Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"
ACAP2	"CENTB2, CNT-B2, KIAA0041"	ENSG00000114331	"ArfGAP with coiled-coil, ankyrin repeat and PH domains 2"	Q15057	3	195274736-195443078	"Plasma proteins, Predicted intracellular proteins"		"GTPase activation"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"neutrophil: 59.4"	"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034807, HPA034808"	Supported		Approved	Endosomes			9300	Endosomes		"HPA034807: AB_10669896, HPA034808: AB_10673103"	"unprognostic (9.13e-2)"	"unprognostic (1.75e-3)"	"unprognostic (7.05e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.90e-2)"	"unprognostic (5.64e-2)"	"unprognostic (3.08e-3)"	"unprognostic (7.17e-2)"	"unprognostic (3.18e-2)"	"unprognostic (1.57e-1)"	"unprognostic (5.49e-2)"	"unprognostic (2.36e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.58e-1)"	"unprognostic (3.77e-2)"	"unprognostic (8.54e-2)"	25.8	11.7	16.3	26.8	14.4	35.7	19.1	27.0	15.1	22.2	19.4	13.1	12.1	14.3	18.2	13.6	28.3	14.8	14.8	11.5	14.1	11.8	14.2	14.3	18.2	25.8	13.9	11.4	20.9	11.8	16.6	24.2	15.7	16.1	14.5	17.6	15.3	16.7	16.9	10.6	21.1	18.6	15.2	15.3	32.9	13.9	14.9	13.5	30.6	22.2	16.1	27.0	17.4	20.6	12.5	9.2	59.4	15.7	4.5	7.7	5.9	14.7	5.6	9.3	9.2	15.5	19.3	14.0	12.2	16.6	9.2	9.5	8.0	8.6	16.2	29.8	11.2	9.4	7.0	6.0	13.4	18.5	4.3	16.4	6.2	3.3	15.4	22.6	12.0	15.0	10.2	9.1	20.5	9.9	8.0	16.7	13.1	8.5	14.1	8.2	5.7	8.1	16.8	11.3	11.9	6.4	13.7	10.4	5.1	13.2	12.1	14.4	22.7	13.3	17.4	11.6	6.6	15.2	14.1	9.8	20.8	36.9	8.7	23.9	12.2	13.1	15.7	14.3	7.7	13.3	6.1	10.1	7.5	6.0	8.7	12.5	6.3	6.4	59.4	4.5	15.1	9.2	6.6	5.9	16.3	14.4	27.0	14.2	14.1	11.8	13.9	11.4	16.1	13.5
ANKFY1	"ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14"	ENSG00000185722	"Ankyrin repeat and FYVE domain containing 1"	Q9P2R3	17	4163907-4263977	"Plasma proteins, Predicted intracellular proteins"	Endocytosis			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA024513, HPA024522, HPA065849"	Approved		Enhanced	Endosomes			5600	Endosomes		"HPA024513: AB_1844830, HPA024522: AB_10601453, HPA065849: "	"unprognostic (4.57e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.26e-1)"	"unprognostic (9.07e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.42e-3)"	"unprognostic (1.13e-1)"	"unprognostic (7.77e-2)"	"unprognostic (1.08e-1)"	"unprognostic (4.14e-2)"	"unprognostic (7.83e-2)"	"unprognostic (2.55e-2)"	"unprognostic (4.76e-3)"	"unprognostic (2.11e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.05e-1)"	14.7	19.3	16.5	15.6	21.9	15.8	14.1	20.1	25.6	15.9	25.2	33.7	9.4	12.4	27.0	12.3	15.3	17.5	13.3	11.3	19.6	14.2	13.0	15.3	16.7	13.9	21.3	17.2	23.3	13.7	27.1	16.4	15.4	23.2	14.1	15.8	16.0	16.2	14.5	15.3	21.6	15.0	16.6	20.7	16.1	14.7	12.2	26.6	15.4	16.1	8.4	16.5	17.6	15.4	1.6	3.8	2.3	9.7	1.3	4.0	2.6	11.1	25.7	17.8	11.9	24.1	18.4	11.5	12.4	13.1	20.3	20.1	11.4	7.6	9.7	10.2	18.7	17.6	16.2	13.2	17.8	5.1	16.6	9.5	18.4	10.6	13.4	5.6	11.5	19.2	14.0	14.4	10.7	11.8	9.1	9.4	13.7	8.6	8.4	6.1	7.5	9.1	12.8	11.8	5.3	10.5	15.1	6.0	9.3	17.9	8.4	11.0	9.7	7.4	15.0	12.7	6.7	17.4	16.4	3.1	2.4	3.3	15.6	11.6	15.2	1.6	5.0	2.2	4.0	9.7	3.8	1.3	2.6	2.9	3.8	1.6	2.7	2.6	2.3	1.3	9.3	1.5	2.6	2.6	16.5	21.9	20.1	24.7	19.6	14.2	21.3	17.2	23.2	26.6
CLTA	Lca	ENSG00000122705	"Clathrin light chain A"	P09496	9	36190856-36304781	"Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002665, HPA050918, HPA054667"	Enhanced		Enhanced	Vesicles,Endosomes,Lysosomes			2100000	"Vesicles, Endosomes, Lysosomes"		"CAB002665: , HPA050918: , HPA054667: "	"prognostic favourable (5.64e-4)"	"unprognostic (7.62e-2)"	"unprognostic (9.22e-2)"	"unprognostic (8.45e-3)"	"unprognostic (1.71e-1)"	"unprognostic (1.92e-1)"	"prognostic unfavourable (9.46e-5)"	"unprognostic (1.42e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.92e-3)"	"unprognostic (7.27e-2)"	"unprognostic (2.15e-1)"	"unprognostic (1.23e-3)"	"unprognostic (5.92e-2)"	"unprognostic (1.56e-1)"	"prognostic favourable (1.01e-4)"	"unprognostic (4.98e-2)"	60.0	64.8	65.0	46.9	60.8	35.4	55.5	68.6	86.3	58.1	71.4	55.5	35.8	65.6	58.1	64.5	63.8	65.2	56.4	31.4	62.6	62.0	72.2	60.0	48.7	53.1	67.1	67.0	78.1	52.8	42.8	47.0	78.2	67.9	53.3	67.6	48.1	58.8	47.6	33.2	47.5	58.3	52.4	71.5	59.6	56.3	48.3	41.9	58.2	77.1	49.4	54.5	46.2	60.5	31.3	57.3	29.1	59.5	22.6	40.5	45.9	60.3	48.5	36.6	27.8	53.5	53.9	59.0	62.7	47.8	50.5	59.5	36.3	27.2	45.7	34.8	41.7	25.8	45.8	43.6	46.5	30.9	37.0	35.0	49.4	37.1	71.9	37.1	32.5	59.2	48.4	57.9	46.0	62.3	30.4	24.1	76.0	21.0	33.3	47.3	58.4	69.5	32.2	24.3	25.9	68.2	43.3	28.4	47.8	26.2	30.8	51.5	27.8	45.9	79.6	40.8	45.9	46.6	65.2	16.2	38.0	48.5	50.3	52.2	35.9	29.1	56.6	28.0	26.5	59.5	27.8	31.3	28.9	27.2	57.3	30.6	26.4	22.8	22.2	22.6	45.6	49.5	40.5	45.9	65.0	60.8	68.6	86.3	62.6	62.0	67.1	67.0	67.9	41.9
CLTC	"CLTCL2, Hc"	ENSG00000141367	"Clathrin heavy chain"	Q00610	17	59619689-59696956	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Autophagy, Cell cycle, Cell division, Mitosis"		"Cancer-related genes, Disease mutation, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"											"CAB010389, CAB011571, CAB017155, HPA059143"	Approved		Enhanced	"Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol"			51000000	"Vesicles, Endosomes, Lysosomes"	"Mitotic spindle, Cytosol"	"CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: "	"unprognostic (1.56e-1)"	"prognostic unfavourable (7.35e-4)"	"prognostic favourable (7.65e-4)"	"unprognostic (1.03e-1)"	"unprognostic (2.62e-1)"	"unprognostic (5.23e-3)"	"prognostic unfavourable (5.54e-4)"	"unprognostic (1.11e-1)"	"unprognostic (6.43e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.34e-2)"	"unprognostic (2.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.22e-2)"	"unprognostic (1.10e-1)"	"prognostic unfavourable (2.02e-4)"	39.5	45.7	47.4	35.1	57.6	30.7	57.9	59.1	83.6	38.1	45.0	25.1	47.7	27.9	38.7	52.3	32.1	30.9	34.1	39.9	47.1	53.7	48.6	46.0	46.5	60.7	53.9	59.3	29.8	23.3	96.1	30.0	51.5	57.0	38.9	48.9	22.7	28.6	54.4	44.2	30.5	27.7	45.8	47.8	28.0	34.2	29.4	28.8	28.0	43.7	26.6	31.2	37.1	40.6	10.0	24.6	13.9	24.6	12.3	15.6	13.1	46.9	71.1	35.1	34.7	59.3	48.3	40.1	50.5	53.3	45.3	47.3	43.5	28.9	32.7	58.0	71.7	31.0	52.2	42.0	60.5	35.1	28.1	53.6	45.0	67.5	45.2	36.6	31.0	45.7	25.7	68.8	44.4	50.0	53.3	46.3	70.5	83.7	21.7	10.9	30.2	41.5	19.3	58.8	39.6	50.7	66.7	31.5	37.5	31.3	20.5	29.9	48.7	23.1	63.9	83.1	49.6	39.6	51.7	36.5	51.2	30.2	60.9	24.8	50.7	10.5	20.9	13.9	12.7	24.6	15.6	10.0	11.7	13.7	24.6	9.1	10.0	11.0	13.4	12.3	20.7	16.1	14.5	13.1	47.4	57.6	59.1	83.6	47.1	53.7	53.9	59.3	57.0	28.8
GRN	"CLN11, PCDGF, PGRN"	ENSG00000030582	"Granulin precursor"	P28799	17	44345086-44353102	"Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"		Cytokine	"Neurodegeneration, Neuronal ceroid lipofuscinosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	7	"classical monocyte: 138.4;intermediate monocyte: 80.4;myeloid DC: 109.8;neutrophil: 61.8;non-classical monocyte: 36.4;plasmacytoid DC: 95.5"	"Group enriched"	"Detected in all"	8	"dendritic cells: 109.8;granulocytes: 61.8;monocytes: 138.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008763, CAB019394, HPA028747"	Uncertain		Enhanced	"Endoplasmic reticulum,Endosomes,Lysosomes"	"Secreted to blood"		91000000	"Endoplasmic reticulum, Endosomes, Lysosomes"		"CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767"	"unprognostic (1.84e-1)"	"unprognostic (2.34e-1)"	"unprognostic (8.38e-3)"	"unprognostic (2.82e-1)"	"prognostic unfavourable (8.78e-4)"	"unprognostic (7.41e-2)"	"unprognostic (3.53e-3)"	"unprognostic (3.57e-1)"	"unprognostic (1.63e-1)"	"unprognostic (2.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (1.52e-1)"	"unprognostic (6.34e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.43e-1)"	"unprognostic (1.43e-1)"	"unprognostic (1.62e-1)"	66.8	27.1	8.2	31.2	10.2	76.4	30.1	5.2	13.9	29.1	45.0	16.6	46.2	23.2	29.8	76.5	104.7	18.8	51.4	46.9	7.8	9.5	39.3	43.2	74.9	81.1	10.5	9.3	20.7	21.6	11.6	18.0	116.4	11.4	28.7	25.1	23.8	54.5	42.1	15.2	37.3	42.9	21.1	13.4	76.3	25.6	21.0	9.7	23.5	31.4	46.3	52.1	34.8	38.5	13.0	109.8	61.8	138.4	2.1	3.8	83.8	17.2	28.2	8.6	23.2	70.5	37.1	26.4	21.2	67.6	35.0	46.5	12.2	42.6	51.1	45.5	34.2	26.9	12.3	49.5	15.8	8.4	26.6	5.4	14.8	25.7	35.8	8.8	72.0	49.1	65.7	29.1	19.2	39.8	10.4	7.7	23.7	25.6	5.0	25.4	6.5	47.7	14.3	26.9	60.1	39.1	20.6	8.2	10.9	28.4	13.4	52.3	30.6	33.4	47.7	65.6	15.8	44.8	14.6	17.0	46.4	17.4	39.6	20.9	18.1	12.5	138.4	11.9	2.7	80.4	2.1	13.0	2.9	2.4	109.8	8.2	2.2	2.1	61.8	2.1	36.4	95.5	3.8	83.8	8.2	10.2	5.2	13.9	7.8	9.5	10.5	9.3	11.4	9.7
HGS	"Hrs, Vps27, ZFYVE8"	ENSG00000185359	"Hepatocyte growth factor-regulated tyrosine kinase substrate"	O14964	17	81683326-81703138	"Plasma proteins, Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			"HPA004872, HPA007728"	Uncertain		Enhanced	Endosomes,Lysosomes,Cytosol			250000	"Endosomes, Lysosomes"	Cytosol	"HPA004872: AB_1079053, HPA007728: AB_1850681"	"unprognostic (6.52e-2)"	"prognostic unfavourable (4.22e-4)"	"unprognostic (4.29e-1)"	"unprognostic (1.31e-2)"	"unprognostic (4.91e-2)"	"unprognostic (1.04e-1)"	"prognostic unfavourable (5.61e-5)"	"unprognostic (5.54e-3)"	"unprognostic (1.09e-1)"	"unprognostic (9.27e-2)"	"unprognostic (5.30e-2)"	"unprognostic (1.27e-1)"	"prognostic unfavourable (4.31e-7)"	"unprognostic (3.69e-1)"	"unprognostic (2.27e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.45e-1)"	26.8	33.5	34.7	31.9	44.7	66.5	28.9	35.7	45.6	25.4	31.1	35.2	24.5	33.2	27.3	37.2	42.1	32.8	29.1	25.4	32.7	30.4	34.2	31.3	29.4	34.3	39.8	44.2	33.2	39.7	21.8	31.7	32.4	40.7	31.9	31.1	23.6	38.2	27.9	36.3	57.5	32.5	32.6	28.5	38.5	35.6	53.1	38.1	22.2	26.2	25.9	32.5	24.9	34.6	12.2	14.6	28.9	20.2	17.2	18.7	18.8	33.2	27.1	20.5	25.4	18.5	20.9	22.5	25.0	24.3	29.3	22.6	22.8	23.8	9.3	17.1	33.8	28.3	17.3	27.4	20.7	7.9	28.9	20.0	34.1	28.7	27.9	17.2	26.4	23.3	30.0	32.7	46.6	36.7	21.8	17.1	30.8	20.1	18.9	39.8	14.8	28.8	20.6	16.4	14.7	28.7	25.2	29.3	34.9	19.0	48.4	22.2	29.7	33.4	30.5	57.1	33.6	28.2	46.4	21.9	7.7	11.8	35.1	22.5	30.0	25.2	17.4	22.3	18.7	20.2	12.4	11.4	13.5	13.0	14.6	12.2	10.1	11.7	28.9	17.2	19.1	12.4	14.9	18.8	34.7	44.7	35.7	45.6	32.7	30.4	39.8	44.2	40.7	38.1
RAB5C	"RAB5CL, RABL"	ENSG00000108774	"RAB5C, member RAS oncogene family"	P51148	17	42124976-42155044	"Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003426, HPA004167"	Approved		Enhanced	Endosomes			3600000	Endosomes		"HPA003426: AB_1079735, HPA004167: "	"unprognostic (1.41e-1)"	"unprognostic (6.02e-2)"	"unprognostic (6.75e-3)"	"unprognostic (3.69e-1)"	"unprognostic (2.48e-1)"	"prognostic unfavourable (7.08e-4)"	"unprognostic (1.56e-3)"	"unprognostic (4.85e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.52e-2)"	"unprognostic (2.79e-1)"	"unprognostic (2.98e-2)"	"unprognostic (6.06e-3)"	"unprognostic (4.37e-1)"	"unprognostic (2.32e-1)"	"unprognostic (2.82e-2)"	"unprognostic (1.12e-2)"	50.4	47.8	40.8	43.6	49.4	69.6	43.8	27.9	68.8	33.8	41.9	53.0	25.8	53.6	41.9	28.5	36.4	35.6	36.0	26.2	38.5	34.3	70.3	63.6	46.0	44.5	46.5	32.5	34.9	30.5	28.4	20.1	42.1	41.4	29.8	35.1	37.3	33.1	36.6	16.8	33.8	49.7	39.1	40.4	50.0	44.4	25.2	42.2	29.8	53.5	21.0	36.8	38.7	31.7	13.9	23.8	56.9	31.4	14.8	15.9	21.8	28.7	54.3	17.0	24.5	38.0	26.3	32.9	35.4	37.5	49.1	42.9	38.3	28.5	14.0	31.3	43.8	40.5	31.2	34.2	31.5	18.0	40.9	21.3	22.2	55.2	37.4	27.9	35.0	33.8	36.1	36.8	25.8	51.1	24.3	21.7	33.1	26.3	28.3	25.0	16.8	0.1	18.6	29.3	23.7	36.9	43.2	9.5	24.3	18.1	115.1	38.0	50.8	27.4	47.9	50.2	28.0	42.1	37.5	20.2	26.1	17.8	33.1	21.9	50.8	13.6	31.4	34.8	14.1	29.7	12.6	12.7	13.8	14.1	23.8	13.9	11.4	11.3	56.9	14.8	29.7	16.0	15.9	21.8	40.8	49.4	27.9	68.8	38.5	34.3	46.5	32.5	41.4	42.2
RPS6KC1	humS6PKh1	ENSG00000136643	"Ribosomal protein S6 kinase C1"	Q96S38	1	213051233-213274773	"Enzymes, Predicted intracellular proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA026531, HPA031565"	Approved		Enhanced	Endosomes,Lysosomes				"Endosomes, Lysosomes"		"HPA026531: AB_10601497, HPA031565: "	"unprognostic (3.90e-2)"	"unprognostic (5.90e-2)"	"unprognostic (3.22e-1)"	"unprognostic (4.88e-2)"	"unprognostic (2.42e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.32e-2)"	"unprognostic (1.64e-1)"	"unprognostic (4.10e-2)"	"unprognostic (3.34e-1)"	"unprognostic (4.18e-1)"	"unprognostic (5.11e-2)"	"prognostic unfavourable (2.70e-4)"	"unprognostic (8.10e-2)"	"unprognostic (5.48e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.44e-2)"	12.0	14.1	15.6	10.0	19.4	6.4	17.1	13.5	19.4	14.1	13.1	12.6	8.8	9.2	15.9	8.4	10.3	11.8	11.6	9.4	17.3	15.6	9.8	10.8	13.6	7.5	17.8	16.8	14.4	13.5	19.9	16.7	12.3	15.3	17.6	10.1	7.3	8.9	17.7	14.1	6.7	8.7	18.5	22.3	11.0	12.5	26.5	13.2	6.8	10.4	6.1	7.8	14.6	16.0	2.5	8.7	13.7	6.8	4.0	3.3	2.2	7.4	6.4	10.6	11.4	10.6	15.7	9.3	9.8	14.4	15.2	17.5	5.2	8.3	4.7	6.6	14.7	6.1	12.8	8.0	11.6	9.9	4.7	12.7	7.6	7.2	9.8	8.0	15.1	10.3	6.9	13.3	7.3	12.6	16.3	7.3	15.5	4.0	3.3	2.6	15.3	7.3	4.0	10.0	4.6	7.0	7.5	6.2	16.1	10.6	8.4	14.0	12.0	3.4	11.7	10.4	9.6	11.9	6.4	4.3	8.3	3.6	4.4	3.1	10.6	13.7	4.6	3.3	2.8	6.8	2.3	2.5	2.3	2.4	8.7	1.9	1.5	3.3	0.5	4.0	6.3	1.0	1.6	2.2	15.6	19.4	13.5	19.0	17.3	15.6	17.8	16.8	15.3	13.2
SLC12A4	KCC1	ENSG00000124067	"Solute carrier family 12 member 4"	Q9UP95	16	67943474-67969601	"FDA approved drug targets, Predicted membrane proteins, Transporters"	"Ion transport, Potassium transport, Symport, Transport"		"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA041138	Approved		Approved	Endosomes				Endosomes		"HPA041138: AB_10794544"	"unprognostic (5.07e-2)"	"unprognostic (6.18e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.68e-2)"	"unprognostic (9.28e-2)"	"unprognostic (1.48e-2)"	"unprognostic (4.28e-2)"	"unprognostic (3.26e-3)"	"unprognostic (9.58e-2)"	"unprognostic (1.55e-1)"	"unprognostic (2.01e-2)"	"unprognostic (1.81e-2)"	"prognostic favourable (2.25e-6)"	"unprognostic (6.42e-2)"	"unprognostic (1.42e-1)"	"unprognostic (7.64e-2)"	"unprognostic (2.26e-1)"	16.6	18.3	9.2	8.0	8.8	3.1	26.5	7.0	12.7	19.4	16.5	20.1	12.0	5.1	20.7	9.7	11.8	13.8	15.5	24.4	12.2	5.2	10.7	17.1	19.5	6.6	11.4	8.2	14.2	11.9	30.1	8.1	32.6	18.1	17.8	4.3	23.0	10.5	20.7	14.6	16.9	8.6	27.4	10.0	10.2	10.9	17.6	9.8	8.8	21.0	9.1	8.4	16.5	16.6	1.0	2.4	8.3	5.4	2.7	1.6	1.6	5.0	6.8	5.2	9.9	17.4	15.3	28.3	15.4	16.0	13.3	11.6	13.5	8.1	1.7	7.6	21.3	9.2	2.4	19.1	10.1	1.8	2.0	1.3	8.8	14.7	19.8	0.1	6.3	16.9	12.5	17.9	6.5	8.2	4.0	1.5	18.2	0.7	1.9	5.0	3.9	3.6	2.0	9.9	1.6	7.3	4.4	0.0	3.2	29.4	1.8	2.6	14.0	2.0	11.1	19.0	13.5	8.4	6.6	9.2	2.3	3.0	11.1	1.4	16.4	8.3	3.9	2.0	1.5	5.4	1.0	0.4	0.9	0.9	2.4	1.0	0.8	0.7	1.4	2.7	3.8	1.1	1.6	1.6	9.2	8.8	7.0	8.6	12.2	5.2	11.4	8.2	18.1	9.8
SNX1	"HsT17379, MGC8664, SNX1A, Vps5"	ENSG00000028528	"Sorting nexin 1"	Q13596	15	64094123-64146090	"Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA047373, HPA052761"	Approved		Enhanced	Endosomes,Lysosomes				"Endosomes, Lysosomes"		"HPA047373: AB_2680018, HPA052761: AB_2681939"	"unprognostic (3.99e-2)"	"unprognostic (8.65e-3)"	"unprognostic (1.96e-1)"	"unprognostic (1.50e-2)"	"unprognostic (7.13e-2)"	"unprognostic (2.73e-1)"	"unprognostic (7.15e-2)"	"unprognostic (6.49e-3)"	"unprognostic (1.53e-1)"	"unprognostic (8.28e-2)"	"unprognostic (2.47e-2)"	"unprognostic (3.26e-1)"	"prognostic favourable (9.88e-6)"	"unprognostic (2.27e-1)"	"unprognostic (3.98e-1)"	"unprognostic (2.59e-2)"	"unprognostic (1.95e-1)"	30.6	47.3	22.4	27.4	31.2	16.8	36.3	17.7	25.3	32.4	30.3	46.9	44.7	26.0	30.8	39.2	38.7	21.2	23.5	30.9	24.8	20.1	30.6	38.6	33.7	31.3	40.1	23.5	25.0	31.2	43.0	22.2	31.1	30.3	31.0	27.1	22.5	30.8	48.4	40.9	29.1	26.3	30.4	54.1	37.5	30.2	17.7	35.9	32.9	80.8	18.5	35.9	32.3	31.7	34.5	42.3	51.9	50.6	30.7	30.6	43.9	19.0	25.4	22.0	18.7	39.0	29.2	7.1	26.3	31.1	28.1	33.2	17.2	34.7	22.9	27.1	27.6	29.9	34.8	31.5	23.5	37.0	15.4	26.3	29.9	24.7	21.3	26.5	30.1	32.9	20.3	21.9	17.1	28.9	20.8	9.0	29.0	28.4	28.2	22.5	14.9	15.0	25.6	20.3	32.2	43.3	45.9	17.8	17.0	23.4	18.0	22.8	25.8	24.6	28.7	24.5	33.1	15.6	15.1	23.9	60.4	32.4	19.6	36.4	25.3	41.5	50.6	51.9	29.7	47.2	25.0	32.0	25.4	28.9	42.3	34.5	24.7	24.0	38.1	30.7	43.5	28.4	30.6	43.9	22.4	31.2	17.7	25.3	24.8	20.1	40.1	23.5	30.3	35.9
SNX2		ENSG00000205302	"Sorting nexin 2"	O60749	5	122774996-122830108	"Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA037400	Approved		Supported	Endosomes,Lysosomes			39000000	"Endosomes, Lysosomes"		"HPA037400: AB_10670381"	"unprognostic (9.26e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.91e-1)"	"prognostic unfavourable (7.90e-6)"	"unprognostic (1.03e-1)"	"unprognostic (3.86e-2)"	"unprognostic (3.27e-2)"	"unprognostic (4.41e-2)"	"unprognostic (1.60e-1)"	"prognostic favourable (8.76e-7)"	"unprognostic (8.76e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.07e-1)"	"unprognostic (8.59e-2)"	32.1	28.0	27.7	36.0	27.7	22.1	52.1	30.4	24.7	22.0	24.1	14.1	34.0	20.4	24.7	36.6	25.3	24.9	22.0	33.3	27.2	17.4	38.5	30.1	39.5	58.9	27.2	23.2	33.1	26.2	24.7	29.8	34.7	26.0	23.3	24.5	12.4	27.7	29.7	20.9	23.4	27.4	35.8	27.7	45.8	27.0	14.5	28.1	16.0	40.4	21.2	34.6	30.3	30.4	84.6	34.5	30.5	43.5	9.6	16.5	32.1	16.3	13.1	17.3	13.5	39.2	23.9	73.4	13.3	20.7	15.6	22.8	22.9	23.8	21.1	32.9	15.2	5.6	36.3	24.2	23.2	20.8	21.7	21.4	13.0	15.6	26.4	9.3	16.0	22.4	18.6	16.3	23.5	17.1	10.9	15.6	16.7	14.8	7.7	12.5	10.8	15.5	33.3	17.3	23.7	23.3	26.7	13.9	10.5	15.5	18.0	21.5	22.7	22.5	19.3	13.9	12.5	19.9	15.1	11.7	14.5	23.0	18.4	34.3	16.6	30.5	43.3	26.7	8.7	43.5	10.0	84.6	11.9	10.4	34.5	84.4	11.8	9.9	15.2	9.6	42.7	10.2	16.5	32.1	27.7	27.7	30.4	24.7	27.2	17.4	27.2	23.2	26.0	28.1
SNX6		ENSG00000129515	"Sorting nexin 6"	Q9UNH7	14	34561094-34630183	"Plasma proteins, Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049374	Approved		Supported	Endosomes,Lysosomes				"Endosomes, Lysosomes"		"HPA049374: "	"unprognostic (1.89e-1)"	"unprognostic (6.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (3.06e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.36e-3)"	"prognostic unfavourable (1.25e-4)"	"unprognostic (1.23e-1)"	"unprognostic (6.63e-2)"	"unprognostic (1.06e-1)"	"prognostic unfavourable (4.68e-4)"	"unprognostic (1.91e-1)"	"unprognostic (3.48e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.55e-1)"	"unprognostic (8.82e-2)"	"unprognostic (2.10e-2)"	35.7	27.0	26.7	23.0	23.2	16.3	29.4	19.0	21.5	20.8	28.1	30.7	17.7	37.0	37.9	18.0	24.9	16.3	21.6	19.0	28.3	22.0	30.4	18.6	17.6	33.5	33.7	18.1	20.7	15.5	61.1	19.1	46.2	26.7	22.3	24.3	14.7	20.1	18.6	20.3	18.3	38.4	23.2	50.9	33.6	20.8	23.1	23.3	28.5	21.5	19.6	21.9	28.5	22.5	30.5	29.4	56.0	43.1	29.8	43.9	45.2	31.7	18.0	21.0	13.6	32.7	67.4	29.5	31.4	34.8	32.4	28.4	17.3	39.7	20.6	26.3	41.2	22.5	22.2	23.2	56.7	25.2	8.9	12.4	11.0	31.6	28.1	21.8	15.5	43.3	25.6	22.1	32.2	44.0	13.3	17.1	43.3	18.3	19.6	10.7	11.4	21.6	21.0	24.3	20.8	41.3	24.3	16.5	17.8	25.3	22.0	26.3	28.4	14.2	43.2	23.3	16.6	22.5	20.1	15.8	25.7	23.4	12.7	12.0	25.9	26.7	32.8	39.5	32.3	43.1	41.7	30.5	43.9	37.4	29.4	27.0	33.6	36.0	56.0	29.8	39.7	19.3	42.7	45.2	26.7	23.2	19.0	21.5	28.3	22.0	33.7	18.1	26.7	23.3
TFRC	"CD71, p90, TFR1"	ENSG00000072274	"Transferrin receptor"	P02786	3	196027183-196082189	"Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters"	"Endocytosis, Host-virus interaction"	"Host cell receptor for virus entry, Receptor"	"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"placenta: 110.0"	"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000153, HPA028598"	Enhanced		Supported	Endosomes,Lysosomes	"Secreted to blood"	1310000000	14000000	"Endosomes, Lysosomes"		"CAB000153: AB_2533029, HPA028598: AB_10601599"	"unprognostic (2.95e-2)"	"prognostic unfavourable (3.67e-4)"	"unprognostic (2.55e-1)"	"unprognostic (1.48e-2)"	"unprognostic (6.75e-2)"	"unprognostic (7.88e-3)"	"prognostic unfavourable (1.15e-4)"	"unprognostic (6.92e-2)"	"unprognostic (3.30e-3)"	"unprognostic (4.35e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.14e-2)"	"unprognostic (3.63e-3)"	"unprognostic (3.65e-2)"	"unprognostic (1.19e-2)"	"prognostic unfavourable (2.96e-4)"	"unprognostic (2.62e-2)"	24.3	11.9	11.9	20.6	11.3	73.8	7.6	9.6	17.8	11.8	25.0	9.5	3.8	11.9	12.1	7.5	18.5	11.7	11.4	18.7	9.5	8.3	15.3	13.6	28.1	8.1	7.4	9.5	50.0	7.8	18.0	6.9	110.0	26.5	7.2	19.4	8.5	8.3	5.0	25.6	9.9	37.4	10.9	13.2	7.9	10.0	8.3	6.1	14.3	7.0	10.5	12.9	11.2	8.0	5.7	7.5	2.2	12.4	1.8	6.5	2.1	21.9	20.0	9.2	18.6	20.4	11.8	57.5	31.4	23.9	22.1	36.7	48.7	20.2	22.5	59.6	11.6	33.9	31.5	10.4	27.1	107.6	10.7	85.3	17.0	22.6	16.1	69.9	17.3	13.3	10.3	19.0	17.2	7.3	35.5	21.6	17.2	20.3	22.9	14.8	28.0	41.0	12.2	13.7	27.0	19.8	55.6	21.0	8.7	30.3	79.7	7.1	77.4	14.6	9.4	26.3	21.4	23.0	47.0	6.1	47.5	35.2	30.8	19.0	15.9	0.0	1.6	2.2	2.5	7.9	1.7	5.7	2.7	1.7	3.7	3.2	2.5	1.9	0.3	1.8	12.4	7.5	6.5	2.1	11.9	11.3	9.6	17.8	9.5	8.3	7.4	9.5	26.5	6.1
TMEM106B	"FLJ11273, MGC33727"	ENSG00000106460	"Transmembrane protein 106B"	Q9NUM4	7	12211241-12243367	"Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	Transport		"Amyotrophic lateral sclerosis, Disease mutation, Leukodystrophy, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA058342	Approved		Supported	Endosomes,Lysosomes				"Endosomes, Lysosomes"		"HPA058342: "	"unprognostic (5.29e-2)"	"unprognostic (2.34e-2)"	"unprognostic (4.20e-2)"	"unprognostic (6.20e-2)"	"unprognostic (2.73e-1)"	"unprognostic (1.87e-2)"	"unprognostic (3.50e-2)"	"unprognostic (5.89e-2)"	"unprognostic (4.44e-2)"	"unprognostic (1.30e-1)"	"unprognostic (3.01e-3)"	"unprognostic (2.09e-2)"	"unprognostic (1.75e-3)"	"unprognostic (5.52e-2)"	"unprognostic (3.06e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.70e-1)"	17.1	48.3	16.2	11.4	23.7	6.2	17.0	18.5	29.0	26.0	20.3	19.4	13.5	16.1	24.9	19.7	18.5	19.9	18.0	20.8	15.7	16.2	30.9	33.0	12.9	11.7	20.5	21.2	22.1	18.3	17.5	31.3	35.3	26.8	27.2	22.6	15.2	23.2	24.3	23.9	15.5	18.1	24.8	24.8	13.5	15.5	12.0	21.3	14.7	30.7	14.9	12.4	21.4	17.9	7.6	2.8	8.8	6.3	14.1	19.4	7.3	9.8	23.4	9.5	25.3	22.2	21.6	10.1	14.6	33.4	10.3	13.3	5.7	38.9	3.9	16.5	19.4	11.4	8.2	9.6	14.1	5.7	7.5	4.8	10.9	6.7	17.9	12.7	6.9	17.3	12.4	7.6	18.0	15.8	11.5	11.8	15.4	4.2	2.8	7.2	15.3	9.5	7.1	8.2	7.7	25.5	9.9	12.2	17.3	15.6	14.2	13.4	12.9	9.1	15.6	14.9	18.0	12.8	12.5	10.9	19.7	4.6	18.6	5.2	34.1	8.8	4.2	4.8	9.4	4.9	13.5	6.3	11.6	11.1	2.8	7.6	19.4	13.5	2.5	14.1	6.3	0.9	9.7	7.3	16.2	23.7	18.5	29.0	15.7	16.2	20.5	21.2	26.8	21.3
TMEM192	FLJ38482	ENSG00000170088	"Transmembrane protein 192"	Q8IY95	4	165070608-165208549	"Predicted membrane proteins, Transporters"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA014717, HPA024110"	Enhanced		Supported	Nucleoplasm,Endosomes,Lysosomes				"Endosomes, Lysosomes"	Nucleoplasm	"HPA014717: AB_1844373, HPA024110: AB_2204898"	"prognostic unfavourable (9.52e-4)"	"unprognostic (5.38e-3)"	"unprognostic (9.16e-2)"	"unprognostic (4.39e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.55e-2)"	"unprognostic (2.91e-3)"	"unprognostic (8.43e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.10e-1)"	"unprognostic (3.27e-2)"	"unprognostic (5.06e-2)"	"prognostic favourable (2.33e-14)"	"unprognostic (2.09e-2)"	"unprognostic (1.37e-1)"	"unprognostic (2.76e-2)"	"unprognostic (9.30e-2)"	12.6	14.4	11.3	7.4	13.6	5.3	12.1	12.0	11.9	11.6	9.7	10.5	6.2	8.3	9.7	10.0	7.8	10.1	8.9	10.4	9.9	9.4	40.7	37.7	9.1	8.5	13.0	10.6	21.8	21.3	20.3	14.2	9.3	13.1	19.4	11.7	24.7	11.3	7.8	19.0	7.4	8.2	8.6	13.3	10.8	10.5	8.6	11.3	3.1	22.9	5.2	6.6	12.1	7.3	18.2	12.0	3.4	12.5	13.4	12.8	7.7	6.2	9.5	3.4	8.7	9.0	3.2	8.0	9.5	14.1	10.0	11.2	5.5	10.3	13.8	5.7	6.1	5.6	12.8	9.8	11.6	8.9	6.6	7.6	7.1	6.2	23.0	18.8	10.3	11.6	20.9	8.9	18.3	8.1	13.0	23.2	12.2	13.6	3.2	5.6	7.1	8.1	7.4	3.0	12.5	8.1	9.2	7.3	7.7	14.9	23.7	15.1	11.5	8.7	6.1	4.4	5.4	13.8	10.8	22.8	30.2	19.2	10.6	10.4	17.5	2.0	12.5	3.4	9.7	10.9	12.8	18.2	7.5	9.9	11.6	15.2	8.3	10.0	1.4	13.4	5.8	12.0	6.0	7.7	11.3	13.6	12.0	11.9	9.9	9.4	13.0	10.6	13.1	11.3
VPS26A	"Hbeta58, PEP8A, VPS26"	ENSG00000122958	"VPS26, retromer complex component A"	O75436	10	69123512-69172861	"Plasma proteins, Predicted intracellular proteins"	"Protein transport, Transport"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011602, HPA057498, CAB075733"	Supported		Enhanced	Endosomes,Lysosomes			19000	"Endosomes, Lysosomes"		"CAB011602: AB_2215043, CAB075733: , HPA057498: "	"unprognostic (1.17e-2)"	"unprognostic (6.94e-2)"	"unprognostic (5.58e-2)"	"unprognostic (9.35e-2)"	"unprognostic (5.95e-2)"	"prognostic unfavourable (1.72e-4)"	"prognostic unfavourable (1.70e-6)"	"unprognostic (1.17e-1)"	"unprognostic (1.35e-1)"	"unprognostic (7.88e-2)"	"prognostic unfavourable (9.18e-6)"	"unprognostic (4.63e-2)"	"unprognostic (2.15e-2)"	"unprognostic (7.14e-2)"	"unprognostic (6.68e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.72e-1)"	30.7	25.8	31.8	18.8	37.1	25.2	29.6	42.6	37.2	23.3	27.5	14.5	15.1	21.4	24.5	20.7	37.1	20.7	20.9	40.7	33.3	21.1	34.3	26.5	23.9	17.7	26.5	25.4	24.1	19.3	31.4	24.5	36.4	29.9	23.9	28.8	15.3	25.7	20.3	29.3	33.8	28.0	22.9	35.4	24.7	22.7	34.2	29.1	21.8	27.8	23.6	22.8	30.8	27.3	16.9	28.1	28.2	29.4	34.7	28.1	25.3	33.1	12.7	15.6	28.0	27.6	25.1	13.8	20.3	33.0	24.9	28.4	29.8	32.6	10.3	16.5	22.2	23.0	23.4	20.3	34.6	9.3	12.7	15.5	11.8	16.6	35.7	23.4	12.5	22.7	31.9	24.8	55.3	26.1	29.7	14.7	39.5	10.5	10.5	26.5	10.5	32.3	13.1	25.9	12.4	29.0	19.7	9.6	14.3	27.6	38.1	36.9	15.0	20.1	29.9	16.9	21.7	27.4	26.4	8.8	21.3	16.9	23.2	38.2	8.8	28.2	25.4	22.9	27.9	29.4	25.3	16.9	21.6	28.1	28.1	13.7	19.2	26.6	23.0	34.7	24.2	11.5	24.1	25.3	31.8	37.1	42.6	37.2	33.3	21.1	26.5	25.4	29.9	29.1
VPS35	"FLJ10752, MEM3, PARK17"	ENSG00000069329	"VPS35, retromer complex component"	Q96QK1	16	46656132-46689518	"Disease related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction, Protein transport, Transport"		"Neurodegeneration, Parkinson disease, Parkinsonism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA040802	Supported		Supported	Endosomes,Lysosomes			320000	"Endosomes, Lysosomes"		"HPA040802: "	"unprognostic (1.11e-2)"	"unprognostic (8.70e-2)"	"prognostic favourable (7.74e-4)"	"unprognostic (4.75e-2)"	"unprognostic (1.90e-1)"	"unprognostic (5.67e-3)"	"prognostic unfavourable (2.10e-6)"	"unprognostic (5.32e-2)"	"unprognostic (1.49e-1)"	"unprognostic (2.29e-2)"	"unprognostic (3.33e-3)"	"unprognostic (2.49e-1)"	"prognostic favourable (9.75e-5)"	"unprognostic (3.68e-3)"	"unprognostic (2.43e-1)"	"unprognostic (1.34e-1)"	"unprognostic (6.89e-3)"	14.1	12.6	15.1	11.8	21.1	18.3	15.7	13.1	23.6	14.3	15.2	11.9	10.0	11.7	13.0	19.3	16.4	14.8	11.2	14.0	15.1	18.6	13.4	9.2	14.4	11.6	20.4	17.0	16.2	11.7	22.8	18.0	15.3	31.7	14.5	12.2	8.4	12.3	12.7	11.9	19.5	21.9	12.7	16.5	14.0	12.3	12.1	10.9	14.0	12.2	11.8	13.0	17.1	11.6	2.4	2.9	3.1	9.2	1.7	3.2	2.0	8.5	8.7	10.0	6.3	12.1	16.6	5.4	8.2	10.2	11.7	6.2	8.5	6.0	9.1	8.7	10.0	8.4	10.2	12.3	13.5	2.5	11.6	6.7	4.9	6.5	11.3	9.5	6.7	11.0	13.8	10.1	5.9	11.6	6.4	2.5	12.4	6.1	10.9	9.1	3.0	11.4	11.3	14.3	16.6	11.3	7.2	7.2	8.3	8.1	9.1	7.4	3.8	8.8	11.6	8.9	2.9	9.2	9.7	5.5	5.6	9.3	15.4	12.3	4.9	2.2	2.7	2.6	1.6	4.5	1.7	2.4	1.9	2.1	2.9	2.4	3.2	2.4	3.1	1.7	9.2	1.7	2.7	2.0	15.1	21.1	13.1	23.6	15.1	18.6	20.4	17.0	31.7	10.9