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Citing the Human Protein AtlasTo cite us, please use:
The Human Protein Atlas
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Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F.
Tissue-based map of the human proteome.
Science 2015 347(6220):1260419.
PubMed: 25613900 DOI: 10.1126/science.1260419
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The Blood Atlas
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Uhlen M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P.
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Science. 2019 366(6472)
PubMed: 31857451 DOI: 10.1126/science.aax9198
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The Brain Atlas
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Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Science 2020 367(6482)
DOI: 10.1126/science.aay5947
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The Human Secretome
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Uhlén M, Karlsson MJ, Hober A, Svensson AS, Scheffel J, Kotol D, Zhong W, Tebani A, Strandberg L, Edfors F, Sjöstedt E, Mulder J, Mardinoglu A, Berling A, Ekblad S, Dannemeyer M, Kanje S, Rockberg J, Lundqvist M, Malm M, Volk AL, Nilsson P, Månberg A, Dodig-Crnkovic T, Pin E, Zwahlen M, Oksvold P, von Feilitzen K, Häussler RS, Hong MG, Lindskog C, Ponten F, Katona B, Vuu J, Lindström E, Nielsen J, Robinson J, Ayoglu B, Mahdessian D, Sullivan D, Thul P, Danielsson F, Stadler C, Lundberg E, Bergström G, Gummesson A, Voldborg BG, Tegel H, Hober S, Forsström B, Schwenk JM, Fagerberg L, Sivertsson Å.
The human secretome.
Sci Signal. 2019 12(609)
PubMed: 31772123 DOI: 10.1126/scisignal.aaz0274
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The Cell Atlas
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Thul PJ, Åkesson L, Wiking M, Mahdessian D, Geladaki A, Ait Blal H, Alm T, Asplund A, Björk L, Breckels LM, Bäckström A, Danielsson F, Fagerberg L, Fall J, Gatto L, Gnann C, Hober S, Hjelmare M, Johansson F, Lee S, Lindskog C, Mulder J, Mulvey CM, Nilsson P, Oksvold P, Rockberg J, Schutten R, Schwenk JM, Sivertsson Å, Sjöstedt E, Skogs M, Stadler C, Sullivan DP, Tegel H, Winsnes C, Zhang C, Zwahlen M, Mardinoglu A, Pontén F, von Feilitzen K, Lilley KS, Uhlén M, Lundberg E.
A subcellular map of the human proteome.
Science. 2017 356(6340): eaal3321
PubMed: 28495876 DOI: 10.1126/science.aal3321 Free access:
Abstract,
Full text,
Reprint
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The Pathology Atlas
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Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, Benfeitas R, Arif M, Liu Z, Edfors F, Sanli K, von Feilitzen K, Oksvold P, Lundberg E, Hober S, Nilsson P, Mattsson J, Schwenk JM, Brunnström H, Glimelius B, Sjöblom T, Edqvist PH, Djureinovic D, Micke P, Lindskog C, Mardinoglu A, Ponten F.
A pathology atlas of the human cancer transcriptome.
Science. 2017 357(6352)
PubMed: 28818916 DOI: 10.1126/science.aan2507
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The original Human Protein Atlas publication
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Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
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Publications
| 559 |
Tebani A, Gummesson A, Zhong W, Koistinen IS, Lakshmikanth T, Olsson LM, Boulund F, Neiman M, Stenlund H, Hellström C, Karlsson MJ, Arif M, Dodig-Crnković T, Mardinoglu A, Lee S, Zhang C, Chen Y, Olin A, Mikes J, Danielsson H, Feilitzen KV, Jansson PA, Angerås O, Huss M, Kjellqvist S, Odeberg J, Edfors F, Tremaroli V, Forsström B, Schwenk JM, Nilsson PN, Moritz TM, Bäckhed F, Engstrand L, Brodin P, Bergström G, Uhlén M and Fagerberg L
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Under review. 2020 -
|
| 558 |
Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Science 2020 367(6482)
DOI: 10.1126/science.aay5947
|
| 557 |
Uhlen M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P.
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Science. 2019 366(6472)
PubMed: 31857451 DOI: 10.1126/science.aax9198
|
| 556 |
Uhlén M, Karlsson MJ, Hober A, Svensson AS, Scheffel J, Kotol D, Zhong W, Tebani A, Strandberg L, Edfors F, Sjöstedt E, Mulder J, Mardinoglu A, Berling A, Ekblad S, Dannemeyer M, Kanje S, Rockberg J, Lundqvist M, Malm M, Volk AL, Nilsson P, Månberg A, Dodig-Crnkovic T, Pin E, Zwahlen M, Oksvold P, von Feilitzen K, Häussler RS, Hong MG, Lindskog C, Ponten F, Katona B, Vuu J, Lindström E, Nielsen J, Robinson J, Ayoglu B, Mahdessian D, Sullivan D, Thul P, Danielsson F, Stadler C, Lundberg E, Bergström G, Gummesson A, Voldborg BG, Tegel H, Hober S, Forsström B, Schwenk JM, Fagerberg L, Sivertsson Å.
The human secretome.
Sci Signal. 2019 12(609)
PubMed: 31772123 DOI: 10.1126/scisignal.aaz0274 Free access:
Abstract,
Full text,
Reprint
|
| 555 |
Koivula RW, Forgie IM, Kurbasic A, Viñuela A, Heggie A, Giordano GN, Hansen TH, Hudson M, Koopman ADM, Rutters F, Siloaho M, Allin KH, Brage S, Brorsson CA, Dawed AY, De Masi F, Groves CJ, Kokkola T, Mahajan A, Perry MH, Rauh SP, Ridderstråle M, Teare HJA, Thomas EL, Tura A, Vestergaard H, White T, Adamski J, Bell JD, Beulens JW, Brunak S, Dermitzakis ET, Froguel P, Frost G, Gupta R, Hansen T, Hattersley A, Jablonka B, Kaye J, Laakso M, McDonald TJ, Pedersen O, Schwenk JM, Pavo I, Mari A, McCarthy MI, Ruetten H, Walker M, Pearson E, Franks PW, IMI DIRECT Consortium.
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.
Diabetologia. 2019 62(9):1601-1615.
PubMed: 31203377 DOI: 10.1007/s00125-019-4906-1
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| 554 |
Elfving H, Mattsson JSM, Lindskog C, Backman M, Menzel U, Micke P.
Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray.
Clin Lung Cancer. 2019 20(4):258-262.e1.
PubMed: 30926355 DOI: 10.1016/j.cllc.2019.02.012
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| 553 |
Pineau C, Hikmet F, Zhang C, Oksvold P, Chen S, Fagerberg L, Uhlén M, Lindskog C.
Cell Type-Specific Expression of Testis Elevated Genes Based on Transcriptomics and Antibody-Based Proteomics.
J Proteome Res. 2019 Epub ahead of print
PubMed: 31429579 DOI: 10.1021/acs.jproteome.9b00351
|
| 552 |
Pin E, Sjöberg R, Andersson E, Hellström C, Olofsson J, Jernbom Falk A, Bergström S, Remnestål J, Just D, Nilsson P, Månberg A.
Array-Based Profiling of Proteins and Autoantibody Repertoires in CSF.
Methods Mol Biol. 2019 2044():303-318.
PubMed: 31432421 DOI: 10.1007/978-1-4939-9706-0_19
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| 551 |
Tengvall K, Huang J, Hellström C, Kammer P, Biström M, Ayoglu B, Lima Bomfim I, Stridh P, Butt J, Brenner N, Michel A, Lundberg K, Padyukov L, Lundberg IE, Svenungsson E, Ernberg I, Olafsson S, Dilthey AT, Hillert J, Alfredsson L, Sundström P, Nilsson P, Waterboer T, Olsson T, Kockum I.
Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.
Proc Natl Acad Sci U S A. 2019 116(34):16955-16960.
PubMed: 31375628 DOI: 10.1073/pnas.1902623116
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| 550 |
Idborg H, Zandian A, Ossipova E, Wigren E, Preger C, Mobarrez F, Checa A, Sohrabian A, Pucholt P, Sandling JK, Fernandes-Cerqueira C, Rönnelid J, Oke V, Grosso G, Kvarnström M, Larsson A, Wheelock CE, Syvänen AC, Rönnblom L, Kultima K, Persson H, Gräslund S, Gunnarsson I, Nilsson P, Svenungsson E, Jakobsson PJ.
Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
Front Immunol. 2019 10():1029.
PubMed: 31156624 DOI: 10.3389/fimmu.2019.01029
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| 549 |
Bedri SK, Nilsson OB, Fink K, Månberg A, Hamsten C, Ayoglu B, Manouchehrinia A, Nilsson P, Olsson T, Hillert J, Grönlund H, Glaser A.
Plasma protein profiling reveals candidate biomarkers for multiple sclerosis treatment.
PLoS One. 2019 14(5):e0217208.
PubMed: 31141529 DOI: 10.1371/journal.pone.0217208
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| 548 |
Neiman M, Hellström C, Just D, Mattsson C, Fagerberg L, Schuppe-Koistinen I, Gummesson A, Bergström G, Kallioniemi O, Achour A, Sallinen R, Uhlén M, Nilsson P.
Individual and stable autoantibody repertoires in healthy individuals.
Autoimmunity. 2019 52(1):1-11.
PubMed: 30835561 DOI: 10.1080/08916934.2019.1581774
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| 547 |
Idborg H, Zandian A, Sandberg AS, Nilsson B, Elvin K, Truedsson L, Sohrabian A, Rönnelid J, Mo J, Grosso G, Kvarnström M, Gunnarsson I, Lehtiö J, Nilsson P, Svenungsson E, Jakobsson PJ.
Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjögren's syndrome differ in molecular signatures and treatment perspectives.
Arthritis Res Ther. 2019 21(1):62.
PubMed: 30777133 DOI: 10.1186/s13075-019-1836-8
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| 546 |
Mikus M, Johansson C, Acevedo N, Nilsson P, Scheynius A.
The antimicrobial protein S100A12 identified as a potential autoantigen in a subgroup of atopic dermatitis patients.
Clin Transl Allergy. 2019 9():6.
PubMed: 30728947 DOI: 10.1186/s13601-019-0240-4
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| 545 |
Khoonsari PE, Shevchenko G, Herman S, Remnestål J, Giedraitis V, Brundin R, Degerman Gunnarsson M, Kilander L, Zetterberg H, Nilsson P, Lannfelt L, Ingelsson M, Kultima K.
Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers.
J Alzheimers Dis. 2019 67(2):639-651.
PubMed: 30614806 DOI: 10.3233/JAD-180855
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| 544 |
Ge C, Xu B, Liang B, Lönnblom E, Lundström SL, Zubarev RA, Ayoglu B, Nilsson P, Skogh T, Kastbom A, Malmström V, Klareskog L, Toes REM, Rispens T, Dobritzsch D, Holmdahl R.
Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol. 2019 71(2):210-221.
PubMed: 30152126 DOI: 10.1002/art.40698
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| 543 |
Steen J, Forsström B, Sahlström P, Odowd V, Israelsson L, Krishnamurthy A, Badreh S, Mathsson Alm L, Compson J, Ramsköld D, Ndlovu W, Rapecki S, Hansson M, Titcombe PJ, Bang H, Mueller DL, Catrina AI, Grönwall C, Skriner K, Nilsson P, Lightwood D, Klareskog L, Malmström V.
Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell-Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis.
Arthritis Rheumatol. 2019 71(2):196-209.
PubMed: 30152202 DOI: 10.1002/art.40699
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| 542 |
Månberg A, Bradley F, Qundos U, Guthrie BL, Birse K, Noël-Romas L, Lindskog C, Bosire R, Kiarie J, Farquhar C, Burgener AD, Nilsson P, Broliden K.
A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection.
Mol Cell Proteomics. 2019 18(3):461-476.
PubMed: 30504243 DOI: 10.1074/mcp.RA118.000757
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| 541 |
Lundberg E, Borner GHH.
Spatial proteomics: a powerful discovery tool for cell biology.
Nat Rev Mol Cell Biol. 2019 20(5):285-302.
PubMed: 30659282 DOI: 10.1038/s41580-018-0094-y
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| 540 |
Edlund K, Madjar K, Mattsson JSM, Djureinovic D, Lindskog C, Brunnström H, Koyi H, Brandén E, Jirström K, Pontén F, Rahnenführer J, Micke P, Hengstler JG.
Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC.
J Thorac Oncol. 2019 14(4):628-640.
PubMed: 30639618 DOI: 10.1016/j.jtho.2018.12.022
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| 539 |
Cadenas C, Vosbeck S, Edlund K, Grgas K, Madjar K, Hellwig B, Adawy A, Glotzbach A, Stewart JD, Lesjak MS, Franckenstein D, Claus M, Hayen H, Schriewer A, Gianmoena K, Thaler S, Schmidt M, Micke P, Pontén F, Mardinoglu A, Zhang C, Käfferlein HU, Watzl C, Frank S, Rahnenführer J, Marchan R, Hengstler JG.
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Int J Cancer. 2019 145(4):901-915.
PubMed: 30653260 DOI: 10.1002/ijc.32138
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| 538 |
Wang D, Eraslan B, Wieland T, Hallström B, Hopf T, Zolg DP, Zecha J, Asplund A, Li LH, Meng C, Frejno M, Schmidt T, Schnatbaum K, Wilhelm M, Ponten F, Uhlen M, Gagneur J, Hahne H, Kuster B.
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues.
Mol Syst Biol. 2019 15(2):e8503.
PubMed: 30777892 DOI: 10.15252/msb.20188503
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| 537 |
Eraslan B, Wang D, Gusic M, Prokisch H, Hallström BM, Uhlén M, Asplund A, Pontén F, Wieland T, Hopf T, Hahne H, Kuster B, Gagneur J.
Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.
Mol Syst Biol. 2019 15(2):e8513.
PubMed: 30777893 DOI: 10.15252/msb.20188513
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| 536 |
Aasebø KØ, Dragomir A, Sundström M, Mezheyeuski A, Edqvist PH, Eide GE, Ponten F, Pfeiffer P, Glimelius B, Sorbye H.
Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients.
Cancer Med. 2019 8(7):3623-3635.
PubMed: 31070306 DOI: 10.1002/cam4.2205
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| 535 |
Mezheyeuski A, Hrynchyk I, Herrera M, Karlberg M, Osterman E, Ragnhammar P, Edler D, Portyanko A, Ponten F, Sjöblom T, Glimelius B, Östman A.
Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer.
Br J Cancer. 2019 121(4):303-311.
PubMed: 31289351 DOI: 10.1038/s41416-019-0519-1
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| 534 |
Niinivirta M, Enblad G, Lindskog C, Pontén F, Dragomir A, Ullenhag GJ.
Tumoral Pyruvate Kinase L/R as a Predictive Marker for the Treatment of Renal Cancer Patients with Sunitinib and Sorafenib.
J Cancer. 2019 10(14):3224-3231.
PubMed: 31289593 DOI: 10.7150/jca.30130
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| 533 |
Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Deutsch EW.
Progress on Identifying and Characterizing the Human Proteome: 2018-2019 Metrics from the HUPO Human Proteome Project.
J Proteome Res. 2019 Epub ahead of print
PubMed: 31430157 DOI: 10.1021/acs.jproteome.9b00434
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| 532 |
Häussler RS, Bendes A, Iglesias M, Sanchez-Rivera L, Dodig-Crnković T, Byström S, Fredolini C, Birgersson E, Dale M, Edfors F, Fagerberg L, Rockberg J, Tegel H, Uhlén M, Qundos U, Schwenk JM.
Systematic Development of Sandwich Immunoassays for the Plasma Secretome.
Proteomics. 2019 19(15):e1900008.
PubMed: 31278833 DOI: 10.1002/pmic.201900008
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| 531 |
Fredolini C, Byström S, Sanchez-Rivera L, Ioannou M, Tamburro D, Pontén F, Branca RM, Nilsson P, Lehtiö J, Schwenk JM.
Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles.
Sci Rep. 2019 9(1):8324.
PubMed: 31171813 DOI: 10.1038/s41598-019-43552-5
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| 530 |
Edfors F, Forsström B, Vunk H, Kotol D, Fredolini C, Maddalo G, Svensson AS, Bostrom T, Tegel H, Nilsson P, Schwenk JM, Uhlén M.
Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics.
J Proteome Res. 2019 Epub ahead of print
PubMed: 31094526 DOI: 10.1021/acs.jproteome.8b00924
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| 529 |
Pernemalm M, Sandberg A, Zhu Y, Boekel J, Tamburro D, Schwenk JM, Björk A, Wahren-Herlenius M, Åmark H, Östenson CG, Westgren M, Lehtiö J.
In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta.
Elife. 2019 8():.
PubMed: 30958262 DOI: 10.7554/eLife.41608
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| 528 |
Andersson A, Remnestål J, Nellgård B, Vunk H, Kotol D, Edfors F, Uhlén M, Schwenk JM, Ilag LL, Zetterberg H, Blennow K, Månberg A, Nilsson P, Fredolini C.
Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease.
Clin Chim Acta. 2019 494():79-93.
PubMed: 30858094 DOI: 10.1016/j.cca.2019.03.243
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| 527 |
Drobin K, Assadi G, Hong MG, Andersson E, Fredolini C, Forsström B, Reznichenko A, Akhter T, Ek WE, Bonfiglio F, Hansen MB, Sandberg K, Greco D, Repsilber D, Schwenk JM, D'Amato M, Halfvarson J.
Targeted Analysis of Serum Proteins Encoded at Known Inflammatory Bowel Disease Risk Loci.
Inflamm Bowel Dis. 2019 25(2):306-316.
PubMed: 30358838 DOI: 10.1093/ibd/izy326
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| 526 |
Nicholson AM, Olpe C, Hoyle A, Thorsen AS, Rus T, Colombé M, Brunton-Sim R, Kemp R, Marks K, Quirke P, Malhotra S, Ten Hoopen R, Ibrahim A, Lindskog C, Myers MB, Parsons B, Tavaré S, Wilkinson M, Morrissey E, Winton DJ.
Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.
Cell Stem Cell. 2018 22(6):909-918.e8.
PubMed: 29779891 DOI: 10.1016/j.stem.2018.04.020
|
| 525 |
Morin E, Sjöberg E, Tjomsland V, Testini C, Lindskog C, Franklin O, Sund M, Öhlund D, Kiflemariam S, Sjöblom T, Claesson-Welsh L.
VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival.
J Pathol. 2018 246(3):311-322.
PubMed: 30027561 DOI: 10.1002/path.5141
|
| 524 |
Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnström H, Lindskog C, Elfving H, Micke P, Saito A, Nagase T.
An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.
J Thorac Oncol. 2018 13(11):1676-1691.
PubMed: 30121393 DOI: 10.1016/j.jtho.2018.07.096
|
| 523 |
Strakova K, Kowalski-Jahn M, Gybel T, Valnohova J, Dhople VM, Harnos J, Bernatik O, Ganji RS, Zdrahal Z, Mulder J, Lindskog C, Bryja V, Schulte G.
Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization.
J Biol Chem. 2018 293(48):18477-18493.
PubMed: 30309985 DOI: 10.1074/jbc.RA118.004656
|
| 522 |
Guo J, Grow EJ, Mlcochova H, Maher GJ, Lindskog C, Nie X, Guo Y, Takei Y, Yun J, Cai L, Kim R, Carrell DT, Goriely A, Hotaling JM, Cairns BR.
The adult human testis transcriptional cell atlas.
Cell Res. 2018 28(12):1141-1157.
PubMed: 30315278 DOI: 10.1038/s41422-018-0099-2
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| 521 |
Reuterswärd P, Bergström S, Orikiiriza J, Lindquist E, Bergström S, Andersson Svahn H, Ayoglu B, Uhlén M, Wahlgren M, Normark J, Ribacke U, Nilsson P.
Levels of human proteins in plasma associated with acute paediatric malaria.
Malar J. 2018 17(1):426.
PubMed: 30442134 DOI: 10.1186/s12936-018-2576-y
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| 520 |
Quintana MDP, Ch'ng JH, Zandian A, Imam M, Hultenby K, Theisen M, Nilsson P, Qundos U, Moll K, Chan S, Wahlgren M.
SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion.
PLoS One. 2018 13(8):e0201669.
PubMed: 30092030 DOI: 10.1371/journal.pone.0201669
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| 519 |
Frostegård J, Hellström C, Nilsson P, Frostegård AG, Ajeganova S.
Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus.
Lupus. 2018 27(10):1670-1678.
PubMed: 30041579 DOI: 10.1177/0961203318788153
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| 518 |
Sjöberg R, Andersson E, Hellström C, Mattsson C, Schwenk JM, Nilsson P, Ayoglu B.
High-Density Antigen Microarrays for the Assessment of Antibody Selectivity and Off-Target Binding.
Methods Mol Biol. 2018 1785():231-238.
PubMed: 29714022 DOI: 10.1007/978-1-4939-7841-0_15
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| 517 |
Ayoglu B, Nilsson P, Schwenk JM.
Multiplexed Antigen Bead Arrays for the Assessment of Antibody Selectivity and Epitope Mapping.
Methods Mol Biol. 2018 1785():239-248.
PubMed: 29714023 DOI: 10.1007/978-1-4939-7841-0_16
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Fredholm H, Magnusson K, Lindström LS, Tobin NP, Lindman H, Bergh J, Holmberg L, Pontén F, Frisell J, Fredriksson I.
Breast cancer in young women and prognosis: How important are proliferation markers?
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Mod Pathol. 2017 Epub ahead of print
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A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours.
Acta Neuropathol. 2017 Epub ahead of print
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Carapito C, Duek P, Macron C, Seffals M, Rondel K, Delalande F, Lindskog C, Fréour T, Vandenbrouck Y, Lane L, Pineau C.
Validating Missing Proteins in Human Sperm Cells by Targeted Mass-Spectrometry- and Antibody-based Methods.
J Proteome Res. 2017 Epub ahead of print
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Protein Sci. 2017 Epub ahead of print
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Guo J, Grow EJ, Yi C, Mlcochova H, Maher GJ, Lindskog C, Murphy PJ, Wike CL, Carrell DT, Goriely A, Hotaling JM, Cairns BR.
Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development.
Cell Stem Cell. 2017 21(4):533-546.e6.
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Bosley J, Boren C, Lee S, Grøtli M, Nielsen J, Uhlen M, Boren J, Mardinoglu A.
Improving the economics of NASH/NAFLD treatment through the use of systems biology.
Drug Discov Today. 2017 22(10):1532-1538.
PubMed: 28736156 DOI: 10.1016/j.drudis.2017.07.005
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Hepatology. 2017 66(4):1357-1358.
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The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.
Sci Rep. 2017 7(1):9273.
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Mol Syst Biol. 2017 13(8):938.
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Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Cell Metab. 2017 26(2):281-283.
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New Challenges to Study Heterogeneity in Cancer Redox Metabolism.
Front Cell Dev Biol. 2017 5():65.
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AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion.
Arterioscler Thromb Vasc Biol. 2017 37(4):609-610.
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Mol Syst Biol. 2017 13(3):916.
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The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays.
J Proteome Res. 2017 Epub ahead of print
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Transl Psychiatry. 2017 7(7):e1177.
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Transl Oncol. 2017 10(3):385-395.
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A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer.
J Immunother. 2017 Epub ahead of print
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Sci Rep. 2017 7(1):137.
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Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
J Proteome Res. 2017 16(3):1300-1314.
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Mol Syst Biol. 2016 12(10):883.
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The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
Sci Transl Med. 2016 8(369):369ra177.
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PLoS One. 2016 11(12):e0167909.
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Editorial: The Impact of Systems Medicine on Human Health and Disease.
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mSystems. 2016 1(6):.
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ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer.
BMC Cancer. 2016 16(1):904.
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Endocrinology. 2016 ():en20161758.
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An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter.
J Cereb Blood Flow Metab. 2016 Epub ahead of print
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Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain.
J Alzheimers Dis. 2016 54(4):1671-1686.
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Behav Brain Res. 2016 Epub ahead of print
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PLoS One. 2016 11(3):e0150672.
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Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.
Cell Metab. 2016 23(1):10-2.
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Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools.
Front Physiol. 2016 7():2.
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Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism.
Mol Biosyst. 2016 12(5):1496-506.
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Nucleic Acids Res. 2016 44(12):5529-39.
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Investigating the Combinatory Effects of Biological Networks on Gene Co-expression.
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ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism.
Biochim Biophys Acta. 2016 1861(11):1643-1651.
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Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins.
Diabetologia. 2016 Epub ahead of print
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Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.
Cell Metab. 2016 24(1):172-84.
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Nat Rev Gastroenterol Hepatol. 2016 13(8):439-40.
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Agnarsdóttir M, Sooman L, Bolander A, Strömberg S, Rexhepaj E, Bergqvist M, Ponten F, Gallagher W, Lennartsson J, Ekman S, Uhlen M, Hedstrand H.
SOX10 expression in superficial spreading and nodular malignant melanomas.
Melanoma Res. 2010 20(6):468-78.
PubMed: 20890226 DOI: 10.1097/CMR.0b013e3283403ccd
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Brennan DJ, O'Connor DP, Rexhepaj E, Ponten F, Gallagher WM.
Antibody-based proteomics: fast-tracking molecular diagnostics in oncology.
Nat Rev Cancer. 2010 10(9):605-17.
PubMed: 20720569 DOI: 10.1038/nrc2902
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Ehlén A, Brennan DJ, Nodin B, O'Connor DP, Eberhard J, Alvarado-Kristensson M, Jeffrey IB, Manjer J, Brändstedt J, Uhlén M, Pontén F, Jirström K.
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
J Transl Med. 2010 8:78.
PubMed: 20727170 DOI: 10.1186/1479-5876-8-78
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Lindskog C, Asplund A, Engkvist M, Uhlén M, Korsgren O, Pontén F.
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Discov Med. 2010 9(49):565-78.
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Blokzijl A, Friedman M, Pontén F, Landegren U.
Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine.
J Intern Med. 2010 268(3):232-45.
PubMed: 20695973 DOI: 10.1111/j.1365-2796.2010.02256.x
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Ryan D, Rafferty M, Hegarty S, O'Leary P, Faller W, Gremel G, Bergqvist M, Agnarsdottir M, Strömberg S, Kampf C, Pontén F, Millikan RC, Dervan PA, Gallagher WM.
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
Pigment Cell Melanoma Res. 2010 23(4):542-53.
PubMed: 20465595 DOI: 10.1111/j.1755-148X.2010.00720.x
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| 108 |
Brennan DJ, Brändstedt J, Rexhepaj E, Foley M, Pontén F, Uhlén M, Gallagher WM, O'Connor DP, O'Herlihy C, Jirstrom K.
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
BMC Cancer. 2010 10:125.
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Nord H, Segersten U, Sandgren J, Wester K, Busch C, Menzel U, Komorowski J, Dumanski JP, Malmström PU, Díaz de Ståhl T.
Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma.
Int J Cancer. 2010 126(6):1390-402.
PubMed: 19821490 DOI: 10.1002/ijc.24954
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Borsics T, Lundberg E, Geerts D, Koomoa DL, Koster J, Wester K, Bachmann AS.
Subcellular distribution and expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in malignant glioma: Influence on cell survival and migration.
Cancer Sci. 2010 101(7):1624-31.
PubMed: 20412121 DOI: 10.1111/j.1349-7006.2010.01570.x
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Lundberg E, Uhlén M.
Creation of an antibody-based subcellular protein atlas.
Proteomics. 2010 10(22):3984-96.
PubMed: 20648481 DOI: 10.1002/pmic.201000125
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Schwenk JM, Igel U, Neiman M, Langen H, Becker C, Bjartell A, Ponten F, Wiklund F, Grönberg H, Nilsson P, Uhlen M.
Toward next generation plasma profiling via heat-induced epitope retrieval and array-based assays.
Mol Cell Proteomics. 2010 9(11):2497-507.
PubMed: 20682762 DOI: 10.1074/mcp.M110.001560
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Rockberg J, Löfblom J, Hjelm B, Ståhl S, Uhlén M.
Epitope mapping using gram-positive surface display.
Curr Protoc Immunol. 2010 Chapter 9:Unit9.9.
PubMed: 20814943 DOI: 10.1002/0471142735.im0909s90
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Tassidis H, Brokken LJ, Jirström K, Ehrnström R, Pontén F, Ulmert D, Bjartell A, Härkönen P, Wingren AG.
Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer.
Int J Cancer. 2010 126(10):2296-307.
PubMed: 19795453 DOI: 10.1002/ijc.24917
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Holgersson G, Ekman S, Reizenstein J, Bergqvist M, Pontén F, Uhlén M, Magnusson K, Jonnalagadda P, Asplund A, Strömberg S, Linder A, Blomquist E, Liljeholm M, Lödén B, Hellström K, Bergström S.
Molecular profiling using tissue microarrays as a tool to identify predictive biomarkers in laryngeal cancer treated with radiotherapy.
Cancer Genomics Proteomics 2010 7(1):1-7.
PubMed: 20181625
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Tegel H, Tourle S, Ottosson J, Persson A.
Increased levels of recombinant human proteins with the Escherichia coli strain Rosetta(DE3).
Protein Expr Purif. 2010 69(2):159-67.
PubMed: 19733669 DOI: 10.1016/j.pep.2009.08.017
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Fagerberg L, Jonasson K, von Heijne G, Uhlén M, Berglund L.
Prediction of the human membrane proteome.
Proteomics. 2010 10(6):1141-9.
PubMed: 20175080 DOI: 10.1002/pmic.200900258
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Schwenk JM, Igel U, Kato BS, Nicholson G, Karpe F, Uhlén M, Nilsson P.
Comparative protein profiling of serum and plasma using an antibody suspension bead array approach.
Proteomics. 2010 10(3):532-40.
PubMed: 19953555 DOI: 10.1002/pmic.200900657
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Stadler C, Skogs M, Brismar H, Uhlén M, Lundberg E.
A single fixation protocol for proteome-wide immunofluorescence localization studies.
J Proteomics. 2010 73(6):1067-78.
PubMed: 19896565 DOI: 10.1016/j.jprot.2009.10.012
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Gloriam DE, Orchard S, Bertinetti D, Björling E, Bongcam-Rudloff E, Borrebaeck CA, Bourbeillon J, Bradbury AR, de Daruvar A, Dübel S, Frank R, Gibson TJ, Gold L, Haslam N, Herberg FW, Hiltke T, Hoheisel JD, Kerrien S, Koegl M, Konthur Z, Korn B, Landegren U, Montecchi-Palazzi L, Palcy S, Rodriguez H, Schweinsberg S, Sievert V, Stoevesandt O, Taussig MJ, Ueffing M, Uhlén M, van der Maarel S, Wingren C, Woollard P, Sherman DJ, Hermjakob H.
A community standard format for the representation of protein affinity reagents.
Mol Cell Proteomics. 2010 9(1):1-10.
PubMed: 19674966 DOI: 10.1074/mcp.M900185-MCP200
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Szigyarto CA, Sibbons P, Williams G, Uhlen M, Metcalfe SM.
The E3 ligase axotrophin/MARCH-7: protein expression profiling of human tissues reveals links to adult stem cells.
J Histochem Cytochem. 2010 58(4):301-8.
PubMed: 19901269 DOI: 10.1369/jhc.2009.954420
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Hjelm B, Fernández CD, Löfblom J, Ståhl S, Johannesson H, Rockberg J, Uhlén M.
Exploring epitopes of antibodies toward the human tryptophanyl-tRNA synthetase.
N Biotechnol. 2010 27(2):129-37.
PubMed: 19913117 DOI: 10.1016/j.nbt.2009.11.001
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Paavilainen L, Edvinsson A, Asplund A, Hober S, Kampf C, Pontén F, Wester K.
The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells.
J Histochem Cytochem. 2010 58(3):237-46.
PubMed: 19901271 DOI: 10.1369/jhc.2009.954321
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Tchougounova E, Jiang Y, Bråsäter D, Lindberg N, Kastemar M, Asplund A, Westermark B, Uhrbom L.
Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence.
Oncogene. 2009 28(12):1537-48.
PubMed: 19219070 DOI: 10.1038/onc.2009.9
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Oberg F, Haseeb A, Ahnfelt M, Pontén F, Westermark B, El-Obeid A.
Herbal melanin activates TLR4/NF-kappaB signaling pathway.
Phytomedicine. 2009 16(5):477-84.
PubMed: 19103478 DOI: 10.1016/j.phymed.2008.10.008
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Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tárnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Wagener C, Wagner O, Schmitz G.
Approaching clinical proteomics: current state and future fields of application in cellular proteomics.
Cytometry A. 2009 75(10):816-32.
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Leja J, Essaghir A, Essand M, Wester K, Oberg K, Tötterman TH, Lloyd R, Vasmatzis G, Demoulin JB, Giandomenico V.
Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.
Mod Pathol. 2009 22(2):261-72.
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Qu M, Aronica E, Boer K, Fällmar D, Kumlien E, Nistér M, Wester K, Pontén F, Smits A.
DLG3/SAP102 protein expression in malformations of cortical development: a study of human epileptic cortex by tissue microarray.
Epilepsy Res. 2009 84(1):33-41.
PubMed: 19167192 DOI: 10.1016/j.eplepsyres.2008.12.004
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Newberg JY, Li J, Rao A, Pontén F, Uhlén M, Lundberg E, Murphy RF.
Automated Analysis of Human Protein Atlas Immunofluorescence Images.
Proc IEEE Int Symp Biomed Imaging. 2009 5193229:1023-1026.
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Gaber A, Johansson M, Stenman UH, Hotakainen K, Pontén F, Glimelius B, Bjartell A, Jirström K, Birgisson H.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Br J Cancer. 2009 100(10):1540-8.
PubMed: 19384300 DOI: 10.1038/sj.bjc.6605047
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Paulsson J, Sjöblom T, Micke P, Pontén F, Landberg G, Heldin CH, Bergh J, Brennan DJ, Jirström K, Ostman A.
Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer.
Am J Pathol. 2009 175(1):334-41.
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Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tarnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Verhuven W, Wagener C, Wagner O, Schmitz G.
Approaching clinical proteomics: current state and future fields of application in fluid proteomics.
Clin Chem Lab Med. 2009 47(6):724-44.
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Ghanipour A, Jirström K, Pontén F, Glimelius B, Påhlman L, Birgisson H.
The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer.
Cancer Epidemiol Biomarkers Prev. 2009 18(11):2949-56.
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Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L.
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
PLoS Biol. 2009 7(12):e1000256.
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J Proteomics 2009 73(2):252-66.
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Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic droplets.
Angew Chem Int Ed Engl. 2009 48(14):2518-21.
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Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, Goldbeter A, Hace N, Henney A, Hood L, Iyengar R, Jackson V, Kallioniemi O, Klingmüller U, Kolar P, Kolch W, Kyriakopoulou C, Laplace F, Lehrach H, Marcus F, Matrisian L, Nolan G, Pelkmans L, Potti A, Sander C, Seljak M, Singer D, Sorger P, Stunnenberg H, Superti-Furga G, Uhlen M, Vidal M, Weinstein J, Wigle D, Williams M, Wolkenhauer O, Zhivotovsky B, Zinovyev A, Zupan B.
Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008).
Mol Oncol. 2009 3(1):9-17.
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Discovery of epitopes for targeting the human epidermal growth factor receptor 2 (HER2) with antibodies.
Mol Oncol. 2009 3(3):238-47.
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Gry M, Rimini R, Strömberg S, Asplund A, Pontén F, Uhlén M, Nilsson P.
Correlations between RNA and protein expression profiles in 23 human cell lines.
BMC Genomics. 2009 10:365.
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Jögi A, Brennan DJ, Rydén L, Magnusson K, Fernö M, Stål O, Borgquist S, Uhlen M, Landberg G, Påhlman S, Pontén F, Jirström K.
Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer.
Mod Pathol. 2009 22(12):1564-74.
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Ahlin G, Hilgendorf C, Karlsson J, Szigyarto CA, Uhlén M, Artursson P.
Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs.
Drug Metab Dispos. 2009 37(12):2275-83.
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Control of iron homeostasis by an iron-regulated ubiquitin ligase.
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Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.
Proc Natl Acad Sci U S A. 2009 106(52):22492-7.
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Segersten MU, Edlund EK, Micke P, de la Torre M, Hamberg H, Edvinsson AE, Andersson SE, Malmström PU, Wester HK.
A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer.
BJU Int. 2009 104(11):1780-5.
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A global view of protein expression in human cells, tissues, and organs.
Mol Syst Biol. 2009 5:337.
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Rockberg J, Uhlén M.
Prediction of antibody response using recombinant human protein fragments as antigen.
Protein Sci. 2009 18(11):2346-55.
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Rodriguez H, Snyder M, Uhlén M, Andrews P, Beavis R, Borchers C, Chalkley RJ, Cho SY, Cottingham K, Dunn M, Dylag T, Edgar R, Hare P, Heck AJ, Hirsch RF, Kennedy K, Kolar P, Kraus HJ, Mallick P, Nesvizhskii A, Ping P, Pontén F, Yang L, Yates JR, Stein SE, Hermjakob H, Kinsinger CR, Apweiler R.
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles.
J Proteome Res. 2009 8(7):3689-92.
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Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen.
Proc Natl Acad Sci U S A. 2009 106(11):4396-401.
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Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma.
J Proteome Res. 2009 8(4):1639-46.
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Estigoy CB, Pontén F, Odeberg J, Herbert B, Guilhaus M, Charleston M, Ho JWK, Cameron D, dos Remedios CG.
Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts.
Biophys Rev 2009 1:43-49.
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Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas.
Breast Cancer Res Treat. 2009 118(2):333-43.
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Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Mol Cell Proteomics. 2009 8(7):1612-22.
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Characterization of PrEST-based antibodies towards human Cytokeratin-17.
J Immunol Methods. 2009 342(1-2):20-32.
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J Chromatogr A. 2009 1216(20):4457-64.
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High-throughput protein production - lessons from scaling up from 10 to 288 recombinant proteins per week.
Biotechnol J. 2009 4(1):51-7.
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Biotechnol Appl Biochem. 2009 52(Pt 2):159-66.
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Neurosci Lett. 2008 436(2):171-6.
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The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas.
Cancer Genomics Proteomics 2008 5(6):293-300.
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Borgquist S, Djerbi S, Pontén F, Anagnostaki L, Goldman M, Gaber A, Manjer J, Landberg G, Jirström K.
HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors.
Int J Cancer. 2008 123(5):1146-53.
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Breast Cancer Res. 2008 10(5):R79.
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Asplund A, Gry Björklund M, Sundquist C, Strömberg S, Edlund K, Ostman A, Nilsson P, Pontén F, Lundeberg J.
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma.
Br J Dermatol. 2008 158(3):527-38.
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A new era for proteomics research?
Genome Biol. 2008 9(11):325.
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A pilot project to generate affinity reagents to human proteins.
Nat Methods. 2008 5(10):854-5.
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The Human Protein Atlas - a tool for pathology.
J Pathol. 2008 216(4):387-93.
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Nat Methods. 2008 5(12):1039-45.
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A genecentric Human Protein Atlas for expression profiles based on antibodies.
Mol Cell Proteomics. 2008 7(10):2019-27.
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Mol Cell Proteomics. 2008 7(10):2028-37.
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J Mol Recognit. 2008 22(2):57-64.
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The correlation between cellular size and protein expression levels - normalization for global protein profiling.
J Proteomics. 2008 71(4):448-60.
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J Proteome Res. 2008 7(8):3168-79.
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Berglund L, Björling E, Jonasson K, Rockberg J, Fagerberg L, Al-Khalili Szigyarto C, Sivertsson A, Uhlén M.
A whole-genome bioinformatics approach to selection of antigens for systematic antibody generation.
Proteomics. 2008 8(14):2832-9.
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Affinity as a tool in life science.
Biotechniques. 2008 44(5):649-54.
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| 43 |
Paavilainen L, Wernérus H, Nilsson P, Uhlén M, Hober S, Wester K, Pontén F.
Evaluation of monospecific antibodies: a comparison study with commercial analogs using immunohistochemistry on tissue microarrays.
Appl Immunohistochem Mol Morphol. 2008 16(5):493-502.
PubMed: 18685494 DOI: 10.1097/PAI.0b013e31817c645e
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| 42 |
Berglund L, Andrade J, Odeberg J, Uhlén M.
The epitope space of the human proteome.
Protein Sci. 2008 17(4):606-13.
PubMed: 18359855 DOI: 10.1110/ps.073347208
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| 41 |
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H.
Toward a confocal subcellular atlas of the human proteome.
Mol Cell Proteomics. 2008 7(3):499-508.
PubMed: 18029348 DOI: 10.1074/mcp.M700325-MCP200
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| 40 |
Björling E, Lindskog C, Oksvold P, Linné J, Kampf C, Hober S, Uhlén M, Pontén F.
A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues.
Mol Cell Proteomics. 2008 7(5):825-44.
PubMed: 17913849 DOI: 10.1074/mcp.M700411-MCP200
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| 39 |
Hober S, Uhlén M.
Human protein atlas and the use of microarray technologies.
Curr Opin Biotechnol. 2008 19(1):30-5.
PubMed: 18187316 DOI: 10.1016/j.copbio.2007.11.006
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| 38 |
Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A.
Human Proteinpedia enables sharing of human protein data.
Nat Biotechnol. 2008 26(2):164-7.
PubMed: 18259167 DOI: 10.1038/nbt0208-164
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| 37 |
Nestor M, Ekberg T, Dring J, van Dongen GA, Wester K, Tolmachev V, Anniko M.
Quantification of CD44v6 and EGFR expression in head and neck squamous cell carcinomas using a single-dose radioimmunoassay.
Tumour Biol. 2007 28(5):253-63.
PubMed: 17992053 DOI: 10.1159/000110898
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| 36 |
Sundqvist G, Stenvall M, Berglund H, Ottosson J, Brumer H.
A general, robust method for the quality control of intact proteins using LC-ESI-MS.
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 852(1-2):188-94.
PubMed: 17267305 DOI: 10.1016/j.jchromb.2007.01.011
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| 35 |
Alm T, Steen J, Ottosson J, Hober S.
High-throughput protein purification under denaturating conditions by the use of cation exchange chromatography.
Biotechnol J. 2007 2(6):709-16.
PubMed: 17492715 DOI: 10.1002/biot.200700060
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| 34 |
Renberg B, Nordin J, Merca A, Uhlén M, Feldwisch J, Nygren PA, Karlström AE.
Affibody molecules in protein capture microarrays: evaluation of multidomain ligands and different detection formats.
J Proteome Res. 2007 6(1):171-9.
PubMed: 17203961 DOI: 10.1021/pr060316r
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| 33 |
Mulder J, Wernérus H, Shi TJ, Pontén F, Hober S, Uhlén M, Hökfelt T.
Systematically generated antibodies against human gene products: high throughput screening on sections from the rat nervous system.
Neuroscience. 2007 146(4):1689-703.
PubMed: 17478047 DOI: 10.1016/j.neuroscience.2007.02.054
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| 32 |
Orchard S, Heck A, Uhlen M, Ping P.
Publication Committee meeting. HUPO 5th annual World Congress. Long Beach, CA, USA 30 October 2006.
Proteomics. 2007 7(7):1009-11.
PubMed: 17340644 DOI: 10.1002/pmic.200700015
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| 31 |
Falk R, Ramström M, Ståhl S, Hober S.
Approaches for systematic proteome exploration.
Biomol Eng. 2007 24(2):155-68.
PubMed: 17376740 DOI: 10.1016/j.bioeng.2007.01.001
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| 30 |
Strömberg S, Björklund MG, Asplund C, Sköllermo A, Persson A, Wester K, Kampf C, Nilsson P, Andersson AC, Uhlen M, Kononen J, Ponten F, Asplund A.
A high-throughput strategy for protein profiling in cell microarrays using automated image analysis.
Proteomics. 2007 7(13):2142-50.
PubMed: 17549799 DOI: 10.1002/pmic.200700199
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| 29 |
Uhlen M.
Mapping the human proteome using antibodies
Mol Cell Proteomics 2007 6(8):1455-6.
PubMed: 17703056
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| 28 |
Bengtsson S, Krogh M, Szigyarto CA, Uhlen M, Schedvins K, Silfverswärd C, Linder S, Auer G, Alaiya A, James P.
Large-scale proteomics analysis of human ovarian cancer for biomarkers.
J Proteome Res. 2007 6(4):1440-50.
PubMed: 17315909 DOI: 10.1021/pr060593y
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| 27 |
Lofblom J, Kronqvist N, Uhlen M, Stahl S, Wernerus H.
Optimization of electroporation-mediated transformation: Staphylococcus carnosus as model organism.
J Appl Microbiol 2007 102(3):736-47.
PubMed: 17309623 DOI: 10.1111/j.1365-2672.2006.03127.x
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| 26 |
Lerner M, Corcoran M, Cepeda D, Nielsen ML, Zubarev R, Pontén F, Uhlén M, Hober S, Grandér D, Sangfelt O.
The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD.
Mol Biol Cell. 2007 18(5):1670-82.
PubMed: 17314412 DOI: 10.1091/mbc.E06-03-0248
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| 25 |
Lundberg E, Sundberg M, Gräslund T, Uhlén M, Svahn HA.
A novel method for reproducible fluorescent labeling of small amounts of antibodies on solid phase.
J Immunol Methods. 2007 322(1-2):40-9.
PubMed: 17383674 DOI: 10.1016/j.jim.2007.01.023
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| 24 |
Patrakka J, Xiao Z, Nukui M, Takemoto M, He L, Oddsson A, Perisic L, Kaukinen A, Szigyarto CA, Uhlén M, Jalanko H, Betsholtz C, Tryggvason K.
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik.
J Am Soc Nephrol. 2007 18(3):689-97.
PubMed: 17251388 DOI: 10.1681/ASN.2006060675
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| 23 |
Taussig MJ, Stoevesandt O, Borrebaeck CA, Bradbury AR, Cahill D, Cambillau C, de Daruvar A, Dubel S, Eichler J, Frank R, Gibson TJ, Gloriam D, Gold L, Herberg FW, Hermjakob H, Hoheisel JD, Joos TO, Kallioniemi O, Koegll M, Konthur Z, Korn B, Kremmer E, Krobitsch S, Landegren U, van der Maarel S, McCafferty J, Muyldermans S, Nygren PA, Palcy S, Pluckthun A, Polic B, Przybylski M, Saviranta P, Sawyer A, Sherman DJ, Skerra A, Templin M, Ueffing M, Uhlen M.
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome.
Nature Methods 2007 4(1):13-7.
PubMed: 17195019 DOI: 10.1038/nmeth0107-13
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| 22 |
Schwenk JM, Lindberg J, Sundberg M, Uhlén M, Nilsson P.
Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics.
Mol Cell Proteomics. 2007 6(1):125-32.
PubMed: 17060675 DOI: 10.1074/mcp.T600035-MCP200
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| 21 |
Söderberg O, Gullberg M, Jarvius M, Ridderstråle K, Leuchowius KJ, Jarvius J, Wester K, Hydbring P, Bahram F, Larsson LG, Landegren U.
Direct observation of individual endogenous protein complexes in situ by proximity ligation.
Nat Methods. 2006 3(12):995-1000.
PubMed: 17072308 DOI: 10.1038/nmeth947
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| 20 |
Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput protein purification using an automated set-up for high-yield affinity chromatography.
Protein Expr Purif. 2006 46(2):173-8.
PubMed: 16483795 DOI: 10.1016/j.pep.2005.12.010
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| 19 |
Andrade J, Berglund L, Uhlén M, Odeberg J.
Using Grid technology for computationally intensive applied bioinformatics analyses.
In Silico Biol. 2006 6(6):495-504.
PubMed: 17518760
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| 18 |
Persson A, Hober S, Uhlén M.
A human protein atlas based on antibody proteomics.
Curr Opin Mol Ther. 2006 8(3):185-90.
PubMed: 16774037
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| 17 |
Ek S, Andréasson U, Hober S, Kampf C, Pontén F, Uhlén M, Merz H, Borrebaeck CA.
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Mol Cell Proteomics. 2006 5(6):1072-81.
PubMed: 16524965 DOI: 10.1074/mcp.M600077-MCP200
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| 16 |
Eriksson C, Agaton C, Kånge R, Sundberg M, Nilsson P, Ek B, Uhlén M, Gustafsson M, Hober S.
Microfluidic analysis of antibody specificity in a compact disk format.
J Proteome Res. 2006 5(7):1568-74.
PubMed: 16823963 DOI: 10.1021/pr050447c
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| 15 |
Haab BB, Paulovich AG, Anderson NL, Clark AM, Downing GJ, Hermjakob H, Labaer J, Uhlen M.
A reagent resource to identify proteins and peptides of interest for the cancer community: a workshop report.
Mol Cell Proteomics. 2006 5(10):1996-2007.
PubMed: 16867976 DOI: 10.1074/mcp.T600020-MCP200
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| 14 |
Larsson K, Wester K, Nilsson P, Uhlén M, Hober S, Wernérus H.
Multiplexed PrEST immunization for high-throughput affinity proteomics.
J Immunol Methods. 2006 315(1-2):110-20.
PubMed: 16949094 DOI: 10.1016/j.jim.2006.07.014
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| 13 |
Andersson AC, Strömberg S, Bäckvall H, Kampf C, Uhlen M, Wester K, Pontén F.
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J Histochem Cytochem. 2006 54(12):1413-23.
PubMed: 16957166 DOI: 10.1369/jhc.6A7001.2006
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| 12 |
Rada-Iglesias A, Wallerman O, Koch C, Ameur A, Enroth S, Clelland G, Wester K, Wilcox S, Dovey OM, Ellis PD, Wraight VL, James K, Andrews R, Langford C, Dhami P, Carter N, Vetrie D, Pontén F, Komorowski J, Dunham I, Wadelius C.
Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.
Hum Mol Genet. 2005 14(22):3435-47.
PubMed: 16221759 DOI: 10.1093/hmg/ddi378
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| 11 |
Janzi M, Odling J, Pan-Hammarström Q, Sundberg M, Lundeberg J, Uhlén M, Hammarström L, Nilsson P.
Serum microarrays for large scale screening of protein levels.
Mol Cell Proteomics. 2005 4(12):1942-7.
PubMed: 16131484 DOI: 10.1074/mcp.M500213-MCP200
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| 10 |
Nilsson P, Paavilainen L, Larsson K, Odling J, Sundberg M, Andersson AC, Kampf C, Persson A, Al-Khalili Szigyarto C, Ottosson J, Björling E, Hober S, Wernérus H, Wester K, Pontén F, Uhlen M.
Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling.
Proteomics. 2005 5(17):4327-37.
PubMed: 16237735 DOI: 10.1002/pmic.200500072
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| 9 |
Hedhammar M, Stenvall M, Lönneborg R, Nord O, Sjölin O, Brismar H, Uhlén M, Ottosson J, Hober S.
A novel flow cytometry-based method for analysis of expression levels in Escherichia coli, giving information about precipitated and soluble protein.
J Biotechnol. 2005 119(2):133-46.
PubMed: 15996784 DOI: 10.1016/j.jbiotec.2005.03.024
|
| 8 |
Stenvall M, Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput solubility assay for purified recombinant protein immunogens.
Biochim Biophys Acta. 2005 1752(1):6-10.
PubMed: 16084133 DOI: 10.1016/j.bbapap.2005.07.002
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| 7 |
Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
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| 6 |
Lindskog M, Rockberg J, Uhlen M, Sterky F.
Selection of protein epitopes for antibody production
Biotechniques 2005 38(5):723-7.
PubMed: 15945371
|
| 5 |
Uhlen M, Ponten F.
Antibody-based proteomics for human tissue profiling.
Mol Cell Proteomics. 2005 4(4):384-93.
PubMed: 15695805 DOI: 10.1074/mcp.R500009-MCP200
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| 4 |
Kampf C, Andersson A-C, Wester K, Björling E, Uhlen M, Ponten F
Antibody-based tissue profiling as a tool in clinical proteomics
Clin. Proteomics 2004 1(3-4):285-300.
DOI: 10.1385/CP:1:3-4:285
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| 3 |
Agaton C, Uhlén M, Hober S.
Genome-based proteomics.
Electrophoresis. 2004 25(9):1280-8.
PubMed: 15174050 DOI: 10.1002/elps.200405846
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| 2 |
Agaton C, Falk R, Hoiden Guthenberg I, Gostring L, Uhlen M, Hober S.
Selective enrichment of monospecific polyclonal antibodies for antibody-based proteomics efforts.
J Chromatogr A 2004 16;1043(1):33-40.
PubMed: 15317410
|
| 1 |
Agaton C, Galli J, Höidén Guthenberg I, Janzon L, Hansson M, Asplund A, Brundell E, Lindberg S, Ruthberg I, Wester K, Wurtz D, Höög C, Lundeberg J, Ståhl S, Pontén F, Uhlén M.
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues.
Mol Cell Proteomics. 2003 2(6):405-14.
PubMed: 12796447 DOI: 10.1074/mcp.M300022-MCP200
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