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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA005741
Most normal tissues showed moderate to strong cytoplasmic immunoreactivity. Strongest staining was observed in bronchus and thyroid gland. Most lymphoid tissues and cells of the CNS were negative.
HPA011731
Strong cytoplasmic and nuclear positivity was observed in colorectal glands, hepatocytes and in a subset of alveolar cells. Moderate staining was observed gastrointestinal tract, renal tubules, breast, thyroid gland, subsets of cells in bone marrow and red pulp of spleen. Remaining normal tissues were weakly stained or negative.
CAB008366
Respiratory epithelial cells, pneumocytes, colon and thyroid gland showed strong cytoplasmic and/or nuclear staining. Gastrointestinal, hepatocytes, gall bladder, fallopian tube, Leydig cells and epididymis showed moderate positivity. Most remaining normal cells were weakly stained or negative.
The Human Protein Atlas project is funded
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