Brain tissue expression of FRMD4B - Mouse brain

MOUSE BRAIN TISSUE

Gene description	FERM domain containing 4B
Mouse gene	ENSMUSG00000030064 (version 92)
Annotation summary	Diffuse-synaptic labelling in multiple brain regions with variable intensities. Moderate-strong in olfactory bulb granular layer and olfactory nerve layer, taenia tecta, ventral pallidum, BNST, lateral septum, thalamus stria terminalis, globus pallidus, caudate putamen, neocortex deeper layers (V-VI), ventromedial hypothalamic nucleus, mossy fibers in the hippocampus, amygdala nuclei, periaqueductal gray metter, dorsal raphe, substantia nigra reticular part, cerebellar Purkinje cell dendritic arborization in the molecular layer.
Positive cells and structuresⁱ Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain. Read more	Dendrite, axon and synapse in neurons.

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Thalamus

Basal ganglia

Hippocampus

Cerebellum

	Protein
	Relative fluorescence intensityⁱ Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity . Read more
Mouse brain region	255 0
Olfactory bulb
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)
Cerebral cortex
Frontal association cortex (fra)
Motor cortex (m)
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
Hippocampus
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
Amygdala
Nucleus of the lateral olfactory tract (lot)
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
Basal ganglia
Dorsal tenia tecta (dtt)
Caudate putamen (cpu)
Accumbens nucleus, core (acbc)
Accumbens nucleus, shell (acbsh)
Island of Calleja (icj)
Ventral pallidum (vp)
Medial septum (ms)
Nucleus of the vertical limb of the diagonal band (vdb)
Lateral septum (ls)
Nucleus of the horizontal limb of the diagonal band (hdb)
Globus pallidus (gp)
Hypothalamus
Dorsal tuberomammillary nucleus (dtm)	N/A
Mammillary nucleus (mn)
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm)
Lateral preoptic area (lpo)
Medial preoptic area (mpo)
Suprachiasmatic nucleus (sch)
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Arcuate nucleus (arc)
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
Thalamus
Medial geniculate nucleus (mg)	N/A
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
Stria terminalis (st)
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl)	N/A
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)
Midbrain motor
Substantia nigra, reticular (snr)	N/A
Periaquaductal grey (pag)
Interpeduncular nucleus (ip)	N/A
Mesencephalic retic form (mrt)
Red nucleus (r)	N/A
Oculomotor nucleus (3n)
Mesencephalic trigeminal nucleus (me5)	N/A
Ventral tegmental area (vta)	N/A
Midbrain behavioral
Substantia nigra, compact (snc)	N/A
Dorsal raphe nucleus (dr)
Median raphe nucleus (mnr)	N/A
Midbrain sensory
Superior colliculi (sc)
External cortical inferior colliculli (ecic)
Pons
Barrington's nucleus (bar)	N/A
Koelliker-fuse nucleus (kf)	N/A
Motor tregiminal nucleus (5n)
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)	N/A
Pontine nucleus (pn)	N/A
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)	N/A
Medulla
Nucleus of the solitary tract (sol)
Raphe magnus nucleus (rmg)
Cochlear nucleus (cn)
Lateral paragigantocellular nucleus (lpg)
Raphe pallidus nucleus (rpa)
Facial nucleus (7n)
Hypoglossal nucleus (12n)
Ambiguus nucleus (amb)
External cuneate nucleus (ecu)
Inferior olivary nucleus (io)
Raphe obscures nucleus (rob)
Dorsal motor nucleus of vagus (10n)
Cerebellum
Vestibulocerebellar nucleus (vecb)	N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
Circumventricular organs
Subcommissural organ (sco)
Subfornical organ (sfo)
Median eminence (me)
Medulla (ap)	N/A

Antibodies in assayⁱ The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.
HPA009705