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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression (NX) levels for human tissues was created by combining the data from these three transcriptomics datasets (HPA, GTEx and FANTOM5).
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA012763
Glial cells
Not detected
Neuronal cells
Not detected
Neuronal projections
Medium
Synapses
Not detected
SUBSTANTIA NIGRA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody CAB016249
Glial cells
Not detected
Neuronal cells
Not detected
Neuronal projections
High
Synapses
Medium
SUBSTANTIA NIGRA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody CAB078172
Glial cells
Not detected
Neuronal cells
High
Neuronal projections
High
Synapses
High
SUBSTANTIA NIGRA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as average pTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. pTPM values of the individual samples are presented next to the box plot.
Max pTPM: 451.6
Min pTPM: 0.0
Std pTPM: 106.4
Median pTPM: 56.2
GTEX-15ER7-0011-R2a-SM-6M46O
20-29 years, female
451.6
GTEX-15CHQ-0011-R2b-SM-6AJAD
60-69 years, male
425.2
GTEX-13OW6-0011-R2a-SM-5L3HG
50-59 years, male
424.8
GTEX-1313W-0011-R2a-SM-5EGLF
50-59 years, female
379.1
GTEX-13O3Q-0011-R2b-SM-5KM3K
50-59 years, male
306.8
GTEX-1B933-0011-R2b-SM-7IGNM
50-59 years, female
290.7
GTEX-X585-0011-R2B-SM-46MVF
50-59 years, male
268.3
GTEX-1399T-0011-R2b-SM-5DUXM
60-69 years, male
266.8
GTEX-15DYW-0011-R2b-SM-7KUKY
60-69 years, female
256.6
GTEX-12ZZX-0011-R2a-SM-5EGLG
40-49 years, female
225.4
GTEX-WHSE-0011-R2A-SM-3P5ZL
20-29 years, male
205.5
GTEX-XLM4-0011-R2B-SM-4AT5Z
60-69 years, male
189.5
GTEX-13G51-0011-R2b-SM-5LZXS
60-69 years, male
187.0
GTEX-13SLX-0011-R2b-SM-5S2VP
50-59 years, female
186.0
GTEX-T6MN-0011-R2A-SM-32QOW
50-59 years, male
169.7
GTEX-QMR6-0011-R2A-SM-32PKV
50-59 years, male
160.9
GTEX-13FXS-0011-R2b-SM-5K7XX
50-59 years, male
160.1
GTEX-14BIN-0011-R2a-SM-5S2RJ
50-59 years, female
154.0
GTEX-13RTJ-0011-R2a-SM-5PNW9
60-69 years, male
149.0
GTEX-T2IS-0011-R2A-SM-32QPF
20-29 years, female
146.1
GTEX-14C5O-0011-R2a-SM-5ZZV2
60-69 years, male
145.1
GTEX-145LS-0011-R2a-SM-5PNZI
60-69 years, female
139.9
GTEX-13OW8-0011-R2a-SM-5L3G2
60-69 years, male
139.4
GTEX-13O3O-0011-R2b-SM-5P9H1
60-69 years, female
138.7
GTEX-14BIM-0011-R2b-SM-69LQ6
60-69 years, female
127.2
GTEX-15DCD-0011-R2b-SM-6LPIE
70-79 years, female
107.6
GTEX-11GSO-0011-R2a-SM-57WDF
60-69 years, male
107.4
GTEX-13N2G-0011-R2a-SM-5MR4Q
60-69 years, male
106.7
GTEX-12WSF-0011-R2a-SM-5DUVU
70-79 years, male
103.8
GTEX-YFC4-0011-R2a-SM-4V6DZ
40-49 years, female
99.2
GTEX-1A3MX-0011-R2b-SM-7EWFL
60-69 years, male
98.5
GTEX-T5JC-0011-R2A-SM-32PLZ
20-29 years, male
93.4
GTEX-13NYS-0011-R2b-SM-5MR4G
60-69 years, male
90.5
GTEX-15RJE-0011-R2b-SM-79OMP
40-49 years, male
88.0
GTEX-12WSD-0011-R2a-SM-5LZWB
60-69 years, female
82.9
GTEX-14JG1-0011-R2a-SM-5ZZVE
40-49 years, male
76.0
GTEX-13QJC-0011-R2b-SM-5PNUN
60-69 years, female
71.6
GTEX-14ASI-0011-R2b-SM-5YY9H
60-69 years, male
70.1
GTEX-NPJ7-0011-R2a-SM-2I3GF
60-69 years, female
65.6
GTEX-14PN4-0011-R2a-SM-6EU2Y
50-59 years, male
64.0
GTEX-147GR-0011-R2b-SM-5S2RQ
60-69 years, male
61.5
GTEX-17EVP-0011-R2a-SM-7LG4W
40-49 years, male
59.0
GTEX-16Z82-0011-R2b-SM-79OK9
60-69 years, male
58.0
GTEX-1B996-0011-R2a-SM-7IGON
60-69 years, male
56.4
GTEX-S7SE-0011-R2A-SM-2XCDC
50-59 years, male
56.1
GTEX-QDT8-0011-R2A-SM-32PKQ
30-39 years, female
52.0
GTEX-11PRG-0011-R2a-SM-69LQ5
50-59 years, male
46.1
GTEX-14PJO-0011-R2a-SM-5ZZVF
60-69 years, male
40.0
GTEX-18464-0011-R2a-SM-731AL
50-59 years, male
29.4
GTEX-11ZTS-0011-R2b-SM-5BC75
60-69 years, female
28.1
GTEX-ZV68-0011-R2a-SM-4YCDK
50-59 years, female
21.7
GTEX-1A8G7-0011-R2a-SM-7IGQI
60-69 years, male
21.0
GTEX-RU72-0011-R2A-SM-2TF6O
50-59 years, female
20.6
GTEX-XMD1-0011-R2B-SM-4AT5N
60-69 years, male
20.6
GTEX-13X6K-0011-R2b-SM-5P9K3
60-69 years, female
20.5
GTEX-NL4W-0011-R2a-SM-2I5GV
50-59 years, male
19.7
GTEX-13CF2-0011-R2a-SM-5L3DC
60-69 years, male
18.2
GTEX-1B8SG-0011-R2b-SM-79OOT
50-59 years, male
15.6
GTEX-ZAB4-0011-R2a-SM-4RGNP
40-49 years, male
15.5
GTEX-NPJ8-0011-R2a-SM-2TC6M
40-49 years, male
14.3
GTEX-15EO6-0011-R2a-SM-6M46R
50-59 years, male
14.0
GTEX-12WSA-0011-R2a-SM-57WDK
60-69 years, male
12.2
GTEX-PWO3-0011-R2A-SM-2S1OX
60-69 years, female
11.5
GTEX-131XH-0011-R2b-SM-5DUVY
50-59 years, male
9.7
GTEX-12WSH-0011-R2a-SM-5GU68
50-59 years, male
9.1
GTEX-13OVJ-0011-R2b-SM-5L3GP
50-59 years, female
9.1
GTEX-13X6I-0011-R2b-SM-5PNWQ
60-69 years, male
8.0
GTEX-YJ89-0011-R2b-SM-4RGLT
60-69 years, male
8.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z
60-69 years, male
7.6
GTEX-13PDP-0011-R2b-SM-5O9DH
60-69 years, male
4.5
GTEX-1445S-0011-R2b-SM-5PNUH
60-69 years, male
3.7
GTEX-ZDXO-0011-R2b-SM-4WKFG
60-69 years, male
2.2
GTEX-13SLW-0011-R2b-SM-5O9C6
70-79 years, male
1.8
GTEX-UTHO-0011-R2A-SM-3GIKC
60-69 years, male
1.1
GTEX-OHPN-0011-R2A-SM-2I5FB
60-69 years, female
0.8
GTEX-Z93S-0011-R2a-SM-4RGNG
50-59 years, male
0.6
GTEX-11UD1-0011-R2b-SM-5BC6O
40-49 years, female
0.4
GTEX-Q2AG-0011-R2A-SM-2HMIT
40-49 years, female
0.3
GTEX-QVJO-0011-R2A-SM-2S1QK
60-69 years, female
0.3
GTEX-N7MS-0011-R2a-SM-2HML6
60-69 years, male
0.2
GTEX-N7MT-0011-R2a-SM-2I3GI
60-69 years, female
0.2
GTEX-139TS-0011-R2b-SM-5J1MX
60-69 years, male
0.0
GTEX-13NYB-0011-R2a-SM-5MR3C
40-49 years, male
0.0
GTEX-OXRO-0011-R2A-SM-3NB1W
60-69 years, female
0.0
GTEX-WL46-0011-R2A-SM-3LK6O
50-59 years, male
0.0
GTEX-WVLH-0011-R2A-SM-3MJFJ
50-59 years, male
0.0
GTEX-X4XX-0011-R2A-SM-3P623
60-69 years, male
0.0
GTEX-ZE9C-0011-R2a-SM-4WKGH
60-69 years, male
0.0
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SUBSTANTIA NIGRA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. pTPM values of the individual samples are presented next to the box plot.