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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA025735
Strong cytoplasmic and nuclear positivity was observed in neuronal cells and in a subset of renal tubules. The gastrointestinal tract, placenta, testis and reaction center cells in lymphoid tissues showed weak to moderate cytoplasmic positivity. Remaining normal cells were weakly stained or negative.
HPA025762
Normal tissues were in general negative or displayed weak cytoplasmic positivity. Strong cytoplasmic and occasional nuclear staining was observed in neuronal cells, testicular Leydig cells and decidual cells in placenta. Cells in seminiferus ducts, lymphoid reaction centers, endothelium and skeletal muscle were moderately stained.
The Human Protein Atlas project is funded
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