News Articles

A new study describes the neuropeptide landscape of prefrontal cortex in the human brain


In a study published today in the US-based journal PNAS, insights regarding the chemical anatomy of the human prefrontal cortex are described. In particular, a wide spectrum of peptidergic systems is explored that may finetune/modulate functions that are executed in this part of the brain during health and disease. The project was conducted by an international team with researchers from Karolinska Institutet (Sweden), SciLifeLab, KTH-Royal Institute of Technology, Linköping University, the Human Brain Tissue Bank (Hungary) and McGill University (Canada)...Read more

A human adipose tissue cell-type transcriptome atlas


Adipose tissue acts as an energy depot, provides insulation, and is an important endocrine organ that communicates with other tissues to regulate systemic metabolism...Read more

The pig single cell landscape identifies heterogeneity of endothelial cells


The pig single cell landscape identifies heterogeneity of endothelial cells across major organs and tissues...Read more

Dynamics of the normal gut microbiota


The human gut hosts a dynamic microbial ecosystem: the gut microbiota, which has an extensive metabolic repertoire and is increasingly recognized to influence host metabolism and overall physiology...Read more

A novel technology platform based on DNA nanoball arrays (Stereo-seq)


In a publication in Cell, a novel spatiotemporal analytic package is described in which the gene expression can be studied at a subcellular level using a technology platform based on nanoballs distributed on an array with single cell resolution. The platform combines high spatial sensitivity with large field of view, and the publication reports its use to generate a spatially resolved transcriptomic atlas of mouse organogenesis. The study is an international collaboration with researchers from China, USA and Europe, including the Swedish universities KTH-Royal Institute of Technology and Karolinska Institutet at SciLifeLab in Stockholm...Read more