News Articles


Multiplex tissue image of the month - IGF2BP1 in testis

News image of the month May 2025 IGF2BP1 testis spermatogonia.PNG

Insulin like growth factor 2 mRNA binding protein 1 (gene: IGF2BP1) is localized to undifferentiated sperm cells in testis...Read more


HPA data contributes to multimodal cell maps

music2.PNG

In 2021, Trey Idekers team at UCLA in collaboration with Emma Lundbergs team at KTH and Stanford presented a new way of creating hierarchical maps of subcellular protein organization by integrating data from immunofluorescence images from the HPA with protein interaction data. The resulting cell map was referred to as the multi-scale integrated cell (MuSIC 1.0). Four years later, the same team has now released the next version of such a multimodal cell map, again accompanied by a prestigious publication in Nature...Read more


Multiplex tissue image of the month - CRACR2A in salivary gland

News image of the month April 2025 CRACR2A salivary gland.PNG

Calcium release activated channel regulator 2A (gene: CRACR2A) displays a diverse expression pattern in the salivary gland...Read more


A highly multiplexed reference map of human tissues

multiplextissue_codex.png

Since the release of HPA v24, we are providing a unique highly-multiplexed data set showing the distribution of a large set of reference markers across all major tissues and organs in the human body. The images have been generated using CODEX technology for simultaneous immunostaining of 47 marker proteins across the panel of normal HPA tissue microarrays. The markers have been selected to help distinguish different tissue structures and cell types, and thus histological features, in the TMAs...Read more


Multiplex tissue image of the month - CFAP45 in endometrium

News image of the month March 2025 CFAP45 endometrium glands merge.PNG

This month, cilia and flagella associated protein 45 (gene: CFAP45) is highlighted among the sparse population of ciliated cells in endometrial glands through the use of multiplex immunohistochemistry (mIHC/IF)...Read more