Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"
ADAMTS16	ADAMTS16s	ENSG00000145536	"ADAM metallopeptidase with thrombospondin type 1 motif 16"	Q8TE57	5	5140330-5320304	"Predicted secreted proteins"		"Hydrolase, Metalloprotease, Protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 20.4;ovary: 16.3"	"Cell line enhanced"	"Detected in some"		"hTEC/SVTERT24-B: 6.2;U-2 OS: 4.9;U-2197: 9.1;U-87 MG: 4.7"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"cerebellum: 20.4;cerebral cortex: 5.2"	"Cell type enriched"	"Detected in single"	10	"NK-cell: 3.6"	"Lineage enriched"	"Detected in single"	10	"NK-cells: 3.6"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			HPA067668			Approved	"Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria"	"Secreted to extracellular matrix"			"Nuclear membrane, Mitochondria"	"Nucleoplasm, Midbody ring"	"HPA067668: "	"unprognostic (8.48e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.86e-2)"	"unprognostic (1.98e-4)"	"unprognostic (1.91e-2)"	"unprognostic (5.04e-2)"	"unprognostic (7.64e-2)"	"unprognostic (7.80e-3)"	"unprognostic (2.12e-2)"	"unprognostic (5.44e-2)"	"unprognostic (1.51e-2)"	"unprognostic (2.18e-1)"	"prognostic favourable (3.29e-5)"	"unprognostic (1.20e-4)"	"unprognostic (1.46e-1)"	"unprognostic (4.59e-3)"	"unprognostic (2.86e-3)"	7.4	0.4	1.8	0.5	2.8	0.6	1.0	20.4	5.2	2.6	0.9	0.1	3.7	0.6	2.3	11.0	1.9	1.1	8.8	0.9	1.7	0.5	5.4	0.6	0.9	0.2	0.5	1.9	16.3	6.3	0.0	0.5	0.2	2.2	0.7	0.4	0.0	0.4	0.8	0.5	0.5	0.6	10.4	0.6	0.4	0.6	0.8	0.0	0.0	0.8	0.0	0.1	3.4	1.5	0.2	0.1	0.3	0.0	3.6	0.2	0.0	2.6	2.7	2.7	0.1	0.2	0.6	0.2	0.1	0.1	0.6	0.9	0.1	2.4	0.2	3.3	0.0	0.2	0.0	0.0	0.8	0.1	1.6	0.1	3.9	0.1	0.0	0.3	0.1	0.0	0.0	6.2	0.2	0.0	0.8	0.4	1.2	0.1	0.1	0.3	1.7	2.5	0.5	3.3	0.2	0.1	0.0	1.1	0.1	0.1	0.1	0.2	0.1	0.2	0.1	3.3	4.9	9.1	2.1	0.5	0.2	0.1	4.7	0.1	0.4	0.3	0.0	0.1	0.2	0.0	0.2	0.0	0.2	0.1	0.1	0.2	0.2	0.1	0.3	3.6	0.0	0.0	0.0	0.0	1.8	2.8	20.4	5.2	1.7	0.5	0.5	1.9	2.2	0.0
CCDC66	DKFZp686C0433	ENSG00000180376	"Coiled-coil domain containing 66"	A2RUB6	3	56557161-56621818	"Predicted intracellular proteins"	"Cilium biogenesis/degradation"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"		"Low tissue specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044185, HPA051937"	Approved		Supported	"Cell Junctions,Midbody ring,Centriolar satellite,Cytosol"				"Centriolar satellite"	"Cell Junctions, Midbody ring, Cytosol"	"HPA044185: AB_10965852, HPA051937: "	"unprognostic (2.28e-2)"	"unprognostic (7.74e-2)"	"unprognostic (7.37e-2)"	"unprognostic (2.90e-1)"	"unprognostic (5.28e-2)"	"unprognostic (1.72e-2)"	"unprognostic (7.26e-3)"	"unprognostic (1.68e-3)"	"unprognostic (2.05e-2)"	"unprognostic (1.27e-1)"	"unprognostic (3.05e-3)"	"unprognostic (5.48e-3)"	"unprognostic (6.85e-3)"	"unprognostic (1.81e-1)"	"unprognostic (6.57e-2)"	"unprognostic (3.24e-1)"	"unprognostic (6.81e-3)"	8.4	7.5	9.3	7.6	11.7	6.5	12.0	31.0	15.1	11.7	11.0	9.6	7.6	5.9	12.7	12.7	6.7	12.9	7.6	8.4	9.8	6.4	9.2	4.6	7.7	10.1	10.8	10.6	14.7	7.1	10.1	32.9	7.6	11.0	9.7	9.4	7.8	9.1	10.9	11.9	5.7	7.7	11.1	11.2	8.7	8.0	8.6	12.9	11.9	12.1	5.7	10.2	11.0	9.7	2.6	1.1	7.0	2.2	5.0	14.1	2.7	5.4	1.9	6.1	3.6	9.2	5.4	4.8	7.0	6.4	9.2	8.1	4.2	4.3	15.2	1.6	3.7	3.0	3.4	6.4	10.3	5.4	4.1	9.5	8.4	4.8	6.5	12.1	3.6	5.3	9.3	7.6	5.4	5.8	8.8	2.4	7.1	4.4	9.7	7.7	9.9	7.5	3.3	5.2	8.2	5.5	1.9	2.3	4.2	8.4	5.4	5.1	1.9	5.3	3.1	6.9	5.4	6.4	9.5	4.9	5.2	8.1	5.1	13.9	5.4	7.0	1.5	3.3	4.3	1.9	5.6	2.6	7.4	5.3	1.1	1.7	8.6	6.2	0.3	5.0	2.2	1.0	14.1	2.7	9.3	11.7	31.0	15.1	9.8	6.4	10.8	10.6	11.0	12.9
IL16	"FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16"	ENSG00000172349	"Interleukin 16"	Q14005	15	81159575-81314058	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Chemotaxis, Host-virus interaction, Transcription, Transcription regulation"	Cytokine	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 75.7;lymphoid tissue: 97.9"	"Cell line enhanced"	"Detected in some"		"Daudi: 12.2;HEL: 12.9;HMC-1: 23.3;RPMI-8226: 22.1;U-266/70: 27.7;U-698: 11.4;U-937: 15.5"	"Low cancer specificity"	"Detected in all"			"Region enriched"	"Detected in all"	6	"cerebellum: 40.1"	"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in some"	13	"cerebellum: 61.1;hippocampal formation: 29.7"	"Region enriched"	"Detected in single"	38	"cerebellum: 96.7"	"CAB005247, HPA018467, HPA048861"	Enhanced		Supported	"Nuclear speckles,Plasma membrane,Midbody ring,Cytosol"	"Secreted to blood"	125370	14000	"Nuclear speckles"	"Plasma membrane, Midbody ring, Cytosol"	"CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: "	"unprognostic (8.23e-3)"	"unprognostic (2.70e-3)"	"unprognostic (1.97e-2)"	"unprognostic (9.61e-4)"	"unprognostic (2.01e-1)"	"unprognostic (5.26e-4)"	"unprognostic (2.63e-2)"	"unprognostic (6.72e-3)"	"unprognostic (2.25e-1)"	"unprognostic (3.91e-1)"	"unprognostic (1.47e-1)"	"unprognostic (6.21e-2)"	"unprognostic (3.16e-3)"	"unprognostic (1.21e-1)"	"unprognostic (3.23e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.29e-1)"	8.8	2.4	4.1	48.0	5.8	19.5	7.8	40.1	4.3	4.7	4.8	4.6	0.9	3.8	5.4	2.9	3.4	9.7	5.6	5.1	4.9	2.1	2.5	3.9	14.7	58.0	5.8	2.3	3.7	1.7	0.7	1.4	3.0	6.7	3.5	5.9	3.4	13.5	1.5	1.8	6.1	19.2	3.3	7.8	38.2	5.0	2.2	5.5	97.9	3.7	2.4	54.8	8.7	5.4	43.3	37.1	75.7	35.0	49.3	60.5	66.5	0.0	0.0	0.0	0.0	8.2	3.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.2	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	12.9	0.0	0.0	0.4	9.1	23.3	0.4	0.0	0.0	0.2	0.1	1.3	4.9	0.0	0.0	0.7	9.7	0.0	0.0	0.0	0.0	22.1	0.0	0.0	0.0	0.0	0.0	0.0	4.4	0.0	2.0	0.1	0.1	0.1	0.4	0.0	27.7	2.3	11.4	0.8	15.5	0.7	52.7	27.4	75.7	43.1	35.0	48.6	43.3	45.1	47.1	37.1	39.9	60.5	48.6	69.1	49.3	33.7	28.0	47.0	66.5	4.1	5.8	40.1	4.3	4.9	2.1	5.8	2.3	6.7	5.5
MICAL3	KIAA0819	ENSG00000243156	"Microtubule associated monooxygenase, calponin and LIM domain containing 3"	Q7RTP6	22	17787649-18024559	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell cycle, Cell division, Exocytosis"	"Actin-binding, Monooxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"WM-115: 50.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	5	"basophil: 10.0;memory B-cell: 3.3;naive B-cell: 5.2"	"Group enriched"	"Detected in many"	6	"B-cells: 5.2;granulocytes: 10.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000639, HPA003421, HPA034882"	Approved		Supported	"Nucleoplasm,Plasma membrane,Midbody ring,Cytosol"				"Nucleoplasm, Midbody ring"	"Plasma membrane, Cytosol"	"HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: "	"unprognostic (1.65e-1)"	"unprognostic (1.02e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.00e-2)"	"unprognostic (7.68e-2)"	"unprognostic (2.06e-1)"	"unprognostic (4.71e-2)"	"unprognostic (3.07e-3)"	"unprognostic (3.41e-1)"	"unprognostic (1.01e-1)"	"unprognostic (4.58e-1)"	"unprognostic (3.82e-1)"	"unprognostic (8.86e-3)"	"unprognostic (1.36e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.03e-2)"	"unprognostic (6.64e-2)"	10.1	9.0	15.4	20.7	19.2	10.2	9.6	62.2	25.0	12.8	22.4	30.0	8.8	8.3	30.3	14.0	13.8	28.6	9.5	23.7	15.4	13.8	8.7	16.8	6.1	15.2	21.6	15.6	20.2	10.2	30.4	11.0	11.9	19.4	11.8	16.5	14.2	8.0	14.8	28.0	14.7	13.2	26.1	20.9	12.2	11.1	15.7	22.6	3.0	10.4	7.8	20.8	14.7	15.1	5.2	0.3	10.0	0.1	1.3	1.1	0.2	13.7	15.1	8.0	13.0	6.0	7.8	9.7	12.1	13.2	17.2	13.6	14.4	1.9	15.4	6.2	16.5	15.9	11.8	14.0	16.7	14.9	11.2	16.0	16.1	6.0	4.0	7.1	8.6	6.3	11.2	18.1	19.2	10.0	17.5	9.9	6.3	12.3	6.7	4.4	5.5	9.9	9.4	12.0	0.7	13.8	9.7	21.2	8.3	17.1	10.9	25.8	4.3	3.0	17.6	17.7	11.4	12.1	25.2	6.5	11.5	20.6	15.4	3.2	50.7	10.0	0.0	0.1	0.5	0.1	0.8	3.3	0.6	0.5	0.1	5.2	0.3	0.2	0.2	1.3	0.0	0.3	1.1	0.2	15.4	19.2	62.2	25.0	15.4	13.8	21.6	15.6	19.4	22.6