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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA043123
Inflammatory cells along with cells in red pulp of spleen and hematopoietic cells showed distinct cytoplasmic staining. The heart displayed strong positivity in cytoplasmic and intercalated discs. Weak to moderate positivity was observed in squamous epithelia and skeletal muscle. Remaining normal tissues were negative.
HPA046836
Normal tissues generally displayed weak to moderate cytoplasmic staining. Thyroid, hematopoietic cells, neuronal cells in hippocampus and decidual cells were strongly positive. Strong nuclear staining was observed in seminiferus duct cells. Bile duct cells and islets of Langerhans were negative.
HPA059494
The large intestine, Leydig cells, renal tubules and fractions of cells in exocrine pancreas showed strong cytoplasmic positivity. Smooth muscle cells displayed moderate immunoreactivity. Remaining normal tissues were in general weakly stained or negative.
The Human Protein Atlas project is funded
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