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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA027137
Strong cytoplasmic positivity was displayed in islets of Langerhans. Fallopian tube, gallbladder, subset of renal tubules and subset of cells in seminiferus ducts were moderately stained. Purkinje cells and neuronal cells showed moderate to strong cytoplasmic and/or nuclear staining. Weak to moderate cytoplasmic and membranous staining was observed in stomach and small intestine. Remaining normal tissues were weakly stained or generally negative.
HPA045760
Purkinje cells, islets of Langerhans and squamous epithelia of tonsil displayed strong cytoplasmic staining. Intestine, fallopian tube, gallbladder, kidney, stomach, red pulp of spleen and glandular cells of uterus were moderately positive with additional nuclear staining in neuronal cells of lateral ventricle and chondrocytes. Remaining normal tissues were weakly stained or negative.
HPA050590
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Strong staining was observed in pancreatic islets. Additional nuclear staining was observed in neuronal and Purkinje cells. Respiratory epithelia, liver, skin, trophoblastic cells, spleen and muscle were negative.
The Human Protein Atlas project is funded
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