Our cells contain tiny molecular clocks that control a multitude of physiological and behavioral processes according to the circadian rhythm. Governed by a central clock, residing in the suprachiasmic nucleus of the brain, peripheral clocks are present in almost all tissues and organs (Hastings et al., 2003). They are, though able to persist in the absence of environmental cues, driven by the 24-hour patterns of light and temperature produced by the earth´s rotation, and periodically regulate functions such as body temperature, blood pressure, circulating hormones and metabolism (Mazzoccoli et al., 2012)...Read more

Tripartite motif-containing protein 73 (gene: TRIM73) is a protein whose expression at the protein level was unveiled only recently by a team affiliated with the Human Protein Atlas. Multiplex immunohistochemistry allowed them to confirm its cell-type specific localization in the ovary, thus significantly advancing our understanding of both TRIM73 and the ovary proteome...Read more

The postdoc Emma Gerrits in Jan Mulders HPA related research group at KI has recently, as the youngest person ever, received a 1.2 MSEK grant from Alzheimerfonden for research on the development of Frontotemporal dementia (FTD)...Read more

Here we want to draw some attention to one of the rather unknown but interesting genes that we have encountered, the TMEM253 gene specifically expressed in the intestine...Read more