, HPA064033: " "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (2.99e-1)" "prognostic unfavourable (1.85e-6)" "unprognostic (1.20e-2)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (4.92e-3)" "unprognostic (9.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.67e-2)" "unprognostic (7.34e-2)" "unprognostic (4.22e-1)" "unprognostic (3.28e-2)" 24.2 26.4 17.9 40.1 20.6 52.2 30.6 34.5 26.3 46.7 36.5 26.2 26.2 26.8 43.3 30.0 34.1 34.5 38.5 28.4 18.5 16.4 27.3 42.3 29.5 38.1 29.2 22.7 69.3 47.0 30.7 25.7 45.6 22.8 37.6 18.5 21.5 31.8 32.4 56.5 41.2 27.5 38.4 17.9 34.9 32.9 48.1 23.1 119.9 50.6 33.5 33.5 34.0 46.4 13.7 14.6 5.0 7.6 16.0 16.9 6.3 35.8 77.2 41.5 30.6 18.1 13.9 46.3 23.6 21.4 23.0 17.6 53.8 30.2 39.5 15.6 20.3 24.6 46.9 33.9 15.1 20.2 217.0 67.9 35.0 42.7 19.3 43.0 43.7 18.8 18.9 29.4 23.1 21.5 33.0 22.3 21.2 53.1 60.1 53.1 29.1 49.8 57.1 25.1 42.4 20.6 59.6 41.6 32.6 24.6 32.0 13.1 22.0 41.9 19.8 54.2 21.5 11.8 42.2 28.7 46.8 44.1 24.5 32.2 34.3 1.3 7.1 5.0 8.9 7.6 11.6 11.5 12.8 12.3 9.0 13.7 16.9 15.1 3.8 16.0 4.9 14.6 8.2 6.3 17.9 20.6 34.5 26.3 18.5 16.4 29.2 22.7 22.8 23.1 TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113106 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.3;lymphoid tissue: 7.4;urinary bladder: 12.2" "Cell line enriched" "Detected in single" 490 "RT4: 79.5" "Group enriched" "Detected in many" 5 "cervical cancer: 6.7;colorectal cancer: 25.8;pancreatic cancer: 11.4;stomach cancer: 19.8;urothelial cancer: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046400 Uncertain "HPA046400: " "unprognostic (1.37e-1)" "unprognostic (7.78e-3)" "unprognostic (1.83e-1)" "unprognostic (7.05e-3)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (6.13e-2)" "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" 0.1 0.0 0.1 7.4 0.1 0.0 0.1 0.1 0.1 0.2 16.3 0.1 0.1 1.2 0.1 0.1 0.1 0.1 3.3 0.1 0.1 0.0 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 2.1 0.4 0.1 0.1 0.1 0.1 0.1 13.7 0.7 0.1 0.1 4.8 2.0 0.1 0.1 0.1 0.1 0.1 12.2 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687302-116701300 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease mutation, Limb-girdle muscular dystrophy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" "Intermediate filaments" "HPA050060: " "unprognostic (2.47e-2)" "unprognostic (7.06e-3)" "unprognostic (5.50e-2)" "unprognostic (3.63e-1)" "unprognostic (5.08e-2)" "prognostic unfavourable (4.53e-4)" "prognostic unfavourable (4.72e-4)" "unprognostic (2.41e-3)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (6.03e-2)" "unprognostic (7.06e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-3)" "unprognostic (9.77e-2)" 9.5 9.1 6.6 5.8 11.5 0.8 8.0 23.2 17.1 12.8 7.9 7.2 6.2 6.7 17.0 8.0 8.8 15.9 8.2 8.9 5.7 7.3 6.2 5.0 6.3 8.4 5.7 9.8 12.6 12.5 12.2 7.7 7.0 9.1 10.3 7.4 10.4 10.9 9.2 23.9 6.6 8.9 12.9 5.3 6.9 6.8 6.5 2.2 9.4 8.4 6.2 8.3 11.1 8.8 6.1 3.5 0.2 2.6 5.6 16.0 4.7 6.4 14.9 8.8 9.7 17.9 12.9 6.7 12.1 13.3 13.8 11.6 9.9 7.1 6.7 5.4 18.5 13.9 10.7 13.6 12.6 5.9 5.2 3.6 9.6 6.0 9.3 2.4 11.9 11.0 12.3 13.0 7.7 8.9 5.0 5.7 16.1 8.3 6.4 0.0 8.0 9.0 7.6 23.7 4.4 5.6 15.2 8.8 4.5 9.5 6.6 6.9 18.4 2.4 11.0 12.8 10.3 9.4 9.1 9.4 2.5 10.5 10.7 1.6 12.5 0.0 1.3 0.0 9.3 2.6 7.2 6.1 8.2 7.4 1.8 4.4 8.3 8.4 0.2 5.6 2.1 3.5 16.0 4.7 6.6 11.5 23.2 17.1 5.7 7.3 5.7 9.8 9.1 2.2 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392777-114511160 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favourable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favourable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 15.2 12.8 16.9 18.4 19.9 27.1 17.1 38.3 21.8 16.9 14.3 11.0 21.9 10.9 19.8 38.3 16.4 15.0 15.6 10.8 18.1 12.5 17.3 15.0 14.3 15.2 12.1 18.0 19.8 15.7 21.8 22.4 27.2 15.2 16.5 13.0 10.7 16.4 19.1 14.3 19.5 14.8 20.2 12.9 14.9 14.1 29.0 16.3 20.5 17.9 9.8 16.6 17.9 28.7 3.4 4.0 12.2 2.8 4.7 4.4 1.0 12.9 7.0 13.2 9.9 5.6 5.9 22.5 6.6 7.0 9.2 9.8 7.9 5.5 13.8 6.8 7.7 7.5 12.0 7.7 12.7 10.4 7.1 13.3 9.2 9.1 6.2 16.8 11.1 5.6 5.7 10.9 11.2 7.7 16.6 9.8 8.8 48.5 16.9 7.1 17.8 7.1 14.6 20.2 4.5 6.6 20.4 9.2 9.7 12.5 15.1 11.9 6.9 9.2 8.6 6.4 10.5 14.8 9.2 6.9 6.4 14.5 9.1 9.8 18.2 12.2 1.6 7.4 3.5 1.8 3.1 3.4 3.7 3.7 2.0 2.2 2.9 4.4 4.8 4.7 2.8 4.0 2.0 1.0 16.9 19.9 38.3 21.8 18.1 12.5 12.1 18.0 15.2 16.3 TRIM36 "HAPRIN, RBCC728, RNF98" ENSG00000152503 "Tripartite motif containing 36" Q9NQ86 5 115124762-115180546 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 88.8" "Cell line enhanced" "Detected in many" "RH-30: 17.8;SCLC-21H: 19.9;SH-SY5Y: 14.5" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "myeloid DC: 7.5;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 43 "dendritic cells: 7.5;granulocytes: 4.2;monocytes: 7.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061321 Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA061321: " "unprognostic (6.36e-2)" "unprognostic (2.99e-1)" "unprognostic (4.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.31e-2)" "unprognostic (5.33e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (2.82e-13)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (6.80e-3)" 1.0 1.4 6.8 1.4 7.6 0.8 3.2 0.6 11.7 1.4 4.8 7.7 0.0 8.2 1.1 1.0 0.8 1.9 1.0 0.7 10.1 7.2 0.9 0.9 1.6 0.8 7.1 8.6 3.5 1.5 0.7 8.2 1.3 18.3 5.7 4.8 5.1 1.0 1.0 0.7 1.0 7.9 1.1 8.7 0.9 2.0 88.8 4.7 0.0 0.8 0.0 0.9 0.8 1.0 0.1 7.5 4.2 7.7 0.0 0.0 0.8 2.4 0.7 1.2 6.2 0.1 0.1 1.5 0.5 2.1 1.1 1.3 0.9 1.2 0.0 1.0 0.1 0.6 5.8 1.1 0.8 0.4 1.9 4.3 2.5 1.2 0.2 4.2 3.6 0.1 1.1 0.5 1.5 0.0 0.1 5.9 1.7 3.3 1.1 3.8 4.9 2.8 0.9 17.8 1.4 0.6 0.0 19.9 14.5 3.8 0.4 2.3 4.2 5.3 0.5 1.7 1.3 1.3 1.9 0.9 0.5 0.0 1.9 2.4 0.8 0.0 1.7 4.2 0.0 1.6 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.3 0.0 7.7 1.6 0.0 0.8 6.8 7.6 0.6 11.7 10.1 7.2 7.1 8.6 18.3 4.7 TRIM37 "KIAA0898, MUL, POB1, TEF3" ENSG00000108395 "Tripartite motif containing 37" O94972 17 58982638-59106921 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Repressor, Transferase" "Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.1" "Cell line enriched" "Detected in all" 4 "MCF7: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 20.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021911 Uncertain "HPA021911: AB_10964487" "unprognostic (4.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavourable (4.99e-6)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-3)" "unprognostic (4.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.46e-1)" "unprognostic (4.27e-2)" "unprognostic (3.04e-2)" 6.7 10.3 17.4 7.1 24.4 5.1 7.1 33.4 33.9 7.2 5.9 7.9 4.9 5.2 7.4 9.2 7.1 8.2 7.5 9.1 19.0 19.5 6.5 6.5 7.4 6.8 17.7 18.1 5.5 6.5 6.1 8.9 7.7 32.4 8.1 6.2 5.8 4.4 8.1 7.9 6.1 4.6 8.9 8.7 6.4 5.3 46.1 7.4 6.8 11.1 2.1 6.7 6.8 4.4 3.8 3.4 20.0 3.1 2.9 6.5 2.5 6.8 10.0 6.9 9.1 6.8 6.2 11.1 7.5 11.7 8.2 13.5 6.1 4.7 6.4 11.5 7.8 5.9 10.0 5.6 13.1 12.7 9.7 9.9 9.5 8.4 12.0 5.1 5.3 5.0 5.4 10.2 13.3 10.5 7.7 9.5 8.1 75.3 10.3 3.0 10.1 6.7 4.6 18.2 4.5 7.8 8.8 16.8 9.9 7.8 3.3 7.3 9.7 2.4 8.1 12.9 15.4 11.7 8.5 9.6 14.1 5.7 8.8 5.5 6.0 20.0 3.1 3.6 6.3 2.4 5.9 3.2 4.1 4.1 3.4 3.8 3.7 4.7 4.5 2.9 2.3 2.6 6.5 2.5 17.4 24.4 33.4 33.9 19.0 19.5 17.7 18.1 32.4 7.4 TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991226 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favourable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favourable (8.20e-5)" "prognostic favourable (4.94e-9)" 13.3 8.4 2.5 15.7 2.3 12.0 7.9 1.1 3.4 17.2 12.1 3.1 20.5 6.7 26.2 22.3 15.7 8.9 9.2 5.8 2.8 2.3 26.1 8.8 14.0 14.4 3.7 1.8 11.5 4.3 1.0 4.3 10.3 3.5 15.5 7.8 9.2 9.8 16.5 9.0 5.3 14.6 13.1 4.5 17.6 6.6 5.3 2.9 16.6 13.7 9.5 20.1 18.0 15.4 16.5 10.1 12.1 12.9 6.7 7.9 6.3 3.5 2.0 0.3 4.3 10.3 13.9 3.6 4.5 8.9 8.7 14.5 1.5 3.8 7.9 7.4 5.5 5.6 2.7 4.4 5.2 7.9 1.8 3.5 3.3 1.4 13.7 4.2 7.4 13.8 3.2 5.4 1.9 7.5 2.3 4.4 10.3 1.7 4.0 4.8 1.4 2.7 6.2 4.3 8.2 10.4 7.0 0.1 0.1 3.4 7.1 12.0 1.0 5.5 7.7 1.6 2.7 2.7 3.0 5.1 3.7 8.9 4.2 5.2 9.6 10.1 10.6 4.7 7.6 12.9 7.4 14.3 6.5 6.8 10.1 16.5 6.2 6.7 12.1 6.7 11.4 9.5 7.9 6.3 2.5 2.3 1.1 3.4 2.8 2.3 3.7 1.8 3.5 2.9 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol Cytosol "HPA051120: , HPA059496: " "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favourable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 8.6 7.6 5.2 14.3 6.4 11.8 7.4 8.6 7.6 10.2 11.2 7.3 9.7 7.1 10.0 15.2 11.9 8.5 13.6 6.1 5.4 5.5 7.6 9.6 11.1 6.7 7.7 6.3 10.3 9.1 8.9 11.4 11.6 7.1 7.9 7.1 11.4 8.2 15.5 9.9 6.5 10.9 8.8 6.0 13.1 8.0 14.1 7.2 7.8 8.9 8.3 10.1 9.1 12.3 3.4 1.6 8.4 2.5 4.4 5.2 2.1 4.4 0.2 3.8 6.8 1.8 1.8 3.9 2.0 2.5 3.0 2.7 5.3 0.6 5.6 4.1 3.8 1.4 4.4 3.1 3.1 4.4 4.8 4.5 0.7 1.9 3.9 6.6 5.0 2.1 2.6 3.8 4.2 1.9 6.6 4.5 3.9 4.0 1.4 1.4 5.1 3.2 3.1 0.8 4.2 3.3 4.3 8.3 4.1 1.6 3.3 3.9 4.4 1.7 1.7 3.3 2.7 4.0 6.8 8.2 10.0 5.8 2.0 2.4 5.1 1.4 1.7 6.8 5.2 2.5 4.6 3.4 3.7 3.8 1.6 3.3 4.4 4.1 8.4 4.4 2.4 1.2 2.9 2.1 5.2 6.4 8.6 7.6 5.4 5.5 7.7 6.3 7.1 7.2 TRIM4 RNF87 ENSG00000146833 "Tripartite motif containing 4" Q9C037 7 99876958-99919600 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019356, HPA029461" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA019356: AB_1856376, HPA029461: AB_10600834" "unprognostic (1.88e-1)" "unprognostic (2.97e-2)" "unprognostic (3.37e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-2)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (5.42e-2)" "unprognostic (3.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.48e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.36e-6)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (5.65e-2)" 19.1 22.6 13.5 22.1 15.9 6.7 22.1 20.1 15.5 19.5 17.3 12.4 22.5 13.9 21.9 18.8 16.4 19.0 19.8 11.1 13.3 9.3 16.6 17.9 21.1 22.4 15.3 8.8 35.0 23.2 18.9 27.4 16.1 12.2 21.9 15.7 18.4 19.4 33.8 9.4 20.7 18.3 18.1 11.9 18.2 17.4 16.2 14.5 18.4 20.5 11.9 18.8 20.0 28.9 18.6 17.0 20.0 19.2 13.9 30.3 17.4 9.5 11.5 6.9 5.7 18.1 17.0 3.1 16.1 19.7 13.5 15.7 6.1 9.5 14.0 0.1 13.7 11.4 9.1 9.9 13.8 14.2 0.7 11.4 6.1 9.6 25.6 16.4 16.3 18.1 21.2 10.5 26.6 11.8 16.6 21.6 11.2 11.9 12.1 14.8 5.2 9.9 6.9 9.8 15.9 14.9 12.4 8.1 5.7 12.3 18.9 19.2 8.7 9.5 14.3 15.0 13.4 28.6 15.5 18.2 19.9 11.3 9.8 18.5 19.8 20.0 19.2 15.3 20.6 19.2 23.8 18.6 21.6 23.5 17.0 18.6 30.3 22.2 8.2 13.9 16.6 12.7 21.5 17.4 13.5 15.9 20.1 15.5 13.3 9.3 15.3 8.8 12.2 14.5 TRIM41 "MGC1127, RINCK" ENSG00000146063 "Tripartite motif containing 41" Q8WV44 5 181222499-181235809 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.7" "Cell line enhanced" "Detected in all" "HDLM-2: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024204 Approved Supported "Nucleoli,Nuclear bodies" "Nucleoli, Nuclear bodies" "HPA024204: AB_1858299" "unprognostic (1.13e-1)" "unprognostic (7.05e-2)" "unprognostic (1.23e-2)" "unprognostic (7.93e-2)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (9.56e-2)" "unprognostic (7.24e-2)" "unprognostic (8.66e-2)" "unprognostic (6.87e-2)" "unprognostic (2.21e-3)" "unprognostic (2.07e-1)" "unprognostic (5.17e-3)" "unprognostic (2.45e-3)" "unprognostic (1.34e-1)" "prognostic unfavourable (4.22e-4)" "unprognostic (2.68e-2)" 10.0 8.3 25.5 9.4 24.3 9.3 5.4 7.3 17.0 6.9 6.5 19.8 8.8 11.2 6.1 8.3 7.3 8.4 7.0 9.8 26.9 20.4 10.7 7.6 6.9 6.0 37.3 12.5 5.9 12.3 18.8 7.6 7.3 17.0 7.0 4.0 7.8 8.3 8.4 30.0 9.0 9.0 5.3 43.7 7.5 9.5 19.1 18.3 10.6 11.3 7.2 7.2 5.8 5.2 2.2 2.4 3.9 2.3 1.9 4.3 1.4 4.6 12.1 4.5 7.5 5.4 5.4 10.6 6.8 3.7 5.0 4.7 10.2 7.0 7.8 11.1 4.6 8.8 4.7 16.3 2.7 38.5 14.9 8.9 11.9 5.8 5.2 6.5 6.1 4.7 8.4 6.2 2.2 2.8 11.1 9.7 2.8 16.6 9.8 7.3 4.2 5.8 9.3 6.9 10.2 2.9 7.4 7.0 6.6 6.3 7.4 9.5 14.8 7.4 5.9 6.9 4.7 4.1 5.1 21.4 13.5 11.1 7.2 7.7 5.8 0.9 1.4 2.2 2.4 1.1 3.6 1.9 2.5 4.3 1.6 2.2 2.6 3.1 3.9 1.9 2.3 2.4 3.2 1.4 25.5 24.3 7.3 17.0 26.9 20.4 37.3 12.5 17.0 18.3 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663557-5938619 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 12.5 15.0 3.7 11.6 6.7 3.0 10.7 2.4 5.1 14.2 8.5 4.8 20.1 8.4 16.1 19.9 12.0 11.9 9.9 7.8 5.6 2.9 15.1 16.2 15.2 9.2 6.5 2.9 15.3 24.8 6.1 9.2 12.2 8.8 11.8 8.3 11.8 22.0 12.4 3.0 6.5 13.2 12.0 9.0 19.8 9.5 7.7 6.5 24.9 20.5 7.9 13.3 14.8 12.3 3.9 11.7 13.8 9.8 5.9 5.4 4.6 4.6 7.2 12.3 8.6 13.7 12.6 3.6 9.9 18.6 20.3 27.5 7.3 9.3 3.0 7.8 9.7 7.6 10.0 14.5 9.2 6.4 2.7 9.0 5.0 5.8 12.2 6.6 9.7 9.5 13.0 6.7 17.8 31.3 9.4 6.1 17.0 2.1 5.4 3.0 5.6 5.1 8.4 2.6 0.8 14.1 8.9 0.3 0.7 7.0 10.1 4.4 5.2 3.8 23.6 9.6 12.7 1.8 2.4 5.5 3.8 1.2 8.9 4.4 9.8 10.2 9.8 12.9 5.4 9.8 5.3 3.9 4.1 4.3 11.7 3.9 3.4 4.9 13.8 5.9 9.2 9.7 3.3 4.6 3.7 6.7 2.4 5.1 5.6 2.9 6.5 2.9 8.8 6.5 TRIM50 "FLJ32804, TRIM50A" ENSG00000146755 "Tripartite motif containing 50" Q86XT4 7 73312539-73328082 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pancreas: 17.2;stomach 1: 22.8" "Cell line enriched" "Detected in single" 33 "Hep G2: 12.0" "Group enriched" "Detected in some" 8 "liver cancer: 2.9;renal cancer: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019862, HPA047843" Uncertain Approved Cytosol Cytosol "HPA019862: AB_1858305, HPA047843: " "unprognostic (1.93e-1)" "unprognostic (3.93e-1)" "unprognostic (1.07e-2)" "unprognostic (5.96e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.49e-1)" "unprognostic (3.04e-3)" "unprognostic (2.63e-2)" "unprognostic (2.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.33e-1)" "prognostic favourable (9.36e-7)" "unprognostic (3.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.25e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 17.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.0 0.0 0.1 22.8 4.4 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 12.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM56 RNF109 ENSG00000169871 "Tripartite motif containing 56" Q9BRZ2 7 101085439-101097967 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024358 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA024358: AB_1858308" "unprognostic (6.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.99e-2)" "unprognostic (1.62e-1)" "unprognostic (9.44e-3)" "unprognostic (8.30e-2)" "prognostic unfavourable (3.87e-4)" "unprognostic (2.63e-1)" "unprognostic (4.11e-1)" "unprognostic (3.90e-1)" "unprognostic (1.91e-1)" "unprognostic (1.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.47e-3)" "unprognostic (8.13e-2)" "unprognostic (1.49e-1)" "prognostic favourable (2.13e-4)" 14.3 12.0 6.2 15.7 9.3 4.7 24.5 3.2 11.1 14.9 15.0 6.8 22.3 9.7 14.3 13.1 12.9 12.8 13.7 8.7 7.5 5.2 10.8 10.4 23.7 11.7 15.8 5.2 17.3 10.8 10.7 15.2 14.0 8.8 12.5 8.3 7.5 12.2 22.1 8.7 13.2 12.8 15.2 8.5 17.2 10.3 5.6 12.0 9.7 14.0 9.1 12.0 13.6 22.0 3.3 2.1 7.4 2.4 7.7 3.6 1.0 9.9 12.5 5.4 6.9 12.5 13.0 6.5 8.3 7.4 13.5 12.6 5.9 14.5 11.8 9.0 6.9 11.5 2.2 7.6 9.1 11.8 3.5 7.4 15.7 4.4 11.2 13.1 16.9 8.2 11.1 8.8 14.4 7.1 12.9 15.0 9.3 13.6 11.0 14.6 5.4 10.4 10.2 8.8 7.7 7.1 10.4 0.3 0.2 9.2 25.8 7.0 5.9 8.6 13.4 19.0 16.9 14.2 8.9 7.4 7.4 9.3 9.4 10.7 14.8 2.5 2.4 2.1 3.6 1.5 2.6 2.0 2.7 2.3 0.8 3.3 2.6 3.4 7.4 7.7 2.1 2.1 1.1 1.0 6.2 9.3 3.2 11.1 7.5 5.2 15.8 5.2 8.8 12.0 TRIM58 BIA2 ENSG00000162722 "Tripartite motif containing 58" Q8NG06 1 247857199-247878205 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;placenta: 22.4;thyroid gland: 15.2" "Cell line enhanced" "Detected in some" "HAP1: 7.9;HEL: 21.0;K-562: 11.6;PC-3: 20.2;U-2 OS: 16.5;WM-115: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023637 Uncertain 310000 "HPA023637: AB_1858309" "unprognostic (3.85e-1)" "unprognostic (5.24e-3)" "unprognostic (7.00e-2)" "unprognostic (6.52e-4)" "unprognostic (1.46e-1)" "unprognostic (3.47e-2)" "unprognostic (1.10e-1)" "unprognostic (4.14e-5)" "unprognostic (3.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (5.00e-2)" "unprognostic (3.31e-1)" "unprognostic (1.08e-2)" "unprognostic (3.34e-1)" "unprognostic (1.00e-2)" "unprognostic (2.57e-2)" 0.7 0.8 1.3 1.0 4.4 24.8 0.7 0.3 3.7 0.6 1.3 0.2 0.0 0.3 0.5 0.4 0.5 1.4 0.5 0.8 1.5 3.2 0.5 0.6 3.4 0.4 2.4 1.2 1.1 0.4 0.3 0.7 22.4 6.9 1.7 1.0 1.1 0.5 0.4 0.5 1.2 0.6 0.8 1.3 5.8 0.7 4.9 0.1 0.0 15.2 0.0 0.4 1.9 0.7 3.1 0.6 3.7 0.7 1.7 0.3 1.9 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 7.9 0.0 0.0 0.0 0.8 21.0 0.0 0.0 0.0 2.8 1.6 0.0 0.0 0.0 0.0 0.0 11.6 0.1 0.0 0.0 0.0 0.1 1.3 20.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.1 0.0 0.0 16.5 0.0 0.0 3.5 0.0 0.0 0.0 5.9 21.3 2.8 0.7 1.8 0.3 0.5 0.2 3.1 0.2 0.2 0.6 1.0 0.3 0.2 3.7 1.7 0.6 0.6 0.2 1.9 1.3 4.4 0.3 3.7 1.5 3.2 2.4 1.2 6.9 0.1 TRIM6 RNF89 ENSG00000121236 "Tripartite motif containing 6" Q9C030 11 5596109-5612958 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.7" "Cell line enhanced" "Detected in many" "BEWO: 13.6;NTERA-2: 16.2;TIME: 13.6;U-2 OS: 15.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "neutrophil: 3.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA060514 Uncertain "HPA060514: " "unprognostic (9.00e-2)" "unprognostic (2.10e-3)" "unprognostic (9.16e-3)" "unprognostic (1.82e-1)" "unprognostic (3.25e-3)" "unprognostic (3.25e-3)" "unprognostic (2.35e-2)" "unprognostic (3.26e-3)" "unprognostic (8.59e-2)" "unprognostic (3.40e-2)" "unprognostic (8.61e-2)" "unprognostic (3.90e-1)" "unprognostic (5.68e-2)" "unprognostic (4.65e-4)" "unprognostic (4.77e-1)" "unprognostic (3.33e-2)" "unprognostic (4.36e-1)" 3.7 5.8 0.6 1.5 1.3 1.3 3.0 0.2 1.4 4.2 2.6 1.4 3.2 0.1 4.2 4.3 6.0 3.1 1.8 2.6 0.8 0.7 42.7 1.1 2.2 0.2 0.7 0.6 3.9 1.8 1.9 1.9 10.9 2.1 3.9 1.2 6.6 14.7 3.9 1.3 1.1 2.2 4.7 1.4 2.8 1.6 15.5 1.0 1.6 3.8 1.1 3.2 4.9 3.7 0.3 2.2 3.9 0.7 1.0 0.3 0.4 0.5 11.7 0.8 0.0 1.4 2.2 13.6 3.1 2.3 3.1 3.1 0.3 2.5 0.0 1.8 3.1 2.1 5.3 4.8 4.5 0.3 3.6 1.4 1.2 0.0 0.5 4.6 6.4 3.8 4.6 4.4 3.1 2.7 5.5 0.2 1.3 0.2 0.0 0.6 16.2 4.1 5.4 0.0 0.1 0.7 4.7 0.0 0.1 0.0 6.1 0.6 2.3 0.8 13.6 3.0 15.9 0.0 3.3 0.1 0.1 0.0 2.7 0.0 2.5 0.7 0.7 1.4 0.3 0.0 0.1 0.3 0.1 0.0 2.2 0.2 0.1 0.1 3.9 1.0 0.0 0.9 0.1 0.4 0.6 1.3 0.2 1.4 0.8 0.7 0.7 0.6 2.1 1.0 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145402-33182059 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" "Vesicles, Focal adhesion sites" "HPA050061: " "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavourable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 4.8 11.8 10.1 6.4 19.2 9.3 6.2 19.0 13.9 5.6 4.9 31.8 1.6 5.6 4.9 6.9 6.9 5.1 4.9 5.3 12.3 10.5 5.3 2.7 5.6 9.6 28.1 9.1 6.7 4.8 7.5 9.2 19.6 15.4 8.7 5.4 5.0 10.8 7.5 6.7 20.5 5.8 6.9 12.8 8.3 6.5 4.0 23.7 8.7 6.3 5.1 10.4 9.8 7.3 3.0 1.8 6.0 3.5 1.7 8.5 2.1 2.9 2.3 20.7 3.4 5.2 2.3 6.3 2.9 8.7 5.4 4.8 2.4 3.0 4.7 3.2 2.6 6.0 4.1 3.8 5.2 4.5 3.2 5.4 2.5 1.9 5.0 1.7 13.5 4.5 3.5 7.2 1.8 5.4 0.8 3.1 5.5 7.8 5.3 1.7 4.9 2.9 6.7 10.9 2.2 3.5 7.7 5.0 3.1 3.2 12.3 13.8 3.4 1.2 5.2 2.3 3.2 6.6 2.2 5.8 2.5 2.3 4.3 3.2 2.8 2.2 2.0 6.0 2.7 3.5 4.6 2.2 4.1 3.7 1.8 3.0 2.8 2.7 4.4 1.7 2.2 0.8 8.5 2.1 10.1 19.2 19.0 13.9 12.3 10.5 28.1 9.1 15.4 23.7 TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051304-26068436 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 271.4" "Group enriched" "Detected in some" 38 "ASC diff: 10.5;SK-MEL-30: 33.5" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" 3.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 1.2 1.7 0.0 0.6 38.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.5 0.0 3.6 1.0 0.0 271.4 0.6 0.1 0.9 0.1 0.0 0.1 0.1 0.0 0.0 1.7 12.7 0.8 1.2 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TRIM68 "FLJ10369, RNF137, SS-56" ENSG00000167333 "Tripartite motif containing 68" Q6AZZ1 11 4598672-4608259 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023455 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA023455: AB_1858319" "unprognostic (4.77e-2)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (4.10e-2)" "unprognostic (4.13e-2)" "unprognostic (8.63e-2)" "unprognostic (2.01e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-1)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "unprognostic (7.78e-2)" "prognostic favourable (4.14e-6)" "unprognostic (4.23e-2)" "unprognostic (2.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" 7.7 11.3 11.1 8.0 11.1 3.1 10.6 15.2 12.8 16.3 10.9 12.6 18.2 10.3 10.6 12.2 8.0 12.6 10.3 9.4 9.6 7.9 14.9 12.7 11.7 7.6 13.1 10.5 17.3 9.9 12.6 10.5 9.8 10.0 16.8 10.1 9.9 12.0 17.5 8.7 7.6 9.8 9.8 11.9 10.7 12.4 13.2 9.5 10.0 17.8 6.7 8.9 11.7 8.4 9.1 5.9 8.9 5.2 5.5 12.8 7.6 8.3 9.3 3.9 6.3 6.3 10.3 0.0 9.2 6.7 8.3 7.6 1.2 8.6 5.7 5.6 4.6 9.8 3.8 6.4 7.2 14.1 7.4 6.9 2.4 0.0 7.3 11.1 9.8 7.9 9.4 4.9 7.4 10.5 6.4 3.0 7.4 2.0 9.1 3.0 4.5 7.7 7.3 5.5 0.2 5.4 3.7 2.0 3.7 0.0 9.3 5.8 4.0 5.6 8.4 11.2 7.7 11.2 4.0 11.7 12.6 8.3 7.7 4.9 10.5 6.4 2.7 8.9 9.0 5.1 10.1 9.1 9.9 10.0 5.9 7.9 12.8 10.1 0.3 5.5 5.2 4.0 8.7 7.6 11.1 11.1 15.2 12.8 9.6 7.9 13.1 10.5 10.0 9.5 TRIM69 "RNF36, Trif, TRIMLESS" ENSG00000185880 "Tripartite motif containing 69" Q86WT6 15 44728988-44767829 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 68.6" "Cell line enhanced" "Detected in some" "Karpas-707: 4.0;U-266/70: 13.5;U-266/84: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "T-reg: 8.2" "Lineage enriched" "Detected in many" 7 "T-cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA028894 Enhanced "HPA028894: AB_10603136" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" "unprognostic (4.10e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-2)" "unprognostic (4.20e-1)" "unprognostic (9.27e-2)" "unprognostic (4.95e-2)" "unprognostic (6.49e-2)" "unprognostic (3.53e-3)" "unprognostic (1.38e-1)" "unprognostic (3.72e-2)" "prognostic favourable (2.26e-5)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-2)" "unprognostic (1.49e-2)" 4.6 3.9 9.0 4.0 10.8 3.0 3.9 7.2 9.1 3.5 4.4 5.1 1.7 3.6 3.4 3.7 4.7 3.4 4.1 11.0 7.9 7.9 4.7 3.8 3.8 4.9 7.5 5.4 3.8 2.8 3.4 4.9 3.1 5.3 5.9 4.2 3.7 3.7 3.2 14.0 4.1 4.0 5.3 5.7 6.7 3.9 68.6 4.7 3.9 5.3 5.2 5.5 4.1 8.1 1.2 0.0 0.1 0.3 0.0 8.2 0.3 0.2 0.0 0.4 0.7 0.5 1.2 0.0 0.1 0.5 0.8 2.4 0.0 0.3 0.2 0.2 0.0 0.0 0.3 0.0 0.6 2.6 0.0 0.3 0.1 0.0 0.9 0.0 0.2 1.4 0.9 0.2 0.2 0.2 0.0 4.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.3 13.5 3.3 2.0 0.4 0.4 0.1 0.0 0.0 0.0 0.6 0.2 1.2 1.2 1.9 1.8 0.0 0.0 0.3 1.2 0.1 0.0 0.3 0.0 8.2 0.3 9.0 10.8 7.2 9.1 7.9 7.9 7.5 5.4 5.3 4.7 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 81.8;tongue: 34.0" "Cell line enhanced" "Detected in many" "HaCaT: 11.2;HDLM-2: 23.8;PC-3: 13.2;TIME: 10.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 16 "cerebellum: 21.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 4.9;T-cells: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 1.3 0.9 0.1 0.9 0.5 0.5 3.4 21.7 1.3 2.5 0.8 0.3 1.1 0.5 1.0 6.4 13.0 0.6 1.7 2.2 0.1 0.8 2.2 0.5 0.9 0.6 0.2 0.2 0.6 4.2 1.6 1.9 0.5 0.5 2.0 0.6 0.6 5.9 1.1 81.8 9.5 0.6 0.9 0.3 0.8 1.4 0.9 0.2 0.1 3.3 34.0 13.5 1.6 2.9 0.7 0.8 0.1 4.9 0.5 2.2 1.1 6.1 2.9 0.0 0.3 0.5 0.5 0.1 1.4 0.0 0.5 1.2 0.2 8.0 0.4 4.3 1.7 11.2 3.2 9.2 0.1 23.8 1.3 0.5 7.8 0.1 1.6 0.0 1.3 0.1 7.1 0.2 4.6 2.6 0.3 1.3 0.2 0.8 0.3 0.2 0.0 13.2 0.3 4.2 0.9 3.3 0.0 0.3 0.7 2.9 0.1 4.0 0.7 0.2 10.8 0.1 2.4 0.4 4.2 1.9 0.2 0.7 0.3 0.4 1.0 0.0 4.9 0.1 1.4 1.9 2.2 0.4 1.2 1.4 0.8 0.7 2.2 1.8 0.1 0.5 1.4 0.6 2.2 1.1 0.1 0.5 21.7 1.3 0.1 0.8 0.2 0.2 0.5 0.2 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32818018-32897826 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 6.5;testis: 11.1" "Cell line enhanced" "Detected in some" "AF22: 12.4;BEWO: 37.5;CACO-2: 8.8;Hep G2: 24.2;NTERA-2: 33.2" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: , HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.1 0.0 0.7 0.1 1.9 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.7 2.2 0.0 6.5 0.0 0.2 0.0 0.1 0.0 0.0 0.5 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.1 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 37.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.6 0.0 24.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.2 2.6 33.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.5 2.7 0.7 0.2 0.0 1.9 0.0 TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102642310-102660680 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA023560: AB_10600414, HPA023561: AB_10601861" "unprognostic (4.32e-2)" "unprognostic (6.90e-2)" "unprognostic (3.02e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-1)" "unprognostic (5.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-3)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.34e-2)" "unprognostic (1.36e-2)" 31.7 18.4 26.1 23.9 25.2 17.0 18.0 26.1 31.6 31.8 19.5 22.9 15.4 15.8 18.0 14.3 17.8 21.6 19.8 25.0 23.2 18.0 27.2 21.9 23.0 25.4 20.1 20.0 19.3 35.9 24.7 14.7 17.5 16.3 17.4 8.1 19.4 28.5 18.5 34.8 14.6 23.7 13.6 15.7 22.5 21.2 11.7 21.9 48.3 26.6 14.5 30.3 21.4 15.9 9.0 11.9 17.8 5.3 5.5 7.2 3.9 27.6 6.5 6.4 10.5 7.1 14.4 6.0 9.9 20.2 10.8 8.7 11.7 33.4 8.9 26.7 22.0 10.2 4.3 13.3 8.9 9.0 8.4 22.5 5.4 26.7 18.1 5.0 9.0 16.5 7.4 23.7 14.0 14.3 4.2 13.4 8.4 18.0 9.5 16.9 3.5 13.2 4.8 14.4 4.4 12.8 19.5 3.9 7.6 5.5 6.8 13.1 19.2 10.0 26.6 14.5 6.5 8.1 22.2 12.3 8.0 5.2 22.1 12.6 3.6 10.7 4.8 2.6 6.8 4.4 6.7 9.0 7.2 5.3 4.1 7.0 6.4 5.5 17.8 5.5 5.3 11.9 6.9 3.9 26.1 25.2 26.1 31.6 23.2 18.0 20.1 20.0 16.3 21.9 TRIM9 "RNF91, SPRING" ENSG00000100505 "Tripartite motif containing 9" Q9C026 14 50975262-51096061 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 61.5" "Cell line enhanced" "Detected in some" "AN3-CA: 19.3;HAP1: 13.7;HDLM-2: 21.0;SCLC-21H: 19.9" "Cancer enriched" "Detected in some" 8 "glioma: 25.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.22e-1)" "unprognostic (6.37e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-3)" "unprognostic (6.67e-2)" "unprognostic (1.13e-2)" "unprognostic (2.24e-3)" "unprognostic (7.66e-2)" "unprognostic (1.88e-1)" "unprognostic (3.06e-2)" "unprognostic (2.38e-3)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (9.00e-2)" "unprognostic (7.57e-6)" "unprognostic (1.85e-3)" 1.9 3.9 21.5 2.7 20.9 2.2 2.7 49.1 61.5 2.1 2.5 10.3 0.0 1.5 4.8 3.0 1.7 1.5 6.5 1.7 17.4 11.4 1.9 3.6 1.5 1.5 10.8 21.7 2.3 1.9 1.5 5.7 1.6 13.0 2.0 2.4 1.8 3.9 5.2 1.5 1.6 1.7 5.2 7.1 1.6 1.7 2.0 11.5 0.0 1.5 0.0 1.5 2.0 0.9 0.0 0.1 0.8 0.0 0.0 0.4 0.4 0.0 2.2 3.4 19.3 0.0 0.0 1.3 0.0 0.0 0.2 0.5 1.5 0.1 0.2 0.1 0.3 0.0 13.7 0.0 0.5 21.0 2.8 1.0 0.0 0.0 0.0 0.7 0.7 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.5 0.0 4.1 0.5 1.1 2.9 2.4 5.0 0.1 0.0 0.0 19.9 1.5 0.3 0.0 4.2 0.3 0.5 0.0 1.3 0.5 0.0 0.9 0.3 0.0 0.2 5.8 0.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.4 21.5 20.9 49.1 28.6 17.4 11.4 10.8 21.7 13.0 11.5 TRIML1 "FLJ36180, RNF209" ENSG00000184108 "Tripartite motif family like 1" Q8N9V2 4 188139419-188147743 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 14.1" "Cell line enriched" "Detected in single" 9 "BEWO: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (6.99e-2)" "unprognostic (5.21e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIML2 "FLJ25801, SPRYD6" ENSG00000179046 "Tripartite motif family like 2" Q8N7C3 4 188091273-188109603 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 9.8;testis: 6.2" "Cell line enhanced" "Detected in some" "A549: 21.1;BEWO: 11.7;hTCEpi: 13.7;NTERA-2: 21.7" "Cancer enriched" "Detected in some" 33 "testis cancer: 24.4" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043838 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA043838: AB_10963835" "unprognostic (3.32e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (9.82e-2)" "unprognostic (1.21e-5)" "unprognostic (3.06e-2)" "unprognostic (1.65e-3)" "unprognostic (2.65e-1)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" 0.1 0.1 0.2 0.1 1.4 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 9.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 6.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 21.1 0.0 0.0 0.0 0.1 11.7 0.1 0.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 4.0 0.1 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: " "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavourable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.2 4.4 10.6 5.0 22.7 29.8 12.1 11.3 13.5 9.1 10.5 2.8 4.8 2.8 8.5 15.4 3.7 1.7 5.3 18.9 7.8 2.5 1.5 11.8 3.5 11.8 3.7 4.2 13.9 5.6 32.2 10.3 8.0 0.3 1.9 22.0 2.3 0.0 2.6 2.6 4.0 2.8 6.4 9.4 8.9 5.5 4.8 19.5 9.6 2.5 5.0 1.5 0.5 18.6 17.6 11.2 12.7 13.3 0.0 0.6 3.6 62.5 2.4 4.1 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 TRIP12 KIAA0045 ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763838-229923239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" "Nuclear speckles" "HPA036835: , HPA045893: " "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavourable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 29.6 28.1 23.6 25.4 26.9 26.9 23.1 20.5 26.2 24.0 23.1 26.2 24.3 14.3 25.3 26.3 30.6 19.9 20.7 35.9 19.0 19.3 26.2 24.9 26.2 26.5 23.1 20.5 24.3 18.8 32.4 33.1 27.2 24.8 25.8 21.3 22.3 25.5 22.0 62.7 23.6 22.0 26.2 23.3 32.5 23.4 77.1 24.0 42.2 28.0 21.5 31.5 26.5 27.4 7.0 9.1 25.8 12.0 9.1 12.7 6.1 23.8 26.9 24.7 20.7 23.6 28.7 23.0 36.8 25.0 26.7 29.8 21.5 19.2 9.3 27.0 32.8 18.7 36.0 26.2 39.2 38.2 13.1 64.8 22.6 19.0 20.4 48.7 42.4 24.8 20.2 44.4 28.5 34.8 47.8 10.0 30.5 18.1 27.2 16.8 19.3 12.3 24.8 48.8 8.2 19.8 41.0 25.1 17.9 0.5 12.4 25.3 12.5 29.8 48.3 34.6 24.6 22.5 28.4 17.4 19.9 30.5 26.4 19.2 29.0 18.8 9.9 15.7 9.5 11.3 9.7 7.0 8.8 9.2 9.1 6.8 7.3 7.0 25.8 9.1 12.0 9.0 12.7 6.1 23.6 26.9 20.5 26.2 19.0 19.3 23.1 20.5 24.8 24.0 TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39841022-39883511 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024174 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA024174: AB_1858346" "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavourable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavourable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavourable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" 9.5 10.3 12.9 10.4 19.1 8.0 19.8 25.8 18.4 15.1 13.4 15.9 22.7 11.4 19.3 21.3 19.8 18.4 9.1 15.9 12.5 12.0 14.6 13.2 11.9 14.8 13.9 10.4 16.7 27.7 14.1 26.7 17.6 14.4 21.4 15.8 13.5 15.1 23.9 10.1 22.9 11.7 18.0 9.8 14.0 12.9 17.3 17.9 15.4 19.2 9.4 14.7 17.2 17.5 3.9 13.4 0.9 6.6 2.4 5.2 2.8 14.5 6.7 14.6 14.9 7.3 11.0 22.0 9.7 13.0 15.6 17.6 12.9 19.2 8.4 12.8 8.2 14.8 21.0 16.7 21.9 10.3 10.6 18.0 15.6 8.0 16.9 17.5 9.9 9.3 15.1 19.5 19.3 12.5 24.4 10.2 9.7 7.1 13.3 18.8 19.6 6.1 14.2 18.3 19.3 14.8 18.7 16.6 11.1 13.9 9.5 10.6 10.5 30.0 8.9 10.4 12.8 18.0 16.0 13.8 10.8 17.1 13.2 17.9 9.0 0.0 6.6 0.9 2.7 4.9 5.2 3.9 2.6 2.9 13.4 3.2 3.4 3.5 0.1 2.4 5.8 11.6 2.7 2.8 12.9 19.1 25.8 18.4 12.5 12.0 13.9 10.4 14.4 17.9 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavourable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 15.5 15.0 19.1 19.8 23.5 23.1 16.6 19.5 22.6 15.0 16.3 17.3 15.5 14.9 19.2 19.0 17.6 19.6 19.4 13.2 15.7 13.4 14.4 17.3 13.5 26.8 22.1 14.7 29.1 23.8 16.3 14.4 14.4 21.9 18.1 14.5 10.9 14.9 15.6 21.4 22.1 16.1 16.5 12.4 25.0 16.3 16.8 20.1 12.2 15.6 12.1 19.6 17.3 18.8 11.2 14.9 3.1 15.7 4.3 10.2 8.5 15.3 10.4 11.3 19.1 11.5 14.7 16.2 17.3 8.7 19.1 16.6 11.1 12.7 19.3 22.7 9.3 14.3 18.8 15.2 8.9 12.6 26.3 15.3 26.7 18.6 20.8 30.7 18.1 20.8 20.5 19.9 18.7 14.0 33.2 6.2 11.8 17.0 12.4 33.2 26.7 24.4 21.0 14.5 26.6 11.9 15.7 26.8 12.2 10.8 22.5 18.0 8.7 17.2 15.6 27.6 10.7 16.6 30.3 10.7 20.7 17.8 12.9 32.5 14.3 1.2 15.7 0.5 8.1 11.9 7.7 10.4 8.6 7.7 14.9 11.2 10.2 7.7 3.1 4.3 7.5 8.8 5.6 8.5 19.1 23.5 19.5 22.6 15.7 13.4 22.1 14.7 21.9 20.1 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564032 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" "Nucleoli, Actin filaments" "Nucleoplasm, Cytosol" "HPA047601: , HPA058241: " "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavourable (2.14e-4)" "unprognostic (1.68e-2)" 7.0 8.9 6.5 7.5 8.9 3.3 13.1 6.1 8.7 4.6 6.0 9.3 7.5 7.3 5.5 7.2 9.2 10.1 6.1 5.0 7.9 6.7 9.1 16.8 4.9 7.4 9.2 6.1 6.6 12.4 6.7 12.2 10.0 9.7 7.4 6.9 2.5 7.3 4.7 9.3 6.5 10.4 5.1 10.5 7.0 7.6 16.7 10.1 10.7 10.8 5.1 8.0 7.2 10.8 8.8 10.0 9.2 7.6 5.8 7.1 4.0 6.6 4.7 9.2 4.7 5.5 7.7 6.7 8.1 3.1 5.7 4.3 3.9 8.3 9.2 3.1 4.8 3.9 10.7 5.1 8.8 11.7 4.7 6.3 4.1 6.4 5.2 16.0 6.8 4.9 13.2 5.7 12.5 5.8 14.6 8.3 4.8 7.7 13.5 3.3 5.5 4.6 7.8 8.8 5.9 7.7 5.5 5.8 5.0 4.4 24.6 8.1 8.0 6.9 4.2 5.8 6.0 4.7 9.2 5.8 9.7 8.4 4.4 9.4 4.1 4.0 7.6 3.7 3.8 7.1 3.1 6.3 6.5 6.4 10.0 8.8 6.7 6.2 9.2 5.8 6.2 5.6 7.1 4.0 6.5 8.9 6.1 8.7 7.9 6.7 9.2 6.1 9.7 10.1 TRMT10B "bA3J10.9, FLJ31455, RG9MTD3" ENSG00000165275 "TRNA methyltransferase 10B" Q6PF06 9 37753803-37778972 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021800 Uncertain Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA021800: AB_1856214" "unprognostic (1.00e-2)" "unprognostic (1.78e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (7.78e-2)" "prognostic favourable (3.91e-4)" "unprognostic (5.49e-3)" "unprognostic (1.71e-2)" "prognostic favourable (5.34e-4)" "unprognostic (1.40e-1)" "unprognostic (6.62e-2)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 7.4 10.3 9.9 10.9 10.3 10.1 9.8 13.7 12.3 10.6 11.8 12.7 12.8 8.3 17.3 9.5 10.4 9.6 10.6 7.0 9.9 9.2 8.2 8.0 8.6 13.1 16.4 9.8 15.4 10.5 9.0 13.8 7.4 10.0 14.8 7.1 12.1 10.3 12.1 7.8 20.4 9.7 11.8 12.7 12.1 10.8 5.0 10.4 10.0 12.4 5.6 13.6 14.8 10.1 9.2 4.6 6.6 5.3 4.6 7.6 2.7 5.4 6.4 8.3 7.3 5.1 4.1 3.9 5.4 3.8 5.4 4.7 3.9 4.8 10.0 4.0 4.0 6.3 3.9 6.4 5.0 4.3 6.9 8.8 15.7 4.0 9.3 8.9 6.3 4.7 6.7 4.7 9.2 5.5 7.0 4.4 4.1 3.8 9.2 7.1 7.4 7.9 9.3 2.9 5.2 5.2 5.0 11.3 10.8 4.3 5.4 4.7 5.9 6.6 5.5 4.3 6.1 6.8 4.6 5.0 6.9 8.0 2.5 7.2 8.6 6.6 5.3 2.8 6.7 4.6 7.6 6.6 6.0 6.3 2.5 9.2 7.3 6.7 5.4 4.6 3.2 4.6 3.9 2.7 9.9 10.3 13.7 12.3 9.9 9.2 16.4 9.8 10.0 10.4 TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561862-101566446 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA036671: AB_10602085" "unprognostic (7.42e-2)" "unprognostic (2.68e-1)" "unprognostic (9.08e-3)" "unprognostic (4.47e-3)" "unprognostic (5.01e-2)" "unprognostic (5.55e-2)" "prognostic unfavourable (6.56e-5)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (5.42e-2)" "unprognostic (4.70e-2)" "unprognostic (3.28e-2)" "prognostic favourable (3.32e-5)" "unprognostic (2.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" 18.0 21.2 13.1 13.6 14.1 14.4 19.7 16.4 19.1 16.1 15.3 5.5 12.9 11.6 14.6 13.1 20.9 15.0 10.7 20.4 13.0 13.4 26.6 34.6 10.0 19.3 12.5 16.7 18.8 12.1 9.9 19.9 18.2 18.5 16.2 14.2 5.5 14.5 13.0 35.2 15.2 16.5 15.3 14.3 19.6 15.6 14.7 10.6 23.0 16.6 30.5 18.5 15.6 11.3 21.6 15.4 27.4 14.8 12.2 23.1 11.8 20.8 10.2 13.6 13.7 12.5 10.7 12.7 12.4 12.2 16.3 18.2 15.5 14.1 43.4 16.3 7.7 21.1 26.2 19.0 22.4 15.5 12.9 29.1 8.1 11.2 9.6 25.5 12.4 12.5 19.8 14.2 13.3 15.8 24.6 9.7 17.5 14.3 20.4 18.7 25.2 22.1 15.2 11.1 19.4 20.8 17.7 33.9 19.4 9.7 20.7 27.4 27.3 28.2 10.4 8.9 16.8 5.9 13.1 11.3 20.6 41.6 15.0 18.4 13.3 27.4 11.2 7.3 13.6 14.4 18.8 21.6 16.8 15.8 13.5 20.4 23.1 21.1 4.9 12.2 14.8 15.4 15.0 11.8 13.1 14.1 16.4 19.1 13.0 13.4 12.5 16.7 18.5 10.6 TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023939 Approved Approved Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA023939: AB_1848793" "unprognostic (2.54e-2)" "unprognostic (2.20e-1)" "unprognostic (7.81e-2)" "unprognostic (1.02e-2)" "unprognostic (8.75e-2)" "prognostic unfavourable (2.99e-5)" "prognostic unfavourable (5.10e-4)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.56e-2)" "unprognostic (4.72e-3)" "unprognostic (3.39e-2)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.25e-4)" "unprognostic (1.04e-2)" 10.8 11.6 16.7 8.4 20.9 4.1 15.0 13.8 18.3 11.8 9.5 8.0 6.8 7.5 11.9 10.7 9.6 13.2 8.6 9.9 19.4 9.9 12.9 9.8 9.8 11.8 13.6 14.3 8.8 10.1 14.7 17.7 8.9 14.7 12.0 11.2 7.8 12.0 11.0 18.0 9.9 9.6 14.3 12.9 11.0 10.6 11.7 13.4 9.1 14.9 12.0 10.7 10.2 8.5 5.8 5.0 6.3 6.1 5.1 7.6 4.4 7.4 6.5 5.4 4.2 10.3 5.3 1.3 4.7 5.5 7.0 6.0 3.9 5.2 7.6 6.5 4.8 5.2 7.7 7.7 8.3 7.5 5.8 7.3 6.2 1.3 8.1 0.0 5.9 6.5 10.4 6.8 8.7 5.8 10.2 5.3 4.3 37.1 8.5 3.1 0.0 6.0 2.7 3.6 5.0 6.4 8.1 9.2 7.3 6.9 26.1 9.7 7.4 3.1 4.6 4.8 12.7 3.6 5.3 5.5 7.7 2.9 4.4 2.6 3.9 0.5 6.1 6.3 4.5 4.9 5.6 4.0 6.1 4.6 5.0 5.8 7.6 7.4 2.4 5.1 5.5 1.5 3.7 4.4 16.7 20.9 13.8 18.3 19.4 9.9 13.6 14.3 14.7 13.4 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150497 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavourable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavourable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 13.0 12.2 13.9 21.7 24.1 5.9 18.3 26.5 22.5 17.4 13.1 18.2 24.2 13.6 17.4 15.4 13.7 13.9 9.6 12.0 14.4 9.0 12.1 13.0 9.6 20.9 23.1 12.8 21.4 18.1 23.8 26.8 13.2 15.6 14.9 14.4 10.8 14.3 17.4 16.9 17.9 14.2 14.3 19.4 16.5 12.6 11.1 25.8 17.8 16.5 12.0 17.6 13.9 15.8 15.1 9.6 2.2 4.5 5.4 13.6 3.9 10.6 6.2 10.5 7.3 5.7 11.2 11.5 11.3 4.5 8.6 7.2 7.4 4.4 17.6 14.1 9.0 9.7 19.3 8.7 15.0 17.7 15.3 10.5 13.8 7.1 10.3 18.1 9.9 7.8 10.0 16.3 21.5 7.8 22.0 11.4 8.6 4.0 14.8 9.6 14.6 12.6 15.9 15.9 9.6 7.1 8.5 6.9 11.5 10.4 10.0 13.3 5.9 16.1 8.1 11.5 7.7 9.6 15.0 14.6 11.8 20.9 13.0 14.6 4.4 0.1 4.5 2.2 8.5 4.4 10.4 14.8 9.0 8.3 5.2 15.1 13.6 11.1 1.9 5.4 3.5 9.6 6.2 3.9 13.9 24.1 26.5 22.5 14.4 9.0 23.1 12.8 15.6 25.8 TRMT2B "CXorf34, FLJ12687" ENSG00000188917 "TRNA methyltransferase 2 homolog B" Q96GJ1 X 101009346-101052116 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003745, HPA035120, HPA040814" Uncertain Approved "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA003745: , HPA035120: AB_10601702, HPA040814: " "prognostic unfavourable (1.58e-5)" "unprognostic (6.72e-3)" "unprognostic (3.28e-1)" "unprognostic (1.54e-2)" "unprognostic (4.44e-1)" "unprognostic (8.74e-2)" "unprognostic (3.52e-2)" "unprognostic (8.16e-3)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (8.80e-2)" "unprognostic (2.78e-2)" "prognostic favourable (2.30e-7)" "unprognostic (4.58e-2)" "unprognostic (4.82e-1)" "unprognostic (5.03e-2)" "unprognostic (1.60e-2)" 7.6 10.4 6.9 8.9 10.3 9.1 8.5 7.0 14.2 9.6 11.4 6.9 10.7 8.1 8.1 8.6 12.9 7.4 7.3 13.0 10.7 6.6 12.3 9.5 9.4 12.6 9.5 6.6 11.3 10.4 18.5 17.6 5.9 10.7 10.1 12.6 13.4 15.3 10.4 17.6 9.5 13.5 7.9 8.4 16.6 11.4 4.0 7.9 18.2 12.8 5.3 17.7 9.9 9.5 16.5 8.1 14.8 8.2 14.4 19.2 11.5 15.6 13.6 2.8 6.4 6.4 3.4 8.6 8.1 11.0 9.2 13.7 14.6 12.5 13.9 16.3 7.5 9.8 12.5 11.3 11.5 12.0 7.9 8.8 11.2 6.9 5.7 15.6 14.4 4.3 6.7 13.2 6.1 17.6 9.0 13.3 8.4 15.8 19.4 8.3 3.8 10.1 15.9 13.4 13.3 6.7 9.3 4.1 5.4 13.9 10.1 8.1 6.6 7.5 10.3 11.6 7.0 10.8 7.2 8.5 12.7 13.0 9.0 18.0 8.9 9.6 8.2 14.8 13.8 6.5 14.6 14.9 16.1 13.3 7.4 16.5 19.2 16.1 4.8 14.4 7.0 8.1 13.0 11.5 6.9 10.3 7.0 14.2 10.7 6.6 9.5 6.6 10.7 7.9 TRMT44 "C4orf23, FLJ35725, METTL19, TRM44" ENSG00000155275 "TRNA methyltransferase 44 homolog" Q8IYL2 4 8436140-8493531 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045461 Uncertain Approved Nucleoplasm Nucleoplasm "HPA045461: AB_10961276" "unprognostic (1.50e-1)" "unprognostic (1.65e-3)" "unprognostic (3.47e-1)" "unprognostic (1.01e-2)" "unprognostic (2.06e-1)" "unprognostic (1.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.78e-2)" "unprognostic (3.46e-1)" "unprognostic (8.13e-2)" "unprognostic (3.44e-3)" "unprognostic (2.69e-3)" "unprognostic (1.49e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (6.76e-2)" "unprognostic (8.34e-3)" 11.5 7.6 13.3 7.3 17.5 13.1 15.4 20.3 16.2 10.1 9.2 14.1 10.1 7.1 16.3 10.7 13.6 12.3 8.6 9.8 12.1 6.3 7.1 8.9 8.8 9.8 12.2 14.7 17.1 9.7 11.3 10.9 10.2 8.7 10.8 7.2 9.4 12.4 8.7 11.5 17.2 7.6 9.7 6.7 8.1 11.3 15.8 13.8 7.8 9.9 9.0 10.7 10.8 11.4 2.1 2.1 0.4 2.1 0.8 3.0 0.5 5.5 5.8 7.3 8.6 7.8 7.6 15.9 6.6 4.7 8.8 7.9 7.1 7.9 7.6 3.2 2.6 4.3 10.6 6.5 7.7 3.8 5.2 7.1 9.1 5.6 6.7 12.2 5.9 4.6 8.9 6.7 7.3 9.3 10.8 8.2 5.5 3.6 10.1 8.9 8.3 8.8 7.5 7.8 4.8 7.5 6.7 8.0 5.5 4.3 3.9 5.8 3.5 4.7 5.5 5.4 3.0 5.0 10.1 9.6 6.0 7.0 5.9 11.4 5.2 0.4 1.2 0.1 2.3 1.2 1.6 0.8 2.1 2.5 2.1 2.1 3.0 0.9 0.2 0.8 2.1 1.7 0.2 0.5 13.3 17.5 20.3 16.2 12.1 6.3 12.2 14.7 8.7 13.8 TRMT5 "KIAA1393, TRM5" ENSG00000126814 "TRNA methyltransferase 5" Q32P41 14 60971451-60981358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000943 Supported Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA000943: AB_1080388" "unprognostic (1.58e-2)" "unprognostic (3.62e-2)" "unprognostic (6.63e-3)" "unprognostic (1.11e-2)" "unprognostic (7.70e-3)" "unprognostic (2.26e-2)" "unprognostic (7.82e-3)" "unprognostic (4.50e-2)" "unprognostic (3.95e-1)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (2.84e-2)" "unprognostic (1.60e-3)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" 15.8 10.1 7.9 13.8 12.1 5.4 12.9 9.3 11.8 10.9 8.6 5.7 11.9 7.5 12.0 10.9 11.1 10.0 6.7 6.8 7.7 7.1 12.5 13.9 6.6 7.3 6.7 8.3 17.1 11.1 15.9 13.1 10.8 9.0 10.6 8.1 4.8 11.5 9.9 14.8 9.7 7.4 9.2 6.3 8.6 8.1 24.9 5.9 12.4 10.4 12.1 7.2 13.3 9.0 7.2 7.4 0.9 7.5 2.0 6.0 3.7 28.3 7.3 10.7 14.9 9.4 14.2 11.7 10.7 8.2 11.5 9.1 5.3 17.0 14.6 11.9 7.7 13.1 13.4 15.4 15.1 14.4 6.8 10.7 4.9 5.9 15.4 18.9 6.0 11.2 15.0 10.4 15.4 10.0 13.9 5.2 16.8 10.7 9.7 9.5 9.8 12.0 3.1 24.8 12.3 9.7 9.6 13.1 13.0 11.9 11.9 9.4 19.9 11.4 9.4 13.3 16.1 9.4 10.1 3.2 6.0 6.9 9.3 4.1 12.4 0.1 4.6 0.9 3.5 7.5 5.0 7.2 5.2 5.2 4.2 4.9 5.6 5.1 0.4 2.0 7.5 7.4 6.0 3.7 7.9 12.1 9.3 11.8 7.7 7.1 6.7 8.3 9.0 5.9 TRMT61A "C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61" ENSG00000166166 "TRNA methyltransferase 61A" Q96FX7 14 103529184-103537073 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.12e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (5.59e-3)" "unprognostic (1.49e-1)" "unprognostic (3.70e-2)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (3.70e-2)" "unprognostic (9.86e-3)" "unprognostic (2.88e-3)" "unprognostic (4.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (1.28e-1)" 12.4 10.6 9.0 10.4 16.4 9.1 8.2 10.3 16.7 9.7 16.7 16.0 9.2 10.5 14.9 8.9 10.6 14.3 10.9 6.2 10.7 8.1 9.1 9.6 7.5 8.0 11.7 8.7 10.5 20.7 6.7 5.9 6.7 10.5 13.1 4.6 9.0 14.4 18.3 9.7 15.5 8.6 19.9 9.1 7.9 9.7 10.9 11.3 6.0 11.9 7.5 7.5 11.9 8.5 3.8 4.1 0.3 12.2 3.0 3.7 2.6 5.5 13.9 2.1 4.3 2.2 2.4 8.8 6.1 2.8 7.7 4.2 18.8 9.6 9.0 7.8 3.2 14.3 4.6 4.7 2.2 6.1 8.6 6.8 5.1 9.9 4.0 8.8 5.4 2.6 6.0 6.7 2.8 1.3 10.1 4.4 2.5 16.0 10.7 6.7 7.5 28.1 13.4 6.7 7.8 3.1 8.2 11.3 7.1 7.0 6.7 8.2 12.4 5.2 2.6 7.0 7.5 18.5 12.5 5.9 3.8 11.3 7.5 7.1 13.3 0.0 2.6 0.3 3.4 6.5 2.5 3.4 2.7 3.7 4.1 3.8 3.2 3.1 0.1 3.0 12.2 2.8 2.0 2.6 9.0 16.4 10.3 16.7 10.7 8.1 11.7 8.7 10.5 11.3 TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870301 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol Cytosol "HPA026747: AB_1848782, HPA026751: AB_1848784" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-3)" "unprognostic (2.05e-2)" "unprognostic (3.32e-2)" "unprognostic (4.14e-2)" "prognostic unfavourable (3.61e-4)" "unprognostic (2.36e-2)" "unprognostic (2.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-2)" "prognostic favourable (9.61e-5)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (5.38e-2)" "unprognostic (2.34e-1)" 11.6 19.5 20.4 12.8 22.5 10.9 18.5 33.7 21.0 13.8 11.7 17.4 10.9 19.2 15.6 20.4 12.6 11.8 10.1 16.3 17.2 18.4 19.8 16.9 9.0 13.8 17.0 15.6 13.7 10.0 21.1 25.4 12.2 17.8 15.2 13.2 14.2 12.6 11.8 17.9 11.9 18.6 14.4 14.7 13.2 12.4 14.6 18.7 12.6 12.8 10.4 14.5 14.8 10.8 11.9 6.8 2.7 7.0 13.9 12.4 6.3 17.8 10.8 10.9 19.3 15.0 12.9 13.2 10.6 13.2 13.6 12.8 12.3 9.7 19.0 9.8 9.3 14.0 15.2 12.9 14.1 14.2 10.3 5.8 8.9 16.1 17.0 12.2 6.6 13.1 14.5 10.8 14.8 13.0 11.7 7.3 11.2 7.1 10.7 18.5 20.3 17.3 8.0 17.7 16.3 11.9 11.6 18.6 19.7 11.5 18.2 17.5 9.3 4.3 10.1 9.1 15.3 8.9 13.3 9.1 14.9 29.4 12.1 18.4 12.2 0.0 6.6 2.7 9.8 7.0 12.1 11.9 11.1 10.5 6.4 11.6 12.4 8.9 0.9 13.9 5.7 6.8 11.6 6.3 20.4 22.5 33.7 21.0 17.2 18.4 17.0 15.6 17.8 18.7 TRMU "FLJ10140, MTO2, TRMT" ENSG00000100416 "TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA000824: , HPA035273: AB_10602901, HPA043300: " "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavourable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favourable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavourable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 8.5 16.1 11.5 9.9 16.0 6.4 7.5 17.8 16.0 9.7 8.7 11.5 10.2 10.9 12.1 18.0 10.9 6.2 7.3 16.8 11.3 11.9 20.5 18.8 7.1 10.2 15.7 11.8 8.0 22.7 20.0 13.6 9.7 11.2 8.7 10.2 9.0 12.5 15.5 17.8 9.8 7.6 9.4 11.4 8.7 9.2 8.3 13.9 6.5 9.6 8.3 9.8 7.1 9.1 6.2 7.6 3.9 9.6 7.5 11.3 6.3 10.8 9.9 4.3 9.6 8.0 5.7 10.7 11.3 8.0 16.1 12.5 14.0 2.7 7.1 8.0 10.1 9.7 18.1 10.1 13.8 4.6 24.4 8.4 15.2 16.5 6.9 16.1 5.8 5.4 11.4 16.6 5.3 10.3 11.7 1.7 9.7 11.4 6.2 13.2 16.1 17.5 7.4 9.2 13.1 8.0 7.5 10.2 12.3 10.0 11.8 18.9 6.7 6.7 7.5 7.2 12.8 10.1 12.6 4.2 4.5 7.6 10.1 11.7 14.4 0.0 6.8 3.9 11.1 9.4 9.4 5.7 9.4 10.0 7.6 6.2 8.6 8.0 1.4 7.5 9.6 6.0 11.3 6.3 11.5 16.0 17.8 16.0 11.3 11.9 15.7 11.8 11.2 13.9 TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126916-3150879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Mitochondria "HPA036938: AB_10670566" "unprognostic (6.39e-3)" "unprognostic (1.58e-1)" "unprognostic (2.38e-3)" "unprognostic (4.69e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (2.68e-1)" "unprognostic (6.22e-2)" "unprognostic (5.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-2)" "unprognostic (6.50e-2)" "unprognostic (1.09e-1)" "unprognostic (3.78e-1)" "unprognostic (1.02e-1)" 15.2 16.9 17.5 17.8 20.7 8.7 18.2 14.5 22.7 12.9 13.2 13.2 17.4 11.1 18.4 14.7 15.9 12.2 15.6 13.9 17.1 16.0 21.1 16.1 13.7 19.0 17.5 15.6 14.6 13.9 14.3 31.0 19.0 21.3 23.9 16.4 10.1 13.2 13.1 14.8 15.3 12.5 15.3 19.3 20.5 15.5 13.5 15.1 22.1 20.9 10.6 19.8 17.8 13.0 15.1 10.5 29.0 12.0 15.1 16.6 7.4 11.9 17.3 13.4 7.6 16.0 13.7 14.3 13.7 11.4 13.7 14.2 16.0 14.7 21.8 9.1 13.2 8.6 17.7 12.4 17.5 16.2 8.5 20.3 18.4 16.0 21.4 21.4 16.5 12.8 17.5 14.1 4.8 13.5 15.7 9.2 23.6 22.3 13.8 19.4 10.6 12.6 13.2 18.1 21.2 18.3 17.8 7.7 11.0 19.8 14.4 11.4 13.3 12.2 11.0 15.5 13.5 16.0 17.5 9.4 18.8 27.5 11.6 19.3 17.2 29.0 8.8 22.5 12.1 11.8 11.9 15.1 15.0 12.7 10.5 9.5 16.6 14.3 11.7 15.1 12.0 9.6 11.1 7.4 17.5 20.7 14.5 22.7 17.1 16.0 17.5 15.6 21.3 15.1 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.1;intestine: 19.5" "Cell line enhanced" "Detected in some" "BEWO: 7.5;HeLa: 4.4;Karpas-707: 2.5;RT4: 7.2;U-266/70: 2.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 16.1;neutrophil: 6.6" "Lineage enriched" "Detected in single" 30 "granulocytes: 16.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 2.9 0.0 1.3 0.5 1.2 2.5 1.1 1.3 1.2 0.8 13.3 0.2 1.0 7.2 0.4 0.2 0.6 0.4 1.0 0.5 1.9 1.2 3.1 0.2 1.5 0.2 2.6 0.0 0.4 0.2 3.8 4.9 0.2 1.6 1.7 17.5 0.4 1.1 0.0 1.6 0.8 19.5 0.7 5.0 3.9 0.2 1.7 0.5 1.6 0.3 1.1 2.1 0.5 0.6 0.3 0.3 16.1 0.1 0.5 0.1 0.0 0.0 1.6 0.2 0.2 0.0 0.0 7.5 0.1 0.0 0.0 0.1 2.1 0.2 0.6 0.0 0.1 0.3 0.5 0.5 0.0 0.1 0.2 0.2 4.4 0.3 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.2 0.0 2.5 0.1 0.9 0.0 0.1 0.6 0.2 0.0 0.0 0.3 0.0 7.2 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 1.1 0.2 0.0 2.7 0.0 0.2 0.1 0.1 0.3 16.1 0.1 1.9 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 6.6 0.5 0.1 0.3 0.0 0.0 1.3 1.2 1.3 1.2 1.9 1.2 2.6 0.0 1.6 0.5 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686815 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 91.8" "Cell line enhanced" "Detected in all" "U-2197: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: " "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 13.3 10.8 6.6 14.7 9.0 12.8 12.1 19.5 9.3 11.8 11.7 8.1 9.7 9.9 16.5 10.7 9.4 11.0 8.2 19.1 5.5 4.9 16.0 20.0 10.8 10.6 12.4 5.2 16.6 11.6 91.8 14.6 14.3 10.2 9.7 10.3 28.6 11.5 13.5 10.8 11.7 12.8 12.8 9.8 11.1 10.3 6.9 10.0 14.5 12.6 6.9 12.6 12.9 12.3 7.0 4.7 4.4 3.4 5.7 7.6 2.0 8.3 8.3 7.0 7.7 20.2 15.2 8.5 10.6 14.7 6.7 8.9 11.4 4.6 18.2 5.2 12.2 14.1 9.3 7.8 9.7 10.1 5.6 14.5 12.8 6.0 18.4 15.0 11.3 14.1 9.2 7.6 14.4 5.4 16.4 14.0 12.2 13.1 9.6 7.3 5.3 5.1 10.6 9.7 8.9 9.4 19.8 5.8 7.4 7.3 11.6 14.2 7.3 16.3 8.2 10.7 5.1 49.9 12.1 9.5 21.0 17.5 11.7 30.7 9.9 3.8 3.4 3.9 6.6 3.2 7.6 5.6 4.8 4.4 3.7 7.0 4.4 5.2 4.4 5.7 3.2 4.7 4.8 2.0 6.6 9.0 19.5 9.3 5.5 4.9 12.4 5.2 10.2 10.0 TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria Mitochondria "HPA038705: , HPA038706: AB_10671863" "unprognostic (2.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.84e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-3)" "unprognostic (1.12e-1)" "unprognostic (7.71e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (4.58e-3)" 8.1 12.2 10.8 11.1 12.6 4.4 9.1 6.4 12.1 8.8 15.1 10.9 37.4 12.5 7.8 15.3 13.3 10.4 13.5 34.4 10.9 10.3 16.9 13.7 7.0 8.3 13.6 8.5 8.7 23.3 9.1 11.6 8.5 10.8 11.3 10.8 9.9 22.3 33.5 58.8 10.8 13.1 7.0 10.1 10.3 12.2 18.9 10.3 17.2 13.3 23.9 13.2 11.9 7.7 22.9 31.7 14.5 16.2 12.4 13.2 6.5 10.7 10.7 11.9 19.1 14.8 10.8 14.7 7.2 14.1 12.9 10.9 7.0 16.4 10.9 29.3 11.9 15.1 5.2 15.7 4.5 10.5 6.4 5.5 10.8 12.1 21.4 6.9 9.8 8.1 9.2 14.3 12.7 9.0 9.6 12.1 10.7 25.5 12.8 14.8 7.6 11.9 16.9 8.9 30.7 33.1 12.9 10.5 15.3 5.8 14.3 21.1 16.6 11.2 10.5 8.9 6.8 17.2 7.1 24.4 6.0 6.9 21.3 3.6 14.2 6.0 9.4 14.5 10.9 16.2 8.4 20.8 10.5 11.2 13.0 22.9 11.9 13.2 8.3 12.4 13.9 31.7 13.2 6.5 10.8 12.6 6.4 12.1 10.9 10.3 13.6 8.5 10.8 10.3 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027827 Enhanced "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19130808-19132623 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "testis: 95.7" "Cell line enhanced" "Detected in some" "HL-60: 1.7;SCLC-21H: 3.4;THP-1: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.0 1.6 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 0.0 1.2 0.0 0.8 0.0 0.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.7 3.2 0.8 1.4 0.5 0.0 0.2 0.1 0.9 0.3 0.0 0.3 1.2 0.0 0.0 1.0 0.4 0.0 0.0 0.5 0.1 0.8 0.3 0.7 0.2 0.5 0.2 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.6 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 0.0 3.1 5.8 0.0 0.6 1.4 1.5 1.5 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" "Cell Junctions" "HPA060660: , HPA077103: " "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.0 3.9 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 3.8 0.0 0.1 0.0 1.6 3.0 3.4 4.8 3.0 0.0 1.5 3.7 0.0 0.0 0.0 0.6 0.1 1.3 2.0 0.0 3.8 3.6 1.6 0.7 3.2 2.9 1.5 2.6 0.0 5.2 2.2 2.0 2.7 2.5 0.8 1.6 1.7 1.4 2.9 1.8 3.7 1.3 4.2 4.8 4.7 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515685 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "testis: 50.8" "Cell line enhanced" "Detected in many" "BEWO: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.9 1.2 1.0 1.2 1.5 1.3 1.0 0.9 1.9 0.9 1.1 2.2 1.6 2.1 0.9 3.7 1.1 1.1 1.0 0.7 1.2 0.8 1.8 2.2 0.7 1.2 2.5 1.0 0.9 3.3 1.1 1.0 0.6 1.3 1.4 0.6 0.9 1.3 1.0 1.0 2.7 1.9 1.2 1.9 2.1 1.7 50.8 1.7 3.1 2.0 0.1 1.7 1.1 1.0 3.1 1.0 2.2 0.7 0.4 3.8 0.8 1.7 2.7 0.1 1.1 0.4 1.0 8.1 1.1 0.5 0.6 0.3 4.3 1.3 1.4 2.0 0.1 1.4 0.5 1.1 0.2 1.1 2.0 0.7 1.7 0.9 1.2 0.9 3.2 0.7 1.0 0.6 1.9 0.3 1.9 0.8 0.0 0.5 3.4 2.0 3.7 4.5 2.8 0.7 1.2 0.1 0.5 0.6 2.9 1.6 0.4 1.4 2.7 0.7 0.3 2.0 0.6 4.0 1.7 3.6 1.5 0.8 2.2 1.2 1.9 0.0 0.6 2.2 0.8 0.2 1.1 3.1 1.7 2.0 0.3 1.9 3.8 2.1 1.1 0.4 0.7 1.0 1.0 0.8 1.0 1.5 0.9 1.9 1.2 0.8 2.5 1.0 1.3 1.7 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 16.0" "Group enriched" "Detected in all" 6 "dendritic cells: 16.0;granulocytes: 14.3;monocytes: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria 2800000 Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favourable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favourable (1.04e-4)" 8.5 29.7 6.0 13.5 7.6 5.7 6.1 5.0 10.5 9.5 38.4 12.9 10.9 37.4 5.9 4.0 16.6 6.8 38.4 14.1 5.1 4.9 19.7 102.1 6.2 3.2 8.2 7.0 7.2 23.9 1.8 2.3 5.0 5.9 8.1 21.6 6.2 13.6 6.9 8.3 5.4 39.5 3.8 4.7 3.5 22.8 3.3 6.7 1.8 8.5 12.8 10.5 7.2 9.2 1.6 16.0 14.3 11.5 2.2 1.2 5.2 15.1 33.7 4.3 14.4 10.4 4.1 8.0 8.4 7.2 4.9 7.4 9.8 10.0 4.0 7.1 6.6 13.1 3.1 8.4 1.1 11.7 18.9 4.2 6.4 19.0 26.1 5.8 10.0 8.0 9.6 3.6 3.1 12.0 5.0 7.0 2.3 34.7 0.2 18.8 7.3 14.8 13.6 4.6 7.0 13.8 14.2 2.5 6.5 8.9 16.0 11.4 16.5 14.8 9.0 5.6 10.5 9.3 2.6 5.3 5.3 1.2 2.0 16.9 3.3 5.3 11.5 4.9 0.6 3.0 1.1 1.6 0.5 0.4 16.0 0.8 0.3 0.2 14.3 2.2 0.8 1.1 1.2 5.2 6.0 7.6 5.0 10.5 5.1 4.9 8.2 7.0 5.9 6.7 TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243680-43288259 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9" "Group enriched" "Detected in some" 9 "SCLC-21H: 20.8;SH-SY5Y: 7.9" "Cancer enhanced" "Detected in some" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA031735: , HPA031736: AB_10670294" "unprognostic (1.68e-1)" "unprognostic (7.88e-3)" "unprognostic (7.01e-2)" "unprognostic (1.62e-3)" "unprognostic (2.18e-1)" "unprognostic (2.24e-4)" "unprognostic (2.46e-3)" "unprognostic (3.01e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.01e-2)" "unprognostic (2.12e-4)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-3)" "unprognostic (3.04e-4)" 1.1 3.9 12.4 1.3 12.9 0.9 1.0 14.9 28.9 1.0 1.4 8.2 0.0 4.6 1.0 1.0 1.0 1.1 1.4 1.3 10.3 7.5 1.7 3.5 1.1 1.2 7.1 12.5 1.0 1.4 1.6 7.7 1.0 9.0 1.3 1.3 0.7 1.0 1.2 1.0 1.0 6.8 1.1 6.2 1.2 1.3 2.3 8.3 0.0 1.0 0.0 1.3 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 20.8 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 12.4 12.9 14.9 21.7 10.3 7.5 7.1 12.5 9.0 8.3 TTBK2 "KIAA0847, SCA11" ENSG00000128881 "Tau tubulin kinase 2" Q6IQ55 15 42738734-42920809 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018113, HPA049866" Approved Uncertain "Intermediate filaments" "Intermediate filaments" "HPA018113: AB_1858421, HPA049866: " "unprognostic (2.15e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (7.73e-2)" "unprognostic (4.26e-1)" "unprognostic (6.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.78e-2)" "unprognostic (8.62e-2)" "unprognostic (3.46e-2)" "unprognostic (7.29e-2)" "unprognostic (3.63e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" 6.7 7.3 8.7 5.1 14.0 8.0 6.0 17.8 22.0 7.0 7.2 10.9 3.8 3.3 8.5 6.2 4.2 7.8 6.2 10.7 9.4 11.5 6.1 4.3 6.1 5.5 11.1 14.8 11.5 3.3 9.0 13.9 8.8 24.7 8.2 5.6 7.6 4.8 6.5 11.6 6.3 4.6 8.4 10.9 7.1 4.9 41.8 10.8 3.6 6.7 1.9 5.4 6.8 8.7 2.5 1.4 1.3 3.0 2.1 3.1 0.7 6.1 3.4 9.2 4.9 6.3 6.6 1.9 5.1 7.2 4.4 6.6 4.6 1.4 4.0 6.4 4.8 4.1 8.1 6.0 6.7 12.9 5.7 4.9 7.6 1.9 4.9 7.0 8.6 5.2 6.2 3.9 20.8 5.5 7.4 6.5 4.1 0.8 4.7 5.0 2.6 3.8 7.9 8.7 1.9 5.5 3.8 6.9 7.8 12.4 0.9 2.6 3.2 8.7 6.7 5.7 5.7 7.0 7.0 7.5 10.0 5.9 4.2 5.5 3.6 0.4 3.0 1.2 1.7 1.4 3.1 1.5 1.6 1.3 0.8 2.5 2.1 1.5 1.3 2.1 1.5 1.4 0.5 0.7 8.7 14.0 17.8 22.0 9.4 11.5 11.1 14.8 24.7 10.8 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: " "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 22.9 22.1 34.0 18.7 36.5 12.0 23.4 39.2 40.0 34.9 20.6 15.9 26.7 13.0 21.6 33.3 15.3 19.5 19.0 21.5 29.1 16.5 21.4 17.0 15.4 14.3 17.7 27.5 34.5 25.8 27.4 50.4 15.2 34.7 28.9 19.9 16.1 24.5 25.4 21.6 16.1 16.8 21.6 21.7 13.6 21.3 19.5 19.9 19.7 35.4 11.1 15.1 23.3 18.9 10.6 12.8 4.8 5.7 9.1 18.6 3.8 21.4 7.6 35.7 6.7 34.5 50.2 12.4 23.6 29.4 10.7 14.5 10.1 10.8 18.5 8.2 39.5 7.0 10.7 14.5 15.1 19.6 7.7 37.4 11.5 13.1 12.6 20.8 12.1 25.9 9.0 10.8 9.7 15.8 22.5 21.8 20.0 16.6 20.2 5.4 10.1 13.0 27.1 17.1 9.7 12.4 16.6 27.3 20.8 29.3 16.8 15.2 19.0 8.2 20.5 15.3 6.1 18.7 8.8 21.9 15.7 18.5 25.2 20.9 11.5 2.9 4.4 4.8 9.1 4.8 13.6 9.5 10.6 12.3 7.9 10.6 18.6 11.3 0.7 9.1 5.7 12.8 7.2 3.8 34.0 36.5 39.2 40.0 29.1 16.5 17.7 27.5 34.7 19.9 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavourable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.7 1.1 3.5 13.6 15.5 9.6 22.7 27.8 10.9 10.2 19.8 12.1 6.6 17.4 21.2 9.5 31.7 18.0 17.1 18.3 10.7 8.9 0.0 21.5 12.0 0.4 1.0 15.9 10.2 12.8 20.0 20.5 19.3 9.9 12.3 15.6 14.2 9.7 11.0 43.9 8.2 5.7 8.6 16.6 9.7 9.1 9.9 5.6 9.3 16.4 5.3 10.2 10.2 6.6 24.8 4.6 15.5 11.0 3.6 20.1 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell line enhanced" "Detected in many" "RH-30: 4.8" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: " "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.7 0.0 0.0 0.0 2.3 2.0 3.7 2.6 1.0 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.4 2.1 1.2 0.4 0.4 1.6 2.5 0.4 1.8 1.3 4.8 1.3 0.0 0.6 1.0 1.7 0.4 1.3 0.0 0.7 2.4 1.6 0.0 0.0 0.9 0.4 3.5 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 TUT1 "FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase" ENSG00000149016 "Terminal uridylyl transferase 1, U6 snRNA-specific" Q9H6E5 11 62575045-62592177 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA069055, HPA071838" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA069055: , HPA071838: " "unprognostic (3.81e-2)" "unprognostic (3.54e-2)" "prognostic unfavourable (9.51e-4)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.59e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (2.71e-1)" "unprognostic (7.20e-3)" "unprognostic (1.03e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.97e-3)" 10.9 12.1 10.7 9.9 13.6 7.8 12.9 13.5 13.3 10.5 8.7 15.9 13.0 12.9 11.5 10.8 10.0 16.9 13.7 10.7 13.6 8.3 12.2 22.7 9.6 18.1 15.5 9.5 14.5 26.2 15.5 16.2 12.3 13.0 13.9 6.2 11.9 16.4 11.9 20.5 13.9 11.7 10.2 11.4 14.6 12.5 18.6 13.2 17.1 14.0 8.8 13.6 11.5 9.8 13.1 9.4 6.6 7.3 9.8 16.0 7.2 7.2 9.1 6.3 8.8 7.7 4.4 8.2 7.8 4.8 6.6 5.8 8.2 14.2 11.6 18.1 3.8 13.7 11.6 9.1 3.4 8.9 6.1 11.9 9.3 7.7 8.6 8.4 5.4 6.2 9.8 8.3 12.6 6.3 17.8 12.0 5.6 15.9 11.9 17.9 7.2 11.2 13.4 10.1 28.1 6.1 4.2 10.5 14.7 6.0 11.3 9.7 15.8 8.2 5.7 7.5 6.8 8.7 5.9 20.9 18.3 14.2 8.8 6.7 6.2 5.9 5.9 6.6 10.5 7.3 14.6 9.8 9.9 8.4 7.8 13.1 16.0 12.5 3.6 9.8 5.3 9.4 8.9 7.2 10.7 13.6 13.5 13.3 13.6 8.3 15.5 9.5 13.0 13.2 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134256 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 43.5;lymphoid tissue: 49.1;placenta: 28.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HMC-1: 11.0;U-266/70: 5.4;U-266/84: 6.7;WM-115: 24.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 43.5" "Group enriched" "Detected in many" 26 "NK-cells: 43.5;T-cells: 17.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles Vesicles "HPA062482: " "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 1.8 1.5 0.3 15.3 0.4 3.9 1.5 0.2 0.6 0.8 2.1 0.3 0.2 1.3 1.3 11.6 2.4 2.6 1.7 0.7 0.2 0.4 2.1 2.8 4.0 49.1 0.5 0.5 0.5 1.0 0.4 1.3 28.4 0.6 0.9 1.0 1.0 6.1 0.2 0.5 1.7 7.9 0.4 0.4 17.8 1.0 1.7 0.2 14.0 1.9 0.2 19.3 2.4 1.4 0.0 0.1 1.1 0.0 43.5 17.5 10.6 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 4.7 0.0 1.4 0.0 0.2 0.0 0.0 0.4 0.2 0.1 2.3 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.0 0.0 2.0 0.0 0.8 0.3 0.0 0.0 1.3 1.2 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.4 0.0 0.0 0.3 0.1 5.4 6.7 0.4 0.0 0.4 24.8 1.1 0.0 0.3 13.2 0.0 17.4 0.0 6.8 6.4 0.0 0.0 17.5 11.9 0.8 43.5 0.0 0.1 5.1 10.6 0.3 0.4 0.2 0.6 0.2 0.4 0.5 0.5 0.6 0.2 TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380676 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favourable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favourable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favourable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favourable (4.16e-4)" 16.8 19.0 22.9 36.0 22.6 49.4 17.5 24.4 23.9 17.8 19.4 26.7 13.9 20.0 19.3 20.2 15.0 16.8 21.8 17.0 18.3 14.0 24.0 34.4 27.5 31.5 24.7 17.4 20.0 21.3 19.0 24.8 13.9 19.1 21.1 18.6 21.6 24.4 15.4 15.6 24.4 23.8 16.7 17.9 47.9 18.5 6.4 22.8 33.9 20.9 13.5 34.7 16.7 15.1 5.8 15.8 22.9 13.4 5.3 9.1 7.3 8.5 12.5 7.5 11.7 10.0 14.1 7.2 11.7 12.0 14.9 16.4 9.6 5.7 13.0 13.8 13.1 8.6 9.0 13.8 7.9 22.9 14.0 24.0 24.9 23.5 15.6 10.1 27.7 13.6 9.8 16.9 10.0 14.4 10.1 36.4 13.1 26.9 14.8 62.3 2.4 21.9 14.8 6.4 13.3 12.1 27.6 7.0 8.7 11.5 12.1 8.4 6.7 17.2 12.2 20.1 7.2 23.1 13.7 30.0 23.3 11.9 10.0 21.1 11.2 6.6 13.4 17.0 9.1 10.2 5.9 5.6 5.5 8.1 15.8 5.8 3.8 5.1 22.9 5.3 9.7 9.0 6.8 7.3 22.9 22.6 24.4 23.9 18.3 14.0 24.7 17.4 19.1 22.8 TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530056 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 15.9;HHSteC: 39.3;Karpas-707: 38.0;U-266/70: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 23.0;eosinophil: 18.2;intermediate monocyte: 22.4;myeloid DC: 12.2;neutrophil: 6.7;non-classical monocyte: 15.9" "Group enriched" "Detected in many" 18 "dendritic cells: 12.2;granulocytes: 18.2;monocytes: 23.0" "Low region specificity" "Detected in some" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus" 16000000 "Nuclear bodies" "Golgi apparatus" "CAB002518: AB_563953, HPA000530: , HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favourable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavourable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" 25.2 7.9 2.8 41.6 8.4 12.1 19.0 1.5 4.4 10.7 10.7 3.8 2.3 10.4 4.4 15.7 22.0 13.7 9.6 15.0 7.0 2.6 18.6 38.1 28.8 57.8 6.5 0.4 7.5 5.8 1.7 3.9 11.5 9.1 7.9 4.9 5.4 16.5 3.8 10.0 8.8 13.9 7.3 15.2 43.9 12.4 3.0 5.0 13.3 12.5 25.5 28.8 12.4 9.4 0.9 12.2 18.2 23.0 0.8 0.9 2.6 6.5 0.7 0.0 0.1 0.9 1.2 0.6 1.1 0.1 2.4 5.3 0.0 15.9 0.5 0.8 2.7 5.8 0.2 0.2 0.0 2.8 1.4 0.3 1.1 0.4 39.3 0.1 7.6 2.4 2.4 3.2 0.0 0.0 0.2 38.0 0.2 0.1 0.0 1.0 0.0 2.1 0.2 0.0 7.6 0.0 0.0 0.0 1.4 6.1 8.3 0.5 0.6 4.8 1.5 0.0 0.6 0.1 0.2 18.2 3.7 0.4 0.2 0.1 0.2 2.5 23.0 18.2 0.3 22.4 0.2 0.8 0.3 0.2 12.2 0.9 0.2 0.1 6.7 0.8 15.9 1.1 0.9 2.6 2.8 8.4 1.5 4.4 7.0 2.6 6.5 0.4 9.1 5.0 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657604-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 75.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 13.8" "Group enriched" "Detected in many" 6 "NK-cells: 6.8;T-cells: 13.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "cerebellum: 6.7;olfactory region: 8.8" CAB002784 Enhanced "CAB002784: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 3.0 2.6 4.6 15.5 5.8 34.9 2.8 1.2 6.3 3.4 10.1 10.2 1.5 4.8 2.5 3.6 12.3 2.4 4.6 2.0 5.8 2.9 4.8 5.1 4.2 15.4 3.4 4.5 2.0 3.1 1.1 1.3 14.3 3.4 3.0 12.9 1.1 3.4 0.8 0.7 3.6 6.9 5.5 4.6 8.9 4.2 21.5 5.3 75.5 1.7 10.9 19.3 4.8 4.3 1.2 1.8 1.0 0.1 6.8 13.8 2.5 13.7 21.2 44.3 21.4 4.9 8.2 22.5 32.5 19.4 35.1 42.1 17.9 11.0 21.4 12.7 17.5 6.2 30.9 12.2 30.4 20.1 34.3 36.3 19.9 30.7 1.1 74.5 39.8 7.3 2.9 22.1 6.9 29.3 29.1 34.4 44.1 15.8 89.7 41.3 15.9 15.9 59.4 39.9 25.8 13.2 12.2 15.1 24.5 27.4 12.7 8.2 8.7 34.0 11.6 40.6 80.2 37.1 63.3 42.7 52.5 48.9 10.7 32.3 46.4 0.0 0.0 1.0 1.1 0.1 0.0 1.2 2.9 2.2 1.8 0.0 0.0 0.7 0.6 6.8 0.1 0.3 13.8 2.5 4.6 5.8 1.2 6.3 5.8 2.9 3.4 4.5 3.4 5.3 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583586 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 48.2" "Cell line enhanced" "Detected in many" "BEWO: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved 6400000 "HPA071245: " "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 18.3 4.1 18.7 2.1 16.6 1.5 7.7 27.3 39.2 2.3 1.8 25.6 1.2 2.3 5.0 4.2 12.7 11.7 3.1 2.5 15.1 7.8 6.4 1.6 3.2 1.9 19.6 18.2 48.2 9.5 1.3 0.8 5.9 14.0 3.3 1.7 1.7 2.4 6.7 1.4 13.0 2.9 4.8 23.1 5.4 3.6 17.9 16.6 0.0 1.8 2.2 4.1 2.9 2.8 1.2 1.0 5.0 0.9 1.0 0.8 0.2 4.7 3.1 9.9 10.8 9.3 6.4 33.5 6.9 4.4 6.9 6.4 17.6 1.6 0.1 8.9 5.6 11.2 11.1 1.7 3.2 2.7 7.4 1.4 10.0 8.3 6.6 2.4 0.2 2.0 3.5 5.2 1.8 5.1 8.7 2.0 3.7 4.5 1.1 0.4 22.9 3.2 14.7 9.0 1.7 0.6 9.2 11.9 3.4 6.5 10.3 7.7 8.5 2.8 3.9 13.7 6.0 10.1 10.4 0.8 1.6 1.4 8.3 15.8 8.2 2.6 0.9 0.8 0.6 0.5 0.6 0.7 0.6 0.8 0.3 1.2 0.7 0.7 5.0 1.0 0.5 1.0 0.5 0.2 18.7 16.6 27.3 32.7 15.1 7.8 19.6 18.2 14.0 16.6 TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029641 Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA029641: AB_2272535" "unprognostic (6.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (7.24e-2)" "prognostic unfavourable (1.49e-7)" "unprognostic (3.79e-1)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-2)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" "unprognostic (8.90e-2)" "unprognostic (2.98e-3)" 16.5 19.7 13.7 13.5 17.7 11.9 18.3 15.0 19.9 20.4 17.7 7.5 13.7 9.5 21.0 15.2 20.6 16.4 10.0 21.1 11.1 12.9 20.4 17.0 11.3 14.3 16.2 17.2 30.0 14.4 22.2 34.3 13.5 17.0 20.7 12.3 8.6 13.8 15.7 12.3 10.5 10.9 24.7 15.6 16.0 14.8 12.3 18.1 12.3 23.5 14.3 16.9 23.5 33.3 9.7 9.0 6.0 8.0 13.6 13.9 5.2 8.4 7.1 12.4 8.8 14.1 15.4 18.8 14.6 13.4 14.0 12.3 15.1 7.2 22.3 13.4 12.6 6.9 14.1 16.9 17.6 13.8 12.2 17.5 21.8 29.2 9.2 34.9 11.3 11.7 17.1 17.8 17.3 12.4 30.3 17.1 17.9 7.2 17.0 11.7 32.8 16.7 16.1 25.8 10.0 12.0 11.1 9.6 8.2 6.9 19.1 22.4 10.4 12.8 8.0 6.2 17.0 16.8 17.5 9.9 17.9 15.6 13.9 12.7 17.8 6.0 6.0 1.6 10.3 8.0 9.9 9.7 9.1 9.3 9.0 8.8 13.2 13.9 0.5 13.6 5.9 8.7 8.4 5.2 13.7 17.7 15.0 19.9 11.1 12.9 16.2 17.2 17.0 18.1 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 105.7;U-251 MG: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 19000 "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavourable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 38.4 18.5 7.0 17.4 9.8 17.2 24.8 9.0 13.4 16.1 26.9 5.7 45.7 17.2 10.9 19.4 23.6 15.7 18.3 22.5 7.7 7.8 11.0 67.1 16.0 7.4 6.6 8.9 20.4 31.4 5.1 16.0 21.5 9.1 13.9 26.9 7.8 43.9 62.5 19.4 12.4 33.4 28.8 7.1 8.1 23.0 37.7 3.7 5.6 12.4 13.5 15.3 24.4 16.7 8.3 5.6 8.1 1.6 6.2 16.1 4.8 29.9 2.1 6.0 4.8 29.2 23.4 4.1 44.1 16.2 34.0 27.8 5.7 14.1 1.1 9.9 33.8 5.2 6.7 12.8 56.1 4.7 10.1 5.3 6.9 11.1 13.7 9.0 3.6 10.8 6.1 37.3 105.7 20.8 29.9 12.4 45.4 5.5 5.2 5.8 4.4 9.8 4.7 11.7 14.6 5.3 3.5 6.4 6.7 19.2 12.0 10.2 5.9 10.3 35.3 17.2 15.8 43.2 68.8 20.8 7.3 9.9 9.8 4.2 10.8 1.0 1.6 8.1 13.0 1.6 16.1 8.3 7.9 13.3 3.4 6.5 7.6 9.5 1.6 6.2 0.8 5.6 3.9 4.8 7.0 9.8 9.0 13.4 7.7 7.8 6.6 8.9 9.1 3.7 UBE2A "HHR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574467-119591083 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (2.27e-3)" "prognostic favourable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 24.8 20.6 26.7 23.1 24.6 16.8 32.5 20.2 24.2 23.7 32.8 23.9 20.2 21.7 23.8 26.7 37.2 20.3 21.2 42.2 23.6 22.1 32.2 26.6 22.8 26.3 26.8 19.7 18.7 17.2 24.3 18.2 112.4 24.7 20.4 30.2 20.0 21.0 22.6 46.8 23.6 29.2 27.9 29.1 25.1 20.4 17.0 19.5 36.3 23.2 32.8 31.5 26.7 24.0 21.0 29.0 34.1 36.3 12.8 21.2 17.4 32.5 27.5 17.3 14.6 30.3 37.4 16.2 33.8 30.2 40.3 38.3 14.2 22.4 25.8 34.4 37.2 23.5 24.7 17.9 38.9 35.8 14.6 11.4 22.0 12.7 27.8 28.5 19.6 25.5 25.6 38.6 16.8 27.9 14.0 23.1 45.6 34.5 43.9 26.9 28.8 31.1 22.4 18.4 24.0 32.5 21.4 13.3 13.7 45.0 20.7 24.6 18.0 24.9 27.2 25.9 11.6 51.1 38.1 22.4 36.4 25.3 27.5 36.1 20.2 16.5 22.7 34.1 18.1 35.4 14.3 21.0 15.7 15.8 29.0 18.8 10.0 14.3 30.1 12.8 36.3 23.0 21.2 17.4 26.7 24.6 20.2 24.2 23.6 22.1 26.8 19.7 24.7 19.5 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371179-134391992 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 83.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 17.7 27.7 20.4 17.0 16.6 25.9 22.8 16.2 28.3 13.8 18.0 7.9 11.6 14.4 19.4 17.0 25.6 13.6 18.3 59.2 20.3 16.4 17.8 19.8 21.8 18.7 13.8 18.7 16.7 26.4 7.8 16.2 27.8 17.6 15.4 15.1 10.2 16.1 18.5 106.5 15.9 16.2 21.6 15.1 16.6 14.1 21.7 12.7 13.2 18.2 34.0 16.3 19.2 22.8 9.6 8.8 83.3 14.1 9.6 14.6 10.5 36.2 9.6 20.0 19.0 17.5 18.9 32.3 27.3 14.4 17.6 21.0 28.9 24.4 19.8 33.0 17.4 14.5 15.1 20.2 19.2 31.4 16.3 10.9 26.5 31.0 20.5 12.9 22.4 16.2 27.5 15.9 13.5 15.0 19.9 36.0 15.8 21.2 20.4 34.1 8.6 9.1 20.6 22.0 27.6 15.7 28.1 27.0 21.1 21.4 10.1 47.4 21.8 35.6 29.7 20.5 14.3 27.5 29.8 30.1 41.2 27.9 23.1 24.4 20.3 34.7 11.5 31.2 9.4 12.5 8.6 9.6 12.0 9.5 7.9 9.6 14.6 12.3 83.3 9.6 14.1 8.8 14.1 10.5 20.4 16.6 16.2 28.3 20.3 16.4 13.8 18.7 17.6 12.7 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 130.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: , HPA054975: " "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavourable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavourable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 3.1 2.3 0.4 24.0 0.9 25.1 4.3 0.4 0.7 3.8 9.5 0.4 0.8 7.8 2.0 2.6 25.6 0.6 3.2 2.8 0.5 0.4 2.1 2.1 4.6 15.6 0.6 0.5 1.2 1.3 0.0 0.6 12.6 0.9 1.3 11.7 0.7 3.7 0.6 1.0 8.3 10.0 3.5 1.2 11.6 7.0 15.3 0.5 130.8 0.8 17.6 26.3 2.8 7.8 1.2 0.9 2.7 0.6 2.4 10.0 4.2 39.2 28.8 52.0 24.9 1.4 3.2 29.9 31.2 15.8 51.4 36.9 94.6 45.4 41.6 30.6 14.8 38.8 0.2 33.4 52.5 17.7 27.4 12.8 22.1 24.8 0.4 18.3 32.2 1.0 3.6 34.8 34.1 25.0 0.2 35.4 42.3 64.6 30.2 5.2 31.2 69.0 32.1 47.1 0.2 17.3 13.6 30.0 25.0 49.1 36.0 19.7 36.3 27.0 9.1 46.1 40.3 31.3 60.3 11.2 0.3 46.4 28.0 13.1 43.7 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.2 2.3 0.9 0.2 0.2 0.1 2.7 2.4 0.6 0.5 10.0 4.2 0.4 0.9 0.4 0.7 0.5 0.4 0.6 0.5 0.9 0.5 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334975-58370753 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 41.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavourable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavourable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 8.2 10.6 8.1 10.0 7.9 17.1 7.5 7.7 9.0 6.3 7.3 5.5 4.8 4.7 8.5 5.5 8.2 5.5 6.4 25.6 7.6 7.2 5.5 5.4 7.0 13.7 8.1 6.7 5.9 4.8 5.3 7.4 6.8 7.4 6.5 7.9 3.5 6.4 5.0 74.9 4.6 5.8 8.8 8.4 11.0 5.6 3.2 8.4 5.5 6.0 25.1 7.1 9.5 10.0 3.7 7.2 41.0 13.7 2.8 3.5 7.1 10.6 5.8 10.8 13.9 22.2 17.9 7.0 7.0 12.0 8.1 11.9 11.7 9.2 0.0 11.1 10.5 9.7 20.9 10.2 11.4 11.0 12.3 2.8 2.1 6.7 14.6 8.4 6.8 20.7 11.5 8.4 15.7 16.1 5.5 4.5 10.9 3.3 9.0 9.4 13.2 9.1 7.6 9.8 5.9 12.1 6.2 8.2 11.0 13.8 23.3 11.2 8.5 5.7 12.9 3.1 10.9 10.6 7.7 11.5 8.9 9.4 9.8 17.5 3.5 2.8 13.7 6.2 2.4 9.5 2.8 3.3 2.9 3.0 7.2 3.7 3.0 2.3 41.0 2.8 7.9 3.0 3.5 7.1 8.1 7.9 7.7 9.0 7.6 7.2 8.1 6.7 7.4 8.4 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628433 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favourable (5.09e-5)" "prognostic favourable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavourable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavourable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 35.6 25.0 41.2 31.5 39.9 44.2 35.9 31.9 49.6 43.9 50.4 35.5 31.5 22.2 35.5 52.2 44.8 47.6 27.1 34.8 39.5 40.5 37.2 39.5 34.8 55.6 40.5 36.1 35.3 41.7 23.8 35.3 33.6 35.9 30.8 46.4 30.7 30.5 37.9 80.6 33.2 37.4 39.3 41.9 41.3 29.1 68.0 29.3 71.0 34.4 31.2 64.5 42.2 36.1 34.3 39.3 40.8 23.0 22.5 41.7 19.5 36.5 24.4 42.8 29.9 28.9 37.1 27.4 38.7 36.2 45.6 53.4 62.8 34.8 52.3 51.0 39.9 23.2 42.0 65.2 61.1 33.7 24.5 29.6 27.0 36.0 56.6 28.9 26.4 29.1 33.7 45.2 67.7 48.6 25.6 44.8 42.2 36.7 44.6 41.2 23.5 26.6 34.0 44.5 37.8 47.9 43.3 39.0 25.8 33.8 43.5 61.4 27.2 25.7 31.8 34.8 19.4 28.9 47.2 32.2 52.3 73.3 24.9 47.7 27.7 14.8 20.9 40.8 22.6 18.8 24.7 34.1 32.7 31.7 23.4 34.3 41.7 35.2 34.5 22.5 23.0 39.3 40.0 19.5 41.2 39.9 31.9 49.6 39.5 40.5 40.5 36.1 35.9 29.3 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favourable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 67.2 70.6 39.1 52.7 44.6 132.7 70.4 36.9 50.9 45.5 51.8 37.5 38.4 49.3 46.3 39.1 63.2 45.7 47.5 72.5 37.3 39.5 63.0 91.9 67.5 68.1 43.4 36.9 60.6 53.4 42.8 49.1 66.5 45.2 49.6 48.5 38.4 46.7 43.3 91.1 53.2 58.9 48.4 44.4 68.2 49.5 40.0 42.2 88.8 66.3 55.4 61.4 74.6 81.4 24.7 31.2 118.0 36.2 29.7 33.2 50.9 52.5 30.1 50.3 40.6 53.7 77.6 43.3 53.6 71.4 47.8 45.2 45.2 75.1 56.4 35.1 54.3 30.2 53.6 71.9 65.9 52.3 27.0 51.3 31.0 36.8 56.4 72.1 44.2 58.9 45.6 52.7 73.9 62.0 64.4 57.6 63.6 42.5 105.7 41.1 36.4 30.2 55.8 49.4 40.7 48.2 50.3 50.8 42.8 32.9 84.5 60.4 35.1 42.7 56.9 50.1 42.9 32.8 48.6 51.1 65.8 86.2 53.4 40.2 53.7 71.1 35.9 54.6 25.1 36.1 33.2 24.7 31.8 29.6 31.2 20.1 32.6 29.7 118.0 29.7 36.2 21.5 32.6 50.9 39.1 44.6 36.9 50.9 37.3 39.5 43.4 36.9 45.2 42.2 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926438-43956136 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.6" "Cell line enhanced" "Detected in all" "SH-SY5Y: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favourable (4.86e-4)" "prognostic favourable (5.77e-4)" "prognostic favourable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 10.1 13.1 14.7 5.0 13.3 4.5 9.1 13.8 17.4 8.8 7.6 11.4 7.9 5.3 7.5 11.2 8.0 9.0 7.2 23.8 14.2 10.0 12.7 15.3 8.4 5.3 12.1 9.4 7.9 17.4 8.7 6.9 5.9 11.9 8.7 6.2 8.1 10.6 9.1 48.6 9.4 5.3 10.3 12.8 7.3 6.5 5.1 6.1 2.7 9.6 16.1 5.7 7.7 6.5 10.7 11.8 12.9 20.5 7.7 14.0 6.7 3.7 3.2 1.9 8.9 9.2 3.7 1.5 1.9 4.6 2.4 3.1 1.7 4.5 3.7 5.2 4.9 4.3 2.5 2.0 3.6 8.1 4.1 3.9 4.9 4.3 3.4 8.5 8.0 2.9 4.3 2.7 4.1 2.9 4.3 7.6 3.2 2.4 5.0 4.9 4.3 4.1 3.1 2.7 5.6 5.0 4.6 7.3 24.7 3.9 7.9 2.9 3.9 2.6 2.5 1.6 4.9 3.3 5.4 11.0 8.2 1.8 4.7 11.2 8.7 6.3 11.7 12.9 9.3 18.4 9.5 10.3 11.6 10.5 11.8 10.7 14.0 11.5 1.1 7.7 20.5 10.2 9.4 6.7 14.7 13.3 13.8 17.4 14.2 10.0 12.1 9.4 11.9 6.1 UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805903-23891316 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030445, CAB073413" Approved Approved Nucleoplasm Nucleoplasm "CAB073413: , HPA030445: AB_10669599" "unprognostic (7.50e-2)" "unprognostic (2.78e-2)" "unprognostic (7.91e-3)" "unprognostic (7.13e-2)" "unprognostic (6.74e-3)" "unprognostic (1.74e-1)" "prognostic unfavourable (9.97e-7)" "unprognostic (3.69e-2)" "unprognostic (3.53e-2)" "unprognostic (1.34e-2)" "unprognostic (5.36e-3)" "unprognostic (2.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" 32.0 28.1 50.8 34.7 44.4 56.1 52.6 38.7 43.4 41.9 40.6 32.4 27.5 23.9 35.3 35.6 57.9 29.5 29.9 58.5 47.3 43.2 33.6 34.0 34.9 44.9 52.0 36.9 36.5 32.0 41.6 22.5 44.5 38.1 38.5 37.8 23.2 30.3 36.4 52.2 33.3 25.8 44.1 55.6 36.3 29.9 24.3 43.3 33.8 41.4 38.0 47.3 52.2 46.3 6.7 7.6 6.8 9.1 7.0 7.2 4.1 33.3 21.0 33.2 16.5 20.3 29.6 29.0 25.3 39.3 28.4 38.1 15.8 37.0 29.5 21.4 24.3 10.8 39.1 31.2 37.3 35.7 43.7 40.8 15.8 19.3 29.2 40.2 21.8 27.9 29.5 36.2 48.7 45.1 28.5 33.0 22.7 17.2 28.2 43.7 48.7 53.9 31.4 14.5 85.0 44.2 23.8 9.6 34.5 22.6 21.0 36.4 23.6 53.2 29.3 20.9 25.9 15.4 18.7 27.5 16.3 58.5 22.5 38.6 16.1 2.4 8.4 6.8 4.5 9.1 6.5 6.5 5.4 3.8 7.3 6.7 7.2 4.3 3.3 7.0 5.8 7.6 3.9 4.1 50.8 44.4 38.7 43.4 47.3 43.2 52.0 36.9 38.1 43.3 UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.2;intermediate monocyte: 17.8;memory B-cell: 12.3;myeloid DC: 20.9;naive B-cell: 14.8;non-classical monocyte: 18.3;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 6 "B-cells: 14.8;dendritic cells: 27.1;monocytes: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm Nucleoplasm "CAB073417: , HPA003303: AB_1858521, HPA028872: AB_10966277, HPA030445: AB_10669599" "unprognostic (2.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "unprognostic (3.68e-3)" "unprognostic (3.74e-2)" "unprognostic (1.70e-1)" "unprognostic (9.19e-3)" "unprognostic (3.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.20e-1)" "unprognostic (4.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.44e-2)" "unprognostic (2.68e-2)" "unprognostic (3.11e-2)" "unprognostic (6.11e-3)" 22.7 11.4 19.2 12.0 23.3 7.6 15.9 18.8 32.7 22.4 14.5 20.8 7.5 5.9 17.7 31.9 19.7 12.0 18.5 23.4 21.3 21.8 19.1 15.8 16.7 17.7 14.1 19.7 19.0 9.8 15.5 14.4 9.0 20.9 18.2 6.4 8.4 11.2 17.0 32.0 14.8 7.2 22.4 17.6 15.9 11.1 17.8 13.3 14.8 16.8 11.1 14.5 17.0 16.2 14.8 27.1 0.4 18.3 0.8 3.6 5.2 16.7 6.0 16.0 0.3 14.2 15.9 14.5 10.6 18.1 10.0 14.1 1.7 13.8 14.6 7.3 9.3 1.6 11.6 16.5 12.9 0.1 11.6 0.0 7.2 2.0 10.2 0.0 11.7 12.5 17.4 14.3 24.2 9.6 0.8 15.6 9.0 2.6 7.6 3.3 11.3 8.8 16.0 6.2 16.7 9.7 0.4 4.1 8.5 11.7 6.9 0.2 14.7 9.7 8.3 9.9 14.0 6.6 12.0 15.0 4.9 21.5 9.3 6.6 2.7 0.0 15.2 0.0 0.2 17.8 0.3 12.3 0.5 0.2 20.9 14.8 3.6 1.3 0.4 0.8 18.3 27.1 0.2 5.2 19.2 23.3 18.8 32.7 21.3 21.8 14.1 19.7 20.9 13.3 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavourable (8.08e-5)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavourable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 29.1 23.9 35.6 21.1 33.0 20.1 49.7 37.4 62.9 30.4 25.2 18.6 19.8 23.0 26.6 29.2 23.1 29.7 35.9 37.8 43.9 32.5 36.0 29.6 28.5 37.6 31.5 31.9 27.7 29.9 42.9 21.6 23.9 30.5 20.9 27.8 24.6 26.3 22.7 76.8 28.1 26.2 24.1 41.3 20.4 28.3 28.1 21.5 30.9 37.4 27.8 23.0 31.8 23.0 7.7 29.7 25.6 16.9 8.5 12.0 9.6 17.2 7.9 113.1 3.9 33.6 43.4 18.0 23.2 29.4 19.6 24.5 8.5 21.1 8.5 20.4 31.6 7.4 68.2 23.8 35.3 20.8 20.6 29.5 10.7 23.6 16.2 13.6 14.1 17.1 22.2 17.1 16.6 25.8 15.0 16.0 48.1 9.5 24.8 12.8 21.6 37.4 24.3 11.5 20.3 33.3 15.3 19.7 22.0 10.1 10.7 9.5 5.8 20.2 23.7 38.2 25.2 22.3 27.0 14.0 8.9 24.0 37.7 5.4 21.1 13.0 14.0 25.6 9.3 12.3 11.1 7.7 7.3 12.0 9.2 4.9 7.8 8.5 13.2 8.5 16.9 29.7 2.8 9.6 35.6 33.0 37.4 62.9 43.9 32.5 31.5 31.9 30.5 21.5 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037444 Approved Approved Cytosol Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavourable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 14.5 18.4 21.3 13.6 17.6 19.9 17.2 12.2 19.8 16.7 15.8 17.7 12.3 13.6 14.7 32.2 25.0 11.0 16.3 34.6 20.2 21.6 14.6 24.1 12.9 26.4 23.4 10.1 10.4 62.8 16.3 13.2 22.2 24.2 14.9 19.6 11.4 15.3 18.2 32.1 10.3 17.9 20.2 20.2 14.6 15.1 13.9 16.8 15.8 32.9 17.4 17.7 18.7 16.4 10.9 23.1 35.6 30.0 39.9 29.1 24.6 13.7 7.9 18.1 18.5 23.6 28.8 25.6 13.0 18.6 14.7 15.1 8.6 8.8 7.1 4.7 29.0 11.7 20.5 28.2 22.9 10.8 8.0 9.8 10.0 27.9 29.7 4.1 23.1 16.5 46.6 19.3 29.5 25.9 29.8 4.6 26.5 20.6 11.1 18.0 19.9 12.0 13.5 12.0 12.7 22.1 5.8 12.1 18.1 15.2 11.5 23.9 10.4 17.1 16.1 16.2 14.2 18.3 13.9 5.7 4.4 13.9 19.2 12.5 11.9 35.6 21.0 25.2 29.1 27.6 11.5 10.9 19.9 17.6 18.6 10.1 18.6 18.8 15.6 39.9 30.0 23.1 20.5 24.6 21.3 17.6 12.2 19.8 20.2 21.6 23.4 10.1 24.2 16.8 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA045681: , HPA050551: " "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 10.8 11.1 12.6 17.8 13.5 14.3 11.2 11.6 15.3 13.0 19.4 17.8 8.9 11.9 13.3 8.5 27.4 9.2 9.7 26.9 13.5 11.2 14.6 17.7 8.9 18.7 15.2 9.7 9.1 17.1 12.0 6.0 11.4 14.5 14.0 13.3 8.8 11.9 12.0 95.6 14.1 16.6 14.6 19.4 15.0 11.9 11.8 13.6 21.3 12.5 20.7 23.3 17.7 16.5 23.7 13.1 24.4 11.5 20.5 20.6 13.1 21.2 23.0 21.5 15.7 17.6 18.7 30.7 20.7 16.7 19.8 17.4 15.8 10.9 33.3 21.8 20.3 23.0 26.7 19.2 31.9 17.5 21.8 12.4 12.2 18.0 17.3 18.0 23.6 15.9 28.8 18.7 27.3 26.4 21.8 36.1 16.2 9.5 22.9 16.6 23.7 12.0 29.8 11.4 30.4 23.0 14.0 9.3 17.4 19.5 17.0 16.1 16.7 11.8 19.8 19.9 15.2 23.2 23.1 14.0 16.4 47.1 15.3 16.9 15.2 8.1 10.3 24.4 15.4 10.8 20.6 23.7 20.1 20.1 13.1 15.5 20.2 20.5 18.6 20.5 11.5 9.6 18.3 13.1 12.6 13.5 11.6 15.3 13.5 11.2 15.2 9.7 14.5 13.6 UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44802019 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved "HPA003332: AB_1858525" "unprognostic (7.58e-2)" "unprognostic (5.41e-2)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (6.30e-2)" "unprognostic (4.67e-2)" "unprognostic (5.99e-2)" "unprognostic (3.79e-3)" "unprognostic (6.93e-3)" "unprognostic (7.02e-2)" "unprognostic (1.40e-2)" "unprognostic (6.98e-3)" "prognostic unfavourable (7.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" 30.9 20.7 18.9 22.8 20.9 25.8 21.1 21.0 21.6 18.9 22.7 20.5 19.8 14.9 22.2 18.4 19.3 20.5 18.0 37.1 18.3 17.1 26.2 27.3 19.7 19.7 19.0 17.0 18.1 30.2 22.1 26.0 17.0 18.9 18.3 16.5 18.6 15.4 28.3 50.8 15.6 16.9 28.5 17.8 23.8 20.2 14.0 18.8 18.4 20.6 18.7 21.6 20.9 18.9 11.9 17.5 5.9 13.0 14.0 17.3 12.1 15.6 3.2 10.8 13.9 14.8 6.5 9.9 11.1 8.6 9.7 10.6 12.4 2.1 20.3 10.6 11.0 6.3 15.8 13.4 8.8 19.0 16.3 33.0 2.3 10.0 11.7 24.3 5.7 10.4 15.9 13.0 12.7 15.2 30.6 14.2 13.3 7.0 26.9 2.9 28.1 14.0 22.1 10.0 18.1 12.7 8.4 12.6 22.4 15.6 5.1 16.0 4.9 21.2 10.8 9.4 6.7 8.7 17.9 22.3 43.8 20.1 9.4 28.8 11.0 2.3 11.6 5.9 16.0 11.8 17.3 11.8 14.7 16.2 12.5 11.9 15.7 16.6 3.6 14.0 13.0 17.5 14.6 12.1 18.9 20.9 21.0 19.3 18.3 17.1 19.0 17.0 18.9 18.8 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952949 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Supported Mitochondria Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavourable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 29.0 49.9 31.1 16.6 31.0 22.5 24.5 36.1 30.2 31.1 27.3 33.2 26.6 15.2 35.5 25.3 32.1 29.4 26.6 61.0 26.4 25.4 27.6 28.1 26.3 17.5 28.1 23.4 27.6 52.3 41.8 29.5 37.9 33.3 24.1 16.8 22.9 28.5 28.8 46.3 21.3 16.5 31.5 26.2 19.1 22.7 24.7 29.5 24.7 37.7 23.6 29.5 25.5 34.3 6.1 3.7 7.8 2.2 1.3 6.5 1.9 22.7 12.3 14.6 14.8 36.4 31.3 25.3 21.1 27.2 12.9 14.4 6.6 24.4 9.4 26.4 20.7 17.3 12.5 22.4 16.9 11.6 6.6 3.2 18.1 7.9 28.6 6.5 10.4 42.0 29.8 17.4 28.0 25.1 7.7 27.4 19.9 8.1 8.6 7.1 23.0 14.7 6.7 7.5 20.1 27.0 29.9 5.6 16.9 19.3 43.2 11.3 4.5 6.4 25.5 14.1 7.1 19.8 20.9 25.0 18.0 15.6 28.0 7.8 13.7 3.5 2.2 5.1 4.7 1.7 6.4 3.8 4.7 4.2 2.0 6.1 6.0 6.4 7.8 1.3 2.1 3.7 6.5 1.9 31.1 31.0 36.1 30.2 26.4 25.4 28.1 23.4 33.3 29.5 UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352848 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.5;Karpas-707: 54.0;U-266/70: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced "CAB073419: , HPA003509: AB_1858531" "unprognostic (1.82e-1)" "unprognostic (3.20e-2)" "unprognostic (1.55e-3)" "prognostic favourable (2.87e-4)" "unprognostic (3.41e-1)" "unprognostic (7.93e-3)" "prognostic unfavourable (6.90e-5)" "unprognostic (1.19e-1)" "unprognostic (9.36e-2)" "prognostic favourable (7.43e-4)" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "prognostic unfavourable (1.11e-4)" "unprognostic (5.11e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (9.38e-2)" 18.7 17.3 14.6 47.1 15.4 52.7 28.2 19.1 13.6 18.8 25.9 11.3 24.4 28.0 19.5 18.4 19.2 18.0 19.9 17.1 14.4 14.7 18.7 33.5 20.4 52.0 17.0 9.5 17.2 46.1 11.5 13.6 27.5 13.0 22.9 26.3 10.7 42.1 33.2 12.5 11.3 36.3 17.9 18.9 45.8 24.4 17.7 14.4 42.5 17.6 16.4 47.7 21.7 21.4 20.7 23.7 15.9 17.8 6.4 6.4 6.1 8.1 2.8 7.9 10.1 8.3 10.8 0.0 13.0 11.5 8.1 8.9 4.6 5.1 62.5 7.3 13.4 3.3 5.1 7.5 13.2 8.7 8.0 11.3 3.7 7.6 22.1 14.2 7.4 8.2 7.6 6.7 11.6 18.0 9.1 54.0 9.4 5.0 5.9 10.9 2.7 4.1 23.3 10.2 29.9 10.1 5.7 4.0 8.1 5.5 12.2 12.0 4.8 31.6 12.0 4.5 4.3 8.0 9.9 60.7 30.1 17.1 8.9 10.3 7.4 10.3 6.6 12.3 3.4 11.1 4.0 20.7 4.6 4.2 6.5 13.4 4.3 3.9 15.9 6.4 17.8 23.7 6.4 6.1 14.6 15.4 19.1 13.6 14.4 14.7 17.0 9.5 13.0 14.4 UBE2J2 "NCUBE2, Ubc6p" ENSG00000160087 "Ubiquitin conjugating enzyme E2 J2" Q8N2K1 1 1253909-1273885 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.25e-1)" "unprognostic (3.04e-2)" "unprognostic (1.88e-2)" "unprognostic (4.46e-2)" "unprognostic (1.67e-3)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (9.57e-2)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic unfavourable (2.00e-4)" "unprognostic (2.09e-2)" "unprognostic (6.19e-2)" "unprognostic (1.87e-1)" "unprognostic (3.46e-2)" 24.4 22.2 17.5 21.6 17.1 19.4 33.0 23.8 24.9 17.8 22.0 17.9 19.9 22.0 22.9 21.4 25.2 21.8 20.7 21.2 17.5 17.1 21.6 27.3 17.4 27.4 15.9 15.4 19.4 36.3 14.4 22.8 22.6 15.9 16.9 16.2 18.7 24.2 20.2 29.8 23.2 23.6 19.3 13.1 25.2 22.2 68.3 12.8 26.1 22.8 21.7 23.8 18.3 19.3 24.5 22.3 39.6 23.0 22.0 25.3 17.7 25.2 10.5 15.0 14.4 12.2 12.5 11.7 19.6 15.5 26.8 19.6 18.7 18.5 13.6 20.9 18.0 18.5 15.2 19.5 21.3 23.1 27.3 20.5 20.6 16.8 23.7 18.8 19.7 11.7 10.9 21.0 15.6 18.8 28.3 13.5 15.5 12.6 27.2 21.1 16.2 26.4 25.4 14.0 22.5 13.9 8.6 55.5 27.4 13.5 29.1 30.9 14.9 21.4 15.3 16.2 15.6 18.7 20.0 29.9 29.0 38.1 20.9 29.9 12.8 38.2 23.0 39.6 22.0 22.2 20.1 24.5 23.4 22.8 22.3 21.7 21.2 20.9 32.6 22.0 21.3 20.8 25.3 17.7 17.5 17.1 23.8 24.9 17.5 17.1 15.9 15.4 15.9 12.8 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698044-39782792 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Supported "Intermediate filaments,Actin filaments,Cytosol" 150000 Cytosol "Intermediate filaments, Actin filaments" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavourable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 27.2 21.8 27.0 21.2 27.6 17.3 21.6 38.6 40.7 17.0 33.2 11.8 14.1 29.1 19.9 18.5 29.9 14.9 18.5 28.1 27.7 26.8 26.6 44.5 17.1 17.9 24.1 26.4 16.9 15.8 18.9 26.9 29.8 25.2 19.7 24.0 13.4 18.4 17.3 31.8 22.0 24.6 18.8 19.2 16.9 29.3 16.0 15.9 21.3 23.6 19.7 18.8 22.8 20.4 17.6 23.7 20.6 19.9 10.9 14.1 8.9 23.8 24.5 13.2 12.5 8.3 7.8 22.5 32.9 7.0 8.8 9.3 37.0 24.6 29.8 29.0 9.2 10.1 25.4 14.3 14.2 20.0 18.2 38.6 24.8 32.0 10.4 41.4 21.9 7.3 16.2 12.4 13.4 11.5 39.2 10.7 9.1 23.1 28.9 23.0 17.6 18.7 17.1 39.7 11.2 12.3 33.3 27.4 12.1 24.6 9.3 14.7 12.0 13.9 31.5 13.8 29.3 16.4 30.2 15.2 44.3 32.8 7.2 26.6 16.1 13.9 16.6 20.6 13.5 14.3 12.7 17.6 14.1 12.6 16.6 12.5 10.7 12.0 13.3 10.9 19.9 23.7 13.7 8.9 27.0 27.6 38.6 37.7 27.7 26.8 24.1 26.4 25.2 15.9 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol 8800000 "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: " "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavourable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favourable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 27.8 34.9 34.8 23.5 29.6 31.3 24.9 25.5 36.9 25.9 27.7 38.4 22.8 26.4 25.6 29.2 38.0 26.9 23.0 33.0 30.7 30.8 27.4 36.0 23.5 32.5 34.3 33.1 24.3 23.9 24.3 21.7 30.1 36.9 27.5 31.7 29.3 30.6 26.7 43.5 23.9 34.4 33.1 36.2 28.5 25.1 35.7 22.6 25.3 25.0 32.4 33.9 28.4 22.2 34.7 49.9 46.1 45.8 34.6 46.9 54.9 24.4 14.1 20.7 16.1 22.6 20.2 11.9 20.6 23.6 26.6 25.3 16.0 11.8 23.1 10.4 27.3 21.0 27.5 22.4 26.5 23.0 29.7 26.7 13.8 19.1 15.1 38.1 19.3 17.8 19.6 19.2 14.0 29.8 107.9 12.4 28.6 18.0 19.8 27.6 15.2 14.9 16.2 31.1 6.3 24.9 19.7 18.6 13.8 16.4 20.7 18.9 12.9 21.1 21.3 18.8 24.2 15.9 21.0 12.1 19.5 21.1 25.5 17.7 17.8 30.8 40.4 46.1 41.4 45.8 38.8 34.7 39.6 44.2 49.9 31.2 34.5 41.6 34.2 34.6 37.6 48.4 46.9 54.9 34.8 29.6 25.5 36.9 30.7 30.8 34.3 33.1 36.9 22.6 UBE2L5 UBE2L5P ENSG00000236444 "Ubiquitin conjugating enzyme E2 L5" 13 30422488-30428616 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "testis: 31.5" "Low cell line specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA045609, HPA062415" Approved Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: " "unprognostic (2.09e-1)" "unprognostic (1.18e-2)" "unprognostic (8.01e-3)" "unprognostic (6.41e-4)" "unprognostic (1.78e-1)" "unprognostic (7.13e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-3)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (3.50e-2)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (2.44e-2)" "unprognostic (8.75e-2)" 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.3 0.3 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.2 0.2 0.1 0.2 0.5 0.3 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 31.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 1.9 2.7 3.6 1.9 2.0 2.8 0.6 0.3 1.2 1.6 0.6 0.6 0.6 1.1 0.6 0.4 0.2 0.0 3.0 1.4 0.5 1.3 0.6 0.8 0.4 1.1 2.4 0.6 0.4 0.8 0.2 0.2 0.7 1.5 0.2 0.3 0.6 0.2 0.9 0.7 1.3 0.3 0.0 1.6 2.5 1.3 0.2 0.4 0.6 0.4 0.9 1.5 1.2 0.3 0.4 0.1 1.8 0.6 2.4 0.0 0.7 0.5 0.7 1.1 1.5 0.3 1.6 1.0 0.9 0.4 1.8 1.1 1.9 1.4 3.6 1.2 3.2 1.5 1.6 1.5 1.7 1.4 2.0 2.7 1.9 1.6 1.9 2.0 2.8 UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol 34000 Cytosol "CAB073407: , HPA003328: AB_1858539" "prognostic favourable (6.75e-4)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-2)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-3)" "prognostic unfavourable (4.88e-4)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (6.42e-2)" 31.1 31.0 32.0 34.1 28.6 30.4 40.4 18.2 25.6 23.3 19.1 17.0 17.1 19.0 21.9 30.0 19.9 28.6 27.4 18.4 23.5 27.4 28.3 55.1 50.5 45.0 28.9 20.4 27.1 21.8 17.9 18.5 21.7 25.8 26.0 18.8 18.7 42.8 22.2 10.1 15.9 23.5 28.3 23.6 47.9 21.4 7.7 23.6 44.0 33.6 15.1 34.4 33.0 49.0 49.2 53.6 113.6 83.4 61.2 66.4 112.6 8.7 4.4 14.9 4.7 31.6 39.4 1.6 5.1 30.4 45.1 58.7 1.6 22.8 28.0 18.0 15.5 7.0 6.4 16.8 9.6 25.5 0.2 27.6 0.0 6.2 58.6 6.3 9.1 42.1 3.9 21.1 5.8 14.2 1.2 19.4 8.1 11.1 42.5 15.2 3.9 5.6 37.6 9.1 19.2 12.1 9.8 0.3 7.8 10.2 0.8 22.3 11.2 3.2 5.2 9.4 3.3 7.1 1.6 26.5 26.7 0.5 26.3 16.0 2.0 56.7 71.6 62.5 51.2 83.4 56.4 49.2 53.4 53.4 53.6 39.7 46.5 48.8 113.6 61.2 68.3 34.0 66.4 112.6 32.0 28.6 18.2 25.6 23.5 27.4 28.9 20.4 25.8 23.6 UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93442262 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA044976 Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" 4600000 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: " "unprognostic (1.74e-2)" "unprognostic (5.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "prognostic unfavourable (2.41e-4)" "unprognostic (8.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.28e-3)" "unprognostic (1.07e-1)" "unprognostic (9.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (1.30e-3)" 24.7 25.0 29.0 28.7 39.1 29.0 21.2 29.2 44.3 18.4 26.6 15.6 15.1 20.7 23.2 20.0 30.4 19.7 17.0 27.7 31.0 33.7 25.4 22.3 19.3 36.1 27.6 34.5 17.4 17.6 13.9 18.2 24.2 34.9 23.4 22.6 13.7 18.0 18.5 35.7 19.1 20.4 21.3 24.6 21.5 19.3 83.7 17.4 32.2 15.5 16.8 35.1 22.7 18.8 53.8 35.5 29.9 39.2 29.5 57.3 51.9 35.8 26.0 43.9 28.1 17.0 16.9 30.6 50.2 26.8 40.3 33.8 46.2 15.6 73.0 11.4 29.3 28.6 48.4 36.8 38.4 60.7 25.1 49.1 14.3 40.7 21.7 58.6 32.8 17.7 15.2 24.0 30.0 31.0 54.5 11.4 41.8 29.5 57.8 54.5 57.1 36.4 45.0 35.6 35.7 33.5 54.3 42.9 39.1 26.5 31.2 24.5 40.8 36.1 32.0 27.3 22.8 24.6 36.1 19.7 53.3 62.0 10.7 31.3 33.3 29.9 27.1 28.9 31.7 35.4 36.9 53.8 40.2 39.2 35.5 38.6 36.0 34.4 8.2 29.5 39.2 26.7 57.3 51.9 29.0 39.1 29.2 44.3 31.0 33.7 27.6 34.5 34.9 17.4 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389451-76453206 "Enzymes, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" 1600000 Nucleoplasm "Nuclear bodies" "HPA023605: " "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavourable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 8.5 8.5 13.8 10.2 22.6 19.2 7.3 25.2 38.1 9.4 7.2 12.2 7.4 9.9 9.9 8.2 11.7 10.8 7.1 15.4 12.7 15.2 6.5 7.6 6.6 12.8 11.7 14.6 13.9 14.4 16.4 14.3 9.8 30.6 9.4 6.0 10.5 13.4 10.4 23.0 15.2 8.2 8.0 8.0 10.8 10.8 18.1 12.2 10.9 15.8 6.9 9.2 8.6 9.1 4.9 4.1 2.7 1.7 1.5 4.0 1.9 12.9 14.9 15.2 18.7 9.6 6.1 13.2 6.1 6.6 9.9 9.7 12.9 6.6 18.4 4.3 7.5 13.1 17.7 10.5 7.1 5.2 21.8 18.6 9.7 21.6 7.9 11.2 11.3 6.2 8.6 9.5 8.2 13.4 15.5 16.4 5.0 10.7 22.2 13.0 14.1 20.0 22.0 19.6 20.2 4.4 11.1 22.6 20.3 8.9 23.2 12.2 13.3 8.1 7.9 11.7 11.0 9.9 10.0 13.6 4.4 15.5 12.8 9.4 7.6 0.0 1.7 2.7 4.0 0.8 2.2 2.6 2.6 2.0 1.0 4.9 2.1 3.0 0.4 1.5 1.0 4.1 2.3 1.9 13.8 22.6 25.2 38.1 12.7 15.2 11.7 14.6 30.6 12.2 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome Nucleoplasm Centrosome "HPA063368: " "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavourable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavourable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favourable (1.86e-5)" "unprognostic (1.04e-2)" 17.3 18.7 26.5 16.2 29.4 24.2 19.4 26.4 29.0 20.0 21.2 18.7 8.2 16.2 18.3 25.4 20.9 21.8 18.2 17.6 24.5 25.8 25.7 27.4 23.0 26.3 22.8 21.0 21.7 27.2 21.4 29.3 24.5 27.2 21.4 25.7 18.5 19.0 19.8 19.1 21.6 21.4 21.9 19.1 26.0 20.5 30.0 22.0 25.1 21.0 14.0 29.9 19.3 18.5 3.2 5.1 8.1 3.1 4.7 6.2 1.6 18.0 15.7 22.2 16.9 22.8 23.6 19.2 17.9 27.4 23.2 18.8 17.6 19.4 22.3 25.9 25.0 15.8 26.1 20.8 20.0 22.4 16.5 17.7 14.0 17.0 28.8 28.7 28.5 22.7 27.6 18.7 21.7 29.7 14.8 27.7 29.5 28.0 17.5 21.1 30.3 26.7 20.2 15.5 23.4 25.4 19.3 22.6 31.6 18.2 34.3 29.4 20.9 43.8 20.6 15.0 16.8 17.7 19.1 33.8 25.0 29.5 16.8 20.3 22.7 8.1 2.8 5.6 4.8 3.1 4.3 3.0 4.5 5.9 2.5 3.2 5.0 5.7 4.4 4.7 2.6 5.1 6.2 1.6 26.5 29.4 26.4 29.0 24.5 25.8 22.8 21.0 27.2 22.0 UBE2Q2 DKFZp762C143 ENSG00000140367 "Ubiquitin conjugating enzyme E2 Q2" Q8WVN8 15 75843285-75901078 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "unprognostic (1.28e-1)" "unprognostic (1.66e-2)" "unprognostic (2.45e-2)" "unprognostic (4.28e-2)" "unprognostic (8.82e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-3)" "unprognostic (1.32e-1)" "unprognostic (6.38e-2)" "prognostic favourable (5.73e-4)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-3)" "unprognostic (1.01e-3)" "unprognostic (1.92e-1)" "unprognostic (1.69e-2)" "unprognostic (5.92e-2)" 17.8 19.8 15.6 18.8 10.9 22.2 41.1 11.6 14.4 20.0 25.2 12.4 12.9 6.0 17.6 15.5 24.7 11.8 22.7 25.1 15.0 16.0 16.5 6.3 21.0 25.9 19.8 10.3 17.2 13.8 7.7 12.6 34.8 12.0 22.3 13.5 13.0 20.1 15.0 26.4 11.0 11.1 42.9 23.1 15.1 14.7 13.5 11.6 27.6 21.4 22.3 11.2 40.2 35.7 6.1 4.2 18.0 6.9 10.6 9.6 4.8 9.6 14.8 13.8 9.8 19.3 25.5 20.7 21.4 24.2 14.2 16.3 7.7 13.3 9.6 15.9 30.8 7.9 24.7 14.1 17.5 9.9 10.0 12.0 9.0 10.4 21.3 12.6 7.0 17.7 16.4 10.0 14.8 19.6 4.5 14.5 30.2 7.4 10.2 11.6 9.7 10.7 12.2 21.7 3.8 22.6 15.4 12.0 9.4 18.4 17.3 23.3 11.1 17.2 26.0 17.7 16.2 11.8 7.5 15.8 27.7 7.6 7.1 19.3 10.7 18.0 4.7 15.5 7.2 5.3 9.0 6.1 9.6 7.6 4.2 4.8 7.7 6.4 0.7 10.6 6.9 1.5 6.1 4.8 15.6 10.9 11.6 14.4 15.0 16.0 19.8 10.3 12.0 11.6 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448623-6494909 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 28.1;heart muscle: 11.3;retina: 8.2;seminal vesicle: 8.6;skeletal muscle: 21.3" "Cell line enhanced" "Detected in some" "Karpas-707: 17.8;PC-3: 14.9;SCLC-21H: 13.9;U-266/70: 33.3;U-266/84: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "eosinophil: 1.2" "Lineage enhanced" "Detected in single" "granulocytes: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favourable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 0.6 2.3 8.6 0.8 4.2 0.3 0.9 20.7 28.1 1.0 1.8 1.0 0.5 0.7 1.4 1.8 1.0 0.5 0.8 11.3 12.6 8.2 2.6 1.1 0.4 0.7 5.2 4.6 3.6 0.8 0.3 1.3 0.3 8.7 3.1 0.8 8.2 1.0 8.6 21.3 2.4 1.0 1.3 1.4 0.4 2.2 0.9 0.0 0.0 1.9 2.0 0.5 0.5 0.9 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.8 0.0 3.0 0.0 0.0 0.2 14.9 0.1 0.0 6.6 0.0 0.0 13.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 33.3 29.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 4.2 20.7 19.4 12.6 8.2 5.2 4.6 8.7 0.0 UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817567-33920404 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 21.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061000 Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA061000: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavourable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" 26.1 19.7 29.4 19.7 26.8 13.9 39.3 23.7 32.3 25.6 24.1 27.9 16.3 28.0 26.1 18.4 25.3 22.3 21.8 29.2 25.5 20.3 22.1 34.5 23.0 27.1 30.5 23.2 29.8 44.5 15.7 13.9 24.6 21.6 21.0 21.4 19.3 18.7 20.8 56.1 28.1 25.7 28.5 24.2 21.6 20.8 34.5 29.6 36.7 19.5 22.5 25.7 35.8 30.5 3.3 4.2 21.9 11.6 5.0 2.1 2.4 16.3 18.0 34.6 15.0 19.1 31.2 10.6 14.6 20.3 17.1 17.1 14.4 12.3 14.0 6.0 20.3 7.3 18.1 16.6 18.8 23.0 9.6 12.0 19.8 18.3 27.2 14.3 13.1 26.4 24.7 14.0 26.5 28.7 11.3 15.1 16.9 9.5 26.9 37.6 19.7 14.9 25.0 10.5 7.2 18.1 12.4 16.2 19.5 17.0 15.2 10.9 13.4 17.4 21.4 16.5 15.0 11.4 13.5 9.6 9.0 19.5 15.8 8.3 35.5 12.4 7.5 4.1 2.0 7.5 1.3 3.1 1.9 1.6 4.2 3.3 1.9 1.7 21.9 5.0 11.6 2.6 2.1 2.4 29.4 26.8 23.7 32.3 25.5 20.3 30.5 23.2 21.6 29.6 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407777 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0;lymphoid tissue: 60.2;testis: 69.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: " "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavourable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavourable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 10.2 9.2 18.0 19.5 15.9 68.0 4.7 11.4 21.6 6.1 12.0 9.1 4.5 8.4 7.1 7.2 17.1 6.0 9.7 18.0 18.7 18.1 5.9 5.6 6.3 22.9 13.7 14.4 6.4 6.0 3.7 12.9 9.8 12.9 7.0 7.1 6.2 4.9 5.3 7.3 6.2 7.3 10.7 15.3 11.0 10.6 69.4 8.2 60.2 5.9 14.3 21.1 10.0 7.1 4.5 3.1 6.0 1.9 0.6 2.6 0.3 59.4 32.2 28.3 22.6 1.8 2.6 5.0 48.4 14.7 29.9 27.3 21.8 21.3 57.9 20.1 12.1 17.5 28.4 12.6 13.3 45.3 94.2 34.6 18.5 7.0 5.4 41.3 33.7 2.8 3.5 22.0 21.3 11.7 34.3 40.6 18.7 15.7 56.0 21.5 71.1 54.7 49.3 21.8 20.8 8.0 12.7 72.0 39.0 61.7 15.3 27.4 10.9 22.5 17.9 18.1 51.3 15.3 115.2 32.7 78.5 67.9 18.9 29.3 65.3 1.1 1.9 2.9 1.8 1.5 1.2 4.5 2.6 2.6 1.5 1.6 2.5 1.5 6.0 0.6 0.9 3.1 1.0 0.3 18.0 15.9 11.4 21.6 18.7 18.1 13.7 14.4 12.9 8.2 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavourable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favourable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavourable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 1.9 4.2 9.6 8.5 12.2 20.8 3.9 4.4 13.5 3.5 11.2 0.7 17.2 7.5 4.3 4.1 10.3 2.9 3.0 8.8 8.8 11.2 4.5 2.8 3.1 15.2 8.7 8.2 1.3 0.9 2.4 3.1 8.7 8.2 2.2 13.9 1.9 2.8 7.0 13.1 4.5 6.9 8.1 3.4 6.7 4.0 16.0 1.8 46.8 2.6 12.8 15.3 6.3 4.5 9.0 3.6 1.7 8.6 1.1 11.1 2.9 30.3 29.0 43.2 20.4 4.0 7.4 24.7 33.2 18.6 38.0 26.8 20.6 37.3 35.4 13.2 12.1 24.8 39.9 19.5 34.3 32.1 22.8 21.6 15.8 23.5 1.8 25.9 26.4 2.6 4.7 29.9 12.4 22.0 27.3 29.3 29.7 28.3 46.3 33.0 16.7 14.8 35.9 46.0 30.8 14.5 14.6 34.0 34.7 23.2 28.6 11.1 30.1 16.4 10.8 17.1 27.4 29.9 39.4 14.9 29.0 45.1 17.0 27.0 35.5 0.0 0.8 1.7 3.7 2.4 2.8 9.0 5.0 3.9 1.7 6.3 7.3 8.0 0.0 1.1 8.6 3.6 11.1 2.9 9.6 12.2 4.4 13.5 8.8 11.2 8.7 8.2 8.2 1.8 UBE2U MGC35130 ENSG00000177414 "Ubiquitin conjugating enzyme E2 U (putative)" Q5VVX9 1 64203627-64267368 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 31.8" "Cell line enhanced" "Detected in some" "EFO-21: 2.3;U-266/84: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 19.5" "unprognostic (9.44e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (4.01e-2)" "unprognostic (3.63e-1)" "unprognostic (7.69e-2)" 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli Nucleoli "HPA045161: AB_10960706, HPA073181: " "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" 15.2 14.2 13.5 13.3 21.8 17.5 13.4 18.9 24.4 12.0 9.8 11.3 11.0 7.9 13.4 10.5 16.6 9.4 15.2 14.8 19.0 12.3 21.9 23.4 13.6 11.6 11.6 13.0 11.8 12.7 18.4 20.9 13.6 18.4 12.0 11.5 9.5 12.2 10.6 16.4 10.6 8.5 12.8 12.6 13.6 10.0 16.4 12.3 14.7 17.1 4.8 12.9 16.8 12.8 5.0 8.1 23.0 9.4 4.7 4.3 4.8 8.5 5.6 6.9 7.5 12.1 12.4 6.0 9.4 10.4 9.1 9.5 4.6 9.6 4.0 7.8 9.8 8.7 10.2 9.6 15.2 6.4 6.2 8.1 5.8 7.1 8.2 4.4 11.5 9.7 10.8 10.6 19.0 11.0 4.0 8.6 13.8 6.8 9.6 4.8 5.3 11.1 2.9 7.1 3.4 16.9 9.4 5.1 5.6 7.5 24.5 11.3 11.5 7.9 9.8 11.0 8.4 8.3 6.9 7.3 7.5 2.9 9.6 7.1 9.4 12.9 9.4 11.5 3.5 8.8 4.3 5.0 3.6 2.6 6.3 4.3 3.2 3.8 23.0 4.7 9.4 8.1 4.0 4.8 13.5 21.8 18.9 24.4 19.0 12.3 11.6 13.0 18.4 12.3 UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908369-48929056 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007922: AB_1858551" "unprognostic (6.85e-2)" "unprognostic (5.72e-3)" "prognostic favourable (4.62e-4)" "unprognostic (9.11e-2)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (2.32e-2)" "unprognostic (5.26e-2)" "unprognostic (8.66e-2)" "unprognostic (9.17e-3)" "unprognostic (3.48e-2)" "prognostic unfavourable (1.05e-4)" "unprognostic (2.63e-2)" "unprognostic (2.11e-2)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" 27.1 40.6 29.2 27.7 37.0 22.2 28.8 34.4 50.2 33.7 28.9 59.9 45.1 26.6 36.2 49.5 37.2 36.0 28.0 28.7 30.5 29.2 32.1 25.6 29.2 30.9 46.6 28.0 32.5 29.5 36.6 28.0 35.0 39.7 32.9 32.5 28.4 33.3 43.2 24.1 35.9 30.5 39.1 32.7 36.6 29.4 22.4 43.4 29.4 39.8 22.2 44.2 28.8 32.2 12.8 10.1 11.0 14.5 7.4 13.1 8.6 24.8 30.9 11.6 11.0 29.5 28.7 15.9 27.3 33.5 32.7 31.6 38.5 21.6 20.3 39.2 33.4 16.2 14.5 25.5 41.8 67.1 15.8 18.3 20.4 23.9 34.2 13.0 19.8 24.4 28.3 26.6 34.6 23.9 13.4 26.5 35.1 39.8 14.0 12.9 10.8 27.0 11.3 29.6 11.5 25.6 24.5 12.0 18.2 18.5 10.0 18.6 27.6 10.3 28.1 49.0 23.7 16.0 22.2 20.2 19.2 12.0 24.0 9.5 21.2 6.5 11.0 8.1 13.1 14.5 10.7 9.4 11.4 13.0 8.0 12.8 11.1 12.0 11.0 7.4 13.0 10.1 11.5 8.6 29.2 37.0 34.4 50.2 30.5 29.2 46.6 28.0 39.7 43.4 UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" 19.3 19.4 20.3 23.1 25.0 17.8 20.2 30.0 25.1 21.7 19.9 14.3 19.8 14.1 21.0 22.1 19.8 18.5 17.2 24.0 22.2 20.8 20.2 24.6 19.7 23.1 19.1 19.5 23.0 17.2 26.1 24.6 20.1 20.9 20.6 17.9 13.3 19.3 21.5 70.2 18.4 18.8 21.2 19.9 18.8 16.9 26.4 16.4 36.4 25.0 26.6 19.5 19.9 26.6 15.6 11.9 11.6 14.8 21.1 16.0 5.7 19.3 10.9 27.6 16.4 16.1 19.2 13.6 29.8 18.7 21.1 19.2 25.3 9.7 34.7 22.6 22.2 17.9 34.9 21.0 25.8 17.9 11.7 28.8 18.4 14.9 24.2 34.7 21.3 22.6 19.8 19.9 25.5 16.5 29.0 24.8 33.1 10.5 28.7 10.1 17.9 15.9 29.5 41.2 15.3 19.1 30.4 28.3 21.4 24.1 26.2 34.2 21.4 19.6 21.2 37.0 30.6 17.7 21.7 28.4 33.5 46.8 21.2 18.9 19.2 8.6 8.7 11.6 13.3 7.6 15.2 12.0 14.0 15.9 11.9 15.6 16.0 14.2 2.0 21.1 14.8 11.1 10.1 5.7 20.3 25.0 30.0 25.1 22.2 20.8 19.1 19.5 20.9 16.4 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favourable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 14.5 19.3 17.2 12.9 21.2 9.2 15.3 19.7 27.8 14.4 17.3 23.3 14.0 14.6 17.4 16.2 20.1 19.3 13.9 28.6 14.6 11.6 19.8 16.4 15.5 13.1 18.6 13.9 18.4 20.3 25.5 15.1 16.8 15.8 17.5 21.2 20.7 15.7 17.4 34.0 21.6 16.3 18.6 15.2 17.0 17.3 24.5 18.3 18.2 21.1 17.6 15.9 19.5 19.6 15.9 14.5 22.4 16.7 14.3 18.2 11.4 10.4 16.6 13.0 9.4 22.2 17.9 11.4 13.8 15.9 16.8 11.3 17.3 10.8 6.5 10.3 22.6 13.5 13.2 17.7 16.3 14.3 9.3 12.5 10.8 15.6 14.3 10.1 10.5 20.3 16.6 16.3 19.6 18.1 13.6 6.2 19.1 16.4 6.9 14.8 13.3 20.0 11.5 12.3 12.8 14.4 18.9 12.1 22.4 16.1 22.0 10.8 22.4 10.8 16.5 20.9 6.0 10.6 9.8 13.9 11.5 11.5 20.8 8.5 17.3 22.4 15.3 14.3 15.9 16.7 15.7 15.9 15.3 11.2 14.5 12.9 12.9 17.1 19.5 14.3 13.6 13.5 18.2 11.4 17.2 21.2 19.7 27.8 14.6 11.6 18.6 13.9 15.8 18.3 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138913-157269372 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" Mitochondria "Nucleoplasm, Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favourable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 24.7 21.0 14.0 17.9 23.1 12.4 19.8 25.5 29.9 21.3 23.4 17.2 15.3 17.4 28.8 16.8 26.8 18.8 24.8 31.8 14.4 13.8 21.2 30.5 16.7 16.7 14.5 15.1 20.7 22.1 29.6 20.3 21.3 22.3 19.0 21.0 20.2 31.7 21.5 51.2 21.2 23.9 25.7 16.1 20.5 21.8 35.9 11.1 20.3 15.6 24.5 24.4 23.1 19.1 2.5 4.0 2.1 4.6 3.7 6.6 2.9 22.5 17.9 11.5 23.0 20.7 21.8 12.8 25.0 21.6 21.1 21.4 16.1 18.9 12.2 22.3 27.5 14.4 17.9 23.1 25.2 22.2 16.4 12.4 12.6 11.6 20.7 18.6 18.3 19.3 21.3 23.4 19.5 24.6 18.1 13.7 29.8 19.7 18.2 11.8 18.3 21.7 10.5 13.0 25.1 21.9 24.9 18.5 19.1 24.6 21.2 18.3 10.9 13.1 22.0 26.7 5.7 65.4 31.0 13.7 13.8 12.3 30.6 27.8 30.5 0.5 3.5 2.1 4.8 4.6 6.6 2.5 5.2 5.2 4.0 2.5 4.9 5.9 1.3 3.7 4.5 3.6 5.2 2.9 14.0 23.1 25.5 29.9 14.4 13.8 14.5 15.1 22.3 11.1 UBE3D "C6orf157, DKFZp434A1520, H10BH, UBE2CBP, YJR141W" ENSG00000118420 "Ubiquitin protein ligase E3D" Q7Z6J8 6 82892398-83065841 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027231 Uncertain Approved "Rods & Rings" "Rods & Rings" "HPA027231: AB_2256689" "unprognostic (1.91e-1)" "unprognostic (3.60e-2)" "unprognostic (5.05e-2)" "unprognostic (6.17e-3)" "unprognostic (2.91e-3)" "unprognostic (5.03e-2)" "unprognostic (2.39e-5)" "unprognostic (6.93e-2)" "unprognostic (2.08e-1)" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (4.26e-1)" "unprognostic (1.78e-1)" "unprognostic (1.58e-2)" "unprognostic (3.18e-1)" 4.6 9.0 6.3 6.2 9.5 3.0 8.7 13.1 10.6 6.7 5.5 6.0 4.9 7.5 6.9 5.0 6.7 14.0 5.1 5.4 6.1 9.1 7.9 4.9 4.1 7.6 7.4 7.2 8.0 10.1 8.9 11.0 4.2 5.9 4.1 6.8 6.4 6.5 5.6 8.8 4.1 4.2 8.7 5.8 8.2 6.3 3.7 7.7 4.5 10.0 5.2 7.8 8.6 6.0 6.6 3.1 0.3 2.7 1.3 8.2 3.2 2.7 3.8 3.7 3.4 3.1 5.0 3.0 3.0 3.6 3.8 6.5 5.4 1.5 12.5 4.6 1.8 2.9 7.3 3.6 6.0 5.3 16.5 7.2 2.1 5.9 4.2 6.2 3.6 3.9 5.1 4.1 5.0 4.9 10.3 5.7 3.2 3.1 3.8 7.8 4.7 6.1 5.7 8.5 5.0 7.1 3.7 6.7 4.2 1.7 4.3 2.6 2.7 4.5 1.5 1.6 4.4 3.5 7.2 6.3 12.7 4.2 2.8 11.4 3.4 0.0 1.0 0.3 4.7 2.7 6.1 6.6 5.2 3.7 3.1 4.4 5.6 8.2 0.0 1.3 1.2 2.3 5.2 3.2 6.3 9.5 13.1 10.6 6.1 9.1 7.4 7.2 5.9 7.7 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359585-118399211 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA055035: , HPA064010: " "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 19.3 18.5 17.7 20.5 30.1 16.6 19.7 49.4 36.6 19.0 18.5 33.0 16.1 20.3 23.2 21.2 21.2 19.8 17.0 20.3 17.7 18.8 20.3 29.5 18.4 22.2 25.7 25.7 24.2 26.7 31.1 24.2 18.6 35.5 21.5 23.1 21.2 20.3 17.2 32.5 25.6 23.7 19.9 25.5 24.0 25.5 21.8 27.5 22.1 22.1 15.1 22.6 21.6 20.4 5.7 11.0 14.6 13.2 7.1 9.0 5.2 9.1 8.9 11.4 11.4 19.8 18.4 11.4 13.6 14.2 10.1 12.4 24.5 22.6 19.3 26.3 17.0 20.3 16.1 12.8 16.8 10.8 7.5 31.6 8.0 12.6 17.1 17.8 24.3 18.5 9.3 20.6 20.3 16.8 17.9 18.2 14.5 17.3 15.2 17.8 10.6 11.4 9.7 16.6 19.7 11.1 21.4 10.4 10.8 19.6 17.0 6.0 22.7 8.2 17.2 15.0 9.9 12.8 11.2 5.4 6.5 18.4 8.3 20.7 15.3 14.6 10.9 10.5 9.0 12.0 6.9 5.7 6.9 6.4 11.0 4.3 7.4 6.6 11.0 7.1 13.2 6.5 7.7 5.2 17.7 30.1 49.4 36.6 17.7 18.8 25.7 25.7 35.5 27.5 UBE4B "E4, KIAA0684, UBOX3, UFD2" ENSG00000130939 "Ubiquitination factor E4B" O95155 1 10032832-10181239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019219 Approved "HPA019219: AB_1858554" "unprognostic (5.32e-2)" "unprognostic (1.56e-1)" "unprognostic (3.74e-2)" "unprognostic (5.46e-2)" "unprognostic (7.19e-2)" "unprognostic (4.39e-2)" "prognostic unfavourable (3.69e-5)" "unprognostic (2.53e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-1)" "unprognostic (4.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-3)" "unprognostic (2.99e-1)" "unprognostic (3.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" 11.8 18.6 16.4 11.5 20.2 16.5 12.7 27.1 24.2 17.5 19.3 26.5 12.6 15.1 16.7 12.8 20.4 14.1 11.3 22.5 18.9 17.3 13.0 13.9 10.5 11.3 18.5 15.0 22.8 20.4 24.3 15.3 18.3 23.6 14.5 12.8 18.2 12.0 12.7 43.5 24.3 14.5 16.6 16.3 13.0 15.1 8.6 21.4 15.7 19.7 11.2 13.6 16.8 12.0 6.0 6.7 9.4 7.9 2.9 9.8 5.3 21.6 13.9 17.1 18.8 22.7 30.0 13.5 14.3 18.1 14.0 14.4 15.0 25.4 18.7 17.4 25.4 16.0 21.4 16.5 16.7 19.1 12.0 20.1 24.3 17.6 17.2 21.0 14.3 24.7 15.0 18.9 16.1 20.6 34.5 24.9 13.0 11.3 13.5 10.3 22.8 11.5 13.3 17.0 20.1 14.2 9.9 20.9 16.1 22.5 16.1 29.7 12.3 15.5 17.8 12.6 19.4 15.5 11.6 11.4 15.4 21.6 18.5 24.4 15.9 4.2 7.9 3.6 5.3 6.0 8.8 6.0 8.8 8.5 6.7 5.6 8.0 6.5 9.4 2.9 4.4 3.2 9.8 5.3 16.4 20.2 27.1 24.2 18.9 17.3 18.5 15.0 23.6 21.4 UBOX5 "KIAA0860, RNF37, Ubce7ip5, UIP5" ENSG00000185019 "U-box domain containing 5" O94941 20 3107573-3160196 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028871 Approved Approved Nucleoplasm Nucleoplasm "HPA028871: AB_10603140" "unprognostic (4.11e-2)" "unprognostic (2.01e-2)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (2.18e-1)" "prognostic favourable (4.52e-5)" "unprognostic (2.58e-2)" "unprognostic (1.02e-1)" "unprognostic (3.11e-2)" "unprognostic (1.61e-1)" "prognostic favourable (1.80e-5)" "unprognostic (4.02e-2)" "unprognostic (9.71e-3)" "unprognostic (3.33e-1)" "unprognostic (5.58e-2)" "unprognostic (1.07e-2)" "unprognostic (1.61e-2)" 10.1 9.9 9.6 10.0 13.0 17.7 15.4 14.9 16.3 11.6 12.7 12.3 9.0 8.6 14.1 8.8 11.2 13.9 8.8 10.8 10.0 9.1 13.7 12.2 10.1 19.6 10.0 10.2 15.2 17.8 12.8 11.6 11.1 11.9 11.8 8.8 9.5 13.2 13.6 34.1 16.3 10.7 12.2 7.9 10.4 10.8 15.1 9.3 14.9 10.4 11.1 11.5 12.8 9.7 8.7 7.0 11.4 7.0 7.5 8.4 5.5 6.2 6.4 5.1 3.3 6.7 3.7 2.7 5.3 4.8 6.4 6.4 6.0 5.4 4.7 2.0 4.4 8.7 3.4 7.9 3.9 1.4 2.9 8.2 1.9 5.5 5.4 3.4 3.3 4.8 5.9 5.2 6.5 4.1 6.7 4.7 3.7 4.2 7.0 5.2 4.0 3.9 4.7 6.4 3.4 4.0 6.4 6.3 6.0 3.3 19.6 4.1 8.4 2.6 4.6 4.3 2.8 4.7 4.3 6.2 9.1 4.2 2.4 3.6 3.1 11.1 7.0 11.4 7.1 7.0 7.3 8.7 8.0 5.8 7.0 6.8 8.4 8.1 11.4 7.5 5.9 5.6 7.6 5.5 9.6 13.0 14.9 16.3 10.0 9.1 10.0 10.2 11.9 9.3 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038838 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA038838: AB_10673120" "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 16.7 13.2 13.7 18.3 16.7 28.4 18.8 21.8 18.1 18.2 16.2 14.8 10.5 11.3 21.0 12.9 10.8 15.9 14.2 19.7 10.0 15.4 14.4 10.6 16.6 14.9 11.8 10.5 16.3 16.4 26.3 25.6 16.2 18.9 15.3 12.9 12.5 11.8 16.8 23.6 11.0 14.4 18.2 12.1 14.7 13.8 13.7 14.7 23.2 18.8 9.7 14.3 17.3 19.7 4.6 5.0 5.5 4.2 6.2 7.2 1.8 4.9 7.2 8.3 6.7 13.2 10.2 7.9 12.1 13.4 10.7 13.9 9.1 3.9 5.8 7.2 12.4 8.6 11.9 10.6 12.8 11.9 5.8 22.9 14.4 4.4 9.2 16.1 11.0 11.0 6.0 13.1 10.7 12.0 13.0 8.8 13.3 2.8 8.7 4.8 4.7 7.4 11.4 11.4 5.0 10.8 11.7 8.4 7.5 15.9 8.4 5.6 8.1 8.4 16.5 13.2 8.2 11.7 12.2 10.4 17.6 16.7 9.0 10.2 11.9 4.4 3.0 5.2 5.7 4.2 6.5 4.1 5.9 6.9 2.9 4.6 5.9 7.2 5.5 6.2 3.4 5.0 4.1 1.8 13.7 16.7 21.8 18.1 10.0 15.4 11.8 10.5 18.9 14.7 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564062-42693504 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 25.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favourable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 19.8 18.8 14.4 21.8 16.7 22.1 18.6 26.6 20.4 17.2 19.3 17.8 17.8 20.1 29.5 16.8 16.2 15.6 16.2 16.8 13.8 13.2 17.8 24.0 19.3 18.0 16.7 12.9 20.8 24.6 28.0 26.3 16.3 17.2 16.5 20.1 15.8 18.3 15.6 33.5 18.0 24.6 19.9 15.9 21.3 18.2 9.2 17.2 26.1 20.1 14.9 17.7 18.9 29.8 3.6 3.5 25.2 5.7 3.9 4.4 1.9 15.7 8.0 9.3 14.6 19.2 18.5 12.6 12.2 13.2 10.8 11.3 11.5 6.5 10.9 9.7 13.1 16.0 13.4 10.4 13.8 14.6 9.4 17.2 11.9 14.9 15.6 16.6 11.9 13.0 11.4 10.7 11.8 12.2 20.1 13.8 10.4 12.8 13.0 14.7 8.5 7.8 11.6 13.9 16.2 12.4 13.8 11.1 8.8 12.3 11.9 11.9 11.6 16.1 17.6 9.9 7.7 12.0 8.8 12.8 11.3 16.8 5.2 12.5 6.0 10.4 4.6 9.2 4.4 4.8 3.7 3.4 2.9 3.4 3.5 3.6 3.0 3.3 25.2 3.9 5.7 2.6 3.3 1.9 14.4 16.7 26.6 20.4 13.8 13.2 16.7 12.9 17.2 17.2 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3 (putative)" Q6ZT12 2 169827458-170084131 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 11.9 15.5 10.9 6.1 18.3 5.4 9.6 15.5 18.9 9.9 10.0 9.8 9.1 6.7 11.5 7.1 10.7 8.1 7.8 23.1 10.3 7.2 12.9 16.9 9.2 5.6 11.9 14.0 8.9 9.8 20.9 14.9 7.2 14.7 11.2 7.3 8.0 11.1 9.2 76.3 11.5 8.4 9.6 10.2 6.9 9.2 7.9 11.4 6.3 14.9 10.9 6.0 12.8 8.7 2.0 2.8 1.9 2.1 2.4 4.3 1.2 8.8 7.5 8.0 10.6 16.0 12.7 6.8 16.0 9.3 9.3 7.5 11.5 5.6 10.0 13.9 12.4 11.7 9.5 8.1 11.6 10.4 8.2 36.6 8.0 12.2 8.0 12.1 11.9 7.6 7.6 12.1 8.1 9.1 19.0 10.9 15.7 8.3 7.8 5.9 6.3 6.3 7.5 13.2 10.6 6.7 12.5 15.8 8.6 11.2 10.4 6.5 6.8 6.8 11.5 14.0 5.7 10.9 10.0 8.9 6.9 9.2 11.5 7.1 7.7 0.0 2.1 1.7 3.2 1.8 4.2 2.0 1.9 2.7 2.8 1.2 3.3 4.3 1.9 2.4 1.6 2.4 3.1 1.2 10.9 18.3 15.5 18.6 10.3 7.2 11.9 14.0 14.7 11.4 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074506-19210276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 24.4 25.4 22.4 29.0 25.4 58.3 23.7 28.5 32.5 22.4 28.5 26.3 31.5 18.2 34.0 32.5 22.7 20.3 27.3 20.5 23.3 15.9 25.5 29.7 31.2 20.3 21.0 20.9 35.5 21.0 40.9 31.4 28.4 25.0 30.7 20.5 30.6 24.7 27.1 55.9 69.0 25.5 39.3 20.2 26.5 30.2 41.1 21.6 37.7 26.1 17.3 25.9 43.4 29.0 4.6 9.1 18.3 18.5 2.7 3.4 4.6 22.9 23.2 21.0 15.5 39.3 20.3 18.2 17.9 18.9 19.5 17.8 37.0 19.8 13.9 16.8 23.6 15.7 16.4 17.8 18.3 11.5 14.5 31.7 22.4 24.1 27.7 19.4 21.1 18.1 22.9 39.7 38.3 21.3 21.6 12.9 18.5 16.4 9.1 23.7 17.0 13.1 12.8 16.4 11.6 17.6 13.5 14.9 14.8 21.2 12.2 15.2 8.4 15.3 33.0 22.9 14.3 27.1 20.0 15.3 9.2 16.1 15.7 30.0 19.4 18.3 18.5 2.9 3.4 3.8 2.9 4.6 3.0 1.9 9.1 2.9 2.7 2.5 9.8 2.7 1.3 4.3 2.1 4.6 22.4 25.4 28.5 32.5 23.3 15.9 21.0 20.9 25.0 21.6 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102253012-102412841 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA053688: " "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 27.0 16.7 27.1 29.5 31.7 30.3 29.2 40.8 32.8 24.9 25.0 19.1 21.1 14.4 26.8 24.0 23.8 22.0 17.6 22.7 25.5 15.3 17.9 17.0 24.2 29.6 21.9 20.6 29.7 22.2 32.4 25.5 25.0 23.6 20.2 17.1 19.7 22.9 21.8 39.9 29.7 22.4 29.3 17.5 21.9 21.1 39.7 28.3 37.9 20.3 15.9 27.0 27.5 28.6 5.0 4.0 6.3 5.5 2.4 7.1 2.1 23.2 10.4 20.2 10.3 19.9 20.3 18.6 17.6 15.6 13.8 12.1 10.4 15.7 46.4 15.2 16.5 14.2 17.2 15.3 19.4 20.0 8.4 38.7 14.2 18.7 17.7 12.0 21.4 23.2 15.3 14.2 24.8 16.5 18.6 26.4 13.5 21.0 30.5 14.4 15.2 11.8 17.8 11.9 22.0 12.6 22.9 14.9 12.4 12.3 12.0 12.2 19.2 12.8 16.5 14.7 17.2 13.2 12.2 14.1 13.6 47.7 14.6 18.8 11.9 3.1 3.4 5.0 5.6 3.4 5.6 5.0 6.0 5.9 4.0 3.9 4.8 7.1 6.3 2.4 5.5 3.6 7.1 2.1 27.1 31.7 40.8 32.8 25.5 15.3 21.9 20.6 23.6 28.3 UBR7 C14orf130 ENSG00000012963 "Ubiquitin protein ligase E3 component n-recognin 7 (putative)" Q8N806 14 93207056-93229215 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000861 Approved Approved Nucleoplasm Nucleoplasm "HPA000861: AB_1078321" "unprognostic (9.60e-2)" "unprognostic (5.12e-3)" "unprognostic (1.11e-1)" "unprognostic (9.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "prognostic unfavourable (8.12e-5)" "unprognostic (1.14e-1)" "unprognostic (9.83e-2)" "unprognostic (1.04e-2)" "unprognostic (4.30e-2)" "unprognostic (5.94e-2)" "prognostic favourable (9.76e-5)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" 14.1 12.3 16.4 12.5 22.9 17.0 17.5 20.0 25.8 17.1 15.7 17.7 11.3 11.1 14.9 13.4 14.8 13.7 11.9 19.0 14.2 12.8 15.3 13.2 11.9 18.0 14.0 17.1 17.0 20.4 28.2 11.5 11.4 13.3 13.9 17.1 13.6 13.7 14.9 19.9 15.2 12.7 14.1 16.9 13.8 14.1 21.1 14.3 31.9 15.4 12.9 23.3 13.4 13.3 18.1 10.7 15.8 9.5 11.5 16.5 8.2 6.4 8.7 13.3 11.1 6.3 6.7 4.7 13.7 9.7 15.2 11.6 6.3 7.4 15.4 11.5 6.9 7.8 14.3 7.7 15.7 11.9 7.7 11.1 9.3 6.0 2.9 16.2 12.5 4.0 5.4 8.4 5.3 8.5 10.3 15.5 14.5 18.9 26.3 8.9 6.1 15.7 20.3 23.9 8.4 5.1 10.6 16.8 12.0 9.8 8.2 4.0 14.9 11.2 6.5 11.2 6.1 9.6 14.1 17.9 27.4 15.8 9.8 12.6 9.5 15.8 7.3 11.8 12.7 9.1 13.3 18.1 11.4 11.7 7.8 14.8 10.0 10.6 11.5 11.5 9.5 10.7 16.5 8.2 16.4 22.9 20.0 25.8 14.2 12.8 14.0 17.1 13.3 14.3 UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531268 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050969 Approved Approved Nucleoplasm Nucleoplasm "HPA050969: " "unprognostic (2.20e-1)" "prognostic favourable (3.19e-4)" "unprognostic (1.16e-2)" "unprognostic (1.74e-3)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.54e-1)" "prognostic favourable (2.21e-7)" "unprognostic (5.11e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" 13.2 15.9 21.7 13.7 22.5 13.7 15.6 29.9 23.2 15.0 15.6 17.3 20.8 11.4 12.2 19.3 14.5 17.6 16.5 21.0 19.6 18.4 18.3 26.7 12.7 12.9 20.4 19.1 21.3 24.0 17.6 14.4 16.4 14.8 14.9 9.2 17.6 24.1 18.3 30.0 12.0 12.2 14.8 19.9 12.1 13.4 15.7 15.6 12.5 18.5 10.8 11.5 13.6 9.4 7.9 6.6 9.4 7.8 6.8 13.5 6.1 6.9 15.4 17.9 22.9 12.7 9.1 15.2 11.3 16.8 19.6 15.0 15.3 6.4 7.6 6.8 13.5 13.6 16.6 14.5 8.5 13.9 15.5 7.1 23.2 9.6 18.2 11.6 10.5 10.2 13.6 15.8 11.5 12.0 8.9 5.8 14.4 27.7 15.8 5.9 21.2 15.4 15.2 27.7 12.7 12.6 6.6 24.2 15.2 16.3 12.5 17.6 24.4 6.9 8.8 21.8 11.1 13.5 11.0 12.0 15.3 9.6 10.8 8.1 15.1 2.3 6.2 9.4 8.5 7.8 11.3 7.9 10.1 7.6 5.7 7.9 13.5 6.8 4.1 6.8 2.7 6.6 12.3 6.1 21.7 22.5 29.9 23.2 19.6 18.4 20.4 19.1 14.8 15.6 UCK2 UMPK ENSG00000143179 "Uridine-cytidine kinase 2" Q9BZX2 1 165827531-165911618 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 65.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057128 Approved Nucleoplasm Nucleoplasm "HPA057128: " "unprognostic (5.37e-2)" "unprognostic (1.75e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" "unprognostic (4.54e-2)" "unprognostic (6.83e-3)" "prognostic unfavourable (9.22e-8)" "prognostic unfavourable (4.98e-4)" "prognostic unfavourable (6.70e-4)" "unprognostic (3.04e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "prognostic unfavourable (5.12e-13)" "unprognostic (2.49e-3)" "unprognostic (1.14e-1)" "unprognostic (2.01e-3)" "unprognostic (1.83e-1)" 12.5 7.1 6.5 11.1 8.6 11.6 17.5 16.9 9.6 9.3 18.4 8.9 11.0 15.3 10.1 15.3 20.5 8.8 9.0 9.6 6.4 6.6 6.6 14.6 11.1 10.3 10.5 6.6 7.5 17.6 7.9 9.4 65.8 11.2 8.1 19.9 5.0 16.1 9.9 20.9 15.0 24.8 10.0 8.2 7.7 13.2 7.2 7.9 13.1 6.4 12.4 12.3 9.0 11.1 3.4 14.7 0.8 5.6 3.4 3.9 2.0 25.2 26.3 14.2 12.7 7.3 12.2 23.1 27.9 20.6 29.8 34.0 25.0 27.8 12.5 19.9 17.3 20.8 26.6 32.8 26.7 22.9 22.5 14.5 22.6 25.6 18.2 28.3 11.1 11.5 16.9 56.2 35.1 19.6 38.3 18.0 26.7 18.3 25.1 18.2 38.9 25.5 11.5 15.6 42.5 13.8 16.5 21.4 25.3 19.9 39.4 19.3 24.3 27.0 20.4 16.7 23.3 18.9 29.5 24.2 36.0 46.3 14.4 18.8 12.7 0.8 5.6 0.1 1.8 3.7 3.9 3.4 1.7 2.4 14.7 3.4 0.0 1.4 0.2 3.4 3.2 14.0 2.2 2.0 6.5 8.6 16.9 9.6 6.4 6.6 10.5 6.6 11.2 7.9 UCKL1 "FLJ20517, URKL1" ENSG00000198276 "Uridine-cytidine kinase 1 like 1" Q9NWZ5 20 63939829-63956415 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004722, HPA004769" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA004722: AB_1080455, HPA004769: AB_1080453" "unprognostic (1.03e-1)" "unprognostic (2.77e-2)" "unprognostic (2.64e-1)" "unprognostic (8.34e-2)" "unprognostic (7.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "prognostic favourable (4.42e-4)" "unprognostic (5.87e-2)" "unprognostic (3.18e-2)" "unprognostic (9.11e-2)" "unprognostic (2.81e-1)" "unprognostic (3.01e-1)" "unprognostic (5.26e-3)" 17.4 18.1 16.5 16.0 18.3 21.1 19.8 50.4 20.7 18.5 21.9 21.6 17.3 32.0 18.0 17.7 19.7 17.9 12.0 21.0 17.1 9.4 21.3 20.6 15.6 18.3 20.3 11.5 31.7 22.6 14.1 22.1 17.5 15.7 19.4 9.1 31.0 28.9 24.4 52.3 27.9 29.8 18.1 11.8 26.7 20.1 11.5 19.7 16.7 24.1 33.1 20.1 16.2 21.2 22.2 8.9 6.3 14.0 5.3 14.8 7.9 11.3 12.1 10.4 13.9 7.7 6.6 16.8 9.1 6.3 19.0 9.5 28.9 8.9 11.5 15.5 5.9 18.7 8.1 12.6 3.8 4.8 13.6 8.7 24.2 42.2 8.5 14.8 16.7 9.2 11.3 7.6 6.3 8.7 12.3 12.3 5.9 14.6 17.4 25.9 7.7 28.4 17.8 7.8 19.8 7.8 16.5 24.8 14.5 13.2 13.0 14.0 13.6 13.5 9.6 20.2 7.6 13.1 11.8 12.9 6.9 5.3 10.3 10.7 7.6 4.2 7.7 6.3 13.2 12.9 14.8 22.2 12.8 11.2 8.9 12.7 7.5 9.0 1.2 5.3 14.0 5.1 13.5 7.9 16.5 18.3 50.4 20.7 17.1 9.4 20.3 11.5 15.7 19.7 UGCG GCS ENSG00000148154 "UDP-glucose ceramide glucosyltransferase" Q16739 9 111896766-111935369 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "LHCN-M2: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 19 "plasmacytoid DC: 39.7" "Lineage enriched" "Detected in many" 19 "dendritic cells: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024124 Approved "HPA024124: AB_1858595" "unprognostic (1.22e-2)" "prognostic favourable (6.62e-4)" "unprognostic (5.39e-2)" "prognostic favourable (4.44e-5)" "unprognostic (1.53e-2)" "unprognostic (9.70e-2)" "unprognostic (3.20e-2)" "unprognostic (2.04e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (3.22e-1)" "unprognostic (9.84e-3)" "unprognostic (2.24e-2)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (3.77e-2)" 33.7 37.7 5.9 21.4 7.8 55.2 20.5 9.5 11.2 14.6 19.6 5.0 3.3 13.3 10.6 8.6 34.0 11.1 24.5 17.5 8.6 9.0 23.8 18.4 28.1 35.4 7.1 5.8 15.9 11.4 3.5 11.9 15.3 6.8 12.4 10.5 11.9 10.8 5.4 14.0 21.7 25.5 12.4 12.9 33.1 26.1 11.7 6.2 17.9 8.5 16.9 27.7 34.2 25.9 2.0 39.7 0.4 0.3 0.5 1.2 0.5 24.1 2.6 4.2 2.8 9.2 11.1 2.2 15.1 16.0 17.8 24.1 5.1 18.6 5.7 12.0 10.0 12.4 4.9 6.5 19.1 2.3 2.8 2.3 3.9 2.5 6.6 2.5 3.7 11.0 5.1 16.9 24.4 5.4 12.6 11.1 52.4 4.1 2.7 2.8 4.8 2.7 3.2 30.2 1.8 40.9 9.2 2.0 3.2 6.7 5.7 16.6 30.5 2.6 25.5 8.2 4.2 22.9 10.8 2.1 7.6 2.6 10.1 1.6 11.1 0.0 0.1 0.0 0.4 0.2 0.7 1.6 0.8 0.6 0.6 2.0 0.7 0.7 0.4 0.5 0.3 39.7 1.2 0.5 5.9 7.8 9.5 11.2 8.6 9.0 7.1 5.8 6.8 6.2 UGP2 "UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840940-63891562 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 93.6;T-reg: 29.9" "Group enriched" "Detected in all" 5 "granulocytes: 93.6;T-cells: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria 12000000 "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favourable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 58.2 14.7 23.3 13.6 22.5 7.8 25.2 12.4 30.4 13.3 38.2 6.7 7.4 12.3 15.5 12.5 19.8 12.7 12.2 46.3 18.8 13.2 33.0 185.5 12.7 15.2 17.3 18.3 12.0 13.4 17.1 22.9 31.0 19.3 11.0 33.1 5.7 18.5 12.9 104.1 11.0 17.2 16.8 8.6 9.9 13.0 8.1 10.5 31.0 17.4 75.5 12.7 19.7 19.5 6.4 5.9 93.6 7.8 12.7 29.9 11.0 27.3 14.4 13.8 9.3 47.2 61.2 58.0 35.4 29.0 19.1 22.8 36.9 23.3 28.7 10.7 38.0 12.0 16.7 22.2 31.0 19.2 7.1 18.2 10.2 25.2 22.5 16.0 16.1 40.1 40.7 17.9 18.5 26.5 9.1 11.7 79.6 10.8 21.7 15.1 33.1 10.1 17.8 27.4 16.6 33.8 16.0 7.3 6.0 28.3 36.4 13.4 10.4 11.4 36.1 20.0 31.6 29.7 18.6 20.9 9.4 36.4 24.0 25.1 61.0 93.6 7.0 9.7 9.9 7.8 10.3 6.4 11.4 10.3 5.9 6.2 12.6 11.2 9.0 12.7 7.6 5.5 29.9 11.0 23.3 22.5 12.4 30.4 18.8 13.2 17.3 18.3 19.3 10.5 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760248-233773299 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 48.6;liver: 120.3" "Cell line enhanced" "Detected in some" "CACO-2: 4.2;HaCaT: 11.0;PC-3: 5.0;RT4: 26.1" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 4.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.2 35.6 0.1 0.1 48.6 0.1 0.1 4.3 0.0 0.3 0.1 0.1 0.0 4.5 120.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.4 0.1 0.7 0.1 0.1 0.9 48.2 0.5 0.1 0.1 1.3 0.2 0.1 0.1 0.2 0.1 0.1 5.2 0.8 1.0 0.4 4.7 0.4 1.1 0.5 0.2 0.2 0.8 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.0 0.0 4.2 0.3 0.1 2.0 0.0 11.0 0.0 0.2 0.0 0.2 0.1 0.1 0.4 1.1 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.2 0.4 5.0 0.1 0.1 0.4 0.0 26.1 0.2 0.3 2.0 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.6 0.3 0.2 2.1 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.3 0.1 1.0 0.4 0.5 4.7 1.1 0.4 0.4 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 9.4;gallbladder: 8.4;intestine: 31.1;stomach 1: 12.4" "Cell line enriched" "Detected in single" 142 "RT4: 106.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavourable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.3 0.0 0.3 2.6 0.3 0.0 0.3 0.3 0.3 0.3 19.2 0.3 0.3 31.1 0.3 0.3 9.4 0.1 8.4 0.3 0.3 0.0 0.3 1.4 0.6 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 14.3 0.3 0.9 0.3 0.3 0.3 20.2 0.5 0.3 0.3 12.4 1.0 0.3 0.3 0.3 0.3 1.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 40.6" "Cell line enriched" "Detected in some" 9 "HaCaT: 16.4" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718778-233773299 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "liver: 99.4" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;HL-60: 1.3;RH-30: 2.2" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A5 UGT1E ENSG00000240224 "UDP glucuronosyltransferase family 1 member A5" P35504 2 233712992-233773299 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 3.7;intestine: 13.9" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;RT4: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.18e-3)" "unprognostic (1.36e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 11.2 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 9.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 111.7;liver: 50.1;urinary bladder: 32.7" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;EFO-21: 20.8;HaCaT: 74.4;RT4: 37.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009819, HPA054065" Enhanced "CAB009819: AB_2241481, HPA054065: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.8 0.5 0.2 0.5 2.0 0.3 0.9 13.0 0.0 1.1 0.1 0.1 0.0 111.7 50.1 1.9 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.3 0.1 3.3 0.4 0.1 1.3 1.2 0.1 3.8 1.2 2.3 0.1 0.1 8.1 0.2 0.1 0.5 0.2 5.6 8.7 32.7 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.4 0.0 20.8 0.0 74.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 37.6 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "esophagus: 54.4;lymphoid tissue: 40.2;tongue: 23.6" "Cell line enriched" "Detected in some" 14 "SiHa: 49.4" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.0 0.1 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 40.2 0.2 2.8 0.2 0.1 1.6 0.2 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 49.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.6 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 13.0;urinary bladder: 15.7" "Cell line enriched" "Detected in single" 58 "RT4: 51.2" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.3 0.0 0.0 0.0 0.0 0.0 3.3 5.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671853-233773300 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 169.8" "Group enriched" "Detected in some" 20 "A549: 4.8;RT4: 3.9" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavourable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.8 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" Q9Y4X1 4 69588417-69653249 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 10.6;liver: 14.5;pituitary gland: 21.2" "Cell line enhanced" "Detected in some" "ASC diff: 3.1;HUVEC TERT2: 1.9;U-266/70: 3.5" "Cancer enhanced" "Detected in some" "liver cancer: 0.7" "Region enriched" "Detected in single" 17 "pons and medulla: 1.7" "Cell type enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "HPA017261, HPA045108" Uncertain "HPA017261: AB_10963582, HPA045108: " "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 14.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.7 0.0 0.0 1.5 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 2.0 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.2 1.7 0.5 0.4 0.2 0.2 0.1 0.1 0.4 0.2 0.1 0.3 0.2 0.1 2.0 0.9 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 UGT2A2 ENSG00000271271 "UDP glucuronosyltransferase family 2 member A2" Q9Y4X1 4 69589309-69639642 "Enzymes, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix, uterine: 1.6;kidney: 2.6;liver: 5.4;pituitary gland: 3.8;skin 1: 1.8" "Cell line enhanced" "Detected in single" "U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.4 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951791 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 150.5;kidney: 43.2" "Cell line enriched" "Detected in some" 9 "Hep G2: 20.5" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "eosinophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" HPA045108 Supported "HPA045108: " "prognostic favourable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favourable (6.07e-7)" "unprognostic (2.10e-2)" 0.1 0.1 0.1 4.3 0.1 0.0 0.7 0.1 0.1 0.1 63.8 0.1 0.1 31.9 0.1 1.7 0.1 0.1 14.6 0.3 0.1 0.1 43.2 9.6 0.1 0.1 0.1 0.1 0.1 12.0 0.0 0.1 0.1 0.1 0.1 8.6 0.1 0.1 0.1 0.1 0.1 150.5 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815993-68831196 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 277 "liver: 120.4" "Cell line enriched" "Detected in single" 39 "Hep G2: 15.8" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 120.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214731 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "breast: 77.4" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;HL-60: 3.0;NB-4: 2.4;RPTEC TERT1: 3.6;U-2197: 1.4" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "basophil: 6.8;eosinophil: 5.6" "Lineage enriched" "Detected in single" 68 "granulocytes: 6.8" HPA045108 Uncertain "HPA045108: " "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 77.4 0.1 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.0 3.3 0.1 0.1 0.0 1.2 7.3 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 7.0 0.1 0.1 1.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 3.6 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.6 0.0 0.0 6.8 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646630-68670628 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 22.4;intestine: 50.7;liver: 65.4" "Cell line enhanced" "Detected in some" "A549: 3.2;HL-60: 2.1;RH-30: 1.2;RPMI-8226: 1.1" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.7" "Lineage enhanced" "Detected in single" "B-cells: 2.7" HPA045108 Approved "HPA045108: " "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favourable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favourable (4.50e-4)" 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 48.0 0.1 0.1 5.4 0.1 0.1 0.2 0.0 22.4 0.1 0.1 0.0 0.1 65.4 0.1 0.1 0.1 0.1 0.1 5.3 0.0 0.1 0.1 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.0 50.7 0.1 0.1 0.1 5.7 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 1.1 0.0 0.2 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.4 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 68.1;liver: 21.6" "Group enriched" "Detected in some" 7 "BEWO: 3.1;NB-4: 3.5;RPMI-8226: 5.1;SH-SY5Y: 2.3;U-2197: 2.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "memory B-cell: 3.3;naive B-cell: 11.9" "Lineage enriched" "Detected in single" 59 "B-cells: 11.9" HPA045108 Supported "HPA045108: " "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.4 0.1 0.4 4.7 0.4 0.0 0.4 0.4 0.4 0.4 55.6 0.4 0.4 54.1 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.1 0.4 21.6 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 20.7 0.4 0.4 0.4 0.4 0.1 68.1 1.1 0.4 0.4 0.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 11.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.4 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280499-69295050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 71.7;salivary gland: 25.6" "Group enriched" "Detected in some" 10 "Daudi: 6.9;NB-4: 6.3" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 4.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 4.0" HPA045108 Uncertain "Intracellular and membrane" "HPA045108: " "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 71.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 25.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.2 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 105 "liver: 175.1" "Cell line enriched" "Detected in some" 9 "RH-30: 10.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" "CAB033260: AB_2241496, HPA045108: " "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 175.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 125.4;liver: 156.0" "Group enriched" "Detected in some" 5 "EFO-21: 20.5;RPTEC TERT1: 81.6" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favourable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favourable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favourable (5.38e-4)" 0.1 0.1 0.1 0.2 0.1 0.0 0.4 0.1 0.1 3.1 7.9 0.1 2.5 6.4 0.6 4.7 0.1 4.7 1.5 0.1 0.1 0.1 125.4 156.0 0.2 0.1 0.1 0.1 0.6 14.7 0.0 0.1 0.2 0.1 0.3 0.4 0.2 1.0 2.7 0.3 0.2 27.7 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 81.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951010-36001028 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 44.0;liver: 47.7" "Cell line enriched" "Detected in single" 42 "RH-30: 24.7" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA047697: , HPA056290: " "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 5.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 44.0 47.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 3.2 0.1 6.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.2 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035017-36071358 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 37.0;skin 1: 14.4;testis: 13.2" "Cell line enhanced" "Detected in some" "HDLM-2: 5.2;MOLT-4: 9.3;REH: 21.8;T-47d: 5.7;THP-1: 12.9" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Region enhanced" "Detected in single" "pons and medulla: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: " "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.1 1.1 0.1 0.0 0.2 6.4 1.6 0.1 0.6 0.1 0.1 0.5 0.4 0.0 0.1 0.8 0.1 0.1 0.2 0.2 0.1 0.6 5.6 0.8 0.1 0.0 0.5 0.0 0.2 0.0 0.0 1.7 0.2 2.0 0.6 0.0 2.9 0.1 0.0 0.1 14.4 0.1 0.0 0.3 1.4 0.1 13.2 0.0 37.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.4 5.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 4.0 0.0 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.6 0.1 0.6 0.5 0.0 2.0 0.0 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598455-114678224 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.3;RH-30: 12.1;RPTEC TERT1: 25.0;SCLC-21H: 14.2;U-87 MG: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 7.3;naive B-cell: 10.6" "Lineage enriched" "Detected in single" 12 "B-cells: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria Mitochondria "HPA014405: AB_1858606, HPA065785: " "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favourable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.9 0.8 13.2 2.8 30.0 1.0 3.1 2.7 44.8 4.9 15.5 66.6 0.0 18.4 2.7 0.6 1.2 3.0 7.1 0.9 24.2 12.4 20.1 0.8 1.0 3.2 53.9 15.9 0.8 4.8 0.3 0.9 0.5 38.3 0.9 17.3 0.0 4.5 0.8 0.8 1.8 16.1 1.5 96.6 1.3 10.0 3.3 42.6 0.0 8.5 0.0 3.4 0.8 1.0 10.6 0.0 0.9 0.0 0.0 0.6 0.3 0.3 0.1 2.0 0.3 0.1 0.0 0.3 0.1 0.0 0.0 1.5 6.8 25.3 7.6 0.6 0.1 10.7 0.0 0.0 0.0 0.1 5.3 0.1 11.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 6.4 1.5 0.0 0.1 0.1 0.8 3.0 3.8 0.7 12.1 0.2 25.0 0.3 14.2 2.1 0.1 2.2 0.3 0.4 2.4 0.5 0.5 8.6 0.3 7.9 2.5 0.4 0.2 12.5 0.4 7.8 0.2 0.0 0.9 0.0 0.0 0.6 7.3 0.1 0.0 0.0 10.6 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.3 13.2 30.0 2.7 24.4 24.2 12.4 53.9 15.9 38.3 42.6 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529629 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071190 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA071190: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 21.6 22.0 23.5 18.9 26.2 30.1 23.5 10.8 30.5 14.3 16.3 17.2 30.8 16.3 11.5 12.9 16.0 12.9 12.1 11.4 27.0 31.8 27.9 32.4 16.9 24.3 30.6 20.3 12.1 11.8 25.0 12.5 16.5 33.4 14.7 17.4 14.1 15.9 22.9 30.6 11.5 21.8 9.6 20.5 21.3 16.8 10.4 14.1 23.0 17.1 11.7 24.1 16.1 12.8 5.7 4.3 4.5 9.2 5.9 8.5 4.0 20.8 9.8 5.1 12.5 14.7 11.6 11.6 27.7 15.1 22.7 16.3 6.3 13.1 17.1 24.2 20.6 12.1 9.8 15.2 36.6 23.4 7.1 16.9 12.2 5.7 11.3 24.6 19.8 11.9 16.2 22.3 21.4 13.0 14.7 23.8 38.9 8.8 13.0 6.5 6.8 13.3 8.4 22.9 14.2 15.1 21.6 9.3 8.6 24.4 22.7 17.8 19.6 27.6 20.2 26.0 14.7 17.9 38.5 24.7 34.2 20.2 21.6 12.1 23.4 4.5 3.3 3.7 8.2 8.6 8.5 5.4 6.2 6.8 3.6 5.7 6.3 7.1 2.0 5.9 9.2 4.3 4.9 4.0 23.5 26.2 10.8 30.5 27.0 31.8 30.6 20.3 33.4 14.1 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 75.6" "Cell line enhanced" "Detected in many" "MOLT-4: 62.6;REH: 142.1" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.2" "Group enriched" "Detected in many" 4 "dendritic cells: 8.2;T-cells: 4.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavourable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavourable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 8.2 3.7 16.5 0.7 0.3 4.2 0.3 1.5 1.6 0.0 2.1 0.3 0.2 2.0 0.0 1.0 0.9 1.2 0.1 0.1 0.3 10.0 4.3 0.7 0.3 0.6 0.0 0.0 1.0 1.4 0.0 1.4 0.0 0.0 0.0 0.3 1.9 2.2 0.8 0.7 2.2 1.9 3.1 4.0 75.6 0.0 4.0 6.6 1.1 0.0 0.4 8.2 1.5 0.4 0.9 4.2 0.9 15.6 11.3 17.2 12.2 0.5 2.0 2.7 12.7 6.1 13.3 12.9 13.5 7.9 8.9 3.1 5.6 7.8 11.8 6.9 9.4 14.4 13.4 7.7 10.6 14.4 0.2 18.9 11.7 0.9 0.5 7.2 1.8 3.9 11.0 10.3 7.9 12.2 62.6 11.6 7.7 12.3 142.1 38.3 6.5 3.6 11.5 12.7 10.1 10.0 5.5 1.7 9.9 18.1 4.9 14.1 11.5 18.2 15.3 4.4 4.5 26.2 8.1 18.4 17.9 0.6 0.4 0.2 1.1 0.1 0.1 0.3 1.5 1.9 2.2 0.4 0.4 1.5 1.5 0.9 0.3 8.2 4.2 0.9 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm Nucleoplasm "HPA026633: AB_1858610, HPA026697: AB_1858611" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 14.1 12.9 10.6 25.4 12.2 49.1 19.0 24.8 11.8 18.6 15.6 12.7 17.6 7.9 17.5 15.1 13.3 12.0 11.9 11.3 10.2 10.6 10.1 9.8 13.5 19.3 12.3 10.5 18.9 14.5 12.7 12.7 14.6 11.4 19.3 12.0 10.7 13.0 16.4 15.7 11.0 12.0 17.1 12.2 14.1 11.6 10.6 14.8 40.3 15.2 10.2 19.8 18.7 18.2 5.1 2.5 7.5 1.4 1.2 3.6 1.2 6.6 7.5 10.9 4.6 9.0 12.9 8.0 15.3 9.4 9.6 16.9 4.8 4.8 10.2 3.3 7.6 4.3 10.0 8.9 14.8 18.3 4.7 17.7 14.7 7.6 7.4 8.2 6.0 5.8 5.8 7.5 18.4 37.5 1.7 9.9 22.7 2.3 13.8 32.1 4.2 5.6 15.8 5.0 3.6 7.2 4.6 9.9 3.8 6.6 4.4 9.6 5.5 16.6 31.7 10.3 3.8 4.3 12.8 2.6 7.9 11.9 5.0 7.2 4.1 7.5 1.1 4.3 2.3 0.9 1.7 3.5 3.6 1.8 0.7 5.1 2.3 3.0 1.3 1.2 1.4 2.5 3.5 1.2 10.6 12.2 24.8 11.8 10.2 10.6 12.3 10.5 11.4 14.8 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894651-131923167 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9;plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol Cytosol "HPA063990: " "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 10.9 18.6 14.6 9.2 49.6 33.2 8.9 24.0 24.4 14.4 11.8 6.9 13.3 11.7 16.5 10.7 9.8 10.6 16.2 17.4 11.5 8.3 9.0 15.8 9.0 8.3 7.9 12.0 18.2 59.6 13.8 23.8 17.2 11.6 13.4 4.0 13.9 18.1 13.4 33.4 24.3 11.5 10.2 5.4 16.5 11.4 11.4 11.4 13.8 10.7 9.6 6.5 12.1 10.9 0.6 6.4 6.9 1.7 0.2 0.8 0.6 5.1 16.6 7.7 9.6 3.5 2.8 10.5 8.2 5.9 3.5 2.8 3.6 5.3 1.4 8.6 5.7 5.1 1.7 3.2 1.0 5.5 10.0 3.4 13.6 4.8 6.5 2.5 7.6 5.2 9.0 3.9 1.6 4.3 4.5 4.1 2.3 11.7 15.3 14.5 8.5 15.9 11.6 2.8 6.8 2.0 6.4 19.6 10.8 8.7 9.0 4.5 13.7 16.8 8.2 8.4 5.0 14.6 3.7 18.3 6.6 1.8 14.2 4.3 9.6 0.2 1.7 2.3 0.8 0.7 0.2 0.1 0.7 0.7 0.3 0.6 0.5 0.5 6.9 0.2 0.7 6.4 0.5 0.6 14.6 49.6 24.0 24.4 11.5 8.3 7.9 12.0 11.6 11.4 ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9;non-classical monocyte: 5.8" "Lineage enriched" "Detected in many" 4 "monocytes: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved "CAB037021: AB_1841237" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.11e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-2)" 10.3 7.1 15.5 4.4 19.1 2.8 7.6 15.5 21.8 9.3 7.2 28.3 6.7 3.1 9.5 8.4 6.8 11.5 7.7 8.3 15.0 10.9 7.0 3.7 8.8 4.6 15.8 12.0 12.4 7.5 14.2 4.2 8.5 15.9 9.0 4.8 8.5 5.3 11.0 13.5 7.8 3.6 9.9 28.3 7.1 5.5 33.0 14.6 2.0 7.0 1.4 3.8 7.7 6.3 0.1 1.4 0.5 6.9 0.4 1.6 0.6 8.6 8.9 12.8 1.8 7.5 14.2 0.0 7.2 8.9 7.5 7.1 0.1 1.8 0.0 3.8 9.2 4.1 0.0 1.4 7.1 7.1 9.3 0.2 3.8 0.0 9.8 0.0 4.4 9.2 11.2 3.8 3.2 5.2 0.0 0.0 6.3 2.4 0.0 0.4 1.9 2.3 0.5 0.0 0.0 5.4 3.8 3.2 13.3 11.3 1.4 4.0 8.8 3.3 8.3 0.0 1.1 2.8 4.3 0.0 0.0 0.0 1.1 0.0 2.6 0.0 1.5 0.3 0.6 6.9 0.2 0.1 1.0 1.0 1.4 0.1 1.6 1.0 0.5 0.4 5.8 0.1 0.2 0.6 15.5 19.1 15.5 21.8 15.0 10.9 15.8 12.0 15.9 14.6 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836116-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved "HPA040474: " "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favourable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.0 11.7 11.8 8.4 15.4 2.9 7.4 21.3 20.4 7.9 13.8 9.0 9.0 7.9 5.3 9.5 33.9 6.7 9.6 14.1 11.8 8.9 13.4 9.3 6.4 7.9 11.2 15.3 4.9 14.7 12.1 12.3 5.7 21.1 8.2 14.4 10.4 10.4 7.4 19.1 24.6 20.3 7.2 5.8 9.9 11.1 6.0 7.6 4.2 6.1 10.9 13.7 8.6 10.6 3.8 4.2 3.8 7.8 5.8 12.6 4.9 3.8 10.5 5.5 9.5 6.3 4.1 3.6 3.1 4.5 6.4 7.0 4.1 8.8 8.3 5.9 3.4 3.9 15.4 4.3 2.7 16.0 15.2 24.9 13.5 5.0 9.2 5.9 15.9 5.5 8.5 5.6 5.3 9.7 6.9 9.1 5.2 5.8 4.3 6.1 6.2 5.4 12.8 6.7 15.9 4.1 4.9 10.3 13.0 6.0 5.7 19.0 8.3 14.9 5.4 8.6 5.5 8.4 6.6 12.6 11.4 6.1 4.8 17.4 7.4 3.8 3.6 1.4 12.6 7.8 10.1 3.8 7.4 10.3 4.0 3.5 8.1 5.5 0.9 5.8 6.2 4.2 9.7 4.9 11.8 15.4 21.3 20.4 11.8 8.9 11.2 15.3 21.1 7.6 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 4.3 4.8 5.1 4.7 8.3 10.3 4.2 4.3 5.4 11.9 2.8 5.9 6.0 2.1 10.7 10.9 2.8 12.3 3.1 13.1 5.2 3.0 5.4 3.4 5.5 4.2 3.1 4.2 4.5 3.6 13.5 19.7 9.0 5.8 4.4 2.8 6.7 4.2 4.5 1.4 3.5 3.3 5.1 5.7 4.4 3.4 27.5 3.4 6.3 7.1 1.7 8.4 4.0 6.0 6.4 5.1 10.7 6.3 2.6 10.3 5.2 7.2 1.7 2.6 3.0 1.1 1.7 4.5 2.5 2.6 3.0 2.6 0.9 2.1 8.4 1.4 5.7 3.7 3.2 1.9 2.8 1.1 0.9 1.6 5.3 2.8 3.9 5.5 1.7 1.6 2.2 14.7 3.0 2.1 1.8 7.0 2.2 5.8 6.9 4.4 3.2 3.0 1.5 8.4 3.7 6.4 7.0 1.3 9.7 2.5 1.2 2.0 2.9 1.8 6.1 1.9 2.2 13.0 2.0 4.2 7.9 3.5 10.8 5.8 2.3 5.7 5.8 5.8 8.0 6.3 6.5 5.6 8.6 7.2 5.1 6.4 6.5 9.2 10.7 2.6 3.2 4.6 10.3 5.2 5.1 8.3 4.3 5.4 5.2 3.0 3.1 4.2 5.8 3.4 UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730366-124749273 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Supported Cytosol Cytosol "HPA036178: AB_10673002, HPA036179: AB_10673615" "unprognostic (6.41e-2)" "unprognostic (6.70e-2)" "unprognostic (1.79e-2)" "unprognostic (1.13e-3)" "unprognostic (2.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.15e-3)" "unprognostic (5.51e-2)" "unprognostic (4.85e-3)" "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "prognostic unfavourable (9.20e-4)" "unprognostic (2.18e-2)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 8.4 12.2 4.9 6.8 6.8 4.8 8.0 9.3 7.6 5.9 9.1 8.5 5.2 8.4 6.8 6.7 13.2 8.2 6.6 3.6 4.0 3.9 9.6 20.7 5.2 10.1 7.3 3.6 8.9 19.0 9.5 9.3 11.6 4.7 6.4 7.1 6.4 8.9 4.0 10.9 9.5 8.5 5.5 5.9 9.8 8.3 6.8 6.2 10.6 7.4 12.0 9.3 7.8 6.4 16.6 13.1 4.6 9.8 10.2 13.0 7.9 1.4 4.3 5.0 2.0 3.0 3.4 5.2 7.4 2.3 3.1 2.6 3.7 2.0 3.8 8.2 2.9 8.3 7.0 2.4 5.0 4.3 4.0 7.7 2.8 2.6 2.6 8.0 5.9 3.8 2.3 1.9 3.9 1.4 3.5 1.8 2.3 3.3 9.9 1.5 10.9 2.8 6.5 5.9 3.1 2.5 2.4 4.0 2.6 11.1 4.0 4.1 4.0 3.0 14.2 2.5 5.0 6.8 2.9 7.4 10.1 10.3 2.8 3.3 2.5 4.5 9.0 4.6 12.5 9.8 12.1 13.7 8.9 11.3 13.1 16.6 13.0 10.4 0.6 10.2 8.0 9.7 10.3 7.9 4.9 6.8 9.3 5.7 4.0 3.9 7.3 3.6 4.7 6.2 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108733 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 102.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA054040: , HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavourable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavourable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.7 8.4 2.8 12.6 4.2 17.6 7.1 5.7 3.8 10.3 8.0 1.7 2.1 7.5 2.8 4.2 37.7 3.3 8.5 7.0 2.3 3.3 12.4 9.1 18.3 17.4 5.8 1.4 2.9 5.8 2.4 5.0 28.9 5.5 3.0 7.6 2.9 7.5 2.1 5.1 2.0 9.7 5.2 3.9 13.9 2.5 1.8 4.8 1.2 6.2 34.0 19.4 7.9 19.6 0.6 8.2 15.7 22.0 5.7 19.7 16.0 6.5 7.8 0.8 1.6 2.6 1.2 8.0 3.2 4.4 4.1 5.1 3.2 3.1 0.0 1.1 2.6 4.5 1.5 13.0 2.6 1.3 1.4 0.2 1.8 1.3 2.4 0.2 0.5 1.6 6.3 1.8 102.5 2.6 0.4 3.8 2.1 0.7 0.0 1.1 3.1 6.8 0.0 1.7 1.7 9.4 3.3 0.7 0.7 3.3 0.9 23.7 0.8 0.2 3.7 9.6 8.2 2.6 8.1 7.4 9.9 1.1 9.7 0.9 23.2 15.7 22.0 15.1 19.7 16.7 12.5 0.2 12.6 13.5 8.2 0.6 13.0 12.0 9.1 5.7 15.9 0.7 11.2 16.0 2.8 4.2 5.7 3.8 2.3 3.3 5.8 1.4 5.5 4.8 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 40.1;liver: 22.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.0;REH: 1.5" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 1.2 0.4 1.8 0.3 4.1 0.3 1.6 6.9 2.0 0.4 0.3 1.5 0.7 0.3 1.2 2.4 1.0 0.4 2.5 0.8 2.9 1.2 40.1 22.1 0.3 0.4 1.2 0.9 0.6 0.4 0.3 3.9 0.4 1.3 2.3 0.3 1.1 1.7 0.7 0.3 0.6 0.4 0.3 2.3 0.3 0.3 0.4 1.0 0.0 0.5 0.0 0.7 0.4 0.2 0.8 0.0 1.0 0.1 0.0 0.2 0.0 0.3 0.2 0.6 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.1 1.2 1.3 1.5 0.3 0.0 0.3 0.6 0.7 0.4 0.5 0.5 0.0 0.8 0.2 0.0 0.2 0.3 0.0 0.0 1.3 0.1 0.4 0.4 1.3 0.4 1.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 1.8 4.1 6.9 2.0 2.9 1.2 1.2 0.9 1.3 1.0 VRK1 ENSG00000100749 "Vaccinia related kinase 1" Q99986 14 96797304-96931722 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavourable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 6.0 4.4 7.1 9.8 17.1 39.0 8.7 8.6 10.2 6.1 7.8 4.4 4.1 5.2 5.9 5.7 9.4 6.9 3.3 6.0 7.4 6.5 6.2 4.3 4.5 18.3 6.9 6.1 5.9 3.7 3.8 5.1 7.1 6.7 5.3 9.1 4.1 4.8 4.1 4.3 6.4 6.9 5.4 6.1 15.7 6.7 33.3 6.9 33.0 4.9 6.1 18.4 5.9 5.7 20.8 13.5 20.1 9.5 28.5 22.3 12.5 15.7 9.1 22.5 10.0 2.7 5.0 14.0 11.9 9.3 19.1 19.0 10.8 15.6 40.1 8.1 7.0 17.5 21.0 15.5 26.3 22.8 11.3 25.0 6.0 11.1 2.9 48.0 15.7 2.7 2.8 14.4 10.6 13.2 21.2 25.4 16.4 18.0 38.1 20.7 14.4 17.3 35.7 39.4 13.6 8.7 16.2 15.9 9.0 10.5 10.8 8.0 12.3 19.0 7.1 8.7 7.8 15.0 11.9 13.3 15.7 38.8 13.6 21.0 10.3 20.1 7.6 14.5 15.1 9.3 18.4 20.3 17.6 18.5 9.9 20.8 19.1 19.3 4.5 28.5 9.5 13.5 22.3 12.5 7.1 17.1 8.6 10.2 7.4 6.5 6.9 6.1 6.7 6.9 VRK2 ENSG00000028116 "Vaccinia related kinase 2" Q86Y07 2 57907651-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: " "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavourable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 18.7 17.7 10.9 21.9 28.3 14.9 16.1 2.4 15.1 15.6 13.5 27.3 16.3 9.9 18.4 16.7 26.8 13.2 10.9 21.6 14.4 8.9 12.4 15.2 15.6 19.5 29.2 13.5 14.2 20.0 16.1 18.7 16.1 18.7 15.7 15.6 9.3 20.5 17.6 21.5 12.8 12.9 20.1 19.0 20.1 13.5 12.5 31.2 13.6 17.4 16.7 23.0 18.1 19.4 19.7 17.0 21.6 21.3 11.3 12.2 9.2 14.1 9.5 1.1 6.3 7.1 13.1 19.6 13.1 13.2 9.1 9.3 19.3 15.1 17.3 17.3 11.5 10.8 13.7 14.3 13.7 31.1 9.2 19.5 7.6 13.8 11.3 16.5 11.6 7.2 17.1 14.6 21.0 26.1 19.1 11.1 15.1 8.1 0.1 12.7 12.0 4.8 18.9 4.8 11.8 15.1 11.7 3.8 0.1 20.8 12.4 10.5 8.7 10.2 14.5 0.2 30.2 8.1 0.2 16.4 12.9 9.3 7.3 20.5 15.0 13.7 16.8 21.6 10.1 21.3 12.2 19.7 9.8 11.8 16.6 19.0 7.4 9.5 6.0 11.3 20.6 17.0 11.5 9.2 10.9 28.3 2.4 15.1 14.4 8.9 29.2 13.5 18.7 31.2 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573681-9593457 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004619, HPA068845" Approved Approved Nucleoli Nucleoli "CAB004619: AB_628447, HPA068845: " "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavourable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 6.9 3.5 2.0 26.1 2.1 6.6 27.4 5.3 1.6 12.8 18.0 2.5 15.4 3.7 21.9 14.3 22.1 12.4 20.2 23.0 2.0 2.2 6.8 19.3 10.2 10.9 1.8 1.2 11.1 4.4 4.9 6.1 42.7 4.7 17.0 4.7 5.9 12.8 17.8 12.0 33.3 10.4 22.9 2.4 8.0 12.5 28.3 2.0 35.9 12.0 26.8 26.4 19.8 14.7 8.5 0.1 6.4 0.0 2.1 7.8 0.6 14.2 5.5 21.2 11.7 18.6 9.3 42.0 17.6 13.6 9.9 9.8 10.1 17.5 33.4 6.6 7.7 17.3 14.5 6.8 12.7 11.9 11.9 13.1 8.9 6.7 2.0 19.8 13.1 3.1 7.4 4.6 16.4 6.1 21.3 23.3 17.2 3.4 20.2 10.7 31.9 6.3 19.5 16.6 7.2 7.8 30.1 7.9 10.5 11.9 14.1 8.6 8.9 9.5 7.0 17.8 12.5 7.2 14.1 5.5 16.3 44.2 7.6 10.9 12.5 0.0 0.0 6.4 2.0 0.0 0.2 8.5 2.0 3.3 0.1 3.6 0.1 1.6 0.1 2.1 0.0 0.1 7.8 0.6 2.0 2.1 5.3 1.6 2.0 2.2 1.8 1.2 4.7 2.0 WEE2 FLJ16107 ENSG00000214102 "WEE1 homolog 2" P0C1S8 7 141708353-141731271 "Enzymes, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027418, HPA054280" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" 0.6 0.1 0.5 0.3 1.0 0.0 0.4 0.8 0.6 0.6 0.1 0.0 0.7 0.0 1.3 0.7 1.6 1.3 0.5 0.6 1.3 0.1 0.3 1.6 0.6 1.2 1.1 0.0 1.0 0.0 0.3 0.0 0.9 0.0 0.7 2.8 0.4 0.0 0.8 0.4 0.8 1.3 2.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.3 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.5 1.6 1.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.2 0.1 1.7 1.1 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.0 0.5 0.0 0.0 0.2 0.0 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752593-911452 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol Cytosol "HPA046541: , HPA059157: " "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 30.0 12.4 49.3 19.1 47.5 28.9 45.4 22.5 36.7 21.2 12.6 42.6 10.6 8.5 15.9 19.4 45.5 16.9 16.5 38.5 53.7 36.4 45.6 18.0 33.0 34.3 62.3 27.1 18.5 11.3 29.1 12.7 20.3 41.4 17.1 14.3 12.0 15.4 20.3 43.4 31.3 10.3 22.3 82.8 16.9 15.7 23.8 38.8 23.9 16.7 17.4 24.5 18.9 26.5 3.7 2.6 10.9 7.1 2.1 5.2 1.9 14.2 27.0 35.7 3.3 25.8 24.8 13.6 14.2 17.1 15.4 14.4 15.2 16.3 20.1 5.0 30.5 10.8 24.1 16.4 21.7 34.8 14.4 44.9 35.9 13.1 18.9 24.2 19.6 19.2 25.0 25.5 45.8 20.8 20.4 48.6 23.3 13.1 43.5 4.1 29.1 6.5 20.8 39.6 5.4 22.2 30.9 10.4 12.2 33.2 21.5 9.6 23.7 24.9 23.0 19.1 22.2 26.8 20.9 7.4 12.3 30.5 18.2 12.8 15.5 0.9 2.7 2.6 3.8 4.0 5.2 3.0 4.3 3.6 2.6 3.7 2.3 4.1 10.9 2.1 7.1 1.7 4.9 1.9 49.3 47.5 22.5 36.7 53.7 36.4 62.3 27.1 41.4 38.8 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;pancreas: 18.3;salivary gland: 19.5;skeletal muscle: 23.7" "Cell line enhanced" "Detected in many" "Daudi: 11.2;Hep G2: 18.4;SCLC-21H: 23.4" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 0.0 0.7 3.9 0.9 3.8 0.0 1.2 9.5 7.2 0.7 7.5 7.4 1.3 1.5 2.1 6.6 0.1 21.9 4.0 4.2 0.0 0.0 0.0 0.0 2.6 0.0 18.3 0.8 7.5 0.9 4.9 4.8 19.5 5.5 23.7 3.0 6.2 1.6 1.1 0.5 3.0 1.5 0.0 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 0.3 0.0 4.4 4.0 2.8 8.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 1.6 0.1 11.2 1.5 0.0 0.2 6.4 0.0 0.0 0.0 7.4 0.0 3.5 18.4 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 5.8 0.1 0.1 7.1 0.2 0.0 0.0 9.1 0.0 0.6 23.4 9.2 1.4 6.3 0.6 0.8 1.3 0.1 0.0 3.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.6;testis: 26.7" "Cell line enhanced" "Detected in some" "AF22: 5.8;AN3-CA: 4.4;HAP1: 6.7;NTERA-2: 11.9;SiHa: 5.8;U-2 OS: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.1;T-cells: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles Vesicles "HPA077678: " "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.9 5.0 3.9 0.9 4.3 0.8 1.7 3.0 3.6 1.5 0.7 1.7 13.9 1.0 1.3 31.6 1.1 1.8 1.1 1.5 3.9 3.4 2.8 8.7 0.9 1.0 2.3 3.0 5.7 0.9 2.2 14.0 1.2 3.9 2.2 0.7 1.3 1.2 4.8 0.7 0.9 0.7 1.5 3.3 1.0 1.2 26.7 3.5 0.0 1.7 0.0 0.8 1.3 1.9 1.1 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.0 5.8 4.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.1 0.2 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.8 0.8 0.0 1.1 0.2 1.9 1.8 5.8 0.0 0.7 0.5 0.0 0.3 0.0 5.2 0.0 1.2 0.0 4.0 0.0 1.6 0.0 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.1 1.9 0.4 0.1 0.1 0.0 0.0 0.0 0.1 3.9 4.3 3.0 3.6 3.9 3.4 2.3 3.0 3.9 3.5 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780678-42796936 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1;ovary: 14.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.4;K-562: 21.7;TIME: 21.0;WM-115: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.1 0.0 0.8 5.8 0.2 0.0 2.6 0.6 0.3 0.7 12.9 0.4 0.4 2.1 0.2 2.8 8.7 0.5 1.0 0.2 2.6 0.0 28.1 0.2 0.4 0.1 0.1 0.3 14.6 1.0 0.0 2.4 0.0 1.7 11.1 11.7 12.2 1.4 1.2 0.0 0.5 3.3 0.4 0.8 0.1 2.6 0.4 0.2 0.0 0.0 0.2 2.0 0.3 0.4 0.4 0.0 0.0 0.3 0.0 1.0 0.0 1.2 0.6 0.2 0.0 0.2 0.1 2.9 7.2 2.8 2.7 0.8 0.4 0.5 0.2 4.3 19.4 0.0 0.1 0.2 4.7 0.4 0.9 0.0 0.0 2.8 4.6 0.0 0.4 2.5 0.4 3.9 1.2 0.2 21.7 0.7 0.0 0.6 0.0 0.5 0.2 4.9 0.3 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.9 1.4 1.5 21.0 0.2 1.9 0.2 0.1 3.5 3.0 0.6 0.0 1.2 14.1 0.0 0.3 0.0 0.0 0.0 0.7 0.4 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.3 2.6 0.0 0.1 0.3 1.7 0.2 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342738-86478420 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favourable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 15.4 9.1 9.7 15.6 14.1 5.2 20.9 8.5 9.5 11.5 16.9 7.5 21.1 8.7 11.9 19.3 11.7 7.2 22.0 40.7 8.7 8.5 16.9 37.2 10.2 15.9 10.0 7.8 10.1 11.3 40.7 7.3 15.6 12.7 17.8 11.3 8.9 11.8 9.4 58.0 13.8 13.0 18.4 9.9 19.1 11.4 10.4 9.5 11.1 11.2 18.0 12.5 14.5 12.3 3.7 2.6 6.5 2.8 2.9 10.4 2.3 22.9 10.8 7.5 5.3 9.4 9.3 6.9 8.4 8.9 6.7 8.0 7.6 14.1 9.9 5.7 14.3 19.7 10.5 13.4 11.6 12.2 8.4 11.3 9.6 17.8 6.9 4.5 5.9 8.4 17.2 7.3 13.6 29.4 5.9 11.6 11.3 11.4 10.8 3.4 4.5 12.2 7.1 9.0 8.7 15.0 17.6 2.2 5.2 8.3 42.1 8.9 12.5 4.2 33.8 10.0 11.9 10.6 4.3 13.8 8.4 10.1 12.4 0.8 7.6 6.5 2.8 4.8 7.2 2.4 6.0 3.7 8.7 7.1 1.9 3.6 10.4 6.3 1.7 2.9 2.8 2.6 8.0 2.3 9.7 14.1 8.5 9.5 8.7 8.5 10.0 7.8 12.7 9.5 WWP2 AIP2 ENSG00000198373 "WW domain containing E3 ubiquitin protein ligase 2" O00308 16 69762306-69941741 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-3)" "unprognostic (2.86e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.14e-1)" "unprognostic (7.50e-2)" "unprognostic (2.08e-2)" "unprognostic (9.81e-2)" "prognostic favourable (5.87e-11)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" 21.8 27.0 18.0 21.5 24.4 31.0 19.1 19.1 29.0 18.9 22.8 29.7 19.6 23.9 31.9 17.2 21.3 23.9 19.3 12.2 18.0 17.4 26.9 14.9 22.7 20.6 20.0 15.9 22.5 27.3 34.1 15.9 24.1 21.7 17.7 20.7 28.1 29.0 19.4 17.6 24.4 25.3 15.3 19.7 26.2 24.1 17.0 18.4 25.2 19.7 14.6 37.7 16.5 17.3 7.1 8.2 28.0 15.5 4.6 9.5 8.1 12.5 12.7 8.3 8.6 7.0 5.9 12.7 8.4 9.8 14.6 15.4 11.7 9.7 14.6 9.2 14.8 15.0 10.9 12.7 11.1 6.8 9.4 8.1 7.8 20.2 13.2 14.3 12.1 8.6 9.5 19.9 13.9 13.4 12.3 8.3 9.3 22.2 7.8 16.0 11.6 5.7 17.6 7.0 24.8 14.2 12.2 10.3 11.3 36.0 10.4 7.7 16.2 17.7 13.3 11.4 16.8 15.9 10.1 19.2 12.8 22.1 12.3 12.2 20.1 18.2 10.0 15.6 9.5 12.9 7.3 6.4 7.1 7.6 8.2 7.1 7.5 5.1 28.0 4.6 15.5 4.0 6.3 8.1 18.0 24.4 19.1 29.0 18.0 17.4 20.0 15.9 21.7 18.4 XIAP "API3, BIRC4, hILP" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913979 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: " "prognostic unfavourable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 17.4 14.4 20.0 18.1 20.2 12.0 15.9 21.3 18.9 17.2 19.4 14.5 22.9 16.1 17.4 17.0 18.9 12.6 14.7 15.7 18.9 22.1 19.8 19.4 16.5 15.5 18.8 14.6 13.9 19.7 36.6 26.1 18.2 15.9 15.6 16.8 16.9 14.6 22.9 21.5 14.2 23.4 17.0 19.0 15.8 16.2 7.0 12.3 13.9 24.3 11.4 14.0 15.4 20.5 5.7 4.3 11.1 3.9 3.3 5.5 1.9 11.5 9.9 7.8 6.7 9.2 11.9 10.2 12.6 9.4 6.9 5.9 4.4 13.6 10.8 18.7 10.7 4.3 11.5 7.9 12.7 11.2 6.3 7.3 8.3 6.7 11.7 13.2 15.2 8.2 12.3 11.4 14.7 9.5 11.5 12.5 13.3 12.0 7.3 6.4 6.4 7.8 7.9 9.1 11.4 10.4 16.8 5.3 7.7 17.2 10.0 10.1 6.1 6.5 11.7 0.3 4.7 20.6 14.0 10.5 10.5 12.0 14.2 9.4 8.7 11.1 2.6 3.5 5.0 2.3 4.7 4.6 3.8 5.5 1.4 5.7 4.4 3.0 8.2 3.3 3.9 4.3 2.5 1.9 20.0 20.2 21.3 18.9 18.9 22.1 18.8 14.6 15.9 12.3 XXYLT1 "C3orf21, FLJ35155" ENSG00000173950 "Xyloside xylosyltransferase 1" Q8NBI6 3 195068279-195271167 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 12.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" 34000 "unprognostic (1.39e-2)" "unprognostic (2.31e-2)" "unprognostic (3.42e-2)" "unprognostic (2.32e-3)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "unprognostic (6.29e-3)" "unprognostic (5.67e-2)" "unprognostic (5.50e-2)" "unprognostic (6.57e-2)" "unprognostic (3.13e-2)" "unprognostic (4.13e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (1.07e-1)" "unprognostic (2.23e-2)" "unprognostic (8.20e-2)" "unprognostic (1.07e-2)" 10.1 7.0 7.4 10.3 8.8 8.1 10.2 8.1 13.6 11.1 8.5 11.0 3.6 7.0 14.5 8.0 16.7 9.6 9.5 8.3 6.7 9.5 7.0 5.2 10.3 10.7 8.5 8.7 11.3 4.6 9.9 8.7 16.3 10.7 7.9 7.8 9.8 7.8 9.5 3.4 13.4 6.7 13.8 7.5 9.1 6.8 6.6 6.1 8.1 7.0 10.0 10.8 9.7 11.7 2.3 12.7 2.1 4.8 2.1 1.9 1.4 7.5 6.5 19.5 31.8 11.2 9.7 6.9 12.0 8.3 11.9 10.4 6.8 5.3 9.0 12.9 9.4 9.1 8.2 7.1 6.3 5.0 12.9 8.9 5.3 7.3 5.2 11.1 14.5 6.9 9.4 4.2 4.7 25.0 10.9 2.7 4.0 18.8 7.4 14.3 15.0 11.4 12.7 8.0 9.7 8.7 2.5 18.0 16.6 7.4 5.9 7.5 17.9 6.3 16.5 7.0 1.7 6.7 12.2 2.2 6.8 21.9 4.5 14.4 7.4 1.1 4.8 2.1 1.9 3.4 1.6 1.7 1.7 1.9 3.3 2.3 1.7 1.7 1.4 2.1 2.9 12.7 0.9 1.4 7.4 8.8 8.1 13.6 6.7 9.5 8.5 8.7 10.7 6.1 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 34.0" "Cell line enhanced" "Detected in many" "Hep G2: 21.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 6.4;monocytes: 3.6;T-cells: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favourable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 2.3 3.2 2.7 1.9 3.4 2.5 3.0 10.3 4.7 2.7 5.9 2.3 1.6 5.8 3.7 3.6 3.1 1.9 2.5 1.5 1.8 1.8 11.3 34.0 1.8 1.3 1.9 3.3 2.8 6.1 1.2 3.1 1.4 4.1 2.1 5.1 3.0 7.1 1.8 1.3 1.9 9.8 3.6 2.0 1.6 3.7 2.1 1.6 2.3 1.5 1.8 1.3 2.7 2.9 0.4 6.4 1.1 3.6 0.9 3.9 1.1 3.0 5.7 2.1 4.6 2.9 3.2 5.1 4.3 1.6 3.9 3.8 7.7 3.2 2.7 1.1 5.4 2.1 6.2 2.5 4.2 3.8 4.8 5.3 4.4 21.0 1.8 7.5 5.7 2.1 4.3 5.2 2.1 3.5 14.3 5.2 3.7 1.6 6.4 1.0 3.0 6.9 3.2 4.2 3.8 0.4 4.7 2.6 2.4 2.5 11.5 9.3 5.5 4.3 1.3 7.3 5.7 11.1 1.8 2.8 4.5 7.3 3.9 6.3 5.3 0.5 2.2 0.7 1.5 3.6 1.0 0.3 1.2 0.8 6.4 0.4 1.5 1.5 1.1 0.9 2.9 1.3 3.9 1.1 2.7 3.4 10.3 4.7 1.8 1.8 1.9 3.3 4.1 1.6 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470881 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.6" "Cell line enhanced" "Detected in many" "ASC diff: 18.8;U-2197: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" 30000 "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 5.7 5.9 6.3 21.6 3.1 5.9 7.0 3.8 6.7 8.0 7.4 1.4 0.9 3.9 7.4 3.0 4.9 3.2 4.4 3.8 6.3 4.2 1.9 0.9 2.9 7.5 4.3 2.2 5.5 2.6 0.2 1.8 5.4 2.6 4.4 4.9 3.4 2.6 4.3 1.3 4.1 4.7 5.1 3.9 6.3 3.2 3.0 2.1 4.6 2.7 6.7 6.6 4.7 4.2 1.2 0.8 1.2 3.6 0.9 0.7 0.5 0.0 0.1 2.6 0.0 18.8 11.7 3.2 8.4 4.3 0.9 0.4 0.1 0.2 2.0 0.0 10.1 0.2 0.0 1.7 1.5 4.0 0.2 2.5 0.0 0.0 0.2 3.6 3.4 4.3 0.2 5.4 0.8 0.0 0.3 7.9 0.9 0.3 0.0 3.9 2.8 0.0 1.2 0.0 0.4 0.0 3.8 0.7 5.1 0.6 2.6 0.5 0.6 2.3 0.0 8.8 1.0 19.3 0.0 8.8 0.5 3.8 9.8 4.1 7.4 0.6 0.6 1.2 0.6 2.5 0.7 1.2 0.5 0.3 0.8 1.2 0.5 0.4 0.3 0.9 3.6 0.2 0.7 0.5 6.3 3.1 3.8 5.3 6.3 4.2 4.3 2.2 2.6 2.1 XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346092-50363138 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 53.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016456 Approved "Nuclear bodies,Cytosol" "Secreted to blood" 990000 "Nuclear bodies" Cytosol "HPA016456: AB_1858907" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" 6.9 8.5 5.8 11.3 10.6 4.1 7.4 10.3 10.9 10.7 9.2 5.4 15.8 10.0 9.6 12.2 8.5 10.4 14.9 9.4 5.3 4.8 9.2 6.1 6.1 10.2 4.7 8.8 11.8 13.5 9.1 5.8 9.0 5.4 12.1 3.9 13.1 12.7 11.7 7.9 15.6 6.9 17.0 3.8 8.4 53.4 5.8 3.7 10.2 9.5 6.7 10.4 11.7 9.0 5.3 4.9 6.6 4.0 7.8 7.8 4.3 9.7 12.5 3.4 2.8 4.8 4.7 8.9 9.1 8.4 8.2 9.3 13.2 7.4 5.1 23.2 8.2 7.5 1.1 12.8 1.7 25.2 8.9 11.4 3.8 5.7 6.6 3.6 6.2 6.4 7.9 6.6 3.1 7.0 2.0 4.3 5.4 12.7 6.6 4.9 3.1 8.8 3.3 10.0 4.2 4.6 5.1 1.8 4.3 6.1 5.8 9.6 27.6 3.5 8.2 18.8 9.6 10.2 8.1 23.4 10.7 1.7 19.8 5.8 5.1 6.6 4.0 3.2 5.9 2.8 6.3 2.9 5.9 7.8 4.9 5.3 6.0 5.3 4.7 7.8 2.5 3.4 5.2 4.3 5.8 10.6 10.3 10.9 5.3 4.8 4.7 8.8 5.4 3.7 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 14.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" 4300000 "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 26.2 13.1 17.0 9.4 15.6 2.6 47.2 6.7 12.8 15.8 23.8 8.9 13.7 18.2 13.1 17.4 22.0 10.7 14.9 17.9 14.8 12.4 22.6 43.2 23.6 13.7 15.8 6.6 13.2 21.4 16.7 10.7 31.3 16.8 12.2 17.3 6.5 23.7 21.0 10.6 12.3 24.8 18.8 16.8 34.5 15.5 13.6 12.0 8.1 16.8 15.6 7.1 21.9 17.5 0.1 0.1 14.7 0.0 1.0 2.5 0.6 14.2 7.1 22.4 17.5 13.5 16.7 26.4 9.5 19.4 11.2 15.4 16.8 10.5 0.0 10.1 16.1 8.3 20.9 16.8 22.0 0.0 7.1 4.2 7.0 11.7 11.0 3.2 7.6 12.7 18.1 16.9 18.9 37.8 18.4 6.3 15.9 9.8 1.9 4.2 14.2 9.1 2.4 17.6 1.2 16.3 16.9 4.6 5.3 19.6 14.9 12.4 10.3 6.8 32.5 27.7 30.7 20.8 25.5 5.5 2.7 0.8 10.5 4.7 16.4 14.7 0.0 0.9 2.5 0.0 1.6 0.1 0.5 1.4 0.0 0.0 1.2 1.9 0.0 1.0 0.0 0.1 0.1 0.6 17.0 15.6 6.7 12.8 14.8 12.4 15.8 6.6 16.8 12.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713560-97739862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 37.4;lymphoid tissue: 107.1" "Cell line enriched" "Detected in some" 13 "MOLT-4: 61.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 41 "gdT-cell: 37.4;MAIT T-cell: 25.4;memory CD4 T-cell: 19.6;memory CD8 T-cell: 29.2;naive CD4 T-cell: 14.3;naive CD8 T-cell: 21.9;NK-cell: 26.4;T-reg: 19.9" "Group enriched" "Detected in many" 53 "NK-cells: 26.4;T-cells: 37.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002625, HPA003134" Enhanced "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favourable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favourable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favourable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavourable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 2.2 0.5 0.3 18.1 0.6 11.2 1.5 0.7 0.6 1.2 3.7 0.7 0.3 2.9 1.2 1.1 1.7 1.5 2.8 0.9 0.4 0.8 2.2 2.3 5.8 28.1 0.8 0.6 0.9 1.3 0.0 0.7 0.9 0.6 2.1 0.6 1.0 5.5 1.0 0.7 1.0 12.3 0.7 0.7 24.8 3.2 1.4 0.6 107.1 2.5 1.1 20.8 3.0 1.7 0.4 0.2 0.5 0.2 26.4 37.4 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 61.5 0.1 0.0 0.0 2.4 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.1 37.4 0.1 25.4 0.0 19.6 29.2 0.0 0.4 14.3 21.9 0.5 26.4 0.2 0.2 19.9 14.3 0.3 0.6 0.7 0.6 0.4 0.8 0.8 0.6 0.6 0.6 ZCCHC11 "KIAA0191, PAPD3, TUT4" ENSG00000134744 "Zinc finger CCHC-type containing 11" Q5TAX3 1 52408282-52553487 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027412, HPA027973" Supported Supported Nucleoli,Cytosol Cytosol Nucleoli "HPA027412: AB_1852281, HPA027973: AB_10603242" "unprognostic (2.74e-2)" "unprognostic (1.67e-2)" "unprognostic (1.19e-2)" "unprognostic (3.48e-2)" "unprognostic (1.36e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (9.00e-4)" "unprognostic (2.64e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-1)" "unprognostic (6.57e-3)" "unprognostic (3.11e-2)" "unprognostic (5.35e-3)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" 13.8 19.1 18.4 25.6 19.0 20.5 18.7 50.9 21.3 22.4 13.3 11.8 16.1 7.7 22.1 22.0 11.5 16.8 14.0 13.5 17.8 16.5 14.2 17.7 13.3 27.4 15.4 14.6 28.3 17.6 34.4 56.0 18.8 16.3 16.1 10.5 12.1 12.6 20.6 44.6 28.1 17.1 20.3 26.6 20.9 12.3 24.9 21.1 31.9 23.9 14.6 25.1 18.3 17.0 23.2 26.0 26.7 4.3 10.3 15.0 2.2 10.4 9.9 24.4 16.5 9.6 12.3 16.9 9.3 13.6 13.6 15.7 10.2 5.5 22.3 11.0 12.9 8.7 18.3 9.8 17.3 18.2 16.7 23.5 12.8 21.2 15.9 25.4 13.4 14.5 21.9 14.5 18.0 9.4 19.1 11.2 11.3 0.1 25.3 18.2 17.7 12.6 22.5 24.8 17.4 14.6 8.6 13.1 13.0 14.3 6.1 13.9 8.5 13.4 7.9 10.6 14.3 9.7 11.3 24.5 32.1 32.1 7.0 13.9 7.6 26.7 4.3 13.8 11.8 1.7 8.8 19.1 12.4 9.5 2.1 23.2 15.0 9.9 16.2 10.3 1.4 26.0 9.3 2.2 18.4 19.0 50.9 21.3 17.8 16.5 15.4 14.6 16.3 21.1 ZCCHC6 "FLJ13409, KIAA1711, PAPD6, TUT7" ENSG00000083223 "Zinc finger CCHC-type containing 6" Q5VYS8 9 86287733-86354454 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 42.1" "Group enriched" "Detected in all" 5 "granulocytes: 42.1;monocytes: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 11.2 9.3 7.7 22.6 11.2 17.0 17.3 9.7 13.7 10.8 13.5 5.6 12.8 9.4 8.6 8.1 23.1 8.3 10.3 10.1 9.4 5.2 7.4 33.1 16.3 19.5 9.8 5.1 9.0 12.9 9.2 18.6 33.3 9.0 19.3 10.8 4.5 14.0 13.6 12.5 30.9 15.6 9.7 13.6 22.2 11.7 10.3 10.7 23.3 8.7 15.2 16.9 13.7 14.3 4.4 4.3 42.1 15.7 4.5 5.7 2.9 9.8 10.7 6.4 9.2 16.3 24.8 7.8 13.5 13.2 6.0 7.0 4.8 8.8 14.1 12.3 8.9 17.5 7.5 7.6 8.9 16.5 4.0 10.1 11.3 9.0 13.9 11.5 14.8 16.4 16.0 9.5 11.3 10.0 9.5 15.3 16.6 10.6 9.6 7.0 5.2 7.2 4.9 11.1 6.5 10.6 19.4 4.6 3.7 8.2 10.9 4.7 4.1 5.2 15.4 5.7 6.9 10.1 9.2 17.7 13.7 10.5 13.6 6.9 7.5 11.5 7.1 7.1 5.7 9.1 4.9 4.4 3.2 4.1 4.3 4.4 3.7 4.0 42.1 4.5 15.7 2.0 3.0 2.9 7.7 11.2 9.7 13.7 9.4 5.2 9.8 5.1 9.0 10.7 ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394419-67416833 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 13.4;ASC TERT1: 14.9;U-138 MG: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 2.6;intermediate monocyte: 3.6;myeloid DC: 2.4;non-classical monocyte: 3.5" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol Cytosol "HPA042531: , HPA048659: " "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favourable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favourable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favourable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" 9.6 6.3 4.3 3.9 6.6 0.5 10.2 5.3 10.5 16.9 7.4 5.5 7.9 3.8 13.5 16.4 6.3 22.6 14.0 6.2 4.5 3.7 11.2 3.8 7.8 4.9 5.3 3.5 17.1 16.2 11.5 14.0 15.1 6.5 11.6 3.2 11.2 14.7 12.1 8.0 10.8 3.9 9.3 3.3 10.1 6.2 25.7 2.6 0.6 31.3 9.3 4.9 6.9 9.7 0.0 2.4 0.3 3.6 0.0 0.0 0.8 5.0 6.1 1.5 8.1 13.4 14.9 0.0 2.8 11.0 2.9 3.4 0.0 3.2 0.0 1.3 5.1 3.3 0.5 0.5 0.6 1.5 4.6 0.4 0.1 0.4 6.8 0.3 4.3 7.1 6.3 3.1 0.8 3.7 0.0 0.0 2.0 0.5 0.0 0.0 3.0 0.1 0.0 0.1 0.0 4.1 3.1 2.1 7.4 0.5 0.2 6.6 2.1 1.2 4.9 12.9 2.1 6.2 3.4 1.5 0.3 0.0 7.9 0.1 5.3 0.0 2.6 0.0 0.0 3.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.8 4.3 6.6 5.3 10.5 4.5 3.7 5.3 3.5 6.5 2.6 ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795606-850986 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2" "Cell line enhanced" "Detected in many" "T-47d: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057886, HPA069008" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA057886: , HPA069008: " "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" 1.8 1.4 3.4 1.0 4.2 0.7 2.7 11.0 3.8 1.6 1.5 6.3 1.0 9.5 1.7 2.9 3.2 10.3 1.2 6.4 4.2 3.8 2.0 2.6 7.5 1.0 15.2 1.9 1.5 1.9 1.8 7.8 1.2 10.9 2.7 1.2 1.0 1.4 3.4 2.1 2.7 1.7 1.0 5.0 2.4 5.9 6.3 6.1 1.0 1.1 2.3 1.8 1.0 1.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.3 7.4 4.1 0.8 1.3 0.3 5.5 0.3 0.1 0.2 0.1 1.0 0.3 3.0 0.8 0.1 6.9 2.2 0.0 0.1 9.0 4.8 0.3 2.6 3.7 0.3 4.3 0.3 0.4 0.3 0.9 1.0 0.0 0.7 1.7 0.2 3.3 0.4 2.6 7.3 2.9 4.5 2.8 4.1 0.2 1.5 4.1 0.7 0.2 0.1 3.1 11.5 0.7 0.4 0.2 6.9 3.9 0.1 5.5 7.7 0.9 0.3 8.9 0.2 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 4.2 11.0 3.8 4.2 3.8 15.2 1.9 10.9 6.1 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710360-766952 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell line enhanced" "Detected in some" "HAP1: 5.0;RPMI-8226: 4.4;SCLC-21H: 6.5;THP-1: 7.0" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "HPA057886, HPA069008" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA057886: , HPA069008: " "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favourable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.3 1.8 2.9 0.0 3.7 0.0 0.6 11.7 5.3 0.0 1.1 3.8 0.5 0.4 2.8 3.4 0.5 3.8 3.9 2.9 0.4 0.6 5.3 0.0 2.8 0.8 2.4 1.5 3.7 0.1 0.6 1.9 1.0 0.4 3.3 4.8 5.9 0.0 2.5 3.3 3.8 0.8 0.7 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 1.9 0.8 2.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.2 1.0 0.3 0.0 2.4 5.0 0.2 0.0 3.0 2.3 0.0 1.9 0.9 0.0 1.5 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 4.4 0.1 1.5 6.5 1.9 0.1 0.0 0.6 0.1 7.0 0.1 0.0 2.5 0.0 0.0 2.4 0.8 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type containing 12" Q96GR4 9 128720869-128724127 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 77.4" "Cell line enhanced" "Detected in many" "MCF7: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" Nucleoplasm "Intermediate filaments" "HPA059339: " "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 7.3 10.9 3.9 15.3 4.5 21.8 11.2 2.5 6.5 7.5 21.2 6.8 19.3 16.2 5.9 8.3 27.2 6.9 21.5 9.2 3.5 3.1 20.6 23.6 14.2 28.0 3.8 3.8 5.0 40.5 4.3 5.0 24.7 4.8 11.1 8.4 7.7 26.3 13.3 7.5 16.8 33.0 5.4 5.8 14.9 18.7 9.2 2.7 23.6 10.3 16.4 24.4 10.1 11.7 22.2 50.6 77.4 28.7 17.4 26.1 18.8 14.1 38.8 1.6 8.4 5.1 3.5 16.4 9.2 8.2 10.0 6.7 31.8 16.4 9.9 8.6 6.8 37.5 3.5 18.1 1.0 18.2 9.3 5.2 29.5 13.9 10.3 8.7 24.1 5.6 12.6 8.2 3.1 7.4 5.2 25.2 1.9 54.5 11.9 17.4 7.2 32.1 5.4 5.8 28.4 7.6 13.3 11.6 8.4 12.4 17.2 4.8 26.5 9.3 7.4 0.0 10.5 7.1 12.2 16.3 28.8 4.4 16.8 10.0 11.0 39.2 26.5 77.4 23.5 24.7 20.3 20.3 21.8 22.5 21.0 22.2 22.7 20.6 56.8 17.4 28.7 50.6 26.1 18.8 3.9 4.5 2.5 6.5 3.5 3.1 3.8 3.8 4.8 2.7 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type containing 13" Q8IUH4 11 19117099-19176422 "Enzymes, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Enhanced Vesicles Vesicles "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.7 5.2 6.3 9.3 8.0 6.8 7.3 13.2 9.7 8.8 13.2 5.8 7.1 8.7 6.4 5.6 36.4 10.5 6.9 7.7 6.2 7.1 10.8 2.3 4.7 6.9 5.4 5.2 5.8 14.0 10.9 20.1 9.4 9.4 7.1 14.7 6.4 11.2 5.9 2.1 14.9 12.3 4.9 4.7 6.3 14.4 11.2 4.8 15.0 7.7 18.2 27.5 15.3 14.5 6.3 4.3 23.4 5.8 4.3 7.5 3.5 15.8 7.5 7.2 6.1 2.6 3.0 6.9 7.6 7.0 8.5 9.9 4.5 3.8 8.1 5.3 6.3 24.2 10.3 5.0 9.4 10.0 9.0 4.2 4.8 3.6 6.0 5.7 7.3 3.4 5.9 3.6 5.0 53.8 4.0 4.1 8.8 5.1 7.3 4.7 6.0 7.0 8.2 10.0 1.9 8.8 10.5 12.6 9.2 9.1 11.1 4.1 5.2 6.7 15.4 7.6 5.4 11.6 6.1 3.5 10.7 7.5 9.1 5.9 13.2 7.4 3.5 23.4 6.8 5.8 6.1 6.3 5.3 7.5 4.3 4.2 5.1 6.5 4.4 4.3 4.6 4.2 6.8 3.5 6.3 8.0 13.2 9.7 6.2 7.1 5.4 5.2 9.4 4.8 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type containing 14" Q8IZN3 6 157381133-157678146 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 4.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063754 Approved Approved Nucleoli,Mitochondria Nucleoli Mitochondria "HPA063754: " "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favourable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 6.4 3.9 9.0 4.4 10.8 4.8 3.6 15.6 16.2 7.4 5.3 22.1 2.9 6.2 22.6 2.6 4.2 4.8 5.3 11.1 10.6 8.8 6.9 8.7 6.4 4.8 15.8 7.1 3.3 5.7 12.7 3.7 5.1 15.3 7.9 4.0 9.1 4.6 3.8 4.7 3.3 8.6 13.7 22.0 6.4 8.1 6.3 11.8 0.7 3.8 1.5 5.7 5.3 5.0 1.5 4.2 0.0 0.1 0.4 0.9 0.4 1.7 1.8 0.5 2.5 1.4 1.0 5.8 2.7 2.5 1.9 1.7 2.2 1.2 4.2 0.9 2.1 0.8 1.4 1.4 1.7 32.7 2.1 8.2 0.6 1.0 1.9 1.1 1.8 0.7 1.5 2.0 0.8 2.9 6.6 3.1 1.1 1.1 0.7 2.7 1.0 2.1 0.1 0.3 2.5 3.9 0.7 4.2 1.2 3.1 2.0 2.3 0.3 1.3 4.0 2.9 2.1 5.6 3.4 0.7 0.8 0.6 1.0 2.9 3.1 0.0 0.1 0.0 0.5 0.0 0.9 1.5 0.4 0.4 0.0 0.8 0.0 0.3 0.0 0.4 0.0 4.2 0.0 0.4 9.0 10.8 15.6 16.2 10.6 8.8 15.8 7.1 15.3 11.8 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type containing 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 5.6;K-562: 3.5;LHCN-M2: 3.9;MOLT-4: 4.1;NTERA-2: 3.7;RH-30: 5.7;RPTEC TERT1: 3.1;SH-SY5Y: 4.7" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003618 Uncertain Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA003618: AB_2217686" "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 3.0 5.4 4.9 1.5 6.8 1.1 5.3 6.2 9.9 5.8 3.4 3.9 2.4 1.3 6.5 3.7 3.2 4.5 3.3 5.4 5.9 8.7 5.3 1.2 4.1 1.6 4.8 5.3 8.5 4.7 5.0 8.7 0.7 7.0 4.0 2.3 5.4 12.7 6.9 1.6 2.8 1.8 5.2 6.4 2.9 2.1 2.6 3.1 2.0 6.6 2.1 1.5 2.6 3.1 0.3 0.4 0.7 0.2 0.5 1.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 3.9 0.0 4.1 0.1 3.7 0.0 0.0 5.7 0.0 3.1 0.0 1.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.0 0.0 0.7 2.8 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.0 0.1 0.3 0.6 0.0 0.0 0.2 1.6 1.1 0.7 0.5 0.1 0.4 0.0 0.3 4.9 6.8 6.2 9.6 5.9 8.7 4.8 5.3 7.0 3.1 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type containing 16" Q969W1 10 97446131-97457370 "Enzymes, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 12.0 13.7 15.9 10.8 17.3 6.4 17.9 17.6 24.6 17.1 17.9 15.6 18.1 15.1 15.5 21.2 17.6 11.5 14.4 18.1 13.2 11.0 23.3 37.4 20.8 11.1 10.9 13.0 15.1 22.5 21.8 15.4 30.7 10.5 16.0 18.9 18.1 28.5 14.1 20.7 14.0 15.7 17.6 8.5 13.2 19.4 16.4 10.8 14.7 19.6 15.4 16.1 15.1 20.0 9.3 14.2 9.4 10.4 13.0 12.0 5.8 21.4 25.2 16.8 20.7 26.9 18.5 17.6 23.6 31.5 27.3 26.1 19.6 19.2 18.9 27.3 34.5 25.3 21.1 33.4 24.4 18.7 24.5 12.0 17.7 18.6 21.6 14.3 17.7 20.6 22.1 31.9 23.0 28.0 9.6 14.4 34.5 20.5 21.6 19.6 13.7 21.9 14.8 17.1 17.4 23.1 9.9 8.2 11.7 14.4 14.9 12.8 19.7 14.0 17.1 17.2 16.0 11.1 27.6 13.8 22.3 11.6 19.9 22.2 9.0 0.3 9.8 9.4 7.0 10.4 8.0 8.2 12.0 11.1 14.2 9.3 9.9 9.8 0.5 13.0 10.4 10.9 9.4 5.8 15.9 17.3 17.6 24.6 13.2 11.0 10.9 13.0 10.5 10.8 ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type containing 17" Q8IUH5 12 76763588-76853696 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 16.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016807, HPA058674" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA016807: AB_1858999, HPA058674: " "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavourable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" 7.9 7.8 10.0 5.8 14.0 11.3 8.8 18.1 18.1 8.0 5.9 9.2 3.8 3.6 12.0 6.8 6.4 7.0 5.5 6.4 8.7 6.5 9.1 13.1 5.4 7.1 11.3 10.7 11.5 5.2 9.5 10.3 8.7 13.2 7.9 5.4 5.9 5.7 7.3 5.4 5.9 6.4 8.0 10.0 7.1 6.1 6.4 11.6 7.5 6.2 4.1 5.7 5.6 6.3 3.8 16.3 5.8 2.2 1.7 3.6 1.4 5.7 7.1 22.2 11.3 13.4 14.2 10.9 11.7 9.7 7.8 6.9 5.6 4.2 8.0 7.1 11.3 5.5 8.8 7.3 12.2 6.7 9.3 11.6 8.7 8.5 9.0 11.6 10.4 13.3 7.7 7.3 11.0 8.9 12.5 3.7 10.1 5.4 8.3 15.6 16.4 8.1 11.3 7.9 8.7 9.0 8.9 8.7 15.1 12.9 4.7 7.5 10.5 11.7 12.3 10.7 8.1 6.5 6.6 6.0 5.8 8.7 4.0 5.5 11.0 5.7 2.1 5.2 3.6 2.2 2.9 2.6 2.9 2.7 2.6 3.8 3.1 2.6 5.8 1.7 2.1 16.3 1.2 1.4 10.0 14.0 18.1 13.8 8.7 6.5 11.3 10.7 13.2 11.6 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type containing 18" Q9NUE0 1 26826710-26857602 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 86.2" "Cell line enhanced" "Detected in all" "HDLM-2: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 20 "granulocytes: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040234 Approved Approved Microtubules Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavourable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavourable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 20.5 8.2 13.3 22.7 18.9 86.2 39.0 21.4 18.4 10.2 13.0 11.9 7.5 11.7 12.4 6.4 19.3 9.9 13.5 9.8 13.5 20.0 7.8 14.5 16.2 23.5 16.3 12.8 9.6 10.8 7.1 10.5 20.3 15.2 10.7 13.9 11.2 14.1 9.8 8.7 16.3 12.2 16.6 10.4 27.1 10.8 7.0 9.5 11.7 14.6 10.1 23.3 16.5 24.7 0.2 0.4 27.0 0.6 0.5 1.3 0.2 18.1 8.1 13.2 9.1 11.0 7.7 13.0 10.9 13.0 19.3 14.4 7.4 11.7 8.4 7.0 14.5 12.8 14.0 6.5 16.6 53.1 11.9 8.1 5.9 10.3 9.5 7.2 7.1 6.6 8.9 17.7 11.8 10.7 8.4 17.5 7.6 8.8 13.6 5.8 12.6 7.8 11.3 11.4 8.9 8.1 4.6 6.1 7.4 7.3 5.6 8.0 5.0 7.1 9.1 13.3 10.3 21.8 12.5 20.9 14.9 7.2 7.6 13.1 9.0 0.0 0.2 5.1 0.9 0.6 0.7 0.2 0.6 0.6 0.4 0.1 0.4 0.4 27.0 0.5 0.4 0.2 1.3 0.2 13.3 18.9 21.4 18.4 13.5 20.0 16.3 12.8 15.2 9.5 ZDHHC19 MGC33345 ENSG00000163958 "Zinc finger DHHC-type containing 19" Q8WVZ1 3 196197449-196211437 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 53.4" "Cell line enhanced" "Detected in some" "HMC-1: 1.6;K-562: 1.1;NTERA-2: 1.1;SH-SY5Y: 1.8;THP-1: 2.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "eosinophil: 2.4;memory B-cell: 3.9;naive B-cell: 5.2;neutrophil: 3.4" "Group enriched" "Detected in many" 24 "B-cells: 5.2;granulocytes: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (1.15e-1)" "unprognostic (7.50e-4)" "unprognostic (2.87e-3)" "unprognostic (6.72e-3)" "unprognostic (3.79e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (3.66e-3)" "unprognostic (4.63e-2)" "unprognostic (6.52e-2)" "unprognostic (2.86e-2)" "unprognostic (3.46e-7)" "unprognostic (8.05e-4)" "unprognostic (4.71e-1)" "unprognostic (7.08e-3)" "unprognostic (4.28e-2)" 0.0 0.6 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 53.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.1 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 5.2 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type containing 2" Q9UIJ5 8 17156029-17224799 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023331 Uncertain "HPA023331: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favourable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.1 22.5 14.8 9.4 14.5 24.4 14.8 22.8 12.2 12.9 13.4 17.5 17.4 9.3 7.0 10.5 5.3 12.8 6.4 10.1 13.0 14.0 24.2 7.5 12.7 10.3 13.6 10.9 13.0 27.0 19.2 20.2 6.1 14.7 12.0 10.3 21.2 15.9 13.7 15.9 3.4 9.1 8.8 25.9 11.2 14.1 14.2 14.5 13.8 32.3 10.4 10.2 17.3 8.7 5.3 4.6 4.9 2.7 4.4 7.0 1.5 1.0 5.4 10.5 2.2 9.2 16.5 6.1 18.0 21.9 10.2 12.2 1.7 15.0 10.9 7.1 15.6 0.7 14.1 8.9 19.0 7.1 7.1 9.8 7.8 2.1 9.2 10.3 1.2 6.9 1.4 12.8 11.7 16.8 1.1 29.3 12.3 0.2 7.6 6.2 6.6 8.3 7.6 10.5 4.0 18.6 11.5 5.6 3.7 7.7 0.0 1.7 0.4 4.7 13.9 5.2 16.0 11.5 17.9 5.8 21.9 12.8 14.4 9.5 2.3 2.6 2.6 4.9 4.1 2.7 7.0 5.3 5.1 4.9 2.2 4.6 4.7 5.0 1.8 4.4 1.6 4.6 2.6 1.5 14.8 14.5 22.8 12.2 13.0 14.0 13.6 10.9 14.7 14.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type containing 20" Q5W0Z9 13 21372573-21459370 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 7.5 7.0 8.3 9.4 33.6 14.9 11.3 6.4 15.3 10.3 10.9 21.0 7.6 10.8 9.3 5.6 18.4 7.1 10.0 5.4 12.7 11.8 3.8 7.6 10.6 12.3 47.4 4.9 6.5 6.1 4.0 5.3 10.8 26.1 9.2 9.6 3.1 10.4 9.9 5.5 12.2 15.4 8.9 45.0 8.6 23.1 22.0 35.8 10.4 10.0 5.1 10.9 16.2 9.6 4.6 7.8 8.8 15.2 10.1 10.2 11.1 13.5 7.8 11.4 7.2 10.6 11.2 27.9 14.8 14.9 9.9 8.9 14.2 41.5 14.4 8.0 18.1 22.0 13.1 11.4 18.8 15.7 8.3 25.3 4.9 7.8 6.0 17.1 11.0 10.2 8.0 9.8 6.9 15.3 7.0 6.1 14.7 11.4 23.9 6.5 9.3 7.7 19.2 20.5 5.0 11.8 25.2 10.9 5.0 19.5 12.2 8.0 11.2 8.7 26.6 10.5 10.0 17.6 11.0 6.3 7.7 15.0 7.5 9.9 29.5 8.8 15.2 3.4 10.2 14.2 9.4 4.6 8.8 8.7 7.8 3.7 8.3 8.5 2.7 10.1 12.0 3.9 9.3 11.1 8.3 33.6 6.4 15.3 12.7 11.8 47.4 4.9 26.1 35.8 ZDHHC21 "DHHC21, DNZ1, HSPC097" ENSG00000175893 "Zinc finger DHHC-type containing 21" Q8IVQ6 9 14611071-14693471 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065254 Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA065254: " "unprognostic (2.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (2.01e-1)" "unprognostic (4.19e-2)" "unprognostic (2.58e-2)" "unprognostic (2.81e-2)" "unprognostic (1.13e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (9.79e-3)" "unprognostic (3.97e-2)" "prognostic favourable (1.29e-4)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (8.87e-2)" "prognostic favourable (9.28e-6)" 6.5 10.8 15.9 7.9 16.8 4.2 11.6 29.0 22.6 7.8 8.5 9.3 3.8 12.2 9.8 11.7 14.4 7.5 6.7 9.0 13.8 10.4 9.4 4.8 9.2 11.1 9.4 16.5 10.0 8.4 11.5 22.2 7.8 14.8 10.0 9.9 6.6 8.3 7.4 7.7 15.7 12.6 7.7 9.9 9.5 7.9 7.3 9.7 4.7 11.3 9.9 10.7 7.7 11.3 5.2 1.4 0.5 0.8 2.8 1.7 0.6 5.3 2.7 5.4 3.5 0.9 1.0 4.2 6.8 2.1 2.4 2.8 1.3 2.5 5.3 1.7 4.8 3.5 3.7 2.2 3.5 10.6 2.9 22.5 6.0 2.6 2.9 3.9 7.5 1.8 5.2 2.8 1.8 14.2 1.8 0.6 4.3 2.9 0.9 3.8 3.8 5.2 0.0 2.6 2.6 7.6 5.9 3.3 8.9 3.1 3.9 2.1 4.9 6.5 10.1 1.8 2.7 1.7 6.2 2.2 4.1 0.0 3.7 0.2 1.8 0.5 0.4 0.1 1.2 0.8 1.3 5.2 1.2 1.1 0.2 3.5 0.8 1.2 0.0 2.8 0.6 1.4 1.7 0.6 15.9 16.8 29.0 22.6 13.8 10.4 9.4 16.5 14.8 9.7 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type containing 22" Q8N966 14 77131270-77142734 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 52.3" "Group enriched" "Detected in some" 4 "AF22: 5.2;NTERA-2: 5.5;RH-30: 9.2;SCLC-21H: 10.2" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" "Plasma membrane" "HPA049471: , HPA072213: " "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 1.1 1.5 11.2 1.1 12.6 1.1 1.1 8.4 52.3 1.1 1.2 6.7 0.0 1.1 1.1 1.4 1.3 1.2 1.1 1.2 14.5 18.4 1.1 1.1 1.1 1.1 10.7 19.5 1.1 1.1 1.1 3.1 1.1 9.2 1.1 1.3 0.5 1.1 1.1 1.3 1.1 1.1 1.2 3.6 1.1 1.3 1.4 5.1 0.0 1.3 0.0 1.1 1.4 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 5.5 0.7 0.0 9.2 0.0 0.0 0.0 10.2 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 11.2 12.6 8.4 29.5 14.5 18.4 10.7 19.5 9.2 5.1 ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type containing 23" Q8IYP9 3 113947901-113965401 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.7;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm Nucleoplasm "HPA016808: AB_1859002" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (4.48e-3)" "prognostic unfavourable (2.85e-4)" "unprognostic (1.49e-1)" "unprognostic (3.98e-3)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (3.19e-1)" "unprognostic (6.63e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "prognostic favourable (1.48e-7)" "unprognostic (2.58e-2)" "unprognostic (1.83e-1)" "prognostic unfavourable (5.90e-4)" "unprognostic (3.29e-3)" 1.0 0.8 6.3 2.1 5.9 0.4 1.9 2.7 10.4 1.4 7.7 0.9 2.2 6.0 1.5 1.6 1.7 2.1 1.8 1.3 8.9 1.9 4.7 3.2 2.4 2.7 0.9 4.7 1.1 4.4 8.2 3.5 0.4 1.4 1.8 9.9 1.2 4.9 1.4 1.2 2.9 5.4 0.7 0.9 1.9 5.0 25.8 0.6 0.8 5.5 0.9 2.8 1.7 1.5 2.7 1.1 0.5 0.0 0.0 0.5 0.1 13.3 3.4 0.4 7.9 1.2 0.2 11.6 5.3 1.6 1.0 1.6 5.5 9.0 6.1 4.7 3.0 8.8 10.1 1.4 1.7 3.6 4.6 5.7 4.9 3.4 0.4 6.3 5.3 0.2 1.7 0.2 0.7 0.9 0.0 3.6 0.1 7.7 5.2 0.4 2.4 3.8 0.9 4.6 5.1 5.6 6.6 13.9 3.5 4.1 13.7 2.6 8.2 2.1 0.2 3.8 7.7 0.8 2.3 4.1 5.3 9.9 3.3 4.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.1 0.0 1.7 0.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 6.3 5.9 2.7 10.4 8.9 1.9 0.9 4.7 1.4 0.6 ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546238 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavourable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" 11.7 17.4 10.5 10.3 12.8 14.1 12.3 5.7 15.5 7.7 8.3 13.8 10.8 9.1 9.4 17.0 12.2 9.0 11.3 9.9 10.7 11.8 17.3 13.4 11.1 20.4 12.8 10.3 6.5 19.4 22.6 9.6 13.7 9.3 11.4 7.7 10.0 12.4 13.1 7.9 13.2 9.4 7.1 10.0 16.0 12.4 9.9 10.5 11.7 17.7 7.9 13.4 10.0 7.8 5.8 17.2 2.4 5.5 6.6 7.2 4.6 4.8 7.8 2.6 6.7 6.4 5.3 6.5 4.1 3.5 3.3 2.3 6.8 7.9 1.4 11.2 3.5 12.0 1.9 3.6 2.3 7.0 4.9 3.0 3.8 4.2 6.0 3.0 7.5 6.3 6.5 2.7 3.9 5.5 4.3 4.4 4.1 10.6 5.8 8.5 5.1 6.7 7.5 5.4 9.1 4.0 3.9 3.6 5.7 6.6 6.9 11.3 9.5 2.5 8.5 7.6 2.4 8.8 3.0 6.5 2.0 2.0 6.6 1.4 8.2 2.4 5.5 1.0 6.2 4.8 5.7 5.4 5.0 7.2 6.3 5.8 3.0 5.4 2.4 6.6 4.4 17.2 5.1 4.6 10.5 12.8 5.7 15.5 10.7 11.8 12.8 10.3 9.3 10.5 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type containing 3" Q9NYG2 3 44915257-44976185 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favourable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favourable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 23.1 25.8 11.7 17.5 14.0 29.5 39.8 12.5 20.8 17.2 27.9 13.7 17.8 18.4 19.2 17.9 29.1 13.0 22.7 34.6 11.2 9.1 21.7 19.0 20.2 16.1 12.1 7.7 16.5 15.0 16.9 8.8 19.5 19.4 16.1 28.9 14.7 17.4 22.5 20.0 43.0 33.2 15.4 13.6 15.4 20.9 48.0 10.1 14.1 20.4 22.1 20.6 21.4 20.7 5.4 11.4 17.1 10.0 6.0 7.1 5.2 11.9 9.6 8.7 12.1 37.3 18.9 9.7 10.6 13.3 13.6 12.2 11.6 15.8 10.9 5.7 18.7 15.4 13.4 18.7 14.4 10.8 5.7 9.6 13.3 8.5 8.5 25.0 7.9 16.2 23.1 12.9 12.8 14.2 14.1 9.7 12.4 7.7 7.5 18.2 11.6 19.2 5.6 7.3 8.2 13.4 37.6 2.7 10.5 12.7 13.2 5.8 9.9 17.3 15.1 11.8 10.8 13.7 13.8 6.7 12.4 10.8 10.7 38.3 8.7 17.1 10.0 13.8 6.5 5.5 6.1 4.7 4.7 7.1 11.4 5.4 4.9 6.3 11.4 6.0 7.2 6.7 6.9 5.2 11.7 14.0 12.5 20.8 11.2 9.1 12.1 7.7 19.4 10.1 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type containing 4" Q9NPG8 7 6577434-6589374 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032124, HPA064358" Approved Approved "Nuclear bodies" "Nuclear bodies" "HPA032124: AB_10610699, HPA064358: " "unprognostic (1.07e-1)" "prognostic unfavourable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavourable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favourable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (8.94e-4)" 17.7 24.3 20.7 13.5 22.0 11.4 23.6 8.2 29.9 20.7 24.9 22.5 18.2 14.0 21.6 26.9 16.1 25.5 18.8 21.9 17.3 19.7 25.7 34.5 17.0 19.7 19.8 17.7 22.7 46.5 27.2 18.7 14.1 20.4 20.0 16.3 28.0 29.8 22.4 34.9 9.5 16.3 22.7 17.1 13.6 23.5 27.0 12.3 18.1 30.5 17.4 16.5 23.3 13.7 17.6 50.6 20.9 14.9 11.9 15.4 12.6 21.8 13.9 5.2 31.0 28.5 21.5 23.8 12.3 3.1 15.2 18.8 17.3 31.4 13.0 19.6 22.8 20.1 18.2 12.2 15.8 7.7 10.6 14.4 16.6 18.5 25.4 17.1 15.8 22.5 18.1 11.8 0.0 13.5 29.4 19.4 20.9 22.9 9.2 16.7 27.2 12.2 12.6 26.5 19.3 12.0 17.3 12.6 32.1 16.4 6.0 21.5 20.7 22.5 9.0 17.9 26.0 17.1 17.9 28.7 22.9 30.0 10.7 21.4 25.0 20.9 11.7 18.0 11.5 14.9 12.5 17.6 11.6 12.7 13.2 16.1 15.4 14.7 1.3 11.9 10.8 50.6 10.3 12.6 20.7 22.0 8.2 29.9 17.3 19.7 19.8 17.7 20.4 12.3 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type containing 5" Q9C0B5 11 57667747-57701187 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavourable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 19.6 18.2 6.9 14.2 16.1 13.0 17.3 12.4 19.2 20.0 18.7 14.1 20.9 14.6 19.8 15.9 45.8 16.0 19.1 18.2 8.2 8.1 27.8 24.8 18.7 18.0 8.5 8.2 16.2 21.3 31.4 13.9 31.4 12.8 15.5 18.2 19.1 29.3 18.4 31.3 33.2 25.9 15.2 8.7 21.5 16.3 35.7 7.8 26.4 25.5 23.9 39.1 23.3 26.0 9.4 13.4 15.5 11.3 6.9 13.1 9.0 27.9 31.1 12.2 12.4 27.0 20.8 23.0 26.3 31.6 22.1 16.5 18.8 34.5 18.9 34.2 31.1 39.6 19.0 31.2 19.7 23.2 8.6 16.0 14.3 16.7 30.3 30.0 27.2 29.3 28.2 32.6 33.1 24.8 21.1 23.9 27.8 16.8 16.9 8.4 14.8 18.7 16.8 24.7 23.3 25.2 41.6 8.9 11.4 24.5 27.7 25.7 29.7 17.2 29.1 28.6 14.9 30.0 18.3 17.4 21.5 16.3 21.3 15.5 24.8 15.5 8.1 9.8 11.1 10.1 13.1 9.0 10.9 9.4 8.0 9.4 11.0 11.1 10.2 6.9 11.3 13.4 9.8 9.0 6.9 16.1 12.4 19.2 8.2 8.1 8.5 8.2 12.8 7.8 ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type containing 6" Q9H6R6 10 112424428-112446917 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved "HPA014357: AB_2304658" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (6.24e-2)" "unprognostic (5.21e-1)" "unprognostic (3.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (9.30e-2)" "unprognostic (8.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.22e-2)" 17.6 17.7 14.4 21.6 17.2 13.9 17.7 17.5 19.1 16.6 21.3 15.4 25.6 32.2 21.6 25.7 21.1 16.5 17.1 15.1 15.4 13.2 41.7 21.3 17.6 20.3 20.1 15.2 24.5 19.0 15.6 17.6 19.3 19.8 18.6 22.6 18.2 21.4 23.5 13.8 14.8 43.8 16.7 15.5 22.3 18.8 10.7 15.0 20.2 20.5 12.9 21.6 16.7 17.9 16.8 16.4 20.2 17.2 15.5 23.0 15.0 20.3 15.9 16.6 20.6 16.2 12.3 11.8 20.0 19.1 15.8 19.0 15.1 36.5 11.3 9.2 12.1 24.4 13.8 12.8 18.5 26.5 16.9 11.7 18.3 18.7 10.5 26.6 20.6 9.3 8.6 17.3 20.5 19.8 12.6 19.0 17.1 17.1 14.8 29.9 9.7 13.1 12.4 21.1 10.5 18.7 11.3 6.2 8.7 10.3 16.5 18.8 9.2 19.6 14.1 18.3 11.5 12.2 18.8 10.7 12.3 15.0 16.2 47.2 11.8 9.3 17.2 20.2 15.5 15.8 20.1 16.8 17.9 19.5 16.4 13.3 15.2 17.1 11.4 15.5 12.4 13.6 23.0 15.0 14.4 17.2 17.5 19.1 15.4 13.2 20.1 15.2 19.8 15.0 ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type containing 7" Q9NXF8 16 84974181-85011535 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059642" Uncertain Supported "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA019215: , HPA059642: " "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavourable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favourable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" 23.4 20.9 17.7 25.4 14.7 40.3 45.8 17.8 20.0 23.7 26.8 15.5 15.6 19.7 27.7 18.6 20.4 19.2 29.1 24.9 13.0 11.6 23.4 21.3 31.3 36.3 15.5 14.5 21.8 30.0 31.1 15.2 25.1 14.8 24.1 24.3 18.1 18.7 18.4 36.5 23.1 25.5 31.1 14.9 27.1 32.3 18.6 13.9 16.1 19.9 25.8 18.8 27.7 28.9 2.0 6.9 8.5 10.6 1.5 3.0 3.5 20.0 17.7 9.4 11.2 41.6 31.4 12.9 18.6 36.1 29.3 14.6 18.6 23.6 9.2 10.9 30.0 21.2 12.0 24.5 37.0 5.3 9.6 7.2 7.5 21.1 17.4 12.5 7.0 25.9 28.2 23.9 13.8 15.0 21.4 3.2 18.5 24.0 8.5 12.0 14.5 12.9 10.6 8.6 5.0 28.8 26.5 8.0 10.1 24.0 13.5 11.6 25.5 7.6 21.9 17.7 13.5 16.7 10.8 11.1 15.3 20.9 16.8 9.4 14.0 6.7 10.6 8.5 2.5 8.8 3.0 1.6 2.4 2.0 6.9 2.0 1.8 2.6 7.1 1.5 7.2 4.7 0.6 3.5 17.7 14.7 17.8 20.0 13.0 11.6 15.5 14.5 14.8 13.9 ZDHHC8 "KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type containing 8" Q9ULC8 22 20129456-20148007 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavourable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" 20.7 19.2 25.7 16.9 23.0 9.2 23.4 24.4 35.3 14.3 9.9 14.0 17.3 11.6 16.0 10.9 13.9 13.6 14.4 16.0 18.7 10.6 15.2 16.5 14.6 15.4 17.7 17.6 18.0 23.9 17.4 21.0 16.4 19.0 13.4 7.0 17.5 20.4 16.6 20.5 22.2 11.2 13.0 10.4 19.8 15.9 8.4 18.6 8.9 18.5 7.9 11.1 12.9 14.5 2.0 4.1 4.0 1.5 1.3 2.5 0.5 11.3 7.3 11.6 15.3 17.1 10.2 10.5 21.5 14.7 14.6 13.1 3.8 5.9 0.0 8.9 17.8 15.6 6.1 16.4 7.2 16.4 23.3 5.5 19.1 8.7 14.1 0.0 7.7 17.8 11.1 11.2 9.5 16.3 38.0 9.0 12.9 5.6 6.7 14.9 5.9 11.6 14.4 10.2 4.1 6.3 13.9 18.7 9.5 8.7 4.2 10.2 0.3 7.8 18.6 33.2 24.3 18.6 9.5 13.0 4.2 4.3 9.7 7.2 9.7 4.0 1.2 0.3 2.5 1.5 1.3 0.8 0.7 1.2 0.4 2.0 1.3 1.8 0.0 1.3 0.8 4.1 2.0 0.5 25.7 23.0 24.4 35.3 18.7 10.6 17.7 17.6 19.0 18.6 ZDHHC9 "CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type containing 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavourable (9.77e-5)" "prognostic unfavourable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavourable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 18.2 7.3 16.7 6.7 24.7 3.2 14.2 7.8 33.9 14.1 14.7 78.3 5.1 21.1 8.4 8.4 9.8 7.9 10.4 7.4 24.1 15.2 25.4 27.0 15.6 3.0 24.9 13.9 8.0 17.4 19.6 7.1 11.5 28.4 13.4 17.3 3.8 13.2 8.3 7.4 19.7 22.2 10.4 32.7 2.4 12.8 2.8 25.3 1.2 9.6 5.7 4.3 10.8 9.4 4.6 7.8 2.6 6.8 3.4 7.6 3.3 15.2 8.0 11.5 23.2 39.9 31.4 9.4 15.1 17.3 7.2 9.1 12.6 19.9 0.5 25.8 16.0 10.3 13.0 15.1 10.5 0.8 8.1 3.0 8.4 16.6 15.8 2.0 5.5 34.1 24.7 11.8 17.6 13.6 3.3 6.1 11.7 13.3 2.9 3.8 6.2 13.9 2.7 7.4 9.0 10.5 8.5 9.1 7.7 4.3 22.3 7.0 9.5 3.4 11.1 7.4 2.5 17.3 12.1 5.7 4.1 1.8 13.3 8.4 3.7 0.0 3.3 2.6 4.8 2.9 6.1 4.6 5.8 4.7 3.7 2.7 7.6 4.3 0.0 3.4 6.8 7.8 2.5 3.3 16.7 24.7 7.8 33.9 24.1 15.2 24.9 13.9 28.4 25.3 ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein" Q96JP5 11 58579111-58621042 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA024037, CAB025417" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB025417: , HPA024037: AB_1859051" "unprognostic (6.10e-2)" "unprognostic (5.01e-2)" "unprognostic (3.33e-3)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (2.33e-2)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (3.16e-1)" "unprognostic (1.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (2.23e-1)" "unprognostic (2.00e-3)" 17.1 14.7 20.1 13.6 25.6 32.0 14.9 24.4 21.7 15.3 18.1 23.2 15.8 16.2 16.3 11.8 16.3 13.6 13.8 26.5 20.3 15.4 16.3 19.4 15.0 14.4 20.8 18.1 14.9 14.3 26.7 17.0 14.2 19.7 13.1 21.9 11.2 14.5 15.5 33.8 17.5 19.6 16.9 21.6 15.0 13.9 71.0 19.4 15.7 16.8 14.6 15.9 17.8 21.4 4.6 7.0 5.4 5.0 3.7 5.4 2.8 24.5 14.1 16.6 16.8 15.9 19.3 9.1 20.3 38.2 23.6 20.2 7.7 26.0 29.4 20.1 25.6 21.9 16.8 21.6 31.1 15.6 9.4 19.4 14.4 8.3 18.1 24.4 32.0 16.8 21.2 33.1 38.8 23.3 19.2 27.9 30.3 8.2 21.1 13.5 8.7 13.8 16.4 28.0 19.5 17.3 23.7 17.8 14.2 25.9 23.9 33.1 26.6 18.4 26.1 29.8 20.6 44.8 22.5 16.2 11.9 24.5 26.3 13.8 30.3 3.9 5.0 3.5 5.4 4.5 3.0 4.5 3.3 3.3 4.9 4.6 3.6 4.6 5.4 3.7 4.2 7.0 2.6 2.8 20.1 25.6 24.4 21.7 20.3 15.4 20.8 18.1 19.7 19.4 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999030-75110994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.1" "Cell line enhanced" "Detected in many" "HMC-1: 53.8;MOLT-4: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.5;T-reg: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;monocytes: 1.4;T-cells: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favourable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 10.0 9.5 13.4 8.1 13.7 5.2 16.6 6.3 16.5 13.2 12.5 8.1 6.7 8.3 10.7 9.1 28.2 10.0 11.3 9.1 11.6 14.6 5.6 12.8 12.8 8.7 9.1 9.4 10.1 6.1 12.2 6.2 9.7 7.8 9.1 10.8 7.2 7.5 7.5 58.6 14.5 11.2 10.1 8.8 2.8 11.8 21.6 4.9 80.1 21.4 16.9 13.3 14.0 15.5 0.2 0.8 4.5 1.4 0.0 5.2 0.3 3.1 4.6 8.0 8.2 8.6 6.7 27.7 3.8 5.4 5.3 5.2 7.4 9.9 0.8 3.0 8.3 7.6 3.9 5.3 4.2 7.7 2.2 16.5 1.5 13.6 6.8 7.9 53.8 6.0 4.4 5.5 4.5 8.6 7.9 2.6 4.1 30.2 38.5 29.1 11.1 5.0 17.1 3.0 5.0 7.5 9.0 10.7 11.5 6.1 8.1 2.2 21.5 7.5 5.8 3.7 6.4 6.5 2.3 15.4 15.6 9.1 4.8 8.8 3.7 4.5 1.4 0.9 0.2 1.1 1.3 0.2 1.5 0.2 0.8 0.0 0.0 0.2 1.2 0.0 1.1 0.0 5.2 0.3 13.4 13.7 6.3 16.5 11.6 14.6 9.1 9.4 7.8 4.9 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284307-30367692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 5.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved "HPA072244: " "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavourable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favourable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favourable (8.71e-4)" "unprognostic (8.67e-2)" 7.8 8.0 10.0 9.3 10.6 9.7 16.2 12.8 10.0 5.8 16.1 10.5 7.6 11.3 7.7 9.7 14.2 5.2 8.7 8.4 9.6 6.1 19.3 24.0 7.9 12.0 10.0 7.4 5.8 14.0 8.0 9.9 9.6 11.0 7.0 14.3 5.8 10.5 13.7 17.5 11.5 12.7 8.3 10.5 9.2 12.4 20.6 9.1 7.9 13.3 9.8 10.9 9.4 11.8 1.3 5.8 1.4 1.1 0.7 2.4 0.5 6.6 2.4 2.0 1.7 2.3 1.6 10.5 2.5 2.6 2.8 3.9 1.2 11.2 7.0 6.7 2.0 6.5 6.6 4.3 3.1 6.8 6.0 4.3 5.2 3.2 1.2 3.3 8.3 2.5 7.4 1.9 4.8 2.3 5.3 14.0 3.0 2.5 6.8 8.9 4.6 3.0 5.9 4.3 11.9 8.6 14.4 6.9 6.5 5.1 21.7 4.3 5.8 13.6 2.6 2.8 4.8 2.6 5.3 24.0 20.5 9.1 3.0 7.3 4.0 0.5 0.9 1.1 1.0 0.9 1.5 1.3 1.2 1.4 0.8 0.8 0.7 1.1 1.4 0.7 1.1 5.8 2.4 0.5 10.0 10.6 12.8 10.0 9.6 6.1 10.0 7.4 11.0 9.1 ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883592-29057487 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 28.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)" 4.6 11.8 16.8 2.5 14.7 1.0 4.5 12.2 18.1 7.8 5.7 7.7 21.8 5.1 8.3 22.2 5.9 8.1 3.8 4.3 22.0 5.0 13.6 7.5 8.7 1.2 6.1 17.7 10.0 5.4 16.3 4.2 8.0 8.1 12.0 5.9 4.9 12.1 13.4 5.6 7.6 4.7 7.8 8.9 2.2 6.4 6.7 10.5 0.0 6.9 1.9 1.5 5.7 4.9 0.2 0.4 1.5 1.0 2.0 0.5 0.1 3.6 8.7 8.1 2.3 1.5 1.8 15.5 2.2 1.1 1.8 1.7 13.1 2.0 0.0 3.5 1.1 6.2 5.6 3.5 2.2 4.8 5.7 1.4 1.5 28.6 1.3 4.3 1.5 1.8 3.3 2.8 2.8 1.5 3.1 2.1 2.5 3.5 0.1 2.2 3.0 3.5 4.3 5.3 3.3 7.5 5.4 13.5 5.0 4.0 3.9 2.3 2.6 1.9 1.4 6.8 5.8 5.3 3.6 2.8 3.8 5.1 2.9 2.4 3.5 1.0 0.2 1.3 0.2 1.0 0.4 0.1 0.2 0.1 0.4 0.2 0.1 0.5 1.5 2.0 0.2 0.3 0.1 0.1 16.8 14.7 12.2 18.1 22.0 5.0 6.1 17.7 8.1 10.5 ZNRF4 "RNF204, spzn, Ssrzf1" ENSG00000105428 "Zinc and ring finger 4" Q8WWF5 19 5455431-5456856 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 243 "testis: 90.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827835-186849208 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.4" "Cell line enhanced" "Detected in some" "HSkMC: 1.1;U-138 MG: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "unprognostic (2.00e-1)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.1 0.4 0.0 0.0 0.3 0.0