News Articles


Multiplex tissue image of the month - CRACR2A in salivary gland

News image of the month April 2025 CRACR2A salivary gland.PNG

Calcium release activated channel regulator 2A (gene: CRACR2A) displays a diverse expression pattern in the salivary gland...Read more


A highly multiplexed reference map of human tissues

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Since the release of HPA v24, we are providing a unique highly-multiplexed data set showing the distribution of a large set of reference markers across all major tissues and organs in the human body. The images have been generated using CODEX technology for simultaneous immunostaining of 47 marker proteins across the panel of normal HPA tissue microarrays. The markers have been selected to help distinguish different tissue structures and cell types, and thus histological features, in the TMAs...Read more


Multiplex tissue image of the month - CFAP45 in endometrium

News image of the month March 2025 CFAP45 endometrium glands merge.PNG

This month, cilia and flagella associated protein 45 (gene: CFAP45) is highlighted among the sparse population of ciliated cells in endometrial glands through the use of multiplex immunohistochemistry (mIHC/IF)...Read more


Multiplex tissue image of the month - NES in kidney

News image of the month February 2025 NES 2.PNG

The intermediate filament protein nestin (gene: NES) is highlighted in kidney through multiplex immunohistochemistry (mIHC/IF)...Read more


Building a high-resolution map of proteins in sperm

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Sperm cells are highly specialized for their function in reproduction and have a unique structure among the human cell types. Similarly, the repertoire of proteins that are present in sperm comprise many cell-type specific components. Researchers affiliated with the Human Protein Atlas have started to map proteins in human sperm using immunofluorescence and confocal microscopy to complement and further build on the comprehensive studies of the sperm proteome that so far mainly have been performed using mass spectrometry. This new approach gives a detailed view of the presence and subcellular localization of proteins in sperm, with single-cell resolution...Read more