Mitosis is the fundamental process by which genetic information is passed from a parental cell to two daughter cells. The crucial role of the microtubule cytoskeleton and the centrosomes in this process is well known, and still early mouse embryo lack centrosomes. In a study published in Cell researches have found an explanation to this paradox...Read more

Recently, Sweden's leading business newspaper Dagens Industri published an in-depth interview with HPA Director, professor Mathias Uhlén, about the global race to build a virtual cell - a next frontier in biomedical AI. The article compares major global initiatives such as AlphaFold, the Chan Zuckerberg Initiative, and China's Pi-HuB project, and highlights the Swedish effort Alpha Cell...Read more

The cell cycle is fundamental for life, enabling organisms to grow, heal, reproduce, and maintain cellular function. In the subcellular resource of the Human Protein Atlas protein imaging and single cell RNAseq analysis have been used to explore cell-to-cell variability and the cell cycle dependent proteome...Read more

In an article published in Genome Medicine HPA related researchers have used advanced multi-omics analysis to investigate the impact of genetics and environment on the metabolic profiles of healthy adults by tracking metabolic changes over a two-year period...Read more

In the endoplasmic reticulum (ER), ATP is essential for the folding, maturation, transport and degradation of proteins. As there is no pathway for endogenous ATP synthesis in the ER, these constant processes all rely on ATP import from the cytosol, but it is not until recently that the responsible transporter has been identified...Read more