In a publication in Cancers a comprehensive mass spectrometry strategy was used to profile blood plasma samples from a large pan-cancer cohort including 15 different cancer types. Differential expression analysis and machine learning was then used to identify a potential biomarker panel able to correctly diagnose multiple myeloma...Read more

An interview with the Director of the Human Protein Atlas was recently published online in Technology Networks by the editor Molly Campbell...Read more

Pyruvate kinase muscle type (PKM) is a key enzyme in glycolysis and is a mediator of the Warburg effect in tumors. The association of PKM with survival of cancer patients is controversial. This study investigated the associations of the alternatively spliced transcripts of PKM with cancer patients' survival outcomes and explained the conflicts in previous studies. The article has recently been published in the journal Cancers...Read more

Over time, cells accumulate DNA mutations, that if transcribed and translated influence gene expression and/or function of the protein. The increasing number mutations in eg. genes that control cell division eventually lead formation of tumor...Read more

Cancer rates are steadily increasing worldwide and are projected to continue to rise during the next decade. But what part of it is a true increase and what part is influenced by other factors, such as reporting and quality of various cancer registries, is unclear. In this week's blog post, we will highlight some of the common terms used when discussing cancer statistics and what to consider when interpreting it...Read more