Nuclear bodies

 Staining of nuclear bodies in human cell line A-431 (HPA005963)
Scale bar represents 10µm

Nuclear bodies

Nuclear bodies is a collective term for several non-membrane bound nuclear sub-compartment including: Cajal bodies (CB), Gemini of Cajal bodies (gems) and promyelocytic leukemia bodies (PML). CB are involved in RNA splicing whereas PML bodies are thought to perform a multitude of tasks including apoptosis regulation.

Immunofluorescent staining

Nuclear bodies are visible as distinct spots in the nucleoplasm. They can vary in number and size depending on the cell line.

Read more about the nuclear proteome.