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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA023501
Normal tissues showed moderate to strong cytoplasmic and nuclear staining. Decidual cells, breast and squamous epithelium of esophagus and tonsil displayed strong cytoplasmic immunoreactivity. Gastrointestinal glands and exocrine pancreas showed strong cytoplasmic and nuclear immunoreactivity. Parathyroid gland, bile duct cells and germinal center cells of the lymphoid tissues were negative or weakly stained.
CAB005032
Strong cytoplasmic and nuclear staining was observed in exocrine pancreas and the gastrointestinal tract. Normal tissues in general showed weak to moderate positivity.
CAB005039
Strong cytoplasmic staining in gastrointestinal tract and exocrine pancreas. Squamous epithelia showed strong cytoplasmic staining in the basal layers. Strong staining in basal cells was found in prostate. Weak to moderate staining in a few other tissues.
The Human Protein Atlas project is funded
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