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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA065539
Subset of neuronal cells exhibited strong cytoplasmic and nuclear positivity. Adrenal gland, keratinocytes and Leydig cells along with subset of cells in renal tubules and nasopharynx showed moderate cytoplasmic positivity. Additional membranous immunoreactivity was observed in hepatocytes and subset of decidual cells. Remaining normal tissues were weakly stained or mostly negative.
HPA068768
Hepatocytes, renal tubule cells, Leydig cells and neuronal cells displayed strong cytoplasmic immunoreactivity. Extracellular material and plasma were distinctly stained. Remaining normal tissues were weakly stained or negative.
CAB008363
Strong cytoplasmic staining in a subset of neurons in the CNS. Additional strong staining of leydig cells in testis and adrenal gland. Remaining tissues were either weakly stained or negative.
CAB069921
Distinct plasma positivity in most tissues. Strong cytoplasmic staining in subsets of neurons whereas hepatocytes, adrenal gland, Leydig cells and a few other tissues showed weak to moderate positivity. Remaining tissues were mainly negative.