The mucus acinus-specific expression pattern of BPI fold containing family B member 2 (gene: BPIFB2) in salivary gland is highlighted by multiplex immunohistochemistry (mIHC/IF)...Read more

This week, we explore a fascinating protein that regulates the unfolded protein response (UPR) in eukaryotic cells in an unusual manner - by sensing the accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen and conveying this information to the nucleus. This is achieved through unconventional splicing of the XBP1 mRNA in the cytoplasm leading to the induction of a transcriptional program in the nucleus. Hence its apt name - Endoplasmic Reticulum to Nucleus Signaling, ERN1...Read more

The localization of Calaxin (gene: CLXN) in ciliated cells is highlighted in fallopian tube by multiplex immunohistochemistry (mIHC/IF)...Read more

Meiosis-associated Boule homolog, RNA binding protein (gene: BOLL) is localized to mid-stage developing sperm in testis with multiplex immunohistochemistry (mIHC/IF)...Read more

The proximal tubule-specific catabolic enzyme myo-inositol oxygenase (gene: MIOX) is highlighted in kidney through multiplex immunohistochemistry (mIHC/IF)...Read more